CDC59_RS16475 5fd067c95ef5a9ad834adb0bd5c0784a 457 Pfam PF17158 Membrane-associated sensor, integral membrane domain 51 281 5.2E-27 T 29-03-2018 IPR033424 Membrane-associated sensor domain CDC59_RS16475 5fd067c95ef5a9ad834adb0bd5c0784a 457 SUPERFAMILY SSF55073 305 456 8.63E-37 T 29-03-2018 IPR029787 Nucleotide cyclase CDC59_RS16475 5fd067c95ef5a9ad834adb0bd5c0784a 457 Pfam PF00990 Diguanylate cyclase, GGDEF domain 300 456 2.8E-40 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS16475 5fd067c95ef5a9ad834adb0bd5c0784a 457 Gene3D G3DSA:3.30.70.270 293 457 2.3E-45 T 29-03-2018 CDC59_RS16475 5fd067c95ef5a9ad834adb0bd5c0784a 457 SMART SM00267 289 457 3.9E-45 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS16475 5fd067c95ef5a9ad834adb0bd5c0784a 457 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 296 456 2.5E-35 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS08745 c7b66d4286c7d79aa5bddd7b86a4a814 123 Pfam PF00893 Small Multidrug Resistance protein 47 113 1.0E-7 T 29-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 CDC59_RS08745 c7b66d4286c7d79aa5bddd7b86a4a814 123 SUPERFAMILY SSF103481 50 122 3.14E-14 T 29-03-2018 CDC59_RS15800 9a34a390acbc77345864293286858d85 880 TIGRFAM TIGR01056 topB: DNA topoisomerase III 3 617 1.4E-172 T 29-03-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 CDC59_RS15800 9a34a390acbc77345864293286858d85 880 Pfam PF01751 Toprim domain 5 130 8.4E-10 T 29-03-2018 IPR006171 TOPRIM domain CDC59_RS15800 9a34a390acbc77345864293286858d85 880 Gene3D G3DSA:1.10.460.10 159 357 3.9E-39 T 29-03-2018 CDC59_RS15800 9a34a390acbc77345864293286858d85 880 Gene3D G3DSA:1.10.460.10 488 619 6.2E-21 T 29-03-2018 CDC59_RS15800 9a34a390acbc77345864293286858d85 880 SMART SM00437 279 559 5.1E-76 T 29-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 CDC59_RS15800 9a34a390acbc77345864293286858d85 880 Pfam PF13342 C-terminal repeat of topoisomerase 757 817 2.7E-18 T 29-03-2018 IPR025589 Topoisomerase C-terminal repeat CDC59_RS15800 9a34a390acbc77345864293286858d85 880 Pfam PF13342 C-terminal repeat of topoisomerase 649 710 2.5E-20 T 29-03-2018 IPR025589 Topoisomerase C-terminal repeat CDC59_RS15800 9a34a390acbc77345864293286858d85 880 Pfam PF01131 DNA topoisomerase 156 597 8.8E-118 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CDC59_RS15800 9a34a390acbc77345864293286858d85 880 Gene3D G3DSA:3.40.50.140 3 154 7.6E-34 T 29-03-2018 CDC59_RS15800 9a34a390acbc77345864293286858d85 880 SMART SM00436 126 221 6.0E-24 T 29-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 CDC59_RS15800 9a34a390acbc77345864293286858d85 880 Gene3D G3DSA:2.70.20.10 368 487 5.2E-26 T 29-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 CDC59_RS15800 9a34a390acbc77345864293286858d85 880 SUPERFAMILY SSF56712 3 612 7.19E-175 T 29-03-2018 IPR023405 DNA topoisomerase, type IA, core domain CDC59_RS15800 9a34a390acbc77345864293286858d85 880 SMART SM00493 3 126 5.8E-11 T 29-03-2018 IPR006171 TOPRIM domain CDC59_RS15800 9a34a390acbc77345864293286858d85 880 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 316 331 - T 29-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 CDC59_RS15800 9a34a390acbc77345864293286858d85 880 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 405 421 3.9E-27 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CDC59_RS15800 9a34a390acbc77345864293286858d85 880 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 100 113 3.9E-27 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CDC59_RS15800 9a34a390acbc77345864293286858d85 880 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 191 209 3.9E-27 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CDC59_RS15800 9a34a390acbc77345864293286858d85 880 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 522 536 3.9E-27 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CDC59_RS15800 9a34a390acbc77345864293286858d85 880 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 322 331 3.9E-27 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CDC59_RS19670 a6551cb1cbeb4d880fc89cf5a7bd2459 925 SUPERFAMILY SSF69279 23 212 1.08E-47 T 29-03-2018 CDC59_RS19670 a6551cb1cbeb4d880fc89cf5a7bd2459 925 Gene3D G3DSA:2.40.50.230 438 534 5.4E-30 T 29-03-2018 IPR006531 Gp5 N-terminal CDC59_RS19670 a6551cb1cbeb4d880fc89cf5a7bd2459 925 Gene3D G3DSA:3.55.50.10 113 217 1.3E-26 T 29-03-2018 CDC59_RS19670 a6551cb1cbeb4d880fc89cf5a7bd2459 925 TIGRFAM TIGR01646 vgr_GE: Rhs element Vgr protein 36 538 6.5E-80 T 29-03-2018 IPR006533 Type VI secretion system, RhsGE-associated Vgr protein CDC59_RS19670 a6551cb1cbeb4d880fc89cf5a7bd2459 925 SUPERFAMILY SSF69255 432 533 1.52E-22 T 29-03-2018 CDC59_RS19670 a6551cb1cbeb4d880fc89cf5a7bd2459 925 TIGRFAM TIGR03361 VI_Rhs_Vgr: type VI secretion system Vgr family protein 23 540 8.5E-100 T 29-03-2018 IPR017847 Type VI secretion system, RhsGE-associated Vgr family subset CDC59_RS19670 a6551cb1cbeb4d880fc89cf5a7bd2459 925 Pfam PF10106 Uncharacterized protein conserved in bacteria (DUF2345) 736 891 2.7E-40 T 29-03-2018 IPR018769 Domain of unknown function DUF2345, Vgr C-terminal CDC59_RS19670 a6551cb1cbeb4d880fc89cf5a7bd2459 925 SUPERFAMILY SSF69279 404 421 2.81E-19 T 29-03-2018 CDC59_RS19670 a6551cb1cbeb4d880fc89cf5a7bd2459 925 SUPERFAMILY SSF69279 232 364 2.81E-19 T 29-03-2018 CDC59_RS19670 a6551cb1cbeb4d880fc89cf5a7bd2459 925 Pfam PF05954 Phage late control gene D protein (GPD) 47 362 3.7E-80 T 29-03-2018 CDC59_RS19670 a6551cb1cbeb4d880fc89cf5a7bd2459 925 Pfam PF13296 Putative type VI secretion system Rhs element Vgr 593 696 2.2E-25 T 29-03-2018 IPR028244 Putative type VI secretion system, Rhs element associated Vgr domain CDC59_RS10150 b68d598d2a3c610de2a4a4f45f30b5b6 648 SUPERFAMILY SSF54534 263 373 4.12E-31 T 29-03-2018 CDC59_RS10150 b68d598d2a3c610de2a4a4f45f30b5b6 648 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 311 332 - T 29-03-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 CDC59_RS10150 b68d598d2a3c610de2a4a4f45f30b5b6 648 Gene3D G3DSA:1.10.4030.10 39 173 4.5E-24 T 29-03-2018 CDC59_RS10150 b68d598d2a3c610de2a4a4f45f30b5b6 648 Gene3D G3DSA:3.10.50.40 261 398 2.8E-40 T 29-03-2018 CDC59_RS10150 b68d598d2a3c610de2a4a4f45f30b5b6 648 Gene3D G3DSA:3.10.50.40 399 514 0.023 T 29-03-2018 CDC59_RS10150 b68d598d2a3c610de2a4a4f45f30b5b6 648 SUPERFAMILY SSF109998 41 170 1.45E-29 T 29-03-2018 IPR027304 Trigger factor/SurA domain CDC59_RS10150 b68d598d2a3c610de2a4a4f45f30b5b6 648 SUPERFAMILY SSF109998 204 244 1.45E-29 T 29-03-2018 IPR027304 Trigger factor/SurA domain CDC59_RS10150 b68d598d2a3c610de2a4a4f45f30b5b6 648 Pfam PF13616 PPIC-type PPIASE domain 267 374 2.0E-29 T 29-03-2018 CDC59_RS10150 b68d598d2a3c610de2a4a4f45f30b5b6 648 Pfam PF13624 SurA N-terminal domain 1 166 1.1E-44 T 29-03-2018 CDC59_RS23095 9318ae46834a5dc7a24f29887c846297 605 Pfam PF02203 Tar ligand binding domain homologue 1 172 1.6E-45 T 29-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 CDC59_RS23095 9318ae46834a5dc7a24f29887c846297 605 SMART SM00304 212 264 7.5E-11 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CDC59_RS23095 9318ae46834a5dc7a24f29887c846297 605 Gene3D G3DSA:1.10.287.950 324 516 4.5E-45 T 29-03-2018 CDC59_RS23095 9318ae46834a5dc7a24f29887c846297 605 SMART SM00283 265 512 5.6E-84 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CDC59_RS23095 9318ae46834a5dc7a24f29887c846297 605 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 440 469 2.8E-59 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS23095 9318ae46834a5dc7a24f29887c846297 605 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 286 315 2.8E-59 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS23095 9318ae46834a5dc7a24f29887c846297 605 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 392 421 2.8E-59 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS23095 9318ae46834a5dc7a24f29887c846297 605 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 363 390 2.8E-59 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS23095 9318ae46834a5dc7a24f29887c846297 605 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 61 76 2.8E-59 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS23095 9318ae46834a5dc7a24f29887c846297 605 Gene3D G3DSA:1.20.120.30 23 186 1.8E-29 T 29-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain CDC59_RS23095 9318ae46834a5dc7a24f29887c846297 605 Pfam PF00672 HAMP domain 212 261 3.7E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CDC59_RS23095 9318ae46834a5dc7a24f29887c846297 605 SUPERFAMILY SSF47170 48 141 3.27E-7 T 29-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 CDC59_RS23095 9318ae46834a5dc7a24f29887c846297 605 SUPERFAMILY SSF58104 232 514 6.67E-73 T 29-03-2018 CDC59_RS23095 9318ae46834a5dc7a24f29887c846297 605 Gene3D G3DSA:1.10.287.1060 231 323 0.0011 T 29-03-2018 CDC59_RS23095 9318ae46834a5dc7a24f29887c846297 605 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 324 480 4.3E-51 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CDC59_RS23255 c56a8083fa49b33ec484da09c1b72b7e 328 Pfam PF01609 Transposase DDE domain 138 312 1.8E-31 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS23255 c56a8083fa49b33ec484da09c1b72b7e 328 Pfam PF05598 Transposase domain (DUF772) 51 126 5.1E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS23925 a116b5f3bd31ec51a5f333dfca58c48b 462 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 227 242 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CDC59_RS23925 a116b5f3bd31ec51a5f333dfca58c48b 462 SUPERFAMILY SSF52540 141 381 8.16E-72 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS23925 a116b5f3bd31ec51a5f333dfca58c48b 462 SUPERFAMILY SSF46689 353 445 2.37E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS23925 a116b5f3bd31ec51a5f333dfca58c48b 462 Gene3D G3DSA:3.40.50.2300 1 149 8.8E-30 T 29-03-2018 CDC59_RS23925 a116b5f3bd31ec51a5f333dfca58c48b 462 Gene3D G3DSA:1.10.8.60 314 390 6.3E-23 T 29-03-2018 CDC59_RS23925 a116b5f3bd31ec51a5f333dfca58c48b 462 Gene3D G3DSA:1.10.10.60 401 447 2.2E-13 T 29-03-2018 CDC59_RS23925 a116b5f3bd31ec51a5f333dfca58c48b 462 Pfam PF00072 Response regulator receiver domain 4 112 1.5E-23 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS23925 a116b5f3bd31ec51a5f333dfca58c48b 462 Pfam PF00158 Sigma-54 interaction domain 142 307 6.1E-70 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CDC59_RS23925 a116b5f3bd31ec51a5f333dfca58c48b 462 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 427 447 1.4E-8 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CDC59_RS23925 a116b5f3bd31ec51a5f333dfca58c48b 462 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 410 427 1.4E-8 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CDC59_RS23925 a116b5f3bd31ec51a5f333dfca58c48b 462 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 353 362 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site CDC59_RS23925 a116b5f3bd31ec51a5f333dfca58c48b 462 Pfam PF02954 Bacterial regulatory protein, Fis family 404 444 9.0E-14 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CDC59_RS23925 a116b5f3bd31ec51a5f333dfca58c48b 462 SMART SM00382 161 305 4.1E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS23925 a116b5f3bd31ec51a5f333dfca58c48b 462 SMART SM00448 2 112 4.6E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS23925 a116b5f3bd31ec51a5f333dfca58c48b 462 Gene3D G3DSA:3.40.50.300 150 313 1.4E-29 T 29-03-2018 CDC59_RS23925 a116b5f3bd31ec51a5f333dfca58c48b 462 SUPERFAMILY SSF52172 1 186 1.57E-38 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS23830 12d6b0143b6470367960cc8e28c8e0fb 132 Gene3D G3DSA:3.30.429.10 1 65 6.0E-13 T 29-03-2018 CDC59_RS23830 12d6b0143b6470367960cc8e28c8e0fb 132 Gene3D G3DSA:3.30.429.10 67 131 3.7E-9 T 29-03-2018 CDC59_RS23830 12d6b0143b6470367960cc8e28c8e0fb 132 Pfam PF01361 Tautomerase enzyme 2 59 4.0E-7 T 29-03-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 CDC59_RS23830 12d6b0143b6470367960cc8e28c8e0fb 132 SUPERFAMILY SSF55331 2 127 2.15E-19 T 29-03-2018 IPR014347 Tautomerase/MIF superfamily CDC59_RS02140 da4eaaf25a92f554ea35a37aa87cd19d 143 SUPERFAMILY SSF54747 3 72 5.63E-30 T 29-03-2018 IPR020784 Ribosomal protein L11, N-terminal CDC59_RS02140 da4eaaf25a92f554ea35a37aa87cd19d 143 SUPERFAMILY SSF46906 68 141 5.76E-26 T 29-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CDC59_RS02140 da4eaaf25a92f554ea35a37aa87cd19d 143 Gene3D G3DSA:3.30.1550.10 3 72 2.7E-33 T 29-03-2018 IPR020784 Ribosomal protein L11, N-terminal CDC59_RS02140 da4eaaf25a92f554ea35a37aa87cd19d 143 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 74 2.0E-16 T 29-03-2018 CDC59_RS02140 da4eaaf25a92f554ea35a37aa87cd19d 143 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 141 1.1E-64 T 29-03-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS02140 da4eaaf25a92f554ea35a37aa87cd19d 143 SMART SM00649 9 141 5.7E-85 T 29-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 CDC59_RS02140 da4eaaf25a92f554ea35a37aa87cd19d 143 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 142 31.304 T 29-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 CDC59_RS02140 da4eaaf25a92f554ea35a37aa87cd19d 143 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 67 1.1E-28 T 29-03-2018 IPR020784 Ribosomal protein L11, N-terminal CDC59_RS02140 da4eaaf25a92f554ea35a37aa87cd19d 143 Gene3D G3DSA:1.10.10.250 73 141 6.4E-24 T 29-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CDC59_RS02140 da4eaaf25a92f554ea35a37aa87cd19d 143 ProSitePatterns PS00359 Ribosomal protein L11 signature. 127 142 - T 29-03-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS02140 da4eaaf25a92f554ea35a37aa87cd19d 143 Pfam PF00298 Ribosomal protein L11, RNA binding domain 72 140 2.3E-24 T 29-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CDC59_RS02305 562f1263335e8a70e8cd6696e50e64d3 131 SUPERFAMILY SSF56047 2 130 6.15E-48 T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS02305 562f1263335e8a70e8cd6696e50e64d3 131 Pfam PF00410 Ribosomal protein S8 5 130 3.1E-49 T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS02305 562f1263335e8a70e8cd6696e50e64d3 131 Gene3D G3DSA:3.30.1370.30 1 67 1.4E-26 T 29-03-2018 CDC59_RS02305 562f1263335e8a70e8cd6696e50e64d3 131 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 131 32.253 T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS02305 562f1263335e8a70e8cd6696e50e64d3 131 Gene3D G3DSA:3.30.1490.10 75 130 4.1E-21 T 29-03-2018 CDC59_RS02305 562f1263335e8a70e8cd6696e50e64d3 131 ProSitePatterns PS00053 Ribosomal protein S8 signature. 101 118 - T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS10430 9a51f780a00dd44a4d184738bb08f1f3 469 SUPERFAMILY SSF100950 132 293 1.72E-34 T 29-03-2018 CDC59_RS10430 9a51f780a00dd44a4d184738bb08f1f3 469 SUPERFAMILY SSF100950 61 86 1.72E-34 T 29-03-2018 CDC59_RS10430 9a51f780a00dd44a4d184738bb08f1f3 469 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 310 321 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CDC59_RS10430 9a51f780a00dd44a4d184738bb08f1f3 469 Gene3D G3DSA:1.10.1060.10 313 398 6.4E-13 T 29-03-2018 CDC59_RS10430 9a51f780a00dd44a4d184738bb08f1f3 469 Gene3D G3DSA:3.40.50.10420 132 285 6.3E-42 T 29-03-2018 CDC59_RS10430 9a51f780a00dd44a4d184738bb08f1f3 469 Gene3D G3DSA:3.40.50.10420 60 131 6.9E-5 T 29-03-2018 CDC59_RS10430 9a51f780a00dd44a4d184738bb08f1f3 469 Pfam PF11870 Domain of unknown function (DUF3390) 393 465 1.7E-13 T 29-03-2018 IPR024569 4Fe-4S binding protein, C-terminal CDC59_RS10430 9a51f780a00dd44a4d184738bb08f1f3 469 Pfam PF02589 LUD domain 68 292 8.0E-51 T 29-03-2018 IPR003741 LUD domain CDC59_RS10430 9a51f780a00dd44a4d184738bb08f1f3 469 TIGRFAM TIGR00273 TIGR00273: iron-sulfur cluster-binding protein 17 451 6.9E-138 T 29-03-2018 IPR004452 4Fe-4S binding protein GO:0019516 CDC59_RS10430 9a51f780a00dd44a4d184738bb08f1f3 469 SUPERFAMILY SSF54862 308 402 3.56E-14 T 29-03-2018 CDC59_RS10430 9a51f780a00dd44a4d184738bb08f1f3 469 Pfam PF13183 4Fe-4S dicluster domain 307 374 2.3E-8 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CDC59_RS10430 9a51f780a00dd44a4d184738bb08f1f3 469 Gene3D G3DSA:3.30.70.20 286 312 0.0048 T 29-03-2018 CDC59_RS04635 040a42e8be7718bc98f5dfd7c15b27de 376 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 1 203 39.293 T 29-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CDC59_RS04635 040a42e8be7718bc98f5dfd7c15b27de 376 PIRSF PIRSF001259 1 372 1.8E-116 T 29-03-2018 CDC59_RS04635 040a42e8be7718bc98f5dfd7c15b27de 376 SUPERFAMILY SSF142695 204 363 1.7E-42 T 29-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CDC59_RS04635 040a42e8be7718bc98f5dfd7c15b27de 376 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 7 198 3.1E-84 T 29-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CDC59_RS04635 040a42e8be7718bc98f5dfd7c15b27de 376 Gene3D G3DSA:3.90.870.10 1 212 2.8E-95 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CDC59_RS04635 040a42e8be7718bc98f5dfd7c15b27de 376 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 4 199 1.0E-75 T 29-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CDC59_RS04635 040a42e8be7718bc98f5dfd7c15b27de 376 Pfam PF00925 GTP cyclohydrolase II 210 361 1.1E-31 T 29-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CDC59_RS04635 040a42e8be7718bc98f5dfd7c15b27de 376 SUPERFAMILY SSF55821 3 202 8.01E-88 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CDC59_RS04455 99fad678c1457632b2e81b62fb5cab7d 266 Gene3D G3DSA:3.40.1130.10 49 217 4.1E-29 T 29-03-2018 CDC59_RS04455 99fad678c1457632b2e81b62fb5cab7d 266 SMART SM00563 87 199 1.9E-34 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CDC59_RS04455 99fad678c1457632b2e81b62fb5cab7d 266 SUPERFAMILY SSF69593 42 197 6.28E-26 T 29-03-2018 CDC59_RS04455 99fad678c1457632b2e81b62fb5cab7d 266 Pfam PF01553 Acyltransferase 85 195 1.5E-22 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CDC59_RS16640 b389d3a29ded7398adf18d392b71f7a0 736 TIGRFAM TIGR01646 vgr_GE: Rhs element Vgr protein 41 532 1.8E-130 T 29-03-2018 IPR006533 Type VI secretion system, RhsGE-associated Vgr protein CDC59_RS16640 b389d3a29ded7398adf18d392b71f7a0 736 Pfam PF05954 Phage late control gene D protein (GPD) 49 356 1.6E-65 T 29-03-2018 CDC59_RS16640 b389d3a29ded7398adf18d392b71f7a0 736 TIGRFAM TIGR03361 VI_Rhs_Vgr: type VI secretion system Vgr family protein 40 549 3.2E-150 T 29-03-2018 IPR017847 Type VI secretion system, RhsGE-associated Vgr family subset CDC59_RS16640 b389d3a29ded7398adf18d392b71f7a0 736 SUPERFAMILY SSF69255 391 478 2.17E-33 T 29-03-2018 CDC59_RS16640 b389d3a29ded7398adf18d392b71f7a0 736 SUPERFAMILY SSF69279 223 383 1.24E-15 T 29-03-2018 CDC59_RS16640 b389d3a29ded7398adf18d392b71f7a0 736 Gene3D G3DSA:2.40.50.230 396 478 9.0E-36 T 29-03-2018 IPR006531 Gp5 N-terminal CDC59_RS16640 b389d3a29ded7398adf18d392b71f7a0 736 SUPERFAMILY SSF69279 38 203 9.07E-42 T 29-03-2018 CDC59_RS16640 b389d3a29ded7398adf18d392b71f7a0 736 Gene3D G3DSA:3.55.50.10 117 208 8.2E-20 T 29-03-2018 CDC59_RS16640 b389d3a29ded7398adf18d392b71f7a0 736 SUPERFAMILY SSF69349 468 634 1.88E-50 T 29-03-2018 CDC59_RS16640 b389d3a29ded7398adf18d392b71f7a0 736 Pfam PF06715 Gp5 C-terminal repeat (3 copies) 587 610 3.4E-4 T 29-03-2018 IPR010609 Gp5, C-terminal CDC59_RS16640 b389d3a29ded7398adf18d392b71f7a0 736 Pfam PF06715 Gp5 C-terminal repeat (3 copies) 563 586 1.4E-4 T 29-03-2018 IPR010609 Gp5, C-terminal CDC59_RS06190 acec767b6f0e452e3a0922bacb170514 300 Pfam PF03466 LysR substrate binding domain 90 288 2.4E-19 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS06190 acec767b6f0e452e3a0922bacb170514 300 SUPERFAMILY SSF46785 2 112 2.87E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS06190 acec767b6f0e452e3a0922bacb170514 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 1.1E-15 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS06190 acec767b6f0e452e3a0922bacb170514 300 Gene3D G3DSA:3.40.190.10 181 259 1.2E-6 T 29-03-2018 CDC59_RS06190 acec767b6f0e452e3a0922bacb170514 300 Gene3D G3DSA:1.10.10.10 1 85 2.8E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS06190 acec767b6f0e452e3a0922bacb170514 300 SUPERFAMILY SSF53850 90 290 2.71E-24 T 29-03-2018 CDC59_RS06190 acec767b6f0e452e3a0922bacb170514 300 Gene3D G3DSA:3.40.190.10 90 180 2.0E-13 T 29-03-2018 CDC59_RS01210 98655ccef680758405f6532d13062b91 172 Gene3D G3DSA:3.40.30.10 24 164 5.7E-24 T 29-03-2018 CDC59_RS01210 98655ccef680758405f6532d13062b91 172 Pfam PF08534 Redoxin 31 158 2.9E-14 T 29-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 CDC59_RS01210 98655ccef680758405f6532d13062b91 172 SUPERFAMILY SSF52833 10 157 2.67E-26 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS03180 7e18daab5256fc0c142999aaad01cdcf 934 Pfam PF07516 SecA Wing and Scaffold domain 627 839 1.5E-63 T 29-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CDC59_RS03180 7e18daab5256fc0c142999aaad01cdcf 934 Pfam PF07517 SecA DEAD-like domain 6 405 7.2E-134 T 29-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CDC59_RS03180 7e18daab5256fc0c142999aaad01cdcf 934 Hamap MF_01382 Protein translocase subunit SecA [secA]. 5 842 19.915 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CDC59_RS03180 7e18daab5256fc0c142999aaad01cdcf 934 SUPERFAMILY SSF52540 421 628 8.7E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS03180 7e18daab5256fc0c142999aaad01cdcf 934 PRINTS PR00906 SecA protein signature 170 190 3.8E-69 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CDC59_RS03180 7e18daab5256fc0c142999aaad01cdcf 934 PRINTS PR00906 SecA protein signature 416 429 3.8E-69 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CDC59_RS03180 7e18daab5256fc0c142999aaad01cdcf 934 PRINTS PR00906 SecA protein signature 117 127 3.8E-69 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CDC59_RS03180 7e18daab5256fc0c142999aaad01cdcf 934 PRINTS PR00906 SecA protein signature 379 396 3.8E-69 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CDC59_RS03180 7e18daab5256fc0c142999aaad01cdcf 934 PRINTS PR00906 SecA protein signature 63 87 3.8E-69 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CDC59_RS03180 7e18daab5256fc0c142999aaad01cdcf 934 PRINTS PR00906 SecA protein signature 342 364 3.8E-69 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CDC59_RS03180 7e18daab5256fc0c142999aaad01cdcf 934 PRINTS PR00906 SecA protein signature 101 115 3.8E-69 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CDC59_RS03180 7e18daab5256fc0c142999aaad01cdcf 934 SUPERFAMILY SSF81767 230 371 2.88E-43 T 29-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CDC59_RS03180 7e18daab5256fc0c142999aaad01cdcf 934 Gene3D G3DSA:3.40.50.300 420 643 3.4E-54 T 29-03-2018 CDC59_RS03180 7e18daab5256fc0c142999aaad01cdcf 934 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 28 828 0.0 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CDC59_RS03180 7e18daab5256fc0c142999aaad01cdcf 934 Pfam PF02810 SEC-C motif 914 932 1.8E-10 T 29-03-2018 IPR004027 SEC-C motif CDC59_RS03180 7e18daab5256fc0c142999aaad01cdcf 934 Gene3D G3DSA:3.40.50.300 9 262 1.2E-54 T 29-03-2018 CDC59_RS03180 7e18daab5256fc0c142999aaad01cdcf 934 Gene3D G3DSA:3.40.50.300 308 419 8.2E-10 T 29-03-2018 CDC59_RS03180 7e18daab5256fc0c142999aaad01cdcf 934 Pfam PF01043 SecA preprotein cross-linking domain 233 361 7.6E-37 T 29-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CDC59_RS03180 7e18daab5256fc0c142999aaad01cdcf 934 SUPERFAMILY SSF81886 910 922 2.35E-77 T 29-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CDC59_RS03180 7e18daab5256fc0c142999aaad01cdcf 934 SUPERFAMILY SSF81886 632 850 2.35E-77 T 29-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CDC59_RS03180 7e18daab5256fc0c142999aaad01cdcf 934 ProSitePatterns PS01312 SecA family signature. 503 518 - T 29-03-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 CDC59_RS03180 7e18daab5256fc0c142999aaad01cdcf 934 SMART SM00958 228 361 3.1E-79 T 29-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CDC59_RS03180 7e18daab5256fc0c142999aaad01cdcf 934 Gene3D G3DSA:1.10.3060.10 644 740 3.1E-27 T 29-03-2018 CDC59_RS03180 7e18daab5256fc0c142999aaad01cdcf 934 Gene3D G3DSA:3.10.450.50 741 934 1.4E-48 T 29-03-2018 CDC59_RS03180 7e18daab5256fc0c142999aaad01cdcf 934 SUPERFAMILY SSF52540 371 418 1.76E-85 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS03180 7e18daab5256fc0c142999aaad01cdcf 934 SUPERFAMILY SSF52540 5 228 1.76E-85 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS03180 7e18daab5256fc0c142999aaad01cdcf 934 SMART SM00957 6 405 0.0 T 29-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CDC59_RS21865 614c886cabbf0fea0ec4d079cca24974 551 Pfam PF02366 Dolichyl-phosphate-mannose-protein mannosyltransferase 28 234 1.8E-16 T 29-03-2018 IPR003342 Glycosyl transferase family 39/83 GO:0000030|GO:0006493|GO:0016020 Reactome: R-HSA-5173105 CDC59_RS09145 08fcf2f8d4e078a184545200b8fe638f 275 Gene3D G3DSA:3.90.230.10 1 267 6.5E-83 T 29-03-2018 CDC59_RS09145 08fcf2f8d4e078a184545200b8fe638f 275 Hamap MF_01974 Methionine aminopeptidase [map]. 3 257 40.595 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CDC59_RS09145 08fcf2f8d4e078a184545200b8fe638f 275 PRINTS PR00599 Methionine aminopeptidase-1 signature 168 180 1.6E-14 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CDC59_RS09145 08fcf2f8d4e078a184545200b8fe638f 275 PRINTS PR00599 Methionine aminopeptidase-1 signature 199 211 1.6E-14 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CDC59_RS09145 08fcf2f8d4e078a184545200b8fe638f 275 PRINTS PR00599 Methionine aminopeptidase-1 signature 74 87 1.6E-14 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CDC59_RS09145 08fcf2f8d4e078a184545200b8fe638f 275 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 4 255 5.5E-93 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CDC59_RS09145 08fcf2f8d4e078a184545200b8fe638f 275 SUPERFAMILY SSF55920 5 256 4.84E-88 T 29-03-2018 IPR000994 Peptidase M24 CDC59_RS09145 08fcf2f8d4e078a184545200b8fe638f 275 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 174 192 - T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CDC59_RS09145 08fcf2f8d4e078a184545200b8fe638f 275 Pfam PF00557 Metallopeptidase family M24 13 248 1.3E-50 T 29-03-2018 IPR000994 Peptidase M24 CDC59_RS15385 703643e37e28f72de24c4b76a0427ec0 397 SUPERFAMILY SSF53335 23 378 1.71E-88 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS15385 703643e37e28f72de24c4b76a0427ec0 397 Pfam PF02636 Putative S-adenosyl-L-methionine-dependent methyltransferase 85 322 3.9E-46 T 29-03-2018 IPR003788 Protein arginine methyltransferase NDUFAF7 Reactome: R-HSA-6799198 CDC59_RS15385 703643e37e28f72de24c4b76a0427ec0 397 Gene3D G3DSA:3.40.50.150 84 324 3.7E-6 T 29-03-2018 CDC59_RS14485 5e6d5856553b3f6bd97e896b1130e005 156 Pfam PF00588 SpoU rRNA Methylase family 2 143 5.2E-32 T 29-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CDC59_RS14485 5e6d5856553b3f6bd97e896b1130e005 156 Gene3D G3DSA:3.40.1280.10 1 156 8.5E-38 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CDC59_RS14485 5e6d5856553b3f6bd97e896b1130e005 156 PIRSF PIRSF029256 1 156 2.8E-63 T 29-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CDC59_RS14485 5e6d5856553b3f6bd97e896b1130e005 156 TIGRFAM TIGR00185 tRNA_yibK_trmL: tRNA (cytidine(34)-2'-O)-methyltransferase 1 154 1.5E-58 T 29-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CDC59_RS14485 5e6d5856553b3f6bd97e896b1130e005 156 SUPERFAMILY SSF75217 1 153 5.76E-43 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases CDC59_RS14485 5e6d5856553b3f6bd97e896b1130e005 156 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 2 153 32.489 T 29-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CDC59_RS06450 28eec07ec118070de6158759420764e9 221 Gene3D G3DSA:3.40.50.300 22 63 1.2E-5 T 29-03-2018 CDC59_RS06450 28eec07ec118070de6158759420764e9 221 Gene3D G3DSA:3.40.50.300 96 201 2.0E-29 T 29-03-2018 CDC59_RS06450 28eec07ec118070de6158759420764e9 221 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 21 198 9.7E-70 T 29-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 CDC59_RS06450 28eec07ec118070de6158759420764e9 221 Pfam PF00625 Guanylate kinase 23 199 2.9E-46 T 29-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CDC59_RS06450 28eec07ec118070de6158759420764e9 221 SMART SM00072 19 201 1.5E-54 T 29-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CDC59_RS06450 28eec07ec118070de6158759420764e9 221 SUPERFAMILY SSF52540 18 204 1.57E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS06450 28eec07ec118070de6158759420764e9 221 ProSitePatterns PS00856 Guanylate kinase-like signature. 54 71 - T 29-03-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 CDC59_RS06450 28eec07ec118070de6158759420764e9 221 Gene3D G3DSA:3.30.63.10 64 95 3.4E-23 T 29-03-2018 CDC59_RS06450 28eec07ec118070de6158759420764e9 221 Hamap MF_00328 Guanylate kinase [gmk]. 18 201 35.138 T 29-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 CDC59_RS03130 a783bb9f7f28caaf158b56c44fe994da 365 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 14 150 2.5E-34 T 29-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CDC59_RS03130 a783bb9f7f28caaf158b56c44fe994da 365 SUPERFAMILY SSF53756 12 363 1.03E-121 T 29-03-2018 CDC59_RS03130 a783bb9f7f28caaf158b56c44fe994da 365 Gene3D G3DSA:3.40.50.2000 6 180 1.0E-39 T 29-03-2018 CDC59_RS03130 a783bb9f7f28caaf158b56c44fe994da 365 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 13 363 36.371 T 29-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CDC59_RS03130 a783bb9f7f28caaf158b56c44fe994da 365 Gene3D G3DSA:3.40.50.2000 181 357 1.4E-34 T 29-03-2018 CDC59_RS03130 a783bb9f7f28caaf158b56c44fe994da 365 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 11 358 9.9E-102 T 29-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CDC59_RS03130 a783bb9f7f28caaf158b56c44fe994da 365 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 190 354 5.4E-36 T 29-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CDC59_RS07235 6d62a368b716a612522965e9f06f020b 428 Pfam PF03454 MoeA C-terminal region (domain IV) 357 424 1.2E-19 T 29-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CDC59_RS07235 6d62a368b716a612522965e9f06f020b 428 SUPERFAMILY SSF53218 195 344 4.06E-44 T 29-03-2018 IPR001453 MoaB/Mog domain CDC59_RS07235 6d62a368b716a612522965e9f06f020b 428 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 195 333 1.7E-31 T 29-03-2018 IPR001453 MoaB/Mog domain CDC59_RS07235 6d62a368b716a612522965e9f06f020b 428 Gene3D G3DSA:3.40.980.10 181 348 3.4E-56 T 29-03-2018 IPR001453 MoaB/Mog domain CDC59_RS07235 6d62a368b716a612522965e9f06f020b 428 Gene3D G3DSA:3.90.105.10 147 180 1.5E-11 T 29-03-2018 CDC59_RS07235 6d62a368b716a612522965e9f06f020b 428 Gene3D G3DSA:3.90.105.10 39 76 4.0E-9 T 29-03-2018 CDC59_RS07235 6d62a368b716a612522965e9f06f020b 428 Pfam PF03453 MoeA N-terminal region (domain I and II) 20 185 1.4E-40 T 29-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CDC59_RS07235 6d62a368b716a612522965e9f06f020b 428 SUPERFAMILY SSF63867 349 427 1.16E-24 T 29-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CDC59_RS07235 6d62a368b716a612522965e9f06f020b 428 SUPERFAMILY SSF63882 18 193 3.53E-52 T 29-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CDC59_RS07235 6d62a368b716a612522965e9f06f020b 428 Pfam PF00994 Probable molybdopterin binding domain 200 337 5.5E-30 T 29-03-2018 IPR001453 MoaB/Mog domain CDC59_RS07235 6d62a368b716a612522965e9f06f020b 428 Gene3D G3DSA:2.170.190.11 77 146 2.9E-24 T 29-03-2018 CDC59_RS07235 6d62a368b716a612522965e9f06f020b 428 SMART SM00852 198 339 4.2E-45 T 29-03-2018 IPR001453 MoaB/Mog domain CDC59_RS07235 6d62a368b716a612522965e9f06f020b 428 Gene3D G3DSA:2.40.340.10 351 427 3.8E-22 T 29-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CDC59_RS20925 8b8cda6b67e8af961e6f89808ccd602d 2073 Gene3D G3DSA:1.10.1200.10 1957 2053 4.9E-12 T 29-03-2018 CDC59_RS20925 8b8cda6b67e8af961e6f89808ccd602d 2073 SUPERFAMILY SSF53335 1185 1300 1.13E-13 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS20925 8b8cda6b67e8af961e6f89808ccd602d 2073 SUPERFAMILY SSF47336 25 105 1.02E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS20925 8b8cda6b67e8af961e6f89808ccd602d 2073 Gene3D G3DSA:1.10.1200.10 6 95 3.0E-11 T 29-03-2018 CDC59_RS20925 8b8cda6b67e8af961e6f89808ccd602d 2073 Pfam PF00668 Condensation domain 149 466 1.5E-22 T 29-03-2018 IPR001242 Condensation domain CDC59_RS20925 8b8cda6b67e8af961e6f89808ccd602d 2073 Pfam PF00668 Condensation domain 1539 1929 3.3E-31 T 29-03-2018 IPR001242 Condensation domain CDC59_RS20925 8b8cda6b67e8af961e6f89808ccd602d 2073 SUPERFAMILY SSF47336 1424 1494 7.07E-16 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS20925 8b8cda6b67e8af961e6f89808ccd602d 2073 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 593 991 4.8E-117 T 29-03-2018 IPR010071 Amino acid adenylation domain CDC59_RS20925 8b8cda6b67e8af961e6f89808ccd602d 2073 SUPERFAMILY SSF52777 295 541 1.33E-39 T 29-03-2018 CDC59_RS20925 8b8cda6b67e8af961e6f89808ccd602d 2073 ProSitePatterns PS00455 Putative AMP-binding domain signature. 712 723 - T 29-03-2018 IPR020845 AMP-binding, conserved site CDC59_RS20925 8b8cda6b67e8af961e6f89808ccd602d 2073 Gene3D G3DSA:3.30.559.10 96 311 1.3E-22 T 29-03-2018 CDC59_RS20925 8b8cda6b67e8af961e6f89808ccd602d 2073 SUPERFAMILY SSF52777 117 289 2.22E-22 T 29-03-2018 CDC59_RS20925 8b8cda6b67e8af961e6f89808ccd602d 2073 Gene3D G3DSA:3.30.559.10 1500 1717 1.4E-23 T 29-03-2018 CDC59_RS20925 8b8cda6b67e8af961e6f89808ccd602d 2073 SUPERFAMILY SSF47336 1973 2050 6.02E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS20925 8b8cda6b67e8af961e6f89808ccd602d 2073 Pfam PF00550 Phosphopantetheine attachment site 1978 2040 4.3E-6 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS20925 8b8cda6b67e8af961e6f89808ccd602d 2073 Pfam PF00550 Phosphopantetheine attachment site 1432 1493 3.2E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS20925 8b8cda6b67e8af961e6f89808ccd602d 2073 Pfam PF00550 Phosphopantetheine attachment site 25 86 2.2E-8 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS20925 8b8cda6b67e8af961e6f89808ccd602d 2073 SMART SM00823 Phosphopantetheine attachment site 1976 2044 2.6E-6 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CDC59_RS20925 8b8cda6b67e8af961e6f89808ccd602d 2073 SMART SM00823 Phosphopantetheine attachment site 1427 1498 0.0045 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CDC59_RS20925 8b8cda6b67e8af961e6f89808ccd602d 2073 SMART SM00823 Phosphopantetheine attachment site 23 76 0.5 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CDC59_RS20925 8b8cda6b67e8af961e6f89808ccd602d 2073 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1454 1469 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CDC59_RS20925 8b8cda6b67e8af961e6f89808ccd602d 2073 Gene3D G3DSA:1.10.1200.10 1434 1499 7.8E-18 T 29-03-2018 CDC59_RS20925 8b8cda6b67e8af961e6f89808ccd602d 2073 Gene3D G3DSA:3.40.50.980 690 885 4.9E-51 T 29-03-2018 CDC59_RS20925 8b8cda6b67e8af961e6f89808ccd602d 2073 SUPERFAMILY SSF52777 1690 1933 3.11E-42 T 29-03-2018 CDC59_RS20925 8b8cda6b67e8af961e6f89808ccd602d 2073 Gene3D G3DSA:2.30.38.10 886 959 3.4E-24 T 29-03-2018 CDC59_RS20925 8b8cda6b67e8af961e6f89808ccd602d 2073 SUPERFAMILY SSF56801 1363 1443 1.24E-141 T 29-03-2018 CDC59_RS20925 8b8cda6b67e8af961e6f89808ccd602d 2073 SUPERFAMILY SSF56801 539 1021 1.24E-141 T 29-03-2018 CDC59_RS20925 8b8cda6b67e8af961e6f89808ccd602d 2073 Gene3D G3DSA:3.40.50.980 564 684 2.4E-28 T 29-03-2018 CDC59_RS20925 8b8cda6b67e8af961e6f89808ccd602d 2073 Gene3D G3DSA:3.30.300.30 964 1433 4.3E-32 T 29-03-2018 CDC59_RS20925 8b8cda6b67e8af961e6f89808ccd602d 2073 SUPERFAMILY SSF52777 1515 1701 3.78E-26 T 29-03-2018 CDC59_RS20925 8b8cda6b67e8af961e6f89808ccd602d 2073 Pfam PF00501 AMP-binding enzyme 572 968 4.6E-96 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CDC59_RS16310 e344cb0251c27b64fbf4b4ac56b7a978 434 SUPERFAMILY SSF103473 10 421 1.18E-58 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS16310 e344cb0251c27b64fbf4b4ac56b7a978 434 Gene3D G3DSA:1.20.1250.20 227 430 7.8E-24 T 29-03-2018 CDC59_RS16310 e344cb0251c27b64fbf4b4ac56b7a978 434 Pfam PF07690 Major Facilitator Superfamily 22 348 4.3E-30 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDC59_RS16310 e344cb0251c27b64fbf4b4ac56b7a978 434 Gene3D G3DSA:1.20.1250.20 5 211 5.4E-26 T 29-03-2018 CDC59_RS08420 548ce01c0650e7604da9a91ca80b7dd3 503 Gene3D G3DSA:3.40.50.2300 2 141 9.2E-32 T 29-03-2018 CDC59_RS08420 548ce01c0650e7604da9a91ca80b7dd3 503 Gene3D G3DSA:1.10.8.60 309 379 7.1E-22 T 29-03-2018 CDC59_RS08420 548ce01c0650e7604da9a91ca80b7dd3 503 Pfam PF02954 Bacterial regulatory protein, Fis family 461 500 2.3E-10 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CDC59_RS08420 548ce01c0650e7604da9a91ca80b7dd3 503 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 349 358 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site CDC59_RS08420 548ce01c0650e7604da9a91ca80b7dd3 503 SMART SM00382 156 303 3.1E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS08420 548ce01c0650e7604da9a91ca80b7dd3 503 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 222 237 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CDC59_RS08420 548ce01c0650e7604da9a91ca80b7dd3 503 TIGRFAM TIGR01818 ntrC: nitrogen regulation protein NR(I) 4 387 4.9E-192 T 29-03-2018 IPR010114 Signal transduction response regulator, nitrogen regulation NR(I) GO:0000156|GO:0000160|GO:0003677|GO:0005524|GO:0006808 CDC59_RS08420 548ce01c0650e7604da9a91ca80b7dd3 503 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 160 173 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CDC59_RS08420 548ce01c0650e7604da9a91ca80b7dd3 503 Pfam PF00158 Sigma-54 interaction domain 136 302 4.4E-69 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CDC59_RS08420 548ce01c0650e7604da9a91ca80b7dd3 503 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 466 483 2.5E-7 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CDC59_RS08420 548ce01c0650e7604da9a91ca80b7dd3 503 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 483 503 2.5E-7 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CDC59_RS08420 548ce01c0650e7604da9a91ca80b7dd3 503 SUPERFAMILY SSF52540 135 378 3.0E-73 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS08420 548ce01c0650e7604da9a91ca80b7dd3 503 SUPERFAMILY SSF52172 2 181 2.56E-41 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS08420 548ce01c0650e7604da9a91ca80b7dd3 503 SUPERFAMILY SSF46689 427 502 5.38E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS08420 548ce01c0650e7604da9a91ca80b7dd3 503 Pfam PF00072 Response regulator receiver domain 4 113 6.5E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS08420 548ce01c0650e7604da9a91ca80b7dd3 503 Gene3D G3DSA:1.10.10.60 380 503 4.8E-13 T 29-03-2018 CDC59_RS08420 548ce01c0650e7604da9a91ca80b7dd3 503 Gene3D G3DSA:3.40.50.300 142 308 1.7E-29 T 29-03-2018 CDC59_RS08420 548ce01c0650e7604da9a91ca80b7dd3 503 SMART SM00448 2 113 7.3E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS08560 0562ab9664122e0db40ca2c70aa18ecf 491 Gene3D G3DSA:3.30.300.20 201 278 3.1E-29 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CDC59_RS08560 0562ab9664122e0db40ca2c70aa18ecf 491 SUPERFAMILY SSF54814 281 343 3.34E-15 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CDC59_RS08560 0562ab9664122e0db40ca2c70aa18ecf 491 SMART SM00316 136 202 1.4E-9 T 29-03-2018 IPR022967 RNA-binding domain, S1 CDC59_RS08560 0562ab9664122e0db40ca2c70aa18ecf 491 SUPERFAMILY SSF47794 429 490 1.22E-14 T 29-03-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 CDC59_RS08560 0562ab9664122e0db40ca2c70aa18ecf 491 Gene3D G3DSA:3.30.300.20 280 350 6.6E-14 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CDC59_RS08560 0562ab9664122e0db40ca2c70aa18ecf 491 SUPERFAMILY SSF69705 1 129 1.31E-39 T 29-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CDC59_RS08560 0562ab9664122e0db40ca2c70aa18ecf 491 Gene3D G3DSA:3.30.1480.10 1 132 6.4E-44 T 29-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CDC59_RS08560 0562ab9664122e0db40ca2c70aa18ecf 491 Gene3D G3DSA:1.10.150.20 351 430 6.9E-12 T 29-03-2018 CDC59_RS08560 0562ab9664122e0db40ca2c70aa18ecf 491 Gene3D G3DSA:2.40.50.140 139 200 9.9E-14 T 29-03-2018 CDC59_RS08560 0562ab9664122e0db40ca2c70aa18ecf 491 SUPERFAMILY SSF54814 202 280 4.38E-27 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CDC59_RS08560 0562ab9664122e0db40ca2c70aa18ecf 491 SMART SM00322 303 379 0.0023 T 29-03-2018 IPR004087 K Homology domain GO:0003676 CDC59_RS08560 0562ab9664122e0db40ca2c70aa18ecf 491 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 412 29.184 T 29-03-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 CDC59_RS08560 0562ab9664122e0db40ca2c70aa18ecf 491 SUPERFAMILY SSF50249 136 201 2.11E-16 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDC59_RS08560 0562ab9664122e0db40ca2c70aa18ecf 491 Pfam PF08529 NusA N-terminal domain 5 127 6.4E-37 T 29-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CDC59_RS08560 0562ab9664122e0db40ca2c70aa18ecf 491 Pfam PF13184 NusA-like KH domain 232 299 1.4E-23 T 29-03-2018 IPR025249 KH domain, NusA-like GO:0003723 CDC59_RS08560 0562ab9664122e0db40ca2c70aa18ecf 491 Pfam PF14520 Helix-hairpin-helix domain 432 487 5.3E-10 T 29-03-2018 CDC59_RS08560 0562ab9664122e0db40ca2c70aa18ecf 491 Gene3D G3DSA:1.10.150.20 431 491 3.4E-18 T 29-03-2018 CDC59_RS08560 0562ab9664122e0db40ca2c70aa18ecf 491 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 6 342 2.3E-122 T 29-03-2018 IPR010213 Transcription termination factor NusA GO:0003723 CDC59_RS08560 0562ab9664122e0db40ca2c70aa18ecf 491 SUPERFAMILY SSF47794 358 418 2.83E-16 T 29-03-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 CDC59_RS08560 0562ab9664122e0db40ca2c70aa18ecf 491 Pfam PF00575 S1 RNA binding domain 139 198 1.6E-7 T 29-03-2018 IPR003029 S1 domain GO:0003676 CDC59_RS08560 0562ab9664122e0db40ca2c70aa18ecf 491 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 367 415 2.3E-19 T 29-03-2018 IPR010214 Transcription termination factor NusA, C-terminal duplication CDC59_RS08560 0562ab9664122e0db40ca2c70aa18ecf 491 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 443 489 4.2E-15 T 29-03-2018 IPR010214 Transcription termination factor NusA, C-terminal duplication CDC59_RS21750 cdbec8ca35743f52871a1df76b7ad015 526 SUPERFAMILY SSF54631 295 432 1.21E-20 T 29-03-2018 CDC59_RS21750 cdbec8ca35743f52871a1df76b7ad015 526 Gene3D G3DSA:3.30.465.10 433 517 4.5E-17 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CDC59_RS21750 cdbec8ca35743f52871a1df76b7ad015 526 Pfam PF03471 Transporter associated domain 437 516 7.9E-16 T 29-03-2018 IPR005170 Transporter-associated domain CDC59_RS21750 cdbec8ca35743f52871a1df76b7ad015 526 SMART SM01091 436 517 1.5E-15 T 29-03-2018 IPR005170 Transporter-associated domain CDC59_RS21750 cdbec8ca35743f52871a1df76b7ad015 526 Pfam PF03741 Integral membrane protein TerC family 14 203 2.1E-48 T 29-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 CDC59_RS21750 cdbec8ca35743f52871a1df76b7ad015 526 Gene3D G3DSA:3.10.580.10 285 432 9.9E-22 T 29-03-2018 CDC59_RS21750 cdbec8ca35743f52871a1df76b7ad015 526 SUPERFAMILY SSF56176 435 523 1.45E-16 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CDC59_RS14285 90cb55c2a515ac1434761e929dee9f95 642 Gene3D G3DSA:1.25.40.10 271 329 1.3E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS14285 90cb55c2a515ac1434761e929dee9f95 642 Gene3D G3DSA:1.25.40.10 384 450 0.016 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS14285 90cb55c2a515ac1434761e929dee9f95 642 SUPERFAMILY SSF48452 226 435 6.15E-16 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS14285 90cb55c2a515ac1434761e929dee9f95 642 Gene3D G3DSA:1.25.40.10 455 545 2.1E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS14285 90cb55c2a515ac1434761e929dee9f95 642 Gene3D G3DSA:1.25.40.10 546 633 8.8E-15 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS14285 90cb55c2a515ac1434761e929dee9f95 642 SMART SM00028 294 327 15.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CDC59_RS14285 90cb55c2a515ac1434761e929dee9f95 642 SMART SM00028 519 553 50.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CDC59_RS14285 90cb55c2a515ac1434761e929dee9f95 642 SMART SM00028 587 620 110.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CDC59_RS14285 90cb55c2a515ac1434761e929dee9f95 642 SMART SM00028 485 518 47.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CDC59_RS14285 90cb55c2a515ac1434761e929dee9f95 642 SMART SM00028 227 260 88.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CDC59_RS14285 90cb55c2a515ac1434761e929dee9f95 642 SMART SM00028 328 361 190.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CDC59_RS14285 90cb55c2a515ac1434761e929dee9f95 642 Gene3D G3DSA:1.25.40.10 98 198 0.2 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS14285 90cb55c2a515ac1434761e929dee9f95 642 Pfam PF13432 Tetratricopeptide repeat 531 587 1.9E-4 T 29-03-2018 CDC59_RS14285 90cb55c2a515ac1434761e929dee9f95 642 Pfam PF13432 Tetratricopeptide repeat 298 362 8.2E-7 T 29-03-2018 CDC59_RS14285 90cb55c2a515ac1434761e929dee9f95 642 Gene3D G3DSA:1.25.40.10 199 270 2.4E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS14285 90cb55c2a515ac1434761e929dee9f95 642 Gene3D G3DSA:1.25.40.10 330 383 4.5E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS14285 90cb55c2a515ac1434761e929dee9f95 642 SUPERFAMILY SSF48452 461 621 1.44E-20 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS22770 7bcfe4d6ed492f17052f076f01f753b2 489 SUPERFAMILY SSF55347 177 487 9.48E-114 T 29-03-2018 CDC59_RS22770 7bcfe4d6ed492f17052f076f01f753b2 489 Gene3D G3DSA:3.30.360.10 189 488 4.7E-126 T 29-03-2018 CDC59_RS22770 7bcfe4d6ed492f17052f076f01f753b2 489 PIRSF PIRSF000110 1 489 3.0E-163 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CDC59_RS22770 7bcfe4d6ed492f17052f076f01f753b2 489 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 9 187 3.2E-50 T 29-03-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CDC59_RS22770 7bcfe4d6ed492f17052f076f01f753b2 489 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 5 487 76.939 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CDC59_RS22770 7bcfe4d6ed492f17052f076f01f753b2 489 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 189 486 8.2E-113 T 29-03-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CDC59_RS22770 7bcfe4d6ed492f17052f076f01f753b2 489 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 177 183 - T 29-03-2018 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CDC59_RS22770 7bcfe4d6ed492f17052f076f01f753b2 489 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 6 487 9.6E-166 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CDC59_RS22770 7bcfe4d6ed492f17052f076f01f753b2 489 SUPERFAMILY SSF51735 3 190 4.33E-50 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS22770 7bcfe4d6ed492f17052f076f01f753b2 489 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 143 156 1.6E-46 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CDC59_RS22770 7bcfe4d6ed492f17052f076f01f753b2 489 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 219 236 1.6E-46 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CDC59_RS22770 7bcfe4d6ed492f17052f076f01f753b2 489 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 328 354 1.6E-46 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CDC59_RS22770 7bcfe4d6ed492f17052f076f01f753b2 489 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 237 253 1.6E-46 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CDC59_RS22770 7bcfe4d6ed492f17052f076f01f753b2 489 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 167 195 1.6E-46 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CDC59_RS22770 7bcfe4d6ed492f17052f076f01f753b2 489 Gene3D G3DSA:3.40.50.720 3 188 1.4E-53 T 29-03-2018 CDC59_RS08840 6e5a3aa08f37ae393af6f5e9bd933a37 288 Pfam PF00005 ABC transporter 40 173 6.4E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS08840 6e5a3aa08f37ae393af6f5e9bd933a37 288 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS08840 6e5a3aa08f37ae393af6f5e9bd933a37 288 Gene3D G3DSA:3.40.50.300 21 231 1.9E-60 T 29-03-2018 CDC59_RS08840 6e5a3aa08f37ae393af6f5e9bd933a37 288 SUPERFAMILY SSF52540 25 231 4.31E-66 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS08840 6e5a3aa08f37ae393af6f5e9bd933a37 288 SMART SM00382 49 223 7.4E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS01405 208c2d148e9482c8842a645d1b23171f 2513 SMART SM00823 Phosphopantetheine attachment site 526 595 0.001 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CDC59_RS01405 208c2d148e9482c8842a645d1b23171f 2513 SMART SM00823 Phosphopantetheine attachment site 1593 1662 2.9E-6 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CDC59_RS01405 208c2d148e9482c8842a645d1b23171f 2513 Gene3D G3DSA:3.30.559.10 600 796 6.0E-38 T 29-03-2018 CDC59_RS01405 208c2d148e9482c8842a645d1b23171f 2513 Pfam PF13193 AMP-binding enzyme C-terminal domain 429 501 9.1E-13 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CDC59_RS01405 208c2d148e9482c8842a645d1b23171f 2513 Pfam PF13193 AMP-binding enzyme C-terminal domain 1493 1568 1.4E-13 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CDC59_RS01405 208c2d148e9482c8842a645d1b23171f 2513 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2311 2322 - T 29-03-2018 IPR020845 AMP-binding, conserved site CDC59_RS01405 208c2d148e9482c8842a645d1b23171f 2513 Gene3D G3DSA:3.40.50.980 2233 2316 2.6E-23 T 29-03-2018 CDC59_RS01405 208c2d148e9482c8842a645d1b23171f 2513 Gene3D G3DSA:3.40.50.980 22 175 3.7E-49 T 29-03-2018 CDC59_RS01405 208c2d148e9482c8842a645d1b23171f 2513 Gene3D G3DSA:3.40.50.980 1081 1234 7.7E-49 T 29-03-2018 CDC59_RS01405 208c2d148e9482c8842a645d1b23171f 2513 Gene3D G3DSA:3.30.300.30 413 531 1.9E-37 T 29-03-2018 CDC59_RS01405 208c2d148e9482c8842a645d1b23171f 2513 Gene3D G3DSA:3.30.300.30 1480 1598 5.2E-41 T 29-03-2018 CDC59_RS01405 208c2d148e9482c8842a645d1b23171f 2513 SUPERFAMILY SSF56801 1049 1600 9.94E-157 T 29-03-2018 CDC59_RS01405 208c2d148e9482c8842a645d1b23171f 2513 SUPERFAMILY SSF47336 1587 1658 1.57E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS01405 208c2d148e9482c8842a645d1b23171f 2513 ProSitePatterns PS00455 Putative AMP-binding domain signature. 170 181 - T 29-03-2018 IPR020845 AMP-binding, conserved site CDC59_RS01405 208c2d148e9482c8842a645d1b23171f 2513 SUPERFAMILY SSF56801 2232 2489 5.49E-60 T 29-03-2018 CDC59_RS01405 208c2d148e9482c8842a645d1b23171f 2513 Gene3D G3DSA:2.30.38.10 328 408 8.0E-25 T 29-03-2018 CDC59_RS01405 208c2d148e9482c8842a645d1b23171f 2513 Gene3D G3DSA:2.30.38.10 1394 1475 4.5E-23 T 29-03-2018 CDC59_RS01405 208c2d148e9482c8842a645d1b23171f 2513 Gene3D G3DSA:3.30.559.10 1661 1889 2.0E-43 T 29-03-2018 CDC59_RS01405 208c2d148e9482c8842a645d1b23171f 2513 SUPERFAMILY SSF52777 1682 1859 8.34E-48 T 29-03-2018 CDC59_RS01405 208c2d148e9482c8842a645d1b23171f 2513 SUPERFAMILY SSF52777 1873 2141 7.0E-59 T 29-03-2018 CDC59_RS01405 208c2d148e9482c8842a645d1b23171f 2513 Gene3D G3DSA:1.10.1200.10 532 598 1.3E-22 T 29-03-2018 CDC59_RS01405 208c2d148e9482c8842a645d1b23171f 2513 Gene3D G3DSA:1.10.1200.10 1599 1660 2.8E-24 T 29-03-2018 CDC59_RS01405 208c2d148e9482c8842a645d1b23171f 2513 Gene3D G3DSA:3.40.50.980 2145 2232 8.0E-31 T 29-03-2018 CDC59_RS01405 208c2d148e9482c8842a645d1b23171f 2513 SUPERFAMILY SSF47336 518 591 3.93E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS01405 208c2d148e9482c8842a645d1b23171f 2513 Pfam PF00668 Condensation domain 1679 2135 5.0E-88 T 29-03-2018 IPR001242 Condensation domain CDC59_RS01405 208c2d148e9482c8842a645d1b23171f 2513 Pfam PF00668 Condensation domain 613 1070 3.0E-83 T 29-03-2018 IPR001242 Condensation domain CDC59_RS01405 208c2d148e9482c8842a645d1b23171f 2513 Pfam PF00550 Phosphopantetheine attachment site 1595 1658 3.5E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS01405 208c2d148e9482c8842a645d1b23171f 2513 Pfam PF00550 Phosphopantetheine attachment site 529 591 1.1E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS01405 208c2d148e9482c8842a645d1b23171f 2513 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 51 442 1.2E-129 T 29-03-2018 IPR010071 Amino acid adenylation domain CDC59_RS01405 208c2d148e9482c8842a645d1b23171f 2513 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1110 1509 2.1E-129 T 29-03-2018 IPR010071 Amino acid adenylation domain CDC59_RS01405 208c2d148e9482c8842a645d1b23171f 2513 SUPERFAMILY SSF56801 2114 2232 3.27E-33 T 29-03-2018 CDC59_RS01405 208c2d148e9482c8842a645d1b23171f 2513 SUPERFAMILY SSF52777 807 1076 8.45E-61 T 29-03-2018 CDC59_RS01405 208c2d148e9482c8842a645d1b23171f 2513 ProSitePatterns PS00012 Phosphopantetheine attachment site. 550 565 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CDC59_RS01405 208c2d148e9482c8842a645d1b23171f 2513 Pfam PF00501 AMP-binding enzyme 30 418 6.3E-102 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CDC59_RS01405 208c2d148e9482c8842a645d1b23171f 2513 Pfam PF00501 AMP-binding enzyme 1089 1485 3.6E-98 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CDC59_RS01405 208c2d148e9482c8842a645d1b23171f 2513 Pfam PF00501 AMP-binding enzyme 2232 2488 1.4E-47 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CDC59_RS01405 208c2d148e9482c8842a645d1b23171f 2513 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1229 1240 - T 29-03-2018 IPR020845 AMP-binding, conserved site CDC59_RS01405 208c2d148e9482c8842a645d1b23171f 2513 Gene3D G3DSA:3.40.50.980 176 327 5.1E-34 T 29-03-2018 CDC59_RS01405 208c2d148e9482c8842a645d1b23171f 2513 Gene3D G3DSA:3.40.50.980 1235 1389 2.1E-33 T 29-03-2018 CDC59_RS01405 208c2d148e9482c8842a645d1b23171f 2513 Gene3D G3DSA:3.40.50.980 2317 2468 2.8E-34 T 29-03-2018 CDC59_RS01405 208c2d148e9482c8842a645d1b23171f 2513 SUPERFAMILY SSF52777 618 794 3.67E-47 T 29-03-2018 CDC59_RS01405 208c2d148e9482c8842a645d1b23171f 2513 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1617 1632 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CDC59_RS01405 208c2d148e9482c8842a645d1b23171f 2513 SUPERFAMILY SSF56801 20 539 3.14E-159 T 29-03-2018 CDC59_RS03215 b08fd8a96e4f0587ba1c64be4d60df2c 293 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 24 129 6.6E-36 T 29-03-2018 IPR010627 Peptidase A24A, N-terminal CDC59_RS03215 b08fd8a96e4f0587ba1c64be4d60df2c 293 Pfam PF01478 Type IV leader peptidase family 140 247 5.6E-26 T 29-03-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 CDC59_RS03215 b08fd8a96e4f0587ba1c64be4d60df2c 293 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 216 227 9.9E-27 T 29-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial CDC59_RS03215 b08fd8a96e4f0587ba1c64be4d60df2c 293 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 148 165 9.9E-27 T 29-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial CDC59_RS03215 b08fd8a96e4f0587ba1c64be4d60df2c 293 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 228 243 9.9E-27 T 29-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial CDC59_RS03215 b08fd8a96e4f0587ba1c64be4d60df2c 293 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 205 215 9.9E-27 T 29-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial CDC59_RS12945 4a23f4383ef5354799e1ddbaf86e6b62 222 Gene3D G3DSA:3.40.50.300 1 222 9.9E-63 T 29-03-2018 CDC59_RS12945 4a23f4383ef5354799e1ddbaf86e6b62 222 SUPERFAMILY SSF52540 1 184 8.46E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS12945 4a23f4383ef5354799e1ddbaf86e6b62 222 Pfam PF05191 Adenylate kinase, active site lid 123 158 6.2E-18 T 29-03-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 CDC59_RS12945 4a23f4383ef5354799e1ddbaf86e6b62 222 Pfam PF00406 Adenylate kinase 5 184 4.4E-57 T 29-03-2018 CDC59_RS12945 4a23f4383ef5354799e1ddbaf86e6b62 222 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 29-03-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CDC59_RS12945 4a23f4383ef5354799e1ddbaf86e6b62 222 Hamap MF_00235 Adenylate kinase [adk]. 1 221 52.211 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CDC59_RS12945 4a23f4383ef5354799e1ddbaf86e6b62 222 TIGRFAM TIGR01351 adk: adenylate kinase 2 184 3.3E-73 T 29-03-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 CDC59_RS12945 4a23f4383ef5354799e1ddbaf86e6b62 222 PRINTS PR00094 Adenylate kinase signature 156 171 8.6E-35 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CDC59_RS12945 4a23f4383ef5354799e1ddbaf86e6b62 222 PRINTS PR00094 Adenylate kinase signature 4 17 8.6E-35 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CDC59_RS12945 4a23f4383ef5354799e1ddbaf86e6b62 222 PRINTS PR00094 Adenylate kinase signature 32 46 8.6E-35 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CDC59_RS12945 4a23f4383ef5354799e1ddbaf86e6b62 222 PRINTS PR00094 Adenylate kinase signature 173 187 8.6E-35 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CDC59_RS12945 4a23f4383ef5354799e1ddbaf86e6b62 222 PRINTS PR00094 Adenylate kinase signature 81 97 8.6E-35 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CDC59_RS06555 867cca108b156741c28058a9be971ab3 117 TIGRFAM TIGR02962 hdxy_isourate: hydroxyisourate hydrolase 2 117 2.6E-40 T 29-03-2018 IPR014306 Hydroxyisourate hydrolase GO:0006144|GO:0033971 KEGG: 00230+3.5.2.17|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 CDC59_RS06555 867cca108b156741c28058a9be971ab3 117 ProSitePatterns PS00769 Transthyretin signature 2. 100 112 - T 29-03-2018 IPR023419 Transthyretin, conserved site Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 CDC59_RS06555 867cca108b156741c28058a9be971ab3 117 SUPERFAMILY SSF49472 1 117 4.45E-42 T 29-03-2018 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 CDC59_RS06555 867cca108b156741c28058a9be971ab3 117 PRINTS PR00189 Transthyretin signature 95 117 4.6E-6 T 29-03-2018 IPR000895 Transthyretin/hydroxyisourate hydrolase Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 CDC59_RS06555 867cca108b156741c28058a9be971ab3 117 PRINTS PR00189 Transthyretin signature 3 23 4.6E-6 T 29-03-2018 IPR000895 Transthyretin/hydroxyisourate hydrolase Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 CDC59_RS06555 867cca108b156741c28058a9be971ab3 117 ProSitePatterns PS00768 Transthyretin signature 1. 7 22 - T 29-03-2018 IPR023418 Transthyretin, thyroxine binding site Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 CDC59_RS06555 867cca108b156741c28058a9be971ab3 117 Pfam PF00576 HIUase/Transthyretin family 4 116 3.0E-35 T 29-03-2018 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 CDC59_RS06555 867cca108b156741c28058a9be971ab3 117 Gene3D G3DSA:2.60.40.180 1 117 3.5E-38 T 29-03-2018 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 CDC59_RS07460 332d3054e6a5c7476de34b3f1096b672 255 SMART SM00895 102 230 1.7E-27 T 29-03-2018 IPR011711 GntR, C-terminal CDC59_RS07460 332d3054e6a5c7476de34b3f1096b672 255 Gene3D G3DSA:1.20.120.530 85 246 2.4E-37 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CDC59_RS07460 332d3054e6a5c7476de34b3f1096b672 255 SMART SM00345 21 80 6.6E-26 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDC59_RS07460 332d3054e6a5c7476de34b3f1096b672 255 Gene3D G3DSA:1.10.10.10 9 81 1.7E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS07460 332d3054e6a5c7476de34b3f1096b672 255 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 54 7.8E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDC59_RS07460 332d3054e6a5c7476de34b3f1096b672 255 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 70 7.8E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDC59_RS07460 332d3054e6a5c7476de34b3f1096b672 255 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 80 4.6E-24 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDC59_RS07460 332d3054e6a5c7476de34b3f1096b672 255 Pfam PF07729 FCD domain 103 229 2.5E-29 T 29-03-2018 IPR011711 GntR, C-terminal CDC59_RS07460 332d3054e6a5c7476de34b3f1096b672 255 SUPERFAMILY SSF46785 13 84 3.62E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS07460 332d3054e6a5c7476de34b3f1096b672 255 SUPERFAMILY SSF48008 98 238 4.45E-31 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CDC59_RS10270 8b3876cf6f93492e2874611f27ee6e16 1147 SUPERFAMILY SSF52540 16 352 1.86E-97 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS10270 8b3876cf6f93492e2874611f27ee6e16 1147 SUPERFAMILY SSF52540 359 466 3.82E-25 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS10270 8b3876cf6f93492e2874611f27ee6e16 1147 Gene3D G3DSA:3.40.50.300 790 958 3.0E-26 T 29-03-2018 CDC59_RS10270 8b3876cf6f93492e2874611f27ee6e16 1147 SMART SM00490 828 912 7.8E-16 T 29-03-2018 IPR001650 Helicase, C-terminal CDC59_RS10270 8b3876cf6f93492e2874611f27ee6e16 1147 SMART SM00982 1010 1110 8.0E-48 T 29-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 CDC59_RS10270 8b3876cf6f93492e2874611f27ee6e16 1147 SUPERFAMILY SSF52540 525 785 7.25E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS10270 8b3876cf6f93492e2874611f27ee6e16 1147 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 44 1106 28.195 T 29-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 CDC59_RS10270 8b3876cf6f93492e2874611f27ee6e16 1147 Pfam PF00271 Helicase conserved C-terminal domain 807 911 4.5E-16 T 29-03-2018 IPR001650 Helicase, C-terminal CDC59_RS10270 8b3876cf6f93492e2874611f27ee6e16 1147 SUPERFAMILY SSF143517 996 1146 7.06E-39 T 29-03-2018 CDC59_RS10270 8b3876cf6f93492e2874611f27ee6e16 1147 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 157 1083 0.0 T 29-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 CDC59_RS10270 8b3876cf6f93492e2874611f27ee6e16 1147 Pfam PF02559 CarD-like/TRCF domain 482 577 1.3E-26 T 29-03-2018 IPR003711 CarD-like/TRCF domain CDC59_RS10270 8b3876cf6f93492e2874611f27ee6e16 1147 SMART SM00487 602 792 9.9E-31 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CDC59_RS10270 8b3876cf6f93492e2874611f27ee6e16 1147 SUPERFAMILY SSF141259 473 550 4.71E-23 T 29-03-2018 IPR003711 CarD-like/TRCF domain CDC59_RS10270 8b3876cf6f93492e2874611f27ee6e16 1147 Pfam PF03461 TRCF domain 1012 1102 9.1E-27 T 29-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 CDC59_RS10270 8b3876cf6f93492e2874611f27ee6e16 1147 Gene3D G3DSA:3.40.50.300 442 789 1.2E-37 T 29-03-2018 CDC59_RS10270 8b3876cf6f93492e2874611f27ee6e16 1147 Gene3D G3DSA:3.30.2060.10 139 183 0.0017 T 29-03-2018 CDC59_RS10270 8b3876cf6f93492e2874611f27ee6e16 1147 SUPERFAMILY SSF52540 785 992 6.55E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS10270 8b3876cf6f93492e2874611f27ee6e16 1147 Pfam PF00270 DEAD/DEAH box helicase 607 764 1.7E-16 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CDC59_RS10270 8b3876cf6f93492e2874611f27ee6e16 1147 SMART SM01058 481 578 4.1E-48 T 29-03-2018 IPR003711 CarD-like/TRCF domain CDC59_RS14915 8bdd6a9b56ce19a20e8a32391c01baeb 165 Pfam PF13411 MerR HTH family regulatory protein 29 97 2.1E-14 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CDC59_RS14915 8bdd6a9b56ce19a20e8a32391c01baeb 165 SUPERFAMILY SSF46955 29 147 6.96E-26 T 29-03-2018 IPR009061 Putative DNA-binding domain CDC59_RS14915 8bdd6a9b56ce19a20e8a32391c01baeb 165 Gene3D G3DSA:1.10.1660.10 85 164 1.9E-15 T 29-03-2018 CDC59_RS14915 8bdd6a9b56ce19a20e8a32391c01baeb 165 SMART SM00422 29 99 9.6E-16 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CDC59_RS14915 8bdd6a9b56ce19a20e8a32391c01baeb 165 Gene3D G3DSA:1.10.1660.10 25 84 2.7E-19 T 29-03-2018 CDC59_RS16850 dec99bcddc29509ed00b0d0403793c2f 1049 SUPERFAMILY SSF82693 38 132 4.45E-23 T 29-03-2018 CDC59_RS16850 dec99bcddc29509ed00b0d0403793c2f 1049 SUPERFAMILY SSF82714 183 272 8.5E-21 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS16850 dec99bcddc29509ed00b0d0403793c2f 1049 SUPERFAMILY SSF82866 805 1023 1.83E-43 T 29-03-2018 CDC59_RS16850 dec99bcddc29509ed00b0d0403793c2f 1049 SUPERFAMILY SSF82866 296 496 4.32E-47 T 29-03-2018 CDC59_RS16850 dec99bcddc29509ed00b0d0403793c2f 1049 PRINTS PR00702 Acriflavin resistance protein family signature 391 415 6.5E-100 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS16850 dec99bcddc29509ed00b0d0403793c2f 1049 PRINTS PR00702 Acriflavin resistance protein family signature 470 493 6.5E-100 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS16850 dec99bcddc29509ed00b0d0403793c2f 1049 PRINTS PR00702 Acriflavin resistance protein family signature 363 384 6.5E-100 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS16850 dec99bcddc29509ed00b0d0403793c2f 1049 PRINTS PR00702 Acriflavin resistance protein family signature 445 468 6.5E-100 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS16850 dec99bcddc29509ed00b0d0403793c2f 1049 PRINTS PR00702 Acriflavin resistance protein family signature 552 569 6.5E-100 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS16850 dec99bcddc29509ed00b0d0403793c2f 1049 PRINTS PR00702 Acriflavin resistance protein family signature 336 359 6.5E-100 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS16850 dec99bcddc29509ed00b0d0403793c2f 1049 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 6.5E-100 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS16850 dec99bcddc29509ed00b0d0403793c2f 1049 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 6.5E-100 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS16850 dec99bcddc29509ed00b0d0403793c2f 1049 PRINTS PR00702 Acriflavin resistance protein family signature 619 633 6.5E-100 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS16850 dec99bcddc29509ed00b0d0403793c2f 1049 SUPERFAMILY SSF82714 720 802 9.29E-19 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS16850 dec99bcddc29509ed00b0d0403793c2f 1049 Gene3D G3DSA:3.30.70.1440 668 764 5.1E-18 T 29-03-2018 CDC59_RS16850 dec99bcddc29509ed00b0d0403793c2f 1049 SUPERFAMILY SSF82693 565 665 5.18E-23 T 29-03-2018 CDC59_RS16850 dec99bcddc29509ed00b0d0403793c2f 1049 Gene3D G3DSA:3.30.2090.10 180 273 8.4E-18 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS16850 dec99bcddc29509ed00b0d0403793c2f 1049 Gene3D G3DSA:3.30.70.1430 567 667 1.1E-15 T 29-03-2018 CDC59_RS16850 dec99bcddc29509ed00b0d0403793c2f 1049 Gene3D G3DSA:1.20.1640.10 817 1022 1.5E-34 T 29-03-2018 CDC59_RS16850 dec99bcddc29509ed00b0d0403793c2f 1049 Gene3D G3DSA:1.20.1640.10 274 500 2.5E-43 T 29-03-2018 CDC59_RS16850 dec99bcddc29509ed00b0d0403793c2f 1049 Pfam PF00873 AcrB/AcrD/AcrF family 1 1021 0.0 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS16850 dec99bcddc29509ed00b0d0403793c2f 1049 SUPERFAMILY SSF82693 274 329 4.06E-25 T 29-03-2018 CDC59_RS16850 dec99bcddc29509ed00b0d0403793c2f 1049 SUPERFAMILY SSF82693 135 182 4.06E-25 T 29-03-2018 CDC59_RS16850 dec99bcddc29509ed00b0d0403793c2f 1049 Gene3D G3DSA:3.30.70.1430 38 140 4.8E-25 T 29-03-2018 CDC59_RS16850 dec99bcddc29509ed00b0d0403793c2f 1049 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 1 1025 0.0 T 29-03-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 CDC59_RS23960 67237a43dd381f436a394da0139dd52b 797 Gene3D G3DSA:3.30.450.20 271 396 4.3E-18 T 29-03-2018 CDC59_RS23960 67237a43dd381f436a394da0139dd52b 797 SUPERFAMILY SSF55874 474 642 2.62E-42 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS23960 67237a43dd381f436a394da0139dd52b 797 SMART SM00448 668 791 5.2E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS23960 67237a43dd381f436a394da0139dd52b 797 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 531 643 5.6E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS23960 67237a43dd381f436a394da0139dd52b 797 Gene3D G3DSA:3.30.565.10 480 644 3.5E-42 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS23960 67237a43dd381f436a394da0139dd52b 797 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 143 267 1.0E-14 T 29-03-2018 IPR000014 PAS domain CDC59_RS23960 67237a43dd381f436a394da0139dd52b 797 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 275 397 2.2E-8 T 29-03-2018 IPR000014 PAS domain CDC59_RS23960 67237a43dd381f436a394da0139dd52b 797 SMART SM00387 531 644 6.2E-40 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS23960 67237a43dd381f436a394da0139dd52b 797 SMART SM00388 418 485 2.8E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS23960 67237a43dd381f436a394da0139dd52b 797 SUPERFAMILY SSF55785 258 389 2.79E-17 T 29-03-2018 IPR000014 PAS domain CDC59_RS23960 67237a43dd381f436a394da0139dd52b 797 Pfam PF08447 PAS fold 42 128 1.0E-11 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 CDC59_RS23960 67237a43dd381f436a394da0139dd52b 797 Gene3D G3DSA:3.40.50.2300 658 797 4.7E-32 T 29-03-2018 CDC59_RS23960 67237a43dd381f436a394da0139dd52b 797 SMART SM00086 92 134 1.9 T 29-03-2018 IPR001610 PAC motif CDC59_RS23960 67237a43dd381f436a394da0139dd52b 797 SMART SM00086 219 261 0.02 T 29-03-2018 IPR001610 PAC motif CDC59_RS23960 67237a43dd381f436a394da0139dd52b 797 PRINTS PR00344 Bacterial sensor protein C-terminal signature 586 596 5.4E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS23960 67237a43dd381f436a394da0139dd52b 797 PRINTS PR00344 Bacterial sensor protein C-terminal signature 628 641 5.4E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS23960 67237a43dd381f436a394da0139dd52b 797 PRINTS PR00344 Bacterial sensor protein C-terminal signature 568 582 5.4E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS23960 67237a43dd381f436a394da0139dd52b 797 PRINTS PR00344 Bacterial sensor protein C-terminal signature 603 621 5.4E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS23960 67237a43dd381f436a394da0139dd52b 797 SUPERFAMILY SSF55785 29 134 1.1E-12 T 29-03-2018 IPR000014 PAS domain CDC59_RS23960 67237a43dd381f436a394da0139dd52b 797 SMART SM00091 19 87 5.0 T 29-03-2018 IPR000014 PAS domain CDC59_RS23960 67237a43dd381f436a394da0139dd52b 797 SMART SM00091 145 212 7.5E-5 T 29-03-2018 IPR000014 PAS domain CDC59_RS23960 67237a43dd381f436a394da0139dd52b 797 SMART SM00091 273 340 1.5E-6 T 29-03-2018 IPR000014 PAS domain CDC59_RS23960 67237a43dd381f436a394da0139dd52b 797 Gene3D G3DSA:3.30.450.20 29 141 6.4E-17 T 29-03-2018 CDC59_RS23960 67237a43dd381f436a394da0139dd52b 797 Gene3D G3DSA:3.30.450.20 142 270 7.0E-30 T 29-03-2018 CDC59_RS23960 67237a43dd381f436a394da0139dd52b 797 Pfam PF00512 His Kinase A (phospho-acceptor) domain 419 482 4.6E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS23960 67237a43dd381f436a394da0139dd52b 797 Pfam PF00072 Response regulator receiver domain 670 791 2.6E-18 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS23960 67237a43dd381f436a394da0139dd52b 797 SUPERFAMILY SSF47384 406 486 3.34E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS23960 67237a43dd381f436a394da0139dd52b 797 Pfam PF08448 PAS fold 280 392 2.6E-18 T 29-03-2018 IPR013656 PAS fold-4 CDC59_RS23960 67237a43dd381f436a394da0139dd52b 797 Pfam PF08448 PAS fold 153 263 1.3E-15 T 29-03-2018 IPR013656 PAS fold-4 CDC59_RS23960 67237a43dd381f436a394da0139dd52b 797 SUPERFAMILY SSF55785 132 259 8.24E-23 T 29-03-2018 IPR000014 PAS domain CDC59_RS23960 67237a43dd381f436a394da0139dd52b 797 Gene3D G3DSA:1.10.287.130 408 479 7.8E-14 T 29-03-2018 CDC59_RS23960 67237a43dd381f436a394da0139dd52b 797 SUPERFAMILY SSF52172 666 796 3.84E-28 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS11445 b79f8bab4980018466d36a8bf5fda91a 216 Pfam PF00694 Aconitase C-terminal domain 1 131 1.2E-38 T 29-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS11445 b79f8bab4980018466d36a8bf5fda91a 216 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 196 1.4E-82 T 29-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 CDC59_RS11445 b79f8bab4980018466d36a8bf5fda91a 216 Gene3D G3DSA:3.20.19.10 1 184 2.9E-49 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CDC59_RS11445 b79f8bab4980018466d36a8bf5fda91a 216 SUPERFAMILY SSF52016 1 202 3.14E-64 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CDC59_RS11445 b79f8bab4980018466d36a8bf5fda91a 216 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 210 44.121 T 29-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 CDC59_RS07680 7361e831112ef393df4b2dedc769d3bc 284 TIGRFAM TIGR01362 KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase 13 274 3.2E-120 T 29-03-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008152|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 CDC59_RS07680 7361e831112ef393df4b2dedc769d3bc 284 SUPERFAMILY SSF51569 2 275 1.74E-99 T 29-03-2018 CDC59_RS07680 7361e831112ef393df4b2dedc769d3bc 284 Gene3D G3DSA:3.20.20.70 11 277 1.4E-70 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS07680 7361e831112ef393df4b2dedc769d3bc 284 Hamap MF_00056 2-dehydro-3-deoxyphosphooctonate aldolase [kdsA]. 8 276 51.857 T 29-03-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008152|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 CDC59_RS07680 7361e831112ef393df4b2dedc769d3bc 284 Pfam PF00793 DAHP synthetase I family 5 273 2.8E-66 T 29-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 CDC59_RS18685 a0566347861bf24772471dbb48110d15 404 SUPERFAMILY SSF111369 102 327 2.48E-27 T 29-03-2018 CDC59_RS18685 a0566347861bf24772471dbb48110d15 404 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 84 382 6.9E-49 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 CDC59_RS18685 a0566347861bf24772471dbb48110d15 404 Gene3D G3DSA:2.40.50.100 206 302 5.4E-8 T 29-03-2018 CDC59_RS18685 a0566347861bf24772471dbb48110d15 404 Gene3D G3DSA:1.10.287.470 159 202 5.1E-7 T 29-03-2018 CDC59_RS18685 a0566347861bf24772471dbb48110d15 404 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 89 320 1.0E-41 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CDC59_RS18685 a0566347861bf24772471dbb48110d15 404 Gene3D G3DSA:2.40.50.100 105 158 1.1E-9 T 29-03-2018 CDC59_RS21225 526b618949db70d306f41d2ad49db762 467 Gene3D G3DSA:3.40.640.10 130 357 3.0E-38 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDC59_RS21225 526b618949db70d306f41d2ad49db762 467 SMART SM00345 18 77 1.9E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDC59_RS21225 526b618949db70d306f41d2ad49db762 467 SUPERFAMILY SSF46785 9 81 2.93E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS21225 526b618949db70d306f41d2ad49db762 467 Gene3D G3DSA:1.10.10.10 6 79 1.0E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS21225 526b618949db70d306f41d2ad49db762 467 Pfam PF00155 Aminotransferase class I and II 143 457 1.4E-30 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CDC59_RS21225 526b618949db70d306f41d2ad49db762 467 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 77 4.3E-13 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDC59_RS21225 526b618949db70d306f41d2ad49db762 467 Gene3D G3DSA:3.90.1150.10 358 466 3.5E-18 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS21225 526b618949db70d306f41d2ad49db762 467 SUPERFAMILY SSF53383 71 464 1.65E-75 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS23790 20dab46a35f5340045f8b35f62c0b958 511 Gene3D G3DSA:2.40.50.100 131 242 9.4E-12 T 29-03-2018 CDC59_RS23790 20dab46a35f5340045f8b35f62c0b958 511 Pfam PF11604 Copper binding periplasmic protein CusF 437 502 5.7E-21 T 29-03-2018 IPR021647 Copper binding periplasmic protein CusF CDC59_RS23790 20dab46a35f5340045f8b35f62c0b958 511 Gene3D G3DSA:2.40.50.100 243 425 7.5E-6 T 29-03-2018 CDC59_RS23790 20dab46a35f5340045f8b35f62c0b958 511 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 122 331 2.4E-71 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CDC59_RS23790 20dab46a35f5340045f8b35f62c0b958 511 SUPERFAMILY SSF111369 144 337 2.22E-14 T 29-03-2018 CDC59_RS23790 20dab46a35f5340045f8b35f62c0b958 511 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 218 405 1.3E-37 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 CDC59_RS16570 6bd8cd70fa9ed481ca7f9f1bdfce4c54 500 Pfam PF10142 PhoPQ-activated pathogenicity-related protein 47 420 1.4E-124 T 29-03-2018 IPR009199 PhoPQ-activated pathogenicity-related protein, PqaA type CDC59_RS16570 6bd8cd70fa9ed481ca7f9f1bdfce4c54 500 PIRSF PIRSF014728 3 497 2.7E-192 T 29-03-2018 IPR009199 PhoPQ-activated pathogenicity-related protein, PqaA type CDC59_RS16570 6bd8cd70fa9ed481ca7f9f1bdfce4c54 500 SUPERFAMILY SSF53474 194 256 4.2E-11 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS16570 6bd8cd70fa9ed481ca7f9f1bdfce4c54 500 SUPERFAMILY SSF53474 309 372 4.2E-11 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS16570 6bd8cd70fa9ed481ca7f9f1bdfce4c54 500 Gene3D G3DSA:3.40.50.1820 89 373 4.6E-9 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS09360 333291e079827227f153f1ed54526528 242 Pfam PF01323 DSBA-like thioredoxin domain 7 190 5.5E-9 T 29-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 CDC59_RS09360 333291e079827227f153f1ed54526528 242 SUPERFAMILY SSF52833 3 213 3.73E-35 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS09360 333291e079827227f153f1ed54526528 242 Gene3D G3DSA:3.40.30.10 1 217 4.1E-30 T 29-03-2018 CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 3381 3398 0.0015 T 29-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 3418 3434 0.0033 T 29-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 3435 3452 0.2 T 29-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 3399 3416 0.04 T 29-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 TIGRFAM TIGR03661 T1SS_VCA0849: type I secretion C-terminal target domain (VC_A0849 subclass) 3468 3570 1.1E-10 T 29-03-2018 IPR019960 Type I secretion C-terminal target domain, VC_A0849 subclass CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 SUPERFAMILY SSF51120 3294 3339 1.55E-26 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 SUPERFAMILY SSF51120 3380 3527 1.55E-26 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 3405 3423 - T 29-03-2018 IPR018511 Hemolysin-type calcium-binding conserved site CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 3414 3432 - T 29-03-2018 IPR018511 Hemolysin-type calcium-binding conserved site CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 PRINTS PR00313 NodO calcium binding signature 3406 3417 1.0E-7 T 29-03-2018 CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 PRINTS PR00313 NodO calcium binding signature 3436 3444 1.0E-7 T 29-03-2018 CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 PRINTS PR00313 NodO calcium binding signature 3445 3454 1.0E-7 T 29-03-2018 CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 PRINTS PR00313 NodO calcium binding signature 3418 3426 1.0E-7 T 29-03-2018 CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 Gene3D G3DSA:2.60.40.1310 1126 1229 8.5E-29 T 29-03-2018 CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 Gene3D G3DSA:2.60.40.1310 918 1020 2.0E-24 T 29-03-2018 CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 Gene3D G3DSA:2.60.40.1310 1847 1964 1.3E-25 T 29-03-2018 CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 Gene3D G3DSA:2.60.40.1310 1541 1643 1.4E-20 T 29-03-2018 CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 Gene3D G3DSA:2.60.40.1310 3081 3223 1.5E-17 T 29-03-2018 CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 Gene3D G3DSA:2.60.40.1310 2165 2250 8.4E-17 T 29-03-2018 CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 Gene3D G3DSA:2.60.40.1310 2458 2590 4.2E-26 T 29-03-2018 CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 Gene3D G3DSA:2.60.40.1310 1644 1772 2.5E-22 T 29-03-2018 CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 Gene3D G3DSA:2.60.40.1310 2660 2769 7.3E-24 T 29-03-2018 CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 Gene3D G3DSA:2.60.40.1310 2976 3080 1.8E-24 T 29-03-2018 CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 Gene3D G3DSA:2.60.40.1310 620 707 1.5E-14 T 29-03-2018 CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 Gene3D G3DSA:2.60.40.1310 1965 2060 1.0E-18 T 29-03-2018 CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 Gene3D G3DSA:2.60.40.1310 2355 2457 4.7E-24 T 29-03-2018 CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 Gene3D G3DSA:2.60.40.1310 1334 1436 5.3E-23 T 29-03-2018 CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 Gene3D G3DSA:2.60.40.1310 708 810 3.2E-22 T 29-03-2018 CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 Gene3D G3DSA:2.60.40.1310 2873 2975 5.9E-23 T 29-03-2018 CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 Gene3D G3DSA:2.60.40.1310 1021 1125 3.5E-24 T 29-03-2018 CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 Gene3D G3DSA:2.60.40.1310 2251 2354 1.6E-24 T 29-03-2018 CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 Gene3D G3DSA:2.60.40.1310 811 917 7.6E-21 T 29-03-2018 CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 Gene3D G3DSA:2.60.40.1310 1437 1540 8.1E-25 T 29-03-2018 CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 Gene3D G3DSA:2.60.40.1310 2770 2872 1.7E-23 T 29-03-2018 CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 Gene3D G3DSA:2.60.40.1310 238 329 1.7E-24 T 29-03-2018 CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 Gene3D G3DSA:2.60.40.1310 1230 1333 5.8E-25 T 29-03-2018 CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 Gene3D G3DSA:2.60.40.1310 2061 2164 2.1E-24 T 29-03-2018 CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 Gene3D G3DSA:2.60.40.1310 330 445 2.2E-26 T 29-03-2018 CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 PRINTS PR01488 Gram-negative bacterial RTX toxin determinant A family signature 2783 2804 2.5E-5 T 29-03-2018 IPR003995 RTX toxin determinant A GO:0005509|GO:0005576|GO:0009405 CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 PRINTS PR01488 Gram-negative bacterial RTX toxin determinant A family signature 3409 3430 2.5E-5 T 29-03-2018 IPR003995 RTX toxin determinant A GO:0005509|GO:0005576|GO:0009405 CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 Gene3D G3DSA:2.60.40.10 159 237 2.7E-14 T 29-03-2018 IPR013783 Immunoglobulin-like fold CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 3423 3441 - T 29-03-2018 IPR018511 Hemolysin-type calcium-binding conserved site CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 Gene3D G3DSA:2.60.40.10 446 544 1.3E-17 T 29-03-2018 IPR013783 Immunoglobulin-like fold CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 Gene3D G3DSA:2.60.40.10 545 619 2.0E-12 T 29-03-2018 IPR013783 Immunoglobulin-like fold CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 3396 3414 - T 29-03-2018 IPR018511 Hemolysin-type calcium-binding conserved site CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 Pfam PF12245 Bacterial Ig-like domain (group 3) 2974 3001 0.17 T 29-03-2018 IPR022038 Bacterial Ig-like domain CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 Pfam PF12245 Bacterial Ig-like domain (group 3) 2450 2481 1.2 T 29-03-2018 IPR022038 Bacterial Ig-like domain CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 Pfam PF12245 Bacterial Ig-like domain (group 3) 3186 3209 9.2E-4 T 29-03-2018 IPR022038 Bacterial Ig-like domain CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 Pfam PF12245 Bacterial Ig-like domain (group 3) 1117 1148 1.9 T 29-03-2018 IPR022038 Bacterial Ig-like domain CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 Pfam PF12245 Bacterial Ig-like domain (group 3) 1437 1460 4.6 T 29-03-2018 IPR022038 Bacterial Ig-like domain CDC59_RS21800 fd74b98a8a2e6b764531d7bee0ec033f 3572 Pfam PF12245 Bacterial Ig-like domain (group 3) 1221 1252 1.6 T 29-03-2018 IPR022038 Bacterial Ig-like domain CDC59_RS11505 a28ab041b4b12e51859c2f4b37979564 385 SUPERFAMILY SSF48256 17 384 1.44E-117 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CDC59_RS11505 a28ab041b4b12e51859c2f4b37979564 385 PRINTS PR00143 Citrate synthase signature 185 200 2.1E-32 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CDC59_RS11505 a28ab041b4b12e51859c2f4b37979564 385 PRINTS PR00143 Citrate synthase signature 207 235 2.1E-32 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CDC59_RS11505 a28ab041b4b12e51859c2f4b37979564 385 PRINTS PR00143 Citrate synthase signature 337 351 2.1E-32 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CDC59_RS11505 a28ab041b4b12e51859c2f4b37979564 385 PRINTS PR00143 Citrate synthase signature 260 280 2.1E-32 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CDC59_RS11505 a28ab041b4b12e51859c2f4b37979564 385 PRINTS PR00143 Citrate synthase signature 317 333 2.1E-32 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CDC59_RS11505 a28ab041b4b12e51859c2f4b37979564 385 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 17 384 1.1E-146 T 29-03-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 CDC59_RS11505 a28ab041b4b12e51859c2f4b37979564 385 ProSitePatterns PS00480 Citrate synthase signature. 267 279 - T 29-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CDC59_RS11505 a28ab041b4b12e51859c2f4b37979564 385 PIRSF PIRSF001369 11 385 2.9E-102 T 29-03-2018 IPR024176 Citrate synthase, bacterial-type CDC59_RS11505 a28ab041b4b12e51859c2f4b37979564 385 Gene3D G3DSA:1.10.580.10 24 364 8.0E-74 T 29-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain CDC59_RS11505 a28ab041b4b12e51859c2f4b37979564 385 Pfam PF00285 Citrate synthase, C-terminal domain 18 366 1.4E-103 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CDC59_RS18715 8e50e36c2625d93034645e1bad95af12 606 Gene3D G3DSA:1.10.287.950 318 516 1.7E-46 T 29-03-2018 CDC59_RS18715 8e50e36c2625d93034645e1bad95af12 606 SMART SM00304 212 264 2.9E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CDC59_RS18715 8e50e36c2625d93034645e1bad95af12 606 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 325 480 1.4E-50 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CDC59_RS18715 8e50e36c2625d93034645e1bad95af12 606 SUPERFAMILY SSF47170 52 147 7.59E-7 T 29-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 CDC59_RS18715 8e50e36c2625d93034645e1bad95af12 606 Gene3D G3DSA:1.20.120.30 24 184 1.4E-34 T 29-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain CDC59_RS18715 8e50e36c2625d93034645e1bad95af12 606 SMART SM00283 265 512 6.6E-83 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CDC59_RS18715 8e50e36c2625d93034645e1bad95af12 606 Pfam PF02203 Tar ligand binding domain homologue 1 174 1.3E-52 T 29-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 CDC59_RS18715 8e50e36c2625d93034645e1bad95af12 606 Pfam PF00672 HAMP domain 212 260 1.5E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CDC59_RS18715 8e50e36c2625d93034645e1bad95af12 606 SUPERFAMILY SSF58104 232 513 7.19E-71 T 29-03-2018 CDC59_RS18715 8e50e36c2625d93034645e1bad95af12 606 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 392 421 2.3E-55 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS18715 8e50e36c2625d93034645e1bad95af12 606 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 440 469 2.3E-55 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS18715 8e50e36c2625d93034645e1bad95af12 606 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 363 390 2.3E-55 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS18715 8e50e36c2625d93034645e1bad95af12 606 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 286 315 2.3E-55 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS18715 8e50e36c2625d93034645e1bad95af12 606 Gene3D G3DSA:1.10.287.950 232 316 3.4E-11 T 29-03-2018 CDC59_RS12905 25be605fce064d0af6e0da9cd0dce449 250 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 187 6.3E-6 T 29-03-2018 CDC59_RS12905 25be605fce064d0af6e0da9cd0dce449 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 248 1.4E-59 T 29-03-2018 CDC59_RS12905 25be605fce064d0af6e0da9cd0dce449 250 SUPERFAMILY SSF51735 7 249 1.92E-76 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS12905 25be605fce064d0af6e0da9cd0dce449 250 Gene3D G3DSA:3.40.50.720 3 50 4.9E-7 T 29-03-2018 CDC59_RS12905 25be605fce064d0af6e0da9cd0dce449 250 Gene3D G3DSA:3.40.50.720 51 250 2.4E-62 T 29-03-2018 CDC59_RS12905 25be605fce064d0af6e0da9cd0dce449 250 TIGRFAM TIGR01829 AcAcCoA_reduct: acetoacetyl-CoA reductase 7 249 4.0E-103 T 29-03-2018 IPR011283 Acetoacetyl-CoA reductase GO:0005737|GO:0018454|GO:0042619|GO:0055114 KEGG: 00630+1.1.1.36|KEGG: 00650+1.1.1.36|MetaCyc: PWY-5676|MetaCyc: PWY-5741|MetaCyc: PWY-7216 CDC59_RS12905 25be605fce064d0af6e0da9cd0dce449 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CDC59_RS12905 25be605fce064d0af6e0da9cd0dce449 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 2.6E-48 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS12905 25be605fce064d0af6e0da9cd0dce449 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.6E-48 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS12905 25be605fce064d0af6e0da9cd0dce449 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 2.6E-48 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS12905 25be605fce064d0af6e0da9cd0dce449 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 2.6E-48 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS12905 25be605fce064d0af6e0da9cd0dce449 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 2.6E-48 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS12905 25be605fce064d0af6e0da9cd0dce449 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 2.6E-48 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS12905 25be605fce064d0af6e0da9cd0dce449 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 6.6E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS12905 25be605fce064d0af6e0da9cd0dce449 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 6.6E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS12905 25be605fce064d0af6e0da9cd0dce449 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 6.6E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS20930 0b4466d14122cca927b224cbfc47dda1 414 Gene3D G3DSA:1.20.1250.20 1 189 1.3E-9 T 29-03-2018 CDC59_RS20930 0b4466d14122cca927b224cbfc47dda1 414 Gene3D G3DSA:1.20.1250.20 197 388 1.4E-7 T 29-03-2018 CDC59_RS20930 0b4466d14122cca927b224cbfc47dda1 414 SUPERFAMILY SSF103473 15 390 4.45E-18 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS02065 69f39c3ba09e9c8deadbab0cd1031eb5 254 SUPERFAMILY SSF100950 71 230 1.97E-28 T 29-03-2018 CDC59_RS02065 69f39c3ba09e9c8deadbab0cd1031eb5 254 SMART SM00420 4 56 6.6E-16 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CDC59_RS02065 69f39c3ba09e9c8deadbab0cd1031eb5 254 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 22 36 5.8E-8 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CDC59_RS02065 69f39c3ba09e9c8deadbab0cd1031eb5 254 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 36 54 5.8E-8 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CDC59_RS02065 69f39c3ba09e9c8deadbab0cd1031eb5 254 Gene3D G3DSA:1.10.10.10 1 58 1.8E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS02065 69f39c3ba09e9c8deadbab0cd1031eb5 254 SMART SM01134 70 231 4.6E-71 T 29-03-2018 CDC59_RS02065 69f39c3ba09e9c8deadbab0cd1031eb5 254 SUPERFAMILY SSF46785 3 71 2.33E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS02065 69f39c3ba09e9c8deadbab0cd1031eb5 254 Pfam PF00455 DeoR C terminal sensor domain 72 229 1.4E-51 T 29-03-2018 IPR014036 DeoR C-terminal sensor domain CDC59_RS02065 69f39c3ba09e9c8deadbab0cd1031eb5 254 Pfam PF08220 DeoR-like helix-turn-helix domain 4 59 5.8E-18 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CDC59_RS02065 69f39c3ba09e9c8deadbab0cd1031eb5 254 ProSitePatterns PS00894 DeoR-type HTH domain signature. 4 38 - T 29-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CDC59_RS02065 69f39c3ba09e9c8deadbab0cd1031eb5 254 Gene3D G3DSA:3.40.50.1360 62 249 9.4E-40 T 29-03-2018 CDC59_RS19770 e31c41cec2cfdfee14f8a2371efbf710 793 SUPERFAMILY SSF56024 470 533 1.24E-16 T 29-03-2018 CDC59_RS19770 e31c41cec2cfdfee14f8a2371efbf710 793 SUPERFAMILY SSF56024 588 667 1.24E-16 T 29-03-2018 CDC59_RS19770 e31c41cec2cfdfee14f8a2371efbf710 793 SUPERFAMILY SSF56024 376 409 1.24E-16 T 29-03-2018 CDC59_RS19770 e31c41cec2cfdfee14f8a2371efbf710 793 SMART SM00155 594 621 3.3E-4 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CDC59_RS19770 e31c41cec2cfdfee14f8a2371efbf710 793 SMART SM00155 156 183 2.8E-5 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CDC59_RS19770 e31c41cec2cfdfee14f8a2371efbf710 793 Gene3D G3DSA:3.30.870.10 12 328 2.0E-34 T 29-03-2018 CDC59_RS19770 e31c41cec2cfdfee14f8a2371efbf710 793 Pfam PF00614 Phospholipase D Active site motif 158 183 6.1E-9 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CDC59_RS19770 e31c41cec2cfdfee14f8a2371efbf710 793 Pfam PF00614 Phospholipase D Active site motif 598 621 6.0E-5 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CDC59_RS19770 e31c41cec2cfdfee14f8a2371efbf710 793 Gene3D G3DSA:3.30.870.10 334 678 6.8E-34 T 29-03-2018 CDC59_RS19770 e31c41cec2cfdfee14f8a2371efbf710 793 SUPERFAMILY SSF56024 297 355 3.93E-35 T 29-03-2018 CDC59_RS19770 e31c41cec2cfdfee14f8a2371efbf710 793 SUPERFAMILY SSF56024 31 187 3.93E-35 T 29-03-2018 CDC59_RS18785 ca1da6b981b209187421838c5f8a5675 347 Gene3D G3DSA:3.30.70.270 163 330 1.9E-48 T 29-03-2018 CDC59_RS18785 ca1da6b981b209187421838c5f8a5675 347 SUPERFAMILY SSF55073 178 329 1.33E-40 T 29-03-2018 IPR029787 Nucleotide cyclase CDC59_RS18785 ca1da6b981b209187421838c5f8a5675 347 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 170 329 1.1E-40 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS18785 ca1da6b981b209187421838c5f8a5675 347 SMART SM00267 162 329 5.8E-53 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS18785 ca1da6b981b209187421838c5f8a5675 347 Pfam PF00990 Diguanylate cyclase, GGDEF domain 173 325 1.5E-35 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS02465 5ac4a743d305b3aa7717d82e3e13898f 219 Gene3D G3DSA:3.30.70.60 104 210 6.8E-24 T 29-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 CDC59_RS02465 5ac4a743d305b3aa7717d82e3e13898f 219 PIRSF PIRSF016482 10 215 5.4E-46 T 29-03-2018 IPR007445 Pilus assembly protein, PilO CDC59_RS02465 5ac4a743d305b3aa7717d82e3e13898f 219 Gene3D G3DSA:1.10.287.540 68 103 3.5E-8 T 29-03-2018 CDC59_RS02465 5ac4a743d305b3aa7717d82e3e13898f 219 Pfam PF04350 Pilus assembly protein, PilO 62 199 8.6E-43 T 29-03-2018 IPR007445 Pilus assembly protein, PilO CDC59_RS04730 a78aa4abf8ba66997c7433733552d3c2 230 TIGRFAM TIGR02796 tolQ: protein TolQ 11 227 1.1E-88 T 29-03-2018 IPR014163 Tol-Pal system, TolQ GO:0015031|GO:0016021 CDC59_RS04730 a78aa4abf8ba66997c7433733552d3c2 230 Pfam PF01618 MotA/TolQ/ExbB proton channel family 84 215 1.6E-42 T 29-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 CDC59_RS04730 a78aa4abf8ba66997c7433733552d3c2 230 Gene3D G3DSA:1.10.3720.10 9 226 5.3E-4 T 29-03-2018 CDC59_RS17700 f0247c54d84d7ede976d4234ba0cd2f6 154 SUPERFAMILY SSF46785 18 149 1.04E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS17700 f0247c54d84d7ede976d4234ba0cd2f6 154 SMART SM00347 35 135 1.0E-22 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS17700 f0247c54d84d7ede976d4234ba0cd2f6 154 Gene3D G3DSA:1.10.10.10 1 153 4.2E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS17700 f0247c54d84d7ede976d4234ba0cd2f6 154 Pfam PF01047 MarR family 42 99 1.3E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS18580 d3961eb51f5fc051260f5c45a2df88b6 227 SMART SM00342 100 183 2.3E-19 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CDC59_RS18580 d3961eb51f5fc051260f5c45a2df88b6 227 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 152 167 3.3E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CDC59_RS18580 d3961eb51f5fc051260f5c45a2df88b6 227 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 167 183 3.3E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CDC59_RS18580 d3961eb51f5fc051260f5c45a2df88b6 227 Gene3D G3DSA:1.10.10.60 135 188 1.3E-11 T 29-03-2018 CDC59_RS18580 d3961eb51f5fc051260f5c45a2df88b6 227 Pfam PF12833 Helix-turn-helix domain 106 184 4.5E-17 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CDC59_RS18580 d3961eb51f5fc051260f5c45a2df88b6 227 Gene3D G3DSA:1.10.10.60 81 134 8.1E-7 T 29-03-2018 CDC59_RS18580 d3961eb51f5fc051260f5c45a2df88b6 227 SUPERFAMILY SSF46689 133 184 1.5E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS23655 f1c11ae8118c80d2a1297dfa406dce2f 389 Gene3D G3DSA:3.40.640.10 19 258 9.1E-56 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDC59_RS23655 f1c11ae8118c80d2a1297dfa406dce2f 389 Gene3D G3DSA:3.90.1150.10 259 371 5.0E-23 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS23655 f1c11ae8118c80d2a1297dfa406dce2f 389 PIRSF PIRSF005572 8 387 2.6E-101 T 29-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CDC59_RS23655 f1c11ae8118c80d2a1297dfa406dce2f 389 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 200 219 - T 29-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CDC59_RS23655 f1c11ae8118c80d2a1297dfa406dce2f 389 SUPERFAMILY SSF53383 8 377 3.63E-89 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS23655 f1c11ae8118c80d2a1297dfa406dce2f 389 Pfam PF00266 Aminotransferase class-V 11 356 2.2E-72 T 29-03-2018 IPR000192 Aminotransferase class V domain CDC59_RS22970 89c55c1d61c15f16c6e91971257dbfdd 370 Gene3D G3DSA:3.40.1800.10 79 158 6.9E-12 T 29-03-2018 CDC59_RS22970 89c55c1d61c15f16c6e91971257dbfdd 370 Pfam PF01844 HNH endonuclease 101 146 1.1E-4 T 29-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 CDC59_RS12605 2f012c1cc8b464661c4fe0deccfacda3 447 Gene3D G3DSA:2.30.30.60 281 328 9.3E-8 T 29-03-2018 CDC59_RS12605 2f012c1cc8b464661c4fe0deccfacda3 447 Pfam PF00924 Mechanosensitive ion channel 223 420 1.5E-42 T 29-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 CDC59_RS12605 2f012c1cc8b464661c4fe0deccfacda3 447 Gene3D G3DSA:3.30.70.100 329 425 1.9E-19 T 29-03-2018 CDC59_RS12605 2f012c1cc8b464661c4fe0deccfacda3 447 SUPERFAMILY SSF82689 331 430 3.01E-26 T 29-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 CDC59_RS12605 2f012c1cc8b464661c4fe0deccfacda3 447 SUPERFAMILY SSF82861 181 263 1.23E-9 T 29-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 CDC59_RS12605 2f012c1cc8b464661c4fe0deccfacda3 447 SUPERFAMILY SSF50182 265 328 1.96E-11 T 29-03-2018 IPR010920 LSM domain CDC59_RS02655 dba6ad1c1dbbc60df780596faa53fad2 503 Gene3D G3DSA:1.10.287.130 241 311 9.6E-11 T 29-03-2018 CDC59_RS02655 dba6ad1c1dbbc60df780596faa53fad2 503 Gene3D G3DSA:3.30.565.10 321 495 5.0E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS02655 dba6ad1c1dbbc60df780596faa53fad2 503 Pfam PF08521 Two-component sensor kinase N-terminal 24 172 7.7E-40 T 29-03-2018 IPR013727 Two-component sensor kinase, N-terminal CDC59_RS02655 dba6ad1c1dbbc60df780596faa53fad2 503 Gene3D G3DSA:1.20.5.1040 152 197 0.11 T 29-03-2018 CDC59_RS02655 dba6ad1c1dbbc60df780596faa53fad2 503 Gene3D G3DSA:1.20.5.1040 10 59 0.091 T 29-03-2018 CDC59_RS02655 dba6ad1c1dbbc60df780596faa53fad2 503 SMART SM00387 363 489 2.4E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS02655 dba6ad1c1dbbc60df780596faa53fad2 503 SMART SM00388 250 315 4.7E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS02655 dba6ad1c1dbbc60df780596faa53fad2 503 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 365 487 6.4E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS02655 dba6ad1c1dbbc60df780596faa53fad2 503 Pfam PF00512 His Kinase A (phospho-acceptor) domain 251 313 4.1E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS02655 dba6ad1c1dbbc60df780596faa53fad2 503 SUPERFAMILY SSF47384 233 313 2.55E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS02655 dba6ad1c1dbbc60df780596faa53fad2 503 PRINTS PR00344 Bacterial sensor protein C-terminal signature 444 462 3.2E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS02655 dba6ad1c1dbbc60df780596faa53fad2 503 PRINTS PR00344 Bacterial sensor protein C-terminal signature 400 414 3.2E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS02655 dba6ad1c1dbbc60df780596faa53fad2 503 SUPERFAMILY SSF55874 305 487 1.7E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS10800 1bf8463df1f0ef3cddee647303b6a951 430 Pfam PF03631 Virulence factor BrkB 29 275 2.5E-55 T 29-03-2018 IPR017039 Virulence factor BrkB CDC59_RS10800 1bf8463df1f0ef3cddee647303b6a951 430 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 24 275 1.7E-70 T 29-03-2018 IPR017039 Virulence factor BrkB CDC59_RS10800 1bf8463df1f0ef3cddee647303b6a951 430 Hamap MF_00672 UPF0761 membrane protein YihY [yihY]. 8 306 23.218 T 29-03-2018 IPR023679 Uncharacterised protein family UPF0761, bacterial CDC59_RS11695 9cdaf9e065b1e6820b3036607c31564c 406 Gene3D G3DSA:1.10.3470.10 53 372 9.6E-30 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CDC59_RS11695 9cdaf9e065b1e6820b3036607c31564c 406 TIGRFAM TIGR03408 urea_trans_UrtC: urea ABC transporter, permease protein UrtC 52 365 4.3E-132 T 29-03-2018 IPR017778 ABC transporter, urea, permease protein, UrtC CDC59_RS11695 9cdaf9e065b1e6820b3036607c31564c 406 Pfam PF02653 Branched-chain amino acid transport system / permease component 60 354 1.1E-39 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CDC59_RS17365 a5840359aeb03799a5d63fa4a1664b6f 413 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 71 376 1.5E-16 T 29-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 CDC59_RS17365 a5840359aeb03799a5d63fa4a1664b6f 413 SUPERFAMILY SSF51419 23 281 4.94E-63 T 29-03-2018 IPR029066 PLP-binding barrel CDC59_RS17365 a5840359aeb03799a5d63fa4a1664b6f 413 PRINTS PR01182 Ornithine decarboxylase signature 44 71 1.1E-7 T 29-03-2018 IPR002433 Ornithine decarboxylase GO:0006596 CDC59_RS17365 a5840359aeb03799a5d63fa4a1664b6f 413 PRINTS PR01182 Ornithine decarboxylase signature 87 111 1.1E-7 T 29-03-2018 IPR002433 Ornithine decarboxylase GO:0006596 CDC59_RS17365 a5840359aeb03799a5d63fa4a1664b6f 413 PRINTS PR01182 Ornithine decarboxylase signature 363 376 1.1E-7 T 29-03-2018 IPR002433 Ornithine decarboxylase GO:0006596 CDC59_RS17365 a5840359aeb03799a5d63fa4a1664b6f 413 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 46 64 6.0E-9 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CDC59_RS17365 a5840359aeb03799a5d63fa4a1664b6f 413 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 66 78 6.0E-9 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CDC59_RS17365 a5840359aeb03799a5d63fa4a1664b6f 413 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 268 287 6.0E-9 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CDC59_RS17365 a5840359aeb03799a5d63fa4a1664b6f 413 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 184 197 6.0E-9 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CDC59_RS17365 a5840359aeb03799a5d63fa4a1664b6f 413 Gene3D G3DSA:3.20.20.10 24 268 3.7E-59 T 29-03-2018 IPR029066 PLP-binding barrel CDC59_RS17365 a5840359aeb03799a5d63fa4a1664b6f 413 SUPERFAMILY SSF50621 249 394 1.97E-35 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CDC59_RS17365 a5840359aeb03799a5d63fa4a1664b6f 413 Gene3D G3DSA:2.40.37.10 269 406 3.8E-33 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CDC59_RS17365 a5840359aeb03799a5d63fa4a1664b6f 413 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 25 278 4.7E-33 T 29-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 CDC59_RS07330 bcbd30b666bdb8e4e3945b041d3e4623 199 SUPERFAMILY SSF88659 125 187 2.24E-18 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS07330 bcbd30b666bdb8e4e3945b041d3e4623 199 Pfam PF04542 Sigma-70 region 2 25 92 1.6E-18 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS07330 bcbd30b666bdb8e4e3945b041d3e4623 199 Pfam PF08281 Sigma-70, region 4 133 182 2.3E-18 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS07330 bcbd30b666bdb8e4e3945b041d3e4623 199 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 47 78 - T 29-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS07330 bcbd30b666bdb8e4e3945b041d3e4623 199 Gene3D G3DSA:1.10.1740.10 1 115 8.6E-32 T 29-03-2018 CDC59_RS07330 bcbd30b666bdb8e4e3945b041d3e4623 199 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 187 4.3E-33 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS07330 bcbd30b666bdb8e4e3945b041d3e4623 199 Gene3D G3DSA:1.10.10.10 116 190 1.6E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS07330 bcbd30b666bdb8e4e3945b041d3e4623 199 TIGRFAM TIGR02939 RpoE_Sigma70: RNA polymerase sigma factor RpoE 2 191 2.6E-97 T 29-03-2018 IPR014286 RNA polymerase sigma-70 RpoE type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS07330 bcbd30b666bdb8e4e3945b041d3e4623 199 SUPERFAMILY SSF88946 3 110 4.55E-33 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS00630 e3514293f9e959c9a5f49c7d2993649e 179 SMART SM00317 29 147 4.1E-27 T 29-03-2018 IPR001214 SET domain GO:0005515 CDC59_RS00630 e3514293f9e959c9a5f49c7d2993649e 179 SUPERFAMILY SSF82199 27 167 3.27E-42 T 29-03-2018 CDC59_RS00630 e3514293f9e959c9a5f49c7d2993649e 179 SMART SM00508 154 170 0.0055 T 29-03-2018 IPR003616 Post-SET domain KEGG: 00310+2.1.1.43|Reactome: R-HSA-3214841 CDC59_RS00630 e3514293f9e959c9a5f49c7d2993649e 179 Gene3D G3DSA:2.170.270.10 12 170 2.3E-43 T 29-03-2018 CDC59_RS00630 e3514293f9e959c9a5f49c7d2993649e 179 Pfam PF00856 SET domain 40 141 2.7E-17 T 29-03-2018 IPR001214 SET domain GO:0005515 CDC59_RS00975 ddc9ba07c738e82d43c26c49cac42449 458 TIGRFAM TIGR00720 sda_mono: L-serine ammonia-lyase 3 455 1.8E-215 T 29-03-2018 IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CDC59_RS00975 ddc9ba07c738e82d43c26c49cac42449 458 Pfam PF03315 Serine dehydratase beta chain 4 156 2.9E-58 T 29-03-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CDC59_RS00975 ddc9ba07c738e82d43c26c49cac42449 458 Pfam PF03313 Serine dehydratase alpha chain 188 452 2.8E-102 T 29-03-2018 IPR005130 Serine dehydratase-like, alpha subunit CDC59_RS00975 ddc9ba07c738e82d43c26c49cac42449 458 Gene3D G3DSA:1.10.4100.10 234 444 6.8E-34 T 29-03-2018 CDC59_RS00975 ddc9ba07c738e82d43c26c49cac42449 458 Gene3D G3DSA:3.30.1330.90 11 160 1.0E-56 T 29-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CDC59_RS00975 ddc9ba07c738e82d43c26c49cac42449 458 SUPERFAMILY SSF143548 17 157 3.66E-46 T 29-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CDC59_RS14145 97898d1dd6c38a9cac957babe3fc7c1e 359 Gene3D G3DSA:3.40.640.10 25 259 5.6E-29 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDC59_RS14145 97898d1dd6c38a9cac957babe3fc7c1e 359 PIRSF PIRSF038940 13 357 7.0E-157 T 29-03-2018 IPR026273 Low specificity L-threonine aldolase GO:0004793|GO:0006567 KEGG: 00260+4.1.2.48 CDC59_RS14145 97898d1dd6c38a9cac957babe3fc7c1e 359 Gene3D G3DSA:3.90.1150.10 260 359 2.9E-29 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS14145 97898d1dd6c38a9cac957babe3fc7c1e 359 SUPERFAMILY SSF53383 15 354 3.48E-97 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS14145 97898d1dd6c38a9cac957babe3fc7c1e 359 Pfam PF01212 Beta-eliminating lyase 16 301 7.2E-60 T 29-03-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 CDC59_RS11990 395e51616b02dd703c43671842819667 138 Pfam PF05713 Bacterial mobilisation protein (MobC) 89 126 3.1E-8 T 29-03-2018 IPR008687 Bacterial mobilisation CDC59_RS13260 23cbb9bb0d5050dc41aa010ef3940ed5 903 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 28 148 1.2E-12 T 29-03-2018 IPR000014 PAS domain CDC59_RS13260 23cbb9bb0d5050dc41aa010ef3940ed5 903 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 336 469 4.0E-6 T 29-03-2018 IPR000014 PAS domain CDC59_RS13260 23cbb9bb0d5050dc41aa010ef3940ed5 903 SMART SM00065 184 336 2.8E-7 T 29-03-2018 IPR003018 GAF domain GO:0005515 CDC59_RS13260 23cbb9bb0d5050dc41aa010ef3940ed5 903 Gene3D G3DSA:3.30.450.40 171 338 4.6E-21 T 29-03-2018 IPR029016 GAF domain-like CDC59_RS13260 23cbb9bb0d5050dc41aa010ef3940ed5 903 Pfam PF00989 PAS fold 29 138 2.5E-9 T 29-03-2018 IPR013767 PAS fold GO:0006355 CDC59_RS13260 23cbb9bb0d5050dc41aa010ef3940ed5 903 SUPERFAMILY SSF141868 649 896 8.76E-86 T 29-03-2018 IPR001633 EAL domain CDC59_RS13260 23cbb9bb0d5050dc41aa010ef3940ed5 903 SMART SM00052 644 889 3.0E-111 T 29-03-2018 IPR001633 EAL domain CDC59_RS13260 23cbb9bb0d5050dc41aa010ef3940ed5 903 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 469 633 3.4E-46 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS13260 23cbb9bb0d5050dc41aa010ef3940ed5 903 Pfam PF13185 GAF domain 185 327 1.9E-12 T 29-03-2018 IPR003018 GAF domain GO:0005515 CDC59_RS13260 23cbb9bb0d5050dc41aa010ef3940ed5 903 Pfam PF00563 EAL domain 650 884 2.6E-72 T 29-03-2018 IPR001633 EAL domain CDC59_RS13260 23cbb9bb0d5050dc41aa010ef3940ed5 903 Gene3D G3DSA:3.30.450.20 339 471 1.1E-19 T 29-03-2018 CDC59_RS13260 23cbb9bb0d5050dc41aa010ef3940ed5 903 SUPERFAMILY SSF55785 331 459 2.44E-15 T 29-03-2018 IPR000014 PAS domain CDC59_RS13260 23cbb9bb0d5050dc41aa010ef3940ed5 903 Gene3D G3DSA:3.30.450.20 146 170 2.2E-4 T 29-03-2018 CDC59_RS13260 23cbb9bb0d5050dc41aa010ef3940ed5 903 SMART SM00091 340 406 0.0054 T 29-03-2018 IPR000014 PAS domain CDC59_RS13260 23cbb9bb0d5050dc41aa010ef3940ed5 903 SMART SM00091 28 94 9.1E-8 T 29-03-2018 IPR000014 PAS domain CDC59_RS13260 23cbb9bb0d5050dc41aa010ef3940ed5 903 PIRSF PIRSF005925 461 901 4.1E-141 T 29-03-2018 IPR012226 Diguanylate cyclase/phosphodiesterase CDC59_RS13260 23cbb9bb0d5050dc41aa010ef3940ed5 903 PIRSF PIRSF005925 30 350 1.0E-33 T 29-03-2018 IPR012226 Diguanylate cyclase/phosphodiesterase CDC59_RS13260 23cbb9bb0d5050dc41aa010ef3940ed5 903 SUPERFAMILY SSF55785 45 150 6.43E-15 T 29-03-2018 IPR000014 PAS domain CDC59_RS13260 23cbb9bb0d5050dc41aa010ef3940ed5 903 SUPERFAMILY SSF55073 478 635 5.63E-55 T 29-03-2018 IPR029787 Nucleotide cyclase CDC59_RS13260 23cbb9bb0d5050dc41aa010ef3940ed5 903 Pfam PF13188 PAS domain 340 374 1.2E-4 T 29-03-2018 IPR000014 PAS domain CDC59_RS13260 23cbb9bb0d5050dc41aa010ef3940ed5 903 SUPERFAMILY SSF55781 186 339 3.27E-20 T 29-03-2018 IPR029016 GAF domain-like CDC59_RS13260 23cbb9bb0d5050dc41aa010ef3940ed5 903 Gene3D G3DSA:3.20.20.450 642 901 5.9E-98 T 29-03-2018 IPR001633 EAL domain CDC59_RS13260 23cbb9bb0d5050dc41aa010ef3940ed5 903 Gene3D G3DSA:3.30.70.270 472 641 1.1E-66 T 29-03-2018 CDC59_RS13260 23cbb9bb0d5050dc41aa010ef3940ed5 903 SMART SM00267 462 634 3.5E-74 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS13260 23cbb9bb0d5050dc41aa010ef3940ed5 903 Pfam PF00990 Diguanylate cyclase, GGDEF domain 473 630 1.9E-52 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS13260 23cbb9bb0d5050dc41aa010ef3940ed5 903 Gene3D G3DSA:3.30.450.20 23 145 1.8E-20 T 29-03-2018 CDC59_RS14630 2748368bb37379686838a7e04cb8217a 428 Hamap MF_01300 C4-dicarboxylate transport protein [dctA]. 2 428 38.755 T 29-03-2018 IPR023954 C4-dicarboxylate transport protein GO:0006835|GO:0015293|GO:0016021 CDC59_RS14630 2748368bb37379686838a7e04cb8217a 428 Gene3D G3DSA:1.10.3860.10 2 408 7.0E-115 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CDC59_RS14630 2748368bb37379686838a7e04cb8217a 428 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 295 318 - T 29-03-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site CDC59_RS14630 2748368bb37379686838a7e04cb8217a 428 SUPERFAMILY SSF118215 9 402 1.57E-119 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CDC59_RS14630 2748368bb37379686838a7e04cb8217a 428 PRINTS PR00173 Glutamate-aspartate symporter signature 292 318 2.2E-21 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CDC59_RS14630 2748368bb37379686838a7e04cb8217a 428 PRINTS PR00173 Glutamate-aspartate symporter signature 74 99 2.2E-21 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CDC59_RS14630 2748368bb37379686838a7e04cb8217a 428 PRINTS PR00173 Glutamate-aspartate symporter signature 145 167 2.2E-21 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CDC59_RS14630 2748368bb37379686838a7e04cb8217a 428 PRINTS PR00173 Glutamate-aspartate symporter signature 327 346 2.2E-21 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CDC59_RS14630 2748368bb37379686838a7e04cb8217a 428 PRINTS PR00173 Glutamate-aspartate symporter signature 7 27 2.2E-21 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CDC59_RS14630 2748368bb37379686838a7e04cb8217a 428 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 36 51 - T 29-03-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site CDC59_RS14630 2748368bb37379686838a7e04cb8217a 428 Pfam PF00375 Sodium:dicarboxylate symporter family 9 401 5.5E-108 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CDC59_RS13740 92bd9d16d47018ec731043ef5b048769 357 SUPERFAMILY SSF52540 34 265 1.12E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS13740 92bd9d16d47018ec731043ef5b048769 357 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 357 183.951 T 29-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 CDC59_RS13740 92bd9d16d47018ec731043ef5b048769 357 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 23 249 1.0E-117 T 29-03-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 CDC59_RS13740 92bd9d16d47018ec731043ef5b048769 357 SUPERFAMILY SSF46785 270 344 2.24E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS13740 92bd9d16d47018ec731043ef5b048769 357 SMART SM00382 65 192 1.8E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS13740 92bd9d16d47018ec731043ef5b048769 357 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 267 340 9.9E-34 T 29-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 CDC59_RS13740 92bd9d16d47018ec731043ef5b048769 357 Gene3D G3DSA:1.10.10.10 271 341 1.4E-34 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS13740 92bd9d16d47018ec731043ef5b048769 357 Gene3D G3DSA:3.40.50.300 32 195 1.5E-27 T 29-03-2018 CDC59_RS13740 92bd9d16d47018ec731043ef5b048769 357 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 38 340 1.8E-148 T 29-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 CDC59_RS13740 92bd9d16d47018ec731043ef5b048769 357 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 271 345 8.0E-38 T 29-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 CDC59_RS13740 92bd9d16d47018ec731043ef5b048769 357 Gene3D G3DSA:1.10.8.60 198 268 9.7E-32 T 29-03-2018 CDC59_RS20740 3ec1e1363de85ca707d186d02ff890a5 1945 ProSitePatterns PS00211 ABC transporters family signature. 1434 1448 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS20740 3ec1e1363de85ca707d186d02ff890a5 1945 ProSitePatterns PS00211 ABC transporters family signature. 1814 1828 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS20740 3ec1e1363de85ca707d186d02ff890a5 1945 Pfam PF00005 ABC transporter 645 874 2.2E-5 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS20740 3ec1e1363de85ca707d186d02ff890a5 1945 SUPERFAMILY SSF52540 6 197 5.34E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS20740 3ec1e1363de85ca707d186d02ff890a5 1945 SUPERFAMILY SSF52540 452 589 5.34E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS20740 3ec1e1363de85ca707d186d02ff890a5 1945 SUPERFAMILY SSF52540 1377 1516 1.24E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS20740 3ec1e1363de85ca707d186d02ff890a5 1945 SUPERFAMILY SSF52540 1020 1219 1.24E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS20740 3ec1e1363de85ca707d186d02ff890a5 1945 Gene3D G3DSA:3.40.50.300 624 986 3.2E-50 T 29-03-2018 CDC59_RS20740 3ec1e1363de85ca707d186d02ff890a5 1945 Gene3D G3DSA:3.40.50.300 1007 1052 0.22 T 29-03-2018 CDC59_RS20740 3ec1e1363de85ca707d186d02ff890a5 1945 ProSitePatterns PS00211 ABC transporters family signature. 855 869 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS20740 3ec1e1363de85ca707d186d02ff890a5 1945 Gene3D G3DSA:3.40.50.300 1053 1084 0.019 T 29-03-2018 CDC59_RS20740 3ec1e1363de85ca707d186d02ff890a5 1945 Gene3D G3DSA:1.20.1580.10 93 507 7.4E-80 T 29-03-2018 CDC59_RS20740 3ec1e1363de85ca707d186d02ff890a5 1945 Gene3D G3DSA:3.40.50.300 5 53 5.0E-5 T 29-03-2018 CDC59_RS20740 3ec1e1363de85ca707d186d02ff890a5 1945 Gene3D G3DSA:1.20.1580.10 1108 1434 1.5E-60 T 29-03-2018 CDC59_RS20740 3ec1e1363de85ca707d186d02ff890a5 1945 Gene3D G3DSA:3.40.50.300 1566 1678 2.5E-5 T 29-03-2018 CDC59_RS20740 3ec1e1363de85ca707d186d02ff890a5 1945 SUPERFAMILY SSF52540 1663 1907 1.83E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS20740 3ec1e1363de85ca707d186d02ff890a5 1945 SUPERFAMILY SSF52540 1568 1616 1.83E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS20740 3ec1e1363de85ca707d186d02ff890a5 1945 Gene3D G3DSA:1.20.1580.10 1679 1814 2.0E-43 T 29-03-2018 CDC59_RS20740 3ec1e1363de85ca707d186d02ff890a5 1945 SMART SM00382 654 948 0.32 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS20740 3ec1e1363de85ca707d186d02ff890a5 1945 SMART SM00382 1038 1511 5.9 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS20740 3ec1e1363de85ca707d186d02ff890a5 1945 SMART SM00382 1587 1899 2.2 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS20740 3ec1e1363de85ca707d186d02ff890a5 1945 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 6 966 6.8E-277 T 29-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 CDC59_RS20740 3ec1e1363de85ca707d186d02ff890a5 1945 SUPERFAMILY SSF52540 638 955 8.14E-36 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS07290 a3198419eae09065893d87cabd3538fc 59 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 55 1.4E-20 T 29-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS07290 a3198419eae09065893d87cabd3538fc 59 SUPERFAMILY SSF57829 2 55 1.71E-17 T 29-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CDC59_RS07290 a3198419eae09065893d87cabd3538fc 59 Pfam PF01783 Ribosomal L32p protein family 2 55 8.6E-19 T 29-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS07290 a3198419eae09065893d87cabd3538fc 59 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 54 16.62 T 29-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS12760 2086d43f1fdf169174119d1dd1a06357 305 Gene3D G3DSA:3.40.190.10 91 178 1.6E-10 T 29-03-2018 CDC59_RS12760 2086d43f1fdf169174119d1dd1a06357 305 Gene3D G3DSA:1.10.10.10 1 83 2.0E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS12760 2086d43f1fdf169174119d1dd1a06357 305 SUPERFAMILY SSF46785 1 83 4.22E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS12760 2086d43f1fdf169174119d1dd1a06357 305 Pfam PF03466 LysR substrate binding domain 87 292 4.5E-34 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS12760 2086d43f1fdf169174119d1dd1a06357 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 5.2E-21 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS12760 2086d43f1fdf169174119d1dd1a06357 305 Gene3D G3DSA:3.40.190.10 179 265 4.2E-16 T 29-03-2018 CDC59_RS12760 2086d43f1fdf169174119d1dd1a06357 305 SUPERFAMILY SSF53850 88 293 1.7E-32 T 29-03-2018 CDC59_RS11165 755a2d15d358d12b69b568829ea2130b 498 SUPERFAMILY SSF51905 51 441 1.81E-29 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS11165 755a2d15d358d12b69b568829ea2130b 498 Gene3D G3DSA:3.50.50.60 229 460 2.2E-14 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS11165 755a2d15d358d12b69b568829ea2130b 498 Gene3D G3DSA:3.50.50.60 49 228 6.8E-19 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS11165 755a2d15d358d12b69b568829ea2130b 498 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 49 269 1.9E-15 T 29-03-2018 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase CDC59_RS11165 755a2d15d358d12b69b568829ea2130b 498 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 52 71 6.0E-7 T 29-03-2018 CDC59_RS11165 755a2d15d358d12b69b568829ea2130b 498 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 233 251 6.0E-7 T 29-03-2018 CDC59_RS11165 755a2d15d358d12b69b568829ea2130b 498 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 188 206 6.0E-7 T 29-03-2018 CDC59_RS11165 755a2d15d358d12b69b568829ea2130b 498 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 51 73 3.0E-9 T 29-03-2018 CDC59_RS11165 755a2d15d358d12b69b568829ea2130b 498 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 191 200 3.0E-9 T 29-03-2018 CDC59_RS11165 755a2d15d358d12b69b568829ea2130b 498 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 233 258 3.0E-9 T 29-03-2018 CDC59_RS16805 330ace2028b1d86808b95ea9ea29a190 515 Gene3D G3DSA:1.10.287.1060 239 323 0.021 T 29-03-2018 CDC59_RS16805 330ace2028b1d86808b95ea9ea29a190 515 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 187 207 1.9E-61 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS16805 330ace2028b1d86808b95ea9ea29a190 515 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 4 29 1.9E-61 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS16805 330ace2028b1d86808b95ea9ea29a190 515 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 392 421 1.9E-61 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS16805 330ace2028b1d86808b95ea9ea29a190 515 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 363 390 1.9E-61 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS16805 330ace2028b1d86808b95ea9ea29a190 515 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 60 75 1.9E-61 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS16805 330ace2028b1d86808b95ea9ea29a190 515 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 440 469 1.9E-61 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS16805 330ace2028b1d86808b95ea9ea29a190 515 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 286 315 1.9E-61 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS16805 330ace2028b1d86808b95ea9ea29a190 515 Pfam PF02203 Tar ligand binding domain homologue 2 172 3.6E-43 T 29-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 CDC59_RS16805 330ace2028b1d86808b95ea9ea29a190 515 SUPERFAMILY SSF47170 44 160 4.19E-7 T 29-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 CDC59_RS16805 330ace2028b1d86808b95ea9ea29a190 515 SUPERFAMILY SSF58104 232 513 4.58E-75 T 29-03-2018 CDC59_RS16805 330ace2028b1d86808b95ea9ea29a190 515 SMART SM00283 265 512 3.2E-91 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CDC59_RS16805 330ace2028b1d86808b95ea9ea29a190 515 Gene3D G3DSA:1.20.120.30 23 186 4.6E-28 T 29-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain CDC59_RS16805 330ace2028b1d86808b95ea9ea29a190 515 Gene3D G3DSA:1.10.287.950 324 515 3.9E-49 T 29-03-2018 CDC59_RS16805 330ace2028b1d86808b95ea9ea29a190 515 SMART SM00304 212 264 7.4E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CDC59_RS16805 330ace2028b1d86808b95ea9ea29a190 515 Pfam PF00672 HAMP domain 212 260 9.6E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CDC59_RS16805 330ace2028b1d86808b95ea9ea29a190 515 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 324 480 9.3E-56 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CDC59_RS02735 4d50fa3e2a70573318b07a646446fe9b 801 Gene3D G3DSA:2.170.130.10 113 263 6.8E-26 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CDC59_RS02735 4d50fa3e2a70573318b07a646446fe9b 801 Pfam PF07715 TonB-dependent Receptor Plug Domain 152 251 1.1E-18 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CDC59_RS02735 4d50fa3e2a70573318b07a646446fe9b 801 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 153 799 1.7E-114 T 29-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 CDC59_RS02735 4d50fa3e2a70573318b07a646446fe9b 801 SMART SM00965 57 108 1.6E-14 T 29-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 CDC59_RS02735 4d50fa3e2a70573318b07a646446fe9b 801 Gene3D G3DSA:2.40.170.20 264 801 3.0E-89 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CDC59_RS02735 4d50fa3e2a70573318b07a646446fe9b 801 SUPERFAMILY SSF56935 141 801 2.38E-136 T 29-03-2018 CDC59_RS02735 4d50fa3e2a70573318b07a646446fe9b 801 Pfam PF07660 Secretin and TonB N terminus short domain 57 107 2.0E-8 T 29-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 CDC59_RS02735 4d50fa3e2a70573318b07a646446fe9b 801 Pfam PF00593 TonB dependent receptor 324 799 6.9E-66 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CDC59_RS16270 3cf3172ddd332582140746909bc37282 703 Gene3D G3DSA:2.40.170.20 178 703 6.3E-84 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CDC59_RS16270 3cf3172ddd332582140746909bc37282 703 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 87 703 1.4E-91 T 29-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 CDC59_RS16270 3cf3172ddd332582140746909bc37282 703 SUPERFAMILY SSF56935 53 703 1.95E-127 T 29-03-2018 CDC59_RS16270 3cf3172ddd332582140746909bc37282 703 Pfam PF00593 TonB dependent receptor 248 702 1.3E-59 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CDC59_RS16270 3cf3172ddd332582140746909bc37282 703 Gene3D G3DSA:2.170.130.10 25 172 3.4E-21 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CDC59_RS16270 3cf3172ddd332582140746909bc37282 703 Pfam PF07715 TonB-dependent Receptor Plug Domain 61 165 1.4E-16 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CDC59_RS06990 ae8339012619b1e33b20090ab0f127e4 313 SUPERFAMILY SSF103481 61 146 5.89E-9 T 29-03-2018 CDC59_RS06990 ae8339012619b1e33b20090ab0f127e4 313 SUPERFAMILY SSF103481 208 303 5.1E-11 T 29-03-2018 CDC59_RS06990 ae8339012619b1e33b20090ab0f127e4 313 Pfam PF00892 EamA-like transporter family 19 146 6.7E-12 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CDC59_RS06990 ae8339012619b1e33b20090ab0f127e4 313 Pfam PF00892 EamA-like transporter family 166 303 2.2E-16 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CDC59_RS23600 f683c6d202d4104ef71491fc1671abd7 561 Gene3D G3DSA:2.60.40.290 472 561 1.3E-16 T 29-03-2018 CDC59_RS23600 f683c6d202d4104ef71491fc1671abd7 561 PIRSF PIRSF001100 462 546 1200.0 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CDC59_RS23600 f683c6d202d4104ef71491fc1671abd7 561 PIRSF PIRSF001100 8 460 1.0E-88 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CDC59_RS23600 f683c6d202d4104ef71491fc1671abd7 561 SUPERFAMILY SSF49384 475 559 1.19E-17 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 CDC59_RS23600 f683c6d202d4104ef71491fc1671abd7 561 Pfam PF01341 Glycosyl hydrolases family 6 59 412 1.8E-94 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CDC59_RS23600 f683c6d202d4104ef71491fc1671abd7 561 SUPERFAMILY SSF51989 38 460 7.59E-116 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CDC59_RS23600 f683c6d202d4104ef71491fc1671abd7 561 PRINTS PR00733 Glycosyl hydrolase family 6 signature 155 170 1.3E-34 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CDC59_RS23600 f683c6d202d4104ef71491fc1671abd7 561 PRINTS PR00733 Glycosyl hydrolase family 6 signature 67 86 1.3E-34 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CDC59_RS23600 f683c6d202d4104ef71491fc1671abd7 561 PRINTS PR00733 Glycosyl hydrolase family 6 signature 389 403 1.3E-34 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CDC59_RS23600 f683c6d202d4104ef71491fc1671abd7 561 PRINTS PR00733 Glycosyl hydrolase family 6 signature 366 386 1.3E-34 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CDC59_RS23600 f683c6d202d4104ef71491fc1671abd7 561 PRINTS PR00733 Glycosyl hydrolase family 6 signature 262 272 1.3E-34 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CDC59_RS23600 f683c6d202d4104ef71491fc1671abd7 561 PRINTS PR00733 Glycosyl hydrolase family 6 signature 326 339 1.3E-34 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CDC59_RS23600 f683c6d202d4104ef71491fc1671abd7 561 PRINTS PR00733 Glycosyl hydrolase family 6 signature 121 134 1.3E-34 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CDC59_RS23600 f683c6d202d4104ef71491fc1671abd7 561 PRINTS PR00733 Glycosyl hydrolase family 6 signature 222 235 1.3E-34 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CDC59_RS23600 f683c6d202d4104ef71491fc1671abd7 561 Pfam PF00553 Cellulose binding domain 485 559 3.9E-13 T 29-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CDC59_RS23600 f683c6d202d4104ef71491fc1671abd7 561 Gene3D G3DSA:3.20.20.40 38 460 2.1E-133 T 29-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CDC59_RS23600 f683c6d202d4104ef71491fc1671abd7 561 SMART SM00637 481 560 2.3E-5 T 29-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CDC59_RS22940 3344c33b968cd4b45b15943d796d8930 1068 SUPERFAMILY SSF82693 137 182 4.92E-14 T 29-03-2018 CDC59_RS22940 3344c33b968cd4b45b15943d796d8930 1068 SUPERFAMILY SSF82693 268 324 4.92E-14 T 29-03-2018 CDC59_RS22940 3344c33b968cd4b45b15943d796d8930 1068 SUPERFAMILY SSF82866 290 489 1.12E-39 T 29-03-2018 CDC59_RS22940 3344c33b968cd4b45b15943d796d8930 1068 Gene3D G3DSA:3.30.2090.10 181 268 9.9E-15 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS22940 3344c33b968cd4b45b15943d796d8930 1068 Gene3D G3DSA:3.30.2090.10 727 847 4.4E-9 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS22940 3344c33b968cd4b45b15943d796d8930 1068 Gene3D G3DSA:3.30.70.1430 567 678 6.2E-11 T 29-03-2018 CDC59_RS22940 3344c33b968cd4b45b15943d796d8930 1068 SUPERFAMILY SSF82866 825 1050 1.11E-50 T 29-03-2018 CDC59_RS22940 3344c33b968cd4b45b15943d796d8930 1068 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 3.8E-38 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS22940 3344c33b968cd4b45b15943d796d8930 1068 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 3.8E-38 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS22940 3344c33b968cd4b45b15943d796d8930 1068 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 3.8E-38 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS22940 3344c33b968cd4b45b15943d796d8930 1068 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 3.8E-38 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS22940 3344c33b968cd4b45b15943d796d8930 1068 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 3.8E-38 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS22940 3344c33b968cd4b45b15943d796d8930 1068 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 3.8E-38 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS22940 3344c33b968cd4b45b15943d796d8930 1068 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 3.8E-38 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS22940 3344c33b968cd4b45b15943d796d8930 1068 PRINTS PR00702 Acriflavin resistance protein family signature 552 569 3.8E-38 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS22940 3344c33b968cd4b45b15943d796d8930 1068 SUPERFAMILY SSF82714 183 266 1.05E-15 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS22940 3344c33b968cd4b45b15943d796d8930 1068 Pfam PF00873 AcrB/AcrD/AcrF family 3 1047 2.4E-206 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS22940 3344c33b968cd4b45b15943d796d8930 1068 SUPERFAMILY SSF82693 40 135 1.1E-16 T 29-03-2018 CDC59_RS22940 3344c33b968cd4b45b15943d796d8930 1068 Gene3D G3DSA:3.30.70.1430 40 141 3.7E-18 T 29-03-2018 CDC59_RS22940 3344c33b968cd4b45b15943d796d8930 1068 Gene3D G3DSA:1.20.1640.10 848 1050 3.6E-32 T 29-03-2018 CDC59_RS22940 3344c33b968cd4b45b15943d796d8930 1068 Gene3D G3DSA:1.20.1640.10 281 500 6.1E-38 T 29-03-2018 CDC59_RS21940 8522d331d8e9c3a33a3b8ef09f7d7405 469 SUPERFAMILY SSF141868 206 452 6.67E-64 T 29-03-2018 IPR001633 EAL domain CDC59_RS21940 8522d331d8e9c3a33a3b8ef09f7d7405 469 SMART SM00052 199 452 3.3E-55 T 29-03-2018 IPR001633 EAL domain CDC59_RS21940 8522d331d8e9c3a33a3b8ef09f7d7405 469 Gene3D G3DSA:3.30.70.270 11 188 8.1E-24 T 29-03-2018 CDC59_RS21940 8522d331d8e9c3a33a3b8ef09f7d7405 469 Gene3D G3DSA:3.20.20.450 189 463 1.1E-72 T 29-03-2018 IPR001633 EAL domain CDC59_RS21940 8522d331d8e9c3a33a3b8ef09f7d7405 469 Pfam PF00563 EAL domain 205 447 1.1E-58 T 29-03-2018 IPR001633 EAL domain CDC59_RS21940 8522d331d8e9c3a33a3b8ef09f7d7405 469 Pfam PF00990 Diguanylate cyclase, GGDEF domain 12 169 7.3E-15 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS21940 8522d331d8e9c3a33a3b8ef09f7d7405 469 SMART SM00267 1 175 1.1E-6 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS21940 8522d331d8e9c3a33a3b8ef09f7d7405 469 SUPERFAMILY SSF55073 16 174 3.45E-19 T 29-03-2018 IPR029787 Nucleotide cyclase CDC59_RS03105 b4dc86573e204d0c6a7e2c90d87544fe 514 SUPERFAMILY SSF53623 116 351 3.05E-73 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CDC59_RS03105 b4dc86573e204d0c6a7e2c90d87544fe 514 Gene3D G3DSA:3.40.1190.10 115 355 1.9E-53 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CDC59_RS03105 b4dc86573e204d0c6a7e2c90d87544fe 514 Pfam PF08245 Mur ligase middle domain 123 331 5.0E-51 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CDC59_RS03105 b4dc86573e204d0c6a7e2c90d87544fe 514 Gene3D G3DSA:3.90.190.20 356 511 3.8E-49 T 29-03-2018 CDC59_RS03105 b4dc86573e204d0c6a7e2c90d87544fe 514 Gene3D G3DSA:3.40.1390.10 23 112 2.7E-14 T 29-03-2018 CDC59_RS03105 b4dc86573e204d0c6a7e2c90d87544fe 514 SUPERFAMILY SSF63418 32 110 3.01E-13 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CDC59_RS03105 b4dc86573e204d0c6a7e2c90d87544fe 514 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 32 507 1.5E-144 T 29-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 CDC59_RS03105 b4dc86573e204d0c6a7e2c90d87544fe 514 SUPERFAMILY SSF53244 352 508 6.11E-48 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CDC59_RS03105 b4dc86573e204d0c6a7e2c90d87544fe 514 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 14 507 33.703 T 29-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 CDC59_RS03105 b4dc86573e204d0c6a7e2c90d87544fe 514 Pfam PF02875 Mur ligase family, glutamate ligase domain 352 440 4.7E-23 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CDC59_RS00470 60989df7ed8b57e5f5441c248add22ef 491 SMART SM00388 261 326 1.2E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS00470 60989df7ed8b57e5f5441c248add22ef 491 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 373 477 8.1E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS00470 60989df7ed8b57e5f5441c248add22ef 491 PRINTS PR00344 Bacterial sensor protein C-terminal signature 425 435 2.0E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS00470 60989df7ed8b57e5f5441c248add22ef 491 PRINTS PR00344 Bacterial sensor protein C-terminal signature 407 421 2.0E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS00470 60989df7ed8b57e5f5441c248add22ef 491 PRINTS PR00344 Bacterial sensor protein C-terminal signature 439 457 2.0E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS00470 60989df7ed8b57e5f5441c248add22ef 491 Gene3D G3DSA:3.30.565.10 328 491 6.7E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS00470 60989df7ed8b57e5f5441c248add22ef 491 Pfam PF00512 His Kinase A (phospho-acceptor) domain 262 325 1.2E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS00470 60989df7ed8b57e5f5441c248add22ef 491 Gene3D G3DSA:1.10.287.130 247 322 2.3E-10 T 29-03-2018 CDC59_RS00470 60989df7ed8b57e5f5441c248add22ef 491 Pfam PF08521 Two-component sensor kinase N-terminal 29 184 1.6E-26 T 29-03-2018 IPR013727 Two-component sensor kinase, N-terminal CDC59_RS00470 60989df7ed8b57e5f5441c248add22ef 491 SMART SM00387 370 480 1.9E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS00470 60989df7ed8b57e5f5441c248add22ef 491 Gene3D G3DSA:1.20.5.1040 15 67 5.0E-4 T 29-03-2018 CDC59_RS00470 60989df7ed8b57e5f5441c248add22ef 491 SUPERFAMILY SSF55874 315 478 3.27E-40 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS00470 60989df7ed8b57e5f5441c248add22ef 491 SUPERFAMILY SSF47384 244 325 4.32E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS13765 59d5ffaabd4529bfc50d41ab26148544 423 Gene3D G3DSA:3.40.50.620 24 246 4.9E-58 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDC59_RS13765 59d5ffaabd4529bfc50d41ab26148544 423 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 33 421 1.6E-116 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CDC59_RS13765 59d5ffaabd4529bfc50d41ab26148544 423 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 189 204 1.4E-25 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CDC59_RS13765 59d5ffaabd4529bfc50d41ab26148544 423 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 206 228 1.4E-25 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CDC59_RS13765 59d5ffaabd4529bfc50d41ab26148544 423 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 74 96 1.4E-25 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CDC59_RS13765 59d5ffaabd4529bfc50d41ab26148544 423 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 239 251 1.4E-25 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CDC59_RS13765 59d5ffaabd4529bfc50d41ab26148544 423 SMART SM00363 362 423 0.0032 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CDC59_RS13765 59d5ffaabd4529bfc50d41ab26148544 423 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 70 80 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDC59_RS13765 59d5ffaabd4529bfc50d41ab26148544 423 SUPERFAMILY SSF52374 36 340 3.38E-88 T 29-03-2018 CDC59_RS13765 59d5ffaabd4529bfc50d41ab26148544 423 Pfam PF01479 S4 domain 364 407 1.7E-7 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CDC59_RS13765 59d5ffaabd4529bfc50d41ab26148544 423 SUPERFAMILY SSF55174 344 419 2.22E-19 T 29-03-2018 CDC59_RS13765 59d5ffaabd4529bfc50d41ab26148544 423 Hamap MF_02007 Tyrosine--tRNA ligase [tyrS]. 26 422 46.962 T 29-03-2018 IPR024108 Tyrosine-tRNA ligase, bacterial-type, type 2 GO:0004831 KEGG: 00970+6.1.1.1 CDC59_RS13765 59d5ffaabd4529bfc50d41ab26148544 423 Pfam PF00579 tRNA synthetases class I (W and Y) 61 341 4.9E-72 T 29-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDC59_RS13765 59d5ffaabd4529bfc50d41ab26148544 423 Gene3D G3DSA:3.10.290.10 347 421 1.9E-19 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CDC59_RS13765 59d5ffaabd4529bfc50d41ab26148544 423 Gene3D G3DSA:1.10.240.10 247 346 7.8E-25 T 29-03-2018 CDC59_RS19105 63aeb1582f33cd4fc405279fdef3f186 518 Gene3D G3DSA:3.40.50.1400 105 233 1.1E-24 T 29-03-2018 CDC59_RS19105 63aeb1582f33cd4fc405279fdef3f186 518 Gene3D G3DSA:3.40.50.1400 1 104 5.5E-25 T 29-03-2018 CDC59_RS19105 63aeb1582f33cd4fc405279fdef3f186 518 SUPERFAMILY SSF53800 1 247 2.73E-51 T 29-03-2018 CDC59_RS19105 63aeb1582f33cd4fc405279fdef3f186 518 SUPERFAMILY SSF63965 301 502 7.85E-66 T 29-03-2018 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 CDC59_RS19105 63aeb1582f33cd4fc405279fdef3f186 518 Pfam PF01903 CbiX 6 110 1.8E-23 T 29-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 CDC59_RS19105 63aeb1582f33cd4fc405279fdef3f186 518 Pfam PF01903 CbiX 136 239 1.3E-21 T 29-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 CDC59_RS19105 63aeb1582f33cd4fc405279fdef3f186 518 Pfam PF02570 Precorrin-8X methylmutase 306 500 3.9E-66 T 29-03-2018 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 CDC59_RS19105 63aeb1582f33cd4fc405279fdef3f186 518 Gene3D G3DSA:3.40.50.10230 301 517 6.1E-72 T 29-03-2018 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 CDC59_RS02240 5e4b1fb41c133fd0140624876aca527b 206 SUPERFAMILY SSF52166 1 205 5.1E-67 T 29-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CDC59_RS02240 5e4b1fb41c133fd0140624876aca527b 206 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 18 203 2.1E-68 T 29-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS02240 5e4b1fb41c133fd0140624876aca527b 206 Gene3D G3DSA:3.40.1370.10 146 204 1.7E-10 T 29-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CDC59_RS02240 5e4b1fb41c133fd0140624876aca527b 206 Gene3D G3DSA:3.40.1370.10 1 145 1.8E-44 T 29-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CDC59_RS02240 5e4b1fb41c133fd0140624876aca527b 206 Pfam PF00573 Ribosomal protein L4/L1 family 18 203 7.3E-61 T 29-03-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 CDC59_RS02240 5e4b1fb41c133fd0140624876aca527b 206 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 8 206 30.846 T 29-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS07690 7ec799464e6ba5f60837e0e334f08034 427 Pfam PF00113 Enolase, C-terminal TIM barrel domain 141 424 8.5E-132 T 29-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CDC59_RS07690 7ec799464e6ba5f60837e0e334f08034 427 Gene3D G3DSA:3.20.20.120 128 427 5.7E-102 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CDC59_RS07690 7ec799464e6ba5f60837e0e334f08034 427 SMART SM01193 4 134 2.1E-95 T 29-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CDC59_RS07690 7ec799464e6ba5f60837e0e334f08034 427 SUPERFAMILY SSF51604 139 426 5.94E-128 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CDC59_RS07690 7ec799464e6ba5f60837e0e334f08034 427 ProSitePatterns PS00164 Enolase signature. 334 347 - T 29-03-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDC59_RS07690 7ec799464e6ba5f60837e0e334f08034 427 PRINTS PR00148 Enolase signature 363 380 4.7E-44 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CDC59_RS07690 7ec799464e6ba5f60837e0e334f08034 427 PRINTS PR00148 Enolase signature 161 174 4.7E-44 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CDC59_RS07690 7ec799464e6ba5f60837e0e334f08034 427 PRINTS PR00148 Enolase signature 37 51 4.7E-44 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CDC59_RS07690 7ec799464e6ba5f60837e0e334f08034 427 PRINTS PR00148 Enolase signature 334 348 4.7E-44 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CDC59_RS07690 7ec799464e6ba5f60837e0e334f08034 427 PRINTS PR00148 Enolase signature 107 123 4.7E-44 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CDC59_RS07690 7ec799464e6ba5f60837e0e334f08034 427 PRINTS PR00148 Enolase signature 311 322 4.7E-44 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CDC59_RS07690 7ec799464e6ba5f60837e0e334f08034 427 SUPERFAMILY SSF54826 4 136 5.05E-56 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CDC59_RS07690 7ec799464e6ba5f60837e0e334f08034 427 Pfam PF03952 Enolase, N-terminal domain 4 133 1.3E-58 T 29-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CDC59_RS07690 7ec799464e6ba5f60837e0e334f08034 427 Gene3D G3DSA:3.30.390.10 3 127 1.0E-52 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CDC59_RS07690 7ec799464e6ba5f60837e0e334f08034 427 Hamap MF_00318 Enolase [eno]. 2 411 44.81 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CDC59_RS07690 7ec799464e6ba5f60837e0e334f08034 427 SMART SM01192 139 425 6.8E-221 T 29-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CDC59_RS07690 7ec799464e6ba5f60837e0e334f08034 427 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 425 2.5E-209 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CDC59_RS07690 7ec799464e6ba5f60837e0e334f08034 427 PIRSF PIRSF001400 1 425 2.6E-189 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CDC59_RS14815 d2753b3109fc00584e1e6b2ac8f898b6 290 Gene3D G3DSA:1.10.10.10 13 90 1.4E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS14815 d2753b3109fc00584e1e6b2ac8f898b6 290 SUPERFAMILY SSF55781 101 282 3.53E-31 T 29-03-2018 IPR029016 GAF domain-like CDC59_RS14815 d2753b3109fc00584e1e6b2ac8f898b6 290 Pfam PF09339 IclR helix-turn-helix domain 32 83 3.0E-13 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CDC59_RS14815 d2753b3109fc00584e1e6b2ac8f898b6 290 SMART SM00346 30 119 1.6E-15 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CDC59_RS14815 d2753b3109fc00584e1e6b2ac8f898b6 290 Gene3D G3DSA:3.30.450.40 102 285 2.8E-38 T 29-03-2018 IPR029016 GAF domain-like CDC59_RS14815 d2753b3109fc00584e1e6b2ac8f898b6 290 SUPERFAMILY SSF46785 30 102 4.21E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS14815 d2753b3109fc00584e1e6b2ac8f898b6 290 Pfam PF01614 Bacterial transcriptional regulator 148 249 1.9E-4 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CDC59_RS07080 cfcbc242816fcc485af09b5f6dd21d04 214 PIRSF PIRSF001435 1 210 2.0E-50 T 29-03-2018 CDC59_RS07080 cfcbc242816fcc485af09b5f6dd21d04 214 Pfam PF00633 Helix-hairpin-helix motif 100 127 7.9E-8 T 29-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 CDC59_RS07080 cfcbc242816fcc485af09b5f6dd21d04 214 SMART SM00478 38 185 1.8E-53 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CDC59_RS07080 cfcbc242816fcc485af09b5f6dd21d04 214 Gene3D G3DSA:1.10.340.30 17 117 1.3E-22 T 29-03-2018 CDC59_RS07080 cfcbc242816fcc485af09b5f6dd21d04 214 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 34 168 3.6E-17 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CDC59_RS07080 cfcbc242816fcc485af09b5f6dd21d04 214 TIGRFAM TIGR01083 nth: endonuclease III 5 194 9.0E-85 T 29-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 CDC59_RS07080 cfcbc242816fcc485af09b5f6dd21d04 214 Gene3D G3DSA:1.10.1670.10 118 213 4.0E-29 T 29-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CDC59_RS07080 cfcbc242816fcc485af09b5f6dd21d04 214 Hamap MF_00942 Endonuclease III [nth]. 1 209 36.954 T 29-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 CDC59_RS07080 cfcbc242816fcc485af09b5f6dd21d04 214 SUPERFAMILY SSF48150 2 208 1.43E-70 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CDC59_RS07080 cfcbc242816fcc485af09b5f6dd21d04 214 ProSitePatterns PS01155 Endonuclease III family signature. 102 131 - T 29-03-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 CDC59_RS20790 f0c1585641d790bf0aca0b7effe5cd8d 215 SUPERFAMILY SSF51161 7 212 3.47E-35 T 29-03-2018 IPR011004 Trimeric LpxA-like CDC59_RS20790 f0c1585641d790bf0aca0b7effe5cd8d 215 TIGRFAM TIGR03570 NeuD_NnaD: sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family 6 211 1.9E-49 T 29-03-2018 IPR020019 Sialic acid O-acyltransferase NeuD-like CDC59_RS20790 f0c1585641d790bf0aca0b7effe5cd8d 215 Gene3D G3DSA:2.160.10.10 91 215 3.4E-31 T 29-03-2018 CDC59_RS20790 f0c1585641d790bf0aca0b7effe5cd8d 215 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 121 155 6.0E-6 T 29-03-2018 IPR001451 Hexapeptide repeat CDC59_RS20790 f0c1585641d790bf0aca0b7effe5cd8d 215 Gene3D G3DSA:3.40.50.20 2 90 7.9E-8 T 29-03-2018 CDC59_RS14495 a05b2470df28d7f9e8db5aaba001dee3 173 Gene3D G3DSA:3.10.420.10 3 158 4.5E-49 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 CDC59_RS14495 a05b2470df28d7f9e8db5aaba001dee3 173 SUPERFAMILY SSF54611 5 147 5.45E-50 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 CDC59_RS14495 a05b2470df28d7f9e8db5aaba001dee3 173 Hamap MF_00821 Protein-export protein SecB [secB]. 1 151 30.855 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 CDC59_RS14495 a05b2470df28d7f9e8db5aaba001dee3 173 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 103 125 4.1E-28 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 CDC59_RS14495 a05b2470df28d7f9e8db5aaba001dee3 173 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 129 147 4.1E-28 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 CDC59_RS14495 a05b2470df28d7f9e8db5aaba001dee3 173 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 79 99 4.1E-28 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 CDC59_RS14495 a05b2470df28d7f9e8db5aaba001dee3 173 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 19 36 4.1E-28 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 CDC59_RS14495 a05b2470df28d7f9e8db5aaba001dee3 173 Pfam PF02556 Preprotein translocase subunit SecB 11 148 4.8E-53 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 CDC59_RS14495 a05b2470df28d7f9e8db5aaba001dee3 173 TIGRFAM TIGR00809 secB: protein-export chaperone SecB 13 148 8.8E-47 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 CDC59_RS07705 540a2fd51c29e8eec927963f1bd2a520 338 Pfam PF01430 Hsp33 protein 3 313 1.1E-81 T 29-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 CDC59_RS07705 540a2fd51c29e8eec927963f1bd2a520 338 SUPERFAMILY SSF118352 265 322 2.75E-17 T 29-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 CDC59_RS07705 540a2fd51c29e8eec927963f1bd2a520 338 SUPERFAMILY SSF64397 3 188 3.14E-58 T 29-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 CDC59_RS07705 540a2fd51c29e8eec927963f1bd2a520 338 SUPERFAMILY SSF64397 216 271 3.14E-58 T 29-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 CDC59_RS07705 540a2fd51c29e8eec927963f1bd2a520 338 PIRSF PIRSF005261 1 325 1.3E-67 T 29-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 CDC59_RS07705 540a2fd51c29e8eec927963f1bd2a520 338 Gene3D G3DSA:3.55.30.10 1 184 9.0E-59 T 29-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 CDC59_RS07705 540a2fd51c29e8eec927963f1bd2a520 338 Gene3D G3DSA:1.10.287.480 216 263 7.9E-15 T 29-03-2018 IPR023212 Heat shock protein Hsp33, helix hairpin bin domain CDC59_RS07705 540a2fd51c29e8eec927963f1bd2a520 338 Gene3D G3DSA:3.90.1280.10 266 321 8.6E-22 T 29-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 CDC59_RS22870 9d3d2aaaf3c73f01ac441b5dacaf489c 223 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 109 1.3E-20 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CDC59_RS22870 9d3d2aaaf3c73f01ac441b5dacaf489c 223 SUPERFAMILY SSF161098 13 200 3.53E-34 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS22870 9d3d2aaaf3c73f01ac441b5dacaf489c 223 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 31 211 3.3E-17 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS22870 9d3d2aaaf3c73f01ac441b5dacaf489c 223 Gene3D G3DSA:1.10.3720.10 2 218 8.8E-36 T 29-03-2018 CDC59_RS00980 883addf78b07e9297ba98df5755c337e 982 Pfam PF02347 Glycine cleavage system P-protein 32 462 8.5E-173 T 29-03-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CDC59_RS00980 883addf78b07e9297ba98df5755c337e 982 Pfam PF02347 Glycine cleavage system P-protein 498 759 1.3E-11 T 29-03-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CDC59_RS00980 883addf78b07e9297ba98df5755c337e 982 Gene3D G3DSA:3.40.640.10 538 794 5.8E-41 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDC59_RS00980 883addf78b07e9297ba98df5755c337e 982 TIGRFAM TIGR00461 gcvP: glycine dehydrogenase 33 973 0.0 T 29-03-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CDC59_RS00980 883addf78b07e9297ba98df5755c337e 982 Gene3D G3DSA:3.90.1150.10 795 928 1.2E-42 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS00980 883addf78b07e9297ba98df5755c337e 982 Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. 24 979 25.959 T 29-03-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CDC59_RS00980 883addf78b07e9297ba98df5755c337e 982 Gene3D G3DSA:3.40.640.10 114 363 5.4E-34 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDC59_RS00980 883addf78b07e9297ba98df5755c337e 982 SUPERFAMILY SSF53383 483 909 2.75E-98 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS00980 883addf78b07e9297ba98df5755c337e 982 SUPERFAMILY SSF53383 952 974 2.75E-98 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS00980 883addf78b07e9297ba98df5755c337e 982 SUPERFAMILY SSF53383 33 465 3.08E-99 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS00980 883addf78b07e9297ba98df5755c337e 982 Gene3D G3DSA:3.90.1150.10 364 467 9.7E-28 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS14690 33512a7fa1b3842f7285f713f7cc9a4a 465 SMART SM00490 260 341 1.5E-24 T 29-03-2018 IPR001650 Helicase, C-terminal CDC59_RS14690 33512a7fa1b3842f7285f713f7cc9a4a 465 Gene3D G3DSA:3.40.50.300 225 460 2.1E-40 T 29-03-2018 CDC59_RS14690 33512a7fa1b3842f7285f713f7cc9a4a 465 Pfam PF03880 DbpA RNA binding domain 391 461 4.7E-23 T 29-03-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain CDC59_RS14690 33512a7fa1b3842f7285f713f7cc9a4a 465 Pfam PF00270 DEAD/DEAH box helicase 32 198 1.6E-46 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CDC59_RS14690 33512a7fa1b3842f7285f713f7cc9a4a 465 Pfam PF00271 Helicase conserved C-terminal domain 237 340 1.4E-25 T 29-03-2018 IPR001650 Helicase, C-terminal CDC59_RS14690 33512a7fa1b3842f7285f713f7cc9a4a 465 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 156 164 - T 29-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site CDC59_RS14690 33512a7fa1b3842f7285f713f7cc9a4a 465 SUPERFAMILY SSF52540 77 356 2.91E-69 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS14690 33512a7fa1b3842f7285f713f7cc9a4a 465 Gene3D G3DSA:3.40.50.300 9 224 5.7E-60 T 29-03-2018 CDC59_RS14690 33512a7fa1b3842f7285f713f7cc9a4a 465 SMART SM00487 27 224 1.4E-58 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CDC59_RS23330 ba0ebcd8b6192e914f66554609ea462c 96 Gene3D G3DSA:4.10.430.10 63 95 9.0E-15 T 29-03-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 CDC59_RS23330 ba0ebcd8b6192e914f66554609ea462c 96 SUPERFAMILY SSF81273 60 95 1.18E-9 T 29-03-2018 CDC59_RS23330 ba0ebcd8b6192e914f66554609ea462c 96 Pfam PF00816 H-NS histone family 7 88 1.0E-21 T 29-03-2018 IPR001801 Histone-like protein H-NS GO:0003677|GO:0005622|GO:0006355 CDC59_RS23330 ba0ebcd8b6192e914f66554609ea462c 96 SMART SM00528 57 95 1.2E-10 T 29-03-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 CDC59_RS07450 6cb5c027a3fff30f62320e02a3df807e 240 SUPERFAMILY SSF52172 1 130 3.52E-8 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS07450 6cb5c027a3fff30f62320e02a3df807e 240 SMART SM00862 149 225 1.3E-15 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDC59_RS07450 6cb5c027a3fff30f62320e02a3df807e 240 SUPERFAMILY SSF46894 127 226 1.93E-20 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CDC59_RS07450 6cb5c027a3fff30f62320e02a3df807e 240 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 225 1.5E-15 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDC59_RS07450 6cb5c027a3fff30f62320e02a3df807e 240 Gene3D G3DSA:1.10.10.10 127 229 1.7E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS07450 6cb5c027a3fff30f62320e02a3df807e 240 Gene3D G3DSA:3.40.50.2300 1 126 3.1E-11 T 29-03-2018 CDC59_RS12735 e2d2e6033b90366319057caf243011ac 449 Gene3D G3DSA:1.10.760.10 41 220 3.7E-25 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS12735 e2d2e6033b90366319057caf243011ac 449 Pfam PF03150 Di-haem cytochrome c peroxidase 53 231 6.9E-30 T 29-03-2018 IPR004852 Di-haem cytochrome c peroxidase GO:0016491|GO:0055114 CDC59_RS12735 e2d2e6033b90366319057caf243011ac 449 Gene3D G3DSA:1.10.760.10 221 428 2.5E-30 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS12735 e2d2e6033b90366319057caf243011ac 449 SUPERFAMILY SSF46626 315 410 7.17E-29 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS12735 e2d2e6033b90366319057caf243011ac 449 SUPERFAMILY SSF46626 208 283 7.17E-29 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS12735 e2d2e6033b90366319057caf243011ac 449 Pfam PF00034 Cytochrome c 240 409 2.6E-5 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS12735 e2d2e6033b90366319057caf243011ac 449 SUPERFAMILY SSF46626 42 214 1.96E-23 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS18810 4a5e03e04fa404c580b66a9fc8b9365e 492 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 364 469 1.3E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS18810 4a5e03e04fa404c580b66a9fc8b9365e 492 SMART SM00388 244 309 1.5E-7 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS18810 4a5e03e04fa404c580b66a9fc8b9365e 492 Pfam PF00512 His Kinase A (phospho-acceptor) domain 246 308 8.3E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS18810 4a5e03e04fa404c580b66a9fc8b9365e 492 SUPERFAMILY SSF47384 227 309 3.73E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS18810 4a5e03e04fa404c580b66a9fc8b9365e 492 Gene3D G3DSA:1.10.287.130 234 305 2.8E-10 T 29-03-2018 CDC59_RS18810 4a5e03e04fa404c580b66a9fc8b9365e 492 SMART SM00387 357 471 2.1E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS18810 4a5e03e04fa404c580b66a9fc8b9365e 492 SUPERFAMILY SSF55874 299 472 2.49E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS18810 4a5e03e04fa404c580b66a9fc8b9365e 492 Gene3D G3DSA:3.30.565.10 319 471 6.3E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS18810 4a5e03e04fa404c580b66a9fc8b9365e 492 PRINTS PR00344 Bacterial sensor protein C-terminal signature 455 468 1.9E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS18810 4a5e03e04fa404c580b66a9fc8b9365e 492 PRINTS PR00344 Bacterial sensor protein C-terminal signature 416 426 1.9E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS18810 4a5e03e04fa404c580b66a9fc8b9365e 492 PRINTS PR00344 Bacterial sensor protein C-terminal signature 430 448 1.9E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS18810 4a5e03e04fa404c580b66a9fc8b9365e 492 PRINTS PR00344 Bacterial sensor protein C-terminal signature 398 412 1.9E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS09375 d1676249d62488b616889bd94bb16742 300 Pfam PF03466 LysR substrate binding domain 89 293 3.2E-45 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS09375 d1676249d62488b616889bd94bb16742 300 Gene3D G3DSA:3.40.190.10 174 261 3.4E-28 T 29-03-2018 CDC59_RS09375 d1676249d62488b616889bd94bb16742 300 SUPERFAMILY SSF46785 4 109 1.32E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS09375 d1676249d62488b616889bd94bb16742 300 Gene3D G3DSA:1.10.10.10 3 81 2.9E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS09375 d1676249d62488b616889bd94bb16742 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 63 4.0E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS09375 d1676249d62488b616889bd94bb16742 300 SUPERFAMILY SSF53850 87 297 1.14E-47 T 29-03-2018 CDC59_RS09375 d1676249d62488b616889bd94bb16742 300 Gene3D G3DSA:3.40.190.10 89 173 2.1E-16 T 29-03-2018 CDC59_RS18935 6eb5104b9a3a4628aeeb4ce87a08660c 680 Pfam PF00754 F5/8 type C domain 561 676 1.3E-12 T 29-03-2018 IPR000421 Coagulation factor 5/8 C-terminal domain CDC59_RS18935 6eb5104b9a3a4628aeeb4ce87a08660c 680 Pfam PF05593 RHS Repeat 253 289 3.4E-5 T 29-03-2018 IPR031325 RHS repeat CDC59_RS18935 6eb5104b9a3a4628aeeb4ce87a08660c 680 Pfam PF05593 RHS Repeat 415 450 2.6E-9 T 29-03-2018 IPR031325 RHS repeat CDC59_RS18935 6eb5104b9a3a4628aeeb4ce87a08660c 680 Pfam PF05593 RHS Repeat 74 110 1.0E-7 T 29-03-2018 IPR031325 RHS repeat CDC59_RS18935 6eb5104b9a3a4628aeeb4ce87a08660c 680 Pfam PF05593 RHS Repeat 482 519 1.6E-7 T 29-03-2018 IPR031325 RHS repeat CDC59_RS18935 6eb5104b9a3a4628aeeb4ce87a08660c 680 Pfam PF05593 RHS Repeat 116 153 2.0E-6 T 29-03-2018 IPR031325 RHS repeat CDC59_RS18935 6eb5104b9a3a4628aeeb4ce87a08660c 680 SUPERFAMILY SSF49785 561 679 3.97E-18 T 29-03-2018 IPR008979 Galactose-binding domain-like CDC59_RS18935 6eb5104b9a3a4628aeeb4ce87a08660c 680 Gene3D G3DSA:2.60.120.260 558 680 2.6E-17 T 29-03-2018 IPR008979 Galactose-binding domain-like CDC59_RS18935 6eb5104b9a3a4628aeeb4ce87a08660c 680 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 116 156 3.0E-8 T 29-03-2018 IPR006530 YD repeat CDC59_RS18935 6eb5104b9a3a4628aeeb4ce87a08660c 680 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 453 480 2.1E-4 T 29-03-2018 IPR006530 YD repeat CDC59_RS18935 6eb5104b9a3a4628aeeb4ce87a08660c 680 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 74 112 1.9E-6 T 29-03-2018 IPR006530 YD repeat CDC59_RS18935 6eb5104b9a3a4628aeeb4ce87a08660c 680 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 415 448 8.4E-5 T 29-03-2018 IPR006530 YD repeat CDC59_RS09340 f930e9be74ada530f5267974d724ecad 315 Gene3D G3DSA:3.40.190.10 102 191 1.0E-20 T 29-03-2018 CDC59_RS09340 f930e9be74ada530f5267974d724ecad 315 SUPERFAMILY SSF53850 105 313 2.78E-36 T 29-03-2018 CDC59_RS09340 f930e9be74ada530f5267974d724ecad 315 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 17 76 7.8E-21 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS09340 f930e9be74ada530f5267974d724ecad 315 Gene3D G3DSA:3.40.190.10 192 282 2.5E-13 T 29-03-2018 CDC59_RS09340 f930e9be74ada530f5267974d724ecad 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 43 2.8E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS09340 f930e9be74ada530f5267974d724ecad 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 53 2.8E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS09340 f930e9be74ada530f5267974d724ecad 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 53 64 2.8E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS09340 f930e9be74ada530f5267974d724ecad 315 Pfam PF03466 LysR substrate binding domain 107 311 7.5E-35 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS09340 f930e9be74ada530f5267974d724ecad 315 Gene3D G3DSA:1.10.10.10 10 97 4.2E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS09340 f930e9be74ada530f5267974d724ecad 315 TIGRFAM TIGR02424 TF_pcaQ: pca operon transcription factor PcaQ 13 313 6.2E-98 T 29-03-2018 IPR012787 Pca transcription factor PcaQ GO:0003677|GO:0019619|GO:0045893 CDC59_RS09340 f930e9be74ada530f5267974d724ecad 315 SUPERFAMILY SSF46785 15 125 1.19E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS00525 480f635aff7065e44d1dd9c79c1b1c7e 742 SUPERFAMILY SSF81660 370 510 5.89E-30 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CDC59_RS00525 480f635aff7065e44d1dd9c79c1b1c7e 742 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 359 373 6.4E-24 T 29-03-2018 CDC59_RS00525 480f635aff7065e44d1dd9c79c1b1c7e 742 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 523 533 6.4E-24 T 29-03-2018 CDC59_RS00525 480f635aff7065e44d1dd9c79c1b1c7e 742 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 201 215 6.4E-24 T 29-03-2018 CDC59_RS00525 480f635aff7065e44d1dd9c79c1b1c7e 742 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 576 595 6.4E-24 T 29-03-2018 CDC59_RS00525 480f635aff7065e44d1dd9c79c1b1c7e 742 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 599 611 6.4E-24 T 29-03-2018 CDC59_RS00525 480f635aff7065e44d1dd9c79c1b1c7e 742 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 55 740 40.645 T 29-03-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 CDC59_RS00525 480f635aff7065e44d1dd9c79c1b1c7e 742 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 118 397 2.5E-31 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CDC59_RS00525 480f635aff7065e44d1dd9c79c1b1c7e 742 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 424 664 1.0E-44 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CDC59_RS00525 480f635aff7065e44d1dd9c79c1b1c7e 742 SUPERFAMILY SSF81665 74 150 6.8E-14 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CDC59_RS00525 480f635aff7065e44d1dd9c79c1b1c7e 742 SUPERFAMILY SSF81665 679 726 6.8E-14 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CDC59_RS00525 480f635aff7065e44d1dd9c79c1b1c7e 742 SUPERFAMILY SSF81665 255 353 6.8E-14 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CDC59_RS00525 480f635aff7065e44d1dd9c79c1b1c7e 742 Pfam PF00122 E1-E2 ATPase 153 338 5.9E-32 T 29-03-2018 CDC59_RS00525 480f635aff7065e44d1dd9c79c1b1c7e 742 Pfam PF00702 haloacid dehalogenase-like hydrolase 355 590 3.3E-34 T 29-03-2018 CDC59_RS00525 480f635aff7065e44d1dd9c79c1b1c7e 742 Gene3D G3DSA:3.40.1110.10 374 501 4.8E-21 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CDC59_RS00525 480f635aff7065e44d1dd9c79c1b1c7e 742 SUPERFAMILY SSF81653 161 254 1.44E-21 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CDC59_RS00525 480f635aff7065e44d1dd9c79c1b1c7e 742 SUPERFAMILY SSF56784 441 464 3.0E-38 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS00525 480f635aff7065e44d1dd9c79c1b1c7e 742 SUPERFAMILY SSF56784 347 371 3.0E-38 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS00525 480f635aff7065e44d1dd9c79c1b1c7e 742 SUPERFAMILY SSF56784 495 618 3.0E-38 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS00525 480f635aff7065e44d1dd9c79c1b1c7e 742 Gene3D G3DSA:3.40.50.1000 502 637 1.4E-32 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS00525 480f635aff7065e44d1dd9c79c1b1c7e 742 Gene3D G3DSA:1.20.1110.10 110 373 3.6E-26 T 29-03-2018 CDC59_RS00525 480f635aff7065e44d1dd9c79c1b1c7e 742 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 361 367 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CDC59_RS00525 480f635aff7065e44d1dd9c79c1b1c7e 742 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 51 736 0.0 T 29-03-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 CDC59_RS18215 72c8718adfb3f1dc1526c3883ce60ebd 214 Pfam PF13309 HTH domain 149 208 8.6E-14 T 29-03-2018 CDC59_RS18215 72c8718adfb3f1dc1526c3883ce60ebd 214 Gene3D G3DSA:1.10.260.40 196 213 0.0014 T 29-03-2018 CDC59_RS18215 72c8718adfb3f1dc1526c3883ce60ebd 214 Pfam PF08348 YheO-like PAS domain 12 119 7.4E-32 T 29-03-2018 IPR013559 YheO-like CDC59_RS18215 72c8718adfb3f1dc1526c3883ce60ebd 214 Gene3D G3DSA:1.10.357.10 7 173 0.062 T 29-03-2018 CDC59_RS18215 72c8718adfb3f1dc1526c3883ce60ebd 214 Gene3D G3DSA:1.10.10.10 174 195 9.6E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS18215 72c8718adfb3f1dc1526c3883ce60ebd 214 ProDom PD037769 DNA-BINDING YHEO UNCHARACTERIZED BACTERIA SIMILAR HI0575 CONTAINING TRANSCRIPTION REGULATOR HELIX-TURN-HELIX 10 130 1.0E-63 T 29-03-2018 IPR013559 YheO-like CDC59_RS11395 7940468b7a58d7205f56fdaa7f43a818 436 Gene3D G3DSA:3.40.1190.10 2 294 1.0E-72 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CDC59_RS11395 7940468b7a58d7205f56fdaa7f43a818 436 Gene3D G3DSA:3.90.190.20 295 436 2.6E-28 T 29-03-2018 CDC59_RS11395 7940468b7a58d7205f56fdaa7f43a818 436 PIRSF PIRSF001563 2 435 2.8E-106 T 29-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 CDC59_RS11395 7940468b7a58d7205f56fdaa7f43a818 436 SUPERFAMILY SSF53244 293 430 3.66E-31 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CDC59_RS11395 7940468b7a58d7205f56fdaa7f43a818 436 Pfam PF02875 Mur ligase family, glutamate ligase domain 294 349 9.0E-6 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CDC59_RS11395 7940468b7a58d7205f56fdaa7f43a818 436 Pfam PF08245 Mur ligase middle domain 47 190 4.4E-10 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CDC59_RS11395 7940468b7a58d7205f56fdaa7f43a818 436 SUPERFAMILY SSF53623 6 291 3.89E-87 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CDC59_RS11395 7940468b7a58d7205f56fdaa7f43a818 436 TIGRFAM TIGR01499 folC: bifunctional protein FolC 26 428 8.2E-102 T 29-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 CDC59_RS18480 34e678ba99e5d84ca4e654bc9feb7729 155 Hamap MF_00489 UPF0178 protein YaiI [yaiI]. 1 147 30.915 T 29-03-2018 IPR003791 Protein of unknown function UPF0178 CDC59_RS18480 34e678ba99e5d84ca4e654bc9feb7729 155 Pfam PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 18 145 1.6E-47 T 29-03-2018 IPR003791 Protein of unknown function UPF0178 CDC59_RS19465 6c2ee0be7624ce382b15462e4a0a3236 608 Gene3D G3DSA:1.10.3470.10 39 318 7.0E-38 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CDC59_RS19465 6c2ee0be7624ce382b15462e4a0a3236 608 Pfam PF00005 ABC transporter 373 534 6.6E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS19465 6c2ee0be7624ce382b15462e4a0a3236 608 Pfam PF02653 Branched-chain amino acid transport system / permease component 45 313 4.0E-36 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CDC59_RS19465 6c2ee0be7624ce382b15462e4a0a3236 608 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 584 605 2.8E-9 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CDC59_RS19465 6c2ee0be7624ce382b15462e4a0a3236 608 Gene3D G3DSA:3.40.50.300 342 603 2.9E-58 T 29-03-2018 CDC59_RS19465 6c2ee0be7624ce382b15462e4a0a3236 608 SMART SM00382 381 583 1.8E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS19465 6c2ee0be7624ce382b15462e4a0a3236 608 SUPERFAMILY SSF52540 354 604 1.17E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS16615 7e8242710cc1a6ea7456dea88dca5de4 200 SUPERFAMILY SSF48452 26 159 2.22E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS16615 7e8242710cc1a6ea7456dea88dca5de4 200 Gene3D G3DSA:1.25.40.10 16 119 6.4E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS16615 7e8242710cc1a6ea7456dea88dca5de4 200 Gene3D G3DSA:1.25.40.10 120 187 3.1E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS01390 7e8242710cc1a6ea7456dea88dca5de4 200 SUPERFAMILY SSF48452 26 159 2.22E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS01390 7e8242710cc1a6ea7456dea88dca5de4 200 Gene3D G3DSA:1.25.40.10 16 119 6.4E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS01390 7e8242710cc1a6ea7456dea88dca5de4 200 Gene3D G3DSA:1.25.40.10 120 187 3.1E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS12950 b6d0f8741431a8724c7ac6559c69c42a 252 Gene3D G3DSA:3.40.50.720 1 251 8.5E-58 T 29-03-2018 CDC59_RS12950 b6d0f8741431a8724c7ac6559c69c42a 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CDC59_RS12950 b6d0f8741431a8724c7ac6559c69c42a 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.3E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS12950 b6d0f8741431a8724c7ac6559c69c42a 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 2.3E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS12950 b6d0f8741431a8724c7ac6559c69c42a 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 2.3E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS12950 b6d0f8741431a8724c7ac6559c69c42a 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 2.3E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS12950 b6d0f8741431a8724c7ac6559c69c42a 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 2.3E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS12950 b6d0f8741431a8724c7ac6559c69c42a 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 5.1E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS12950 b6d0f8741431a8724c7ac6559c69c42a 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 5.1E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS12950 b6d0f8741431a8724c7ac6559c69c42a 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 5.1E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS12950 b6d0f8741431a8724c7ac6559c69c42a 252 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 193 4.5E-4 T 29-03-2018 CDC59_RS12950 b6d0f8741431a8724c7ac6559c69c42a 252 SUPERFAMILY SSF51735 5 245 1.7E-61 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS12950 b6d0f8741431a8724c7ac6559c69c42a 252 Pfam PF00106 short chain dehydrogenase 7 196 1.0E-45 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS15945 03898e5e2ae99537494fab49aa7d9b00 842 SMART SM00387 43 208 4.6E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS15945 03898e5e2ae99537494fab49aa7d9b00 842 Pfam PF00204 DNA gyrase B 253 422 5.5E-56 T 29-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDC59_RS15945 03898e5e2ae99537494fab49aa7d9b00 842 Gene3D G3DSA:3.30.230.10 257 424 2.6E-61 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CDC59_RS15945 03898e5e2ae99537494fab49aa7d9b00 842 Gene3D G3DSA:3.30.565.10 13 256 3.1E-69 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS15945 03898e5e2ae99537494fab49aa7d9b00 842 SUPERFAMILY SSF54211 253 424 6.45E-58 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CDC59_RS15945 03898e5e2ae99537494fab49aa7d9b00 842 PRINTS PR00418 DNA topoisomerase II family signature 452 466 2.0E-66 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDC59_RS15945 03898e5e2ae99537494fab49aa7d9b00 842 PRINTS PR00418 DNA topoisomerase II family signature 774 790 2.0E-66 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDC59_RS15945 03898e5e2ae99537494fab49aa7d9b00 842 PRINTS PR00418 DNA topoisomerase II family signature 519 535 2.0E-66 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDC59_RS15945 03898e5e2ae99537494fab49aa7d9b00 842 PRINTS PR00418 DNA topoisomerase II family signature 537 554 2.0E-66 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDC59_RS15945 03898e5e2ae99537494fab49aa7d9b00 842 PRINTS PR00418 DNA topoisomerase II family signature 129 143 2.0E-66 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDC59_RS15945 03898e5e2ae99537494fab49aa7d9b00 842 PRINTS PR00418 DNA topoisomerase II family signature 82 95 2.0E-66 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDC59_RS15945 03898e5e2ae99537494fab49aa7d9b00 842 PRINTS PR00418 DNA topoisomerase II family signature 47 62 2.0E-66 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDC59_RS15945 03898e5e2ae99537494fab49aa7d9b00 842 PRINTS PR00418 DNA topoisomerase II family signature 300 313 2.0E-66 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDC59_RS15945 03898e5e2ae99537494fab49aa7d9b00 842 PRINTS PR00418 DNA topoisomerase II family signature 557 569 2.0E-66 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDC59_RS15945 03898e5e2ae99537494fab49aa7d9b00 842 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 14 842 99.529 T 29-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CDC59_RS15945 03898e5e2ae99537494fab49aa7d9b00 842 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 771 831 6.3E-28 T 29-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 CDC59_RS15945 03898e5e2ae99537494fab49aa7d9b00 842 PRINTS PR01159 DNA gyrase subunit B signature 406 426 1.6E-72 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CDC59_RS15945 03898e5e2ae99537494fab49aa7d9b00 842 PRINTS PR01159 DNA gyrase subunit B signature 795 807 1.6E-72 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CDC59_RS15945 03898e5e2ae99537494fab49aa7d9b00 842 PRINTS PR01159 DNA gyrase subunit B signature 228 241 1.6E-72 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CDC59_RS15945 03898e5e2ae99537494fab49aa7d9b00 842 PRINTS PR01159 DNA gyrase subunit B signature 344 360 1.6E-72 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CDC59_RS15945 03898e5e2ae99537494fab49aa7d9b00 842 PRINTS PR01159 DNA gyrase subunit B signature 502 511 1.6E-72 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CDC59_RS15945 03898e5e2ae99537494fab49aa7d9b00 842 PRINTS PR01159 DNA gyrase subunit B signature 811 827 1.6E-72 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CDC59_RS15945 03898e5e2ae99537494fab49aa7d9b00 842 PRINTS PR01159 DNA gyrase subunit B signature 213 228 1.6E-72 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CDC59_RS15945 03898e5e2ae99537494fab49aa7d9b00 842 PRINTS PR01159 DNA gyrase subunit B signature 252 274 1.6E-72 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CDC59_RS15945 03898e5e2ae99537494fab49aa7d9b00 842 PRINTS PR01159 DNA gyrase subunit B signature 392 406 1.6E-72 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CDC59_RS15945 03898e5e2ae99537494fab49aa7d9b00 842 PRINTS PR01159 DNA gyrase subunit B signature 17 27 1.6E-72 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CDC59_RS15945 03898e5e2ae99537494fab49aa7d9b00 842 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 44 207 2.4E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS15945 03898e5e2ae99537494fab49aa7d9b00 842 ProSitePatterns PS00177 DNA topoisomerase II signature. 454 462 - T 29-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDC59_RS15945 03898e5e2ae99537494fab49aa7d9b00 842 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 17 842 7.3E-290 T 29-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CDC59_RS15945 03898e5e2ae99537494fab49aa7d9b00 842 SUPERFAMILY SSF55874 17 248 4.32E-64 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS15945 03898e5e2ae99537494fab49aa7d9b00 842 SMART SM00433 47 835 1.0E-245 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDC59_RS15945 03898e5e2ae99537494fab49aa7d9b00 842 Gene3D G3DSA:3.40.50.670 432 839 1.1E-106 T 29-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDC59_RS15945 03898e5e2ae99537494fab49aa7d9b00 842 Pfam PF01751 Toprim domain 451 563 1.6E-18 T 29-03-2018 IPR006171 TOPRIM domain CDC59_RS15945 03898e5e2ae99537494fab49aa7d9b00 842 SUPERFAMILY SSF56719 768 832 5.23E-87 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CDC59_RS15945 03898e5e2ae99537494fab49aa7d9b00 842 SUPERFAMILY SSF56719 426 592 5.23E-87 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CDC59_RS12475 09265b432c4235cbd436e6f6b87d1ca0 313 Gene3D G3DSA:3.40.190.10 90 180 1.6E-22 T 29-03-2018 CDC59_RS12475 09265b432c4235cbd436e6f6b87d1ca0 313 SUPERFAMILY SSF46785 12 113 4.3E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS12475 09265b432c4235cbd436e6f6b87d1ca0 313 Pfam PF03466 LysR substrate binding domain 89 292 3.0E-39 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS12475 09265b432c4235cbd436e6f6b87d1ca0 313 Gene3D G3DSA:1.10.10.10 1 83 1.4E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS12475 09265b432c4235cbd436e6f6b87d1ca0 313 SUPERFAMILY SSF53850 91 298 4.53E-41 T 29-03-2018 CDC59_RS12475 09265b432c4235cbd436e6f6b87d1ca0 313 Gene3D G3DSA:3.40.190.10 181 267 1.9E-20 T 29-03-2018 CDC59_RS12475 09265b432c4235cbd436e6f6b87d1ca0 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 64 3.5E-14 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS12475 09265b432c4235cbd436e6f6b87d1ca0 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.3E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS12475 09265b432c4235cbd436e6f6b87d1ca0 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.3E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS12475 09265b432c4235cbd436e6f6b87d1ca0 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.3E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS10030 d55f5b21cbd116db1a8b16cd91e58f4c 329 SUPERFAMILY SSF53822 49 253 6.85E-18 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CDC59_RS10030 d55f5b21cbd116db1a8b16cd91e58f4c 329 Pfam PF04392 ABC transporter substrate binding protein 37 327 2.4E-106 T 29-03-2018 IPR007487 ABC transporter, substrate-binding protein CDC59_RS10030 d55f5b21cbd116db1a8b16cd91e58f4c 329 Gene3D G3DSA:3.40.50.2300 156 292 9.2E-19 T 29-03-2018 CDC59_RS10030 d55f5b21cbd116db1a8b16cd91e58f4c 329 Gene3D G3DSA:3.40.50.2300 33 155 5.3E-23 T 29-03-2018 CDC59_RS05520 50649c35ed1da9f1878f7901b49386be 331 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 241 1.6E-45 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CDC59_RS05520 50649c35ed1da9f1878f7901b49386be 331 Hamap MF_01601 ADP-L-glycero-D-manno-heptose-6-epimerase [hldD]. 2 329 50.711 T 29-03-2018 IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase GO:0005975|GO:0008712|GO:0050661 KEGG: 00540+5.1.3.20 CDC59_RS05520 50649c35ed1da9f1878f7901b49386be 331 Gene3D G3DSA:3.40.50.720 1 164 3.6E-18 T 29-03-2018 CDC59_RS05520 50649c35ed1da9f1878f7901b49386be 331 TIGRFAM TIGR02197 heptose_epim: ADP-glyceromanno-heptose 6-epimerase 3 328 7.5E-139 T 29-03-2018 IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase GO:0005975|GO:0008712|GO:0050661 KEGG: 00540+5.1.3.20 CDC59_RS05520 50649c35ed1da9f1878f7901b49386be 331 Gene3D G3DSA:3.90.25.10 165 331 5.2E-25 T 29-03-2018 CDC59_RS05520 50649c35ed1da9f1878f7901b49386be 331 SUPERFAMILY SSF51735 1 328 1.26E-58 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS23100 cddf3ca966b57adfbcdb364d9ca9945d 163 Pfam PF01584 CheW-like domain 16 150 1.4E-37 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CDC59_RS23100 cddf3ca966b57adfbcdb364d9ca9945d 163 SMART SM00260 12 149 6.8E-41 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CDC59_RS23100 cddf3ca966b57adfbcdb364d9ca9945d 163 SUPERFAMILY SSF50341 15 149 3.01E-39 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CDC59_RS23100 cddf3ca966b57adfbcdb364d9ca9945d 163 Gene3D G3DSA:2.40.50.180 33 97 7.3E-20 T 29-03-2018 CDC59_RS23100 cddf3ca966b57adfbcdb364d9ca9945d 163 Gene3D G3DSA:2.30.30.40 98 143 5.0E-18 T 29-03-2018 CDC59_RS23105 03ab311eec8582066ec743cce16726de 727 SUPERFAMILY SSF47226 5 126 7.46E-31 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CDC59_RS23105 03ab311eec8582066ec743cce16726de 727 Pfam PF01627 Hpt domain 9 105 1.4E-18 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CDC59_RS23105 03ab311eec8582066ec743cce16726de 727 Gene3D G3DSA:2.30.30.40 636 688 9.4E-21 T 29-03-2018 CDC59_RS23105 03ab311eec8582066ec743cce16726de 727 Gene3D G3DSA:2.30.30.40 561 593 0.0027 T 29-03-2018 CDC59_RS23105 03ab311eec8582066ec743cce16726de 727 SUPERFAMILY SSF55874 374 554 7.99E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS23105 03ab311eec8582066ec743cce16726de 727 SMART SM01231 308 371 7.1E-22 T 29-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 CDC59_RS23105 03ab311eec8582066ec743cce16726de 727 SUPERFAMILY SSF47384 309 372 1.06E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS23105 03ab311eec8582066ec743cce16726de 727 SMART SM00387 416 556 2.6E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS23105 03ab311eec8582066ec743cce16726de 727 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 419 555 1.9E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS23105 03ab311eec8582066ec743cce16726de 727 Gene3D G3DSA:1.20.120.160 1 169 3.5E-29 T 29-03-2018 CDC59_RS23105 03ab311eec8582066ec743cce16726de 727 Gene3D G3DSA:3.30.70.400 174 239 1.8E-21 T 29-03-2018 IPR015162 CheY binding CDC59_RS23105 03ab311eec8582066ec743cce16726de 727 PRINTS PR00344 Bacterial sensor protein C-terminal signature 516 534 2.3E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS23105 03ab311eec8582066ec743cce16726de 727 PRINTS PR00344 Bacterial sensor protein C-terminal signature 500 510 2.3E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS23105 03ab311eec8582066ec743cce16726de 727 PRINTS PR00344 Bacterial sensor protein C-terminal signature 461 475 2.3E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS23105 03ab311eec8582066ec743cce16726de 727 PRINTS PR00344 Bacterial sensor protein C-terminal signature 540 553 2.3E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS23105 03ab311eec8582066ec743cce16726de 727 Pfam PF01584 CheW-like domain 561 690 2.7E-25 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CDC59_RS23105 03ab311eec8582066ec743cce16726de 727 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 309 371 4.9E-17 T 29-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 CDC59_RS23105 03ab311eec8582066ec743cce16726de 727 SMART SM00260 548 688 2.2E-37 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CDC59_RS23105 03ab311eec8582066ec743cce16726de 727 SUPERFAMILY SSF55052 175 239 4.45E-19 T 29-03-2018 IPR015162 CheY binding CDC59_RS23105 03ab311eec8582066ec743cce16726de 727 SUPERFAMILY SSF50341 555 688 5.36E-29 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CDC59_RS23105 03ab311eec8582066ec743cce16726de 727 Gene3D G3DSA:1.10.287.560 308 372 1.6E-18 T 29-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 CDC59_RS23105 03ab311eec8582066ec743cce16726de 727 Gene3D G3DSA:2.40.50.180 594 635 1.3E-6 T 29-03-2018 CDC59_RS23105 03ab311eec8582066ec743cce16726de 727 Gene3D G3DSA:3.30.565.10 374 560 1.5E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS23105 03ab311eec8582066ec743cce16726de 727 SMART SM00073 5 102 6.6E-30 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CDC59_RS23105 03ab311eec8582066ec743cce16726de 727 Pfam PF09078 CheY binding 177 238 2.5E-22 T 29-03-2018 IPR015162 CheY binding CDC59_RS09395 41ca04a47fda944a98617f97ae200ca4 212 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 3 212 33.791 T 29-03-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 CDC59_RS09395 41ca04a47fda944a98617f97ae200ca4 212 TIGRFAM TIGR04508 queE_Cx14CxxC: 7-carboxy-7-deazaguanine synthase 3 212 2.2E-107 T 29-03-2018 IPR030977 7-carboxy-7-deazaguanine synthase, Cx14CxxC-type GO:0008616|GO:0046872 KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 CDC59_RS09395 41ca04a47fda944a98617f97ae200ca4 212 Gene3D G3DSA:3.20.20.70 25 206 2.5E-10 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS09395 41ca04a47fda944a98617f97ae200ca4 212 SUPERFAMILY SSF102114 46 135 1.18E-5 T 29-03-2018 CDC59_RS09395 41ca04a47fda944a98617f97ae200ca4 212 PIRSF PIRSF000370 1 212 1.3E-34 T 29-03-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 CDC59_RS02960 cbc03f9edde6ffe4c050b1931edcb988 262 SUPERFAMILY SSF52096 1 261 2.93E-79 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CDC59_RS02960 cbc03f9edde6ffe4c050b1931edcb988 262 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 102 122 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CDC59_RS02960 cbc03f9edde6ffe4c050b1931edcb988 262 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 261 1.5E-63 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CDC59_RS02960 cbc03f9edde6ffe4c050b1931edcb988 262 Gene3D G3DSA:3.90.226.10 5 219 5.9E-63 T 29-03-2018 CDC59_RS02960 cbc03f9edde6ffe4c050b1931edcb988 262 TIGRFAM TIGR02280 PaaB1: phenylacetate degradation probable enoyl-CoA hydratase PaaB 6 262 1.7E-141 T 29-03-2018 IPR011968 Phenylacetate degradation probable enoyl-CoA hydratase PaaB GO:0010124 KEGG: 00360+5.3.3.18 CDC59_RS02960 cbc03f9edde6ffe4c050b1931edcb988 262 Gene3D G3DSA:1.10.12.10 220 261 9.4E-16 T 29-03-2018 IPR014748 Crontonase, C-terminal CDC59_RS21905 9e585bd95fcff16ff3d78ce572835cf4 187 Pfam PF09411 Lipid A 3-O-deacylase (PagL) 49 186 8.1E-38 T 29-03-2018 IPR018550 Lipid A 3-O-deacylase-related CDC59_RS21905 9e585bd95fcff16ff3d78ce572835cf4 187 Gene3D G3DSA:2.40.160.20 33 187 6.4E-31 T 29-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CDC59_RS21905 9e585bd95fcff16ff3d78ce572835cf4 187 SUPERFAMILY SSF56925 45 187 2.3E-12 T 29-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CDC59_RS21905 9e585bd95fcff16ff3d78ce572835cf4 187 PIRSF PIRSF029681 2 187 5.5E-61 T 29-03-2018 IPR018550 Lipid A 3-O-deacylase-related CDC59_RS03645 ad1e722dc9183444b987f7176412b522 379 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 140 369 6.2E-74 T 29-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CDC59_RS03645 ad1e722dc9183444b987f7176412b522 379 SUPERFAMILY SSF51735 136 319 2.94E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS03645 ad1e722dc9183444b987f7176412b522 379 Gene3D G3DSA:3.40.50.720 1 192 1.6E-44 T 29-03-2018 CDC59_RS03645 ad1e722dc9183444b987f7176412b522 379 SUPERFAMILY SSF52283 1 167 3.32E-51 T 29-03-2018 CDC59_RS03645 ad1e722dc9183444b987f7176412b522 379 SMART SM01003 4 136 4.8E-67 T 29-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CDC59_RS03645 ad1e722dc9183444b987f7176412b522 379 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 136 3.4E-42 T 29-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CDC59_RS03645 ad1e722dc9183444b987f7176412b522 379 SMART SM01002 145 314 9.7E-85 T 29-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CDC59_RS03645 ad1e722dc9183444b987f7176412b522 379 Gene3D G3DSA:3.40.50.720 193 378 7.3E-45 T 29-03-2018 CDC59_RS20835 a8351c8e16f5c396cb54f7323706a381 423 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 11 414 2.1E-127 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CDC59_RS20835 a8351c8e16f5c396cb54f7323706a381 423 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 11 194 3.1E-61 T 29-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CDC59_RS20835 a8351c8e16f5c396cb54f7323706a381 423 SMART SM00984 322 418 2.3E-27 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CDC59_RS20835 a8351c8e16f5c396cb54f7323706a381 423 SUPERFAMILY SSF51735 10 204 7.68E-48 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS20835 a8351c8e16f5c396cb54f7323706a381 423 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 212 299 1.7E-28 T 29-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CDC59_RS20835 a8351c8e16f5c396cb54f7323706a381 423 SUPERFAMILY SSF48179 212 305 9.18E-30 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CDC59_RS20835 a8351c8e16f5c396cb54f7323706a381 423 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 322 416 2.4E-20 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CDC59_RS20835 a8351c8e16f5c396cb54f7323706a381 423 PIRSF PIRSF500136 1 423 1.3E-159 T 29-03-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 CDC59_RS20835 a8351c8e16f5c396cb54f7323706a381 423 Gene3D G3DSA:3.40.50.720 8 211 1.7E-47 T 29-03-2018 CDC59_RS20835 a8351c8e16f5c396cb54f7323706a381 423 Gene3D G3DSA:1.20.5.170 212 235 7.4E-16 T 29-03-2018 CDC59_RS20835 a8351c8e16f5c396cb54f7323706a381 423 Gene3D G3DSA:3.40.50.720 236 423 1.7E-56 T 29-03-2018 CDC59_RS20835 a8351c8e16f5c396cb54f7323706a381 423 SUPERFAMILY SSF52413 311 421 4.58E-25 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CDC59_RS20835 a8351c8e16f5c396cb54f7323706a381 423 PIRSF PIRSF000124 10 423 4.3E-83 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CDC59_RS04035 9d7037dce2b967e547c9ddf4fe438a0f 352 Gene3D G3DSA:3.30.450.40 197 352 6.3E-39 T 29-03-2018 IPR029016 GAF domain-like CDC59_RS04035 9d7037dce2b967e547c9ddf4fe438a0f 352 Gene3D G3DSA:1.10.10.10 89 127 0.32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS04035 9d7037dce2b967e547c9ddf4fe438a0f 352 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 1 342 25.531 T 29-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CDC59_RS04035 9d7037dce2b967e547c9ddf4fe438a0f 352 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 2 347 2.5E-89 T 29-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CDC59_RS04035 9d7037dce2b967e547c9ddf4fe438a0f 352 SUPERFAMILY SSF55781 70 83 2.55E-58 T 29-03-2018 IPR029016 GAF domain-like CDC59_RS04035 9d7037dce2b967e547c9ddf4fe438a0f 352 SUPERFAMILY SSF55781 115 351 2.55E-58 T 29-03-2018 IPR029016 GAF domain-like CDC59_RS04035 9d7037dce2b967e547c9ddf4fe438a0f 352 Gene3D G3DSA:1.10.10.10 1 83 8.5E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS04035 9d7037dce2b967e547c9ddf4fe438a0f 352 SUPERFAMILY SSF46785 1 80 7.89E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS04035 9d7037dce2b967e547c9ddf4fe438a0f 352 PIRSF PIRSF005485 1 352 1.3E-102 T 29-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CDC59_RS04035 9d7037dce2b967e547c9ddf4fe438a0f 352 Pfam PF01628 HrcA protein C terminal domain 118 335 9.1E-55 T 29-03-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 CDC59_RS10185 82f2f15b36292e7707d035658809f203 449 Pfam PF05697 Bacterial trigger factor protein (TF) 1 143 1.0E-33 T 29-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CDC59_RS10185 82f2f15b36292e7707d035658809f203 449 SUPERFAMILY SSF102735 1 131 4.58E-30 T 29-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CDC59_RS10185 82f2f15b36292e7707d035658809f203 449 TIGRFAM TIGR00115 tig: trigger factor 12 425 5.4E-125 T 29-03-2018 IPR005215 Trigger factor GO:0015031 CDC59_RS10185 82f2f15b36292e7707d035658809f203 449 Gene3D G3DSA:1.10.3120.10 238 403 1.4E-44 T 29-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 CDC59_RS10185 82f2f15b36292e7707d035658809f203 449 Hamap MF_00303 Trigger factor [tig]. 1 432 20.644 T 29-03-2018 IPR005215 Trigger factor GO:0015031 CDC59_RS10185 82f2f15b36292e7707d035658809f203 449 PIRSF PIRSF003095 1 448 2.1E-129 T 29-03-2018 IPR005215 Trigger factor GO:0015031 CDC59_RS10185 82f2f15b36292e7707d035658809f203 449 SUPERFAMILY SSF109998 259 442 1.18E-49 T 29-03-2018 IPR027304 Trigger factor/SurA domain CDC59_RS10185 82f2f15b36292e7707d035658809f203 449 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 273 426 5.9E-40 T 29-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 CDC59_RS10185 82f2f15b36292e7707d035658809f203 449 Gene3D G3DSA:3.10.50.40 168 237 6.2E-12 T 29-03-2018 CDC59_RS10185 82f2f15b36292e7707d035658809f203 449 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 168 248 4.6E-13 T 29-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain CDC59_RS10185 82f2f15b36292e7707d035658809f203 449 SUPERFAMILY SSF54534 98 252 3.73E-28 T 29-03-2018 CDC59_RS10185 82f2f15b36292e7707d035658809f203 449 Gene3D G3DSA:3.30.70.1050 1 119 2.0E-25 T 29-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CDC59_RS09385 becade67e0c3dd81489384a3f1e210ed 445 Pfam PF07804 HipA-like C-terminal domain 155 402 3.3E-49 T 29-03-2018 IPR012893 HipA-like, C-terminal CDC59_RS09385 becade67e0c3dd81489384a3f1e210ed 445 TIGRFAM TIGR03071 couple_hipA: HipA N-terminal domain 5 107 5.4E-32 T 29-03-2018 IPR017508 HipA, N-terminal subdomain 1 CDC59_RS09385 becade67e0c3dd81489384a3f1e210ed 445 Pfam PF13657 HipA N-terminal domain 6 107 5.0E-20 T 29-03-2018 IPR017508 HipA, N-terminal subdomain 1 CDC59_RS19835 c890693791f919acab3b87c217496fb6 1081 SUPERFAMILY SSF89550 20 88 6.08E-8 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CDC59_RS19835 c890693791f919acab3b87c217496fb6 1081 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 21 1026 1.9E-152 T 29-03-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDC59_RS19835 c890693791f919acab3b87c217496fb6 1081 SMART SM00481 21 88 9.7E-15 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CDC59_RS19835 c890693791f919acab3b87c217496fb6 1081 Hamap MF_01902 Error-prone DNA polymerase [dnaE2]. 20 1081 13.717 T 29-03-2018 IPR023073 DNA polymerase, error-prone GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDC59_RS19835 c890693791f919acab3b87c217496fb6 1081 Pfam PF02811 PHP domain 22 147 4.4E-15 T 29-03-2018 IPR004013 PHP domain GO:0003824 CDC59_RS19835 c890693791f919acab3b87c217496fb6 1081 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 307 741 1.3E-143 T 29-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDC59_RS19835 c890693791f919acab3b87c217496fb6 1081 Pfam PF14579 Helix-hairpin-helix motif 818 910 4.1E-22 T 29-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDC59_RS19835 c890693791f919acab3b87c217496fb6 1081 Gene3D G3DSA:2.40.50.140 958 1069 6.5E-8 T 29-03-2018 CDC59_RS19835 c890693791f919acab3b87c217496fb6 1081 Gene3D G3DSA:3.20.20.140 19 265 8.3E-35 T 29-03-2018 CDC59_RS07475 a1e0cda359e16ead2b6392feaaed07ff 803 Pfam PF01055 Glycosyl hydrolases family 31 243 687 1.9E-115 T 29-03-2018 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 CDC59_RS07475 a1e0cda359e16ead2b6392feaaed07ff 803 Pfam PF13802 Galactose mutarotase-like 149 218 3.6E-21 T 29-03-2018 IPR025887 Glycoside hydrolase family 31, N-terminal domain CDC59_RS07475 a1e0cda359e16ead2b6392feaaed07ff 803 Gene3D G3DSA:2.60.40.1760 9 249 5.0E-42 T 29-03-2018 CDC59_RS07475 a1e0cda359e16ead2b6392feaaed07ff 803 SUPERFAMILY SSF51011 602 682 6.83E-19 T 29-03-2018 CDC59_RS07475 a1e0cda359e16ead2b6392feaaed07ff 803 SUPERFAMILY SSF51445 253 597 2.46E-66 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CDC59_RS07475 a1e0cda359e16ead2b6392feaaed07ff 803 Gene3D G3DSA:2.60.40.1180 622 683 5.5E-24 T 29-03-2018 CDC59_RS07475 a1e0cda359e16ead2b6392feaaed07ff 803 Gene3D G3DSA:3.20.20.80 250 621 6.8E-106 T 29-03-2018 CDC59_RS07475 a1e0cda359e16ead2b6392feaaed07ff 803 SUPERFAMILY SSF74650 10 249 1.0E-46 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CDC59_RS10960 8da4f5e50a74c9ca3b80208387a97864 158 Gene3D G3DSA:1.10.287.180 3 76 1.3E-31 T 29-03-2018 CDC59_RS10960 8da4f5e50a74c9ca3b80208387a97864 158 PIRSF PIRSF006092 1 158 4.9E-51 T 29-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 CDC59_RS10960 8da4f5e50a74c9ca3b80208387a97864 158 SUPERFAMILY SSF54534 83 157 7.19E-23 T 29-03-2018 CDC59_RS10960 8da4f5e50a74c9ca3b80208387a97864 158 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 5 156 1.7E-55 T 29-03-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 CDC59_RS10960 8da4f5e50a74c9ca3b80208387a97864 158 Hamap MF_00105 Transcription elongation factor GreA [greA]. 2 156 33.473 T 29-03-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 CDC59_RS10960 8da4f5e50a74c9ca3b80208387a97864 158 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 121 137 - T 29-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 CDC59_RS10960 8da4f5e50a74c9ca3b80208387a97864 158 SUPERFAMILY SSF46557 3 77 3.79E-27 T 29-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CDC59_RS10960 8da4f5e50a74c9ca3b80208387a97864 158 Gene3D G3DSA:3.10.50.30 78 158 2.2E-27 T 29-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CDC59_RS10960 8da4f5e50a74c9ca3b80208387a97864 158 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 17 48 - T 29-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 CDC59_RS10960 8da4f5e50a74c9ca3b80208387a97864 158 Pfam PF03449 Transcription elongation factor, N-terminal 4 74 9.1E-31 T 29-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CDC59_RS10960 8da4f5e50a74c9ca3b80208387a97864 158 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 83 157 2.3E-27 T 29-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CDC59_RS13420 8292810dc29db2cedd1656b5c5dbfc3a 173 SUPERFAMILY SSF54523 16 118 1.57E-19 T 29-03-2018 CDC59_RS13420 8292810dc29db2cedd1656b5c5dbfc3a 173 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 13 36 8.2E-11 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS13420 8292810dc29db2cedd1656b5c5dbfc3a 173 Gene3D G3DSA:3.30.700.10 16 173 3.8E-27 T 29-03-2018 CDC59_RS13420 8292810dc29db2cedd1656b5c5dbfc3a 173 Pfam PF07963 Prokaryotic N-terminal methylation motif 10 35 2.4E-11 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS13420 8292810dc29db2cedd1656b5c5dbfc3a 173 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 14 34 - T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS13420 8292810dc29db2cedd1656b5c5dbfc3a 173 Pfam PF00114 Pilin (bacterial filament) 45 173 7.9E-11 T 29-03-2018 IPR001082 Fimbrial protein pilin GO:0007155|GO:0009289 CDC59_RS18635 b9d3af7d4cf46422a35112516b64fba1 454 Gene3D G3DSA:2.30.40.10 17 102 1.0E-15 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CDC59_RS18635 b9d3af7d4cf46422a35112516b64fba1 454 SUPERFAMILY SSF51338 388 436 1.2E-16 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CDC59_RS18635 b9d3af7d4cf46422a35112516b64fba1 454 SUPERFAMILY SSF51338 20 87 1.2E-16 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CDC59_RS18635 b9d3af7d4cf46422a35112516b64fba1 454 Pfam PF01979 Amidohydrolase family 84 435 8.8E-32 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CDC59_RS18635 b9d3af7d4cf46422a35112516b64fba1 454 Gene3D G3DSA:3.20.20.140 103 404 2.4E-44 T 29-03-2018 CDC59_RS18635 b9d3af7d4cf46422a35112516b64fba1 454 SUPERFAMILY SSF51556 86 389 9.79E-55 T 29-03-2018 IPR032466 Metal-dependent hydrolase CDC59_RS03045 df539b71f82aade4da79a6171643700a 844 Pfam PF00381 PTS HPr component phosphorylation site 162 238 7.5E-22 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CDC59_RS03045 df539b71f82aade4da79a6171643700a 844 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 8 143 7.8E-31 T 29-03-2018 IPR002178 PTS EIIA type-2 domain CDC59_RS03045 df539b71f82aade4da79a6171643700a 844 Gene3D G3DSA:3.30.1340.10 160 243 5.4E-23 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CDC59_RS03045 df539b71f82aade4da79a6171643700a 844 Gene3D G3DSA:3.50.30.10 403 523 2.8E-26 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CDC59_RS03045 df539b71f82aade4da79a6171643700a 844 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 764 776 1.1E-20 T 29-03-2018 CDC59_RS03045 df539b71f82aade4da79a6171643700a 844 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 711 726 1.1E-20 T 29-03-2018 CDC59_RS03045 df539b71f82aade4da79a6171643700a 844 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 562 581 1.1E-20 T 29-03-2018 CDC59_RS03045 df539b71f82aade4da79a6171643700a 844 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 728 743 1.1E-20 T 29-03-2018 CDC59_RS03045 df539b71f82aade4da79a6171643700a 844 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 49 65 - T 29-03-2018 IPR002178 PTS EIIA type-2 domain CDC59_RS03045 df539b71f82aade4da79a6171643700a 844 SUPERFAMILY SSF52009 394 514 2.35E-30 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CDC59_RS03045 df539b71f82aade4da79a6171643700a 844 PRINTS PR00107 Phosphocarrier protein signature 210 227 2.5E-13 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CDC59_RS03045 df539b71f82aade4da79a6171643700a 844 PRINTS PR00107 Phosphocarrier protein signature 195 210 2.5E-13 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CDC59_RS03045 df539b71f82aade4da79a6171643700a 844 PRINTS PR00107 Phosphocarrier protein signature 170 186 2.5E-13 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CDC59_RS03045 df539b71f82aade4da79a6171643700a 844 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 170 177 - T 29-03-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site CDC59_RS03045 df539b71f82aade4da79a6171643700a 844 Gene3D G3DSA:3.20.20.60 524 835 7.6E-97 T 29-03-2018 CDC59_RS03045 df539b71f82aade4da79a6171643700a 844 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 453 464 - T 29-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 CDC59_RS03045 df539b71f82aade4da79a6171643700a 844 SUPERFAMILY SSF55594 162 240 1.83E-20 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CDC59_RS03045 df539b71f82aade4da79a6171643700a 844 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 163 238 2.3E-16 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CDC59_RS03045 df539b71f82aade4da79a6171643700a 844 Pfam PF05524 PEP-utilising enzyme, N-terminal 276 394 3.3E-17 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CDC59_RS03045 df539b71f82aade4da79a6171643700a 844 Gene3D G3DSA:3.40.930.10 2 145 2.2E-29 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CDC59_RS03045 df539b71f82aade4da79a6171643700a 844 Pfam PF00391 PEP-utilising enzyme, mobile domain 424 494 1.0E-21 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CDC59_RS03045 df539b71f82aade4da79a6171643700a 844 Gene3D G3DSA:1.10.274.10 305 402 9.6E-22 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CDC59_RS03045 df539b71f82aade4da79a6171643700a 844 SUPERFAMILY SSF55804 5 143 1.07E-34 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CDC59_RS03045 df539b71f82aade4da79a6171643700a 844 SUPERFAMILY SSF51621 522 813 1.81E-103 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CDC59_RS03045 df539b71f82aade4da79a6171643700a 844 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 711 729 - T 29-03-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 CDC59_RS03045 df539b71f82aade4da79a6171643700a 844 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 274 828 4.3E-139 T 29-03-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 CDC59_RS03045 df539b71f82aade4da79a6171643700a 844 SUPERFAMILY SSF47831 310 409 3.4E-21 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CDC59_RS03045 df539b71f82aade4da79a6171643700a 844 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 521 805 2.4E-105 T 29-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 CDC59_RS04435 2cb0955cdf09fb6047b261041b6c8cb5 144 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 19 140 1.9E-25 T 29-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CDC59_RS04435 2cb0955cdf09fb6047b261041b6c8cb5 144 Gene3D G3DSA:3.30.420.140 14 144 2.6E-34 T 29-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 CDC59_RS04435 2cb0955cdf09fb6047b261041b6c8cb5 144 SMART SM00732 16 116 1.2E-27 T 29-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 CDC59_RS04435 2cb0955cdf09fb6047b261041b6c8cb5 144 Pfam PF03652 Holliday junction resolvase 17 141 1.5E-33 T 29-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CDC59_RS04435 2cb0955cdf09fb6047b261041b6c8cb5 144 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 16 143 21.541 T 29-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CDC59_RS04435 2cb0955cdf09fb6047b261041b6c8cb5 144 SUPERFAMILY SSF53098 16 141 1.03E-33 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDC59_RS00130 f30baf0a050f0c06e086e974333c07a4 487 Pfam PF07730 Histidine kinase 249 327 9.0E-22 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CDC59_RS00130 f30baf0a050f0c06e086e974333c07a4 487 SUPERFAMILY SSF55874 350 462 2.75E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS00130 f30baf0a050f0c06e086e974333c07a4 487 PIRSF PIRSF037314 1 480 4.9E-191 T 29-03-2018 IPR017171 Signal transduction histidine kinase, MctS CDC59_RS00130 f30baf0a050f0c06e086e974333c07a4 487 Gene3D G3DSA:3.30.565.10 288 463 1.3E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS00130 f30baf0a050f0c06e086e974333c07a4 487 SMART SM01049 42 132 2.7E-29 T 29-03-2018 IPR033480 Single Cache domain 2 CDC59_RS00130 f30baf0a050f0c06e086e974333c07a4 487 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 375 462 1.8E-5 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS00130 f30baf0a050f0c06e086e974333c07a4 487 SMART SM00387 370 466 3.1E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS00130 f30baf0a050f0c06e086e974333c07a4 487 Gene3D G3DSA:3.30.450.20 25 205 2.7E-48 T 29-03-2018 CDC59_RS00130 f30baf0a050f0c06e086e974333c07a4 487 Pfam PF17200 Single Cache domain 2 47 191 1.4E-38 T 29-03-2018 IPR033480 Single Cache domain 2 CDC59_RS20810 6e6262ace0d98867c72b9c87beedfd0c 713 SUPERFAMILY SSF50129 337 360 8.09E-16 T 29-03-2018 IPR011032 GroES-like CDC59_RS20810 6e6262ace0d98867c72b9c87beedfd0c 713 SUPERFAMILY SSF50129 87 145 8.09E-16 T 29-03-2018 IPR011032 GroES-like CDC59_RS20810 6e6262ace0d98867c72b9c87beedfd0c 713 Gene3D G3DSA:3.30.360.10 526 713 4.2E-24 T 29-03-2018 CDC59_RS20810 6e6262ace0d98867c72b9c87beedfd0c 713 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 395 506 4.3E-17 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CDC59_RS20810 6e6262ace0d98867c72b9c87beedfd0c 713 Gene3D G3DSA:3.90.180.10 49 176 6.2E-25 T 29-03-2018 CDC59_RS20810 6e6262ace0d98867c72b9c87beedfd0c 713 Gene3D G3DSA:3.40.50.720 177 286 3.8E-20 T 29-03-2018 CDC59_RS20810 6e6262ace0d98867c72b9c87beedfd0c 713 Pfam PF00107 Zinc-binding dehydrogenase 178 300 3.8E-19 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CDC59_RS20810 6e6262ace0d98867c72b9c87beedfd0c 713 Gene3D G3DSA:3.40.50.720 390 525 1.7E-25 T 29-03-2018 CDC59_RS20810 6e6262ace0d98867c72b9c87beedfd0c 713 SUPERFAMILY SSF51735 143 336 8.23E-28 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS20810 6e6262ace0d98867c72b9c87beedfd0c 713 SUPERFAMILY SSF51735 396 563 3.57E-33 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS20810 6e6262ace0d98867c72b9c87beedfd0c 713 Gene3D G3DSA:3.90.180.10 309 369 1.6E-6 T 29-03-2018 CDC59_RS20810 6e6262ace0d98867c72b9c87beedfd0c 713 SUPERFAMILY SSF55347 523 655 6.8E-17 T 29-03-2018 CDC59_RS20810 6e6262ace0d98867c72b9c87beedfd0c 713 SMART SM00829 78 361 1.5E-5 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CDC59_RS19505 2e8255eed0acf496db0f64dd4696e1f8 290 Gene3D G3DSA:3.30.470.10 1 133 6.7E-31 T 29-03-2018 CDC59_RS19505 2e8255eed0acf496db0f64dd4696e1f8 290 Pfam PF01063 Amino-transferase class IV 31 254 4.2E-41 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CDC59_RS19505 2e8255eed0acf496db0f64dd4696e1f8 290 Gene3D G3DSA:3.20.10.10 134 282 3.2E-40 T 29-03-2018 CDC59_RS19505 2e8255eed0acf496db0f64dd4696e1f8 290 SUPERFAMILY SSF56752 4 277 1.57E-77 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CDC59_RS12195 a9356ef1737bf87e4a1e2fcf5202869c 188 SUPERFAMILY SSF51283 3 187 2.22E-53 T 29-03-2018 IPR029054 dUTPase-like CDC59_RS12195 a9356ef1737bf87e4a1e2fcf5202869c 188 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 4 187 7.7E-51 T 29-03-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 CDC59_RS12195 a9356ef1737bf87e4a1e2fcf5202869c 188 Hamap MF_00146 dCTP deaminase [dcd]. 1 188 28.837 T 29-03-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 CDC59_RS12195 a9356ef1737bf87e4a1e2fcf5202869c 188 Gene3D G3DSA:2.70.40.10 1 161 1.1E-58 T 29-03-2018 CDC59_RS12195 a9356ef1737bf87e4a1e2fcf5202869c 188 Pfam PF00692 dUTPase 82 184 3.5E-6 T 29-03-2018 IPR029054 dUTPase-like CDC59_RS22745 4752c7d5f4a5d7d9963f20039ca49c3e 246 Gene3D G3DSA:1.10.10.10 128 232 1.4E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS22745 4752c7d5f4a5d7d9963f20039ca49c3e 246 Pfam PF00486 Transcriptional regulatory protein, C terminal 159 227 3.2E-19 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDC59_RS22745 4752c7d5f4a5d7d9963f20039ca49c3e 246 SMART SM00448 1 124 5.5E-34 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS22745 4752c7d5f4a5d7d9963f20039ca49c3e 246 SMART SM00862 157 228 8.2E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDC59_RS22745 4752c7d5f4a5d7d9963f20039ca49c3e 246 Pfam PF00072 Response regulator receiver domain 3 124 2.4E-23 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS22745 4752c7d5f4a5d7d9963f20039ca49c3e 246 Gene3D G3DSA:3.40.50.2300 1 127 5.2E-32 T 29-03-2018 CDC59_RS22745 4752c7d5f4a5d7d9963f20039ca49c3e 246 SUPERFAMILY SSF52172 1 175 1.96E-34 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS21755 ac3635da152114ede54a1e2c42e1617a 449 SUPERFAMILY SSF46626 62 232 1.47E-26 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS21755 ac3635da152114ede54a1e2c42e1617a 449 SUPERFAMILY SSF46626 233 301 6.91E-33 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS21755 ac3635da152114ede54a1e2c42e1617a 449 SUPERFAMILY SSF46626 332 431 6.91E-33 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS21755 ac3635da152114ede54a1e2c42e1617a 449 Pfam PF03150 Di-haem cytochrome c peroxidase 71 250 1.7E-31 T 29-03-2018 IPR004852 Di-haem cytochrome c peroxidase GO:0016491|GO:0055114 CDC59_RS21755 ac3635da152114ede54a1e2c42e1617a 449 Gene3D G3DSA:1.10.760.10 59 240 2.7E-26 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS21755 ac3635da152114ede54a1e2c42e1617a 449 Pfam PF00034 Cytochrome c 259 430 5.1E-5 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS21755 ac3635da152114ede54a1e2c42e1617a 449 Gene3D G3DSA:1.10.760.10 241 447 5.3E-31 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS01775 b97d1835a6dd03d35eed8360c721ad2f 131 Gene3D G3DSA:3.10.450.50 1 126 1.5E-22 T 29-03-2018 CDC59_RS01775 b97d1835a6dd03d35eed8360c721ad2f 131 TIGRFAM TIGR02246 TIGR02246: conserved hypothetical protein 3 126 4.0E-34 T 29-03-2018 IPR011944 Steroid delta5-4-isomerase KEGG: 00140+5.3.3.1|KEGG: 00984+5.3.3.1|MetaCyc: PWY-2582|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-699|MetaCyc: PWY-7299 CDC59_RS01775 b97d1835a6dd03d35eed8360c721ad2f 131 Pfam PF14534 Domain of unknown function (DUF4440) 8 117 4.5E-16 T 29-03-2018 IPR027843 Domain of unknown function DUF4440 CDC59_RS01775 b97d1835a6dd03d35eed8360c721ad2f 131 SUPERFAMILY SSF54427 1 120 1.87E-24 T 29-03-2018 IPR032710 NTF2-like domain CDC59_RS03040 6cbe211e685a68cb4beff513573553fd 316 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 5 312 3.9E-96 T 29-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 CDC59_RS03040 6cbe211e685a68cb4beff513573553fd 316 Gene3D G3DSA:3.40.1190.20 45 316 7.5E-47 T 29-03-2018 IPR029056 Ribokinase-like CDC59_RS03040 6cbe211e685a68cb4beff513573553fd 316 Gene3D G3DSA:2.20.150.10 12 44 4.1E-11 T 29-03-2018 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain CDC59_RS03040 6cbe211e685a68cb4beff513573553fd 316 Pfam PF00294 pfkB family carbohydrate kinase 19 298 6.9E-53 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB CDC59_RS03040 6cbe211e685a68cb4beff513573553fd 316 SUPERFAMILY SSF53613 5 301 3.27E-70 T 29-03-2018 IPR029056 Ribokinase-like CDC59_RS03040 6cbe211e685a68cb4beff513573553fd 316 PIRSF PIRSF000535 2 315 2.4E-88 T 29-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 CDC59_RS03040 6cbe211e685a68cb4beff513573553fd 316 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 5 311 9.9E-96 T 29-03-2018 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 CDC59_RS03040 6cbe211e685a68cb4beff513573553fd 316 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 253 266 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CDC59_RS14750 d0725fba61dfa4db959907983a2738d1 294 Gene3D G3DSA:3.30.420.40 108 289 6.7E-54 T 29-03-2018 CDC59_RS14750 d0725fba61dfa4db959907983a2738d1 294 SUPERFAMILY SSF53067 13 141 5.34E-23 T 29-03-2018 CDC59_RS14750 d0725fba61dfa4db959907983a2738d1 294 SUPERFAMILY SSF53067 145 281 4.21E-28 T 29-03-2018 CDC59_RS14750 d0725fba61dfa4db959907983a2738d1 294 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 13 279 4.8E-24 T 29-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CDC59_RS14750 d0725fba61dfa4db959907983a2738d1 294 Pfam PF03309 Type III pantothenate kinase 13 235 3.1E-59 T 29-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CDC59_RS14750 d0725fba61dfa4db959907983a2738d1 294 Hamap MF_01274 Type III pantothenate kinase [coaX]. 12 284 19.504 T 29-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CDC59_RS01180 1e5a18e8dd0eff20213e95e819107b30 115 PRINTS PR00606 Class ID cytochrome C signature 50 63 6.0E-20 T 29-03-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 CDC59_RS01180 1e5a18e8dd0eff20213e95e819107b30 115 PRINTS PR00606 Class ID cytochrome C signature 73 86 6.0E-20 T 29-03-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 CDC59_RS01180 1e5a18e8dd0eff20213e95e819107b30 115 PRINTS PR00606 Class ID cytochrome C signature 35 48 6.0E-20 T 29-03-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 CDC59_RS01180 1e5a18e8dd0eff20213e95e819107b30 115 PRINTS PR00606 Class ID cytochrome C signature 88 98 6.0E-20 T 29-03-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 CDC59_RS01180 1e5a18e8dd0eff20213e95e819107b30 115 PRINTS PR00606 Class ID cytochrome C signature 100 110 6.0E-20 T 29-03-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 CDC59_RS01180 1e5a18e8dd0eff20213e95e819107b30 115 Gene3D G3DSA:1.10.760.10 31 110 1.8E-11 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS01180 1e5a18e8dd0eff20213e95e819107b30 115 SUPERFAMILY SSF46626 33 109 6.86E-16 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS01180 1e5a18e8dd0eff20213e95e819107b30 115 Pfam PF00034 Cytochrome c 30 109 3.4E-4 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS03315 051587193b968d31c370027cb094d60b 686 SMART SM00091 237 305 0.0017 T 29-03-2018 IPR000014 PAS domain CDC59_RS03315 051587193b968d31c370027cb094d60b 686 SUPERFAMILY SSF47384 423 505 1.71E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS03315 051587193b968d31c370027cb094d60b 686 SMART SM00388 431 505 2.1E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS03315 051587193b968d31c370027cb094d60b 686 Gene3D G3DSA:3.30.565.10 487 660 4.2E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS03315 051587193b968d31c370027cb094d60b 686 SUPERFAMILY SSF55874 506 645 1.31E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS03315 051587193b968d31c370027cb094d60b 686 Gene3D G3DSA:1.10.287.130 420 486 3.7E-14 T 29-03-2018 CDC59_RS03315 051587193b968d31c370027cb094d60b 686 Pfam PF00512 His Kinase A (phospho-acceptor) domain 431 502 1.6E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS03315 051587193b968d31c370027cb094d60b 686 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 555 644 1.3E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS03315 051587193b968d31c370027cb094d60b 686 SUPERFAMILY SSF55785 228 309 2.97E-7 T 29-03-2018 IPR000014 PAS domain CDC59_RS03315 051587193b968d31c370027cb094d60b 686 Pfam PF13188 PAS domain 233 305 6.7E-10 T 29-03-2018 IPR000014 PAS domain CDC59_RS03315 051587193b968d31c370027cb094d60b 686 Gene3D G3DSA:3.30.450.20 215 355 6.8E-10 T 29-03-2018 CDC59_RS03315 051587193b968d31c370027cb094d60b 686 SMART SM00387 554 682 4.0E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS11965 74bd347d8cbc8acf2335baa3b6a2f966 278 Gene3D G3DSA:3.40.190.10 24 117 7.6E-6 T 29-03-2018 CDC59_RS11965 74bd347d8cbc8acf2335baa3b6a2f966 278 Pfam PF12849 PBP superfamily domain 30 248 7.9E-26 T 29-03-2018 IPR024370 PBP domain CDC59_RS11965 74bd347d8cbc8acf2335baa3b6a2f966 278 Gene3D G3DSA:3.40.190.10 118 206 3.5E-40 T 29-03-2018 CDC59_RS11965 74bd347d8cbc8acf2335baa3b6a2f966 278 SUPERFAMILY SSF53850 28 258 3.16E-29 T 29-03-2018 CDC59_RS11965 74bd347d8cbc8acf2335baa3b6a2f966 278 Gene3D G3DSA:3.40.190.10 207 273 9.1E-23 T 29-03-2018 CDC59_RS06510 bb20b0fd616717db1f5ae61b8bb85030 905 SUPERFAMILY SSF55486 210 471 2.64E-72 T 29-03-2018 CDC59_RS06510 bb20b0fd616717db1f5ae61b8bb85030 905 Gene3D G3DSA:2.60.40.1730 17 198 7.8E-25 T 29-03-2018 CDC59_RS06510 bb20b0fd616717db1f5ae61b8bb85030 905 TIGRFAM TIGR02414 pepN_proteo: aminopeptidase N 14 904 0.0 T 29-03-2018 IPR012779 Peptidase M1, alanyl aminopeptidase GO:0008270 CDC59_RS06510 bb20b0fd616717db1f5ae61b8bb85030 905 Gene3D G3DSA:1.25.50.10 577 905 7.5E-140 T 29-03-2018 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal CDC59_RS06510 bb20b0fd616717db1f5ae61b8bb85030 905 SUPERFAMILY SSF63737 10 197 1.57E-41 T 29-03-2018 CDC59_RS06510 bb20b0fd616717db1f5ae61b8bb85030 905 Gene3D G3DSA:1.10.390.10 285 463 2.6E-49 T 29-03-2018 CDC59_RS06510 bb20b0fd616717db1f5ae61b8bb85030 905 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 263 273 1.3E-9 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CDC59_RS06510 bb20b0fd616717db1f5ae61b8bb85030 905 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 181 196 1.3E-9 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CDC59_RS06510 bb20b0fd616717db1f5ae61b8bb85030 905 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 131 146 1.3E-9 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CDC59_RS06510 bb20b0fd616717db1f5ae61b8bb85030 905 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 318 330 1.3E-9 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CDC59_RS06510 bb20b0fd616717db1f5ae61b8bb85030 905 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 299 314 1.3E-9 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CDC59_RS06510 bb20b0fd616717db1f5ae61b8bb85030 905 Pfam PF17432 Domain of unknown function (DUF3458_C) ARM repeats 580 905 8.7E-131 T 29-03-2018 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal CDC59_RS06510 bb20b0fd616717db1f5ae61b8bb85030 905 Pfam PF01433 Peptidase family M1 domain 215 457 1.5E-51 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CDC59_RS06510 bb20b0fd616717db1f5ae61b8bb85030 905 Pfam PF11940 Domain of unknown function (DUF3458) Ig-like fold 464 575 1.9E-26 T 29-03-2018 IPR035414 Peptidase M1, alanyl aminopeptidase, Ig-like fold CDC59_RS21810 d3fee12a284351f904458d8f01766041 734 SMART SM00382 511 697 5.4E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS21810 d3fee12a284351f904458d8f01766041 734 Gene3D G3DSA:3.40.50.300 483 714 5.2E-54 T 29-03-2018 CDC59_RS21810 d3fee12a284351f904458d8f01766041 734 TIGRFAM TIGR03375 type_I_sec_LssB: type I secretion system ATPase 21 713 2.1E-220 T 29-03-2018 IPR017750 ATPase, type I secretion system CDC59_RS21810 d3fee12a284351f904458d8f01766041 734 Pfam PF00005 ABC transporter 504 651 3.2E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS21810 d3fee12a284351f904458d8f01766041 734 SUPERFAMILY SSF90123 158 471 3.01E-44 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CDC59_RS21810 d3fee12a284351f904458d8f01766041 734 SUPERFAMILY SSF52540 475 709 3.38E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS21810 d3fee12a284351f904458d8f01766041 734 Gene3D G3DSA:1.20.1560.10 157 475 2.4E-32 T 29-03-2018 CDC59_RS21810 d3fee12a284351f904458d8f01766041 734 Gene3D G3DSA:3.90.70.10 16 124 9.5E-6 T 29-03-2018 CDC59_RS21810 d3fee12a284351f904458d8f01766041 734 Pfam PF00664 ABC transporter transmembrane region 175 433 1.9E-19 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CDC59_RS21810 d3fee12a284351f904458d8f01766041 734 ProSitePatterns PS00211 ABC transporters family signature. 623 637 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS03190 af45f5e3b3c4b34b4c35d2a0aa814f99 294 Pfam PF05673 Protein of unknown function (DUF815) 31 287 4.2E-105 T 29-03-2018 IPR008533 Domain of unknown function DUF815 CDC59_RS03190 af45f5e3b3c4b34b4c35d2a0aa814f99 294 SUPERFAMILY SSF52540 38 195 1.8E-28 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS03190 af45f5e3b3c4b34b4c35d2a0aa814f99 294 Gene3D G3DSA:3.40.50.300 70 198 2.3E-12 T 29-03-2018 CDC59_RS06255 207c22fc1ac067e0f8eeb3165b80c6ba 205 TIGRFAM TIGR00172 maf: septum formation protein Maf 8 198 8.4E-46 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 CDC59_RS06255 207c22fc1ac067e0f8eeb3165b80c6ba 205 SUPERFAMILY SSF52972 7 200 2.03E-56 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CDC59_RS06255 207c22fc1ac067e0f8eeb3165b80c6ba 205 PIRSF PIRSF006305 1 205 4.3E-49 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 CDC59_RS06255 207c22fc1ac067e0f8eeb3165b80c6ba 205 Pfam PF02545 Maf-like protein 8 200 8.2E-52 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 CDC59_RS06255 207c22fc1ac067e0f8eeb3165b80c6ba 205 Hamap MF_00528 Septum formation protein Maf [maf]. 8 205 31.243 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 CDC59_RS06255 207c22fc1ac067e0f8eeb3165b80c6ba 205 Gene3D G3DSA:3.90.950.10 7 205 2.9E-64 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CDC59_RS09235 82ff1b6c93e4b3744e14336d6e24313d 599 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 481 500 4.2E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS09235 82ff1b6c93e4b3744e14336d6e24313d 599 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 461 469 4.2E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS09235 82ff1b6c93e4b3744e14336d6e24313d 599 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 407 418 4.2E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS09235 82ff1b6c93e4b3744e14336d6e24313d 599 SUPERFAMILY SSF53474 19 306 1.43E-46 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS09235 82ff1b6c93e4b3744e14336d6e24313d 599 Gene3D G3DSA:3.40.50.720 308 597 4.7E-56 T 29-03-2018 CDC59_RS09235 82ff1b6c93e4b3744e14336d6e24313d 599 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 407 418 4.5E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS09235 82ff1b6c93e4b3744e14336d6e24313d 599 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 481 500 4.5E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS09235 82ff1b6c93e4b3744e14336d6e24313d 599 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 502 519 4.5E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS09235 82ff1b6c93e4b3744e14336d6e24313d 599 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 333 350 4.5E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS09235 82ff1b6c93e4b3744e14336d6e24313d 599 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 455 471 4.5E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS09235 82ff1b6c93e4b3744e14336d6e24313d 599 Pfam PF00561 alpha/beta hydrolase fold 44 152 7.8E-19 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS09235 82ff1b6c93e4b3744e14336d6e24313d 599 SUPERFAMILY SSF51735 328 593 8.53E-64 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS09235 82ff1b6c93e4b3744e14336d6e24313d 599 Gene3D G3DSA:3.40.50.1820 21 307 1.4E-35 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS09235 82ff1b6c93e4b3744e14336d6e24313d 599 Pfam PF00106 short chain dehydrogenase 332 521 6.2E-49 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS09235 82ff1b6c93e4b3744e14336d6e24313d 599 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 468 496 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CDC59_RS15870 091f7afa5fd795c1b87f003a3b0f2922 329 SUPERFAMILY SSF56349 121 324 4.71E-50 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CDC59_RS15870 091f7afa5fd795c1b87f003a3b0f2922 329 TIGRFAM TIGR02224 recomb_XerC: tyrosine recombinase XerC 22 328 7.0E-106 T 29-03-2018 IPR011931 Tyrosine recombinase XerC GO:0003677|GO:0006310|GO:0007049|GO:0007059|GO:0015074|GO:0051301 CDC59_RS15870 091f7afa5fd795c1b87f003a3b0f2922 329 Pfam PF00589 Phage integrase family 128 312 1.5E-39 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CDC59_RS15870 091f7afa5fd795c1b87f003a3b0f2922 329 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 18 326 58.716 T 29-03-2018 IPR023009 Tyrosine recombinase XerC/XerD CDC59_RS15870 091f7afa5fd795c1b87f003a3b0f2922 329 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 20 102 3.0E-16 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CDC59_RS15870 091f7afa5fd795c1b87f003a3b0f2922 329 SUPERFAMILY SSF47823 17 111 3.14E-12 T 29-03-2018 IPR010998 Integrase, Lambda-type, N-terminal CDC59_RS15870 091f7afa5fd795c1b87f003a3b0f2922 329 Gene3D G3DSA:1.10.150.130 14 129 4.3E-21 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal CDC59_RS15870 091f7afa5fd795c1b87f003a3b0f2922 329 Gene3D G3DSA:1.10.443.10 130 320 9.6E-43 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CDC59_RS16930 55619b5668ed75c2c4c12db2d4a35ba4 749 PIRSF PIRSF036389 22 749 9.7E-223 T 29-03-2018 IPR012368 Oxidoreductase molybdopterin-binding subunit, IorB-related CDC59_RS16930 55619b5668ed75c2c4c12db2d4a35ba4 749 Gene3D G3DSA:3.30.365.10 347 452 2.3E-26 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CDC59_RS16930 55619b5668ed75c2c4c12db2d4a35ba4 749 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 30 56 6.1E-4 T 29-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal CDC59_RS16930 55619b5668ed75c2c4c12db2d4a35ba4 749 SUPERFAMILY SSF56003 41 262 2.02E-39 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CDC59_RS16930 55619b5668ed75c2c4c12db2d4a35ba4 749 SMART SM01008 229 312 5.4E-11 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CDC59_RS16930 55619b5668ed75c2c4c12db2d4a35ba4 749 Gene3D G3DSA:3.30.365.10 615 749 2.1E-22 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CDC59_RS16930 55619b5668ed75c2c4c12db2d4a35ba4 749 Gene3D G3DSA:3.90.1170.50 207 346 7.0E-33 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CDC59_RS16930 55619b5668ed75c2c4c12db2d4a35ba4 749 SUPERFAMILY SSF56003 342 746 1.31E-111 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CDC59_RS16930 55619b5668ed75c2c4c12db2d4a35ba4 749 Gene3D G3DSA:3.30.365.10 453 614 1.6E-35 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CDC59_RS16930 55619b5668ed75c2c4c12db2d4a35ba4 749 Gene3D G3DSA:3.30.365.10 42 206 6.9E-36 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CDC59_RS16930 55619b5668ed75c2c4c12db2d4a35ba4 749 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 337 588 3.3E-26 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CDC59_RS16930 55619b5668ed75c2c4c12db2d4a35ba4 749 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 621 701 2.6E-6 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CDC59_RS16930 55619b5668ed75c2c4c12db2d4a35ba4 749 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 46 212 2.9E-11 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CDC59_RS13220 9cc4c362b1ca85d23a2409dc8a74f28b 729 Pfam PF00593 TonB dependent receptor 270 726 3.3E-40 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CDC59_RS13220 9cc4c362b1ca85d23a2409dc8a74f28b 729 SUPERFAMILY SSF56935 45 729 1.31E-82 T 29-03-2018 CDC59_RS13220 9cc4c362b1ca85d23a2409dc8a74f28b 729 Gene3D G3DSA:2.170.130.10 45 182 4.6E-12 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CDC59_RS13220 9cc4c362b1ca85d23a2409dc8a74f28b 729 Pfam PF07715 TonB-dependent Receptor Plug Domain 74 170 1.1E-4 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CDC59_RS13220 9cc4c362b1ca85d23a2409dc8a74f28b 729 Gene3D G3DSA:2.40.170.20 186 729 5.4E-69 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CDC59_RS02685 354941128447a2cd3f9cbfec6a8bce2b 141 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 3 137 1.4E-40 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CDC59_RS02685 354941128447a2cd3f9cbfec6a8bce2b 141 SUPERFAMILY SSF81330 12 132 1.57E-33 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CDC59_RS02685 354941128447a2cd3f9cbfec6a8bce2b 141 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 13 26 - T 29-03-2018 IPR019823 Large-conductance mechanosensitive channel, conserved site CDC59_RS02685 354941128447a2cd3f9cbfec6a8bce2b 141 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 6 20 2.0E-10 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CDC59_RS02685 354941128447a2cd3f9cbfec6a8bce2b 141 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 94 102 2.0E-10 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CDC59_RS02685 354941128447a2cd3f9cbfec6a8bce2b 141 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 103 112 2.0E-10 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CDC59_RS02685 354941128447a2cd3f9cbfec6a8bce2b 141 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 4 138 4.9E-36 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CDC59_RS02685 354941128447a2cd3f9cbfec6a8bce2b 141 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 3 140 24.559 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CDC59_RS01610 1a6c94027bbf3e689cf2f41ddb77cfeb 209 SMART SM00530 23 78 6.7E-16 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDC59_RS01610 1a6c94027bbf3e689cf2f41ddb77cfeb 209 Gene3D G3DSA:1.10.260.40 10 85 5.8E-20 T 29-03-2018 CDC59_RS01610 1a6c94027bbf3e689cf2f41ddb77cfeb 209 Gene3D G3DSA:2.60.120.10 88 202 2.5E-12 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CDC59_RS01610 1a6c94027bbf3e689cf2f41ddb77cfeb 209 SUPERFAMILY SSF51182 71 200 1.85E-19 T 29-03-2018 IPR011051 RmlC-like cupin domain CDC59_RS01610 1a6c94027bbf3e689cf2f41ddb77cfeb 209 SUPERFAMILY SSF47413 18 85 2.63E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDC59_RS01610 1a6c94027bbf3e689cf2f41ddb77cfeb 209 Pfam PF01381 Helix-turn-helix 24 76 7.4E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDC59_RS00205 1d88f07497a2eeb05732573fa45da286 310 Hamap MF_00082_B Acetylglutamate kinase [argB]. 41 309 35.709 T 29-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CDC59_RS00205 1d88f07497a2eeb05732573fa45da286 310 PIRSF PIRSF000728 15 309 5.0E-103 T 29-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CDC59_RS00205 1d88f07497a2eeb05732573fa45da286 310 Gene3D G3DSA:3.40.1160.10 14 310 2.4E-70 T 29-03-2018 CDC59_RS00205 1d88f07497a2eeb05732573fa45da286 310 TIGRFAM TIGR00761 argB: acetylglutamate kinase 44 284 1.4E-74 T 29-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CDC59_RS00205 1d88f07497a2eeb05732573fa45da286 310 Hamap MF_00082_A Acetylglutamate kinase [argB]. 44 294 28.796 T 29-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CDC59_RS00205 1d88f07497a2eeb05732573fa45da286 310 SUPERFAMILY SSF53633 26 309 9.16E-89 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CDC59_RS00205 1d88f07497a2eeb05732573fa45da286 310 Pfam PF00696 Amino acid kinase family 43 286 2.3E-44 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CDC59_RS10985 d9957f0f9e1aa4227f65daeba0574b46 510 Gene3D G3DSA:3.10.350.10 328 383 0.0015 T 29-03-2018 CDC59_RS10985 d9957f0f9e1aa4227f65daeba0574b46 510 SUPERFAMILY SSF54106 414 455 1.7E-5 T 29-03-2018 IPR018392 LysM domain CDC59_RS10985 d9957f0f9e1aa4227f65daeba0574b46 510 Gene3D G3DSA:3.10.350.10 408 457 6.8E-8 T 29-03-2018 CDC59_RS10985 d9957f0f9e1aa4227f65daeba0574b46 510 Gene3D G3DSA:1.10.530.10 48 249 2.8E-35 T 29-03-2018 CDC59_RS10985 d9957f0f9e1aa4227f65daeba0574b46 510 Pfam PF01464 Transglycosylase SLT domain 111 217 4.8E-26 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 CDC59_RS10985 d9957f0f9e1aa4227f65daeba0574b46 510 Pfam PF01476 LysM domain 336 378 0.018 T 29-03-2018 IPR018392 LysM domain CDC59_RS10985 d9957f0f9e1aa4227f65daeba0574b46 510 Pfam PF01476 LysM domain 418 447 2.4E-5 T 29-03-2018 IPR018392 LysM domain CDC59_RS10985 d9957f0f9e1aa4227f65daeba0574b46 510 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 125 153 - T 29-03-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 CDC59_RS10985 d9957f0f9e1aa4227f65daeba0574b46 510 SUPERFAMILY SSF53955 104 264 1.19E-42 T 29-03-2018 IPR023346 Lysozyme-like domain CDC59_RS10985 d9957f0f9e1aa4227f65daeba0574b46 510 SMART SM00257 334 378 0.91 T 29-03-2018 IPR018392 LysM domain CDC59_RS10985 d9957f0f9e1aa4227f65daeba0574b46 510 SMART SM00257 411 456 0.19 T 29-03-2018 IPR018392 LysM domain CDC59_RS06520 727aace7eb4e23ced4033b46300ba24d 773 SMART SM00919 179 416 2.9E-140 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CDC59_RS06520 727aace7eb4e23ced4033b46300ba24d 773 Gene3D G3DSA:3.40.50.720 177 461 4.1E-86 T 29-03-2018 CDC59_RS06520 727aace7eb4e23ced4033b46300ba24d 773 SUPERFAMILY SSF53659 445 769 5.35E-91 T 29-03-2018 CDC59_RS06520 727aace7eb4e23ced4033b46300ba24d 773 Gene3D G3DSA:3.40.50.10380 21 176 2.1E-35 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CDC59_RS06520 727aace7eb4e23ced4033b46300ba24d 773 Gene3D G3DSA:3.40.718.10 462 735 7.3E-51 T 29-03-2018 CDC59_RS06520 727aace7eb4e23ced4033b46300ba24d 773 Pfam PF03949 Malic enzyme, NAD binding domain 181 375 1.1E-23 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CDC59_RS06520 727aace7eb4e23ced4033b46300ba24d 773 SUPERFAMILY SSF53223 26 177 1.37E-51 T 29-03-2018 CDC59_RS06520 727aace7eb4e23ced4033b46300ba24d 773 Pfam PF00390 Malic enzyme, N-terminal domain 35 167 5.5E-27 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CDC59_RS06520 727aace7eb4e23ced4033b46300ba24d 773 SUPERFAMILY SSF51735 179 468 3.07E-86 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS06520 727aace7eb4e23ced4033b46300ba24d 773 PIRSF PIRSF036684 14 773 0.0 T 29-03-2018 IPR012188 NAD(P)-dependent malic enzyme GO:0004470|GO:0006108|GO:0046872 KEGG: 00620+1.1.1.40|KEGG: 00710+1.1.1.40|MetaCyc: PWY-241|MetaCyc: PWY-7117 CDC59_RS06520 727aace7eb4e23ced4033b46300ba24d 773 Pfam PF01515 Phosphate acetyl/butaryl transferase 445 766 9.8E-96 T 29-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CDC59_RS06520 727aace7eb4e23ced4033b46300ba24d 773 SMART SM01274 34 167 3.8E-78 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CDC59_RS01760 d5fea2a22ebe1580c9f1d0ffec6138ec 162 SMART SM00344 6 120 5.8E-40 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CDC59_RS01760 d5fea2a22ebe1580c9f1d0ffec6138ec 162 Pfam PF13412 Winged helix-turn-helix DNA-binding 6 53 2.4E-22 T 29-03-2018 CDC59_RS01760 d5fea2a22ebe1580c9f1d0ffec6138ec 162 Gene3D G3DSA:1.10.10.10 6 57 1.6E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS01760 d5fea2a22ebe1580c9f1d0ffec6138ec 162 SUPERFAMILY SSF54909 66 160 2.01E-21 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CDC59_RS01760 d5fea2a22ebe1580c9f1d0ffec6138ec 162 Gene3D G3DSA:3.30.70.920 58 157 3.6E-36 T 29-03-2018 CDC59_RS01760 d5fea2a22ebe1580c9f1d0ffec6138ec 162 ProSitePatterns PS00519 AsnC-type HTH domain signature. 24 50 - T 29-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site CDC59_RS01760 d5fea2a22ebe1580c9f1d0ffec6138ec 162 Pfam PF01037 Lrp/AsnC ligand binding domain 72 151 3.2E-25 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CDC59_RS01760 d5fea2a22ebe1580c9f1d0ffec6138ec 162 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 6 22 2.2E-18 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CDC59_RS01760 d5fea2a22ebe1580c9f1d0ffec6138ec 162 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 33 52 2.2E-18 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CDC59_RS01760 d5fea2a22ebe1580c9f1d0ffec6138ec 162 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 22 33 2.2E-18 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CDC59_RS01760 d5fea2a22ebe1580c9f1d0ffec6138ec 162 SUPERFAMILY SSF46785 5 65 1.07E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS20935 9e8ad5f6398a8aeae89718bcfd7e734e 3217 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2901 2916 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CDC59_RS20935 9e8ad5f6398a8aeae89718bcfd7e734e 3217 Gene3D G3DSA:3.40.50.1820 2950 3208 2.8E-11 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS20935 9e8ad5f6398a8aeae89718bcfd7e734e 3217 Gene3D G3DSA:3.40.366.10 731 854 1.1E-20 T 29-03-2018 CDC59_RS20935 9e8ad5f6398a8aeae89718bcfd7e734e 3217 SUPERFAMILY SSF51735 1582 1790 5.76E-28 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS20935 9e8ad5f6398a8aeae89718bcfd7e734e 3217 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1890 1905 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CDC59_RS20935 9e8ad5f6398a8aeae89718bcfd7e734e 3217 Pfam PF00668 Condensation domain 2045 2271 3.5E-25 T 29-03-2018 IPR001242 Condensation domain CDC59_RS20935 9e8ad5f6398a8aeae89718bcfd7e734e 3217 Gene3D G3DSA:1.10.1200.10 1839 1943 1.2E-15 T 29-03-2018 CDC59_RS20935 9e8ad5f6398a8aeae89718bcfd7e734e 3217 Gene3D G3DSA:3.40.47.10 19 287 4.5E-65 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS20935 9e8ad5f6398a8aeae89718bcfd7e734e 3217 Pfam PF00698 Acyl transferase domain 552 846 6.9E-50 T 29-03-2018 IPR014043 Acyl transferase CDC59_RS20935 9e8ad5f6398a8aeae89718bcfd7e734e 3217 SUPERFAMILY SSF53474 2949 3193 4.41E-36 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS20935 9e8ad5f6398a8aeae89718bcfd7e734e 3217 Pfam PF08659 KR domain 1585 1760 1.4E-37 T 29-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CDC59_RS20935 9e8ad5f6398a8aeae89718bcfd7e734e 3217 SUPERFAMILY SSF52151 550 677 9.94E-61 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CDC59_RS20935 9e8ad5f6398a8aeae89718bcfd7e734e 3217 SUPERFAMILY SSF52151 738 832 9.94E-61 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CDC59_RS20935 9e8ad5f6398a8aeae89718bcfd7e734e 3217 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1583 1762 7.8E-16 T 29-03-2018 CDC59_RS20935 9e8ad5f6398a8aeae89718bcfd7e734e 3217 SUPERFAMILY SSF55048 675 736 3.14E-9 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CDC59_RS20935 9e8ad5f6398a8aeae89718bcfd7e734e 3217 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 553 844 1.4E-80 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CDC59_RS20935 9e8ad5f6398a8aeae89718bcfd7e734e 3217 Gene3D G3DSA:3.30.559.10 1946 2122 5.4E-19 T 29-03-2018 CDC59_RS20935 9e8ad5f6398a8aeae89718bcfd7e734e 3217 Gene3D G3DSA:3.40.50.150 2584 2809 2.3E-21 T 29-03-2018 CDC59_RS20935 9e8ad5f6398a8aeae89718bcfd7e734e 3217 SUPERFAMILY SSF47336 2873 2942 3.66E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS20935 9e8ad5f6398a8aeae89718bcfd7e734e 3217 SUPERFAMILY SSF52777 1958 2128 2.11E-21 T 29-03-2018 CDC59_RS20935 9e8ad5f6398a8aeae89718bcfd7e734e 3217 SUPERFAMILY SSF52777 2116 2365 3.67E-43 T 29-03-2018 CDC59_RS20935 9e8ad5f6398a8aeae89718bcfd7e734e 3217 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 188 204 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site CDC59_RS20935 9e8ad5f6398a8aeae89718bcfd7e734e 3217 SMART SM00825 Beta-ketoacyl synthase 28 451 7.1E-191 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CDC59_RS20935 9e8ad5f6398a8aeae89718bcfd7e734e 3217 Gene3D G3DSA:3.40.50.150 1030 1274 3.3E-24 T 29-03-2018 CDC59_RS20935 9e8ad5f6398a8aeae89718bcfd7e734e 3217 Gene3D G3DSA:1.10.1200.10 2858 2945 8.0E-13 T 29-03-2018 CDC59_RS20935 9e8ad5f6398a8aeae89718bcfd7e734e 3217 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 403 515 9.4E-15 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CDC59_RS20935 9e8ad5f6398a8aeae89718bcfd7e734e 3217 Pfam PF00550 Phosphopantetheine attachment site 2881 2941 1.7E-6 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS20935 9e8ad5f6398a8aeae89718bcfd7e734e 3217 Pfam PF00550 Phosphopantetheine attachment site 1864 1931 4.4E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS20935 9e8ad5f6398a8aeae89718bcfd7e734e 3217 Pfam PF08242 Methyltransferase domain 2625 2725 7.0E-16 T 29-03-2018 IPR013217 Methyltransferase type 12 CDC59_RS20935 9e8ad5f6398a8aeae89718bcfd7e734e 3217 Pfam PF08242 Methyltransferase domain 1108 1209 1.4E-17 T 29-03-2018 IPR013217 Methyltransferase type 12 CDC59_RS20935 9e8ad5f6398a8aeae89718bcfd7e734e 3217 SUPERFAMILY SSF53335 1069 1265 1.72E-27 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS20935 9e8ad5f6398a8aeae89718bcfd7e734e 3217 Gene3D G3DSA:3.30.70.250 683 730 4.2E-16 T 29-03-2018 CDC59_RS20935 9e8ad5f6398a8aeae89718bcfd7e734e 3217 SUPERFAMILY SSF51735 1407 1566 2.79E-15 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS20935 9e8ad5f6398a8aeae89718bcfd7e734e 3217 SUPERFAMILY SSF53335 2592 2784 4.26E-24 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS20935 9e8ad5f6398a8aeae89718bcfd7e734e 3217 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 284 400 3.8E-38 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CDC59_RS20935 9e8ad5f6398a8aeae89718bcfd7e734e 3217 SUPERFAMILY SSF47336 1860 1972 3.01E-16 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS20935 9e8ad5f6398a8aeae89718bcfd7e734e 3217 Gene3D G3DSA:3.40.47.10 290 449 1.5E-57 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS20935 9e8ad5f6398a8aeae89718bcfd7e734e 3217 SMART SM00823 Phosphopantetheine attachment site 2878 2935 0.1 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CDC59_RS20935 9e8ad5f6398a8aeae89718bcfd7e734e 3217 SMART SM00823 Phosphopantetheine attachment site 1863 1935 6.0E-7 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CDC59_RS20935 9e8ad5f6398a8aeae89718bcfd7e734e 3217 Pfam PF00975 Thioesterase domain 2967 3055 2.6E-17 T 29-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CDC59_RS20935 9e8ad5f6398a8aeae89718bcfd7e734e 3217 Gene3D G3DSA:3.40.50.720 1577 1817 6.3E-30 T 29-03-2018 CDC59_RS20935 9e8ad5f6398a8aeae89718bcfd7e734e 3217 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 26 275 2.0E-68 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CDC59_RS20935 9e8ad5f6398a8aeae89718bcfd7e734e 3217 SUPERFAMILY SSF53901 171 393 3.74E-77 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS20935 9e8ad5f6398a8aeae89718bcfd7e734e 3217 SUPERFAMILY SSF53901 22 142 3.74E-77 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS20935 9e8ad5f6398a8aeae89718bcfd7e734e 3217 SUPERFAMILY SSF53901 427 446 3.74E-77 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS20935 9e8ad5f6398a8aeae89718bcfd7e734e 3217 Gene3D G3DSA:3.40.366.10 549 682 2.1E-38 T 29-03-2018 CDC59_RS21575 1fc4a3477235cfcfeb4828c013dd7e65 156 SUPERFAMILY SSF46785 11 150 8.67E-34 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS21575 1fc4a3477235cfcfeb4828c013dd7e65 156 SMART SM00347 39 138 6.9E-24 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS21575 1fc4a3477235cfcfeb4828c013dd7e65 156 Pfam PF01047 MarR family 46 104 4.6E-17 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS21575 1fc4a3477235cfcfeb4828c013dd7e65 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 99 115 3.6E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS21575 1fc4a3477235cfcfeb4828c013dd7e65 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 63 79 3.6E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS21575 1fc4a3477235cfcfeb4828c013dd7e65 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 80 95 3.6E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS21575 1fc4a3477235cfcfeb4828c013dd7e65 156 Gene3D G3DSA:1.10.10.10 4 156 2.8E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS12270 f5d74879d15db931f1331c4160765f95 688 PRINTS PR01041 Methionyl-tRNA synthetase signature 8 21 6.5E-24 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CDC59_RS12270 f5d74879d15db931f1331c4160765f95 688 PRINTS PR01041 Methionyl-tRNA synthetase signature 254 265 6.5E-24 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CDC59_RS12270 f5d74879d15db931f1331c4160765f95 688 PRINTS PR01041 Methionyl-tRNA synthetase signature 387 398 6.5E-24 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CDC59_RS12270 f5d74879d15db931f1331c4160765f95 688 PRINTS PR01041 Methionyl-tRNA synthetase signature 40 54 6.5E-24 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CDC59_RS12270 f5d74879d15db931f1331c4160765f95 688 PRINTS PR01041 Methionyl-tRNA synthetase signature 88 99 6.5E-24 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CDC59_RS12270 f5d74879d15db931f1331c4160765f95 688 PRINTS PR01041 Methionyl-tRNA synthetase signature 293 308 6.5E-24 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CDC59_RS12270 f5d74879d15db931f1331c4160765f95 688 SUPERFAMILY SSF50249 581 687 3.92E-30 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDC59_RS12270 f5d74879d15db931f1331c4160765f95 688 Gene3D G3DSA:3.40.50.620 254 374 5.4E-21 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDC59_RS12270 f5d74879d15db931f1331c4160765f95 688 Pfam PF09334 tRNA synthetases class I (M) 6 399 9.6E-146 T 29-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDC59_RS12270 f5d74879d15db931f1331c4160765f95 688 Gene3D G3DSA:2.20.28.20 140 163 1.3E-15 T 29-03-2018 CDC59_RS12270 f5d74879d15db931f1331c4160765f95 688 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 565 688 2.1E-40 T 29-03-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CDC59_RS12270 f5d74879d15db931f1331c4160765f95 688 Pfam PF08264 Anticodon-binding domain of tRNA 423 502 1.0E-5 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CDC59_RS12270 f5d74879d15db931f1331c4160765f95 688 SUPERFAMILY SSF52374 3 139 1.97E-97 T 29-03-2018 CDC59_RS12270 f5d74879d15db931f1331c4160765f95 688 SUPERFAMILY SSF52374 174 390 1.97E-97 T 29-03-2018 CDC59_RS12270 f5d74879d15db931f1331c4160765f95 688 Pfam PF01588 Putative tRNA binding domain 588 684 1.7E-22 T 29-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 CDC59_RS12270 f5d74879d15db931f1331c4160765f95 688 SUPERFAMILY SSF47323 392 551 3.55E-39 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDC59_RS12270 f5d74879d15db931f1331c4160765f95 688 Gene3D G3DSA:3.40.50.620 2 75 8.4E-22 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDC59_RS12270 f5d74879d15db931f1331c4160765f95 688 Hamap MF_00098 Methionine--tRNA ligase [metG]. 4 550 40.103 T 29-03-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CDC59_RS12270 f5d74879d15db931f1331c4160765f95 688 Gene3D G3DSA:2.170.220.10 164 253 2.9E-17 T 29-03-2018 CDC59_RS12270 f5d74879d15db931f1331c4160765f95 688 Gene3D G3DSA:2.40.50.140 574 688 2.3E-29 T 29-03-2018 CDC59_RS12270 f5d74879d15db931f1331c4160765f95 688 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 6 529 1.7E-166 T 29-03-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CDC59_RS12270 f5d74879d15db931f1331c4160765f95 688 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 13 24 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDC59_RS12270 f5d74879d15db931f1331c4160765f95 688 Gene3D G3DSA:1.10.730.10 376 541 6.7E-36 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDC59_RS12270 f5d74879d15db931f1331c4160765f95 688 SUPERFAMILY SSF57770 140 174 3.79E-12 T 29-03-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CDC59_RS06170 2b925f6be8e1ce6d54bac5f9804e2da2 233 Pfam PF00440 Bacterial regulatory proteins, tetR family 42 86 2.0E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDC59_RS06170 2b925f6be8e1ce6d54bac5f9804e2da2 233 ProSitePatterns PS01081 TetR-type HTH domain signature. 54 84 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CDC59_RS06170 2b925f6be8e1ce6d54bac5f9804e2da2 233 SUPERFAMILY SSF46689 27 114 5.13E-20 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS06170 2b925f6be8e1ce6d54bac5f9804e2da2 233 Gene3D G3DSA:1.10.10.60 10 90 7.9E-21 T 29-03-2018 CDC59_RS06170 2b925f6be8e1ce6d54bac5f9804e2da2 233 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 55 1.3E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDC59_RS06170 2b925f6be8e1ce6d54bac5f9804e2da2 233 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 63 86 1.3E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDC59_RS06170 2b925f6be8e1ce6d54bac5f9804e2da2 233 SUPERFAMILY SSF48498 109 217 1.96E-10 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CDC59_RS06170 2b925f6be8e1ce6d54bac5f9804e2da2 233 Gene3D G3DSA:1.10.357.10 91 224 7.0E-13 T 29-03-2018 CDC59_RS08140 dfc26afa745794ae68e1b109cdfc0243 141 Pfam PF00334 Nucleoside diphosphate kinase 4 135 1.6E-53 T 29-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CDC59_RS08140 dfc26afa745794ae68e1b109cdfc0243 141 SMART SM00562 3 140 4.9E-80 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CDC59_RS08140 dfc26afa745794ae68e1b109cdfc0243 141 SUPERFAMILY SSF54919 1 140 6.29E-56 T 29-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CDC59_RS08140 dfc26afa745794ae68e1b109cdfc0243 141 Gene3D G3DSA:3.30.70.141 1 55 2.4E-17 T 29-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CDC59_RS08140 dfc26afa745794ae68e1b109cdfc0243 141 Gene3D G3DSA:3.30.70.141 56 139 5.4E-30 T 29-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CDC59_RS08140 dfc26afa745794ae68e1b109cdfc0243 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 1.5E-37 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CDC59_RS08140 dfc26afa745794ae68e1b109cdfc0243 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 50 69 1.5E-37 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CDC59_RS08140 dfc26afa745794ae68e1b109cdfc0243 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 70 87 1.5E-37 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CDC59_RS08140 dfc26afa745794ae68e1b109cdfc0243 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 6 28 1.5E-37 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CDC59_RS08140 dfc26afa745794ae68e1b109cdfc0243 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 1.5E-37 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CDC59_RS08140 dfc26afa745794ae68e1b109cdfc0243 141 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 3 138 34.308 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CDC59_RS21040 64cae2da02fec46d0273222076a91e39 467 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 259 296 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CDC59_RS21040 64cae2da02fec46d0273222076a91e39 467 Pfam PF00202 Aminotransferase class-III 37 452 4.1E-91 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CDC59_RS21040 64cae2da02fec46d0273222076a91e39 467 Gene3D G3DSA:3.90.1150.10 2 76 3.0E-9 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS21040 64cae2da02fec46d0273222076a91e39 467 Gene3D G3DSA:3.90.1150.10 335 455 2.1E-17 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS21040 64cae2da02fec46d0273222076a91e39 467 PIRSF PIRSF000521 29 455 1.4E-28 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CDC59_RS21040 64cae2da02fec46d0273222076a91e39 467 SUPERFAMILY SSF53383 17 454 2.74E-115 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS21040 64cae2da02fec46d0273222076a91e39 467 Gene3D G3DSA:3.40.640.10 77 334 4.1E-74 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDC59_RS00690 d530c52cfa475bd447f438045b0962d1 158 Pfam PF09278 MerR, DNA binding 58 118 2.9E-22 T 29-03-2018 IPR015358 Transcription regulator MerR, DNA binding CDC59_RS00690 d530c52cfa475bd447f438045b0962d1 158 ProSitePatterns PS00552 MerR-type HTH domain signature. 17 39 - T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CDC59_RS00690 d530c52cfa475bd447f438045b0962d1 158 Pfam PF00376 MerR family regulatory protein 15 52 3.4E-19 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CDC59_RS00690 d530c52cfa475bd447f438045b0962d1 158 TIGRFAM TIGR02044 CueR: Cu(I)-responsive transcriptional regulator 14 139 7.1E-59 T 29-03-2018 IPR011789 Cu(I)-responsive transcriptional regulator GO:0003677|GO:0003700|GO:0005507|GO:0045893 CDC59_RS00690 d530c52cfa475bd447f438045b0962d1 158 Gene3D G3DSA:1.10.1660.10 70 147 8.6E-21 T 29-03-2018 CDC59_RS00690 d530c52cfa475bd447f438045b0962d1 158 SMART SM00422 14 83 7.4E-33 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CDC59_RS00690 d530c52cfa475bd447f438045b0962d1 158 SUPERFAMILY SSF46955 15 138 1.47E-39 T 29-03-2018 IPR009061 Putative DNA-binding domain CDC59_RS00690 d530c52cfa475bd447f438045b0962d1 158 Gene3D G3DSA:1.10.1660.10 13 69 7.9E-25 T 29-03-2018 CDC59_RS00690 d530c52cfa475bd447f438045b0962d1 158 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 26 1.3E-10 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CDC59_RS00690 d530c52cfa475bd447f438045b0962d1 158 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 50 70 1.3E-10 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CDC59_RS00690 d530c52cfa475bd447f438045b0962d1 158 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 26 39 1.3E-10 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CDC59_RS06685 590fd6c9c68ab22448075646e98b9c22 429 Hamap MF_01202 D-amino acid dehydrogenase [dadA]. 1 410 50.444 T 29-03-2018 IPR023080 D-amino acid dehydrogenase DadA GO:0008718|GO:0019478|GO:0055114 CDC59_RS06685 590fd6c9c68ab22448075646e98b9c22 429 SUPERFAMILY SSF54373 269 359 6.54E-17 T 29-03-2018 CDC59_RS06685 590fd6c9c68ab22448075646e98b9c22 429 Gene3D G3DSA:3.50.50.60 1 424 3.3E-47 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS06685 590fd6c9c68ab22448075646e98b9c22 429 Pfam PF01266 FAD dependent oxidoreductase 3 397 4.8E-73 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CDC59_RS06685 590fd6c9c68ab22448075646e98b9c22 429 SUPERFAMILY SSF51905 107 271 6.86E-53 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS06685 590fd6c9c68ab22448075646e98b9c22 429 SUPERFAMILY SSF51905 1 54 6.86E-53 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS06685 590fd6c9c68ab22448075646e98b9c22 429 SUPERFAMILY SSF51905 359 418 6.86E-53 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS03300 7b597e117dcf5d0b9485d2c6d2dc17c2 478 Pfam PF00448 SRP54-type protein, GTPase domain 121 316 4.5E-72 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CDC59_RS03300 7b597e117dcf5d0b9485d2c6d2dc17c2 478 SMART SM00382 119 321 1.1E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS03300 7b597e117dcf5d0b9485d2c6d2dc17c2 478 SMART SM00962 120 316 3.0E-116 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CDC59_RS03300 7b597e117dcf5d0b9485d2c6d2dc17c2 478 Gene3D G3DSA:1.20.120.140 231 330 1.7E-33 T 29-03-2018 CDC59_RS03300 7b597e117dcf5d0b9485d2c6d2dc17c2 478 Gene3D G3DSA:1.10.260.30 348 453 4.1E-36 T 29-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CDC59_RS03300 7b597e117dcf5d0b9485d2c6d2dc17c2 478 Gene3D G3DSA:3.40.50.300 91 230 5.6E-6 T 29-03-2018 CDC59_RS03300 7b597e117dcf5d0b9485d2c6d2dc17c2 478 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 9.3E-18 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CDC59_RS03300 7b597e117dcf5d0b9485d2c6d2dc17c2 478 Gene3D G3DSA:1.20.120.140 1 90 3.5E-26 T 29-03-2018 CDC59_RS03300 7b597e117dcf5d0b9485d2c6d2dc17c2 478 Pfam PF02978 Signal peptide binding domain 349 448 1.3E-32 T 29-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CDC59_RS03300 7b597e117dcf5d0b9485d2c6d2dc17c2 478 SUPERFAMILY SSF52540 42 378 6.27E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS03300 7b597e117dcf5d0b9485d2c6d2dc17c2 478 SUPERFAMILY SSF47446 349 451 1.57E-34 T 29-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CDC59_RS03300 7b597e117dcf5d0b9485d2c6d2dc17c2 478 TIGRFAM TIGR00959 ffh: signal recognition particle protein 110 450 1.2E-145 T 29-03-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 CDC59_RS03300 7b597e117dcf5d0b9485d2c6d2dc17c2 478 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 460 33.069 T 29-03-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 CDC59_RS03300 7b597e117dcf5d0b9485d2c6d2dc17c2 478 SMART SM00963 1 86 1.5E-29 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CDC59_RS08100 2078ed3e36215b0e19cd8fc348bd7fdc 324 SUPERFAMILY SSF51735 116 290 1.86E-48 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS08100 2078ed3e36215b0e19cd8fc348bd7fdc 324 SMART SM00829 10 322 8.7E-47 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CDC59_RS08100 2078ed3e36215b0e19cd8fc348bd7fdc 324 Gene3D G3DSA:3.40.50.720 135 308 8.7E-40 T 29-03-2018 CDC59_RS08100 2078ed3e36215b0e19cd8fc348bd7fdc 324 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 87 6.1E-13 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CDC59_RS08100 2078ed3e36215b0e19cd8fc348bd7fdc 324 SUPERFAMILY SSF50129 1 140 1.34E-41 T 29-03-2018 IPR011032 GroES-like CDC59_RS08100 2078ed3e36215b0e19cd8fc348bd7fdc 324 Pfam PF00107 Zinc-binding dehydrogenase 151 279 6.2E-28 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CDC59_RS08100 2078ed3e36215b0e19cd8fc348bd7fdc 324 Gene3D G3DSA:3.90.180.10 1 134 2.6E-42 T 29-03-2018 CDC59_RS00210 b12a4f8f3c22356cbe4a2555e53af2d6 197 Pfam PF08281 Sigma-70, region 4 130 181 8.6E-11 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS00210 b12a4f8f3c22356cbe4a2555e53af2d6 197 Gene3D G3DSA:1.10.1740.10 5 77 4.0E-15 T 29-03-2018 CDC59_RS00210 b12a4f8f3c22356cbe4a2555e53af2d6 197 SUPERFAMILY SSF88659 117 185 1.4E-12 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS00210 b12a4f8f3c22356cbe4a2555e53af2d6 197 TIGRFAM TIGR02943 Sig70_famx1: RNA polymerase sigma-70 factor, TIGR02943 family 3 192 2.8E-73 T 29-03-2018 IPR014289 RNA polymerase sigma-24-related CDC59_RS00210 b12a4f8f3c22356cbe4a2555e53af2d6 197 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 10 185 3.9E-19 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS00210 b12a4f8f3c22356cbe4a2555e53af2d6 197 SUPERFAMILY SSF88946 8 80 9.42E-14 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS00210 b12a4f8f3c22356cbe4a2555e53af2d6 197 Pfam PF04542 Sigma-70 region 2 10 74 8.2E-11 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS00210 b12a4f8f3c22356cbe4a2555e53af2d6 197 Gene3D G3DSA:1.10.10.10 118 188 1.3E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS12755 51a9b7c5dc3fe7459f2525d4561e8bca 321 Pfam PF03466 LysR substrate binding domain 89 291 1.5E-28 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS12755 51a9b7c5dc3fe7459f2525d4561e8bca 321 Gene3D G3DSA:1.10.10.10 1 82 4.6E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS12755 51a9b7c5dc3fe7459f2525d4561e8bca 321 SUPERFAMILY SSF53850 90 294 1.03E-26 T 29-03-2018 CDC59_RS12755 51a9b7c5dc3fe7459f2525d4561e8bca 321 SUPERFAMILY SSF46785 1 110 7.07E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS12755 51a9b7c5dc3fe7459f2525d4561e8bca 321 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 2.2E-15 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS12755 51a9b7c5dc3fe7459f2525d4561e8bca 321 Gene3D G3DSA:3.40.190.10 176 266 3.9E-9 T 29-03-2018 CDC59_RS12755 51a9b7c5dc3fe7459f2525d4561e8bca 321 Gene3D G3DSA:3.40.190.10 91 175 7.2E-16 T 29-03-2018 CDC59_RS04495 c4134365e176d6ebbb11071626756bf5 275 SUPERFAMILY SSF53448 3 252 2.25E-35 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDC59_RS04495 c4134365e176d6ebbb11071626756bf5 275 Gene3D G3DSA:3.90.550.10 2 274 1.8E-30 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDC59_RS04495 c4134365e176d6ebbb11071626756bf5 275 Pfam PF13641 Glycosyltransferase like family 2 17 232 8.7E-10 T 29-03-2018 CDC59_RS12765 eaa6af08826be73822fb7cef61424e6c 518 SUPERFAMILY SSF103473 272 446 3.27E-39 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS12765 eaa6af08826be73822fb7cef61424e6c 518 SUPERFAMILY SSF103473 492 508 3.27E-39 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS12765 eaa6af08826be73822fb7cef61424e6c 518 SUPERFAMILY SSF103473 28 214 3.27E-39 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS12765 eaa6af08826be73822fb7cef61424e6c 518 Gene3D G3DSA:1.20.1250.20 270 517 2.0E-10 T 29-03-2018 CDC59_RS12765 eaa6af08826be73822fb7cef61424e6c 518 Gene3D G3DSA:1.20.1250.20 10 216 2.6E-25 T 29-03-2018 CDC59_RS12765 eaa6af08826be73822fb7cef61424e6c 518 Pfam PF07690 Major Facilitator Superfamily 31 411 3.4E-29 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDC59_RS00810 e3e5befc7e4816fe53a9d97d2ba6ad99 303 Gene3D G3DSA:1.10.10.730 129 176 1.5E-20 T 29-03-2018 CDC59_RS00810 e3e5befc7e4816fe53a9d97d2ba6ad99 303 Pfam PF02195 ParB-like nuclease domain 36 128 3.2E-27 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CDC59_RS00810 e3e5befc7e4816fe53a9d97d2ba6ad99 303 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 31 212 9.3E-60 T 29-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 CDC59_RS00810 e3e5befc7e4816fe53a9d97d2ba6ad99 303 SUPERFAMILY SSF110849 35 130 1.41E-27 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CDC59_RS00810 e3e5befc7e4816fe53a9d97d2ba6ad99 303 Gene3D G3DSA:3.30.1490.20 231 302 0.028 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CDC59_RS00810 e3e5befc7e4816fe53a9d97d2ba6ad99 303 Gene3D G3DSA:3.90.1530.10 21 128 5.2E-35 T 29-03-2018 CDC59_RS00810 e3e5befc7e4816fe53a9d97d2ba6ad99 303 SUPERFAMILY SSF109709 121 227 1.26E-34 T 29-03-2018 CDC59_RS00810 e3e5befc7e4816fe53a9d97d2ba6ad99 303 SMART SM00470 34 128 1.4E-34 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CDC59_RS08170 ce0b0554b92bbbd4bc8213d8670f373a 211 Gene3D G3DSA:1.25.40.10 41 202 6.3E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS08170 ce0b0554b92bbbd4bc8213d8670f373a 211 Pfam PF09976 Tetratricopeptide repeat-like domain 15 209 3.7E-64 T 29-03-2018 IPR018704 Tetratricopeptide repeat-like domain Reactome: R-HSA-192823|Reactome: R-HSA-381038|Reactome: R-HSA-381426|Reactome: R-HSA-6798695|Reactome: R-HSA-8957275 CDC59_RS08170 ce0b0554b92bbbd4bc8213d8670f373a 211 PIRSF PIRSF006170 1 211 2.3E-57 T 29-03-2018 IPR026039 Uncharacterised protein family UPF0070 CDC59_RS21205 a129477e848f759987081cf932229da9 67 SMART SM00357 3 67 2.2E-32 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 CDC59_RS21205 a129477e848f759987081cf932229da9 67 Gene3D G3DSA:2.40.50.140 1 67 8.8E-30 T 29-03-2018 CDC59_RS21205 a129477e848f759987081cf932229da9 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 1.4E-31 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CDC59_RS21205 a129477e848f759987081cf932229da9 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 29-03-2018 IPR019844 Cold-shock conserved site CDC59_RS21205 a129477e848f759987081cf932229da9 67 PIRSF PIRSF002599 1 67 8.9E-25 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 CDC59_RS21205 a129477e848f759987081cf932229da9 67 PRINTS PR00050 Cold shock protein signature 40 58 9.3E-18 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CDC59_RS21205 a129477e848f759987081cf932229da9 67 PRINTS PR00050 Cold shock protein signature 25 34 9.3E-18 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CDC59_RS21205 a129477e848f759987081cf932229da9 67 PRINTS PR00050 Cold shock protein signature 4 19 9.3E-18 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CDC59_RS21205 a129477e848f759987081cf932229da9 67 SUPERFAMILY SSF50249 1 65 2.79E-26 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDC59_RS14245 8b8dfc100757581b51411062c031af0f 151 SUPERFAMILY SSF55804 1 149 6.54E-45 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CDC59_RS14245 8b8dfc100757581b51411062c031af0f 151 TIGRFAM TIGR01419 nitro_reg_IIA: PTS IIA-like nitrogen-regulatory protein PtsN 4 148 4.5E-43 T 29-03-2018 IPR006320 Phosphotransferase system, IIA-like nitrogen-regulatory protein PtsN GO:0008982|GO:0009401 CDC59_RS14245 8b8dfc100757581b51411062c031af0f 151 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 7 148 2.4E-35 T 29-03-2018 IPR002178 PTS EIIA type-2 domain CDC59_RS14245 8b8dfc100757581b51411062c031af0f 151 Gene3D G3DSA:3.40.930.10 2 150 2.8E-41 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CDC59_RS14245 8b8dfc100757581b51411062c031af0f 151 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 52 68 - T 29-03-2018 IPR002178 PTS EIIA type-2 domain CDC59_RS09140 84d191faae10c17e18feb6dcfec5ccf7 861 Gene3D G3DSA:1.20.120.330 162 309 1.2E-26 T 29-03-2018 CDC59_RS09140 84d191faae10c17e18feb6dcfec5ccf7 861 SUPERFAMILY SSF81301 29 157 1.41E-21 T 29-03-2018 CDC59_RS09140 84d191faae10c17e18feb6dcfec5ccf7 861 Gene3D G3DSA:3.30.460.10 22 161 3.0E-25 T 29-03-2018 CDC59_RS09140 84d191faae10c17e18feb6dcfec5ccf7 861 Gene3D G3DSA:1.10.3090.10 364 626 1.3E-37 T 29-03-2018 CDC59_RS09140 84d191faae10c17e18feb6dcfec5ccf7 861 SUPERFAMILY SSF55021 675 741 5.34E-11 T 29-03-2018 CDC59_RS09140 84d191faae10c17e18feb6dcfec5ccf7 861 SUPERFAMILY SSF81593 170 298 3.22E-9 T 29-03-2018 CDC59_RS09140 84d191faae10c17e18feb6dcfec5ccf7 861 Hamap MF_00277 Bifunctional uridylyltransferase/uridylyl-removing enzyme [glnD]. 1 861 324.419 T 29-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 CDC59_RS09140 84d191faae10c17e18feb6dcfec5ccf7 861 Pfam PF01966 HD domain 442 546 2.2E-9 T 29-03-2018 IPR006674 HD domain CDC59_RS09140 84d191faae10c17e18feb6dcfec5ccf7 861 SUPERFAMILY SSF109604 408 533 5.65E-15 T 29-03-2018 CDC59_RS09140 84d191faae10c17e18feb6dcfec5ccf7 861 TIGRFAM TIGR01693 UTase_glnD: protein-P-II uridylyltransferase 23 859 2.5E-239 T 29-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 CDC59_RS09140 84d191faae10c17e18feb6dcfec5ccf7 861 PIRSF PIRSF006288 1 861 0.0 T 29-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 CDC59_RS09140 84d191faae10c17e18feb6dcfec5ccf7 861 SMART SM00471 437 584 4.9E-4 T 29-03-2018 IPR003607 HD/PDEase domain CDC59_RS09140 84d191faae10c17e18feb6dcfec5ccf7 861 Gene3D G3DSA:3.30.70.260 677 758 9.1E-9 T 29-03-2018 CDC59_RS09140 84d191faae10c17e18feb6dcfec5ccf7 861 Gene3D G3DSA:3.30.70.260 786 861 1.8E-11 T 29-03-2018 CDC59_RS09140 84d191faae10c17e18feb6dcfec5ccf7 861 Pfam PF03445 Putative nucleotidyltransferase DUF294 23 106 6.7E-5 T 29-03-2018 IPR005105 Protein-PII uridylyltransferase, N-terminal GO:0008773 CDC59_RS09140 84d191faae10c17e18feb6dcfec5ccf7 861 SUPERFAMILY SSF55021 788 840 2.37E-9 T 29-03-2018 CDC59_RS09140 84d191faae10c17e18feb6dcfec5ccf7 861 Pfam PF08335 GlnD PII-uridylyltransferase 166 303 1.5E-31 T 29-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 CDC59_RS14825 a658b83fa7ae7b58fc4af0f15a0ff60a 279 SUPERFAMILY SSF53474 6 267 9.59E-69 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS14825 a658b83fa7ae7b58fc4af0f15a0ff60a 279 Gene3D G3DSA:3.40.50.1820 7 271 2.1E-52 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS14825 a658b83fa7ae7b58fc4af0f15a0ff60a 279 Pfam PF00561 alpha/beta hydrolase fold 29 254 1.9E-22 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS14825 a658b83fa7ae7b58fc4af0f15a0ff60a 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 54 69 5.7E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS14825 a658b83fa7ae7b58fc4af0f15a0ff60a 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 98 111 5.7E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS14825 a658b83fa7ae7b58fc4af0f15a0ff60a 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 112 125 5.7E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS14825 a658b83fa7ae7b58fc4af0f15a0ff60a 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 213 227 5.7E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS03845 9377cc48c770da99cc9818860a0f0ef8 166 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 72 88 1.5E-11 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CDC59_RS03845 9377cc48c770da99cc9818860a0f0ef8 166 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 48 64 1.5E-11 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CDC59_RS03845 9377cc48c770da99cc9818860a0f0ef8 166 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 143 161 1.5E-11 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CDC59_RS03845 9377cc48c770da99cc9818860a0f0ef8 166 PIRSF PIRSF005900 7 166 2.0E-48 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CDC59_RS03845 9377cc48c770da99cc9818860a0f0ef8 166 Pfam PF00210 Ferritin-like domain 28 165 7.0E-28 T 29-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 CDC59_RS03845 9377cc48c770da99cc9818860a0f0ef8 166 Gene3D G3DSA:1.20.1260.10 2 166 5.6E-51 T 29-03-2018 IPR012347 Ferritin-related CDC59_RS03845 9377cc48c770da99cc9818860a0f0ef8 166 SUPERFAMILY SSF47240 15 165 6.9E-48 T 29-03-2018 IPR009078 Ferritin-like superfamily CDC59_RS03845 9377cc48c770da99cc9818860a0f0ef8 166 ProSitePatterns PS00819 Dps protein family signature 2. 74 88 - T 29-03-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 CDC59_RS03845 9377cc48c770da99cc9818860a0f0ef8 166 ProSitePatterns PS00818 Dps protein family signature 1. 48 64 - T 29-03-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 CDC59_RS03455 497aa95b52099b231021e3cfcd8b168a 195 SUPERFAMILY SSF64288 16 187 5.49E-40 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CDC59_RS03455 497aa95b52099b231021e3cfcd8b168a 195 Pfam PF04345 Chorismate lyase 29 185 1.4E-22 T 29-03-2018 IPR007440 Chorismate--pyruvate lyase GO:0005737|GO:0006744|GO:0008813 KEGG: 00130+4.1.3.40|MetaCyc: PWY-5755|MetaCyc: PWY-5870|MetaCyc: PWY-6148|MetaCyc: PWY-7742|MetaCyc: PWY-7745 CDC59_RS03455 497aa95b52099b231021e3cfcd8b168a 195 Gene3D G3DSA:3.40.1410.10 8 189 6.3E-39 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CDC59_RS03455 497aa95b52099b231021e3cfcd8b168a 195 Hamap MF_01632 Chorismate pyruvate-lyase [ubiC]. 11 189 24.629 T 29-03-2018 IPR007440 Chorismate--pyruvate lyase GO:0005737|GO:0006744|GO:0008813 KEGG: 00130+4.1.3.40|MetaCyc: PWY-5755|MetaCyc: PWY-5870|MetaCyc: PWY-6148|MetaCyc: PWY-7742|MetaCyc: PWY-7745 CDC59_RS03875 96f6a2bbf7e38e5c02460ee9c001c800 379 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 11 351 3.5E-138 T 29-03-2018 IPR006321 Pilus retraction protein PilT GO:0005524|GO:0006810 CDC59_RS03875 96f6a2bbf7e38e5c02460ee9c001c800 379 Pfam PF00437 Type II/IV secretion system protein 126 277 1.9E-38 T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CDC59_RS03875 96f6a2bbf7e38e5c02460ee9c001c800 379 Gene3D G3DSA:3.30.450.90 10 108 4.1E-19 T 29-03-2018 CDC59_RS03875 96f6a2bbf7e38e5c02460ee9c001c800 379 Gene3D G3DSA:3.40.50.300 282 355 4.9E-12 T 29-03-2018 CDC59_RS03875 96f6a2bbf7e38e5c02460ee9c001c800 379 Gene3D G3DSA:3.40.50.300 125 281 9.6E-26 T 29-03-2018 CDC59_RS03875 96f6a2bbf7e38e5c02460ee9c001c800 379 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 201 215 - T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CDC59_RS03875 96f6a2bbf7e38e5c02460ee9c001c800 379 SUPERFAMILY SSF52540 4 345 4.4E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS20700 20b94c72919c0696dc15558cf6ee3dde 550 Gene3D G3DSA:3.40.50.980 24 203 2.0E-29 T 29-03-2018 CDC59_RS20700 20b94c72919c0696dc15558cf6ee3dde 550 SUPERFAMILY SSF56801 15 538 3.79E-112 T 29-03-2018 CDC59_RS20700 20b94c72919c0696dc15558cf6ee3dde 550 Gene3D G3DSA:3.30.300.30 436 540 1.6E-20 T 29-03-2018 CDC59_RS20700 20b94c72919c0696dc15558cf6ee3dde 550 Pfam PF13193 AMP-binding enzyme C-terminal domain 453 529 3.5E-7 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CDC59_RS20700 20b94c72919c0696dc15558cf6ee3dde 550 Pfam PF00501 AMP-binding enzyme 33 443 1.4E-66 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CDC59_RS20700 20b94c72919c0696dc15558cf6ee3dde 550 ProSitePatterns PS00455 Putative AMP-binding domain signature. 197 208 - T 29-03-2018 IPR020845 AMP-binding, conserved site CDC59_RS20700 20b94c72919c0696dc15558cf6ee3dde 550 Gene3D G3DSA:2.30.38.10 347 435 1.1E-19 T 29-03-2018 CDC59_RS20700 20b94c72919c0696dc15558cf6ee3dde 550 Gene3D G3DSA:3.40.50.980 204 346 4.5E-27 T 29-03-2018 CDC59_RS18230 cf17dc46da1be94976bb458667e9beea 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 1.6E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS18230 cf17dc46da1be94976bb458667e9beea 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 1.6E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS18230 cf17dc46da1be94976bb458667e9beea 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 1.6E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS18230 cf17dc46da1be94976bb458667e9beea 294 Gene3D G3DSA:3.40.190.10 90 180 2.0E-10 T 29-03-2018 CDC59_RS18230 cf17dc46da1be94976bb458667e9beea 294 SUPERFAMILY SSF53850 90 293 3.8E-22 T 29-03-2018 CDC59_RS18230 cf17dc46da1be94976bb458667e9beea 294 SUPERFAMILY SSF46785 6 89 1.24E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS18230 cf17dc46da1be94976bb458667e9beea 294 Gene3D G3DSA:1.10.10.10 2 87 1.1E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS18230 cf17dc46da1be94976bb458667e9beea 294 Gene3D G3DSA:3.40.190.10 181 262 3.1E-6 T 29-03-2018 CDC59_RS18230 cf17dc46da1be94976bb458667e9beea 294 Pfam PF03466 LysR substrate binding domain 89 292 6.4E-19 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS18230 cf17dc46da1be94976bb458667e9beea 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 64 6.4E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS11865 6e4f922b4d0c79f305a8804ca9641d1c 291 Pfam PF01066 CDP-alcohol phosphatidyltransferase 48 111 4.4E-13 T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CDC59_RS11865 6e4f922b4d0c79f305a8804ca9641d1c 291 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 89 111 - T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CDC59_RS11865 6e4f922b4d0c79f305a8804ca9641d1c 291 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 55 191 1.3E-32 T 29-03-2018 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 CDC59_RS15340 036417229c3a9a5da55b409ad3550f74 321 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS15340 036417229c3a9a5da55b409ad3550f74 321 SUPERFAMILY SSF52540 11 236 2.17E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS15340 036417229c3a9a5da55b409ad3550f74 321 SMART SM00382 41 220 1.0E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS15340 036417229c3a9a5da55b409ad3550f74 321 Pfam PF00005 ABC transporter 33 174 1.1E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS15340 036417229c3a9a5da55b409ad3550f74 321 Gene3D G3DSA:3.40.50.300 5 244 3.0E-63 T 29-03-2018 CDC59_RS13800 f526dc05b127b79285677d444f531062 150 Gene3D G3DSA:2.20.25.10 1 23 6.0E-17 T 29-03-2018 CDC59_RS13800 f526dc05b127b79285677d444f531062 150 Gene3D G3DSA:3.30.300.20 24 141 1.0E-28 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CDC59_RS13800 f526dc05b127b79285677d444f531062 150 Pfam PF02566 OsmC-like protein 36 133 1.1E-16 T 29-03-2018 IPR003718 OsmC/Ohr family CDC59_RS13800 f526dc05b127b79285677d444f531062 150 SUPERFAMILY SSF82784 1 138 9.68E-40 T 29-03-2018 IPR003718 OsmC/Ohr family CDC59_RS04450 777df8349192959f39a2c8c1e05067c0 425 Hamap MF_00220_B Dihydroorotase [pyrC]. 2 425 32.651 T 29-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDC59_RS04450 777df8349192959f39a2c8c1e05067c0 425 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 20 422 8.6E-97 T 29-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDC59_RS04450 777df8349192959f39a2c8c1e05067c0 425 Pfam PF01979 Amidohydrolase family 225 420 2.2E-12 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CDC59_RS04450 777df8349192959f39a2c8c1e05067c0 425 SUPERFAMILY SSF51338 1 55 1.19E-28 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CDC59_RS04450 777df8349192959f39a2c8c1e05067c0 425 SUPERFAMILY SSF51338 367 423 1.19E-28 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CDC59_RS04450 777df8349192959f39a2c8c1e05067c0 425 SUPERFAMILY SSF51556 56 367 1.08E-87 T 29-03-2018 IPR032466 Metal-dependent hydrolase CDC59_RS04450 777df8349192959f39a2c8c1e05067c0 425 Gene3D G3DSA:2.30.40.10 1 70 6.6E-15 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CDC59_RS04450 777df8349192959f39a2c8c1e05067c0 425 Gene3D G3DSA:3.20.20.140 71 388 2.0E-78 T 29-03-2018 CDC59_RS15195 a4c244f1afb361182c4d6eda7b5ccb2f 535 Gene3D G3DSA:3.40.50.10770 28 146 1.1E-8 T 29-03-2018 CDC59_RS15195 a4c244f1afb361182c4d6eda7b5ccb2f 535 Gene3D G3DSA:3.40.50.300 179 361 1.2E-21 T 29-03-2018 CDC59_RS15195 a4c244f1afb361182c4d6eda7b5ccb2f 535 SUPERFAMILY SSF52540 186 436 8.79E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS15195 a4c244f1afb361182c4d6eda7b5ccb2f 535 Gene3D G3DSA:1.10.8.60 362 445 1.3E-15 T 29-03-2018 CDC59_RS15195 a4c244f1afb361182c4d6eda7b5ccb2f 535 SMART SM00382 207 353 2.9E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS15195 a4c244f1afb361182c4d6eda7b5ccb2f 535 PIRSF PIRSF037354 1 531 5.2E-304 T 29-03-2018 IPR017183 Sigma54-dependent transcriptional activator, RtcR GO:0003700|GO:0006355 CDC59_RS15195 a4c244f1afb361182c4d6eda7b5ccb2f 535 Pfam PF06956 Regulator of RNA terminal phosphate cyclase 2 185 1.3E-86 T 29-03-2018 IPR009715 Regulator of RNA terminal phosphate cyclase CDC59_RS15195 a4c244f1afb361182c4d6eda7b5ccb2f 535 Pfam PF00158 Sigma-54 interaction domain 187 354 1.2E-49 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CDC59_RS02415 bdfb9b099de0789032996dd0484fc127 177 Pfam PF08281 Sigma-70, region 4 102 155 3.6E-16 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS02415 bdfb9b099de0789032996dd0484fc127 177 SUPERFAMILY SSF88946 10 89 2.28E-11 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS02415 bdfb9b099de0789032996dd0484fc127 177 SUPERFAMILY SSF88659 101 160 5.45E-16 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS02415 bdfb9b099de0789032996dd0484fc127 177 Gene3D G3DSA:1.10.1740.10 3 83 1.9E-12 T 29-03-2018 CDC59_RS02415 bdfb9b099de0789032996dd0484fc127 177 Pfam PF04542 Sigma-70 region 2 12 82 3.9E-8 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS02415 bdfb9b099de0789032996dd0484fc127 177 Gene3D G3DSA:1.10.10.10 84 165 6.1E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS02415 bdfb9b099de0789032996dd0484fc127 177 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 12 159 1.2E-16 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS07740 bbc8f637efc465efa04f86acafdd2c34 359 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 20 310 4.2E-21 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS07740 bbc8f637efc465efa04f86acafdd2c34 359 SUPERFAMILY SSF51905 20 327 5.18E-36 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS07740 bbc8f637efc465efa04f86acafdd2c34 359 Gene3D G3DSA:3.50.50.60 12 166 1.6E-19 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS07740 bbc8f637efc465efa04f86acafdd2c34 359 Gene3D G3DSA:3.40.50.720 167 355 1.5E-17 T 29-03-2018 CDC59_RS07740 bbc8f637efc465efa04f86acafdd2c34 359 Hamap MF_01685 Ferredoxin--NADP reductase. 18 347 38.419 T 29-03-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 CDC59_RS07740 bbc8f637efc465efa04f86acafdd2c34 359 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 167 191 1.3E-14 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CDC59_RS07740 bbc8f637efc465efa04f86acafdd2c34 359 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 77 87 1.3E-14 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CDC59_RS07740 bbc8f637efc465efa04f86acafdd2c34 359 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 20 42 1.3E-14 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CDC59_RS07740 bbc8f637efc465efa04f86acafdd2c34 359 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 128 136 1.3E-14 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CDC59_RS07740 bbc8f637efc465efa04f86acafdd2c34 359 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 284 306 9.9E-16 T 29-03-2018 CDC59_RS07740 bbc8f637efc465efa04f86acafdd2c34 359 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 21 40 9.9E-16 T 29-03-2018 CDC59_RS07740 bbc8f637efc465efa04f86acafdd2c34 359 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 171 189 9.9E-16 T 29-03-2018 CDC59_RS17030 c8da56b36928ca0b761c077ada5b2ceb 260 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 29-03-2018 IPR019776 Flagellar basal body rod protein, conserved site CDC59_RS17030 c8da56b36928ca0b761c077ada5b2ceb 260 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 182 260 2.3E-25 T 29-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CDC59_RS17030 c8da56b36928ca0b761c077ada5b2ceb 260 Pfam PF00460 Flagella basal body rod protein 5 35 4.1E-14 T 29-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CDC59_RS17030 c8da56b36928ca0b761c077ada5b2ceb 260 SUPERFAMILY SSF117143 92 222 5.36E-37 T 29-03-2018 CDC59_RS17030 c8da56b36928ca0b761c077ada5b2ceb 260 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 141 6.4E-53 T 29-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G CDC59_RS17030 c8da56b36928ca0b761c077ada5b2ceb 260 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 146 243 6.3E-31 T 29-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G CDC59_RS17030 c8da56b36928ca0b761c077ada5b2ceb 260 TIGRFAM TIGR02488 flgG_G_neg: flagellar basal-body rod protein FlgG 4 259 6.3E-120 T 29-03-2018 IPR012834 Flagellar basal-body rod FlgG GO:0009426|GO:0071973 CDC59_RS17030 c8da56b36928ca0b761c077ada5b2ceb 260 TIGRFAM TIGR02490 flgF: flagellar basal-body rod protein FlgF 6 241 1.6E-54 T 29-03-2018 IPR012836 Flagellar basal-body rod FlgF GO:0030694|GO:0071973 CDC59_RS22925 601c45acfa470e1c7e386771ce763091 296 Gene3D G3DSA:3.40.190.10 94 178 2.7E-10 T 29-03-2018 CDC59_RS22925 601c45acfa470e1c7e386771ce763091 296 SUPERFAMILY SSF46785 4 82 7.93E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS22925 601c45acfa470e1c7e386771ce763091 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 67 1.0E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS22925 601c45acfa470e1c7e386771ce763091 296 Gene3D G3DSA:1.10.10.10 4 90 1.0E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS22925 601c45acfa470e1c7e386771ce763091 296 Gene3D G3DSA:3.40.190.10 179 264 1.8E-19 T 29-03-2018 CDC59_RS22925 601c45acfa470e1c7e386771ce763091 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 2.0E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS22925 601c45acfa470e1c7e386771ce763091 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 2.0E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS22925 601c45acfa470e1c7e386771ce763091 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 2.0E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS22925 601c45acfa470e1c7e386771ce763091 296 Pfam PF03466 LysR substrate binding domain 96 293 1.1E-27 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS22925 601c45acfa470e1c7e386771ce763091 296 SUPERFAMILY SSF53850 97 296 1.72E-29 T 29-03-2018 CDC59_RS16220 e708a8ee99e0fcad3488d9bc1b23bb27 437 Pfam PF00083 Sugar (and other) transporter 26 222 7.9E-21 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CDC59_RS16220 e708a8ee99e0fcad3488d9bc1b23bb27 437 Pfam PF07690 Major Facilitator Superfamily 273 431 3.8E-10 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDC59_RS16220 e708a8ee99e0fcad3488d9bc1b23bb27 437 Gene3D G3DSA:1.20.1250.20 16 234 1.7E-20 T 29-03-2018 CDC59_RS16220 e708a8ee99e0fcad3488d9bc1b23bb27 437 TIGRFAM TIGR00883 2A0106: MFS transporter, metabolite:H+ symporter (MHS) family protein 31 416 4.0E-134 T 29-03-2018 IPR004736 Citrate-proton symport GO:0005215|GO:0006810|GO:0016021 CDC59_RS16220 e708a8ee99e0fcad3488d9bc1b23bb27 437 Gene3D G3DSA:1.20.1250.20 242 436 2.2E-22 T 29-03-2018 CDC59_RS16220 e708a8ee99e0fcad3488d9bc1b23bb27 437 SUPERFAMILY SSF103473 19 428 1.57E-61 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS16220 e708a8ee99e0fcad3488d9bc1b23bb27 437 ProSitePatterns PS00217 Sugar transport proteins signature 2. 134 159 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CDC59_RS22950 c433380acd288720ecb30d0615cf94fc 483 SUPERFAMILY SSF56954 6 475 1.31E-105 T 29-03-2018 CDC59_RS22950 c433380acd288720ecb30d0615cf94fc 483 Pfam PF02321 Outer membrane efflux protein 289 452 2.5E-25 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CDC59_RS22950 c433380acd288720ecb30d0615cf94fc 483 Pfam PF02321 Outer membrane efflux protein 68 262 1.8E-16 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CDC59_RS22950 c433380acd288720ecb30d0615cf94fc 483 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 15 470 6.0E-120 T 29-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 CDC59_RS22950 c433380acd288720ecb30d0615cf94fc 483 Gene3D G3DSA:1.20.1600.10 22 477 2.5E-99 T 29-03-2018 CDC59_RS05315 61d7a757d264b67fb843baef9ec63e3e 159 Gene3D G3DSA:3.30.2000.10 4 140 1.5E-21 T 29-03-2018 CDC59_RS11305 a715e68b2cd1d915d7d64c35e6fa8562 316 SUPERFAMILY SSF55961 174 315 1.16E-32 T 29-03-2018 CDC59_RS11305 a715e68b2cd1d915d7d64c35e6fa8562 316 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 183 314 1.9E-24 T 29-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CDC59_RS11305 a715e68b2cd1d915d7d64c35e6fa8562 316 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 24 155 6.9E-28 T 29-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CDC59_RS11305 a715e68b2cd1d915d7d64c35e6fa8562 316 SUPERFAMILY SSF55961 13 159 2.03E-39 T 29-03-2018 CDC59_RS11305 a715e68b2cd1d915d7d64c35e6fa8562 316 Gene3D G3DSA:3.30.530.20 170 316 4.9E-23 T 29-03-2018 IPR023393 START-like domain CDC59_RS11305 a715e68b2cd1d915d7d64c35e6fa8562 316 Gene3D G3DSA:3.30.530.20 5 169 1.5E-30 T 29-03-2018 IPR023393 START-like domain CDC59_RS07950 dab21dd9902963a3d1f3761af68139ce 465 Gene3D G3DSA:1.10.1160.10 238 321 2.3E-33 T 29-03-2018 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 CDC59_RS07950 dab21dd9902963a3d1f3761af68139ce 465 PRINTS PR00987 Glutamyl-tRNA synthetase signature 22 33 2.1E-24 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CDC59_RS07950 dab21dd9902963a3d1f3761af68139ce 465 PRINTS PR00987 Glutamyl-tRNA synthetase signature 185 195 2.1E-24 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CDC59_RS07950 dab21dd9902963a3d1f3761af68139ce 465 PRINTS PR00987 Glutamyl-tRNA synthetase signature 37 50 2.1E-24 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CDC59_RS07950 dab21dd9902963a3d1f3761af68139ce 465 PRINTS PR00987 Glutamyl-tRNA synthetase signature 201 209 2.1E-24 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CDC59_RS07950 dab21dd9902963a3d1f3761af68139ce 465 PRINTS PR00987 Glutamyl-tRNA synthetase signature 8 20 2.1E-24 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CDC59_RS07950 dab21dd9902963a3d1f3761af68139ce 465 SUPERFAMILY SSF48163 305 463 4.71E-40 T 29-03-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CDC59_RS07950 dab21dd9902963a3d1f3761af68139ce 465 Gene3D G3DSA:3.40.50.620 1 126 7.9E-39 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDC59_RS07950 dab21dd9902963a3d1f3761af68139ce 465 SUPERFAMILY SSF52374 5 302 1.69E-109 T 29-03-2018 CDC59_RS07950 dab21dd9902963a3d1f3761af68139ce 465 Gene3D G3DSA:1.10.10.350 375 465 1.9E-17 T 29-03-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CDC59_RS07950 dab21dd9902963a3d1f3761af68139ce 465 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 5 311 1.7E-99 T 29-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 CDC59_RS07950 dab21dd9902963a3d1f3761af68139ce 465 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 11 22 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDC59_RS07950 dab21dd9902963a3d1f3761af68139ce 465 Gene3D G3DSA:1.10.8.70 323 367 2.7E-9 T 29-03-2018 IPR020752 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 1 GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 CDC59_RS07950 dab21dd9902963a3d1f3761af68139ce 465 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 5 464 8.3E-166 T 29-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CDC59_RS07950 dab21dd9902963a3d1f3761af68139ce 465 Gene3D G3DSA:3.40.50.620 127 237 9.1E-27 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDC59_RS07950 dab21dd9902963a3d1f3761af68139ce 465 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 4 465 30.102 T 29-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CDC59_RS03420 7486e4f90804bd720753153887368fb9 456 Gene3D G3DSA:3.30.1490.20 124 210 2.4E-21 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CDC59_RS03420 7486e4f90804bd720753153887368fb9 456 SUPERFAMILY SSF51246 331 444 8.37E-43 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CDC59_RS03420 7486e4f90804bd720753153887368fb9 456 Pfam PF02785 Biotin carboxylase C-terminal domain 336 441 5.9E-38 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CDC59_RS03420 7486e4f90804bd720753153887368fb9 456 SUPERFAMILY SSF56059 83 348 1.71E-71 T 29-03-2018 CDC59_RS03420 7486e4f90804bd720753153887368fb9 456 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 3.0E-45 T 29-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CDC59_RS03420 7486e4f90804bd720753153887368fb9 456 Gene3D G3DSA:3.40.50.20 1 123 4.0E-53 T 29-03-2018 CDC59_RS03420 7486e4f90804bd720753153887368fb9 456 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 446 6.3E-224 T 29-03-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 CDC59_RS03420 7486e4f90804bd720753153887368fb9 456 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 322 8.1E-81 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CDC59_RS03420 7486e4f90804bd720753153887368fb9 456 SMART SM00878 336 441 2.9E-64 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CDC59_RS03420 7486e4f90804bd720753153887368fb9 456 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 154 168 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CDC59_RS03420 7486e4f90804bd720753153887368fb9 456 Gene3D G3DSA:3.30.470.20 211 444 2.3E-96 T 29-03-2018 CDC59_RS03420 7486e4f90804bd720753153887368fb9 456 SUPERFAMILY SSF52440 1 113 9.35E-49 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CDC59_RS03420 7486e4f90804bd720753153887368fb9 456 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CDC59_RS10975 faaabe41ed3137b629c3407535e7f3b0 378 Pfam PF00117 Glutamine amidotransferase class-I 196 371 5.4E-47 T 29-03-2018 IPR017926 Glutamine amidotransferase CDC59_RS10975 faaabe41ed3137b629c3407535e7f3b0 378 Gene3D G3DSA:3.40.50.880 154 378 3.7E-66 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CDC59_RS10975 faaabe41ed3137b629c3407535e7f3b0 378 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 8 374 3.4E-145 T 29-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDC59_RS10975 faaabe41ed3137b629c3407535e7f3b0 378 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 6 377 48.052 T 29-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDC59_RS10975 faaabe41ed3137b629c3407535e7f3b0 378 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 8 135 2.3E-51 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDC59_RS10975 faaabe41ed3137b629c3407535e7f3b0 378 SUPERFAMILY SSF52317 156 377 2.14E-64 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CDC59_RS10975 faaabe41ed3137b629c3407535e7f3b0 378 SMART SM01097 6 136 4.4E-87 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDC59_RS10975 faaabe41ed3137b629c3407535e7f3b0 378 Gene3D G3DSA:3.50.30.20 5 153 2.5E-59 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDC59_RS10975 faaabe41ed3137b629c3407535e7f3b0 378 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 263 279 1.4E-38 T 29-03-2018 CDC59_RS10975 faaabe41ed3137b629c3407535e7f3b0 378 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 232 246 1.4E-38 T 29-03-2018 CDC59_RS10975 faaabe41ed3137b629c3407535e7f3b0 378 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 193 207 1.4E-38 T 29-03-2018 CDC59_RS10975 faaabe41ed3137b629c3407535e7f3b0 378 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 305 316 1.4E-38 T 29-03-2018 CDC59_RS10975 faaabe41ed3137b629c3407535e7f3b0 378 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 280 297 1.4E-38 T 29-03-2018 CDC59_RS10975 faaabe41ed3137b629c3407535e7f3b0 378 PRINTS PR00096 Glutamine amidotransferase superfamily signature 235 244 8.1E-10 T 29-03-2018 CDC59_RS10975 faaabe41ed3137b629c3407535e7f3b0 378 PRINTS PR00096 Glutamine amidotransferase superfamily signature 348 361 8.1E-10 T 29-03-2018 CDC59_RS10975 faaabe41ed3137b629c3407535e7f3b0 378 PRINTS PR00096 Glutamine amidotransferase superfamily signature 263 274 8.1E-10 T 29-03-2018 CDC59_RS10975 faaabe41ed3137b629c3407535e7f3b0 378 SUPERFAMILY SSF52021 7 152 4.58E-56 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDC59_RS03535 edb0b66685f5bc2ad622b84ec360beed 249 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 4 247 2.3E-52 T 29-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CDC59_RS03535 edb0b66685f5bc2ad622b84ec360beed 249 Pfam PF04452 RNA methyltransferase 18 243 1.5E-67 T 29-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CDC59_RS03535 edb0b66685f5bc2ad622b84ec360beed 249 Gene3D G3DSA:2.40.240.20 1 72 7.2E-20 T 29-03-2018 CDC59_RS03535 edb0b66685f5bc2ad622b84ec360beed 249 PIRSF PIRSF015601 3 249 1.2E-53 T 29-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CDC59_RS03535 edb0b66685f5bc2ad622b84ec360beed 249 Gene3D G3DSA:3.40.1280.10 73 249 1.2E-56 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CDC59_RS03535 edb0b66685f5bc2ad622b84ec360beed 249 SUPERFAMILY SSF88697 3 69 1.01E-14 T 29-03-2018 IPR015947 PUA-like domain CDC59_RS03535 edb0b66685f5bc2ad622b84ec360beed 249 SUPERFAMILY SSF75217 73 247 6.73E-48 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases CDC59_RS13050 f9fc2f08c64b6cab83cc36b7ea598cc4 547 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 29-03-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CDC59_RS13050 f9fc2f08c64b6cab83cc36b7ea598cc4 547 Gene3D G3DSA:1.10.560.10 1 184 1.7E-43 T 29-03-2018 IPR027413 GroEL-like equatorial domain CDC59_RS13050 f9fc2f08c64b6cab83cc36b7ea598cc4 547 Gene3D G3DSA:3.50.7.10 185 373 1.6E-98 T 29-03-2018 IPR027409 GroEL-like apical domain CDC59_RS13050 f9fc2f08c64b6cab83cc36b7ea598cc4 547 SUPERFAMILY SSF48592 406 521 2.75E-78 T 29-03-2018 CDC59_RS13050 f9fc2f08c64b6cab83cc36b7ea598cc4 547 SUPERFAMILY SSF48592 7 134 2.75E-78 T 29-03-2018 CDC59_RS13050 f9fc2f08c64b6cab83cc36b7ea598cc4 547 Pfam PF00118 TCP-1/cpn60 chaperonin family 23 522 4.1E-101 T 29-03-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 CDC59_RS13050 f9fc2f08c64b6cab83cc36b7ea598cc4 547 PRINTS PR00298 60kDa chaperonin signature 268 291 1.6E-74 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CDC59_RS13050 f9fc2f08c64b6cab83cc36b7ea598cc4 547 PRINTS PR00298 60kDa chaperonin signature 350 375 1.6E-74 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CDC59_RS13050 f9fc2f08c64b6cab83cc36b7ea598cc4 547 PRINTS PR00298 60kDa chaperonin signature 398 419 1.6E-74 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CDC59_RS13050 f9fc2f08c64b6cab83cc36b7ea598cc4 547 PRINTS PR00298 60kDa chaperonin signature 83 110 1.6E-74 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CDC59_RS13050 f9fc2f08c64b6cab83cc36b7ea598cc4 547 PRINTS PR00298 60kDa chaperonin signature 27 53 1.6E-74 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CDC59_RS13050 f9fc2f08c64b6cab83cc36b7ea598cc4 547 SUPERFAMILY SSF54849 137 203 4.35E-24 T 29-03-2018 CDC59_RS13050 f9fc2f08c64b6cab83cc36b7ea598cc4 547 Hamap MF_00600 60 kDa chaperonin [groL]. 2 546 41.809 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CDC59_RS13050 f9fc2f08c64b6cab83cc36b7ea598cc4 547 Gene3D G3DSA:1.10.560.10 374 516 1.4E-25 T 29-03-2018 IPR027413 GroEL-like equatorial domain CDC59_RS13050 f9fc2f08c64b6cab83cc36b7ea598cc4 547 SUPERFAMILY SSF52029 185 376 4.19E-84 T 29-03-2018 IPR027409 GroEL-like apical domain CDC59_RS13050 f9fc2f08c64b6cab83cc36b7ea598cc4 547 TIGRFAM TIGR02348 GroEL: chaperonin GroL 3 526 1.5E-255 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CDC59_RS05135 ee7c9c1cec8123229768523e724c6b04 141 SUPERFAMILY SSF52402 3 141 6.45E-28 T 29-03-2018 CDC59_RS05135 ee7c9c1cec8123229768523e724c6b04 141 Gene3D G3DSA:3.40.50.620 2 141 6.7E-29 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDC59_RS05135 ee7c9c1cec8123229768523e724c6b04 141 PRINTS PR01438 Universal stress protein signature 119 141 2.9E-10 T 29-03-2018 IPR006015 Universal stress protein A CDC59_RS05135 ee7c9c1cec8123229768523e724c6b04 141 PRINTS PR01438 Universal stress protein signature 101 113 2.9E-10 T 29-03-2018 IPR006015 Universal stress protein A CDC59_RS05135 ee7c9c1cec8123229768523e724c6b04 141 PRINTS PR01438 Universal stress protein signature 1 18 2.9E-10 T 29-03-2018 IPR006015 Universal stress protein A CDC59_RS05135 ee7c9c1cec8123229768523e724c6b04 141 Pfam PF00582 Universal stress protein family 3 141 1.8E-23 T 29-03-2018 IPR006016 UspA GO:0006950 CDC59_RS05080 77997e9a70b7a3b4d9a1c4538f34d5ff 467 Gene3D G3DSA:3.90.226.10 30 226 9.6E-20 T 29-03-2018 CDC59_RS05080 77997e9a70b7a3b4d9a1c4538f34d5ff 467 SUPERFAMILY SSF52096 165 223 3.8E-25 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CDC59_RS05080 77997e9a70b7a3b4d9a1c4538f34d5ff 467 SUPERFAMILY SSF52096 30 137 3.8E-25 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CDC59_RS05080 77997e9a70b7a3b4d9a1c4538f34d5ff 467 Gene3D G3DSA:2.40.50.140 394 467 9.7E-22 T 29-03-2018 CDC59_RS05080 77997e9a70b7a3b4d9a1c4538f34d5ff 467 SUPERFAMILY SSF141322 395 466 9.42E-10 T 29-03-2018 CDC59_RS05080 77997e9a70b7a3b4d9a1c4538f34d5ff 467 Pfam PF01957 NfeD-like C-terminal, partner-binding 324 466 6.9E-38 T 29-03-2018 IPR002810 NfeD-like, C-terminal domain CDC59_RS04680 480378a2c6fb1ac367629316c44d1faf 203 Pfam PF12019 Type II transport protein GspH 51 179 2.6E-12 T 29-03-2018 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 CDC59_RS04680 480378a2c6fb1ac367629316c44d1faf 203 Gene3D G3DSA:3.30.700.10 16 199 3.9E-18 T 29-03-2018 CDC59_RS04680 480378a2c6fb1ac367629316c44d1faf 203 SUPERFAMILY SSF54523 16 111 1.88E-17 T 29-03-2018 CDC59_RS04680 480378a2c6fb1ac367629316c44d1faf 203 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 14 35 1.1E-7 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS04680 480378a2c6fb1ac367629316c44d1faf 203 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 14 34 - T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS04680 480378a2c6fb1ac367629316c44d1faf 203 Pfam PF07963 Prokaryotic N-terminal methylation motif 13 35 1.1E-7 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS01530 26dcce5c3f5d41b96fc1eba3601c64c0 113 Pfam PF01381 Helix-turn-helix 28 82 1.6E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDC59_RS01530 26dcce5c3f5d41b96fc1eba3601c64c0 113 Gene3D G3DSA:1.10.260.40 13 90 1.5E-19 T 29-03-2018 CDC59_RS01530 26dcce5c3f5d41b96fc1eba3601c64c0 113 SUPERFAMILY SSF47413 20 86 3.66E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDC59_RS01530 26dcce5c3f5d41b96fc1eba3601c64c0 113 SMART SM00530 27 82 5.1E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDC59_RS04460 2210f13e03b7664f966ec97b9b034652 283 Hamap MF_00199 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical [apaH]. 6 271 44.059 T 29-03-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 CDC59_RS04460 2210f13e03b7664f966ec97b9b034652 283 Pfam PF00149 Calcineurin-like phosphoesterase 11 149 3.3E-7 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CDC59_RS04460 2210f13e03b7664f966ec97b9b034652 283 SUPERFAMILY SSF56300 8 257 1.65E-48 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CDC59_RS04460 2210f13e03b7664f966ec97b9b034652 283 PIRSF PIRSF000903 6 279 7.2E-99 T 29-03-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 CDC59_RS04460 2210f13e03b7664f966ec97b9b034652 283 Gene3D G3DSA:3.60.21.10 5 283 2.2E-39 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CDC59_RS04460 2210f13e03b7664f966ec97b9b034652 283 TIGRFAM TIGR00668 apaH: bis(5'-nucleosyl)-tetraphosphatase (symmetrical) 10 257 1.7E-67 T 29-03-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 CDC59_RS08845 0c3c1f32beea9496ef212fed0437791d 71 SUPERFAMILY SSF50331 6 69 4.37E-17 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CDC59_RS08845 0c3c1f32beea9496ef212fed0437791d 71 Gene3D G3DSA:2.40.50.100 5 70 3.1E-17 T 29-03-2018 CDC59_RS08845 0c3c1f32beea9496ef212fed0437791d 71 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 6 69 2.5E-17 T 29-03-2018 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 CDC59_RS08845 0c3c1f32beea9496ef212fed0437791d 71 Pfam PF03459 TOBE domain 8 67 4.6E-16 T 29-03-2018 IPR005116 Transport-associated OB, type 1 CDC59_RS03020 99aa722697ba5d45d0743e4603478184 354 Pfam PF00005 ABC transporter 64 214 2.0E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS03020 99aa722697ba5d45d0743e4603478184 354 SMART SM00382 72 264 5.8E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS03020 99aa722697ba5d45d0743e4603478184 354 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 264 350 1.3E-26 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CDC59_RS03020 99aa722697ba5d45d0743e4603478184 354 SUPERFAMILY SSF52540 55 286 1.33E-66 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS03020 99aa722697ba5d45d0743e4603478184 354 Gene3D G3DSA:3.40.50.300 24 354 9.0E-77 T 29-03-2018 CDC59_RS03020 99aa722697ba5d45d0743e4603478184 354 ProSitePatterns PS00211 ABC transporters family signature. 187 201 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS03020 99aa722697ba5d45d0743e4603478184 354 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 266 330 1.2E-17 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CDC59_RS10535 44713b05dceb24356de675502f881959 154 SUPERFAMILY SSF46785 8 144 2.58E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS10535 44713b05dceb24356de675502f881959 154 Pfam PF01047 MarR family 34 90 3.5E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS10535 44713b05dceb24356de675502f881959 154 Gene3D G3DSA:1.10.10.10 2 149 1.7E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS10535 44713b05dceb24356de675502f881959 154 TIGRFAM TIGR02337 HpaR: homoprotocatechuate degradation operon regulator, HpaR 9 138 6.7E-54 T 29-03-2018 IPR012712 Homoprotocatechuate degradation transcriptional regulator HpaR GO:0003677|GO:0010124|GO:0045892 CDC59_RS10535 44713b05dceb24356de675502f881959 154 SMART SM00347 27 127 9.1E-20 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS22230 6d6fe47c2333ebe8c982bbc544f1afe3 155 Gene3D G3DSA:3.30.700.10 16 155 7.0E-21 T 29-03-2018 CDC59_RS22230 6d6fe47c2333ebe8c982bbc544f1afe3 155 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 14 36 9.2E-9 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS22230 6d6fe47c2333ebe8c982bbc544f1afe3 155 Pfam PF07963 Prokaryotic N-terminal methylation motif 11 36 1.3E-9 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS22230 6d6fe47c2333ebe8c982bbc544f1afe3 155 Pfam PF16732 Type IV minor pilin ComP, DNA uptake sequence receptor 37 137 3.5E-17 T 29-03-2018 IPR031982 Type IV minor pilin ComP CDC59_RS22230 6d6fe47c2333ebe8c982bbc544f1afe3 155 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 14 34 - T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS22230 6d6fe47c2333ebe8c982bbc544f1afe3 155 SUPERFAMILY SSF54523 16 146 8.63E-22 T 29-03-2018 CDC59_RS11160 b609450f024da59b1c96edba4b90f43b 324 SUPERFAMILY SSF53850 88 295 1.76E-32 T 29-03-2018 CDC59_RS11160 b609450f024da59b1c96edba4b90f43b 324 Gene3D G3DSA:3.40.190.10 92 174 7.2E-16 T 29-03-2018 CDC59_RS11160 b609450f024da59b1c96edba4b90f43b 324 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 7.1E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS11160 b609450f024da59b1c96edba4b90f43b 324 SUPERFAMILY SSF46785 1 84 1.77E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS11160 b609450f024da59b1c96edba4b90f43b 324 Pfam PF03466 LysR substrate binding domain 87 289 7.1E-32 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS11160 b609450f024da59b1c96edba4b90f43b 324 Gene3D G3DSA:1.10.10.10 1 91 8.1E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS11160 b609450f024da59b1c96edba4b90f43b 324 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.8E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS11160 b609450f024da59b1c96edba4b90f43b 324 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.8E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS11160 b609450f024da59b1c96edba4b90f43b 324 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.8E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS11160 b609450f024da59b1c96edba4b90f43b 324 Gene3D G3DSA:3.40.190.10 175 262 5.5E-19 T 29-03-2018 CDC59_RS13535 ecf96e4a0bed1f77368ee318e11a2818 307 Pfam PF13452 N-terminal half of MaoC dehydratase 74 156 7.3E-5 T 29-03-2018 CDC59_RS13535 ecf96e4a0bed1f77368ee318e11a2818 307 SUPERFAMILY SSF54637 188 277 2.51E-17 T 29-03-2018 IPR029069 HotDog domain CDC59_RS13535 ecf96e4a0bed1f77368ee318e11a2818 307 SUPERFAMILY SSF54637 56 166 4.26E-12 T 29-03-2018 IPR029069 HotDog domain CDC59_RS13535 ecf96e4a0bed1f77368ee318e11a2818 307 Gene3D G3DSA:3.10.129.10 44 177 2.1E-21 T 29-03-2018 CDC59_RS13535 ecf96e4a0bed1f77368ee318e11a2818 307 PRINTS PR01483 Fatty acid synthase signature 215 236 1.6E-7 T 29-03-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 CDC59_RS13535 ecf96e4a0bed1f77368ee318e11a2818 307 PRINTS PR01483 Fatty acid synthase signature 193 215 1.6E-7 T 29-03-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 CDC59_RS13535 ecf96e4a0bed1f77368ee318e11a2818 307 Gene3D G3DSA:3.10.129.10 179 271 3.5E-17 T 29-03-2018 CDC59_RS13535 ecf96e4a0bed1f77368ee318e11a2818 307 Pfam PF01575 MaoC like domain 197 239 9.1E-13 T 29-03-2018 IPR002539 MaoC-like domain CDC59_RS07505 0ed34fc9c8234ae54972e9a9330c7c6b 348 TIGRFAM TIGR02272 gentisate_1_2: gentisate 1,2-dioxygenase 9 347 1.6E-182 T 29-03-2018 IPR011960 Gentisate 1,2-dioxygenase CDC59_RS07505 0ed34fc9c8234ae54972e9a9330c7c6b 348 Pfam PF07883 Cupin domain 93 164 9.0E-23 T 29-03-2018 IPR013096 Cupin 2, conserved barrel CDC59_RS07505 0ed34fc9c8234ae54972e9a9330c7c6b 348 Gene3D G3DSA:2.60.120.10 43 348 2.0E-34 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CDC59_RS07505 0ed34fc9c8234ae54972e9a9330c7c6b 348 SUPERFAMILY SSF51182 12 346 7.19E-111 T 29-03-2018 IPR011051 RmlC-like cupin domain CDC59_RS15510 c25844ebdf5efbc90ce189f840282abd 202 Pfam PF13417 Glutathione S-transferase, N-terminal domain 3 75 4.7E-21 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CDC59_RS15510 c25844ebdf5efbc90ce189f840282abd 202 Gene3D G3DSA:3.40.30.10 1 85 2.1E-15 T 29-03-2018 CDC59_RS15510 c25844ebdf5efbc90ce189f840282abd 202 SUPERFAMILY SSF47616 74 199 1.56E-5 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like CDC59_RS15510 c25844ebdf5efbc90ce189f840282abd 202 Gene3D G3DSA:1.20.1050.10 86 200 6.8E-9 T 29-03-2018 CDC59_RS15510 c25844ebdf5efbc90ce189f840282abd 202 SUPERFAMILY SSF52833 1 83 5.04E-16 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS12145 12dcc70e61e6d48f43480cc1619dcb52 695 Pfam PF04375 HemX, putative uroporphyrinogen-III C-methyltransferase 357 688 4.8E-41 T 29-03-2018 IPR007470 Putative uroporphyrinogen-III C-methyltransferase HemX CDC59_RS12145 12dcc70e61e6d48f43480cc1619dcb52 695 Gene3D G3DSA:3.40.50.10090 21 152 7.4E-29 T 29-03-2018 CDC59_RS12145 12dcc70e61e6d48f43480cc1619dcb52 695 Gene3D G3DSA:3.40.50.10090 155 279 2.6E-17 T 29-03-2018 CDC59_RS12145 12dcc70e61e6d48f43480cc1619dcb52 695 SUPERFAMILY SSF69618 22 278 2.75E-49 T 29-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CDC59_RS12145 12dcc70e61e6d48f43480cc1619dcb52 695 Pfam PF02602 Uroporphyrinogen-III synthase HemD 36 263 1.4E-35 T 29-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CDC59_RS14330 aec3323ec5a9757d45f57802489ad7a5 168 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 3 57 1.5E-17 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CDC59_RS14330 aec3323ec5a9757d45f57802489ad7a5 168 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 20 41 1.9E-47 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CDC59_RS14330 aec3323ec5a9757d45f57802489ad7a5 168 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 85 101 1.9E-47 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CDC59_RS14330 aec3323ec5a9757d45f57802489ad7a5 168 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 49 73 1.9E-47 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CDC59_RS14330 aec3323ec5a9757d45f57802489ad7a5 168 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 112 134 1.9E-47 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CDC59_RS14330 aec3323ec5a9757d45f57802489ad7a5 168 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 2 20 1.9E-47 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CDC59_RS14330 aec3323ec5a9757d45f57802489ad7a5 168 Pfam PF01467 Cytidylyltransferase-like 5 133 3.4E-17 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CDC59_RS14330 aec3323ec5a9757d45f57802489ad7a5 168 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 2 158 35.44 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CDC59_RS14330 aec3323ec5a9757d45f57802489ad7a5 168 Gene3D G3DSA:3.40.50.620 1 158 1.5E-37 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDC59_RS14330 aec3323ec5a9757d45f57802489ad7a5 168 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 3 156 7.2E-56 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CDC59_RS14330 aec3323ec5a9757d45f57802489ad7a5 168 SUPERFAMILY SSF52374 3 156 2.56E-45 T 29-03-2018 CDC59_RS06375 21f545c5f82db8c95529907b106cc9bd 215 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 4 200 8.8E-72 T 29-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D CDC59_RS06375 21f545c5f82db8c95529907b106cc9bd 215 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 8 209 1.1E-77 T 29-03-2018 IPR010016 KipI family CDC59_RS06375 21f545c5f82db8c95529907b106cc9bd 215 SMART SM00796 3 200 4.1E-103 T 29-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D CDC59_RS06375 21f545c5f82db8c95529907b106cc9bd 215 SUPERFAMILY SSF50891 86 210 3.79E-46 T 29-03-2018 IPR029000 Cyclophilin-like domain CDC59_RS06375 21f545c5f82db8c95529907b106cc9bd 215 Gene3D G3DSA:3.30.1360.40 3 82 7.3E-12 T 29-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CDC59_RS06375 21f545c5f82db8c95529907b106cc9bd 215 Gene3D G3DSA:2.40.100.10 84 214 5.1E-51 T 29-03-2018 IPR029000 Cyclophilin-like domain CDC59_RS06375 21f545c5f82db8c95529907b106cc9bd 215 SUPERFAMILY SSF160467 4 88 1.96E-9 T 29-03-2018 CDC59_RS00780 555a717715eed95e2bc60a0fcee38687 297 Gene3D G3DSA:3.40.190.10 176 263 4.0E-26 T 29-03-2018 CDC59_RS00780 555a717715eed95e2bc60a0fcee38687 297 Pfam PF03466 LysR substrate binding domain 88 292 7.7E-49 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS00780 555a717715eed95e2bc60a0fcee38687 297 SUPERFAMILY SSF46785 4 87 2.78E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS00780 555a717715eed95e2bc60a0fcee38687 297 Gene3D G3DSA:3.40.190.10 88 175 5.1E-20 T 29-03-2018 CDC59_RS00780 555a717715eed95e2bc60a0fcee38687 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 2.1E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS00780 555a717715eed95e2bc60a0fcee38687 297 SUPERFAMILY SSF53850 89 295 3.04E-51 T 29-03-2018 CDC59_RS00780 555a717715eed95e2bc60a0fcee38687 297 Gene3D G3DSA:1.10.10.10 3 84 6.6E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS07280 821baf6118411cb31166ef968395f908 198 TIGRFAM TIGR00172 maf: septum formation protein Maf 9 190 3.0E-46 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 CDC59_RS07280 821baf6118411cb31166ef968395f908 198 Gene3D G3DSA:3.90.950.10 7 198 8.8E-56 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CDC59_RS07280 821baf6118411cb31166ef968395f908 198 Hamap MF_00528 Septum formation protein Maf [maf]. 8 196 29.856 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 CDC59_RS07280 821baf6118411cb31166ef968395f908 198 PIRSF PIRSF006305 2 196 1.1E-42 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 CDC59_RS07280 821baf6118411cb31166ef968395f908 198 SUPERFAMILY SSF52972 7 191 5.95E-57 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CDC59_RS07280 821baf6118411cb31166ef968395f908 198 Pfam PF02545 Maf-like protein 9 191 2.7E-43 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 CDC59_RS02925 581afe7f6890388ddade2c24f63b388b 246 Pfam PF13419 Haloacid dehalogenase-like hydrolase 13 198 2.4E-33 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS02925 581afe7f6890388ddade2c24f63b388b 246 SUPERFAMILY SSF56784 9 227 2.4E-57 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS02925 581afe7f6890388ddade2c24f63b388b 246 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 115 192 2.3E-7 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDC59_RS02925 581afe7f6890388ddade2c24f63b388b 246 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 187 200 8.6E-8 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDC59_RS02925 581afe7f6890388ddade2c24f63b388b 246 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 111 124 8.6E-8 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDC59_RS02925 581afe7f6890388ddade2c24f63b388b 246 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 160 180 8.6E-8 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDC59_RS02925 581afe7f6890388ddade2c24f63b388b 246 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 10 21 8.6E-8 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDC59_RS02925 581afe7f6890388ddade2c24f63b388b 246 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 142 158 8.6E-8 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDC59_RS02925 581afe7f6890388ddade2c24f63b388b 246 TIGRFAM TIGR01449 PGP_bact: phosphoglycolate phosphatase, bacterial 13 224 3.8E-62 T 29-03-2018 IPR006346 2-phosphoglycolate phosphatase, prokaryotic GO:0008967|GO:0046295 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 CDC59_RS02925 581afe7f6890388ddade2c24f63b388b 246 Gene3D G3DSA:1.10.150.240 26 86 3.1E-17 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CDC59_RS02925 581afe7f6890388ddade2c24f63b388b 246 Gene3D G3DSA:3.40.50.1000 87 235 1.9E-35 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS02925 581afe7f6890388ddade2c24f63b388b 246 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 86 197 5.4E-13 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDC59_RS18040 6fc96ebcc062b50c46bc1b48584c61e0 581 Gene3D G3DSA:3.20.20.370 268 580 1.3E-7 T 29-03-2018 CDC59_RS18040 6fc96ebcc062b50c46bc1b48584c61e0 581 Pfam PF10096 Uncharacterized protein conserved in bacteria (DUF2334) 270 555 1.1E-48 T 29-03-2018 IPR018763 Protein of unknown function DUF2334 CDC59_RS17675 df270315d0db88a59500026d7201d50a 476 PRINTS PR00344 Bacterial sensor protein C-terminal signature 419 437 5.4E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS17675 df270315d0db88a59500026d7201d50a 476 PRINTS PR00344 Bacterial sensor protein C-terminal signature 443 456 5.4E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS17675 df270315d0db88a59500026d7201d50a 476 PRINTS PR00344 Bacterial sensor protein C-terminal signature 388 402 5.4E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS17675 df270315d0db88a59500026d7201d50a 476 PRINTS PR00344 Bacterial sensor protein C-terminal signature 406 416 5.4E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS17675 df270315d0db88a59500026d7201d50a 476 Pfam PF16927 N-terminal 7TM region of histidine kinase 9 216 2.9E-11 T 29-03-2018 IPR031621 Histidine kinase, N-terminal 7TM region CDC59_RS17675 df270315d0db88a59500026d7201d50a 476 Gene3D G3DSA:3.30.565.10 316 465 1.5E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS17675 df270315d0db88a59500026d7201d50a 476 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 352 457 4.1E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS17675 df270315d0db88a59500026d7201d50a 476 Gene3D G3DSA:1.10.287.130 206 315 2.4E-4 T 29-03-2018 CDC59_RS17675 df270315d0db88a59500026d7201d50a 476 SMART SM00387 349 459 2.2E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS17675 df270315d0db88a59500026d7201d50a 476 SUPERFAMILY SSF55874 306 457 5.37E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS13470 38d1fa0fa3b22b7110b443142d66fc44 567 ProSitePatterns PS00217 Sugar transport proteins signature 2. 137 162 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CDC59_RS13470 38d1fa0fa3b22b7110b443142d66fc44 567 Pfam PF00083 Sugar (and other) transporter 29 337 3.5E-26 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CDC59_RS13470 38d1fa0fa3b22b7110b443142d66fc44 567 Pfam PF00083 Sugar (and other) transporter 458 564 2.5E-6 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CDC59_RS13470 38d1fa0fa3b22b7110b443142d66fc44 567 SUPERFAMILY SSF103473 468 563 6.8E-62 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS13470 38d1fa0fa3b22b7110b443142d66fc44 567 SUPERFAMILY SSF103473 20 344 6.8E-62 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS13470 38d1fa0fa3b22b7110b443142d66fc44 567 Gene3D G3DSA:1.20.1250.20 234 564 8.4E-34 T 29-03-2018 CDC59_RS13470 38d1fa0fa3b22b7110b443142d66fc44 567 Gene3D G3DSA:1.20.1250.20 18 233 1.4E-26 T 29-03-2018 CDC59_RS12285 4e8683ee3415f8f3bf03a3d45ee60067 589 Gene3D G3DSA:2.40.160.50 240 589 2.4E-46 T 29-03-2018 CDC59_RS12285 4e8683ee3415f8f3bf03a3d45ee60067 589 Gene3D G3DSA:3.10.20.310 116 205 9.3E-13 T 29-03-2018 CDC59_RS12285 4e8683ee3415f8f3bf03a3d45ee60067 589 Pfam PF01103 Surface antigen 357 577 4.5E-32 T 29-03-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 CDC59_RS13720 fb2e27806361229e547f471477a30141 524 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 4 524 8.8E-224 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CDC59_RS13720 fb2e27806361229e547f471477a30141 524 Gene3D G3DSA:3.40.140.20 229 370 2.0E-49 T 29-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CDC59_RS13720 fb2e27806361229e547f471477a30141 524 Pfam PF02142 MGS-like domain 14 129 1.3E-30 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CDC59_RS13720 fb2e27806361229e547f471477a30141 524 Gene3D G3DSA:3.40.50.1380 1 193 7.6E-77 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CDC59_RS13720 fb2e27806361229e547f471477a30141 524 SUPERFAMILY SSF52335 2 193 3.27E-72 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CDC59_RS13720 fb2e27806361229e547f471477a30141 524 SMART SM00851 14 129 5.4E-65 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CDC59_RS13720 fb2e27806361229e547f471477a30141 524 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 2 524 44.736 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CDC59_RS13720 fb2e27806361229e547f471477a30141 524 SUPERFAMILY SSF53927 215 524 1.1E-124 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CDC59_RS13720 fb2e27806361229e547f471477a30141 524 SMART SM00798 134 456 1.7E-206 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CDC59_RS13720 fb2e27806361229e547f471477a30141 524 PIRSF PIRSF000414 1 524 8.4E-216 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CDC59_RS13720 fb2e27806361229e547f471477a30141 524 Gene3D G3DSA:3.40.140.20 371 514 1.9E-49 T 29-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CDC59_RS13720 fb2e27806361229e547f471477a30141 524 Pfam PF01808 AICARFT/IMPCHase bienzyme 134 454 1.1E-117 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CDC59_RS04215 e2f3bdcbebc3a4c9411ead4867f6ec17 647 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 13 643 28.511 T 29-03-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 CDC59_RS04215 e2f3bdcbebc3a4c9411ead4867f6ec17 647 SMART SM00853 460 603 1.0E-54 T 29-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 CDC59_RS04215 e2f3bdcbebc3a4c9411ead4867f6ec17 647 Pfam PF08676 MutL C terminal dimerisation domain 456 603 7.2E-48 T 29-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 CDC59_RS04215 e2f3bdcbebc3a4c9411ead4867f6ec17 647 SUPERFAMILY SSF55874 13 211 1.44E-52 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS04215 e2f3bdcbebc3a4c9411ead4867f6ec17 647 SUPERFAMILY SSF118116 455 645 1.57E-59 T 29-03-2018 CDC59_RS04215 e2f3bdcbebc3a4c9411ead4867f6ec17 647 SUPERFAMILY SSF54211 199 334 1.25E-35 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CDC59_RS04215 e2f3bdcbebc3a4c9411ead4867f6ec17 647 SMART SM01340 216 334 3.5E-58 T 29-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 CDC59_RS04215 e2f3bdcbebc3a4c9411ead4867f6ec17 647 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 217 333 3.1E-37 T 29-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 CDC59_RS04215 e2f3bdcbebc3a4c9411ead4867f6ec17 647 Gene3D G3DSA:3.30.565.10 8 208 8.2E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS04215 e2f3bdcbebc3a4c9411ead4867f6ec17 647 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 14 314 1.0E-91 T 29-03-2018 IPR002099 DNA mismatch repair protein family GO:0005524|GO:0006298|GO:0030983 CDC59_RS04215 e2f3bdcbebc3a4c9411ead4867f6ec17 647 Gene3D G3DSA:3.30.230.10 221 333 1.3E-29 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CDC59_RS04215 e2f3bdcbebc3a4c9411ead4867f6ec17 647 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 36 134 9.5E-11 T 29-03-2018 CDC59_RS04215 e2f3bdcbebc3a4c9411ead4867f6ec17 647 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 105 111 - T 29-03-2018 IPR014762 DNA mismatch repair, conserved site CDC59_RS15120 d234235a664ab763ccd82d04bf561f22 284 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 5 183 2.6E-63 T 29-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CDC59_RS15120 d234235a664ab763ccd82d04bf561f22 284 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 183 207 - T 29-03-2018 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CDC59_RS15120 d234235a664ab763ccd82d04bf561f22 284 Gene3D G3DSA:3.40.50.720 1 184 3.0E-53 T 29-03-2018 CDC59_RS15120 d234235a664ab763ccd82d04bf561f22 284 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 186 282 7.9E-34 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CDC59_RS15120 d234235a664ab763ccd82d04bf561f22 284 SUPERFAMILY SSF48179 185 283 1.28E-32 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CDC59_RS15120 d234235a664ab763ccd82d04bf561f22 284 PIRSF PIRSF000105 1 284 8.6E-84 T 29-03-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 CDC59_RS15120 d234235a664ab763ccd82d04bf561f22 284 Gene3D G3DSA:1.10.1040.10 185 284 4.1E-33 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CDC59_RS15120 d234235a664ab763ccd82d04bf561f22 284 SUPERFAMILY SSF51735 1 185 3.03E-58 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS18620 2910fc70a66ae8e530a585cf653e84ae 205 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 175 5.9E-23 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS18620 2910fc70a66ae8e530a585cf653e84ae 205 SUPERFAMILY SSF56784 3 204 1.63E-35 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS18620 2910fc70a66ae8e530a585cf653e84ae 205 Gene3D G3DSA:3.40.50.1000 1 192 5.6E-27 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS18220 7081172e59fbbe9e6ba8d525c911446c 323 Gene3D G3DSA:3.40.50.1100 163 323 5.2E-39 T 29-03-2018 CDC59_RS18220 7081172e59fbbe9e6ba8d525c911446c 323 SUPERFAMILY SSF53686 7 315 8.51E-99 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CDC59_RS18220 7081172e59fbbe9e6ba8d525c911446c 323 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 20 307 8.9E-80 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CDC59_RS18220 7081172e59fbbe9e6ba8d525c911446c 323 Gene3D G3DSA:3.40.50.1100 17 162 1.5E-42 T 29-03-2018 CDC59_RS01155 baee1f612c65de2c0021ce06251e0426 138 Hamap MF_00048 UPF0102 protein YraN [yraN]. 18 135 23.652 T 29-03-2018 IPR003509 Uncharacterised protein family UPF0102 CDC59_RS01155 baee1f612c65de2c0021ce06251e0426 138 SUPERFAMILY SSF52980 21 132 1.34E-16 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CDC59_RS01155 baee1f612c65de2c0021ce06251e0426 138 Pfam PF02021 Uncharacterised protein family UPF0102 25 122 2.2E-27 T 29-03-2018 IPR003509 Uncharacterised protein family UPF0102 CDC59_RS01155 baee1f612c65de2c0021ce06251e0426 138 Gene3D G3DSA:3.40.1350.10 24 138 1.6E-35 T 29-03-2018 CDC59_RS01155 baee1f612c65de2c0021ce06251e0426 138 TIGRFAM TIGR00252 TIGR00252: TIGR00252 family protein 18 135 6.2E-29 T 29-03-2018 IPR003509 Uncharacterised protein family UPF0102 CDC59_RS14030 62ff47770c3029de98e82cdd6313dbc8 234 Pfam PF03412 Peptidase C39 family 56 190 7.8E-23 T 29-03-2018 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 CDC59_RS14030 62ff47770c3029de98e82cdd6313dbc8 234 Gene3D G3DSA:3.90.70.10 55 199 2.5E-33 T 29-03-2018 CDC59_RS08185 6c33fb50bb1f15ca69b279d82c8eeb9e 79 Pfam PF17209 Hfq protein 8 69 2.5E-31 T 29-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 CDC59_RS08185 6c33fb50bb1f15ca69b279d82c8eeb9e 79 SUPERFAMILY SSF50182 8 70 1.34E-23 T 29-03-2018 IPR010920 LSM domain CDC59_RS08185 6c33fb50bb1f15ca69b279d82c8eeb9e 79 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 1 65 27.79 T 29-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 CDC59_RS08185 6c33fb50bb1f15ca69b279d82c8eeb9e 79 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 8 65 1.1E-28 T 29-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 CDC59_RS08185 6c33fb50bb1f15ca69b279d82c8eeb9e 79 Gene3D G3DSA:2.30.30.100 5 74 1.5E-32 T 29-03-2018 CDC59_RS20845 b1e625e662e3aa31509b733972121eae 750 Pfam PF02706 Chain length determinant protein 16 108 2.1E-21 T 29-03-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 CDC59_RS20845 b1e625e662e3aa31509b733972121eae 750 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 525 729 1.4E-44 T 29-03-2018 IPR005702 Exopolysaccharide synthesis protein GO:0045226 CDC59_RS20845 b1e625e662e3aa31509b733972121eae 750 Gene3D G3DSA:3.30.1890.10 46 443 3.6E-65 T 29-03-2018 CDC59_RS20845 b1e625e662e3aa31509b733972121eae 750 Pfam PF13807 G-rich domain on putative tyrosine kinase 388 468 6.0E-30 T 29-03-2018 IPR032807 Tyrosine kinase, G-rich domain CDC59_RS20845 b1e625e662e3aa31509b733972121eae 750 Pfam PF13614 AAA domain 554 702 3.2E-14 T 29-03-2018 IPR025669 AAA domain CDC59_RS20845 b1e625e662e3aa31509b733972121eae 750 SUPERFAMILY SSF52540 546 724 1.45E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS20845 b1e625e662e3aa31509b733972121eae 750 TIGRFAM TIGR01005 eps_transp_fam: exopolysaccharide transport protein family 15 750 0.0 T 29-03-2018 IPR005700 Exopolysaccharide transport protein GO:0006859|GO:0015542 CDC59_RS20845 b1e625e662e3aa31509b733972121eae 750 Gene3D G3DSA:3.40.50.300 542 730 1.9E-38 T 29-03-2018 CDC59_RS12300 f1f39986b43e9e369342bce2c7a1d146 283 Hamap MF_00158 Pantothenate synthetase [panC]. 2 283 37.814 T 29-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 CDC59_RS12300 f1f39986b43e9e369342bce2c7a1d146 283 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 19 76 3.2E-8 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CDC59_RS12300 f1f39986b43e9e369342bce2c7a1d146 283 Pfam PF02569 Pantoate-beta-alanine ligase 3 281 4.7E-97 T 29-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 CDC59_RS12300 f1f39986b43e9e369342bce2c7a1d146 283 Gene3D G3DSA:3.30.1300.10 172 283 2.1E-28 T 29-03-2018 CDC59_RS12300 f1f39986b43e9e369342bce2c7a1d146 283 Gene3D G3DSA:3.40.50.620 1 170 1.6E-70 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDC59_RS12300 f1f39986b43e9e369342bce2c7a1d146 283 SUPERFAMILY SSF52374 1 283 4.69E-96 T 29-03-2018 CDC59_RS12300 f1f39986b43e9e369342bce2c7a1d146 283 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 1 282 3.4E-89 T 29-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 CDC59_RS07760 b3a0830362386ce1a58424c10617fff7 400 Gene3D G3DSA:3.40.50.620 3 272 6.9E-70 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDC59_RS07760 b3a0830362386ce1a58424c10617fff7 400 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 145 166 6.6E-22 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CDC59_RS07760 b3a0830362386ce1a58424c10617fff7 400 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 67 86 6.6E-22 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CDC59_RS07760 b3a0830362386ce1a58424c10617fff7 400 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 16 32 6.6E-22 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CDC59_RS07760 b3a0830362386ce1a58424c10617fff7 400 SUPERFAMILY SSF52374 3 172 1.3E-85 T 29-03-2018 CDC59_RS07760 b3a0830362386ce1a58424c10617fff7 400 SUPERFAMILY SSF52374 243 397 1.3E-85 T 29-03-2018 CDC59_RS07760 b3a0830362386ce1a58424c10617fff7 400 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 4 173 1.4E-55 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CDC59_RS07760 b3a0830362386ce1a58424c10617fff7 400 Pfam PF00579 tRNA synthetases class I (W and Y) 5 170 2.8E-47 T 29-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDC59_RS07760 b3a0830362386ce1a58424c10617fff7 400 Pfam PF00579 tRNA synthetases class I (W and Y) 244 342 1.7E-9 T 29-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDC59_RS07760 b3a0830362386ce1a58424c10617fff7 400 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 12 21 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDC59_RS07760 b3a0830362386ce1a58424c10617fff7 400 Gene3D G3DSA:1.10.240.10 273 393 1.2E-26 T 29-03-2018 CDC59_RS16015 b39a7a8280b7736b42610aabd63c45e1 898 Pfam PF08448 PAS fold 482 592 4.5E-7 T 29-03-2018 IPR013656 PAS fold-4 CDC59_RS16015 b39a7a8280b7736b42610aabd63c45e1 898 Pfam PF08448 PAS fold 610 716 2.1E-20 T 29-03-2018 IPR013656 PAS fold-4 CDC59_RS16015 b39a7a8280b7736b42610aabd63c45e1 898 Pfam PF08448 PAS fold 362 469 1.3E-11 T 29-03-2018 IPR013656 PAS fold-4 CDC59_RS16015 b39a7a8280b7736b42610aabd63c45e1 898 SMART SM00091 355 421 2.8E-12 T 29-03-2018 IPR000014 PAS domain CDC59_RS16015 b39a7a8280b7736b42610aabd63c45e1 898 SMART SM00091 476 542 0.0028 T 29-03-2018 IPR000014 PAS domain CDC59_RS16015 b39a7a8280b7736b42610aabd63c45e1 898 SMART SM00091 603 669 7.4E-4 T 29-03-2018 IPR000014 PAS domain CDC59_RS16015 b39a7a8280b7736b42610aabd63c45e1 898 SMART SM00304 300 355 0.0078 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CDC59_RS16015 b39a7a8280b7736b42610aabd63c45e1 898 SMART SM00267 715 887 3.4E-56 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS16015 b39a7a8280b7736b42610aabd63c45e1 898 Gene3D G3DSA:3.30.450.20 476 596 4.8E-18 T 29-03-2018 CDC59_RS16015 b39a7a8280b7736b42610aabd63c45e1 898 SUPERFAMILY SSF55785 343 466 1.61E-20 T 29-03-2018 IPR000014 PAS domain CDC59_RS16015 b39a7a8280b7736b42610aabd63c45e1 898 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 723 886 3.1E-40 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS16015 b39a7a8280b7736b42610aabd63c45e1 898 Pfam PF02743 Cache domain 38 224 2.2E-18 T 29-03-2018 IPR033479 Double Cache domain 1 CDC59_RS16015 b39a7a8280b7736b42610aabd63c45e1 898 SUPERFAMILY SSF55073 731 888 7.85E-47 T 29-03-2018 IPR029787 Nucleotide cyclase CDC59_RS16015 b39a7a8280b7736b42610aabd63c45e1 898 SUPERFAMILY SSF55785 588 713 7.33E-20 T 29-03-2018 IPR000014 PAS domain CDC59_RS16015 b39a7a8280b7736b42610aabd63c45e1 898 Gene3D G3DSA:3.30.450.20 332 475 5.1E-25 T 29-03-2018 CDC59_RS16015 b39a7a8280b7736b42610aabd63c45e1 898 Gene3D G3DSA:3.30.450.20 597 723 1.1E-24 T 29-03-2018 CDC59_RS16015 b39a7a8280b7736b42610aabd63c45e1 898 Gene3D G3DSA:3.30.450.20 34 162 8.2E-18 T 29-03-2018 CDC59_RS16015 b39a7a8280b7736b42610aabd63c45e1 898 Pfam PF00990 Diguanylate cyclase, GGDEF domain 727 881 1.3E-43 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS16015 b39a7a8280b7736b42610aabd63c45e1 898 Gene3D G3DSA:3.30.70.270 724 890 1.0E-58 T 29-03-2018 CDC59_RS16015 b39a7a8280b7736b42610aabd63c45e1 898 SUPERFAMILY SSF55785 487 600 1.4E-12 T 29-03-2018 IPR000014 PAS domain CDC59_RS16015 b39a7a8280b7736b42610aabd63c45e1 898 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 600 720 5.6E-6 T 29-03-2018 IPR000014 PAS domain CDC59_RS16015 b39a7a8280b7736b42610aabd63c45e1 898 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 477 598 4.8E-9 T 29-03-2018 IPR000014 PAS domain CDC59_RS16015 b39a7a8280b7736b42610aabd63c45e1 898 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 354 474 1.3E-10 T 29-03-2018 IPR000014 PAS domain CDC59_RS16015 b39a7a8280b7736b42610aabd63c45e1 898 Gene3D G3DSA:3.30.450.20 163 279 5.0E-10 T 29-03-2018 CDC59_RS13460 b28d19d93c75d2fede8bb07c066d9920 514 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 391 503 3.8E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS13460 b28d19d93c75d2fede8bb07c066d9920 514 Gene3D G3DSA:3.30.565.10 350 505 9.7E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS13460 b28d19d93c75d2fede8bb07c066d9920 514 SMART SM00387 389 506 1.3E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS13460 b28d19d93c75d2fede8bb07c066d9920 514 Gene3D G3DSA:1.10.287.130 268 339 1.4E-14 T 29-03-2018 CDC59_RS13460 b28d19d93c75d2fede8bb07c066d9920 514 Gene3D G3DSA:1.20.5.1040 182 225 9.9E-9 T 29-03-2018 CDC59_RS13460 b28d19d93c75d2fede8bb07c066d9920 514 Gene3D G3DSA:1.20.5.1040 45 98 2.3E-4 T 29-03-2018 CDC59_RS13460 b28d19d93c75d2fede8bb07c066d9920 514 Pfam PF08521 Two-component sensor kinase N-terminal 59 201 1.2E-45 T 29-03-2018 IPR013727 Two-component sensor kinase, N-terminal CDC59_RS13460 b28d19d93c75d2fede8bb07c066d9920 514 SUPERFAMILY SSF55874 333 507 5.24E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS13460 b28d19d93c75d2fede8bb07c066d9920 514 SUPERFAMILY SSF47384 261 342 4.51E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS13460 b28d19d93c75d2fede8bb07c066d9920 514 SMART SM00304 225 277 2.1E-4 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CDC59_RS13460 b28d19d93c75d2fede8bb07c066d9920 514 SMART SM00388 278 343 1.5E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS13460 b28d19d93c75d2fede8bb07c066d9920 514 Pfam PF00512 His Kinase A (phospho-acceptor) domain 279 342 7.2E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS13460 b28d19d93c75d2fede8bb07c066d9920 514 PRINTS PR00344 Bacterial sensor protein C-terminal signature 490 503 2.4E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS13460 b28d19d93c75d2fede8bb07c066d9920 514 PRINTS PR00344 Bacterial sensor protein C-terminal signature 428 442 2.4E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS13460 b28d19d93c75d2fede8bb07c066d9920 514 PRINTS PR00344 Bacterial sensor protein C-terminal signature 460 478 2.4E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS17050 c587391a9bfc7f984b3215e324056d4d 642 Gene3D G3DSA:3.90.20.10 15 229 9.6E-6 T 29-03-2018 CDC59_RS17050 c587391a9bfc7f984b3215e324056d4d 642 TIGRFAM TIGR02492 flgK_ends: flagellar hook-associated protein FlgK 4 356 2.1E-80 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CDC59_RS17050 c587391a9bfc7f984b3215e324056d4d 642 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 594 638 3.4E-11 T 29-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CDC59_RS17050 c587391a9bfc7f984b3215e324056d4d 642 SUPERFAMILY SSF64518 434 638 1.31E-23 T 29-03-2018 CDC59_RS17050 c587391a9bfc7f984b3215e324056d4d 642 Pfam PF00460 Flagella basal body rod protein 6 35 1.6E-6 T 29-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CDC59_RS17050 c587391a9bfc7f984b3215e324056d4d 642 Gene3D G3DSA:2.60.40.10 296 496 0.25 T 29-03-2018 IPR013783 Immunoglobulin-like fold CDC59_RS17050 c587391a9bfc7f984b3215e324056d4d 642 SUPERFAMILY SSF64518 132 421 5.49E-20 T 29-03-2018 CDC59_RS17050 c587391a9bfc7f984b3215e324056d4d 642 PRINTS PR01005 Flagellar hook-associated protein signature 12 35 3.1E-27 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CDC59_RS17050 c587391a9bfc7f984b3215e324056d4d 642 PRINTS PR01005 Flagellar hook-associated protein signature 124 144 3.1E-27 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CDC59_RS17050 c587391a9bfc7f984b3215e324056d4d 642 PRINTS PR01005 Flagellar hook-associated protein signature 217 235 3.1E-27 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CDC59_RS17050 c587391a9bfc7f984b3215e324056d4d 642 PRINTS PR01005 Flagellar hook-associated protein signature 157 181 3.1E-27 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CDC59_RS17050 c587391a9bfc7f984b3215e324056d4d 642 PRINTS PR01005 Flagellar hook-associated protein signature 360 382 3.1E-27 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CDC59_RS17050 c587391a9bfc7f984b3215e324056d4d 642 PRINTS PR01005 Flagellar hook-associated protein signature 50 72 3.1E-27 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CDC59_RS17050 c587391a9bfc7f984b3215e324056d4d 642 PRINTS PR01005 Flagellar hook-associated protein signature 260 282 3.1E-27 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CDC59_RS17050 c587391a9bfc7f984b3215e324056d4d 642 PRINTS PR01005 Flagellar hook-associated protein signature 406 423 3.1E-27 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CDC59_RS16685 470f1690d143566c012d26c2e0996202 131 Gene3D G3DSA:3.40.30.10 7 107 5.6E-8 T 29-03-2018 CDC59_RS16685 470f1690d143566c012d26c2e0996202 131 SUPERFAMILY SSF52833 21 94 2.73E-8 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS04040 33c255c1b6f12037d65b4ec459ebff17 237 Gene3D G3DSA:1.10.10.10 2 73 1.5E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS04040 33c255c1b6f12037d65b4ec459ebff17 237 SUPERFAMILY SSF46785 7 78 7.71E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS04040 33c255c1b6f12037d65b4ec459ebff17 237 Pfam PF07702 UTRA domain 95 232 1.3E-31 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CDC59_RS04040 33c255c1b6f12037d65b4ec459ebff17 237 SUPERFAMILY SSF64288 64 234 2.98E-40 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CDC59_RS04040 33c255c1b6f12037d65b4ec459ebff17 237 TIGRFAM TIGR02018 his_ut_repres: histidine utilization repressor 10 237 3.8E-98 T 29-03-2018 IPR010248 Histidine utilization repressor GO:0003677|GO:0006547|GO:0045892 CDC59_RS04040 33c255c1b6f12037d65b4ec459ebff17 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 3.5E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDC59_RS04040 33c255c1b6f12037d65b4ec459ebff17 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 3.5E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDC59_RS04040 33c255c1b6f12037d65b4ec459ebff17 237 Gene3D G3DSA:3.40.1410.10 74 237 2.6E-40 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CDC59_RS04040 33c255c1b6f12037d65b4ec459ebff17 237 SMART SM00866 95 232 3.3E-30 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CDC59_RS04040 33c255c1b6f12037d65b4ec459ebff17 237 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 74 7.6E-21 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDC59_RS04040 33c255c1b6f12037d65b4ec459ebff17 237 SMART SM00345 15 74 3.2E-20 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDC59_RS12110 07eb0adacf1f18afe9f62c888fe9b36d 175 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 66 72 - T 29-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 CDC59_RS12110 07eb0adacf1f18afe9f62c888fe9b36d 175 Gene3D G3DSA:3.90.80.10 1 175 1.2E-55 T 29-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 CDC59_RS12110 07eb0adacf1f18afe9f62c888fe9b36d 175 SUPERFAMILY SSF50324 3 175 1.2E-67 T 29-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 CDC59_RS12110 07eb0adacf1f18afe9f62c888fe9b36d 175 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 14 174 35.248 T 29-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 CDC59_RS12110 07eb0adacf1f18afe9f62c888fe9b36d 175 Pfam PF00719 Inorganic pyrophosphatase 18 174 9.3E-53 T 29-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 CDC59_RS02320 4dd80ce13cbfbce280e4cdb8ce79a9fd 172 Gene3D G3DSA:3.30.230.10 82 172 5.0E-34 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CDC59_RS02320 4dd80ce13cbfbce280e4cdb8ce79a9fd 172 SUPERFAMILY SSF54211 85 165 9.1E-27 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CDC59_RS02320 4dd80ce13cbfbce280e4cdb8ce79a9fd 172 Pfam PF00333 Ribosomal protein S5, N-terminal domain 17 81 5.4E-25 T 29-03-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 CDC59_RS02320 4dd80ce13cbfbce280e4cdb8ce79a9fd 172 SUPERFAMILY SSF54768 12 82 2.3E-21 T 29-03-2018 CDC59_RS02320 4dd80ce13cbfbce280e4cdb8ce79a9fd 172 ProSitePatterns PS00585 Ribosomal protein S5 signature. 34 66 - T 29-03-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site CDC59_RS02320 4dd80ce13cbfbce280e4cdb8ce79a9fd 172 Gene3D G3DSA:3.30.160.20 16 78 2.3E-22 T 29-03-2018 CDC59_RS02320 4dd80ce13cbfbce280e4cdb8ce79a9fd 172 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 169 34.77 T 29-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 CDC59_RS02320 4dd80ce13cbfbce280e4cdb8ce79a9fd 172 Pfam PF03719 Ribosomal protein S5, C-terminal domain 93 163 2.3E-30 T 29-03-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 CDC59_RS02320 4dd80ce13cbfbce280e4cdb8ce79a9fd 172 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 16 169 2.0E-65 T 29-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 CDC59_RS03585 7824c53c6343655983f6e56a712a839b 358 Pfam PF06144 DNA polymerase III, delta subunit 24 201 2.3E-18 T 29-03-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 CDC59_RS03585 7824c53c6343655983f6e56a712a839b 358 Gene3D G3DSA:1.10.8.60 150 234 2.3E-23 T 29-03-2018 CDC59_RS03585 7824c53c6343655983f6e56a712a839b 358 Pfam PF14840 Processivity clamp loader gamma complex DNA pol III C-term 227 326 4.5E-11 T 29-03-2018 IPR032780 DNA polymerase III subunit delta, C-terminal KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDC59_RS03585 7824c53c6343655983f6e56a712a839b 358 SUPERFAMILY SSF52540 12 222 7.96E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS03585 7824c53c6343655983f6e56a712a839b 358 SUPERFAMILY SSF48019 224 351 1.87E-29 T 29-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CDC59_RS03585 7824c53c6343655983f6e56a712a839b 358 Gene3D G3DSA:1.20.272.10 235 355 2.0E-30 T 29-03-2018 CDC59_RS03585 7824c53c6343655983f6e56a712a839b 358 Gene3D G3DSA:3.40.50.300 1 147 7.3E-18 T 29-03-2018 CDC59_RS03585 7824c53c6343655983f6e56a712a839b 358 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 20 349 5.5E-81 T 29-03-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 CDC59_RS03060 1c7ae62e2a07de0538d834e6891086d1 384 Pfam PF10023 Putative aminopeptidase 26 348 1.0E-131 T 29-03-2018 IPR014553 Predicted aminopeptidase CDC59_RS03060 1c7ae62e2a07de0538d834e6891086d1 384 PIRSF PIRSF029285 2 355 9.0E-165 T 29-03-2018 IPR014553 Predicted aminopeptidase CDC59_RS08075 4f6f379468fac7ace8cfc9d5a33a58c0 349 Gene3D G3DSA:3.40.190.10 143 345 3.1E-30 T 29-03-2018 CDC59_RS08075 4f6f379468fac7ace8cfc9d5a33a58c0 349 SUPERFAMILY SSF53850 38 289 7.92E-47 T 29-03-2018 CDC59_RS08075 4f6f379468fac7ace8cfc9d5a33a58c0 349 Pfam PF13379 NMT1-like family 34 267 1.4E-31 T 29-03-2018 CDC59_RS08075 4f6f379468fac7ace8cfc9d5a33a58c0 349 Gene3D G3DSA:3.40.190.10 35 142 3.5E-15 T 29-03-2018 CDC59_RS08075 4f6f379468fac7ace8cfc9d5a33a58c0 349 SMART SM00062 39 280 0.0023 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CDC59_RS18350 7e48cd7b804e2e92b915917df5c07add 227 SUPERFAMILY SSF103501 1 227 1.03E-63 T 29-03-2018 IPR023234 NarG-like domain CDC59_RS18350 7e48cd7b804e2e92b915917df5c07add 227 Gene3D G3DSA:1.20.950.20 1 216 4.7E-40 T 29-03-2018 CDC59_RS18350 7e48cd7b804e2e92b915917df5c07add 227 Pfam PF02665 Nitrate reductase gamma subunit 5 227 1.3E-78 T 29-03-2018 IPR023234 NarG-like domain CDC59_RS18350 7e48cd7b804e2e92b915917df5c07add 227 TIGRFAM TIGR00351 narI: respiratory nitrate reductase, gamma subunit 1 227 1.1E-73 T 29-03-2018 IPR003816 Nitrate reductase, gamma subunit GO:0008940|GO:0009325|GO:0055114 KEGG: 00910+1.7.99.4 CDC59_RS08650 a7d822f0dd65b10a2cf087a519667f24 216 Pfam PF01726 LexA DNA binding domain 1 65 7.4E-28 T 29-03-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 CDC59_RS08650 a7d822f0dd65b10a2cf087a519667f24 216 SUPERFAMILY SSF46785 3 69 2.53E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS08650 a7d822f0dd65b10a2cf087a519667f24 216 Hamap MF_00015 LexA repressor [lexA]. 3 214 33.228 T 29-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 CDC59_RS08650 a7d822f0dd65b10a2cf087a519667f24 216 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 126 136 4.1E-12 T 29-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CDC59_RS08650 a7d822f0dd65b10a2cf087a519667f24 216 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 165 177 4.1E-12 T 29-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CDC59_RS08650 a7d822f0dd65b10a2cf087a519667f24 216 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 137 148 4.1E-12 T 29-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CDC59_RS08650 a7d822f0dd65b10a2cf087a519667f24 216 Gene3D G3DSA:1.10.10.10 1 70 1.0E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS08650 a7d822f0dd65b10a2cf087a519667f24 216 Pfam PF00717 Peptidase S24-like 129 195 1.4E-14 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CDC59_RS08650 a7d822f0dd65b10a2cf087a519667f24 216 TIGRFAM TIGR00498 lexA: repressor LexA 1 213 1.8E-70 T 29-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 CDC59_RS08650 a7d822f0dd65b10a2cf087a519667f24 216 SUPERFAMILY SSF51306 90 212 2.96E-35 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CDC59_RS08650 a7d822f0dd65b10a2cf087a519667f24 216 Gene3D G3DSA:2.10.109.10 95 214 8.4E-24 T 29-03-2018 CDC59_RS12175 243041c04249d518c086a270295405ba 215 SUPERFAMILY SSF88659 138 212 8.78E-17 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS12175 243041c04249d518c086a270295405ba 215 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 48 212 2.8E-29 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS12175 243041c04249d518c086a270295405ba 215 Gene3D G3DSA:1.10.10.10 140 215 4.5E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS12175 243041c04249d518c086a270295405ba 215 Pfam PF04542 Sigma-70 region 2 53 120 8.9E-16 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS12175 243041c04249d518c086a270295405ba 215 Gene3D G3DSA:1.10.1740.10 26 139 8.6E-23 T 29-03-2018 CDC59_RS12175 243041c04249d518c086a270295405ba 215 Pfam PF04545 Sigma-70, region 4 161 210 8.4E-15 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS12175 243041c04249d518c086a270295405ba 215 SUPERFAMILY SSF88946 32 131 2.75E-24 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS03445 6b9f25fd522e364f64b2427533cf799c 461 Pfam PF01225 Mur ligase family, catalytic domain 2 100 8.3E-21 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CDC59_RS03445 6b9f25fd522e364f64b2427533cf799c 461 Gene3D G3DSA:3.90.190.20 315 460 5.0E-30 T 29-03-2018 CDC59_RS03445 6b9f25fd522e364f64b2427533cf799c 461 Hamap MF_02020 UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptandioate ligase [mpl]. 1 454 59.878 T 29-03-2018 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 CDC59_RS03445 6b9f25fd522e364f64b2427533cf799c 461 Pfam PF02875 Mur ligase family, glutamate ligase domain 312 360 7.9E-11 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CDC59_RS03445 6b9f25fd522e364f64b2427533cf799c 461 Pfam PF08245 Mur ligase middle domain 108 292 6.7E-25 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CDC59_RS03445 6b9f25fd522e364f64b2427533cf799c 461 SUPERFAMILY SSF53623 98 309 1.7E-55 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CDC59_RS03445 6b9f25fd522e364f64b2427533cf799c 461 Gene3D G3DSA:3.40.1190.10 91 314 1.2E-48 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CDC59_RS03445 6b9f25fd522e364f64b2427533cf799c 461 SUPERFAMILY SSF53244 312 453 1.31E-37 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CDC59_RS03445 6b9f25fd522e364f64b2427533cf799c 461 TIGRFAM TIGR01081 mpl: UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase 2 453 2.7E-225 T 29-03-2018 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 CDC59_RS03445 6b9f25fd522e364f64b2427533cf799c 461 SUPERFAMILY SSF51984 1 90 6.41E-22 T 29-03-2018 CDC59_RS03445 6b9f25fd522e364f64b2427533cf799c 461 Gene3D G3DSA:3.40.50.720 1 90 2.4E-13 T 29-03-2018 CDC59_RS03710 c54ee6dbfa1a56238606d239fdd449e7 198 SUPERFAMILY SSF101874 22 191 1.31E-46 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CDC59_RS03710 c54ee6dbfa1a56238606d239fdd449e7 198 SMART SM00867 24 189 5.2E-57 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CDC59_RS03710 c54ee6dbfa1a56238606d239fdd449e7 198 Gene3D G3DSA:2.40.128.110 23 197 7.2E-44 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CDC59_RS03710 c54ee6dbfa1a56238606d239fdd449e7 198 Pfam PF04264 YceI-like domain 25 186 2.1E-33 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CDC59_RS06455 d7be274bdae8493b57b1f659ad61a17c 67 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 57 3.5E-17 T 29-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDC59_RS06455 d7be274bdae8493b57b1f659ad61a17c 67 SMART SM01409 8 59 1.1E-15 T 29-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CDC59_RS06455 d7be274bdae8493b57b1f659ad61a17c 67 Pfam PF01192 RNA polymerase Rpb6 8 58 8.7E-15 T 29-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CDC59_RS06455 d7be274bdae8493b57b1f659ad61a17c 67 Gene3D G3DSA:3.90.940.10 1 67 3.9E-20 T 29-03-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CDC59_RS06455 d7be274bdae8493b57b1f659ad61a17c 67 SUPERFAMILY SSF63562 1 63 7.15E-20 T 29-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CDC59_RS06455 d7be274bdae8493b57b1f659ad61a17c 67 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 60 15.774 T 29-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDC59_RS08010 0b53fcfa2a72b38979326a78ee12760e 458 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 233 248 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CDC59_RS08010 0b53fcfa2a72b38979326a78ee12760e 458 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 360 369 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site CDC59_RS08010 0b53fcfa2a72b38979326a78ee12760e 458 Pfam PF02954 Bacterial regulatory protein, Fis family 405 445 7.7E-7 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CDC59_RS08010 0b53fcfa2a72b38979326a78ee12760e 458 SUPERFAMILY SSF46689 360 447 2.15E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS08010 0b53fcfa2a72b38979326a78ee12760e 458 SUPERFAMILY SSF52540 149 388 6.76E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS08010 0b53fcfa2a72b38979326a78ee12760e 458 SMART SM00382 167 310 3.3E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS08010 0b53fcfa2a72b38979326a78ee12760e 458 Gene3D G3DSA:1.10.10.60 407 452 4.3E-13 T 29-03-2018 CDC59_RS08010 0b53fcfa2a72b38979326a78ee12760e 458 Gene3D G3DSA:3.40.50.300 141 318 1.3E-22 T 29-03-2018 CDC59_RS08010 0b53fcfa2a72b38979326a78ee12760e 458 Pfam PF00158 Sigma-54 interaction domain 148 313 1.4E-65 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CDC59_RS08010 0b53fcfa2a72b38979326a78ee12760e 458 Gene3D G3DSA:1.10.8.60 319 406 4.9E-22 T 29-03-2018 CDC59_RS10935 a9bb72a9538d9ee34538e95891777326 265 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 34 47 - T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CDC59_RS10935 a9bb72a9538d9ee34538e95891777326 265 Pfam PF00809 Pterin binding enzyme 1 240 2.8E-81 T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CDC59_RS10935 a9bb72a9538d9ee34538e95891777326 265 Gene3D G3DSA:3.20.20.20 1 259 6.0E-106 T 29-03-2018 CDC59_RS10935 a9bb72a9538d9ee34538e95891777326 265 SUPERFAMILY SSF51717 1 257 1.44E-96 T 29-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CDC59_RS10935 a9bb72a9538d9ee34538e95891777326 265 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 1 254 7.9E-95 T 29-03-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 CDC59_RS01255 b9267675a4417bd1a32cb67e504f552c 1013 Gene3D G3DSA:2.40.128.130 694 1013 3.4E-45 T 29-03-2018 CDC59_RS01255 b9267675a4417bd1a32cb67e504f552c 1013 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 500 1010 1.2E-25 T 29-03-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 CDC59_RS01255 b9267675a4417bd1a32cb67e504f552c 1013 SMART SM00869 734 1003 4.8E-51 T 29-03-2018 IPR005546 Autotransporter beta-domain CDC59_RS01255 b9267675a4417bd1a32cb67e504f552c 1013 Pfam PF03797 Autotransporter beta-domain 737 993 4.4E-59 T 29-03-2018 IPR005546 Autotransporter beta-domain CDC59_RS01255 b9267675a4417bd1a32cb67e504f552c 1013 SUPERFAMILY SSF103515 701 1013 1.06E-51 T 29-03-2018 IPR005546 Autotransporter beta-domain CDC59_RS08940 ef1c98ed14c87b368fbe0f092ac9054e 233 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 111 124 2.1E-30 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDC59_RS08940 ef1c98ed14c87b368fbe0f092ac9054e 233 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 4 15 2.1E-30 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDC59_RS08940 ef1c98ed14c87b368fbe0f092ac9054e 233 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 142 158 2.1E-30 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDC59_RS08940 ef1c98ed14c87b368fbe0f092ac9054e 233 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 30 43 2.1E-30 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDC59_RS08940 ef1c98ed14c87b368fbe0f092ac9054e 233 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 160 180 2.1E-30 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDC59_RS08940 ef1c98ed14c87b368fbe0f092ac9054e 233 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 187 200 2.1E-30 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDC59_RS08940 ef1c98ed14c87b368fbe0f092ac9054e 233 Gene3D G3DSA:1.10.150.240 19 87 2.4E-28 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CDC59_RS08940 ef1c98ed14c87b368fbe0f092ac9054e 233 Gene3D G3DSA:3.40.50.1000 88 233 1.1E-23 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS08940 ef1c98ed14c87b368fbe0f092ac9054e 233 SUPERFAMILY SSF56784 4 226 1.02E-46 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS08940 ef1c98ed14c87b368fbe0f092ac9054e 233 Pfam PF00702 haloacid dehalogenase-like hydrolase 4 185 3.7E-10 T 29-03-2018 CDC59_RS08940 ef1c98ed14c87b368fbe0f092ac9054e 233 TIGRFAM TIGR01493 HAD-SF-IA-v2: HAD hydrolase, family IA, variant 2 6 189 2.5E-26 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDC59_RS08940 ef1c98ed14c87b368fbe0f092ac9054e 233 TIGRFAM TIGR01428 HAD_type_II: haloacid dehalogenase, type II 4 204 2.2E-71 T 29-03-2018 IPR006328 L-2-Haloacid dehalogenase GO:0008152|GO:0019120 KEGG: 00361+3.8.1.2|KEGG: 00625+3.8.1.2|MetaCyc: PWY-7425 CDC59_RS04430 97384861db618385bcba174e73bc194c 190 SUPERFAMILY SSF143456 8 190 6.15E-67 T 29-03-2018 CDC59_RS04430 97384861db618385bcba174e73bc194c 190 Gene3D G3DSA:3.30.70.1300 49 123 5.7E-32 T 29-03-2018 CDC59_RS04430 97384861db618385bcba174e73bc194c 190 Gene3D G3DSA:3.40.1740.10 124 182 8.3E-11 T 29-03-2018 CDC59_RS04430 97384861db618385bcba174e73bc194c 190 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 8 190 38.85 T 29-03-2018 IPR003774 Protein of unknown function UPF0301 CDC59_RS04430 97384861db618385bcba174e73bc194c 190 Pfam PF02622 Uncharacterized ACR, COG1678 19 177 4.6E-50 T 29-03-2018 IPR003774 Protein of unknown function UPF0301 CDC59_RS12640 d851d93d5ed253bf881701054b130f05 959 Pfam PF08264 Anticodon-binding domain of tRNA 716 872 4.8E-23 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CDC59_RS12640 d851d93d5ed253bf881701054b130f05 959 Gene3D G3DSA:3.30.2320.20 847 918 3.8E-20 T 29-03-2018 CDC59_RS12640 d851d93d5ed253bf881701054b130f05 959 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 35 671 3.0E-180 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDC59_RS12640 d851d93d5ed253bf881701054b130f05 959 Pfam PF06827 Zinc finger found in FPG and IleRS 921 946 5.4E-8 T 29-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 CDC59_RS12640 d851d93d5ed253bf881701054b130f05 959 Gene3D G3DSA:3.90.740.10 205 406 6.8E-53 T 29-03-2018 CDC59_RS12640 d851d93d5ed253bf881701054b130f05 959 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 23 873 1.4E-257 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CDC59_RS12640 d851d93d5ed253bf881701054b130f05 959 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 10 950 20.083 T 29-03-2018 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 CDC59_RS12640 d851d93d5ed253bf881701054b130f05 959 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 59 70 2.4E-26 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CDC59_RS12640 d851d93d5ed253bf881701054b130f05 959 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 246 269 2.4E-26 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CDC59_RS12640 d851d93d5ed253bf881701054b130f05 959 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 416 431 2.4E-26 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CDC59_RS12640 d851d93d5ed253bf881701054b130f05 959 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 592 601 2.4E-26 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CDC59_RS12640 d851d93d5ed253bf881701054b130f05 959 SUPERFAMILY SSF52374 21 209 3.22E-121 T 29-03-2018 CDC59_RS12640 d851d93d5ed253bf881701054b130f05 959 SUPERFAMILY SSF52374 418 680 3.22E-121 T 29-03-2018 CDC59_RS12640 d851d93d5ed253bf881701054b130f05 959 SUPERFAMILY SSF50677 234 418 2.51E-48 T 29-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CDC59_RS12640 d851d93d5ed253bf881701054b130f05 959 Gene3D G3DSA:3.40.50.620 50 134 4.6E-25 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDC59_RS12640 d851d93d5ed253bf881701054b130f05 959 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 66 77 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDC59_RS12640 d851d93d5ed253bf881701054b130f05 959 SUPERFAMILY SSF47323 683 949 4.3E-71 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDC59_RS12640 d851d93d5ed253bf881701054b130f05 959 Gene3D G3DSA:1.10.730.10 627 846 1.4E-50 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDC59_RS12640 d851d93d5ed253bf881701054b130f05 959 Gene3D G3DSA:3.40.50.620 407 626 5.7E-48 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDC59_RS17065 991d9816b6ac1cc74cb8a11cd97f4fe0 419 Gene3D G3DSA:3.50.50.60 3 393 1.6E-38 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS17065 991d9816b6ac1cc74cb8a11cd97f4fe0 419 Pfam PF01494 FAD binding domain 14 262 2.1E-20 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 CDC59_RS17065 991d9816b6ac1cc74cb8a11cd97f4fe0 419 SUPERFAMILY SSF51905 290 387 2.75E-46 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS17065 991d9816b6ac1cc74cb8a11cd97f4fe0 419 SUPERFAMILY SSF51905 12 182 2.75E-46 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS14515 3a04bfb193951256ff0f081691c5dbcc 538 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 53 384 7.7E-96 T 29-03-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 CDC59_RS14515 3a04bfb193951256ff0f081691c5dbcc 538 Gene3D G3DSA:3.90.226.10 175 470 2.4E-66 T 29-03-2018 CDC59_RS14515 3a04bfb193951256ff0f081691c5dbcc 538 Pfam PF03572 Peptidase family S41 200 381 1.2E-51 T 29-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 CDC59_RS14515 3a04bfb193951256ff0f081691c5dbcc 538 SMART SM00245 174 382 3.1E-56 T 29-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 CDC59_RS14515 3a04bfb193951256ff0f081691c5dbcc 538 SUPERFAMILY SSF50156 95 185 6.02E-21 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CDC59_RS14515 3a04bfb193951256ff0f081691c5dbcc 538 Pfam PF13180 PDZ domain 101 180 1.4E-14 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CDC59_RS14515 3a04bfb193951256ff0f081691c5dbcc 538 Gene3D G3DSA:3.30.750.44 40 108 5.6E-16 T 29-03-2018 CDC59_RS14515 3a04bfb193951256ff0f081691c5dbcc 538 Gene3D G3DSA:2.30.42.10 109 174 1.9E-20 T 29-03-2018 CDC59_RS14515 3a04bfb193951256ff0f081691c5dbcc 538 SMART SM00228 101 172 4.6E-18 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CDC59_RS14515 3a04bfb193951256ff0f081691c5dbcc 538 SUPERFAMILY SSF52096 193 386 3.31E-76 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CDC59_RS14515 3a04bfb193951256ff0f081691c5dbcc 538 SUPERFAMILY SSF52096 30 119 3.31E-76 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CDC59_RS09850 10a61e1d5b56b20cc7a5e0d54285e31f 355 SMART SM00354 2 72 6.2E-26 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDC59_RS09850 10a61e1d5b56b20cc7a5e0d54285e31f 355 SUPERFAMILY SSF47413 4 60 1.09E-15 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDC59_RS09850 10a61e1d5b56b20cc7a5e0d54285e31f 355 SUPERFAMILY SSF53822 59 324 1.5E-65 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CDC59_RS09850 10a61e1d5b56b20cc7a5e0d54285e31f 355 Gene3D G3DSA:1.10.260.40 4 58 4.7E-20 T 29-03-2018 CDC59_RS09850 10a61e1d5b56b20cc7a5e0d54285e31f 355 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 1.5E-16 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDC59_RS09850 10a61e1d5b56b20cc7a5e0d54285e31f 355 Gene3D G3DSA:3.40.50.2300 59 173 4.8E-30 T 29-03-2018 CDC59_RS09850 10a61e1d5b56b20cc7a5e0d54285e31f 355 Gene3D G3DSA:3.40.50.2300 174 335 1.4E-39 T 29-03-2018 CDC59_RS09850 10a61e1d5b56b20cc7a5e0d54285e31f 355 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 62 315 5.8E-34 T 29-03-2018 IPR001761 Periplasmic binding protein/LacI sugar binding domain CDC59_RS14390 ed31d37628ce1d2a39d57817cfaab3a7 337 Pfam PF02885 Glycosyl transferase family, helical bundle domain 35 86 1.1E-11 T 29-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CDC59_RS14390 ed31d37628ce1d2a39d57817cfaab3a7 337 SUPERFAMILY SSF47648 27 93 1.1E-14 T 29-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CDC59_RS14390 ed31d37628ce1d2a39d57817cfaab3a7 337 Gene3D G3DSA:1.20.970.10 17 102 2.4E-16 T 29-03-2018 CDC59_RS14390 ed31d37628ce1d2a39d57817cfaab3a7 337 SUPERFAMILY SSF52418 97 332 3.3E-40 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CDC59_RS14390 ed31d37628ce1d2a39d57817cfaab3a7 337 Gene3D G3DSA:3.40.1030.10 103 336 1.0E-38 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CDC59_RS21855 5ccc44f374a0177da45b38fa17c7181e 247 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 47 236 1.1E-74 T 29-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CDC59_RS21855 5ccc44f374a0177da45b38fa17c7181e 247 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 39 241 40.346 T 29-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CDC59_RS21855 5ccc44f374a0177da45b38fa17c7181e 247 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 43 237 3.3E-68 T 29-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CDC59_RS21855 5ccc44f374a0177da45b38fa17c7181e 247 Gene3D G3DSA:3.90.870.10 35 247 1.4E-81 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CDC59_RS21855 5ccc44f374a0177da45b38fa17c7181e 247 SUPERFAMILY SSF55821 43 239 1.72E-75 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CDC59_RS17875 f89f2b5b1e3d6ef1a7eb5e4c16130389 1178 SMART SM00304 305 359 1.6E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CDC59_RS17875 f89f2b5b1e3d6ef1a7eb5e4c16130389 1178 Gene3D G3DSA:3.30.450.20 341 512 1.1E-18 T 29-03-2018 CDC59_RS17875 f89f2b5b1e3d6ef1a7eb5e4c16130389 1178 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 749 907 2.3E-38 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS17875 f89f2b5b1e3d6ef1a7eb5e4c16130389 1178 SMART SM00091 624 693 1.4E-6 T 29-03-2018 IPR000014 PAS domain CDC59_RS17875 f89f2b5b1e3d6ef1a7eb5e4c16130389 1178 SMART SM00091 366 440 3.5E-4 T 29-03-2018 IPR000014 PAS domain CDC59_RS17875 f89f2b5b1e3d6ef1a7eb5e4c16130389 1178 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 549 623 1.3E-7 T 29-03-2018 IPR000014 PAS domain CDC59_RS17875 f89f2b5b1e3d6ef1a7eb5e4c16130389 1178 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 621 748 2.2E-18 T 29-03-2018 IPR000014 PAS domain CDC59_RS17875 f89f2b5b1e3d6ef1a7eb5e4c16130389 1178 Gene3D G3DSA:3.30.450.20 624 749 4.8E-27 T 29-03-2018 CDC59_RS17875 f89f2b5b1e3d6ef1a7eb5e4c16130389 1178 SMART SM00086 574 616 1.2E-9 T 29-03-2018 IPR001610 PAC motif CDC59_RS17875 f89f2b5b1e3d6ef1a7eb5e4c16130389 1178 SMART SM00086 447 489 0.36 T 29-03-2018 IPR001610 PAC motif CDC59_RS17875 f89f2b5b1e3d6ef1a7eb5e4c16130389 1178 SMART SM00086 699 741 5.1E-7 T 29-03-2018 IPR001610 PAC motif CDC59_RS17875 f89f2b5b1e3d6ef1a7eb5e4c16130389 1178 Gene3D G3DSA:3.30.450.20 32 183 1.4E-14 T 29-03-2018 CDC59_RS17875 f89f2b5b1e3d6ef1a7eb5e4c16130389 1178 SMART SM00052 918 1165 2.6E-112 T 29-03-2018 IPR001633 EAL domain CDC59_RS17875 f89f2b5b1e3d6ef1a7eb5e4c16130389 1178 Pfam PF00563 EAL domain 925 1160 1.6E-70 T 29-03-2018 IPR001633 EAL domain CDC59_RS17875 f89f2b5b1e3d6ef1a7eb5e4c16130389 1178 SUPERFAMILY SSF55073 757 910 2.59E-44 T 29-03-2018 IPR029787 Nucleotide cyclase CDC59_RS17875 f89f2b5b1e3d6ef1a7eb5e4c16130389 1178 SUPERFAMILY SSF141868 923 1172 2.48E-88 T 29-03-2018 IPR001633 EAL domain CDC59_RS17875 f89f2b5b1e3d6ef1a7eb5e4c16130389 1178 Gene3D G3DSA:3.30.450.20 556 623 3.6E-14 T 29-03-2018 CDC59_RS17875 f89f2b5b1e3d6ef1a7eb5e4c16130389 1178 Pfam PF00990 Diguanylate cyclase, GGDEF domain 752 904 4.5E-41 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS17875 f89f2b5b1e3d6ef1a7eb5e4c16130389 1178 Pfam PF13426 PAS domain 643 740 7.7E-17 T 29-03-2018 IPR000014 PAS domain CDC59_RS17875 f89f2b5b1e3d6ef1a7eb5e4c16130389 1178 SUPERFAMILY SSF55785 356 487 1.64E-12 T 29-03-2018 IPR000014 PAS domain CDC59_RS17875 f89f2b5b1e3d6ef1a7eb5e4c16130389 1178 Pfam PF08447 PAS fold 525 609 3.3E-8 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 CDC59_RS17875 f89f2b5b1e3d6ef1a7eb5e4c16130389 1178 Pfam PF08447 PAS fold 418 481 1.6E-6 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 CDC59_RS17875 f89f2b5b1e3d6ef1a7eb5e4c16130389 1178 SUPERFAMILY SSF55785 631 741 1.93E-24 T 29-03-2018 IPR000014 PAS domain CDC59_RS17875 f89f2b5b1e3d6ef1a7eb5e4c16130389 1178 Gene3D G3DSA:3.30.450.20 513 555 1.2E-6 T 29-03-2018 CDC59_RS17875 f89f2b5b1e3d6ef1a7eb5e4c16130389 1178 Gene3D G3DSA:3.20.20.450 912 1178 1.8E-98 T 29-03-2018 IPR001633 EAL domain CDC59_RS17875 f89f2b5b1e3d6ef1a7eb5e4c16130389 1178 SMART SM00267 741 908 5.5E-52 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS17875 f89f2b5b1e3d6ef1a7eb5e4c16130389 1178 Gene3D G3DSA:3.30.70.270 750 911 4.0E-53 T 29-03-2018 CDC59_RS17875 f89f2b5b1e3d6ef1a7eb5e4c16130389 1178 SUPERFAMILY SSF55785 486 614 3.22E-15 T 29-03-2018 IPR000014 PAS domain CDC59_RS13450 3c6dd51bd789b1764bf1765e214168e5 352 SUPERFAMILY SSF54752 277 335 1.29E-23 T 29-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal CDC59_RS13450 3c6dd51bd789b1764bf1765e214168e5 352 SUPERFAMILY SSF52540 13 276 4.92E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS13450 3c6dd51bd789b1764bf1765e214168e5 352 PRINTS PR00142 RecA protein signature 252 281 3.0E-85 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CDC59_RS13450 3c6dd51bd789b1764bf1765e214168e5 352 PRINTS PR00142 RecA protein signature 136 165 3.0E-85 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CDC59_RS13450 3c6dd51bd789b1764bf1765e214168e5 352 PRINTS PR00142 RecA protein signature 102 131 3.0E-85 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CDC59_RS13450 3c6dd51bd789b1764bf1765e214168e5 352 PRINTS PR00142 RecA protein signature 174 203 3.0E-85 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CDC59_RS13450 3c6dd51bd789b1764bf1765e214168e5 352 PRINTS PR00142 RecA protein signature 219 247 3.0E-85 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CDC59_RS13450 3c6dd51bd789b1764bf1765e214168e5 352 PRINTS PR00142 RecA protein signature 306 323 3.0E-85 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CDC59_RS13450 3c6dd51bd789b1764bf1765e214168e5 352 Hamap MF_00268 Protein RecA [recA]. 14 338 52.054 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CDC59_RS13450 3c6dd51bd789b1764bf1765e214168e5 352 ProSitePatterns PS00321 recA signature. 222 230 - T 29-03-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 CDC59_RS13450 3c6dd51bd789b1764bf1765e214168e5 352 SMART SM00382 66 237 1.4E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS13450 3c6dd51bd789b1764bf1765e214168e5 352 Gene3D G3DSA:3.40.50.300 35 277 1.7E-46 T 29-03-2018 CDC59_RS13450 3c6dd51bd789b1764bf1765e214168e5 352 Gene3D G3DSA:3.30.250.10 278 335 4.5E-29 T 29-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal CDC59_RS13450 3c6dd51bd789b1764bf1765e214168e5 352 Pfam PF00154 recA bacterial DNA recombination protein 16 277 9.4E-142 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CDC59_RS13450 3c6dd51bd789b1764bf1765e214168e5 352 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 13 333 3.4E-173 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CDC59_RS17900 984c5b964fb59c992447d8f4f9d47c94 215 Gene3D G3DSA:3.40.630.20 1 215 5.1E-60 T 29-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like CDC59_RS17900 984c5b964fb59c992447d8f4f9d47c94 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 62 74 3.5E-39 T 29-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CDC59_RS17900 984c5b964fb59c992447d8f4f9d47c94 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 4 27 3.5E-39 T 29-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CDC59_RS17900 984c5b964fb59c992447d8f4f9d47c94 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 162 174 3.5E-39 T 29-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CDC59_RS17900 984c5b964fb59c992447d8f4f9d47c94 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 132 148 3.5E-39 T 29-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CDC59_RS17900 984c5b964fb59c992447d8f4f9d47c94 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 80 100 3.5E-39 T 29-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CDC59_RS17900 984c5b964fb59c992447d8f4f9d47c94 215 Pfam PF01470 Pyroglutamyl peptidase 3 202 2.9E-76 T 29-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like CDC59_RS17900 984c5b964fb59c992447d8f4f9d47c94 215 SUPERFAMILY SSF53182 1 215 5.23E-70 T 29-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like CDC59_RS17900 984c5b964fb59c992447d8f4f9d47c94 215 ProSitePatterns PS01334 Pyrrolidone-carboxylate peptidase cysteine active site. 130 144 - T 29-03-2018 IPR033694 Pyroglutamyl peptidase I, Cys active site CDC59_RS17900 984c5b964fb59c992447d8f4f9d47c94 215 TIGRFAM TIGR00504 pyro_pdase: pyroglutamyl-peptidase I 4 215 7.7E-85 T 29-03-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 CDC59_RS17900 984c5b964fb59c992447d8f4f9d47c94 215 Hamap MF_00417 Pyrrolidone-carboxylate peptidase [pcp]. 2 201 39.481 T 29-03-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 CDC59_RS17900 984c5b964fb59c992447d8f4f9d47c94 215 PIRSF PIRSF015592 1 213 2.5E-83 T 29-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CDC59_RS12445 e8f0481edcad88e4fd0d4d190fd15173 439 Gene3D G3DSA:3.40.50.300 5 231 5.6E-39 T 29-03-2018 CDC59_RS12445 e8f0481edcad88e4fd0d4d190fd15173 439 SUPERFAMILY SSF52540 9 231 6.27E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS12445 e8f0481edcad88e4fd0d4d190fd15173 439 Gene3D G3DSA:2.40.30.10 331 437 2.3E-27 T 29-03-2018 CDC59_RS12445 e8f0481edcad88e4fd0d4d190fd15173 439 Gene3D G3DSA:2.40.30.10 236 328 1.1E-18 T 29-03-2018 CDC59_RS12445 e8f0481edcad88e4fd0d4d190fd15173 439 SUPERFAMILY SSF50447 238 326 3.53E-18 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CDC59_RS12445 e8f0481edcad88e4fd0d4d190fd15173 439 PRINTS PR00315 GTP-binding elongation factor signature 72 80 4.3E-13 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDC59_RS12445 e8f0481edcad88e4fd0d4d190fd15173 439 PRINTS PR00315 GTP-binding elongation factor signature 153 162 4.3E-13 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDC59_RS12445 e8f0481edcad88e4fd0d4d190fd15173 439 PRINTS PR00315 GTP-binding elongation factor signature 108 119 4.3E-13 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDC59_RS12445 e8f0481edcad88e4fd0d4d190fd15173 439 PRINTS PR00315 GTP-binding elongation factor signature 92 102 4.3E-13 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDC59_RS12445 e8f0481edcad88e4fd0d4d190fd15173 439 PRINTS PR00315 GTP-binding elongation factor signature 12 25 4.3E-13 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDC59_RS12445 e8f0481edcad88e4fd0d4d190fd15173 439 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 11 435 1.8E-157 T 29-03-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 CDC59_RS12445 e8f0481edcad88e4fd0d4d190fd15173 439 Pfam PF00009 Elongation factor Tu GTP binding domain 11 208 6.4E-37 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDC59_RS12445 e8f0481edcad88e4fd0d4d190fd15173 439 Pfam PF03144 Elongation factor Tu domain 2 264 323 1.2E-7 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CDC59_RS12445 e8f0481edcad88e4fd0d4d190fd15173 439 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 65 80 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site CDC59_RS12445 e8f0481edcad88e4fd0d4d190fd15173 439 SUPERFAMILY SSF50465 334 436 7.19E-32 T 29-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal CDC59_RS02570 f89cf14f56580e6cc78500f272fcef16 233 SUPERFAMILY SSF53850 10 217 2.82E-66 T 29-03-2018 CDC59_RS02570 f89cf14f56580e6cc78500f272fcef16 233 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 11 196 2.9E-59 T 29-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 CDC59_RS02570 f89cf14f56580e6cc78500f272fcef16 233 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 10 220 56.094 T 29-03-2018 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 CDC59_RS02570 f89cf14f56580e6cc78500f272fcef16 233 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 155 176 - T 29-03-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 CDC59_RS02570 f89cf14f56580e6cc78500f272fcef16 233 Gene3D G3DSA:3.40.190.10 128 221 9.0E-21 T 29-03-2018 CDC59_RS02570 f89cf14f56580e6cc78500f272fcef16 233 Gene3D G3DSA:3.40.190.10 6 127 9.7E-40 T 29-03-2018 CDC59_RS02570 f89cf14f56580e6cc78500f272fcef16 233 Pfam PF01634 ATP phosphoribosyltransferase 60 214 7.7E-49 T 29-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 CDC59_RS04180 3a08165182db69ff8c0d87790ef8368e 357 Gene3D G3DSA:1.10.10.10 273 356 2.7E-34 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS04180 3a08165182db69ff8c0d87790ef8368e 357 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 275 354 3.5E-34 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CDC59_RS04180 3a08165182db69ff8c0d87790ef8368e 357 Pfam PF02805 Metal binding domain of Ada 14 77 7.9E-30 T 29-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 CDC59_RS04180 3a08165182db69ff8c0d87790ef8368e 357 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 325 331 - T 29-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CDC59_RS04180 3a08165182db69ff8c0d87790ef8368e 357 Pfam PF12833 Helix-turn-helix domain 111 188 1.9E-18 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CDC59_RS04180 3a08165182db69ff8c0d87790ef8368e 357 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 276 354 2.6E-32 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CDC59_RS04180 3a08165182db69ff8c0d87790ef8368e 357 SUPERFAMILY SSF46689 92 137 5.79E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS04180 3a08165182db69ff8c0d87790ef8368e 357 SMART SM00342 105 187 6.1E-17 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CDC59_RS04180 3a08165182db69ff8c0d87790ef8368e 357 PIRSF PIRSF000409 2 357 7.1E-139 T 29-03-2018 IPR016221 Bifunctional regulatory protein Ada CDC59_RS04180 3a08165182db69ff8c0d87790ef8368e 357 SUPERFAMILY SSF53155 194 273 5.49E-22 T 29-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CDC59_RS04180 3a08165182db69ff8c0d87790ef8368e 357 Gene3D G3DSA:1.10.10.60 144 186 0.0015 T 29-03-2018 CDC59_RS04180 3a08165182db69ff8c0d87790ef8368e 357 Gene3D G3DSA:1.10.10.60 82 143 3.0E-14 T 29-03-2018 CDC59_RS04180 3a08165182db69ff8c0d87790ef8368e 357 Gene3D G3DSA:3.30.160.70 187 272 1.2E-20 T 29-03-2018 CDC59_RS04180 3a08165182db69ff8c0d87790ef8368e 357 SUPERFAMILY SSF57884 9 94 6.15E-30 T 29-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 CDC59_RS04180 3a08165182db69ff8c0d87790ef8368e 357 SUPERFAMILY SSF46767 274 355 5.62E-31 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CDC59_RS04180 3a08165182db69ff8c0d87790ef8368e 357 Gene3D G3DSA:3.40.10.10 4 79 1.5E-24 T 29-03-2018 IPR035451 Ada-like domain CDC59_RS08015 273f7c05a2430825060444d579d99042 420 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 160 363 5.9E-22 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CDC59_RS08015 273f7c05a2430825060444d579d99042 420 Pfam PF07498 Rho termination factor, N-terminal domain 5 47 3.6E-16 T 29-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 CDC59_RS08015 273f7c05a2430825060444d579d99042 420 Pfam PF07497 Rho termination factor, RNA-binding domain 52 125 1.9E-30 T 29-03-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 CDC59_RS08015 273f7c05a2430825060444d579d99042 420 SUPERFAMILY SSF68912 1 46 1.22E-11 T 29-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 CDC59_RS08015 273f7c05a2430825060444d579d99042 420 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 419 242.643 T 29-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 CDC59_RS08015 273f7c05a2430825060444d579d99042 420 TIGRFAM TIGR00767 rho: transcription termination factor Rho 2 417 8.7E-210 T 29-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 CDC59_RS08015 273f7c05a2430825060444d579d99042 420 Gene3D G3DSA:3.40.50.300 129 419 1.1E-59 T 29-03-2018 CDC59_RS08015 273f7c05a2430825060444d579d99042 420 SMART SM00382 170 349 4.4E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS08015 273f7c05a2430825060444d579d99042 420 SMART SM00959 5 47 9.1E-18 T 29-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 CDC59_RS08015 273f7c05a2430825060444d579d99042 420 SMART SM00357 52 118 1.3E-17 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 CDC59_RS08015 273f7c05a2430825060444d579d99042 420 SUPERFAMILY SSF52540 90 371 9.55E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS08015 273f7c05a2430825060444d579d99042 420 Gene3D G3DSA:2.40.50.140 2 126 1.5E-45 T 29-03-2018 CDC59_RS08015 273f7c05a2430825060444d579d99042 420 SUPERFAMILY SSF50249 49 125 5.43E-28 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDC59_RS09705 b8cfe8b9bce9f980f5d1cb7839f9d7bb 512 Pfam PF00324 Amino acid permease 22 469 3.9E-132 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CDC59_RS09705 b8cfe8b9bce9f980f5d1cb7839f9d7bb 512 ProSitePatterns PS00218 Amino acid permeases signature. 47 78 - T 29-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CDC59_RS09705 b8cfe8b9bce9f980f5d1cb7839f9d7bb 512 PIRSF PIRSF006060 1 478 1.4E-76 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CDC59_RS19565 9e49121eff466b0fa8cdd3fb1cf38b22 172 Gene3D G3DSA:2.60.120.10 2 167 7.4E-59 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CDC59_RS19565 9e49121eff466b0fa8cdd3fb1cf38b22 172 Pfam PF06172 Cupin superfamily (DUF985) 8 145 1.2E-47 T 29-03-2018 IPR009327 Cupin domain of unknown function DUF985 CDC59_RS19565 9e49121eff466b0fa8cdd3fb1cf38b22 172 SUPERFAMILY SSF51182 4 166 1.87E-57 T 29-03-2018 IPR011051 RmlC-like cupin domain CDC59_RS16580 aad0eb3af52e2a569ab0009d46f2f7da 438 Gene3D G3DSA:3.20.20.80 126 437 3.7E-52 T 29-03-2018 CDC59_RS16580 aad0eb3af52e2a569ab0009d46f2f7da 438 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 139 408 1.1E-56 T 29-03-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 CDC59_RS16580 aad0eb3af52e2a569ab0009d46f2f7da 438 SUPERFAMILY SSF51445 129 430 1.15E-81 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CDC59_RS03000 ea4d1fe05925318a8d632850d520922a 509 SUPERFAMILY SSF53850 13 494 6.33E-132 T 29-03-2018 CDC59_RS03000 ea4d1fe05925318a8d632850d520922a 509 Gene3D G3DSA:3.40.190.10 162 285 6.7E-34 T 29-03-2018 CDC59_RS03000 ea4d1fe05925318a8d632850d520922a 509 Gene3D G3DSA:3.10.105.10 286 482 4.0E-55 T 29-03-2018 CDC59_RS03000 ea4d1fe05925318a8d632850d520922a 509 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 54 423 1.7E-91 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CDC59_RS03000 ea4d1fe05925318a8d632850d520922a 509 Gene3D G3DSA:3.90.76.10 20 161 4.9E-32 T 29-03-2018 CDC59_RS03000 ea4d1fe05925318a8d632850d520922a 509 PIRSF PIRSF002741 7 507 1.2E-103 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CDC59_RS16235 a9ce46c1c28d99985735afb6b59486e7 399 Gene3D G3DSA:1.20.1250.20 210 395 3.8E-16 T 29-03-2018 CDC59_RS16235 a9ce46c1c28d99985735afb6b59486e7 399 Gene3D G3DSA:1.20.120.540 130 209 0.0028 T 29-03-2018 IPR027378 Cyclic nucleotide-regulated ion channel, N-terminal domain Reactome: R-HSA-159418|Reactome: R-HSA-879518 CDC59_RS16235 a9ce46c1c28d99985735afb6b59486e7 399 Gene3D G3DSA:1.20.120.540 11 129 4.4E-11 T 29-03-2018 IPR027378 Cyclic nucleotide-regulated ion channel, N-terminal domain Reactome: R-HSA-159418|Reactome: R-HSA-879518 CDC59_RS16235 a9ce46c1c28d99985735afb6b59486e7 399 SUPERFAMILY SSF103473 20 392 4.19E-45 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS16235 a9ce46c1c28d99985735afb6b59486e7 399 Pfam PF07690 Major Facilitator Superfamily 31 188 2.1E-18 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDC59_RS13455 1259e1452746d2ae044ff1ac05820a4c 232 Pfam PF00072 Response regulator receiver domain 3 115 2.7E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS13455 1259e1452746d2ae044ff1ac05820a4c 232 SUPERFAMILY SSF52172 1 123 3.42E-36 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS13455 1259e1452746d2ae044ff1ac05820a4c 232 SMART SM00862 148 221 4.6E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDC59_RS13455 1259e1452746d2ae044ff1ac05820a4c 232 Gene3D G3DSA:3.40.50.2300 1 120 1.3E-33 T 29-03-2018 CDC59_RS13455 1259e1452746d2ae044ff1ac05820a4c 232 SUPERFAMILY SSF46894 123 222 4.54E-25 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CDC59_RS13455 1259e1452746d2ae044ff1ac05820a4c 232 Gene3D G3DSA:1.10.10.10 121 228 3.8E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS13455 1259e1452746d2ae044ff1ac05820a4c 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 221 1.1E-21 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDC59_RS13455 1259e1452746d2ae044ff1ac05820a4c 232 SMART SM00448 1 115 9.2E-38 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS10260 9bec29447d556659302362ccbd4864a3 168 Gene3D G3DSA:3.30.1330.50 1 163 3.8E-73 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CDC59_RS10260 9bec29447d556659302362ccbd4864a3 168 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 6 161 35.992 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CDC59_RS10260 9bec29447d556659302362ccbd4864a3 168 Pfam PF02542 YgbB family 6 159 1.2E-63 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CDC59_RS10260 9bec29447d556659302362ccbd4864a3 168 SUPERFAMILY SSF69765 4 162 1.44E-65 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CDC59_RS10260 9bec29447d556659302362ccbd4864a3 168 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 7 160 1.3E-65 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CDC59_RS10260 9bec29447d556659302362ccbd4864a3 168 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 40 55 - T 29-03-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CDC59_RS03225 7146c5b7d4b38cb2558eb2864b67ffc2 578 Gene3D G3DSA:3.30.450.90 146 300 6.1E-41 T 29-03-2018 CDC59_RS03225 7146c5b7d4b38cb2558eb2864b67ffc2 578 SUPERFAMILY SSF52540 169 574 4.23E-98 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS03225 7146c5b7d4b38cb2558eb2864b67ffc2 578 Gene3D G3DSA:3.40.50.300 301 578 1.5E-61 T 29-03-2018 CDC59_RS03225 7146c5b7d4b38cb2558eb2864b67ffc2 578 TIGRFAM TIGR02538 type_IV_pilB: type IV-A pilus assembly ATPase PilB 3 577 3.2E-230 T 29-03-2018 IPR013374 ATPase, type IV, pilus assembly, PilB GO:0005524|GO:0008565|GO:0009297 CDC59_RS03225 7146c5b7d4b38cb2558eb2864b67ffc2 578 Pfam PF00437 Type II/IV secretion system protein 187 467 3.1E-84 T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CDC59_RS03225 7146c5b7d4b38cb2558eb2864b67ffc2 578 SMART SM00382 328 449 0.0079 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS03225 7146c5b7d4b38cb2558eb2864b67ffc2 578 SUPERFAMILY SSF160246 2 134 2.41E-23 T 29-03-2018 CDC59_RS03225 7146c5b7d4b38cb2558eb2864b67ffc2 578 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 36 133 3.3E-11 T 29-03-2018 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 CDC59_RS03225 7146c5b7d4b38cb2558eb2864b67ffc2 578 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 395 409 - T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CDC59_RS10320 bded23ab5284d9febb01501d6f19fa5e 246 SUPERFAMILY SSF51735 3 245 1.89E-75 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS10320 bded23ab5284d9febb01501d6f19fa5e 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CDC59_RS10320 bded23ab5284d9febb01501d6f19fa5e 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 189 2.3E-4 T 29-03-2018 CDC59_RS10320 bded23ab5284d9febb01501d6f19fa5e 246 Pfam PF00106 short chain dehydrogenase 5 197 3.3E-63 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS10320 bded23ab5284d9febb01501d6f19fa5e 246 TIGRFAM TIGR01829 AcAcCoA_reduct: acetoacetyl-CoA reductase 4 245 1.7E-122 T 29-03-2018 IPR011283 Acetoacetyl-CoA reductase GO:0005737|GO:0018454|GO:0042619|GO:0055114 KEGG: 00630+1.1.1.36|KEGG: 00650+1.1.1.36|MetaCyc: PWY-5676|MetaCyc: PWY-5741|MetaCyc: PWY-7216 CDC59_RS10320 bded23ab5284d9febb01501d6f19fa5e 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 1.7E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS10320 bded23ab5284d9febb01501d6f19fa5e 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.7E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS10320 bded23ab5284d9febb01501d6f19fa5e 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.7E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS10320 bded23ab5284d9febb01501d6f19fa5e 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 1.7E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS10320 bded23ab5284d9febb01501d6f19fa5e 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.7E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS10320 bded23ab5284d9febb01501d6f19fa5e 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.7E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS10320 bded23ab5284d9febb01501d6f19fa5e 246 Gene3D G3DSA:3.40.50.720 3 245 3.0E-69 T 29-03-2018 CDC59_RS10320 bded23ab5284d9febb01501d6f19fa5e 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 3.6E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS10320 bded23ab5284d9febb01501d6f19fa5e 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 3.6E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS10320 bded23ab5284d9febb01501d6f19fa5e 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 3.6E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS11450 21ef4c27730ce9b8a9ccfe0d1e83372b 469 PRINTS PR00415 Aconitase family signature 108 116 5.2E-47 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS11450 21ef4c27730ce9b8a9ccfe0d1e83372b 469 PRINTS PR00415 Aconitase family signature 195 208 5.2E-47 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS11450 21ef4c27730ce9b8a9ccfe0d1e83372b 469 PRINTS PR00415 Aconitase family signature 119 132 5.2E-47 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS11450 21ef4c27730ce9b8a9ccfe0d1e83372b 469 PRINTS PR00415 Aconitase family signature 343 354 5.2E-47 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS11450 21ef4c27730ce9b8a9ccfe0d1e83372b 469 PRINTS PR00415 Aconitase family signature 402 415 5.2E-47 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS11450 21ef4c27730ce9b8a9ccfe0d1e83372b 469 PRINTS PR00415 Aconitase family signature 286 300 5.2E-47 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS11450 21ef4c27730ce9b8a9ccfe0d1e83372b 469 PRINTS PR00415 Aconitase family signature 209 222 5.2E-47 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS11450 21ef4c27730ce9b8a9ccfe0d1e83372b 469 PRINTS PR00415 Aconitase family signature 82 95 5.2E-47 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS11450 21ef4c27730ce9b8a9ccfe0d1e83372b 469 PRINTS PR00415 Aconitase family signature 133 148 5.2E-47 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS11450 21ef4c27730ce9b8a9ccfe0d1e83372b 469 Pfam PF00330 Aconitase family (aconitate hydratase) 7 460 3.2E-157 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS11450 21ef4c27730ce9b8a9ccfe0d1e83372b 469 ProSitePatterns PS01244 Aconitase family signature 2. 402 415 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CDC59_RS11450 21ef4c27730ce9b8a9ccfe0d1e83372b 469 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 1 469 60.242 T 29-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 CDC59_RS11450 21ef4c27730ce9b8a9ccfe0d1e83372b 469 SUPERFAMILY SSF53732 2 468 4.32E-164 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS11450 21ef4c27730ce9b8a9ccfe0d1e83372b 469 ProSitePatterns PS00450 Aconitase family signature 1. 339 355 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CDC59_RS11450 21ef4c27730ce9b8a9ccfe0d1e83372b 469 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 1 468 2.9E-236 T 29-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 CDC59_RS11450 21ef4c27730ce9b8a9ccfe0d1e83372b 469 Gene3D G3DSA:3.40.1060.10 154 288 1.3E-41 T 29-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS11450 21ef4c27730ce9b8a9ccfe0d1e83372b 469 Gene3D G3DSA:3.30.499.10 1 153 3.5E-39 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS11450 21ef4c27730ce9b8a9ccfe0d1e83372b 469 Gene3D G3DSA:3.30.499.10 292 469 1.6E-51 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS21650 6fdbe49866d31cffccd8d7d0df11df00 363 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 310 322 7.9E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS21650 6fdbe49866d31cffccd8d7d0df11df00 363 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 280 294 7.9E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS21650 6fdbe49866d31cffccd8d7d0df11df00 363 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 294 310 7.9E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS21650 6fdbe49866d31cffccd8d7d0df11df00 363 SMART SM00421 277 334 7.6E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS21650 6fdbe49866d31cffccd8d7d0df11df00 363 Pfam PF00196 Bacterial regulatory proteins, luxR family 280 329 1.0E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS21650 6fdbe49866d31cffccd8d7d0df11df00 363 Gene3D G3DSA:3.30.450.80 64 164 1.5E-5 T 29-03-2018 CDC59_RS21650 6fdbe49866d31cffccd8d7d0df11df00 363 SUPERFAMILY SSF46894 271 337 2.11E-15 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CDC59_RS21650 6fdbe49866d31cffccd8d7d0df11df00 363 Gene3D G3DSA:1.10.10.10 165 339 4.3E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS13245 03bf0ecfd32d2782ef3322de538e4e03 173 Pfam PF01047 MarR family 60 117 6.7E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS13245 03bf0ecfd32d2782ef3322de538e4e03 173 PRINTS PR00598 Bacterial regulatory protein MarR family signature 113 129 5.0E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS13245 03bf0ecfd32d2782ef3322de538e4e03 173 PRINTS PR00598 Bacterial regulatory protein MarR family signature 77 93 5.0E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS13245 03bf0ecfd32d2782ef3322de538e4e03 173 PRINTS PR00598 Bacterial regulatory protein MarR family signature 143 163 5.0E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS13245 03bf0ecfd32d2782ef3322de538e4e03 173 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 109 5.0E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS13245 03bf0ecfd32d2782ef3322de538e4e03 173 Gene3D G3DSA:1.10.10.10 20 169 2.0E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS13245 03bf0ecfd32d2782ef3322de538e4e03 173 SMART SM00347 53 153 9.2E-18 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS13245 03bf0ecfd32d2782ef3322de538e4e03 173 SUPERFAMILY SSF46785 26 165 1.93E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS02830 77a204808538c7735f917c1ca9f06e2f 435 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 106 129 - T 29-03-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CDC59_RS02830 77a204808538c7735f917c1ca9f06e2f 435 SUPERFAMILY SSF69075 329 428 1.57E-29 T 29-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CDC59_RS02830 77a204808538c7735f917c1ca9f06e2f 435 PIRSF PIRSF000445 1 435 6.4E-148 T 29-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CDC59_RS02830 77a204808538c7735f917c1ca9f06e2f 435 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 4 427 1.7E-124 T 29-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CDC59_RS02830 77a204808538c7735f917c1ca9f06e2f 435 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 332 427 1.8E-27 T 29-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CDC59_RS02830 77a204808538c7735f917c1ca9f06e2f 435 SUPERFAMILY SSF69742 1 165 2.09E-45 T 29-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CDC59_RS02830 77a204808538c7735f917c1ca9f06e2f 435 SUPERFAMILY SSF51735 170 324 1.95E-34 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS02830 77a204808538c7735f917c1ca9f06e2f 435 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 430 29.403 T 29-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CDC59_RS02830 77a204808538c7735f917c1ca9f06e2f 435 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 6 163 1.7E-47 T 29-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CDC59_RS02830 77a204808538c7735f917c1ca9f06e2f 435 Gene3D G3DSA:3.40.50.720 168 325 1.1E-24 T 29-03-2018 CDC59_RS02830 77a204808538c7735f917c1ca9f06e2f 435 Gene3D G3DSA:1.10.1200.70 344 428 6.7E-26 T 29-03-2018 CDC59_RS02830 77a204808538c7735f917c1ca9f06e2f 435 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 179 317 1.0E-44 T 29-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase CDC59_RS13645 11d6cc716415c7bd208f9ad45e9e9f31 338 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 4 332 4.4E-119 T 29-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 CDC59_RS13645 11d6cc716415c7bd208f9ad45e9e9f31 338 SUPERFAMILY SSF53659 4 334 9.49E-100 T 29-03-2018 CDC59_RS13645 11d6cc716415c7bd208f9ad45e9e9f31 338 Gene3D G3DSA:3.40.718.10 1 335 6.6E-124 T 29-03-2018 CDC59_RS13645 11d6cc716415c7bd208f9ad45e9e9f31 338 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 40 328 5.0E-104 T 29-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 CDC59_RS13645 11d6cc716415c7bd208f9ad45e9e9f31 338 Hamap MF_00536 4-hydroxythreonine-4-phosphate dehydrogenase [pdxA]. 1 332 35.031 T 29-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 CDC59_RS17540 4c44cf78de9b267acd6de9e2dfe2c0d6 301 Gene3D G3DSA:1.10.10.10 3 86 3.1E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS17540 4c44cf78de9b267acd6de9e2dfe2c0d6 301 Gene3D G3DSA:3.40.190.10 91 178 1.9E-12 T 29-03-2018 CDC59_RS17540 4c44cf78de9b267acd6de9e2dfe2c0d6 301 Gene3D G3DSA:3.40.190.10 179 267 3.6E-32 T 29-03-2018 CDC59_RS17540 4c44cf78de9b267acd6de9e2dfe2c0d6 301 SUPERFAMILY SSF53850 92 298 1.24E-47 T 29-03-2018 CDC59_RS17540 4c44cf78de9b267acd6de9e2dfe2c0d6 301 Pfam PF03466 LysR substrate binding domain 90 296 5.7E-48 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS17540 4c44cf78de9b267acd6de9e2dfe2c0d6 301 SUPERFAMILY SSF46785 4 114 1.52E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS17540 4c44cf78de9b267acd6de9e2dfe2c0d6 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 1.3E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS16315 c6bb70c0a3effb4f0b14d343d8e0118e 217 SUPERFAMILY SSF46689 20 98 7.7E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS16315 c6bb70c0a3effb4f0b14d343d8e0118e 217 Gene3D G3DSA:1.10.10.60 21 77 1.6E-16 T 29-03-2018 CDC59_RS16315 c6bb70c0a3effb4f0b14d343d8e0118e 217 Pfam PF00440 Bacterial regulatory proteins, tetR family 32 77 1.1E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDC59_RS16315 c6bb70c0a3effb4f0b14d343d8e0118e 217 SUPERFAMILY SSF48498 100 192 1.19E-13 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CDC59_RS16315 c6bb70c0a3effb4f0b14d343d8e0118e 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 45 2.6E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDC59_RS16315 c6bb70c0a3effb4f0b14d343d8e0118e 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 53 76 2.6E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDC59_RS16315 c6bb70c0a3effb4f0b14d343d8e0118e 217 Gene3D G3DSA:1.10.357.10 78 208 1.1E-25 T 29-03-2018 CDC59_RS22035 c6fb937a798022d24b98cc17c71e7d89 411 Gene3D G3DSA:3.50.50.60 248 329 2.1E-7 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS22035 c6fb937a798022d24b98cc17c71e7d89 411 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 105 123 8.5E-22 T 29-03-2018 CDC59_RS22035 c6fb937a798022d24b98cc17c71e7d89 411 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 282 8.5E-22 T 29-03-2018 CDC59_RS22035 c6fb937a798022d24b98cc17c71e7d89 411 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 150 168 8.5E-22 T 29-03-2018 CDC59_RS22035 c6fb937a798022d24b98cc17c71e7d89 411 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 8.5E-22 T 29-03-2018 CDC59_RS22035 c6fb937a798022d24b98cc17c71e7d89 411 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 235 251 8.5E-22 T 29-03-2018 CDC59_RS22035 c6fb937a798022d24b98cc17c71e7d89 411 Gene3D G3DSA:3.50.50.60 105 244 2.3E-34 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS22035 c6fb937a798022d24b98cc17c71e7d89 411 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 236 250 9.5E-14 T 29-03-2018 CDC59_RS22035 c6fb937a798022d24b98cc17c71e7d89 411 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 150 175 9.5E-14 T 29-03-2018 CDC59_RS22035 c6fb937a798022d24b98cc17c71e7d89 411 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 8 30 9.5E-14 T 29-03-2018 CDC59_RS22035 c6fb937a798022d24b98cc17c71e7d89 411 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 275 282 9.5E-14 T 29-03-2018 CDC59_RS22035 c6fb937a798022d24b98cc17c71e7d89 411 SUPERFAMILY SSF51905 145 310 1.05E-29 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS22035 c6fb937a798022d24b98cc17c71e7d89 411 Gene3D G3DSA:3.50.50.60 2 104 1.1E-11 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS22035 c6fb937a798022d24b98cc17c71e7d89 411 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 283 7.5E-57 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS22035 c6fb937a798022d24b98cc17c71e7d89 411 SUPERFAMILY SSF51905 7 194 2.88E-46 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS12380 9c51e704d2db48512bc4599e0f767948 156 Pfam PF01878 EVE domain 4 148 9.5E-52 T 29-03-2018 IPR002740 EVE domain CDC59_RS12380 9c51e704d2db48512bc4599e0f767948 156 Gene3D G3DSA:3.10.590.10 2 154 5.1E-56 T 29-03-2018 CDC59_RS12380 9c51e704d2db48512bc4599e0f767948 156 SUPERFAMILY SSF88697 3 149 4.26E-58 T 29-03-2018 IPR015947 PUA-like domain CDC59_RS07205 b7eed95ca6615b9d59228081248bc9c9 404 Hamap MF_00570 Nicotinate phosphoribosyltransferase [pncB]. 14 404 45.686 T 29-03-2018 IPR006406 Nicotinate phosphoribosyltransferase GO:0004516|GO:0019357 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CDC59_RS07205 b7eed95ca6615b9d59228081248bc9c9 404 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 178 403 2.9E-72 T 29-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 CDC59_RS07205 b7eed95ca6615b9d59228081248bc9c9 404 PIRSF PIRSF000484 12 398 2.3E-67 T 29-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 CDC59_RS07205 b7eed95ca6615b9d59228081248bc9c9 404 SUPERFAMILY SSF54675 14 152 6.36E-45 T 29-03-2018 CDC59_RS07205 b7eed95ca6615b9d59228081248bc9c9 404 Gene3D G3DSA:3.20.140.10 12 404 1.5E-100 T 29-03-2018 CDC59_RS07205 b7eed95ca6615b9d59228081248bc9c9 404 SUPERFAMILY SSF51690 133 403 5.49E-91 T 29-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CDC59_RS07205 b7eed95ca6615b9d59228081248bc9c9 404 TIGRFAM TIGR01514 NAPRTase: nicotinate phosphoribosyltransferase 17 402 1.9E-144 T 29-03-2018 IPR006406 Nicotinate phosphoribosyltransferase GO:0004516|GO:0019357 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CDC59_RS03660 f00ee08356fa7e47abf88f25eac2cb33 510 Gene3D G3DSA:1.20.1250.20 9 205 1.3E-26 T 29-03-2018 CDC59_RS03660 f00ee08356fa7e47abf88f25eac2cb33 510 Gene3D G3DSA:1.20.1250.20 255 504 1.6E-19 T 29-03-2018 CDC59_RS03660 f00ee08356fa7e47abf88f25eac2cb33 510 SUPERFAMILY SSF103473 11 196 2.22E-54 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS03660 f00ee08356fa7e47abf88f25eac2cb33 510 SUPERFAMILY SSF103473 251 422 2.22E-54 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS03660 f00ee08356fa7e47abf88f25eac2cb33 510 SUPERFAMILY SSF103473 474 501 2.22E-54 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS03660 f00ee08356fa7e47abf88f25eac2cb33 510 Pfam PF07690 Major Facilitator Superfamily 21 412 1.7E-45 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDC59_RS03660 f00ee08356fa7e47abf88f25eac2cb33 510 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 20 497 3.3E-101 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CDC59_RS15045 894f33012b7489943188685c222c88f0 946 Gene3D G3DSA:1.25.40.20 173 448 8.2E-29 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CDC59_RS15045 894f33012b7489943188685c222c88f0 946 SUPERFAMILY SSF48403 403 436 3.22E-38 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CDC59_RS15045 894f33012b7489943188685c222c88f0 946 SUPERFAMILY SSF48403 70 256 3.22E-38 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CDC59_RS15045 894f33012b7489943188685c222c88f0 946 SMART SM00248 234 264 0.25 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CDC59_RS15045 894f33012b7489943188685c222c88f0 946 SMART SM00248 200 230 3.1 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CDC59_RS15045 894f33012b7489943188685c222c88f0 946 SMART SM00248 96 125 14.0 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CDC59_RS15045 894f33012b7489943188685c222c88f0 946 SMART SM00248 414 444 550.0 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CDC59_RS15045 894f33012b7489943188685c222c88f0 946 SMART SM00248 132 162 0.2 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CDC59_RS15045 894f33012b7489943188685c222c88f0 946 SMART SM00248 166 196 6.5E-4 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CDC59_RS15045 894f33012b7489943188685c222c88f0 946 Gene3D G3DSA:1.25.40.20 61 172 3.3E-24 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CDC59_RS15045 894f33012b7489943188685c222c88f0 946 Pfam PF12796 Ankyrin repeats (3 copies) 91 159 1.2E-8 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CDC59_RS15045 894f33012b7489943188685c222c88f0 946 Pfam PF12796 Ankyrin repeats (3 copies) 165 231 1.7E-9 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CDC59_RS03165 46417012f2ba32a5241a00e8f1f4f15d 305 TIGRFAM TIGR00325 lpxC: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 2 296 6.2E-124 T 29-03-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CDC59_RS03165 46417012f2ba32a5241a00e8f1f4f15d 305 Gene3D G3DSA:3.30.1700.10 128 298 5.0E-67 T 29-03-2018 IPR011334 UDP-3-O-acyl N-acetylglucosamine deacetylase, C-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CDC59_RS03165 46417012f2ba32a5241a00e8f1f4f15d 305 Gene3D G3DSA:3.30.230.20 1 127 4.3E-49 T 29-03-2018 IPR015870 UDP-3-O-acyl N-acetylglucosamine deacetylase, N-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CDC59_RS03165 46417012f2ba32a5241a00e8f1f4f15d 305 SUPERFAMILY SSF54211 133 277 2.96E-51 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CDC59_RS03165 46417012f2ba32a5241a00e8f1f4f15d 305 Hamap MF_00388 UDP-3-O-acyl-N-acetylglucosamine deacetylase [lpxC]. 2 279 47.108 T 29-03-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CDC59_RS03165 46417012f2ba32a5241a00e8f1f4f15d 305 Pfam PF03331 UDP-3-O-acyl N-acetylglycosamine deacetylase 4 275 1.9E-107 T 29-03-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CDC59_RS03165 46417012f2ba32a5241a00e8f1f4f15d 305 SUPERFAMILY SSF54211 3 124 1.06E-41 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CDC59_RS20805 53dd81df2990cb7527d0018f7f5f70fe 611 Pfam PF07940 Heparinase II/III-like protein 388 600 2.3E-34 T 29-03-2018 IPR012480 Heparinase II/III-like GO:0016829 CDC59_RS20805 53dd81df2990cb7527d0018f7f5f70fe 611 Gene3D G3DSA:1.50.10.100 64 365 6.8E-20 T 29-03-2018 CDC59_RS20805 53dd81df2990cb7527d0018f7f5f70fe 611 SUPERFAMILY SSF48230 80 354 1.28E-25 T 29-03-2018 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 CDC59_RS20805 53dd81df2990cb7527d0018f7f5f70fe 611 Pfam PF16889 Heparinase II/III N-terminus 150 318 1.3E-6 T 29-03-2018 IPR031680 Heparin-sulfate lyase, N-terminal MetaCyc: PWY-7651 CDC59_RS15970 c01dd99c73906259f8d21023460cff62 223 PIRSF PIRSF009320 3 223 6.3E-39 T 29-03-2018 CDC59_RS15970 c01dd99c73906259f8d21023460cff62 223 SUPERFAMILY SSF52540 3 218 9.13E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS15970 c01dd99c73906259f8d21023460cff62 223 Gene3D G3DSA:3.40.50.300 4 223 2.0E-33 T 29-03-2018 CDC59_RS15970 c01dd99c73906259f8d21023460cff62 223 Pfam PF13614 AAA domain 4 49 4.1E-13 T 29-03-2018 IPR025669 AAA domain CDC59_RS15970 c01dd99c73906259f8d21023460cff62 223 Pfam PF13614 AAA domain 68 135 1.1E-7 T 29-03-2018 IPR025669 AAA domain CDC59_RS16830 20c73b08ec52c6d3808130ca2d80dcdd 305 Gene3D G3DSA:1.10.10.10 3 84 2.9E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS16830 20c73b08ec52c6d3808130ca2d80dcdd 305 Gene3D G3DSA:3.40.190.10 179 264 3.4E-21 T 29-03-2018 CDC59_RS16830 20c73b08ec52c6d3808130ca2d80dcdd 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 2.4E-14 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS16830 20c73b08ec52c6d3808130ca2d80dcdd 305 SUPERFAMILY SSF46785 3 112 1.81E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS16830 20c73b08ec52c6d3808130ca2d80dcdd 305 Gene3D G3DSA:3.40.190.10 89 178 1.1E-14 T 29-03-2018 CDC59_RS16830 20c73b08ec52c6d3808130ca2d80dcdd 305 Pfam PF03466 LysR substrate binding domain 88 296 1.1E-41 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS16830 20c73b08ec52c6d3808130ca2d80dcdd 305 SUPERFAMILY SSF53850 88 298 3.26E-45 T 29-03-2018 CDC59_RS23390 683c944a677d4925f05f7fc02ea97987 130 Gene3D G3DSA:3.20.10.10 52 130 3.2E-4 T 29-03-2018 CDC59_RS12915 8ac0dd480314be66f88761cc26d81fdf 468 Gene3D G3DSA:3.40.50.261 111 402 4.6E-5 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CDC59_RS12915 8ac0dd480314be66f88761cc26d81fdf 468 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 27 459 27.74 T 29-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 CDC59_RS12915 8ac0dd480314be66f88761cc26d81fdf 468 Gene3D G3DSA:2.40.50.140 36 110 6.0E-6 T 29-03-2018 CDC59_RS12915 8ac0dd480314be66f88761cc26d81fdf 468 Pfam PF13742 OB-fold nucleic acid binding domain 30 122 1.5E-28 T 29-03-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 CDC59_RS12915 8ac0dd480314be66f88761cc26d81fdf 468 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 31 377 7.6E-129 T 29-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 CDC59_RS12915 8ac0dd480314be66f88761cc26d81fdf 468 Pfam PF02601 Exonuclease VII, large subunit 146 455 1.7E-93 T 29-03-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 CDC59_RS21735 8a03c5fdc6746e305d663ec8a468a557 234 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 45 1.3E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDC59_RS21735 8a03c5fdc6746e305d663ec8a468a557 234 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 53 76 1.3E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDC59_RS21735 8a03c5fdc6746e305d663ec8a468a557 234 Gene3D G3DSA:1.10.357.10 78 215 1.9E-12 T 29-03-2018 CDC59_RS21735 8a03c5fdc6746e305d663ec8a468a557 234 SUPERFAMILY SSF46689 19 94 1.31E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS21735 8a03c5fdc6746e305d663ec8a468a557 234 SUPERFAMILY SSF48498 101 186 2.74E-7 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CDC59_RS21735 8a03c5fdc6746e305d663ec8a468a557 234 Pfam PF00440 Bacterial regulatory proteins, tetR family 32 76 1.8E-14 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDC59_RS21735 8a03c5fdc6746e305d663ec8a468a557 234 Gene3D G3DSA:1.10.10.60 1 77 2.8E-18 T 29-03-2018 CDC59_RS18365 b1a5c82b653af0e9bb67d19496c8fb7e 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 209 7.8E-20 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS18365 b1a5c82b653af0e9bb67d19496c8fb7e 217 Pfam PF00072 Response regulator receiver domain 5 115 3.4E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS18365 b1a5c82b653af0e9bb67d19496c8fb7e 217 SUPERFAMILY SSF46894 143 215 4.08E-21 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CDC59_RS18365 b1a5c82b653af0e9bb67d19496c8fb7e 217 Gene3D G3DSA:3.40.50.2300 2 127 2.0E-35 T 29-03-2018 CDC59_RS18365 b1a5c82b653af0e9bb67d19496c8fb7e 217 SUPERFAMILY SSF52172 2 131 1.57E-33 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS18365 b1a5c82b653af0e9bb67d19496c8fb7e 217 ProSitePatterns PS00622 LuxR-type HTH domain signature. 169 196 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS18365 b1a5c82b653af0e9bb67d19496c8fb7e 217 Gene3D G3DSA:1.10.10.10 128 217 8.1E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS18365 b1a5c82b653af0e9bb67d19496c8fb7e 217 SMART SM00448 3 116 2.7E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS18365 b1a5c82b653af0e9bb67d19496c8fb7e 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 4.7E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS18365 b1a5c82b653af0e9bb67d19496c8fb7e 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 4.7E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS18365 b1a5c82b653af0e9bb67d19496c8fb7e 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 4.7E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS18365 b1a5c82b653af0e9bb67d19496c8fb7e 217 SMART SM00421 152 209 6.4E-22 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS08660 6253dec2d16361573e4024b76f6844e9 331 TIGRFAM TIGR00520 asnASE_II: L-asparaginase, type II 2 319 3.4E-96 T 29-03-2018 IPR004550 L-asparaginase, type II GO:0004067|GO:0006528 CDC59_RS08660 6253dec2d16361573e4024b76f6844e9 331 SMART SM00870 6 322 1.2E-124 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CDC59_RS08660 6253dec2d16361573e4024b76f6844e9 331 SUPERFAMILY SSF53774 5 321 4.58E-89 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CDC59_RS08660 6253dec2d16361573e4024b76f6844e9 331 Pfam PF00710 Asparaginase, N-terminal 7 200 1.8E-57 T 29-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 CDC59_RS08660 6253dec2d16361573e4024b76f6844e9 331 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 9 17 - T 29-03-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 CDC59_RS08660 6253dec2d16361573e4024b76f6844e9 331 Gene3D G3DSA:3.40.50.40 219 331 4.4E-25 T 29-03-2018 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 CDC59_RS08660 6253dec2d16361573e4024b76f6844e9 331 PRINTS PR00139 Asparaginase/glutaminase family signature 266 284 2.2E-22 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CDC59_RS08660 6253dec2d16361573e4024b76f6844e9 331 PRINTS PR00139 Asparaginase/glutaminase family signature 88 106 2.2E-22 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CDC59_RS08660 6253dec2d16361573e4024b76f6844e9 331 PRINTS PR00139 Asparaginase/glutaminase family signature 7 18 2.2E-22 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CDC59_RS08660 6253dec2d16361573e4024b76f6844e9 331 PIRSF PIRSF001220 1 330 1.5E-80 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CDC59_RS08660 6253dec2d16361573e4024b76f6844e9 331 Gene3D G3DSA:3.40.50.1170 2 208 6.5E-52 T 29-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 CDC59_RS08660 6253dec2d16361573e4024b76f6844e9 331 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 89 99 - T 29-03-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 CDC59_RS08660 6253dec2d16361573e4024b76f6844e9 331 PIRSF PIRSF500176 3 329 7.0E-73 T 29-03-2018 CDC59_RS13640 a3a1724cbd3ff375525f1c82332e5b92 281 SMART SM00650 28 198 2.9E-75 T 29-03-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 CDC59_RS13640 a3a1724cbd3ff375525f1c82332e5b92 281 Pfam PF00398 Ribosomal RNA adenine dimethylase 12 265 1.7E-57 T 29-03-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm CDC59_RS13640 a3a1724cbd3ff375525f1c82332e5b92 281 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 44 71 - T 29-03-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 CDC59_RS13640 a3a1724cbd3ff375525f1c82332e5b92 281 Gene3D G3DSA:3.40.50.150 2 205 1.0E-51 T 29-03-2018 CDC59_RS13640 a3a1724cbd3ff375525f1c82332e5b92 281 Gene3D G3DSA:1.10.8.100 207 271 4.3E-14 T 29-03-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 CDC59_RS13640 a3a1724cbd3ff375525f1c82332e5b92 281 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 13 266 2.4E-77 T 29-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 CDC59_RS13640 a3a1724cbd3ff375525f1c82332e5b92 281 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 12 267 54.393 T 29-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 CDC59_RS13640 a3a1724cbd3ff375525f1c82332e5b92 281 SUPERFAMILY SSF53335 9 266 4.22E-71 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS17915 f8eb2b2aff82ca90f2e25e2dd32f10f9 537 PIRSF PIRSF006281 2 529 3.3E-196 T 29-03-2018 IPR014438 Glucan biosynthesis, periplasmic, MdoG/D CDC59_RS17915 f8eb2b2aff82ca90f2e25e2dd32f10f9 537 Pfam PF04349 Periplasmic glucan biosynthesis protein, MdoG 40 525 1.6E-188 T 29-03-2018 IPR007444 Glucan biosynthesis, periplasmic, MdoG C-terminal GO:0016051|GO:0042597 CDC59_RS17915 f8eb2b2aff82ca90f2e25e2dd32f10f9 537 Gene3D G3DSA:2.60.40.10 419 529 3.9E-31 T 29-03-2018 IPR013783 Immunoglobulin-like fold CDC59_RS17915 f8eb2b2aff82ca90f2e25e2dd32f10f9 537 SUPERFAMILY SSF81296 419 527 1.54E-29 T 29-03-2018 IPR014756 Immunoglobulin E-set CDC59_RS17915 f8eb2b2aff82ca90f2e25e2dd32f10f9 537 SUPERFAMILY SSF74650 40 418 4.71E-146 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CDC59_RS17915 f8eb2b2aff82ca90f2e25e2dd32f10f9 537 Gene3D G3DSA:2.70.98.10 40 415 5.3E-165 T 29-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CDC59_RS12455 365219611e6cdeac003ceaa6cd234d13 267 PIRSF PIRSF000857 24 265 1.9E-77 T 29-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 CDC59_RS12455 365219611e6cdeac003ceaa6cd234d13 267 SUPERFAMILY SSF52402 35 222 4.95E-41 T 29-03-2018 CDC59_RS12455 365219611e6cdeac003ceaa6cd234d13 267 TIGRFAM TIGR02055 APS_reductase: adenylylsulfate reductase, thioredoxin dependent 61 258 6.8E-80 T 29-03-2018 IPR011798 Adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019344|GO:0055114 KEGG: 00920+1.8.4.8 CDC59_RS12455 365219611e6cdeac003ceaa6cd234d13 267 Gene3D G3DSA:3.40.50.620 41 267 1.6E-37 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDC59_RS12455 365219611e6cdeac003ceaa6cd234d13 267 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 64 234 3.3E-37 T 29-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 CDC59_RS09120 6853a16d48da6a8d73796db879157c51 813 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 734 805 3.3E-13 T 29-03-2018 IPR001357 BRCT domain CDC59_RS09120 6853a16d48da6a8d73796db879157c51 813 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 20 633 1.3E-199 T 29-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CDC59_RS09120 6853a16d48da6a8d73796db879157c51 813 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 348 363 - T 29-03-2018 IPR033136 NAD-dependent DNA ligase, conserved site CDC59_RS09120 6853a16d48da6a8d73796db879157c51 813 Gene3D G3DSA:2.40.50.140 334 407 2.2E-33 T 29-03-2018 CDC59_RS09120 6853a16d48da6a8d73796db879157c51 813 Pfam PF12826 Helix-hairpin-helix motif 559 621 1.9E-17 T 29-03-2018 CDC59_RS09120 6853a16d48da6a8d73796db879157c51 813 SMART SM00532 12 480 2.6E-245 T 29-03-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 CDC59_RS09120 6853a16d48da6a8d73796db879157c51 813 Hamap MF_01588 DNA ligase [ligA]. 11 805 57.661 T 29-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CDC59_RS09120 6853a16d48da6a8d73796db879157c51 813 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 440 466 1.5E-11 T 29-03-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 CDC59_RS09120 6853a16d48da6a8d73796db879157c51 813 PIRSF PIRSF001604 4 649 6.7E-192 T 29-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CDC59_RS09120 6853a16d48da6a8d73796db879157c51 813 PIRSF PIRSF001604 645 809 8.1E-29 T 29-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CDC59_RS09120 6853a16d48da6a8d73796db879157c51 813 SUPERFAMILY SSF47781 436 631 4.13E-52 T 29-03-2018 IPR010994 RuvA domain 2-like CDC59_RS09120 6853a16d48da6a8d73796db879157c51 813 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 129 158 - T 29-03-2018 IPR018239 NAD-dependent DNA ligase, active site CDC59_RS09120 6853a16d48da6a8d73796db879157c51 813 Gene3D G3DSA:3.40.50.10190 621 809 4.1E-24 T 29-03-2018 IPR001357 BRCT domain CDC59_RS09120 6853a16d48da6a8d73796db879157c51 813 SUPERFAMILY SSF52113 730 806 2.62E-19 T 29-03-2018 IPR001357 BRCT domain CDC59_RS09120 6853a16d48da6a8d73796db879157c51 813 Gene3D G3DSA:3.30.470.30 133 269 1.1E-50 T 29-03-2018 CDC59_RS09120 6853a16d48da6a8d73796db879157c51 813 Gene3D G3DSA:1.10.287.610 4 76 5.7E-26 T 29-03-2018 CDC59_RS09120 6853a16d48da6a8d73796db879157c51 813 SMART SM00292 731 808 1.2E-15 T 29-03-2018 IPR001357 BRCT domain CDC59_RS09120 6853a16d48da6a8d73796db879157c51 813 Gene3D G3DSA:1.10.150.20 464 554 2.8E-20 T 29-03-2018 CDC59_RS09120 6853a16d48da6a8d73796db879157c51 813 SUPERFAMILY SSF50249 335 415 2.06E-27 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDC59_RS09120 6853a16d48da6a8d73796db879157c51 813 Gene3D G3DSA:1.10.150.20 555 620 1.6E-22 T 29-03-2018 CDC59_RS09120 6853a16d48da6a8d73796db879157c51 813 SUPERFAMILY SSF56091 13 333 2.26E-108 T 29-03-2018 CDC59_RS09120 6853a16d48da6a8d73796db879157c51 813 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 14 335 3.3E-113 T 29-03-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 CDC59_RS09120 6853a16d48da6a8d73796db879157c51 813 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 339 414 1.9E-34 T 29-03-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 CDC59_RS09120 6853a16d48da6a8d73796db879157c51 813 SMART SM00278 478 497 290.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CDC59_RS09120 6853a16d48da6a8d73796db879157c51 813 SMART SM00278 561 580 280.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CDC59_RS09120 6853a16d48da6a8d73796db879157c51 813 SMART SM00278 593 612 56.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CDC59_RS14880 a596337a8a7a87db1e61b43036bc3100 600 Pfam PF00750 tRNA synthetases class I (R) 108 406 8.4E-18 T 29-03-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 CDC59_RS14880 a596337a8a7a87db1e61b43036bc3100 600 Pfam PF05746 DALR anticodon binding domain 475 600 1.2E-34 T 29-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CDC59_RS14880 a596337a8a7a87db1e61b43036bc3100 600 SMART SM00836 475 600 1.3E-49 T 29-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CDC59_RS14880 a596337a8a7a87db1e61b43036bc3100 600 SMART SM01016 7 95 6.3E-35 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CDC59_RS14880 a596337a8a7a87db1e61b43036bc3100 600 SUPERFAMILY SSF47323 470 600 5.62E-34 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDC59_RS14880 a596337a8a7a87db1e61b43036bc3100 600 SUPERFAMILY SSF52374 121 406 4.79E-81 T 29-03-2018 CDC59_RS14880 a596337a8a7a87db1e61b43036bc3100 600 SUPERFAMILY SSF52374 437 485 4.79E-81 T 29-03-2018 CDC59_RS14880 a596337a8a7a87db1e61b43036bc3100 600 Hamap MF_00123 Arginine--tRNA ligase [argS]. 7 600 25.003 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CDC59_RS14880 a596337a8a7a87db1e61b43036bc3100 600 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 15 600 1.3E-119 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CDC59_RS14880 a596337a8a7a87db1e61b43036bc3100 600 Gene3D G3DSA:1.10.730.10 441 600 2.3E-48 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDC59_RS14880 a596337a8a7a87db1e61b43036bc3100 600 SUPERFAMILY SSF55190 4 115 2.09E-24 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CDC59_RS14880 a596337a8a7a87db1e61b43036bc3100 600 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 8 95 1.6E-22 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CDC59_RS14880 a596337a8a7a87db1e61b43036bc3100 600 PRINTS PR01038 Arginyl-tRNA synthetase signature 139 155 3.0E-21 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CDC59_RS14880 a596337a8a7a87db1e61b43036bc3100 600 PRINTS PR01038 Arginyl-tRNA synthetase signature 312 333 3.0E-21 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CDC59_RS14880 a596337a8a7a87db1e61b43036bc3100 600 PRINTS PR01038 Arginyl-tRNA synthetase signature 124 139 3.0E-21 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CDC59_RS14880 a596337a8a7a87db1e61b43036bc3100 600 PRINTS PR01038 Arginyl-tRNA synthetase signature 163 176 3.0E-21 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CDC59_RS14880 a596337a8a7a87db1e61b43036bc3100 600 Gene3D G3DSA:3.40.50.620 112 374 5.7E-53 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDC59_RS14880 a596337a8a7a87db1e61b43036bc3100 600 Gene3D G3DSA:3.30.1360.70 1 111 1.2E-31 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CDC59_RS14880 a596337a8a7a87db1e61b43036bc3100 600 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 134 143 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDC59_RS12045 72bc4bf930ca72108b60c03ad808da41 435 Pfam PF12002 MgsA AAA+ ATPase C terminal 259 423 5.6E-65 T 29-03-2018 IPR021886 MgsA AAA+ ATPase C-terminal CDC59_RS12045 72bc4bf930ca72108b60c03ad808da41 435 SUPERFAMILY SSF48019 244 429 2.08E-72 T 29-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CDC59_RS12045 72bc4bf930ca72108b60c03ad808da41 435 Pfam PF16193 AAA C-terminal domain 182 258 1.1E-22 T 29-03-2018 IPR032423 AAA C-terminal domain CDC59_RS12045 72bc4bf930ca72108b60c03ad808da41 435 Gene3D G3DSA:1.20.272.10 243 337 4.9E-37 T 29-03-2018 CDC59_RS12045 72bc4bf930ca72108b60c03ad808da41 435 Gene3D G3DSA:1.10.8.60 151 234 2.5E-21 T 29-03-2018 CDC59_RS12045 72bc4bf930ca72108b60c03ad808da41 435 Gene3D G3DSA:1.10.3710.10 340 435 2.1E-33 T 29-03-2018 CDC59_RS12045 72bc4bf930ca72108b60c03ad808da41 435 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 50 158 2.8E-15 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CDC59_RS12045 72bc4bf930ca72108b60c03ad808da41 435 Gene3D G3DSA:3.40.50.300 5 150 1.7E-29 T 29-03-2018 CDC59_RS12045 72bc4bf930ca72108b60c03ad808da41 435 SMART SM00382 46 162 1.1E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS12045 72bc4bf930ca72108b60c03ad808da41 435 SUPERFAMILY SSF52540 8 216 4.91E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS02810 1f33ccbf71eddc0e673550625396f3d1 103 Gene3D G3DSA:3.40.30.10 2 103 1.4E-32 T 29-03-2018 CDC59_RS02810 1f33ccbf71eddc0e673550625396f3d1 103 SUPERFAMILY SSF52833 2 102 7.67E-36 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS02810 1f33ccbf71eddc0e673550625396f3d1 103 Pfam PF00462 Glutaredoxin 17 82 1.5E-19 T 29-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 CDC59_RS02810 1f33ccbf71eddc0e673550625396f3d1 103 PIRSF PIRSF005894 1 103 4.6E-50 T 29-03-2018 IPR014434 Monothiol glutaredoxin GO:0015036 Reactome: R-HSA-1362409 CDC59_RS02810 1f33ccbf71eddc0e673550625396f3d1 103 TIGRFAM TIGR00365 TIGR00365: monothiol glutaredoxin, Grx4 family 5 102 1.3E-46 T 29-03-2018 IPR004480 Monothiol glutaredoxin-related CDC59_RS03470 fc86ca3c15599a4bdda516393f8fa0ce 305 Gene3D G3DSA:3.40.50.10860 8 126 4.1E-35 T 29-03-2018 CDC59_RS03470 fc86ca3c15599a4bdda516393f8fa0ce 305 SUPERFAMILY SSF51735 117 290 3.41E-39 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS03470 fc86ca3c15599a4bdda516393f8fa0ce 305 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 17 290 30.029 T 29-03-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CDC59_RS03470 fc86ca3c15599a4bdda516393f8fa0ce 305 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 22 104 2.0E-21 T 29-03-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CDC59_RS03470 fc86ca3c15599a4bdda516393f8fa0ce 305 SUPERFAMILY SSF53223 17 116 6.91E-29 T 29-03-2018 CDC59_RS03470 fc86ca3c15599a4bdda516393f8fa0ce 305 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 20 292 1.1E-76 T 29-03-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CDC59_RS03470 fc86ca3c15599a4bdda516393f8fa0ce 305 Gene3D G3DSA:3.40.50.720 127 295 1.8E-28 T 29-03-2018 CDC59_RS03470 fc86ca3c15599a4bdda516393f8fa0ce 305 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 127 212 1.6E-8 T 29-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase CDC59_RS01045 7d6d10aa40e83cc98685e74457c7b380 493 Pfam PF06969 HemN C-terminal domain 387 455 1.4E-9 T 29-03-2018 IPR010723 HemN, C-terminal CDC59_RS01045 7d6d10aa40e83cc98685e74457c7b380 493 Gene3D G3DSA:3.20.20.70 55 376 3.1E-48 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS01045 7d6d10aa40e83cc98685e74457c7b380 493 TIGRFAM TIGR00538 hemN: oxygen-independent coproporphyrinogen III oxidase 28 469 1.2E-171 T 29-03-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 CDC59_RS01045 7d6d10aa40e83cc98685e74457c7b380 493 SUPERFAMILY SSF102114 25 468 2.62E-138 T 29-03-2018 CDC59_RS01045 7d6d10aa40e83cc98685e74457c7b380 493 Pfam PF04055 Radical SAM superfamily 80 252 5.0E-18 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CDC59_RS01045 7d6d10aa40e83cc98685e74457c7b380 493 PIRSF PIRSF000167 24 478 1.3E-166 T 29-03-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 CDC59_RS01045 7d6d10aa40e83cc98685e74457c7b380 493 SMART SM00729 75 296 6.2E-50 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CDC59_RS15995 8305b0812f1da3de045abaa291d8947f 635 SMART SM00387 516 631 1.0E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS15995 8305b0812f1da3de045abaa291d8947f 635 Gene3D G3DSA:3.30.450.20 180 308 1.3E-7 T 29-03-2018 CDC59_RS15995 8305b0812f1da3de045abaa291d8947f 635 Pfam PF00512 His Kinase A (phospho-acceptor) domain 407 472 1.7E-6 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS15995 8305b0812f1da3de045abaa291d8947f 635 Gene3D G3DSA:3.30.450.20 70 179 5.8E-20 T 29-03-2018 CDC59_RS15995 8305b0812f1da3de045abaa291d8947f 635 Gene3D G3DSA:1.10.287.130 378 470 6.1E-9 T 29-03-2018 CDC59_RS15995 8305b0812f1da3de045abaa291d8947f 635 PIRSF PIRSF036431 5 635 2.4E-216 T 29-03-2018 IPR017055 Signal transduction histidine kinase, DctB (C4-dicarboxylate transport system regulator) CDC59_RS15995 8305b0812f1da3de045abaa291d8947f 635 Gene3D G3DSA:3.30.565.10 476 633 4.1E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS15995 8305b0812f1da3de045abaa291d8947f 635 SUPERFAMILY SSF103190 101 200 3.4E-17 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CDC59_RS15995 8305b0812f1da3de045abaa291d8947f 635 SUPERFAMILY SSF55874 474 627 6.29E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS15995 8305b0812f1da3de045abaa291d8947f 635 PRINTS PR00344 Bacterial sensor protein C-terminal signature 589 607 8.8E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS15995 8305b0812f1da3de045abaa291d8947f 635 PRINTS PR00344 Bacterial sensor protein C-terminal signature 558 572 8.8E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS15995 8305b0812f1da3de045abaa291d8947f 635 PRINTS PR00344 Bacterial sensor protein C-terminal signature 576 586 8.8E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS15995 8305b0812f1da3de045abaa291d8947f 635 PRINTS PR00344 Bacterial sensor protein C-terminal signature 615 628 8.8E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS15995 8305b0812f1da3de045abaa291d8947f 635 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 518 627 2.4E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS15995 8305b0812f1da3de045abaa291d8947f 635 SMART SM00388 406 474 7.4E-4 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS15995 8305b0812f1da3de045abaa291d8947f 635 Pfam PF02743 Cache domain 61 303 6.3E-17 T 29-03-2018 IPR033479 Double Cache domain 1 CDC59_RS15995 8305b0812f1da3de045abaa291d8947f 635 SUPERFAMILY SSF47384 402 471 3.34E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS01025 b6ed8e9599821fb7c65b42dc24b06ec2 179 Pfam PF12306 Inclusion body protein 16 175 2.1E-16 T 29-03-2018 IPR021087 Uncharacterised protein family PixA/AidA CDC59_RS07170 7b2bec4e7b75fedfb52f8bee114fc35e 621 Pfam PF00012 Hsp70 protein 21 602 1.6E-180 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CDC59_RS07170 7b2bec4e7b75fedfb52f8bee114fc35e 621 SUPERFAMILY SSF100920 388 539 5.23E-49 T 29-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CDC59_RS07170 7b2bec4e7b75fedfb52f8bee114fc35e 621 TIGRFAM TIGR01991 HscA: Fe-S protein assembly chaperone HscA 21 619 1.4E-286 T 29-03-2018 IPR010236 ISC system FeS cluster assembly, HscA chaperone GO:0005524|GO:0006457|GO:0016226|GO:0016887|GO:0051082 CDC59_RS07170 7b2bec4e7b75fedfb52f8bee114fc35e 621 SUPERFAMILY SSF53067 199 379 2.52E-48 T 29-03-2018 CDC59_RS07170 7b2bec4e7b75fedfb52f8bee114fc35e 621 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 24 31 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CDC59_RS07170 7b2bec4e7b75fedfb52f8bee114fc35e 621 SUPERFAMILY SSF100934 508 619 8.83E-36 T 29-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain CDC59_RS07170 7b2bec4e7b75fedfb52f8bee114fc35e 621 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 204 217 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CDC59_RS07170 7b2bec4e7b75fedfb52f8bee114fc35e 621 Gene3D G3DSA:3.30.420.40 20 209 1.5E-58 T 29-03-2018 CDC59_RS07170 7b2bec4e7b75fedfb52f8bee114fc35e 621 Gene3D G3DSA:3.30.420.40 210 362 6.1E-37 T 29-03-2018 CDC59_RS07170 7b2bec4e7b75fedfb52f8bee114fc35e 621 SUPERFAMILY SSF53067 19 195 1.13E-53 T 29-03-2018 CDC59_RS07170 7b2bec4e7b75fedfb52f8bee114fc35e 621 Gene3D G3DSA:1.20.1270.10 533 619 4.2E-15 T 29-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain CDC59_RS07170 7b2bec4e7b75fedfb52f8bee114fc35e 621 Gene3D G3DSA:2.60.34.10 391 532 3.4E-48 T 29-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CDC59_RS07170 7b2bec4e7b75fedfb52f8bee114fc35e 621 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 335 349 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CDC59_RS07170 7b2bec4e7b75fedfb52f8bee114fc35e 621 Hamap MF_00679 Chaperone protein HscA [hscA]. 1 620 45.443 T 29-03-2018 IPR010236 ISC system FeS cluster assembly, HscA chaperone GO:0005524|GO:0006457|GO:0016226|GO:0016887|GO:0051082 CDC59_RS07170 7b2bec4e7b75fedfb52f8bee114fc35e 621 PRINTS PR00301 70kDa heat shock protein signature 48 60 1.2E-54 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CDC59_RS07170 7b2bec4e7b75fedfb52f8bee114fc35e 621 PRINTS PR00301 70kDa heat shock protein signature 470 486 1.2E-54 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CDC59_RS07170 7b2bec4e7b75fedfb52f8bee114fc35e 621 PRINTS PR00301 70kDa heat shock protein signature 332 348 1.2E-54 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CDC59_RS07170 7b2bec4e7b75fedfb52f8bee114fc35e 621 PRINTS PR00301 70kDa heat shock protein signature 20 33 1.2E-54 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CDC59_RS07170 7b2bec4e7b75fedfb52f8bee114fc35e 621 PRINTS PR00301 70kDa heat shock protein signature 389 408 1.2E-54 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CDC59_RS07170 7b2bec4e7b75fedfb52f8bee114fc35e 621 PRINTS PR00301 70kDa heat shock protein signature 210 220 1.2E-54 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CDC59_RS07170 7b2bec4e7b75fedfb52f8bee114fc35e 621 PRINTS PR00301 70kDa heat shock protein signature 363 383 1.2E-54 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CDC59_RS07170 7b2bec4e7b75fedfb52f8bee114fc35e 621 PRINTS PR00301 70kDa heat shock protein signature 151 171 1.2E-54 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CDC59_RS00965 acaea2ba0a0da317fd05f32ece41b052 336 Pfam PF05114 Protein of unknown function (DUF692) 12 285 3.9E-98 T 29-03-2018 IPR007801 Uncharacterised protein family UPF0276 CDC59_RS00965 acaea2ba0a0da317fd05f32ece41b052 336 Gene3D G3DSA:3.20.20.150 8 290 8.9E-80 T 29-03-2018 CDC59_RS00965 acaea2ba0a0da317fd05f32ece41b052 336 SUPERFAMILY SSF51658 31 218 1.65E-15 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CDC59_RS18670 325e31e45badccaa696f1dde9a284336 428 Pfam PF07732 Multicopper oxidase 86 192 5.0E-36 T 29-03-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 CDC59_RS18670 325e31e45badccaa696f1dde9a284336 428 ProSitePatterns PS00080 Multicopper oxidases signature 2. 316 327 - T 29-03-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 CDC59_RS18670 325e31e45badccaa696f1dde9a284336 428 SUPERFAMILY SSF49503 63 192 2.26E-38 T 29-03-2018 IPR008972 Cupredoxin CDC59_RS18670 325e31e45badccaa696f1dde9a284336 428 Pfam PF07731 Multicopper oxidase 217 333 8.6E-22 T 29-03-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 CDC59_RS18670 325e31e45badccaa696f1dde9a284336 428 SUPERFAMILY SSF49503 173 329 1.7E-31 T 29-03-2018 IPR008972 Cupredoxin CDC59_RS18670 325e31e45badccaa696f1dde9a284336 428 Gene3D G3DSA:2.60.40.420 42 190 4.2E-34 T 29-03-2018 IPR008972 Cupredoxin CDC59_RS18670 325e31e45badccaa696f1dde9a284336 428 Gene3D G3DSA:2.60.40.420 201 369 2.6E-34 T 29-03-2018 IPR008972 Cupredoxin CDC59_RS03415 81b1eda9a483dd3005da9635c11a9530 298 Gene3D G3DSA:3.40.50.720 4 112 0.19 T 29-03-2018 CDC59_RS03415 81b1eda9a483dd3005da9635c11a9530 298 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 3 296 32.646 T 29-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 CDC59_RS03415 81b1eda9a483dd3005da9635c11a9530 298 Gene3D G3DSA:3.40.50.150 113 295 5.4E-40 T 29-03-2018 CDC59_RS03415 81b1eda9a483dd3005da9635c11a9530 298 SUPERFAMILY SSF53335 70 292 3.47E-46 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS03415 81b1eda9a483dd3005da9635c11a9530 298 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 4 290 2.5E-69 T 29-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 CDC59_RS03415 81b1eda9a483dd3005da9635c11a9530 298 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 3 296 3.4E-92 T 29-03-2018 CDC59_RS03415 81b1eda9a483dd3005da9635c11a9530 298 PIRSF PIRSF000401 1 298 7.6E-102 T 29-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 CDC59_RS23840 efe5c66606f9e2efe2c84d5dfe0e4940 335 SUPERFAMILY SSF52317 24 215 4.89E-42 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CDC59_RS23840 efe5c66606f9e2efe2c84d5dfe0e4940 335 Pfam PF12833 Helix-turn-helix domain 254 331 1.3E-20 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CDC59_RS23840 efe5c66606f9e2efe2c84d5dfe0e4940 335 SUPERFAMILY SSF46689 234 281 4.66E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS23840 efe5c66606f9e2efe2c84d5dfe0e4940 335 Pfam PF01965 DJ-1/PfpI family 24 196 9.6E-19 T 29-03-2018 IPR002818 DJ-1/PfpI CDC59_RS23840 efe5c66606f9e2efe2c84d5dfe0e4940 335 SUPERFAMILY SSF46689 284 332 8.96E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS23840 efe5c66606f9e2efe2c84d5dfe0e4940 335 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 285 326 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CDC59_RS23840 efe5c66606f9e2efe2c84d5dfe0e4940 335 SMART SM00342 248 330 3.1E-24 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CDC59_RS23840 efe5c66606f9e2efe2c84d5dfe0e4940 335 Gene3D G3DSA:1.10.10.60 248 292 7.5E-10 T 29-03-2018 CDC59_RS23840 efe5c66606f9e2efe2c84d5dfe0e4940 335 Gene3D G3DSA:1.10.10.60 293 333 1.7E-10 T 29-03-2018 CDC59_RS23840 efe5c66606f9e2efe2c84d5dfe0e4940 335 Gene3D G3DSA:3.40.50.880 19 247 6.3E-53 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CDC59_RS19915 ecb0f90ac83dd38ec9d83433049b435d 139 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 87 132 5.1E-10 T 29-03-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS19915 ecb0f90ac83dd38ec9d83433049b435d 139 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 4 132 1.8E-41 T 29-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS19915 ecb0f90ac83dd38ec9d83433049b435d 139 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 9 85 1.0E-36 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS19915 ecb0f90ac83dd38ec9d83433049b435d 139 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 4 83 2.1E-27 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS19915 ecb0f90ac83dd38ec9d83433049b435d 139 SUPERFAMILY SSF51344 3 85 5.36E-24 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS19915 ecb0f90ac83dd38ec9d83433049b435d 139 Gene3D G3DSA:2.60.15.10 2 89 2.0E-27 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS19915 ecb0f90ac83dd38ec9d83433049b435d 139 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 2 130 21.176 T 29-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS19915 ecb0f90ac83dd38ec9d83433049b435d 139 SUPERFAMILY SSF46604 88 135 4.71E-13 T 29-03-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS19915 ecb0f90ac83dd38ec9d83433049b435d 139 Gene3D G3DSA:1.20.5.440 90 130 3.4E-9 T 29-03-2018 CDC59_RS09240 f87b699b03563b699cc3e644615f4eb6 298 Gene3D G3DSA:1.20.1260.10 31 208 9.8E-13 T 29-03-2018 IPR012347 Ferritin-related CDC59_RS09240 f87b699b03563b699cc3e644615f4eb6 298 PIRSF PIRSF007580 1 288 5.7E-101 T 29-03-2018 IPR016516 Uncharacterised conserved protein UCP07580 CDC59_RS09240 f87b699b03563b699cc3e644615f4eb6 298 Pfam PF10118 Predicted metal-dependent hydrolase 9 268 2.4E-75 T 29-03-2018 IPR016516 Uncharacterised conserved protein UCP07580 CDC59_RS17780 410739bb38a28f7b7d32de257fda8505 752 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 15 103 1.0E-15 T 29-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 CDC59_RS17780 410739bb38a28f7b7d32de257fda8505 752 SMART SM00642 142 576 5.3E-7 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CDC59_RS17780 410739bb38a28f7b7d32de257fda8505 752 SUPERFAMILY SSF51011 597 698 1.73E-16 T 29-03-2018 CDC59_RS17780 410739bb38a28f7b7d32de257fda8505 752 Gene3D G3DSA:3.20.20.80 147 588 2.1E-106 T 29-03-2018 CDC59_RS17780 410739bb38a28f7b7d32de257fda8505 752 Pfam PF00128 Alpha amylase, catalytic domain 201 283 6.9E-5 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CDC59_RS17780 410739bb38a28f7b7d32de257fda8505 752 Gene3D G3DSA:2.60.40.10 10 146 2.1E-42 T 29-03-2018 IPR013783 Immunoglobulin-like fold CDC59_RS17780 410739bb38a28f7b7d32de257fda8505 752 Gene3D G3DSA:2.60.40.1180 589 701 1.8E-20 T 29-03-2018 CDC59_RS17780 410739bb38a28f7b7d32de257fda8505 752 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 11 696 0.0 T 29-03-2018 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 CDC59_RS17780 410739bb38a28f7b7d32de257fda8505 752 SUPERFAMILY SSF81296 10 157 1.09E-47 T 29-03-2018 IPR014756 Immunoglobulin E-set CDC59_RS17780 410739bb38a28f7b7d32de257fda8505 752 SUPERFAMILY SSF51445 506 583 6.74E-124 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CDC59_RS17780 410739bb38a28f7b7d32de257fda8505 752 SUPERFAMILY SSF51445 143 477 6.74E-124 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CDC59_RS05770 c6d86308f7d62e59394df5590ab5c15b 431 Gene3D G3DSA:3.40.50.1100 29 214 3.9E-38 T 29-03-2018 CDC59_RS05770 c6d86308f7d62e59394df5590ab5c15b 431 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 22 413 45.531 T 29-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CDC59_RS05770 c6d86308f7d62e59394df5590ab5c15b 431 SUPERFAMILY SSF53686 23 411 5.37E-125 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CDC59_RS05770 c6d86308f7d62e59394df5590ab5c15b 431 PIRSF PIRSF001413 15 419 1.6E-143 T 29-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CDC59_RS05770 c6d86308f7d62e59394df5590ab5c15b 431 Gene3D G3DSA:3.40.50.1100 215 417 3.9E-32 T 29-03-2018 CDC59_RS05770 c6d86308f7d62e59394df5590ab5c15b 431 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 27 412 8.5E-173 T 29-03-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CDC59_RS05770 c6d86308f7d62e59394df5590ab5c15b 431 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 73 399 8.4E-43 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CDC59_RS05770 c6d86308f7d62e59394df5590ab5c15b 431 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 101 115 - T 29-03-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CDC59_RS02595 6037f6896c228b39b4c81b73a3934cdd 217 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 3 215 34.545 T 29-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CDC59_RS02595 6037f6896c228b39b4c81b73a3934cdd 217 Gene3D G3DSA:3.40.50.880 1 216 2.5E-43 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CDC59_RS02595 6037f6896c228b39b4c81b73a3934cdd 217 SUPERFAMILY SSF52317 2 215 1.16E-50 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CDC59_RS02595 6037f6896c228b39b4c81b73a3934cdd 217 PIRSF PIRSF000495 2 217 1.6E-64 T 29-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CDC59_RS02595 6037f6896c228b39b4c81b73a3934cdd 217 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 4 214 9.6E-60 T 29-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CDC59_RS02595 6037f6896c228b39b4c81b73a3934cdd 217 Pfam PF00117 Glutamine amidotransferase class-I 6 212 3.0E-17 T 29-03-2018 IPR017926 Glutamine amidotransferase CDC59_RS14190 85e3cc91227cc4b87e930c24e6b8574d 192 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 4 186 5.4E-57 T 29-03-2018 IPR006286 Peptidase C56, PfpI CDC59_RS14190 85e3cc91227cc4b87e930c24e6b8574d 192 SUPERFAMILY SSF52317 3 187 1.58E-53 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CDC59_RS14190 85e3cc91227cc4b87e930c24e6b8574d 192 Gene3D G3DSA:3.40.50.880 1 191 1.3E-43 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CDC59_RS14190 85e3cc91227cc4b87e930c24e6b8574d 192 Pfam PF01965 DJ-1/PfpI family 3 184 2.2E-53 T 29-03-2018 IPR002818 DJ-1/PfpI CDC59_RS09400 41fed800a03fdfbc25f61b95d03d6d09 158 SUPERFAMILY SSF55620 4 149 3.89E-38 T 29-03-2018 CDC59_RS09400 41fed800a03fdfbc25f61b95d03d6d09 158 PIRSF PIRSF006113 97 152 1.0 T 29-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 CDC59_RS09400 41fed800a03fdfbc25f61b95d03d6d09 158 PIRSF PIRSF006113 2 84 1.6E-17 T 29-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 CDC59_RS09400 41fed800a03fdfbc25f61b95d03d6d09 158 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 7 150 1.5E-33 T 29-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 CDC59_RS09400 41fed800a03fdfbc25f61b95d03d6d09 158 TIGRFAM TIGR03367 queuosine_QueD: queuosine biosynthesis protein QueD 7 121 6.8E-27 T 29-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 CDC59_RS09400 41fed800a03fdfbc25f61b95d03d6d09 158 Gene3D G3DSA:3.30.479.10 1 152 7.8E-36 T 29-03-2018 CDC59_RS02205 d17ec8030e53af4dfe96704e28747122 637 SUPERFAMILY SSF52540 9 178 2.15E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS02205 d17ec8030e53af4dfe96704e28747122 637 SUPERFAMILY SSF52540 323 365 2.15E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS02205 d17ec8030e53af4dfe96704e28747122 637 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 25 484 4.6E-149 T 29-03-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 CDC59_RS02205 d17ec8030e53af4dfe96704e28747122 637 Pfam PF00270 DEAD/DEAH box helicase 39 198 4.4E-20 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CDC59_RS02205 d17ec8030e53af4dfe96704e28747122 637 Pfam PF00271 Helicase conserved C-terminal domain 257 348 8.1E-15 T 29-03-2018 IPR001650 Helicase, C-terminal CDC59_RS02205 d17ec8030e53af4dfe96704e28747122 637 SMART SM00490 268 349 8.0E-25 T 29-03-2018 IPR001650 Helicase, C-terminal CDC59_RS02205 d17ec8030e53af4dfe96704e28747122 637 SMART SM00956 429 536 1.8E-50 T 29-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 CDC59_RS02205 d17ec8030e53af4dfe96704e28747122 637 SUPERFAMILY SSF52540 221 472 1.29E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS02205 d17ec8030e53af4dfe96704e28747122 637 SMART SM00487 31 231 3.0E-29 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CDC59_RS02205 d17ec8030e53af4dfe96704e28747122 637 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 23 630 4.7E-235 T 29-03-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 CDC59_RS02205 d17ec8030e53af4dfe96704e28747122 637 Gene3D G3DSA:3.40.50.300 223 373 1.8E-28 T 29-03-2018 CDC59_RS02205 d17ec8030e53af4dfe96704e28747122 637 Gene3D G3DSA:1.10.150.80 545 637 4.0E-23 T 29-03-2018 CDC59_RS02205 d17ec8030e53af4dfe96704e28747122 637 Gene3D G3DSA:1.10.10.10 374 544 4.4E-47 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS02205 d17ec8030e53af4dfe96704e28747122 637 Pfam PF09382 RQC domain 424 538 5.5E-37 T 29-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 CDC59_RS02205 d17ec8030e53af4dfe96704e28747122 637 Pfam PF00570 HRDC domain 566 629 7.6E-21 T 29-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 CDC59_RS02205 d17ec8030e53af4dfe96704e28747122 637 SUPERFAMILY SSF47819 558 632 5.67E-19 T 29-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 CDC59_RS02205 d17ec8030e53af4dfe96704e28747122 637 Pfam PF16124 RecQ zinc-binding 361 422 7.5E-18 T 29-03-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain CDC59_RS02205 d17ec8030e53af4dfe96704e28747122 637 Gene3D G3DSA:3.40.50.300 17 221 3.6E-32 T 29-03-2018 CDC59_RS02205 d17ec8030e53af4dfe96704e28747122 637 SMART SM00341 560 637 1.5E-10 T 29-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 CDC59_RS02295 ad99b0403537c2f03e67fb33f20ca750 180 Pfam PF00281 Ribosomal protein L5 25 81 1.0E-26 T 29-03-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS02295 ad99b0403537c2f03e67fb33f20ca750 180 PIRSF PIRSF002161 1 180 6.1E-62 T 29-03-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS02295 ad99b0403537c2f03e67fb33f20ca750 180 ProSitePatterns PS00358 Ribosomal protein L5 signature. 58 74 - T 29-03-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS02295 ad99b0403537c2f03e67fb33f20ca750 180 Pfam PF00673 ribosomal L5P family C-terminus 85 178 1.5E-38 T 29-03-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS02295 ad99b0403537c2f03e67fb33f20ca750 180 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 2 180 43.88 T 29-03-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS02295 ad99b0403537c2f03e67fb33f20ca750 180 SUPERFAMILY SSF55282 4 180 3.3E-75 T 29-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS02295 ad99b0403537c2f03e67fb33f20ca750 180 Gene3D G3DSA:3.30.1440.10 2 180 2.8E-74 T 29-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS04810 880522eb27d911d5147e733353ace20a 272 Pfam PF03649 Uncharacterised protein family (UPF0014) 13 253 3.0E-84 T 29-03-2018 IPR005226 UPF0014 family CDC59_RS04810 880522eb27d911d5147e733353ace20a 272 TIGRFAM TIGR00245 TIGR00245: TIGR00245 family protein 15 259 2.9E-61 T 29-03-2018 IPR005226 UPF0014 family CDC59_RS09350 403492bd03cfd226f7948a1f94e0c0be 232 Pfam PF00775 Dioxygenase 66 218 1.0E-18 T 29-03-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 CDC59_RS09350 403492bd03cfd226f7948a1f94e0c0be 232 ProSitePatterns PS00083 Intradiol ring-cleavage dioxygenases signature. 74 102 - T 29-03-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 CDC59_RS09350 403492bd03cfd226f7948a1f94e0c0be 232 SUPERFAMILY SSF49482 26 231 4.71E-58 T 29-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CDC59_RS09350 403492bd03cfd226f7948a1f94e0c0be 232 TIGRFAM TIGR02423 protocat_alph: protocatechuate 3,4-dioxygenase, alpha subunit 31 232 5.0E-73 T 29-03-2018 IPR012786 Protocatechuate 3,4-dioxygenase, alpha subunit GO:0005506|GO:0018578|GO:0019439|GO:0055114 KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3 CDC59_RS09350 403492bd03cfd226f7948a1f94e0c0be 232 Gene3D G3DSA:2.60.130.10 2 232 1.1E-50 T 29-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CDC59_RS11960 d06a94269eb30ae08134dd7302dc1847 366 SUPERFAMILY SSF46785 4 133 2.18E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS11960 d06a94269eb30ae08134dd7302dc1847 366 Gene3D G3DSA:1.10.10.10 13 112 1.6E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS11960 d06a94269eb30ae08134dd7302dc1847 366 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 24 81 2.3E-11 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS11960 d06a94269eb30ae08134dd7302dc1847 366 Gene3D G3DSA:3.40.190.10 277 366 7.1E-7 T 29-03-2018 CDC59_RS11960 d06a94269eb30ae08134dd7302dc1847 366 Gene3D G3DSA:3.40.190.10 203 276 1.6E-4 T 29-03-2018 CDC59_RS11960 d06a94269eb30ae08134dd7302dc1847 366 SUPERFAMILY SSF53850 119 322 1.03E-6 T 29-03-2018 CDC59_RS11960 d06a94269eb30ae08134dd7302dc1847 366 Pfam PF12727 PBP superfamily domain 134 322 1.2E-46 T 29-03-2018 IPR024370 PBP domain CDC59_RS03125 0344fda89fe4af4e4730114ae7aa50d9 413 Pfam PF01098 Cell cycle protein 44 405 1.2E-105 T 29-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 CDC59_RS03125 0344fda89fe4af4e4730114ae7aa50d9 413 Hamap MF_00913 Putative lipid II flippase FtsW [ftsW]. 39 412 39.922 T 29-03-2018 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 CDC59_RS03125 0344fda89fe4af4e4730114ae7aa50d9 413 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 42 403 6.0E-124 T 29-03-2018 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 CDC59_RS10645 bf099ae4475b0f1eb1abbf733f446ad7 193 Gene3D G3DSA:1.20.5.40 108 124 2.7E-5 T 29-03-2018 CDC59_RS10645 bf099ae4475b0f1eb1abbf733f446ad7 193 SMART SM00857 3 141 1.6E-27 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CDC59_RS10645 bf099ae4475b0f1eb1abbf733f446ad7 193 SUPERFAMILY SSF53041 1 133 1.29E-27 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CDC59_RS10645 bf099ae4475b0f1eb1abbf733f446ad7 193 Gene3D G3DSA:3.40.50.1390 1 107 3.9E-22 T 29-03-2018 CDC59_RS10645 bf099ae4475b0f1eb1abbf733f446ad7 193 Pfam PF00239 Resolvase, N terminal domain 4 133 2.5E-27 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CDC59_RS10645 bf099ae4475b0f1eb1abbf733f446ad7 193 Gene3D G3DSA:1.10.10.60 125 192 0.0014 T 29-03-2018 CDC59_RS09465 cbcf02692c1d3a17d9cb209ab7e87232 367 Gene3D G3DSA:3.40.50.720 1 358 3.1E-36 T 29-03-2018 CDC59_RS09465 cbcf02692c1d3a17d9cb209ab7e87232 367 Pfam PF07993 Male sterility protein 5 233 8.8E-27 T 29-03-2018 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 CDC59_RS09465 cbcf02692c1d3a17d9cb209ab7e87232 367 SUPERFAMILY SSF51735 316 351 1.7E-39 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS09465 cbcf02692c1d3a17d9cb209ab7e87232 367 SUPERFAMILY SSF51735 1 267 1.7E-39 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS03910 56d2c7ca710da12479805c5fe7c2aba2 165 ProSitePatterns PS00460 Glutathione peroxidases active site. 24 39 - T 29-03-2018 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 CDC59_RS03910 56d2c7ca710da12479805c5fe7c2aba2 165 PIRSF PIRSF000303 1 162 1.6E-66 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CDC59_RS03910 56d2c7ca710da12479805c5fe7c2aba2 165 ProSitePatterns PS00763 Glutathione peroxidases signature 2. 60 67 - T 29-03-2018 IPR029760 Glutathione peroxidase conserved site Reactome: R-HSA-3299685 CDC59_RS03910 56d2c7ca710da12479805c5fe7c2aba2 165 Pfam PF00255 Glutathione peroxidase 4 110 3.6E-44 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CDC59_RS03910 56d2c7ca710da12479805c5fe7c2aba2 165 Gene3D G3DSA:3.40.30.10 2 161 5.3E-48 T 29-03-2018 CDC59_RS03910 56d2c7ca710da12479805c5fe7c2aba2 165 PRINTS PR01011 Glutathione peroxidase family signature 123 132 5.3E-22 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CDC59_RS03910 56d2c7ca710da12479805c5fe7c2aba2 165 PRINTS PR01011 Glutathione peroxidase family signature 57 73 5.3E-22 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CDC59_RS03910 56d2c7ca710da12479805c5fe7c2aba2 165 PRINTS PR01011 Glutathione peroxidase family signature 22 39 5.3E-22 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CDC59_RS03910 56d2c7ca710da12479805c5fe7c2aba2 165 SUPERFAMILY SSF52833 3 159 2.32E-61 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS12615 3f3d50d2ca577cefe15668002aa828c3 464 SUPERFAMILY SSF53335 160 462 3.72E-70 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS12615 3f3d50d2ca577cefe15668002aa828c3 464 Gene3D G3DSA:3.30.70.1170 195 252 5.5E-18 T 29-03-2018 CDC59_RS12615 3f3d50d2ca577cefe15668002aa828c3 464 Pfam PF01189 16S rRNA methyltransferase RsmB/F 262 460 1.7E-50 T 29-03-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CDC59_RS12615 3f3d50d2ca577cefe15668002aa828c3 464 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 445 462 3.5E-28 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CDC59_RS12615 3f3d50d2ca577cefe15668002aa828c3 464 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 342 354 3.5E-28 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CDC59_RS12615 3f3d50d2ca577cefe15668002aa828c3 464 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 273 283 3.5E-28 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CDC59_RS12615 3f3d50d2ca577cefe15668002aa828c3 464 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 244 258 3.5E-28 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CDC59_RS12615 3f3d50d2ca577cefe15668002aa828c3 464 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 392 408 3.5E-28 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CDC59_RS12615 3f3d50d2ca577cefe15668002aa828c3 464 Gene3D G3DSA:3.40.50.150 253 464 1.0E-57 T 29-03-2018 CDC59_RS04840 d90f062080934a65676b431b233cbbe4 212 Pfam PF00578 AhpC/TSA family 6 134 2.5E-31 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CDC59_RS04840 d90f062080934a65676b431b233cbbe4 212 PIRSF PIRSF000239 1 209 9.5E-79 T 29-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CDC59_RS04840 d90f062080934a65676b431b233cbbe4 212 Gene3D G3DSA:3.30.1020.10 152 212 6.9E-24 T 29-03-2018 CDC59_RS04840 d90f062080934a65676b431b233cbbe4 212 Gene3D G3DSA:3.40.30.10 1 151 4.7E-40 T 29-03-2018 CDC59_RS04840 d90f062080934a65676b431b233cbbe4 212 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 156 191 1.1E-9 T 29-03-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CDC59_RS04840 d90f062080934a65676b431b233cbbe4 212 SUPERFAMILY SSF52833 3 209 1.41E-69 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS19115 c24bbadc5b2454d8cb3251ea593be2c8 640 Gene3D G3DSA:1.10.8.80 247 336 8.4E-24 T 29-03-2018 CDC59_RS19115 c24bbadc5b2454d8cb3251ea593be2c8 640 TIGRFAM TIGR02442 Cob-chelat-sub: cobaltochelatase subunit 5 623 1.4E-253 T 29-03-2018 IPR012804 Cobaltochelatase subunit, putative CDC59_RS19115 c24bbadc5b2454d8cb3251ea593be2c8 640 Gene3D G3DSA:3.40.50.410 440 614 3.4E-22 T 29-03-2018 IPR002035 von Willebrand factor, type A CDC59_RS19115 c24bbadc5b2454d8cb3251ea593be2c8 640 SMART SM00382 28 205 1.6E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS19115 c24bbadc5b2454d8cb3251ea593be2c8 640 Pfam PF13519 von Willebrand factor type A domain 461 563 4.3E-14 T 29-03-2018 IPR002035 von Willebrand factor, type A CDC59_RS19115 c24bbadc5b2454d8cb3251ea593be2c8 640 Pfam PF01078 Magnesium chelatase, subunit ChlI 112 182 6.1E-7 T 29-03-2018 IPR000523 Magnesium chelatase ChlI domain CDC59_RS19115 c24bbadc5b2454d8cb3251ea593be2c8 640 SUPERFAMILY SSF52540 3 329 6.58E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS19115 c24bbadc5b2454d8cb3251ea593be2c8 640 SMART SM00327 458 634 3.4E-13 T 29-03-2018 IPR002035 von Willebrand factor, type A CDC59_RS19115 c24bbadc5b2454d8cb3251ea593be2c8 640 SUPERFAMILY SSF53300 461 616 2.02E-20 T 29-03-2018 IPR002035 von Willebrand factor, type A CDC59_RS19115 c24bbadc5b2454d8cb3251ea593be2c8 640 Gene3D G3DSA:3.40.50.300 2 202 3.5E-23 T 29-03-2018 CDC59_RS13950 c3c1906e0e7da29d8d29350fef99994f 525 Pfam PF03109 ABC1 family 108 229 2.7E-32 T 29-03-2018 IPR004147 UbiB domain CDC59_RS13950 c3c1906e0e7da29d8d29350fef99994f 525 Hamap MF_00414 Probable protein kinase UbiB [ubiB]. 1 525 51.626 T 29-03-2018 IPR010232 Probable protein kinase UbiB GO:0006744 CDC59_RS13950 c3c1906e0e7da29d8d29350fef99994f 525 Gene3D G3DSA:3.30.200.20 99 243 1.6E-23 T 29-03-2018 CDC59_RS13950 c3c1906e0e7da29d8d29350fef99994f 525 TIGRFAM TIGR01982 UbiB: 2-polyprenylphenol 6-hydroxylase 4 443 6.4E-170 T 29-03-2018 IPR010232 Probable protein kinase UbiB GO:0006744 CDC59_RS13950 c3c1906e0e7da29d8d29350fef99994f 525 SUPERFAMILY SSF56112 192 435 3.14E-42 T 29-03-2018 IPR011009 Protein kinase-like domain CDC59_RS13950 c3c1906e0e7da29d8d29350fef99994f 525 SUPERFAMILY SSF56112 90 157 3.14E-42 T 29-03-2018 IPR011009 Protein kinase-like domain CDC59_RS08580 b464bd32ee970e7c3cde6680c3f8ee3f 518 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 21 501 6.6E-161 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CDC59_RS08580 b464bd32ee970e7c3cde6680c3f8ee3f 518 Gene3D G3DSA:1.20.1250.20 19 205 6.1E-32 T 29-03-2018 CDC59_RS08580 b464bd32ee970e7c3cde6680c3f8ee3f 518 SUPERFAMILY SSF103473 479 504 1.7E-64 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS08580 b464bd32ee970e7c3cde6680c3f8ee3f 518 SUPERFAMILY SSF103473 10 203 1.7E-64 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS08580 b464bd32ee970e7c3cde6680c3f8ee3f 518 SUPERFAMILY SSF103473 256 427 1.7E-64 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS08580 b464bd32ee970e7c3cde6680c3f8ee3f 518 Gene3D G3DSA:1.20.1250.20 260 513 6.0E-24 T 29-03-2018 CDC59_RS08580 b464bd32ee970e7c3cde6680c3f8ee3f 518 Pfam PF07690 Major Facilitator Superfamily 24 416 1.3E-50 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDC59_RS08580 b464bd32ee970e7c3cde6680c3f8ee3f 518 PRINTS PR01036 Tetracycline resistance protein TetB signature 346 366 5.3E-5 T 29-03-2018 CDC59_RS08580 b464bd32ee970e7c3cde6680c3f8ee3f 518 PRINTS PR01036 Tetracycline resistance protein TetB signature 144 168 5.3E-5 T 29-03-2018 CDC59_RS08580 b464bd32ee970e7c3cde6680c3f8ee3f 518 PRINTS PR01036 Tetracycline resistance protein TetB signature 114 134 5.3E-5 T 29-03-2018 CDC59_RS08580 b464bd32ee970e7c3cde6680c3f8ee3f 518 PRINTS PR01036 Tetracycline resistance protein TetB signature 23 47 5.3E-5 T 29-03-2018 CDC59_RS04855 406480e99ef00737736c97c1915d8b80 273 Pfam PF09339 IclR helix-turn-helix domain 24 74 3.1E-13 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CDC59_RS04855 406480e99ef00737736c97c1915d8b80 273 SUPERFAMILY SSF46785 22 95 1.87E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS04855 406480e99ef00737736c97c1915d8b80 273 Gene3D G3DSA:1.10.10.10 5 83 6.7E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS04855 406480e99ef00737736c97c1915d8b80 273 Pfam PF01614 Bacterial transcriptional regulator 147 265 1.1E-9 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CDC59_RS04855 406480e99ef00737736c97c1915d8b80 273 SUPERFAMILY SSF55781 89 268 9.16E-32 T 29-03-2018 IPR029016 GAF domain-like CDC59_RS04855 406480e99ef00737736c97c1915d8b80 273 SMART SM00346 22 112 1.1E-18 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CDC59_RS04855 406480e99ef00737736c97c1915d8b80 273 Gene3D G3DSA:3.30.450.40 88 272 1.1E-33 T 29-03-2018 IPR029016 GAF domain-like CDC59_RS05545 c5e99cf9fdfad8d23d288309053acdfe 469 Pfam PF05598 Transposase domain (DUF772) 192 267 9.1E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS05545 c5e99cf9fdfad8d23d288309053acdfe 469 SUPERFAMILY SSF47413 4 78 3.38E-13 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDC59_RS05545 c5e99cf9fdfad8d23d288309053acdfe 469 Pfam PF01609 Transposase DDE domain 279 453 4.5E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS05545 c5e99cf9fdfad8d23d288309053acdfe 469 SMART SM00530 14 69 7.9E-12 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDC59_RS05545 c5e99cf9fdfad8d23d288309053acdfe 469 Pfam PF01381 Helix-turn-helix 15 69 1.7E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDC59_RS05545 c5e99cf9fdfad8d23d288309053acdfe 469 Gene3D G3DSA:1.10.260.40 10 108 4.3E-14 T 29-03-2018 CDC59_RS21955 64f9bea57940213169b39733c4c9ed72 136 SUPERFAMILY SSF56024 24 114 5.16E-16 T 29-03-2018 CDC59_RS21955 64f9bea57940213169b39733c4c9ed72 136 Pfam PF13091 PLD-like domain 28 80 2.8E-11 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CDC59_RS21955 64f9bea57940213169b39733c4c9ed72 136 Gene3D G3DSA:3.30.870.10 3 116 4.3E-16 T 29-03-2018 CDC59_RS21955 64f9bea57940213169b39733c4c9ed72 136 SMART SM00155 28 55 6.9E-5 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CDC59_RS04715 e759fc75e83dad769d4b525b79ce3239 415 PIRSF PIRSF000412 1 415 4.7E-168 T 29-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CDC59_RS04715 e759fc75e83dad769d4b525b79ce3239 415 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 8 415 52.72 T 29-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CDC59_RS04715 e759fc75e83dad769d4b525b79ce3239 415 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 222 238 - T 29-03-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CDC59_RS04715 e759fc75e83dad769d4b525b79ce3239 415 Pfam PF00464 Serine hydroxymethyltransferase 10 384 4.3E-175 T 29-03-2018 CDC59_RS04715 e759fc75e83dad769d4b525b79ce3239 415 Gene3D G3DSA:3.40.640.10 38 273 8.4E-53 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDC59_RS04715 e759fc75e83dad769d4b525b79ce3239 415 SUPERFAMILY SSF53383 8 414 6.95E-181 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS04715 e759fc75e83dad769d4b525b79ce3239 415 Gene3D G3DSA:3.90.1150.10 274 414 1.8E-64 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS13540 2c65100a1f12dab3c2e9ebf636358fbe 442 Pfam PF02803 Thiolase, C-terminal domain 311 436 6.4E-31 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CDC59_RS13540 2c65100a1f12dab3c2e9ebf636358fbe 442 Gene3D G3DSA:3.40.47.10 283 434 2.1E-27 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS13540 2c65100a1f12dab3c2e9ebf636358fbe 442 Gene3D G3DSA:3.40.47.10 7 282 2.3E-41 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS13540 2c65100a1f12dab3c2e9ebf636358fbe 442 Pfam PF00108 Thiolase, N-terminal domain 10 279 3.1E-49 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CDC59_RS13540 2c65100a1f12dab3c2e9ebf636358fbe 442 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 12 435 4.5E-114 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CDC59_RS13540 2c65100a1f12dab3c2e9ebf636358fbe 442 SUPERFAMILY SSF53901 10 286 1.36E-57 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS13540 2c65100a1f12dab3c2e9ebf636358fbe 442 PIRSF PIRSF000429 5 438 2.7E-106 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CDC59_RS13540 2c65100a1f12dab3c2e9ebf636358fbe 442 SUPERFAMILY SSF53901 313 436 2.47E-30 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS08230 06a27a98718ace70a3a515244603239f 863 Hamap MF_01895 Ribonuclease R [rnr]. 28 743 56.542 T 29-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 CDC59_RS08230 06a27a98718ace70a3a515244603239f 863 TIGRFAM TIGR02063 RNase_R: ribonuclease R 9 585 3.9E-209 T 29-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 CDC59_RS08230 06a27a98718ace70a3a515244603239f 863 SUPERFAMILY SSF50249 527 582 1.4E-141 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDC59_RS08230 06a27a98718ace70a3a515244603239f 863 SUPERFAMILY SSF50249 620 660 1.4E-141 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDC59_RS08230 06a27a98718ace70a3a515244603239f 863 SUPERFAMILY SSF50249 176 491 1.4E-141 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDC59_RS08230 06a27a98718ace70a3a515244603239f 863 ProSitePatterns PS01175 Ribonuclease II family signature. 548 572 - T 29-03-2018 IPR022966 Ribonuclease II/R, conserved site CDC59_RS08230 06a27a98718ace70a3a515244603239f 863 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 63 743 4.4E-212 T 29-03-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 CDC59_RS08230 06a27a98718ace70a3a515244603239f 863 Pfam PF00575 S1 RNA binding domain 659 740 7.9E-12 T 29-03-2018 IPR003029 S1 domain GO:0003676 CDC59_RS08230 06a27a98718ace70a3a515244603239f 863 Pfam PF00773 RNB domain 249 580 9.6E-104 T 29-03-2018 CDC59_RS08230 06a27a98718ace70a3a515244603239f 863 SMART SM00955 249 581 6.1E-183 T 29-03-2018 CDC59_RS08230 06a27a98718ace70a3a515244603239f 863 Gene3D G3DSA:2.40.50.140 659 744 5.3E-18 T 29-03-2018 CDC59_RS08230 06a27a98718ace70a3a515244603239f 863 SMART SM00357 75 134 7.0E-10 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 CDC59_RS08230 06a27a98718ace70a3a515244603239f 863 Gene3D G3DSA:1.10.10.10 8 62 4.2E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS08230 06a27a98718ace70a3a515244603239f 863 SUPERFAMILY SSF50249 57 136 8.31E-19 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDC59_RS08230 06a27a98718ace70a3a515244603239f 863 Pfam PF08206 Ribonuclease B OB domain 76 133 6.1E-23 T 29-03-2018 IPR013223 Ribonuclease B, N-terminal OB domain CDC59_RS08230 06a27a98718ace70a3a515244603239f 863 Gene3D G3DSA:2.40.50.140 63 201 0.0019 T 29-03-2018 CDC59_RS08230 06a27a98718ace70a3a515244603239f 863 SMART SM00316 660 743 8.8E-13 T 29-03-2018 IPR022967 RNA-binding domain, S1 CDC59_RS08230 06a27a98718ace70a3a515244603239f 863 SMART SM00316 69 131 23.0 T 29-03-2018 IPR022967 RNA-binding domain, S1 CDC59_RS08230 06a27a98718ace70a3a515244603239f 863 SUPERFAMILY SSF50249 662 742 2.57E-20 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDC59_RS10145 2ff530a32f26e4edb497d4e7de00930d 230 ProSitePatterns PS00761 Signal peptidases I signature 3. 177 190 - T 29-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 CDC59_RS10145 2ff530a32f26e4edb497d4e7de00930d 230 Pfam PF10502 Signal peptidase, peptidase S26 170 208 4.7E-6 T 29-03-2018 IPR019533 Peptidase S26 CDC59_RS10145 2ff530a32f26e4edb497d4e7de00930d 230 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 93 105 1.2E-17 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CDC59_RS10145 2ff530a32f26e4edb497d4e7de00930d 230 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 172 191 1.2E-17 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CDC59_RS10145 2ff530a32f26e4edb497d4e7de00930d 230 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 30 46 1.2E-17 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CDC59_RS10145 2ff530a32f26e4edb497d4e7de00930d 230 ProSitePatterns PS00501 Signal peptidases I serine active site. 39 46 - T 29-03-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 CDC59_RS10145 2ff530a32f26e4edb497d4e7de00930d 230 SUPERFAMILY SSF51306 28 228 9.42E-59 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CDC59_RS10145 2ff530a32f26e4edb497d4e7de00930d 230 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 17 212 1.1E-44 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CDC59_RS10145 2ff530a32f26e4edb497d4e7de00930d 230 Pfam PF00717 Peptidase S24-like 37 116 1.5E-19 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CDC59_RS10145 2ff530a32f26e4edb497d4e7de00930d 230 ProSitePatterns PS00760 Signal peptidases I lysine active site. 95 107 - T 29-03-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 CDC59_RS10145 2ff530a32f26e4edb497d4e7de00930d 230 Gene3D G3DSA:2.10.109.10 26 227 6.4E-45 T 29-03-2018 CDC59_RS00885 07fed62ddaf65297a66b9fb40a14f5d0 353 Gene3D G3DSA:3.40.190.10 109 276 1.8E-45 T 29-03-2018 CDC59_RS00885 07fed62ddaf65297a66b9fb40a14f5d0 353 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 25 327 7.1E-89 T 29-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 CDC59_RS00885 07fed62ddaf65297a66b9fb40a14f5d0 353 Pfam PF12849 PBP superfamily domain 21 302 2.5E-49 T 29-03-2018 IPR024370 PBP domain CDC59_RS00885 07fed62ddaf65297a66b9fb40a14f5d0 353 SUPERFAMILY SSF53850 24 335 2.75E-82 T 29-03-2018 CDC59_RS00885 07fed62ddaf65297a66b9fb40a14f5d0 353 Gene3D G3DSA:3.40.190.10 19 108 3.3E-5 T 29-03-2018 CDC59_RS00885 07fed62ddaf65297a66b9fb40a14f5d0 353 PIRSF PIRSF002756 7 337 2.2E-81 T 29-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 CDC59_RS12710 ea8874911b3da39e148147fcbc9d8dee 328 Pfam PF05598 Transposase domain (DUF772) 51 126 6.0E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS12710 ea8874911b3da39e148147fcbc9d8dee 328 Pfam PF01609 Transposase DDE domain 138 312 2.4E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS13070 ea8874911b3da39e148147fcbc9d8dee 328 Pfam PF05598 Transposase domain (DUF772) 51 126 6.0E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS13070 ea8874911b3da39e148147fcbc9d8dee 328 Pfam PF01609 Transposase DDE domain 138 312 2.4E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS22665 ea8874911b3da39e148147fcbc9d8dee 328 Pfam PF05598 Transposase domain (DUF772) 51 126 6.0E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS22665 ea8874911b3da39e148147fcbc9d8dee 328 Pfam PF01609 Transposase DDE domain 138 312 2.4E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS16780 ea8874911b3da39e148147fcbc9d8dee 328 Pfam PF05598 Transposase domain (DUF772) 51 126 6.0E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS16780 ea8874911b3da39e148147fcbc9d8dee 328 Pfam PF01609 Transposase DDE domain 138 312 2.4E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS16705 ea8874911b3da39e148147fcbc9d8dee 328 Pfam PF05598 Transposase domain (DUF772) 51 126 6.0E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS16705 ea8874911b3da39e148147fcbc9d8dee 328 Pfam PF01609 Transposase DDE domain 138 312 2.4E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS13020 ea8874911b3da39e148147fcbc9d8dee 328 Pfam PF05598 Transposase domain (DUF772) 51 126 6.0E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS13020 ea8874911b3da39e148147fcbc9d8dee 328 Pfam PF01609 Transposase DDE domain 138 312 2.4E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS05375 ea8874911b3da39e148147fcbc9d8dee 328 Pfam PF05598 Transposase domain (DUF772) 51 126 6.0E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS05375 ea8874911b3da39e148147fcbc9d8dee 328 Pfam PF01609 Transposase DDE domain 138 312 2.4E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS01810 ea8874911b3da39e148147fcbc9d8dee 328 Pfam PF05598 Transposase domain (DUF772) 51 126 6.0E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS01810 ea8874911b3da39e148147fcbc9d8dee 328 Pfam PF01609 Transposase DDE domain 138 312 2.4E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS18440 059cf67a829b6933d731fd60eecd191c 407 Gene3D G3DSA:1.20.1250.20 202 407 2.7E-13 T 29-03-2018 CDC59_RS18440 059cf67a829b6933d731fd60eecd191c 407 SUPERFAMILY SSF103473 7 401 3.01E-22 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS18440 059cf67a829b6933d731fd60eecd191c 407 Gene3D G3DSA:1.20.1250.20 4 197 1.1E-4 T 29-03-2018 CDC59_RS08395 d7836ed4c6fa843a4386e24110f5e89b 272 Gene3D G3DSA:3.40.980.10 1 177 3.6E-42 T 29-03-2018 IPR001453 MoaB/Mog domain CDC59_RS08395 d7836ed4c6fa843a4386e24110f5e89b 272 Pfam PF00994 Probable molybdopterin binding domain 4 170 4.0E-26 T 29-03-2018 IPR001453 MoaB/Mog domain CDC59_RS08395 d7836ed4c6fa843a4386e24110f5e89b 272 SMART SM00852 4 177 1.9E-30 T 29-03-2018 IPR001453 MoaB/Mog domain CDC59_RS08395 d7836ed4c6fa843a4386e24110f5e89b 272 SUPERFAMILY SSF53218 2 211 1.22E-34 T 29-03-2018 IPR001453 MoaB/Mog domain CDC59_RS10495 5d381d9f646378ef0714939e3e23f633 896 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 14 895 0.0 T 29-03-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 CDC59_RS10495 5d381d9f646378ef0714939e3e23f633 896 Gene3D G3DSA:3.40.50.970 64 477 7.5E-83 T 29-03-2018 CDC59_RS10495 5d381d9f646378ef0714939e3e23f633 896 SUPERFAMILY SSF52518 65 473 1.23E-135 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CDC59_RS10495 5d381d9f646378ef0714939e3e23f633 896 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 91 303 2.9E-8 T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CDC59_RS10495 5d381d9f646378ef0714939e3e23f633 896 Gene3D G3DSA:3.40.50.970 478 712 6.2E-66 T 29-03-2018 CDC59_RS10495 5d381d9f646378ef0714939e3e23f633 896 SUPERFAMILY SSF52518 479 706 2.12E-97 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CDC59_RS10495 5d381d9f646378ef0714939e3e23f633 896 SUPERFAMILY SSF52922 711 895 2.35E-56 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CDC59_RS10495 5d381d9f646378ef0714939e3e23f633 896 Gene3D G3DSA:3.40.50.920 713 896 1.9E-37 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CDC59_RS10495 5d381d9f646378ef0714939e3e23f633 896 PIRSF PIRSF000156 5 896 0.0 T 29-03-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 CDC59_RS16230 3dab344e5d106ba1f40baaeea9ac98c0 104 TIGRFAM TIGR02683 upstrm_HI1419: putative addiction module killer protein 3 93 1.3E-31 T 29-03-2018 IPR014056 Addiction module killer protein, predicted CDC59_RS16230 3dab344e5d106ba1f40baaeea9ac98c0 104 PIRSF PIRSF028744 1 99 4.9E-31 T 29-03-2018 IPR014056 Addiction module killer protein, predicted CDC59_RS16230 3dab344e5d106ba1f40baaeea9ac98c0 104 Pfam PF05973 Phage derived protein Gp49-like (DUF891) 19 91 3.4E-8 T 29-03-2018 IPR009241 Toxin HigB-like CDC59_RS08080 854bda9537a8bb743e912fee1392545f 270 Pfam PF00005 ABC transporter 29 167 5.8E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS08080 854bda9537a8bb743e912fee1392545f 270 SUPERFAMILY SSF52540 22 229 6.31E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS08080 854bda9537a8bb743e912fee1392545f 270 SMART SM00382 37 217 3.2E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS08080 854bda9537a8bb743e912fee1392545f 270 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS08080 854bda9537a8bb743e912fee1392545f 270 Gene3D G3DSA:3.40.50.300 1 220 8.4E-61 T 29-03-2018 CDC59_RS06370 d2a5b259889ae99af81492a4c51add4d 407 Gene3D G3DSA:1.20.1250.20 7 205 5.7E-28 T 29-03-2018 CDC59_RS06370 d2a5b259889ae99af81492a4c51add4d 407 Pfam PF07690 Major Facilitator Superfamily 28 369 1.2E-36 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDC59_RS06370 d2a5b259889ae99af81492a4c51add4d 407 SUPERFAMILY SSF103473 9 397 4.19E-61 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS06370 d2a5b259889ae99af81492a4c51add4d 407 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 22 393 1.2E-90 T 29-03-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 CDC59_RS06370 d2a5b259889ae99af81492a4c51add4d 407 Gene3D G3DSA:1.20.1250.20 209 400 3.1E-16 T 29-03-2018 CDC59_RS07750 5e8742b34b1ef2d301fd905ac15f8189 207 Gene3D G3DSA:3.90.870.10 1 206 1.0E-58 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CDC59_RS07750 5e8742b34b1ef2d301fd905ac15f8189 207 SUPERFAMILY SSF55821 1 202 1.01E-60 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CDC59_RS07750 5e8742b34b1ef2d301fd905ac15f8189 207 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 7 200 2.2E-57 T 29-03-2018 IPR006070 YrdC-like domain GO:0003725 CDC59_RS07750 5e8742b34b1ef2d301fd905ac15f8189 207 Pfam PF01300 Telomere recombination 22 198 5.3E-44 T 29-03-2018 IPR006070 YrdC-like domain GO:0003725 CDC59_RS22300 a53258875e3117c4d15939b664d67298 249 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS22300 a53258875e3117c4d15939b664d67298 249 SMART SM00382 28 224 5.0E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS22300 a53258875e3117c4d15939b664d67298 249 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 224 246 1.8E-9 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CDC59_RS22300 a53258875e3117c4d15939b664d67298 249 Gene3D G3DSA:3.40.50.300 1 249 2.3E-60 T 29-03-2018 CDC59_RS22300 a53258875e3117c4d15939b664d67298 249 SUPERFAMILY SSF52540 3 244 2.19E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS22300 a53258875e3117c4d15939b664d67298 249 Pfam PF00005 ABC transporter 20 175 9.0E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS03475 f8f49bbca0be09f0b99615f6dcc30eb3 234 SUPERFAMILY SSF53955 56 218 2.64E-56 T 29-03-2018 IPR023346 Lysozyme-like domain CDC59_RS03475 f8f49bbca0be09f0b99615f6dcc30eb3 234 Pfam PF00912 Transglycosylase 59 226 2.9E-52 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 CDC59_RS03475 f8f49bbca0be09f0b99615f6dcc30eb3 234 Gene3D G3DSA:1.10.3810.10 51 232 4.3E-56 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 CDC59_RS03475 f8f49bbca0be09f0b99615f6dcc30eb3 234 Hamap MF_00766 Monofunctional biosynthetic peptidoglycan transglycosylase [mtgA]. 4 233 39.378 T 29-03-2018 IPR011812 Biosynthetic peptidoglycan transglycosylase GO:0009252|GO:0009274|GO:0016021|GO:0016763 CDC59_RS03475 f8f49bbca0be09f0b99615f6dcc30eb3 234 TIGRFAM TIGR02070 mono_pep_trsgly: monofunctional biosynthetic peptidoglycan transglycosylase 7 232 7.1E-106 T 29-03-2018 IPR011812 Biosynthetic peptidoglycan transglycosylase GO:0009252|GO:0009274|GO:0016021|GO:0016763 CDC59_RS21565 27a4a4143ed332b2c68a68d98df51281 262 SUPERFAMILY SSF56784 25 254 1.84E-45 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS21565 27a4a4143ed332b2c68a68d98df51281 262 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 26 221 4.6E-22 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CDC59_RS21565 27a4a4143ed332b2c68a68d98df51281 262 Pfam PF02358 Trehalose-phosphatase 27 241 7.9E-49 T 29-03-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 CDC59_RS21565 27a4a4143ed332b2c68a68d98df51281 262 TIGRFAM TIGR00685 T6PP: trehalose-phosphatase 23 254 2.3E-57 T 29-03-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 CDC59_RS21565 27a4a4143ed332b2c68a68d98df51281 262 Gene3D G3DSA:3.40.50.1000 23 259 1.0E-26 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS15770 bd7c5108ce3d3a17471341e01dff6c20 327 Gene3D G3DSA:3.10.25.10 220 327 1.5E-29 T 29-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CDC59_RS15770 bd7c5108ce3d3a17471341e01dff6c20 327 Pfam PF02911 Formyl transferase, C-terminal domain 217 315 2.0E-24 T 29-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CDC59_RS15770 bd7c5108ce3d3a17471341e01dff6c20 327 Pfam PF00551 Formyl transferase 6 193 9.4E-43 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CDC59_RS15770 bd7c5108ce3d3a17471341e01dff6c20 327 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 5 318 35.22 T 29-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 CDC59_RS15770 bd7c5108ce3d3a17471341e01dff6c20 327 SUPERFAMILY SSF53328 5 217 8.5E-62 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CDC59_RS15770 bd7c5108ce3d3a17471341e01dff6c20 327 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 5 321 1.4E-85 T 29-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 CDC59_RS15770 bd7c5108ce3d3a17471341e01dff6c20 327 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 145 168 - T 29-03-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CDC59_RS15770 bd7c5108ce3d3a17471341e01dff6c20 327 SUPERFAMILY SSF50486 218 323 3.53E-30 T 29-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 CDC59_RS15770 bd7c5108ce3d3a17471341e01dff6c20 327 Gene3D G3DSA:3.40.50.170 2 219 2.8E-68 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CDC59_RS20410 9780c4621b3afd9d7e3f0cbfb2b08254 258 SUPERFAMILY SSF51735 8 256 4.79E-82 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS20410 9780c4621b3afd9d7e3f0cbfb2b08254 258 Pfam PF00106 short chain dehydrogenase 15 205 6.6E-61 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS20410 9780c4621b3afd9d7e3f0cbfb2b08254 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 2.2E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS20410 9780c4621b3afd9d7e3f0cbfb2b08254 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 136 152 2.2E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS20410 9780c4621b3afd9d7e3f0cbfb2b08254 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 2.2E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS20410 9780c4621b3afd9d7e3f0cbfb2b08254 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 2.2E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS20410 9780c4621b3afd9d7e3f0cbfb2b08254 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 2.2E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS20410 9780c4621b3afd9d7e3f0cbfb2b08254 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 2.2E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS20410 9780c4621b3afd9d7e3f0cbfb2b08254 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 150 4.5E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS20410 9780c4621b3afd9d7e3f0cbfb2b08254 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 4.5E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS20410 9780c4621b3afd9d7e3f0cbfb2b08254 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 89 100 4.5E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS20410 9780c4621b3afd9d7e3f0cbfb2b08254 258 Gene3D G3DSA:3.40.50.720 2 257 4.9E-76 T 29-03-2018 CDC59_RS20410 9780c4621b3afd9d7e3f0cbfb2b08254 258 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 14 183 0.0087 T 29-03-2018 CDC59_RS20410 9780c4621b3afd9d7e3f0cbfb2b08254 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 149 177 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CDC59_RS19930 0fd7b195c648fabbdcf257f5f78f278a 663 SUPERFAMILY SSF55073 205 371 5.65E-40 T 29-03-2018 IPR029787 Nucleotide cyclase CDC59_RS19930 0fd7b195c648fabbdcf257f5f78f278a 663 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 196 368 2.3E-35 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS19930 0fd7b195c648fabbdcf257f5f78f278a 663 Pfam PF17152 Periplasmic sensor domain 44 148 2.9E-17 T 29-03-2018 IPR033417 Periplasmic sensor domain CHASE8 CDC59_RS19930 0fd7b195c648fabbdcf257f5f78f278a 663 Gene3D G3DSA:3.20.20.450 378 648 3.5E-107 T 29-03-2018 IPR001633 EAL domain CDC59_RS19930 0fd7b195c648fabbdcf257f5f78f278a 663 SMART SM00267 188 370 3.4E-50 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS19930 0fd7b195c648fabbdcf257f5f78f278a 663 Gene3D G3DSA:3.30.70.270 193 377 3.7E-55 T 29-03-2018 CDC59_RS19930 0fd7b195c648fabbdcf257f5f78f278a 663 Pfam PF00990 Diguanylate cyclase, GGDEF domain 199 365 5.6E-42 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS19930 0fd7b195c648fabbdcf257f5f78f278a 663 Pfam PF00563 EAL domain 386 629 2.8E-70 T 29-03-2018 IPR001633 EAL domain CDC59_RS19930 0fd7b195c648fabbdcf257f5f78f278a 663 SMART SM00052 380 634 1.7E-120 T 29-03-2018 IPR001633 EAL domain CDC59_RS19930 0fd7b195c648fabbdcf257f5f78f278a 663 SUPERFAMILY SSF141868 385 641 2.75E-90 T 29-03-2018 IPR001633 EAL domain CDC59_RS21615 8a501127db8d9f8f88df7a4f7c068a9b 1068 Pfam PF00873 AcrB/AcrD/AcrF family 3 1036 0.0 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS21615 8a501127db8d9f8f88df7a4f7c068a9b 1068 SUPERFAMILY SSF82693 41 134 8.55E-26 T 29-03-2018 CDC59_RS21615 8a501127db8d9f8f88df7a4f7c068a9b 1068 SUPERFAMILY SSF82866 842 1036 3.4E-44 T 29-03-2018 CDC59_RS21615 8a501127db8d9f8f88df7a4f7c068a9b 1068 SUPERFAMILY SSF82693 818 867 2.77E-28 T 29-03-2018 CDC59_RS21615 8a501127db8d9f8f88df7a4f7c068a9b 1068 SUPERFAMILY SSF82693 682 731 2.77E-28 T 29-03-2018 CDC59_RS21615 8a501127db8d9f8f88df7a4f7c068a9b 1068 Gene3D G3DSA:3.30.70.1320 777 856 5.9E-6 T 29-03-2018 CDC59_RS21615 8a501127db8d9f8f88df7a4f7c068a9b 1068 SUPERFAMILY SSF82714 732 818 1.11E-19 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS21615 8a501127db8d9f8f88df7a4f7c068a9b 1068 SUPERFAMILY SSF82693 138 184 3.35E-28 T 29-03-2018 CDC59_RS21615 8a501127db8d9f8f88df7a4f7c068a9b 1068 SUPERFAMILY SSF82693 277 333 3.35E-28 T 29-03-2018 CDC59_RS21615 8a501127db8d9f8f88df7a4f7c068a9b 1068 Gene3D G3DSA:1.20.1640.10 857 1050 1.0E-39 T 29-03-2018 CDC59_RS21615 8a501127db8d9f8f88df7a4f7c068a9b 1068 SUPERFAMILY SSF82866 299 499 3.79E-55 T 29-03-2018 CDC59_RS21615 8a501127db8d9f8f88df7a4f7c068a9b 1068 Gene3D G3DSA:3.30.70.1430 40 142 2.4E-25 T 29-03-2018 CDC59_RS21615 8a501127db8d9f8f88df7a4f7c068a9b 1068 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 3 1049 0.0 T 29-03-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 CDC59_RS21615 8a501127db8d9f8f88df7a4f7c068a9b 1068 Gene3D G3DSA:3.30.70.1430 577 678 1.1E-18 T 29-03-2018 CDC59_RS21615 8a501127db8d9f8f88df7a4f7c068a9b 1068 Gene3D G3DSA:1.20.1640.10 279 501 2.6E-54 T 29-03-2018 CDC59_RS21615 8a501127db8d9f8f88df7a4f7c068a9b 1068 Gene3D G3DSA:3.30.2090.10 183 278 3.7E-16 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS21615 8a501127db8d9f8f88df7a4f7c068a9b 1068 SUPERFAMILY SSF82714 185 273 6.28E-20 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS21615 8a501127db8d9f8f88df7a4f7c068a9b 1068 PRINTS PR00702 Acriflavin resistance protein family signature 394 418 1.7E-91 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS21615 8a501127db8d9f8f88df7a4f7c068a9b 1068 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 1.7E-91 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS21615 8a501127db8d9f8f88df7a4f7c068a9b 1068 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 1.7E-91 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS21615 8a501127db8d9f8f88df7a4f7c068a9b 1068 PRINTS PR00702 Acriflavin resistance protein family signature 366 387 1.7E-91 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS21615 8a501127db8d9f8f88df7a4f7c068a9b 1068 PRINTS PR00702 Acriflavin resistance protein family signature 631 645 1.7E-91 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS21615 8a501127db8d9f8f88df7a4f7c068a9b 1068 PRINTS PR00702 Acriflavin resistance protein family signature 339 362 1.7E-91 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS21615 8a501127db8d9f8f88df7a4f7c068a9b 1068 PRINTS PR00702 Acriflavin resistance protein family signature 447 470 1.7E-91 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS21615 8a501127db8d9f8f88df7a4f7c068a9b 1068 PRINTS PR00702 Acriflavin resistance protein family signature 562 579 1.7E-91 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS21615 8a501127db8d9f8f88df7a4f7c068a9b 1068 PRINTS PR00702 Acriflavin resistance protein family signature 472 495 1.7E-91 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS21615 8a501127db8d9f8f88df7a4f7c068a9b 1068 Gene3D G3DSA:3.30.70.1440 682 776 6.6E-24 T 29-03-2018 CDC59_RS21615 8a501127db8d9f8f88df7a4f7c068a9b 1068 SUPERFAMILY SSF82693 575 681 3.56E-27 T 29-03-2018 CDC59_RS04390 53901699c682c4e8818f9203c5ead8bd 56 Pfam PF00301 Rubredoxin 6 51 7.5E-23 T 29-03-2018 IPR024935 Rubredoxin domain GO:0005506 CDC59_RS04390 53901699c682c4e8818f9203c5ead8bd 56 PIRSF PIRSF000071 2 56 7.8E-26 T 29-03-2018 IPR024922 Rubredoxin GO:0005506|GO:0009055 CDC59_RS04390 53901699c682c4e8818f9203c5ead8bd 56 ProSitePatterns PS00202 Rubredoxin signature. 35 45 - T 29-03-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 CDC59_RS04390 53901699c682c4e8818f9203c5ead8bd 56 SUPERFAMILY SSF57802 2 55 2.69E-23 T 29-03-2018 CDC59_RS04390 53901699c682c4e8818f9203c5ead8bd 56 Gene3D G3DSA:2.20.28.10 1 56 7.6E-26 T 29-03-2018 CDC59_RS04390 53901699c682c4e8818f9203c5ead8bd 56 PRINTS PR00163 Rubredoxin signature 5 21 3.5E-8 T 29-03-2018 IPR024935 Rubredoxin domain GO:0005506 CDC59_RS04390 53901699c682c4e8818f9203c5ead8bd 56 PRINTS PR00163 Rubredoxin signature 35 51 3.5E-8 T 29-03-2018 IPR024935 Rubredoxin domain GO:0005506 CDC59_RS22225 97062a51387e6e5d2ffb2cecbdb1f0ab 461 ProSitePatterns PS00163 Fumarate lyases signature. 316 325 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CDC59_RS22225 97062a51387e6e5d2ffb2cecbdb1f0ab 461 Pfam PF00206 Lyase 11 341 3.0E-113 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal CDC59_RS22225 97062a51387e6e5d2ffb2cecbdb1f0ab 461 Hamap MF_00743 Fumarate hydratase class II [fumC]. 3 461 92.634 T 29-03-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CDC59_RS22225 97062a51387e6e5d2ffb2cecbdb1f0ab 461 PRINTS PR00149 Fumarate lyase superfamily signature 133 151 2.9E-34 T 29-03-2018 IPR000362 Fumarate lyase family CDC59_RS22225 97062a51387e6e5d2ffb2cecbdb1f0ab 461 PRINTS PR00149 Fumarate lyase superfamily signature 270 297 2.9E-34 T 29-03-2018 IPR000362 Fumarate lyase family CDC59_RS22225 97062a51387e6e5d2ffb2cecbdb1f0ab 461 PRINTS PR00149 Fumarate lyase superfamily signature 316 332 2.9E-34 T 29-03-2018 IPR000362 Fumarate lyase family CDC59_RS22225 97062a51387e6e5d2ffb2cecbdb1f0ab 461 PRINTS PR00149 Fumarate lyase superfamily signature 179 197 2.9E-34 T 29-03-2018 IPR000362 Fumarate lyase family CDC59_RS22225 97062a51387e6e5d2ffb2cecbdb1f0ab 461 Pfam PF10415 Fumarase C C-terminus 407 460 2.5E-27 T 29-03-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CDC59_RS22225 97062a51387e6e5d2ffb2cecbdb1f0ab 461 Gene3D G3DSA:1.10.275.10 1 137 1.8E-61 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal CDC59_RS22225 97062a51387e6e5d2ffb2cecbdb1f0ab 461 Gene3D G3DSA:1.10.40.30 418 458 2.6E-27 T 29-03-2018 CDC59_RS22225 97062a51387e6e5d2ffb2cecbdb1f0ab 461 Gene3D G3DSA:1.20.200.10 138 417 1.8E-89 T 29-03-2018 CDC59_RS22225 97062a51387e6e5d2ffb2cecbdb1f0ab 461 TIGRFAM TIGR00979 fumC_II: fumarate hydratase, class II 4 460 6.7E-236 T 29-03-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CDC59_RS22225 97062a51387e6e5d2ffb2cecbdb1f0ab 461 SUPERFAMILY SSF48557 3 461 5.18E-160 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 CDC59_RS03860 3f04b4ccd53fdddda621c24934842355 274 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 8 267 8.4E-76 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CDC59_RS03860 3f04b4ccd53fdddda621c24934842355 274 Gene3D G3DSA:1.10.3730.10 165 272 4.6E-35 T 29-03-2018 CDC59_RS03860 3f04b4ccd53fdddda621c24934842355 274 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 222 245 - T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CDC59_RS03860 3f04b4ccd53fdddda621c24934842355 274 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 6 99 4.7E-19 T 29-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal CDC59_RS03860 3f04b4ccd53fdddda621c24934842355 274 SUPERFAMILY SSF51735 6 160 1.44E-35 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS03860 3f04b4ccd53fdddda621c24934842355 274 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 163 267 1.6E-32 T 29-03-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 CDC59_RS03860 3f04b4ccd53fdddda621c24934842355 274 Gene3D G3DSA:3.40.50.720 2 164 7.9E-32 T 29-03-2018 CDC59_RS03860 3f04b4ccd53fdddda621c24934842355 274 PIRSF PIRSF000193 4 270 5.0E-71 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CDC59_RS03860 3f04b4ccd53fdddda621c24934842355 274 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 5 267 26.417 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CDC59_RS03860 3f04b4ccd53fdddda621c24934842355 274 SUPERFAMILY SSF48179 163 270 7.48E-33 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CDC59_RS04895 5847e54143d177bc25b35caa7493db94 355 SUPERFAMILY SSF117396 55 346 3.53E-47 T 29-03-2018 IPR002763 Protein of unknown function DUF72 CDC59_RS04895 5847e54143d177bc25b35caa7493db94 355 Gene3D G3DSA:3.20.20.410 43 355 4.5E-56 T 29-03-2018 IPR002763 Protein of unknown function DUF72 CDC59_RS04895 5847e54143d177bc25b35caa7493db94 355 Pfam PF01904 Protein of unknown function DUF72 76 344 6.8E-38 T 29-03-2018 IPR002763 Protein of unknown function DUF72 CDC59_RS14795 c980582561e3efa66e66726cbbfbda41 66 Gene3D G3DSA:3.20.20.30 2 66 6.4E-9 T 29-03-2018 CDC59_RS14795 c980582561e3efa66e66726cbbfbda41 66 SUPERFAMILY SSF51679 5 58 1.96E-9 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CDC59_RS06205 9d9bb9e1197e67f5866e5a0ff7cbe9a6 282 SMART SM00450 118 219 1.4E-7 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS06205 9d9bb9e1197e67f5866e5a0ff7cbe9a6 282 Hamap MF_00469 UPF0176 protein YceA [yceA]. 1 257 37.742 T 29-03-2018 IPR020936 Uncharacterised protein family UPF0176 CDC59_RS06205 9d9bb9e1197e67f5866e5a0ff7cbe9a6 282 SUPERFAMILY SSF52821 95 234 2.74E-24 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS06205 9d9bb9e1197e67f5866e5a0ff7cbe9a6 282 Gene3D G3DSA:3.40.250.10 106 225 2.2E-17 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS15780 a0552463ca2f750ef41ceb47a6298cb3 169 PRINTS PR01576 Peptide deformylase signature 102 120 7.4E-37 T 29-03-2018 IPR023635 Peptide deformylase CDC59_RS15780 a0552463ca2f750ef41ceb47a6298cb3 169 PRINTS PR01576 Peptide deformylase signature 121 150 7.4E-37 T 29-03-2018 IPR023635 Peptide deformylase CDC59_RS15780 a0552463ca2f750ef41ceb47a6298cb3 169 PRINTS PR01576 Peptide deformylase signature 33 62 7.4E-37 T 29-03-2018 IPR023635 Peptide deformylase CDC59_RS15780 a0552463ca2f750ef41ceb47a6298cb3 169 PRINTS PR01576 Peptide deformylase signature 90 101 7.4E-37 T 29-03-2018 IPR023635 Peptide deformylase CDC59_RS15780 a0552463ca2f750ef41ceb47a6298cb3 169 PIRSF PIRSF004749 1 169 1.5E-57 T 29-03-2018 IPR023635 Peptide deformylase CDC59_RS15780 a0552463ca2f750ef41ceb47a6298cb3 169 Gene3D G3DSA:3.90.45.10 1 169 3.9E-63 T 29-03-2018 IPR023635 Peptide deformylase CDC59_RS15780 a0552463ca2f750ef41ceb47a6298cb3 169 Pfam PF01327 Polypeptide deformylase 4 153 1.2E-51 T 29-03-2018 IPR023635 Peptide deformylase CDC59_RS15780 a0552463ca2f750ef41ceb47a6298cb3 169 SUPERFAMILY SSF56420 3 165 1.19E-61 T 29-03-2018 IPR023635 Peptide deformylase CDC59_RS15780 a0552463ca2f750ef41ceb47a6298cb3 169 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 4 161 2.3E-56 T 29-03-2018 IPR023635 Peptide deformylase CDC59_RS15780 a0552463ca2f750ef41ceb47a6298cb3 169 Hamap MF_00163 Peptide deformylase [def]. 2 163 30.469 T 29-03-2018 IPR023635 Peptide deformylase CDC59_RS06095 b618452df482599df9a1e8116a8eeb13 268 Pfam PF02535 ZIP Zinc transporter 98 259 5.9E-32 T 29-03-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 CDC59_RS20490 f0f30f3df1eafdf84454d48bbcae7dc7 280 Gene3D G3DSA:3.40.190.10 23 151 5.8E-30 T 29-03-2018 CDC59_RS20490 f0f30f3df1eafdf84454d48bbcae7dc7 280 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 37 255 1.4E-49 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CDC59_RS20490 f0f30f3df1eafdf84454d48bbcae7dc7 280 SUPERFAMILY SSF53850 10 256 1.54E-56 T 29-03-2018 CDC59_RS20490 f0f30f3df1eafdf84454d48bbcae7dc7 280 Gene3D G3DSA:3.40.190.10 152 269 3.3E-13 T 29-03-2018 CDC59_RS20490 f0f30f3df1eafdf84454d48bbcae7dc7 280 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 60 73 - T 29-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 CDC59_RS20490 f0f30f3df1eafdf84454d48bbcae7dc7 280 SMART SM00062 36 257 3.1E-55 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CDC59_RS02500 6134d897acf91a3c242353b268b89005 241 Pfam PF01797 Transposase IS200 like 14 123 3.2E-16 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS02500 6134d897acf91a3c242353b268b89005 241 Gene3D G3DSA:3.30.70.1290 8 130 2.3E-22 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS02500 6134d897acf91a3c242353b268b89005 241 SMART SM01321 10 124 5.7E-35 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS02500 6134d897acf91a3c242353b268b89005 241 SUPERFAMILY SSF143422 3 127 2.09E-26 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS07560 aba741c18a8eba2840dc79098fcddbdd 418 SUPERFAMILY SSF48264 18 418 1.44E-60 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CDC59_RS07560 aba741c18a8eba2840dc79098fcddbdd 418 Pfam PF00067 Cytochrome P450 289 384 4.2E-16 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CDC59_RS07560 aba741c18a8eba2840dc79098fcddbdd 418 Gene3D G3DSA:1.10.630.10 1 417 4.8E-51 T 29-03-2018 CDC59_RS07560 aba741c18a8eba2840dc79098fcddbdd 418 PRINTS PR00359 B-class P450 signature 158 173 1.5E-35 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CDC59_RS07560 aba741c18a8eba2840dc79098fcddbdd 418 PRINTS PR00359 B-class P450 signature 334 349 1.5E-35 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CDC59_RS07560 aba741c18a8eba2840dc79098fcddbdd 418 PRINTS PR00359 B-class P450 signature 355 364 1.5E-35 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CDC59_RS07560 aba741c18a8eba2840dc79098fcddbdd 418 PRINTS PR00359 B-class P450 signature 95 106 1.5E-35 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CDC59_RS07560 aba741c18a8eba2840dc79098fcddbdd 418 PRINTS PR00359 B-class P450 signature 206 228 1.5E-35 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CDC59_RS07560 aba741c18a8eba2840dc79098fcddbdd 418 PRINTS PR00359 B-class P450 signature 289 300 1.5E-35 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CDC59_RS07560 aba741c18a8eba2840dc79098fcddbdd 418 PRINTS PR00359 B-class P450 signature 306 333 1.5E-35 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CDC59_RS07560 aba741c18a8eba2840dc79098fcddbdd 418 PRINTS PR00359 B-class P450 signature 364 375 1.5E-35 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CDC59_RS07560 aba741c18a8eba2840dc79098fcddbdd 418 PRINTS PR00359 B-class P450 signature 141 157 1.5E-35 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CDC59_RS13715 5be779871cc842ab502c9a2125450440 77 PIRSF PIRSF002097 1 77 6.9E-35 T 29-03-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 CDC59_RS13715 5be779871cc842ab502c9a2125450440 77 Gene3D G3DSA:1.10.10.60 1 76 4.7E-16 T 29-03-2018 CDC59_RS13715 5be779871cc842ab502c9a2125450440 77 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 40 57 1.9E-9 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CDC59_RS13715 5be779871cc842ab502c9a2125450440 77 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 57 77 1.9E-9 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CDC59_RS13715 5be779871cc842ab502c9a2125450440 77 SUPERFAMILY SSF46689 8 76 6.81E-20 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS13715 5be779871cc842ab502c9a2125450440 77 PRINTS PR01591 DNA-binding protein FIS signature 21 36 4.2E-6 T 29-03-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 CDC59_RS13715 5be779871cc842ab502c9a2125450440 77 PRINTS PR01591 DNA-binding protein FIS signature 36 48 4.2E-6 T 29-03-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 CDC59_RS13715 5be779871cc842ab502c9a2125450440 77 PRINTS PR01591 DNA-binding protein FIS signature 5 21 4.2E-6 T 29-03-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 CDC59_RS13715 5be779871cc842ab502c9a2125450440 77 Pfam PF02954 Bacterial regulatory protein, Fis family 34 74 3.5E-13 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CDC59_RS08250 832d3ed4f2f831aeea992758854711d4 228 SUPERFAMILY SSF75445 130 207 9.94E-23 T 29-03-2018 CDC59_RS08250 832d3ed4f2f831aeea992758854711d4 228 Gene3D G3DSA:3.40.50.1360 1 141 2.0E-39 T 29-03-2018 CDC59_RS08250 832d3ed4f2f831aeea992758854711d4 228 SUPERFAMILY SSF100950 1 150 2.76E-42 T 29-03-2018 CDC59_RS08250 832d3ed4f2f831aeea992758854711d4 228 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 3 226 32.683 T 29-03-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CDC59_RS08250 832d3ed4f2f831aeea992758854711d4 228 Gene3D G3DSA:3.30.70.260 142 205 2.3E-25 T 29-03-2018 CDC59_RS08250 832d3ed4f2f831aeea992758854711d4 228 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 53 222 8.9E-58 T 29-03-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CDC59_RS08250 832d3ed4f2f831aeea992758854711d4 228 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 12 223 8.1E-65 T 29-03-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CDC59_RS18455 a9c897b483cf6e3d7235ce941405e4eb 215 Gene3D G3DSA:3.30.1330.60 40 214 5.7E-33 T 29-03-2018 IPR006665 OmpA-like domain CDC59_RS18455 a9c897b483cf6e3d7235ce941405e4eb 215 Pfam PF00691 OmpA family 92 196 1.5E-18 T 29-03-2018 IPR006665 OmpA-like domain CDC59_RS18455 a9c897b483cf6e3d7235ce941405e4eb 215 SUPERFAMILY SSF103088 82 201 9.29E-27 T 29-03-2018 IPR006665 OmpA-like domain CDC59_RS04250 51adf06fef3adf3b2537966227db2b1e 88 Gene3D G3DSA:1.20.58.110 1 88 1.2E-25 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS04250 51adf06fef3adf3b2537966227db2b1e 88 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 85 4.4E-23 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS04250 51adf06fef3adf3b2537966227db2b1e 88 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 16.381 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS04250 51adf06fef3adf3b2537966227db2b1e 88 SUPERFAMILY SSF46992 3 86 1.12E-26 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS04250 51adf06fef3adf3b2537966227db2b1e 88 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 20 68 2.0E-7 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS04250 51adf06fef3adf3b2537966227db2b1e 88 Pfam PF01649 Ribosomal protein S20 2 84 1.9E-23 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS03865 fd8757fceb82f275269d3f63649b43ff 240 Pfam PF01168 Alanine racemase, N-terminal domain 7 233 1.4E-30 T 29-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CDC59_RS03865 fd8757fceb82f275269d3f63649b43ff 240 PIRSF PIRSF004848 1 239 4.5E-69 T 29-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein CDC59_RS03865 fd8757fceb82f275269d3f63649b43ff 240 Gene3D G3DSA:3.20.20.10 1 240 4.5E-74 T 29-03-2018 IPR029066 PLP-binding barrel CDC59_RS03865 fd8757fceb82f275269d3f63649b43ff 240 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 1 233 1.9E-68 T 29-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein CDC59_RS03865 fd8757fceb82f275269d3f63649b43ff 240 SUPERFAMILY SSF51419 3 231 7.33E-77 T 29-03-2018 IPR029066 PLP-binding barrel CDC59_RS03865 fd8757fceb82f275269d3f63649b43ff 240 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 81 95 - T 29-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein CDC59_RS10700 9cfaeb9045bf2825c0afbd2b4b9b7f36 65 PRINTS PR00064 Ribosomal protein L35 signature 21 35 8.5E-15 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CDC59_RS10700 9cfaeb9045bf2825c0afbd2b4b9b7f36 65 PRINTS PR00064 Ribosomal protein L35 signature 3 20 8.5E-15 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CDC59_RS10700 9cfaeb9045bf2825c0afbd2b4b9b7f36 65 PRINTS PR00064 Ribosomal protein L35 signature 36 54 8.5E-15 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CDC59_RS10700 9cfaeb9045bf2825c0afbd2b4b9b7f36 65 SUPERFAMILY SSF143034 2 64 3.92E-22 T 29-03-2018 CDC59_RS10700 9cfaeb9045bf2825c0afbd2b4b9b7f36 65 Pfam PF01632 Ribosomal protein L35 2 62 1.6E-22 T 29-03-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS10700 9cfaeb9045bf2825c0afbd2b4b9b7f36 65 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 64 1.6E-24 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CDC59_RS10700 9cfaeb9045bf2825c0afbd2b4b9b7f36 65 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 17.578 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CDC59_RS10700 9cfaeb9045bf2825c0afbd2b4b9b7f36 65 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 29-03-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS01735 8d5fcda64d4aa0459336fd50a1001646 153 TIGRFAM TIGR01708 typeII_sec_gspH: type II secretion system protein H 3 136 7.3E-22 T 29-03-2018 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 CDC59_RS01735 8d5fcda64d4aa0459336fd50a1001646 153 Pfam PF07963 Prokaryotic N-terminal methylation motif 2 24 1.3E-7 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS01735 8d5fcda64d4aa0459336fd50a1001646 153 SUPERFAMILY SSF54523 5 86 3.06E-13 T 29-03-2018 CDC59_RS01735 8d5fcda64d4aa0459336fd50a1001646 153 Gene3D G3DSA:3.55.40.10 34 153 8.9E-19 T 29-03-2018 CDC59_RS01735 8d5fcda64d4aa0459336fd50a1001646 153 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 2 24 3.0E-8 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS01735 8d5fcda64d4aa0459336fd50a1001646 153 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 3 23 - T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS01735 8d5fcda64d4aa0459336fd50a1001646 153 Pfam PF12019 Type II transport protein GspH 40 142 6.9E-7 T 29-03-2018 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 CDC59_RS10805 b4a5abc202eac6b007f01a3cbcc77493 197 Pfam PF03358 NADPH-dependent FMN reductase 11 141 7.3E-10 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CDC59_RS10805 b4a5abc202eac6b007f01a3cbcc77493 197 SUPERFAMILY SSF52218 1 195 2.88E-57 T 29-03-2018 IPR029039 Flavoprotein-like domain CDC59_RS10805 b4a5abc202eac6b007f01a3cbcc77493 197 TIGRFAM TIGR01755 flav_wrbA: NAD(P)H:quinone oxidoreductase, type IV 4 194 1.5E-42 T 29-03-2018 IPR010089 Flavoprotein WrbA-like GO:0003955|GO:0010181 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 CDC59_RS10805 b4a5abc202eac6b007f01a3cbcc77493 197 Gene3D G3DSA:3.40.50.360 1 197 3.1E-39 T 29-03-2018 IPR029039 Flavoprotein-like domain CDC59_RS10805 b4a5abc202eac6b007f01a3cbcc77493 197 ProSitePatterns PS00201 Flavodoxin signature. 6 22 - T 29-03-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 CDC59_RS03715 2cddfe96f83f87f29136f55d4c7acb13 322 Pfam PF02355 Protein export membrane protein 115 296 5.9E-63 T 29-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial CDC59_RS03715 2cddfe96f83f87f29136f55d4c7acb13 322 Pfam PF07549 SecD/SecF GG Motif 32 59 6.5E-8 T 29-03-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site CDC59_RS03715 2cddfe96f83f87f29136f55d4c7acb13 322 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 120 285 9.6E-48 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CDC59_RS03715 2cddfe96f83f87f29136f55d4c7acb13 322 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 38 288 3.1E-73 T 29-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 CDC59_RS03715 2cddfe96f83f87f29136f55d4c7acb13 322 Gene3D G3DSA:1.20.1640.10 100 309 1.2E-32 T 29-03-2018 CDC59_RS03715 2cddfe96f83f87f29136f55d4c7acb13 322 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 10 299 28.666 T 29-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 CDC59_RS03715 2cddfe96f83f87f29136f55d4c7acb13 322 SUPERFAMILY SSF82866 71 299 2.35E-39 T 29-03-2018 CDC59_RS03715 2cddfe96f83f87f29136f55d4c7acb13 322 PRINTS PR01755 Bacterial translocase SecF protein signature 37 52 1.3E-25 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CDC59_RS03715 2cddfe96f83f87f29136f55d4c7acb13 322 PRINTS PR01755 Bacterial translocase SecF protein signature 236 251 1.3E-25 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CDC59_RS03715 2cddfe96f83f87f29136f55d4c7acb13 322 PRINTS PR01755 Bacterial translocase SecF protein signature 204 222 1.3E-25 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CDC59_RS03715 2cddfe96f83f87f29136f55d4c7acb13 322 PRINTS PR01755 Bacterial translocase SecF protein signature 156 170 1.3E-25 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CDC59_RS01585 a09c10735909ce7db038a1e3d291fce3 987 SUPERFAMILY SSF51445 38 270 1.77E-14 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CDC59_RS01585 a09c10735909ce7db038a1e3d291fce3 987 Gene3D G3DSA:3.20.20.70 94 279 2.5E-19 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS01585 a09c10735909ce7db038a1e3d291fce3 987 Gene3D G3DSA:3.20.20.370 465 833 9.5E-14 T 29-03-2018 CDC59_RS01585 a09c10735909ce7db038a1e3d291fce3 987 PIRSF PIRSF029570 1 97 3.4E-27 T 29-03-2018 IPR016925 Uncharacterised conserved protein UCP029570 CDC59_RS01585 a09c10735909ce7db038a1e3d291fce3 987 PIRSF PIRSF029570 89 986 0.0 T 29-03-2018 IPR016925 Uncharacterised conserved protein UCP029570 CDC59_RS08190 951fa80dcb5c3cbf09f11383b81a6685 417 Gene3D G3DSA:3.40.50.300 171 378 4.7E-30 T 29-03-2018 CDC59_RS08190 951fa80dcb5c3cbf09f11383b81a6685 417 SUPERFAMILY SSF52540 202 377 2.8E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS08190 951fa80dcb5c3cbf09f11383b81a6685 417 Pfam PF16360 GTP-binding GTPase Middle Region 117 196 9.2E-25 T 29-03-2018 IPR032305 GTP-binding protein, middle domain CDC59_RS08190 951fa80dcb5c3cbf09f11383b81a6685 417 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 271 289 1.1E-7 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CDC59_RS08190 951fa80dcb5c3cbf09f11383b81a6685 417 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 204 224 1.1E-7 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CDC59_RS08190 951fa80dcb5c3cbf09f11383b81a6685 417 Pfam PF13167 GTP-binding GTPase N-terminal 28 114 4.5E-29 T 29-03-2018 IPR025121 GTPase HflX, N-terminal CDC59_RS08190 951fa80dcb5c3cbf09f11383b81a6685 417 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 13 366 5.2E-142 T 29-03-2018 IPR016496 GTPase HflX GO:0005525 CDC59_RS08190 951fa80dcb5c3cbf09f11383b81a6685 417 Pfam PF01926 50S ribosome-binding GTPase 204 322 4.5E-22 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CDC59_RS08190 951fa80dcb5c3cbf09f11383b81a6685 417 PIRSF PIRSF006809 5 375 6.2E-135 T 29-03-2018 IPR016496 GTPase HflX GO:0005525 CDC59_RS08190 951fa80dcb5c3cbf09f11383b81a6685 417 Hamap MF_00900 GTPase HflX [hflX]. 30 393 44.736 T 29-03-2018 IPR016496 GTPase HflX GO:0005525 CDC59_RS15540 5645e85cb487e3023fdf381d3bc1eedf 121 PIRSF PIRSF018634 6 121 4.2E-44 T 29-03-2018 IPR009387 Toxin HigB-2 CDC59_RS15540 5645e85cb487e3023fdf381d3bc1eedf 121 Pfam PF06296 RelE toxin of RelE / RelB toxin-antitoxin system 7 118 1.0E-32 T 29-03-2018 IPR009387 Toxin HigB-2 CDC59_RS12940 9e560409f11b3b6d9db77bee2b86cdfc 268 Pfam PF02348 Cytidylyltransferase 7 233 6.6E-54 T 29-03-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 CDC59_RS12940 9e560409f11b3b6d9db77bee2b86cdfc 268 Hamap MF_00057 8-amino-3,8-dideoxy-manno-octulosonate cytidylyltransferase [kdsB]. 4 260 41.1 T 29-03-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 CDC59_RS12940 9e560409f11b3b6d9db77bee2b86cdfc 268 SUPERFAMILY SSF53448 6 261 3.18E-59 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDC59_RS12940 9e560409f11b3b6d9db77bee2b86cdfc 268 TIGRFAM TIGR00466 kdsB: 3-deoxy-D-manno-octulosonate cytidylyltransferase 6 252 1.2E-87 T 29-03-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 CDC59_RS12940 9e560409f11b3b6d9db77bee2b86cdfc 268 Gene3D G3DSA:3.90.550.10 5 261 2.1E-48 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDC59_RS08300 cc56ebff3cf1dbd223382a78116477bf 86 TIGRFAM TIGR02683 upstrm_HI1419: putative addiction module killer protein 1 79 5.4E-31 T 29-03-2018 IPR014056 Addiction module killer protein, predicted CDC59_RS08300 cc56ebff3cf1dbd223382a78116477bf 86 Pfam PF05973 Phage derived protein Gp49-like (DUF891) 25 81 1.3E-5 T 29-03-2018 IPR009241 Toxin HigB-like CDC59_RS08300 cc56ebff3cf1dbd223382a78116477bf 86 PIRSF PIRSF028744 1 85 5.7E-31 T 29-03-2018 IPR014056 Addiction module killer protein, predicted CDC59_RS12835 d2bec231a75d4931913bca1aba06150f 267 Gene3D G3DSA:3.40.190.10 27 136 2.7E-27 T 29-03-2018 CDC59_RS12835 d2bec231a75d4931913bca1aba06150f 267 Gene3D G3DSA:3.40.190.10 137 215 1.1E-10 T 29-03-2018 CDC59_RS12835 d2bec231a75d4931913bca1aba06150f 267 SMART SM00062 37 261 1.6E-41 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CDC59_RS12835 d2bec231a75d4931913bca1aba06150f 267 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 38 258 3.6E-41 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CDC59_RS12835 d2bec231a75d4931913bca1aba06150f 267 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 61 74 - T 29-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 CDC59_RS12835 d2bec231a75d4931913bca1aba06150f 267 SUPERFAMILY SSF53850 8 260 3.3E-53 T 29-03-2018 CDC59_RS11210 b2275ee0c79aa6fc7ff52b2194b8abd6 155 Pfam PF01799 [2Fe-2S] binding domain 71 144 2.4E-24 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CDC59_RS11210 b2275ee0c79aa6fc7ff52b2194b8abd6 155 Gene3D G3DSA:1.10.150.120 73 155 8.6E-26 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CDC59_RS11210 b2275ee0c79aa6fc7ff52b2194b8abd6 155 Gene3D G3DSA:3.10.20.30 1 72 9.2E-27 T 29-03-2018 IPR012675 Beta-grasp domain CDC59_RS11210 b2275ee0c79aa6fc7ff52b2194b8abd6 155 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 37 45 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CDC59_RS11210 b2275ee0c79aa6fc7ff52b2194b8abd6 155 SUPERFAMILY SSF47741 83 151 1.83E-27 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CDC59_RS11210 b2275ee0c79aa6fc7ff52b2194b8abd6 155 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 4 57 6.2E-8 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CDC59_RS11210 b2275ee0c79aa6fc7ff52b2194b8abd6 155 SUPERFAMILY SSF54292 2 76 1.05E-25 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CDC59_RS11205 bf6eafafec7c4ca520110441aae02b14 765 Gene3D G3DSA:3.30.365.10 28 233 5.1E-42 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CDC59_RS11205 bf6eafafec7c4ca520110441aae02b14 765 PIRSF PIRSF036389 1 765 1.2E-264 T 29-03-2018 IPR012368 Oxidoreductase molybdopterin-binding subunit, IorB-related CDC59_RS11205 bf6eafafec7c4ca520110441aae02b14 765 Gene3D G3DSA:3.30.365.10 469 618 1.7E-34 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CDC59_RS11205 bf6eafafec7c4ca520110441aae02b14 765 SMART SM01008 248 332 4.6E-26 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CDC59_RS11205 bf6eafafec7c4ca520110441aae02b14 765 Gene3D G3DSA:3.30.365.10 619 765 3.0E-33 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CDC59_RS11205 bf6eafafec7c4ca520110441aae02b14 765 SUPERFAMILY SSF56003 357 764 1.14E-104 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CDC59_RS11205 bf6eafafec7c4ca520110441aae02b14 765 Gene3D G3DSA:3.90.1170.50 234 390 2.6E-27 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CDC59_RS11205 bf6eafafec7c4ca520110441aae02b14 765 SUPERFAMILY SSF56003 149 281 1.88E-36 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CDC59_RS11205 bf6eafafec7c4ca520110441aae02b14 765 SUPERFAMILY SSF56003 24 111 1.88E-36 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CDC59_RS11205 bf6eafafec7c4ca520110441aae02b14 765 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 641 719 2.6E-16 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CDC59_RS11205 bf6eafafec7c4ca520110441aae02b14 765 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 29 105 2.6E-8 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CDC59_RS11205 bf6eafafec7c4ca520110441aae02b14 765 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 360 596 1.4E-28 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CDC59_RS11205 bf6eafafec7c4ca520110441aae02b14 765 Gene3D G3DSA:3.30.365.10 391 468 1.4E-24 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CDC59_RS21640 6d81549964cdf2173198753228d2c465 296 Gene3D G3DSA:3.40.190.10 163 296 3.2E-19 T 29-03-2018 CDC59_RS21640 6d81549964cdf2173198753228d2c465 296 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 36 265 9.3E-48 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CDC59_RS21640 6d81549964cdf2173198753228d2c465 296 SUPERFAMILY SSF53850 6 268 1.09E-59 T 29-03-2018 CDC59_RS21640 6d81549964cdf2173198753228d2c465 296 SMART SM00062 35 267 2.4E-47 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CDC59_RS21640 6d81549964cdf2173198753228d2c465 296 Gene3D G3DSA:3.40.190.10 17 162 8.2E-25 T 29-03-2018 CDC59_RS06625 b085a0f33a1fcc268ce43f1a2006bb66 445 SUPERFAMILY SSF51338 32 94 7.2E-11 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CDC59_RS06625 b085a0f33a1fcc268ce43f1a2006bb66 445 TIGRFAM TIGR02967 guan_deamin: guanine deaminase 34 434 2.0E-176 T 29-03-2018 IPR014311 Guanine deaminase GO:0006147|GO:0008270|GO:0008892 KEGG: 00230+3.5.4.3|MetaCyc: PWY-5497|MetaCyc: PWY-6606|MetaCyc: PWY-6608|MetaCyc: PWY-7442|Reactome: R-HSA-74259 CDC59_RS06625 b085a0f33a1fcc268ce43f1a2006bb66 445 Gene3D G3DSA:2.30.40.10 2 87 4.9E-13 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CDC59_RS06625 b085a0f33a1fcc268ce43f1a2006bb66 445 SUPERFAMILY SSF51556 78 381 1.12E-95 T 29-03-2018 IPR032466 Metal-dependent hydrolase CDC59_RS06625 b085a0f33a1fcc268ce43f1a2006bb66 445 Pfam PF01979 Amidohydrolase family 76 435 2.8E-56 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CDC59_RS06625 b085a0f33a1fcc268ce43f1a2006bb66 445 SUPERFAMILY SSF51338 353 435 6.24E-11 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CDC59_RS06625 b085a0f33a1fcc268ce43f1a2006bb66 445 Gene3D G3DSA:3.20.20.140 88 380 1.9E-67 T 29-03-2018 CDC59_RS19110 369bdb84c31c0bd540cf398bf0e20d38 237 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 206 3.5E-24 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CDC59_RS19110 369bdb84c31c0bd540cf398bf0e20d38 237 SUPERFAMILY SSF53790 3 226 1.96E-35 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CDC59_RS19110 369bdb84c31c0bd540cf398bf0e20d38 237 Gene3D G3DSA:3.40.1010.10 1 119 6.1E-23 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CDC59_RS19110 369bdb84c31c0bd540cf398bf0e20d38 237 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 7 213 9.7E-28 T 29-03-2018 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 CDC59_RS19110 369bdb84c31c0bd540cf398bf0e20d38 237 Gene3D G3DSA:3.30.950.10 120 227 2.1E-14 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CDC59_RS23080 50229ad9844343eda6403fab7d23cd33 375 SUPERFAMILY SSF52738 179 367 2.48E-72 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CDC59_RS23080 50229ad9844343eda6403fab7d23cd33 375 Pfam PF00072 Response regulator receiver domain 9 111 5.6E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS23080 50229ad9844343eda6403fab7d23cd33 375 Gene3D G3DSA:3.40.50.180 179 374 7.0E-77 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CDC59_RS23080 50229ad9844343eda6403fab7d23cd33 375 PIRSF PIRSF000876 4 371 5.3E-140 T 29-03-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CDC59_RS23080 50229ad9844343eda6403fab7d23cd33 375 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 7 367 41.465 T 29-03-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CDC59_RS23080 50229ad9844343eda6403fab7d23cd33 375 SMART SM00448 7 126 9.3E-21 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS23080 50229ad9844343eda6403fab7d23cd33 375 SUPERFAMILY SSF52172 6 111 4.55E-27 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS23080 50229ad9844343eda6403fab7d23cd33 375 Gene3D G3DSA:3.40.50.2300 1 178 3.8E-28 T 29-03-2018 CDC59_RS23080 50229ad9844343eda6403fab7d23cd33 375 Pfam PF01339 CheB methylesterase 184 361 9.9E-61 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CDC59_RS10065 e0c102b3150b322d006f99775af023b3 350 Gene3D G3DSA:3.40.190.10 144 303 3.8E-31 T 29-03-2018 CDC59_RS10065 e0c102b3150b322d006f99775af023b3 350 Gene3D G3DSA:3.40.190.10 27 143 4.5E-15 T 29-03-2018 CDC59_RS10065 e0c102b3150b322d006f99775af023b3 350 SUPERFAMILY SSF53850 30 347 4.35E-67 T 29-03-2018 CDC59_RS10065 e0c102b3150b322d006f99775af023b3 350 Pfam PF13416 Bacterial extracellular solute-binding protein 50 309 1.1E-44 T 29-03-2018 CDC59_RS16790 ba6fd7897249f0dc94d923b4ccb247c7 761 Gene3D G3DSA:2.150.10.10 366 432 2.0E-5 T 29-03-2018 CDC59_RS16790 ba6fd7897249f0dc94d923b4ccb247c7 761 Gene3D G3DSA:2.150.10.10 611 729 1.1E-5 T 29-03-2018 CDC59_RS16790 ba6fd7897249f0dc94d923b4ccb247c7 761 Gene3D G3DSA:2.150.10.10 532 610 5.8E-5 T 29-03-2018 CDC59_RS16790 ba6fd7897249f0dc94d923b4ccb247c7 761 Gene3D G3DSA:2.150.10.10 434 531 2.2E-5 T 29-03-2018 CDC59_RS16790 ba6fd7897249f0dc94d923b4ccb247c7 761 SUPERFAMILY SSF51120 608 712 1.22E-9 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal CDC59_RS16790 ba6fd7897249f0dc94d923b4ccb247c7 761 SUPERFAMILY SSF51120 194 308 7.32E-6 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal CDC59_RS16790 ba6fd7897249f0dc94d923b4ccb247c7 761 SUPERFAMILY SSF51120 468 602 7.41E-15 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal CDC59_RS16790 ba6fd7897249f0dc94d923b4ccb247c7 761 SUPERFAMILY SSF51120 322 452 1.7E-8 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal CDC59_RS12190 ecdcb03a121c221a5cf7231aad203ee6 759 Gene3D G3DSA:3.40.50.220 81 150 0.027 T 29-03-2018 IPR027464 Ornithine decarboxylase, N-terminal domain KEGG: 00330+4.1.1.17|KEGG: 00480+4.1.1.17|MetaCyc: PWY-46|MetaCyc: PWY-6305 CDC59_RS12190 ecdcb03a121c221a5cf7231aad203ee6 759 SUPERFAMILY SSF53383 152 612 5.82E-113 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS12190 ecdcb03a121c221a5cf7231aad203ee6 759 Gene3D G3DSA:3.90.1150.10 460 643 6.1E-71 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS12190 ecdcb03a121c221a5cf7231aad203ee6 759 Gene3D G3DSA:3.40.640.10 152 459 1.9E-44 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDC59_RS12190 ecdcb03a121c221a5cf7231aad203ee6 759 SUPERFAMILY SSF55904 615 758 1.44E-44 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CDC59_RS12190 ecdcb03a121c221a5cf7231aad203ee6 759 PIRSF PIRSF009393 1 759 8.2E-289 T 29-03-2018 IPR011193 Ornithine/lysine/arginine decarboxylase GO:0005737|GO:0006520|GO:0016831 CDC59_RS12190 ecdcb03a121c221a5cf7231aad203ee6 759 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 152 593 4.7E-153 T 29-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 CDC59_RS12190 ecdcb03a121c221a5cf7231aad203ee6 759 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 620 745 1.3E-46 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CDC59_RS12190 ecdcb03a121c221a5cf7231aad203ee6 759 ProSitePatterns PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 393 407 - T 29-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 CDC59_RS12190 ecdcb03a121c221a5cf7231aad203ee6 759 Pfam PF03709 Orn/Lys/Arg decarboxylase, N-terminal domain 20 146 4.6E-39 T 29-03-2018 IPR005308 Orn/Lys/Arg decarboxylase, N-terminal GO:0016831 CDC59_RS12190 ecdcb03a121c221a5cf7231aad203ee6 759 Gene3D G3DSA:3.90.100.10 644 759 1.9E-35 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CDC59_RS19305 04b73fb077165b2ce3d42c6f848025eb 522 SUPERFAMILY SSF56954 16 497 4.71E-103 T 29-03-2018 CDC59_RS19305 04b73fb077165b2ce3d42c6f848025eb 522 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 23 493 3.0E-113 T 29-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 CDC59_RS19305 04b73fb077165b2ce3d42c6f848025eb 522 Pfam PF02321 Outer membrane efflux protein 76 281 2.6E-24 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CDC59_RS19305 04b73fb077165b2ce3d42c6f848025eb 522 Pfam PF02321 Outer membrane efflux protein 309 491 1.0E-26 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CDC59_RS19305 04b73fb077165b2ce3d42c6f848025eb 522 Gene3D G3DSA:1.20.1600.10 31 499 1.7E-96 T 29-03-2018 CDC59_RS04150 ec33223b9f731738844694375696b682 224 Gene3D G3DSA:3.40.50.1000 84 216 7.4E-10 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS04150 ec33223b9f731738844694375696b682 224 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 3 197 2.3E-22 T 29-03-2018 CDC59_RS04150 ec33223b9f731738844694375696b682 224 Pfam PF12710 haloacid dehalogenase-like hydrolase 4 195 8.3E-44 T 29-03-2018 CDC59_RS04150 ec33223b9f731738844694375696b682 224 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 3 207 3.6E-39 T 29-03-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like CDC59_RS04150 ec33223b9f731738844694375696b682 224 Gene3D G3DSA:1.20.1440.100 16 83 3.0E-33 T 29-03-2018 CDC59_RS04150 ec33223b9f731738844694375696b682 224 SUPERFAMILY SSF56784 2 218 7.09E-34 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS08415 c84baa28cc5bea9dd51cc0c94d0f4a16 400 SUPERFAMILY SSF55785 57 149 4.03E-6 T 29-03-2018 IPR000014 PAS domain CDC59_RS08415 c84baa28cc5bea9dd51cc0c94d0f4a16 400 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 281 399 8.7E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS08415 c84baa28cc5bea9dd51cc0c94d0f4a16 400 SMART SM00387 281 400 4.2E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS08415 c84baa28cc5bea9dd51cc0c94d0f4a16 400 Gene3D G3DSA:1.10.287.130 164 237 5.4E-14 T 29-03-2018 CDC59_RS08415 c84baa28cc5bea9dd51cc0c94d0f4a16 400 Pfam PF00512 His Kinase A (phospho-acceptor) domain 178 237 1.2E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS08415 c84baa28cc5bea9dd51cc0c94d0f4a16 400 SUPERFAMILY SSF47384 167 237 5.1E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS08415 c84baa28cc5bea9dd51cc0c94d0f4a16 400 Gene3D G3DSA:3.30.450.20 56 153 1.4E-6 T 29-03-2018 CDC59_RS08415 c84baa28cc5bea9dd51cc0c94d0f4a16 400 Gene3D G3DSA:3.30.565.10 242 400 2.1E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS08415 c84baa28cc5bea9dd51cc0c94d0f4a16 400 SUPERFAMILY SSF55874 245 398 6.55E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS08415 c84baa28cc5bea9dd51cc0c94d0f4a16 400 Pfam PF00989 PAS fold 56 147 2.4E-5 T 29-03-2018 IPR013767 PAS fold GO:0006355 CDC59_RS08415 c84baa28cc5bea9dd51cc0c94d0f4a16 400 SMART SM00388 176 241 4.3E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS08415 c84baa28cc5bea9dd51cc0c94d0f4a16 400 PRINTS PR00344 Bacterial sensor protein C-terminal signature 333 347 2.9E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS08415 c84baa28cc5bea9dd51cc0c94d0f4a16 400 PRINTS PR00344 Bacterial sensor protein C-terminal signature 362 380 2.9E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS02915 95aa19a2076f5194109d495456e7f644 189 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 1.5E-13 T 29-03-2018 CDC59_RS02915 95aa19a2076f5194109d495456e7f644 189 PRINTS PR00096 Glutamine amidotransferase superfamily signature 164 177 1.5E-13 T 29-03-2018 CDC59_RS02915 95aa19a2076f5194109d495456e7f644 189 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 1.5E-13 T 29-03-2018 CDC59_RS02915 95aa19a2076f5194109d495456e7f644 189 PRINTS PR00097 Anthranilate synthase component II signature 99 107 6.6E-35 T 29-03-2018 CDC59_RS02915 95aa19a2076f5194109d495456e7f644 189 PRINTS PR00097 Anthranilate synthase component II signature 47 56 6.6E-35 T 29-03-2018 CDC59_RS02915 95aa19a2076f5194109d495456e7f644 189 PRINTS PR00097 Anthranilate synthase component II signature 119 131 6.6E-35 T 29-03-2018 CDC59_RS02915 95aa19a2076f5194109d495456e7f644 189 PRINTS PR00097 Anthranilate synthase component II signature 164 177 6.6E-35 T 29-03-2018 CDC59_RS02915 95aa19a2076f5194109d495456e7f644 189 PRINTS PR00097 Anthranilate synthase component II signature 2 16 6.6E-35 T 29-03-2018 CDC59_RS02915 95aa19a2076f5194109d495456e7f644 189 PRINTS PR00097 Anthranilate synthase component II signature 74 85 6.6E-35 T 29-03-2018 CDC59_RS02915 95aa19a2076f5194109d495456e7f644 189 SUPERFAMILY SSF52317 1 186 4.03E-57 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CDC59_RS02915 95aa19a2076f5194109d495456e7f644 189 Pfam PF00117 Glutamine amidotransferase class-I 4 186 4.1E-56 T 29-03-2018 IPR017926 Glutamine amidotransferase CDC59_RS02915 95aa19a2076f5194109d495456e7f644 189 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 186 3.1E-83 T 29-03-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CDC59_RS02915 95aa19a2076f5194109d495456e7f644 189 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 1.4E-5 T 29-03-2018 CDC59_RS02915 95aa19a2076f5194109d495456e7f644 189 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 1.4E-5 T 29-03-2018 CDC59_RS02915 95aa19a2076f5194109d495456e7f644 189 Gene3D G3DSA:3.40.50.880 1 189 1.1E-59 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CDC59_RS08655 e4b081ed006c30ba8dbe90e77a4059c7 258 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 111 130 7.7E-7 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CDC59_RS08655 e4b081ed006c30ba8dbe90e77a4059c7 258 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 215 223 7.7E-7 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CDC59_RS08655 e4b081ed006c30ba8dbe90e77a4059c7 258 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 51 58 7.7E-7 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CDC59_RS08655 e4b081ed006c30ba8dbe90e77a4059c7 258 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 136 145 7.7E-7 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CDC59_RS08655 e4b081ed006c30ba8dbe90e77a4059c7 258 SUPERFAMILY SSF63380 6 99 1.18E-25 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CDC59_RS08655 e4b081ed006c30ba8dbe90e77a4059c7 258 Gene3D G3DSA:2.40.30.10 2 96 3.8E-17 T 29-03-2018 CDC59_RS08655 e4b081ed006c30ba8dbe90e77a4059c7 258 SUPERFAMILY SSF52343 102 256 1.2E-41 T 29-03-2018 CDC59_RS08655 e4b081ed006c30ba8dbe90e77a4059c7 258 Gene3D G3DSA:3.40.50.80 97 258 1.4E-20 T 29-03-2018 CDC59_RS08655 e4b081ed006c30ba8dbe90e77a4059c7 258 Pfam PF00970 Oxidoreductase FAD-binding domain 15 98 1.3E-9 T 29-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CDC59_RS08655 e4b081ed006c30ba8dbe90e77a4059c7 258 PRINTS PR00410 Phenol hydroxylase reductase family signature 51 58 3.9E-5 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CDC59_RS08655 e4b081ed006c30ba8dbe90e77a4059c7 258 PRINTS PR00410 Phenol hydroxylase reductase family signature 215 223 3.9E-5 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CDC59_RS08655 e4b081ed006c30ba8dbe90e77a4059c7 258 PRINTS PR00410 Phenol hydroxylase reductase family signature 111 130 3.9E-5 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CDC59_RS08655 e4b081ed006c30ba8dbe90e77a4059c7 258 Pfam PF00175 Oxidoreductase NAD-binding domain 113 230 2.2E-6 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CDC59_RS11315 1a5973fce3f4f6dce704a3a8bd42b3ac 771 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 315 447 6.0E-14 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CDC59_RS11315 1a5973fce3f4f6dce704a3a8bd42b3ac 771 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 563 685 1.8E-28 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CDC59_RS11315 1a5973fce3f4f6dce704a3a8bd42b3ac 771 SMART SM00382 559 688 3.1E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS11315 1a5973fce3f4f6dce704a3a8bd42b3ac 771 SMART SM00382 311 451 1.9E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS11315 1a5973fce3f4f6dce704a3a8bd42b3ac 771 Gene3D G3DSA:3.40.50.300 110 462 2.6E-19 T 29-03-2018 CDC59_RS11315 1a5973fce3f4f6dce704a3a8bd42b3ac 771 Gene3D G3DSA:3.40.50.300 493 699 3.2E-29 T 29-03-2018 CDC59_RS11315 1a5973fce3f4f6dce704a3a8bd42b3ac 771 SUPERFAMILY SSF52540 548 698 1.27E-31 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS11315 1a5973fce3f4f6dce704a3a8bd42b3ac 771 SUPERFAMILY SSF52540 307 479 2.73E-25 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS17595 a58a4c529cae53f6b3cfb8cead24b774 954 Gene3D G3DSA:1.10.1200.10 818 929 9.9E-17 T 29-03-2018 CDC59_RS17595 a58a4c529cae53f6b3cfb8cead24b774 954 SMART SM01294 825 891 0.0027 T 29-03-2018 CDC59_RS17595 a58a4c529cae53f6b3cfb8cead24b774 954 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1 251 1.0E-81 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CDC59_RS17595 a58a4c529cae53f6b3cfb8cead24b774 954 SMART SM00825 Beta-ketoacyl synthase 4 428 1.5E-195 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CDC59_RS17595 a58a4c529cae53f6b3cfb8cead24b774 954 Gene3D G3DSA:3.40.47.10 1 262 3.5E-83 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS17595 a58a4c529cae53f6b3cfb8cead24b774 954 Gene3D G3DSA:3.40.47.10 266 426 2.0E-60 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS17595 a58a4c529cae53f6b3cfb8cead24b774 954 SUPERFAMILY SSF53901 403 424 1.67E-92 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS17595 a58a4c529cae53f6b3cfb8cead24b774 954 SUPERFAMILY SSF53901 2 371 1.67E-92 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS17595 a58a4c529cae53f6b3cfb8cead24b774 954 Pfam PF00550 Phosphopantetheine attachment site 828 891 4.6E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS17595 a58a4c529cae53f6b3cfb8cead24b774 954 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 378 487 1.8E-16 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CDC59_RS17595 a58a4c529cae53f6b3cfb8cead24b774 954 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 259 374 1.8E-41 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CDC59_RS17595 a58a4c529cae53f6b3cfb8cead24b774 954 Gene3D G3DSA:3.40.366.10 535 684 3.0E-4 T 29-03-2018 CDC59_RS17595 a58a4c529cae53f6b3cfb8cead24b774 954 SUPERFAMILY SSF47336 818 921 1.57E-17 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS17595 a58a4c529cae53f6b3cfb8cead24b774 954 SMART SM00823 Phosphopantetheine attachment site 824 895 3.7E-13 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CDC59_RS11780 3d4b1d5c1e568f8fce83eb806f8c363b 783 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 1 75 5.9E-19 T 29-03-2018 CDC59_RS11780 3d4b1d5c1e568f8fce83eb806f8c363b 783 Pfam PF00384 Molybdopterin oxidoreductase 273 439 3.6E-14 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS11780 3d4b1d5c1e568f8fce83eb806f8c363b 783 Pfam PF00384 Molybdopterin oxidoreductase 528 627 2.0E-15 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS11780 3d4b1d5c1e568f8fce83eb806f8c363b 783 SUPERFAMILY SSF54292 1 74 2.17E-20 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CDC59_RS11780 3d4b1d5c1e568f8fce83eb806f8c363b 783 Gene3D G3DSA:3.40.50.740 273 684 8.3E-57 T 29-03-2018 CDC59_RS11780 3d4b1d5c1e568f8fce83eb806f8c363b 783 Gene3D G3DSA:2.40.40.20 691 775 3.8E-7 T 29-03-2018 CDC59_RS11780 3d4b1d5c1e568f8fce83eb806f8c363b 783 SMART SM00929 83 123 2.2E-21 T 29-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS11780 3d4b1d5c1e568f8fce83eb806f8c363b 783 ProSitePatterns PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 146 156 - T 29-03-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS11780 3d4b1d5c1e568f8fce83eb806f8c363b 783 Gene3D G3DSA:3.10.20.30 1 161 4.4E-17 T 29-03-2018 IPR012675 Beta-grasp domain CDC59_RS11780 3d4b1d5c1e568f8fce83eb806f8c363b 783 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 98 110 - T 29-03-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS11780 3d4b1d5c1e568f8fce83eb806f8c363b 783 SUPERFAMILY SSF50692 710 775 4.75E-6 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain CDC59_RS11780 3d4b1d5c1e568f8fce83eb806f8c363b 783 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 31 48 - T 29-03-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS11780 3d4b1d5c1e568f8fce83eb806f8c363b 783 SUPERFAMILY SSF53706 214 651 3.26E-90 T 29-03-2018 CDC59_RS11780 3d4b1d5c1e568f8fce83eb806f8c363b 783 TIGRFAM TIGR01973 NuoG: NADH dehydrogenase (quinone), G subunit 4 627 5.1E-219 T 29-03-2018 IPR010228 NADH:ubiquinone oxidoreductase, subunit G GO:0016651|GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS11780 3d4b1d5c1e568f8fce83eb806f8c363b 783 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 83 122 3.9E-17 T 29-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS11780 3d4b1d5c1e568f8fce83eb806f8c363b 783 SUPERFAMILY SSF54862 75 211 1.34E-36 T 29-03-2018 CDC59_RS12625 f5a8953a1196e3f6a4f20cede1c9a5d5 221 Pfam PF00072 Response regulator receiver domain 9 120 1.7E-16 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS12625 f5a8953a1196e3f6a4f20cede1c9a5d5 221 SMART SM00448 6 120 1.2E-17 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS12625 f5a8953a1196e3f6a4f20cede1c9a5d5 221 Gene3D G3DSA:1.10.10.10 150 221 1.2E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS12625 f5a8953a1196e3f6a4f20cede1c9a5d5 221 Gene3D G3DSA:3.40.50.2300 3 129 1.1E-21 T 29-03-2018 CDC59_RS12625 f5a8953a1196e3f6a4f20cede1c9a5d5 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 5.0E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS12625 f5a8953a1196e3f6a4f20cede1c9a5d5 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 5.0E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS12625 f5a8953a1196e3f6a4f20cede1c9a5d5 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 5.0E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS12625 f5a8953a1196e3f6a4f20cede1c9a5d5 221 SUPERFAMILY SSF46894 150 217 2.18E-17 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CDC59_RS12625 f5a8953a1196e3f6a4f20cede1c9a5d5 221 SMART SM00421 155 212 4.8E-20 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS12625 f5a8953a1196e3f6a4f20cede1c9a5d5 221 Pfam PF00196 Bacterial regulatory proteins, luxR family 158 210 3.5E-16 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS12625 f5a8953a1196e3f6a4f20cede1c9a5d5 221 ProSitePatterns PS00622 LuxR-type HTH domain signature. 172 199 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS12625 f5a8953a1196e3f6a4f20cede1c9a5d5 221 SUPERFAMILY SSF52172 7 125 2.56E-21 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS03600 a228f37bc6d7dd295caf97178a845ce7 473 SMART SM00981 67 165 1.4E-18 T 29-03-2018 IPR004114 THUMP domain GO:0003723 CDC59_RS03600 a228f37bc6d7dd295caf97178a845ce7 473 Gene3D G3DSA:3.40.50.150 104 404 1.7E-26 T 29-03-2018 CDC59_RS03600 a228f37bc6d7dd295caf97178a845ce7 473 Pfam PF02926 THUMP domain 44 165 8.9E-10 T 29-03-2018 IPR004114 THUMP domain GO:0003723 CDC59_RS03600 a228f37bc6d7dd295caf97178a845ce7 473 SUPERFAMILY SSF53335 270 330 3.9E-32 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS03600 a228f37bc6d7dd295caf97178a845ce7 473 SUPERFAMILY SSF53335 390 444 3.9E-32 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS03600 a228f37bc6d7dd295caf97178a845ce7 473 SUPERFAMILY SSF53335 158 230 3.9E-32 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS03600 a228f37bc6d7dd295caf97178a845ce7 473 Pfam PF01170 Putative RNA methylase family UPF0020 173 329 3.5E-31 T 29-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CDC59_RS03650 ba9eb534bbf67021d906f5de3689b652 689 SUPERFAMILY SSF56935 9 689 2.11E-133 T 29-03-2018 CDC59_RS03650 ba9eb534bbf67021d906f5de3689b652 689 Pfam PF07715 TonB-dependent Receptor Plug Domain 48 151 7.6E-19 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CDC59_RS03650 ba9eb534bbf67021d906f5de3689b652 689 Gene3D G3DSA:2.170.130.10 11 163 1.8E-26 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CDC59_RS03650 ba9eb534bbf67021d906f5de3689b652 689 Gene3D G3DSA:2.40.170.20 164 689 1.4E-87 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CDC59_RS03650 ba9eb534bbf67021d906f5de3689b652 689 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 50 689 2.5E-116 T 29-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 CDC59_RS03650 ba9eb534bbf67021d906f5de3689b652 689 Pfam PF00593 TonB dependent receptor 225 688 4.7E-65 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CDC59_RS13735 b44ee7b9d5ea53a43940b784a405eae6 193 SUPERFAMILY SSF50249 1 63 8.57E-19 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDC59_RS13735 b44ee7b9d5ea53a43940b784a405eae6 193 Gene3D G3DSA:1.10.8.10 138 193 1.1E-10 T 29-03-2018 CDC59_RS13735 b44ee7b9d5ea53a43940b784a405eae6 193 SUPERFAMILY SSF47781 66 132 2.22E-20 T 29-03-2018 IPR010994 RuvA domain 2-like CDC59_RS13735 b44ee7b9d5ea53a43940b784a405eae6 193 SMART SM00278 108 127 0.0016 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CDC59_RS13735 b44ee7b9d5ea53a43940b784a405eae6 193 SMART SM00278 73 92 10.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CDC59_RS13735 b44ee7b9d5ea53a43940b784a405eae6 193 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 191 31.168 T 29-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 CDC59_RS13735 b44ee7b9d5ea53a43940b784a405eae6 193 Pfam PF07499 RuvA, C-terminal domain 151 191 3.5E-12 T 29-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 CDC59_RS13735 b44ee7b9d5ea53a43940b784a405eae6 193 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 189 1.3E-52 T 29-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 CDC59_RS13735 b44ee7b9d5ea53a43940b784a405eae6 193 Gene3D G3DSA:1.10.150.280 57 80 0.033 T 29-03-2018 CDC59_RS13735 b44ee7b9d5ea53a43940b784a405eae6 193 Pfam PF01330 RuvA N terminal domain 1 62 3.8E-21 T 29-03-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 CDC59_RS13735 b44ee7b9d5ea53a43940b784a405eae6 193 SUPERFAMILY SSF46929 151 192 9.94E-9 T 29-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 CDC59_RS13735 b44ee7b9d5ea53a43940b784a405eae6 193 Gene3D G3DSA:1.10.150.20 81 134 7.3E-16 T 29-03-2018 CDC59_RS13735 b44ee7b9d5ea53a43940b784a405eae6 193 Gene3D G3DSA:2.40.50.140 1 56 5.0E-24 T 29-03-2018 CDC59_RS13735 b44ee7b9d5ea53a43940b784a405eae6 193 Pfam PF14520 Helix-hairpin-helix domain 72 129 8.6E-18 T 29-03-2018 CDC59_RS08565 f56bc854d35f975bf97872bffc8f6c3e 968 Pfam PF08364 Bacterial translation initiation factor IF-2 associated region 62 100 1.1E-12 T 29-03-2018 IPR013575 Initiation factor 2 associated domain, bacterial CDC59_RS08565 f56bc854d35f975bf97872bffc8f6c3e 968 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 470 627 5.8E-34 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CDC59_RS08565 f56bc854d35f975bf97872bffc8f6c3e 968 SUPERFAMILY SSF52540 464 637 1.0E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS08565 f56bc854d35f975bf97872bffc8f6c3e 968 SUPERFAMILY SSF52156 746 875 4.05E-38 T 29-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 CDC59_RS08565 f56bc854d35f975bf97872bffc8f6c3e 968 Pfam PF11987 Translation-initiation factor 2 754 858 4.0E-38 T 29-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 CDC59_RS08565 f56bc854d35f975bf97872bffc8f6c3e 968 ProSitePatterns PS01176 Initiation factor 2 signature. 919 941 - T 29-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CDC59_RS08565 f56bc854d35f975bf97872bffc8f6c3e 968 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 385 968 1.4E-264 T 29-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CDC59_RS08565 f56bc854d35f975bf97872bffc8f6c3e 968 Pfam PF00009 Elongation factor Tu GTP binding domain 473 628 7.0E-36 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDC59_RS08565 f56bc854d35f975bf97872bffc8f6c3e 968 Gene3D G3DSA:3.40.50.300 463 638 6.9E-41 T 29-03-2018 CDC59_RS08565 f56bc854d35f975bf97872bffc8f6c3e 968 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 966 17.581 T 29-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CDC59_RS08565 f56bc854d35f975bf97872bffc8f6c3e 968 Gene3D G3DSA:3.40.50.10050 784 846 1.7E-26 T 29-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 CDC59_RS08565 f56bc854d35f975bf97872bffc8f6c3e 968 Gene3D G3DSA:2.40.30.10 869 967 4.8E-30 T 29-03-2018 CDC59_RS08565 f56bc854d35f975bf97872bffc8f6c3e 968 SUPERFAMILY SSF50447 642 723 9.24E-25 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CDC59_RS08565 f56bc854d35f975bf97872bffc8f6c3e 968 SUPERFAMILY SSF50447 870 966 4.32E-34 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CDC59_RS08565 f56bc854d35f975bf97872bffc8f6c3e 968 Gene3D G3DSA:3.30.56.50 393 434 6.8E-11 T 29-03-2018 CDC59_RS08565 f56bc854d35f975bf97872bffc8f6c3e 968 Gene3D G3DSA:3.30.56.50 4 46 3.3E-8 T 29-03-2018 CDC59_RS08565 f56bc854d35f975bf97872bffc8f6c3e 968 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 390 440 6.9E-15 T 29-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal CDC59_RS08565 f56bc854d35f975bf97872bffc8f6c3e 968 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 1 51 1.7E-7 T 29-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal CDC59_RS08565 f56bc854d35f975bf97872bffc8f6c3e 968 Gene3D G3DSA:2.40.30.10 641 783 2.0E-30 T 29-03-2018 CDC59_RS08565 f56bc854d35f975bf97872bffc8f6c3e 968 SUPERFAMILY SSF46955 3 51 3.11E-10 T 29-03-2018 IPR009061 Putative DNA-binding domain CDC59_RS07240 3d7e9b9f47da792f4f34466423ae3f49 204 TIGRFAM TIGR02665 molyb_mobA: molybdenum cofactor guanylyltransferase 7 197 4.2E-65 T 29-03-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 CDC59_RS07240 3d7e9b9f47da792f4f34466423ae3f49 204 Pfam PF12804 MobA-like NTP transferase domain 9 170 8.4E-33 T 29-03-2018 IPR025877 MobA-like NTP transferase CDC59_RS07240 3d7e9b9f47da792f4f34466423ae3f49 204 SUPERFAMILY SSF53448 6 197 1.34E-30 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDC59_RS07240 3d7e9b9f47da792f4f34466423ae3f49 204 Gene3D G3DSA:3.90.550.10 2 203 1.7E-32 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDC59_RS07240 3d7e9b9f47da792f4f34466423ae3f49 204 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 5 200 27.595 T 29-03-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 CDC59_RS04175 5bea1164b56d47dd1c3b0ff649d99901 107 Pfam PF02805 Metal binding domain of Ada 25 75 2.8E-5 T 29-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 CDC59_RS04175 5bea1164b56d47dd1c3b0ff649d99901 107 SUPERFAMILY SSF57884 23 83 1.44E-13 T 29-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 CDC59_RS04175 5bea1164b56d47dd1c3b0ff649d99901 107 Gene3D G3DSA:3.40.10.10 2 78 2.0E-20 T 29-03-2018 IPR035451 Ada-like domain CDC59_RS07410 8afd655ddaaea4a755b68b22111668de 668 Gene3D G3DSA:1.10.150.20 613 668 3.5E-14 T 29-03-2018 CDC59_RS07410 8afd655ddaaea4a755b68b22111668de 668 Gene3D G3DSA:4.10.860.10 212 273 6.7E-13 T 29-03-2018 IPR001943 UVR domain GO:0005515 CDC59_RS07410 8afd655ddaaea4a755b68b22111668de 668 Pfam PF01541 GIY-YIG catalytic domain 49 123 1.6E-8 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CDC59_RS07410 8afd655ddaaea4a755b68b22111668de 668 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 39 315 1.6E-93 T 29-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 CDC59_RS07410 8afd655ddaaea4a755b68b22111668de 668 Pfam PF02151 UvrB/uvrC motif 234 266 7.9E-7 T 29-03-2018 IPR001943 UVR domain GO:0005515 CDC59_RS07410 8afd655ddaaea4a755b68b22111668de 668 SUPERFAMILY SSF47781 574 668 4.45E-20 T 29-03-2018 IPR010994 RuvA domain 2-like CDC59_RS07410 8afd655ddaaea4a755b68b22111668de 668 Hamap MF_00203 UvrABC system protein C [uvrC]. 34 666 26.419 T 29-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 CDC59_RS07410 8afd655ddaaea4a755b68b22111668de 668 SUPERFAMILY SSF46600 220 272 6.8E-12 T 29-03-2018 IPR001943 UVR domain GO:0005515 CDC59_RS07410 8afd655ddaaea4a755b68b22111668de 668 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 450 601 5.8E-43 T 29-03-2018 IPR001162 UvrC family homology region CDC59_RS07410 8afd655ddaaea4a755b68b22111668de 668 SMART SM00278 615 634 1.3 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CDC59_RS07410 8afd655ddaaea4a755b68b22111668de 668 SMART SM00278 647 666 97.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CDC59_RS07410 8afd655ddaaea4a755b68b22111668de 668 SMART SM00465 47 128 1.1E-18 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CDC59_RS07410 8afd655ddaaea4a755b68b22111668de 668 Pfam PF14520 Helix-hairpin-helix domain 617 667 1.3E-6 T 29-03-2018 CDC59_RS07410 8afd655ddaaea4a755b68b22111668de 668 SUPERFAMILY SSF82771 46 130 3.92E-22 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CDC59_RS07410 8afd655ddaaea4a755b68b22111668de 668 Gene3D G3DSA:3.40.1440.10 34 131 3.0E-21 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CDC59_RS09560 3b03562b2b21dcd4ccd3929dec22ea80 96 PIRSF PIRSF001486 1 94 2.0E-45 T 29-03-2018 IPR003464 Muconolactone delta-isomerase GO:0006725 KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185 CDC59_RS09560 3b03562b2b21dcd4ccd3929dec22ea80 96 SUPERFAMILY SSF54909 1 95 1.93E-39 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CDC59_RS09560 3b03562b2b21dcd4ccd3929dec22ea80 96 ProDom PD006619 ISOMERASE MUCONOLACTONE DELTA-ISOMERASE HYDROCARBONS MIASE AROMATIC CATABOLISM METHYLMUCONOLACTONE DIRECT SEQUENCING 1 57 1.0E-13 T 29-03-2018 IPR003464 Muconolactone delta-isomerase GO:0006725 KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185 CDC59_RS09560 3b03562b2b21dcd4ccd3929dec22ea80 96 TIGRFAM TIGR03221 muco_delta: muconolactone delta-isomerase 2 91 1.2E-45 T 29-03-2018 IPR003464 Muconolactone delta-isomerase GO:0006725 KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185 CDC59_RS09560 3b03562b2b21dcd4ccd3929dec22ea80 96 Pfam PF02426 Muconolactone delta-isomerase 1 90 8.4E-42 T 29-03-2018 IPR026029 Muconolactone isomerase domain KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185 CDC59_RS11490 df38a4944abb8b22f6473ddb1d35f9a5 329 Gene3D G3DSA:3.40.50.720 7 158 2.8E-27 T 29-03-2018 CDC59_RS11490 df38a4944abb8b22f6473ddb1d35f9a5 329 Gene3D G3DSA:3.90.110.10 159 326 8.1E-45 T 29-03-2018 CDC59_RS11490 df38a4944abb8b22f6473ddb1d35f9a5 329 Hamap MF_01517 Malate dehydrogenase [mdh]. 2 328 54.901 T 29-03-2018 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 CDC59_RS11490 df38a4944abb8b22f6473ddb1d35f9a5 329 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 160 321 2.2E-29 T 29-03-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 CDC59_RS11490 df38a4944abb8b22f6473ddb1d35f9a5 329 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 6 155 5.0E-37 T 29-03-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 CDC59_RS11490 df38a4944abb8b22f6473ddb1d35f9a5 329 PIRSF PIRSF000102 2 327 1.9E-64 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CDC59_RS11490 df38a4944abb8b22f6473ddb1d35f9a5 329 TIGRFAM TIGR01759 MalateDH-SF1: malate dehydrogenase 4 322 2.5E-142 T 29-03-2018 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 CDC59_RS11490 df38a4944abb8b22f6473ddb1d35f9a5 329 SUPERFAMILY SSF56327 160 328 1.36E-54 T 29-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CDC59_RS11490 df38a4944abb8b22f6473ddb1d35f9a5 329 SUPERFAMILY SSF51735 4 158 1.59E-47 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS13035 4cb10c83598a639734ad3ebd7e2f64dc 148 Pfam PF04138 GtrA-like protein 35 147 1.6E-19 T 29-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 CDC59_RS02880 3002a935bcdb30eab783cb63d8e727b8 638 Gene3D G3DSA:2.30.42.10 518 625 1.6E-14 T 29-03-2018 CDC59_RS02880 3002a935bcdb30eab783cb63d8e727b8 638 Pfam PF05299 M61 glycyl aminopeptidase 306 422 1.5E-46 T 29-03-2018 IPR007963 Peptidase M61, catalytic domain CDC59_RS02880 3002a935bcdb30eab783cb63d8e727b8 638 Gene3D G3DSA:1.10.390.10 295 491 4.1E-25 T 29-03-2018 CDC59_RS02880 3002a935bcdb30eab783cb63d8e727b8 638 Pfam PF13180 PDZ domain 519 596 1.2E-12 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CDC59_RS02880 3002a935bcdb30eab783cb63d8e727b8 638 PIRSF PIRSF016493 9 624 1.1E-204 T 29-03-2018 IPR024191 Peptidase M61 CDC59_RS02880 3002a935bcdb30eab783cb63d8e727b8 638 SUPERFAMILY SSF55486 269 454 2.2E-8 T 29-03-2018 CDC59_RS02880 3002a935bcdb30eab783cb63d8e727b8 638 SMART SM00228 518 587 2.5E-7 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CDC59_RS02880 3002a935bcdb30eab783cb63d8e727b8 638 SUPERFAMILY SSF50156 516 607 3.29E-13 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CDC59_RS07920 b50ad6656eae50fc5da7009979a31899 625 PIRSF PIRSF002741 9 618 3.3E-90 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CDC59_RS07920 b50ad6656eae50fc5da7009979a31899 625 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 109 529 1.0E-82 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CDC59_RS07920 b50ad6656eae50fc5da7009979a31899 625 Gene3D G3DSA:3.10.105.10 344 586 1.4E-53 T 29-03-2018 CDC59_RS07920 b50ad6656eae50fc5da7009979a31899 625 SUPERFAMILY SSF53850 58 378 2.17E-117 T 29-03-2018 CDC59_RS07920 b50ad6656eae50fc5da7009979a31899 625 SUPERFAMILY SSF53850 408 619 2.17E-117 T 29-03-2018 CDC59_RS07920 b50ad6656eae50fc5da7009979a31899 625 Gene3D G3DSA:3.40.190.10 183 343 2.8E-29 T 29-03-2018 CDC59_RS07920 b50ad6656eae50fc5da7009979a31899 625 Gene3D G3DSA:3.90.76.10 80 182 1.5E-19 T 29-03-2018 CDC59_RS15445 04d1097e340f5a658ea259a87b26ccc7 337 Hamap MF_01110 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 1 307 52.462 T 29-03-2018 IPR010136 N-acetyl-gamma-glutamyl-phosphate reductase, type 2 GO:0003942|GO:0005737|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CDC59_RS15445 04d1097e340f5a658ea259a87b26ccc7 337 Gene3D G3DSA:3.30.360.10 126 288 1.8E-42 T 29-03-2018 CDC59_RS15445 04d1097e340f5a658ea259a87b26ccc7 337 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 43 99 4.7E-9 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CDC59_RS15445 04d1097e340f5a658ea259a87b26ccc7 337 Gene3D G3DSA:3.40.50.720 1 125 3.5E-15 T 29-03-2018 CDC59_RS15445 04d1097e340f5a658ea259a87b26ccc7 337 SMART SM00859 4 105 4.9E-17 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CDC59_RS15445 04d1097e340f5a658ea259a87b26ccc7 337 TIGRFAM TIGR01851 argC_other: N-acetyl-gamma-glutamyl-phosphate reductase 2 307 4.3E-161 T 29-03-2018 IPR010136 N-acetyl-gamma-glutamyl-phosphate reductase, type 2 GO:0003942|GO:0005737|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CDC59_RS15445 04d1097e340f5a658ea259a87b26ccc7 337 SUPERFAMILY SSF55347 116 288 3.43E-36 T 29-03-2018 CDC59_RS15445 04d1097e340f5a658ea259a87b26ccc7 337 SUPERFAMILY SSF51735 1 137 7.88E-34 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS05985 b35bf70b0a24b1a888223f94002f3a7e 131 Pfam PF02627 Carboxymuconolactone decarboxylase family 37 118 1.1E-25 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CDC59_RS05985 b35bf70b0a24b1a888223f94002f3a7e 131 Gene3D G3DSA:1.20.1290.10 8 131 1.3E-35 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CDC59_RS05985 b35bf70b0a24b1a888223f94002f3a7e 131 SUPERFAMILY SSF69118 4 126 4.32E-38 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CDC59_RS05985 b35bf70b0a24b1a888223f94002f3a7e 131 TIGRFAM TIGR02425 decarb_PcaC: 4-carboxymuconolactone decarboxylase 3 124 1.1E-59 T 29-03-2018 IPR012788 4-carboxymuconolactone decarboxylase KEGG: 00362+4.1.1.44 CDC59_RS02220 48408666346bb9272583c56a08a953b1 701 Gene3D G3DSA:3.30.230.10 499 614 2.6E-45 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CDC59_RS02220 48408666346bb9272583c56a08a953b1 701 SMART SM00889 485 604 2.1E-74 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CDC59_RS02220 48408666346bb9272583c56a08a953b1 701 SUPERFAMILY SSF54980 409 486 4.68E-26 T 29-03-2018 IPR035647 EF-G domain III/V-like CDC59_RS02220 48408666346bb9272583c56a08a953b1 701 PRINTS PR00315 GTP-binding elongation factor signature 101 112 4.3E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDC59_RS02220 48408666346bb9272583c56a08a953b1 701 PRINTS PR00315 GTP-binding elongation factor signature 137 146 4.3E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDC59_RS02220 48408666346bb9272583c56a08a953b1 701 PRINTS PR00315 GTP-binding elongation factor signature 85 95 4.3E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDC59_RS02220 48408666346bb9272583c56a08a953b1 701 PRINTS PR00315 GTP-binding elongation factor signature 12 25 4.3E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDC59_RS02220 48408666346bb9272583c56a08a953b1 701 PRINTS PR00315 GTP-binding elongation factor signature 58 66 4.3E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDC59_RS02220 48408666346bb9272583c56a08a953b1 701 SUPERFAMILY SSF54211 484 605 1.69E-44 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CDC59_RS02220 48408666346bb9272583c56a08a953b1 701 TIGRFAM TIGR00484 EF-G: translation elongation factor G 2 698 0.0 T 29-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CDC59_RS02220 48408666346bb9272583c56a08a953b1 701 Pfam PF00009 Elongation factor Tu GTP binding domain 9 288 1.3E-63 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDC59_RS02220 48408666346bb9272583c56a08a953b1 701 SUPERFAMILY SSF54980 609 695 1.06E-29 T 29-03-2018 IPR035647 EF-G domain III/V-like CDC59_RS02220 48408666346bb9272583c56a08a953b1 701 Pfam PF00679 Elongation factor G C-terminus 606 692 1.5E-32 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like CDC59_RS02220 48408666346bb9272583c56a08a953b1 701 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 187 1.4E-31 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CDC59_RS02220 48408666346bb9272583c56a08a953b1 701 Gene3D G3DSA:3.30.70.870 405 498 1.4E-38 T 29-03-2018 CDC59_RS02220 48408666346bb9272583c56a08a953b1 701 SUPERFAMILY SSF52540 6 288 9.27E-106 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS02220 48408666346bb9272583c56a08a953b1 701 Pfam PF14492 Elongation Factor G, domain II 409 483 1.2E-35 T 29-03-2018 CDC59_RS02220 48408666346bb9272583c56a08a953b1 701 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site CDC59_RS02220 48408666346bb9272583c56a08a953b1 701 Pfam PF03764 Elongation factor G, domain IV 484 604 1.8E-47 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CDC59_RS02220 48408666346bb9272583c56a08a953b1 701 SMART SM00838 606 694 1.1E-58 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like CDC59_RS02220 48408666346bb9272583c56a08a953b1 701 Gene3D G3DSA:3.30.70.240 615 693 1.2E-32 T 29-03-2018 CDC59_RS02220 48408666346bb9272583c56a08a953b1 701 Gene3D G3DSA:3.40.50.300 1 293 2.0E-57 T 29-03-2018 CDC59_RS02220 48408666346bb9272583c56a08a953b1 701 SUPERFAMILY SSF50447 271 407 3.06E-34 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CDC59_RS02220 48408666346bb9272583c56a08a953b1 701 Gene3D G3DSA:2.40.30.10 295 404 2.3E-29 T 29-03-2018 CDC59_RS02220 48408666346bb9272583c56a08a953b1 701 Pfam PF03144 Elongation factor Tu domain 2 329 396 7.8E-17 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CDC59_RS02220 48408666346bb9272583c56a08a953b1 701 Hamap MF_00054_B Elongation factor G [fusA]. 6 698 111.037 T 29-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CDC59_RS02180 0d5add7934c45a6292cb4b64a1540217 1593 Pfam PF07703 Alpha-2-macroglobulin family N-terminal region 669 815 9.4E-15 T 29-03-2018 IPR011625 Alpha-2-macroglobulin, N-terminal 2 CDC59_RS02180 0d5add7934c45a6292cb4b64a1540217 1593 Gene3D G3DSA:1.50.10.20 1070 1370 1.8E-14 T 29-03-2018 CDC59_RS02180 0d5add7934c45a6292cb4b64a1540217 1593 Gene3D G3DSA:2.60.40.10 344 437 1.2E-8 T 29-03-2018 IPR013783 Immunoglobulin-like fold CDC59_RS02180 0d5add7934c45a6292cb4b64a1540217 1593 SMART SM01360 882 976 2.0E-18 T 29-03-2018 IPR001599 Alpha-2-macroglobulin GO:0004866 CDC59_RS02180 0d5add7934c45a6292cb4b64a1540217 1593 Gene3D G3DSA:2.60.40.10 552 656 0.02 T 29-03-2018 IPR013783 Immunoglobulin-like fold CDC59_RS02180 0d5add7934c45a6292cb4b64a1540217 1593 Gene3D G3DSA:2.60.40.10 766 928 1.7E-9 T 29-03-2018 IPR013783 Immunoglobulin-like fold CDC59_RS02180 0d5add7934c45a6292cb4b64a1540217 1593 Gene3D G3DSA:2.60.40.10 245 321 2.0E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold CDC59_RS02180 0d5add7934c45a6292cb4b64a1540217 1593 Gene3D G3DSA:2.60.40.10 440 551 8.5E-7 T 29-03-2018 IPR013783 Immunoglobulin-like fold CDC59_RS02180 0d5add7934c45a6292cb4b64a1540217 1593 Pfam PF00207 Alpha-2-macroglobulin family 882 974 1.5E-20 T 29-03-2018 IPR001599 Alpha-2-macroglobulin GO:0004866 CDC59_RS02180 0d5add7934c45a6292cb4b64a1540217 1593 SUPERFAMILY SSF48239 1082 1178 1.36E-14 T 29-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CDC59_RS02180 0d5add7934c45a6292cb4b64a1540217 1593 SMART SM01359 669 815 8.0E-31 T 29-03-2018 IPR011625 Alpha-2-macroglobulin, N-terminal 2 CDC59_RS02180 0d5add7934c45a6292cb4b64a1540217 1593 Pfam PF01835 MG2 domain 344 440 6.5E-16 T 29-03-2018 IPR002890 Alpha-2-macroglobulin, N-terminal GO:0004866 CDC59_RS02180 0d5add7934c45a6292cb4b64a1540217 1593 Pfam PF10569 Alpha-macro-globulin thiol-ester bond-forming region 1082 1107 1.1E-5 T 29-03-2018 IPR019565 Alpha-2-macroglobulin, thiol-ester bond-forming CDC59_RS04940 cc9aa2ddf961e33a5ce366daa317512c 744 SUPERFAMILY SSF48113 34 437 6.48E-160 T 29-03-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 CDC59_RS04940 cc9aa2ddf961e33a5ce366daa317512c 744 Gene3D G3DSA:1.10.520.10 448 607 1.2E-35 T 29-03-2018 CDC59_RS04940 cc9aa2ddf961e33a5ce366daa317512c 744 SUPERFAMILY SSF48113 438 741 1.62E-118 T 29-03-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 CDC59_RS04940 cc9aa2ddf961e33a5ce366daa317512c 744 ProSitePatterns PS00436 Peroxidases active site signature. 103 114 - T 29-03-2018 IPR019794 Peroxidase, active site GO:0004601|GO:0055114 CDC59_RS04940 cc9aa2ddf961e33a5ce366daa317512c 744 Gene3D G3DSA:1.10.420.10 241 405 4.4E-41 T 29-03-2018 CDC59_RS04940 cc9aa2ddf961e33a5ce366daa317512c 744 Gene3D G3DSA:1.10.420.10 608 719 5.3E-38 T 29-03-2018 CDC59_RS04940 cc9aa2ddf961e33a5ce366daa317512c 744 Hamap MF_01961 Catalase-peroxidase [katG]. 22 744 43.0 T 29-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 CDC59_RS04940 cc9aa2ddf961e33a5ce366daa317512c 744 Gene3D G3DSA:1.10.520.10 69 227 1.3E-38 T 29-03-2018 CDC59_RS04940 cc9aa2ddf961e33a5ce366daa317512c 744 PRINTS PR00458 Haem peroxidase superfamily signature 163 180 2.9E-21 T 29-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 CDC59_RS04940 cc9aa2ddf961e33a5ce366daa317512c 744 PRINTS PR00458 Haem peroxidase superfamily signature 267 282 2.9E-21 T 29-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 CDC59_RS04940 cc9aa2ddf961e33a5ce366daa317512c 744 PRINTS PR00458 Haem peroxidase superfamily signature 181 193 2.9E-21 T 29-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 CDC59_RS04940 cc9aa2ddf961e33a5ce366daa317512c 744 PRINTS PR00458 Haem peroxidase superfamily signature 326 341 2.9E-21 T 29-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 CDC59_RS04940 cc9aa2ddf961e33a5ce366daa317512c 744 PRINTS PR00458 Haem peroxidase superfamily signature 103 117 2.9E-21 T 29-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 CDC59_RS04940 cc9aa2ddf961e33a5ce366daa317512c 744 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 80 105 1.1E-57 T 29-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 CDC59_RS04940 cc9aa2ddf961e33a5ce366daa317512c 744 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 65 78 1.1E-57 T 29-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 CDC59_RS04940 cc9aa2ddf961e33a5ce366daa317512c 744 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 488 514 1.1E-57 T 29-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 CDC59_RS04940 cc9aa2ddf961e33a5ce366daa317512c 744 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 39 61 1.1E-57 T 29-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 CDC59_RS04940 cc9aa2ddf961e33a5ce366daa317512c 744 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 275 298 1.1E-57 T 29-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 CDC59_RS04940 cc9aa2ddf961e33a5ce366daa317512c 744 Pfam PF00141 Peroxidase 94 402 1.1E-49 T 29-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 CDC59_RS04940 cc9aa2ddf961e33a5ce366daa317512c 744 Pfam PF00141 Peroxidase 410 716 1.3E-40 T 29-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 CDC59_RS04940 cc9aa2ddf961e33a5ce366daa317512c 744 ProSitePatterns PS00435 Peroxidases proximal heme-ligand signature. 267 277 - T 29-03-2018 IPR019793 Peroxidases heam-ligand binding site Reactome: R-HSA-2408557 CDC59_RS04940 cc9aa2ddf961e33a5ce366daa317512c 744 TIGRFAM TIGR00198 cat_per_HPI: catalase/peroxidase HPI 26 742 0.0 T 29-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 CDC59_RS01070 7df8c4b970a7d0993ef10f9179c97bd6 591 SUPERFAMILY SSF52518 369 570 1.48E-51 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CDC59_RS01070 7df8c4b970a7d0993ef10f9179c97bd6 591 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 194 328 6.5E-33 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CDC59_RS01070 7df8c4b970a7d0993ef10f9179c97bd6 591 Gene3D G3DSA:3.40.50.970 1 192 5.3E-51 T 29-03-2018 CDC59_RS01070 7df8c4b970a7d0993ef10f9179c97bd6 591 SUPERFAMILY SSF52467 186 376 5.78E-45 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CDC59_RS01070 7df8c4b970a7d0993ef10f9179c97bd6 591 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 393 553 9.9E-37 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CDC59_RS01070 7df8c4b970a7d0993ef10f9179c97bd6 591 TIGRFAM TIGR01504 glyox_carbo_lig: glyoxylate carboligase 3 579 0.0 T 29-03-2018 IPR006397 Glyoxylate carboligase GO:0009028|GO:0009436 KEGG: 00630+4.1.1.47 CDC59_RS01070 7df8c4b970a7d0993ef10f9179c97bd6 591 SUPERFAMILY SSF52518 1 185 8.14E-50 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CDC59_RS01070 7df8c4b970a7d0993ef10f9179c97bd6 591 Gene3D G3DSA:3.40.50.1220 193 358 1.0E-41 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CDC59_RS01070 7df8c4b970a7d0993ef10f9179c97bd6 591 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 172 1.6E-52 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CDC59_RS01070 7df8c4b970a7d0993ef10f9179c97bd6 591 Gene3D G3DSA:3.40.50.970 359 581 7.1E-40 T 29-03-2018 CDC59_RS13415 482bffa5a485079519753b70ffd7adb8 168 Pfam PF00114 Pilin (bacterial filament) 44 168 5.4E-15 T 29-03-2018 IPR001082 Fimbrial protein pilin GO:0007155|GO:0009289 CDC59_RS13415 482bffa5a485079519753b70ffd7adb8 168 Pfam PF07963 Prokaryotic N-terminal methylation motif 9 34 2.2E-10 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS13415 482bffa5a485079519753b70ffd7adb8 168 SUPERFAMILY SSF54523 15 167 1.46E-21 T 29-03-2018 CDC59_RS13415 482bffa5a485079519753b70ffd7adb8 168 Gene3D G3DSA:3.30.700.10 15 168 5.9E-29 T 29-03-2018 CDC59_RS13415 482bffa5a485079519753b70ffd7adb8 168 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 12 35 1.5E-10 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS13415 482bffa5a485079519753b70ffd7adb8 168 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 13 33 - T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS00110 29c1aa41b7ed3cc40cc9ab23c16b051b 275 Pfam PF00072 Response regulator receiver domain 5 117 7.0E-14 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS00110 29c1aa41b7ed3cc40cc9ab23c16b051b 275 Gene3D G3DSA:1.10.10.10 127 234 2.8E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS00110 29c1aa41b7ed3cc40cc9ab23c16b051b 275 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 229 1.1E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDC59_RS00110 29c1aa41b7ed3cc40cc9ab23c16b051b 275 SUPERFAMILY SSF46894 123 230 1.73E-25 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CDC59_RS00110 29c1aa41b7ed3cc40cc9ab23c16b051b 275 Gene3D G3DSA:3.40.50.2300 1 126 2.4E-24 T 29-03-2018 CDC59_RS00110 29c1aa41b7ed3cc40cc9ab23c16b051b 275 SUPERFAMILY SSF52172 3 129 5.27E-28 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS00110 29c1aa41b7ed3cc40cc9ab23c16b051b 275 SMART SM00862 154 229 9.1E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDC59_RS00110 29c1aa41b7ed3cc40cc9ab23c16b051b 275 SMART SM00448 3 116 6.9E-20 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS08765 38985c81b09fec3c3a50b2b08134ece8 439 Pfam PF01842 ACT domain 357 424 9.1E-15 T 29-03-2018 IPR002912 ACT domain CDC59_RS08765 38985c81b09fec3c3a50b2b08134ece8 439 SUPERFAMILY SSF51735 1 161 5.52E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS08765 38985c81b09fec3c3a50b2b08134ece8 439 Gene3D G3DSA:3.30.360.10 161 301 1.8E-51 T 29-03-2018 CDC59_RS08765 38985c81b09fec3c3a50b2b08134ece8 439 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 132 1.8E-23 T 29-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 CDC59_RS08765 38985c81b09fec3c3a50b2b08134ece8 439 SUPERFAMILY SSF55021 355 426 4.58E-12 T 29-03-2018 CDC59_RS08765 38985c81b09fec3c3a50b2b08134ece8 439 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 186 208 - T 29-03-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CDC59_RS08765 38985c81b09fec3c3a50b2b08134ece8 439 Gene3D G3DSA:3.40.50.720 1 160 4.9E-36 T 29-03-2018 CDC59_RS08765 38985c81b09fec3c3a50b2b08134ece8 439 Gene3D G3DSA:3.30.70.260 353 434 1.2E-16 T 29-03-2018 CDC59_RS08765 38985c81b09fec3c3a50b2b08134ece8 439 SUPERFAMILY SSF55347 140 305 1.18E-52 T 29-03-2018 CDC59_RS08765 38985c81b09fec3c3a50b2b08134ece8 439 PIRSF PIRSF000098 1 438 7.5E-161 T 29-03-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CDC59_RS08765 38985c81b09fec3c3a50b2b08134ece8 439 Pfam PF00742 Homoserine dehydrogenase 140 318 8.8E-64 T 29-03-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CDC59_RS23965 bf42e3c830bc21e6ed2bd3d8df3739fb 422 Gene3D G3DSA:1.10.150.130 27 150 2.8E-9 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal CDC59_RS23965 bf42e3c830bc21e6ed2bd3d8df3739fb 422 Gene3D G3DSA:1.10.443.10 173 395 1.2E-7 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CDC59_RS23965 bf42e3c830bc21e6ed2bd3d8df3739fb 422 SUPERFAMILY SSF56349 33 234 1.88E-7 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CDC59_RS23965 bf42e3c830bc21e6ed2bd3d8df3739fb 422 SUPERFAMILY SSF56349 182 377 1.1E-5 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CDC59_RS19345 670b278fa0e33894e587b940f1d4d9f1 776 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 430 752 1.2E-150 T 29-03-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CDC59_RS19345 670b278fa0e33894e587b940f1d4d9f1 776 SUPERFAMILY SSF51726 5 393 3.4E-114 T 29-03-2018 CDC59_RS19345 670b278fa0e33894e587b940f1d4d9f1 776 Gene3D G3DSA:3.20.20.210 2 388 2.8E-146 T 29-03-2018 CDC59_RS19345 670b278fa0e33894e587b940f1d4d9f1 776 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 4 313 1.9E-119 T 29-03-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CDC59_RS19345 670b278fa0e33894e587b940f1d4d9f1 776 SUPERFAMILY SSF51726 395 756 1.83E-120 T 29-03-2018 CDC59_RS19345 670b278fa0e33894e587b940f1d4d9f1 776 Gene3D G3DSA:3.20.20.210 389 758 7.7E-131 T 29-03-2018 CDC59_RS19345 670b278fa0e33894e587b940f1d4d9f1 776 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 2 757 37.033 T 29-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CDC59_RS19345 670b278fa0e33894e587b940f1d4d9f1 776 PIRSF PIRSF000382 1 761 0.0 T 29-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CDC59_RS19345 670b278fa0e33894e587b940f1d4d9f1 776 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 7 756 0.0 T 29-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CDC59_RS10180 c3103f3e72eea9f07114809cca2435ae 217 Gene3D G3DSA:3.90.226.10 24 216 1.4E-46 T 29-03-2018 CDC59_RS10180 c3103f3e72eea9f07114809cca2435ae 217 PRINTS PR00127 Clp protease catalytic subunit P signature 112 129 3.0E-53 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CDC59_RS10180 c3103f3e72eea9f07114809cca2435ae 217 PRINTS PR00127 Clp protease catalytic subunit P signature 133 152 3.0E-53 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CDC59_RS10180 c3103f3e72eea9f07114809cca2435ae 217 PRINTS PR00127 Clp protease catalytic subunit P signature 190 209 3.0E-53 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CDC59_RS10180 c3103f3e72eea9f07114809cca2435ae 217 PRINTS PR00127 Clp protease catalytic subunit P signature 41 56 3.0E-53 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CDC59_RS10180 c3103f3e72eea9f07114809cca2435ae 217 PRINTS PR00127 Clp protease catalytic subunit P signature 81 101 3.0E-53 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CDC59_RS10180 c3103f3e72eea9f07114809cca2435ae 217 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 24 214 1.8E-105 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CDC59_RS10180 c3103f3e72eea9f07114809cca2435ae 217 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 25 215 45.085 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CDC59_RS10180 c3103f3e72eea9f07114809cca2435ae 217 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 134 147 - T 29-03-2018 IPR033135 ClpP, histidine active site CDC59_RS10180 c3103f3e72eea9f07114809cca2435ae 217 Pfam PF00574 Clp protease 35 214 5.8E-88 T 29-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CDC59_RS10180 c3103f3e72eea9f07114809cca2435ae 217 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 112 123 - T 29-03-2018 IPR018215 ClpP, Ser active site CDC59_RS10180 c3103f3e72eea9f07114809cca2435ae 217 SUPERFAMILY SSF52096 33 214 4.98E-75 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CDC59_RS14960 1184b74857125d75701177e8ac89d93f 201 Gene3D G3DSA:3.40.30.10 2 199 4.7E-49 T 29-03-2018 CDC59_RS14960 1184b74857125d75701177e8ac89d93f 201 Pfam PF01323 DSBA-like thioredoxin domain 5 196 4.5E-36 T 29-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 CDC59_RS14960 1184b74857125d75701177e8ac89d93f 201 PIRSF PIRSF006386 1 201 5.4E-60 T 29-03-2018 IPR014440 HCCA isomerase/glutathione S-transferase kappa Reactome: R-HSA-156590 CDC59_RS14960 1184b74857125d75701177e8ac89d93f 201 SUPERFAMILY SSF52833 4 198 3.1E-44 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS23500 aae4848f3e9b1b10a7de57d235ba484d 411 SUPERFAMILY SSF53335 161 396 1.25E-46 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS23500 aae4848f3e9b1b10a7de57d235ba484d 411 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 196 202 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CDC59_RS23500 aae4848f3e9b1b10a7de57d235ba484d 411 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 193 205 6.9E-18 T 29-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 CDC59_RS23500 aae4848f3e9b1b10a7de57d235ba484d 411 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 353 367 6.9E-18 T 29-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 CDC59_RS23500 aae4848f3e9b1b10a7de57d235ba484d 411 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 330 352 6.9E-18 T 29-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 CDC59_RS23500 aae4848f3e9b1b10a7de57d235ba484d 411 PIRSF PIRSF036758 8 411 1.8E-155 T 29-03-2018 IPR015840 DNA methyase, ParB domain-containing CDC59_RS23500 aae4848f3e9b1b10a7de57d235ba484d 411 SUPERFAMILY SSF110849 9 148 3.53E-32 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CDC59_RS23500 aae4848f3e9b1b10a7de57d235ba484d 411 SMART SM00470 11 97 1.3E-11 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CDC59_RS23500 aae4848f3e9b1b10a7de57d235ba484d 411 Pfam PF01555 DNA methylase 194 387 1.2E-20 T 29-03-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 CDC59_RS23500 aae4848f3e9b1b10a7de57d235ba484d 411 Gene3D G3DSA:3.90.1530.10 4 102 8.6E-14 T 29-03-2018 CDC59_RS23500 aae4848f3e9b1b10a7de57d235ba484d 411 Gene3D G3DSA:3.40.50.150 170 409 2.5E-38 T 29-03-2018 CDC59_RS23500 aae4848f3e9b1b10a7de57d235ba484d 411 Pfam PF02195 ParB-like nuclease domain 14 90 3.0E-11 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CDC59_RS09110 3d785a210154f6011b1cbb7d261e232c 1171 Gene3D G3DSA:3.40.50.300 1 173 3.6E-32 T 29-03-2018 CDC59_RS09110 3d785a210154f6011b1cbb7d261e232c 1171 Gene3D G3DSA:1.20.5.730 433 505 5.7E-4 T 29-03-2018 CDC59_RS09110 3d785a210154f6011b1cbb7d261e232c 1171 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1163 22.346 T 29-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 CDC59_RS09110 3d785a210154f6011b1cbb7d261e232c 1171 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 2 1161 0.0 T 29-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 CDC59_RS09110 3d785a210154f6011b1cbb7d261e232c 1171 Gene3D G3DSA:1.10.287.160 506 725 0.042 T 29-03-2018 CDC59_RS09110 3d785a210154f6011b1cbb7d261e232c 1171 Pfam PF06470 SMC proteins Flexible Hinge Domain 523 622 6.9E-7 T 29-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CDC59_RS09110 3d785a210154f6011b1cbb7d261e232c 1171 Gene3D G3DSA:1.20.5.340 296 399 7.0E-5 T 29-03-2018 CDC59_RS09110 3d785a210154f6011b1cbb7d261e232c 1171 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 1154 5.4E-64 T 29-03-2018 IPR003395 RecF/RecN/SMC, N-terminal CDC59_RS09110 3d785a210154f6011b1cbb7d261e232c 1171 Gene3D G3DSA:3.40.50.300 944 1158 1.8E-8 T 29-03-2018 CDC59_RS09110 3d785a210154f6011b1cbb7d261e232c 1171 PIRSF PIRSF005719 1 1170 1.1E-253 T 29-03-2018 IPR024704 Structural maintenance of chromosomes protein CDC59_RS09110 3d785a210154f6011b1cbb7d261e232c 1171 SUPERFAMILY SSF75553 485 672 7.06E-7 T 29-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CDC59_RS09110 3d785a210154f6011b1cbb7d261e232c 1171 SMART SM00968 518 625 4.3E-10 T 29-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CDC59_RS09110 3d785a210154f6011b1cbb7d261e232c 1171 Gene3D G3DSA:1.20.5.170 726 837 4.5E-4 T 29-03-2018 CDC59_RS09110 3d785a210154f6011b1cbb7d261e232c 1171 SUPERFAMILY SSF52540 2 213 1.11E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS09110 3d785a210154f6011b1cbb7d261e232c 1171 SUPERFAMILY SSF52540 1047 1162 1.11E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS09110 3d785a210154f6011b1cbb7d261e232c 1171 Gene3D G3DSA:1.10.287.620 174 295 0.0019 T 29-03-2018 CDC59_RS02145 7d16ab2c21fbe6433f11e84e0dd05777 231 PIRSF PIRSF002155 1 227 5.5E-78 T 29-03-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS02145 7d16ab2c21fbe6433f11e84e0dd05777 231 Gene3D G3DSA:3.40.50.790 68 149 4.8E-37 T 29-03-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich CDC59_RS02145 7d16ab2c21fbe6433f11e84e0dd05777 231 Gene3D G3DSA:3.30.190.20 150 228 1.7E-19 T 29-03-2018 CDC59_RS02145 7d16ab2c21fbe6433f11e84e0dd05777 231 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 228 2.5E-104 T 29-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 CDC59_RS02145 7d16ab2c21fbe6433f11e84e0dd05777 231 SUPERFAMILY SSF56808 6 225 1.19E-80 T 29-03-2018 IPR023674 Ribosomal protein L1-like CDC59_RS02145 7d16ab2c21fbe6433f11e84e0dd05777 231 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 42.994 T 29-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 CDC59_RS02145 7d16ab2c21fbe6433f11e84e0dd05777 231 Pfam PF00687 Ribosomal protein L1p/L10e family 31 220 3.1E-51 T 29-03-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein CDC59_RS02145 7d16ab2c21fbe6433f11e84e0dd05777 231 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 29-03-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS09250 42f22fc811df1fee1a8d31bd5f3bb93b 795 Pfam PF00391 PEP-utilising enzyme, mobile domain 389 460 4.9E-26 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CDC59_RS09250 42f22fc811df1fee1a8d31bd5f3bb93b 795 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 11 792 0.0 T 29-03-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484 CDC59_RS09250 42f22fc811df1fee1a8d31bd5f3bb93b 795 Gene3D G3DSA:3.20.20.60 485 795 2.6E-100 T 29-03-2018 CDC59_RS09250 42f22fc811df1fee1a8d31bd5f3bb93b 795 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 699 717 - T 29-03-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 CDC59_RS09250 42f22fc811df1fee1a8d31bd5f3bb93b 795 Gene3D G3DSA:3.50.30.10 363 484 1.7E-37 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CDC59_RS09250 42f22fc811df1fee1a8d31bd5f3bb93b 795 Gene3D G3DSA:3.30.470.20 200 362 2.1E-42 T 29-03-2018 CDC59_RS09250 42f22fc811df1fee1a8d31bd5f3bb93b 795 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 419 430 - T 29-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 CDC59_RS09250 42f22fc811df1fee1a8d31bd5f3bb93b 795 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 23 348 3.9E-117 T 29-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 CDC59_RS09250 42f22fc811df1fee1a8d31bd5f3bb93b 795 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 484 790 1.3E-60 T 29-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 CDC59_RS09250 42f22fc811df1fee1a8d31bd5f3bb93b 795 SUPERFAMILY SSF56059 9 390 1.41E-108 T 29-03-2018 CDC59_RS09250 42f22fc811df1fee1a8d31bd5f3bb93b 795 Gene3D G3DSA:3.30.1490.20 6 199 1.8E-56 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CDC59_RS09250 42f22fc811df1fee1a8d31bd5f3bb93b 795 PIRSF PIRSF000854 5 795 0.0 T 29-03-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484 CDC59_RS09250 42f22fc811df1fee1a8d31bd5f3bb93b 795 SUPERFAMILY SSF52009 356 470 2.49E-33 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CDC59_RS09250 42f22fc811df1fee1a8d31bd5f3bb93b 795 SUPERFAMILY SSF51621 469 792 1.05E-92 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CDC59_RS12665 4210535b3d189dbe077368524dfb73e0 148 SUPERFAMILY SSF51283 4 147 3.66E-50 T 29-03-2018 IPR029054 dUTPase-like CDC59_RS12665 4210535b3d189dbe077368524dfb73e0 148 TIGRFAM TIGR00576 dut: dUTP diphosphatase 10 147 2.0E-45 T 29-03-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|Reactome: R-HSA-499943 CDC59_RS12665 4210535b3d189dbe077368524dfb73e0 148 Pfam PF00692 dUTPase 15 146 6.8E-37 T 29-03-2018 IPR029054 dUTPase-like CDC59_RS12665 4210535b3d189dbe077368524dfb73e0 148 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 5 147 33.291 T 29-03-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|Reactome: R-HSA-499943 CDC59_RS12665 4210535b3d189dbe077368524dfb73e0 148 Gene3D G3DSA:2.70.40.10 1 112 9.9E-38 T 29-03-2018 CDC59_RS12665 4210535b3d189dbe077368524dfb73e0 148 Gene3D G3DSA:2.70.40.10 113 147 3.6E-13 T 29-03-2018 CDC59_RS15990 e3a413c8e0b6cb3ae2d65d1834fd6f04 448 ProSitePatterns PS00217 Sugar transport proteins signature 2. 144 169 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CDC59_RS15990 e3a413c8e0b6cb3ae2d65d1834fd6f04 448 SUPERFAMILY SSF103473 31 443 4.45E-67 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS15990 e3a413c8e0b6cb3ae2d65d1834fd6f04 448 Gene3D G3DSA:1.20.1250.20 27 236 8.3E-28 T 29-03-2018 CDC59_RS15990 e3a413c8e0b6cb3ae2d65d1834fd6f04 448 Gene3D G3DSA:1.20.1250.20 242 443 1.7E-23 T 29-03-2018 CDC59_RS15990 e3a413c8e0b6cb3ae2d65d1834fd6f04 448 Pfam PF00083 Sugar (and other) transporter 39 240 3.1E-28 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CDC59_RS15990 e3a413c8e0b6cb3ae2d65d1834fd6f04 448 Pfam PF07690 Major Facilitator Superfamily 271 443 5.6E-11 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDC59_RS15990 e3a413c8e0b6cb3ae2d65d1834fd6f04 448 ProSitePatterns PS00216 Sugar transport proteins signature 1. 313 330 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CDC59_RS01570 4f1a3d7aafd7c3466e1dff13d7ffde6c 321 Pfam PF13365 Trypsin-like peptidase domain 55 184 2.5E-25 T 29-03-2018 CDC59_RS01570 4f1a3d7aafd7c3466e1dff13d7ffde6c 321 PRINTS PR00834 HtrA/DegQ protease family signature 155 172 1.1E-18 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CDC59_RS01570 4f1a3d7aafd7c3466e1dff13d7ffde6c 321 PRINTS PR00834 HtrA/DegQ protease family signature 123 147 1.1E-18 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CDC59_RS01570 4f1a3d7aafd7c3466e1dff13d7ffde6c 321 PRINTS PR00834 HtrA/DegQ protease family signature 63 75 1.1E-18 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CDC59_RS01570 4f1a3d7aafd7c3466e1dff13d7ffde6c 321 PRINTS PR00834 HtrA/DegQ protease family signature 83 103 1.1E-18 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CDC59_RS01570 4f1a3d7aafd7c3466e1dff13d7ffde6c 321 PRINTS PR00834 HtrA/DegQ protease family signature 177 194 1.1E-18 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CDC59_RS01570 4f1a3d7aafd7c3466e1dff13d7ffde6c 321 Gene3D G3DSA:2.40.10.10 24 118 1.8E-12 T 29-03-2018 CDC59_RS01570 4f1a3d7aafd7c3466e1dff13d7ffde6c 321 SUPERFAMILY SSF50494 1 209 1.08E-36 T 29-03-2018 IPR009003 Peptidase S1, PA clan CDC59_RS01570 4f1a3d7aafd7c3466e1dff13d7ffde6c 321 Gene3D G3DSA:2.40.10.10 119 212 3.1E-22 T 29-03-2018 CDC59_RS14400 e1f19a0f6de6de0c45c1dfe770003469 134 Pfam PF02566 OsmC-like protein 33 126 8.4E-16 T 29-03-2018 IPR003718 OsmC/Ohr family CDC59_RS14400 e1f19a0f6de6de0c45c1dfe770003469 134 SUPERFAMILY SSF82784 3 121 2.09E-25 T 29-03-2018 IPR003718 OsmC/Ohr family CDC59_RS14400 e1f19a0f6de6de0c45c1dfe770003469 134 Gene3D G3DSA:3.30.300.20 1 131 2.6E-21 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CDC59_RS01235 00b695296cd9e2c696d4661f649a20b5 425 Gene3D G3DSA:3.50.50.60 10 415 1.0E-48 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS01235 00b695296cd9e2c696d4661f649a20b5 425 SUPERFAMILY SSF160996 205 360 1.02E-13 T 29-03-2018 CDC59_RS01235 00b695296cd9e2c696d4661f649a20b5 425 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 10 412 1.4E-86 T 29-03-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like CDC59_RS01235 00b695296cd9e2c696d4661f649a20b5 425 TIGRFAM TIGR03862 flavo_PP4765: flavoprotein, TIGR03862 family 30 419 3.6E-161 T 29-03-2018 IPR022460 Conserved hyptotheical protein CHP03862, flavoprotein, PP4765 CDC59_RS01235 00b695296cd9e2c696d4661f649a20b5 425 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 300 316 1.2E-8 T 29-03-2018 CDC59_RS01235 00b695296cd9e2c696d4661f649a20b5 425 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 9 31 1.2E-8 T 29-03-2018 CDC59_RS01235 00b695296cd9e2c696d4661f649a20b5 425 Pfam PF03486 HI0933-like protein 10 413 4.7E-116 T 29-03-2018 CDC59_RS01235 00b695296cd9e2c696d4661f649a20b5 425 SUPERFAMILY SSF51905 359 416 2.74E-43 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS01235 00b695296cd9e2c696d4661f649a20b5 425 SUPERFAMILY SSF51905 10 204 2.74E-43 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS08860 9630babf65a6ebad8ab250f83cd995ba 309 TIGRFAM TIGR02139 permease_CysT: sulfate ABC transporter, permease protein CysT 19 282 6.7E-130 T 29-03-2018 IPR011865 Sulphate ABC transporter, permease protein CysT GO:0008272|GO:0015116|GO:0016021 CDC59_RS08860 9630babf65a6ebad8ab250f83cd995ba 309 SUPERFAMILY SSF161098 25 276 1.78E-57 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS08860 9630babf65a6ebad8ab250f83cd995ba 309 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 17 278 7.0E-101 T 29-03-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 CDC59_RS08860 9630babf65a6ebad8ab250f83cd995ba 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 283 1.5E-27 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS08860 9630babf65a6ebad8ab250f83cd995ba 309 Gene3D G3DSA:1.10.3720.10 22 286 2.6E-50 T 29-03-2018 CDC59_RS19035 b336280896ff683d412785f8757e22e1 206 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 202 27.414 T 29-03-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 CDC59_RS19035 b336280896ff683d412785f8757e22e1 206 Gene3D G3DSA:3.40.50.360 3 206 3.0E-36 T 29-03-2018 IPR029039 Flavoprotein-like domain CDC59_RS19035 b336280896ff683d412785f8757e22e1 206 SUPERFAMILY SSF52218 1 202 2.74E-49 T 29-03-2018 IPR029039 Flavoprotein-like domain CDC59_RS19035 b336280896ff683d412785f8757e22e1 206 Pfam PF02525 Flavodoxin-like fold 3 200 7.8E-40 T 29-03-2018 IPR003680 Flavodoxin-like fold CDC59_RS06155 dbb5b4fc242a4234002f8ac9108fecb4 825 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 586 811 1.9E-38 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS06155 dbb5b4fc242a4234002f8ac9108fecb4 825 SUPERFAMILY SSF88659 720 821 4.3E-27 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS06155 dbb5b4fc242a4234002f8ac9108fecb4 825 Gene3D G3DSA:1.10.10.10 660 710 1.3E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS06155 dbb5b4fc242a4234002f8ac9108fecb4 825 PRINTS PR00046 Major sigma-70 factor signature 783 798 1.2E-30 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS06155 dbb5b4fc242a4234002f8ac9108fecb4 825 PRINTS PR00046 Major sigma-70 factor signature 762 774 1.2E-30 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS06155 dbb5b4fc242a4234002f8ac9108fecb4 825 PRINTS PR00046 Major sigma-70 factor signature 638 646 1.2E-30 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS06155 dbb5b4fc242a4234002f8ac9108fecb4 825 PRINTS PR00046 Major sigma-70 factor signature 798 809 1.2E-30 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS06155 dbb5b4fc242a4234002f8ac9108fecb4 825 PRINTS PR00046 Major sigma-70 factor signature 614 627 1.2E-30 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS06155 dbb5b4fc242a4234002f8ac9108fecb4 825 Pfam PF04546 Sigma-70, non-essential region 345 559 4.8E-67 T 29-03-2018 IPR007631 RNA polymerase sigma factor 70, non-essential domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS06155 dbb5b4fc242a4234002f8ac9108fecb4 825 Pfam PF04542 Sigma-70 region 2 592 659 9.6E-21 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS06155 dbb5b4fc242a4234002f8ac9108fecb4 825 Pfam PF04539 Sigma-70 region 3 669 745 3.0E-25 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS06155 dbb5b4fc242a4234002f8ac9108fecb4 825 Pfam PF03979 Sigma-70 factor, region 1.1 208 287 6.4E-28 T 29-03-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 CDC59_RS06155 dbb5b4fc242a4234002f8ac9108fecb4 825 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 783 809 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS06155 dbb5b4fc242a4234002f8ac9108fecb4 825 SUPERFAMILY SSF88946 321 657 4.84E-103 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS06155 dbb5b4fc242a4234002f8ac9108fecb4 825 SUPERFAMILY SSF88659 663 736 1.45E-18 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS06155 dbb5b4fc242a4234002f8ac9108fecb4 825 Gene3D G3DSA:1.10.10.10 753 823 1.8E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS06155 dbb5b4fc242a4234002f8ac9108fecb4 825 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 185 823 42.576 T 29-03-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 CDC59_RS06155 dbb5b4fc242a4234002f8ac9108fecb4 825 Pfam PF00140 Sigma-70 factor, region 1.2 304 336 1.0E-13 T 29-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS06155 dbb5b4fc242a4234002f8ac9108fecb4 825 Pfam PF04545 Sigma-70, region 4 758 811 4.9E-19 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS06155 dbb5b4fc242a4234002f8ac9108fecb4 825 Gene3D G3DSA:1.10.601.10 321 659 1.3E-107 T 29-03-2018 CDC59_RS06155 dbb5b4fc242a4234002f8ac9108fecb4 825 Gene3D G3DSA:1.10.601.10 128 320 7.2E-18 T 29-03-2018 CDC59_RS06155 dbb5b4fc242a4234002f8ac9108fecb4 825 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 614 627 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS06155 dbb5b4fc242a4234002f8ac9108fecb4 825 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 586 822 1.6E-118 T 29-03-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 CDC59_RS07435 d6d444be79ae375feb8b54615ca66724 237 Gene3D G3DSA:3.40.50.2300 1 125 2.3E-33 T 29-03-2018 CDC59_RS07435 d6d444be79ae375feb8b54615ca66724 237 SMART SM00448 3 115 3.4E-34 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS07435 d6d444be79ae375feb8b54615ca66724 237 Pfam PF00072 Response regulator receiver domain 5 115 4.0E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS07435 d6d444be79ae375feb8b54615ca66724 237 Gene3D G3DSA:1.10.10.10 126 234 3.1E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS07435 d6d444be79ae375feb8b54615ca66724 237 SMART SM00862 151 227 4.2E-18 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDC59_RS07435 d6d444be79ae375feb8b54615ca66724 237 SUPERFAMILY SSF52172 4 185 3.27E-34 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS07435 d6d444be79ae375feb8b54615ca66724 237 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 227 7.7E-18 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDC59_RS19330 dc9017041c00733396d8d429d86ccce1 227 Gene3D G3DSA:3.40.50.10070 43 184 1.1E-19 T 29-03-2018 CDC59_RS19330 dc9017041c00733396d8d429d86ccce1 227 Pfam PF03783 Curli production assembly/transport component CsgG 47 223 1.2E-31 T 29-03-2018 IPR005534 Curli production assembly/transport component CsgG GO:0030288 CDC59_RS19330 dc9017041c00733396d8d429d86ccce1 227 SUPERFAMILY SSF52964 48 146 7.06E-9 T 29-03-2018 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 CDC59_RS14620 2349bbd4bd1de8131828409b796b4a72 438 Gene3D G3DSA:1.10.8.60 318 396 1.5E-20 T 29-03-2018 CDC59_RS14620 2349bbd4bd1de8131828409b796b4a72 438 Gene3D G3DSA:3.40.50.300 141 317 6.1E-25 T 29-03-2018 CDC59_RS14620 2349bbd4bd1de8131828409b796b4a72 438 SMART SM00448 5 116 2.5E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS14620 2349bbd4bd1de8131828409b796b4a72 438 Pfam PF02954 Bacterial regulatory protein, Fis family 397 436 2.1E-10 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CDC59_RS14620 2349bbd4bd1de8131828409b796b4a72 438 SMART SM00382 165 308 1.7E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS14620 2349bbd4bd1de8131828409b796b4a72 438 SUPERFAMILY SSF52172 4 189 2.99E-41 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS14620 2349bbd4bd1de8131828409b796b4a72 438 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 419 438 3.8E-6 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CDC59_RS14620 2349bbd4bd1de8131828409b796b4a72 438 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 402 419 3.8E-6 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CDC59_RS14620 2349bbd4bd1de8131828409b796b4a72 438 SUPERFAMILY SSF52540 145 381 1.17E-66 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS14620 2349bbd4bd1de8131828409b796b4a72 438 Gene3D G3DSA:1.10.10.60 397 438 2.0E-15 T 29-03-2018 CDC59_RS14620 2349bbd4bd1de8131828409b796b4a72 438 Pfam PF00072 Response regulator receiver domain 7 116 1.5E-23 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS14620 2349bbd4bd1de8131828409b796b4a72 438 SUPERFAMILY SSF46689 386 438 1.99E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS14620 2349bbd4bd1de8131828409b796b4a72 438 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 358 367 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site CDC59_RS14620 2349bbd4bd1de8131828409b796b4a72 438 Gene3D G3DSA:3.40.50.2300 1 140 2.2E-30 T 29-03-2018 CDC59_RS14620 2349bbd4bd1de8131828409b796b4a72 438 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 231 246 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CDC59_RS14620 2349bbd4bd1de8131828409b796b4a72 438 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 169 182 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CDC59_RS14620 2349bbd4bd1de8131828409b796b4a72 438 Pfam PF00158 Sigma-54 interaction domain 145 311 3.6E-68 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CDC59_RS15900 41fb2b4ddf72721715bcf3335f3a53bc 172 Gene3D G3DSA:1.10.10.10 11 99 5.2E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS15900 41fb2b4ddf72721715bcf3335f3a53bc 172 SUPERFAMILY SSF46785 22 158 1.59E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS15900 41fb2b4ddf72721715bcf3335f3a53bc 172 Pfam PF01475 Ferric uptake regulator family 30 122 3.1E-9 T 29-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CDC59_RS15535 61e00dc24b2a64dbf2591aa2f0a6ddf0 106 Pfam PF01381 Helix-turn-helix 51 89 7.4E-7 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDC59_RS15535 61e00dc24b2a64dbf2591aa2f0a6ddf0 106 Gene3D G3DSA:1.10.260.40 49 101 2.2E-10 T 29-03-2018 CDC59_RS15535 61e00dc24b2a64dbf2591aa2f0a6ddf0 106 SUPERFAMILY SSF47413 50 103 1.45E-9 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDC59_RS18320 3f3e0c7a7a96f2760e046b729bd76a40 434 Gene3D G3DSA:1.20.1250.20 13 207 1.0E-21 T 29-03-2018 CDC59_RS18320 3f3e0c7a7a96f2760e046b729bd76a40 434 SUPERFAMILY SSF103473 15 420 4.97E-58 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS18320 3f3e0c7a7a96f2760e046b729bd76a40 434 Pfam PF07690 Major Facilitator Superfamily 31 379 2.0E-37 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDC59_RS18320 3f3e0c7a7a96f2760e046b729bd76a40 434 Gene3D G3DSA:1.20.1250.20 211 424 1.9E-23 T 29-03-2018 CDC59_RS15140 060fbce039000d8955f160e452c3c016 248 SUPERFAMILY SSF51182 11 106 2.1E-9 T 29-03-2018 IPR011051 RmlC-like cupin domain CDC59_RS15140 060fbce039000d8955f160e452c3c016 248 Gene3D G3DSA:1.10.10.60 138 199 6.7E-13 T 29-03-2018 CDC59_RS15140 060fbce039000d8955f160e452c3c016 248 SUPERFAMILY SSF46689 145 193 2.51E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS15140 060fbce039000d8955f160e452c3c016 248 Pfam PF12833 Helix-turn-helix domain 168 246 4.2E-19 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CDC59_RS15140 060fbce039000d8955f160e452c3c016 248 SUPERFAMILY SSF46689 198 247 9.86E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS15140 060fbce039000d8955f160e452c3c016 248 Gene3D G3DSA:1.10.10.60 200 247 2.4E-10 T 29-03-2018 CDC59_RS15140 060fbce039000d8955f160e452c3c016 248 Pfam PF14525 AraC-binding-like domain 11 129 1.7E-6 T 29-03-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like CDC59_RS15140 060fbce039000d8955f160e452c3c016 248 Gene3D G3DSA:2.60.120.10 7 96 1.0E-7 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CDC59_RS15140 060fbce039000d8955f160e452c3c016 248 SMART SM00342 162 245 7.7E-23 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CDC59_RS14340 c2752bee3774596216e69edd94154dee 447 Gene3D G3DSA:3.30.830.10 25 247 5.9E-35 T 29-03-2018 CDC59_RS14340 c2752bee3774596216e69edd94154dee 447 SUPERFAMILY SSF63411 262 445 2.33E-46 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CDC59_RS14340 c2752bee3774596216e69edd94154dee 447 SUPERFAMILY SSF63411 27 237 3.14E-36 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CDC59_RS14340 c2752bee3774596216e69edd94154dee 447 Gene3D G3DSA:3.30.830.10 256 447 5.2E-40 T 29-03-2018 CDC59_RS14340 c2752bee3774596216e69edd94154dee 447 Pfam PF05193 Peptidase M16 inactive domain 199 377 4.0E-35 T 29-03-2018 IPR007863 Peptidase M16, C-terminal CDC59_RS18595 e2e8e4d2fdda6a4d6f0219c132cc5d12 262 Gene3D G3DSA:1.10.3720.10 48 256 2.5E-43 T 29-03-2018 CDC59_RS18595 e2e8e4d2fdda6a4d6f0219c132cc5d12 262 SUPERFAMILY SSF161098 53 241 4.19E-45 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS18595 e2e8e4d2fdda6a4d6f0219c132cc5d12 262 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 72 256 6.5E-26 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS18595 e2e8e4d2fdda6a4d6f0219c132cc5d12 262 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 52 150 3.7E-26 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CDC59_RS18960 2cb900018d7a55def9f4cb7594b4b36d 95 TIGRFAM TIGR02157 PA_CoA_Oxy2: phenylacetate-CoA oxygenase, PaaH subunit 6 95 5.5E-44 T 29-03-2018 IPR009359 Phenylacetic acid degradation B CDC59_RS18960 2cb900018d7a55def9f4cb7594b4b36d 95 PIRSF PIRSF030200 1 95 1.3E-44 T 29-03-2018 IPR009359 Phenylacetic acid degradation B CDC59_RS18960 2cb900018d7a55def9f4cb7594b4b36d 95 Pfam PF06243 Phenylacetic acid degradation B 5 92 1.3E-39 T 29-03-2018 IPR009359 Phenylacetic acid degradation B CDC59_RS14585 da0698052c9d8b6c0c4f769eef3447fe 510 SUPERFAMILY SSF54211 10 177 1.52E-28 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CDC59_RS14585 da0698052c9d8b6c0c4f769eef3447fe 510 SUPERFAMILY SSF52540 197 505 1.98E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS14585 da0698052c9d8b6c0c4f769eef3447fe 510 Gene3D G3DSA:3.40.50.300 202 444 7.4E-22 T 29-03-2018 CDC59_RS14585 da0698052c9d8b6c0c4f769eef3447fe 510 Gene3D G3DSA:3.30.230.10 2 192 6.0E-43 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CDC59_RS14585 da0698052c9d8b6c0c4f769eef3447fe 510 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 299 313 7.1E-7 T 29-03-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 CDC59_RS14585 da0698052c9d8b6c0c4f769eef3447fe 510 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 327 340 7.1E-7 T 29-03-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 CDC59_RS14585 da0698052c9d8b6c0c4f769eef3447fe 510 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 351 363 7.1E-7 T 29-03-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 CDC59_RS14585 da0698052c9d8b6c0c4f769eef3447fe 510 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 219 234 7.1E-7 T 29-03-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 CDC59_RS14585 da0698052c9d8b6c0c4f769eef3447fe 510 SMART SM00382 220 402 6.7E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS14585 da0698052c9d8b6c0c4f769eef3447fe 510 Pfam PF01078 Magnesium chelatase, subunit ChlI 200 405 8.5E-98 T 29-03-2018 IPR000523 Magnesium chelatase ChlI domain CDC59_RS14585 da0698052c9d8b6c0c4f769eef3447fe 510 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 8 504 7.7E-178 T 29-03-2018 IPR004482 Mg chelatase-related protein CDC59_RS14585 da0698052c9d8b6c0c4f769eef3447fe 510 Pfam PF13541 Subunit ChlI of Mg-chelatase 21 129 4.9E-44 T 29-03-2018 CDC59_RS14585 da0698052c9d8b6c0c4f769eef3447fe 510 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 412 504 2.6E-27 T 29-03-2018 IPR025158 Mg chelatase-related protein, C-terminal domain CDC59_RS13165 ee87843f4fa4c237e78d271a5bd4d742 368 Pfam PF00107 Zinc-binding dehydrogenase 197 319 6.4E-26 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CDC59_RS13165 ee87843f4fa4c237e78d271a5bd4d742 368 SUPERFAMILY SSF51735 160 333 1.28E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS13165 ee87843f4fa4c237e78d271a5bd4d742 368 SMART SM00829 12 366 1.9E-4 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CDC59_RS13165 ee87843f4fa4c237e78d271a5bd4d742 368 Gene3D G3DSA:3.40.50.10730 181 312 2.3E-32 T 29-03-2018 CDC59_RS13165 ee87843f4fa4c237e78d271a5bd4d742 368 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CDC59_RS13165 ee87843f4fa4c237e78d271a5bd4d742 368 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 128 3.3E-23 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CDC59_RS13165 ee87843f4fa4c237e78d271a5bd4d742 368 SUPERFAMILY SSF50129 318 368 1.22E-12 T 29-03-2018 IPR011032 GroES-like CDC59_RS13165 ee87843f4fa4c237e78d271a5bd4d742 368 SUPERFAMILY SSF50129 1 185 7.91E-71 T 29-03-2018 IPR011032 GroES-like CDC59_RS13165 ee87843f4fa4c237e78d271a5bd4d742 368 TIGRFAM TIGR02818 adh_III_F_hyde: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 2 367 1.7E-191 T 29-03-2018 IPR014183 Alcohol dehydrogenase class III GO:0006069|GO:0008270|GO:0051903|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00620+1.1.1.28|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00680+1.1.1.284|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-1801|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6454|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-6901|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396|MetaCyc: PWY-7798|Reactome: R-HSA-71384 CDC59_RS13165 ee87843f4fa4c237e78d271a5bd4d742 368 Gene3D G3DSA:3.90.180.10 3 180 2.4E-49 T 29-03-2018 CDC59_RS04690 75aa30b5df44e92d7ff08f8120f102a4 1322 Pfam PF05567 Neisseria PilC beta-propeller domain 785 1133 1.4E-49 T 29-03-2018 IPR008707 PilC beta-propeller domain CDC59_RS06065 3c2693b563c30cf41cb5bdac83a205d2 334 Hamap MF_00301 Homoserine kinase [thrB]. 1 334 163.771 T 29-03-2018 IPR005280 Homoserine kinase, type II GO:0004413|GO:0009088 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CDC59_RS06065 3c2693b563c30cf41cb5bdac83a205d2 334 Gene3D G3DSA:3.90.1200.10 109 326 1.8E-22 T 29-03-2018 CDC59_RS06065 3c2693b563c30cf41cb5bdac83a205d2 334 Pfam PF01636 Phosphotransferase enzyme family 27 268 4.3E-34 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase CDC59_RS06065 3c2693b563c30cf41cb5bdac83a205d2 334 Gene3D G3DSA:3.30.200.20 2 106 6.5E-22 T 29-03-2018 CDC59_RS06065 3c2693b563c30cf41cb5bdac83a205d2 334 SUPERFAMILY SSF56112 5 320 1.11E-69 T 29-03-2018 IPR011009 Protein kinase-like domain CDC59_RS06065 3c2693b563c30cf41cb5bdac83a205d2 334 TIGRFAM TIGR00938 thrB_alt: homoserine kinase 1 317 9.4E-93 T 29-03-2018 IPR005280 Homoserine kinase, type II GO:0004413|GO:0009088 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CDC59_RS22615 15a2ca9f990ce5bf2ecb0437f33bdc46 294 Gene3D G3DSA:3.40.190.10 177 269 1.2E-18 T 29-03-2018 CDC59_RS22615 15a2ca9f990ce5bf2ecb0437f33bdc46 294 Gene3D G3DSA:1.10.10.10 1 85 6.5E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS22615 15a2ca9f990ce5bf2ecb0437f33bdc46 294 SUPERFAMILY SSF46785 1 112 8.16E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS22615 15a2ca9f990ce5bf2ecb0437f33bdc46 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 4.8E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS22615 15a2ca9f990ce5bf2ecb0437f33bdc46 294 Gene3D G3DSA:3.40.190.10 90 176 4.1E-23 T 29-03-2018 CDC59_RS22615 15a2ca9f990ce5bf2ecb0437f33bdc46 294 Pfam PF03466 LysR substrate binding domain 89 294 2.0E-36 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS22615 15a2ca9f990ce5bf2ecb0437f33bdc46 294 SUPERFAMILY SSF53850 90 294 7.83E-41 T 29-03-2018 CDC59_RS05295 3aaf212ff5bd60e05caa351ef61a2e5c 327 Pfam PF10123 Mu-like prophage I protein 32 322 8.9E-68 T 29-03-2018 IPR012106 Protease, Mu phage/prophage I type CDC59_RS05295 3aaf212ff5bd60e05caa351ef61a2e5c 327 Gene3D G3DSA:1.20.5.1000 164 239 4.1E-12 T 29-03-2018 CDC59_RS05295 3aaf212ff5bd60e05caa351ef61a2e5c 327 PIRSF PIRSF016624 4 229 5.3E-42 T 29-03-2018 IPR012106 Protease, Mu phage/prophage I type CDC59_RS05295 3aaf212ff5bd60e05caa351ef61a2e5c 327 PIRSF PIRSF016624 177 327 5.6E-10 T 29-03-2018 IPR012106 Protease, Mu phage/prophage I type CDC59_RS07915 2da68db36a5cfd237c8e30141320fbe9 259 Gene3D G3DSA:3.40.50.720 3 258 1.3E-38 T 29-03-2018 CDC59_RS07915 2da68db36a5cfd237c8e30141320fbe9 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 3.8E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS07915 2da68db36a5cfd237c8e30141320fbe9 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 3.8E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS07915 2da68db36a5cfd237c8e30141320fbe9 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 3.8E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS07915 2da68db36a5cfd237c8e30141320fbe9 259 SUPERFAMILY SSF51735 6 253 1.0E-60 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS07915 2da68db36a5cfd237c8e30141320fbe9 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 252 1.6E-83 T 29-03-2018 CDC59_RS07915 2da68db36a5cfd237c8e30141320fbe9 259 PIRSF PIRSF000094 1 258 8.4E-113 T 29-03-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CDC59_RS07000 f8b85e3b46385a13bd21bdf9fc964e4a 507 Gene3D G3DSA:3.90.1150.10 378 507 6.5E-19 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS07000 f8b85e3b46385a13bd21bdf9fc964e4a 507 SUPERFAMILY SSF53383 111 505 1.03E-77 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS07000 f8b85e3b46385a13bd21bdf9fc964e4a 507 SUPERFAMILY SSF46785 48 126 3.18E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS07000 f8b85e3b46385a13bd21bdf9fc964e4a 507 Gene3D G3DSA:1.10.10.10 46 117 7.4E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS07000 f8b85e3b46385a13bd21bdf9fc964e4a 507 SMART SM00345 56 115 5.2E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDC59_RS07000 f8b85e3b46385a13bd21bdf9fc964e4a 507 Gene3D G3DSA:3.40.640.10 165 377 9.2E-41 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDC59_RS07000 f8b85e3b46385a13bd21bdf9fc964e4a 507 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 75 89 2.1E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDC59_RS07000 f8b85e3b46385a13bd21bdf9fc964e4a 507 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 89 105 2.1E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDC59_RS07000 f8b85e3b46385a13bd21bdf9fc964e4a 507 Pfam PF00155 Aminotransferase class I and II 171 499 4.5E-35 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CDC59_RS07000 f8b85e3b46385a13bd21bdf9fc964e4a 507 Pfam PF00392 Bacterial regulatory proteins, gntR family 61 115 2.3E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDC59_RS07385 c295fdbf6a657c84a8fe4f8f6dc81047 263 TIGRFAM TIGR00559 pdxJ: pyridoxine 5'-phosphate synthase 12 244 3.2E-93 T 29-03-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 CDC59_RS07385 c295fdbf6a657c84a8fe4f8f6dc81047 263 Pfam PF03740 Pyridoxal phosphate biosynthesis protein PdxJ 12 244 3.2E-101 T 29-03-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 CDC59_RS07385 c295fdbf6a657c84a8fe4f8f6dc81047 263 Hamap MF_00279 Pyridoxine 5'-phosphate synthase [pdxJ]. 1 249 125.117 T 29-03-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 CDC59_RS07385 c295fdbf6a657c84a8fe4f8f6dc81047 263 Gene3D G3DSA:3.20.20.70 10 244 3.2E-102 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS07385 c295fdbf6a657c84a8fe4f8f6dc81047 263 SUPERFAMILY SSF63892 10 246 5.89E-97 T 29-03-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 CDC59_RS05465 f5c6ef9adb63a77cab14e21795846831 371 SUPERFAMILY SSF53850 104 287 1.52E-59 T 29-03-2018 CDC59_RS05465 f5c6ef9adb63a77cab14e21795846831 371 Pfam PF01817 Chorismate mutase type II 24 101 4.1E-23 T 29-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CDC59_RS05465 f5c6ef9adb63a77cab14e21795846831 371 ProSitePatterns PS00857 Prephenate dehydratase signature 1. 255 277 - T 29-03-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CDC59_RS05465 f5c6ef9adb63a77cab14e21795846831 371 Gene3D G3DSA:3.40.190.10 194 268 2.8E-25 T 29-03-2018 CDC59_RS05465 f5c6ef9adb63a77cab14e21795846831 371 SUPERFAMILY SSF55021 274 369 2.56E-27 T 29-03-2018 CDC59_RS05465 f5c6ef9adb63a77cab14e21795846831 371 SUPERFAMILY SSF48600 19 106 7.33E-21 T 29-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CDC59_RS05465 f5c6ef9adb63a77cab14e21795846831 371 Pfam PF01842 ACT domain 290 355 1.8E-8 T 29-03-2018 IPR002912 ACT domain CDC59_RS05465 f5c6ef9adb63a77cab14e21795846831 371 PIRSF PIRSF001500 13 371 1.4E-147 T 29-03-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CDC59_RS05465 f5c6ef9adb63a77cab14e21795846831 371 SMART SM00830 24 103 3.0E-29 T 29-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CDC59_RS05465 f5c6ef9adb63a77cab14e21795846831 371 Gene3D G3DSA:1.20.59.10 15 111 4.1E-33 T 29-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CDC59_RS05465 f5c6ef9adb63a77cab14e21795846831 371 Gene3D G3DSA:3.40.190.10 112 193 1.4E-33 T 29-03-2018 CDC59_RS05465 f5c6ef9adb63a77cab14e21795846831 371 TIGRFAM TIGR01807 CM_P2: chorismate mutase 20 93 4.8E-32 T 29-03-2018 IPR010957 Gamma/beta/epsilon proteobacterial P-protein, chorismate mutase domain GO:0004106|GO:0005737|GO:0009094 KEGG: 00400+5.4.99.5+4.2.1.51|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7432|MetaCyc: PWY-7626 CDC59_RS05465 f5c6ef9adb63a77cab14e21795846831 371 Gene3D G3DSA:3.30.70.260 281 371 6.2E-27 T 29-03-2018 CDC59_RS05465 f5c6ef9adb63a77cab14e21795846831 371 Pfam PF00800 Prephenate dehydratase 105 279 6.5E-62 T 29-03-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CDC59_RS06120 5abddfe40bfdb0d1684a165d17958784 299 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 82 98 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site CDC59_RS06120 5abddfe40bfdb0d1684a165d17958784 299 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 213 225 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site CDC59_RS06120 5abddfe40bfdb0d1684a165d17958784 299 SUPERFAMILY SSF48576 3 270 8.64E-83 T 29-03-2018 IPR008949 Isoprenoid synthase domain CDC59_RS06120 5abddfe40bfdb0d1684a165d17958784 299 Gene3D G3DSA:1.10.600.10 1 299 4.8E-81 T 29-03-2018 IPR008949 Isoprenoid synthase domain CDC59_RS06120 5abddfe40bfdb0d1684a165d17958784 299 Pfam PF00348 Polyprenyl synthetase 31 259 6.1E-53 T 29-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 CDC59_RS23215 33e24864fa9a2c031b1ce0ea4131d459 400 Gene3D G3DSA:3.40.50.150 107 374 2.5E-60 T 29-03-2018 CDC59_RS23215 33e24864fa9a2c031b1ce0ea4131d459 400 SUPERFAMILY SSF53335 120 375 7.17E-77 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS23215 33e24864fa9a2c031b1ce0ea4131d459 400 PIRSF PIRSF003085 11 391 2.9E-112 T 29-03-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 CDC59_RS23215 33e24864fa9a2c031b1ce0ea4131d459 400 Pfam PF02353 Mycolic acid cyclopropane synthetase 112 370 1.1E-85 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS21760 bae2ac5fb8f9b018c4753762542603d2 718 Gene3D G3DSA:3.40.720.10 6 705 1.2E-25 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CDC59_RS21760 bae2ac5fb8f9b018c4753762542603d2 718 SUPERFAMILY SSF53649 478 686 4.97E-18 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CDC59_RS21760 bae2ac5fb8f9b018c4753762542603d2 718 Pfam PF04185 Phosphoesterase family 212 685 1.7E-95 T 29-03-2018 IPR007312 Phosphoesterase GO:0016788 CDC59_RS21760 bae2ac5fb8f9b018c4753762542603d2 718 TIGRFAM TIGR03397 acid_phos_Burk: acid phosphatase, Burkholderia-type 212 714 9.6E-230 T 29-03-2018 IPR017768 Acid phosphatase, AcpA GO:0003993 CDC59_RS05065 fdc7fc51a968fd7a5e4744be07eb4db5 702 Gene3D G3DSA:2.40.170.20 182 701 4.4E-66 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CDC59_RS05065 fdc7fc51a968fd7a5e4744be07eb4db5 702 Pfam PF00593 TonB dependent receptor 290 700 1.6E-40 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CDC59_RS05065 fdc7fc51a968fd7a5e4744be07eb4db5 702 Gene3D G3DSA:2.170.130.10 32 181 3.6E-26 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CDC59_RS05065 fdc7fc51a968fd7a5e4744be07eb4db5 702 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 71 700 7.7E-103 T 29-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 CDC59_RS05065 fdc7fc51a968fd7a5e4744be07eb4db5 702 SUPERFAMILY SSF56935 33 700 1.16E-111 T 29-03-2018 CDC59_RS05065 fdc7fc51a968fd7a5e4744be07eb4db5 702 Pfam PF07715 TonB-dependent Receptor Plug Domain 69 169 1.9E-18 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CDC59_RS07805 aa2752a666cc028a683a8fb4e3134d22 883 Pfam PF05192 MutS domain III 286 575 1.9E-38 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CDC59_RS07805 aa2752a666cc028a683a8fb4e3134d22 883 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 703 719 - T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CDC59_RS07805 aa2752a666cc028a683a8fb4e3134d22 883 SMART SM00534 622 809 6.4E-114 T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CDC59_RS07805 aa2752a666cc028a683a8fb4e3134d22 883 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 21 871 24.782 T 29-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 CDC59_RS07805 aa2752a666cc028a683a8fb4e3134d22 883 PIRSF PIRSF037677 11 856 5.7E-148 T 29-03-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 CDC59_RS07805 aa2752a666cc028a683a8fb4e3134d22 883 Pfam PF05188 MutS domain II 142 268 6.3E-17 T 29-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 CDC59_RS07805 aa2752a666cc028a683a8fb4e3134d22 883 SUPERFAMILY SSF52540 583 813 3.76E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS07805 aa2752a666cc028a683a8fb4e3134d22 883 Gene3D G3DSA:1.10.1420.10 424 551 2.7E-32 T 29-03-2018 CDC59_RS07805 aa2752a666cc028a683a8fb4e3134d22 883 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 21 876 0.0 T 29-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 CDC59_RS07805 aa2752a666cc028a683a8fb4e3134d22 883 Gene3D G3DSA:3.40.1170.10 13 145 1.8E-46 T 29-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 CDC59_RS07805 aa2752a666cc028a683a8fb4e3134d22 883 Gene3D G3DSA:1.10.1420.10 281 423 5.6E-36 T 29-03-2018 CDC59_RS07805 aa2752a666cc028a683a8fb4e3134d22 883 Pfam PF01624 MutS domain I 22 133 2.3E-41 T 29-03-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 CDC59_RS07805 aa2752a666cc028a683a8fb4e3134d22 883 SMART SM00533 300 607 1.0E-93 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CDC59_RS07805 aa2752a666cc028a683a8fb4e3134d22 883 SUPERFAMILY SSF48334 284 580 8.37E-85 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CDC59_RS07805 aa2752a666cc028a683a8fb4e3134d22 883 SUPERFAMILY SSF55271 18 129 3.14E-42 T 29-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 CDC59_RS07805 aa2752a666cc028a683a8fb4e3134d22 883 SUPERFAMILY SSF53150 131 297 1.7E-32 T 29-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 CDC59_RS07805 aa2752a666cc028a683a8fb4e3134d22 883 Pfam PF05190 MutS family domain IV 444 535 6.9E-31 T 29-03-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 CDC59_RS07805 aa2752a666cc028a683a8fb4e3134d22 883 Gene3D G3DSA:3.40.50.300 583 825 1.7E-37 T 29-03-2018 CDC59_RS07805 aa2752a666cc028a683a8fb4e3134d22 883 Gene3D G3DSA:3.30.420.110 146 279 3.4E-21 T 29-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 CDC59_RS07805 aa2752a666cc028a683a8fb4e3134d22 883 Pfam PF00488 MutS domain V 626 811 2.0E-82 T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CDC59_RS05810 408ce7bc56319f493dbf7bd8bbf1556e 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS05810 408ce7bc56319f493dbf7bd8bbf1556e 328 Pfam PF05598 Transposase domain (DUF772) 51 126 6.0E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS23525 408ce7bc56319f493dbf7bd8bbf1556e 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS23525 408ce7bc56319f493dbf7bd8bbf1556e 328 Pfam PF05598 Transposase domain (DUF772) 51 126 6.0E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS18945 408ce7bc56319f493dbf7bd8bbf1556e 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS18945 408ce7bc56319f493dbf7bd8bbf1556e 328 Pfam PF05598 Transposase domain (DUF772) 51 126 6.0E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS12600 408ce7bc56319f493dbf7bd8bbf1556e 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS12600 408ce7bc56319f493dbf7bd8bbf1556e 328 Pfam PF05598 Transposase domain (DUF772) 51 126 6.0E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS18025 408ce7bc56319f493dbf7bd8bbf1556e 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS18025 408ce7bc56319f493dbf7bd8bbf1556e 328 Pfam PF05598 Transposase domain (DUF772) 51 126 6.0E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS11975 408ce7bc56319f493dbf7bd8bbf1556e 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS11975 408ce7bc56319f493dbf7bd8bbf1556e 328 Pfam PF05598 Transposase domain (DUF772) 51 126 6.0E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS21995 408ce7bc56319f493dbf7bd8bbf1556e 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS21995 408ce7bc56319f493dbf7bd8bbf1556e 328 Pfam PF05598 Transposase domain (DUF772) 51 126 6.0E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS05720 408ce7bc56319f493dbf7bd8bbf1556e 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS05720 408ce7bc56319f493dbf7bd8bbf1556e 328 Pfam PF05598 Transposase domain (DUF772) 51 126 6.0E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS21345 408ce7bc56319f493dbf7bd8bbf1556e 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS21345 408ce7bc56319f493dbf7bd8bbf1556e 328 Pfam PF05598 Transposase domain (DUF772) 51 126 6.0E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS17495 408ce7bc56319f493dbf7bd8bbf1556e 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS17495 408ce7bc56319f493dbf7bd8bbf1556e 328 Pfam PF05598 Transposase domain (DUF772) 51 126 6.0E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS00315 408ce7bc56319f493dbf7bd8bbf1556e 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS00315 408ce7bc56319f493dbf7bd8bbf1556e 328 Pfam PF05598 Transposase domain (DUF772) 51 126 6.0E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS11075 408ce7bc56319f493dbf7bd8bbf1556e 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS11075 408ce7bc56319f493dbf7bd8bbf1556e 328 Pfam PF05598 Transposase domain (DUF772) 51 126 6.0E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS22485 408ce7bc56319f493dbf7bd8bbf1556e 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS22485 408ce7bc56319f493dbf7bd8bbf1556e 328 Pfam PF05598 Transposase domain (DUF772) 51 126 6.0E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS01440 c501aa8df0f5e80330fc717391d18017 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS01440 c501aa8df0f5e80330fc717391d18017 328 Pfam PF05598 Transposase domain (DUF772) 51 126 6.0E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS20285 c501aa8df0f5e80330fc717391d18017 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS20285 c501aa8df0f5e80330fc717391d18017 328 Pfam PF05598 Transposase domain (DUF772) 51 126 6.0E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS17670 c501aa8df0f5e80330fc717391d18017 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS17670 c501aa8df0f5e80330fc717391d18017 328 Pfam PF05598 Transposase domain (DUF772) 51 126 6.0E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS23675 c501aa8df0f5e80330fc717391d18017 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS23675 c501aa8df0f5e80330fc717391d18017 328 Pfam PF05598 Transposase domain (DUF772) 51 126 6.0E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS18890 c501aa8df0f5e80330fc717391d18017 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS18890 c501aa8df0f5e80330fc717391d18017 328 Pfam PF05598 Transposase domain (DUF772) 51 126 6.0E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS17415 c501aa8df0f5e80330fc717391d18017 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS17415 c501aa8df0f5e80330fc717391d18017 328 Pfam PF05598 Transposase domain (DUF772) 51 126 6.0E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS11100 c501aa8df0f5e80330fc717391d18017 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS11100 c501aa8df0f5e80330fc717391d18017 328 Pfam PF05598 Transposase domain (DUF772) 51 126 6.0E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS10635 c501aa8df0f5e80330fc717391d18017 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS10635 c501aa8df0f5e80330fc717391d18017 328 Pfam PF05598 Transposase domain (DUF772) 51 126 6.0E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS06650 c501aa8df0f5e80330fc717391d18017 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS06650 c501aa8df0f5e80330fc717391d18017 328 Pfam PF05598 Transposase domain (DUF772) 51 126 6.0E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS11500 feb529bc077e2b255d6c871d458a01ce 298 Pfam PF13714 Phosphoenolpyruvate phosphomutase 13 257 8.7E-50 T 29-03-2018 CDC59_RS11500 feb529bc077e2b255d6c871d458a01ce 298 Gene3D G3DSA:3.20.20.60 5 298 1.9E-92 T 29-03-2018 CDC59_RS11500 feb529bc077e2b255d6c871d458a01ce 298 ProSitePatterns PS00161 Isocitrate lyase signature. 124 129 - T 29-03-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 CDC59_RS11500 feb529bc077e2b255d6c871d458a01ce 298 SUPERFAMILY SSF51621 6 292 1.35E-102 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CDC59_RS11500 feb529bc077e2b255d6c871d458a01ce 298 Hamap MF_01939 2-methylisocitrate lyase [prpB]. 7 295 50.535 T 29-03-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 CDC59_RS11500 feb529bc077e2b255d6c871d458a01ce 298 TIGRFAM TIGR02317 prpB: methylisocitrate lyase 10 294 1.7E-131 T 29-03-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 CDC59_RS02225 18e283868cc5fca00a4f06ffa4cb0fa8 396 PRINTS PR00315 GTP-binding elongation factor signature 94 105 7.6E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDC59_RS02225 18e283868cc5fca00a4f06ffa4cb0fa8 396 PRINTS PR00315 GTP-binding elongation factor signature 58 66 7.6E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDC59_RS02225 18e283868cc5fca00a4f06ffa4cb0fa8 396 PRINTS PR00315 GTP-binding elongation factor signature 78 88 7.6E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDC59_RS02225 18e283868cc5fca00a4f06ffa4cb0fa8 396 PRINTS PR00315 GTP-binding elongation factor signature 131 140 7.6E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDC59_RS02225 18e283868cc5fca00a4f06ffa4cb0fa8 396 PRINTS PR00315 GTP-binding elongation factor signature 14 27 7.6E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDC59_RS02225 18e283868cc5fca00a4f06ffa4cb0fa8 396 Gene3D G3DSA:3.40.50.300 1 74 4.0E-11 T 29-03-2018 CDC59_RS02225 18e283868cc5fca00a4f06ffa4cb0fa8 396 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 396 1.9E-230 T 29-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CDC59_RS02225 18e283868cc5fca00a4f06ffa4cb0fa8 396 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 60.609 T 29-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CDC59_RS02225 18e283868cc5fca00a4f06ffa4cb0fa8 396 Gene3D G3DSA:2.40.30.10 208 301 7.3E-32 T 29-03-2018 CDC59_RS02225 18e283868cc5fca00a4f06ffa4cb0fa8 396 SUPERFAMILY SSF52540 6 221 1.91E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS02225 18e283868cc5fca00a4f06ffa4cb0fa8 396 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 1.9E-59 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDC59_RS02225 18e283868cc5fca00a4f06ffa4cb0fa8 396 Pfam PF03144 Elongation factor Tu domain 2 227 296 2.6E-18 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CDC59_RS02225 18e283868cc5fca00a4f06ffa4cb0fa8 396 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site CDC59_RS02225 18e283868cc5fca00a4f06ffa4cb0fa8 396 SUPERFAMILY SSF50447 207 303 5.11E-31 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CDC59_RS02225 18e283868cc5fca00a4f06ffa4cb0fa8 396 SUPERFAMILY SSF50465 304 396 3.74E-36 T 29-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal CDC59_RS02225 18e283868cc5fca00a4f06ffa4cb0fa8 396 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 150 1.3E-15 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CDC59_RS02225 18e283868cc5fca00a4f06ffa4cb0fa8 396 Gene3D G3DSA:2.40.30.10 302 395 6.8E-33 T 29-03-2018 CDC59_RS02225 18e283868cc5fca00a4f06ffa4cb0fa8 396 Gene3D G3DSA:3.40.50.300 75 205 1.2E-31 T 29-03-2018 CDC59_RS02225 18e283868cc5fca00a4f06ffa4cb0fa8 396 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 1.4E-33 T 29-03-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal CDC59_RS02120 18e283868cc5fca00a4f06ffa4cb0fa8 396 PRINTS PR00315 GTP-binding elongation factor signature 94 105 7.6E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDC59_RS02120 18e283868cc5fca00a4f06ffa4cb0fa8 396 PRINTS PR00315 GTP-binding elongation factor signature 58 66 7.6E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDC59_RS02120 18e283868cc5fca00a4f06ffa4cb0fa8 396 PRINTS PR00315 GTP-binding elongation factor signature 78 88 7.6E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDC59_RS02120 18e283868cc5fca00a4f06ffa4cb0fa8 396 PRINTS PR00315 GTP-binding elongation factor signature 131 140 7.6E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDC59_RS02120 18e283868cc5fca00a4f06ffa4cb0fa8 396 PRINTS PR00315 GTP-binding elongation factor signature 14 27 7.6E-25 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDC59_RS02120 18e283868cc5fca00a4f06ffa4cb0fa8 396 Gene3D G3DSA:3.40.50.300 1 74 4.0E-11 T 29-03-2018 CDC59_RS02120 18e283868cc5fca00a4f06ffa4cb0fa8 396 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 396 1.9E-230 T 29-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CDC59_RS02120 18e283868cc5fca00a4f06ffa4cb0fa8 396 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 60.609 T 29-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CDC59_RS02120 18e283868cc5fca00a4f06ffa4cb0fa8 396 Gene3D G3DSA:2.40.30.10 208 301 7.3E-32 T 29-03-2018 CDC59_RS02120 18e283868cc5fca00a4f06ffa4cb0fa8 396 SUPERFAMILY SSF52540 6 221 1.91E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS02120 18e283868cc5fca00a4f06ffa4cb0fa8 396 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 1.9E-59 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDC59_RS02120 18e283868cc5fca00a4f06ffa4cb0fa8 396 Pfam PF03144 Elongation factor Tu domain 2 227 296 2.6E-18 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CDC59_RS02120 18e283868cc5fca00a4f06ffa4cb0fa8 396 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site CDC59_RS02120 18e283868cc5fca00a4f06ffa4cb0fa8 396 SUPERFAMILY SSF50447 207 303 5.11E-31 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CDC59_RS02120 18e283868cc5fca00a4f06ffa4cb0fa8 396 SUPERFAMILY SSF50465 304 396 3.74E-36 T 29-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal CDC59_RS02120 18e283868cc5fca00a4f06ffa4cb0fa8 396 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 150 1.3E-15 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CDC59_RS02120 18e283868cc5fca00a4f06ffa4cb0fa8 396 Gene3D G3DSA:2.40.30.10 302 395 6.8E-33 T 29-03-2018 CDC59_RS02120 18e283868cc5fca00a4f06ffa4cb0fa8 396 Gene3D G3DSA:3.40.50.300 75 205 1.2E-31 T 29-03-2018 CDC59_RS02120 18e283868cc5fca00a4f06ffa4cb0fa8 396 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 1.4E-33 T 29-03-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal CDC59_RS20295 fc91d4afbd00662ded6ec90f4692b0c6 138 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 131 1.8E-14 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CDC59_RS20295 fc91d4afbd00662ded6ec90f4692b0c6 138 SUPERFAMILY SSF54593 7 135 2.82E-27 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CDC59_RS20295 fc91d4afbd00662ded6ec90f4692b0c6 138 Gene3D G3DSA:3.10.180.10 4 135 9.4E-26 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CDC59_RS22795 dfe31706504178c4793a4a74d5bd132c 384 Gene3D G3DSA:1.10.760.10 249 374 3.8E-20 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS22795 dfe31706504178c4793a4a74d5bd132c 384 Pfam PF00034 Cytochrome c 283 372 4.3E-9 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS22795 dfe31706504178c4793a4a74d5bd132c 384 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 188 236 - T 29-03-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS22795 dfe31706504178c4793a4a74d5bd132c 384 PRINTS PR01166 Cytochrome c oxidase subunit II signature 111 130 5.3E-8 T 29-03-2018 CDC59_RS22795 dfe31706504178c4793a4a74d5bd132c 384 PRINTS PR01166 Cytochrome c oxidase subunit II signature 163 184 5.3E-8 T 29-03-2018 CDC59_RS22795 dfe31706504178c4793a4a74d5bd132c 384 PRINTS PR01166 Cytochrome c oxidase subunit II signature 225 242 5.3E-8 T 29-03-2018 CDC59_RS22795 dfe31706504178c4793a4a74d5bd132c 384 PRINTS PR01166 Cytochrome c oxidase subunit II signature 187 207 5.3E-8 T 29-03-2018 CDC59_RS22795 dfe31706504178c4793a4a74d5bd132c 384 SUPERFAMILY SSF49503 165 316 8.71E-42 T 29-03-2018 IPR008972 Cupredoxin CDC59_RS22795 dfe31706504178c4793a4a74d5bd132c 384 SUPERFAMILY SSF49503 110 134 8.71E-42 T 29-03-2018 IPR008972 Cupredoxin CDC59_RS22795 dfe31706504178c4793a4a74d5bd132c 384 SUPERFAMILY SSF46626 282 372 7.2E-18 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS22795 dfe31706504178c4793a4a74d5bd132c 384 Gene3D G3DSA:1.10.287.90 18 111 8.0E-10 T 29-03-2018 CDC59_RS22795 dfe31706504178c4793a4a74d5bd132c 384 Gene3D G3DSA:2.60.40.420 113 248 1.0E-36 T 29-03-2018 IPR008972 Cupredoxin CDC59_RS22795 dfe31706504178c4793a4a74d5bd132c 384 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 116 240 3.1E-13 T 29-03-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS06720 aee6a6128fd4de0ec3c3e59ba371aa7c 84 Pfam PF00886 Ribosomal protein S16 8 68 2.0E-23 T 29-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS06720 aee6a6128fd4de0ec3c3e59ba371aa7c 84 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 1 78 22.772 T 29-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS06720 aee6a6128fd4de0ec3c3e59ba371aa7c 84 TIGRFAM TIGR00002 S16: ribosomal protein bS16 2 77 1.9E-26 T 29-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS06720 aee6a6128fd4de0ec3c3e59ba371aa7c 84 SUPERFAMILY SSF54565 1 76 2.62E-28 T 29-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS06720 aee6a6128fd4de0ec3c3e59ba371aa7c 84 Gene3D G3DSA:3.30.1320.10 1 79 5.9E-31 T 29-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS10355 c1d99c9eb463e037a6ef5013dead9ae3 712 SMART SM00491 535 665 5.3E-41 T 29-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CDC59_RS10355 c1d99c9eb463e037a6ef5013dead9ae3 712 SUPERFAMILY SSF52540 219 262 1.74E-10 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS10355 c1d99c9eb463e037a6ef5013dead9ae3 712 SUPERFAMILY SSF52540 506 604 1.74E-10 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS10355 c1d99c9eb463e037a6ef5013dead9ae3 712 SUPERFAMILY SSF52540 335 350 1.74E-10 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS10355 c1d99c9eb463e037a6ef5013dead9ae3 712 SUPERFAMILY SSF52540 635 652 1.74E-10 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS10355 c1d99c9eb463e037a6ef5013dead9ae3 712 SUPERFAMILY SSF52540 25 142 3.48E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS10355 c1d99c9eb463e037a6ef5013dead9ae3 712 SUPERFAMILY SSF52540 219 276 3.48E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS10355 c1d99c9eb463e037a6ef5013dead9ae3 712 SUPERFAMILY SSF52540 624 662 3.48E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS10355 c1d99c9eb463e037a6ef5013dead9ae3 712 Gene3D G3DSA:3.40.50.300 52 480 2.8E-27 T 29-03-2018 CDC59_RS10355 c1d99c9eb463e037a6ef5013dead9ae3 712 Gene3D G3DSA:3.40.50.300 500 688 7.3E-13 T 29-03-2018 CDC59_RS10355 c1d99c9eb463e037a6ef5013dead9ae3 712 Pfam PF13307 Helicase C-terminal domain 516 678 4.9E-33 T 29-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CDC59_RS07115 d73ff8508ad48c9adacaa5590204fc56 315 PRINTS PR00990 Ribokinase signature 44 63 6.8E-35 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CDC59_RS07115 d73ff8508ad48c9adacaa5590204fc56 315 PRINTS PR00990 Ribokinase signature 185 200 6.8E-35 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CDC59_RS07115 d73ff8508ad48c9adacaa5590204fc56 315 PRINTS PR00990 Ribokinase signature 17 38 6.8E-35 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CDC59_RS07115 d73ff8508ad48c9adacaa5590204fc56 315 PRINTS PR00990 Ribokinase signature 229 240 6.8E-35 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CDC59_RS07115 d73ff8508ad48c9adacaa5590204fc56 315 PRINTS PR00990 Ribokinase signature 116 129 6.8E-35 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CDC59_RS07115 d73ff8508ad48c9adacaa5590204fc56 315 TIGRFAM TIGR02152 D_ribokin_bact: ribokinase 15 311 5.2E-114 T 29-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 CDC59_RS07115 d73ff8508ad48c9adacaa5590204fc56 315 Hamap MF_01987 Ribokinase [rbsK]. 13 313 26.379 T 29-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 CDC59_RS07115 d73ff8508ad48c9adacaa5590204fc56 315 Gene3D G3DSA:3.40.1190.20 11 315 1.9E-86 T 29-03-2018 IPR029056 Ribokinase-like CDC59_RS07115 d73ff8508ad48c9adacaa5590204fc56 315 SUPERFAMILY SSF53613 14 312 1.71E-84 T 29-03-2018 IPR029056 Ribokinase-like CDC59_RS07115 d73ff8508ad48c9adacaa5590204fc56 315 Pfam PF00294 pfkB family carbohydrate kinase 13 305 2.4E-72 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB CDC59_RS02535 bcf09142c3379aa45d05500a1faa1a67 269 PRINTS PR01805 VacJ lipoprotein signature 105 122 6.0E-25 T 29-03-2018 IPR007428 MlaA lipoprotein GO:0016020 CDC59_RS02535 bcf09142c3379aa45d05500a1faa1a67 269 PRINTS PR01805 VacJ lipoprotein signature 141 158 6.0E-25 T 29-03-2018 IPR007428 MlaA lipoprotein GO:0016020 CDC59_RS02535 bcf09142c3379aa45d05500a1faa1a67 269 PRINTS PR01805 VacJ lipoprotein signature 54 70 6.0E-25 T 29-03-2018 IPR007428 MlaA lipoprotein GO:0016020 CDC59_RS02535 bcf09142c3379aa45d05500a1faa1a67 269 PRINTS PR01805 VacJ lipoprotein signature 37 50 6.0E-25 T 29-03-2018 IPR007428 MlaA lipoprotein GO:0016020 CDC59_RS02535 bcf09142c3379aa45d05500a1faa1a67 269 Pfam PF04333 MlaA lipoprotein 36 228 7.0E-80 T 29-03-2018 IPR007428 MlaA lipoprotein GO:0016020 CDC59_RS01420 87c991a68b6bacc0d0a638cf2d389c53 65 Gene3D G3DSA:3.90.820.10 2 65 2.3E-27 T 29-03-2018 CDC59_RS01420 87c991a68b6bacc0d0a638cf2d389c53 65 SMART SM00923 3 53 1.9E-18 T 29-03-2018 IPR005153 MbtH-like protein CDC59_RS01420 87c991a68b6bacc0d0a638cf2d389c53 65 SUPERFAMILY SSF160582 1 64 1.16E-24 T 29-03-2018 CDC59_RS01420 87c991a68b6bacc0d0a638cf2d389c53 65 Pfam PF03621 MbtH-like protein 1 52 8.7E-20 T 29-03-2018 IPR005153 MbtH-like protein CDC59_RS16595 87c991a68b6bacc0d0a638cf2d389c53 65 Gene3D G3DSA:3.90.820.10 2 65 2.3E-27 T 29-03-2018 CDC59_RS16595 87c991a68b6bacc0d0a638cf2d389c53 65 SMART SM00923 3 53 1.9E-18 T 29-03-2018 IPR005153 MbtH-like protein CDC59_RS16595 87c991a68b6bacc0d0a638cf2d389c53 65 SUPERFAMILY SSF160582 1 64 1.16E-24 T 29-03-2018 CDC59_RS16595 87c991a68b6bacc0d0a638cf2d389c53 65 Pfam PF03621 MbtH-like protein 1 52 8.7E-20 T 29-03-2018 IPR005153 MbtH-like protein CDC59_RS08910 e911b83196ffa9208477f6cf797d1b5c 151 SUPERFAMILY SSF110857 8 138 1.57E-28 T 29-03-2018 IPR013024 Gamma-glutamyl cyclotransferase-like CDC59_RS08910 e911b83196ffa9208477f6cf797d1b5c 151 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 9 132 3.1E-20 T 29-03-2018 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like CDC59_RS08910 e911b83196ffa9208477f6cf797d1b5c 151 Gene3D G3DSA:3.10.490.10 2 146 6.8E-29 T 29-03-2018 CDC59_RS01230 c74978f1e13dad6de93b5b424d06fc1a 278 Pfam PF13679 Methyltransferase domain 35 177 1.8E-43 T 29-03-2018 IPR025714 Methyltransferase domain CDC59_RS01230 c74978f1e13dad6de93b5b424d06fc1a 278 Gene3D G3DSA:3.40.50.150 28 257 6.0E-6 T 29-03-2018 CDC59_RS01230 c74978f1e13dad6de93b5b424d06fc1a 278 SUPERFAMILY SSF53335 40 194 7.01E-13 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS02055 12c204bf532fc177b37c1932374384c8 372 SMART SM00382 27 212 2.1E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS02055 12c204bf532fc177b37c1932374384c8 372 SUPERFAMILY SSF52540 2 241 2.08E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS02055 12c204bf532fc177b37c1932374384c8 372 Pfam PF00005 ABC transporter 21 160 1.2E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS02055 12c204bf532fc177b37c1932374384c8 372 SUPERFAMILY SSF50331 236 360 8.99E-21 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CDC59_RS02055 12c204bf532fc177b37c1932374384c8 372 Gene3D G3DSA:3.40.50.300 1 238 4.7E-57 T 29-03-2018 CDC59_RS02055 12c204bf532fc177b37c1932374384c8 372 Gene3D G3DSA:2.40.50.100 239 284 4.9E-5 T 29-03-2018 CDC59_RS02055 12c204bf532fc177b37c1932374384c8 372 Gene3D G3DSA:2.40.50.140 285 346 2.3E-9 T 29-03-2018 CDC59_RS02055 12c204bf532fc177b37c1932374384c8 372 Pfam PF08402 TOBE domain 275 353 2.4E-4 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CDC59_RS06690 192e313aa7529943b4e46db644a22171 165 Gene3D G3DSA:3.30.70.920 64 157 2.1E-25 T 29-03-2018 CDC59_RS06690 192e313aa7529943b4e46db644a22171 165 SUPERFAMILY SSF54909 73 158 1.15E-20 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CDC59_RS06690 192e313aa7529943b4e46db644a22171 165 SMART SM00344 11 120 3.0E-43 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CDC59_RS06690 192e313aa7529943b4e46db644a22171 165 Pfam PF01037 Lrp/AsnC ligand binding domain 77 151 2.2E-20 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CDC59_RS06690 192e313aa7529943b4e46db644a22171 165 SUPERFAMILY SSF46785 10 70 8.38E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS06690 192e313aa7529943b4e46db644a22171 165 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 27 38 2.5E-17 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CDC59_RS06690 192e313aa7529943b4e46db644a22171 165 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 38 57 2.5E-17 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CDC59_RS06690 192e313aa7529943b4e46db644a22171 165 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 11 27 2.5E-17 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CDC59_RS06690 192e313aa7529943b4e46db644a22171 165 Pfam PF13404 AsnC-type helix-turn-helix domain 11 52 6.8E-18 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CDC59_RS06690 192e313aa7529943b4e46db644a22171 165 Gene3D G3DSA:1.10.10.10 5 61 4.9E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS16465 fe0a317c117c04941cbca0f3344dc49d 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS16465 fe0a317c117c04941cbca0f3344dc49d 328 Pfam PF05598 Transposase domain (DUF772) 51 126 5.1E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS14940 fe0a317c117c04941cbca0f3344dc49d 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS14940 fe0a317c117c04941cbca0f3344dc49d 328 Pfam PF05598 Transposase domain (DUF772) 51 126 5.1E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS18525 fe0a317c117c04941cbca0f3344dc49d 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS18525 fe0a317c117c04941cbca0f3344dc49d 328 Pfam PF05598 Transposase domain (DUF772) 51 126 5.1E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS11250 fe0a317c117c04941cbca0f3344dc49d 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS11250 fe0a317c117c04941cbca0f3344dc49d 328 Pfam PF05598 Transposase domain (DUF772) 51 126 5.1E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS22345 fe0a317c117c04941cbca0f3344dc49d 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS22345 fe0a317c117c04941cbca0f3344dc49d 328 Pfam PF05598 Transposase domain (DUF772) 51 126 5.1E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS12000 fe0a317c117c04941cbca0f3344dc49d 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS12000 fe0a317c117c04941cbca0f3344dc49d 328 Pfam PF05598 Transposase domain (DUF772) 51 126 5.1E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS01365 fe0a317c117c04941cbca0f3344dc49d 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS01365 fe0a317c117c04941cbca0f3344dc49d 328 Pfam PF05598 Transposase domain (DUF772) 51 126 5.1E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS06080 7e53d5dc74185476a1b1c99328b21975 944 SMART SM00474 334 525 1.6E-32 T 29-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 CDC59_RS06080 7e53d5dc74185476a1b1c99328b21975 944 Gene3D G3DSA:3.30.70.370 762 944 8.8E-47 T 29-03-2018 CDC59_RS06080 7e53d5dc74185476a1b1c99328b21975 944 Gene3D G3DSA:3.30.70.370 665 756 3.4E-16 T 29-03-2018 CDC59_RS06080 7e53d5dc74185476a1b1c99328b21975 944 SMART SM00279 172 207 1.4E-13 T 29-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 CDC59_RS06080 7e53d5dc74185476a1b1c99328b21975 944 Pfam PF00476 DNA polymerase family A 558 942 1.4E-148 T 29-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDC59_RS06080 7e53d5dc74185476a1b1c99328b21975 944 Gene3D G3DSA:3.30.420.10 324 550 1.2E-45 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDC59_RS06080 7e53d5dc74185476a1b1c99328b21975 944 ProSitePatterns PS00447 DNA polymerase family A signature. 762 781 - T 29-03-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDC59_RS06080 7e53d5dc74185476a1b1c99328b21975 944 Pfam PF01612 3'-5' exonuclease 334 524 9.7E-38 T 29-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 CDC59_RS06080 7e53d5dc74185476a1b1c99328b21975 944 Gene3D G3DSA:1.10.150.20 184 260 3.7E-22 T 29-03-2018 CDC59_RS06080 7e53d5dc74185476a1b1c99328b21975 944 SUPERFAMILY SSF56672 531 944 9.9E-156 T 29-03-2018 CDC59_RS06080 7e53d5dc74185476a1b1c99328b21975 944 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 8 169 1.4E-53 T 29-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 CDC59_RS06080 7e53d5dc74185476a1b1c99328b21975 944 PRINTS PR00868 DNA-polymerase family A (pol I) signature 708 731 3.7E-70 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDC59_RS06080 7e53d5dc74185476a1b1c99328b21975 944 PRINTS PR00868 DNA-polymerase family A (pol I) signature 853 869 3.7E-70 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDC59_RS06080 7e53d5dc74185476a1b1c99328b21975 944 PRINTS PR00868 DNA-polymerase family A (pol I) signature 762 787 3.7E-70 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDC59_RS06080 7e53d5dc74185476a1b1c99328b21975 944 PRINTS PR00868 DNA-polymerase family A (pol I) signature 686 701 3.7E-70 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDC59_RS06080 7e53d5dc74185476a1b1c99328b21975 944 PRINTS PR00868 DNA-polymerase family A (pol I) signature 799 810 3.7E-70 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDC59_RS06080 7e53d5dc74185476a1b1c99328b21975 944 PRINTS PR00868 DNA-polymerase family A (pol I) signature 663 685 3.7E-70 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDC59_RS06080 7e53d5dc74185476a1b1c99328b21975 944 PRINTS PR00868 DNA-polymerase family A (pol I) signature 821 832 3.7E-70 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDC59_RS06080 7e53d5dc74185476a1b1c99328b21975 944 PRINTS PR00868 DNA-polymerase family A (pol I) signature 738 751 3.7E-70 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDC59_RS06080 7e53d5dc74185476a1b1c99328b21975 944 SMART SM00482 694 908 3.0E-111 T 29-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDC59_RS06080 7e53d5dc74185476a1b1c99328b21975 944 SMART SM00475 4 271 6.0E-111 T 29-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 CDC59_RS06080 7e53d5dc74185476a1b1c99328b21975 944 Gene3D G3DSA:1.20.1060.10 551 664 2.0E-36 T 29-03-2018 CDC59_RS06080 7e53d5dc74185476a1b1c99328b21975 944 SUPERFAMILY SSF47807 170 286 3.59E-31 T 29-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CDC59_RS06080 7e53d5dc74185476a1b1c99328b21975 944 TIGRFAM TIGR00593 pola: DNA polymerase I 8 944 9.7E-276 T 29-03-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDC59_RS06080 7e53d5dc74185476a1b1c99328b21975 944 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 170 256 7.0E-24 T 29-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CDC59_RS06080 7e53d5dc74185476a1b1c99328b21975 944 SUPERFAMILY SSF53098 337 526 8.54E-50 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDC59_RS06080 7e53d5dc74185476a1b1c99328b21975 944 SUPERFAMILY SSF88723 5 169 1.09E-56 T 29-03-2018 IPR029060 PIN domain-like CDC59_RS06080 7e53d5dc74185476a1b1c99328b21975 944 Gene3D G3DSA:3.40.50.1010 6 183 1.1E-67 T 29-03-2018 IPR029060 PIN domain-like CDC59_RS08180 b77952415899088ec21c8e34849887dd 447 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 4 156 1.4E-17 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CDC59_RS08180 b77952415899088ec21c8e34849887dd 447 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 181 346 2.4E-25 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CDC59_RS08180 b77952415899088ec21c8e34849887dd 447 PIRSF PIRSF006485 1 444 2.1E-166 T 29-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 CDC59_RS08180 b77952415899088ec21c8e34849887dd 447 Gene3D G3DSA:3.30.300.20 371 437 2.4E-25 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CDC59_RS08180 b77952415899088ec21c8e34849887dd 447 Pfam PF01926 50S ribosome-binding GTPase 5 120 8.7E-25 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CDC59_RS08180 b77952415899088ec21c8e34849887dd 447 Pfam PF01926 50S ribosome-binding GTPase 182 300 1.0E-24 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CDC59_RS08180 b77952415899088ec21c8e34849887dd 447 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 3 436 1.0E-167 T 29-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 CDC59_RS08180 b77952415899088ec21c8e34849887dd 447 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 73 91 3.4E-8 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CDC59_RS08180 b77952415899088ec21c8e34849887dd 447 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 3.4E-8 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CDC59_RS08180 b77952415899088ec21c8e34849887dd 447 SUPERFAMILY SSF52540 138 442 9.2E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS08180 b77952415899088ec21c8e34849887dd 447 SUPERFAMILY SSF52540 4 164 4.94E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS08180 b77952415899088ec21c8e34849887dd 447 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 356 436 1.0E-24 T 29-03-2018 IPR032859 GTPase Der, C-terminal KH-domain-like CDC59_RS08180 b77952415899088ec21c8e34849887dd 447 SMART SM00382 179 322 4.1E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS08180 b77952415899088ec21c8e34849887dd 447 SMART SM00382 1 140 3.1 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS08180 b77952415899088ec21c8e34849887dd 447 Gene3D G3DSA:1.20.120.430 248 370 4.9E-11 T 29-03-2018 CDC59_RS08180 b77952415899088ec21c8e34849887dd 447 Hamap MF_00195 GTPase Der [der]. 2 439 37.356 T 29-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 CDC59_RS08180 b77952415899088ec21c8e34849887dd 447 Gene3D G3DSA:1.20.120.430 68 247 5.1E-45 T 29-03-2018 CDC59_RS08180 b77952415899088ec21c8e34849887dd 447 Gene3D G3DSA:1.20.120.430 1 67 1.4E-13 T 29-03-2018 CDC59_RS02435 6194facfd1d5d6f8fed3922d5290bad1 419 PRINTS PR01181 Diaminopimelate decarboxylase signature 165 174 3.1E-27 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CDC59_RS02435 6194facfd1d5d6f8fed3922d5290bad1 419 PRINTS PR01181 Diaminopimelate decarboxylase signature 382 404 3.1E-27 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CDC59_RS02435 6194facfd1d5d6f8fed3922d5290bad1 419 PRINTS PR01181 Diaminopimelate decarboxylase signature 76 93 3.1E-27 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CDC59_RS02435 6194facfd1d5d6f8fed3922d5290bad1 419 PRINTS PR01181 Diaminopimelate decarboxylase signature 302 320 3.1E-27 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CDC59_RS02435 6194facfd1d5d6f8fed3922d5290bad1 419 Gene3D G3DSA:2.40.37.10 273 418 1.4E-39 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CDC59_RS02435 6194facfd1d5d6f8fed3922d5290bad1 419 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 39 283 2.6E-69 T 29-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 CDC59_RS02435 6194facfd1d5d6f8fed3922d5290bad1 419 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 16 415 41.95 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CDC59_RS02435 6194facfd1d5d6f8fed3922d5290bad1 419 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 78 90 3.7E-25 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CDC59_RS02435 6194facfd1d5d6f8fed3922d5290bad1 419 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 191 204 3.7E-25 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CDC59_RS02435 6194facfd1d5d6f8fed3922d5290bad1 419 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 274 293 3.7E-25 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CDC59_RS02435 6194facfd1d5d6f8fed3922d5290bad1 419 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 58 76 3.7E-25 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CDC59_RS02435 6194facfd1d5d6f8fed3922d5290bad1 419 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 372 385 3.7E-25 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CDC59_RS02435 6194facfd1d5d6f8fed3922d5290bad1 419 SUPERFAMILY SSF51419 27 286 2.36E-82 T 29-03-2018 IPR029066 PLP-binding barrel CDC59_RS02435 6194facfd1d5d6f8fed3922d5290bad1 419 SUPERFAMILY SSF50621 263 416 1.84E-53 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CDC59_RS02435 6194facfd1d5d6f8fed3922d5290bad1 419 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 7 414 1.6E-161 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CDC59_RS02435 6194facfd1d5d6f8fed3922d5290bad1 419 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 31 372 2.3E-26 T 29-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 CDC59_RS02435 6194facfd1d5d6f8fed3922d5290bad1 419 Gene3D G3DSA:3.20.20.10 35 272 1.3E-68 T 29-03-2018 IPR029066 PLP-binding barrel CDC59_RS18180 28f000e90c9978181c6d9b5d243589c7 505 Pfam PF00990 Diguanylate cyclase, GGDEF domain 330 491 1.1E-47 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS18180 28f000e90c9978181c6d9b5d243589c7 505 SUPERFAMILY SSF55073 335 494 4.97E-45 T 29-03-2018 IPR029787 Nucleotide cyclase CDC59_RS18180 28f000e90c9978181c6d9b5d243589c7 505 Gene3D G3DSA:3.30.70.270 320 496 5.6E-53 T 29-03-2018 CDC59_RS18180 28f000e90c9978181c6d9b5d243589c7 505 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 326 494 4.1E-48 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS18180 28f000e90c9978181c6d9b5d243589c7 505 SMART SM00267 319 496 5.1E-62 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS18180 28f000e90c9978181c6d9b5d243589c7 505 Gene3D G3DSA:3.30.450.20 42 175 7.0E-13 T 29-03-2018 CDC59_RS18180 28f000e90c9978181c6d9b5d243589c7 505 Pfam PF02743 Cache domain 102 274 1.0E-14 T 29-03-2018 IPR033479 Double Cache domain 1 CDC59_RS18180 28f000e90c9978181c6d9b5d243589c7 505 Gene3D G3DSA:3.30.450.20 176 292 8.0E-11 T 29-03-2018 CDC59_RS21850 2715f5c23dfb1e5d3b7ff27c49b62de8 208 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 4 205 4.1E-74 T 29-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 CDC59_RS21850 2715f5c23dfb1e5d3b7ff27c49b62de8 208 ProSitePatterns PS00159 KDPG and KHG aldolases active site. 35 44 - T 29-03-2018 IPR031337 KDPG/KHG aldolase, active site 1 KEGG: 00030+4.1.2.14|KEGG: 00330+4.1.3.16|KEGG: 00630+4.1.3.16|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 CDC59_RS21850 2715f5c23dfb1e5d3b7ff27c49b62de8 208 Gene3D G3DSA:3.20.20.70 1 208 9.0E-28 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS21850 2715f5c23dfb1e5d3b7ff27c49b62de8 208 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 124 137 - T 29-03-2018 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 CDC59_RS21850 2715f5c23dfb1e5d3b7ff27c49b62de8 208 SUPERFAMILY SSF51569 5 205 4.21E-63 T 29-03-2018 CDC59_RS21850 2715f5c23dfb1e5d3b7ff27c49b62de8 208 Pfam PF01081 KDPG and KHG aldolase 3 199 1.3E-69 T 29-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 CDC59_RS01870 916bf94fc36bf8cc313325fec55254e3 298 PIRSF PIRSF007580 1 275 8.6E-64 T 29-03-2018 IPR016516 Uncharacterised conserved protein UCP07580 CDC59_RS01870 916bf94fc36bf8cc313325fec55254e3 298 Gene3D G3DSA:1.20.1260.10 24 200 1.1E-4 T 29-03-2018 IPR012347 Ferritin-related CDC59_RS01870 916bf94fc36bf8cc313325fec55254e3 298 Pfam PF10118 Predicted metal-dependent hydrolase 5 256 7.7E-76 T 29-03-2018 IPR016516 Uncharacterised conserved protein UCP07580 CDC59_RS21090 880c913032f10f1cb2713df096a7d21c 299 SMART SM00460 184 254 1.4E-20 T 29-03-2018 IPR002931 Transglutaminase-like CDC59_RS21090 880c913032f10f1cb2713df096a7d21c 299 SUPERFAMILY SSF54001 105 295 3.08E-44 T 29-03-2018 CDC59_RS21090 880c913032f10f1cb2713df096a7d21c 299 Pfam PF01841 Transglutaminase-like superfamily 157 252 2.7E-20 T 29-03-2018 IPR002931 Transglutaminase-like CDC59_RS21090 880c913032f10f1cb2713df096a7d21c 299 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 10 89 1.5E-21 T 29-03-2018 IPR013589 Bacterial transglutaminase-like, N-terminal CDC59_RS21090 880c913032f10f1cb2713df096a7d21c 299 Gene3D G3DSA:3.90.260.10 177 259 2.3E-8 T 29-03-2018 IPR002931 Transglutaminase-like CDC59_RS19225 2c2c527be661e233ddcfa1855951b390 274 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 257 1.1E-55 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CDC59_RS19225 2c2c527be661e233ddcfa1855951b390 274 Gene3D G3DSA:1.10.12.10 200 261 4.7E-17 T 29-03-2018 IPR014748 Crontonase, C-terminal CDC59_RS19225 2c2c527be661e233ddcfa1855951b390 274 SUPERFAMILY SSF52096 9 257 6.59E-77 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CDC59_RS19225 2c2c527be661e233ddcfa1855951b390 274 Gene3D G3DSA:3.90.226.10 2 198 1.4E-60 T 29-03-2018 CDC59_RS19225 2c2c527be661e233ddcfa1855951b390 274 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 98 118 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CDC59_RS11595 5e6287b9d84e664563b74a296b7d5539 322 SUPERFAMILY SSF53850 90 297 7.5E-40 T 29-03-2018 CDC59_RS11595 5e6287b9d84e664563b74a296b7d5539 322 Gene3D G3DSA:3.40.190.10 89 176 2.7E-17 T 29-03-2018 CDC59_RS11595 5e6287b9d84e664563b74a296b7d5539 322 Pfam PF03466 LysR substrate binding domain 89 293 2.3E-38 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS11595 5e6287b9d84e664563b74a296b7d5539 322 Gene3D G3DSA:1.10.10.10 1 84 3.4E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS11595 5e6287b9d84e664563b74a296b7d5539 322 SUPERFAMILY SSF46785 2 112 2.45E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS11595 5e6287b9d84e664563b74a296b7d5539 322 Gene3D G3DSA:3.40.190.10 177 264 6.1E-20 T 29-03-2018 CDC59_RS11595 5e6287b9d84e664563b74a296b7d5539 322 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 1.0E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS15375 072ef018469e3090e665516a49934715 130 Gene3D G3DSA:3.30.1130.10 2 130 3.4E-30 T 29-03-2018 CDC59_RS15375 072ef018469e3090e665516a49934715 130 Pfam PF02152 Dihydroneopterin aldolase 16 125 3.0E-23 T 29-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CDC59_RS15375 072ef018469e3090e665516a49934715 130 SUPERFAMILY SSF55620 13 127 1.0E-27 T 29-03-2018 CDC59_RS15375 072ef018469e3090e665516a49934715 130 SMART SM00905 16 127 7.4E-28 T 29-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CDC59_RS15375 072ef018469e3090e665516a49934715 130 TIGRFAM TIGR00526 folB_dom: FolB domain 15 127 2.4E-12 T 29-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CDC59_RS14855 85115f0105c79b775af2fb8f296595a4 210 SUPERFAMILY SSF52172 1 133 5.12E-37 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS14855 85115f0105c79b775af2fb8f296595a4 210 ProSitePatterns PS00622 LuxR-type HTH domain signature. 163 190 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS14855 85115f0105c79b775af2fb8f296595a4 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 5.3E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS14855 85115f0105c79b775af2fb8f296595a4 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 5.3E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS14855 85115f0105c79b775af2fb8f296595a4 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 5.3E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS14855 85115f0105c79b775af2fb8f296595a4 210 SMART SM00421 146 203 5.1E-20 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS14855 85115f0105c79b775af2fb8f296595a4 210 Gene3D G3DSA:3.40.50.2300 1 126 1.2E-37 T 29-03-2018 CDC59_RS14855 85115f0105c79b775af2fb8f296595a4 210 SUPERFAMILY SSF46894 140 209 6.46E-19 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CDC59_RS14855 85115f0105c79b775af2fb8f296595a4 210 Gene3D G3DSA:1.10.10.10 127 210 6.4E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS14855 85115f0105c79b775af2fb8f296595a4 210 SMART SM00448 2 115 4.6E-35 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS14855 85115f0105c79b775af2fb8f296595a4 210 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 203 4.6E-16 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS14855 85115f0105c79b775af2fb8f296595a4 210 Pfam PF00072 Response regulator receiver domain 4 116 1.7E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS19370 40b99a4d68ea4a27ac54eee93e5ddf54 344 Gene3D G3DSA:1.20.970.10 1 70 1.1E-20 T 29-03-2018 CDC59_RS19370 40b99a4d68ea4a27ac54eee93e5ddf54 344 Pfam PF00591 Glycosyl transferase family, a/b domain 76 325 1.3E-93 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CDC59_RS19370 40b99a4d68ea4a27ac54eee93e5ddf54 344 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 6 334 36.844 T 29-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 CDC59_RS19370 40b99a4d68ea4a27ac54eee93e5ddf54 344 Pfam PF02885 Glycosyl transferase family, helical bundle domain 7 66 1.6E-15 T 29-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CDC59_RS19370 40b99a4d68ea4a27ac54eee93e5ddf54 344 Gene3D G3DSA:3.40.1030.10 71 342 1.5E-103 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CDC59_RS19370 40b99a4d68ea4a27ac54eee93e5ddf54 344 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 9 333 6.3E-116 T 29-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 CDC59_RS19370 40b99a4d68ea4a27ac54eee93e5ddf54 344 SUPERFAMILY SSF47648 5 70 7.72E-18 T 29-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CDC59_RS19370 40b99a4d68ea4a27ac54eee93e5ddf54 344 SUPERFAMILY SSF52418 76 336 6.15E-94 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CDC59_RS05015 6cbc0887d936dc135c4e41a83ff5282b 580 Gene3D G3DSA:1.10.1160.10 287 364 4.4E-33 T 29-03-2018 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 CDC59_RS05015 6cbc0887d936dc135c4e41a83ff5282b 580 Gene3D G3DSA:3.40.50.620 40 59 0.19 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDC59_RS05015 6cbc0887d936dc135c4e41a83ff5282b 580 Gene3D G3DSA:2.40.240.10 490 576 8.7E-34 T 29-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CDC59_RS05015 6cbc0887d936dc135c4e41a83ff5282b 580 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 366 557 6.5E-56 T 29-03-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CDC59_RS05015 6cbc0887d936dc135c4e41a83ff5282b 580 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 51 62 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDC59_RS05015 6cbc0887d936dc135c4e41a83ff5282b 580 TIGRFAM TIGR00440 glnS: glutamine--tRNA ligase 46 580 4.6E-224 T 29-03-2018 IPR004514 Glutamine-tRNA synthetase GO:0000166|GO:0004819|GO:0005524|GO:0005737|GO:0006425 KEGG: 00970+6.1.1.18|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CDC59_RS05015 6cbc0887d936dc135c4e41a83ff5282b 580 Hamap MF_00126 Glutamine--tRNA ligase [glnS]. 6 578 52.959 T 29-03-2018 IPR022861 Glutamine-tRNA ligase, bacterial GO:0004819 KEGG: 00970+6.1.1.18 CDC59_RS05015 6cbc0887d936dc135c4e41a83ff5282b 580 PRINTS PR00987 Glutamyl-tRNA synthetase signature 77 90 4.2E-8 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CDC59_RS05015 6cbc0887d936dc135c4e41a83ff5282b 580 PRINTS PR00987 Glutamyl-tRNA synthetase signature 48 60 4.2E-8 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CDC59_RS05015 6cbc0887d936dc135c4e41a83ff5282b 580 PRINTS PR00987 Glutamyl-tRNA synthetase signature 231 241 4.2E-8 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CDC59_RS05015 6cbc0887d936dc135c4e41a83ff5282b 580 SUPERFAMILY SSF52374 45 371 1.53E-95 T 29-03-2018 CDC59_RS05015 6cbc0887d936dc135c4e41a83ff5282b 580 Gene3D G3DSA:3.40.50.620 175 286 1.7E-20 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDC59_RS05015 6cbc0887d936dc135c4e41a83ff5282b 580 Gene3D G3DSA:3.40.50.620 60 174 1.8E-34 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDC59_RS05015 6cbc0887d936dc135c4e41a83ff5282b 580 SUPERFAMILY SSF50715 366 577 1.36E-73 T 29-03-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CDC59_RS05015 6cbc0887d936dc135c4e41a83ff5282b 580 Gene3D G3DSA:2.40.240.10 374 489 4.0E-44 T 29-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CDC59_RS05015 6cbc0887d936dc135c4e41a83ff5282b 580 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 45 363 3.0E-105 T 29-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 CDC59_RS14355 a710bec6326103533112489af27df004 216 SUPERFAMILY SSF47616 83 212 8.49E-34 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like CDC59_RS14355 a710bec6326103533112489af27df004 216 Pfam PF02798 Glutathione S-transferase, N-terminal domain 1 75 2.3E-18 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CDC59_RS14355 a710bec6326103533112489af27df004 216 SUPERFAMILY SSF52833 2 85 3.09E-26 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS14355 a710bec6326103533112489af27df004 216 TIGRFAM TIGR01262 maiA: maleylacetoacetate isomerase 4 213 1.0E-84 T 29-03-2018 IPR005955 Glutathione S-transferases, class Zeta GO:0003824|GO:0005737|GO:0009072 Reactome: R-HSA-156590|Reactome: R-HSA-71182 CDC59_RS14355 a710bec6326103533112489af27df004 216 Gene3D G3DSA:3.40.30.10 1 91 1.6E-29 T 29-03-2018 CDC59_RS14355 a710bec6326103533112489af27df004 216 Pfam PF00043 Glutathione S-transferase, C-terminal domain 140 200 1.7E-7 T 29-03-2018 IPR004046 Glutathione S-transferase, C-terminal CDC59_RS14355 a710bec6326103533112489af27df004 216 Gene3D G3DSA:1.20.1050.10 92 216 2.5E-27 T 29-03-2018 CDC59_RS10740 cb013427ea9af75f03115422103ab1cb 212 Gene3D G3DSA:3.40.1080.10 3 212 9.6E-71 T 29-03-2018 CDC59_RS10740 cb013427ea9af75f03115422103ab1cb 212 SMART SM00882 6 206 1.6E-84 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CDC59_RS10740 cb013427ea9af75f03115422103ab1cb 212 Pfam PF01144 Coenzyme A transferase 7 205 2.5E-41 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CDC59_RS10740 cb013427ea9af75f03115422103ab1cb 212 ProSitePatterns PS01274 Coenzyme A transferases signature 2. 44 52 - T 29-03-2018 IPR004164 Coenzyme A transferase active site GO:0008152|GO:0008410 Reactome: R-HSA-77108 CDC59_RS10740 cb013427ea9af75f03115422103ab1cb 212 SUPERFAMILY SSF100950 3 210 1.4E-73 T 29-03-2018 CDC59_RS10740 cb013427ea9af75f03115422103ab1cb 212 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 3 211 1.4E-97 T 29-03-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 CDC59_RS01215 48b2a92f3d6e440a8ee7c7d4c3c943a7 573 Gene3D G3DSA:3.90.780.10 387 567 1.0E-26 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CDC59_RS01215 48b2a92f3d6e440a8ee7c7d4c3c943a7 573 TIGRFAM TIGR04486 thiosulf_SoxB: thiosulfohydrolase SoxB 2 562 1.1E-254 T 29-03-2018 IPR030998 Thiosulfohydrolase SoxB CDC59_RS01215 48b2a92f3d6e440a8ee7c7d4c3c943a7 573 PRINTS PR01607 Apyrase family signature 263 280 1.7E-11 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CDC59_RS01215 48b2a92f3d6e440a8ee7c7d4c3c943a7 573 PRINTS PR01607 Apyrase family signature 38 56 1.7E-11 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CDC59_RS01215 48b2a92f3d6e440a8ee7c7d4c3c943a7 573 PRINTS PR01607 Apyrase family signature 282 305 1.7E-11 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CDC59_RS01215 48b2a92f3d6e440a8ee7c7d4c3c943a7 573 PRINTS PR01607 Apyrase family signature 314 334 1.7E-11 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CDC59_RS01215 48b2a92f3d6e440a8ee7c7d4c3c943a7 573 SUPERFAMILY SSF56300 111 375 6.65E-78 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CDC59_RS01215 48b2a92f3d6e440a8ee7c7d4c3c943a7 573 SUPERFAMILY SSF56300 36 57 6.65E-78 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CDC59_RS01215 48b2a92f3d6e440a8ee7c7d4c3c943a7 573 Pfam PF02872 5'-nucleotidase, C-terminal domain 394 519 7.8E-15 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CDC59_RS01215 48b2a92f3d6e440a8ee7c7d4c3c943a7 573 Gene3D G3DSA:3.60.21.10 36 386 1.1E-73 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CDC59_RS01215 48b2a92f3d6e440a8ee7c7d4c3c943a7 573 SUPERFAMILY SSF55816 374 561 2.09E-30 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CDC59_RS19325 2e463602e9291d1d55482d360a4ce341 978 Gene3D G3DSA:3.80.10.10 261 390 3.1E-11 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like CDC59_RS19325 2e463602e9291d1d55482d360a4ce341 978 SMART SM00368 623 646 1.9 T 29-03-2018 CDC59_RS19325 2e463602e9291d1d55482d360a4ce341 978 SMART SM00368 767 796 0.59 T 29-03-2018 CDC59_RS19325 2e463602e9291d1d55482d360a4ce341 978 SMART SM00368 647 676 6.3 T 29-03-2018 CDC59_RS19325 2e463602e9291d1d55482d360a4ce341 978 SMART SM00368 290 319 0.63 T 29-03-2018 CDC59_RS19325 2e463602e9291d1d55482d360a4ce341 978 SMART SM00368 911 934 1.1 T 29-03-2018 CDC59_RS19325 2e463602e9291d1d55482d360a4ce341 978 SMART SM00368 200 229 0.91 T 29-03-2018 CDC59_RS19325 2e463602e9291d1d55482d360a4ce341 978 SMART SM00368 815 838 20.0 T 29-03-2018 CDC59_RS19325 2e463602e9291d1d55482d360a4ce341 978 SMART SM00368 176 199 31.0 T 29-03-2018 CDC59_RS19325 2e463602e9291d1d55482d360a4ce341 978 SMART SM00368 863 890 4.2 T 29-03-2018 CDC59_RS19325 2e463602e9291d1d55482d360a4ce341 978 SMART SM00368 695 724 3.8 T 29-03-2018 CDC59_RS19325 2e463602e9291d1d55482d360a4ce341 978 SMART SM00368 839 862 26.0 T 29-03-2018 CDC59_RS19325 2e463602e9291d1d55482d360a4ce341 978 SMART SM00368 105 131 33.0 T 29-03-2018 CDC59_RS19325 2e463602e9291d1d55482d360a4ce341 978 SMART SM00368 935 962 53.0 T 29-03-2018 CDC59_RS19325 2e463602e9291d1d55482d360a4ce341 978 Gene3D G3DSA:3.80.10.10 489 701 8.1E-34 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like CDC59_RS19325 2e463602e9291d1d55482d360a4ce341 978 SMART SM00367 623 647 63.0 T 29-03-2018 IPR006553 Leucine-rich repeat, cysteine-containing subtype CDC59_RS19325 2e463602e9291d1d55482d360a4ce341 978 SMART SM00367 863 887 400.0 T 29-03-2018 IPR006553 Leucine-rich repeat, cysteine-containing subtype CDC59_RS19325 2e463602e9291d1d55482d360a4ce341 978 SMART SM00367 224 248 240.0 T 29-03-2018 IPR006553 Leucine-rich repeat, cysteine-containing subtype CDC59_RS19325 2e463602e9291d1d55482d360a4ce341 978 SMART SM00367 573 600 60.0 T 29-03-2018 IPR006553 Leucine-rich repeat, cysteine-containing subtype CDC59_RS19325 2e463602e9291d1d55482d360a4ce341 978 SMART SM00367 743 767 27.0 T 29-03-2018 IPR006553 Leucine-rich repeat, cysteine-containing subtype CDC59_RS19325 2e463602e9291d1d55482d360a4ce341 978 SMART SM00367 338 363 9.5 T 29-03-2018 IPR006553 Leucine-rich repeat, cysteine-containing subtype CDC59_RS19325 2e463602e9291d1d55482d360a4ce341 978 SMART SM00367 671 695 150.0 T 29-03-2018 IPR006553 Leucine-rich repeat, cysteine-containing subtype CDC59_RS19325 2e463602e9291d1d55482d360a4ce341 978 Gene3D G3DSA:3.40.50.2000 897 963 1.2E-12 T 29-03-2018 CDC59_RS19325 2e463602e9291d1d55482d360a4ce341 978 Gene3D G3DSA:3.40.50.2000 751 812 1.0E-10 T 29-03-2018 CDC59_RS19325 2e463602e9291d1d55482d360a4ce341 978 Gene3D G3DSA:3.40.50.2000 813 896 6.4E-15 T 29-03-2018 CDC59_RS19325 2e463602e9291d1d55482d360a4ce341 978 Gene3D G3DSA:3.40.50.2000 702 750 2.3E-10 T 29-03-2018 CDC59_RS19325 2e463602e9291d1d55482d360a4ce341 978 Gene3D G3DSA:3.40.50.2000 169 260 2.0E-14 T 29-03-2018 CDC59_RS19325 2e463602e9291d1d55482d360a4ce341 978 Gene3D G3DSA:3.80.10.10 81 168 3.2E-6 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like CDC59_RS19325 2e463602e9291d1d55482d360a4ce341 978 Pfam PF13516 Leucine Rich repeat 911 933 1.8E-6 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS19325 2e463602e9291d1d55482d360a4ce341 978 Pfam PF13516 Leucine Rich repeat 815 836 0.12 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS19325 2e463602e9291d1d55482d360a4ce341 978 Pfam PF13516 Leucine Rich repeat 839 861 0.094 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS19325 2e463602e9291d1d55482d360a4ce341 978 Pfam PF13516 Leucine Rich repeat 767 788 0.0062 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS19325 2e463602e9291d1d55482d360a4ce341 978 Pfam PF13516 Leucine Rich repeat 868 885 0.12 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS19325 2e463602e9291d1d55482d360a4ce341 978 Pfam PF13516 Leucine Rich repeat 289 312 2.9E-4 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS19325 2e463602e9291d1d55482d360a4ce341 978 Pfam PF13516 Leucine Rich repeat 694 716 0.25 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS19325 2e463602e9291d1d55482d360a4ce341 978 Pfam PF13516 Leucine Rich repeat 647 669 2.5E-4 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS19325 2e463602e9291d1d55482d360a4ce341 978 Pfam PF13516 Leucine Rich repeat 888 909 0.37 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS19325 2e463602e9291d1d55482d360a4ce341 978 Pfam PF13516 Leucine Rich repeat 155 174 0.25 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS19325 2e463602e9291d1d55482d360a4ce341 978 Pfam PF13516 Leucine Rich repeat 744 765 0.0017 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS19325 2e463602e9291d1d55482d360a4ce341 978 Pfam PF13516 Leucine Rich repeat 201 222 2.5E-5 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS19325 2e463602e9291d1d55482d360a4ce341 978 Pfam PF13516 Leucine Rich repeat 623 644 1.6E-5 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS19325 2e463602e9291d1d55482d360a4ce341 978 Pfam PF13516 Leucine Rich repeat 338 361 0.22 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS19325 2e463602e9291d1d55482d360a4ce341 978 Pfam PF13516 Leucine Rich repeat 314 336 1.4 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS19325 2e463602e9291d1d55482d360a4ce341 978 SUPERFAMILY SSF52047 277 394 1.7E-17 T 29-03-2018 CDC59_RS19325 2e463602e9291d1d55482d360a4ce341 978 SUPERFAMILY SSF52047 548 785 5.49E-46 T 29-03-2018 CDC59_RS19325 2e463602e9291d1d55482d360a4ce341 978 SUPERFAMILY SSF52047 739 962 3.61E-43 T 29-03-2018 CDC59_RS19325 2e463602e9291d1d55482d360a4ce341 978 SUPERFAMILY SSF52047 100 258 1.84E-23 T 29-03-2018 CDC59_RS13795 7261ac6fb8e9d25aecad66ed1dcf0be6 142 Gene3D G3DSA:3.90.1180.10 1 142 4.9E-59 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CDC59_RS13795 7261ac6fb8e9d25aecad66ed1dcf0be6 142 PIRSF PIRSF002181 1 142 2.6E-47 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CDC59_RS13795 7261ac6fb8e9d25aecad66ed1dcf0be6 142 SUPERFAMILY SSF52161 1 140 1.1E-58 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CDC59_RS13795 7261ac6fb8e9d25aecad66ed1dcf0be6 142 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 5 141 6.6E-62 T 29-03-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS13795 7261ac6fb8e9d25aecad66ed1dcf0be6 142 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 141 26.745 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CDC59_RS13795 7261ac6fb8e9d25aecad66ed1dcf0be6 142 Pfam PF00572 Ribosomal protein L13 14 138 1.1E-53 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CDC59_RS14760 54430b42979155f49fc0d0ab13e635e6 166 SUPERFAMILY SSF52374 31 161 1.13E-21 T 29-03-2018 CDC59_RS14760 54430b42979155f49fc0d0ab13e635e6 166 Pfam PF01467 Cytidylyltransferase-like 35 139 7.6E-15 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CDC59_RS14760 54430b42979155f49fc0d0ab13e635e6 166 TIGRFAM TIGR02199 rfaE_dom_II: bifunctional protein RfaE, domain II 22 163 3.9E-59 T 29-03-2018 IPR011914 RfaE bifunctional protein, domain II GO:0005975|GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167 CDC59_RS14760 54430b42979155f49fc0d0ab13e635e6 166 Gene3D G3DSA:3.40.50.620 30 151 5.5E-19 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDC59_RS14760 54430b42979155f49fc0d0ab13e635e6 166 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 33 96 4.1E-12 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CDC59_RS04865 238b4cb734648eb8ba551582f6efa6ea 417 TIGRFAM TIGR01814 kynureninase: kynureninase 9 401 1.2E-119 T 29-03-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 CDC59_RS04865 238b4cb734648eb8ba551582f6efa6ea 417 Pfam PF00266 Aminotransferase class-V 73 324 6.0E-17 T 29-03-2018 IPR000192 Aminotransferase class V domain CDC59_RS04865 238b4cb734648eb8ba551582f6efa6ea 417 SUPERFAMILY SSF53383 5 401 6.4E-89 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS04865 238b4cb734648eb8ba551582f6efa6ea 417 Gene3D G3DSA:3.90.1150.10 294 417 3.7E-23 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS04865 238b4cb734648eb8ba551582f6efa6ea 417 PIRSF PIRSF038800 1 408 7.8E-142 T 29-03-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 CDC59_RS04865 238b4cb734648eb8ba551582f6efa6ea 417 Gene3D G3DSA:3.40.640.10 42 293 1.1E-47 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDC59_RS04865 238b4cb734648eb8ba551582f6efa6ea 417 Hamap MF_01970 Kynureninase [kynU]. 2 400 34.879 T 29-03-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 CDC59_RS12565 864bd69e0ef482715c38bf944be96169 224 Gene3D G3DSA:1.10.150.20 25 87 3.0E-6 T 29-03-2018 CDC59_RS12565 864bd69e0ef482715c38bf944be96169 224 Gene3D G3DSA:3.40.140.10 99 224 8.6E-44 T 29-03-2018 CDC59_RS12565 864bd69e0ef482715c38bf944be96169 224 Pfam PF04002 RadC-like JAB domain 104 222 2.5E-42 T 29-03-2018 IPR025657 RadC-like JAB domain CDC59_RS12565 864bd69e0ef482715c38bf944be96169 224 SUPERFAMILY SSF47781 17 88 1.24E-12 T 29-03-2018 IPR010994 RuvA domain 2-like CDC59_RS12565 864bd69e0ef482715c38bf944be96169 224 TIGRFAM TIGR00608 radc: DNA repair protein RadC 11 223 2.2E-71 T 29-03-2018 IPR001405 RadC protein CDC59_RS17245 a0eb29e44837339a85220469862069fc 1113 SUPERFAMILY SSF56801 26 594 1.03E-83 T 29-03-2018 CDC59_RS17245 a0eb29e44837339a85220469862069fc 1113 Gene3D G3DSA:3.40.50.720 747 1073 2.7E-28 T 29-03-2018 CDC59_RS17245 a0eb29e44837339a85220469862069fc 1113 TIGRFAM TIGR01746 Thioester-redct: thioester reductase domain 749 1098 3.0E-67 T 29-03-2018 IPR010080 Thioester reductase-like domain CDC59_RS17245 a0eb29e44837339a85220469862069fc 1113 Pfam PF07993 Male sterility protein 751 984 3.5E-53 T 29-03-2018 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 CDC59_RS17245 a0eb29e44837339a85220469862069fc 1113 ProSitePatterns PS00455 Putative AMP-binding domain signature. 201 212 - T 29-03-2018 IPR020845 AMP-binding, conserved site CDC59_RS17245 a0eb29e44837339a85220469862069fc 1113 SUPERFAMILY SSF51735 749 1039 1.95E-34 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS17245 a0eb29e44837339a85220469862069fc 1113 Gene3D G3DSA:3.40.50.980 207 366 1.2E-28 T 29-03-2018 CDC59_RS17245 a0eb29e44837339a85220469862069fc 1113 Pfam PF00501 AMP-binding enzyme 37 494 4.3E-68 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CDC59_RS17245 a0eb29e44837339a85220469862069fc 1113 Gene3D G3DSA:3.30.300.30 487 588 6.1E-6 T 29-03-2018 CDC59_RS17245 a0eb29e44837339a85220469862069fc 1113 Gene3D G3DSA:2.30.38.10 382 486 3.3E-9 T 29-03-2018 CDC59_RS17245 a0eb29e44837339a85220469862069fc 1113 Gene3D G3DSA:3.40.50.980 29 206 1.9E-31 T 29-03-2018 CDC59_RS22125 4c50fa4dbc1a0fad5ab022320481a0e4 310 Pfam PF03466 LysR substrate binding domain 91 293 1.2E-37 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS22125 4c50fa4dbc1a0fad5ab022320481a0e4 310 SUPERFAMILY SSF46785 7 114 2.12E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS22125 4c50fa4dbc1a0fad5ab022320481a0e4 310 Gene3D G3DSA:3.40.190.10 92 180 3.9E-21 T 29-03-2018 CDC59_RS22125 4c50fa4dbc1a0fad5ab022320481a0e4 310 Gene3D G3DSA:1.10.10.10 6 87 3.2E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS22125 4c50fa4dbc1a0fad5ab022320481a0e4 310 Gene3D G3DSA:3.40.190.10 181 272 3.1E-21 T 29-03-2018 CDC59_RS22125 4c50fa4dbc1a0fad5ab022320481a0e4 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 4.3E-22 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS22125 4c50fa4dbc1a0fad5ab022320481a0e4 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 1.3E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS22125 4c50fa4dbc1a0fad5ab022320481a0e4 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 1.3E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS22125 4c50fa4dbc1a0fad5ab022320481a0e4 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 1.3E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS22125 4c50fa4dbc1a0fad5ab022320481a0e4 310 SUPERFAMILY SSF53850 92 293 2.35E-34 T 29-03-2018 CDC59_RS16910 b0c1dbf542e3e7809bacceddbf85389b 576 Hamap MF_00572 2-isopropylmalate synthase [leuA]. 6 553 55.046 T 29-03-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CDC59_RS16910 b0c1dbf542e3e7809bacceddbf85389b 576 SMART SM00917 420 552 5.3E-24 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CDC59_RS16910 b0c1dbf542e3e7809bacceddbf85389b 576 Gene3D G3DSA:3.20.20.70 8 374 4.2E-115 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS16910 b0c1dbf542e3e7809bacceddbf85389b 576 SUPERFAMILY SSF51569 20 328 8.24E-106 T 29-03-2018 CDC59_RS16910 b0c1dbf542e3e7809bacceddbf85389b 576 Pfam PF00682 HMGL-like 31 309 2.8E-79 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CDC59_RS16910 b0c1dbf542e3e7809bacceddbf85389b 576 TIGRFAM TIGR00970 leuA_yeast: 2-isopropylmalate synthase 5 552 7.4E-247 T 29-03-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CDC59_RS16910 b0c1dbf542e3e7809bacceddbf85389b 576 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 241 254 - T 29-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CDC59_RS16910 b0c1dbf542e3e7809bacceddbf85389b 576 SUPERFAMILY SSF89000 386 436 1.02E-14 T 29-03-2018 CDC59_RS16910 b0c1dbf542e3e7809bacceddbf85389b 576 Pfam PF08502 LeuA allosteric (dimerisation) domain 421 551 1.5E-24 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CDC59_RS16910 b0c1dbf542e3e7809bacceddbf85389b 576 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 38 54 - T 29-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CDC59_RS16910 b0c1dbf542e3e7809bacceddbf85389b 576 SUPERFAMILY SSF110921 444 551 1.07E-28 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CDC59_RS03240 3f9129cb8017ca7e785e99a31ba3a792 322 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 203 215 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site CDC59_RS03240 3f9129cb8017ca7e785e99a31ba3a792 322 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 81 95 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site CDC59_RS03240 3f9129cb8017ca7e785e99a31ba3a792 322 SUPERFAMILY SSF48576 8 321 3.84E-99 T 29-03-2018 IPR008949 Isoprenoid synthase domain CDC59_RS03240 3f9129cb8017ca7e785e99a31ba3a792 322 Gene3D G3DSA:1.10.600.10 2 322 6.2E-104 T 29-03-2018 IPR008949 Isoprenoid synthase domain CDC59_RS03240 3f9129cb8017ca7e785e99a31ba3a792 322 Pfam PF00348 Polyprenyl synthetase 31 263 1.7E-78 T 29-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 CDC59_RS00240 614fc961ade50394965fe69418a78ac0 192 Gene3D G3DSA:1.10.10.60 153 190 3.2E-16 T 29-03-2018 CDC59_RS00240 614fc961ade50394965fe69418a78ac0 192 SMART SM00448 5 127 3.3E-11 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS00240 614fc961ade50394965fe69418a78ac0 192 Pfam PF00072 Response regulator receiver domain 8 127 1.8E-12 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS00240 614fc961ade50394965fe69418a78ac0 192 Gene3D G3DSA:3.40.50.2300 1 152 1.1E-22 T 29-03-2018 CDC59_RS00240 614fc961ade50394965fe69418a78ac0 192 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 154 171 3.0E-5 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CDC59_RS00240 614fc961ade50394965fe69418a78ac0 192 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 171 191 3.0E-5 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CDC59_RS00240 614fc961ade50394965fe69418a78ac0 192 Pfam PF02954 Bacterial regulatory protein, Fis family 148 187 1.0E-11 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CDC59_RS00240 614fc961ade50394965fe69418a78ac0 192 SUPERFAMILY SSF52172 7 176 1.08E-23 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS06880 7715a22ad41807ec776f1e996faba36d 394 Pfam PF13356 Arm DNA-binding domain 3 87 6.4E-19 T 29-03-2018 IPR025166 Integrase, DNA-binding domain CDC59_RS06880 7715a22ad41807ec776f1e996faba36d 394 SUPERFAMILY SSF56349 99 379 1.68E-54 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CDC59_RS06880 7715a22ad41807ec776f1e996faba36d 394 Gene3D G3DSA:1.10.150.130 88 203 2.0E-18 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal CDC59_RS06880 7715a22ad41807ec776f1e996faba36d 394 Pfam PF00589 Phage integrase family 207 369 3.0E-19 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CDC59_RS06880 7715a22ad41807ec776f1e996faba36d 394 Gene3D G3DSA:1.10.443.10 204 386 1.2E-20 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CDC59_RS10165 10d86f38d2665172eba137bdeb414920 90 SUPERFAMILY SSF47729 1 90 1.4E-30 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CDC59_RS10165 10d86f38d2665172eba137bdeb414920 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 7.6E-17 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CDC59_RS10165 10d86f38d2665172eba137bdeb414920 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 7.6E-17 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CDC59_RS10165 10d86f38d2665172eba137bdeb414920 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 7.6E-17 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CDC59_RS10165 10d86f38d2665172eba137bdeb414920 90 Pfam PF00216 Bacterial DNA-binding protein 1 90 3.2E-31 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CDC59_RS10165 10d86f38d2665172eba137bdeb414920 90 SMART SM00411 1 90 1.4E-33 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CDC59_RS10165 10d86f38d2665172eba137bdeb414920 90 Gene3D G3DSA:4.10.520.10 1 90 3.9E-33 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CDC59_RS10165 10d86f38d2665172eba137bdeb414920 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 29-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 CDC59_RS06085 6f96c18ff24287b6304632019eb342d9 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 120 138 6.3E-11 T 29-03-2018 CDC59_RS06085 6f96c18ff24287b6304632019eb342d9 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 178 196 6.3E-11 T 29-03-2018 CDC59_RS06085 6f96c18ff24287b6304632019eb342d9 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 13 32 6.3E-11 T 29-03-2018 CDC59_RS06085 6f96c18ff24287b6304632019eb342d9 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 301 323 6.3E-11 T 29-03-2018 CDC59_RS06085 6f96c18ff24287b6304632019eb342d9 441 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 12 345 2.6E-55 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS06085 6f96c18ff24287b6304632019eb342d9 441 Gene3D G3DSA:3.50.50.60 173 368 8.2E-31 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS06085 6f96c18ff24287b6304632019eb342d9 441 SUPERFAMILY SSF51905 11 352 6.17E-29 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS06085 6f96c18ff24287b6304632019eb342d9 441 Gene3D G3DSA:3.50.50.60 11 168 1.4E-17 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS06085 6f96c18ff24287b6304632019eb342d9 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 316 323 3.2E-7 T 29-03-2018 CDC59_RS06085 6f96c18ff24287b6304632019eb342d9 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 178 203 3.2E-7 T 29-03-2018 CDC59_RS06085 6f96c18ff24287b6304632019eb342d9 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 12 34 3.2E-7 T 29-03-2018 CDC59_RS01935 2edbd8c2dc94d14402152e3a61c349ac 425 Pfam PF07690 Major Facilitator Superfamily 42 260 4.3E-26 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDC59_RS01935 2edbd8c2dc94d14402152e3a61c349ac 425 Gene3D G3DSA:1.20.1250.20 229 425 3.3E-19 T 29-03-2018 CDC59_RS01935 2edbd8c2dc94d14402152e3a61c349ac 425 Gene3D G3DSA:1.20.1250.20 21 225 2.0E-33 T 29-03-2018 CDC59_RS01935 2edbd8c2dc94d14402152e3a61c349ac 425 SUPERFAMILY SSF103473 23 416 5.75E-62 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS02675 135c2a864afe64312ee5c03d8e11eedd 403 SUPERFAMILY SSF50156 249 373 5.52E-25 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CDC59_RS02675 135c2a864afe64312ee5c03d8e11eedd 403 Gene3D G3DSA:2.40.10.10 53 162 1.0E-33 T 29-03-2018 CDC59_RS02675 135c2a864afe64312ee5c03d8e11eedd 403 PRINTS PR00834 HtrA/DegQ protease family signature 222 239 1.3E-56 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CDC59_RS02675 135c2a864afe64312ee5c03d8e11eedd 403 PRINTS PR00834 HtrA/DegQ protease family signature 147 167 1.3E-56 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CDC59_RS02675 135c2a864afe64312ee5c03d8e11eedd 403 PRINTS PR00834 HtrA/DegQ protease family signature 187 211 1.3E-56 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CDC59_RS02675 135c2a864afe64312ee5c03d8e11eedd 403 PRINTS PR00834 HtrA/DegQ protease family signature 244 261 1.3E-56 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CDC59_RS02675 135c2a864afe64312ee5c03d8e11eedd 403 PRINTS PR00834 HtrA/DegQ protease family signature 126 138 1.3E-56 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CDC59_RS02675 135c2a864afe64312ee5c03d8e11eedd 403 PRINTS PR00834 HtrA/DegQ protease family signature 330 342 1.3E-56 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CDC59_RS02675 135c2a864afe64312ee5c03d8e11eedd 403 SMART SM00228 290 372 1.4E-13 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CDC59_RS02675 135c2a864afe64312ee5c03d8e11eedd 403 Pfam PF13365 Trypsin-like peptidase domain 117 251 2.2E-35 T 29-03-2018 CDC59_RS02675 135c2a864afe64312ee5c03d8e11eedd 403 Pfam PF13180 PDZ domain 290 379 1.2E-17 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CDC59_RS02675 135c2a864afe64312ee5c03d8e11eedd 403 SUPERFAMILY SSF50494 60 286 3.14E-66 T 29-03-2018 IPR009003 Peptidase S1, PA clan CDC59_RS02675 135c2a864afe64312ee5c03d8e11eedd 403 Gene3D G3DSA:2.40.10.10 163 280 6.1E-41 T 29-03-2018 CDC59_RS02675 135c2a864afe64312ee5c03d8e11eedd 403 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 62 384 6.8E-133 T 29-03-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 CDC59_RS02675 135c2a864afe64312ee5c03d8e11eedd 403 Gene3D G3DSA:2.30.42.10 285 390 4.6E-26 T 29-03-2018 CDC59_RS09565 5daf1b41735b1e81033dc6db231ae2cd 306 Pfam PF00775 Dioxygenase 101 287 1.2E-61 T 29-03-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 CDC59_RS09565 5daf1b41735b1e81033dc6db231ae2cd 306 Gene3D G3DSA:2.60.130.10 1 306 3.8E-68 T 29-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CDC59_RS09565 5daf1b41735b1e81033dc6db231ae2cd 306 TIGRFAM TIGR02439 catechol_proteo: catechol 1,2-dioxygenase 4 287 1.5E-136 T 29-03-2018 IPR012801 Catechol 1,2-dioxygenase, proteobacteria GO:0005506|GO:0018576|GO:0019614|GO:0055114 KEGG: 00361+1.13.11.1|KEGG: 00362+1.13.11.1|KEGG: 00364+1.13.11.1|KEGG: 00623+1.13.11.1 CDC59_RS09565 5daf1b41735b1e81033dc6db231ae2cd 306 ProSitePatterns PS00083 Intradiol ring-cleavage dioxygenases signature. 133 161 - T 29-03-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 CDC59_RS09565 5daf1b41735b1e81033dc6db231ae2cd 306 SUPERFAMILY SSF49482 14 295 9.94E-90 T 29-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CDC59_RS09565 5daf1b41735b1e81033dc6db231ae2cd 306 Pfam PF04444 Catechol dioxygenase N terminus 23 91 1.2E-19 T 29-03-2018 IPR007535 Catechol dioxygenase, N-terminal GO:0005506|GO:0009712|GO:0018576|GO:0055114 CDC59_RS23030 2f95b0c24cb7d1d65d6aae9402f13102 519 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 121 517 1.6E-156 T 29-03-2018 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 CDC59_RS23030 2f95b0c24cb7d1d65d6aae9402f13102 519 SMART SM00858 23 94 3.4E-18 T 29-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 CDC59_RS23030 2f95b0c24cb7d1d65d6aae9402f13102 519 Pfam PF08666 SAF domain 23 94 1.5E-12 T 29-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 CDC59_RS05480 d38408a1e8228ed5fee7f35270497ea3 435 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 14 430 1.6E-135 T 29-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CDC59_RS05480 d38408a1e8228ed5fee7f35270497ea3 435 Gene3D G3DSA:3.65.10.10 21 229 8.8E-60 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CDC59_RS05480 d38408a1e8228ed5fee7f35270497ea3 435 ProSitePatterns PS00885 EPSP synthase signature 2. 346 364 - T 29-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CDC59_RS05480 d38408a1e8228ed5fee7f35270497ea3 435 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 10 435 32.84 T 29-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CDC59_RS05480 d38408a1e8228ed5fee7f35270497ea3 435 ProSitePatterns PS00104 EPSP synthase signature 1. 89 103 - T 29-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CDC59_RS05480 d38408a1e8228ed5fee7f35270497ea3 435 SUPERFAMILY SSF55205 1 431 4.45E-126 T 29-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CDC59_RS05480 d38408a1e8228ed5fee7f35270497ea3 435 Gene3D G3DSA:3.65.10.10 230 435 3.7E-65 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CDC59_RS05480 d38408a1e8228ed5fee7f35270497ea3 435 PIRSF PIRSF000505 5 435 1.5E-139 T 29-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CDC59_RS05480 d38408a1e8228ed5fee7f35270497ea3 435 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 10 428 2.1E-127 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CDC59_RS21875 c3e3e83e4774b3d298e91eda616933b9 428 Pfam PF00672 HAMP domain 166 211 6.2E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CDC59_RS21875 c3e3e83e4774b3d298e91eda616933b9 428 Gene3D G3DSA:3.30.565.10 259 424 1.8E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS21875 c3e3e83e4774b3d298e91eda616933b9 428 SUPERFAMILY SSF47384 200 272 1.08E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS21875 c3e3e83e4774b3d298e91eda616933b9 428 SUPERFAMILY SSF55874 284 423 6.94E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS21875 c3e3e83e4774b3d298e91eda616933b9 428 PRINTS PR00344 Bacterial sensor protein C-terminal signature 365 375 3.3E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS21875 c3e3e83e4774b3d298e91eda616933b9 428 PRINTS PR00344 Bacterial sensor protein C-terminal signature 347 361 3.3E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS21875 c3e3e83e4774b3d298e91eda616933b9 428 PRINTS PR00344 Bacterial sensor protein C-terminal signature 381 399 3.3E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS21875 c3e3e83e4774b3d298e91eda616933b9 428 Pfam PF00512 His Kinase A (phospho-acceptor) domain 218 272 7.1E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS21875 c3e3e83e4774b3d298e91eda616933b9 428 Gene3D G3DSA:1.10.287.130 207 258 1.1E-11 T 29-03-2018 CDC59_RS21875 c3e3e83e4774b3d298e91eda616933b9 428 Gene3D G3DSA:1.10.3720.10 2 182 0.0013 T 29-03-2018 CDC59_RS21875 c3e3e83e4774b3d298e91eda616933b9 428 SMART SM00304 164 216 8.6E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CDC59_RS21875 c3e3e83e4774b3d298e91eda616933b9 428 SMART SM00387 312 425 5.1E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS21875 c3e3e83e4774b3d298e91eda616933b9 428 SMART SM00388 217 275 3.4E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS21875 c3e3e83e4774b3d298e91eda616933b9 428 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 314 423 1.4E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS06580 bb9257f580ced15e6f1c88f7cdb1e103 153 Pfam PF07045 Domain of unknown function (DUF1330) 57 150 5.4E-26 T 29-03-2018 IPR010753 Domain of unknown function DUF1330 CDC59_RS06580 bb9257f580ced15e6f1c88f7cdb1e103 153 Gene3D G3DSA:3.30.70.100 53 152 3.3E-24 T 29-03-2018 CDC59_RS06580 bb9257f580ced15e6f1c88f7cdb1e103 153 SUPERFAMILY SSF54909 57 150 2.25E-21 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CDC59_RS17170 8cc44588ffb9bbff6ae40a5537f8a3c6 110 Hamap MF_00724 Flagellar hook-basal body complex protein FliE [fliE]. 1 110 19.572 T 29-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CDC59_RS17170 8cc44588ffb9bbff6ae40a5537f8a3c6 110 TIGRFAM TIGR00205 fliE: flagellar hook-basal body complex protein FliE 31 110 1.0E-23 T 29-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CDC59_RS17170 8cc44588ffb9bbff6ae40a5537f8a3c6 110 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 74 90 1.0E-14 T 29-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CDC59_RS17170 8cc44588ffb9bbff6ae40a5537f8a3c6 110 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 39 55 1.0E-14 T 29-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CDC59_RS17170 8cc44588ffb9bbff6ae40a5537f8a3c6 110 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 95 108 1.0E-14 T 29-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CDC59_RS17170 8cc44588ffb9bbff6ae40a5537f8a3c6 110 Pfam PF02049 Flagellar hook-basal body complex protein FliE 31 110 5.5E-30 T 29-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CDC59_RS09415 2e77c54b573b97d027f3b4463b0c0978 540 Pfam PF00005 ABC transporter 18 184 8.4E-19 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS09415 2e77c54b573b97d027f3b4463b0c0978 540 Pfam PF00005 ABC transporter 335 475 9.9E-18 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS09415 2e77c54b573b97d027f3b4463b0c0978 540 Pfam PF12848 ABC transporter 224 309 6.5E-22 T 29-03-2018 IPR032781 ABC-transporter extension domain CDC59_RS09415 2e77c54b573b97d027f3b4463b0c0978 540 SUPERFAMILY SSF52540 296 535 2.34E-35 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS09415 2e77c54b573b97d027f3b4463b0c0978 540 Gene3D G3DSA:3.40.50.300 287 539 7.3E-41 T 29-03-2018 CDC59_RS09415 2e77c54b573b97d027f3b4463b0c0978 540 SMART SM00382 26 238 7.2E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS09415 2e77c54b573b97d027f3b4463b0c0978 540 SMART SM00382 343 519 1.7E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS09415 2e77c54b573b97d027f3b4463b0c0978 540 Gene3D G3DSA:3.40.50.300 1 286 1.3E-48 T 29-03-2018 CDC59_RS09415 2e77c54b573b97d027f3b4463b0c0978 540 SUPERFAMILY SSF52540 6 237 1.88E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS07745 75a3af730f00665c862a53cfb425ab93 286 SUPERFAMILY SSF89550 10 90 1.41E-50 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CDC59_RS07745 75a3af730f00665c862a53cfb425ab93 286 SUPERFAMILY SSF89550 173 284 1.41E-50 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CDC59_RS07745 75a3af730f00665c862a53cfb425ab93 286 SMART SM00481 12 77 6.0E-14 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CDC59_RS07745 75a3af730f00665c862a53cfb425ab93 286 Gene3D G3DSA:3.20.20.140 9 270 4.5E-43 T 29-03-2018 CDC59_RS07745 75a3af730f00665c862a53cfb425ab93 286 Pfam PF02811 PHP domain 13 102 1.1E-6 T 29-03-2018 IPR004013 PHP domain GO:0003824 CDC59_RS01260 9b9c8f616fd5a732975a8dde5e14c89b 700 Pfam PF13432 Tetratricopeptide repeat 326 381 5.7E-5 T 29-03-2018 CDC59_RS01260 9b9c8f616fd5a732975a8dde5e14c89b 700 Pfam PF13432 Tetratricopeptide repeat 17 80 0.0012 T 29-03-2018 CDC59_RS01260 9b9c8f616fd5a732975a8dde5e14c89b 700 Pfam PF07719 Tetratricopeptide repeat 183 215 3.8E-6 T 29-03-2018 IPR013105 Tetratricopeptide repeat 2 CDC59_RS01260 9b9c8f616fd5a732975a8dde5e14c89b 700 Gene3D G3DSA:1.25.40.10 61 123 8.8E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS01260 9b9c8f616fd5a732975a8dde5e14c89b 700 SMART SM00028 13 46 67.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CDC59_RS01260 9b9c8f616fd5a732975a8dde5e14c89b 700 SMART SM00028 81 114 0.016 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CDC59_RS01260 9b9c8f616fd5a732975a8dde5e14c89b 700 SMART SM00028 217 250 43.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CDC59_RS01260 9b9c8f616fd5a732975a8dde5e14c89b 700 SMART SM00028 183 216 9.7E-5 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CDC59_RS01260 9b9c8f616fd5a732975a8dde5e14c89b 700 SMART SM00028 251 284 1.2 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CDC59_RS01260 9b9c8f616fd5a732975a8dde5e14c89b 700 SMART SM00028 47 80 46.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CDC59_RS01260 9b9c8f616fd5a732975a8dde5e14c89b 700 SMART SM00028 320 353 0.036 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CDC59_RS01260 9b9c8f616fd5a732975a8dde5e14c89b 700 SMART SM00028 149 182 2.2E-6 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CDC59_RS01260 9b9c8f616fd5a732975a8dde5e14c89b 700 SMART SM00028 115 148 0.0011 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CDC59_RS01260 9b9c8f616fd5a732975a8dde5e14c89b 700 SMART SM00028 392 425 170.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CDC59_RS01260 9b9c8f616fd5a732975a8dde5e14c89b 700 SMART SM00028 285 318 0.58 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CDC59_RS01260 9b9c8f616fd5a732975a8dde5e14c89b 700 Gene3D G3DSA:1.10.287.1110 201 214 1.1E-5 T 29-03-2018 CDC59_RS01260 9b9c8f616fd5a732975a8dde5e14c89b 700 SUPERFAMILY SSF48452 17 107 5.84E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS01260 9b9c8f616fd5a732975a8dde5e14c89b 700 Pfam PF13469 Sulfotransferase family 462 649 1.0E-43 T 29-03-2018 CDC59_RS01260 9b9c8f616fd5a732975a8dde5e14c89b 700 Pfam PF13374 Tetratricopeptide repeat 85 110 7.8E-4 T 29-03-2018 CDC59_RS01260 9b9c8f616fd5a732975a8dde5e14c89b 700 SUPERFAMILY SSF48452 87 311 1.64E-42 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS01260 9b9c8f616fd5a732975a8dde5e14c89b 700 Gene3D G3DSA:1.25.40.10 318 428 1.4E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS01260 9b9c8f616fd5a732975a8dde5e14c89b 700 Gene3D G3DSA:1.25.40.10 215 264 1.9E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS01260 9b9c8f616fd5a732975a8dde5e14c89b 700 SUPERFAMILY SSF48452 321 417 2.06E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS01260 9b9c8f616fd5a732975a8dde5e14c89b 700 Gene3D G3DSA:1.25.40.10 160 200 5.5E-18 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS01260 9b9c8f616fd5a732975a8dde5e14c89b 700 Gene3D G3DSA:1.25.40.10 265 315 4.2E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS01260 9b9c8f616fd5a732975a8dde5e14c89b 700 Gene3D G3DSA:3.40.50.300 460 687 1.3E-41 T 29-03-2018 CDC59_RS01260 9b9c8f616fd5a732975a8dde5e14c89b 700 SUPERFAMILY SSF52540 461 697 1.71E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS01260 9b9c8f616fd5a732975a8dde5e14c89b 700 Gene3D G3DSA:1.25.20.10 5 60 3.2E-6 T 29-03-2018 CDC59_RS01260 9b9c8f616fd5a732975a8dde5e14c89b 700 Pfam PF13424 Tetratricopeptide repeat 252 313 3.3E-8 T 29-03-2018 CDC59_RS01260 9b9c8f616fd5a732975a8dde5e14c89b 700 Pfam PF13424 Tetratricopeptide repeat 118 180 1.0E-10 T 29-03-2018 CDC59_RS01260 9b9c8f616fd5a732975a8dde5e14c89b 700 Gene3D G3DSA:1.25.40.10 124 159 4.5E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS05635 8138ba80b16c6b72697227117a6baacf 438 Gene3D G3DSA:1.10.287.40 2 104 2.4E-26 T 29-03-2018 CDC59_RS05635 8138ba80b16c6b72697227117a6baacf 438 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 433 39.703 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CDC59_RS05635 8138ba80b16c6b72697227117a6baacf 438 Gene3D G3DSA:3.30.930.10 105 438 1.3E-90 T 29-03-2018 CDC59_RS05635 8138ba80b16c6b72697227117a6baacf 438 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 235 411 7.8E-35 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDC59_RS05635 8138ba80b16c6b72697227117a6baacf 438 SUPERFAMILY SSF46589 1 112 2.56E-31 T 29-03-2018 IPR010978 tRNA-binding arm GO:0000166 CDC59_RS05635 8138ba80b16c6b72697227117a6baacf 438 PRINTS PR00981 Seryl-tRNA synthetase signature 288 301 1.1E-32 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CDC59_RS05635 8138ba80b16c6b72697227117a6baacf 438 PRINTS PR00981 Seryl-tRNA synthetase signature 363 379 1.1E-32 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CDC59_RS05635 8138ba80b16c6b72697227117a6baacf 438 PRINTS PR00981 Seryl-tRNA synthetase signature 276 288 1.1E-32 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CDC59_RS05635 8138ba80b16c6b72697227117a6baacf 438 PRINTS PR00981 Seryl-tRNA synthetase signature 328 341 1.1E-32 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CDC59_RS05635 8138ba80b16c6b72697227117a6baacf 438 PRINTS PR00981 Seryl-tRNA synthetase signature 345 361 1.1E-32 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CDC59_RS05635 8138ba80b16c6b72697227117a6baacf 438 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 107 1.2E-32 T 29-03-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 CDC59_RS05635 8138ba80b16c6b72697227117a6baacf 438 SUPERFAMILY SSF55681 116 430 2.66E-101 T 29-03-2018 CDC59_RS05635 8138ba80b16c6b72697227117a6baacf 438 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 428 4.6E-162 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CDC59_RS05635 8138ba80b16c6b72697227117a6baacf 438 PIRSF PIRSF001529 1 437 1.7E-175 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CDC59_RS18615 ce54fe00ed744032f6a303d05f13711b 319 Pfam PF02274 Amidinotransferase 25 315 1.9E-67 T 29-03-2018 CDC59_RS18615 ce54fe00ed744032f6a303d05f13711b 319 PIRSF PIRSF028188 1 319 3.2E-139 T 29-03-2018 IPR014541 Predicted amidinotransferase, FN0238 type CDC59_RS18615 ce54fe00ed744032f6a303d05f13711b 319 SUPERFAMILY SSF55909 21 315 3.64E-40 T 29-03-2018 CDC59_RS18615 ce54fe00ed744032f6a303d05f13711b 319 Gene3D G3DSA:3.75.10.10 16 315 9.8E-42 T 29-03-2018 CDC59_RS05125 7e0134518a319ef14a0c92682a5adcbb 416 PRINTS PR00407 Eukaryotic molybdopterin domain signature 338 350 4.5E-13 T 29-03-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 CDC59_RS05125 7e0134518a319ef14a0c92682a5adcbb 416 PRINTS PR00407 Eukaryotic molybdopterin domain signature 84 100 4.5E-13 T 29-03-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 CDC59_RS05125 7e0134518a319ef14a0c92682a5adcbb 416 PRINTS PR00407 Eukaryotic molybdopterin domain signature 218 234 4.5E-13 T 29-03-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 CDC59_RS05125 7e0134518a319ef14a0c92682a5adcbb 416 PRINTS PR00407 Eukaryotic molybdopterin domain signature 163 178 4.5E-13 T 29-03-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 CDC59_RS05125 7e0134518a319ef14a0c92682a5adcbb 416 PRINTS PR00407 Eukaryotic molybdopterin domain signature 299 311 4.5E-13 T 29-03-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 CDC59_RS05125 7e0134518a319ef14a0c92682a5adcbb 416 PRINTS PR00407 Eukaryotic molybdopterin domain signature 235 248 4.5E-13 T 29-03-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 CDC59_RS05125 7e0134518a319ef14a0c92682a5adcbb 416 SUPERFAMILY SSF56524 61 332 7.85E-74 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CDC59_RS05125 7e0134518a319ef14a0c92682a5adcbb 416 SUPERFAMILY SSF81296 302 414 1.4E-28 T 29-03-2018 IPR014756 Immunoglobulin E-set CDC59_RS05125 7e0134518a319ef14a0c92682a5adcbb 416 Pfam PF03404 Mo-co oxidoreductase dimerisation domain 299 407 1.1E-8 T 29-03-2018 IPR005066 Moybdenum cofactor oxidoreductase, dimerisation GO:0016491|GO:0030151|GO:0055114 Reactome: R-HSA-1614517 CDC59_RS05125 7e0134518a319ef14a0c92682a5adcbb 416 Gene3D G3DSA:2.60.40.650 301 416 1.1E-26 T 29-03-2018 CDC59_RS05125 7e0134518a319ef14a0c92682a5adcbb 416 Pfam PF00174 Oxidoreductase molybdopterin binding domain 100 272 1.6E-49 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CDC59_RS05125 7e0134518a319ef14a0c92682a5adcbb 416 Gene3D G3DSA:3.90.420.10 40 300 3.3E-64 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CDC59_RS07900 69834f4a47d145c1a2968e308aa13d2d 475 SUPERFAMILY SSF56037 368 464 9.68E-23 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CDC59_RS07900 69834f4a47d145c1a2968e308aa13d2d 475 Gene3D G3DSA:3.40.50.620 31 221 6.4E-38 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDC59_RS07900 69834f4a47d145c1a2968e308aa13d2d 475 Pfam PF09179 TilS substrate binding domain 266 333 7.8E-17 T 29-03-2018 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CDC59_RS07900 69834f4a47d145c1a2968e308aa13d2d 475 Pfam PF11734 TilS substrate C-terminal domain 392 463 1.1E-21 T 29-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CDC59_RS07900 69834f4a47d145c1a2968e308aa13d2d 475 SMART SM00977 392 463 1.7E-22 T 29-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CDC59_RS07900 69834f4a47d145c1a2968e308aa13d2d 475 SUPERFAMILY SSF52402 37 251 2.56E-53 T 29-03-2018 CDC59_RS07900 69834f4a47d145c1a2968e308aa13d2d 475 Pfam PF01171 PP-loop family 39 218 7.2E-54 T 29-03-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 CDC59_RS07900 69834f4a47d145c1a2968e308aa13d2d 475 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 39 218 1.3E-48 T 29-03-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CDC59_RS07900 69834f4a47d145c1a2968e308aa13d2d 475 SUPERFAMILY SSF82829 252 334 5.89E-19 T 29-03-2018 CDC59_RS07900 69834f4a47d145c1a2968e308aa13d2d 475 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 17 325 21.82 T 29-03-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CDC59_RS07900 69834f4a47d145c1a2968e308aa13d2d 475 TIGRFAM TIGR02433 lysidine_TilS_C: tRNA(Ile)-lysidine synthetase, C-terminal domain 392 438 4.3E-14 T 29-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CDC59_RS07550 74800bea39745f7bd3d99ea15c0217d1 113 Pfam PF01381 Helix-turn-helix 28 82 6.6E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDC59_RS07550 74800bea39745f7bd3d99ea15c0217d1 113 SMART SM00530 27 82 1.7E-12 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDC59_RS07550 74800bea39745f7bd3d99ea15c0217d1 113 Gene3D G3DSA:1.10.260.40 20 84 7.3E-17 T 29-03-2018 CDC59_RS07550 74800bea39745f7bd3d99ea15c0217d1 113 SUPERFAMILY SSF47413 20 86 3.94E-16 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDC59_RS11840 38b65548064041a713dbf2b90c9f138f 720 SMART SM00316 620 690 1.2E-22 T 29-03-2018 IPR022967 RNA-binding domain, S1 CDC59_RS11840 38b65548064041a713dbf2b90c9f138f 720 Pfam PF03725 3' exoribonuclease family, domain 2 461 529 4.0E-5 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CDC59_RS11840 38b65548064041a713dbf2b90c9f138f 720 Pfam PF03725 3' exoribonuclease family, domain 2 147 209 2.1E-12 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CDC59_RS11840 38b65548064041a713dbf2b90c9f138f 720 Pfam PF00575 S1 RNA binding domain 619 690 5.8E-15 T 29-03-2018 IPR003029 S1 domain GO:0003676 CDC59_RS11840 38b65548064041a713dbf2b90c9f138f 720 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 3 693 30.101 T 29-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CDC59_RS11840 38b65548064041a713dbf2b90c9f138f 720 Gene3D G3DSA:2.40.50.140 617 696 5.4E-22 T 29-03-2018 CDC59_RS11840 38b65548064041a713dbf2b90c9f138f 720 SUPERFAMILY SSF54211 295 488 1.11E-49 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CDC59_RS11840 38b65548064041a713dbf2b90c9f138f 720 SUPERFAMILY SSF54211 2 144 3.39E-52 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CDC59_RS11840 38b65548064041a713dbf2b90c9f138f 720 Gene3D G3DSA:3.30.230.70 14 226 7.5E-47 T 29-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CDC59_RS11840 38b65548064041a713dbf2b90c9f138f 720 SUPERFAMILY SSF55666 450 548 5.33E-28 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CDC59_RS11840 38b65548064041a713dbf2b90c9f138f 720 Gene3D G3DSA:3.30.1370.10 545 616 1.7E-15 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CDC59_RS11840 38b65548064041a713dbf2b90c9f138f 720 Pfam PF00013 KH domain 557 613 5.2E-11 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CDC59_RS11840 38b65548064041a713dbf2b90c9f138f 720 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 242 320 2.4E-16 T 29-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CDC59_RS11840 38b65548064041a713dbf2b90c9f138f 720 SMART SM00322 552 617 7.6E-14 T 29-03-2018 IPR004087 K Homology domain GO:0003676 CDC59_RS11840 38b65548064041a713dbf2b90c9f138f 720 SUPERFAMILY SSF50249 620 697 2.61E-19 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDC59_RS11840 38b65548064041a713dbf2b90c9f138f 720 SUPERFAMILY SSF46915 239 321 3.4E-16 T 29-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CDC59_RS11840 38b65548064041a713dbf2b90c9f138f 720 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 10 691 0.0 T 29-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CDC59_RS11840 38b65548064041a713dbf2b90c9f138f 720 Gene3D G3DSA:1.10.10.400 238 317 1.2E-16 T 29-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CDC59_RS11840 38b65548064041a713dbf2b90c9f138f 720 Gene3D G3DSA:3.30.230.70 318 544 1.0E-59 T 29-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CDC59_RS11840 38b65548064041a713dbf2b90c9f138f 720 SUPERFAMILY SSF54791 554 640 4.55E-23 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CDC59_RS11840 38b65548064041a713dbf2b90c9f138f 720 SUPERFAMILY SSF55666 145 234 8.27E-29 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CDC59_RS11840 38b65548064041a713dbf2b90c9f138f 720 PIRSF PIRSF005499 1 720 2.1E-296 T 29-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CDC59_RS11840 38b65548064041a713dbf2b90c9f138f 720 Pfam PF01138 3' exoribonuclease family, domain 1 324 456 1.5E-23 T 29-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CDC59_RS11840 38b65548064041a713dbf2b90c9f138f 720 Pfam PF01138 3' exoribonuclease family, domain 1 15 144 5.2E-21 T 29-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CDC59_RS07870 57cdb5d2b260e23dee1d3cb49f2f3a69 168 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 4 166 2.4E-48 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CDC59_RS07870 57cdb5d2b260e23dee1d3cb49f2f3a69 168 PIRSF PIRSF001467 1 168 1.3E-27 T 29-03-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 CDC59_RS07870 57cdb5d2b260e23dee1d3cb49f2f3a69 168 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 38 55 - T 29-03-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 CDC59_RS07870 57cdb5d2b260e23dee1d3cb49f2f3a69 168 SUPERFAMILY SSF50891 4 167 4.38E-59 T 29-03-2018 IPR029000 Cyclophilin-like domain CDC59_RS07870 57cdb5d2b260e23dee1d3cb49f2f3a69 168 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 17 32 8.4E-12 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CDC59_RS07870 57cdb5d2b260e23dee1d3cb49f2f3a69 168 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 43 55 8.4E-12 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CDC59_RS07870 57cdb5d2b260e23dee1d3cb49f2f3a69 168 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 122 137 8.4E-12 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CDC59_RS07870 57cdb5d2b260e23dee1d3cb49f2f3a69 168 Gene3D G3DSA:2.40.100.10 1 168 1.5E-52 T 29-03-2018 IPR029000 Cyclophilin-like domain CDC59_RS21280 e29b5aa471562e78af95ad1d44229a31 850 Pfam PF05524 PEP-utilising enzyme, N-terminal 296 413 2.1E-20 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CDC59_RS21280 e29b5aa471562e78af95ad1d44229a31 850 Pfam PF00391 PEP-utilising enzyme, mobile domain 438 511 2.1E-23 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CDC59_RS21280 e29b5aa471562e78af95ad1d44229a31 850 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 9 129 4.4E-39 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CDC59_RS21280 e29b5aa471562e78af95ad1d44229a31 850 SUPERFAMILY SSF52009 412 530 3.27E-33 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CDC59_RS21280 e29b5aa471562e78af95ad1d44229a31 850 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 72 84 - T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CDC59_RS21280 e29b5aa471562e78af95ad1d44229a31 850 SUPERFAMILY SSF55594 180 261 8.9E-21 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CDC59_RS21280 e29b5aa471562e78af95ad1d44229a31 850 Gene3D G3DSA:1.10.274.10 322 421 1.4E-24 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CDC59_RS21280 e29b5aa471562e78af95ad1d44229a31 850 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 10 129 2.6E-35 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CDC59_RS21280 e29b5aa471562e78af95ad1d44229a31 850 SUPERFAMILY SSF51621 536 829 1.26E-98 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CDC59_RS21280 e29b5aa471562e78af95ad1d44229a31 850 Gene3D G3DSA:3.50.30.10 422 540 7.4E-26 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CDC59_RS21280 e29b5aa471562e78af95ad1d44229a31 850 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 780 792 8.5E-19 T 29-03-2018 CDC59_RS21280 e29b5aa471562e78af95ad1d44229a31 850 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 744 759 8.5E-19 T 29-03-2018 CDC59_RS21280 e29b5aa471562e78af95ad1d44229a31 850 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 579 598 8.5E-19 T 29-03-2018 CDC59_RS21280 e29b5aa471562e78af95ad1d44229a31 850 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 727 742 8.5E-19 T 29-03-2018 CDC59_RS21280 e29b5aa471562e78af95ad1d44229a31 850 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 296 843 1.2E-146 T 29-03-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 CDC59_RS21280 e29b5aa471562e78af95ad1d44229a31 850 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 183 255 3.2E-18 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CDC59_RS21280 e29b5aa471562e78af95ad1d44229a31 850 Pfam PF00381 PTS HPr component phosphorylation site 180 256 1.5E-20 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CDC59_RS21280 e29b5aa471562e78af95ad1d44229a31 850 Gene3D G3DSA:3.30.1340.10 178 259 1.3E-21 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CDC59_RS21280 e29b5aa471562e78af95ad1d44229a31 850 Gene3D G3DSA:2.70.70.10 1 155 2.6E-44 T 29-03-2018 CDC59_RS21280 e29b5aa471562e78af95ad1d44229a31 850 PRINTS PR00107 Phosphocarrier protein signature 187 203 1.9E-8 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CDC59_RS21280 e29b5aa471562e78af95ad1d44229a31 850 PRINTS PR00107 Phosphocarrier protein signature 227 244 1.9E-8 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CDC59_RS21280 e29b5aa471562e78af95ad1d44229a31 850 PRINTS PR00107 Phosphocarrier protein signature 212 227 1.9E-8 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CDC59_RS21280 e29b5aa471562e78af95ad1d44229a31 850 SUPERFAMILY SSF51261 8 151 8.02E-40 T 29-03-2018 IPR011055 Duplicated hybrid motif CDC59_RS21280 e29b5aa471562e78af95ad1d44229a31 850 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 727 745 - T 29-03-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 CDC59_RS21280 e29b5aa471562e78af95ad1d44229a31 850 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 187 194 - T 29-03-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site CDC59_RS21280 e29b5aa471562e78af95ad1d44229a31 850 Gene3D G3DSA:3.20.20.60 541 850 5.3E-96 T 29-03-2018 CDC59_RS21280 e29b5aa471562e78af95ad1d44229a31 850 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 540 820 2.5E-98 T 29-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 CDC59_RS21280 e29b5aa471562e78af95ad1d44229a31 850 SUPERFAMILY SSF47831 322 430 5.75E-23 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CDC59_RS23725 8bc3f3f98c2d04f13ace568321b6a722 267 Gene3D G3DSA:2.60.120.10 6 99 3.9E-5 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CDC59_RS23725 8bc3f3f98c2d04f13ace568321b6a722 267 Pfam PF12833 Helix-turn-helix domain 181 259 2.5E-23 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CDC59_RS23725 8bc3f3f98c2d04f13ace568321b6a722 267 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 210 253 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CDC59_RS23725 8bc3f3f98c2d04f13ace568321b6a722 267 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 241 257 1.6E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CDC59_RS23725 8bc3f3f98c2d04f13ace568321b6a722 267 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 226 241 1.6E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CDC59_RS23725 8bc3f3f98c2d04f13ace568321b6a722 267 SUPERFAMILY SSF46689 157 209 4.57E-6 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS23725 8bc3f3f98c2d04f13ace568321b6a722 267 SMART SM00342 175 257 8.1E-25 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CDC59_RS23725 8bc3f3f98c2d04f13ace568321b6a722 267 SUPERFAMILY SSF46689 211 261 4.3E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS23725 8bc3f3f98c2d04f13ace568321b6a722 267 SUPERFAMILY SSF51182 15 91 8.01E-9 T 29-03-2018 IPR011051 RmlC-like cupin domain CDC59_RS23725 8bc3f3f98c2d04f13ace568321b6a722 267 Gene3D G3DSA:1.10.10.60 211 266 2.0E-13 T 29-03-2018 CDC59_RS23725 8bc3f3f98c2d04f13ace568321b6a722 267 Gene3D G3DSA:1.10.10.60 150 210 2.4E-9 T 29-03-2018 CDC59_RS22605 d14162c601ac18889800fc9ac216b384 562 Gene3D G3DSA:2.30.38.10 354 438 8.9E-19 T 29-03-2018 CDC59_RS22605 d14162c601ac18889800fc9ac216b384 562 Pfam PF00501 AMP-binding enzyme 48 445 2.1E-77 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CDC59_RS22605 d14162c601ac18889800fc9ac216b384 562 Gene3D G3DSA:3.40.50.980 40 205 1.3E-33 T 29-03-2018 CDC59_RS22605 d14162c601ac18889800fc9ac216b384 562 ProSitePatterns PS00455 Putative AMP-binding domain signature. 200 211 - T 29-03-2018 IPR020845 AMP-binding, conserved site CDC59_RS22605 d14162c601ac18889800fc9ac216b384 562 Gene3D G3DSA:3.40.50.980 206 353 1.1E-36 T 29-03-2018 CDC59_RS22605 d14162c601ac18889800fc9ac216b384 562 SUPERFAMILY SSF56801 20 541 3.79E-135 T 29-03-2018 CDC59_RS22605 d14162c601ac18889800fc9ac216b384 562 Pfam PF13193 AMP-binding enzyme C-terminal domain 454 531 3.0E-18 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CDC59_RS22605 d14162c601ac18889800fc9ac216b384 562 Gene3D G3DSA:3.30.300.30 441 557 1.2E-22 T 29-03-2018 CDC59_RS12750 ba96d4a3c1d1a4488013d82cec257cb1 153 SUPERFAMILY SSF141488 70 149 1.7E-18 T 29-03-2018 IPR018660 C-type lysozyme inhibitor CDC59_RS12750 ba96d4a3c1d1a4488013d82cec257cb1 153 Pfam PF09864 Membrane-bound lysozyme-inhibitor of c-type lysozyme 74 135 9.2E-17 T 29-03-2018 IPR018660 C-type lysozyme inhibitor CDC59_RS13465 a2a86b960080f9837130d59cabda3199 104 Pfam PF13937 Domain of unknown function (DUF4212) 15 80 1.2E-19 T 29-03-2018 IPR019886 Sodium symporter small subunit, predicted CDC59_RS13465 a2a86b960080f9837130d59cabda3199 104 TIGRFAM TIGR03647 Na_symport_sm: putative solute:sodium symporter small subunit 15 83 1.8E-25 T 29-03-2018 IPR019886 Sodium symporter small subunit, predicted CDC59_RS15605 07b3796cb2ddc4476c7dc417189eb997 379 Pfam PF01266 FAD dependent oxidoreductase 6 340 2.9E-36 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CDC59_RS15605 07b3796cb2ddc4476c7dc417189eb997 379 Gene3D G3DSA:3.30.9.10 160 309 1.8E-20 T 29-03-2018 CDC59_RS15605 07b3796cb2ddc4476c7dc417189eb997 379 SUPERFAMILY SSF51905 1 282 3.11E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS15605 07b3796cb2ddc4476c7dc417189eb997 379 Gene3D G3DSA:3.40.50.720 1 159 9.4E-6 T 29-03-2018 CDC59_RS00020 f8d3b8373470efa43984d0472aaef20a 563 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 363 551 4.0E-75 T 29-03-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal CDC59_RS00020 f8d3b8373470efa43984d0472aaef20a 563 PRINTS PR00701 60kDa inner membrane protein signature 261 276 3.3E-51 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CDC59_RS00020 f8d3b8373470efa43984d0472aaef20a 563 PRINTS PR00701 60kDa inner membrane protein signature 517 540 3.3E-51 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CDC59_RS00020 f8d3b8373470efa43984d0472aaef20a 563 PRINTS PR00701 60kDa inner membrane protein signature 2 23 3.3E-51 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CDC59_RS00020 f8d3b8373470efa43984d0472aaef20a 563 PRINTS PR00701 60kDa inner membrane protein signature 90 111 3.3E-51 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CDC59_RS00020 f8d3b8373470efa43984d0472aaef20a 563 PRINTS PR00701 60kDa inner membrane protein signature 173 193 3.3E-51 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CDC59_RS00020 f8d3b8373470efa43984d0472aaef20a 563 PRINTS PR00701 60kDa inner membrane protein signature 481 503 3.3E-51 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CDC59_RS00020 f8d3b8373470efa43984d0472aaef20a 563 PRINTS PR00701 60kDa inner membrane protein signature 226 244 3.3E-51 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CDC59_RS00020 f8d3b8373470efa43984d0472aaef20a 563 PRINTS PR00701 60kDa inner membrane protein signature 334 354 3.3E-51 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CDC59_RS00020 f8d3b8373470efa43984d0472aaef20a 563 Pfam PF02096 60Kd inner membrane protein 364 551 7.1E-65 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CDC59_RS00020 f8d3b8373470efa43984d0472aaef20a 563 PRINTS PR01900 YidC translocation/secretion protein signature 506 530 4.1E-25 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CDC59_RS00020 f8d3b8373470efa43984d0472aaef20a 563 PRINTS PR01900 YidC translocation/secretion protein signature 487 502 4.1E-25 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CDC59_RS00020 f8d3b8373470efa43984d0472aaef20a 563 PRINTS PR01900 YidC translocation/secretion protein signature 349 365 4.1E-25 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CDC59_RS00020 f8d3b8373470efa43984d0472aaef20a 563 Hamap MF_01810 Membrane protein insertase YidC [yidC]. 4 553 24.607 T 29-03-2018 IPR019998 Membrane insertase YidC GO:0016021|GO:0051205 CDC59_RS00020 f8d3b8373470efa43984d0472aaef20a 563 TIGRFAM TIGR03593 yidC_nterm: membrane protein insertase, YidC/Oxa1 family, N-terminal domain 4 362 6.1E-110 T 29-03-2018 IPR028053 Membrane insertase YidC, N-terminal CDC59_RS00020 f8d3b8373470efa43984d0472aaef20a 563 Pfam PF14849 YidC periplasmic domain 85 353 1.3E-78 T 29-03-2018 IPR028053 Membrane insertase YidC, N-terminal CDC59_RS19375 3b5b9d78fb10a4ef0a0030eef808d554 733 SUPERFAMILY SSF51905 393 450 9.45E-16 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS19375 3b5b9d78fb10a4ef0a0030eef808d554 733 SUPERFAMILY SSF51905 538 676 9.45E-16 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS19375 3b5b9d78fb10a4ef0a0030eef808d554 733 Gene3D G3DSA:3.20.20.70 10 381 2.4E-80 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS19375 3b5b9d78fb10a4ef0a0030eef808d554 733 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 17 342 2.4E-60 T 29-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CDC59_RS19375 3b5b9d78fb10a4ef0a0030eef808d554 733 Gene3D G3DSA:3.50.50.60 494 637 1.3E-5 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS19375 3b5b9d78fb10a4ef0a0030eef808d554 733 Gene3D G3DSA:3.40.50.720 382 493 2.3E-13 T 29-03-2018 CDC59_RS19375 3b5b9d78fb10a4ef0a0030eef808d554 733 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 395 414 2.5E-6 T 29-03-2018 CDC59_RS19375 3b5b9d78fb10a4ef0a0030eef808d554 733 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 478 496 2.5E-6 T 29-03-2018 CDC59_RS19375 3b5b9d78fb10a4ef0a0030eef808d554 733 SUPERFAMILY SSF51395 12 375 7.94E-81 T 29-03-2018 CDC59_RS19375 3b5b9d78fb10a4ef0a0030eef808d554 733 SUPERFAMILY SSF51971 354 524 3.3E-21 T 29-03-2018 CDC59_RS19375 3b5b9d78fb10a4ef0a0030eef808d554 733 Pfam PF00890 FAD binding domain 395 433 1.4E-4 T 29-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CDC59_RS16755 49dd851dbaae4b1bc6cb14a93e07ee65 333 Pfam PF13994 PgaD-like protein 4 148 3.5E-25 T 29-03-2018 IPR023829 Poly-beta-1,6-N-acetyl-D-glucosamine biosynthesis protein PgaD GO:0042710 CDC59_RS23020 2903e7519683f5ef80412ca4d92c97ce 264 SUPERFAMILY SSF51621 9 258 8.48E-83 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CDC59_RS23020 2903e7519683f5ef80412ca4d92c97ce 264 TIGRFAM TIGR02311 HpaI: 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase 11 258 1.2E-116 T 29-03-2018 IPR012689 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase GO:0010124|GO:0018802 KEGG: 00350+4.1.2.52 CDC59_RS23020 2903e7519683f5ef80412ca4d92c97ce 264 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 23 249 1.7E-58 T 29-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 CDC59_RS23020 2903e7519683f5ef80412ca4d92c97ce 264 Gene3D G3DSA:3.20.20.60 5 258 2.7E-48 T 29-03-2018 CDC59_RS20340 016834fa0cc8e84f06f70e1e41d09df5 957 Gene3D G3DSA:1.10.10.10 892 946 2.1E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS20340 016834fa0cc8e84f06f70e1e41d09df5 957 SUPERFAMILY SSF46785 890 953 2.58E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS20340 016834fa0cc8e84f06f70e1e41d09df5 957 SMART SM00382 611 806 8.0E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS20340 016834fa0cc8e84f06f70e1e41d09df5 957 Pfam PF09397 Ftsk gamma domain 892 952 2.7E-25 T 29-03-2018 IPR018541 FtsK gamma domain CDC59_RS20340 016834fa0cc8e84f06f70e1e41d09df5 957 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 5 114 1.9E-8 T 29-03-2018 IPR025199 DNA translocase FtsK, 4TM region CDC59_RS20340 016834fa0cc8e84f06f70e1e41d09df5 957 SMART SM00843 890 955 7.8E-36 T 29-03-2018 IPR018541 FtsK gamma domain CDC59_RS20340 016834fa0cc8e84f06f70e1e41d09df5 957 SUPERFAMILY SSF52540 563 858 4.38E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS20340 016834fa0cc8e84f06f70e1e41d09df5 957 Pfam PF01580 FtsK/SpoIIIE family 576 785 1.6E-68 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CDC59_RS20340 016834fa0cc8e84f06f70e1e41d09df5 957 Gene3D G3DSA:3.40.50.300 567 825 1.8E-57 T 29-03-2018 CDC59_RS04415 3fcbf51c601b5cc8c8975a479f0f4033 2040 SUPERFAMILY SSF47226 54 166 1.13E-11 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CDC59_RS04415 3fcbf51c601b5cc8c8975a479f0f4033 2040 Gene3D G3DSA:3.30.565.10 1553 1739 2.9E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS04415 3fcbf51c601b5cc8c8975a479f0f4033 2040 SUPERFAMILY SSF47226 1255 1363 5.76E-22 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CDC59_RS04415 3fcbf51c601b5cc8c8975a479f0f4033 2040 SMART SM00073 1058 1155 0.051 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CDC59_RS04415 3fcbf51c601b5cc8c8975a479f0f4033 2040 SMART SM00073 755 862 3.3E-8 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CDC59_RS04415 3fcbf51c601b5cc8c8975a479f0f4033 2040 SMART SM00073 1255 1351 0.015 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CDC59_RS04415 3fcbf51c601b5cc8c8975a479f0f4033 2040 Gene3D G3DSA:1.10.287.560 1429 1552 9.5E-5 T 29-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 CDC59_RS04415 3fcbf51c601b5cc8c8975a479f0f4033 2040 SUPERFAMILY SSF50341 1738 1868 7.59E-25 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CDC59_RS04415 3fcbf51c601b5cc8c8975a479f0f4033 2040 SUPERFAMILY SSF55874 1555 1737 1.14E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS04415 3fcbf51c601b5cc8c8975a479f0f4033 2040 SMART SM00260 1731 1871 2.2E-14 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CDC59_RS04415 3fcbf51c601b5cc8c8975a479f0f4033 2040 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1602 1738 2.3E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS04415 3fcbf51c601b5cc8c8975a479f0f4033 2040 SMART SM01231 1416 1553 1.5E-6 T 29-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 CDC59_RS04415 3fcbf51c601b5cc8c8975a479f0f4033 2040 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1699 1717 1.5E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS04415 3fcbf51c601b5cc8c8975a479f0f4033 2040 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1683 1693 1.5E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS04415 3fcbf51c601b5cc8c8975a479f0f4033 2040 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1723 1736 1.5E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS04415 3fcbf51c601b5cc8c8975a479f0f4033 2040 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1643 1657 1.5E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS04415 3fcbf51c601b5cc8c8975a479f0f4033 2040 Gene3D G3DSA:1.20.120.160 747 914 3.5E-23 T 29-03-2018 CDC59_RS04415 3fcbf51c601b5cc8c8975a479f0f4033 2040 SUPERFAMILY SSF52172 1915 2033 4.55E-33 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS04415 3fcbf51c601b5cc8c8975a479f0f4033 2040 Pfam PF01584 CheW-like domain 1743 1872 1.2E-19 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CDC59_RS04415 3fcbf51c601b5cc8c8975a479f0f4033 2040 Gene3D G3DSA:1.20.120.160 1252 1428 2.6E-21 T 29-03-2018 CDC59_RS04415 3fcbf51c601b5cc8c8975a479f0f4033 2040 Gene3D G3DSA:1.20.120.160 487 622 0.35 T 29-03-2018 CDC59_RS04415 3fcbf51c601b5cc8c8975a479f0f4033 2040 Gene3D G3DSA:1.20.120.160 40 181 2.8E-7 T 29-03-2018 CDC59_RS04415 3fcbf51c601b5cc8c8975a479f0f4033 2040 Gene3D G3DSA:1.20.120.160 1060 1206 3.1E-17 T 29-03-2018 CDC59_RS04415 3fcbf51c601b5cc8c8975a479f0f4033 2040 SMART SM00387 1598 1739 2.7E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS04415 3fcbf51c601b5cc8c8975a479f0f4033 2040 SUPERFAMILY SSF47226 1061 1178 2.49E-17 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CDC59_RS04415 3fcbf51c601b5cc8c8975a479f0f4033 2040 Gene3D G3DSA:2.30.30.40 1808 1870 1.2E-18 T 29-03-2018 CDC59_RS04415 3fcbf51c601b5cc8c8975a479f0f4033 2040 Gene3D G3DSA:2.30.30.40 1740 1777 0.022 T 29-03-2018 CDC59_RS04415 3fcbf51c601b5cc8c8975a479f0f4033 2040 SMART SM00448 1913 2026 2.0E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS04415 3fcbf51c601b5cc8c8975a479f0f4033 2040 Gene3D G3DSA:1.20.120.160 354 428 0.018 T 29-03-2018 CDC59_RS04415 3fcbf51c601b5cc8c8975a479f0f4033 2040 Pfam PF01627 Hpt domain 1062 1152 1.5E-8 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CDC59_RS04415 3fcbf51c601b5cc8c8975a479f0f4033 2040 Pfam PF01627 Hpt domain 1258 1353 1.8E-13 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CDC59_RS04415 3fcbf51c601b5cc8c8975a479f0f4033 2040 Pfam PF01627 Hpt domain 757 858 4.3E-15 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CDC59_RS04415 3fcbf51c601b5cc8c8975a479f0f4033 2040 SUPERFAMILY SSF47226 754 888 1.16E-21 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CDC59_RS04415 3fcbf51c601b5cc8c8975a479f0f4033 2040 Gene3D G3DSA:3.40.50.2300 1909 2039 4.9E-32 T 29-03-2018 CDC59_RS04415 3fcbf51c601b5cc8c8975a479f0f4033 2040 Pfam PF00072 Response regulator receiver domain 1915 2026 2.2E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS21060 742aeb3f5a0e5b2036dfe0d646b18f2b 393 SUPERFAMILY SSF51905 326 388 1.62E-56 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS21060 742aeb3f5a0e5b2036dfe0d646b18f2b 393 SUPERFAMILY SSF51905 16 229 1.62E-56 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS21060 742aeb3f5a0e5b2036dfe0d646b18f2b 393 Pfam PF01266 FAD dependent oxidoreductase 17 365 1.9E-57 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CDC59_RS21060 742aeb3f5a0e5b2036dfe0d646b18f2b 393 Gene3D G3DSA:3.50.50.60 4 393 1.0E-47 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS01650 1dd666d5e5e1b3ed388ca7e6b26dc646 1191 SUPERFAMILY SSF52518 457 647 7.36E-15 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CDC59_RS01650 1dd666d5e5e1b3ed388ca7e6b26dc646 1191 Gene3D G3DSA:3.40.50.970 292 662 8.6E-41 T 29-03-2018 CDC59_RS01650 1dd666d5e5e1b3ed388ca7e6b26dc646 1191 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 477 630 2.1E-6 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CDC59_RS01650 1dd666d5e5e1b3ed388ca7e6b26dc646 1191 SUPERFAMILY SSF53323 746 993 1.44E-33 T 29-03-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CDC59_RS01650 1dd666d5e5e1b3ed388ca7e6b26dc646 1191 Gene3D G3DSA:3.40.50.970 25 291 9.9E-22 T 29-03-2018 CDC59_RS01650 1dd666d5e5e1b3ed388ca7e6b26dc646 1191 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 754 940 2.4E-22 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CDC59_RS01650 1dd666d5e5e1b3ed388ca7e6b26dc646 1191 Gene3D G3DSA:3.40.920.10 744 956 3.3E-49 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CDC59_RS01650 1dd666d5e5e1b3ed388ca7e6b26dc646 1191 SUPERFAMILY SSF52518 29 215 3.47E-20 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CDC59_RS09165 fd05cb695dc4dc80ea8d137a89496730 186 Pfam PF01765 Ribosome recycling factor 21 184 1.0E-63 T 29-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 CDC59_RS09165 fd05cb695dc4dc80ea8d137a89496730 186 Hamap MF_00040 Ribosome-recycling factor [frr]. 4 186 27.49 T 29-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 CDC59_RS09165 fd05cb695dc4dc80ea8d137a89496730 186 TIGRFAM TIGR00496 frr: ribosome recycling factor 11 186 1.5E-69 T 29-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 CDC59_RS09165 fd05cb695dc4dc80ea8d137a89496730 186 SUPERFAMILY SSF55194 6 185 1.83E-71 T 29-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 CDC59_RS09165 fd05cb695dc4dc80ea8d137a89496730 186 Gene3D G3DSA:1.10.132.20 76 185 1.1E-38 T 29-03-2018 CDC59_RS09165 fd05cb695dc4dc80ea8d137a89496730 186 Gene3D G3DSA:1.10.132.20 3 75 7.1E-11 T 29-03-2018 CDC59_RS15410 f0f484b98007c0abc37e76247cd7ce0c 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 96 111 4.4E-17 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS15410 f0f484b98007c0abc37e76247cd7ce0c 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 145 165 4.4E-17 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS15410 f0f484b98007c0abc37e76247cd7ce0c 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 79 95 4.4E-17 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS15410 f0f484b98007c0abc37e76247cd7ce0c 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 115 131 4.4E-17 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS15410 f0f484b98007c0abc37e76247cd7ce0c 170 Pfam PF01047 MarR family 64 118 1.0E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS15410 f0f484b98007c0abc37e76247cd7ce0c 170 Gene3D G3DSA:1.10.10.10 8 170 6.1E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS15410 f0f484b98007c0abc37e76247cd7ce0c 170 SMART SM00347 52 155 3.8E-22 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS15410 f0f484b98007c0abc37e76247cd7ce0c 170 SUPERFAMILY SSF46785 19 167 6.66E-34 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS15410 f0f484b98007c0abc37e76247cd7ce0c 170 ProSitePatterns PS01117 MarR-type HTH domain signature. 94 128 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CDC59_RS05040 7efe4627c34e3e4c5ad14be3fee393ce 880 SUPERFAMILY SSF101353 257 466 4.32E-61 T 29-03-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 CDC59_RS05040 7efe4627c34e3e4c5ad14be3fee393ce 880 SUPERFAMILY SSF55681 2 256 2.73E-103 T 29-03-2018 CDC59_RS05040 7efe4627c34e3e4c5ad14be3fee393ce 880 SUPERFAMILY SSF55186 558 713 8.24E-49 T 29-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 CDC59_RS05040 7efe4627c34e3e4c5ad14be3fee393ce 880 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 880 200.291 T 29-03-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 CDC59_RS05040 7efe4627c34e3e4c5ad14be3fee393ce 880 Gene3D G3DSA:1.20.1170.10 705 843 2.5E-5 T 29-03-2018 CDC59_RS05040 7efe4627c34e3e4c5ad14be3fee393ce 880 Pfam PF02272 DHHA1 domain 739 876 2.1E-28 T 29-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CDC59_RS05040 7efe4627c34e3e4c5ad14be3fee393ce 880 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 659 701 4.5E-18 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CDC59_RS05040 7efe4627c34e3e4c5ad14be3fee393ce 880 SUPERFAMILY SSF50447 459 558 1.65E-17 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CDC59_RS05040 7efe4627c34e3e4c5ad14be3fee393ce 880 Gene3D G3DSA:3.30.930.10 1 253 2.7E-111 T 29-03-2018 CDC59_RS05040 7efe4627c34e3e4c5ad14be3fee393ce 880 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 5 859 6.3E-303 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CDC59_RS05040 7efe4627c34e3e4c5ad14be3fee393ce 880 SMART SM00863 659 701 3.3E-20 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CDC59_RS05040 7efe4627c34e3e4c5ad14be3fee393ce 880 Pfam PF01411 tRNA synthetases class II (A) 5 560 2.9E-212 T 29-03-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 CDC59_RS05040 7efe4627c34e3e4c5ad14be3fee393ce 880 PRINTS PR00980 Alanyl-tRNA synthetase signature 283 299 1.9E-31 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CDC59_RS05040 7efe4627c34e3e4c5ad14be3fee393ce 880 PRINTS PR00980 Alanyl-tRNA synthetase signature 74 85 1.9E-31 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CDC59_RS05040 7efe4627c34e3e4c5ad14be3fee393ce 880 PRINTS PR00980 Alanyl-tRNA synthetase signature 205 216 1.9E-31 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CDC59_RS05040 7efe4627c34e3e4c5ad14be3fee393ce 880 PRINTS PR00980 Alanyl-tRNA synthetase signature 237 250 1.9E-31 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CDC59_RS05040 7efe4627c34e3e4c5ad14be3fee393ce 880 PRINTS PR00980 Alanyl-tRNA synthetase signature 307 320 1.9E-31 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CDC59_RS05040 7efe4627c34e3e4c5ad14be3fee393ce 880 Gene3D G3DSA:3.30.980.10 559 704 2.7E-41 T 29-03-2018 CDC59_RS09445 61b41125680a1ff7620f0d7cc908dfd9 619 Pfam PF00723 Glycosyl hydrolases family 15 241 550 9.9E-62 T 29-03-2018 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: R-HSA-70221 CDC59_RS09445 61b41125680a1ff7620f0d7cc908dfd9 619 Gene3D G3DSA:1.50.10.10 224 567 1.8E-96 T 29-03-2018 CDC59_RS09445 61b41125680a1ff7620f0d7cc908dfd9 619 SUPERFAMILY SSF48208 219 607 1.09E-108 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CDC59_RS05990 6c956bff7c2b679cb6bff3ae208f5166 289 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 277 5.6E-38 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CDC59_RS05990 6c956bff7c2b679cb6bff3ae208f5166 289 Gene3D G3DSA:1.10.3470.10 2 287 1.7E-41 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CDC59_RS14945 f0ec15c5b17d9c502392863ce3d78e38 393 Gene3D G3DSA:3.40.47.10 266 390 3.5E-29 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS14945 f0ec15c5b17d9c502392863ce3d78e38 393 Gene3D G3DSA:3.40.47.10 1 265 3.7E-58 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS14945 f0ec15c5b17d9c502392863ce3d78e38 393 PIRSF PIRSF000429 1 393 1.9E-115 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CDC59_RS14945 f0ec15c5b17d9c502392863ce3d78e38 393 Pfam PF02803 Thiolase, C-terminal domain 272 391 7.2E-40 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CDC59_RS14945 f0ec15c5b17d9c502392863ce3d78e38 393 SUPERFAMILY SSF53901 5 270 2.2E-82 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS14945 f0ec15c5b17d9c502392863ce3d78e38 393 SUPERFAMILY SSF53901 272 392 3.02E-39 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS14945 f0ec15c5b17d9c502392863ce3d78e38 393 ProSitePatterns PS00099 Thiolases active site. 374 387 - T 29-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CDC59_RS14945 f0ec15c5b17d9c502392863ce3d78e38 393 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 390 6.4E-127 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CDC59_RS14945 f0ec15c5b17d9c502392863ce3d78e38 393 Pfam PF00108 Thiolase, N-terminal domain 5 263 2.1E-89 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CDC59_RS06265 6735839a977405a4cb41b28ff2989e52 209 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 3 105 23.093 T 29-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS CDC59_RS06265 6735839a977405a4cb41b28ff2989e52 209 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 8 104 2.7E-33 T 29-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS CDC59_RS06265 6735839a977405a4cb41b28ff2989e52 209 Pfam PF02410 Ribosomal silencing factor during starvation 10 104 1.6E-25 T 29-03-2018 CDC59_RS06265 6735839a977405a4cb41b28ff2989e52 209 Gene3D G3DSA:3.30.460.10 1 117 3.7E-32 T 29-03-2018 CDC59_RS06265 6735839a977405a4cb41b28ff2989e52 209 SUPERFAMILY SSF81301 1 109 5.72E-36 T 29-03-2018 CDC59_RS12515 d609612b28f3b8c161fafa7f699d4af2 349 SUPERFAMILY SSF54292 2 90 5.64E-25 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CDC59_RS12515 d609612b28f3b8c161fafa7f699d4af2 349 Pfam PF00970 Oxidoreductase FAD-binding domain 105 203 1.3E-14 T 29-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CDC59_RS12515 d609612b28f3b8c161fafa7f699d4af2 349 Pfam PF00175 Oxidoreductase NAD-binding domain 215 320 4.3E-21 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CDC59_RS12515 d609612b28f3b8c161fafa7f699d4af2 349 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 6 81 2.5E-15 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CDC59_RS12515 d609612b28f3b8c161fafa7f699d4af2 349 PRINTS PR00410 Phenol hydroxylase reductase family signature 198 207 1.3E-17 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CDC59_RS12515 d609612b28f3b8c161fafa7f699d4af2 349 PRINTS PR00410 Phenol hydroxylase reductase family signature 132 144 1.3E-17 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CDC59_RS12515 d609612b28f3b8c161fafa7f699d4af2 349 PRINTS PR00410 Phenol hydroxylase reductase family signature 306 314 1.3E-17 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CDC59_RS12515 d609612b28f3b8c161fafa7f699d4af2 349 PRINTS PR00410 Phenol hydroxylase reductase family signature 239 248 1.3E-17 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CDC59_RS12515 d609612b28f3b8c161fafa7f699d4af2 349 PRINTS PR00410 Phenol hydroxylase reductase family signature 214 233 1.3E-17 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CDC59_RS12515 d609612b28f3b8c161fafa7f699d4af2 349 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 148 155 9.3E-6 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CDC59_RS12515 d609612b28f3b8c161fafa7f699d4af2 349 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 214 233 9.3E-6 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CDC59_RS12515 d609612b28f3b8c161fafa7f699d4af2 349 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 306 314 9.3E-6 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CDC59_RS12515 d609612b28f3b8c161fafa7f699d4af2 349 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 239 248 9.3E-6 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CDC59_RS12515 d609612b28f3b8c161fafa7f699d4af2 349 SUPERFAMILY SSF52343 207 340 4.71E-38 T 29-03-2018 CDC59_RS12515 d609612b28f3b8c161fafa7f699d4af2 349 Gene3D G3DSA:3.40.50.80 206 342 1.9E-23 T 29-03-2018 CDC59_RS12515 d609612b28f3b8c161fafa7f699d4af2 349 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 37 45 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CDC59_RS12515 d609612b28f3b8c161fafa7f699d4af2 349 SUPERFAMILY SSF63380 102 205 1.49E-21 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CDC59_RS12515 d609612b28f3b8c161fafa7f699d4af2 349 Gene3D G3DSA:3.10.20.30 1 98 4.2E-21 T 29-03-2018 IPR012675 Beta-grasp domain CDC59_RS12515 d609612b28f3b8c161fafa7f699d4af2 349 Gene3D G3DSA:2.40.30.10 99 202 3.7E-21 T 29-03-2018 CDC59_RS23850 cbe4298230b2e76a175edf1e663293ec 454 SUPERFAMILY SSF53335 80 264 2.64E-47 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS23850 cbe4298230b2e76a175edf1e663293ec 454 Pfam PF01739 CheR methyltransferase, SAM binding domain 81 255 1.7E-43 T 29-03-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal CDC59_RS23850 cbe4298230b2e76a175edf1e663293ec 454 SUPERFAMILY SSF48452 358 444 2.74E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS23850 cbe4298230b2e76a175edf1e663293ec 454 Gene3D G3DSA:3.40.50.150 79 269 8.2E-44 T 29-03-2018 CDC59_RS23850 cbe4298230b2e76a175edf1e663293ec 454 PRINTS PR00996 Glutamate methyltransferase family signature 111 131 1.4E-22 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CDC59_RS23850 cbe4298230b2e76a175edf1e663293ec 454 PRINTS PR00996 Glutamate methyltransferase family signature 213 227 1.4E-22 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CDC59_RS23850 cbe4298230b2e76a175edf1e663293ec 454 PRINTS PR00996 Glutamate methyltransferase family signature 144 160 1.4E-22 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CDC59_RS23850 cbe4298230b2e76a175edf1e663293ec 454 PRINTS PR00996 Glutamate methyltransferase family signature 232 255 1.4E-22 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CDC59_RS23850 cbe4298230b2e76a175edf1e663293ec 454 PRINTS PR00996 Glutamate methyltransferase family signature 73 85 1.4E-22 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CDC59_RS23850 cbe4298230b2e76a175edf1e663293ec 454 SMART SM00138 2 271 3.0E-44 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CDC59_RS23850 cbe4298230b2e76a175edf1e663293ec 454 Gene3D G3DSA:1.25.40.10 347 449 5.6E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS01310 cf82fc13605658a6f410b047c9d71df0 122 SUPERFAMILY SSF48371 32 110 4.6E-6 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 CDC59_RS01310 cf82fc13605658a6f410b047c9d71df0 122 Gene3D G3DSA:1.25.40.70 4 109 2.0E-4 T 29-03-2018 CDC59_RS02795 34ba6d0c719c8f9508e806c4c4195cf9 508 Hamap MF_01069 Glucans biosynthesis protein G [mdoG]. 5 507 62.163 T 29-03-2018 IPR023704 Glucan biosynthesis protein G CDC59_RS02795 34ba6d0c719c8f9508e806c4c4195cf9 508 SUPERFAMILY SSF74650 23 392 1.41E-163 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CDC59_RS02795 34ba6d0c719c8f9508e806c4c4195cf9 508 Pfam PF04349 Periplasmic glucan biosynthesis protein, MdoG 23 504 3.9E-201 T 29-03-2018 IPR007444 Glucan biosynthesis, periplasmic, MdoG C-terminal GO:0016051|GO:0042597 CDC59_RS02795 34ba6d0c719c8f9508e806c4c4195cf9 508 SUPERFAMILY SSF81296 396 507 2.52E-29 T 29-03-2018 IPR014756 Immunoglobulin E-set CDC59_RS02795 34ba6d0c719c8f9508e806c4c4195cf9 508 PIRSF PIRSF006281 2 508 3.5E-221 T 29-03-2018 IPR014438 Glucan biosynthesis, periplasmic, MdoG/D CDC59_RS02795 34ba6d0c719c8f9508e806c4c4195cf9 508 Gene3D G3DSA:2.60.40.10 396 508 5.7E-33 T 29-03-2018 IPR013783 Immunoglobulin-like fold CDC59_RS02795 34ba6d0c719c8f9508e806c4c4195cf9 508 Gene3D G3DSA:2.70.98.10 23 392 1.3E-168 T 29-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CDC59_RS06115 d044c870f6055f62819673db385f09bd 94 SUPERFAMILY SSF116842 18 82 3.27E-20 T 29-03-2018 CDC59_RS06115 d044c870f6055f62819673db385f09bd 94 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 22 61 2.0E-15 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CDC59_RS06115 d044c870f6055f62819673db385f09bd 94 PIRSF PIRSF006488 10 94 2.2E-28 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CDC59_RS06115 d044c870f6055f62819673db385f09bd 94 Pfam PF02609 Exonuclease VII small subunit 23 73 6.7E-21 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CDC59_RS06115 d044c870f6055f62819673db385f09bd 94 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 22 76 7.4E-23 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CDC59_RS06115 d044c870f6055f62819673db385f09bd 94 Gene3D G3DSA:1.10.287.1040 20 83 2.3E-24 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CDC59_RS06115 d044c870f6055f62819673db385f09bd 94 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 22 82 15.111 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CDC59_RS08870 d0e8b172ea9201c66628c4ba384ea5d8 370 Pfam PF12857 TOBE-like domain 294 351 1.7E-17 T 29-03-2018 IPR024765 TOBE-like domain KEGG: 00920+3.6.3.25 CDC59_RS08870 d0e8b172ea9201c66628c4ba384ea5d8 370 SMART SM00382 27 214 1.5E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS08870 d0e8b172ea9201c66628c4ba384ea5d8 370 SUPERFAMILY SSF52540 3 245 4.79E-86 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS08870 d0e8b172ea9201c66628c4ba384ea5d8 370 Gene3D G3DSA:2.40.50.100 242 296 0.061 T 29-03-2018 CDC59_RS08870 d0e8b172ea9201c66628c4ba384ea5d8 370 Gene3D G3DSA:3.40.50.300 1 241 5.2E-78 T 29-03-2018 CDC59_RS08870 d0e8b172ea9201c66628c4ba384ea5d8 370 TIGRFAM TIGR00968 3a0106s01: sulfate ABC transporter, ATP-binding protein 3 241 9.4E-120 T 29-03-2018 IPR005666 Sulphate transport system permease protein 1 GO:0006810|GO:0016020|GO:0042626 KEGG: 00920+3.6.3.25 CDC59_RS08870 d0e8b172ea9201c66628c4ba384ea5d8 370 SUPERFAMILY SSF50331 239 356 4.76E-10 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CDC59_RS08870 d0e8b172ea9201c66628c4ba384ea5d8 370 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS08870 d0e8b172ea9201c66628c4ba384ea5d8 370 Pfam PF00005 ABC transporter 18 164 6.3E-37 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS12080 af8d7477f58f69136c53e1e28748f047 207 Pfam PF03458 UPF0126 domain 12 81 2.3E-19 T 29-03-2018 IPR005115 Uncharacterised domain UPF0126 CDC59_RS12080 af8d7477f58f69136c53e1e28748f047 207 Pfam PF03458 UPF0126 domain 100 173 2.2E-19 T 29-03-2018 IPR005115 Uncharacterised domain UPF0126 CDC59_RS16370 f726b3c4933a8f84276ed7ec007014e1 387 SUPERFAMILY SSF48256 20 387 4.45E-116 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CDC59_RS16370 f726b3c4933a8f84276ed7ec007014e1 387 PRINTS PR00143 Citrate synthase signature 263 283 3.2E-32 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CDC59_RS16370 f726b3c4933a8f84276ed7ec007014e1 387 PRINTS PR00143 Citrate synthase signature 188 203 3.2E-32 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CDC59_RS16370 f726b3c4933a8f84276ed7ec007014e1 387 PRINTS PR00143 Citrate synthase signature 340 354 3.2E-32 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CDC59_RS16370 f726b3c4933a8f84276ed7ec007014e1 387 PRINTS PR00143 Citrate synthase signature 320 336 3.2E-32 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CDC59_RS16370 f726b3c4933a8f84276ed7ec007014e1 387 PRINTS PR00143 Citrate synthase signature 210 238 3.2E-32 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CDC59_RS16370 f726b3c4933a8f84276ed7ec007014e1 387 Pfam PF00285 Citrate synthase, C-terminal domain 21 369 5.2E-103 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CDC59_RS16370 f726b3c4933a8f84276ed7ec007014e1 387 ProSitePatterns PS00480 Citrate synthase signature. 270 282 - T 29-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CDC59_RS16370 f726b3c4933a8f84276ed7ec007014e1 387 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 20 387 5.3E-146 T 29-03-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 CDC59_RS16370 f726b3c4933a8f84276ed7ec007014e1 387 Gene3D G3DSA:1.10.580.10 27 367 1.1E-74 T 29-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain CDC59_RS16370 f726b3c4933a8f84276ed7ec007014e1 387 PIRSF PIRSF001369 14 387 1.4E-101 T 29-03-2018 IPR024176 Citrate synthase, bacterial-type CDC59_RS00935 76f172e8a397b4e8986085f269c6b7d1 1334 TIGRFAM TIGR01238 D1pyr5carbox3: delta-1-pyrroline-5-carboxylate dehydrogenase 618 1125 7.0E-239 T 29-03-2018 IPR005933 Delta-1-pyrroline-5-carboxylate dehydrogenase 3 GO:0003842|GO:0006561|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 CDC59_RS00935 76f172e8a397b4e8986085f269c6b7d1 1334 Gene3D G3DSA:3.40.309.10 910 1108 2.0E-46 T 29-03-2018 CDC59_RS00935 76f172e8a397b4e8986085f269c6b7d1 1334 Gene3D G3DSA:1.10.1220.10 2 48 5.2E-5 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CDC59_RS00935 76f172e8a397b4e8986085f269c6b7d1 1334 Gene3D G3DSA:3.20.20.220 188 617 5.6E-108 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like CDC59_RS00935 76f172e8a397b4e8986085f269c6b7d1 1334 Gene3D G3DSA:3.40.605.10 652 909 3.9E-73 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CDC59_RS00935 76f172e8a397b4e8986085f269c6b7d1 1334 Pfam PF14850 DNA-binding domain of Proline dehydrogenase 156 267 1.9E-45 T 29-03-2018 IPR024082 Proline dehydrogenase PutA, domain II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 CDC59_RS00935 76f172e8a397b4e8986085f269c6b7d1 1334 Gene3D G3DSA:1.20.5.550 97 145 1.3E-18 T 29-03-2018 IPR024090 Proline dehydrogenase PutA, domain I GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 CDC59_RS00935 76f172e8a397b4e8986085f269c6b7d1 1334 SUPERFAMILY SSF51730 270 625 3.37E-120 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like CDC59_RS00935 76f172e8a397b4e8986085f269c6b7d1 1334 SUPERFAMILY SSF81935 96 269 9.15E-65 T 29-03-2018 IPR024089 Proline dehydrogenase PutA, domain I/II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 CDC59_RS00935 76f172e8a397b4e8986085f269c6b7d1 1334 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 918 929 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CDC59_RS00935 76f172e8a397b4e8986085f269c6b7d1 1334 PIRSF PIRSF000197 82 1334 0.0 T 29-03-2018 IPR025703 Bifunctional protein PutA GO:0003700|GO:0003842|GO:0004657|GO:0006355|GO:0010133 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 CDC59_RS00935 76f172e8a397b4e8986085f269c6b7d1 1334 SUPERFAMILY SSF53720 647 1125 1.09E-127 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CDC59_RS00935 76f172e8a397b4e8986085f269c6b7d1 1334 SUPERFAMILY SSF47598 3 45 1.45E-9 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 CDC59_RS00935 76f172e8a397b4e8986085f269c6b7d1 1334 Pfam PF00171 Aldehyde dehydrogenase family 669 1121 5.4E-112 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CDC59_RS00935 76f172e8a397b4e8986085f269c6b7d1 1334 Pfam PF01619 Proline dehydrogenase 278 576 5.0E-98 T 29-03-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 CDC59_RS05750 b482ba53ffd42d20fd211940780b5550 52 SUPERFAMILY SSF50475 4 47 1.35E-12 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CDC59_RS05750 b482ba53ffd42d20fd211940780b5550 52 Gene3D G3DSA:2.30.110.10 1 51 1.4E-9 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CDC59_RS05750 b482ba53ffd42d20fd211940780b5550 52 Pfam PF01613 Flavin reductase like domain 1 46 4.9E-9 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CDC59_RS06505 e3591b686938ae413750ac5be93dc3b1 335 PIRSF PIRSF500210 1 335 1.3E-128 T 29-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 CDC59_RS06505 e3591b686938ae413750ac5be93dc3b1 335 PIRSF PIRSF000904 1 335 9.7E-128 T 29-03-2018 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 CDC59_RS06505 e3591b686938ae413750ac5be93dc3b1 335 Gene3D G3DSA:3.30.540.10 8 199 1.1E-60 T 29-03-2018 CDC59_RS06505 e3591b686938ae413750ac5be93dc3b1 335 Hamap MF_01855 Fructose-1,6-bisphosphatase class 1 [fbp]. 4 333 47.504 T 29-03-2018 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 CDC59_RS06505 e3591b686938ae413750ac5be93dc3b1 335 Gene3D G3DSA:3.40.190.80 200 334 1.2E-56 T 29-03-2018 CDC59_RS06505 e3591b686938ae413750ac5be93dc3b1 335 Pfam PF00316 Fructose-1-6-bisphosphatase, N-terminal domain 5 193 3.7E-65 T 29-03-2018 IPR033391 Fructose-1-6-bisphosphatase class I, N-terminal KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 CDC59_RS06505 e3591b686938ae413750ac5be93dc3b1 335 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 205 232 2.0E-73 T 29-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 CDC59_RS06505 e3591b686938ae413750ac5be93dc3b1 335 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 179 202 2.0E-73 T 29-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 CDC59_RS06505 e3591b686938ae413750ac5be93dc3b1 335 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 29 56 2.0E-73 T 29-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 CDC59_RS06505 e3591b686938ae413750ac5be93dc3b1 335 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 66 92 2.0E-73 T 29-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 CDC59_RS06505 e3591b686938ae413750ac5be93dc3b1 335 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 148 171 2.0E-73 T 29-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 CDC59_RS06505 e3591b686938ae413750ac5be93dc3b1 335 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 307 332 2.0E-73 T 29-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 CDC59_RS06505 e3591b686938ae413750ac5be93dc3b1 335 SUPERFAMILY SSF56655 2 331 8.18E-118 T 29-03-2018 CDC59_RS15495 36dc143aa5d1dc7dfcdf345d01714809 293 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 63 106 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CDC59_RS15495 36dc143aa5d1dc7dfcdf345d01714809 293 Pfam PF06445 GyrI-like small molecule binding domain 141 293 6.1E-34 T 29-03-2018 IPR029442 GyrI-like small molecule binding domain CDC59_RS15495 36dc143aa5d1dc7dfcdf345d01714809 293 SUPERFAMILY SSF46689 10 60 8.96E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS15495 36dc143aa5d1dc7dfcdf345d01714809 293 SUPERFAMILY SSF55136 142 293 3.14E-31 T 29-03-2018 CDC59_RS15495 36dc143aa5d1dc7dfcdf345d01714809 293 SMART SM00871 140 293 1.2E-36 T 29-03-2018 IPR010499 Bacterial transcription activator, effector binding CDC59_RS15495 36dc143aa5d1dc7dfcdf345d01714809 293 SMART SM00342 26 110 8.7E-24 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CDC59_RS15495 36dc143aa5d1dc7dfcdf345d01714809 293 Gene3D G3DSA:3.20.80.10 137 293 1.5E-23 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain CDC59_RS15495 36dc143aa5d1dc7dfcdf345d01714809 293 Pfam PF12833 Helix-turn-helix domain 32 111 1.2E-21 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CDC59_RS15495 36dc143aa5d1dc7dfcdf345d01714809 293 Gene3D G3DSA:1.10.10.60 7 65 4.8E-10 T 29-03-2018 CDC59_RS15495 36dc143aa5d1dc7dfcdf345d01714809 293 Gene3D G3DSA:1.10.10.60 66 128 3.9E-13 T 29-03-2018 CDC59_RS15495 36dc143aa5d1dc7dfcdf345d01714809 293 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 79 94 4.3E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CDC59_RS15495 36dc143aa5d1dc7dfcdf345d01714809 293 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 94 110 4.3E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CDC59_RS15495 36dc143aa5d1dc7dfcdf345d01714809 293 SUPERFAMILY SSF46689 62 118 9.41E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS20220 acd2513134288c9394a230a5c3bfb56b 210 TIGRFAM TIGR02560 HrpB4: type III secretion protein HrpB4 7 210 1.5E-69 T 29-03-2018 IPR013393 Type III secretion protein HrpB4 CDC59_RS20220 acd2513134288c9394a230a5c3bfb56b 210 Pfam PF09502 Bacterial type III secretion protein (HrpB4) 18 204 8.6E-16 T 29-03-2018 IPR013393 Type III secretion protein HrpB4 CDC59_RS14045 c6a178774f2f5867a8593821ac937e5f 571 ProSitePatterns PS00455 Putative AMP-binding domain signature. 216 227 - T 29-03-2018 IPR020845 AMP-binding, conserved site CDC59_RS14045 c6a178774f2f5867a8593821ac937e5f 571 Gene3D G3DSA:3.30.300.30 460 566 1.5E-29 T 29-03-2018 CDC59_RS14045 c6a178774f2f5867a8593821ac937e5f 571 Pfam PF13193 AMP-binding enzyme C-terminal domain 474 549 1.0E-20 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CDC59_RS14045 c6a178774f2f5867a8593821ac937e5f 571 Gene3D G3DSA:2.30.38.10 376 458 1.1E-26 T 29-03-2018 CDC59_RS14045 c6a178774f2f5867a8593821ac937e5f 571 SUPERFAMILY SSF56801 20 561 4.45E-160 T 29-03-2018 CDC59_RS14045 c6a178774f2f5867a8593821ac937e5f 571 Gene3D G3DSA:3.40.50.980 221 375 7.5E-52 T 29-03-2018 CDC59_RS14045 c6a178774f2f5867a8593821ac937e5f 571 Pfam PF00501 AMP-binding enzyme 35 465 1.3E-105 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CDC59_RS14045 c6a178774f2f5867a8593821ac937e5f 571 Gene3D G3DSA:3.40.50.980 27 220 4.4E-42 T 29-03-2018 CDC59_RS21795 4c25f08f4821ce946f4faf5426bfaf81 675 Gene3D G3DSA:3.30.450.20 142 289 1.8E-21 T 29-03-2018 CDC59_RS21795 4c25f08f4821ce946f4faf5426bfaf81 675 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 408 520 4.2E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS21795 4c25f08f4821ce946f4faf5426bfaf81 675 Gene3D G3DSA:3.30.565.10 357 521 8.4E-48 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS21795 4c25f08f4821ce946f4faf5426bfaf81 675 SMART SM00448 546 662 3.7E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS21795 4c25f08f4821ce946f4faf5426bfaf81 675 Gene3D G3DSA:3.40.50.2300 533 675 2.1E-31 T 29-03-2018 CDC59_RS21795 4c25f08f4821ce946f4faf5426bfaf81 675 SUPERFAMILY SSF52172 544 669 7.26E-31 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS21795 4c25f08f4821ce946f4faf5426bfaf81 675 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 188 276 1.4E-9 T 29-03-2018 IPR000014 PAS domain CDC59_RS21795 4c25f08f4821ce946f4faf5426bfaf81 675 SUPERFAMILY SSF55785 147 268 7.25E-16 T 29-03-2018 IPR000014 PAS domain CDC59_RS21795 4c25f08f4821ce946f4faf5426bfaf81 675 Pfam PF08448 PAS fold 167 271 2.5E-12 T 29-03-2018 IPR013656 PAS fold-4 CDC59_RS21795 4c25f08f4821ce946f4faf5426bfaf81 675 Gene3D G3DSA:1.20.120.620 42 139 7.3E-10 T 29-03-2018 CDC59_RS21795 4c25f08f4821ce946f4faf5426bfaf81 675 Pfam PF13493 Domain of unknown function (DUF4118) 43 147 1.4E-7 T 29-03-2018 IPR025201 Sensor protein KdpD, transmembrane domain CDC59_RS21795 4c25f08f4821ce946f4faf5426bfaf81 675 Pfam PF00072 Response regulator receiver domain 548 659 3.9E-19 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS21795 4c25f08f4821ce946f4faf5426bfaf81 675 SUPERFAMILY SSF55874 352 523 4.32E-49 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS21795 4c25f08f4821ce946f4faf5426bfaf81 675 SUPERFAMILY SSF47384 282 363 4.9E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS21795 4c25f08f4821ce946f4faf5426bfaf81 675 Gene3D G3DSA:1.10.287.130 290 356 2.3E-17 T 29-03-2018 CDC59_RS21795 4c25f08f4821ce946f4faf5426bfaf81 675 SMART SM00387 408 521 5.6E-42 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS21795 4c25f08f4821ce946f4faf5426bfaf81 675 Pfam PF00512 His Kinase A (phospho-acceptor) domain 298 360 1.5E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS21795 4c25f08f4821ce946f4faf5426bfaf81 675 PRINTS PR00344 Bacterial sensor protein C-terminal signature 445 459 2.0E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS21795 4c25f08f4821ce946f4faf5426bfaf81 675 PRINTS PR00344 Bacterial sensor protein C-terminal signature 505 518 2.0E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS21795 4c25f08f4821ce946f4faf5426bfaf81 675 PRINTS PR00344 Bacterial sensor protein C-terminal signature 463 473 2.0E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS21795 4c25f08f4821ce946f4faf5426bfaf81 675 PRINTS PR00344 Bacterial sensor protein C-terminal signature 480 498 2.0E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS21795 4c25f08f4821ce946f4faf5426bfaf81 675 SMART SM00388 297 363 7.7E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS10120 5ef816db419f6a13c8fb42c2e1d4675c 188 SUPERFAMILY SSF46785 41 177 1.82E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS10120 5ef816db419f6a13c8fb42c2e1d4675c 188 PIRSF PIRSF036158 1 188 8.8E-87 T 29-03-2018 IPR014601 Transcriptional regulator with MarR-type HTH domain CDC59_RS10120 5ef816db419f6a13c8fb42c2e1d4675c 188 Gene3D G3DSA:1.10.10.10 36 182 2.6E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS10120 5ef816db419f6a13c8fb42c2e1d4675c 188 Pfam PF13463 Winged helix DNA-binding domain 70 135 8.6E-19 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS08065 507288d0ba6d4bec0dcd54aa563c12eb 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 67 4.2E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS08065 507288d0ba6d4bec0dcd54aa563c12eb 304 Gene3D G3DSA:3.40.190.10 181 275 2.3E-22 T 29-03-2018 CDC59_RS08065 507288d0ba6d4bec0dcd54aa563c12eb 304 Gene3D G3DSA:3.40.190.10 85 180 1.8E-19 T 29-03-2018 CDC59_RS08065 507288d0ba6d4bec0dcd54aa563c12eb 304 SUPERFAMILY SSF53850 93 297 9.87E-36 T 29-03-2018 CDC59_RS08065 507288d0ba6d4bec0dcd54aa563c12eb 304 SUPERFAMILY SSF46785 5 115 6.53E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS08065 507288d0ba6d4bec0dcd54aa563c12eb 304 Gene3D G3DSA:1.10.10.10 1 84 3.3E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS08065 507288d0ba6d4bec0dcd54aa563c12eb 304 Pfam PF03466 LysR substrate binding domain 92 298 2.3E-31 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS03155 502789c723e43a0dd4d9cf4da1073f87 400 Pfam PF12327 FtsZ family, C-terminal domain 221 315 2.6E-31 T 29-03-2018 IPR024757 Cell division protein FtsZ, C-terminal CDC59_RS03155 502789c723e43a0dd4d9cf4da1073f87 400 PRINTS PR00423 Cell division protein FtsZ signature 125 146 2.1E-45 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CDC59_RS03155 502789c723e43a0dd4d9cf4da1073f87 400 PRINTS PR00423 Cell division protein FtsZ signature 188 210 2.1E-45 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CDC59_RS03155 502789c723e43a0dd4d9cf4da1073f87 400 PRINTS PR00423 Cell division protein FtsZ signature 211 232 2.1E-45 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CDC59_RS03155 502789c723e43a0dd4d9cf4da1073f87 400 PRINTS PR00423 Cell division protein FtsZ signature 97 117 2.1E-45 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CDC59_RS03155 502789c723e43a0dd4d9cf4da1073f87 400 Gene3D G3DSA:3.40.50.1440 7 213 7.3E-36 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CDC59_RS03155 502789c723e43a0dd4d9cf4da1073f87 400 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 16 172 4.4E-34 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CDC59_RS03155 502789c723e43a0dd4d9cf4da1073f87 400 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 11 335 34.732 T 29-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 CDC59_RS03155 502789c723e43a0dd4d9cf4da1073f87 400 SUPERFAMILY SSF52490 16 207 7.59E-61 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CDC59_RS03155 502789c723e43a0dd4d9cf4da1073f87 400 SMART SM00865 206 324 4.2E-52 T 29-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 CDC59_RS03155 502789c723e43a0dd4d9cf4da1073f87 400 ProSitePatterns PS01135 FtsZ protein signature 2. 96 117 - T 29-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 CDC59_RS03155 502789c723e43a0dd4d9cf4da1073f87 400 SUPERFAMILY SSF55307 203 317 2.75E-39 T 29-03-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 CDC59_RS03155 502789c723e43a0dd4d9cf4da1073f87 400 Gene3D G3DSA:3.30.1330.20 214 324 1.6E-41 T 29-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 CDC59_RS03155 502789c723e43a0dd4d9cf4da1073f87 400 SMART SM00864 15 204 3.6E-100 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CDC59_RS03155 502789c723e43a0dd4d9cf4da1073f87 400 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 10 328 8.4E-117 T 29-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 CDC59_RS09460 22e87075072e3aacf817bea2a585d524 240 Pfam PF02308 MgtC family 21 141 2.1E-32 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CDC59_RS09460 22e87075072e3aacf817bea2a585d524 240 PRINTS PR01837 MgtC/SapB protein signature 43 61 8.0E-40 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CDC59_RS09460 22e87075072e3aacf817bea2a585d524 240 PRINTS PR01837 MgtC/SapB protein signature 69 91 8.0E-40 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CDC59_RS09460 22e87075072e3aacf817bea2a585d524 240 PRINTS PR01837 MgtC/SapB protein signature 96 120 8.0E-40 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CDC59_RS09460 22e87075072e3aacf817bea2a585d524 240 PRINTS PR01837 MgtC/SapB protein signature 24 43 8.0E-40 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CDC59_RS09460 22e87075072e3aacf817bea2a585d524 240 Gene3D G3DSA:3.40.1160.10 23 225 9.3E-4 T 29-03-2018 CDC59_RS19895 2086c94e65a0f7fd3320e745ffa424e6 584 TIGRFAM TIGR03262 PhnU2: putative 2-aminoethylphosphonate ABC transporter, permease protein 36 581 1.4E-233 T 29-03-2018 IPR017664 2-aminoethylphosphonate ABC transport system, permease protein, putative CDC59_RS19895 2086c94e65a0f7fd3320e745ffa424e6 584 SUPERFAMILY SSF161098 310 567 6.0E-33 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS19895 2086c94e65a0f7fd3320e745ffa424e6 584 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 399 571 1.0E-9 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS19895 2086c94e65a0f7fd3320e745ffa424e6 584 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 292 3.9E-15 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS19895 2086c94e65a0f7fd3320e745ffa424e6 584 Gene3D G3DSA:1.10.3720.10 32 295 2.8E-33 T 29-03-2018 CDC59_RS19895 2086c94e65a0f7fd3320e745ffa424e6 584 Gene3D G3DSA:1.10.3720.10 314 578 1.1E-27 T 29-03-2018 CDC59_RS19895 2086c94e65a0f7fd3320e745ffa424e6 584 SUPERFAMILY SSF161098 36 289 9.38E-45 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS04325 e61ce673fd8b2b360025f03ec7ac5a9f 454 SMART SM00382 224 447 0.0073 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS04325 e61ce673fd8b2b360025f03ec7ac5a9f 454 SUPERFAMILY SSF52540 81 415 4.47E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS04325 e61ce673fd8b2b360025f03ec7ac5a9f 454 Gene3D G3DSA:3.30.450.90 96 198 3.9E-37 T 29-03-2018 CDC59_RS04325 e61ce673fd8b2b360025f03ec7ac5a9f 454 Gene3D G3DSA:3.40.50.300 199 413 6.1E-21 T 29-03-2018 CDC59_RS04325 e61ce673fd8b2b360025f03ec7ac5a9f 454 Pfam PF00437 Type II/IV secretion system protein 101 376 1.3E-83 T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CDC59_RS21885 31f8f8df12dfbaa8aa91c6fee08e321d 445 Gene3D G3DSA:2.40.50.100 103 176 9.5E-20 T 29-03-2018 CDC59_RS21885 31f8f8df12dfbaa8aa91c6fee08e321d 445 Gene3D G3DSA:2.40.50.100 206 393 3.1E-5 T 29-03-2018 CDC59_RS21885 31f8f8df12dfbaa8aa91c6fee08e321d 445 SUPERFAMILY SSF111369 94 331 1.03E-56 T 29-03-2018 CDC59_RS21885 31f8f8df12dfbaa8aa91c6fee08e321d 445 Pfam PF13437 HlyD family secretion protein 215 317 9.5E-7 T 29-03-2018 CDC59_RS21885 31f8f8df12dfbaa8aa91c6fee08e321d 445 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 79 407 1.1E-73 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 CDC59_RS21885 31f8f8df12dfbaa8aa91c6fee08e321d 445 Pfam PF13533 Biotin-lipoyl like 104 152 1.0E-17 T 29-03-2018 CDC59_RS11485 c94c5d50d637d5da4a26c8f1d5a5b6a3 270 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 62 76 7.4E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDC59_RS11485 c94c5d50d637d5da4a26c8f1d5a5b6a3 270 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 76 92 7.4E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDC59_RS11485 c94c5d50d637d5da4a26c8f1d5a5b6a3 270 SUPERFAMILY SSF46785 37 114 2.18E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS11485 c94c5d50d637d5da4a26c8f1d5a5b6a3 270 SMART SM00866 122 264 1.7E-37 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CDC59_RS11485 c94c5d50d637d5da4a26c8f1d5a5b6a3 270 Gene3D G3DSA:3.40.1410.10 114 269 4.2E-38 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CDC59_RS11485 c94c5d50d637d5da4a26c8f1d5a5b6a3 270 Pfam PF07702 UTRA domain 125 263 1.2E-37 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CDC59_RS11485 c94c5d50d637d5da4a26c8f1d5a5b6a3 270 SMART SM00345 43 102 4.1E-22 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDC59_RS11485 c94c5d50d637d5da4a26c8f1d5a5b6a3 270 Pfam PF00392 Bacterial regulatory proteins, gntR family 39 102 4.1E-22 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDC59_RS11485 c94c5d50d637d5da4a26c8f1d5a5b6a3 270 Gene3D G3DSA:1.10.10.10 33 104 2.3E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS11485 c94c5d50d637d5da4a26c8f1d5a5b6a3 270 SUPERFAMILY SSF64288 91 269 1.88E-42 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CDC59_RS11290 755883e0515124b12892498f6863148e 507 PIRSF PIRSF001394 1 507 5.0E-218 T 29-03-2018 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 CDC59_RS11290 755883e0515124b12892498f6863148e 507 SUPERFAMILY SSF117457 320 489 7.45E-62 T 29-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CDC59_RS11290 755883e0515124b12892498f6863148e 507 Pfam PF05683 Fumarase C-terminus 289 490 4.5E-82 T 29-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CDC59_RS11290 755883e0515124b12892498f6863148e 507 Gene3D G3DSA:3.20.130.10 316 489 1.2E-64 T 29-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CDC59_RS11290 755883e0515124b12892498f6863148e 507 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 12 285 7.7E-65 T 29-03-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 CDC59_RS11290 755883e0515124b12892498f6863148e 507 Pfam PF05681 Fumarate hydratase (Fumerase) 11 285 2.9E-100 T 29-03-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 CDC59_RS11290 755883e0515124b12892498f6863148e 507 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 327 489 1.9E-47 T 29-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CDC59_RS03365 9fe68642e89ebede2e468e077a392ed6 154 Pfam PF09917 Uncharacterized protein conserved in bacteria (DUF2147) 36 153 6.0E-33 T 29-03-2018 IPR019223 Domain of unknown function DUF2147 CDC59_RS07590 9aae82669fca33fd40ab57b843af9aef 366 TIGRFAM TIGR00698 TIGR00698: conserved hypothetical protein 32 360 5.2E-76 T 29-03-2018 IPR004630 Uncharacterised protein family UPF0324, bacteria GO:0016021 CDC59_RS07590 9aae82669fca33fd40ab57b843af9aef 366 Pfam PF03601 Conserved hypothetical protein 698 27 342 1.7E-79 T 29-03-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 CDC59_RS20915 11543e9561e06dab437b7ecb78451f03 319 Gene3D G3DSA:1.10.10.60 272 319 1.4E-12 T 29-03-2018 CDC59_RS20915 11543e9561e06dab437b7ecb78451f03 319 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 285 300 7.6E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CDC59_RS20915 11543e9561e06dab437b7ecb78451f03 319 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 300 316 7.6E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CDC59_RS20915 11543e9561e06dab437b7ecb78451f03 319 Gene3D G3DSA:1.10.10.60 213 271 6.5E-7 T 29-03-2018 CDC59_RS20915 11543e9561e06dab437b7ecb78451f03 319 Pfam PF12833 Helix-turn-helix domain 239 318 4.1E-20 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CDC59_RS20915 11543e9561e06dab437b7ecb78451f03 319 SMART SM00342 233 316 2.4E-23 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CDC59_RS20915 11543e9561e06dab437b7ecb78451f03 319 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 270 312 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CDC59_RS20915 11543e9561e06dab437b7ecb78451f03 319 SUPERFAMILY SSF46689 270 318 3.72E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS19590 ed8c8b10d96129e33f40237a21a00b13 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS19590 ed8c8b10d96129e33f40237a21a00b13 328 Pfam PF05598 Transposase domain (DUF772) 51 126 3.1E-23 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS23425 ed8c8b10d96129e33f40237a21a00b13 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS23425 ed8c8b10d96129e33f40237a21a00b13 328 Pfam PF05598 Transposase domain (DUF772) 51 126 3.1E-23 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS10855 ed8c8b10d96129e33f40237a21a00b13 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS10855 ed8c8b10d96129e33f40237a21a00b13 328 Pfam PF05598 Transposase domain (DUF772) 51 126 3.1E-23 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS23625 ed8c8b10d96129e33f40237a21a00b13 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS23625 ed8c8b10d96129e33f40237a21a00b13 328 Pfam PF05598 Transposase domain (DUF772) 51 126 3.1E-23 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS16620 ed8c8b10d96129e33f40237a21a00b13 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS16620 ed8c8b10d96129e33f40237a21a00b13 328 Pfam PF05598 Transposase domain (DUF772) 51 126 3.1E-23 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS19695 ed8c8b10d96129e33f40237a21a00b13 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS19695 ed8c8b10d96129e33f40237a21a00b13 328 Pfam PF05598 Transposase domain (DUF772) 51 126 3.1E-23 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS19170 662243817dcca67bd330332d8462df42 554 TIGRFAM TIGR01194 cyc_pep_trnsptr: cyclic peptide transporter 10 535 2.5E-95 T 29-03-2018 IPR005898 Cyclic peptide transporter GO:0005524|GO:0015197|GO:0015833|GO:0016021 CDC59_RS19170 662243817dcca67bd330332d8462df42 554 SUPERFAMILY SSF90123 16 300 8.11E-22 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CDC59_RS19170 662243817dcca67bd330332d8462df42 554 Gene3D G3DSA:3.40.50.300 324 540 1.2E-35 T 29-03-2018 CDC59_RS19170 662243817dcca67bd330332d8462df42 554 Pfam PF00005 ABC transporter 349 483 3.3E-21 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS19170 662243817dcca67bd330332d8462df42 554 Pfam PF00664 ABC transporter transmembrane region 34 211 6.8E-10 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CDC59_RS19170 662243817dcca67bd330332d8462df42 554 Gene3D G3DSA:1.20.1560.10 2 316 1.0E-18 T 29-03-2018 CDC59_RS19170 662243817dcca67bd330332d8462df42 554 SUPERFAMILY SSF52540 326 535 2.53E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS19170 662243817dcca67bd330332d8462df42 554 SMART SM00382 356 532 6.3E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS15860 afa06d2a46b19b105da295a8d39e129d 488 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 1 485 3.5E-164 T 29-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 CDC59_RS15860 afa06d2a46b19b105da295a8d39e129d 488 Pfam PF02637 GatB domain 334 485 1.1E-53 T 29-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 CDC59_RS15860 afa06d2a46b19b105da295a8d39e129d 488 SMART SM00845 333 485 1.1E-83 T 29-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 CDC59_RS15860 afa06d2a46b19b105da295a8d39e129d 488 SUPERFAMILY SSF55931 4 301 1.24E-117 T 29-03-2018 CDC59_RS15860 afa06d2a46b19b105da295a8d39e129d 488 Gene3D G3DSA:1.10.10.410 425 486 1.6E-24 T 29-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal CDC59_RS15860 afa06d2a46b19b105da295a8d39e129d 488 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 149 163 - T 29-03-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 CDC59_RS15860 afa06d2a46b19b105da295a8d39e129d 488 Pfam PF02934 GatB/GatE catalytic domain 5 293 6.9E-111 T 29-03-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 CDC59_RS15860 afa06d2a46b19b105da295a8d39e129d 488 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 2 486 38.323 T 29-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 CDC59_RS15860 afa06d2a46b19b105da295a8d39e129d 488 SUPERFAMILY SSF89095 302 408 3.79E-30 T 29-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 CDC59_RS22255 1fb6742b4a78b6c82d41e1e44f355951 234 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 57 77 - T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS22255 1fb6742b4a78b6c82d41e1e44f355951 234 Pfam PF07963 Prokaryotic N-terminal methylation motif 55 78 5.6E-7 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS22255 1fb6742b4a78b6c82d41e1e44f355951 234 Gene3D G3DSA:3.30.700.10 59 234 4.0E-18 T 29-03-2018 CDC59_RS22255 1fb6742b4a78b6c82d41e1e44f355951 234 SUPERFAMILY SSF54523 59 197 3.77E-21 T 29-03-2018 CDC59_RS22255 1fb6742b4a78b6c82d41e1e44f355951 234 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 57 79 4.7E-7 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS22255 1fb6742b4a78b6c82d41e1e44f355951 234 Pfam PF12019 Type II transport protein GspH 94 221 6.3E-23 T 29-03-2018 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 CDC59_RS20715 02e8893b9c86b67701590f7e91b29497 151 Gene3D G3DSA:3.40.140.10 1 137 2.4E-25 T 29-03-2018 CDC59_RS20715 02e8893b9c86b67701590f7e91b29497 151 SMART SM00232 1 132 5.0E-14 T 29-03-2018 IPR000555 JAB1/MPN/MOV34 metalloenzyme domain GO:0005515 CDC59_RS20715 02e8893b9c86b67701590f7e91b29497 151 Pfam PF14464 Prokaryotic homologs of the JAB domain 7 108 1.6E-23 T 29-03-2018 IPR028090 JAB domain, prokaryotic CDC59_RS20715 02e8893b9c86b67701590f7e91b29497 151 SUPERFAMILY SSF102712 1 129 7.45E-25 T 29-03-2018 CDC59_RS18090 3bb97dd74a2b380ca0bd7d43e9f8b496 278 SUPERFAMILY SSF54534 137 234 6.34E-13 T 29-03-2018 CDC59_RS18090 3bb97dd74a2b380ca0bd7d43e9f8b496 278 SUPERFAMILY SSF109998 30 165 4.32E-9 T 29-03-2018 IPR027304 Trigger factor/SurA domain CDC59_RS18090 3bb97dd74a2b380ca0bd7d43e9f8b496 278 Pfam PF13145 PPIC-type PPIASE domain 117 248 2.8E-13 T 29-03-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 CDC59_RS18090 3bb97dd74a2b380ca0bd7d43e9f8b496 278 Gene3D G3DSA:3.10.50.40 131 257 1.1E-16 T 29-03-2018 CDC59_RS13115 55e6bee3b6c0129175b1bbe216fa06ba 171 SMART SM00900 85 166 4.2E-12 T 29-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 CDC59_RS13115 55e6bee3b6c0129175b1bbe216fa06ba 171 Pfam PF04205 FMN-binding domain 85 163 4.8E-10 T 29-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 CDC59_RS02230 10e012f8871711fae3c9656e785bec5c 104 Gene3D G3DSA:3.30.70.600 4 104 1.9E-37 T 29-03-2018 IPR027486 Ribosomal protein S10 domain CDC59_RS02230 10e012f8871711fae3c9656e785bec5c 104 ProSitePatterns PS00361 Ribosomal protein S10 signature. 30 45 - T 29-03-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS02230 10e012f8871711fae3c9656e785bec5c 104 SUPERFAMILY SSF54999 6 103 1.57E-38 T 29-03-2018 IPR027486 Ribosomal protein S10 domain CDC59_RS02230 10e012f8871711fae3c9656e785bec5c 104 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 5 102 2.4E-46 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS02230 10e012f8871711fae3c9656e785bec5c 104 PRINTS PR00971 Ribosomal protein S10 family signature 6 19 3.7E-18 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS02230 10e012f8871711fae3c9656e785bec5c 104 PRINTS PR00971 Ribosomal protein S10 family signature 41 56 3.7E-18 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS02230 10e012f8871711fae3c9656e785bec5c 104 PRINTS PR00971 Ribosomal protein S10 family signature 62 76 3.7E-18 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS02230 10e012f8871711fae3c9656e785bec5c 104 SMART SM01403 8 102 1.2E-57 T 29-03-2018 IPR027486 Ribosomal protein S10 domain CDC59_RS02230 10e012f8871711fae3c9656e785bec5c 104 Pfam PF00338 Ribosomal protein S10p/S20e 8 102 2.3E-36 T 29-03-2018 IPR027486 Ribosomal protein S10 domain CDC59_RS02230 10e012f8871711fae3c9656e785bec5c 104 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 4 103 27.927 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS22045 868e4d274d4f7f806882ef27409efb42 856 SUPERFAMILY SSF51905 193 336 3.81E-39 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS22045 868e4d274d4f7f806882ef27409efb42 856 SUPERFAMILY SSF51905 3 162 3.81E-39 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS22045 868e4d274d4f7f806882ef27409efb42 856 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 145 163 6.2E-19 T 29-03-2018 CDC59_RS22045 868e4d274d4f7f806882ef27409efb42 856 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 6.2E-19 T 29-03-2018 CDC59_RS22045 868e4d274d4f7f806882ef27409efb42 856 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 118 6.2E-19 T 29-03-2018 CDC59_RS22045 868e4d274d4f7f806882ef27409efb42 856 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 236 252 6.2E-19 T 29-03-2018 CDC59_RS22045 868e4d274d4f7f806882ef27409efb42 856 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 263 285 6.2E-19 T 29-03-2018 CDC59_RS22045 868e4d274d4f7f806882ef27409efb42 856 Gene3D G3DSA:3.50.50.60 2 98 8.5E-12 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS22045 868e4d274d4f7f806882ef27409efb42 856 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 5 803 0.0 T 29-03-2018 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 CDC59_RS22045 868e4d274d4f7f806882ef27409efb42 856 Gene3D G3DSA:3.30.413.10 635 820 7.6E-38 T 29-03-2018 CDC59_RS22045 868e4d274d4f7f806882ef27409efb42 856 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 103 112 1.6E-8 T 29-03-2018 CDC59_RS22045 868e4d274d4f7f806882ef27409efb42 856 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 237 251 1.6E-8 T 29-03-2018 CDC59_RS22045 868e4d274d4f7f806882ef27409efb42 856 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 145 170 1.6E-8 T 29-03-2018 CDC59_RS22045 868e4d274d4f7f806882ef27409efb42 856 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 278 285 1.6E-8 T 29-03-2018 CDC59_RS22045 868e4d274d4f7f806882ef27409efb42 856 Gene3D G3DSA:3.50.50.60 99 203 1.1E-25 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS22045 868e4d274d4f7f806882ef27409efb42 856 PRINTS PR00397 Sirohaem Fe-binding site signature 683 701 1.1E-6 T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CDC59_RS22045 868e4d274d4f7f806882ef27409efb42 856 PRINTS PR00397 Sirohaem Fe-binding site signature 640 658 1.1E-6 T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CDC59_RS22045 868e4d274d4f7f806882ef27409efb42 856 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 683 699 - T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CDC59_RS22045 868e4d274d4f7f806882ef27409efb42 856 Pfam PF04324 BFD-like [2Fe-2S] binding domain 428 475 3.3E-10 T 29-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain CDC59_RS22045 868e4d274d4f7f806882ef27409efb42 856 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 288 4.2E-50 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS22045 868e4d274d4f7f806882ef27409efb42 856 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 636 756 7.0E-16 T 29-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CDC59_RS22045 868e4d274d4f7f806882ef27409efb42 856 PIRSF PIRSF037149 1 839 0.0 T 29-03-2018 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 CDC59_RS22045 868e4d274d4f7f806882ef27409efb42 856 Gene3D G3DSA:3.90.480.10 313 632 1.0E-17 T 29-03-2018 CDC59_RS22045 868e4d274d4f7f806882ef27409efb42 856 Gene3D G3DSA:3.50.50.60 258 312 1.9E-8 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS22045 868e4d274d4f7f806882ef27409efb42 856 SUPERFAMILY SSF56014 637 813 1.44E-49 T 29-03-2018 CDC59_RS22045 868e4d274d4f7f806882ef27409efb42 856 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 564 626 9.6E-12 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CDC59_RS22045 868e4d274d4f7f806882ef27409efb42 856 SUPERFAMILY SSF55124 506 645 1.8E-26 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CDC59_RS22045 868e4d274d4f7f806882ef27409efb42 856 Gene3D G3DSA:3.30.9.10 204 257 0.0043 T 29-03-2018 CDC59_RS21245 e9f6164dcf5fedcebf29b07a23c880d1 422 Pfam PF12536 Patatin phospholipase 296 400 5.9E-36 T 29-03-2018 IPR021095 Protein of unknown function DUF3734 CDC59_RS21245 e9f6164dcf5fedcebf29b07a23c880d1 422 Pfam PF01734 Patatin-like phospholipase 45 258 1.1E-22 T 29-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 CDC59_RS21245 e9f6164dcf5fedcebf29b07a23c880d1 422 SUPERFAMILY SSF52151 42 114 1.12E-53 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CDC59_RS21245 e9f6164dcf5fedcebf29b07a23c880d1 422 SUPERFAMILY SSF52151 165 327 1.12E-53 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CDC59_RS21245 e9f6164dcf5fedcebf29b07a23c880d1 422 Gene3D G3DSA:3.40.1090.10 30 357 2.1E-41 T 29-03-2018 CDC59_RS22635 99e7f7e564a6f39d20cf332f0acdbebb 112 Pfam PF00593 TonB dependent receptor 22 111 1.1E-10 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CDC59_RS22635 99e7f7e564a6f39d20cf332f0acdbebb 112 Gene3D G3DSA:2.40.160.40 20 112 6.3E-12 T 29-03-2018 CDC59_RS22635 99e7f7e564a6f39d20cf332f0acdbebb 112 SUPERFAMILY SSF56935 24 111 6.41E-15 T 29-03-2018 CDC59_RS00545 6122d4a2d7365629f4e934df22750581 261 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 12 245 3.5E-37 T 29-03-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CDC59_RS00545 6122d4a2d7365629f4e934df22750581 261 Gene3D G3DSA:3.40.50.1580 1 257 4.3E-52 T 29-03-2018 CDC59_RS00545 6122d4a2d7365629f4e934df22750581 261 Pfam PF01048 Phosphorylase superfamily 11 249 1.5E-48 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CDC59_RS00545 6122d4a2d7365629f4e934df22750581 261 SUPERFAMILY SSF53167 10 245 2.36E-59 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CDC59_RS11145 afa46bd0d2b7ad322a9d24183d0cbb3d 300 Pfam PF05118 Aspartyl/Asparaginyl beta-hydroxylase 70 223 1.9E-48 T 29-03-2018 IPR007803 Aspartyl/asparaginy/proline hydroxylase GO:0018193 CDC59_RS11145 afa46bd0d2b7ad322a9d24183d0cbb3d 300 Gene3D G3DSA:2.60.120.330 61 246 2.0E-45 T 29-03-2018 IPR027443 Isopenicillin N synthase-like CDC59_RS11145 afa46bd0d2b7ad322a9d24183d0cbb3d 300 SUPERFAMILY SSF51197 100 222 1.35E-17 T 29-03-2018 CDC59_RS08235 aaccd25c8bf809d6b4da6fe32b8cf8f5 249 Pfam PF00588 SpoU rRNA Methylase family 97 237 1.6E-40 T 29-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CDC59_RS08235 aaccd25c8bf809d6b4da6fe32b8cf8f5 249 SUPERFAMILY SSF75217 87 244 3.14E-49 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases CDC59_RS08235 aaccd25c8bf809d6b4da6fe32b8cf8f5 249 Gene3D G3DSA:3.40.1280.10 86 244 1.8E-47 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CDC59_RS08235 aaccd25c8bf809d6b4da6fe32b8cf8f5 249 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 6 80 3.3E-18 T 29-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CDC59_RS08235 aaccd25c8bf809d6b4da6fe32b8cf8f5 249 SUPERFAMILY SSF55315 2 78 6.47E-18 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like CDC59_RS08235 aaccd25c8bf809d6b4da6fe32b8cf8f5 249 Hamap MF_01887 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB [rlmB]. 4 244 45.401 T 29-03-2018 IPR024915 23S rRNA (guanosine-2-O-)-methyltransferase RlmB CDC59_RS08235 aaccd25c8bf809d6b4da6fe32b8cf8f5 249 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 5 243 1.0E-76 T 29-03-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 CDC59_RS08235 aaccd25c8bf809d6b4da6fe32b8cf8f5 249 SMART SM00967 6 82 3.6E-19 T 29-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CDC59_RS08235 aaccd25c8bf809d6b4da6fe32b8cf8f5 249 Gene3D G3DSA:3.30.1330.30 1 77 8.1E-16 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like CDC59_RS06445 f5e608763988ac5f2571b6884234f8f2 311 Pfam PF08340 Domain of unknown function (DUF1732) 227 311 2.9E-32 T 29-03-2018 IPR013551 Domain of unknown function DUF1732 CDC59_RS06445 f5e608763988ac5f2571b6884234f8f2 311 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 1 311 7.2E-70 T 29-03-2018 IPR005229 Conserved hypothetical protein CHP00255 CDC59_RS06445 f5e608763988ac5f2571b6884234f8f2 311 Pfam PF03755 YicC-like family, N-terminal region 2 165 4.8E-41 T 29-03-2018 IPR013527 YicC-like, N-terminal CDC59_RS04340 025ba3ad5d031987a24da466ca3daf64 622 Pfam PF00263 Bacterial type II and III secretion system protein 332 501 7.0E-42 T 29-03-2018 IPR004846 Type II/III secretion system GO:0009306 CDC59_RS04340 025ba3ad5d031987a24da466ca3daf64 622 Pfam PF13629 Pilus formation protein N terminal region 97 165 2.9E-19 T 29-03-2018 IPR032789 Pilus formation protein, N-terminal CDC59_RS04340 025ba3ad5d031987a24da466ca3daf64 622 PRINTS PR00811 Bacterial general secretion pathway protein D signature 488 502 2.2E-12 T 29-03-2018 IPR001775 GspD/PilQ family CDC59_RS04340 025ba3ad5d031987a24da466ca3daf64 622 PRINTS PR00811 Bacterial general secretion pathway protein D signature 326 350 2.2E-12 T 29-03-2018 IPR001775 GspD/PilQ family CDC59_RS04340 025ba3ad5d031987a24da466ca3daf64 622 PRINTS PR00811 Bacterial general secretion pathway protein D signature 465 483 2.2E-12 T 29-03-2018 IPR001775 GspD/PilQ family CDC59_RS04340 025ba3ad5d031987a24da466ca3daf64 622 PRINTS PR00811 Bacterial general secretion pathway protein D signature 267 277 2.2E-12 T 29-03-2018 IPR001775 GspD/PilQ family CDC59_RS04340 025ba3ad5d031987a24da466ca3daf64 622 PRINTS PR00811 Bacterial general secretion pathway protein D signature 363 373 2.2E-12 T 29-03-2018 IPR001775 GspD/PilQ family CDC59_RS23745 0748dae0605c91d5373906e670a206d9 298 Gene3D G3DSA:1.10.10.10 3 93 1.2E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS23745 0748dae0605c91d5373906e670a206d9 298 Pfam PF03466 LysR substrate binding domain 88 293 7.5E-39 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS23745 0748dae0605c91d5373906e670a206d9 298 SUPERFAMILY SSF46785 5 112 5.46E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS23745 0748dae0605c91d5373906e670a206d9 298 Gene3D G3DSA:3.40.190.10 179 264 1.5E-20 T 29-03-2018 CDC59_RS23745 0748dae0605c91d5373906e670a206d9 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 1.1E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS23745 0748dae0605c91d5373906e670a206d9 298 SUPERFAMILY SSF53850 88 297 4.34E-40 T 29-03-2018 CDC59_RS23745 0748dae0605c91d5373906e670a206d9 298 Gene3D G3DSA:3.40.190.10 94 178 5.3E-14 T 29-03-2018 CDC59_RS23745 0748dae0605c91d5373906e670a206d9 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 5.9E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS23745 0748dae0605c91d5373906e670a206d9 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 5.9E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS23745 0748dae0605c91d5373906e670a206d9 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 5.9E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS05885 ebfdf0fb9816088b7427164ff3d41785 949 Gene3D G3DSA:3.20.20.70 28 308 6.8E-57 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS05885 ebfdf0fb9816088b7427164ff3d41785 949 SUPERFAMILY SSF88713 543 681 5.4E-5 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CDC59_RS05885 ebfdf0fb9816088b7427164ff3d41785 949 SUPERFAMILY SSF88713 718 791 5.4E-5 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CDC59_RS05885 ebfdf0fb9816088b7427164ff3d41785 949 Pfam PF03537 Glycoside-hydrolase family GH114 55 286 3.9E-24 T 29-03-2018 IPR004352 Glycoside-hydrolase family GH114, TIM-barrel domain CDC59_RS05885 ebfdf0fb9816088b7427164ff3d41785 949 Gene3D G3DSA:3.20.20.370 511 796 1.4E-15 T 29-03-2018 CDC59_RS05885 ebfdf0fb9816088b7427164ff3d41785 949 SUPERFAMILY SSF51445 42 298 1.66E-45 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CDC59_RS05885 ebfdf0fb9816088b7427164ff3d41785 949 PIRSF PIRSF029570 1 949 0.0 T 29-03-2018 IPR016925 Uncharacterised conserved protein UCP029570 CDC59_RS21915 77e4e075947385a3eebeb6038c1fdace 449 Gene3D G3DSA:3.30.70.270 262 424 6.6E-59 T 29-03-2018 CDC59_RS21915 77e4e075947385a3eebeb6038c1fdace 449 SMART SM00091 6 72 4.3E-10 T 29-03-2018 IPR000014 PAS domain CDC59_RS21915 77e4e075947385a3eebeb6038c1fdace 449 SMART SM00091 132 200 0.048 T 29-03-2018 IPR000014 PAS domain CDC59_RS21915 77e4e075947385a3eebeb6038c1fdace 449 Pfam PF08447 PAS fold 29 106 2.4E-13 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 CDC59_RS21915 77e4e075947385a3eebeb6038c1fdace 449 Pfam PF08447 PAS fold 155 243 3.5E-19 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 CDC59_RS21915 77e4e075947385a3eebeb6038c1fdace 449 Gene3D G3DSA:3.30.450.20 2 122 1.1E-27 T 29-03-2018 CDC59_RS21915 77e4e075947385a3eebeb6038c1fdace 449 SUPERFAMILY SSF55785 3 118 3.87E-23 T 29-03-2018 IPR000014 PAS domain CDC59_RS21915 77e4e075947385a3eebeb6038c1fdace 449 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 5 124 1.0E-22 T 29-03-2018 IPR000014 PAS domain CDC59_RS21915 77e4e075947385a3eebeb6038c1fdace 449 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 129 251 2.7E-9 T 29-03-2018 IPR000014 PAS domain CDC59_RS21915 77e4e075947385a3eebeb6038c1fdace 449 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 259 416 2.2E-42 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS21915 77e4e075947385a3eebeb6038c1fdace 449 SMART SM00267 250 422 1.1E-57 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS21915 77e4e075947385a3eebeb6038c1fdace 449 SUPERFAMILY SSF55073 266 420 6.98E-47 T 29-03-2018 IPR029787 Nucleotide cyclase CDC59_RS21915 77e4e075947385a3eebeb6038c1fdace 449 SMART SM00086 79 120 7.4E-4 T 29-03-2018 IPR001610 PAC motif CDC59_RS21915 77e4e075947385a3eebeb6038c1fdace 449 SMART SM00086 207 250 0.0052 T 29-03-2018 IPR001610 PAC motif CDC59_RS21915 77e4e075947385a3eebeb6038c1fdace 449 Gene3D G3DSA:3.30.450.20 123 261 9.0E-29 T 29-03-2018 CDC59_RS21915 77e4e075947385a3eebeb6038c1fdace 449 Pfam PF00990 Diguanylate cyclase, GGDEF domain 261 416 3.2E-48 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS21915 77e4e075947385a3eebeb6038c1fdace 449 SUPERFAMILY SSF55785 117 248 3.38E-20 T 29-03-2018 IPR000014 PAS domain CDC59_RS06760 cd4889a4a2c967aa9550ee8028efc6aa 418 Pfam PF16491 CAAX prenyl protease N-terminal, five membrane helices 26 204 2.6E-56 T 29-03-2018 IPR032456 CAAX prenyl protease 1, N-terminal KEGG: 00900+3.4.24.84 CDC59_RS06760 cd4889a4a2c967aa9550ee8028efc6aa 418 Gene3D G3DSA:3.30.2010.10 203 285 7.6E-23 T 29-03-2018 CDC59_RS06760 cd4889a4a2c967aa9550ee8028efc6aa 418 Pfam PF01435 Peptidase family M48 207 414 8.4E-38 T 29-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CDC59_RS09290 b5f054f5a3a33f5b3c614ca7b7937793 487 Gene3D G3DSA:3.20.20.70 1 484 1.4E-119 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS09290 b5f054f5a3a33f5b3c614ca7b7937793 487 Pfam PF00571 CBS domain 94 138 1.1E-8 T 29-03-2018 IPR000644 CBS domain CDC59_RS09290 b5f054f5a3a33f5b3c614ca7b7937793 487 Pfam PF00571 CBS domain 153 202 4.0E-9 T 29-03-2018 IPR000644 CBS domain CDC59_RS09290 b5f054f5a3a33f5b3c614ca7b7937793 487 SUPERFAMILY SSF54631 94 202 1.15E-28 T 29-03-2018 CDC59_RS09290 b5f054f5a3a33f5b3c614ca7b7937793 487 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 7 473 1.8E-164 T 29-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 CDC59_RS09290 b5f054f5a3a33f5b3c614ca7b7937793 487 PIRSF PIRSF000130 1 487 5.9E-206 T 29-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CDC59_RS09290 b5f054f5a3a33f5b3c614ca7b7937793 487 SUPERFAMILY SSF51412 215 477 1.7E-126 T 29-03-2018 CDC59_RS09290 b5f054f5a3a33f5b3c614ca7b7937793 487 SUPERFAMILY SSF51412 2 89 1.7E-126 T 29-03-2018 CDC59_RS09290 b5f054f5a3a33f5b3c614ca7b7937793 487 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 293 305 - T 29-03-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 CDC59_RS09290 b5f054f5a3a33f5b3c614ca7b7937793 487 SMART SM00116 156 204 4.9E-11 T 29-03-2018 IPR000644 CBS domain CDC59_RS09290 b5f054f5a3a33f5b3c614ca7b7937793 487 SMART SM00116 95 142 3.8E-9 T 29-03-2018 IPR000644 CBS domain CDC59_RS09290 b5f054f5a3a33f5b3c614ca7b7937793 487 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 7 486 84.171 T 29-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CDC59_RS09290 b5f054f5a3a33f5b3c614ca7b7937793 487 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 7 455 3.4E-191 T 29-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CDC59_RS09290 b5f054f5a3a33f5b3c614ca7b7937793 487 SMART SM01240 6 473 0.0 T 29-03-2018 CDC59_RS15890 88384fcf7c8bfce6cb72192d3ba1bfe6 221 Gene3D G3DSA:1.10.10.10 163 220 1.2E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS15890 88384fcf7c8bfce6cb72192d3ba1bfe6 221 Pfam PF04255 Protein of unknown function (DUF433) 163 216 1.2E-6 T 29-03-2018 IPR007367 Protein of unknown function DUF433 CDC59_RS18690 eaffddc7a895c6ba91b1359721f830a4 1064 SUPERFAMILY SSF82866 816 1041 1.19E-57 T 29-03-2018 CDC59_RS18690 eaffddc7a895c6ba91b1359721f830a4 1064 Gene3D G3DSA:1.20.1640.10 297 519 6.2E-38 T 29-03-2018 CDC59_RS18690 eaffddc7a895c6ba91b1359721f830a4 1064 SUPERFAMILY SSF82714 193 275 1.96E-19 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS18690 eaffddc7a895c6ba91b1359721f830a4 1064 SUPERFAMILY SSF82714 730 814 1.31E-15 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS18690 eaffddc7a895c6ba91b1359721f830a4 1064 Gene3D G3DSA:1.20.1640.10 819 1039 1.4E-40 T 29-03-2018 CDC59_RS18690 eaffddc7a895c6ba91b1359721f830a4 1064 Gene3D G3DSA:3.30.2090.10 190 277 5.2E-21 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS18690 eaffddc7a895c6ba91b1359721f830a4 1064 SUPERFAMILY SSF82693 42 127 9.16E-23 T 29-03-2018 CDC59_RS18690 eaffddc7a895c6ba91b1359721f830a4 1064 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 1 1046 0.0 T 29-03-2018 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 CDC59_RS18690 eaffddc7a895c6ba91b1359721f830a4 1064 PRINTS PR00702 Acriflavin resistance protein family signature 553 570 2.0E-20 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS18690 eaffddc7a895c6ba91b1359721f830a4 1064 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 2.0E-20 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS18690 eaffddc7a895c6ba91b1359721f830a4 1064 PRINTS PR00702 Acriflavin resistance protein family signature 339 362 2.0E-20 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS18690 eaffddc7a895c6ba91b1359721f830a4 1064 PRINTS PR00702 Acriflavin resistance protein family signature 480 503 2.0E-20 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS18690 eaffddc7a895c6ba91b1359721f830a4 1064 PRINTS PR00702 Acriflavin resistance protein family signature 366 387 2.0E-20 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS18690 eaffddc7a895c6ba91b1359721f830a4 1064 Gene3D G3DSA:3.30.2090.10 729 818 2.1E-20 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS18690 eaffddc7a895c6ba91b1359721f830a4 1064 SUPERFAMILY SSF82693 155 191 3.84E-20 T 29-03-2018 CDC59_RS18690 eaffddc7a895c6ba91b1359721f830a4 1064 SUPERFAMILY SSF82693 277 333 3.84E-20 T 29-03-2018 CDC59_RS18690 eaffddc7a895c6ba91b1359721f830a4 1064 Pfam PF00873 AcrB/AcrD/AcrF family 7 1035 0.0 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS18690 eaffddc7a895c6ba91b1359721f830a4 1064 SUPERFAMILY SSF82866 299 505 2.22E-37 T 29-03-2018 CDC59_RS18690 eaffddc7a895c6ba91b1359721f830a4 1064 Gene3D G3DSA:3.30.70.1430 42 135 2.9E-24 T 29-03-2018 CDC59_RS18690 eaffddc7a895c6ba91b1359721f830a4 1064 Gene3D G3DSA:3.30.70.1430 568 678 3.5E-10 T 29-03-2018 CDC59_RS16815 89e9dbde0e5bc16a187eaa2d42ef14b0 255 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 16 195 1.3E-4 T 29-03-2018 CDC59_RS16815 89e9dbde0e5bc16a187eaa2d42ef14b0 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 24 254 5.5E-67 T 29-03-2018 CDC59_RS16815 89e9dbde0e5bc16a187eaa2d42ef14b0 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 151 179 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CDC59_RS16815 89e9dbde0e5bc16a187eaa2d42ef14b0 255 SUPERFAMILY SSF51735 16 254 2.58E-87 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS16815 89e9dbde0e5bc16a187eaa2d42ef14b0 255 Gene3D G3DSA:3.40.50.720 53 255 1.3E-71 T 29-03-2018 CDC59_RS16815 89e9dbde0e5bc16a187eaa2d42ef14b0 255 Gene3D G3DSA:3.40.50.720 8 52 3.8E-10 T 29-03-2018 CDC59_RS16815 89e9dbde0e5bc16a187eaa2d42ef14b0 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 9.9E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS16815 89e9dbde0e5bc16a187eaa2d42ef14b0 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 9.9E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS16815 89e9dbde0e5bc16a187eaa2d42ef14b0 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 9.9E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS16815 89e9dbde0e5bc16a187eaa2d42ef14b0 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 9.9E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS16815 89e9dbde0e5bc16a187eaa2d42ef14b0 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 9.9E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS16815 89e9dbde0e5bc16a187eaa2d42ef14b0 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 9.9E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS16815 89e9dbde0e5bc16a187eaa2d42ef14b0 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 92 103 1.2E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS16815 89e9dbde0e5bc16a187eaa2d42ef14b0 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 152 1.2E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS16815 89e9dbde0e5bc16a187eaa2d42ef14b0 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 164 183 1.2E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS18130 8df93033194589ae66b8e24d11fd770f 173 Pfam PF05229 Spore Coat Protein U domain 37 170 2.4E-36 T 29-03-2018 IPR007893 Spore coat protein U CDC59_RS18130 8df93033194589ae66b8e24d11fd770f 173 SMART SM00972 112 170 3.9E-22 T 29-03-2018 IPR007893 Spore coat protein U CDC59_RS18130 8df93033194589ae66b8e24d11fd770f 173 SUPERFAMILY SSF49401 50 173 3.88E-5 T 29-03-2018 IPR008966 Adhesion domain CDC59_RS18130 8df93033194589ae66b8e24d11fd770f 173 Gene3D G3DSA:2.60.40.1090 31 173 4.6E-4 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 CDC59_RS16185 57f0cd96aa9cf1a905ea463e5382188b 203 PRINTS PR00598 Bacterial regulatory protein MarR family signature 125 141 2.6E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS16185 57f0cd96aa9cf1a905ea463e5382188b 203 PRINTS PR00598 Bacterial regulatory protein MarR family signature 106 121 2.6E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS16185 57f0cd96aa9cf1a905ea463e5382188b 203 SUPERFAMILY SSF46785 39 177 3.02E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS16185 57f0cd96aa9cf1a905ea463e5382188b 203 ProSitePatterns PS01117 MarR-type HTH domain signature. 104 138 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CDC59_RS16185 57f0cd96aa9cf1a905ea463e5382188b 203 Gene3D G3DSA:1.10.10.10 27 186 9.7E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS16185 57f0cd96aa9cf1a905ea463e5382188b 203 SMART SM00347 64 165 4.0E-23 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS16185 57f0cd96aa9cf1a905ea463e5382188b 203 Pfam PF01047 MarR family 72 129 1.8E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS02905 c2a419c1af2afa8352f4d0818ba634ea 345 Pfam PF02885 Glycosyl transferase family, helical bundle domain 7 68 1.3E-12 T 29-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CDC59_RS02905 c2a419c1af2afa8352f4d0818ba634ea 345 Gene3D G3DSA:3.40.1030.10 75 345 4.1E-105 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CDC59_RS02905 c2a419c1af2afa8352f4d0818ba634ea 345 Gene3D G3DSA:1.20.970.10 1 72 8.7E-17 T 29-03-2018 CDC59_RS02905 c2a419c1af2afa8352f4d0818ba634ea 345 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 10 338 4.1E-121 T 29-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 CDC59_RS02905 c2a419c1af2afa8352f4d0818ba634ea 345 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 7 339 36.858 T 29-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 CDC59_RS02905 c2a419c1af2afa8352f4d0818ba634ea 345 SUPERFAMILY SSF52418 79 343 2.88E-98 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CDC59_RS02905 c2a419c1af2afa8352f4d0818ba634ea 345 SUPERFAMILY SSF47648 4 71 9.55E-17 T 29-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CDC59_RS02905 c2a419c1af2afa8352f4d0818ba634ea 345 Pfam PF00591 Glycosyl transferase family, a/b domain 79 329 6.5E-92 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CDC59_RS10305 26a178c8b5ae7eb7f6b31fb5d1684f19 459 Gene3D G3DSA:3.80.30.20 148 394 3.8E-45 T 29-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe CDC59_RS10305 26a178c8b5ae7eb7f6b31fb5d1684f19 459 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 16 457 9.5E-96 T 29-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 CDC59_RS10305 26a178c8b5ae7eb7f6b31fb5d1684f19 459 Pfam PF04055 Radical SAM superfamily 157 338 6.5E-30 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CDC59_RS10305 26a178c8b5ae7eb7f6b31fb5d1684f19 459 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 15 459 60.055 T 29-03-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 CDC59_RS10305 26a178c8b5ae7eb7f6b31fb5d1684f19 459 Gene3D G3DSA:2.40.50.140 395 459 7.7E-21 T 29-03-2018 CDC59_RS10305 26a178c8b5ae7eb7f6b31fb5d1684f19 459 Pfam PF00919 Uncharacterized protein family UPF0004 16 95 1.1E-18 T 29-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 CDC59_RS10305 26a178c8b5ae7eb7f6b31fb5d1684f19 459 SMART SM00729 151 380 1.7E-50 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CDC59_RS10305 26a178c8b5ae7eb7f6b31fb5d1684f19 459 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 155 175 - T 29-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 CDC59_RS10305 26a178c8b5ae7eb7f6b31fb5d1684f19 459 SUPERFAMILY SSF102114 128 384 4.45E-50 T 29-03-2018 CDC59_RS10305 26a178c8b5ae7eb7f6b31fb5d1684f19 459 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 16 457 2.3E-168 T 29-03-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 CDC59_RS13525 45acfb29f053d850625402ba1b75b9a1 835 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 363 507 4.9E-19 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CDC59_RS13525 45acfb29f053d850625402ba1b75b9a1 835 SUPERFAMILY SSF56645 99 373 3.66E-44 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CDC59_RS13525 45acfb29f053d850625402ba1b75b9a1 835 Gene3D G3DSA:2.40.110.10 239 352 3.3E-14 T 29-03-2018 CDC59_RS13525 45acfb29f053d850625402ba1b75b9a1 835 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 140 236 4.3E-19 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CDC59_RS13525 45acfb29f053d850625402ba1b75b9a1 835 SUPERFAMILY SSF47203 363 510 1.61E-30 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CDC59_RS13525 45acfb29f053d850625402ba1b75b9a1 835 Gene3D G3DSA:1.20.140.10 353 514 1.1E-29 T 29-03-2018 CDC59_RS13525 45acfb29f053d850625402ba1b75b9a1 835 Pfam PF09317 Domain of unknown function (DUF1974) 517 807 2.9E-105 T 29-03-2018 IPR015396 Acyl-CoA dehydrogenase, C-termina, bacterial type GO:0003995|GO:0033539|GO:0055114 CDC59_RS13525 45acfb29f053d850625402ba1b75b9a1 835 Gene3D G3DSA:1.10.540.10 79 238 2.5E-32 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CDC59_RS08275 2595b9c77778b2761adb98a34f39a3d3 305 Pfam PF01418 Helix-turn-helix domain, rpiR family 31 95 2.6E-13 T 29-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CDC59_RS08275 2595b9c77778b2761adb98a34f39a3d3 305 SUPERFAMILY SSF46689 31 105 2.15E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS08275 2595b9c77778b2761adb98a34f39a3d3 305 SUPERFAMILY SSF53697 131 294 1.5E-27 T 29-03-2018 CDC59_RS08275 2595b9c77778b2761adb98a34f39a3d3 305 Gene3D G3DSA:1.10.10.10 28 139 3.4E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS08275 2595b9c77778b2761adb98a34f39a3d3 305 Gene3D G3DSA:3.40.50.10490 140 303 1.4E-27 T 29-03-2018 CDC59_RS08275 2595b9c77778b2761adb98a34f39a3d3 305 Pfam PF01380 SIS domain 163 287 1.4E-22 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CDC59_RS10760 711d31c2956e9ad7c1b41f2315793e31 562 SUPERFAMILY SSF51905 316 460 2.49E-55 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS10760 711d31c2956e9ad7c1b41f2315793e31 562 SUPERFAMILY SSF51905 13 219 2.49E-55 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS10760 711d31c2956e9ad7c1b41f2315793e31 562 SUPERFAMILY SSF54862 462 561 3.35E-28 T 29-03-2018 CDC59_RS10760 711d31c2956e9ad7c1b41f2315793e31 562 Pfam PF05187 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S 458 559 1.0E-50 T 29-03-2018 CDC59_RS10760 711d31c2956e9ad7c1b41f2315793e31 562 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 19 41 3.0E-5 T 29-03-2018 CDC59_RS10760 711d31c2956e9ad7c1b41f2315793e31 562 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 188 203 3.0E-5 T 29-03-2018 CDC59_RS10760 711d31c2956e9ad7c1b41f2315793e31 562 Pfam PF13450 NAD(P)-binding Rossmann-like domain 22 67 8.5E-7 T 29-03-2018 CDC59_RS10760 711d31c2956e9ad7c1b41f2315793e31 562 Gene3D G3DSA:3.50.50.60 2 394 6.9E-49 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS10760 711d31c2956e9ad7c1b41f2315793e31 562 SUPERFAMILY SSF54373 221 315 4.71E-37 T 29-03-2018 CDC59_RS18095 e6bbe2a4c78356e3b310782d5871e48d 372 Pfam PF02661 Fic/DOC family 118 229 3.9E-17 T 29-03-2018 IPR003812 Fido domain CDC59_RS18095 e6bbe2a4c78356e3b310782d5871e48d 372 Pfam PF13776 Domain of unknown function (DUF4172) 8 89 2.2E-31 T 29-03-2018 IPR025230 Domain of unknown function DUF4172 CDC59_RS18095 e6bbe2a4c78356e3b310782d5871e48d 372 Gene3D G3DSA:1.10.3290.10 27 287 7.6E-46 T 29-03-2018 IPR003812 Fido domain CDC59_RS18095 e6bbe2a4c78356e3b310782d5871e48d 372 Gene3D G3DSA:1.10.10.10 288 372 3.7E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS18095 e6bbe2a4c78356e3b310782d5871e48d 372 SUPERFAMILY SSF140931 102 299 4.71E-36 T 29-03-2018 IPR003812 Fido domain CDC59_RS11885 65981e089630647b3015baa92558ce6a 585 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 19 579 8.7E-255 T 29-03-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CDC59_RS11885 65981e089630647b3015baa92558ce6a 585 Gene3D G3DSA:3.40.50.970 12 206 1.4E-63 T 29-03-2018 CDC59_RS11885 65981e089630647b3015baa92558ce6a 585 Gene3D G3DSA:3.40.50.1220 207 368 1.0E-51 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CDC59_RS11885 65981e089630647b3015baa92558ce6a 585 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 408 555 2.1E-49 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CDC59_RS11885 65981e089630647b3015baa92558ce6a 585 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 19 183 4.7E-59 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CDC59_RS11885 65981e089630647b3015baa92558ce6a 585 SUPERFAMILY SSF52467 202 375 2.14E-64 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CDC59_RS11885 65981e089630647b3015baa92558ce6a 585 SUPERFAMILY SSF52518 15 198 2.08E-64 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CDC59_RS11885 65981e089630647b3015baa92558ce6a 585 SUPERFAMILY SSF52518 386 580 3.73E-68 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CDC59_RS11885 65981e089630647b3015baa92558ce6a 585 Gene3D G3DSA:3.40.50.970 369 578 8.9E-50 T 29-03-2018 CDC59_RS11885 65981e089630647b3015baa92558ce6a 585 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 209 344 1.9E-46 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CDC59_RS10550 425b7fda774561910c1b5d438b83b14b 267 SUPERFAMILY SSF52833 37 265 7.46E-59 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS10550 425b7fda774561910c1b5d438b83b14b 267 Pfam PF06764 Protein of unknown function (DUF1223) 43 249 2.8E-55 T 29-03-2018 IPR010634 Protein of unknown function DUF1223 CDC59_RS10550 425b7fda774561910c1b5d438b83b14b 267 Gene3D G3DSA:2.60.40.10 145 266 9.9E-11 T 29-03-2018 IPR013783 Immunoglobulin-like fold CDC59_RS06150 bdad4b4ebbce88e5b10b5860ff295b5a 603 Hamap MF_00974 DNA primase [dnaG]. 1 593 27.977 T 29-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 CDC59_RS06150 bdad4b4ebbce88e5b10b5860ff295b5a 603 Pfam PF01807 CHC2 zinc finger 3 97 4.4E-39 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CDC59_RS06150 bdad4b4ebbce88e5b10b5860ff295b5a 603 TIGRFAM TIGR01391 dnaG: DNA primase 2 422 7.8E-133 T 29-03-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 CDC59_RS06150 bdad4b4ebbce88e5b10b5860ff295b5a 603 Gene3D G3DSA:1.20.50.20 374 427 9.9E-15 T 29-03-2018 CDC59_RS06150 bdad4b4ebbce88e5b10b5860ff295b5a 603 SMART SM00766 463 593 1.9E-23 T 29-03-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 CDC59_RS06150 bdad4b4ebbce88e5b10b5860ff295b5a 603 Pfam PF10410 DnaB-helicase binding domain of primase 375 428 2.1E-10 T 29-03-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 CDC59_RS06150 bdad4b4ebbce88e5b10b5860ff295b5a 603 Gene3D G3DSA:3.40.1360.10 247 373 5.3E-30 T 29-03-2018 CDC59_RS06150 bdad4b4ebbce88e5b10b5860ff295b5a 603 Pfam PF08275 DNA primase catalytic core, N-terminal domain 127 257 3.0E-35 T 29-03-2018 IPR013264 DNA primase, catalytic core, N-terminal CDC59_RS06150 bdad4b4ebbce88e5b10b5860ff295b5a 603 SUPERFAMILY SSF56731 116 427 1.7E-98 T 29-03-2018 CDC59_RS06150 bdad4b4ebbce88e5b10b5860ff295b5a 603 Pfam PF08278 DNA primase DnaG DnaB-binding 465 592 2.6E-16 T 29-03-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 CDC59_RS06150 bdad4b4ebbce88e5b10b5860ff295b5a 603 Pfam PF13662 Toprim domain 267 333 1.1E-15 T 29-03-2018 IPR006171 TOPRIM domain CDC59_RS06150 bdad4b4ebbce88e5b10b5860ff295b5a 603 Gene3D G3DSA:1.10.860.10 447 599 1.8E-22 T 29-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal CDC59_RS06150 bdad4b4ebbce88e5b10b5860ff295b5a 603 Gene3D G3DSA:3.90.980.10 109 246 2.7E-39 T 29-03-2018 IPR013264 DNA primase, catalytic core, N-terminal CDC59_RS06150 bdad4b4ebbce88e5b10b5860ff295b5a 603 SUPERFAMILY SSF117023 465 594 6.54E-7 T 29-03-2018 CDC59_RS06150 bdad4b4ebbce88e5b10b5860ff295b5a 603 SUPERFAMILY SSF57783 2 97 3.74E-37 T 29-03-2018 CDC59_RS06150 bdad4b4ebbce88e5b10b5860ff295b5a 603 SMART SM00493 265 336 3.6E-14 T 29-03-2018 IPR006171 TOPRIM domain CDC59_RS06150 bdad4b4ebbce88e5b10b5860ff295b5a 603 SMART SM00400 33 87 1.7E-34 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CDC59_RS06150 bdad4b4ebbce88e5b10b5860ff295b5a 603 Gene3D G3DSA:3.90.580.10 1 99 2.2E-34 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CDC59_RS13870 daa91be5a21b2a18583e95d28f3e9428 139 Pfam PF03061 Thioesterase superfamily 33 104 9.7E-15 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CDC59_RS13870 daa91be5a21b2a18583e95d28f3e9428 139 SUPERFAMILY SSF54637 21 138 8.95E-36 T 29-03-2018 IPR029069 HotDog domain CDC59_RS13870 daa91be5a21b2a18583e95d28f3e9428 139 Gene3D G3DSA:3.10.129.10 1 139 7.0E-31 T 29-03-2018 CDC59_RS22020 21c1cae0aeb38a46978bb177250f422f 160 Pfam PF15593 Immunity protein 42 1 150 5.7E-29 T 29-03-2018 IPR028958 Immunity protein 42 CDC59_RS19450 dd9f820112549aa24f0e314319bcae17 319 SUPERFAMILY SSF56281 14 311 6.44E-59 T 29-03-2018 IPR001279 Metallo-beta-lactamase CDC59_RS19450 dd9f820112549aa24f0e314319bcae17 319 SMART SM00849 33 222 8.6E-19 T 29-03-2018 IPR001279 Metallo-beta-lactamase CDC59_RS19450 dd9f820112549aa24f0e314319bcae17 319 Gene3D G3DSA:3.60.15.10 11 244 1.9E-31 T 29-03-2018 IPR001279 Metallo-beta-lactamase CDC59_RS19450 dd9f820112549aa24f0e314319bcae17 319 Pfam PF00753 Metallo-beta-lactamase superfamily 33 221 5.8E-16 T 29-03-2018 IPR001279 Metallo-beta-lactamase CDC59_RS16240 44917e40fb507c8d1dcb75b0733af05e 272 Gene3D G3DSA:3.40.1410.10 78 238 5.7E-38 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CDC59_RS16240 44917e40fb507c8d1dcb75b0733af05e 272 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 30 44 5.6E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDC59_RS16240 44917e40fb507c8d1dcb75b0733af05e 272 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 44 60 5.6E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDC59_RS16240 44917e40fb507c8d1dcb75b0733af05e 272 SMART SM00345 12 70 7.5E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDC59_RS16240 44917e40fb507c8d1dcb75b0733af05e 272 SMART SM00866 91 230 5.3E-32 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CDC59_RS16240 44917e40fb507c8d1dcb75b0733af05e 272 SUPERFAMILY SSF46785 6 74 1.54E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS16240 44917e40fb507c8d1dcb75b0733af05e 272 Pfam PF07702 UTRA domain 93 230 3.8E-36 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CDC59_RS16240 44917e40fb507c8d1dcb75b0733af05e 272 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 70 7.0E-13 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDC59_RS16240 44917e40fb507c8d1dcb75b0733af05e 272 SUPERFAMILY SSF64288 58 237 6.91E-43 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CDC59_RS16240 44917e40fb507c8d1dcb75b0733af05e 272 Gene3D G3DSA:1.10.10.10 2 77 1.9E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS00455 a06dd0882d98a2c1b4313845b9ea2b5c 481 Pfam PF12161 HsdM N-terminal domain 6 132 3.4E-7 T 29-03-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain CDC59_RS00455 a06dd0882d98a2c1b4313845b9ea2b5c 481 SUPERFAMILY SSF53335 5 471 4.73E-98 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS00455 a06dd0882d98a2c1b4313845b9ea2b5c 481 Pfam PF02384 N-6 DNA Methylase 141 472 2.2E-48 T 29-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 CDC59_RS00455 a06dd0882d98a2c1b4313845b9ea2b5c 481 Gene3D G3DSA:3.40.50.150 160 471 6.0E-57 T 29-03-2018 CDC59_RS00455 a06dd0882d98a2c1b4313845b9ea2b5c 481 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 300 324 1.6E-19 T 29-03-2018 CDC59_RS00455 a06dd0882d98a2c1b4313845b9ea2b5c 481 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 186 200 1.6E-19 T 29-03-2018 CDC59_RS00455 a06dd0882d98a2c1b4313845b9ea2b5c 481 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 162 178 1.6E-19 T 29-03-2018 CDC59_RS00455 a06dd0882d98a2c1b4313845b9ea2b5c 481 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 270 282 1.6E-19 T 29-03-2018 CDC59_RS14540 13c977d74ab27e961616312349b154d2 89 Pfam PF00381 PTS HPr component phosphorylation site 3 82 1.2E-28 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CDC59_RS14540 13c977d74ab27e961616312349b154d2 89 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 82 9.7E-33 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CDC59_RS14540 13c977d74ab27e961616312349b154d2 89 SUPERFAMILY SSF55594 1 87 3.27E-30 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CDC59_RS14540 13c977d74ab27e961616312349b154d2 89 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 29-03-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site CDC59_RS14540 13c977d74ab27e961616312349b154d2 89 Gene3D G3DSA:3.30.1340.10 1 87 9.6E-31 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CDC59_RS14540 13c977d74ab27e961616312349b154d2 89 PRINTS PR00107 Phosphocarrier protein signature 13 29 4.8E-17 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CDC59_RS14540 13c977d74ab27e961616312349b154d2 89 PRINTS PR00107 Phosphocarrier protein signature 38 53 4.8E-17 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CDC59_RS14540 13c977d74ab27e961616312349b154d2 89 PRINTS PR00107 Phosphocarrier protein signature 53 70 4.8E-17 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CDC59_RS14540 13c977d74ab27e961616312349b154d2 89 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 29-03-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site CDC59_RS21930 6d2fd46c1fff217a2d6aac74f2e572bd 336 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 8 212 5.3E-43 T 29-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CDC59_RS21930 6d2fd46c1fff217a2d6aac74f2e572bd 336 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 8 323 8.9E-92 T 29-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CDC59_RS21105 535f59cb5fd1abb7cd35f8132710a1eb 355 PIRSF PIRSF012641 1 355 1.4E-166 T 29-03-2018 IPR031321 Uncharacterised conserved protein UCP012641, putative zinc-binding metallo-peptidase CDC59_RS21105 535f59cb5fd1abb7cd35f8132710a1eb 355 Pfam PF15887 Putative zinc-binding metallo-peptidase 104 346 5.5E-108 T 29-03-2018 IPR031321 Uncharacterised conserved protein UCP012641, putative zinc-binding metallo-peptidase CDC59_RS21105 535f59cb5fd1abb7cd35f8132710a1eb 355 Gene3D G3DSA:3.40.390.10 108 315 1.8E-17 T 29-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CDC59_RS21105 535f59cb5fd1abb7cd35f8132710a1eb 355 Pfam PF10005 zinc-ribbon domain 3 97 2.3E-30 T 29-03-2018 IPR011201 Zinc-ribbon domain, bacteria CDC59_RS00390 a56f022c0b264510e776b7b3d1c23bd0 223 TIGRFAM TIGR03003 ectoine_ehuD: ectoine/hydroxyectoine ABC transporter, permease protein EhuD 8 215 1.5E-62 T 29-03-2018 IPR014341 Ectoine/hydroxyectoine ABC transporter, permease protein EhuD CDC59_RS00390 a56f022c0b264510e776b7b3d1c23bd0 223 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 37 214 2.3E-16 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS00390 a56f022c0b264510e776b7b3d1c23bd0 223 SUPERFAMILY SSF161098 15 202 8.76E-46 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS00390 a56f022c0b264510e776b7b3d1c23bd0 223 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 14 111 2.2E-30 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CDC59_RS00390 a56f022c0b264510e776b7b3d1c23bd0 223 Gene3D G3DSA:1.10.3720.10 3 221 2.2E-42 T 29-03-2018 CDC59_RS19945 7d77ea25534e97605c4d8dc8fe7e598b 207 Gene3D G3DSA:1.10.357.10 68 202 4.2E-20 T 29-03-2018 CDC59_RS19945 7d77ea25534e97605c4d8dc8fe7e598b 207 Pfam PF14246 AefR-like transcriptional repressor, C-terminal region 143 197 1.5E-9 T 29-03-2018 CDC59_RS19945 7d77ea25534e97605c4d8dc8fe7e598b 207 ProSitePatterns PS01081 TetR-type HTH domain signature. 24 54 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CDC59_RS19945 7d77ea25534e97605c4d8dc8fe7e598b 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 58 1.2E-18 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDC59_RS19945 7d77ea25534e97605c4d8dc8fe7e598b 207 Gene3D G3DSA:1.10.10.60 1 41 8.8E-19 T 29-03-2018 CDC59_RS19945 7d77ea25534e97605c4d8dc8fe7e598b 207 SUPERFAMILY SSF46689 1 81 1.55E-19 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS19945 7d77ea25534e97605c4d8dc8fe7e598b 207 Gene3D G3DSA:1.10.260.40 42 67 4.4E-10 T 29-03-2018 CDC59_RS19945 7d77ea25534e97605c4d8dc8fe7e598b 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 3.7E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDC59_RS19945 7d77ea25534e97605c4d8dc8fe7e598b 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 3.7E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDC59_RS00295 12833b72f8b373fe5e99aab33b609aa7 341 Gene3D G3DSA:3.40.190.10 144 252 3.1E-7 T 29-03-2018 CDC59_RS00295 12833b72f8b373fe5e99aab33b609aa7 341 PIRSF PIRSF017082 10 341 1.2E-72 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CDC59_RS00295 12833b72f8b373fe5e99aab33b609aa7 341 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 64 337 2.2E-78 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CDC59_RS00295 12833b72f8b373fe5e99aab33b609aa7 341 SUPERFAMILY SSF53850 127 303 3.26E-6 T 29-03-2018 CDC59_RS00435 816e25b7ec9bfc830923454045144f6b 423 ProSitePatterns PS00216 Sugar transport proteins signature 1. 270 287 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CDC59_RS00435 816e25b7ec9bfc830923454045144f6b 423 SUPERFAMILY SSF103473 8 399 4.97E-64 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS00435 816e25b7ec9bfc830923454045144f6b 423 Gene3D G3DSA:1.20.1250.20 4 198 1.9E-32 T 29-03-2018 CDC59_RS00435 816e25b7ec9bfc830923454045144f6b 423 Pfam PF07690 Major Facilitator Superfamily 16 235 8.8E-30 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDC59_RS00435 816e25b7ec9bfc830923454045144f6b 423 Gene3D G3DSA:1.20.1250.20 201 398 9.6E-21 T 29-03-2018 CDC59_RS03140 a95ba28602c94ec862f8908535f11993 331 PIRSF PIRSF039102 15 60 2.1E-7 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDC59_RS03140 a95ba28602c94ec862f8908535f11993 331 PIRSF PIRSF039102 56 326 3.7E-85 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDC59_RS03140 a95ba28602c94ec862f8908535f11993 331 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 19 318 3.0E-97 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDC59_RS03140 a95ba28602c94ec862f8908535f11993 331 Pfam PF07478 D-ala D-ala ligase C-terminus 118 314 1.7E-59 T 29-03-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDC59_RS03140 a95ba28602c94ec862f8908535f11993 331 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 260 289 - T 29-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDC59_RS03140 a95ba28602c94ec862f8908535f11993 331 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 78 89 - T 29-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDC59_RS03140 a95ba28602c94ec862f8908535f11993 331 Pfam PF01820 D-ala D-ala ligase N-terminus 19 101 4.6E-16 T 29-03-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDC59_RS03140 a95ba28602c94ec862f8908535f11993 331 Gene3D G3DSA:3.30.470.20 181 328 6.8E-38 T 29-03-2018 CDC59_RS03140 a95ba28602c94ec862f8908535f11993 331 Gene3D G3DSA:3.40.50.20 12 112 1.3E-32 T 29-03-2018 CDC59_RS03140 a95ba28602c94ec862f8908535f11993 331 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 18 319 34.852 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDC59_RS03140 a95ba28602c94ec862f8908535f11993 331 SUPERFAMILY SSF56059 111 322 3.36E-58 T 29-03-2018 CDC59_RS03140 a95ba28602c94ec862f8908535f11993 331 SUPERFAMILY SSF52440 19 111 2.69E-29 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CDC59_RS03140 a95ba28602c94ec862f8908535f11993 331 Gene3D G3DSA:3.30.1490.20 113 180 2.6E-22 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CDC59_RS16380 5a61f4d9df6e77840eb462cf6573877b 650 Pfam PF02954 Bacterial regulatory protein, Fis family 614 648 8.1E-9 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CDC59_RS16380 5a61f4d9df6e77840eb462cf6573877b 650 SMART SM00382 348 493 2.2E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS16380 5a61f4d9df6e77840eb462cf6573877b 650 SUPERFAMILY SSF46689 551 648 1.25E-6 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS16380 5a61f4d9df6e77840eb462cf6573877b 650 Gene3D G3DSA:3.40.50.300 336 501 1.2E-25 T 29-03-2018 CDC59_RS16380 5a61f4d9df6e77840eb462cf6573877b 650 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 352 365 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CDC59_RS16380 5a61f4d9df6e77840eb462cf6573877b 650 SMART SM00091 203 268 0.0016 T 29-03-2018 IPR000014 PAS domain CDC59_RS16380 5a61f4d9df6e77840eb462cf6573877b 650 Gene3D G3DSA:3.40.50.2300 2 96 1.6E-18 T 29-03-2018 CDC59_RS16380 5a61f4d9df6e77840eb462cf6573877b 650 SUPERFAMILY SSF159800 11 194 9.94E-50 T 29-03-2018 CDC59_RS16380 5a61f4d9df6e77840eb462cf6573877b 650 SUPERFAMILY SSF52540 327 568 1.25E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS16380 5a61f4d9df6e77840eb462cf6573877b 650 Pfam PF06506 Propionate catabolism activator 33 198 1.4E-48 T 29-03-2018 IPR010524 Signal transduction response regulator, propionate catabolism activator, N-terminal GO:0000156|GO:0000160|GO:0003677|GO:0005524 CDC59_RS16380 5a61f4d9df6e77840eb462cf6573877b 650 SUPERFAMILY SSF55785 192 266 1.74E-10 T 29-03-2018 IPR000014 PAS domain CDC59_RS16380 5a61f4d9df6e77840eb462cf6573877b 650 TIGRFAM TIGR02329 propionate_PrpR: propionate catabolism operon regulatory protein PrpR 10 649 3.2E-263 T 29-03-2018 IPR012704 Signal transduction response regulator, propionate catabolism, transcriptional regulator PrpR GO:0000156|GO:0000160|GO:0003677|GO:0005524|GO:0005737|GO:0019629 CDC59_RS16380 5a61f4d9df6e77840eb462cf6573877b 650 Gene3D G3DSA:3.30.450.20 189 335 2.2E-13 T 29-03-2018 CDC59_RS16380 5a61f4d9df6e77840eb462cf6573877b 650 Gene3D G3DSA:1.10.10.60 599 648 3.1E-10 T 29-03-2018 CDC59_RS16380 5a61f4d9df6e77840eb462cf6573877b 650 Gene3D G3DSA:3.40.50.10660 97 176 2.0E-21 T 29-03-2018 CDC59_RS16380 5a61f4d9df6e77840eb462cf6573877b 650 Pfam PF00989 PAS fold 204 250 2.8E-5 T 29-03-2018 IPR013767 PAS fold GO:0006355 CDC59_RS16380 5a61f4d9df6e77840eb462cf6573877b 650 Pfam PF00158 Sigma-54 interaction domain 328 495 2.5E-67 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CDC59_RS16380 5a61f4d9df6e77840eb462cf6573877b 650 Gene3D G3DSA:1.10.8.60 502 589 2.9E-13 T 29-03-2018 CDC59_RS12465 3d65a93c9cc9b1781ab2c7ab08f1d529 554 PRINTS PR00397 Sirohaem Fe-binding site signature 457 475 4.2E-5 T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CDC59_RS12465 3d65a93c9cc9b1781ab2c7ab08f1d529 554 PRINTS PR00397 Sirohaem Fe-binding site signature 411 429 4.2E-5 T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CDC59_RS12465 3d65a93c9cc9b1781ab2c7ab08f1d529 554 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 328 400 2.7E-15 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CDC59_RS12465 3d65a93c9cc9b1781ab2c7ab08f1d529 554 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 50 110 2.2E-14 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CDC59_RS12465 3d65a93c9cc9b1781ab2c7ab08f1d529 554 SUPERFAMILY SSF55124 315 422 7.03E-26 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CDC59_RS12465 3d65a93c9cc9b1781ab2c7ab08f1d529 554 SUPERFAMILY SSF55124 252 276 7.03E-26 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CDC59_RS12465 3d65a93c9cc9b1781ab2c7ab08f1d529 554 Gene3D G3DSA:3.90.480.10 49 211 1.1E-18 T 29-03-2018 CDC59_RS12465 3d65a93c9cc9b1781ab2c7ab08f1d529 554 Gene3D G3DSA:3.90.480.10 215 404 6.7E-31 T 29-03-2018 CDC59_RS12465 3d65a93c9cc9b1781ab2c7ab08f1d529 554 SUPERFAMILY SSF56014 410 550 1.57E-39 T 29-03-2018 CDC59_RS12465 3d65a93c9cc9b1781ab2c7ab08f1d529 554 SUPERFAMILY SSF55124 1 126 1.16E-29 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CDC59_RS12465 3d65a93c9cc9b1781ab2c7ab08f1d529 554 SUPERFAMILY SSF56014 120 287 3.27E-44 T 29-03-2018 CDC59_RS12465 3d65a93c9cc9b1781ab2c7ab08f1d529 554 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 412 548 1.8E-11 T 29-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CDC59_RS12465 3d65a93c9cc9b1781ab2c7ab08f1d529 554 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 119 273 1.6E-39 T 29-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CDC59_RS12465 3d65a93c9cc9b1781ab2c7ab08f1d529 554 Gene3D G3DSA:3.30.413.10 405 553 1.8E-32 T 29-03-2018 CDC59_RS12955 e7f4fa2283c04dd9364ef7f0a3fdfe7b 299 SUPERFAMILY SSF53850 90 296 1.78E-42 T 29-03-2018 CDC59_RS12955 e7f4fa2283c04dd9364ef7f0a3fdfe7b 299 Gene3D G3DSA:1.10.10.10 1 85 1.5E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS12955 e7f4fa2283c04dd9364ef7f0a3fdfe7b 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 8.2E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS12955 e7f4fa2283c04dd9364ef7f0a3fdfe7b 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 8.2E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS12955 e7f4fa2283c04dd9364ef7f0a3fdfe7b 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 8.2E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS12955 e7f4fa2283c04dd9364ef7f0a3fdfe7b 299 Gene3D G3DSA:3.40.190.10 179 270 1.6E-25 T 29-03-2018 CDC59_RS12955 e7f4fa2283c04dd9364ef7f0a3fdfe7b 299 SUPERFAMILY SSF46785 3 111 1.36E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS12955 e7f4fa2283c04dd9364ef7f0a3fdfe7b 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 1.7E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS12955 e7f4fa2283c04dd9364ef7f0a3fdfe7b 299 Gene3D G3DSA:3.40.190.10 89 178 2.2E-22 T 29-03-2018 CDC59_RS12955 e7f4fa2283c04dd9364ef7f0a3fdfe7b 299 Pfam PF03466 LysR substrate binding domain 89 294 2.7E-42 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS02575 19182cd8618ce35e068eae08c724bf0c 442 PIRSF PIRSF000099 3 439 5.1E-156 T 29-03-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CDC59_RS02575 19182cd8618ce35e068eae08c724bf0c 442 Gene3D G3DSA:3.40.50.1980 235 380 5.7E-69 T 29-03-2018 CDC59_RS02575 19182cd8618ce35e068eae08c724bf0c 442 SUPERFAMILY SSF53720 31 436 5.3E-86 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CDC59_RS02575 19182cd8618ce35e068eae08c724bf0c 442 Pfam PF00815 Histidinol dehydrogenase 28 436 2.0E-166 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CDC59_RS02575 19182cd8618ce35e068eae08c724bf0c 442 PRINTS PR00083 Histidinol dehydrogenase signature 329 354 2.8E-82 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CDC59_RS02575 19182cd8618ce35e068eae08c724bf0c 442 PRINTS PR00083 Histidinol dehydrogenase signature 209 234 2.8E-82 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CDC59_RS02575 19182cd8618ce35e068eae08c724bf0c 442 PRINTS PR00083 Histidinol dehydrogenase signature 260 279 2.8E-82 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CDC59_RS02575 19182cd8618ce35e068eae08c724bf0c 442 PRINTS PR00083 Histidinol dehydrogenase signature 37 61 2.8E-82 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CDC59_RS02575 19182cd8618ce35e068eae08c724bf0c 442 PRINTS PR00083 Histidinol dehydrogenase signature 145 171 2.8E-82 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CDC59_RS02575 19182cd8618ce35e068eae08c724bf0c 442 PRINTS PR00083 Histidinol dehydrogenase signature 179 205 2.8E-82 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CDC59_RS02575 19182cd8618ce35e068eae08c724bf0c 442 PRINTS PR00083 Histidinol dehydrogenase signature 238 259 2.8E-82 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CDC59_RS02575 19182cd8618ce35e068eae08c724bf0c 442 PRINTS PR00083 Histidinol dehydrogenase signature 370 388 2.8E-82 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CDC59_RS02575 19182cd8618ce35e068eae08c724bf0c 442 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 238 270 - T 29-03-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 CDC59_RS02575 19182cd8618ce35e068eae08c724bf0c 442 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 3 436 41.735 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CDC59_RS02575 19182cd8618ce35e068eae08c724bf0c 442 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 38 435 4.1E-158 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CDC59_RS02575 19182cd8618ce35e068eae08c724bf0c 442 Gene3D G3DSA:3.40.50.1980 30 234 6.9E-83 T 29-03-2018 CDC59_RS08890 d52c365994bde7e364619182fa4cd071 414 SMART SM00387 279 378 1.0E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS08890 d52c365994bde7e364619182fa4cd071 414 Pfam PF06580 Histidine kinase 185 264 2.6E-20 T 29-03-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 CDC59_RS08890 d52c365994bde7e364619182fa4cd071 414 Gene3D G3DSA:3.30.565.10 167 377 5.0E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS08890 d52c365994bde7e364619182fa4cd071 414 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 285 377 1.2E-7 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS08890 d52c365994bde7e364619182fa4cd071 414 SUPERFAMILY SSF55874 242 376 5.76E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS08890 d52c365994bde7e364619182fa4cd071 414 PRINTS PR00344 Bacterial sensor protein C-terminal signature 316 330 8.8E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS08890 d52c365994bde7e364619182fa4cd071 414 PRINTS PR00344 Bacterial sensor protein C-terminal signature 362 375 8.8E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS08890 d52c365994bde7e364619182fa4cd071 414 PRINTS PR00344 Bacterial sensor protein C-terminal signature 335 353 8.8E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS13235 d161a5a6c5245c2d3d02273bf5edd53e 405 Pfam PF11871 Domain of unknown function (DUF3391) 2 131 3.2E-31 T 29-03-2018 IPR021812 Protein of unknown function DUF3391 CDC59_RS13235 d161a5a6c5245c2d3d02273bf5edd53e 405 Gene3D G3DSA:1.10.3210.10 95 326 2.1E-38 T 29-03-2018 CDC59_RS13235 d161a5a6c5245c2d3d02273bf5edd53e 405 Pfam PF13487 HD domain 215 276 3.8E-10 T 29-03-2018 CDC59_RS13235 d161a5a6c5245c2d3d02273bf5edd53e 405 SUPERFAMILY SSF109604 156 323 2.9E-29 T 29-03-2018 CDC59_RS13235 d161a5a6c5245c2d3d02273bf5edd53e 405 SMART SM00471 159 295 6.6E-6 T 29-03-2018 IPR003607 HD/PDEase domain CDC59_RS05955 c7f4c8c899d4124696c062895a557d0b 263 Gene3D G3DSA:1.10.10.10 16 75 1.1E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS05955 c7f4c8c899d4124696c062895a557d0b 263 SMART SM00346 16 104 8.3E-26 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CDC59_RS05955 c7f4c8c899d4124696c062895a557d0b 263 Pfam PF09339 IclR helix-turn-helix domain 20 67 9.3E-14 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CDC59_RS05955 c7f4c8c899d4124696c062895a557d0b 263 TIGRFAM TIGR02431 pcaR_pcaU: beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family 13 258 2.7E-103 T 29-03-2018 IPR012794 Beta-ketoadipate transcriptional regulator, PcaR/PcaU/PobR GO:0003677|GO:0045893|GO:0046278 CDC59_RS05955 c7f4c8c899d4124696c062895a557d0b 263 Gene3D G3DSA:3.30.450.40 80 263 1.2E-51 T 29-03-2018 IPR029016 GAF domain-like CDC59_RS05955 c7f4c8c899d4124696c062895a557d0b 263 Pfam PF01614 Bacterial transcriptional regulator 134 257 5.0E-33 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CDC59_RS05955 c7f4c8c899d4124696c062895a557d0b 263 SUPERFAMILY SSF55781 81 258 2.03E-49 T 29-03-2018 IPR029016 GAF domain-like CDC59_RS05955 c7f4c8c899d4124696c062895a557d0b 263 SUPERFAMILY SSF46785 16 88 1.79E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS19075 18bd6f6b9e829783ab1be0ccd6b2fcaf 368 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 6 198 5.8E-42 T 29-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CDC59_RS19075 18bd6f6b9e829783ab1be0ccd6b2fcaf 368 SUPERFAMILY SSF52540 3 199 9.36E-25 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS19075 18bd6f6b9e829783ab1be0ccd6b2fcaf 368 SUPERFAMILY SSF90002 276 361 1.44E-7 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CDC59_RS19075 18bd6f6b9e829783ab1be0ccd6b2fcaf 368 SMART SM00833 275 363 1.9E-6 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CDC59_RS19075 18bd6f6b9e829783ab1be0ccd6b2fcaf 368 Gene3D G3DSA:3.40.50.300 2 217 3.7E-34 T 29-03-2018 CDC59_RS19075 18bd6f6b9e829783ab1be0ccd6b2fcaf 368 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 276 361 7.1E-11 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CDC59_RS19075 18bd6f6b9e829783ab1be0ccd6b2fcaf 368 Gene3D G3DSA:3.30.1220.10 250 364 2.3E-10 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CDC59_RS23495 0555182cf73e6a0b73b08d1c0bc39d81 467 Gene3D G3DSA:3.40.50.150 173 449 1.3E-29 T 29-03-2018 CDC59_RS23495 0555182cf73e6a0b73b08d1c0bc39d81 467 SUPERFAMILY SSF53335 166 444 4.63E-42 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS23495 0555182cf73e6a0b73b08d1c0bc39d81 467 Gene3D G3DSA:3.90.1530.10 2 92 1.4E-10 T 29-03-2018 CDC59_RS23495 0555182cf73e6a0b73b08d1c0bc39d81 467 Pfam PF02195 ParB-like nuclease domain 8 75 2.0E-8 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CDC59_RS23495 0555182cf73e6a0b73b08d1c0bc39d81 467 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 415 435 6.4E-14 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CDC59_RS23495 0555182cf73e6a0b73b08d1c0bc39d81 467 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 373 390 6.4E-14 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CDC59_RS23495 0555182cf73e6a0b73b08d1c0bc39d81 467 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 392 410 6.4E-14 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CDC59_RS23495 0555182cf73e6a0b73b08d1c0bc39d81 467 SMART SM00470 5 91 7.7E-6 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CDC59_RS23495 0555182cf73e6a0b73b08d1c0bc39d81 467 SUPERFAMILY SSF110849 3 132 2.62E-21 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CDC59_RS23495 0555182cf73e6a0b73b08d1c0bc39d81 467 PIRSF PIRSF036758 311 454 2.2E-20 T 29-03-2018 IPR015840 DNA methyase, ParB domain-containing CDC59_RS23495 0555182cf73e6a0b73b08d1c0bc39d81 467 PIRSF PIRSF036758 2 216 2.9E-47 T 29-03-2018 IPR015840 DNA methyase, ParB domain-containing CDC59_RS23495 0555182cf73e6a0b73b08d1c0bc39d81 467 Pfam PF01555 DNA methylase 268 430 8.6E-18 T 29-03-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 CDC59_RS07395 5c91c2ccf6b881173612ef75bdf93847 350 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 29 314 4.7E-70 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CDC59_RS07395 5c91c2ccf6b881173612ef75bdf93847 350 SUPERFAMILY SSF51445 13 303 2.74E-75 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CDC59_RS07395 5c91c2ccf6b881173612ef75bdf93847 350 Gene3D G3DSA:3.20.20.300 12 332 1.5E-73 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CDC59_RS07395 5c91c2ccf6b881173612ef75bdf93847 350 Hamap MF_00364 Beta-hexosaminidase [nagZ]. 13 348 49.388 T 29-03-2018 IPR022956 Beta-hexosaminidase, bacterial GO:0004563 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 CDC59_RS07145 eaebf87ca94c6e6764048d0b4da4ef5e 405 Gene3D G3DSA:3.40.640.10 16 263 1.2E-64 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDC59_RS07145 eaebf87ca94c6e6764048d0b4da4ef5e 405 PIRSF PIRSF005572 5 385 1.7E-134 T 29-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CDC59_RS07145 eaebf87ca94c6e6764048d0b4da4ef5e 405 Gene3D G3DSA:3.90.1150.10 270 385 9.3E-39 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS07145 eaebf87ca94c6e6764048d0b4da4ef5e 405 SUPERFAMILY SSF53383 8 392 1.36E-111 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS07145 eaebf87ca94c6e6764048d0b4da4ef5e 405 Hamap MF_00331 Cysteine desulfurase IscS [iscS]. 4 396 54.855 T 29-03-2018 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250|Reactome: R-HSA-1362409|Reactome: R-HSA-947581 CDC59_RS07145 eaebf87ca94c6e6764048d0b4da4ef5e 405 Pfam PF00266 Aminotransferase class-V 8 370 4.6E-87 T 29-03-2018 IPR000192 Aminotransferase class V domain CDC59_RS07145 eaebf87ca94c6e6764048d0b4da4ef5e 405 TIGRFAM TIGR02006 IscS: cysteine desulfurase IscS 6 405 2.2E-228 T 29-03-2018 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250|Reactome: R-HSA-1362409|Reactome: R-HSA-947581 CDC59_RS07145 eaebf87ca94c6e6764048d0b4da4ef5e 405 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 198 217 - T 29-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CDC59_RS02015 8121f4efa0040e634a4ba5a1d9116f12 208 Pfam PF07209 Protein of unknown function (DUF1415) 30 195 7.4E-61 T 29-03-2018 IPR009858 Protein of unknown function DUF1415 CDC59_RS16745 e9c6b4c685dda2bc61390a84aa7a32e7 711 Pfam PF14883 Hypothetical glycosyl hydrolase family 13 317 643 8.0E-149 T 29-03-2018 IPR032772 Poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB, C-terminal CDC59_RS16745 e9c6b4c685dda2bc61390a84aa7a32e7 711 Gene3D G3DSA:3.20.20.370 61 491 2.3E-44 T 29-03-2018 CDC59_RS16745 e9c6b4c685dda2bc61390a84aa7a32e7 711 TIGRFAM TIGR03938 deacetyl_PgaB: poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB 36 664 4.7E-273 T 29-03-2018 IPR023854 Poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB GO:0016810|GO:0042710 CDC59_RS16745 e9c6b4c685dda2bc61390a84aa7a32e7 711 Pfam PF01522 Polysaccharide deacetylase 94 263 5.7E-25 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CDC59_RS16745 e9c6b4c685dda2bc61390a84aa7a32e7 711 SUPERFAMILY SSF88713 58 189 3.34E-34 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CDC59_RS16745 e9c6b4c685dda2bc61390a84aa7a32e7 711 SUPERFAMILY SSF88713 217 297 3.34E-34 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CDC59_RS17400 e4ac4959a3c2514b2a6eed02c4bdb0c3 763 Pfam PF05593 RHS Repeat 229 267 3.7E-6 T 29-03-2018 IPR031325 RHS repeat CDC59_RS17400 e4ac4959a3c2514b2a6eed02c4bdb0c3 763 Pfam PF05593 RHS Repeat 125 161 5.8E-11 T 29-03-2018 IPR031325 RHS repeat CDC59_RS17400 e4ac4959a3c2514b2a6eed02c4bdb0c3 763 Pfam PF05593 RHS Repeat 35 66 4.8E-11 T 29-03-2018 IPR031325 RHS repeat CDC59_RS17400 e4ac4959a3c2514b2a6eed02c4bdb0c3 763 Pfam PF05593 RHS Repeat 177 212 6.4E-6 T 29-03-2018 IPR031325 RHS repeat CDC59_RS17400 e4ac4959a3c2514b2a6eed02c4bdb0c3 763 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 125 153 1.3E-7 T 29-03-2018 IPR006530 YD repeat CDC59_RS17400 e4ac4959a3c2514b2a6eed02c4bdb0c3 763 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 358 391 0.001 T 29-03-2018 IPR006530 YD repeat CDC59_RS17400 e4ac4959a3c2514b2a6eed02c4bdb0c3 763 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 116 144 9.8E-5 T 29-03-2018 IPR006530 YD repeat CDC59_RS17400 e4ac4959a3c2514b2a6eed02c4bdb0c3 763 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 35 63 6.3E-7 T 29-03-2018 IPR006530 YD repeat CDC59_RS17400 e4ac4959a3c2514b2a6eed02c4bdb0c3 763 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 176 206 1.0E-5 T 29-03-2018 IPR006530 YD repeat CDC59_RS17400 e4ac4959a3c2514b2a6eed02c4bdb0c3 763 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 434 462 0.0017 T 29-03-2018 IPR006530 YD repeat CDC59_RS17400 e4ac4959a3c2514b2a6eed02c4bdb0c3 763 Pfam PF10908 Protein of unknown function (DUF2778) 661 735 2.9E-7 T 29-03-2018 IPR021225 Protein of unknown function DUF2778 CDC59_RS17400 e4ac4959a3c2514b2a6eed02c4bdb0c3 763 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 543 623 2.3E-20 T 29-03-2018 IPR022385 Rhs repeat-associated core GO:0097264 CDC59_RS15745 c005d0d7d41c07dd4bb497118beabcef 813 SMART SM00388 570 642 8.2E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS15745 c005d0d7d41c07dd4bb497118beabcef 813 Gene3D G3DSA:3.30.450.20 422 565 7.2E-17 T 29-03-2018 CDC59_RS15745 c005d0d7d41c07dd4bb497118beabcef 813 Gene3D G3DSA:3.30.450.20 130 346 0.25 T 29-03-2018 CDC59_RS15745 c005d0d7d41c07dd4bb497118beabcef 813 SMART SM00304 370 422 5.0E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CDC59_RS15745 c005d0d7d41c07dd4bb497118beabcef 813 Gene3D G3DSA:3.30.565.10 642 807 4.6E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS15745 c005d0d7d41c07dd4bb497118beabcef 813 PIRSF PIRSF037532 2 255 3.4E-40 T 29-03-2018 IPR017232 Signal transduction histidine kinase, nitrogen fixation and metabolism regulator CDC59_RS15745 c005d0d7d41c07dd4bb497118beabcef 813 PIRSF PIRSF037532 286 813 1.6E-178 T 29-03-2018 IPR017232 Signal transduction histidine kinase, nitrogen fixation and metabolism regulator CDC59_RS15745 c005d0d7d41c07dd4bb497118beabcef 813 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 686 801 3.6E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS15745 c005d0d7d41c07dd4bb497118beabcef 813 SUPERFAMILY SSF55874 631 796 1.44E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS15745 c005d0d7d41c07dd4bb497118beabcef 813 Pfam PF00512 His Kinase A (phospho-acceptor) domain 571 638 5.1E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS15745 c005d0d7d41c07dd4bb497118beabcef 813 SUPERFAMILY SSF55785 426 560 9.9E-10 T 29-03-2018 IPR000014 PAS domain CDC59_RS15745 c005d0d7d41c07dd4bb497118beabcef 813 SUPERFAMILY SSF47384 567 639 7.26E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS15745 c005d0d7d41c07dd4bb497118beabcef 813 Pfam PF00672 HAMP domain 372 418 2.9E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CDC59_RS15745 c005d0d7d41c07dd4bb497118beabcef 813 PRINTS PR00344 Bacterial sensor protein C-terminal signature 739 753 3.0E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS15745 c005d0d7d41c07dd4bb497118beabcef 813 PRINTS PR00344 Bacterial sensor protein C-terminal signature 757 767 3.0E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS15745 c005d0d7d41c07dd4bb497118beabcef 813 PRINTS PR00344 Bacterial sensor protein C-terminal signature 768 786 3.0E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS15745 c005d0d7d41c07dd4bb497118beabcef 813 Pfam PF08448 PAS fold 442 561 1.2E-5 T 29-03-2018 IPR013656 PAS fold-4 CDC59_RS15745 c005d0d7d41c07dd4bb497118beabcef 813 SUPERFAMILY SSF158472 372 419 1.12E-8 T 29-03-2018 CDC59_RS15745 c005d0d7d41c07dd4bb497118beabcef 813 Gene3D G3DSA:1.10.287.130 566 638 6.1E-11 T 29-03-2018 CDC59_RS15745 c005d0d7d41c07dd4bb497118beabcef 813 SMART SM00387 686 813 5.7E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS19820 f2eac35a19f969a02b7edff76ba3c0ab 311 SMART SM00859 6 107 1.2E-14 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CDC59_RS19820 f2eac35a19f969a02b7edff76ba3c0ab 311 SUPERFAMILY SSF51735 7 140 4.67E-30 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS19820 f2eac35a19f969a02b7edff76ba3c0ab 311 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 45 101 3.2E-12 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CDC59_RS19820 f2eac35a19f969a02b7edff76ba3c0ab 311 Gene3D G3DSA:3.30.360.10 126 289 7.9E-45 T 29-03-2018 CDC59_RS19820 f2eac35a19f969a02b7edff76ba3c0ab 311 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 113 129 - T 29-03-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CDC59_RS19820 f2eac35a19f969a02b7edff76ba3c0ab 311 Hamap MF_01110 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 3 308 50.238 T 29-03-2018 IPR010136 N-acetyl-gamma-glutamyl-phosphate reductase, type 2 GO:0003942|GO:0005737|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CDC59_RS19820 f2eac35a19f969a02b7edff76ba3c0ab 311 Gene3D G3DSA:3.40.50.720 12 125 4.3E-20 T 29-03-2018 CDC59_RS19820 f2eac35a19f969a02b7edff76ba3c0ab 311 TIGRFAM TIGR01851 argC_other: N-acetyl-gamma-glutamyl-phosphate reductase 5 306 2.4E-117 T 29-03-2018 IPR010136 N-acetyl-gamma-glutamyl-phosphate reductase, type 2 GO:0003942|GO:0005737|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CDC59_RS19820 f2eac35a19f969a02b7edff76ba3c0ab 311 SUPERFAMILY SSF55347 118 289 2.75E-37 T 29-03-2018 CDC59_RS09035 dbe3f95d816eb9dacdf1abc33bbd869a 341 Pfam PF03576 Peptidase family S58 17 333 1.0E-108 T 29-03-2018 IPR005321 Peptidase S58, DmpA CDC59_RS09035 dbe3f95d816eb9dacdf1abc33bbd869a 341 SUPERFAMILY SSF56266 11 334 1.18E-100 T 29-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CDC59_RS09035 dbe3f95d816eb9dacdf1abc33bbd869a 341 Gene3D G3DSA:3.60.70.12 2 340 9.4E-102 T 29-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CDC59_RS08500 88affa543db0ca3d349e7339ccc0283e 485 SUPERFAMILY SSF81442 14 471 1.28E-127 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS08500 88affa543db0ca3d349e7339ccc0283e 485 TIGRFAM TIGR00780 ccoN: cytochrome c oxidase, cbb3-type, subunit I 12 475 3.5E-235 T 29-03-2018 IPR004677 Cytochrome c oxidase cbb3-type, subunit I GO:0004129|GO:0045278|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 CDC59_RS08500 88affa543db0ca3d349e7339ccc0283e 485 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 16 446 2.5E-120 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS08500 88affa543db0ca3d349e7339ccc0283e 485 Gene3D G3DSA:1.20.210.10 5 473 3.9E-97 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS08500 88affa543db0ca3d349e7339ccc0283e 485 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 207 262 - T 29-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS17775 c189cbee48b3844bab7f21641b653327 625 Gene3D G3DSA:2.60.40.10 7 107 8.4E-21 T 29-03-2018 IPR013783 Immunoglobulin-like fold CDC59_RS17775 c189cbee48b3844bab7f21641b653327 625 Pfam PF11941 Domain of unknown function (DUF3459) 521 611 4.0E-14 T 29-03-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) CDC59_RS17775 c189cbee48b3844bab7f21641b653327 625 SMART SM00642 125 481 3.5E-8 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CDC59_RS17775 c189cbee48b3844bab7f21641b653327 625 TIGRFAM TIGR02402 trehalose_TreZ: malto-oligosyltrehalose trehalohydrolase 28 576 2.0E-212 T 29-03-2018 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00500+3.2.1.141|KEGG: 00520+3.2.1.14|MetaCyc: PWY-2661|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 CDC59_RS17775 c189cbee48b3844bab7f21641b653327 625 SUPERFAMILY SSF81296 11 107 9.4E-20 T 29-03-2018 IPR014756 Immunoglobulin E-set CDC59_RS17775 c189cbee48b3844bab7f21641b653327 625 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 17 90 4.8E-7 T 29-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 CDC59_RS17775 c189cbee48b3844bab7f21641b653327 625 Gene3D G3DSA:1.10.10.760 456 498 1.0E-16 T 29-03-2018 CDC59_RS17775 c189cbee48b3844bab7f21641b653327 625 SUPERFAMILY SSF51445 104 529 5.56E-99 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CDC59_RS17775 c189cbee48b3844bab7f21641b653327 625 Gene3D G3DSA:3.20.20.80 118 450 1.7E-58 T 29-03-2018 CDC59_RS17775 c189cbee48b3844bab7f21641b653327 625 Pfam PF00128 Alpha amylase, catalytic domain 139 225 2.6E-9 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CDC59_RS17775 c189cbee48b3844bab7f21641b653327 625 PIRSF PIRSF006337 14 614 8.6E-225 T 29-03-2018 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00500+3.2.1.141|KEGG: 00520+3.2.1.14|MetaCyc: PWY-2661|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 CDC59_RS17775 c189cbee48b3844bab7f21641b653327 625 Gene3D G3DSA:2.60.40.1180 542 615 1.3E-13 T 29-03-2018 CDC59_RS09845 4e8ee5b6c9425d9b2b1a381d3d580d19 437 Gene3D G3DSA:3.90.1580.10 171 437 1.2E-55 T 29-03-2018 CDC59_RS09845 4e8ee5b6c9425d9b2b1a381d3d580d19 437 TIGRFAM TIGR03440 egtB_TIGR03440: ergothioneine biosynthesis protein EgtB 20 434 1.1E-170 T 29-03-2018 IPR017806 Ergothioneine biosynthesis protein EgtB GO:0052699 CDC59_RS09845 4e8ee5b6c9425d9b2b1a381d3d580d19 437 SUPERFAMILY SSF56436 185 435 1.04E-70 T 29-03-2018 IPR016187 C-type lectin fold CDC59_RS09845 4e8ee5b6c9425d9b2b1a381d3d580d19 437 Gene3D G3DSA:1.20.120.450 8 164 6.8E-10 T 29-03-2018 CDC59_RS09845 4e8ee5b6c9425d9b2b1a381d3d580d19 437 Pfam PF03781 Sulfatase-modifying factor enzyme 1 358 434 6.9E-9 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 CDC59_RS09845 4e8ee5b6c9425d9b2b1a381d3d580d19 437 Pfam PF03781 Sulfatase-modifying factor enzyme 1 186 331 1.2E-24 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 CDC59_RS09845 4e8ee5b6c9425d9b2b1a381d3d580d19 437 Pfam PF12867 DinB superfamily 20 152 2.8E-15 T 29-03-2018 IPR024775 DinB-like domain CDC59_RS09845 4e8ee5b6c9425d9b2b1a381d3d580d19 437 SUPERFAMILY SSF109854 10 149 1.92E-5 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CDC59_RS00985 9d40408d9fdb24aaef9904ff77189513 127 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 49 78 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CDC59_RS00985 9d40408d9fdb24aaef9904ff77189513 127 SUPERFAMILY SSF51230 4 124 1.01E-39 T 29-03-2018 IPR011053 Single hybrid motif CDC59_RS00985 9d40408d9fdb24aaef9904ff77189513 127 Pfam PF01597 Glycine cleavage H-protein 8 123 2.9E-44 T 29-03-2018 IPR033753 Glycine cleavage system H-protein/Simiate CDC59_RS00985 9d40408d9fdb24aaef9904ff77189513 127 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 123 6.6E-46 T 29-03-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 CDC59_RS00985 9d40408d9fdb24aaef9904ff77189513 127 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 5 126 39.78 T 29-03-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 CDC59_RS00985 9d40408d9fdb24aaef9904ff77189513 127 Gene3D G3DSA:2.40.50.100 6 126 2.3E-41 T 29-03-2018 CDC59_RS07300 3b8dcf463fd23174a3f3243677ffa133 326 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 3 326 71.239 T 29-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CDC59_RS07300 3b8dcf463fd23174a3f3243677ffa133 326 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 4 326 1.1E-127 T 29-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CDC59_RS07300 3b8dcf463fd23174a3f3243677ffa133 326 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 114 191 4.5E-34 T 29-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CDC59_RS07300 3b8dcf463fd23174a3f3243677ffa133 326 Gene3D G3DSA:3.40.47.10 169 326 1.4E-43 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS07300 3b8dcf463fd23174a3f3243677ffa133 326 Gene3D G3DSA:3.40.47.10 4 168 4.4E-41 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS07300 3b8dcf463fd23174a3f3243677ffa133 326 SUPERFAMILY SSF53901 4 326 5.77E-74 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS07300 3b8dcf463fd23174a3f3243677ffa133 326 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 240 325 1.2E-36 T 29-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CDC59_RS07715 1916541ce575c478b6c92d1012fd4e02 276 SUPERFAMILY SSF47240 73 249 1.37E-18 T 29-03-2018 IPR009078 Ferritin-like superfamily CDC59_RS07715 1916541ce575c478b6c92d1012fd4e02 276 PIRSF PIRSF012318 5 276 6.0E-106 T 29-03-2018 IPR011197 Uncharacterised conserved protein UCP012318 CDC59_RS07715 1916541ce575c478b6c92d1012fd4e02 276 Pfam PF04305 Protein of unknown function (DUF455) 22 269 4.6E-96 T 29-03-2018 IPR007402 Protein of unknown function DUF455 CDC59_RS07715 1916541ce575c478b6c92d1012fd4e02 276 Gene3D G3DSA:1.20.1260.10 73 247 1.7E-40 T 29-03-2018 IPR012347 Ferritin-related CDC59_RS18705 adcc7f1dbb12579d5dfd704d1fe08484 310 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 108 279 2.9E-48 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CDC59_RS18705 adcc7f1dbb12579d5dfd704d1fe08484 310 SUPERFAMILY SSF52283 1 135 6.38E-26 T 29-03-2018 CDC59_RS18705 adcc7f1dbb12579d5dfd704d1fe08484 310 SUPERFAMILY SSF51735 100 280 3.43E-52 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS18705 adcc7f1dbb12579d5dfd704d1fe08484 310 Gene3D G3DSA:3.40.50.720 113 282 1.7E-50 T 29-03-2018 CDC59_RS18705 adcc7f1dbb12579d5dfd704d1fe08484 310 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 12 310 1.5E-16 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CDC59_RS18705 adcc7f1dbb12579d5dfd704d1fe08484 310 Gene3D G3DSA:3.40.50.720 2 112 2.8E-26 T 29-03-2018 CDC59_RS22165 f2829e633e6a5679ef2aab6fc70d4b72 298 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 8 289 8.0E-70 T 29-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CDC59_RS22165 f2829e633e6a5679ef2aab6fc70d4b72 298 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 4 290 43.03 T 29-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CDC59_RS22165 f2829e633e6a5679ef2aab6fc70d4b72 298 Gene3D G3DSA:3.20.20.70 1 296 1.4E-95 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS22165 f2829e633e6a5679ef2aab6fc70d4b72 298 Pfam PF00701 Dihydrodipicolinate synthetase family 5 288 2.5E-78 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CDC59_RS22165 f2829e633e6a5679ef2aab6fc70d4b72 298 SMART SM01130 4 292 1.6E-110 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CDC59_RS22165 f2829e633e6a5679ef2aab6fc70d4b72 298 PRINTS PR00146 Dihydrodipicolinate synthase signature 38 59 1.4E-21 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CDC59_RS22165 f2829e633e6a5679ef2aab6fc70d4b72 298 PRINTS PR00146 Dihydrodipicolinate synthase signature 106 122 1.4E-21 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CDC59_RS22165 f2829e633e6a5679ef2aab6fc70d4b72 298 PRINTS PR00146 Dihydrodipicolinate synthase signature 74 92 1.4E-21 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CDC59_RS22165 f2829e633e6a5679ef2aab6fc70d4b72 298 PRINTS PR00146 Dihydrodipicolinate synthase signature 131 148 1.4E-21 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CDC59_RS22165 f2829e633e6a5679ef2aab6fc70d4b72 298 PIRSF PIRSF001365 1 295 8.5E-88 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CDC59_RS22165 f2829e633e6a5679ef2aab6fc70d4b72 298 SUPERFAMILY SSF51569 3 289 7.64E-93 T 29-03-2018 CDC59_RS16105 6d760a0ae9e4dacbfdb85f748d08b46a 508 Gene3D G3DSA:1.20.1600.10 31 497 3.8E-90 T 29-03-2018 CDC59_RS16105 6d760a0ae9e4dacbfdb85f748d08b46a 508 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 23 492 3.3E-121 T 29-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 CDC59_RS16105 6d760a0ae9e4dacbfdb85f748d08b46a 508 Pfam PF02321 Outer membrane efflux protein 310 490 1.4E-21 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CDC59_RS16105 6d760a0ae9e4dacbfdb85f748d08b46a 508 Pfam PF02321 Outer membrane efflux protein 90 281 5.5E-18 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CDC59_RS16105 6d760a0ae9e4dacbfdb85f748d08b46a 508 SUPERFAMILY SSF56954 12 43 1.57E-94 T 29-03-2018 CDC59_RS16105 6d760a0ae9e4dacbfdb85f748d08b46a 508 SUPERFAMILY SSF56954 80 495 1.57E-94 T 29-03-2018 CDC59_RS20535 063586ec355b049c87b2684d4685670d 392 SUPERFAMILY SSF53067 159 391 2.16E-76 T 29-03-2018 CDC59_RS20535 063586ec355b049c87b2684d4685670d 392 Pfam PF00871 Acetokinase family 4 384 4.2E-109 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CDC59_RS20535 063586ec355b049c87b2684d4685670d 392 PRINTS PR00471 Acetate kinase family signature 4 15 1.5E-38 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CDC59_RS20535 063586ec355b049c87b2684d4685670d 392 PRINTS PR00471 Acetate kinase family signature 297 310 1.5E-38 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CDC59_RS20535 063586ec355b049c87b2684d4685670d 392 PRINTS PR00471 Acetate kinase family signature 174 187 1.5E-38 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CDC59_RS20535 063586ec355b049c87b2684d4685670d 392 PRINTS PR00471 Acetate kinase family signature 371 383 1.5E-38 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CDC59_RS20535 063586ec355b049c87b2684d4685670d 392 PRINTS PR00471 Acetate kinase family signature 203 224 1.5E-38 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CDC59_RS20535 063586ec355b049c87b2684d4685670d 392 PRINTS PR00471 Acetate kinase family signature 319 335 1.5E-38 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CDC59_RS20535 063586ec355b049c87b2684d4685670d 392 PIRSF PIRSF000722 1 392 1.0E-139 T 29-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CDC59_RS20535 063586ec355b049c87b2684d4685670d 392 SUPERFAMILY SSF53067 1 194 1.75E-60 T 29-03-2018 CDC59_RS20535 063586ec355b049c87b2684d4685670d 392 Hamap MF_00020 Acetate kinase [ackA]. 1 392 158.336 T 29-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CDC59_RS20535 063586ec355b049c87b2684d4685670d 392 Gene3D G3DSA:3.30.420.40 196 392 1.8E-69 T 29-03-2018 CDC59_RS20535 063586ec355b049c87b2684d4685670d 392 TIGRFAM TIGR00016 ackA: acetate kinase 2 387 1.3E-108 T 29-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CDC59_RS20535 063586ec355b049c87b2684d4685670d 392 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 4 15 - T 29-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CDC59_RS20535 063586ec355b049c87b2684d4685670d 392 Gene3D G3DSA:3.30.420.40 3 194 2.9E-62 T 29-03-2018 CDC59_RS12245 172aa3ea440834caeffcb2ebcf87126c 719 Gene3D G3DSA:3.30.70.20 241 344 3.8E-9 T 29-03-2018 CDC59_RS12245 172aa3ea440834caeffcb2ebcf87126c 719 Gene3D G3DSA:3.30.70.20 572 596 3.5E-5 T 29-03-2018 CDC59_RS12245 172aa3ea440834caeffcb2ebcf87126c 719 Gene3D G3DSA:3.30.70.20 597 627 1.7E-12 T 29-03-2018 CDC59_RS12245 172aa3ea440834caeffcb2ebcf87126c 719 Pfam PF12838 4Fe-4S dicluster domain 334 380 3.4E-8 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CDC59_RS12245 172aa3ea440834caeffcb2ebcf87126c 719 Pfam PF12838 4Fe-4S dicluster domain 590 636 2.5E-7 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CDC59_RS12245 172aa3ea440834caeffcb2ebcf87126c 719 Gene3D G3DSA:3.30.70.20 180 216 1.3E-5 T 29-03-2018 CDC59_RS12245 172aa3ea440834caeffcb2ebcf87126c 719 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 211 222 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CDC59_RS12245 172aa3ea440834caeffcb2ebcf87126c 719 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 591 602 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CDC59_RS12245 172aa3ea440834caeffcb2ebcf87126c 719 Gene3D G3DSA:3.30.70.20 372 413 3.4E-5 T 29-03-2018 CDC59_RS12245 172aa3ea440834caeffcb2ebcf87126c 719 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 366 377 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CDC59_RS12245 172aa3ea440834caeffcb2ebcf87126c 719 Gene3D G3DSA:3.30.70.20 345 371 7.8E-10 T 29-03-2018 CDC59_RS12245 172aa3ea440834caeffcb2ebcf87126c 719 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 622 633 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CDC59_RS12245 172aa3ea440834caeffcb2ebcf87126c 719 SUPERFAMILY SSF54862 206 387 4.82E-59 T 29-03-2018 CDC59_RS12245 172aa3ea440834caeffcb2ebcf87126c 719 SUPERFAMILY SSF54862 582 705 4.82E-59 T 29-03-2018 CDC59_RS12245 172aa3ea440834caeffcb2ebcf87126c 719 Gene3D G3DSA:3.30.70.20 217 240 9.3E-9 T 29-03-2018 CDC59_RS12245 172aa3ea440834caeffcb2ebcf87126c 719 Gene3D G3DSA:3.30.70.20 628 674 2.0E-5 T 29-03-2018 CDC59_RS12245 172aa3ea440834caeffcb2ebcf87126c 719 Pfam PF00037 4Fe-4S binding domain 206 227 1.0E-6 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CDC59_RS02565 51d5299070ce1613b10559df04323eca 421 Gene3D G3DSA:3.65.10.10 224 421 4.4E-47 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CDC59_RS02565 51d5299070ce1613b10559df04323eca 421 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 418 5.8E-176 T 29-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDC59_RS02565 51d5299070ce1613b10559df04323eca 421 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 409 2.9E-111 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CDC59_RS02565 51d5299070ce1613b10559df04323eca 421 Gene3D G3DSA:3.65.10.10 21 223 2.8E-52 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CDC59_RS02565 51d5299070ce1613b10559df04323eca 421 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 419 45.206 T 29-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDC59_RS02565 51d5299070ce1613b10559df04323eca 421 SUPERFAMILY SSF55205 1 420 7.36E-145 T 29-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CDC59_RS07370 3e05fd127f57ae797b07a3714fb5853f 256 SUPERFAMILY SSF54768 106 220 2.2E-25 T 29-03-2018 CDC59_RS07370 3e05fd127f57ae797b07a3714fb5853f 256 Gene3D G3DSA:1.10.1520.10 1 147 1.7E-43 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CDC59_RS07370 3e05fd127f57ae797b07a3714fb5853f 256 ProSitePatterns PS00517 Ribonuclease III family signature. 35 43 - T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CDC59_RS07370 3e05fd127f57ae797b07a3714fb5853f 256 SUPERFAMILY SSF69065 2 154 3.66E-47 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CDC59_RS07370 3e05fd127f57ae797b07a3714fb5853f 256 Hamap MF_00104 Ribonuclease 3 [rnc]. 6 217 28.878 T 29-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 CDC59_RS07370 3e05fd127f57ae797b07a3714fb5853f 256 Gene3D G3DSA:3.30.160.20 148 249 1.7E-18 T 29-03-2018 CDC59_RS07370 3e05fd127f57ae797b07a3714fb5853f 256 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 6 219 6.5E-72 T 29-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 CDC59_RS07370 3e05fd127f57ae797b07a3714fb5853f 256 SMART SM00535 18 146 1.9E-51 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CDC59_RS07370 3e05fd127f57ae797b07a3714fb5853f 256 Pfam PF14622 Ribonuclease-III-like 17 138 2.3E-35 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CDC59_RS07370 3e05fd127f57ae797b07a3714fb5853f 256 Pfam PF00035 Double-stranded RNA binding motif 153 218 5.9E-12 T 29-03-2018 IPR014720 Double-stranded RNA-binding domain CDC59_RS07370 3e05fd127f57ae797b07a3714fb5853f 256 SMART SM00358 153 221 1.1E-13 T 29-03-2018 IPR014720 Double-stranded RNA-binding domain CDC59_RS06315 8578e43ae4840bdeed13fcbc3b48964f 324 Gene3D G3DSA:3.90.180.10 254 324 5.8E-6 T 29-03-2018 CDC59_RS06315 8578e43ae4840bdeed13fcbc3b48964f 324 SMART SM00829 11 322 2.9E-42 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CDC59_RS06315 8578e43ae4840bdeed13fcbc3b48964f 324 SUPERFAMILY SSF50129 2 144 2.2E-39 T 29-03-2018 IPR011032 GroES-like CDC59_RS06315 8578e43ae4840bdeed13fcbc3b48964f 324 SUPERFAMILY SSF51735 112 271 3.95E-50 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS06315 8578e43ae4840bdeed13fcbc3b48964f 324 Gene3D G3DSA:3.40.50.720 143 253 8.2E-27 T 29-03-2018 CDC59_RS06315 8578e43ae4840bdeed13fcbc3b48964f 324 Pfam PF00107 Zinc-binding dehydrogenase 151 256 2.4E-29 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CDC59_RS06315 8578e43ae4840bdeed13fcbc3b48964f 324 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 86 2.8E-8 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CDC59_RS06315 8578e43ae4840bdeed13fcbc3b48964f 324 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 140 161 - T 29-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 CDC59_RS06315 8578e43ae4840bdeed13fcbc3b48964f 324 Gene3D G3DSA:3.90.180.10 1 142 1.1E-43 T 29-03-2018 CDC59_RS14230 d4b45d89c5b3001079e9c1b525802bfd 262 TIGRFAM TIGR04406 LPS_export_lptB: LPS export ABC transporter ATP-binding protein 20 262 3.4E-117 T 29-03-2018 IPR030921 LPS export ABC transporter, ATP-binding protein LptB GO:0043190|GO:0055085 CDC59_RS14230 d4b45d89c5b3001079e9c1b525802bfd 262 Gene3D G3DSA:3.40.50.300 3 260 2.7E-61 T 29-03-2018 CDC59_RS14230 d4b45d89c5b3001079e9c1b525802bfd 262 SUPERFAMILY SSF52540 21 258 2.44E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS14230 d4b45d89c5b3001079e9c1b525802bfd 262 Pfam PF00005 ABC transporter 36 187 2.4E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS14230 d4b45d89c5b3001079e9c1b525802bfd 262 SMART SM00382 45 252 9.0E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS14230 d4b45d89c5b3001079e9c1b525802bfd 262 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 236 257 5.9E-6 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CDC59_RS14230 d4b45d89c5b3001079e9c1b525802bfd 262 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS00270 27eab3db0c81761e928e56e7a60c68f5 293 SUPERFAMILY SSF109709 104 186 2.88E-13 T 29-03-2018 CDC59_RS00270 27eab3db0c81761e928e56e7a60c68f5 293 SUPERFAMILY SSF110849 14 127 7.46E-12 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CDC59_RS00270 27eab3db0c81761e928e56e7a60c68f5 293 Gene3D G3DSA:3.90.1530.10 11 104 2.2E-10 T 29-03-2018 CDC59_RS00270 27eab3db0c81761e928e56e7a60c68f5 293 Pfam PF07506 RepB plasmid partitioning protein 101 282 1.2E-42 T 29-03-2018 IPR011111 RepB plasmid partition CDC59_RS00270 27eab3db0c81761e928e56e7a60c68f5 293 Pfam PF02195 ParB-like nuclease domain 15 93 8.9E-5 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CDC59_RS01030 86cc6344bb7278f1bda8ae488e505e40 236 SUPERFAMILY SSF46894 157 236 3.74E-19 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CDC59_RS01030 86cc6344bb7278f1bda8ae488e505e40 236 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 206 218 6.0E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS01030 86cc6344bb7278f1bda8ae488e505e40 236 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 190 6.0E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS01030 86cc6344bb7278f1bda8ae488e505e40 236 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 190 206 6.0E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS01030 86cc6344bb7278f1bda8ae488e505e40 236 Pfam PF03472 Autoinducer binding domain 18 157 3.0E-32 T 29-03-2018 IPR005143 Transcription factor LuxR-like, autoinducer-binding domain CDC59_RS01030 86cc6344bb7278f1bda8ae488e505e40 236 ProSitePatterns PS00622 LuxR-type HTH domain signature. 190 217 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS01030 86cc6344bb7278f1bda8ae488e505e40 236 Gene3D G3DSA:3.30.450.80 1 164 1.3E-36 T 29-03-2018 CDC59_RS01030 86cc6344bb7278f1bda8ae488e505e40 236 SUPERFAMILY SSF75516 4 164 3.01E-39 T 29-03-2018 IPR005143 Transcription factor LuxR-like, autoinducer-binding domain CDC59_RS01030 86cc6344bb7278f1bda8ae488e505e40 236 SMART SM00421 173 230 3.9E-20 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS01030 86cc6344bb7278f1bda8ae488e505e40 236 Pfam PF00196 Bacterial regulatory proteins, luxR family 175 230 4.2E-18 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS01030 86cc6344bb7278f1bda8ae488e505e40 236 Gene3D G3DSA:1.10.10.10 175 236 1.7E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS13350 431728de2968e4fa0a11419dadc65147 419 SUPERFAMILY SSF53748 27 410 7.66E-141 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDC59_RS13350 431728de2968e4fa0a11419dadc65147 419 PIRSF PIRSF000724 19 417 7.1E-138 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDC59_RS13350 431728de2968e4fa0a11419dadc65147 419 Pfam PF00162 Phosphoglycerate kinase 29 400 9.3E-140 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDC59_RS13350 431728de2968e4fa0a11419dadc65147 419 PRINTS PR00477 Phosphoglycerate kinase family signature 154 176 6.3E-79 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDC59_RS13350 431728de2968e4fa0a11419dadc65147 419 PRINTS PR00477 Phosphoglycerate kinase family signature 53 75 6.3E-79 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDC59_RS13350 431728de2968e4fa0a11419dadc65147 419 PRINTS PR00477 Phosphoglycerate kinase family signature 208 227 6.3E-79 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDC59_RS13350 431728de2968e4fa0a11419dadc65147 419 PRINTS PR00477 Phosphoglycerate kinase family signature 126 141 6.3E-79 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDC59_RS13350 431728de2968e4fa0a11419dadc65147 419 PRINTS PR00477 Phosphoglycerate kinase family signature 330 355 6.3E-79 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDC59_RS13350 431728de2968e4fa0a11419dadc65147 419 PRINTS PR00477 Phosphoglycerate kinase family signature 386 403 6.3E-79 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDC59_RS13350 431728de2968e4fa0a11419dadc65147 419 PRINTS PR00477 Phosphoglycerate kinase family signature 31 47 6.3E-79 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDC59_RS13350 431728de2968e4fa0a11419dadc65147 419 PRINTS PR00477 Phosphoglycerate kinase family signature 363 374 6.3E-79 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDC59_RS13350 431728de2968e4fa0a11419dadc65147 419 PRINTS PR00477 Phosphoglycerate kinase family signature 185 207 6.3E-79 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDC59_RS13350 431728de2968e4fa0a11419dadc65147 419 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 36 46 - T 29-03-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDC59_RS13350 431728de2968e4fa0a11419dadc65147 419 Gene3D G3DSA:3.40.50.1260 24 196 6.1E-60 T 29-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDC59_RS13350 431728de2968e4fa0a11419dadc65147 419 Gene3D G3DSA:3.40.50.1260 197 398 2.0E-75 T 29-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDC59_RS13350 431728de2968e4fa0a11419dadc65147 419 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 23 410 39.064 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDC59_RS07645 1b0d8000bfd72280f41d6f61a7367330 845 Pfam PF12706 Beta-lactamase superfamily domain 583 743 1.6E-8 T 29-03-2018 IPR001279 Metallo-beta-lactamase CDC59_RS07645 1b0d8000bfd72280f41d6f61a7367330 845 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 265 466 7.8E-24 T 29-03-2018 IPR004477 ComEC/Rec2-related protein CDC59_RS07645 1b0d8000bfd72280f41d6f61a7367330 845 Gene3D G3DSA:3.60.15.10 564 808 1.9E-25 T 29-03-2018 IPR001279 Metallo-beta-lactamase CDC59_RS07645 1b0d8000bfd72280f41d6f61a7367330 845 TIGRFAM TIGR00361 ComEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 155 801 1.2E-96 T 29-03-2018 IPR004797 Competence protein ComEC/Rec2 GO:0016021|GO:0030420 CDC59_RS07645 1b0d8000bfd72280f41d6f61a7367330 845 SUPERFAMILY SSF56281 559 824 5.11E-44 T 29-03-2018 IPR001279 Metallo-beta-lactamase CDC59_RS07645 1b0d8000bfd72280f41d6f61a7367330 845 Pfam PF03772 Competence protein 244 529 2.0E-59 T 29-03-2018 IPR004477 ComEC/Rec2-related protein CDC59_RS07645 1b0d8000bfd72280f41d6f61a7367330 845 Pfam PF13567 Domain of unknown function (DUF4131) 23 196 3.3E-24 T 29-03-2018 IPR025405 Domain of unknown function DUF4131 CDC59_RS07645 1b0d8000bfd72280f41d6f61a7367330 845 SMART SM00849 572 772 0.0036 T 29-03-2018 IPR001279 Metallo-beta-lactamase CDC59_RS22735 a6c32a23b4157cc166361349fc9ff934 490 Gene3D G3DSA:2.40.10.10 193 294 2.7E-36 T 29-03-2018 CDC59_RS22735 a6c32a23b4157cc166361349fc9ff934 490 SUPERFAMILY SSF50156 403 487 1.17E-17 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CDC59_RS22735 a6c32a23b4157cc166361349fc9ff934 490 Gene3D G3DSA:2.40.10.10 55 192 8.2E-36 T 29-03-2018 CDC59_RS22735 a6c32a23b4157cc166361349fc9ff934 490 Pfam PF13180 PDZ domain 405 483 5.9E-11 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CDC59_RS22735 a6c32a23b4157cc166361349fc9ff934 490 Pfam PF13180 PDZ domain 294 385 1.8E-17 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CDC59_RS22735 a6c32a23b4157cc166361349fc9ff934 490 SUPERFAMILY SSF50156 252 376 2.1E-23 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CDC59_RS22735 a6c32a23b4157cc166361349fc9ff934 490 Pfam PF13365 Trypsin-like peptidase domain 122 255 4.7E-36 T 29-03-2018 CDC59_RS22735 a6c32a23b4157cc166361349fc9ff934 490 SUPERFAMILY SSF50494 57 285 1.1E-63 T 29-03-2018 IPR009003 Peptidase S1, PA clan CDC59_RS22735 a6c32a23b4157cc166361349fc9ff934 490 SMART SM00228 404 480 6.6E-11 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CDC59_RS22735 a6c32a23b4157cc166361349fc9ff934 490 SMART SM00228 294 376 2.0E-13 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CDC59_RS22735 a6c32a23b4157cc166361349fc9ff934 490 Gene3D G3DSA:2.30.42.10 406 490 4.8E-18 T 29-03-2018 CDC59_RS22735 a6c32a23b4157cc166361349fc9ff934 490 PRINTS PR00834 HtrA/DegQ protease family signature 248 265 1.2E-47 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CDC59_RS22735 a6c32a23b4157cc166361349fc9ff934 490 PRINTS PR00834 HtrA/DegQ protease family signature 152 172 1.2E-47 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CDC59_RS22735 a6c32a23b4157cc166361349fc9ff934 490 PRINTS PR00834 HtrA/DegQ protease family signature 192 216 1.2E-47 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CDC59_RS22735 a6c32a23b4157cc166361349fc9ff934 490 PRINTS PR00834 HtrA/DegQ protease family signature 334 346 1.2E-47 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CDC59_RS22735 a6c32a23b4157cc166361349fc9ff934 490 PRINTS PR00834 HtrA/DegQ protease family signature 226 243 1.2E-47 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CDC59_RS22735 a6c32a23b4157cc166361349fc9ff934 490 PRINTS PR00834 HtrA/DegQ protease family signature 131 143 1.2E-47 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CDC59_RS22735 a6c32a23b4157cc166361349fc9ff934 490 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 59 485 2.3E-153 T 29-03-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 CDC59_RS22735 a6c32a23b4157cc166361349fc9ff934 490 Gene3D G3DSA:2.30.42.10 295 398 3.2E-25 T 29-03-2018 CDC59_RS08130 9419bbad4cf9ebc71b9ffdbb46eaf7e3 450 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 432 442 - T 29-03-2018 IPR030391 RNA methyltransferase TrmA, conserved site CDC59_RS08130 9419bbad4cf9ebc71b9ffdbb46eaf7e3 450 Gene3D G3DSA:3.40.50.150 77 448 4.4E-53 T 29-03-2018 CDC59_RS08130 9419bbad4cf9ebc71b9ffdbb46eaf7e3 450 Gene3D G3DSA:2.40.50.140 5 76 8.5E-20 T 29-03-2018 CDC59_RS08130 9419bbad4cf9ebc71b9ffdbb46eaf7e3 450 Hamap MF_01010 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD [rlmD]. 6 450 68.096 T 29-03-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 CDC59_RS08130 9419bbad4cf9ebc71b9ffdbb46eaf7e3 450 SUPERFAMILY SSF50249 7 67 1.31E-8 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDC59_RS08130 9419bbad4cf9ebc71b9ffdbb46eaf7e3 450 SUPERFAMILY SSF53335 70 449 3.64E-77 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS08130 9419bbad4cf9ebc71b9ffdbb46eaf7e3 450 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 268 446 1.3E-15 T 29-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 CDC59_RS21835 818c0135d2aa392b6e984c991c46b1f0 496 Pfam PF07969 Amidohydrolase family 51 465 2.6E-41 T 29-03-2018 IPR013108 Amidohydrolase 3 CDC59_RS21835 818c0135d2aa392b6e984c991c46b1f0 496 SUPERFAMILY SSF51338 420 480 9.12E-19 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CDC59_RS21835 818c0135d2aa392b6e984c991c46b1f0 496 SUPERFAMILY SSF51338 4 61 9.12E-19 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CDC59_RS21835 818c0135d2aa392b6e984c991c46b1f0 496 Gene3D G3DSA:3.20.20.140 70 401 6.0E-77 T 29-03-2018 CDC59_RS21835 818c0135d2aa392b6e984c991c46b1f0 496 SUPERFAMILY SSF51556 62 420 2.13E-89 T 29-03-2018 IPR032466 Metal-dependent hydrolase CDC59_RS21835 818c0135d2aa392b6e984c991c46b1f0 496 Gene3D G3DSA:2.30.40.10 402 468 2.5E-11 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CDC59_RS21835 818c0135d2aa392b6e984c991c46b1f0 496 Gene3D G3DSA:2.30.40.10 1 69 2.3E-16 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CDC59_RS14725 b828b93848ef6efb36f0a50f74b6a3b8 211 Pfam PF03886 ABC-type transport auxiliary lipoprotein component 50 187 1.6E-10 T 29-03-2018 IPR005586 ABC-type transport auxiliary lipoprotein component CDC59_RS14725 b828b93848ef6efb36f0a50f74b6a3b8 211 SUPERFAMILY SSF159594 33 196 2.88E-32 T 29-03-2018 CDC59_RS14725 b828b93848ef6efb36f0a50f74b6a3b8 211 Gene3D G3DSA:3.40.50.10610 19 207 9.3E-33 T 29-03-2018 IPR005586 ABC-type transport auxiliary lipoprotein component CDC59_RS08895 dbc336998b68015903136eacea45a041 271 SMART SM00448 5 121 3.2E-22 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS08895 dbc336998b68015903136eacea45a041 271 Pfam PF04397 LytTr DNA-binding domain 177 271 4.2E-22 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CDC59_RS08895 dbc336998b68015903136eacea45a041 271 Gene3D G3DSA:2.40.50.40 166 235 4.3E-15 T 29-03-2018 CDC59_RS08895 dbc336998b68015903136eacea45a041 271 Pfam PF00072 Response regulator receiver domain 8 121 1.9E-18 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS08895 dbc336998b68015903136eacea45a041 271 SMART SM00850 175 271 9.1E-24 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CDC59_RS08895 dbc336998b68015903136eacea45a041 271 SUPERFAMILY SSF52172 4 139 7.68E-27 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS08895 dbc336998b68015903136eacea45a041 271 Gene3D G3DSA:3.40.50.2300 1 146 2.4E-23 T 29-03-2018 CDC59_RS06605 a7ab29da055f12177d053edc41605efe 336 Gene3D G3DSA:3.40.190.10 184 269 4.8E-25 T 29-03-2018 CDC59_RS06605 a7ab29da055f12177d053edc41605efe 336 SUPERFAMILY SSF53850 93 303 2.17E-45 T 29-03-2018 CDC59_RS06605 a7ab29da055f12177d053edc41605efe 336 Gene3D G3DSA:3.40.190.10 94 183 5.1E-15 T 29-03-2018 CDC59_RS06605 a7ab29da055f12177d053edc41605efe 336 SUPERFAMILY SSF46785 10 91 3.63E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS06605 a7ab29da055f12177d053edc41605efe 336 Pfam PF03466 LysR substrate binding domain 93 299 2.9E-46 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS06605 a7ab29da055f12177d053edc41605efe 336 Gene3D G3DSA:1.10.10.10 3 89 4.9E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS06605 a7ab29da055f12177d053edc41605efe 336 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 68 4.5E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS06605 a7ab29da055f12177d053edc41605efe 336 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 2.5E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS06605 a7ab29da055f12177d053edc41605efe 336 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 2.5E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS06605 a7ab29da055f12177d053edc41605efe 336 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 2.5E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS18550 5d3d2ede3819bb5549a6438a9f4458dc 702 TIGRFAM TIGR03361 VI_Rhs_Vgr: type VI secretion system Vgr family protein 88 607 5.3E-155 T 29-03-2018 IPR017847 Type VI secretion system, RhsGE-associated Vgr family subset CDC59_RS18550 5d3d2ede3819bb5549a6438a9f4458dc 702 Pfam PF05954 Phage late control gene D protein (GPD) 108 425 8.8E-80 T 29-03-2018 CDC59_RS18550 5d3d2ede3819bb5549a6438a9f4458dc 702 TIGRFAM TIGR01646 vgr_GE: Rhs element Vgr protein 101 593 2.7E-116 T 29-03-2018 IPR006533 Type VI secretion system, RhsGE-associated Vgr protein CDC59_RS18550 5d3d2ede3819bb5549a6438a9f4458dc 702 SUPERFAMILY SSF69349 533 699 2.98E-23 T 29-03-2018 CDC59_RS18550 5d3d2ede3819bb5549a6438a9f4458dc 702 SUPERFAMILY SSF69255 456 543 5.75E-29 T 29-03-2018 CDC59_RS18550 5d3d2ede3819bb5549a6438a9f4458dc 702 SUPERFAMILY SSF69279 285 456 6.29E-31 T 29-03-2018 CDC59_RS18550 5d3d2ede3819bb5549a6438a9f4458dc 702 SUPERFAMILY SSF69279 89 277 8.5E-51 T 29-03-2018 CDC59_RS18550 5d3d2ede3819bb5549a6438a9f4458dc 702 Gene3D G3DSA:2.40.50.230 462 543 2.9E-31 T 29-03-2018 IPR006531 Gp5 N-terminal CDC59_RS18550 5d3d2ede3819bb5549a6438a9f4458dc 702 Gene3D G3DSA:3.55.50.10 191 282 4.2E-26 T 29-03-2018 CDC59_RS08110 21222f79aa4f2cc231d8cff034e96bd5 308 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 225 240 - T 29-03-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 CDC59_RS08110 21222f79aa4f2cc231d8cff034e96bd5 308 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 87 305 1.7E-52 T 29-03-2018 CDC59_RS08110 21222f79aa4f2cc231d8cff034e96bd5 308 SUPERFAMILY SSF53335 96 304 3.54E-36 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS08110 21222f79aa4f2cc231d8cff034e96bd5 308 Hamap MF_00090 Protein-L-isoaspartate O-methyltransferase [pcm]. 82 307 33.406 T 29-03-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 CDC59_RS08110 21222f79aa4f2cc231d8cff034e96bd5 308 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 83 306 3.7E-54 T 29-03-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 CDC59_RS08110 21222f79aa4f2cc231d8cff034e96bd5 308 Gene3D G3DSA:3.40.50.150 67 307 6.3E-33 T 29-03-2018 CDC59_RS17785 165e2bfd3b1eaad3fe1ed2a0ec63db92 771 SUPERFAMILY SSF51445 223 659 4.56E-114 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CDC59_RS17785 165e2bfd3b1eaad3fe1ed2a0ec63db92 771 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 671 771 9.5E-19 T 29-03-2018 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 CDC59_RS17785 165e2bfd3b1eaad3fe1ed2a0ec63db92 771 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 146 770 1.4E-269 T 29-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 CDC59_RS17785 165e2bfd3b1eaad3fe1ed2a0ec63db92 771 Pfam PF00128 Alpha amylase, catalytic domain 318 388 7.8E-5 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CDC59_RS17785 165e2bfd3b1eaad3fe1ed2a0ec63db92 771 Gene3D G3DSA:3.20.20.80 278 676 5.6E-74 T 29-03-2018 CDC59_RS17785 165e2bfd3b1eaad3fe1ed2a0ec63db92 771 Gene3D G3DSA:2.60.40.1180 677 771 4.7E-29 T 29-03-2018 CDC59_RS17785 165e2bfd3b1eaad3fe1ed2a0ec63db92 771 SMART SM00642 291 662 6.9E-7 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CDC59_RS17785 165e2bfd3b1eaad3fe1ed2a0ec63db92 771 Gene3D G3DSA:2.60.40.10 143 263 1.3E-30 T 29-03-2018 IPR013783 Immunoglobulin-like fold CDC59_RS17785 165e2bfd3b1eaad3fe1ed2a0ec63db92 771 Gene3D G3DSA:2.60.40.10 30 142 6.0E-7 T 29-03-2018 IPR013783 Immunoglobulin-like fold CDC59_RS17785 165e2bfd3b1eaad3fe1ed2a0ec63db92 771 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 162 247 1.0E-21 T 29-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 CDC59_RS17785 165e2bfd3b1eaad3fe1ed2a0ec63db92 771 PIRSF PIRSF000463 32 771 5.6E-284 T 29-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 CDC59_RS17785 165e2bfd3b1eaad3fe1ed2a0ec63db92 771 SUPERFAMILY SSF51011 666 770 4.56E-30 T 29-03-2018 CDC59_RS17785 165e2bfd3b1eaad3fe1ed2a0ec63db92 771 SUPERFAMILY SSF81296 175 247 7.7E-10 T 29-03-2018 IPR014756 Immunoglobulin E-set CDC59_RS17785 165e2bfd3b1eaad3fe1ed2a0ec63db92 771 SUPERFAMILY SSF81296 41 151 3.64E-12 T 29-03-2018 IPR014756 Immunoglobulin E-set CDC59_RS17785 165e2bfd3b1eaad3fe1ed2a0ec63db92 771 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 138 771 44.004 T 29-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 CDC59_RS00070 ab505d052411324e1ba82f72be31c958 399 Gene3D G3DSA:1.20.1600.10 6 330 1.6E-32 T 29-03-2018 CDC59_RS00070 ab505d052411324e1ba82f72be31c958 399 Pfam PF13533 Biotin-lipoyl like 66 114 1.3E-11 T 29-03-2018 CDC59_RS00070 ab505d052411324e1ba82f72be31c958 399 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 41 377 1.6E-83 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 CDC59_RS00070 ab505d052411324e1ba82f72be31c958 399 SUPERFAMILY SSF111369 53 302 2.88E-80 T 29-03-2018 CDC59_RS02445 974e98026d25ed04e06bf0ae9bb41986 113 SMART SM01219 4 111 1.2E-46 T 29-03-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 CDC59_RS02445 974e98026d25ed04e06bf0ae9bb41986 113 ProSitePatterns PS01344 Frataxin family signature. 55 69 - T 29-03-2018 IPR020895 Frataxin conserved site Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 CDC59_RS02445 974e98026d25ed04e06bf0ae9bb41986 113 TIGRFAM TIGR03421 FeS_CyaY: iron donor protein CyaY 5 109 5.1E-36 T 29-03-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 CDC59_RS02445 974e98026d25ed04e06bf0ae9bb41986 113 SUPERFAMILY SSF55387 4 110 1.24E-31 T 29-03-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 CDC59_RS02445 974e98026d25ed04e06bf0ae9bb41986 113 Hamap MF_00142 Protein CyaY [cyaY]. 4 110 25.676 T 29-03-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 CDC59_RS02445 974e98026d25ed04e06bf0ae9bb41986 113 Gene3D G3DSA:3.30.920.10 1 112 3.3E-27 T 29-03-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 CDC59_RS02445 974e98026d25ed04e06bf0ae9bb41986 113 Pfam PF01491 Frataxin-like domain 4 107 5.5E-24 T 29-03-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 CDC59_RS10210 89936e52f9f1e5ce3b351f0aa276529f 1039 Gene3D G3DSA:3.30.70.1430 45 149 2.5E-29 T 29-03-2018 CDC59_RS10210 89936e52f9f1e5ce3b351f0aa276529f 1039 SUPERFAMILY SSF82866 299 507 1.57E-33 T 29-03-2018 CDC59_RS10210 89936e52f9f1e5ce3b351f0aa276529f 1039 Pfam PF00873 AcrB/AcrD/AcrF family 10 1022 6.4E-171 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS10210 89936e52f9f1e5ce3b351f0aa276529f 1039 Gene3D G3DSA:3.30.70.1430 571 675 4.6E-12 T 29-03-2018 CDC59_RS10210 89936e52f9f1e5ce3b351f0aa276529f 1039 SUPERFAMILY SSF82714 723 806 1.02E-16 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS10210 89936e52f9f1e5ce3b351f0aa276529f 1039 PRINTS PR00702 Acriflavin resistance protein family signature 43 61 8.0E-14 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS10210 89936e52f9f1e5ce3b351f0aa276529f 1039 PRINTS PR00702 Acriflavin resistance protein family signature 401 425 8.0E-14 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS10210 89936e52f9f1e5ce3b351f0aa276529f 1039 PRINTS PR00702 Acriflavin resistance protein family signature 373 394 8.0E-14 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS10210 89936e52f9f1e5ce3b351f0aa276529f 1039 PRINTS PR00702 Acriflavin resistance protein family signature 479 502 8.0E-14 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS10210 89936e52f9f1e5ce3b351f0aa276529f 1039 SUPERFAMILY SSF82693 573 678 1.26E-7 T 29-03-2018 CDC59_RS10210 89936e52f9f1e5ce3b351f0aa276529f 1039 SUPERFAMILY SSF82693 275 330 1.96E-21 T 29-03-2018 CDC59_RS10210 89936e52f9f1e5ce3b351f0aa276529f 1039 SUPERFAMILY SSF82693 141 187 1.96E-21 T 29-03-2018 CDC59_RS10210 89936e52f9f1e5ce3b351f0aa276529f 1039 SUPERFAMILY SSF82866 806 1029 1.31E-45 T 29-03-2018 CDC59_RS10210 89936e52f9f1e5ce3b351f0aa276529f 1039 Gene3D G3DSA:3.30.70.1320 232 315 7.9E-16 T 29-03-2018 CDC59_RS10210 89936e52f9f1e5ce3b351f0aa276529f 1039 Gene3D G3DSA:3.30.2090.10 723 807 8.8E-18 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS10210 89936e52f9f1e5ce3b351f0aa276529f 1039 Gene3D G3DSA:1.20.1640.10 316 518 6.3E-32 T 29-03-2018 CDC59_RS10210 89936e52f9f1e5ce3b351f0aa276529f 1039 SUPERFAMILY SSF82714 190 271 6.54E-12 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS10210 89936e52f9f1e5ce3b351f0aa276529f 1039 SUPERFAMILY SSF82693 45 140 7.5E-18 T 29-03-2018 CDC59_RS10210 89936e52f9f1e5ce3b351f0aa276529f 1039 Gene3D G3DSA:1.20.1640.10 817 1027 3.1E-31 T 29-03-2018 CDC59_RS00580 5d80dddb7a352963b7243b264c1980de 285 Pfam PF04378 Ribosomal RNA large subunit methyltransferase D, RlmJ 33 275 8.7E-73 T 29-03-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 CDC59_RS00580 5d80dddb7a352963b7243b264c1980de 285 SUPERFAMILY SSF53335 9 281 1.16E-94 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS00580 5d80dddb7a352963b7243b264c1980de 285 Gene3D G3DSA:3.40.50.150 1 285 3.5E-87 T 29-03-2018 CDC59_RS00580 5d80dddb7a352963b7243b264c1980de 285 Hamap MF_00934 Ribosomal RNA large subunit methyltransferase J [rlmJ]. 2 272 39.852 T 29-03-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 CDC59_RS08760 305648e7c0c4eda163d0e521a7b1ef55 413 Gene3D G3DSA:3.40.640.10 53 280 1.3E-51 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDC59_RS08760 305648e7c0c4eda163d0e521a7b1ef55 413 Gene3D G3DSA:3.90.1150.10 281 405 1.1E-29 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS08760 305648e7c0c4eda163d0e521a7b1ef55 413 SUPERFAMILY SSF53383 5 402 4.49E-99 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS08760 305648e7c0c4eda163d0e521a7b1ef55 413 Pfam PF00155 Aminotransferase class I and II 36 395 4.4E-50 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CDC59_RS19470 af4fd0465aecd262e7c0747a0259c36a 247 SUPERFAMILY SSF52540 4 241 7.43E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS19470 af4fd0465aecd262e7c0747a0259c36a 247 Pfam PF00005 ABC transporter 20 170 6.6E-24 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS19470 af4fd0465aecd262e7c0747a0259c36a 247 Gene3D G3DSA:3.40.50.300 1 245 1.4E-48 T 29-03-2018 CDC59_RS19470 af4fd0465aecd262e7c0747a0259c36a 247 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS19470 af4fd0465aecd262e7c0747a0259c36a 247 SMART SM00382 29 215 2.0E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS10860 631f9fa798804830086d3bcd791a7f46 268 Gene3D G3DSA:3.90.350.10 80 212 0.0019 T 29-03-2018 IPR014736 Transposase, Tn5-like, core CDC59_RS10860 631f9fa798804830086d3bcd791a7f46 268 Pfam PF01609 Transposase DDE domain 100 254 2.4E-21 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS10860 631f9fa798804830086d3bcd791a7f46 268 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 11 83 1.1E-20 T 29-03-2018 IPR025161 Putative transposase IS4/IS5 family CDC59_RS18000 631f9fa798804830086d3bcd791a7f46 268 Gene3D G3DSA:3.90.350.10 80 212 0.0019 T 29-03-2018 IPR014736 Transposase, Tn5-like, core CDC59_RS18000 631f9fa798804830086d3bcd791a7f46 268 Pfam PF01609 Transposase DDE domain 100 254 2.4E-21 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS18000 631f9fa798804830086d3bcd791a7f46 268 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 11 83 1.1E-20 T 29-03-2018 IPR025161 Putative transposase IS4/IS5 family CDC59_RS21380 631f9fa798804830086d3bcd791a7f46 268 Gene3D G3DSA:3.90.350.10 80 212 0.0019 T 29-03-2018 IPR014736 Transposase, Tn5-like, core CDC59_RS21380 631f9fa798804830086d3bcd791a7f46 268 Pfam PF01609 Transposase DDE domain 100 254 2.4E-21 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS21380 631f9fa798804830086d3bcd791a7f46 268 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 11 83 1.1E-20 T 29-03-2018 IPR025161 Putative transposase IS4/IS5 family CDC59_RS00345 631f9fa798804830086d3bcd791a7f46 268 Gene3D G3DSA:3.90.350.10 80 212 0.0019 T 29-03-2018 IPR014736 Transposase, Tn5-like, core CDC59_RS00345 631f9fa798804830086d3bcd791a7f46 268 Pfam PF01609 Transposase DDE domain 100 254 2.4E-21 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS00345 631f9fa798804830086d3bcd791a7f46 268 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 11 83 1.1E-20 T 29-03-2018 IPR025161 Putative transposase IS4/IS5 family CDC59_RS23060 631f9fa798804830086d3bcd791a7f46 268 Gene3D G3DSA:3.90.350.10 80 212 0.0019 T 29-03-2018 IPR014736 Transposase, Tn5-like, core CDC59_RS23060 631f9fa798804830086d3bcd791a7f46 268 Pfam PF01609 Transposase DDE domain 100 254 2.4E-21 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS23060 631f9fa798804830086d3bcd791a7f46 268 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 11 83 1.1E-20 T 29-03-2018 IPR025161 Putative transposase IS4/IS5 family CDC59_RS15245 631f9fa798804830086d3bcd791a7f46 268 Gene3D G3DSA:3.90.350.10 80 212 0.0019 T 29-03-2018 IPR014736 Transposase, Tn5-like, core CDC59_RS15245 631f9fa798804830086d3bcd791a7f46 268 Pfam PF01609 Transposase DDE domain 100 254 2.4E-21 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS15245 631f9fa798804830086d3bcd791a7f46 268 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 11 83 1.1E-20 T 29-03-2018 IPR025161 Putative transposase IS4/IS5 family CDC59_RS03825 631f9fa798804830086d3bcd791a7f46 268 Gene3D G3DSA:3.90.350.10 80 212 0.0019 T 29-03-2018 IPR014736 Transposase, Tn5-like, core CDC59_RS03825 631f9fa798804830086d3bcd791a7f46 268 Pfam PF01609 Transposase DDE domain 100 254 2.4E-21 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS03825 631f9fa798804830086d3bcd791a7f46 268 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 11 83 1.1E-20 T 29-03-2018 IPR025161 Putative transposase IS4/IS5 family CDC59_RS11830 36271b17fa212bd17337227c430f660f 334 SUPERFAMILY SSF51735 115 295 6.46E-51 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS11830 36271b17fa212bd17337227c430f660f 334 Gene3D G3DSA:3.90.180.10 1 140 1.0E-34 T 29-03-2018 CDC59_RS11830 36271b17fa212bd17337227c430f660f 334 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 1 333 4.2E-145 T 29-03-2018 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 CDC59_RS11830 36271b17fa212bd17337227c430f660f 334 SUPERFAMILY SSF50129 1 143 1.46E-37 T 29-03-2018 IPR011032 GroES-like CDC59_RS11830 36271b17fa212bd17337227c430f660f 334 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 102 3.2E-6 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CDC59_RS11830 36271b17fa212bd17337227c430f660f 334 Gene3D G3DSA:3.40.50.720 141 300 1.8E-32 T 29-03-2018 CDC59_RS11830 36271b17fa212bd17337227c430f660f 334 Pfam PF00107 Zinc-binding dehydrogenase 160 281 1.2E-29 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CDC59_RS11830 36271b17fa212bd17337227c430f660f 334 SMART SM00829 10 331 1.3E-29 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CDC59_RS19920 675d3bed0c0defd5770b48725f685ef5 652 Pfam PF00593 TonB dependent receptor 250 650 9.2E-48 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CDC59_RS19920 675d3bed0c0defd5770b48725f685ef5 652 Pfam PF07715 TonB-dependent Receptor Plug Domain 42 153 1.0E-16 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CDC59_RS19920 675d3bed0c0defd5770b48725f685ef5 652 Gene3D G3DSA:2.40.170.20 164 650 3.1E-64 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CDC59_RS19920 675d3bed0c0defd5770b48725f685ef5 652 Gene3D G3DSA:2.170.130.10 21 163 3.8E-23 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CDC59_RS19920 675d3bed0c0defd5770b48725f685ef5 652 SUPERFAMILY SSF56935 30 650 3.66E-92 T 29-03-2018 CDC59_RS18145 176253188a2ed48226e6028748c15594 325 Pfam PF05229 Spore Coat Protein U domain 187 322 1.6E-31 T 29-03-2018 IPR007893 Spore coat protein U CDC59_RS18145 176253188a2ed48226e6028748c15594 325 Pfam PF05229 Spore Coat Protein U domain 25 161 8.8E-28 T 29-03-2018 IPR007893 Spore coat protein U CDC59_RS18145 176253188a2ed48226e6028748c15594 325 SMART SM00972 97 163 1.2E-10 T 29-03-2018 IPR007893 Spore coat protein U CDC59_RS18145 176253188a2ed48226e6028748c15594 325 SMART SM00972 263 322 1.9E-20 T 29-03-2018 IPR007893 Spore coat protein U CDC59_RS20025 39a6260614d5ad7df053a381486f4b5b 533 TIGRFAM TIGR03248 galactar-dH20: galactarate dehydratase 18 533 1.2E-290 T 29-03-2018 IPR017654 Galactarate dehydratase GarD-like GO:0008867|GO:0046392 KEGG: 00053+4.2.1.42|MetaCyc: PWY-6497 CDC59_RS20025 39a6260614d5ad7df053a381486f4b5b 533 SMART SM00858 26 96 2.7E-10 T 29-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 CDC59_RS20025 39a6260614d5ad7df053a381486f4b5b 533 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 123 531 8.1E-143 T 29-03-2018 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 CDC59_RS20025 39a6260614d5ad7df053a381486f4b5b 533 Pfam PF08666 SAF domain 27 96 8.2E-10 T 29-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 CDC59_RS04475 daf3f02ab4d093cc878f14b2418f2cf6 292 Pfam PF00483 Nucleotidyl transferase 3 239 9.3E-72 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CDC59_RS04475 daf3f02ab4d093cc878f14b2418f2cf6 292 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 3 287 1.6E-157 T 29-03-2018 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|KEGG: 00525+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 CDC59_RS04475 daf3f02ab4d093cc878f14b2418f2cf6 292 SUPERFAMILY SSF53448 2 287 1.24E-93 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDC59_RS04475 daf3f02ab4d093cc878f14b2418f2cf6 292 Gene3D G3DSA:3.90.550.10 3 292 5.4E-72 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDC59_RS05975 e50ec8dec5481d19ab4d44aa3ee85ae5 453 Gene3D G3DSA:1.10.40.30 375 445 2.3E-21 T 29-03-2018 CDC59_RS05975 e50ec8dec5481d19ab4d44aa3ee85ae5 453 TIGRFAM TIGR02426 protocat_pcaB: 3-carboxy-cis,cis-muconate cycloisomerase 5 348 4.8E-144 T 29-03-2018 IPR012789 3-carboxy-cis,cis-muconate cycloisomerase GO:0019619|GO:0047472 KEGG: 00362+5.5.1.2 CDC59_RS05975 e50ec8dec5481d19ab4d44aa3ee85ae5 453 Gene3D G3DSA:1.20.200.10 105 374 3.8E-81 T 29-03-2018 CDC59_RS05975 e50ec8dec5481d19ab4d44aa3ee85ae5 453 Pfam PF10397 Adenylosuccinate lyase C-terminus 364 444 4.7E-18 T 29-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CDC59_RS05975 e50ec8dec5481d19ab4d44aa3ee85ae5 453 ProSitePatterns PS00163 Fumarate lyases signature. 275 284 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CDC59_RS05975 e50ec8dec5481d19ab4d44aa3ee85ae5 453 SUPERFAMILY SSF48557 5 448 4.71E-112 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 CDC59_RS05975 e50ec8dec5481d19ab4d44aa3ee85ae5 453 SMART SM00998 363 445 4.9E-22 T 29-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CDC59_RS05975 e50ec8dec5481d19ab4d44aa3ee85ae5 453 PRINTS PR00145 Argininosuccinate lyase family signature 99 121 2.5E-6 T 29-03-2018 CDC59_RS05975 e50ec8dec5481d19ab4d44aa3ee85ae5 453 PRINTS PR00145 Argininosuccinate lyase family signature 140 160 2.5E-6 T 29-03-2018 CDC59_RS05975 e50ec8dec5481d19ab4d44aa3ee85ae5 453 PRINTS PR00145 Argininosuccinate lyase family signature 275 291 2.5E-6 T 29-03-2018 CDC59_RS05975 e50ec8dec5481d19ab4d44aa3ee85ae5 453 PRINTS PR00145 Argininosuccinate lyase family signature 230 254 2.5E-6 T 29-03-2018 CDC59_RS05975 e50ec8dec5481d19ab4d44aa3ee85ae5 453 Gene3D G3DSA:1.10.275.10 1 104 2.3E-18 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal CDC59_RS05975 e50ec8dec5481d19ab4d44aa3ee85ae5 453 Pfam PF00206 Lyase 11 300 3.8E-50 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal CDC59_RS05975 e50ec8dec5481d19ab4d44aa3ee85ae5 453 PRINTS PR00149 Fumarate lyase superfamily signature 275 291 2.0E-20 T 29-03-2018 IPR000362 Fumarate lyase family CDC59_RS05975 e50ec8dec5481d19ab4d44aa3ee85ae5 453 PRINTS PR00149 Fumarate lyase superfamily signature 145 163 2.0E-20 T 29-03-2018 IPR000362 Fumarate lyase family CDC59_RS05975 e50ec8dec5481d19ab4d44aa3ee85ae5 453 PRINTS PR00149 Fumarate lyase superfamily signature 100 118 2.0E-20 T 29-03-2018 IPR000362 Fumarate lyase family CDC59_RS05975 e50ec8dec5481d19ab4d44aa3ee85ae5 453 PRINTS PR00149 Fumarate lyase superfamily signature 230 257 2.0E-20 T 29-03-2018 IPR000362 Fumarate lyase family CDC59_RS11915 ccd7636557ced5c41436b4e2c41610f4 314 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 59 272 3.2E-10 T 29-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 CDC59_RS11915 ccd7636557ced5c41436b4e2c41610f4 314 SUPERFAMILY SSF56300 57 174 6.01E-33 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CDC59_RS11915 ccd7636557ced5c41436b4e2c41610f4 314 SUPERFAMILY SSF56300 233 298 6.01E-33 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CDC59_RS11915 ccd7636557ced5c41436b4e2c41610f4 314 Gene3D G3DSA:3.60.21.10 51 294 1.2E-25 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CDC59_RS13595 c75757412beb921c7bff6f36f0a04807 503 Pfam PF00795 Carbon-nitrogen hydrolase 240 466 3.3E-26 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CDC59_RS13595 c75757412beb921c7bff6f36f0a04807 503 Gene3D G3DSA:3.60.110.10 203 469 1.2E-37 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CDC59_RS13595 c75757412beb921c7bff6f36f0a04807 503 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 60 448 2.1E-117 T 29-03-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 CDC59_RS13595 c75757412beb921c7bff6f36f0a04807 503 SUPERFAMILY SSF56317 219 473 9.16E-35 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CDC59_RS13595 c75757412beb921c7bff6f36f0a04807 503 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 6 492 22.35 T 29-03-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 CDC59_RS08120 d99ae56f8b6cbd9dfadd5bfcd0cc7a53 376 Pfam PF04539 Sigma-70 region 3 220 297 5.9E-14 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS08120 d99ae56f8b6cbd9dfadd5bfcd0cc7a53 376 Pfam PF04542 Sigma-70 region 2 140 209 6.3E-20 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS08120 d99ae56f8b6cbd9dfadd5bfcd0cc7a53 376 Gene3D G3DSA:1.10.10.10 210 263 2.3E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS08120 d99ae56f8b6cbd9dfadd5bfcd0cc7a53 376 Pfam PF04545 Sigma-70, region 4 310 362 2.1E-16 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS08120 d99ae56f8b6cbd9dfadd5bfcd0cc7a53 376 SUPERFAMILY SSF88659 273 370 1.01E-25 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS08120 d99ae56f8b6cbd9dfadd5bfcd0cc7a53 376 SUPERFAMILY SSF88659 213 289 1.74E-10 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS08120 d99ae56f8b6cbd9dfadd5bfcd0cc7a53 376 Gene3D G3DSA:1.10.601.10 5 209 2.4E-61 T 29-03-2018 CDC59_RS08120 d99ae56f8b6cbd9dfadd5bfcd0cc7a53 376 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 335 361 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS08120 d99ae56f8b6cbd9dfadd5bfcd0cc7a53 376 Hamap MF_00959 RNA polymerase sigma factor RpoS [rpoS]. 70 376 38.433 T 29-03-2018 IPR012761 RNA polymerase sigma factor RpoS GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS08120 d99ae56f8b6cbd9dfadd5bfcd0cc7a53 376 TIGRFAM TIGR02394 rpoS_proteo: RNA polymerase sigma factor RpoS 93 375 1.8E-137 T 29-03-2018 IPR012761 RNA polymerase sigma factor RpoS GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS08120 d99ae56f8b6cbd9dfadd5bfcd0cc7a53 376 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 164 177 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS08120 d99ae56f8b6cbd9dfadd5bfcd0cc7a53 376 SUPERFAMILY SSF88946 102 210 4.32E-44 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS08120 d99ae56f8b6cbd9dfadd5bfcd0cc7a53 376 Gene3D G3DSA:1.10.10.10 304 373 9.9E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS08120 d99ae56f8b6cbd9dfadd5bfcd0cc7a53 376 PRINTS PR00046 Major sigma-70 factor signature 314 326 1.4E-23 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS08120 d99ae56f8b6cbd9dfadd5bfcd0cc7a53 376 PRINTS PR00046 Major sigma-70 factor signature 335 350 1.4E-23 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS08120 d99ae56f8b6cbd9dfadd5bfcd0cc7a53 376 PRINTS PR00046 Major sigma-70 factor signature 188 196 1.4E-23 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS08120 d99ae56f8b6cbd9dfadd5bfcd0cc7a53 376 PRINTS PR00046 Major sigma-70 factor signature 350 361 1.4E-23 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS08120 d99ae56f8b6cbd9dfadd5bfcd0cc7a53 376 PRINTS PR00046 Major sigma-70 factor signature 164 177 1.4E-23 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS08120 d99ae56f8b6cbd9dfadd5bfcd0cc7a53 376 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 136 364 3.8E-35 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS08120 d99ae56f8b6cbd9dfadd5bfcd0cc7a53 376 Pfam PF00140 Sigma-70 factor, region 1.2 102 135 2.4E-8 T 29-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS00655 97fc37f7107ed3556fb7cc70a92830ee 313 Gene3D G3DSA:1.10.800.10 9 313 1.6E-101 T 29-03-2018 IPR001273 Aromatic amino acid hydroxylase GO:0004497|GO:0005506|GO:0009072|GO:0055114 CDC59_RS00655 97fc37f7107ed3556fb7cc70a92830ee 313 ProSitePatterns PS00367 Biopterin-dependent aromatic amino acid hydroxylases signature. 150 161 - T 29-03-2018 IPR018301 Aromatic amino acid hydroxylase, iron/copper binding site GO:0004497|GO:0005506|GO:0009072|GO:0055114 CDC59_RS00655 97fc37f7107ed3556fb7cc70a92830ee 313 PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature 107 129 2.0E-10 T 29-03-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 CDC59_RS00655 97fc37f7107ed3556fb7cc70a92830ee 313 PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature 244 263 2.0E-10 T 29-03-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 CDC59_RS00655 97fc37f7107ed3556fb7cc70a92830ee 313 PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature 212 230 2.0E-10 T 29-03-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 CDC59_RS00655 97fc37f7107ed3556fb7cc70a92830ee 313 Pfam PF00351 Biopterin-dependent aromatic amino acid hydroxylase 48 266 6.6E-46 T 29-03-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 CDC59_RS00655 97fc37f7107ed3556fb7cc70a92830ee 313 SUPERFAMILY SSF56534 23 310 8.63E-109 T 29-03-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 CDC59_RS00655 97fc37f7107ed3556fb7cc70a92830ee 313 TIGRFAM TIGR01267 Phe4hydrox_mono: phenylalanine-4-hydroxylase 42 286 1.7E-116 T 29-03-2018 IPR005960 Phenylalanine-4-hydroxylase, monomeric form GO:0004505|GO:0006559|GO:0055114 KEGG: 00360+1.14.16.1|KEGG: 00400+1.14.16.1|MetaCyc: PWY-6134|MetaCyc: PWY-7158 CDC59_RS22945 4b4dbf3d3fe4d0921fbe499c92adc56a 421 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 84 407 5.7E-71 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 CDC59_RS22945 4b4dbf3d3fe4d0921fbe499c92adc56a 421 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 108 324 6.6E-29 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CDC59_RS22945 4b4dbf3d3fe4d0921fbe499c92adc56a 421 Gene3D G3DSA:3.90.1170.30 43 152 1.2E-6 T 29-03-2018 CDC59_RS22945 4b4dbf3d3fe4d0921fbe499c92adc56a 421 Gene3D G3DSA:1.10.287.470 153 203 3.0E-7 T 29-03-2018 CDC59_RS22945 4b4dbf3d3fe4d0921fbe499c92adc56a 421 SUPERFAMILY SSF111369 94 328 1.1E-35 T 29-03-2018 CDC59_RS22945 4b4dbf3d3fe4d0921fbe499c92adc56a 421 Gene3D G3DSA:2.40.50.100 213 406 1.9E-6 T 29-03-2018 CDC59_RS14095 e799a88c1e50a766fc72c702ec72033a 565 SUPERFAMILY SSF54637 468 556 5.71E-10 T 29-03-2018 IPR029069 HotDog domain CDC59_RS14095 e799a88c1e50a766fc72c702ec72033a 565 Gene3D G3DSA:3.40.50.980 133 291 4.7E-21 T 29-03-2018 CDC59_RS14095 e799a88c1e50a766fc72c702ec72033a 565 Pfam PF00501 AMP-binding enzyme 12 287 9.9E-16 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CDC59_RS14095 e799a88c1e50a766fc72c702ec72033a 565 Gene3D G3DSA:3.40.50.980 7 132 9.0E-5 T 29-03-2018 CDC59_RS14095 e799a88c1e50a766fc72c702ec72033a 565 Gene3D G3DSA:3.30.300.30 349 455 9.5E-15 T 29-03-2018 CDC59_RS14095 e799a88c1e50a766fc72c702ec72033a 565 Gene3D G3DSA:3.10.129.10 465 561 2.5E-11 T 29-03-2018 CDC59_RS14095 e799a88c1e50a766fc72c702ec72033a 565 SUPERFAMILY SSF56801 9 450 2.88E-44 T 29-03-2018 CDC59_RS23200 77e528ea83796967c15e271ad4f640d6 226 Pfam PF00072 Response regulator receiver domain 3 113 4.3E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS23200 77e528ea83796967c15e271ad4f640d6 226 Gene3D G3DSA:1.10.10.10 124 226 4.8E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS23200 77e528ea83796967c15e271ad4f640d6 226 SUPERFAMILY SSF52172 1 176 1.3E-42 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS23200 77e528ea83796967c15e271ad4f640d6 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 222 5.2E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDC59_RS23200 77e528ea83796967c15e271ad4f640d6 226 SMART SM00448 1 112 4.4E-42 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS23200 77e528ea83796967c15e271ad4f640d6 226 SMART SM00862 147 222 1.2E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDC59_RS23200 77e528ea83796967c15e271ad4f640d6 226 Gene3D G3DSA:3.40.50.2300 1 123 1.8E-37 T 29-03-2018 CDC59_RS09545 e526d700479de0ab3008083781d6d24b 1010 Pfam PF00912 Transglycosylase 131 325 9.5E-30 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 CDC59_RS09545 e526d700479de0ab3008083781d6d24b 1010 Gene3D G3DSA:1.10.3810.10 117 354 1.7E-28 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 CDC59_RS09545 e526d700479de0ab3008083781d6d24b 1010 Gene3D G3DSA:3.40.710.10 372 982 2.8E-55 T 29-03-2018 CDC59_RS09545 e526d700479de0ab3008083781d6d24b 1010 SUPERFAMILY SSF56601 713 980 2.84E-23 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CDC59_RS09545 e526d700479de0ab3008083781d6d24b 1010 SUPERFAMILY SSF53955 135 332 4.22E-10 T 29-03-2018 IPR023346 Lysozyme-like domain CDC59_RS09545 e526d700479de0ab3008083781d6d24b 1010 SUPERFAMILY SSF56601 571 679 3.1E-6 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CDC59_RS09545 e526d700479de0ab3008083781d6d24b 1010 SUPERFAMILY SSF56601 863 912 3.1E-6 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CDC59_RS09495 4c92e75405d798a3310932f0f05194f4 794 SUPERFAMILY SSF56003 138 789 4.71E-207 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CDC59_RS09495 4c92e75405d798a3310932f0f05194f4 794 SUPERFAMILY SSF54665 8 167 8.5E-46 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CDC59_RS09495 4c92e75405d798a3310932f0f05194f4 794 Gene3D G3DSA:3.30.365.10 488 610 4.7E-39 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CDC59_RS09495 4c92e75405d798a3310932f0f05194f4 794 SMART SM01008 26 146 3.0E-55 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CDC59_RS09495 4c92e75405d798a3310932f0f05194f4 794 Gene3D G3DSA:3.90.1170.50 3 146 9.1E-37 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CDC59_RS09495 4c92e75405d798a3310932f0f05194f4 794 Gene3D G3DSA:3.30.365.10 611 794 4.3E-52 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CDC59_RS09495 4c92e75405d798a3310932f0f05194f4 794 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 26 146 2.3E-30 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CDC59_RS09495 4c92e75405d798a3310932f0f05194f4 794 Gene3D G3DSA:3.30.365.10 287 447 8.1E-37 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CDC59_RS09495 4c92e75405d798a3310932f0f05194f4 794 Gene3D G3DSA:3.30.365.10 175 286 4.7E-27 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CDC59_RS09495 4c92e75405d798a3310932f0f05194f4 794 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 161 724 3.1E-179 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CDC59_RS15785 30232d5a65b87e2e9774f5da2e7b0e68 390 SMART SM00257 66 115 3.1E-5 T 29-03-2018 IPR018392 LysM domain CDC59_RS15785 30232d5a65b87e2e9774f5da2e7b0e68 390 Pfam PF01476 LysM domain 67 113 5.1E-13 T 29-03-2018 IPR018392 LysM domain CDC59_RS15785 30232d5a65b87e2e9774f5da2e7b0e68 390 Gene3D G3DSA:3.10.350.10 61 119 4.1E-15 T 29-03-2018 CDC59_RS15785 30232d5a65b87e2e9774f5da2e7b0e68 390 SUPERFAMILY SSF54106 66 115 3.79E-8 T 29-03-2018 IPR018392 LysM domain CDC59_RS08025 aec5168b05e91bbe871f0471a1c9d9fa 963 Gene3D G3DSA:3.40.50.300 279 646 3.9E-8 T 29-03-2018 CDC59_RS08025 aec5168b05e91bbe871f0471a1c9d9fa 963 Pfam PF12705 PD-(D/E)XK nuclease superfamily 689 943 2.8E-30 T 29-03-2018 CDC59_RS08025 aec5168b05e91bbe871f0471a1c9d9fa 963 Gene3D G3DSA:3.90.320.10 647 877 5.3E-12 T 29-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 CDC59_RS08025 aec5168b05e91bbe871f0471a1c9d9fa 963 SUPERFAMILY SSF52540 293 652 1.27E-31 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS02760 f2ed5b31f40e363179dddee4eec7fcf4 211 Gene3D G3DSA:1.20.120.80 26 211 1.1E-52 T 29-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS02760 f2ed5b31f40e363179dddee4eec7fcf4 211 Pfam PF00510 Cytochrome c oxidase subunit III 25 209 7.5E-17 T 29-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS02760 f2ed5b31f40e363179dddee4eec7fcf4 211 SUPERFAMILY SSF81452 17 209 2.35E-58 T 29-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS02760 f2ed5b31f40e363179dddee4eec7fcf4 211 TIGRFAM TIGR02842 CyoC: cytochrome o ubiquinol oxidase, subunit III 32 211 1.4E-83 T 29-03-2018 IPR014206 Cytochrome o ubiquinol oxidase, subunit III GO:0005886|GO:0008827|GO:0019646 CDC59_RS12205 edaae124ddbb7d8ed09f8a957e95a8e9 182 Gene3D G3DSA:2.60.40.200 33 182 4.3E-43 T 29-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CDC59_RS12205 edaae124ddbb7d8ed09f8a957e95a8e9 182 ProSitePatterns PS00087 Copper/Zinc superoxide dismutase signature 1. 78 88 - T 29-03-2018 IPR018152 Superoxide dismutase, copper/zinc, binding site GO:0004784|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CDC59_RS12205 edaae124ddbb7d8ed09f8a957e95a8e9 182 SUPERFAMILY SSF49329 37 179 6.54E-44 T 29-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CDC59_RS12205 edaae124ddbb7d8ed09f8a957e95a8e9 182 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 45 179 5.1E-42 T 29-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CDC59_RS12205 edaae124ddbb7d8ed09f8a957e95a8e9 182 ProSitePatterns PS00332 Copper/Zinc superoxide dismutase signature 2. 168 179 - T 29-03-2018 IPR018152 Superoxide dismutase, copper/zinc, binding site GO:0004784|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CDC59_RS12205 edaae124ddbb7d8ed09f8a957e95a8e9 182 PRINTS PR00068 Cu-Zn-superoxide dismutase family signature 78 100 4.9E-5 T 29-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CDC59_RS12205 edaae124ddbb7d8ed09f8a957e95a8e9 182 PRINTS PR00068 Cu-Zn-superoxide dismutase family signature 115 124 4.9E-5 T 29-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CDC59_RS12205 edaae124ddbb7d8ed09f8a957e95a8e9 182 PRINTS PR00068 Cu-Zn-superoxide dismutase family signature 135 157 4.9E-5 T 29-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CDC59_RS09720 b9f392bdad536294e904750bf88d978e 392 SUPERFAMILY SSF53901 1 264 3.19E-70 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS09720 b9f392bdad536294e904750bf88d978e 392 Gene3D G3DSA:3.40.47.10 1 267 8.9E-48 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS09720 b9f392bdad536294e904750bf88d978e 392 Pfam PF00108 Thiolase, N-terminal domain 5 260 5.0E-62 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CDC59_RS09720 b9f392bdad536294e904750bf88d978e 392 Gene3D G3DSA:3.40.47.10 268 389 2.9E-28 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS09720 b9f392bdad536294e904750bf88d978e 392 ProSitePatterns PS00737 Thiolases signature 2. 338 354 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CDC59_RS09720 b9f392bdad536294e904750bf88d978e 392 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 86 104 - T 29-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CDC59_RS09720 b9f392bdad536294e904750bf88d978e 392 PIRSF PIRSF000429 1 392 5.7E-116 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CDC59_RS09720 b9f392bdad536294e904750bf88d978e 392 Pfam PF02803 Thiolase, C-terminal domain 270 390 1.7E-44 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CDC59_RS09720 b9f392bdad536294e904750bf88d978e 392 SUPERFAMILY SSF53901 271 391 1.17E-41 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS09720 b9f392bdad536294e904750bf88d978e 392 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 390 1.8E-125 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CDC59_RS15000 47267c75ecda2d3a5d1cf57e6ffdc907 674 Pfam PF02785 Biotin carboxylase C-terminal domain 336 455 1.2E-33 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CDC59_RS15000 47267c75ecda2d3a5d1cf57e6ffdc907 674 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 322 7.4E-77 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CDC59_RS15000 47267c75ecda2d3a5d1cf57e6ffdc907 674 SMART SM00878 336 455 5.9E-55 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CDC59_RS15000 47267c75ecda2d3a5d1cf57e6ffdc907 674 SUPERFAMILY SSF51246 331 461 1.67E-37 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CDC59_RS15000 47267c75ecda2d3a5d1cf57e6ffdc907 674 SUPERFAMILY SSF56059 83 348 1.77E-69 T 29-03-2018 CDC59_RS15000 47267c75ecda2d3a5d1cf57e6ffdc907 674 Gene3D G3DSA:3.30.1490.20 124 209 6.6E-21 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CDC59_RS15000 47267c75ecda2d3a5d1cf57e6ffdc907 674 Gene3D G3DSA:3.30.470.20 210 458 1.2E-104 T 29-03-2018 CDC59_RS15000 47267c75ecda2d3a5d1cf57e6ffdc907 674 Pfam PF00364 Biotin-requiring enzyme 604 667 3.3E-16 T 29-03-2018 IPR000089 Biotin/lipoyl attachment CDC59_RS15000 47267c75ecda2d3a5d1cf57e6ffdc907 674 SUPERFAMILY SSF52440 1 113 3.45E-47 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CDC59_RS15000 47267c75ecda2d3a5d1cf57e6ffdc907 674 Gene3D G3DSA:3.40.50.20 1 123 1.1E-51 T 29-03-2018 CDC59_RS15000 47267c75ecda2d3a5d1cf57e6ffdc907 674 Gene3D G3DSA:2.40.50.100 600 672 1.1E-17 T 29-03-2018 CDC59_RS15000 47267c75ecda2d3a5d1cf57e6ffdc907 674 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 2.8E-43 T 29-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CDC59_RS15000 47267c75ecda2d3a5d1cf57e6ffdc907 674 SUPERFAMILY SSF51230 590 669 7.07E-20 T 29-03-2018 IPR011053 Single hybrid motif CDC59_RS15000 47267c75ecda2d3a5d1cf57e6ffdc907 674 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CDC59_RS15000 47267c75ecda2d3a5d1cf57e6ffdc907 674 SMART SM01209 114 293 0.0026 T 29-03-2018 CDC59_RS15000 47267c75ecda2d3a5d1cf57e6ffdc907 674 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CDC59_RS18295 230c92cc3466d05348d6659224c54875 142 SUPERFAMILY SSF55718 23 132 1.88E-18 T 29-03-2018 IPR003033 SCP2 sterol-binding domain CDC59_RS18295 230c92cc3466d05348d6659224c54875 142 Pfam PF02036 SCP-2 sterol transfer family 48 126 3.8E-11 T 29-03-2018 IPR003033 SCP2 sterol-binding domain CDC59_RS18295 230c92cc3466d05348d6659224c54875 142 Gene3D G3DSA:3.30.1050.10 7 134 2.5E-12 T 29-03-2018 IPR003033 SCP2 sterol-binding domain CDC59_RS16820 afeccfcf8ee102f04e757ae5b74c85b8 194 SUPERFAMILY SSF160904 15 191 1.16E-48 T 29-03-2018 CDC59_RS16820 afeccfcf8ee102f04e757ae5b74c85b8 194 Pfam PF07336 Putative stress-induced transcription regulator 17 145 1.9E-21 T 29-03-2018 IPR010852 Putative stress-induced transcription regulator CDC59_RS16820 afeccfcf8ee102f04e757ae5b74c85b8 194 Gene3D G3DSA:1.10.3300.10 10 194 3.1E-51 T 29-03-2018 IPR023286 ABATE domain CDC59_RS16820 afeccfcf8ee102f04e757ae5b74c85b8 194 Pfam PF11706 CGNR zinc finger 149 192 3.8E-19 T 29-03-2018 IPR021005 Zinc finger, CGNR CDC59_RS03075 88bca0d22c7a8366adafe97473a296d9 390 Pfam PF13609 Gram-negative porin 7 340 3.0E-54 T 29-03-2018 CDC59_RS03075 88bca0d22c7a8366adafe97473a296d9 390 Gene3D G3DSA:2.40.160.10 9 390 2.8E-73 T 29-03-2018 CDC59_RS03075 88bca0d22c7a8366adafe97473a296d9 390 SUPERFAMILY SSF56935 21 390 3.36E-83 T 29-03-2018 CDC59_RS09280 cbe461617addd03c838eaed4c003c71a 179 Pfam PF13511 Domain of unknown function (DUF4124) 14 73 3.0E-8 T 29-03-2018 IPR025392 Domain of unknown function DUF4124 CDC59_RS05915 328d77e25c74e0cf8173c59aeab36dfb 456 Pfam PF16933 Putative exopolysaccharide Exporter (EPS-E) 1 453 2.0E-168 T 29-03-2018 IPR031617 Putative exopolysaccharide exporter CDC59_RS10215 c812f5f7c23a79d353934b4916a49cc8 402 SUPERFAMILY SSF111369 72 300 3.14E-25 T 29-03-2018 CDC59_RS10215 c812f5f7c23a79d353934b4916a49cc8 402 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 84 298 3.2E-27 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CDC59_RS10215 c812f5f7c23a79d353934b4916a49cc8 402 Gene3D G3DSA:1.10.287.470 140 184 2.5E-8 T 29-03-2018 CDC59_RS10215 c812f5f7c23a79d353934b4916a49cc8 402 Gene3D G3DSA:2.40.50.100 84 139 1.4E-16 T 29-03-2018 CDC59_RS10215 c812f5f7c23a79d353934b4916a49cc8 402 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 59 384 1.4E-74 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 CDC59_RS10215 c812f5f7c23a79d353934b4916a49cc8 402 Gene3D G3DSA:2.40.50.100 186 388 3.0E-8 T 29-03-2018 CDC59_RS22175 63d4db3351240faee9095e68fdf8e245 769 SUPERFAMILY SSF142764 11 409 3.53E-77 T 29-03-2018 CDC59_RS22175 63d4db3351240faee9095e68fdf8e245 769 Pfam PF17042 Putative nucleotide-binding of sugar-metabolising enzyme 253 402 4.4E-19 T 29-03-2018 IPR031475 Putative nucleotide-binding C-terminal domain CDC59_RS22175 63d4db3351240faee9095e68fdf8e245 769 Gene3D G3DSA:3.40.50.10840 10 237 2.4E-50 T 29-03-2018 IPR010737 Putative sugar-binding, N-terminal domain CDC59_RS22175 63d4db3351240faee9095e68fdf8e245 769 Gene3D G3DSA:3.40.718.10 420 760 4.1E-130 T 29-03-2018 CDC59_RS22175 63d4db3351240faee9095e68fdf8e245 769 Hamap MF_00536 4-hydroxythreonine-4-phosphate dehydrogenase [pdxA]. 432 757 34.726 T 29-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 CDC59_RS22175 63d4db3351240faee9095e68fdf8e245 769 SUPERFAMILY SSF53659 434 759 2.73E-107 T 29-03-2018 CDC59_RS22175 63d4db3351240faee9095e68fdf8e245 769 Pfam PF07005 Putative sugar-binding N-terminal domain 11 227 1.6E-46 T 29-03-2018 IPR010737 Putative sugar-binding, N-terminal domain CDC59_RS22175 63d4db3351240faee9095e68fdf8e245 769 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 436 757 2.5E-108 T 29-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 CDC59_RS22175 63d4db3351240faee9095e68fdf8e245 769 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 463 753 2.2E-101 T 29-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 CDC59_RS21540 31dd6ca14138ecaa95cc2646f055a6cc 513 Gene3D G3DSA:1.10.287.950 203 321 2.6E-18 T 29-03-2018 CDC59_RS21540 31dd6ca14138ecaa95cc2646f055a6cc 513 Gene3D G3DSA:1.10.287.950 322 513 5.0E-48 T 29-03-2018 CDC59_RS21540 31dd6ca14138ecaa95cc2646f055a6cc 513 SMART SM01049 33 127 6.7E-37 T 29-03-2018 IPR033480 Single Cache domain 2 CDC59_RS21540 31dd6ca14138ecaa95cc2646f055a6cc 513 SMART SM00283 265 512 1.5E-89 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CDC59_RS21540 31dd6ca14138ecaa95cc2646f055a6cc 513 Gene3D G3DSA:3.30.450.20 27 189 6.3E-49 T 29-03-2018 CDC59_RS21540 31dd6ca14138ecaa95cc2646f055a6cc 513 Pfam PF17200 Single Cache domain 2 37 184 2.3E-42 T 29-03-2018 IPR033480 Single Cache domain 2 CDC59_RS21540 31dd6ca14138ecaa95cc2646f055a6cc 513 SUPERFAMILY SSF58104 248 513 1.12E-68 T 29-03-2018 CDC59_RS21540 31dd6ca14138ecaa95cc2646f055a6cc 513 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 324 479 5.4E-52 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CDC59_RS01975 d8455913b1a9fae07ed3d7be56b55fec 268 SUPERFAMILY SSF51182 17 185 1.16E-19 T 29-03-2018 IPR011051 RmlC-like cupin domain CDC59_RS01975 d8455913b1a9fae07ed3d7be56b55fec 268 Pfam PF02311 AraC-like ligand binding domain 25 140 2.3E-16 T 29-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CDC59_RS01975 d8455913b1a9fae07ed3d7be56b55fec 268 Pfam PF12833 Helix-turn-helix domain 182 259 2.3E-22 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CDC59_RS01975 d8455913b1a9fae07ed3d7be56b55fec 268 Gene3D G3DSA:2.60.120.10 4 136 3.5E-9 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CDC59_RS01975 d8455913b1a9fae07ed3d7be56b55fec 268 SMART SM00342 176 258 3.2E-25 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CDC59_RS01975 d8455913b1a9fae07ed3d7be56b55fec 268 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 242 258 3.2E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CDC59_RS01975 d8455913b1a9fae07ed3d7be56b55fec 268 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 227 242 3.2E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CDC59_RS01975 d8455913b1a9fae07ed3d7be56b55fec 268 Gene3D G3DSA:1.10.10.60 158 216 7.8E-11 T 29-03-2018 CDC59_RS01975 d8455913b1a9fae07ed3d7be56b55fec 268 Gene3D G3DSA:1.10.10.60 217 264 2.8E-11 T 29-03-2018 CDC59_RS01975 d8455913b1a9fae07ed3d7be56b55fec 268 SUPERFAMILY SSF46689 217 259 6.72E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS07380 c4ab50a738067ba5e4cecb2a73e1587d 272 TIGRFAM TIGR00613 reco: DNA repair protein RecO 42 187 6.8E-28 T 29-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CDC59_RS07380 c4ab50a738067ba5e4cecb2a73e1587d 272 Pfam PF02565 Recombination protein O C terminal 121 263 3.0E-18 T 29-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CDC59_RS07380 c4ab50a738067ba5e4cecb2a73e1587d 272 Pfam PF11967 Recombination protein O N terminal 41 114 1.9E-25 T 29-03-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal CDC59_RS07380 c4ab50a738067ba5e4cecb2a73e1587d 272 Gene3D G3DSA:2.40.50.140 37 118 1.6E-27 T 29-03-2018 CDC59_RS07380 c4ab50a738067ba5e4cecb2a73e1587d 272 Hamap MF_00201 DNA repair protein RecO [recO]. 38 269 22.653 T 29-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CDC59_RS07380 c4ab50a738067ba5e4cecb2a73e1587d 272 SUPERFAMILY SSF57863 125 207 1.33E-9 T 29-03-2018 CDC59_RS07380 c4ab50a738067ba5e4cecb2a73e1587d 272 SUPERFAMILY SSF50249 39 113 1.46E-16 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDC59_RS09650 184f3a2667b572cfd7b2873caff695ef 205 Pfam PF08768 Domain of unknown function (DUF1794) 26 201 5.6E-21 T 29-03-2018 IPR014878 Domain of unknown function DUF1794 CDC59_RS09650 184f3a2667b572cfd7b2873caff695ef 205 PIRSF PIRSF036226 1 205 5.8E-101 T 29-03-2018 IPR014602 Uncharacterised conserved protein UCP036226 CDC59_RS09650 184f3a2667b572cfd7b2873caff695ef 205 Gene3D G3DSA:2.40.128.20 23 205 4.2E-26 T 29-03-2018 IPR012674 Calycin CDC59_RS09650 184f3a2667b572cfd7b2873caff695ef 205 SUPERFAMILY SSF50814 26 201 1.26E-23 T 29-03-2018 IPR012674 Calycin CDC59_RS22655 e57af7d0cc21aba595c54ed7c9a994e9 710 Gene3D G3DSA:3.40.50.300 12 320 3.0E-51 T 29-03-2018 CDC59_RS22655 e57af7d0cc21aba595c54ed7c9a994e9 710 Gene3D G3DSA:3.40.50.300 321 424 5.1E-18 T 29-03-2018 CDC59_RS22655 e57af7d0cc21aba595c54ed7c9a994e9 710 Pfam PF13361 UvrD-like helicase C-terminal domain 318 471 3.9E-19 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CDC59_RS22655 e57af7d0cc21aba595c54ed7c9a994e9 710 Pfam PF13361 UvrD-like helicase C-terminal domain 566 640 7.0E-17 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CDC59_RS22655 e57af7d0cc21aba595c54ed7c9a994e9 710 Gene3D G3DSA:3.40.50.300 433 672 1.6E-30 T 29-03-2018 CDC59_RS22655 e57af7d0cc21aba595c54ed7c9a994e9 710 SUPERFAMILY SSF52540 13 648 1.16E-123 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS22655 e57af7d0cc21aba595c54ed7c9a994e9 710 Pfam PF00580 UvrD/REP helicase N-terminal domain 38 310 4.2E-53 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CDC59_RS10300 06c19431d4c6dc490d9efc9040d65f72 394 SUPERFAMILY SSF53901 271 393 3.78E-44 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS10300 06c19431d4c6dc490d9efc9040d65f72 394 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 392 5.7E-140 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CDC59_RS10300 06c19431d4c6dc490d9efc9040d65f72 394 SUPERFAMILY SSF53901 4 271 1.2E-82 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS10300 06c19431d4c6dc490d9efc9040d65f72 394 Pfam PF02803 Thiolase, C-terminal domain 271 393 1.1E-46 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CDC59_RS10300 06c19431d4c6dc490d9efc9040d65f72 394 PIRSF PIRSF000429 1 394 2.0E-129 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CDC59_RS10300 06c19431d4c6dc490d9efc9040d65f72 394 Pfam PF00108 Thiolase, N-terminal domain 5 264 1.1E-90 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CDC59_RS10300 06c19431d4c6dc490d9efc9040d65f72 394 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 86 104 - T 29-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CDC59_RS10300 06c19431d4c6dc490d9efc9040d65f72 394 Gene3D G3DSA:3.40.47.10 267 391 2.6E-35 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS10300 06c19431d4c6dc490d9efc9040d65f72 394 ProSitePatterns PS00099 Thiolases active site. 375 388 - T 29-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CDC59_RS10300 06c19431d4c6dc490d9efc9040d65f72 394 Gene3D G3DSA:3.40.47.10 184 266 5.5E-24 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS10300 06c19431d4c6dc490d9efc9040d65f72 394 Gene3D G3DSA:3.40.47.10 1 183 8.5E-31 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS11570 d1acc64e4aff39478c917b4fbf962d73 502 Gene3D G3DSA:1.10.1040.10 183 286 4.1E-27 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CDC59_RS11570 d1acc64e4aff39478c917b4fbf962d73 502 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 411 492 4.1E-18 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CDC59_RS11570 d1acc64e4aff39478c917b4fbf962d73 502 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 184 281 4.4E-27 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CDC59_RS11570 d1acc64e4aff39478c917b4fbf962d73 502 Gene3D G3DSA:1.10.1040.10 411 496 1.5E-16 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CDC59_RS11570 d1acc64e4aff39478c917b4fbf962d73 502 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 4 181 2.4E-60 T 29-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CDC59_RS11570 d1acc64e4aff39478c917b4fbf962d73 502 SUPERFAMILY SSF51735 2 182 1.56E-52 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS11570 d1acc64e4aff39478c917b4fbf962d73 502 SUPERFAMILY SSF48179 411 494 1.19E-19 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CDC59_RS11570 d1acc64e4aff39478c917b4fbf962d73 502 SUPERFAMILY SSF48179 183 289 4.42E-30 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CDC59_RS11570 d1acc64e4aff39478c917b4fbf962d73 502 Gene3D G3DSA:3.40.50.720 3 182 5.1E-51 T 29-03-2018 CDC59_RS22160 fcdcc532b52fdfe93fe2ffddd926a392 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 2.8E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDC59_RS22160 fcdcc532b52fdfe93fe2ffddd926a392 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 2.8E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDC59_RS22160 fcdcc532b52fdfe93fe2ffddd926a392 218 Gene3D G3DSA:1.10.10.60 2 67 6.1E-18 T 29-03-2018 CDC59_RS22160 fcdcc532b52fdfe93fe2ffddd926a392 218 SUPERFAMILY SSF46689 15 77 1.99E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS22160 fcdcc532b52fdfe93fe2ffddd926a392 218 Gene3D G3DSA:1.10.357.10 77 217 5.3E-11 T 29-03-2018 CDC59_RS22160 fcdcc532b52fdfe93fe2ffddd926a392 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 67 9.1E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDC59_RS06440 910b0e47c7660446b4b352428eaf08d7 340 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 166 178 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CDC59_RS06440 910b0e47c7660446b4b352428eaf08d7 340 SMART SM00220 24 298 1.6E-32 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CDC59_RS06440 910b0e47c7660446b4b352428eaf08d7 340 Gene3D G3DSA:1.10.510.10 125 333 4.0E-35 T 29-03-2018 CDC59_RS06440 910b0e47c7660446b4b352428eaf08d7 340 Gene3D G3DSA:3.30.200.20 17 124 1.7E-19 T 29-03-2018 CDC59_RS06440 910b0e47c7660446b4b352428eaf08d7 340 Pfam PF00069 Protein kinase domain 24 289 6.8E-37 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CDC59_RS06440 910b0e47c7660446b4b352428eaf08d7 340 SUPERFAMILY SSF56112 21 297 5.26E-55 T 29-03-2018 IPR011009 Protein kinase-like domain CDC59_RS08630 7ba57730800a614eea2e1d62c00e2ae1 577 SUPERFAMILY SSF53187 99 276 1.57E-45 T 29-03-2018 CDC59_RS08630 7ba57730800a614eea2e1d62c00e2ae1 577 SUPERFAMILY SSF53187 489 572 1.57E-45 T 29-03-2018 CDC59_RS08630 7ba57730800a614eea2e1d62c00e2ae1 577 Pfam PF07687 Peptidase dimerisation domain 352 470 2.9E-6 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CDC59_RS08630 7ba57730800a614eea2e1d62c00e2ae1 577 SUPERFAMILY SSF55031 276 472 9.27E-42 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CDC59_RS08630 7ba57730800a614eea2e1d62c00e2ae1 577 Gene3D G3DSA:3.40.630.10 95 284 2.9E-22 T 29-03-2018 CDC59_RS08630 7ba57730800a614eea2e1d62c00e2ae1 577 Gene3D G3DSA:3.30.70.360 383 474 1.5E-22 T 29-03-2018 CDC59_RS08630 7ba57730800a614eea2e1d62c00e2ae1 577 Gene3D G3DSA:3.30.70.360 295 382 1.9E-11 T 29-03-2018 CDC59_RS08630 7ba57730800a614eea2e1d62c00e2ae1 577 Pfam PF01546 Peptidase family M20/M25/M40 169 567 3.5E-23 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CDC59_RS08630 7ba57730800a614eea2e1d62c00e2ae1 577 TIGRFAM TIGR01887 dipeptidaselike: putative dipeptidase 102 565 4.8E-79 T 29-03-2018 IPR010964 Peptidase M20A, peptidase V-related GO:0008270|GO:0016805 CDC59_RS01080 e9162a919c3e0314eb41950dd80c7e83 90 Gene3D G3DSA:3.30.2310.20 6 90 8.7E-13 T 29-03-2018 CDC59_RS01080 e9162a919c3e0314eb41950dd80c7e83 90 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 8 85 2.1E-5 T 29-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family CDC59_RS01080 e9162a919c3e0314eb41950dd80c7e83 90 SUPERFAMILY SSF143011 8 85 4.12E-16 T 29-03-2018 IPR035095 Toxin RelE-like domain CDC59_RS08370 ce33efd08733e943f656f044d429c050 1331 Gene3D G3DSA:3.40.50.300 70 233 6.3E-29 T 29-03-2018 CDC59_RS08370 ce33efd08733e943f656f044d429c050 1331 SMART SM00847 469 559 1.4E-37 T 29-03-2018 IPR007502 Helicase-associated domain GO:0004386 CDC59_RS08370 ce33efd08733e943f656f044d429c050 1331 Pfam PF00271 Helicase conserved C-terminal domain 291 408 5.1E-11 T 29-03-2018 IPR001650 Helicase, C-terminal CDC59_RS08370 ce33efd08733e943f656f044d429c050 1331 SMART SM00490 309 409 1.4E-15 T 29-03-2018 IPR001650 Helicase, C-terminal CDC59_RS08370 ce33efd08733e943f656f044d429c050 1331 TIGRFAM TIGR01967 DEAH_box_HrpA: RNA helicase HrpA 46 1327 0.0 T 29-03-2018 IPR010222 RNA helicase HrpA GO:0004004 CDC59_RS08370 ce33efd08733e943f656f044d429c050 1331 Pfam PF11898 Domain of unknown function (DUF3418) 717 1327 4.9E-220 T 29-03-2018 IPR024590 RNA helicase HrpA, C-terminal CDC59_RS08370 ce33efd08733e943f656f044d429c050 1331 Pfam PF07717 Oligonucleotide/oligosaccharide-binding (OB)-fold 623 703 7.3E-13 T 29-03-2018 IPR011709 Domain of unknown function DUF1605 CDC59_RS08370 ce33efd08733e943f656f044d429c050 1331 Gene3D G3DSA:3.40.50.300 258 427 3.6E-45 T 29-03-2018 CDC59_RS08370 ce33efd08733e943f656f044d429c050 1331 SMART SM00487 69 264 9.9E-24 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CDC59_RS08370 ce33efd08733e943f656f044d429c050 1331 Pfam PF04408 Helicase associated domain (HA2) 472 557 2.4E-21 T 29-03-2018 IPR007502 Helicase-associated domain GO:0004386 CDC59_RS08370 ce33efd08733e943f656f044d429c050 1331 Pfam PF00270 DEAD/DEAH box helicase 80 231 2.0E-5 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CDC59_RS08370 ce33efd08733e943f656f044d429c050 1331 SMART SM00382 86 375 1.8E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS08370 ce33efd08733e943f656f044d429c050 1331 SUPERFAMILY SSF52540 68 587 1.23E-100 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS08670 ee2d92adfe7d128fd876fa47e1c6f7af 108 SUPERFAMILY SSF50249 10 101 1.99E-14 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDC59_RS08670 ee2d92adfe7d128fd876fa47e1c6f7af 108 Gene3D G3DSA:2.40.50.140 6 105 0.0011 T 29-03-2018 CDC59_RS08670 ee2d92adfe7d128fd876fa47e1c6f7af 108 Hamap MF_00720 Primosomal replication protein N [priB]. 10 105 21.937 T 29-03-2018 IPR023646 Primosomal replication protein PriB GO:0003697|GO:0006260|GO:0030894 CDC59_RS08670 ee2d92adfe7d128fd876fa47e1c6f7af 108 PIRSF PIRSF003135 6 105 2.5E-12 T 29-03-2018 IPR023646 Primosomal replication protein PriB GO:0003697|GO:0006260|GO:0030894 CDC59_RS08670 ee2d92adfe7d128fd876fa47e1c6f7af 108 TIGRFAM TIGR04418 PriB_gamma: primosomal replication protein PriB 11 103 8.9E-30 T 29-03-2018 IPR023646 Primosomal replication protein PriB GO:0003697|GO:0006260|GO:0030894 CDC59_RS08465 1fb83dbb7226705b5273fd5fb4ec25d3 953 PIRSF PIRSF000157 1 945 0.0 T 29-03-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CDC59_RS08465 1fb83dbb7226705b5273fd5fb4ec25d3 953 SMART SM00861 600 797 1.5E-62 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CDC59_RS08465 1fb83dbb7226705b5273fd5fb4ec25d3 953 SUPERFAMILY SSF52518 583 804 1.09E-49 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CDC59_RS08465 1fb83dbb7226705b5273fd5fb4ec25d3 953 Pfam PF00676 Dehydrogenase E1 component 217 520 1.7E-47 T 29-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 CDC59_RS08465 1fb83dbb7226705b5273fd5fb4ec25d3 953 Gene3D G3DSA:3.40.50.970 597 809 8.7E-59 T 29-03-2018 CDC59_RS08465 1fb83dbb7226705b5273fd5fb4ec25d3 953 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 11 49 9.7E-16 T 29-03-2018 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CDC59_RS08465 1fb83dbb7226705b5273fd5fb4ec25d3 953 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 13 942 0.0 T 29-03-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CDC59_RS08465 1fb83dbb7226705b5273fd5fb4ec25d3 953 Gene3D G3DSA:1.10.287.1150 87 171 7.2E-22 T 29-03-2018 CDC59_RS08465 1fb83dbb7226705b5273fd5fb4ec25d3 953 SUPERFAMILY SSF52518 125 552 3.53E-87 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CDC59_RS08465 1fb83dbb7226705b5273fd5fb4ec25d3 953 Pfam PF02779 Transketolase, pyrimidine binding domain 600 796 4.5E-65 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CDC59_RS08465 1fb83dbb7226705b5273fd5fb4ec25d3 953 Gene3D G3DSA:3.40.50.970 172 530 2.4E-84 T 29-03-2018 CDC59_RS08465 1fb83dbb7226705b5273fd5fb4ec25d3 953 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 802 943 1.9E-53 T 29-03-2018 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CDC59_RS21420 e1c2aa7674b2c9751ff31cf354cdc7d7 384 SUPERFAMILY SSF51735 19 178 7.13E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS21420 e1c2aa7674b2c9751ff31cf354cdc7d7 384 PRINTS PR01775 Bacterial glucose-fructose oxidoreductase signature 317 333 4.4E-12 T 29-03-2018 IPR008354 Glucose-fructose oxidoreductase, bacterial MetaCyc: PWY-5530 CDC59_RS21420 e1c2aa7674b2c9751ff31cf354cdc7d7 384 PRINTS PR01775 Bacterial glucose-fructose oxidoreductase signature 74 90 4.4E-12 T 29-03-2018 IPR008354 Glucose-fructose oxidoreductase, bacterial MetaCyc: PWY-5530 CDC59_RS21420 e1c2aa7674b2c9751ff31cf354cdc7d7 384 PRINTS PR01775 Bacterial glucose-fructose oxidoreductase signature 136 150 4.4E-12 T 29-03-2018 IPR008354 Glucose-fructose oxidoreductase, bacterial MetaCyc: PWY-5530 CDC59_RS21420 e1c2aa7674b2c9751ff31cf354cdc7d7 384 PRINTS PR01775 Bacterial glucose-fructose oxidoreductase signature 265 280 4.4E-12 T 29-03-2018 IPR008354 Glucose-fructose oxidoreductase, bacterial MetaCyc: PWY-5530 CDC59_RS21420 e1c2aa7674b2c9751ff31cf354cdc7d7 384 PRINTS PR01775 Bacterial glucose-fructose oxidoreductase signature 22 35 4.4E-12 T 29-03-2018 IPR008354 Glucose-fructose oxidoreductase, bacterial MetaCyc: PWY-5530 CDC59_RS21420 e1c2aa7674b2c9751ff31cf354cdc7d7 384 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 24 146 2.1E-24 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CDC59_RS21420 e1c2aa7674b2c9751ff31cf354cdc7d7 384 SUPERFAMILY SSF55347 152 317 4.25E-32 T 29-03-2018 CDC59_RS21420 e1c2aa7674b2c9751ff31cf354cdc7d7 384 Gene3D G3DSA:3.30.360.10 156 358 3.7E-40 T 29-03-2018 CDC59_RS21420 e1c2aa7674b2c9751ff31cf354cdc7d7 384 Gene3D G3DSA:3.40.50.720 7 155 1.1E-31 T 29-03-2018 CDC59_RS08290 ad755d3ac08cbcd06d96fe30bfea9c7a 281 SUPERFAMILY SSF51658 9 273 1.93E-57 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CDC59_RS08290 ad755d3ac08cbcd06d96fe30bfea9c7a 281 Gene3D G3DSA:3.20.20.150 3 275 4.8E-31 T 29-03-2018 CDC59_RS08290 ad755d3ac08cbcd06d96fe30bfea9c7a 281 Pfam PF01261 Xylose isomerase-like TIM barrel 29 225 1.1E-14 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CDC59_RS08290 ad755d3ac08cbcd06d96fe30bfea9c7a 281 PIRSF PIRSF036778 1 278 3.1E-111 T 29-03-2018 IPR014621 Uncharacterised conserved protein UCP036778, sugar epimerase-type CDC59_RS02720 3aee6eb485de83b47997b9a96c6f86e5 432 SUPERFAMILY SSF55874 280 429 3.14E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS02720 3aee6eb485de83b47997b9a96c6f86e5 432 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 326 430 2.9E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS02720 3aee6eb485de83b47997b9a96c6f86e5 432 Gene3D G3DSA:3.30.565.10 264 432 1.8E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS02720 3aee6eb485de83b47997b9a96c6f86e5 432 SUPERFAMILY SSF47384 202 274 3.14E-6 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS02720 3aee6eb485de83b47997b9a96c6f86e5 432 PRINTS PR00344 Bacterial sensor protein C-terminal signature 362 376 2.0E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS02720 3aee6eb485de83b47997b9a96c6f86e5 432 PRINTS PR00344 Bacterial sensor protein C-terminal signature 392 410 2.0E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS02720 3aee6eb485de83b47997b9a96c6f86e5 432 PRINTS PR00344 Bacterial sensor protein C-terminal signature 380 390 2.0E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS02720 3aee6eb485de83b47997b9a96c6f86e5 432 PRINTS PR00344 Bacterial sensor protein C-terminal signature 416 429 2.0E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS02720 3aee6eb485de83b47997b9a96c6f86e5 432 SMART SM00387 323 432 1.4E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS02720 3aee6eb485de83b47997b9a96c6f86e5 432 Gene3D G3DSA:1.10.287.130 198 263 1.3E-4 T 29-03-2018 CDC59_RS01600 0cf73fbe7733a1a6823749025ac9f3be 416 Pfam PF07690 Major Facilitator Superfamily 30 272 2.2E-13 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDC59_RS01600 0cf73fbe7733a1a6823749025ac9f3be 416 Gene3D G3DSA:1.20.1250.20 11 207 1.8E-14 T 29-03-2018 CDC59_RS01600 0cf73fbe7733a1a6823749025ac9f3be 416 SUPERFAMILY SSF103473 12 399 7.19E-38 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS01600 0cf73fbe7733a1a6823749025ac9f3be 416 Gene3D G3DSA:1.20.1250.20 209 399 2.0E-12 T 29-03-2018 CDC59_RS03795 8c8af337ced7a2eb754696551cec5ae8 442 Gene3D G3DSA:3.50.50.60 25 424 8.4E-25 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS03795 8c8af337ced7a2eb754696551cec5ae8 442 SUPERFAMILY SSF51905 356 416 1.38E-33 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS03795 8c8af337ced7a2eb754696551cec5ae8 442 SUPERFAMILY SSF51905 35 258 1.38E-33 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS03795 8c8af337ced7a2eb754696551cec5ae8 442 Pfam PF01266 FAD dependent oxidoreductase 37 396 1.2E-39 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CDC59_RS06575 7fa7e9ce02acb957fc510eb15f1488cc 245 Gene3D G3DSA:3.40.50.720 1 194 9.1E-50 T 29-03-2018 CDC59_RS06575 7fa7e9ce02acb957fc510eb15f1488cc 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 5.7E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS06575 7fa7e9ce02acb957fc510eb15f1488cc 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 5.7E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS06575 7fa7e9ce02acb957fc510eb15f1488cc 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 5.7E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS06575 7fa7e9ce02acb957fc510eb15f1488cc 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 5.7E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS06575 7fa7e9ce02acb957fc510eb15f1488cc 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 5.7E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS06575 7fa7e9ce02acb957fc510eb15f1488cc 245 Pfam PF00106 short chain dehydrogenase 6 193 8.3E-49 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS06575 7fa7e9ce02acb957fc510eb15f1488cc 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 1.2E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS06575 7fa7e9ce02acb957fc510eb15f1488cc 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 1.2E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS06575 7fa7e9ce02acb957fc510eb15f1488cc 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 1.2E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS06575 7fa7e9ce02acb957fc510eb15f1488cc 245 SUPERFAMILY SSF51735 1 226 5.13E-55 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS06575 7fa7e9ce02acb957fc510eb15f1488cc 245 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 186 2.0E-5 T 29-03-2018 CDC59_RS06575 7fa7e9ce02acb957fc510eb15f1488cc 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CDC59_RS02265 4688fa07a053468140e20088b33da9ee 264 Gene3D G3DSA:3.30.1140.32 108 208 3.3E-37 T 29-03-2018 CDC59_RS02265 4688fa07a053468140e20088b33da9ee 264 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 206 38.561 T 29-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 CDC59_RS02265 4688fa07a053468140e20088b33da9ee 264 SUPERFAMILY SSF54821 108 206 1.83E-39 T 29-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS02265 4688fa07a053468140e20088b33da9ee 264 Pfam PF07650 KH domain 38 110 4.1E-21 T 29-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS02265 4688fa07a053468140e20088b33da9ee 264 Gene3D G3DSA:3.30.300.20 17 107 1.3E-27 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CDC59_RS02265 4688fa07a053468140e20088b33da9ee 264 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 209 3.8E-92 T 29-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 CDC59_RS02265 4688fa07a053468140e20088b33da9ee 264 Pfam PF00189 Ribosomal protein S3, C-terminal domain 120 202 1.4E-40 T 29-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS02265 4688fa07a053468140e20088b33da9ee 264 ProSitePatterns PS00548 Ribosomal protein S3 signature. 163 197 - T 29-03-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS02265 4688fa07a053468140e20088b33da9ee 264 SMART SM00322 60 125 7.3E-8 T 29-03-2018 IPR004087 K Homology domain GO:0003676 CDC59_RS02265 4688fa07a053468140e20088b33da9ee 264 SUPERFAMILY SSF54814 2 106 1.86E-36 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CDC59_RS17565 7c62248acb4955b9d7e7bca656f69c0c 320 PRINTS PR00111 Alpha/beta hydrolase fold signature 123 136 5.8E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS17565 7c62248acb4955b9d7e7bca656f69c0c 320 PRINTS PR00111 Alpha/beta hydrolase fold signature 63 78 5.8E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS17565 7c62248acb4955b9d7e7bca656f69c0c 320 PRINTS PR00111 Alpha/beta hydrolase fold signature 109 122 5.8E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS17565 7c62248acb4955b9d7e7bca656f69c0c 320 TIGRFAM TIGR01249 pro_imino_pep_1: prolyl aminopeptidase 12 314 7.4E-115 T 29-03-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 CDC59_RS17565 7c62248acb4955b9d7e7bca656f69c0c 320 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 40 48 5.4E-14 T 29-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CDC59_RS17565 7c62248acb4955b9d7e7bca656f69c0c 320 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 109 123 5.4E-14 T 29-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CDC59_RS17565 7c62248acb4955b9d7e7bca656f69c0c 320 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 66 77 5.4E-14 T 29-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CDC59_RS17565 7c62248acb4955b9d7e7bca656f69c0c 320 Gene3D G3DSA:3.40.50.1820 1 317 5.7E-64 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS17565 7c62248acb4955b9d7e7bca656f69c0c 320 Pfam PF00561 alpha/beta hydrolase fold 41 296 2.1E-27 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS17565 7c62248acb4955b9d7e7bca656f69c0c 320 PIRSF PIRSF006431 3 318 6.5E-131 T 29-03-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 CDC59_RS17565 7c62248acb4955b9d7e7bca656f69c0c 320 SUPERFAMILY SSF53474 4 299 3.02E-62 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS23015 bc3f703643c3b2f4100450715c0e8ae8 361 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 8 356 2.2E-81 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CDC59_RS23015 bc3f703643c3b2f4100450715c0e8ae8 361 Gene3D G3DSA:3.40.718.10 215 361 4.3E-49 T 29-03-2018 CDC59_RS23015 bc3f703643c3b2f4100450715c0e8ae8 361 Gene3D G3DSA:3.40.718.10 1 214 9.0E-66 T 29-03-2018 CDC59_RS23015 bc3f703643c3b2f4100450715c0e8ae8 361 TIGRFAM TIGR02089 TTC: tartrate dehydrogenase 4 359 1.1E-156 T 29-03-2018 IPR011829 Tartrate dehydrogenase GO:0016616|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.93|KEGG: 00650+1.1.1.83 CDC59_RS23015 bc3f703643c3b2f4100450715c0e8ae8 361 SMART SM01329 7 356 2.1E-164 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CDC59_RS23015 bc3f703643c3b2f4100450715c0e8ae8 361 SUPERFAMILY SSF53659 4 360 2.11E-110 T 29-03-2018 CDC59_RS20785 5d3c0763c81b54b3b4497da2a68aebe5 395 PIRSF PIRSF000390 3 390 1.0E-115 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CDC59_RS20785 5d3c0763c81b54b3b4497da2a68aebe5 395 Gene3D G3DSA:3.90.1150.10 251 395 4.4E-32 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS20785 5d3c0763c81b54b3b4497da2a68aebe5 395 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 14 380 2.5E-96 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CDC59_RS20785 5d3c0763c81b54b3b4497da2a68aebe5 395 SUPERFAMILY SSF53383 7 381 5.71E-105 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS20785 5d3c0763c81b54b3b4497da2a68aebe5 395 Gene3D G3DSA:3.40.640.10 7 250 5.0E-45 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDC59_RS18315 2cb91d34864dd603e9d780f74992bbba 685 SUPERFAMILY SSF51998 120 652 8.24E-153 T 29-03-2018 CDC59_RS18315 2cb91d34864dd603e9d780f74992bbba 685 Pfam PF03477 ATP cone domain 5 90 5.2E-20 T 29-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 CDC59_RS18315 2cb91d34864dd603e9d780f74992bbba 685 Gene3D G3DSA:3.20.70.20 128 663 1.4E-183 T 29-03-2018 CDC59_RS18315 2cb91d34864dd603e9d780f74992bbba 685 TIGRFAM TIGR02487 NrdD: anaerobic ribonucleoside-triphosphate reductase 119 651 3.4E-135 T 29-03-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2 CDC59_RS18315 2cb91d34864dd603e9d780f74992bbba 685 Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase 120 650 5.5E-169 T 29-03-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2 CDC59_RS14845 c7111a5487b7af5a559c41102d5cfb93 905 PIRSF PIRSF000381 1 878 0.0 T 29-03-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CDC59_RS14845 c7111a5487b7af5a559c41102d5cfb93 905 SMART SM01018 320 407 7.6E-43 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CDC59_RS14845 c7111a5487b7af5a559c41102d5cfb93 905 SUPERFAMILY SSF47644 315 406 2.09E-27 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CDC59_RS14845 c7111a5487b7af5a559c41102d5cfb93 905 TIGRFAM TIGR02082 metH: methionine synthase 5 875 0.0 T 29-03-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CDC59_RS14845 c7111a5487b7af5a559c41102d5cfb93 905 SUPERFAMILY SSF52242 416 572 7.98E-43 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CDC59_RS14845 c7111a5487b7af5a559c41102d5cfb93 905 Gene3D G3DSA:3.20.20.20 11 309 2.5E-76 T 29-03-2018 CDC59_RS14845 c7111a5487b7af5a559c41102d5cfb93 905 SUPERFAMILY SSF51717 22 296 2.88E-91 T 29-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CDC59_RS14845 c7111a5487b7af5a559c41102d5cfb93 905 Gene3D G3DSA:1.10.288.10 694 766 1.0E-18 T 29-03-2018 CDC59_RS14845 c7111a5487b7af5a559c41102d5cfb93 905 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 615 890 9.1E-117 T 29-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CDC59_RS14845 c7111a5487b7af5a559c41102d5cfb93 905 Pfam PF02310 B12 binding domain 422 515 3.7E-16 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CDC59_RS14845 c7111a5487b7af5a559c41102d5cfb93 905 Gene3D G3DSA:3.10.196.10 767 905 1.3E-53 T 29-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CDC59_RS14845 c7111a5487b7af5a559c41102d5cfb93 905 Gene3D G3DSA:1.10.1240.10 310 407 7.1E-37 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CDC59_RS14845 c7111a5487b7af5a559c41102d5cfb93 905 Pfam PF02607 B12 binding domain 322 399 1.1E-25 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CDC59_RS14845 c7111a5487b7af5a559c41102d5cfb93 905 Gene3D G3DSA:3.40.50.280 417 573 1.1E-53 T 29-03-2018 CDC59_RS14845 c7111a5487b7af5a559c41102d5cfb93 905 SUPERFAMILY SSF56507 579 905 3.01E-121 T 29-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CDC59_RS14845 c7111a5487b7af5a559c41102d5cfb93 905 Gene3D G3DSA:1.10.288.10 616 672 1.3E-21 T 29-03-2018 CDC59_RS14845 c7111a5487b7af5a559c41102d5cfb93 905 Pfam PF00809 Pterin binding enzyme 26 264 3.8E-61 T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CDC59_RS12125 e217feb160bf033975f693d37866fe86 442 SUPERFAMILY SSF103473 24 438 9.29E-80 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS12125 e217feb160bf033975f693d37866fe86 442 Gene3D G3DSA:1.20.1250.20 24 233 4.4E-33 T 29-03-2018 CDC59_RS12125 e217feb160bf033975f693d37866fe86 442 Gene3D G3DSA:1.20.1250.20 244 440 6.8E-22 T 29-03-2018 CDC59_RS12125 e217feb160bf033975f693d37866fe86 442 Pfam PF07690 Major Facilitator Superfamily 39 401 5.3E-42 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDC59_RS20745 c2b59bc6ab6cf04847ff4477d0d9ac33 197 SUPERFAMILY SSF144091 3 192 1.14E-38 T 29-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CDC59_RS20745 c2b59bc6ab6cf04847ff4477d0d9ac33 197 Pfam PF01694 Rhomboid family 44 192 1.0E-34 T 29-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CDC59_RS20745 c2b59bc6ab6cf04847ff4477d0d9ac33 197 Gene3D G3DSA:1.20.1540.10 1 193 8.0E-43 T 29-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CDC59_RS15235 a15f1534da798844e2071cf74a865982 196 Pfam PF08281 Sigma-70, region 4 111 163 5.9E-15 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS15235 a15f1534da798844e2071cf74a865982 196 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 164 2.3E-19 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS15235 a15f1534da798844e2071cf74a865982 196 SUPERFAMILY SSF88946 4 75 4.32E-6 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS15235 a15f1534da798844e2071cf74a865982 196 Gene3D G3DSA:1.10.10.10 108 172 2.0E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS15235 a15f1534da798844e2071cf74a865982 196 Gene3D G3DSA:1.10.1740.10 3 82 1.4E-7 T 29-03-2018 CDC59_RS15235 a15f1534da798844e2071cf74a865982 196 SUPERFAMILY SSF88659 103 168 4.3E-15 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS05540 b3912709a0de95b3b0ed51dedae03acc 307 Gene3D G3DSA:3.40.800.20 1 307 8.3E-113 T 29-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CDC59_RS05540 b3912709a0de95b3b0ed51dedae03acc 307 Pfam PF00850 Histone deacetylase domain 20 304 3.7E-84 T 29-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CDC59_RS05540 b3912709a0de95b3b0ed51dedae03acc 307 SUPERFAMILY SSF52768 2 306 1.44E-107 T 29-03-2018 CDC59_RS05540 b3912709a0de95b3b0ed51dedae03acc 307 PRINTS PR01270 Histone deacetylase superfamily signature 234 244 3.7E-17 T 29-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CDC59_RS05540 b3912709a0de95b3b0ed51dedae03acc 307 PRINTS PR01270 Histone deacetylase superfamily signature 122 145 3.7E-17 T 29-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CDC59_RS05540 b3912709a0de95b3b0ed51dedae03acc 307 PRINTS PR01270 Histone deacetylase superfamily signature 156 171 3.7E-17 T 29-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CDC59_RS02490 96fb7c840eefb263ea1164473100ff8c 387 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 41 382 2.1E-86 T 29-03-2018 IPR006261 dNTP triphosphohydrolase GO:0016793 CDC59_RS02490 96fb7c840eefb263ea1164473100ff8c 387 Gene3D G3DSA:1.10.3210.10 31 384 5.6E-84 T 29-03-2018 CDC59_RS02490 96fb7c840eefb263ea1164473100ff8c 387 Pfam PF13286 Phosphohydrolase-associated domain 294 380 7.6E-28 T 29-03-2018 IPR026875 Phosphohydrolase-associated domain CDC59_RS02490 96fb7c840eefb263ea1164473100ff8c 387 SUPERFAMILY SSF109604 29 382 4.26E-92 T 29-03-2018 CDC59_RS02490 96fb7c840eefb263ea1164473100ff8c 387 Pfam PF01966 HD domain 78 208 1.1E-15 T 29-03-2018 IPR006674 HD domain CDC59_RS02490 96fb7c840eefb263ea1164473100ff8c 387 SMART SM00471 74 218 7.2E-11 T 29-03-2018 IPR003607 HD/PDEase domain CDC59_RS02490 96fb7c840eefb263ea1164473100ff8c 387 Hamap MF_01212 Deoxyguanosinetriphosphate triphosphohydrolase-like protein. 18 382 38.613 T 29-03-2018 IPR023023 dNTP triphosphohydrolase, type 2 GO:0016793 CDC59_RS08470 fcecb08062018c1ae3460cba7fa0353d 405 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 175 403 5.3E-80 T 29-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CDC59_RS08470 fcecb08062018c1ae3460cba7fa0353d 405 Pfam PF02817 e3 binding domain 103 136 1.4E-10 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CDC59_RS08470 fcecb08062018c1ae3460cba7fa0353d 405 Gene3D G3DSA:4.10.320.10 97 157 1.7E-14 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CDC59_RS08470 fcecb08062018c1ae3460cba7fa0353d 405 SUPERFAMILY SSF52777 175 404 5.78E-88 T 29-03-2018 CDC59_RS08470 fcecb08062018c1ae3460cba7fa0353d 405 SUPERFAMILY SSF51230 2 96 4.71E-27 T 29-03-2018 IPR011053 Single hybrid motif CDC59_RS08470 fcecb08062018c1ae3460cba7fa0353d 405 Gene3D G3DSA:2.40.50.100 6 65 2.5E-14 T 29-03-2018 CDC59_RS08470 fcecb08062018c1ae3460cba7fa0353d 405 Gene3D G3DSA:3.90.1170.30 66 96 0.26 T 29-03-2018 CDC59_RS08470 fcecb08062018c1ae3460cba7fa0353d 405 Gene3D G3DSA:3.30.559.10 160 403 1.0E-88 T 29-03-2018 CDC59_RS08470 fcecb08062018c1ae3460cba7fa0353d 405 SUPERFAMILY SSF47005 101 140 1.83E-9 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CDC59_RS08470 fcecb08062018c1ae3460cba7fa0353d 405 Pfam PF00364 Biotin-requiring enzyme 5 77 3.5E-21 T 29-03-2018 IPR000089 Biotin/lipoyl attachment CDC59_RS08470 fcecb08062018c1ae3460cba7fa0353d 405 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 28 57 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CDC59_RS08470 fcecb08062018c1ae3460cba7fa0353d 405 TIGRFAM TIGR01347 sucB: dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex 4 404 1.5E-160 T 29-03-2018 IPR006255 Dihydrolipoamide succinyltransferase GO:0004149|GO:0006099|GO:0045252 KEGG: 00020+2.3.1.61|KEGG: 00310+2.3.1.61|MetaCyc: PWY-5084|Reactome: R-HSA-389661|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CDC59_RS13150 7e8c93d8304080c69b7fed4b319e2a52 183 SUPERFAMILY SSF46689 3 85 1.65E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS13150 7e8c93d8304080c69b7fed4b319e2a52 183 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 6.2E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDC59_RS13150 7e8c93d8304080c69b7fed4b319e2a52 183 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 6.2E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDC59_RS13150 7e8c93d8304080c69b7fed4b319e2a52 183 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 59 7.8E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDC59_RS13150 7e8c93d8304080c69b7fed4b319e2a52 183 Gene3D G3DSA:1.10.10.60 47 180 6.7E-7 T 29-03-2018 CDC59_RS13150 7e8c93d8304080c69b7fed4b319e2a52 183 Gene3D G3DSA:1.10.10.60 1 46 2.6E-16 T 29-03-2018 CDC59_RS12575 81d757192c63d31c2a6357d2c74df2eb 56 SUPERFAMILY SSF57829 3 54 4.33E-19 T 29-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CDC59_RS12575 81d757192c63d31c2a6357d2c74df2eb 56 Pfam PF00471 Ribosomal protein L33 9 54 3.3E-18 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS12575 81d757192c63d31c2a6357d2c74df2eb 56 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 6 54 14.62 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS12575 81d757192c63d31c2a6357d2c74df2eb 56 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 56 3.9E-27 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS12575 81d757192c63d31c2a6357d2c74df2eb 56 ProSitePatterns PS00582 Ribosomal protein L33 signature. 22 41 - T 29-03-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS06195 c2ad4cb866c31868a557e5f54f826d42 232 PIRSF PIRSF006232 1 230 1.1E-55 T 29-03-2018 IPR012093 Pirin Reactome: R-HSA-8935690 CDC59_RS06195 c2ad4cb866c31868a557e5f54f826d42 232 Pfam PF02678 Pirin 6 119 4.1E-37 T 29-03-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 CDC59_RS06195 c2ad4cb866c31868a557e5f54f826d42 232 SUPERFAMILY SSF51182 1 231 1.76E-76 T 29-03-2018 IPR011051 RmlC-like cupin domain CDC59_RS06195 c2ad4cb866c31868a557e5f54f826d42 232 Gene3D G3DSA:2.60.120.10 132 232 2.0E-29 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CDC59_RS06195 c2ad4cb866c31868a557e5f54f826d42 232 Gene3D G3DSA:2.60.120.10 12 131 2.0E-50 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CDC59_RS15435 72f4921f1d0d807d1966ccff5531ca16 321 Pfam PF03466 LysR substrate binding domain 97 297 7.9E-26 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS15435 72f4921f1d0d807d1966ccff5531ca16 321 Gene3D G3DSA:3.40.190.10 183 268 1.2E-17 T 29-03-2018 CDC59_RS15435 72f4921f1d0d807d1966ccff5531ca16 321 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 67 5.7E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS15435 72f4921f1d0d807d1966ccff5531ca16 321 Gene3D G3DSA:3.40.190.10 95 182 2.3E-15 T 29-03-2018 CDC59_RS15435 72f4921f1d0d807d1966ccff5531ca16 321 Gene3D G3DSA:1.10.10.10 3 87 5.4E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS15435 72f4921f1d0d807d1966ccff5531ca16 321 SUPERFAMILY SSF46785 5 86 1.5E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS15435 72f4921f1d0d807d1966ccff5531ca16 321 SUPERFAMILY SSF53850 90 295 4.89E-41 T 29-03-2018 CDC59_RS15435 72f4921f1d0d807d1966ccff5531ca16 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 2.4E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS15435 72f4921f1d0d807d1966ccff5531ca16 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 2.4E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS15435 72f4921f1d0d807d1966ccff5531ca16 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 2.4E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS18195 29e42970fc7043fdef383b361cf23e44 607 Gene3D G3DSA:3.40.50.1820 112 393 1.9E-7 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS18195 29e42970fc7043fdef383b361cf23e44 607 PIRSF PIRSF029063 107 300 2.2E-32 T 29-03-2018 IPR011225 Type IV secretory pathway, VirJ component CDC59_RS18195 29e42970fc7043fdef383b361cf23e44 607 PIRSF PIRSF029063 366 606 5.3E-86 T 29-03-2018 IPR011225 Type IV secretory pathway, VirJ component CDC59_RS18195 29e42970fc7043fdef383b361cf23e44 607 Gene3D G3DSA:3.40.50.1820 394 571 3.5E-18 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS18195 29e42970fc7043fdef383b361cf23e44 607 Pfam PF06057 Bacterial virulence protein (VirJ) 414 600 5.0E-81 T 29-03-2018 IPR010333 Bacterial virulence CDC59_RS18195 29e42970fc7043fdef383b361cf23e44 607 SUPERFAMILY SSF53474 138 265 1.58E-7 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS18195 29e42970fc7043fdef383b361cf23e44 607 SUPERFAMILY SSF53474 398 597 2.88E-22 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS12805 55a3ce0a732ee51c5b19cd4b7c66c5ef 493 SMART SM00478 322 484 1.5E-8 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CDC59_RS12805 55a3ce0a732ee51c5b19cd4b7c66c5ef 493 SMART SM00342 100 183 2.0E-25 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CDC59_RS12805 55a3ce0a732ee51c5b19cd4b7c66c5ef 493 Pfam PF02805 Metal binding domain of Ada 7 71 7.4E-30 T 29-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 CDC59_RS12805 55a3ce0a732ee51c5b19cd4b7c66c5ef 493 Gene3D G3DSA:1.10.10.60 85 139 2.8E-10 T 29-03-2018 CDC59_RS12805 55a3ce0a732ee51c5b19cd4b7c66c5ef 493 SUPERFAMILY SSF46689 137 186 3.58E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS12805 55a3ce0a732ee51c5b19cd4b7c66c5ef 493 SUPERFAMILY SSF48150 302 483 3.49E-38 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CDC59_RS12805 55a3ce0a732ee51c5b19cd4b7c66c5ef 493 Pfam PF12833 Helix-turn-helix domain 106 185 1.7E-20 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CDC59_RS12805 55a3ce0a732ee51c5b19cd4b7c66c5ef 493 Gene3D G3DSA:1.10.340.30 301 444 7.9E-27 T 29-03-2018 CDC59_RS12805 55a3ce0a732ee51c5b19cd4b7c66c5ef 493 SUPERFAMILY SSF46689 86 133 2.96E-6 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS12805 55a3ce0a732ee51c5b19cd4b7c66c5ef 493 SUPERFAMILY SSF57884 2 76 1.44E-32 T 29-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 CDC59_RS12805 55a3ce0a732ee51c5b19cd4b7c66c5ef 493 SMART SM01009 197 312 5.1E-55 T 29-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal CDC59_RS12805 55a3ce0a732ee51c5b19cd4b7c66c5ef 493 Gene3D G3DSA:3.40.10.10 1 73 1.6E-26 T 29-03-2018 IPR035451 Ada-like domain CDC59_RS12805 55a3ce0a732ee51c5b19cd4b7c66c5ef 493 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 137 179 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CDC59_RS12805 55a3ce0a732ee51c5b19cd4b7c66c5ef 493 Gene3D G3DSA:1.10.10.60 140 189 1.0E-10 T 29-03-2018 CDC59_RS12805 55a3ce0a732ee51c5b19cd4b7c66c5ef 493 Gene3D G3DSA:1.10.1670.10 445 484 1.1E-12 T 29-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CDC59_RS12805 55a3ce0a732ee51c5b19cd4b7c66c5ef 493 SUPERFAMILY SSF55945 197 297 5.49E-30 T 29-03-2018 CDC59_RS12805 55a3ce0a732ee51c5b19cd4b7c66c5ef 493 Pfam PF06029 AlkA N-terminal domain 197 312 1.0E-36 T 29-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal CDC59_RS12805 55a3ce0a732ee51c5b19cd4b7c66c5ef 493 Gene3D G3DSA:3.30.310.20 197 300 1.5E-35 T 29-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal CDC59_RS05460 e93f80bac91a662c1fa8145de682974d 378 SUPERFAMILY SSF53383 14 375 1.64E-116 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS05460 e93f80bac91a662c1fa8145de682974d 378 Gene3D G3DSA:3.40.640.10 27 275 3.5E-34 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDC59_RS05460 e93f80bac91a662c1fa8145de682974d 378 PIRSF PIRSF000525 9 378 1.5E-156 T 29-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 CDC59_RS05460 e93f80bac91a662c1fa8145de682974d 378 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 13 377 50.777 T 29-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 CDC59_RS05460 e93f80bac91a662c1fa8145de682974d 378 Pfam PF00266 Aminotransferase class-V 15 366 3.6E-52 T 29-03-2018 IPR000192 Aminotransferase class V domain CDC59_RS05460 e93f80bac91a662c1fa8145de682974d 378 TIGRFAM TIGR01364 serC_1: phosphoserine transaminase 15 375 5.3E-152 T 29-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 CDC59_RS05460 e93f80bac91a662c1fa8145de682974d 378 Gene3D G3DSA:3.90.1150.10 276 376 1.5E-37 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS09195 bdb99545aac8c9c5d27ce027a459b18f 184 SUPERFAMILY SSF111384 37 178 3.14E-36 T 29-03-2018 IPR024930 Skp domain CDC59_RS09195 bdb99545aac8c9c5d27ce027a459b18f 184 Gene3D G3DSA:3.30.910.20 26 100 8.3E-11 T 29-03-2018 CDC59_RS09195 bdb99545aac8c9c5d27ce027a459b18f 184 Gene3D G3DSA:3.30.910.20 101 178 1.4E-15 T 29-03-2018 CDC59_RS09195 bdb99545aac8c9c5d27ce027a459b18f 184 SMART SM00935 26 178 1.2E-59 T 29-03-2018 IPR005632 Chaperone protein Skp GO:0051082 CDC59_RS09195 bdb99545aac8c9c5d27ce027a459b18f 184 Pfam PF03938 Outer membrane protein (OmpH-like) 24 177 3.8E-37 T 29-03-2018 IPR005632 Chaperone protein Skp GO:0051082 CDC59_RS09195 bdb99545aac8c9c5d27ce027a459b18f 184 PIRSF PIRSF002094 13 181 1.2E-49 T 29-03-2018 IPR005632 Chaperone protein Skp GO:0051082 CDC59_RS16740 d16d187647a92e1eade14106643d3b22 825 TIGRFAM TIGR03939 PGA_TPR_OMP: poly-beta-1,6 N-acetyl-D-glucosamine export porin PgaA 208 823 4.4E-128 T 29-03-2018 IPR023870 Poly-beta-1,6 N-acetyl-D-glucosamine export porin PgaA GO:0022891|GO:0042710 CDC59_RS16740 d16d187647a92e1eade14106643d3b22 825 SUPERFAMILY SSF48452 309 408 1.16E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS16740 d16d187647a92e1eade14106643d3b22 825 Gene3D G3DSA:1.25.40.10 276 555 1.4E-21 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS16740 d16d187647a92e1eade14106643d3b22 825 SUPERFAMILY SSF48452 383 509 4.14E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS14150 6e67bbd7d2e8609904ab005a64992df3 271 SUPERFAMILY SSF46689 173 221 8.06E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS14150 6e67bbd7d2e8609904ab005a64992df3 271 SUPERFAMILY SSF51215 23 155 9.94E-22 T 29-03-2018 CDC59_RS14150 6e67bbd7d2e8609904ab005a64992df3 271 Gene3D G3DSA:2.60.120.10 14 88 5.7E-6 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CDC59_RS14150 6e67bbd7d2e8609904ab005a64992df3 271 Gene3D G3DSA:1.10.10.60 104 224 1.3E-11 T 29-03-2018 CDC59_RS14150 6e67bbd7d2e8609904ab005a64992df3 271 Gene3D G3DSA:1.10.10.60 225 271 2.5E-15 T 29-03-2018 CDC59_RS14150 6e67bbd7d2e8609904ab005a64992df3 271 Pfam PF02311 AraC-like ligand binding domain 14 149 2.8E-26 T 29-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CDC59_RS14150 6e67bbd7d2e8609904ab005a64992df3 271 Pfam PF12833 Helix-turn-helix domain 193 270 2.7E-22 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CDC59_RS14150 6e67bbd7d2e8609904ab005a64992df3 271 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 254 270 6.2E-8 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CDC59_RS14150 6e67bbd7d2e8609904ab005a64992df3 271 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 239 254 6.2E-8 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CDC59_RS14150 6e67bbd7d2e8609904ab005a64992df3 271 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 224 266 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CDC59_RS14150 6e67bbd7d2e8609904ab005a64992df3 271 SMART SM00342 187 270 5.1E-30 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CDC59_RS14150 6e67bbd7d2e8609904ab005a64992df3 271 SUPERFAMILY SSF46689 223 270 2.06E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS03945 1a6f6d3c120b1154f597550da1090855 381 SUPERFAMILY SSF56176 15 179 3.88E-33 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CDC59_RS03945 1a6f6d3c120b1154f597550da1090855 381 SUPERFAMILY SSF55103 142 377 1.05E-20 T 29-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CDC59_RS03945 1a6f6d3c120b1154f597550da1090855 381 Gene3D G3DSA:1.10.45.10 346 378 3.6E-7 T 29-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CDC59_RS03945 1a6f6d3c120b1154f597550da1090855 381 Gene3D G3DSA:3.30.465.10 53 178 3.8E-26 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CDC59_RS03945 1a6f6d3c120b1154f597550da1090855 381 Pfam PF01565 FAD binding domain 14 141 4.5E-21 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CDC59_RS08055 b960ffa5929660680b4ea4b3ce28ca98 207 Pfam PF02132 RecR protein 45 83 2.4E-16 T 29-03-2018 IPR023628 Recombination protein RecR, C4-type zinc finger CDC59_RS08055 b960ffa5929660680b4ea4b3ce28ca98 207 SUPERFAMILY SSF111304 9 207 9.68E-74 T 29-03-2018 IPR023627 Recombination protein RecR CDC59_RS08055 b960ffa5929660680b4ea4b3ce28ca98 207 Pfam PF13662 Toprim domain 85 180 3.1E-22 T 29-03-2018 IPR006171 TOPRIM domain CDC59_RS08055 b960ffa5929660680b4ea4b3ce28ca98 207 Gene3D G3DSA:3.40.1360.10 82 179 1.0E-33 T 29-03-2018 CDC59_RS08055 b960ffa5929660680b4ea4b3ce28ca98 207 TIGRFAM TIGR00615 recR: recombination protein RecR 9 205 3.4E-70 T 29-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 CDC59_RS08055 b960ffa5929660680b4ea4b3ce28ca98 207 Hamap MF_00017 Recombination protein RecR [recR]. 1 207 97.865 T 29-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 CDC59_RS08055 b960ffa5929660680b4ea4b3ce28ca98 207 SMART SM00493 85 174 2.0E-10 T 29-03-2018 IPR006171 TOPRIM domain CDC59_RS10680 805760dad57840410f02b05657c76db9 140 PRINTS PR01727 Prokaryotic integration host factor signature 113 127 6.4E-13 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CDC59_RS10680 805760dad57840410f02b05657c76db9 140 PRINTS PR01727 Prokaryotic integration host factor signature 79 94 6.4E-13 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CDC59_RS10680 805760dad57840410f02b05657c76db9 140 PRINTS PR01727 Prokaryotic integration host factor signature 97 110 6.4E-13 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CDC59_RS10680 805760dad57840410f02b05657c76db9 140 SMART SM00411 40 129 5.3E-41 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CDC59_RS10680 805760dad57840410f02b05657c76db9 140 SUPERFAMILY SSF47729 40 129 3.68E-31 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CDC59_RS10680 805760dad57840410f02b05657c76db9 140 TIGRFAM TIGR00987 himA: integration host factor, alpha subunit 39 131 3.5E-43 T 29-03-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 CDC59_RS10680 805760dad57840410f02b05657c76db9 140 Pfam PF00216 Bacterial DNA-binding protein 40 128 1.7E-29 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CDC59_RS10680 805760dad57840410f02b05657c76db9 140 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 85 104 - T 29-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 CDC59_RS10680 805760dad57840410f02b05657c76db9 140 Gene3D G3DSA:4.10.520.10 38 134 1.3E-31 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CDC59_RS10680 805760dad57840410f02b05657c76db9 140 Hamap MF_00380 Integration host factor subunit alpha [ihfA]. 38 134 29.889 T 29-03-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 CDC59_RS04140 d2d01ffa920e59a8d44a3ba4d64fff11 169 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 5 132 2.8E-33 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CDC59_RS04140 d2d01ffa920e59a8d44a3ba4d64fff11 169 SUPERFAMILY SSF55083 1 141 5.49E-48 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CDC59_RS04140 d2d01ffa920e59a8d44a3ba4d64fff11 169 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 4 132 1.7E-36 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CDC59_RS04140 d2d01ffa920e59a8d44a3ba4d64fff11 169 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 87 98 - T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CDC59_RS04140 d2d01ffa920e59a8d44a3ba4d64fff11 169 Gene3D G3DSA:3.30.70.560 1 168 5.5E-51 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CDC59_RS06280 3ec76b62b1cc19970a813f5d7ebdcc8c 422 Gene3D G3DSA:3.30.470.20 189 327 1.3E-59 T 29-03-2018 CDC59_RS06280 3ec76b62b1cc19970a813f5d7ebdcc8c 422 SUPERFAMILY SSF51246 327 420 5.57E-31 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CDC59_RS06280 3ec76b62b1cc19970a813f5d7ebdcc8c 422 SUPERFAMILY SSF52440 1 101 3.88E-34 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CDC59_RS06280 3ec76b62b1cc19970a813f5d7ebdcc8c 422 SMART SM01209 101 294 1.9E-135 T 29-03-2018 CDC59_RS06280 3ec76b62b1cc19970a813f5d7ebdcc8c 422 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 100 9.1E-35 T 29-03-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CDC59_RS06280 3ec76b62b1cc19970a813f5d7ebdcc8c 422 Gene3D G3DSA:3.30.1490.20 85 187 3.4E-23 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CDC59_RS06280 3ec76b62b1cc19970a813f5d7ebdcc8c 422 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 420 1.4E-169 T 29-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CDC59_RS06280 3ec76b62b1cc19970a813f5d7ebdcc8c 422 Gene3D G3DSA:3.40.50.20 2 84 2.5E-35 T 29-03-2018 CDC59_RS06280 3ec76b62b1cc19970a813f5d7ebdcc8c 422 SUPERFAMILY SSF56059 102 324 1.68E-65 T 29-03-2018 CDC59_RS06280 3ec76b62b1cc19970a813f5d7ebdcc8c 422 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 420 43.117 T 29-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CDC59_RS06280 3ec76b62b1cc19970a813f5d7ebdcc8c 422 Gene3D G3DSA:3.90.600.10 328 421 2.4E-33 T 29-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CDC59_RS06280 3ec76b62b1cc19970a813f5d7ebdcc8c 422 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 294 5.4E-77 T 29-03-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CDC59_RS06280 3ec76b62b1cc19970a813f5d7ebdcc8c 422 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 329 418 6.9E-30 T 29-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CDC59_RS06280 3ec76b62b1cc19970a813f5d7ebdcc8c 422 SMART SM01210 328 420 2.1E-51 T 29-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CDC59_RS11835 ceeef5d376bba0dbb68596afa360f524 315 Gene3D G3DSA:3.40.50.1000 5 244 1.3E-5 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS11835 ceeef5d376bba0dbb68596afa360f524 315 SUPERFAMILY SSF56784 8 252 2.89E-11 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS11650 1fdf2351a087a5611777d21ff0766483 212 Pfam PF05194 UreE urease accessory protein, C-terminal domain 78 192 1.2E-15 T 29-03-2018 IPR007864 Urease accessory protein UreE, C-terminal domain GO:0006461|GO:0016151|GO:0019627 CDC59_RS11650 1fdf2351a087a5611777d21ff0766483 212 Gene3D G3DSA:3.30.70.790 78 147 3.4E-26 T 29-03-2018 CDC59_RS11650 1fdf2351a087a5611777d21ff0766483 212 Hamap MF_00822 Urease accessory protein UreE [ureE]. 2 145 24.656 T 29-03-2018 IPR012406 Urease accessory protein UreE GO:0005737|GO:0006457|GO:0016151|GO:0018307 CDC59_RS11650 1fdf2351a087a5611777d21ff0766483 212 Gene3D G3DSA:2.60.260.20 1 77 2.9E-19 T 29-03-2018 CDC59_RS11650 1fdf2351a087a5611777d21ff0766483 212 SUPERFAMILY SSF69287 1 77 2.09E-16 T 29-03-2018 IPR004029 UreE urease accessory, N-terminal CDC59_RS11650 1fdf2351a087a5611777d21ff0766483 212 SMART SM00988 7 71 2.8E-18 T 29-03-2018 IPR004029 UreE urease accessory, N-terminal CDC59_RS11650 1fdf2351a087a5611777d21ff0766483 212 Pfam PF02814 UreE urease accessory protein, N-terminal domain 19 71 1.0E-17 T 29-03-2018 IPR004029 UreE urease accessory, N-terminal CDC59_RS11650 1fdf2351a087a5611777d21ff0766483 212 SUPERFAMILY SSF69737 77 144 3.4E-21 T 29-03-2018 IPR007864 Urease accessory protein UreE, C-terminal domain GO:0006461|GO:0016151|GO:0019627 CDC59_RS07925 4641eb4ac436ed05d8662cb7c5732f14 351 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 137 344 4.7E-36 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS07925 4641eb4ac436ed05d8662cb7c5732f14 351 Gene3D G3DSA:1.10.3720.10 2 334 2.7E-42 T 29-03-2018 CDC59_RS07925 4641eb4ac436ed05d8662cb7c5732f14 351 SUPERFAMILY SSF161098 113 328 4.97E-15 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS09930 6683a18fa7ae09807d8b4eddfe491956 295 Gene3D G3DSA:3.40.50.1820 6 293 1.1E-31 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS09930 6683a18fa7ae09807d8b4eddfe491956 295 PRINTS PR00412 Epoxide hydrolase signature 266 288 5.0E-5 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CDC59_RS09930 6683a18fa7ae09807d8b4eddfe491956 295 PRINTS PR00412 Epoxide hydrolase signature 130 143 5.0E-5 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CDC59_RS09930 6683a18fa7ae09807d8b4eddfe491956 295 PRINTS PR00412 Epoxide hydrolase signature 71 86 5.0E-5 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CDC59_RS09930 6683a18fa7ae09807d8b4eddfe491956 295 Pfam PF12697 Alpha/beta hydrolase family 61 283 2.2E-12 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS09930 6683a18fa7ae09807d8b4eddfe491956 295 SUPERFAMILY SSF53474 22 288 1.37E-39 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS21900 30ab4ce96db785a5b317df5380df45be 508 Gene3D G3DSA:1.20.1600.10 29 490 9.9E-109 T 29-03-2018 CDC59_RS21900 30ab4ce96db785a5b317df5380df45be 508 Pfam PF02321 Outer membrane efflux protein 299 483 2.0E-23 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CDC59_RS21900 30ab4ce96db785a5b317df5380df45be 508 Pfam PF02321 Outer membrane efflux protein 76 271 3.6E-27 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CDC59_RS21900 30ab4ce96db785a5b317df5380df45be 508 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 21 485 1.4E-167 T 29-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 CDC59_RS21900 30ab4ce96db785a5b317df5380df45be 508 SUPERFAMILY SSF56954 67 487 3.53E-111 T 29-03-2018 CDC59_RS21900 30ab4ce96db785a5b317df5380df45be 508 SUPERFAMILY SSF56954 9 43 3.53E-111 T 29-03-2018 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1768 1779 - T 29-03-2018 IPR020845 AMP-binding, conserved site CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Gene3D G3DSA:3.30.559.10 2231 2436 2.7E-21 T 29-03-2018 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Gene3D G3DSA:3.40.50.980 2858 3013 5.0E-35 T 29-03-2018 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Gene3D G3DSA:3.40.50.980 3911 4059 7.2E-26 T 29-03-2018 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Gene3D G3DSA:3.40.50.980 1774 1931 3.2E-39 T 29-03-2018 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Gene3D G3DSA:3.40.50.980 4960 5118 1.2E-29 T 29-03-2018 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 SMART SM00823 Phosphopantetheine attachment site 1078 1147 5.9E-4 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 SMART SM00823 Phosphopantetheine attachment site 4267 4336 0.0025 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 SMART SM00823 Phosphopantetheine attachment site 3215 3284 5.9E-4 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 SMART SM00823 Phosphopantetheine attachment site 5320 5388 0.0023 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1102 1117 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 SUPERFAMILY SSF53474 5387 5668 8.42E-50 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 SUPERFAMILY SSF56801 531 1091 7.06E-151 T 29-03-2018 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 ProSitePatterns PS00455 Putative AMP-binding domain signature. 4955 4966 - T 29-03-2018 IPR020845 AMP-binding, conserved site CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Gene3D G3DSA:3.40.50.1820 5393 5669 6.3E-16 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Gene3D G3DSA:3.40.50.1820 5691 5958 1.9E-19 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Gene3D G3DSA:3.30.559.10 3282 3501 9.2E-54 T 29-03-2018 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Gene3D G3DSA:3.30.559.10 4334 4553 1.2E-52 T 29-03-2018 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Gene3D G3DSA:3.30.559.10 1145 1364 2.0E-52 T 29-03-2018 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2728 3131 1.1E-140 T 29-03-2018 IPR010071 Amino acid adenylation domain CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 3786 4177 7.8E-132 T 29-03-2018 IPR010071 Amino acid adenylation domain CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1649 2050 5.0E-146 T 29-03-2018 IPR010071 Amino acid adenylation domain CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 588 988 1.6E-126 T 29-03-2018 IPR010071 Amino acid adenylation domain CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 4836 5236 2.1E-125 T 29-03-2018 IPR010071 Amino acid adenylation domain CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 SUPERFAMILY SSF52777 289 553 5.67E-47 T 29-03-2018 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Pfam PF00975 Thioesterase domain 5405 5509 1.8E-19 T 29-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Pfam PF00975 Thioesterase domain 5700 5825 2.0E-18 T 29-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Pfam PF00668 Condensation domain 108 499 8.3E-43 T 29-03-2018 IPR001242 Condensation domain CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Pfam PF00668 Condensation domain 3298 3745 1.1E-112 T 29-03-2018 IPR001242 Condensation domain CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Pfam PF00668 Condensation domain 2248 2685 1.3E-44 T 29-03-2018 IPR001242 Condensation domain CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Pfam PF00668 Condensation domain 4350 4794 2.7E-111 T 29-03-2018 IPR001242 Condensation domain CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Pfam PF00668 Condensation domain 1161 1608 3.6E-110 T 29-03-2018 IPR001242 Condensation domain CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Gene3D G3DSA:2.30.38.10 4062 4146 2.0E-26 T 29-03-2018 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 SUPERFAMILY SSF52777 1347 1615 3.45E-59 T 29-03-2018 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 SUPERFAMILY SSF52777 4354 4530 3.34E-55 T 29-03-2018 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 SUPERFAMILY SSF56801 3727 4280 4.58E-154 T 29-03-2018 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 SUPERFAMILY SSF52777 3485 3751 8.45E-60 T 29-03-2018 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 SUPERFAMILY SSF52777 2431 2693 8.89E-40 T 29-03-2018 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 SUPERFAMILY SSF47336 3207 3280 4.06E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Gene3D G3DSA:3.40.50.980 558 712 1.8E-41 T 29-03-2018 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Gene3D G3DSA:3.40.50.980 3756 3910 4.4E-49 T 29-03-2018 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Gene3D G3DSA:3.40.50.980 1619 1773 2.8E-49 T 29-03-2018 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Gene3D G3DSA:3.40.50.980 2698 2857 8.0E-49 T 29-03-2018 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 SUPERFAMILY SSF56801 1591 2147 1.15E-174 T 29-03-2018 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Gene3D G3DSA:2.30.38.10 872 953 2.3E-26 T 29-03-2018 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Gene3D G3DSA:2.30.38.10 1934 2015 1.5E-27 T 29-03-2018 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Gene3D G3DSA:2.30.38.10 5121 5202 8.6E-26 T 29-03-2018 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Gene3D G3DSA:1.10.1200.10 2138 2210 5.7E-19 T 29-03-2018 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Gene3D G3DSA:1.10.1200.10 5324 5392 1.6E-20 T 29-03-2018 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Gene3D G3DSA:1.10.1200.10 1082 1144 2.5E-23 T 29-03-2018 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Gene3D G3DSA:1.10.1200.10 4271 4333 2.5E-21 T 29-03-2018 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Gene3D G3DSA:1.10.1200.10 3219 3281 2.5E-23 T 29-03-2018 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 SUPERFAMILY SSF53474 5676 5954 4.79E-43 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 SUPERFAMILY SSF56801 2671 3228 3.01E-161 T 29-03-2018 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Gene3D G3DSA:3.40.50.980 713 863 1.2E-30 T 29-03-2018 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 SUPERFAMILY SSF47336 1070 1143 4.06E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 SUPERFAMILY SSF52777 1165 1341 4.78E-54 T 29-03-2018 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 ProSitePatterns PS00455 Putative AMP-binding domain signature. 3905 3916 - T 29-03-2018 IPR020845 AMP-binding, conserved site CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 SUPERFAMILY SSF52777 4537 4799 1.22E-60 T 29-03-2018 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 SUPERFAMILY SSF47336 4259 4332 1.83E-17 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Pfam PF00501 AMP-binding enzyme 4815 5212 1.9E-97 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Pfam PF00501 AMP-binding enzyme 567 964 2.0E-91 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Pfam PF00501 AMP-binding enzyme 1628 2026 8.8E-111 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Pfam PF00501 AMP-binding enzyme 3765 4153 1.4E-97 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Pfam PF00501 AMP-binding enzyme 2708 3107 2.6E-107 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Gene3D G3DSA:3.30.559.10 91 297 3.9E-24 T 29-03-2018 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4291 4306 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3239 3254 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 SUPERFAMILY SSF52777 3302 3478 1.56E-55 T 29-03-2018 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2852 2863 - T 29-03-2018 IPR020845 AMP-binding, conserved site CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Pfam PF00550 Phosphopantetheine attachment site 1080 1143 1.3E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Pfam PF00550 Phosphopantetheine attachment site 3217 3280 1.3E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Pfam PF00550 Phosphopantetheine attachment site 4270 4332 1.2E-10 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Pfam PF00550 Phosphopantetheine attachment site 2136 2196 4.3E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Pfam PF00550 Phosphopantetheine attachment site 5322 5384 6.4E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Gene3D G3DSA:3.40.50.980 4808 4959 3.9E-45 T 29-03-2018 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Gene3D G3DSA:2.30.38.10 3018 3100 5.9E-27 T 29-03-2018 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Gene3D G3DSA:3.30.300.30 4148 4270 3.1E-40 T 29-03-2018 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Gene3D G3DSA:3.30.300.30 2021 2137 6.7E-40 T 29-03-2018 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Gene3D G3DSA:3.30.300.30 959 1081 1.6E-40 T 29-03-2018 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Gene3D G3DSA:3.30.300.30 5207 5323 2.0E-36 T 29-03-2018 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Gene3D G3DSA:3.30.300.30 3102 3218 1.4E-39 T 29-03-2018 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 SUPERFAMILY SSF52777 2246 2442 1.45E-30 T 29-03-2018 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 ProSitePatterns PS00455 Putative AMP-binding domain signature. 708 719 - T 29-03-2018 IPR020845 AMP-binding, conserved site CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 SUPERFAMILY SSF47336 5312 5384 1.7E-17 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 SUPERFAMILY SSF52777 106 302 4.11E-32 T 29-03-2018 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 SUPERFAMILY SSF56801 4777 5333 1.96E-151 T 29-03-2018 CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 ProSitePatterns PS00012 Phosphopantetheine attachment site. 5344 5359 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 SUPERFAMILY SSF47336 2126 2196 2.09E-16 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Pfam PF13193 AMP-binding enzyme C-terminal domain 4161 4240 3.3E-11 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Pfam PF13193 AMP-binding enzyme C-terminal domain 5220 5293 8.4E-8 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Pfam PF13193 AMP-binding enzyme C-terminal domain 2034 2107 6.3E-11 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Pfam PF13193 AMP-binding enzyme C-terminal domain 972 1051 9.4E-10 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CDC59_RS19195 85e8213dfe89f7678f06dbc77901282d 5967 Pfam PF13193 AMP-binding enzyme C-terminal domain 3115 3188 2.3E-9 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CDC59_RS08215 5a89d1acb2019cf7dffac9f7cd8b4a3f 446 SMART SM00788 11 439 2.2E-292 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CDC59_RS08215 5a89d1acb2019cf7dffac9f7cd8b4a3f 446 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 18 25 - T 29-03-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CDC59_RS08215 5a89d1acb2019cf7dffac9f7cd8b4a3f 446 Pfam PF00709 Adenylosuccinate synthetase 12 438 1.5E-173 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CDC59_RS08215 5a89d1acb2019cf7dffac9f7cd8b4a3f 446 Gene3D G3DSA:3.90.170.10 274 446 5.2E-64 T 29-03-2018 CDC59_RS08215 5a89d1acb2019cf7dffac9f7cd8b4a3f 446 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 446 209.721 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CDC59_RS08215 5a89d1acb2019cf7dffac9f7cd8b4a3f 446 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 140 151 - T 29-03-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CDC59_RS08215 5a89d1acb2019cf7dffac9f7cd8b4a3f 446 SUPERFAMILY SSF52540 11 444 1.27E-170 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS08215 5a89d1acb2019cf7dffac9f7cd8b4a3f 446 Gene3D G3DSA:3.40.440.10 8 158 3.7E-54 T 29-03-2018 CDC59_RS08215 5a89d1acb2019cf7dffac9f7cd8b4a3f 446 Gene3D G3DSA:3.40.440.10 159 273 1.8E-25 T 29-03-2018 CDC59_RS08215 5a89d1acb2019cf7dffac9f7cd8b4a3f 446 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 13 444 6.3E-170 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CDC59_RS15590 613ef638142552c7c0027492c09b5348 1672 Gene3D G3DSA:2.60.500.10 1079 1169 2.5E-6 T 29-03-2018 CDC59_RS15590 613ef638142552c7c0027492c09b5348 1672 Gene3D G3DSA:2.60.500.10 262 346 1.9E-12 T 29-03-2018 CDC59_RS15590 613ef638142552c7c0027492c09b5348 1672 Gene3D G3DSA:2.60.500.10 61 174 0.0015 T 29-03-2018 CDC59_RS15590 613ef638142552c7c0027492c09b5348 1672 Gene3D G3DSA:2.60.500.10 1170 1278 1.0E-9 T 29-03-2018 CDC59_RS15590 613ef638142552c7c0027492c09b5348 1672 SMART SM00429 172 256 5.7E-6 T 29-03-2018 IPR002909 IPT domain CDC59_RS15590 613ef638142552c7c0027492c09b5348 1672 Gene3D G3DSA:2.60.40.10 175 261 1.9E-19 T 29-03-2018 IPR013783 Immunoglobulin-like fold CDC59_RS15590 613ef638142552c7c0027492c09b5348 1672 SUPERFAMILY SSF49313 809 897 1.96E-11 T 29-03-2018 IPR015919 Cadherin-like GO:0005509|GO:0016020 CDC59_RS15590 613ef638142552c7c0027492c09b5348 1672 SUPERFAMILY SSF49313 721 784 5.18E-7 T 29-03-2018 IPR015919 Cadherin-like GO:0005509|GO:0016020 CDC59_RS15590 613ef638142552c7c0027492c09b5348 1672 SUPERFAMILY SSF103515 1393 1669 7.06E-45 T 29-03-2018 IPR005546 Autotransporter beta-domain CDC59_RS15590 613ef638142552c7c0027492c09b5348 1672 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 1381 1657 6.2E-19 T 29-03-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 CDC59_RS15590 613ef638142552c7c0027492c09b5348 1672 SMART SM00736 533 627 0.052 T 29-03-2018 IPR006644 Dystroglycan-type cadherin-like GO:0016020 CDC59_RS15590 613ef638142552c7c0027492c09b5348 1672 SMART SM00736 439 532 0.1 T 29-03-2018 IPR006644 Dystroglycan-type cadherin-like GO:0016020 CDC59_RS15590 613ef638142552c7c0027492c09b5348 1672 SMART SM00736 807 902 0.0047 T 29-03-2018 IPR006644 Dystroglycan-type cadherin-like GO:0016020 CDC59_RS15590 613ef638142552c7c0027492c09b5348 1672 SUPERFAMILY SSF81296 173 256 3.69E-16 T 29-03-2018 IPR014756 Immunoglobulin E-set CDC59_RS15590 613ef638142552c7c0027492c09b5348 1672 SUPERFAMILY SSF49313 629 710 6.28E-10 T 29-03-2018 IPR015919 Cadherin-like GO:0005509|GO:0016020 CDC59_RS15590 613ef638142552c7c0027492c09b5348 1672 Gene3D G3DSA:2.60.40.10 432 522 2.0E-8 T 29-03-2018 IPR013783 Immunoglobulin-like fold CDC59_RS15590 613ef638142552c7c0027492c09b5348 1672 Gene3D G3DSA:2.60.40.10 617 709 6.7E-12 T 29-03-2018 IPR013783 Immunoglobulin-like fold CDC59_RS15590 613ef638142552c7c0027492c09b5348 1672 Gene3D G3DSA:2.60.40.10 894 984 1.6E-7 T 29-03-2018 IPR013783 Immunoglobulin-like fold CDC59_RS15590 613ef638142552c7c0027492c09b5348 1672 Gene3D G3DSA:2.60.40.10 523 616 2.0E-6 T 29-03-2018 IPR013783 Immunoglobulin-like fold CDC59_RS15590 613ef638142552c7c0027492c09b5348 1672 Gene3D G3DSA:2.60.40.10 798 893 3.0E-9 T 29-03-2018 IPR013783 Immunoglobulin-like fold CDC59_RS15590 613ef638142552c7c0027492c09b5348 1672 Gene3D G3DSA:2.60.40.10 347 431 1.2E-6 T 29-03-2018 IPR013783 Immunoglobulin-like fold CDC59_RS15590 613ef638142552c7c0027492c09b5348 1672 Gene3D G3DSA:2.60.40.10 985 1077 2.3E-8 T 29-03-2018 IPR013783 Immunoglobulin-like fold CDC59_RS15590 613ef638142552c7c0027492c09b5348 1672 Gene3D G3DSA:2.60.40.10 710 797 5.3E-7 T 29-03-2018 IPR013783 Immunoglobulin-like fold CDC59_RS15590 613ef638142552c7c0027492c09b5348 1672 SMART SM00869 1398 1662 4.9E-42 T 29-03-2018 IPR005546 Autotransporter beta-domain CDC59_RS15590 613ef638142552c7c0027492c09b5348 1672 Pfam PF05345 Putative Ig domain 930 970 4.3E-8 T 29-03-2018 IPR008009 Putative Ig CDC59_RS15590 613ef638142552c7c0027492c09b5348 1672 Pfam PF05345 Putative Ig domain 1017 1059 1.6E-7 T 29-03-2018 IPR008009 Putative Ig CDC59_RS15590 613ef638142552c7c0027492c09b5348 1672 Pfam PF05345 Putative Ig domain 656 696 9.8E-11 T 29-03-2018 IPR008009 Putative Ig CDC59_RS15590 613ef638142552c7c0027492c09b5348 1672 Pfam PF05345 Putative Ig domain 836 879 8.1E-9 T 29-03-2018 IPR008009 Putative Ig CDC59_RS15590 613ef638142552c7c0027492c09b5348 1672 Pfam PF05345 Putative Ig domain 469 510 3.6E-6 T 29-03-2018 IPR008009 Putative Ig CDC59_RS15590 613ef638142552c7c0027492c09b5348 1672 Pfam PF05345 Putative Ig domain 743 783 9.4E-8 T 29-03-2018 IPR008009 Putative Ig CDC59_RS15590 613ef638142552c7c0027492c09b5348 1672 Pfam PF05345 Putative Ig domain 561 604 6.9E-9 T 29-03-2018 IPR008009 Putative Ig CDC59_RS15590 613ef638142552c7c0027492c09b5348 1672 Pfam PF05345 Putative Ig domain 377 418 5.6E-8 T 29-03-2018 IPR008009 Putative Ig CDC59_RS15590 613ef638142552c7c0027492c09b5348 1672 SUPERFAMILY SSF49313 538 619 4.39E-9 T 29-03-2018 IPR015919 Cadherin-like GO:0005509|GO:0016020 CDC59_RS15590 613ef638142552c7c0027492c09b5348 1672 Pfam PF03797 Autotransporter beta-domain 1401 1651 6.5E-49 T 29-03-2018 IPR005546 Autotransporter beta-domain CDC59_RS15590 613ef638142552c7c0027492c09b5348 1672 SUPERFAMILY SSF49313 442 526 4.08E-6 T 29-03-2018 IPR015919 Cadherin-like GO:0005509|GO:0016020 CDC59_RS15590 613ef638142552c7c0027492c09b5348 1672 SUPERFAMILY SSF49313 910 983 2.98E-7 T 29-03-2018 IPR015919 Cadherin-like GO:0005509|GO:0016020 CDC59_RS15590 613ef638142552c7c0027492c09b5348 1672 SUPERFAMILY SSF49313 988 1076 5.18E-8 T 29-03-2018 IPR015919 Cadherin-like GO:0005509|GO:0016020 CDC59_RS15590 613ef638142552c7c0027492c09b5348 1672 SUPERFAMILY SSF49313 355 436 8.63E-8 T 29-03-2018 IPR015919 Cadherin-like GO:0005509|GO:0016020 CDC59_RS15590 613ef638142552c7c0027492c09b5348 1672 Gene3D G3DSA:2.40.128.130 1279 1672 1.0E-49 T 29-03-2018 CDC59_RS15590 613ef638142552c7c0027492c09b5348 1672 Pfam PF01833 IPT/TIG domain 173 255 2.1E-12 T 29-03-2018 IPR002909 IPT domain CDC59_RS18975 9b43b8379427d975b5fb418707154217 363 Gene3D G3DSA:2.40.30.10 1 110 1.9E-20 T 29-03-2018 CDC59_RS18975 9b43b8379427d975b5fb418707154217 363 SUPERFAMILY SSF52343 102 250 3.14E-36 T 29-03-2018 CDC59_RS18975 9b43b8379427d975b5fb418707154217 363 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 86 95 2.1E-6 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CDC59_RS18975 9b43b8379427d975b5fb418707154217 363 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 220 228 2.1E-6 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CDC59_RS18975 9b43b8379427d975b5fb418707154217 363 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 149 158 2.1E-6 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CDC59_RS18975 9b43b8379427d975b5fb418707154217 363 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 59 66 2.1E-6 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CDC59_RS18975 9b43b8379427d975b5fb418707154217 363 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 124 143 2.1E-6 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CDC59_RS18975 9b43b8379427d975b5fb418707154217 363 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 279 351 8.5E-13 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CDC59_RS18975 9b43b8379427d975b5fb418707154217 363 Pfam PF00970 Oxidoreductase FAD-binding domain 8 112 1.1E-11 T 29-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CDC59_RS18975 9b43b8379427d975b5fb418707154217 363 Gene3D G3DSA:3.40.50.80 113 249 2.2E-30 T 29-03-2018 CDC59_RS18975 9b43b8379427d975b5fb418707154217 363 SUPERFAMILY SSF63380 2 112 1.62E-23 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CDC59_RS18975 9b43b8379427d975b5fb418707154217 363 SUPERFAMILY SSF54292 242 360 5.12E-27 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CDC59_RS18975 9b43b8379427d975b5fb418707154217 363 PRINTS PR00406 Cytochrome B5 reductase signature 161 172 9.8E-7 T 29-03-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 CDC59_RS18975 9b43b8379427d975b5fb418707154217 363 PRINTS PR00406 Cytochrome B5 reductase signature 99 113 9.8E-7 T 29-03-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 CDC59_RS18975 9b43b8379427d975b5fb418707154217 363 PRINTS PR00406 Cytochrome B5 reductase signature 220 228 9.8E-7 T 29-03-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 CDC59_RS18975 9b43b8379427d975b5fb418707154217 363 PRINTS PR00406 Cytochrome B5 reductase signature 124 143 9.8E-7 T 29-03-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 CDC59_RS18975 9b43b8379427d975b5fb418707154217 363 Pfam PF00175 Oxidoreductase NAD-binding domain 127 234 5.0E-17 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CDC59_RS18975 9b43b8379427d975b5fb418707154217 363 Gene3D G3DSA:3.10.20.30 250 363 1.9E-28 T 29-03-2018 IPR012675 Beta-grasp domain CDC59_RS18975 9b43b8379427d975b5fb418707154217 363 TIGRFAM TIGR02160 PA_CoA_Oxy5: phenylacetate-CoA oxygenase/reductase, PaaK subunit 5 361 1.6E-136 T 29-03-2018 IPR011884 Phenylacetate-CoA oxygenase/reductase, PaaK subunit GO:0010124 CDC59_RS05450 959118c9db0fe9781c0c7443587ba623 885 SMART SM00434 11 506 9.8E-291 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDC59_RS05450 959118c9db0fe9781c0c7443587ba623 885 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 32 513 5.2E-156 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDC59_RS05450 959118c9db0fe9781c0c7443587ba623 885 Gene3D G3DSA:2.120.10.90 540 874 1.1E-129 T 29-03-2018 CDC59_RS05450 959118c9db0fe9781c0c7443587ba623 885 SUPERFAMILY SSF56719 30 528 1.23E-181 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CDC59_RS05450 959118c9db0fe9781c0c7443587ba623 885 SUPERFAMILY SSF101904 540 865 3.27E-108 T 29-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal CDC59_RS05450 959118c9db0fe9781c0c7443587ba623 885 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 7 858 24.377 T 29-03-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CDC59_RS05450 959118c9db0fe9781c0c7443587ba623 885 Gene3D G3DSA:3.30.1360.40 236 333 2.9E-37 T 29-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CDC59_RS05450 959118c9db0fe9781c0c7443587ba623 885 Gene3D G3DSA:1.10.268.10 345 528 9.2E-53 T 29-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDC59_RS05450 959118c9db0fe9781c0c7443587ba623 885 Gene3D G3DSA:3.90.199.10 34 214 2.9E-88 T 29-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 CDC59_RS05450 959118c9db0fe9781c0c7443587ba623 885 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 760 806 1.1E-13 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CDC59_RS05450 959118c9db0fe9781c0c7443587ba623 885 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 653 695 4.9E-9 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CDC59_RS05450 959118c9db0fe9781c0c7443587ba623 885 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 545 592 2.8E-10 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CDC59_RS05450 959118c9db0fe9781c0c7443587ba623 885 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 700 745 8.6E-15 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CDC59_RS05450 959118c9db0fe9781c0c7443587ba623 885 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 810 855 4.4E-11 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CDC59_RS05450 959118c9db0fe9781c0c7443587ba623 885 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 595 642 1.3E-8 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CDC59_RS05450 959118c9db0fe9781c0c7443587ba623 885 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 10 857 0.0 T 29-03-2018 CDC59_RS02215 75389e2aab01f1771342dbc2c2347e06 156 PIRSF PIRSF002122 3 156 1.0E-58 T 29-03-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 CDC59_RS02215 75389e2aab01f1771342dbc2c2347e06 156 SUPERFAMILY SSF47973 2 149 5.1E-61 T 29-03-2018 IPR023798 Ribosomal protein S7 domain CDC59_RS02215 75389e2aab01f1771342dbc2c2347e06 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 35.086 T 29-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 CDC59_RS02215 75389e2aab01f1771342dbc2c2347e06 156 Gene3D G3DSA:1.10.455.10 6 156 1.6E-59 T 29-03-2018 IPR023798 Ribosomal protein S7 domain CDC59_RS02215 75389e2aab01f1771342dbc2c2347e06 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 29-03-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS02215 75389e2aab01f1771342dbc2c2347e06 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 155 2.9E-64 T 29-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 CDC59_RS02215 75389e2aab01f1771342dbc2c2347e06 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 6.5E-66 T 29-03-2018 IPR023798 Ribosomal protein S7 domain CDC59_RS13760 2b80a2e39568df25de689b8ab2d8a6e7 166 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 4 148 5.3E-50 T 29-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 CDC59_RS13760 2b80a2e39568df25de689b8ab2d8a6e7 166 SUPERFAMILY SSF69500 4 149 6.67E-51 T 29-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain CDC59_RS13760 2b80a2e39568df25de689b8ab2d8a6e7 166 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 150 32.882 T 29-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 CDC59_RS13760 2b80a2e39568df25de689b8ab2d8a6e7 166 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 2 150 8.1E-55 T 29-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 CDC59_RS13760 2b80a2e39568df25de689b8ab2d8a6e7 166 Gene3D G3DSA:3.50.80.10 2 150 1.3E-49 T 29-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain CDC59_RS06640 7ed88adcec5fbe31717fc236727a2026 788 TIGRFAM TIGR02965 xanthine_xdhB: xanthine dehydrogenase, molybdopterin binding subunit 27 782 0.0 T 29-03-2018 IPR014309 Xanthine dehydrogenase, molybdopterin binding subunit GO:0030151 KEGG: 00230+1.17.1.4+1.17.3.2|KEGG: 00232+1.17.3.2|KEGG: 00983+1.17.3.2|MetaCyc: PWY-5497|MetaCyc: PWY-5695|MetaCyc: PWY-6538|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-6999 CDC59_RS06640 7ed88adcec5fbe31717fc236727a2026 788 Gene3D G3DSA:3.90.1170.50 25 148 2.0E-33 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CDC59_RS06640 7ed88adcec5fbe31717fc236727a2026 788 SMART SM01008 41 148 3.2E-50 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CDC59_RS06640 7ed88adcec5fbe31717fc236727a2026 788 SUPERFAMILY SSF56003 148 780 5.36E-207 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CDC59_RS06640 7ed88adcec5fbe31717fc236727a2026 788 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 169 711 7.7E-200 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CDC59_RS06640 7ed88adcec5fbe31717fc236727a2026 788 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 42 148 3.4E-28 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CDC59_RS06640 7ed88adcec5fbe31717fc236727a2026 788 Gene3D G3DSA:3.30.365.10 170 278 1.4E-29 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CDC59_RS06640 7ed88adcec5fbe31717fc236727a2026 788 Gene3D G3DSA:3.30.365.10 461 621 7.3E-50 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CDC59_RS06640 7ed88adcec5fbe31717fc236727a2026 788 SUPERFAMILY SSF54665 25 149 3.79E-41 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CDC59_RS06640 7ed88adcec5fbe31717fc236727a2026 788 Gene3D G3DSA:3.30.365.10 279 441 6.7E-58 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CDC59_RS06640 7ed88adcec5fbe31717fc236727a2026 788 Gene3D G3DSA:3.30.365.10 622 783 3.2E-62 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CDC59_RS18285 a287f86c7f5b36ac065d8462e4662e11 338 ProSitePatterns PS01276 Peptidase family U32 signature. 168 186 - T 29-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 CDC59_RS18285 a287f86c7f5b36ac065d8462e4662e11 338 Pfam PF01136 Peptidase family U32 83 337 3.7E-65 T 29-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 CDC59_RS18285 a287f86c7f5b36ac065d8462e4662e11 338 Gene3D G3DSA:3.20.20.150 8 337 1.7E-17 T 29-03-2018 CDC59_RS07040 40f6e2d1a6fac44ba80aca95edefb0ca 202 Pfam PF13302 Acetyltransferase (GNAT) domain 16 157 4.8E-12 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CDC59_RS07040 40f6e2d1a6fac44ba80aca95edefb0ca 202 Gene3D G3DSA:3.40.630.30 2 199 4.4E-24 T 29-03-2018 CDC59_RS07040 40f6e2d1a6fac44ba80aca95edefb0ca 202 SUPERFAMILY SSF55729 6 182 4.51E-33 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDC59_RS14465 3a47f55906597e69ce2351d59d5a726d 523 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 43 265 6.2E-58 T 29-03-2018 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS14465 3a47f55906597e69ce2351d59d5a726d 523 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 35 115 6.6E-14 T 29-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS14465 3a47f55906597e69ce2351d59d5a726d 523 SUPERFAMILY SSF103088 420 500 1.22E-20 T 29-03-2018 IPR006665 OmpA-like domain CDC59_RS14465 3a47f55906597e69ce2351d59d5a726d 523 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 130 254 1.0E-37 T 29-03-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS14465 3a47f55906597e69ce2351d59d5a726d 523 SUPERFAMILY SSF81464 31 124 1.1E-26 T 29-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS14465 3a47f55906597e69ce2351d59d5a726d 523 Gene3D G3DSA:1.10.760.10 266 391 3.1E-19 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS14465 3a47f55906597e69ce2351d59d5a726d 523 SUPERFAMILY SSF49503 127 270 3.85E-51 T 29-03-2018 IPR008972 Cupredoxin CDC59_RS14465 3a47f55906597e69ce2351d59d5a726d 523 PRINTS PR01166 Cytochrome c oxidase subunit II signature 104 124 6.8E-39 T 29-03-2018 CDC59_RS14465 3a47f55906597e69ce2351d59d5a726d 523 PRINTS PR01166 Cytochrome c oxidase subunit II signature 220 237 6.8E-39 T 29-03-2018 CDC59_RS14465 3a47f55906597e69ce2351d59d5a726d 523 PRINTS PR01166 Cytochrome c oxidase subunit II signature 92 104 6.8E-39 T 29-03-2018 CDC59_RS14465 3a47f55906597e69ce2351d59d5a726d 523 PRINTS PR01166 Cytochrome c oxidase subunit II signature 238 255 6.8E-39 T 29-03-2018 CDC59_RS14465 3a47f55906597e69ce2351d59d5a726d 523 PRINTS PR01166 Cytochrome c oxidase subunit II signature 126 145 6.8E-39 T 29-03-2018 CDC59_RS14465 3a47f55906597e69ce2351d59d5a726d 523 PRINTS PR01166 Cytochrome c oxidase subunit II signature 176 197 6.8E-39 T 29-03-2018 CDC59_RS14465 3a47f55906597e69ce2351d59d5a726d 523 PRINTS PR01166 Cytochrome c oxidase subunit II signature 200 220 6.8E-39 T 29-03-2018 CDC59_RS14465 3a47f55906597e69ce2351d59d5a726d 523 Gene3D G3DSA:3.30.1330.60 395 519 1.3E-22 T 29-03-2018 IPR006665 OmpA-like domain CDC59_RS14465 3a47f55906597e69ce2351d59d5a726d 523 SUPERFAMILY SSF46626 235 370 1.13E-23 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS14465 3a47f55906597e69ce2351d59d5a726d 523 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 201 249 - T 29-03-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS14465 3a47f55906597e69ce2351d59d5a726d 523 Pfam PF00691 OmpA family 426 499 6.0E-15 T 29-03-2018 IPR006665 OmpA-like domain CDC59_RS14465 3a47f55906597e69ce2351d59d5a726d 523 PRINTS PR01021 OMPA domain signature 457 472 1.6E-8 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CDC59_RS14465 3a47f55906597e69ce2351d59d5a726d 523 PRINTS PR01021 OMPA domain signature 427 449 1.6E-8 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CDC59_RS14465 3a47f55906597e69ce2351d59d5a726d 523 PRINTS PR01021 OMPA domain signature 472 488 1.6E-8 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CDC59_RS14465 3a47f55906597e69ce2351d59d5a726d 523 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 290 359 2.5E-13 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS14465 3a47f55906597e69ce2351d59d5a726d 523 Gene3D G3DSA:2.60.40.420 127 265 1.2E-45 T 29-03-2018 IPR008972 Cupredoxin CDC59_RS14465 3a47f55906597e69ce2351d59d5a726d 523 Gene3D G3DSA:1.10.287.90 32 125 5.3E-27 T 29-03-2018 CDC59_RS09815 dd54b7598e9b684ff0217cdadd110b87 205 Gene3D G3DSA:3.40.50.300 1 205 3.5E-50 T 29-03-2018 CDC59_RS09815 dd54b7598e9b684ff0217cdadd110b87 205 Pfam PF02223 Thymidylate kinase 8 196 3.2E-46 T 29-03-2018 CDC59_RS09815 dd54b7598e9b684ff0217cdadd110b87 205 Hamap MF_00165 Thymidylate kinase [tmk]. 4 205 28.377 T 29-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CDC59_RS09815 dd54b7598e9b684ff0217cdadd110b87 205 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 2 196 3.3E-50 T 29-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CDC59_RS09815 dd54b7598e9b684ff0217cdadd110b87 205 SUPERFAMILY SSF52540 1 201 2.04E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS12165 e9f561cef43f4fd1fe4d5269f58d609b 294 Gene3D G3DSA:3.40.190.10 83 184 2.0E-21 T 29-03-2018 CDC59_RS12165 e9f561cef43f4fd1fe4d5269f58d609b 294 Pfam PF03466 LysR substrate binding domain 87 285 2.6E-34 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS12165 e9f561cef43f4fd1fe4d5269f58d609b 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 2.5E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS12165 e9f561cef43f4fd1fe4d5269f58d609b 294 Gene3D G3DSA:1.10.10.10 1 82 7.2E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS12165 e9f561cef43f4fd1fe4d5269f58d609b 294 Gene3D G3DSA:3.40.190.10 185 261 6.9E-5 T 29-03-2018 CDC59_RS12165 e9f561cef43f4fd1fe4d5269f58d609b 294 SUPERFAMILY SSF53850 87 286 8.32E-38 T 29-03-2018 CDC59_RS12165 e9f561cef43f4fd1fe4d5269f58d609b 294 SUPERFAMILY SSF46785 1 87 2.51E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS02705 951b2636abd7adce89be7a2ba302a4ff 203 Gene3D G3DSA:1.20.1050.10 88 203 3.5E-22 T 29-03-2018 CDC59_RS02705 951b2636abd7adce89be7a2ba302a4ff 203 Gene3D G3DSA:3.40.30.10 1 87 2.5E-28 T 29-03-2018 CDC59_RS02705 951b2636abd7adce89be7a2ba302a4ff 203 Pfam PF00043 Glutathione S-transferase, C-terminal domain 114 188 1.1E-7 T 29-03-2018 IPR004046 Glutathione S-transferase, C-terminal CDC59_RS02705 951b2636abd7adce89be7a2ba302a4ff 203 SUPERFAMILY SSF52833 1 101 9.42E-28 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS02705 951b2636abd7adce89be7a2ba302a4ff 203 SUPERFAMILY SSF47616 73 202 9.1E-24 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like CDC59_RS02705 951b2636abd7adce89be7a2ba302a4ff 203 Pfam PF13417 Glutathione S-transferase, N-terminal domain 4 77 1.0E-17 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CDC59_RS08490 d26c26e9979705ef1a031594908110ff 846 SUPERFAMILY SSF56784 592 839 9.82E-43 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS08490 d26c26e9979705ef1a031594908110ff 846 SUPERFAMILY SSF56784 535 554 9.82E-43 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS08490 d26c26e9979705ef1a031594908110ff 846 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 275 842 7.6E-146 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CDC59_RS08490 d26c26e9979705ef1a031594908110ff 846 SUPERFAMILY SSF81665 445 530 1.31E-12 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CDC59_RS08490 d26c26e9979705ef1a031594908110ff 846 SUPERFAMILY SSF81665 789 819 1.31E-12 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CDC59_RS08490 d26c26e9979705ef1a031594908110ff 846 Gene3D G3DSA:1.20.1110.10 276 552 3.8E-33 T 29-03-2018 CDC59_RS08490 d26c26e9979705ef1a031594908110ff 846 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 310 557 8.0E-32 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CDC59_RS08490 d26c26e9979705ef1a031594908110ff 846 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 652 817 1.5E-32 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CDC59_RS08490 d26c26e9979705ef1a031594908110ff 846 SUPERFAMILY SSF55008 118 189 1.96E-18 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CDC59_RS08490 d26c26e9979705ef1a031594908110ff 846 Gene3D G3DSA:3.40.1110.10 553 669 6.8E-17 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CDC59_RS08490 d26c26e9979705ef1a031594908110ff 846 SUPERFAMILY SSF81653 342 437 5.62E-21 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CDC59_RS08490 d26c26e9979705ef1a031594908110ff 846 Gene3D G3DSA:3.40.50.1000 670 812 3.4E-33 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS08490 d26c26e9979705ef1a031594908110ff 846 ProSitePatterns PS01047 Heavy-metal-associated domain. 127 156 - T 29-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CDC59_RS08490 d26c26e9979705ef1a031594908110ff 846 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 538 544 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CDC59_RS08490 d26c26e9979705ef1a031594908110ff 846 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 536 550 7.2E-19 T 29-03-2018 CDC59_RS08490 d26c26e9979705ef1a031594908110ff 846 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 687 697 7.2E-19 T 29-03-2018 CDC59_RS08490 d26c26e9979705ef1a031594908110ff 846 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 763 775 7.2E-19 T 29-03-2018 CDC59_RS08490 d26c26e9979705ef1a031594908110ff 846 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 740 759 7.2E-19 T 29-03-2018 CDC59_RS08490 d26c26e9979705ef1a031594908110ff 846 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 388 402 7.2E-19 T 29-03-2018 CDC59_RS08490 d26c26e9979705ef1a031594908110ff 846 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 257 842 4.0E-134 T 29-03-2018 CDC59_RS08490 d26c26e9979705ef1a031594908110ff 846 Pfam PF00403 Heavy-metal-associated domain 127 185 1.7E-10 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CDC59_RS08490 d26c26e9979705ef1a031594908110ff 846 Pfam PF00122 E1-E2 ATPase 337 516 4.3E-42 T 29-03-2018 CDC59_RS08490 d26c26e9979705ef1a031594908110ff 846 Gene3D G3DSA:3.30.70.100 119 188 2.4E-17 T 29-03-2018 CDC59_RS08490 d26c26e9979705ef1a031594908110ff 846 Pfam PF12156 Putative metal-binding domain of cation transport ATPase 32 116 1.3E-18 T 29-03-2018 IPR021993 Putative metal-binding domain of cation transport ATPase CDC59_RS08490 d26c26e9979705ef1a031594908110ff 846 Pfam PF00702 haloacid dehalogenase-like hydrolase 535 753 4.9E-30 T 29-03-2018 CDC59_RS11720 9728497a364df74651a0a0c2514221e4 379 Gene3D G3DSA:2.40.110.10 125 217 4.0E-17 T 29-03-2018 CDC59_RS11720 9728497a364df74651a0a0c2514221e4 379 Gene3D G3DSA:1.20.140.10 234 358 3.1E-31 T 29-03-2018 CDC59_RS11720 9728497a364df74651a0a0c2514221e4 379 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 354 2.1E-23 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CDC59_RS11720 9728497a364df74651a0a0c2514221e4 379 SUPERFAMILY SSF47203 225 370 1.13E-34 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CDC59_RS11720 9728497a364df74651a0a0c2514221e4 379 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 118 213 4.9E-14 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CDC59_RS11720 9728497a364df74651a0a0c2514221e4 379 Gene3D G3DSA:1.10.540.10 1 124 6.0E-18 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CDC59_RS11720 9728497a364df74651a0a0c2514221e4 379 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 94 6.5E-12 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CDC59_RS11720 9728497a364df74651a0a0c2514221e4 379 SUPERFAMILY SSF56645 1 216 3.8E-41 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CDC59_RS22260 75cb4c750f5e53056714c23070420c86 140 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 18 136 9.6E-32 T 29-03-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 CDC59_RS22260 75cb4c750f5e53056714c23070420c86 140 Pfam PF02675 S-adenosylmethionine decarboxylase 21 136 7.0E-37 T 29-03-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 CDC59_RS22260 75cb4c750f5e53056714c23070420c86 140 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 15 140 24.165 T 29-03-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 CDC59_RS22260 75cb4c750f5e53056714c23070420c86 140 Gene3D G3DSA:3.60.90.10 8 138 5.7E-37 T 29-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 CDC59_RS22260 75cb4c750f5e53056714c23070420c86 140 SUPERFAMILY SSF56276 18 136 3.92E-31 T 29-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 CDC59_RS11390 bba47e95a5f6977cee4544263893ebbd 279 Gene3D G3DSA:3.30.70.1070 199 279 5.8E-11 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 CDC59_RS11390 bba47e95a5f6977cee4544263893ebbd 279 SUPERFAMILY SSF110997 203 276 1.44E-9 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 CDC59_RS11390 bba47e95a5f6977cee4544263893ebbd 279 Pfam PF05036 Sporulation related domain 204 272 1.3E-10 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 CDC59_RS09595 b12e2a9602c576f06306d16e0e6f6b42 416 Hamap MF_01693 8-amino-7-oxononanoate synthase [bioF]. 3 406 49.423 T 29-03-2018 IPR022834 8-amino-7-oxononanoate synthase, Proteobacteria GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 CDC59_RS09595 b12e2a9602c576f06306d16e0e6f6b42 416 TIGRFAM TIGR00858 bioF: 8-amino-7-oxononanoate synthase 20 403 1.7E-145 T 29-03-2018 IPR004723 8-amino-7-oxononanoate synthase, Archaea/Proteobacteria type GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 CDC59_RS09595 b12e2a9602c576f06306d16e0e6f6b42 416 Gene3D G3DSA:3.90.1150.10 299 414 6.2E-27 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS09595 b12e2a9602c576f06306d16e0e6f6b42 416 SUPERFAMILY SSF53383 31 407 5.92E-97 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS09595 b12e2a9602c576f06306d16e0e6f6b42 416 Gene3D G3DSA:3.40.640.10 124 298 1.4E-51 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDC59_RS09595 b12e2a9602c576f06306d16e0e6f6b42 416 Gene3D G3DSA:3.90.1150.10 9 106 1.2E-5 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS09595 b12e2a9602c576f06306d16e0e6f6b42 416 Pfam PF00155 Aminotransferase class I and II 45 402 5.1E-53 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CDC59_RS17215 67ee323864ab68eb0d5c72620a32dbe5 549 Pfam PF13428 Tetratricopeptide repeat 37 78 4.1E-5 T 29-03-2018 CDC59_RS17215 67ee323864ab68eb0d5c72620a32dbe5 549 Gene3D G3DSA:3.40.50.2000 354 546 1.6E-21 T 29-03-2018 CDC59_RS17215 67ee323864ab68eb0d5c72620a32dbe5 549 SUPERFAMILY SSF48452 38 239 1.76E-15 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS17215 67ee323864ab68eb0d5c72620a32dbe5 549 Gene3D G3DSA:1.25.40.10 138 245 2.5E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS17215 67ee323864ab68eb0d5c72620a32dbe5 549 Gene3D G3DSA:1.25.40.10 13 98 2.6E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS17215 67ee323864ab68eb0d5c72620a32dbe5 549 SUPERFAMILY SSF53756 260 390 2.1E-9 T 29-03-2018 CDC59_RS17215 67ee323864ab68eb0d5c72620a32dbe5 549 Gene3D G3DSA:1.25.40.10 99 137 6.7E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS17215 67ee323864ab68eb0d5c72620a32dbe5 549 SUPERFAMILY SSF53756 447 532 4.39E-7 T 29-03-2018 CDC59_RS15335 34b9d3ad03f99cbc92fff1c2ae1b343f 381 Gene3D G3DSA:3.40.1710.10 46 201 4.8E-28 T 29-03-2018 CDC59_RS15335 34b9d3ad03f99cbc92fff1c2ae1b343f 381 Pfam PF12698 ABC-2 family transporter protein 30 373 1.9E-48 T 29-03-2018 CDC59_RS12185 6859a3f581ababb8ed6002dd3815ad47 471 Pfam PF00206 Lyase 15 308 2.0E-76 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal CDC59_RS12185 6859a3f581ababb8ed6002dd3815ad47 471 ProSitePatterns PS00163 Fumarate lyases signature. 283 292 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CDC59_RS12185 6859a3f581ababb8ed6002dd3815ad47 471 Gene3D G3DSA:1.10.40.30 383 446 2.4E-25 T 29-03-2018 CDC59_RS12185 6859a3f581ababb8ed6002dd3815ad47 471 Gene3D G3DSA:1.20.200.10 115 382 2.9E-98 T 29-03-2018 CDC59_RS12185 6859a3f581ababb8ed6002dd3815ad47 471 Hamap MF_00006 Argininosuccinate lyase [argH]. 10 467 43.25 T 29-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CDC59_RS12185 6859a3f581ababb8ed6002dd3815ad47 471 Gene3D G3DSA:1.10.275.10 10 114 2.4E-35 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal CDC59_RS12185 6859a3f581ababb8ed6002dd3815ad47 471 TIGRFAM TIGR00838 argH: argininosuccinate lyase 12 468 4.6E-183 T 29-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CDC59_RS12185 6859a3f581ababb8ed6002dd3815ad47 471 SUPERFAMILY SSF48557 12 467 1.88E-147 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 CDC59_RS12185 6859a3f581ababb8ed6002dd3815ad47 471 PRINTS PR00145 Argininosuccinate lyase family signature 109 131 1.2E-68 T 29-03-2018 CDC59_RS12185 6859a3f581ababb8ed6002dd3815ad47 471 PRINTS PR00145 Argininosuccinate lyase family signature 239 263 1.2E-68 T 29-03-2018 CDC59_RS12185 6859a3f581ababb8ed6002dd3815ad47 471 PRINTS PR00145 Argininosuccinate lyase family signature 283 299 1.2E-68 T 29-03-2018 CDC59_RS12185 6859a3f581ababb8ed6002dd3815ad47 471 PRINTS PR00145 Argininosuccinate lyase family signature 201 217 1.2E-68 T 29-03-2018 CDC59_RS12185 6859a3f581ababb8ed6002dd3815ad47 471 PRINTS PR00145 Argininosuccinate lyase family signature 150 170 1.2E-68 T 29-03-2018 CDC59_RS12185 6859a3f581ababb8ed6002dd3815ad47 471 PRINTS PR00145 Argininosuccinate lyase family signature 318 337 1.2E-68 T 29-03-2018 CDC59_RS12185 6859a3f581ababb8ed6002dd3815ad47 471 PRINTS PR00149 Fumarate lyase superfamily signature 283 299 7.8E-30 T 29-03-2018 IPR000362 Fumarate lyase family CDC59_RS12185 6859a3f581ababb8ed6002dd3815ad47 471 PRINTS PR00149 Fumarate lyase superfamily signature 155 173 7.8E-30 T 29-03-2018 IPR000362 Fumarate lyase family CDC59_RS12185 6859a3f581ababb8ed6002dd3815ad47 471 PRINTS PR00149 Fumarate lyase superfamily signature 110 128 7.8E-30 T 29-03-2018 IPR000362 Fumarate lyase family CDC59_RS12185 6859a3f581ababb8ed6002dd3815ad47 471 PRINTS PR00149 Fumarate lyase superfamily signature 239 266 7.8E-30 T 29-03-2018 IPR000362 Fumarate lyase family CDC59_RS12185 6859a3f581ababb8ed6002dd3815ad47 471 Pfam PF14698 Argininosuccinate lyase C-terminal 371 445 1.6E-23 T 29-03-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CDC59_RS01865 ca6568212d2a352622fa0cfff08f842c 275 Gene3D G3DSA:1.10.1660.10 163 267 0.23 T 29-03-2018 CDC59_RS01865 ca6568212d2a352622fa0cfff08f842c 275 Gene3D G3DSA:1.10.1660.10 76 124 0.079 T 29-03-2018 CDC59_RS01865 ca6568212d2a352622fa0cfff08f842c 275 SMART SM00422 21 89 3.4E-9 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CDC59_RS01865 ca6568212d2a352622fa0cfff08f842c 275 Pfam PF13411 MerR HTH family regulatory protein 21 88 7.1E-18 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CDC59_RS01865 ca6568212d2a352622fa0cfff08f842c 275 Gene3D G3DSA:1.10.1660.10 17 75 3.8E-15 T 29-03-2018 CDC59_RS01865 ca6568212d2a352622fa0cfff08f842c 275 SUPERFAMILY SSF46955 21 93 5.13E-15 T 29-03-2018 IPR009061 Putative DNA-binding domain CDC59_RS05425 4abd85836d4aa4793df52357d7170fb3 1262 Gene3D G3DSA:3.30.1330.60 1082 1253 1.7E-15 T 29-03-2018 IPR006665 OmpA-like domain CDC59_RS05425 4abd85836d4aa4793df52357d7170fb3 1262 Pfam PF05359 Domain of Unknown Function (DUF748) 873 1019 1.2E-39 T 29-03-2018 IPR008023 Protein of unknown function DUF748 CDC59_RS05425 4abd85836d4aa4793df52357d7170fb3 1262 Pfam PF05359 Domain of Unknown Function (DUF748) 615 766 2.5E-37 T 29-03-2018 IPR008023 Protein of unknown function DUF748 CDC59_RS05425 4abd85836d4aa4793df52357d7170fb3 1262 Pfam PF05359 Domain of Unknown Function (DUF748) 186 337 1.8E-26 T 29-03-2018 IPR008023 Protein of unknown function DUF748 CDC59_RS05425 4abd85836d4aa4793df52357d7170fb3 1262 Pfam PF05359 Domain of Unknown Function (DUF748) 403 552 5.4E-20 T 29-03-2018 IPR008023 Protein of unknown function DUF748 CDC59_RS02510 78230bda8eb80bb178787cd987b163da 487 Gene3D G3DSA:3.40.50.720 144 252 4.8E-24 T 29-03-2018 CDC59_RS02510 78230bda8eb80bb178787cd987b163da 487 PRINTS PR00419 Adrenodoxin reductase family signature 145 167 4.3E-20 T 29-03-2018 CDC59_RS02510 78230bda8eb80bb178787cd987b163da 487 PRINTS PR00419 Adrenodoxin reductase family signature 168 181 4.3E-20 T 29-03-2018 CDC59_RS02510 78230bda8eb80bb178787cd987b163da 487 PRINTS PR00419 Adrenodoxin reductase family signature 296 310 4.3E-20 T 29-03-2018 CDC59_RS02510 78230bda8eb80bb178787cd987b163da 487 Gene3D G3DSA:3.50.50.60 253 338 3.6E-25 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS02510 78230bda8eb80bb178787cd987b163da 487 SUPERFAMILY SSF51971 373 480 6.0E-11 T 29-03-2018 CDC59_RS02510 78230bda8eb80bb178787cd987b163da 487 SUPERFAMILY SSF51971 142 410 2.59E-67 T 29-03-2018 CDC59_RS02510 78230bda8eb80bb178787cd987b163da 487 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 145 468 9.6E-25 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS02510 78230bda8eb80bb178787cd987b163da 487 Gene3D G3DSA:3.50.50.60 346 481 2.2E-18 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS02510 78230bda8eb80bb178787cd987b163da 487 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 486 2.0E-220 T 29-03-2018 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 CDC59_RS02510 78230bda8eb80bb178787cd987b163da 487 SUPERFAMILY SSF46548 2 154 5.93E-40 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CDC59_RS02510 78230bda8eb80bb178787cd987b163da 487 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 24 131 2.2E-24 T 29-03-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 CDC59_RS02510 78230bda8eb80bb178787cd987b163da 487 Gene3D G3DSA:1.10.1060.10 6 143 1.9E-39 T 29-03-2018 CDC59_RS05475 7e9f4f3b06ef0b00e845c0cefe2af0d7 298 Gene3D G3DSA:3.40.50.720 7 178 1.1E-30 T 29-03-2018 CDC59_RS05475 7e9f4f3b06ef0b00e845c0cefe2af0d7 298 SUPERFAMILY SSF48179 180 287 9.52E-34 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CDC59_RS05475 7e9f4f3b06ef0b00e845c0cefe2af0d7 298 Gene3D G3DSA:1.10.3660.10 187 296 2.9E-29 T 29-03-2018 CDC59_RS05475 7e9f4f3b06ef0b00e845c0cefe2af0d7 298 Pfam PF02153 Prephenate dehydrogenase 22 278 1.5E-71 T 29-03-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 CDC59_RS05475 7e9f4f3b06ef0b00e845c0cefe2af0d7 298 SUPERFAMILY SSF51735 9 175 2.44E-48 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS16590 03d205fb33ba0c4c2ac805dc96b3879d 484 TIGRFAM TIGR00797 matE: MATE efflux family protein 29 431 4.1E-66 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CDC59_RS16590 03d205fb33ba0c4c2ac805dc96b3879d 484 Pfam PF01554 MatE 258 418 7.3E-23 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CDC59_RS16590 03d205fb33ba0c4c2ac805dc96b3879d 484 Pfam PF01554 MatE 29 190 3.2E-28 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CDC59_RS16590 03d205fb33ba0c4c2ac805dc96b3879d 484 PIRSF PIRSF006603 5 460 1.2E-103 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CDC59_RS22845 5bb3356dd80517fdba602ac918c088ae 433 Pfam PF07690 Major Facilitator Superfamily 31 391 7.9E-43 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDC59_RS22845 5bb3356dd80517fdba602ac918c088ae 433 Gene3D G3DSA:1.20.1250.20 16 226 3.5E-32 T 29-03-2018 CDC59_RS22845 5bb3356dd80517fdba602ac918c088ae 433 Gene3D G3DSA:1.20.1250.20 238 430 2.1E-21 T 29-03-2018 CDC59_RS22845 5bb3356dd80517fdba602ac918c088ae 433 SUPERFAMILY SSF103473 21 426 1.44E-76 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS21085 6376907f8760589ac18de74d1967fd29 232 Gene3D G3DSA:3.40.50.1000 1 230 2.4E-16 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS21085 6376907f8760589ac18de74d1967fd29 232 SUPERFAMILY SSF56784 5 228 1.16E-31 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS21085 6376907f8760589ac18de74d1967fd29 232 TIGRFAM TIGR01493 HAD-SF-IA-v2: HAD hydrolase, family IA, variant 2 8 185 4.0E-18 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDC59_RS07525 7b02cdbd8f9046ca93a7992675520aaf 328 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 35 43 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CDC59_RS07525 7b02cdbd8f9046ca93a7992675520aaf 328 PRINTS PR00410 Phenol hydroxylase reductase family signature 185 194 4.8E-17 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CDC59_RS07525 7b02cdbd8f9046ca93a7992675520aaf 328 PRINTS PR00410 Phenol hydroxylase reductase family signature 291 299 4.8E-17 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CDC59_RS07525 7b02cdbd8f9046ca93a7992675520aaf 328 PRINTS PR00410 Phenol hydroxylase reductase family signature 126 138 4.8E-17 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CDC59_RS07525 7b02cdbd8f9046ca93a7992675520aaf 328 PRINTS PR00410 Phenol hydroxylase reductase family signature 142 149 4.8E-17 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CDC59_RS07525 7b02cdbd8f9046ca93a7992675520aaf 328 PRINTS PR00410 Phenol hydroxylase reductase family signature 201 220 4.8E-17 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CDC59_RS07525 7b02cdbd8f9046ca93a7992675520aaf 328 PRINTS PR00410 Phenol hydroxylase reductase family signature 226 235 4.8E-17 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CDC59_RS07525 7b02cdbd8f9046ca93a7992675520aaf 328 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 8 76 3.6E-12 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CDC59_RS07525 7b02cdbd8f9046ca93a7992675520aaf 328 Gene3D G3DSA:2.40.30.10 97 182 2.6E-20 T 29-03-2018 CDC59_RS07525 7b02cdbd8f9046ca93a7992675520aaf 328 SUPERFAMILY SSF54292 3 96 2.1E-20 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CDC59_RS07525 7b02cdbd8f9046ca93a7992675520aaf 328 SUPERFAMILY SSF52343 194 324 5.5E-35 T 29-03-2018 CDC59_RS07525 7b02cdbd8f9046ca93a7992675520aaf 328 Gene3D G3DSA:3.10.20.30 1 94 1.7E-16 T 29-03-2018 IPR012675 Beta-grasp domain CDC59_RS07525 7b02cdbd8f9046ca93a7992675520aaf 328 Pfam PF00175 Oxidoreductase NAD-binding domain 203 304 1.3E-14 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CDC59_RS07525 7b02cdbd8f9046ca93a7992675520aaf 328 SUPERFAMILY SSF63380 98 191 1.51E-22 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CDC59_RS07525 7b02cdbd8f9046ca93a7992675520aaf 328 Pfam PF00970 Oxidoreductase FAD-binding domain 102 190 3.5E-12 T 29-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CDC59_RS07525 7b02cdbd8f9046ca93a7992675520aaf 328 Gene3D G3DSA:3.40.50.80 183 320 4.1E-24 T 29-03-2018 CDC59_RS08365 ae5c3a508f224524ef86eca1e0056201 465 Gene3D G3DSA:3.40.1160.10 34 318 1.3E-58 T 29-03-2018 CDC59_RS08365 ae5c3a508f224524ef86eca1e0056201 465 SUPERFAMILY SSF55729 320 442 3.9E-20 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDC59_RS08365 ae5c3a508f224524ef86eca1e0056201 465 Hamap MF_01105 Amino-acid acetyltransferase [argA]. 34 465 208.9 T 29-03-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 CDC59_RS08365 ae5c3a508f224524ef86eca1e0056201 465 TIGRFAM TIGR01890 N-Ac-Glu-synth: amino-acid N-acetyltransferase 36 465 1.3E-222 T 29-03-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 CDC59_RS08365 ae5c3a508f224524ef86eca1e0056201 465 SUPERFAMILY SSF53633 33 315 2.88E-67 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CDC59_RS08365 ae5c3a508f224524ef86eca1e0056201 465 Pfam PF00583 Acetyltransferase (GNAT) family 357 429 1.7E-8 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CDC59_RS08365 ae5c3a508f224524ef86eca1e0056201 465 Gene3D G3DSA:3.40.630.30 320 465 1.9E-23 T 29-03-2018 CDC59_RS08365 ae5c3a508f224524ef86eca1e0056201 465 PIRSF PIRSF000423 27 465 2.8E-192 T 29-03-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 CDC59_RS08365 ae5c3a508f224524ef86eca1e0056201 465 Pfam PF00696 Amino acid kinase family 53 290 2.0E-28 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CDC59_RS15105 bac15d01715dec6447023525202e6679 167 Gene3D G3DSA:2.150.10.10 2 131 3.1E-18 T 29-03-2018 CDC59_RS15105 bac15d01715dec6447023525202e6679 167 Pfam PF06594 Haemolysin-type calcium binding protein related domain 89 128 6.4E-8 T 29-03-2018 IPR010566 Haemolysin-type calcium binding-related CDC59_RS15105 bac15d01715dec6447023525202e6679 167 SUPERFAMILY SSF51120 12 125 6.41E-21 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal CDC59_RS15105 bac15d01715dec6447023525202e6679 167 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 17 35 - T 29-03-2018 IPR018511 Hemolysin-type calcium-binding conserved site CDC59_RS15105 bac15d01715dec6447023525202e6679 167 PRINTS PR00313 NodO calcium binding signature 9 20 3.6E-8 T 29-03-2018 CDC59_RS15105 bac15d01715dec6447023525202e6679 167 PRINTS PR00313 NodO calcium binding signature 39 48 3.6E-8 T 29-03-2018 CDC59_RS15105 bac15d01715dec6447023525202e6679 167 PRINTS PR00313 NodO calcium binding signature 21 29 3.6E-8 T 29-03-2018 CDC59_RS15105 bac15d01715dec6447023525202e6679 167 PRINTS PR00313 NodO calcium binding signature 30 38 3.6E-8 T 29-03-2018 CDC59_RS17745 08125d4d8ae330a6ce9f39895650433f 310 SUPERFAMILY SSF53474 21 306 1.65E-70 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS17745 08125d4d8ae330a6ce9f39895650433f 310 Gene3D G3DSA:3.40.50.1820 1 309 5.7E-59 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS17745 08125d4d8ae330a6ce9f39895650433f 310 Pfam PF07859 alpha/beta hydrolase fold 78 284 5.4E-72 T 29-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CDC59_RS00635 8641848f7c784f0f0601bf7d836420ca 562 SMART SM00388 307 372 1.6E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS00635 8641848f7c784f0f0601bf7d836420ca 562 SMART SM00387 429 559 6.3E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS00635 8641848f7c784f0f0601bf7d836420ca 562 Pfam PF00512 His Kinase A (phospho-acceptor) domain 308 372 1.6E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS00635 8641848f7c784f0f0601bf7d836420ca 562 Pfam PF08521 Two-component sensor kinase N-terminal 35 154 4.9E-18 T 29-03-2018 IPR013727 Two-component sensor kinase, N-terminal CDC59_RS00635 8641848f7c784f0f0601bf7d836420ca 562 Gene3D G3DSA:1.20.5.1040 21 76 1.4E-5 T 29-03-2018 CDC59_RS00635 8641848f7c784f0f0601bf7d836420ca 562 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 432 556 3.3E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS00635 8641848f7c784f0f0601bf7d836420ca 562 SUPERFAMILY SSF55874 361 557 1.14E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS00635 8641848f7c784f0f0601bf7d836420ca 562 PRINTS PR00344 Bacterial sensor protein C-terminal signature 479 493 1.2E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS00635 8641848f7c784f0f0601bf7d836420ca 562 PRINTS PR00344 Bacterial sensor protein C-terminal signature 515 533 1.2E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS00635 8641848f7c784f0f0601bf7d836420ca 562 PRINTS PR00344 Bacterial sensor protein C-terminal signature 497 507 1.2E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS00635 8641848f7c784f0f0601bf7d836420ca 562 Gene3D G3DSA:1.10.287.130 297 368 2.4E-10 T 29-03-2018 CDC59_RS00635 8641848f7c784f0f0601bf7d836420ca 562 SUPERFAMILY SSF47384 290 372 4.9E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS00635 8641848f7c784f0f0601bf7d836420ca 562 Gene3D G3DSA:3.30.565.10 383 559 3.3E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS04045 678045f31e036dd28583b2d2a307aa47 596 Gene3D G3DSA:3.40.1770.10 230 595 5.9E-155 T 29-03-2018 CDC59_RS04045 678045f31e036dd28583b2d2a307aa47 596 Gene3D G3DSA:3.40.1770.10 20 163 3.0E-30 T 29-03-2018 CDC59_RS04045 678045f31e036dd28583b2d2a307aa47 596 Pfam PF01175 Urocanase Rossmann-like domain 196 389 3.6E-68 T 29-03-2018 IPR035085 Urocanase, Rossmann-like domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CDC59_RS04045 678045f31e036dd28583b2d2a307aa47 596 ProSitePatterns PS01233 Urocanase signature. 482 497 - T 29-03-2018 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CDC59_RS04045 678045f31e036dd28583b2d2a307aa47 596 TIGRFAM TIGR01228 hutU: urocanate hydratase 196 594 7.4E-194 T 29-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CDC59_RS04045 678045f31e036dd28583b2d2a307aa47 596 PIRSF PIRSF001423 4 596 6.3E-290 T 29-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CDC59_RS04045 678045f31e036dd28583b2d2a307aa47 596 SUPERFAMILY SSF111326 15 595 3.27E-248 T 29-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CDC59_RS04045 678045f31e036dd28583b2d2a307aa47 596 Pfam PF17392 Urocanase C-terminal domain 392 586 6.6E-93 T 29-03-2018 IPR035401 Urocanase, C-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CDC59_RS04045 678045f31e036dd28583b2d2a307aa47 596 Hamap MF_00577 Urocanate hydratase [hutU]. 3 596 50.452 T 29-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CDC59_RS04045 678045f31e036dd28583b2d2a307aa47 596 Pfam PF17391 Urocanase N-terminal domain 22 148 7.9E-61 T 29-03-2018 IPR035400 Urocanase, N-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CDC59_RS17760 85591a851e0da4f5f17529eaf8689c27 415 ProSitePatterns PS00216 Sugar transport proteins signature 1. 281 298 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CDC59_RS17760 85591a851e0da4f5f17529eaf8689c27 415 SUPERFAMILY SSF103473 10 410 1.7E-72 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS17760 85591a851e0da4f5f17529eaf8689c27 415 ProSitePatterns PS00217 Sugar transport proteins signature 2. 111 136 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CDC59_RS17760 85591a851e0da4f5f17529eaf8689c27 415 Gene3D G3DSA:1.20.1250.20 5 206 2.2E-30 T 29-03-2018 CDC59_RS17760 85591a851e0da4f5f17529eaf8689c27 415 Pfam PF07690 Major Facilitator Superfamily 24 321 7.0E-35 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDC59_RS17760 85591a851e0da4f5f17529eaf8689c27 415 Gene3D G3DSA:1.20.1250.20 207 415 6.6E-24 T 29-03-2018 CDC59_RS12960 476d348f8141d1748110812112f5d611 339 PIRSF PIRSF026166 1 337 8.1E-107 T 29-03-2018 IPR016833 Putative sodium bile acid cotransporter CDC59_RS12960 476d348f8141d1748110812112f5d611 339 Pfam PF13593 SBF-like CPA transporter family (DUF4137) 11 321 3.6E-99 T 29-03-2018 IPR016833 Putative sodium bile acid cotransporter CDC59_RS21945 e156212b35df9c78be824e076d66d253 522 SUPERFAMILY SSF47170 51 158 1.57E-8 T 29-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 CDC59_RS21945 e156212b35df9c78be824e076d66d253 522 Gene3D G3DSA:1.10.287.1060 245 330 0.026 T 29-03-2018 CDC59_RS21945 e156212b35df9c78be824e076d66d253 522 Pfam PF00672 HAMP domain 214 266 1.6E-6 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CDC59_RS21945 e156212b35df9c78be824e076d66d253 522 SMART SM00283 271 518 1.4E-88 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CDC59_RS21945 e156212b35df9c78be824e076d66d253 522 Pfam PF02203 Tar ligand binding domain homologue 8 172 2.7E-26 T 29-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 CDC59_RS21945 e156212b35df9c78be824e076d66d253 522 SMART SM00304 214 270 4.4E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CDC59_RS21945 e156212b35df9c78be824e076d66d253 522 Gene3D G3DSA:1.10.287.950 331 522 1.2E-48 T 29-03-2018 CDC59_RS21945 e156212b35df9c78be824e076d66d253 522 Gene3D G3DSA:1.20.120.30 26 188 7.1E-23 T 29-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain CDC59_RS21945 e156212b35df9c78be824e076d66d253 522 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 7 32 1.3E-60 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS21945 e156212b35df9c78be824e076d66d253 522 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 398 427 1.3E-60 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS21945 e156212b35df9c78be824e076d66d253 522 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 292 321 1.3E-60 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS21945 e156212b35df9c78be824e076d66d253 522 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 446 475 1.3E-60 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS21945 e156212b35df9c78be824e076d66d253 522 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 369 396 1.3E-60 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS21945 e156212b35df9c78be824e076d66d253 522 SUPERFAMILY SSF58104 241 519 2.49E-72 T 29-03-2018 CDC59_RS21945 e156212b35df9c78be824e076d66d253 522 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 330 486 2.4E-52 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CDC59_RS15095 37a03281685b3bd3bc3e38414f63c04b 484 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 440 458 - T 29-03-2018 IPR018511 Hemolysin-type calcium-binding conserved site CDC59_RS15095 37a03281685b3bd3bc3e38414f63c04b 484 Pfam PF06594 Haemolysin-type calcium binding protein related domain 355 400 6.3E-10 T 29-03-2018 IPR010566 Haemolysin-type calcium binding-related CDC59_RS15095 37a03281685b3bd3bc3e38414f63c04b 484 Pfam PF06594 Haemolysin-type calcium binding protein related domain 4 30 1.4E-4 T 29-03-2018 IPR010566 Haemolysin-type calcium binding-related CDC59_RS15095 37a03281685b3bd3bc3e38414f63c04b 484 Pfam PF06594 Haemolysin-type calcium binding protein related domain 170 215 2.0E-10 T 29-03-2018 IPR010566 Haemolysin-type calcium binding-related CDC59_RS15095 37a03281685b3bd3bc3e38414f63c04b 484 PRINTS PR00313 NodO calcium binding signature 268 277 5.1E-12 T 29-03-2018 CDC59_RS15095 37a03281685b3bd3bc3e38414f63c04b 484 PRINTS PR00313 NodO calcium binding signature 259 267 5.1E-12 T 29-03-2018 CDC59_RS15095 37a03281685b3bd3bc3e38414f63c04b 484 PRINTS PR00313 NodO calcium binding signature 71 82 5.1E-12 T 29-03-2018 CDC59_RS15095 37a03281685b3bd3bc3e38414f63c04b 484 PRINTS PR00313 NodO calcium binding signature 101 109 5.1E-12 T 29-03-2018 CDC59_RS15095 37a03281685b3bd3bc3e38414f63c04b 484 Gene3D G3DSA:2.60.120.10 420 465 2.8E-4 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CDC59_RS15095 37a03281685b3bd3bc3e38414f63c04b 484 Gene3D G3DSA:2.60.120.10 236 271 5.5E-4 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CDC59_RS15095 37a03281685b3bd3bc3e38414f63c04b 484 Gene3D G3DSA:2.60.120.10 83 93 0.013 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CDC59_RS15095 37a03281685b3bd3bc3e38414f63c04b 484 SUPERFAMILY SSF51120 35 214 2.49E-31 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal CDC59_RS15095 37a03281685b3bd3bc3e38414f63c04b 484 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 97 115 - T 29-03-2018 IPR018511 Hemolysin-type calcium-binding conserved site CDC59_RS15095 37a03281685b3bd3bc3e38414f63c04b 484 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 295 310 0.026 T 29-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CDC59_RS15095 37a03281685b3bd3bc3e38414f63c04b 484 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 259 275 1.4E-5 T 29-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CDC59_RS15095 37a03281685b3bd3bc3e38414f63c04b 484 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 277 293 0.0062 T 29-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CDC59_RS15095 37a03281685b3bd3bc3e38414f63c04b 484 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 243 257 3.8 T 29-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CDC59_RS15095 37a03281685b3bd3bc3e38414f63c04b 484 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 110 125 0.026 T 29-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CDC59_RS15095 37a03281685b3bd3bc3e38414f63c04b 484 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 74 90 2.5E-5 T 29-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CDC59_RS15095 37a03281685b3bd3bc3e38414f63c04b 484 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 92 108 0.0094 T 29-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CDC59_RS15095 37a03281685b3bd3bc3e38414f63c04b 484 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 444 460 1.5E-5 T 29-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CDC59_RS15095 37a03281685b3bd3bc3e38414f63c04b 484 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 428 442 1.1 T 29-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CDC59_RS15095 37a03281685b3bd3bc3e38414f63c04b 484 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 58 72 3.8 T 29-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CDC59_RS15095 37a03281685b3bd3bc3e38414f63c04b 484 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 282 300 - T 29-03-2018 IPR018511 Hemolysin-type calcium-binding conserved site CDC59_RS15095 37a03281685b3bd3bc3e38414f63c04b 484 SUPERFAMILY SSF51120 391 463 3.79E-14 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal CDC59_RS15095 37a03281685b3bd3bc3e38414f63c04b 484 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 431 449 - T 29-03-2018 IPR018511 Hemolysin-type calcium-binding conserved site CDC59_RS15095 37a03281685b3bd3bc3e38414f63c04b 484 Gene3D G3DSA:2.150.10.10 6 82 8.9E-17 T 29-03-2018 CDC59_RS15095 37a03281685b3bd3bc3e38414f63c04b 484 Gene3D G3DSA:2.150.10.10 272 380 1.1E-21 T 29-03-2018 CDC59_RS15095 37a03281685b3bd3bc3e38414f63c04b 484 Gene3D G3DSA:2.150.10.10 94 195 1.1E-21 T 29-03-2018 CDC59_RS15095 37a03281685b3bd3bc3e38414f63c04b 484 SUPERFAMILY SSF51120 221 398 2.88E-31 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal CDC59_RS05230 84d734c56bd4774157b3c66ae15d3263 560 SUPERFAMILY SSF53098 210 411 5.18E-48 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDC59_RS05230 84d734c56bd4774157b3c66ae15d3263 560 Gene3D G3DSA:3.30.420.10 200 419 2.8E-32 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDC59_RS05230 84d734c56bd4774157b3c66ae15d3263 560 Gene3D G3DSA:2.30.30.130 420 480 6.4E-12 T 29-03-2018 IPR015378 Transposase-like, Mu, C-terminal CDC59_RS05230 84d734c56bd4774157b3c66ae15d3263 560 Pfam PF09299 Mu transposase, C-terminal 428 477 4.6E-7 T 29-03-2018 IPR015378 Transposase-like, Mu, C-terminal CDC59_RS05230 84d734c56bd4774157b3c66ae15d3263 560 ProDom PD223702 DNA TRANSPOSASE DNA-BINDING TRANSPOSABLE INTEGRATION ELEMENT RECOMBINATION TRANSPOSASE EXCISION TRANSPOSITION 219 298 0.008 T 29-03-2018 CDC59_RS05230 84d734c56bd4774157b3c66ae15d3263 560 SUPERFAMILY SSF50610 417 481 1.57E-8 T 29-03-2018 IPR009004 Transposase, Mu, C-terminal CDC59_RS05230 84d734c56bd4774157b3c66ae15d3263 560 Pfam PF00665 Integrase core domain 235 337 2.0E-16 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CDC59_RS11185 5cd158b20a49195aff27ada2b10b7570 333 SMART SM00382 51 243 3.8E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS11185 5cd158b20a49195aff27ada2b10b7570 333 SUPERFAMILY SSF52540 51 327 2.02E-69 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS11185 5cd158b20a49195aff27ada2b10b7570 333 Pfam PF00005 ABC transporter 43 193 1.0E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS11185 5cd158b20a49195aff27ada2b10b7570 333 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 243 329 3.4E-27 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CDC59_RS11185 5cd158b20a49195aff27ada2b10b7570 333 ProSitePatterns PS00211 ABC transporters family signature. 166 180 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS11185 5cd158b20a49195aff27ada2b10b7570 333 Gene3D G3DSA:3.40.50.300 2 333 6.5E-82 T 29-03-2018 CDC59_RS11185 5cd158b20a49195aff27ada2b10b7570 333 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 245 309 1.3E-18 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CDC59_RS11050 41fb5d920438f21ce4e4ba7121791648 412 PRINTS PR00092 Tyrosinase copper-binding domain signature 299 317 3.2E-11 T 29-03-2018 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 Reactome: R-HSA-5662702 CDC59_RS11050 41fb5d920438f21ce4e4ba7121791648 412 PRINTS PR00092 Tyrosinase copper-binding domain signature 163 180 3.2E-11 T 29-03-2018 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 Reactome: R-HSA-5662702 CDC59_RS11050 41fb5d920438f21ce4e4ba7121791648 412 PRINTS PR00092 Tyrosinase copper-binding domain signature 192 197 3.2E-11 T 29-03-2018 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 Reactome: R-HSA-5662702 CDC59_RS11050 41fb5d920438f21ce4e4ba7121791648 412 Pfam PF00264 Common central domain of tyrosinase 145 320 6.2E-30 T 29-03-2018 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 Reactome: R-HSA-5662702 CDC59_RS11050 41fb5d920438f21ce4e4ba7121791648 412 Gene3D G3DSA:1.10.1280.10 114 412 5.5E-55 T 29-03-2018 IPR008922 Uncharacterised domain, di-copper centre Reactome: R-HSA-5662702 CDC59_RS11050 41fb5d920438f21ce4e4ba7121791648 412 ProSitePatterns PS00498 Tyrosinase and hemocyanins CuB-binding region signature. 300 311 - T 29-03-2018 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 Reactome: R-HSA-5662702 CDC59_RS11050 41fb5d920438f21ce4e4ba7121791648 412 ProSitePatterns PS00497 Tyrosinase CuA-binding region signature. 163 180 - T 29-03-2018 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 Reactome: R-HSA-5662702 CDC59_RS11050 41fb5d920438f21ce4e4ba7121791648 412 SUPERFAMILY SSF48056 92 410 1.83E-51 T 29-03-2018 IPR008922 Uncharacterised domain, di-copper centre Reactome: R-HSA-5662702 CDC59_RS03575 03f9713c4a9e593d2006f144946aa05b 877 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 433 588 7.8E-8 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDC59_RS03575 03f9713c4a9e593d2006f144946aa05b 877 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 635 675 2.6E-6 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDC59_RS03575 03f9713c4a9e593d2006f144946aa05b 877 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 48 59 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDC59_RS03575 03f9713c4a9e593d2006f144946aa05b 877 Pfam PF08264 Anticodon-binding domain of tRNA 717 839 6.4E-15 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CDC59_RS03575 03f9713c4a9e593d2006f144946aa05b 877 PRINTS PR00985 Leucyl-tRNA synthetase signature 220 239 3.4E-50 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CDC59_RS03575 03f9713c4a9e593d2006f144946aa05b 877 PRINTS PR00985 Leucyl-tRNA synthetase signature 573 583 3.4E-50 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CDC59_RS03575 03f9713c4a9e593d2006f144946aa05b 877 PRINTS PR00985 Leucyl-tRNA synthetase signature 540 562 3.4E-50 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CDC59_RS03575 03f9713c4a9e593d2006f144946aa05b 877 PRINTS PR00985 Leucyl-tRNA synthetase signature 503 521 3.4E-50 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CDC59_RS03575 03f9713c4a9e593d2006f144946aa05b 877 PRINTS PR00985 Leucyl-tRNA synthetase signature 191 204 3.4E-50 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CDC59_RS03575 03f9713c4a9e593d2006f144946aa05b 877 PRINTS PR00985 Leucyl-tRNA synthetase signature 159 175 3.4E-50 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CDC59_RS03575 03f9713c4a9e593d2006f144946aa05b 877 PRINTS PR00985 Leucyl-tRNA synthetase signature 133 150 3.4E-50 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CDC59_RS03575 03f9713c4a9e593d2006f144946aa05b 877 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 4 877 22.939 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CDC59_RS03575 03f9713c4a9e593d2006f144946aa05b 877 SUPERFAMILY SSF50677 231 430 7.74E-52 T 29-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CDC59_RS03575 03f9713c4a9e593d2006f144946aa05b 877 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 226 418 3.4E-66 T 29-03-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 CDC59_RS03575 03f9713c4a9e593d2006f144946aa05b 877 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 6 876 0.0 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CDC59_RS03575 03f9713c4a9e593d2006f144946aa05b 877 Gene3D G3DSA:3.40.50.620 2 664 3.0E-154 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDC59_RS03575 03f9713c4a9e593d2006f144946aa05b 877 Gene3D G3DSA:1.10.730.10 665 814 1.0E-28 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDC59_RS03575 03f9713c4a9e593d2006f144946aa05b 877 Pfam PF09334 tRNA synthetases class I (M) 44 177 1.4E-18 T 29-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDC59_RS03575 03f9713c4a9e593d2006f144946aa05b 877 SUPERFAMILY SSF52374 432 684 2.04E-146 T 29-03-2018 CDC59_RS03575 03f9713c4a9e593d2006f144946aa05b 877 SUPERFAMILY SSF52374 4 231 2.04E-146 T 29-03-2018 CDC59_RS03575 03f9713c4a9e593d2006f144946aa05b 877 SUPERFAMILY SSF47323 679 876 2.62E-34 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDC59_RS11065 8d3efe89419a6a136ab81e853c409a9a 69 Pfam PF07825 Excisionase-like protein 2 60 2.9E-17 T 29-03-2018 IPR012884 Excisionase-like GO:0003677|GO:0006310 CDC59_RS11065 8d3efe89419a6a136ab81e853c409a9a 69 SUPERFAMILY SSF46955 2 56 1.74E-19 T 29-03-2018 IPR009061 Putative DNA-binding domain CDC59_RS11065 8d3efe89419a6a136ab81e853c409a9a 69 Gene3D G3DSA:1.10.1660.20 3 66 9.3E-23 T 29-03-2018 CDC59_RS00820 98a1243e930a9b090eafdb6d4ba12907 293 Pfam PF00119 ATP synthase A chain 51 286 6.2E-53 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS00820 98a1243e930a9b090eafdb6d4ba12907 293 Hamap MF_01393 ATP synthase subunit a [atpB]. 36 293 13.978 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS00820 98a1243e930a9b090eafdb6d4ba12907 293 ProSitePatterns PS00449 ATP synthase a subunit signature. 216 225 - T 29-03-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS00820 98a1243e930a9b090eafdb6d4ba12907 293 SUPERFAMILY SSF81336 102 287 1.83E-38 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS00820 98a1243e930a9b090eafdb6d4ba12907 293 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 43 288 7.5E-42 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS00820 98a1243e930a9b090eafdb6d4ba12907 293 Gene3D G3DSA:1.20.120.220 100 293 2.0E-42 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS04120 96649c05a35ce4e2e3804dea4b53c1df 228 SUPERFAMILY SSF52540 7 226 1.39E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS04120 96649c05a35ce4e2e3804dea4b53c1df 228 SMART SM00382 33 226 2.8E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS04120 96649c05a35ce4e2e3804dea4b53c1df 228 Gene3D G3DSA:3.40.50.300 2 228 2.4E-46 T 29-03-2018 CDC59_RS04120 96649c05a35ce4e2e3804dea4b53c1df 228 Pfam PF00005 ABC transporter 29 171 7.0E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS22760 ac9d2a20ffbeec0c085cf47724b8e3a3 351 Hamap MF_00524 Glucokinase [glk]. 20 346 34.758 T 29-03-2018 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 CDC59_RS22760 ac9d2a20ffbeec0c085cf47724b8e3a3 351 Gene3D G3DSA:3.30.420.40 12 129 8.7E-15 T 29-03-2018 CDC59_RS22760 ac9d2a20ffbeec0c085cf47724b8e3a3 351 Pfam PF02685 Glucokinase 22 345 1.1E-110 T 29-03-2018 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 CDC59_RS22760 ac9d2a20ffbeec0c085cf47724b8e3a3 351 TIGRFAM TIGR00749 glk: glucokinase 22 338 5.5E-101 T 29-03-2018 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 CDC59_RS22760 ac9d2a20ffbeec0c085cf47724b8e3a3 351 SUPERFAMILY SSF53067 22 342 5.05E-47 T 29-03-2018 CDC59_RS22760 ac9d2a20ffbeec0c085cf47724b8e3a3 351 Gene3D G3DSA:3.40.367.20 130 329 1.1E-28 T 29-03-2018 CDC59_RS10900 d815fdade3bf648fa2edc67dd20f5727 237 Gene3D G3DSA:3.40.50.2300 3 125 1.2E-34 T 29-03-2018 CDC59_RS10900 d815fdade3bf648fa2edc67dd20f5727 237 Pfam PF00072 Response regulator receiver domain 5 117 1.8E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS10900 d815fdade3bf648fa2edc67dd20f5727 237 SUPERFAMILY SSF46894 124 232 2.15E-28 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CDC59_RS10900 d815fdade3bf648fa2edc67dd20f5727 237 SMART SM00862 154 231 1.9E-29 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDC59_RS10900 d815fdade3bf648fa2edc67dd20f5727 237 Gene3D G3DSA:1.10.10.10 126 237 8.9E-33 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS10900 d815fdade3bf648fa2edc67dd20f5727 237 SMART SM00448 3 116 2.9E-39 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS10900 d815fdade3bf648fa2edc67dd20f5727 237 Pfam PF00486 Transcriptional regulatory protein, C terminal 159 231 7.3E-27 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDC59_RS10900 d815fdade3bf648fa2edc67dd20f5727 237 SUPERFAMILY SSF52172 3 126 4.41E-42 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS10900 d815fdade3bf648fa2edc67dd20f5727 237 TIGRFAM TIGR02154 PhoB: phosphate regulon transcriptional regulatory protein PhoB 2 231 3.3E-104 T 29-03-2018 IPR011879 Signal transduction response regulator, phosphate regulon transcriptional regulatory protein PhoB GO:0000156|GO:0000160|GO:0003677|GO:0006817 CDC59_RS10310 b825aab792e25fdbda5cdf6ba1a8646b 326 Pfam PF01207 Dihydrouridine synthase (Dus) 6 270 3.1E-66 T 29-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CDC59_RS10310 b825aab792e25fdbda5cdf6ba1a8646b 326 PIRSF PIRSF006621 1 322 8.4E-87 T 29-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CDC59_RS10310 b825aab792e25fdbda5cdf6ba1a8646b 326 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 93 111 - T 29-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 CDC59_RS10310 b825aab792e25fdbda5cdf6ba1a8646b 326 Hamap MF_02043 tRNA-dihydrouridine(16) synthase [dusC]. 9 314 50.765 T 29-03-2018 IPR032886 tRNA-dihydrouridine(16) synthase GO:0002943|GO:0017150 CDC59_RS10310 b825aab792e25fdbda5cdf6ba1a8646b 326 SUPERFAMILY SSF51395 3 316 2.75E-67 T 29-03-2018 CDC59_RS10310 b825aab792e25fdbda5cdf6ba1a8646b 326 Gene3D G3DSA:3.20.20.70 1 242 3.4E-44 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS08555 7cf20b8678d7de0ac1a34ef4d24e9d66 162 Pfam PF17384 RimP C-terminal SH3 domain 77 149 1.6E-20 T 29-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal CDC59_RS08555 7cf20b8678d7de0ac1a34ef4d24e9d66 162 Gene3D G3DSA:2.30.30.180 78 147 4.4E-17 T 29-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal CDC59_RS08555 7cf20b8678d7de0ac1a34ef4d24e9d66 162 SUPERFAMILY SSF74942 75 150 1.03E-12 T 29-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal CDC59_RS08555 7cf20b8678d7de0ac1a34ef4d24e9d66 162 Gene3D G3DSA:3.30.300.70 1 71 8.9E-20 T 29-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal CDC59_RS08555 7cf20b8678d7de0ac1a34ef4d24e9d66 162 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 1 150 21.241 T 29-03-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 CDC59_RS08555 7cf20b8678d7de0ac1a34ef4d24e9d66 162 SUPERFAMILY SSF75420 3 74 1.44E-14 T 29-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal CDC59_RS08555 7cf20b8678d7de0ac1a34ef4d24e9d66 162 Pfam PF02576 RimP N-terminal domain 6 74 1.3E-19 T 29-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal CDC59_RS19100 e2947e9d2a0d84128e6bb9e5f5fa1e2c 383 TIGRFAM TIGR00312 cbiD: cobalamin biosynthesis protein CbiD 26 372 3.9E-64 T 29-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 CDC59_RS19100 e2947e9d2a0d84128e6bb9e5f5fa1e2c 383 Gene3D G3DSA:3.30.2110.10 21 194 5.8E-57 T 29-03-2018 CDC59_RS19100 e2947e9d2a0d84128e6bb9e5f5fa1e2c 383 Hamap MF_00787 Cobalt-precorrin-5B C(1)-methyltransferase [cbiD]. 19 377 26.81 T 29-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 CDC59_RS19100 e2947e9d2a0d84128e6bb9e5f5fa1e2c 383 PIRSF PIRSF026782 16 382 2.4E-116 T 29-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 CDC59_RS19100 e2947e9d2a0d84128e6bb9e5f5fa1e2c 383 Pfam PF01888 CbiD 19 285 3.4E-80 T 29-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 CDC59_RS19100 e2947e9d2a0d84128e6bb9e5f5fa1e2c 383 SUPERFAMILY SSF111342 12 302 7.06E-74 T 29-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 CDC59_RS02965 3fc566a62092e0b539eec1bbd9cc6e4b 258 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 257 1.6E-82 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CDC59_RS02965 3fc566a62092e0b539eec1bbd9cc6e4b 258 SUPERFAMILY SSF52096 1 258 1.76E-90 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CDC59_RS02965 3fc566a62092e0b539eec1bbd9cc6e4b 258 Gene3D G3DSA:3.90.226.10 2 218 1.2E-73 T 29-03-2018 CDC59_RS02965 3fc566a62092e0b539eec1bbd9cc6e4b 258 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 99 119 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CDC59_RS02965 3fc566a62092e0b539eec1bbd9cc6e4b 258 Gene3D G3DSA:1.10.12.10 219 256 1.3E-23 T 29-03-2018 IPR014748 Crontonase, C-terminal CDC59_RS04870 d6b7937a78325e2c187e51c38a192969 209 Hamap MF_01969 Kynurenine formamidase [kynB]. 4 208 45.171 T 29-03-2018 IPR017484 Kynurenine formamidase, bacteria GO:0004328|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 CDC59_RS04870 d6b7937a78325e2c187e51c38a192969 209 TIGRFAM TIGR03035 trp_arylform: arylformamidase 5 208 2.0E-104 T 29-03-2018 IPR017484 Kynurenine formamidase, bacteria GO:0004328|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 CDC59_RS04870 d6b7937a78325e2c187e51c38a192969 209 SUPERFAMILY SSF102198 4 206 2.62E-56 T 29-03-2018 CDC59_RS04870 d6b7937a78325e2c187e51c38a192969 209 Gene3D G3DSA:3.50.30.50 2 207 2.6E-47 T 29-03-2018 CDC59_RS04870 d6b7937a78325e2c187e51c38a192969 209 Pfam PF04199 Putative cyclase 7 151 3.5E-17 T 29-03-2018 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 CDC59_RS13545 098e6d6ba842bbb025265e025ab28b77 578 Gene3D G3DSA:3.30.300.30 467 566 3.7E-23 T 29-03-2018 CDC59_RS13545 098e6d6ba842bbb025265e025ab28b77 578 Gene3D G3DSA:3.40.50.980 30 228 1.8E-39 T 29-03-2018 CDC59_RS13545 098e6d6ba842bbb025265e025ab28b77 578 Pfam PF13193 AMP-binding enzyme C-terminal domain 482 557 2.7E-15 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CDC59_RS13545 098e6d6ba842bbb025265e025ab28b77 578 SUPERFAMILY SSF56801 27 160 1.26E-134 T 29-03-2018 CDC59_RS13545 098e6d6ba842bbb025265e025ab28b77 578 SUPERFAMILY SSF56801 192 567 1.26E-134 T 29-03-2018 CDC59_RS13545 098e6d6ba842bbb025265e025ab28b77 578 Pfam PF00501 AMP-binding enzyme 40 473 1.4E-95 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CDC59_RS13545 098e6d6ba842bbb025265e025ab28b77 578 Gene3D G3DSA:2.30.38.10 384 466 1.0E-25 T 29-03-2018 CDC59_RS13545 098e6d6ba842bbb025265e025ab28b77 578 Gene3D G3DSA:3.40.50.980 229 383 1.4E-35 T 29-03-2018 CDC59_RS10125 14d52d64af98dc169daaeb2547bcf620 531 PIRSF PIRSF017184 25 529 4.6E-105 T 29-03-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 CDC59_RS10125 14d52d64af98dc169daaeb2547bcf620 531 Gene3D G3DSA:3.40.1190.20 248 521 1.6E-39 T 29-03-2018 IPR029056 Ribokinase-like CDC59_RS10125 14d52d64af98dc169daaeb2547bcf620 531 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 246 526 21.762 T 29-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CDC59_RS10125 14d52d64af98dc169daaeb2547bcf620 531 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 45 226 1.1E-28 T 29-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CDC59_RS10125 14d52d64af98dc169daaeb2547bcf620 531 SUPERFAMILY SSF64153 26 267 2.09E-52 T 29-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CDC59_RS10125 14d52d64af98dc169daaeb2547bcf620 531 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 252 500 5.9E-57 T 29-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CDC59_RS10125 14d52d64af98dc169daaeb2547bcf620 531 Gene3D G3DSA:3.40.50.10260 24 247 9.2E-53 T 29-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CDC59_RS10125 14d52d64af98dc169daaeb2547bcf620 531 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 460 470 - T 29-03-2018 IPR017953 Carbohydrate kinase, predicted, conserved site CDC59_RS10125 14d52d64af98dc169daaeb2547bcf620 531 Pfam PF03853 YjeF-related protein N-terminus 46 209 2.1E-37 T 29-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CDC59_RS10125 14d52d64af98dc169daaeb2547bcf620 531 Pfam PF01256 Carbohydrate kinase 269 499 3.3E-49 T 29-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CDC59_RS10125 14d52d64af98dc169daaeb2547bcf620 531 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 26 230 20.878 T 29-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CDC59_RS10125 14d52d64af98dc169daaeb2547bcf620 531 SUPERFAMILY SSF53613 245 513 6.37E-60 T 29-03-2018 IPR029056 Ribokinase-like CDC59_RS10895 b075efc79b716aa204e9c5c721ca994d 443 SUPERFAMILY SSF55874 261 425 5.76E-41 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS10895 b075efc79b716aa204e9c5c721ca994d 443 SUPERFAMILY SSF55785 92 198 2.86E-7 T 29-03-2018 IPR000014 PAS domain CDC59_RS10895 b075efc79b716aa204e9c5c721ca994d 443 SUPERFAMILY SSF47384 194 271 9.61E-20 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS10895 b075efc79b716aa204e9c5c721ca994d 443 Gene3D G3DSA:3.30.565.10 284 441 1.8E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS10895 b075efc79b716aa204e9c5c721ca994d 443 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 318 427 2.0E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS10895 b075efc79b716aa204e9c5c721ca994d 443 SMART SM00388 206 272 3.4E-22 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS10895 b075efc79b716aa204e9c5c721ca994d 443 Pfam PF00512 His Kinase A (phospho-acceptor) domain 206 271 3.3E-20 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS10895 b075efc79b716aa204e9c5c721ca994d 443 TIGRFAM TIGR02966 phoR_proteo: phosphate regulon sensor kinase PhoR 94 424 2.7E-137 T 29-03-2018 IPR014310 Signal transduction histidine kinase, phosphate regulon sensor PhoR GO:0000155|GO:0000160|GO:0004673|GO:0016021 CDC59_RS10895 b075efc79b716aa204e9c5c721ca994d 443 Gene3D G3DSA:1.10.287.130 212 267 9.0E-19 T 29-03-2018 CDC59_RS10895 b075efc79b716aa204e9c5c721ca994d 443 SMART SM00387 316 428 5.9E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS10895 b075efc79b716aa204e9c5c721ca994d 443 Gene3D G3DSA:3.30.450.20 95 211 4.2E-10 T 29-03-2018 CDC59_RS10895 b075efc79b716aa204e9c5c721ca994d 443 SMART SM00091 98 164 0.0051 T 29-03-2018 IPR000014 PAS domain CDC59_RS10895 b075efc79b716aa204e9c5c721ca994d 443 Pfam PF11808 Domain of unknown function (DUF3329) 5 89 2.5E-15 T 29-03-2018 IPR021766 Protein of unknown function DUF3329 GO:0004673 CDC59_RS10895 b075efc79b716aa204e9c5c721ca994d 443 PRINTS PR00344 Bacterial sensor protein C-terminal signature 388 406 2.2E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS10895 b075efc79b716aa204e9c5c721ca994d 443 PRINTS PR00344 Bacterial sensor protein C-terminal signature 412 425 2.2E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS10895 b075efc79b716aa204e9c5c721ca994d 443 PRINTS PR00344 Bacterial sensor protein C-terminal signature 353 367 2.2E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS10895 b075efc79b716aa204e9c5c721ca994d 443 PRINTS PR00344 Bacterial sensor protein C-terminal signature 371 381 2.2E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS10895 b075efc79b716aa204e9c5c721ca994d 443 Pfam PF13188 PAS domain 99 154 7.1E-6 T 29-03-2018 IPR000014 PAS domain CDC59_RS13995 189be29ca7198bf4c8352a9ca5074ef0 415 Pfam PF07670 Nucleoside recognition 50 155 1.1E-8 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CDC59_RS13995 189be29ca7198bf4c8352a9ca5074ef0 415 Pfam PF07670 Nucleoside recognition 282 385 3.7E-7 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CDC59_RS13995 189be29ca7198bf4c8352a9ca5074ef0 415 PIRSF PIRSF036542 2 415 2.7E-204 T 29-03-2018 IPR011415 Predicted bifunctional spore maturation protein, fused SpmA/SpmB CDC59_RS00600 4788a1b18d1b73558e9cb040a91443f3 246 Hamap MF_00267 Probable septum site-determining protein MinC [minC]. 8 244 26.815 T 29-03-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 CDC59_RS00600 4788a1b18d1b73558e9cb040a91443f3 246 Gene3D G3DSA:2.160.20.70 128 246 6.7E-33 T 29-03-2018 CDC59_RS00600 4788a1b18d1b73558e9cb040a91443f3 246 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 140 240 1.0E-29 T 29-03-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 CDC59_RS00600 4788a1b18d1b73558e9cb040a91443f3 246 TIGRFAM TIGR01222 minC: septum site-determining protein MinC 9 243 1.8E-49 T 29-03-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 CDC59_RS00600 4788a1b18d1b73558e9cb040a91443f3 246 Pfam PF05209 Septum formation inhibitor MinC, N-terminal domain 6 104 7.0E-8 T 29-03-2018 IPR007874 Septum formation inhibitor MinC, N-terminal GO:0051302 CDC59_RS00600 4788a1b18d1b73558e9cb040a91443f3 246 SUPERFAMILY SSF63848 138 244 8.37E-32 T 29-03-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 CDC59_RS14490 d4066cf6a8de67e69c39f6ea804ca23e 338 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 192 213 - T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CDC59_RS14490 d4066cf6a8de67e69c39f6ea804ca23e 338 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 1 326 34.775 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CDC59_RS14490 d4066cf6a8de67e69c39f6ea804ca23e 338 SUPERFAMILY SSF51735 1 184 6.65E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS14490 d4066cf6a8de67e69c39f6ea804ca23e 338 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3 162 1.1E-33 T 29-03-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CDC59_RS14490 d4066cf6a8de67e69c39f6ea804ca23e 338 Gene3D G3DSA:1.10.1040.10 193 338 1.3E-51 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CDC59_RS14490 d4066cf6a8de67e69c39f6ea804ca23e 338 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 184 324 3.2E-49 T 29-03-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CDC59_RS14490 d4066cf6a8de67e69c39f6ea804ca23e 338 PIRSF PIRSF000114 1 336 4.2E-94 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CDC59_RS14490 d4066cf6a8de67e69c39f6ea804ca23e 338 Gene3D G3DSA:3.40.50.720 1 183 6.4E-29 T 29-03-2018 CDC59_RS14490 d4066cf6a8de67e69c39f6ea804ca23e 338 SUPERFAMILY SSF48179 183 335 3.57E-53 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CDC59_RS02430 8f07ef45c1547536c3bfd2e584bffa58 217 Pfam PF01794 Ferric reductase like transmembrane component 50 164 3.5E-18 T 29-03-2018 IPR013130 Ferric reductase transmembrane component-like domain CDC59_RS02430 8f07ef45c1547536c3bfd2e584bffa58 217 Hamap MF_01207 Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ [msrQ]. 10 206 20.905 T 29-03-2018 IPR022837 Protein-methionine-sulfoxide reductase subunit MsrQ GO:0005887|GO:0030091 CDC59_RS00310 92c5d2270ffd46942ebe675eee2e82c4 436 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 121 130 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CDC59_RS00310 92c5d2270ffd46942ebe675eee2e82c4 436 SUPERFAMILY SSF55031 229 340 2.09E-21 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CDC59_RS00310 92c5d2270ffd46942ebe675eee2e82c4 436 PIRSF PIRSF037238 35 428 8.3E-102 T 29-03-2018 IPR017150 Peptidase M20, glutamate carboxypeptidase CDC59_RS00310 92c5d2270ffd46942ebe675eee2e82c4 436 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 153 192 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CDC59_RS00310 92c5d2270ffd46942ebe675eee2e82c4 436 SUPERFAMILY SSF53187 349 426 6.0E-47 T 29-03-2018 CDC59_RS00310 92c5d2270ffd46942ebe675eee2e82c4 436 SUPERFAMILY SSF53187 36 237 6.0E-47 T 29-03-2018 CDC59_RS00310 92c5d2270ffd46942ebe675eee2e82c4 436 Pfam PF07687 Peptidase dimerisation domain 227 325 5.7E-20 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CDC59_RS00310 92c5d2270ffd46942ebe675eee2e82c4 436 Pfam PF01546 Peptidase family M20/M25/M40 122 425 3.2E-27 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CDC59_RS00310 92c5d2270ffd46942ebe675eee2e82c4 436 Gene3D G3DSA:3.40.630.10 28 431 4.4E-50 T 29-03-2018 CDC59_RS15025 1b9878878e7d70e622f8251a92452d5f 309 ProSitePatterns PS01062 Hydroxymethylglutaryl-coenzyme A lyase active site. 233 242 - T 29-03-2018 IPR000138 Hydroxymethylglutaryl-CoA lyase, active site GO:0004419 KEGG: 00072+4.1.3.4|KEGG: 00280+4.1.3.4|KEGG: 00281+4.1.3.4|KEGG: 00650+4.1.3.4|MetaCyc: PWY-5074|Reactome: R-HSA-77111 CDC59_RS15025 1b9878878e7d70e622f8251a92452d5f 309 Pfam PF00682 HMGL-like 7 279 2.6E-52 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CDC59_RS15025 1b9878878e7d70e622f8251a92452d5f 309 SUPERFAMILY SSF51569 1 292 6.23E-70 T 29-03-2018 CDC59_RS15025 1b9878878e7d70e622f8251a92452d5f 309 Gene3D G3DSA:3.20.20.70 2 299 2.0E-106 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS13080 aa1263c3b0dbeaf5ab838a4136fc2c9f 307 Pfam PF04381 Putative exonuclease, RdgC 1 295 2.0E-115 T 29-03-2018 IPR007476 Putative exonuclease, RdgC GO:0006310 CDC59_RS13080 aa1263c3b0dbeaf5ab838a4136fc2c9f 307 Hamap MF_00194 Recombination-associated protein RdgC [rdgC]. 1 298 41.694 T 29-03-2018 IPR007476 Putative exonuclease, RdgC GO:0006310 CDC59_RS21200 b666d8b38aa17118236b1036548593d0 631 Hamap MF_01522 Low affinity potassium transport system protein kup [kup]. 11 631 33.992 T 29-03-2018 IPR023051 Potassium uptake protein, low affinity, Kup CDC59_RS21200 b666d8b38aa17118236b1036548593d0 631 Pfam PF02705 K+ potassium transporter 20 552 4.9E-207 T 29-03-2018 IPR003855 Potassium transporter GO:0015079|GO:0016020|GO:0071805 CDC59_RS00065 412ae1b203f77cca8d0a7e58ee9fe21f 1049 PRINTS PR00702 Acriflavin resistance protein family signature 621 635 9.4E-104 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS00065 412ae1b203f77cca8d0a7e58ee9fe21f 1049 PRINTS PR00702 Acriflavin resistance protein family signature 392 416 9.4E-104 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS00065 412ae1b203f77cca8d0a7e58ee9fe21f 1049 PRINTS PR00702 Acriflavin resistance protein family signature 364 385 9.4E-104 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS00065 412ae1b203f77cca8d0a7e58ee9fe21f 1049 PRINTS PR00702 Acriflavin resistance protein family signature 337 360 9.4E-104 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS00065 412ae1b203f77cca8d0a7e58ee9fe21f 1049 PRINTS PR00702 Acriflavin resistance protein family signature 446 469 9.4E-104 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS00065 412ae1b203f77cca8d0a7e58ee9fe21f 1049 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 9.4E-104 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS00065 412ae1b203f77cca8d0a7e58ee9fe21f 1049 PRINTS PR00702 Acriflavin resistance protein family signature 554 571 9.4E-104 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS00065 412ae1b203f77cca8d0a7e58ee9fe21f 1049 PRINTS PR00702 Acriflavin resistance protein family signature 471 494 9.4E-104 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS00065 412ae1b203f77cca8d0a7e58ee9fe21f 1049 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 9.4E-104 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS00065 412ae1b203f77cca8d0a7e58ee9fe21f 1049 Gene3D G3DSA:3.30.70.1430 569 668 7.7E-21 T 29-03-2018 CDC59_RS00065 412ae1b203f77cca8d0a7e58ee9fe21f 1049 Pfam PF00873 AcrB/AcrD/AcrF family 1 1026 0.0 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS00065 412ae1b203f77cca8d0a7e58ee9fe21f 1049 Gene3D G3DSA:3.30.2090.10 181 276 1.7E-18 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS00065 412ae1b203f77cca8d0a7e58ee9fe21f 1049 SUPERFAMILY SSF82693 38 132 3.66E-24 T 29-03-2018 CDC59_RS00065 412ae1b203f77cca8d0a7e58ee9fe21f 1049 SUPERFAMILY SSF82714 722 806 4.32E-21 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS00065 412ae1b203f77cca8d0a7e58ee9fe21f 1049 SUPERFAMILY SSF82866 807 1028 1.83E-43 T 29-03-2018 CDC59_RS00065 412ae1b203f77cca8d0a7e58ee9fe21f 1049 SUPERFAMILY SSF82714 183 272 1.12E-20 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS00065 412ae1b203f77cca8d0a7e58ee9fe21f 1049 Gene3D G3DSA:3.30.70.1440 672 768 8.7E-24 T 29-03-2018 CDC59_RS00065 412ae1b203f77cca8d0a7e58ee9fe21f 1049 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 1 1036 0.0 T 29-03-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 CDC59_RS00065 412ae1b203f77cca8d0a7e58ee9fe21f 1049 Gene3D G3DSA:1.20.1640.10 287 511 1.7E-48 T 29-03-2018 CDC59_RS00065 412ae1b203f77cca8d0a7e58ee9fe21f 1049 SUPERFAMILY SSF82693 567 670 5.23E-28 T 29-03-2018 CDC59_RS00065 412ae1b203f77cca8d0a7e58ee9fe21f 1049 Gene3D G3DSA:1.20.1640.10 815 1028 1.0E-36 T 29-03-2018 CDC59_RS00065 412ae1b203f77cca8d0a7e58ee9fe21f 1049 Gene3D G3DSA:3.30.70.1430 38 141 9.9E-27 T 29-03-2018 CDC59_RS00065 412ae1b203f77cca8d0a7e58ee9fe21f 1049 SUPERFAMILY SSF82866 299 498 1.7E-51 T 29-03-2018 CDC59_RS00065 412ae1b203f77cca8d0a7e58ee9fe21f 1049 SUPERFAMILY SSF82693 136 183 2.88E-25 T 29-03-2018 CDC59_RS00065 412ae1b203f77cca8d0a7e58ee9fe21f 1049 SUPERFAMILY SSF82693 275 331 2.88E-25 T 29-03-2018 CDC59_RS16530 eac34e8944687306ea5b5dd7e3526201 180 Gene3D G3DSA:3.30.70.60 80 180 5.8E-7 T 29-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 CDC59_RS03550 d84f948410f0d8caebe85dd2c17f70ae 332 SMART SM00846 3 151 5.6E-99 T 29-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDC59_RS03550 d84f948410f0d8caebe85dd2c17f70ae 332 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 156 313 5.7E-67 T 29-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDC59_RS03550 d84f948410f0d8caebe85dd2c17f70ae 332 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 324 3.4E-134 T 29-03-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDC59_RS03550 d84f948410f0d8caebe85dd2c17f70ae 332 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 103 2.4E-40 T 29-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDC59_RS03550 d84f948410f0d8caebe85dd2c17f70ae 332 PIRSF PIRSF000149 1 332 8.0E-132 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDC59_RS03550 d84f948410f0d8caebe85dd2c17f70ae 332 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 172 188 1.9E-46 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDC59_RS03550 d84f948410f0d8caebe85dd2c17f70ae 332 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 269 284 1.9E-46 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDC59_RS03550 d84f948410f0d8caebe85dd2c17f70ae 332 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 110 123 1.9E-46 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDC59_RS03550 d84f948410f0d8caebe85dd2c17f70ae 332 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 229 246 1.9E-46 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDC59_RS03550 d84f948410f0d8caebe85dd2c17f70ae 332 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 145 163 1.9E-46 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDC59_RS03550 d84f948410f0d8caebe85dd2c17f70ae 332 Gene3D G3DSA:3.30.360.10 161 315 5.5E-77 T 29-03-2018 CDC59_RS03550 d84f948410f0d8caebe85dd2c17f70ae 332 SUPERFAMILY SSF55347 150 313 2.35E-74 T 29-03-2018 CDC59_RS03550 d84f948410f0d8caebe85dd2c17f70ae 332 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 149 156 - T 29-03-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDC59_RS03550 d84f948410f0d8caebe85dd2c17f70ae 332 Gene3D G3DSA:3.40.50.720 1 160 6.0E-82 T 29-03-2018 CDC59_RS03550 d84f948410f0d8caebe85dd2c17f70ae 332 SUPERFAMILY SSF51735 3 167 1.74E-68 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS04210 7ba58601326f4b4bb37bc7002d2fe846 323 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 12 297 1.8E-88 T 29-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CDC59_RS04210 7ba58601326f4b4bb37bc7002d2fe846 323 Gene3D G3DSA:1.10.287.890 212 294 3.2E-25 T 29-03-2018 CDC59_RS04210 7ba58601326f4b4bb37bc7002d2fe846 323 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 11 321 28.764 T 29-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CDC59_RS04210 7ba58601326f4b4bb37bc7002d2fe846 323 SUPERFAMILY SSF52540 14 158 1.59E-17 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS04210 7ba58601326f4b4bb37bc7002d2fe846 323 Gene3D G3DSA:3.40.50.300 8 198 5.9E-62 T 29-03-2018 CDC59_RS04210 7ba58601326f4b4bb37bc7002d2fe846 323 Pfam PF01715 IPP transferase 45 297 1.2E-86 T 29-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CDC59_RS07260 0070efb70d5d1b3e9cae98105485f37d 219 Gene3D G3DSA:3.40.50.1000 77 219 1.7E-32 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS07260 0070efb70d5d1b3e9cae98105485f37d 219 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 91 180 2.8E-10 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDC59_RS07260 0070efb70d5d1b3e9cae98105485f37d 219 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 185 1.1E-33 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS07260 0070efb70d5d1b3e9cae98105485f37d 219 Gene3D G3DSA:1.10.150.240 32 76 8.5E-16 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CDC59_RS07260 0070efb70d5d1b3e9cae98105485f37d 219 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 82 185 1.6E-9 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDC59_RS07260 0070efb70d5d1b3e9cae98105485f37d 219 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 80 186 1.2E-12 T 29-03-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 CDC59_RS07260 0070efb70d5d1b3e9cae98105485f37d 219 Gene3D G3DSA:3.40.50.1000 1 31 0.036 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS07260 0070efb70d5d1b3e9cae98105485f37d 219 SUPERFAMILY SSF56784 5 216 2.98E-60 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS04265 69b5379af91fa08aba894cff1627c1e5 445 Gene3D G3DSA:3.90.1260.10 179 374 8.6E-59 T 29-03-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CDC59_RS04265 69b5379af91fa08aba894cff1627c1e5 445 TIGRFAM TIGR00032 argG: argininosuccinate synthase 13 420 2.8E-158 T 29-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CDC59_RS04265 69b5379af91fa08aba894cff1627c1e5 445 SUPERFAMILY SSF69864 190 440 3.92E-79 T 29-03-2018 CDC59_RS04265 69b5379af91fa08aba894cff1627c1e5 445 Pfam PF00764 Arginosuccinate synthase 16 406 5.5E-60 T 29-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CDC59_RS04265 69b5379af91fa08aba894cff1627c1e5 445 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 17 25 - T 29-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CDC59_RS04265 69b5379af91fa08aba894cff1627c1e5 445 Hamap MF_00581 Argininosuccinate synthase [argG]. 1 445 69.144 T 29-03-2018 IPR023437 Argininosuccinate synthase, type 2 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CDC59_RS04265 69b5379af91fa08aba894cff1627c1e5 445 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 129 140 - T 29-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CDC59_RS04265 69b5379af91fa08aba894cff1627c1e5 445 Gene3D G3DSA:3.40.50.620 2 178 4.1E-16 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDC59_RS04265 69b5379af91fa08aba894cff1627c1e5 445 Gene3D G3DSA:1.10.287.400 378 438 3.5E-30 T 29-03-2018 IPR024073 Argininosuccinate synthetase mutimerisation domain, C-terminal tail GO:0042803 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CDC59_RS04265 69b5379af91fa08aba894cff1627c1e5 445 SUPERFAMILY SSF52402 4 184 7.89E-31 T 29-03-2018 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Gene3D G3DSA:1.10.1200.10 4145 4297 0.69 T 29-03-2018 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 SUPERFAMILY SSF47336 518 591 8.77E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Gene3D G3DSA:3.40.50.980 2145 2231 1.9E-30 T 29-03-2018 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Gene3D G3DSA:1.10.1200.10 2673 2735 7.8E-24 T 29-03-2018 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Gene3D G3DSA:1.10.1200.10 3753 3816 3.3E-21 T 29-03-2018 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 SUPERFAMILY SSF47336 3741 3812 1.83E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 SUPERFAMILY SSF52777 1682 1859 2.0E-47 T 29-03-2018 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3773 3788 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 SUPERFAMILY SSF52777 2940 3180 6.23E-64 T 29-03-2018 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 SUPERFAMILY SSF52777 1873 2141 1.78E-58 T 29-03-2018 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Pfam PF00975 Thioesterase domain 4905 5131 4.5E-27 T 29-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Gene3D G3DSA:2.30.38.10 1394 1475 9.9E-23 T 29-03-2018 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Gene3D G3DSA:2.30.38.10 4619 4700 3.9E-26 T 29-03-2018 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Gene3D G3DSA:2.30.38.10 2469 2549 2.5E-23 T 29-03-2018 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Gene3D G3DSA:2.30.38.10 328 408 3.2E-22 T 29-03-2018 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Gene3D G3DSA:2.30.38.10 3546 3629 2.5E-24 T 29-03-2018 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 SUPERFAMILY SSF56801 2114 2232 7.2E-33 T 29-03-2018 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 SUPERFAMILY SSF56801 4270 4830 2.49E-161 T 29-03-2018 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 SUPERFAMILY SSF47336 2661 2734 1.57E-19 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4842 4857 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1110 1509 5.7E-129 T 29-03-2018 IPR010071 Amino acid adenylation domain CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 4330 4734 4.0E-132 T 29-03-2018 IPR010071 Amino acid adenylation domain CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 3247 3663 1.3E-139 T 29-03-2018 IPR010071 Amino acid adenylation domain CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2232 2583 2.0E-111 T 29-03-2018 IPR010071 Amino acid adenylation domain CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 51 442 6.5E-126 T 29-03-2018 IPR010071 Amino acid adenylation domain CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Pfam PF00501 AMP-binding enzyme 4309 4710 6.7E-102 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Pfam PF00501 AMP-binding enzyme 3226 3639 2.1E-104 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Pfam PF00501 AMP-binding enzyme 2232 2559 2.2E-76 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Pfam PF00501 AMP-binding enzyme 1089 1485 9.4E-98 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Pfam PF00501 AMP-binding enzyme 30 418 2.1E-97 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 SUPERFAMILY SSF47336 4811 4883 6.67E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Pfam PF13193 AMP-binding enzyme C-terminal domain 428 501 1.9E-12 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Pfam PF13193 AMP-binding enzyme C-terminal domain 1493 1568 5.3E-13 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Pfam PF13193 AMP-binding enzyme C-terminal domain 3647 3722 1.4E-12 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Pfam PF13193 AMP-binding enzyme C-terminal domain 2567 2642 2.4E-12 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Pfam PF13193 AMP-binding enzyme C-terminal domain 4718 4793 2.8E-16 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 ProSitePatterns PS00012 Phosphopantetheine attachment site. 550 565 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 SUPERFAMILY SSF52777 2756 2933 4.0E-43 T 29-03-2018 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Gene3D G3DSA:3.30.559.10 580 824 8.2E-42 T 29-03-2018 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Gene3D G3DSA:3.30.559.10 1661 1889 4.8E-43 T 29-03-2018 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Gene3D G3DSA:3.30.559.10 2736 2959 2.7E-42 T 29-03-2018 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Gene3D G3DSA:3.30.559.10 3817 4044 4.4E-50 T 29-03-2018 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Gene3D G3DSA:3.30.300.30 413 532 4.0E-38 T 29-03-2018 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Gene3D G3DSA:3.30.300.30 4705 4823 1.4E-41 T 29-03-2018 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Gene3D G3DSA:3.30.300.30 2554 2672 3.1E-41 T 29-03-2018 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Gene3D G3DSA:3.30.300.30 1480 1598 3.8E-41 T 29-03-2018 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Gene3D G3DSA:3.30.300.30 3634 3752 5.5E-43 T 29-03-2018 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Gene3D G3DSA:3.40.50.980 2317 2468 7.4E-34 T 29-03-2018 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Gene3D G3DSA:3.40.50.980 3380 3542 2.3E-40 T 29-03-2018 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Gene3D G3DSA:3.40.50.980 176 327 6.9E-34 T 29-03-2018 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Gene3D G3DSA:3.40.50.980 4459 4617 2.3E-30 T 29-03-2018 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Gene3D G3DSA:3.40.50.980 1235 1389 4.9E-33 T 29-03-2018 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Gene3D G3DSA:1.10.1200.10 533 579 9.4E-20 T 29-03-2018 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 SUPERFAMILY SSF56801 3181 3760 1.28E-166 T 29-03-2018 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2311 2322 - T 29-03-2018 IPR020845 AMP-binding, conserved site CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 SMART SM00823 Phosphopantetheine attachment site 4818 4887 3.4E-9 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 SMART SM00823 Phosphopantetheine attachment site 526 595 0.001 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 SMART SM00823 Phosphopantetheine attachment site 2669 2738 8.2E-5 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 SMART SM00823 Phosphopantetheine attachment site 3749 3818 3.0E-6 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 SMART SM00823 Phosphopantetheine attachment site 1593 1662 2.9E-6 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 ProSitePatterns PS00455 Putative AMP-binding domain signature. 170 181 - T 29-03-2018 IPR020845 AMP-binding, conserved site CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Pfam PF00668 Condensation domain 613 1070 8.2E-83 T 29-03-2018 IPR001242 Condensation domain CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Pfam PF00668 Condensation domain 3835 4288 2.2E-101 T 29-03-2018 IPR001242 Condensation domain CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Pfam PF00668 Condensation domain 2753 3203 2.9E-98 T 29-03-2018 IPR001242 Condensation domain CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Pfam PF00668 Condensation domain 1679 2135 1.4E-87 T 29-03-2018 IPR001242 Condensation domain CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Gene3D G3DSA:3.40.50.980 2232 2316 5.8E-23 T 29-03-2018 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Gene3D G3DSA:3.40.50.980 4300 4458 6.6E-50 T 29-03-2018 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Gene3D G3DSA:3.40.50.980 3218 3379 2.0E-48 T 29-03-2018 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Gene3D G3DSA:3.40.50.980 22 175 4.8E-49 T 29-03-2018 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Gene3D G3DSA:3.40.50.980 1081 1234 1.8E-48 T 29-03-2018 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 SUPERFAMILY SSF56801 1049 1600 1.44E-156 T 29-03-2018 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 SUPERFAMILY SSF53474 4885 5147 1.13E-50 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 ProSitePatterns PS00455 Putative AMP-binding domain signature. 3374 3385 - T 29-03-2018 IPR020845 AMP-binding, conserved site CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 SUPERFAMILY SSF52777 4029 4296 1.67E-65 T 29-03-2018 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 SMART SM01294 2670 2734 0.0085 T 29-03-2018 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 SUPERFAMILY SSF52777 3836 4023 1.67E-48 T 29-03-2018 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 SUPERFAMILY SSF52777 618 794 8.56E-47 T 29-03-2018 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 SUPERFAMILY SSF47336 1587 1658 3.66E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 SUPERFAMILY SSF56801 20 539 2.22E-155 T 29-03-2018 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1229 1240 - T 29-03-2018 IPR020845 AMP-binding, conserved site CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 ProSitePatterns PS00455 Putative AMP-binding domain signature. 4453 4464 - T 29-03-2018 IPR020845 AMP-binding, conserved site CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 SUPERFAMILY SSF52777 807 1076 2.11E-60 T 29-03-2018 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Gene3D G3DSA:1.10.1200.10 1599 1660 6.2E-24 T 29-03-2018 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Gene3D G3DSA:1.10.1200.10 4824 4889 2.5E-24 T 29-03-2018 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Gene3D G3DSA:3.40.50.1820 4890 5147 4.5E-18 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Pfam PF00550 Phosphopantetheine attachment site 2671 2734 8.0E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Pfam PF00550 Phosphopantetheine attachment site 1595 1658 7.6E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Pfam PF00550 Phosphopantetheine attachment site 3751 3812 1.1E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Pfam PF00550 Phosphopantetheine attachment site 4820 4883 5.1E-16 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 Pfam PF00550 Phosphopantetheine attachment site 529 591 2.4E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1617 1632 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 SUPERFAMILY SSF56801 2232 2681 1.31E-130 T 29-03-2018 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 SMART SM00824 Thioesterase 4908 5143 4.8E-5 T 29-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 CDC59_RS16600 26fdc6127bb6ef24a8500f67059b79a6 5147 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2693 2708 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CDC59_RS00285 29cd724c4ca0e0b6ee79c504caa92c2f 103 Pfam PF01355 High potential iron-sulfur protein 36 100 2.1E-24 T 29-03-2018 IPR000170 High potential iron-sulphur protein GO:0009055|GO:0019646 CDC59_RS00285 29cd724c4ca0e0b6ee79c504caa92c2f 103 Gene3D G3DSA:4.10.490.10 32 102 1.4E-26 T 29-03-2018 IPR000170 High potential iron-sulphur protein GO:0009055|GO:0019646 CDC59_RS00285 29cd724c4ca0e0b6ee79c504caa92c2f 103 SUPERFAMILY SSF57652 26 103 7.72E-27 T 29-03-2018 IPR000170 High potential iron-sulphur protein GO:0009055|GO:0019646 CDC59_RS03085 684f64f31d756aff3d195fd906766b2d 142 SUPERFAMILY SSF89447 2 129 1.09E-37 T 29-03-2018 CDC59_RS03085 684f64f31d756aff3d195fd906766b2d 142 Gene3D G3DSA:2.10.260.10 77 122 0.0031 T 29-03-2018 CDC59_RS03085 684f64f31d756aff3d195fd906766b2d 142 Gene3D G3DSA:2.10.260.10 3 46 4.6E-5 T 29-03-2018 CDC59_RS03085 684f64f31d756aff3d195fd906766b2d 142 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 142 49.493 T 29-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 CDC59_RS03085 684f64f31d756aff3d195fd906766b2d 142 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 121 5.0E-56 T 29-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 CDC59_RS03085 684f64f31d756aff3d195fd906766b2d 142 Pfam PF02381 MraZ protein, putative antitoxin-like 2 67 7.6E-15 T 29-03-2018 IPR020603 MraZ domain CDC59_RS03085 684f64f31d756aff3d195fd906766b2d 142 Pfam PF02381 MraZ protein, putative antitoxin-like 73 127 1.4E-12 T 29-03-2018 IPR020603 MraZ domain CDC59_RS03085 684f64f31d756aff3d195fd906766b2d 142 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 2 141 4.8E-33 T 29-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 CDC59_RS06590 8903aad0f83705aeacd2dab129b0c8bd 349 SUPERFAMILY SSF51735 148 312 1.34E-39 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS06590 8903aad0f83705aeacd2dab129b0c8bd 349 Gene3D G3DSA:3.40.50.20 284 342 1.6E-4 T 29-03-2018 CDC59_RS06590 8903aad0f83705aeacd2dab129b0c8bd 349 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 143 2.5E-25 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CDC59_RS06590 8903aad0f83705aeacd2dab129b0c8bd 349 Gene3D G3DSA:3.90.180.10 2 173 1.3E-43 T 29-03-2018 CDC59_RS06590 8903aad0f83705aeacd2dab129b0c8bd 349 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CDC59_RS06590 8903aad0f83705aeacd2dab129b0c8bd 349 Gene3D G3DSA:3.40.50.720 174 283 2.1E-21 T 29-03-2018 CDC59_RS06590 8903aad0f83705aeacd2dab129b0c8bd 349 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 178 205 - T 29-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 CDC59_RS06590 8903aad0f83705aeacd2dab129b0c8bd 349 Pfam PF00107 Zinc-binding dehydrogenase 185 306 1.4E-19 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CDC59_RS06590 8903aad0f83705aeacd2dab129b0c8bd 349 SMART SM00829 10 342 0.0024 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CDC59_RS06590 8903aad0f83705aeacd2dab129b0c8bd 349 SUPERFAMILY SSF50129 10 172 7.91E-48 T 29-03-2018 IPR011032 GroES-like CDC59_RS18520 137bca804f0cc6debc0483365dfdd2b8 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS18520 137bca804f0cc6debc0483365dfdd2b8 328 Pfam PF05598 Transposase domain (DUF772) 51 126 2.7E-23 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS23520 137bca804f0cc6debc0483365dfdd2b8 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS23520 137bca804f0cc6debc0483365dfdd2b8 328 Pfam PF05598 Transposase domain (DUF772) 51 126 2.7E-23 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS18565 137bca804f0cc6debc0483365dfdd2b8 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS18565 137bca804f0cc6debc0483365dfdd2b8 328 Pfam PF05598 Transposase domain (DUF772) 51 126 2.7E-23 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS16575 137bca804f0cc6debc0483365dfdd2b8 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS16575 137bca804f0cc6debc0483365dfdd2b8 328 Pfam PF05598 Transposase domain (DUF772) 51 126 2.7E-23 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS13095 137bca804f0cc6debc0483365dfdd2b8 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS13095 137bca804f0cc6debc0483365dfdd2b8 328 Pfam PF05598 Transposase domain (DUF772) 51 126 2.7E-23 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS02310 44946fb35053100e686c170cc89b733a 177 SUPERFAMILY SSF56053 83 177 3.93E-35 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS02310 44946fb35053100e686c170cc89b733a 177 SUPERFAMILY SSF56053 1 82 7.81E-25 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS02310 44946fb35053100e686c170cc89b733a 177 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 37.142 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CDC59_RS02310 44946fb35053100e686c170cc89b733a 177 PIRSF PIRSF002162 1 177 9.5E-45 T 29-03-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS02310 44946fb35053100e686c170cc89b733a 177 PRINTS PR00059 Ribosomal protein L6 signature 141 162 5.6E-32 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CDC59_RS02310 44946fb35053100e686c170cc89b733a 177 PRINTS PR00059 Ribosomal protein L6 signature 71 96 5.6E-32 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CDC59_RS02310 44946fb35053100e686c170cc89b733a 177 PRINTS PR00059 Ribosomal protein L6 signature 99 115 5.6E-32 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CDC59_RS02310 44946fb35053100e686c170cc89b733a 177 Gene3D G3DSA:3.90.930.12 83 177 3.6E-38 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS02310 44946fb35053100e686c170cc89b733a 177 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 2.9E-73 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CDC59_RS02310 44946fb35053100e686c170cc89b733a 177 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 154 162 - T 29-03-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS02310 44946fb35053100e686c170cc89b733a 177 Pfam PF00347 Ribosomal protein L6 90 164 7.9E-19 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS02310 44946fb35053100e686c170cc89b733a 177 Pfam PF00347 Ribosomal protein L6 12 82 3.6E-16 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS02310 44946fb35053100e686c170cc89b733a 177 Gene3D G3DSA:3.90.930.12 2 82 4.8E-26 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS17310 1a9af626c82b57bede1767403a14ff1c 745 Gene3D G3DSA:2.40.170.20 220 745 1.7E-64 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CDC59_RS17310 1a9af626c82b57bede1767403a14ff1c 745 Pfam PF07715 TonB-dependent Receptor Plug Domain 102 204 6.0E-19 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CDC59_RS17310 1a9af626c82b57bede1767403a14ff1c 745 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 728 745 - T 29-03-2018 IPR010917 TonB-dependent receptor, conserved site CDC59_RS17310 1a9af626c82b57bede1767403a14ff1c 745 Pfam PF00593 TonB dependent receptor 331 743 4.6E-36 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CDC59_RS17310 1a9af626c82b57bede1767403a14ff1c 745 Gene3D G3DSA:2.170.130.10 57 218 2.4E-25 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CDC59_RS17310 1a9af626c82b57bede1767403a14ff1c 745 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 104 745 1.7E-122 T 29-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 CDC59_RS17310 1a9af626c82b57bede1767403a14ff1c 745 SUPERFAMILY SSF56935 60 745 3.66E-112 T 29-03-2018 CDC59_RS10950 6e740a4636df284fd0b2fe94c2c72d74 165 SMART SM01103 6 89 5.8E-38 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CDC59_RS10950 6e740a4636df284fd0b2fe94c2c72d74 165 SUPERFAMILY SSF75471 5 92 1.18E-23 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CDC59_RS10950 6e740a4636df284fd0b2fe94c2c72d74 165 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 14 89 1.0E-37 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CDC59_RS10950 6e740a4636df284fd0b2fe94c2c72d74 165 Pfam PF01985 CRS1 / YhbY (CRM) domain 7 89 6.1E-15 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CDC59_RS10950 6e740a4636df284fd0b2fe94c2c72d74 165 Gene3D G3DSA:3.30.110.60 5 101 9.7E-18 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CDC59_RS00265 a6a67e91a3dad2d2c572141edafba264 300 SUPERFAMILY SSF109709 94 205 4.05E-18 T 29-03-2018 CDC59_RS00265 a6a67e91a3dad2d2c572141edafba264 300 Gene3D G3DSA:3.90.1530.10 2 101 2.4E-20 T 29-03-2018 CDC59_RS00265 a6a67e91a3dad2d2c572141edafba264 300 SUPERFAMILY SSF110849 8 105 9.42E-23 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CDC59_RS00265 a6a67e91a3dad2d2c572141edafba264 300 Pfam PF02195 ParB-like nuclease domain 12 102 9.1E-13 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CDC59_RS00265 a6a67e91a3dad2d2c572141edafba264 300 Pfam PF07506 RepB plasmid partitioning protein 103 270 3.0E-14 T 29-03-2018 IPR011111 RepB plasmid partition CDC59_RS00265 a6a67e91a3dad2d2c572141edafba264 300 SMART SM00470 11 102 3.8E-16 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CDC59_RS00265 a6a67e91a3dad2d2c572141edafba264 300 Gene3D G3DSA:1.10.10.730 102 148 1.4E-7 T 29-03-2018 CDC59_RS18345 c13c386884c6bdcb4f361eaa6e0415f5 222 Gene3D G3DSA:1.10.3480.10 1 180 4.6E-31 T 29-03-2018 IPR020945 DMSO/Nitrate reductase chaperone CDC59_RS18345 c13c386884c6bdcb4f361eaa6e0415f5 222 TIGRFAM TIGR00684 narJ: nitrate reductase molybdenum cofactor assembly chaperone 13 165 2.5E-29 T 29-03-2018 IPR003765 Nitrate reductase chaperone, NarJ GO:0051082|GO:0051131 CDC59_RS18345 c13c386884c6bdcb4f361eaa6e0415f5 222 Pfam PF02613 Nitrate reductase delta subunit 41 162 2.4E-10 T 29-03-2018 IPR020945 DMSO/Nitrate reductase chaperone CDC59_RS18345 c13c386884c6bdcb4f361eaa6e0415f5 222 SUPERFAMILY SSF89155 5 168 9.42E-33 T 29-03-2018 IPR020945 DMSO/Nitrate reductase chaperone CDC59_RS03770 10c9c16442e93915e3c948704467ffa9 407 Gene3D G3DSA:3.40.50.1100 51 180 5.4E-31 T 29-03-2018 CDC59_RS03770 10c9c16442e93915e3c948704467ffa9 407 TIGRFAM TIGR01747 diampropi_NH3ly: diaminopropionate ammonia-lyase family 24 390 4.6E-86 T 29-03-2018 IPR010081 Diaminopropionate ammonia-lyase GO:0008838|GO:0030170 CDC59_RS03770 10c9c16442e93915e3c948704467ffa9 407 SUPERFAMILY SSF53686 41 389 1.28E-65 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CDC59_RS03770 10c9c16442e93915e3c948704467ffa9 407 Gene3D G3DSA:3.40.50.1100 181 383 3.1E-32 T 29-03-2018 CDC59_RS03770 10c9c16442e93915e3c948704467ffa9 407 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 39 377 2.4E-73 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CDC59_RS09905 81d51b46acc3c80cf6f450e32f995d9f 461 Pfam PF13855 Leucine rich repeat 337 394 9.5E-10 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS09905 81d51b46acc3c80cf6f450e32f995d9f 461 Gene3D G3DSA:3.80.10.10 83 195 8.9E-7 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like CDC59_RS09905 81d51b46acc3c80cf6f450e32f995d9f 461 Gene3D G3DSA:3.80.10.10 315 391 5.0E-17 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like CDC59_RS09905 81d51b46acc3c80cf6f450e32f995d9f 461 Gene3D G3DSA:3.80.10.10 274 314 3.2E-7 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like CDC59_RS09905 81d51b46acc3c80cf6f450e32f995d9f 461 SUPERFAMILY SSF52047 141 376 4.45E-55 T 29-03-2018 CDC59_RS09905 81d51b46acc3c80cf6f450e32f995d9f 461 SMART SM00367 264 287 240.0 T 29-03-2018 IPR006553 Leucine-rich repeat, cysteine-containing subtype CDC59_RS09905 81d51b46acc3c80cf6f450e32f995d9f 461 SMART SM00367 191 215 80.0 T 29-03-2018 IPR006553 Leucine-rich repeat, cysteine-containing subtype CDC59_RS09905 81d51b46acc3c80cf6f450e32f995d9f 461 SMART SM00367 240 263 360.0 T 29-03-2018 IPR006553 Leucine-rich repeat, cysteine-containing subtype CDC59_RS09905 81d51b46acc3c80cf6f450e32f995d9f 461 SMART SM00367 216 239 110.0 T 29-03-2018 IPR006553 Leucine-rich repeat, cysteine-containing subtype CDC59_RS09905 81d51b46acc3c80cf6f450e32f995d9f 461 SMART SM00367 429 453 460.0 T 29-03-2018 IPR006553 Leucine-rich repeat, cysteine-containing subtype CDC59_RS09905 81d51b46acc3c80cf6f450e32f995d9f 461 SMART SM00367 381 405 450.0 T 29-03-2018 IPR006553 Leucine-rich repeat, cysteine-containing subtype CDC59_RS09905 81d51b46acc3c80cf6f450e32f995d9f 461 SMART SM00367 142 168 26.0 T 29-03-2018 IPR006553 Leucine-rich repeat, cysteine-containing subtype CDC59_RS09905 81d51b46acc3c80cf6f450e32f995d9f 461 SMART SM00368 191 214 68.0 T 29-03-2018 CDC59_RS09905 81d51b46acc3c80cf6f450e32f995d9f 461 SMART SM00368 263 286 25.0 T 29-03-2018 CDC59_RS09905 81d51b46acc3c80cf6f450e32f995d9f 461 SMART SM00368 215 238 1.7 T 29-03-2018 CDC59_RS09905 81d51b46acc3c80cf6f450e32f995d9f 461 SMART SM00368 335 364 2.0 T 29-03-2018 CDC59_RS09905 81d51b46acc3c80cf6f450e32f995d9f 461 SMART SM00368 429 458 16.0 T 29-03-2018 CDC59_RS09905 81d51b46acc3c80cf6f450e32f995d9f 461 SMART SM00368 121 147 270.0 T 29-03-2018 CDC59_RS09905 81d51b46acc3c80cf6f450e32f995d9f 461 SMART SM00368 405 428 56.0 T 29-03-2018 CDC59_RS09905 81d51b46acc3c80cf6f450e32f995d9f 461 SMART SM00368 239 262 0.5 T 29-03-2018 CDC59_RS09905 81d51b46acc3c80cf6f450e32f995d9f 461 SMART SM00368 381 404 1.7 T 29-03-2018 CDC59_RS09905 81d51b46acc3c80cf6f450e32f995d9f 461 SMART SM00368 287 316 7.2 T 29-03-2018 CDC59_RS09905 81d51b46acc3c80cf6f450e32f995d9f 461 Gene3D G3DSA:3.40.50.2000 392 461 7.7E-15 T 29-03-2018 CDC59_RS09905 81d51b46acc3c80cf6f450e32f995d9f 461 Gene3D G3DSA:3.40.50.2000 236 273 6.1E-15 T 29-03-2018 CDC59_RS09905 81d51b46acc3c80cf6f450e32f995d9f 461 Gene3D G3DSA:3.40.50.2000 196 235 2.8E-12 T 29-03-2018 CDC59_RS09905 81d51b46acc3c80cf6f450e32f995d9f 461 SUPERFAMILY SSF52058 337 459 7.99E-19 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like CDC59_RS09905 81d51b46acc3c80cf6f450e32f995d9f 461 Pfam PF13516 Leucine Rich repeat 405 427 1.4E-4 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS09905 81d51b46acc3c80cf6f450e32f995d9f 461 Pfam PF13516 Leucine Rich repeat 191 213 5.8E-5 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS09905 81d51b46acc3c80cf6f450e32f995d9f 461 Pfam PF13516 Leucine Rich repeat 262 285 0.38 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS09905 81d51b46acc3c80cf6f450e32f995d9f 461 Pfam PF13516 Leucine Rich repeat 215 237 1.5E-5 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS09905 81d51b46acc3c80cf6f450e32f995d9f 461 Pfam PF13516 Leucine Rich repeat 239 261 2.0E-7 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS09905 81d51b46acc3c80cf6f450e32f995d9f 461 Pfam PF13516 Leucine Rich repeat 287 308 5.3E-6 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS09905 81d51b46acc3c80cf6f450e32f995d9f 461 Pfam PF13516 Leucine Rich repeat 429 451 1.9E-5 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS16255 afbdcf6100e41c3e87cbff68e2d54c43 144 SUPERFAMILY SSF54593 4 135 4.4E-26 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CDC59_RS16255 afbdcf6100e41c3e87cbff68e2d54c43 144 Gene3D G3DSA:3.10.180.10 6 142 1.5E-19 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CDC59_RS16255 afbdcf6100e41c3e87cbff68e2d54c43 144 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 12 132 1.1E-6 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CDC59_RS10395 c6913b372ae07bf95103146ebd6e8efa 344 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 83 102 - T 29-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 CDC59_RS10395 c6913b372ae07bf95103146ebd6e8efa 344 Pfam PF01180 Dihydroorotate dehydrogenase 51 340 1.5E-85 T 29-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 CDC59_RS10395 c6913b372ae07bf95103146ebd6e8efa 344 PIRSF PIRSF000164 20 344 1.3E-92 T 29-03-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 CDC59_RS10395 c6913b372ae07bf95103146ebd6e8efa 344 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 5 342 51.199 T 29-03-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CDC59_RS10395 c6913b372ae07bf95103146ebd6e8efa 344 SUPERFAMILY SSF51395 6 340 1.28E-100 T 29-03-2018 CDC59_RS10395 c6913b372ae07bf95103146ebd6e8efa 344 Gene3D G3DSA:3.20.20.70 3 344 1.1E-82 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS10395 c6913b372ae07bf95103146ebd6e8efa 344 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 6 342 1.0E-127 T 29-03-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CDC59_RS21960 7ae95ea6e4d53e697002d4a06a245e5b 477 SMART SM00155 390 417 3.0E-7 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CDC59_RS21960 7ae95ea6e4d53e697002d4a06a245e5b 477 SMART SM00155 216 243 2.3E-5 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CDC59_RS21960 7ae95ea6e4d53e697002d4a06a245e5b 477 Pfam PF13091 PLD-like domain 135 276 1.4E-9 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CDC59_RS21960 7ae95ea6e4d53e697002d4a06a245e5b 477 Pfam PF13091 PLD-like domain 318 443 1.4E-28 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CDC59_RS21960 7ae95ea6e4d53e697002d4a06a245e5b 477 Gene3D G3DSA:3.30.870.10 316 466 6.0E-33 T 29-03-2018 CDC59_RS21960 7ae95ea6e4d53e697002d4a06a245e5b 477 Hamap MF_00190 Cardiolipin synthase A [clsA]. 1 477 45.75 T 29-03-2018 IPR030840 Cardiolipin synthase A GO:0008808|GO:0016780|GO:0032049 CDC59_RS21960 7ae95ea6e4d53e697002d4a06a245e5b 477 Gene3D G3DSA:3.30.870.10 111 283 1.4E-33 T 29-03-2018 CDC59_RS21960 7ae95ea6e4d53e697002d4a06a245e5b 477 SUPERFAMILY SSF56024 268 462 1.61E-49 T 29-03-2018 CDC59_RS21960 7ae95ea6e4d53e697002d4a06a245e5b 477 SUPERFAMILY SSF56024 93 306 1.18E-52 T 29-03-2018 CDC59_RS21960 7ae95ea6e4d53e697002d4a06a245e5b 477 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 15 477 4.5E-109 T 29-03-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 CDC59_RS15740 7c1277ea29172725394ab0f5821e4fac 240 SUPERFAMILY SSF52172 1 122 3.13E-36 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS15740 7c1277ea29172725394ab0f5821e4fac 240 SMART SM00448 2 114 4.9E-33 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS15740 7c1277ea29172725394ab0f5821e4fac 240 Pfam PF02954 Bacterial regulatory protein, Fis family 188 227 4.3E-6 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CDC59_RS15740 7c1277ea29172725394ab0f5821e4fac 240 Pfam PF00072 Response regulator receiver domain 4 115 3.0E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS15740 7c1277ea29172725394ab0f5821e4fac 240 Gene3D G3DSA:3.40.50.2300 1 131 3.0E-31 T 29-03-2018 CDC59_RS15740 7c1277ea29172725394ab0f5821e4fac 240 SUPERFAMILY SSF46689 173 229 3.14E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS15740 7c1277ea29172725394ab0f5821e4fac 240 Gene3D G3DSA:1.10.10.60 178 234 5.0E-13 T 29-03-2018 CDC59_RS03525 22dc8f91a5485cb09c36752605977fe8 201 SUPERFAMILY SSF52038 102 194 1.28E-22 T 29-03-2018 IPR000468 Barstar (barnase inhibitor) CDC59_RS03525 22dc8f91a5485cb09c36752605977fe8 201 Gene3D G3DSA:3.30.370.10 102 198 9.9E-21 T 29-03-2018 IPR000468 Barstar (barnase inhibitor) CDC59_RS03525 22dc8f91a5485cb09c36752605977fe8 201 Pfam PF01337 Barstar (barnase inhibitor) 106 190 1.2E-26 T 29-03-2018 IPR000468 Barstar (barnase inhibitor) CDC59_RS18385 18e20449ead86ccb37bffd7f7b7f6ea7 678 SUPERFAMILY SSF51126 203 291 1.62E-10 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CDC59_RS18385 18e20449ead86ccb37bffd7f7b7f6ea7 678 SUPERFAMILY SSF51126 422 495 1.62E-10 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CDC59_RS18385 18e20449ead86ccb37bffd7f7b7f6ea7 678 Gene3D G3DSA:2.160.20.10 127 612 5.4E-14 T 29-03-2018 IPR012334 Pectin lyase fold CDC59_RS07995 9712abbe38accdf0c329a928622a0db3 87 Pfam PF01197 Ribosomal protein L31 1 79 5.4E-30 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS07995 9712abbe38accdf0c329a928622a0db3 87 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 80 1.7E-21 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS07995 9712abbe38accdf0c329a928622a0db3 87 SUPERFAMILY SSF143800 1 79 1.22E-22 T 29-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS07995 9712abbe38accdf0c329a928622a0db3 87 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 1 81 26.471 T 29-03-2018 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS07995 9712abbe38accdf0c329a928622a0db3 87 PRINTS PR01249 Ribosomal protein L31 signature 2 19 9.6E-18 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS07995 9712abbe38accdf0c329a928622a0db3 87 PRINTS PR01249 Ribosomal protein L31 signature 45 60 9.6E-18 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS07995 9712abbe38accdf0c329a928622a0db3 87 PRINTS PR01249 Ribosomal protein L31 signature 60 78 9.6E-18 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS07995 9712abbe38accdf0c329a928622a0db3 87 ProSitePatterns PS01143 Ribosomal protein L31 signature. 49 70 - T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS19275 f07c29be340a87fc517e4c1983139e51 158 SMART SM00347 23 126 5.7E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS19275 f07c29be340a87fc517e4c1983139e51 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 102 3.4E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS19275 f07c29be340a87fc517e4c1983139e51 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 50 66 3.4E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS19275 f07c29be340a87fc517e4c1983139e51 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 67 82 3.4E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS19275 f07c29be340a87fc517e4c1983139e51 158 Pfam PF12802 MarR family 33 89 1.9E-13 T 29-03-2018 CDC59_RS19275 f07c29be340a87fc517e4c1983139e51 158 Gene3D G3DSA:1.10.10.10 2 157 1.8E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS19275 f07c29be340a87fc517e4c1983139e51 158 SUPERFAMILY SSF46785 9 140 7.67E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS08735 4cd5f25c752aa41ac7ce39bbd45243ed 332 SUPERFAMILY SSF53448 2 255 1.04E-35 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDC59_RS08735 4cd5f25c752aa41ac7ce39bbd45243ed 332 Pfam PF00535 Glycosyl transferase family 2 7 168 3.3E-28 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CDC59_RS08735 4cd5f25c752aa41ac7ce39bbd45243ed 332 Gene3D G3DSA:3.90.550.10 2 252 3.4E-28 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDC59_RS20360 7b736b4e0c1019afa9969eaf40855a06 399 Gene3D G3DSA:3.90.1150.10 291 399 5.3E-27 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS20360 7b736b4e0c1019afa9969eaf40855a06 399 SUPERFAMILY SSF53383 7 397 2.5E-120 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS20360 7b736b4e0c1019afa9969eaf40855a06 399 TIGRFAM TIGR01822 2am3keto_CoA: glycine C-acetyltransferase 7 399 1.6E-214 T 29-03-2018 IPR011282 2-amino-3-ketobutyrate coenzyme A ligase GO:0006567|GO:0008890 KEGG: 00260+2.3.1.29|Reactome: R-HSA-8849175 CDC59_RS20360 7b736b4e0c1019afa9969eaf40855a06 399 Gene3D G3DSA:3.40.640.10 52 290 1.1E-54 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDC59_RS20360 7b736b4e0c1019afa9969eaf40855a06 399 Hamap MF_00985 2-amino-3-ketobutyrate coenzyme A ligase [kbl]. 4 397 52.042 T 29-03-2018 IPR011282 2-amino-3-ketobutyrate coenzyme A ligase GO:0006567|GO:0008890 KEGG: 00260+2.3.1.29|Reactome: R-HSA-8849175 CDC59_RS20360 7b736b4e0c1019afa9969eaf40855a06 399 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 243 252 - T 29-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 CDC59_RS20360 7b736b4e0c1019afa9969eaf40855a06 399 Pfam PF00155 Aminotransferase class I and II 45 388 5.8E-68 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CDC59_RS10560 bec62dcf9397cc6b91cf50b5f6c58123 362 Gene3D G3DSA:3.30.1490.100 243 355 1.8E-18 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CDC59_RS10560 bec62dcf9397cc6b91cf50b5f6c58123 362 Hamap MF_01113 DNA polymerase IV [dinB]. 6 353 37.114 T 29-03-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 CDC59_RS10560 bec62dcf9397cc6b91cf50b5f6c58123 362 Gene3D G3DSA:3.30.70.270 119 176 1.4E-21 T 29-03-2018 CDC59_RS10560 bec62dcf9397cc6b91cf50b5f6c58123 362 Gene3D G3DSA:3.30.70.270 46 118 5.9E-29 T 29-03-2018 CDC59_RS10560 bec62dcf9397cc6b91cf50b5f6c58123 362 Pfam PF00817 impB/mucB/samB family 13 159 1.1E-52 T 29-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CDC59_RS10560 bec62dcf9397cc6b91cf50b5f6c58123 362 Gene3D G3DSA:1.10.150.20 177 242 3.3E-23 T 29-03-2018 CDC59_RS10560 bec62dcf9397cc6b91cf50b5f6c58123 362 SUPERFAMILY SSF100879 246 350 2.35E-22 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CDC59_RS10560 bec62dcf9397cc6b91cf50b5f6c58123 362 Pfam PF11799 impB/mucB/samB family C-terminal domain 238 346 1.3E-8 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CDC59_RS10560 bec62dcf9397cc6b91cf50b5f6c58123 362 SUPERFAMILY SSF56672 4 239 1.07E-92 T 29-03-2018 CDC59_RS04015 087a473e0aabbe423dcfe1c29a222e27 537 PRINTS PR00723 Subtilisin serine protease family (S8) signature 165 184 6.8E-8 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CDC59_RS04015 087a473e0aabbe423dcfe1c29a222e27 537 PRINTS PR00723 Subtilisin serine protease family (S8) signature 235 248 6.8E-8 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CDC59_RS04015 087a473e0aabbe423dcfe1c29a222e27 537 PRINTS PR00723 Subtilisin serine protease family (S8) signature 423 439 6.8E-8 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CDC59_RS04015 087a473e0aabbe423dcfe1c29a222e27 537 Gene3D G3DSA:3.40.50.200 102 491 1.0E-55 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CDC59_RS04015 087a473e0aabbe423dcfe1c29a222e27 537 Pfam PF00082 Subtilase family 167 462 1.0E-27 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CDC59_RS04015 087a473e0aabbe423dcfe1c29a222e27 537 TIGRFAM TIGR03867 MprA_tail: MprA protease C-terminal rhombosortase-interaction domain 509 533 2.2E-7 T 29-03-2018 IPR021206 MprA protease C-terminal rhombosortase-interaction domain CDC59_RS04015 087a473e0aabbe423dcfe1c29a222e27 537 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 424 434 - T 29-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CDC59_RS04015 087a473e0aabbe423dcfe1c29a222e27 537 SUPERFAMILY SSF52743 239 490 3.01E-52 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CDC59_RS04015 087a473e0aabbe423dcfe1c29a222e27 537 SUPERFAMILY SSF52743 130 205 3.01E-52 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CDC59_RS23010 d45c023a25b1f2512fa7e027cebb3aa5 493 Gene3D G3DSA:3.40.605.10 10 280 4.5E-98 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CDC59_RS23010 d45c023a25b1f2512fa7e027cebb3aa5 493 SUPERFAMILY SSF53720 10 489 4.06E-168 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CDC59_RS23010 d45c023a25b1f2512fa7e027cebb3aa5 493 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 262 269 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CDC59_RS23010 d45c023a25b1f2512fa7e027cebb3aa5 493 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 290 301 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CDC59_RS23010 d45c023a25b1f2512fa7e027cebb3aa5 493 Gene3D G3DSA:3.40.309.10 281 473 3.9E-73 T 29-03-2018 CDC59_RS23010 d45c023a25b1f2512fa7e027cebb3aa5 493 Pfam PF00171 Aldehyde dehydrogenase family 26 485 1.2E-165 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CDC59_RS21720 1b386bac09daee5c2184f6593c81e05b 219 Pfam PF00072 Response regulator receiver domain 2 111 2.2E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS21720 1b386bac09daee5c2184f6593c81e05b 219 Gene3D G3DSA:3.40.50.2300 1 122 3.7E-35 T 29-03-2018 CDC59_RS21720 1b386bac09daee5c2184f6593c81e05b 219 SUPERFAMILY SSF46894 128 217 1.81E-24 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CDC59_RS21720 1b386bac09daee5c2184f6593c81e05b 219 Gene3D G3DSA:1.10.10.10 123 219 5.7E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS21720 1b386bac09daee5c2184f6593c81e05b 219 SMART SM00862 141 217 4.6E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDC59_RS21720 1b386bac09daee5c2184f6593c81e05b 219 SMART SM00448 1 110 1.4E-38 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS21720 1b386bac09daee5c2184f6593c81e05b 219 Pfam PF00486 Transcriptional regulatory protein, C terminal 141 217 2.3E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDC59_RS21720 1b386bac09daee5c2184f6593c81e05b 219 SUPERFAMILY SSF52172 2 120 2.85E-39 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS03400 1c6436497e7aa8115491d6c0ee3b506e 311 Gene3D G3DSA:3.40.1190.20 1 307 1.4E-49 T 29-03-2018 IPR029056 Ribokinase-like CDC59_RS03400 1c6436497e7aa8115491d6c0ee3b506e 311 Pfam PF00294 pfkB family carbohydrate kinase 25 290 3.6E-42 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB CDC59_RS03400 1c6436497e7aa8115491d6c0ee3b506e 311 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 47 71 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CDC59_RS03400 1c6436497e7aa8115491d6c0ee3b506e 311 SUPERFAMILY SSF53613 4 291 1.34E-64 T 29-03-2018 IPR029056 Ribokinase-like CDC59_RS11690 4c5ca0dfb56c9699f0e7dd47c10f9dc3 287 ProSitePatterns PS00211 ABC transporters family signature. 186 200 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS11690 4c5ca0dfb56c9699f0e7dd47c10f9dc3 287 TIGRFAM TIGR03411 urea_trans_UrtD: urea ABC transporter, ATP-binding protein UrtD 39 287 5.4E-105 T 29-03-2018 IPR017781 ABC transporter, urea, ATP-binding protein, UrtD CDC59_RS11690 4c5ca0dfb56c9699f0e7dd47c10f9dc3 287 SUPERFAMILY SSF52540 38 284 4.88E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS11690 4c5ca0dfb56c9699f0e7dd47c10f9dc3 287 Pfam PF00005 ABC transporter 55 214 6.8E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS11690 4c5ca0dfb56c9699f0e7dd47c10f9dc3 287 Gene3D G3DSA:3.40.50.300 30 286 5.3E-50 T 29-03-2018 CDC59_RS11690 4c5ca0dfb56c9699f0e7dd47c10f9dc3 287 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 265 286 7.7E-8 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CDC59_RS05000 f36ddda2169296fd80232714c33b0da7 127 SUPERFAMILY SSF161084 3 122 3.27E-28 T 29-03-2018 CDC59_RS05000 f36ddda2169296fd80232714c33b0da7 127 Pfam PF01124 MAPEG family 3 124 1.9E-27 T 29-03-2018 IPR001129 Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein CDC59_RS05000 f36ddda2169296fd80232714c33b0da7 127 Gene3D G3DSA:1.20.120.550 1 126 3.1E-24 T 29-03-2018 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain CDC59_RS18640 cbf6efb84e0e2ee0347917d95eb9a778 510 Gene3D G3DSA:3.40.630.10 58 259 7.2E-40 T 29-03-2018 CDC59_RS18640 cbf6efb84e0e2ee0347917d95eb9a778 510 Pfam PF07687 Peptidase dimerisation domain 253 402 8.6E-19 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CDC59_RS18640 cbf6efb84e0e2ee0347917d95eb9a778 510 SUPERFAMILY SSF55031 256 301 2.09E-9 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CDC59_RS18640 cbf6efb84e0e2ee0347917d95eb9a778 510 SUPERFAMILY SSF55031 350 399 2.09E-9 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CDC59_RS18640 cbf6efb84e0e2ee0347917d95eb9a778 510 SUPERFAMILY SSF53187 417 506 1.91E-54 T 29-03-2018 CDC59_RS18640 cbf6efb84e0e2ee0347917d95eb9a778 510 SUPERFAMILY SSF53187 62 240 1.91E-54 T 29-03-2018 CDC59_RS18640 cbf6efb84e0e2ee0347917d95eb9a778 510 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 129 138 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CDC59_RS18640 cbf6efb84e0e2ee0347917d95eb9a778 510 Pfam PF01546 Peptidase family M20/M25/M40 130 503 1.5E-38 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CDC59_RS18640 cbf6efb84e0e2ee0347917d95eb9a778 510 Gene3D G3DSA:3.30.70.360 260 408 1.6E-21 T 29-03-2018 CDC59_RS18640 cbf6efb84e0e2ee0347917d95eb9a778 510 PIRSF PIRSF036696 69 293 2.1E-28 T 29-03-2018 CDC59_RS18640 cbf6efb84e0e2ee0347917d95eb9a778 510 PIRSF PIRSF036696 328 510 4.0E-9 T 29-03-2018 CDC59_RS06875 0e2f12d72674ec83721e9faae71db4bb 933 Gene3D G3DSA:3.40.1360.10 214 346 9.6E-13 T 29-03-2018 CDC59_RS06875 0e2f12d72674ec83721e9faae71db4bb 933 SUPERFAMILY SSF57783 10 104 5.44E-15 T 29-03-2018 CDC59_RS06875 0e2f12d72674ec83721e9faae71db4bb 933 Pfam PF13362 Toprim domain 228 334 3.4E-24 T 29-03-2018 IPR006171 TOPRIM domain CDC59_RS06875 0e2f12d72674ec83721e9faae71db4bb 933 Gene3D G3DSA:3.90.580.10 8 106 2.6E-14 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CDC59_RS09015 244c7212da8d7215f9cc7d4dd1ba7bae 615 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS09015 244c7212da8d7215f9cc7d4dd1ba7bae 615 ProSitePatterns PS00211 ABC transporters family signature. 459 473 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS09015 244c7212da8d7215f9cc7d4dd1ba7bae 615 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 242 271 3.7E-8 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CDC59_RS09015 244c7212da8d7215f9cc7d4dd1ba7bae 615 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 538 572 4.7E-9 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CDC59_RS09015 244c7212da8d7215f9cc7d4dd1ba7bae 615 SUPERFAMILY SSF52540 6 262 5.88E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS09015 244c7212da8d7215f9cc7d4dd1ba7bae 615 SMART SM00382 35 240 6.0E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS09015 244c7212da8d7215f9cc7d4dd1ba7bae 615 SMART SM00382 344 544 1.8E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS09015 244c7212da8d7215f9cc7d4dd1ba7bae 615 Pfam PF00005 ABC transporter 336 485 1.9E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS09015 244c7212da8d7215f9cc7d4dd1ba7bae 615 Pfam PF00005 ABC transporter 27 190 1.8E-24 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS09015 244c7212da8d7215f9cc7d4dd1ba7bae 615 Gene3D G3DSA:3.40.50.300 4 276 1.9E-65 T 29-03-2018 CDC59_RS09015 244c7212da8d7215f9cc7d4dd1ba7bae 615 Gene3D G3DSA:3.40.50.300 305 589 4.3E-70 T 29-03-2018 CDC59_RS09015 244c7212da8d7215f9cc7d4dd1ba7bae 615 SUPERFAMILY SSF52540 309 558 2.02E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS00380 c02ada05f6175f9d10761e4fd567b8ad 262 Pfam PF09339 IclR helix-turn-helix domain 15 66 2.5E-16 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CDC59_RS00380 c02ada05f6175f9d10761e4fd567b8ad 262 Gene3D G3DSA:3.30.450.40 79 261 3.9E-49 T 29-03-2018 IPR029016 GAF domain-like CDC59_RS00380 c02ada05f6175f9d10761e4fd567b8ad 262 SMART SM00346 13 103 1.6E-27 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CDC59_RS00380 c02ada05f6175f9d10761e4fd567b8ad 262 SUPERFAMILY SSF46785 14 85 4.92E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS00380 c02ada05f6175f9d10761e4fd567b8ad 262 SUPERFAMILY SSF55781 80 256 6.87E-49 T 29-03-2018 IPR029016 GAF domain-like CDC59_RS00380 c02ada05f6175f9d10761e4fd567b8ad 262 Pfam PF01614 Bacterial transcriptional regulator 133 256 2.8E-29 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CDC59_RS00380 c02ada05f6175f9d10761e4fd567b8ad 262 Gene3D G3DSA:1.10.10.10 13 76 2.8E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS19635 8192102c9002256d289b056ccbab9864 170 PIRSF PIRSF028301 2 170 9.0E-67 T 29-03-2018 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 CDC59_RS19635 8192102c9002256d289b056ccbab9864 170 Pfam PF05591 Type VI secretion system, VipA, VC_A0107 or Hcp2 12 163 9.2E-61 T 29-03-2018 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 CDC59_RS19635 8192102c9002256d289b056ccbab9864 170 TIGRFAM TIGR03358 VI_chp_5: type VI secretion protein, VC_A0107 family 8 163 4.1E-59 T 29-03-2018 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 CDC59_RS13985 61284dbb5f5d234d3b29fdaf6d3b11f5 1348 Pfam PF02913 FAD linked oxidases, C-terminal domain 727 815 2.3E-16 T 29-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CDC59_RS13985 61284dbb5f5d234d3b29fdaf6d3b11f5 1348 Pfam PF02913 FAD linked oxidases, C-terminal domain 461 575 3.7E-4 T 29-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CDC59_RS13985 61284dbb5f5d234d3b29fdaf6d3b11f5 1348 Pfam PF13183 4Fe-4S dicluster domain 860 938 6.2E-7 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CDC59_RS13985 61284dbb5f5d234d3b29fdaf6d3b11f5 1348 Pfam PF02754 Cysteine-rich domain 1194 1299 0.015 T 29-03-2018 IPR004017 Cysteine-rich domain CDC59_RS13985 61284dbb5f5d234d3b29fdaf6d3b11f5 1348 Pfam PF02754 Cysteine-rich domain 1069 1158 9.6E-7 T 29-03-2018 IPR004017 Cysteine-rich domain CDC59_RS13985 61284dbb5f5d234d3b29fdaf6d3b11f5 1348 Gene3D G3DSA:1.10.1060.10 802 960 3.5E-13 T 29-03-2018 CDC59_RS13985 61284dbb5f5d234d3b29fdaf6d3b11f5 1348 Pfam PF11880 Domain of unknown function (DUF3400) 1304 1348 1.0E-23 T 29-03-2018 IPR021817 Protein of unknown function DUF3400 CDC59_RS13985 61284dbb5f5d234d3b29fdaf6d3b11f5 1348 Gene3D G3DSA:3.30.465.10 254 446 1.0E-20 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CDC59_RS13985 61284dbb5f5d234d3b29fdaf6d3b11f5 1348 SUPERFAMILY SSF55103 456 581 4.91E-14 T 29-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CDC59_RS13985 61284dbb5f5d234d3b29fdaf6d3b11f5 1348 SUPERFAMILY SSF55103 711 820 2.13E-26 T 29-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CDC59_RS13985 61284dbb5f5d234d3b29fdaf6d3b11f5 1348 Pfam PF01565 FAD binding domain 193 338 3.3E-24 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CDC59_RS13985 61284dbb5f5d234d3b29fdaf6d3b11f5 1348 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 924 935 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CDC59_RS13985 61284dbb5f5d234d3b29fdaf6d3b11f5 1348 SUPERFAMILY SSF56176 157 424 4.44E-55 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CDC59_RS13985 61284dbb5f5d234d3b29fdaf6d3b11f5 1348 SUPERFAMILY SSF46548 832 955 4.19E-13 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CDC59_RS13985 61284dbb5f5d234d3b29fdaf6d3b11f5 1348 Pfam PF12447 Protein of unknown function (DUF3683) 19 143 9.4E-54 T 29-03-2018 IPR022153 Protein of unknown function DUF3683 CDC59_RS13985 61284dbb5f5d234d3b29fdaf6d3b11f5 1348 Gene3D G3DSA:3.30.43.10 128 245 3.4E-14 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CDC59_RS02250 522839cda6f11e21fb79258f9db1bce7 276 Gene3D G3DSA:4.10.950.10 198 274 7.1E-36 T 29-03-2018 IPR014726 Ribosomal protein L2, domain 3 CDC59_RS02250 522839cda6f11e21fb79258f9db1bce7 276 SMART SM01383 42 119 6.3E-40 T 29-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS02250 522839cda6f11e21fb79258f9db1bce7 276 PIRSF PIRSF002158 13 276 8.0E-98 T 29-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS02250 522839cda6f11e21fb79258f9db1bce7 276 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 274 45.7 T 29-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 CDC59_RS02250 522839cda6f11e21fb79258f9db1bce7 276 SMART SM01382 125 253 9.0E-89 T 29-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 CDC59_RS02250 522839cda6f11e21fb79258f9db1bce7 276 Gene3D G3DSA:2.40.50.140 1 115 1.6E-41 T 29-03-2018 CDC59_RS02250 522839cda6f11e21fb79258f9db1bce7 276 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 117 1.0E-30 T 29-03-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS02250 522839cda6f11e21fb79258f9db1bce7 276 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 127 251 2.2E-55 T 29-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 CDC59_RS02250 522839cda6f11e21fb79258f9db1bce7 276 SUPERFAMILY SSF50249 3 126 5.14E-47 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDC59_RS02250 522839cda6f11e21fb79258f9db1bce7 276 ProSitePatterns PS00467 Ribosomal protein L2 signature. 219 230 - T 29-03-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS02250 522839cda6f11e21fb79258f9db1bce7 276 Gene3D G3DSA:2.30.30.30 120 196 5.7E-31 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 CDC59_RS02250 522839cda6f11e21fb79258f9db1bce7 276 SUPERFAMILY SSF50104 128 273 6.02E-60 T 29-03-2018 IPR008991 Translation protein SH3-like domain CDC59_RS02250 522839cda6f11e21fb79258f9db1bce7 276 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 4 274 1.7E-125 T 29-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 CDC59_RS08775 8ab773b0aeadeda6f11edeffe0f25cd9 206 SMART SM00986 37 197 2.0E-27 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CDC59_RS08775 8ab773b0aeadeda6f11edeffe0f25cd9 206 SUPERFAMILY SSF52141 16 199 2.13E-51 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CDC59_RS08775 8ab773b0aeadeda6f11edeffe0f25cd9 206 Pfam PF03167 Uracil DNA glycosylase superfamily 41 193 2.2E-24 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CDC59_RS08775 8ab773b0aeadeda6f11edeffe0f25cd9 206 Gene3D G3DSA:3.40.470.10 7 206 9.5E-46 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CDC59_RS08775 8ab773b0aeadeda6f11edeffe0f25cd9 206 SMART SM00987 37 197 2.0E-27 T 29-03-2018 CDC59_RS07020 8281cd7d3f581fc1de2241130813213c 123 SMART SM00418 10 88 7.2E-19 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CDC59_RS07020 8281cd7d3f581fc1de2241130813213c 123 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 59 74 5.2E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CDC59_RS07020 8281cd7d3f581fc1de2241130813213c 123 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 44 59 5.2E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CDC59_RS07020 8281cd7d3f581fc1de2241130813213c 123 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 12 27 5.2E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CDC59_RS07020 8281cd7d3f581fc1de2241130813213c 123 SUPERFAMILY SSF46785 5 106 1.72E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS07020 8281cd7d3f581fc1de2241130813213c 123 Pfam PF12840 Helix-turn-helix domain 10 64 2.4E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS07020 8281cd7d3f581fc1de2241130813213c 123 Gene3D G3DSA:3.30.530.20 81 123 0.0016 T 29-03-2018 IPR023393 START-like domain CDC59_RS07020 8281cd7d3f581fc1de2241130813213c 123 Gene3D G3DSA:1.10.10.10 3 80 1.2E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS02775 4b1dc0be27ddb94777ff2dc0ff796838 75 Pfam PF09360 Iron-binding zinc finger CDGSH type 12 57 1.3E-18 T 29-03-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 CDC59_RS02775 4b1dc0be27ddb94777ff2dc0ff796838 75 SMART SM00704 26 62 1.9E-10 T 29-03-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 CDC59_RS04135 81b66ac412626fb7df3abc40a1e8d0b0 214 Pfam PF01712 Deoxynucleoside kinase 9 200 3.1E-29 T 29-03-2018 IPR031314 Deoxynucleoside kinase domain CDC59_RS04135 81b66ac412626fb7df3abc40a1e8d0b0 214 Gene3D G3DSA:3.40.50.300 3 205 7.0E-30 T 29-03-2018 CDC59_RS04135 81b66ac412626fb7df3abc40a1e8d0b0 214 SUPERFAMILY SSF52540 6 204 4.38E-36 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS04135 81b66ac412626fb7df3abc40a1e8d0b0 214 PIRSF PIRSF000705 1 208 8.5E-51 T 29-03-2018 IPR002624 Deoxynucleoside kinase GO:0005524|GO:0006139|GO:0019206 CDC59_RS21630 e2d48e320640c24a5025cf969ca0c50f 298 TIGRFAM TIGR03298 argP: transcriptional regulator, ArgP family 2 294 3.1E-120 T 29-03-2018 IPR017685 HTH-type transcriptional regulator ArgP CDC59_RS21630 e2d48e320640c24a5025cf969ca0c50f 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 62 8.5E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS21630 e2d48e320640c24a5025cf969ca0c50f 298 Pfam PF03466 LysR substrate binding domain 97 276 1.1E-16 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS21630 e2d48e320640c24a5025cf969ca0c50f 298 SUPERFAMILY SSF46785 1 109 5.3E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS21630 e2d48e320640c24a5025cf969ca0c50f 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.0E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS21630 e2d48e320640c24a5025cf969ca0c50f 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.0E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS21630 e2d48e320640c24a5025cf969ca0c50f 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.0E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS21630 e2d48e320640c24a5025cf969ca0c50f 298 Gene3D G3DSA:3.40.190.10 94 195 2.3E-40 T 29-03-2018 CDC59_RS21630 e2d48e320640c24a5025cf969ca0c50f 298 Gene3D G3DSA:1.10.10.10 1 88 1.9E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS21630 e2d48e320640c24a5025cf969ca0c50f 298 SUPERFAMILY SSF53850 95 278 4.34E-22 T 29-03-2018 CDC59_RS00125 bb7870e4080366e8f52a6f8f4c75826d 210 SMART SM00448 5 118 3.1E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS00125 bb7870e4080366e8f52a6f8f4c75826d 210 SMART SM00421 146 203 4.2E-21 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS00125 bb7870e4080366e8f52a6f8f4c75826d 210 Gene3D G3DSA:1.10.10.10 130 208 3.5E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS00125 bb7870e4080366e8f52a6f8f4c75826d 210 Pfam PF00072 Response regulator receiver domain 8 118 2.4E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS00125 bb7870e4080366e8f52a6f8f4c75826d 210 SUPERFAMILY SSF46894 131 207 5.44E-21 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CDC59_RS00125 bb7870e4080366e8f52a6f8f4c75826d 210 ProSitePatterns PS00622 LuxR-type HTH domain signature. 163 190 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS00125 bb7870e4080366e8f52a6f8f4c75826d 210 SUPERFAMILY SSF52172 4 131 1.25E-32 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS00125 bb7870e4080366e8f52a6f8f4c75826d 210 Gene3D G3DSA:3.40.50.2300 4 129 1.5E-34 T 29-03-2018 CDC59_RS00125 bb7870e4080366e8f52a6f8f4c75826d 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 2.9E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS00125 bb7870e4080366e8f52a6f8f4c75826d 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 2.9E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS00125 bb7870e4080366e8f52a6f8f4c75826d 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 2.9E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS00125 bb7870e4080366e8f52a6f8f4c75826d 210 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 203 1.9E-17 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS01895 045ddda1f54739844408b5fcb008d12d 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 171 1.6E-7 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS01895 045ddda1f54739844408b5fcb008d12d 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 187 199 1.6E-7 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS01895 045ddda1f54739844408b5fcb008d12d 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 187 1.6E-7 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS01895 045ddda1f54739844408b5fcb008d12d 222 SMART SM00421 154 211 6.0E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS01895 045ddda1f54739844408b5fcb008d12d 222 Pfam PF00072 Response regulator receiver domain 8 121 7.4E-17 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS01895 045ddda1f54739844408b5fcb008d12d 222 Gene3D G3DSA:1.10.10.10 132 221 1.4E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS01895 045ddda1f54739844408b5fcb008d12d 222 SMART SM00448 5 121 1.0E-5 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS01895 045ddda1f54739844408b5fcb008d12d 222 SUPERFAMILY SSF52172 5 135 3.7E-20 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS01895 045ddda1f54739844408b5fcb008d12d 222 Pfam PF00196 Bacterial regulatory proteins, luxR family 156 210 9.5E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS01895 045ddda1f54739844408b5fcb008d12d 222 Gene3D G3DSA:3.40.50.2300 4 131 7.0E-22 T 29-03-2018 CDC59_RS01895 045ddda1f54739844408b5fcb008d12d 222 SUPERFAMILY SSF46894 149 217 1.63E-15 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CDC59_RS23720 908dc0a54617a8315d81ab3095f1b22c 297 SUPERFAMILY SSF103481 185 282 3.27E-12 T 29-03-2018 CDC59_RS23720 908dc0a54617a8315d81ab3095f1b22c 297 SUPERFAMILY SSF103481 35 139 3.01E-12 T 29-03-2018 CDC59_RS23720 908dc0a54617a8315d81ab3095f1b22c 297 Pfam PF00892 EamA-like transporter family 3 135 7.0E-21 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CDC59_RS23720 908dc0a54617a8315d81ab3095f1b22c 297 Pfam PF00892 EamA-like transporter family 151 281 5.8E-16 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CDC59_RS02360 e2228aa8865a6b4fab6a5d589b7904e0 207 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 96 7.7E-32 T 29-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CDC59_RS02360 e2228aa8865a6b4fab6a5d589b7904e0 207 Gene3D G3DSA:1.10.1050.10 147 207 1.2E-15 T 29-03-2018 CDC59_RS02360 e2228aa8865a6b4fab6a5d589b7904e0 207 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 207 34.954 T 29-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 CDC59_RS02360 e2228aa8865a6b4fab6a5d589b7904e0 207 SMART SM00363 97 161 1.1E-14 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CDC59_RS02360 e2228aa8865a6b4fab6a5d589b7904e0 207 Pfam PF01479 S4 domain 98 144 3.3E-16 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CDC59_RS02360 e2228aa8865a6b4fab6a5d589b7904e0 207 Gene3D G3DSA:3.10.290.10 103 146 1.8E-15 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CDC59_RS02360 e2228aa8865a6b4fab6a5d589b7904e0 207 SMART SM01390 3 96 2.3E-47 T 29-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CDC59_RS02360 e2228aa8865a6b4fab6a5d589b7904e0 207 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 207 6.4E-79 T 29-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 CDC59_RS02360 e2228aa8865a6b4fab6a5d589b7904e0 207 SUPERFAMILY SSF55174 2 207 2.75E-66 T 29-03-2018 CDC59_RS02360 e2228aa8865a6b4fab6a5d589b7904e0 207 Gene3D G3DSA:1.10.1050.10 1 102 1.1E-41 T 29-03-2018 CDC59_RS02360 e2228aa8865a6b4fab6a5d589b7904e0 207 ProSitePatterns PS00632 Ribosomal protein S4 signature. 95 119 - T 29-03-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS05165 1b03204b38296a1ce2aea8d2e87d3667 194 Pfam PF05069 Phage virion morphogenesis family 10 187 6.7E-17 T 29-03-2018 IPR006522 Phage virion morphogensis protein CDC59_RS13445 4f42928bc5bc289742d05e99cce5ef32 159 Gene3D G3DSA:1.10.10.10 57 99 9.1E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS13445 4f42928bc5bc289742d05e99cce5ef32 159 Gene3D G3DSA:1.10.10.10 103 150 1.5E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS13445 4f42928bc5bc289742d05e99cce5ef32 159 Hamap MF_01114 Regulatory protein RecX [recX]. 5 152 13.037 T 29-03-2018 IPR003783 Regulatory protein RecX GO:0006282 CDC59_RS13445 4f42928bc5bc289742d05e99cce5ef32 159 Pfam PF02631 RecX family 34 147 3.0E-24 T 29-03-2018 IPR003783 Regulatory protein RecX GO:0006282 CDC59_RS13445 4f42928bc5bc289742d05e99cce5ef32 159 Gene3D G3DSA:1.10.10.10 8 55 8.5E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS03915 9d134f0f435938538da26e7f7a4dff45 232 Gene3D G3DSA:1.10.10.10 2 67 1.3E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS03915 9d134f0f435938538da26e7f7a4dff45 232 Pfam PF08279 HTH domain 10 63 1.1E-15 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 CDC59_RS03915 9d134f0f435938538da26e7f7a4dff45 232 Pfam PF13280 WYL domain 140 230 7.6E-18 T 29-03-2018 IPR026881 WYL domain CDC59_RS03915 9d134f0f435938538da26e7f7a4dff45 232 SUPERFAMILY SSF46785 8 65 1.51E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS21110 3d006082b15f22bfb8949308e17d4ddf 286 Gene3D G3DSA:1.10.10.10 2 88 3.6E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS21110 3d006082b15f22bfb8949308e17d4ddf 286 Gene3D G3DSA:3.40.190.10 175 254 1.6E-9 T 29-03-2018 CDC59_RS21110 3d006082b15f22bfb8949308e17d4ddf 286 SUPERFAMILY SSF46785 3 109 6.54E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS21110 3d006082b15f22bfb8949308e17d4ddf 286 Pfam PF03466 LysR substrate binding domain 90 281 6.1E-19 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS21110 3d006082b15f22bfb8949308e17d4ddf 286 SUPERFAMILY SSF53850 91 282 7.42E-19 T 29-03-2018 CDC59_RS21110 3d006082b15f22bfb8949308e17d4ddf 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 1.1E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS21110 3d006082b15f22bfb8949308e17d4ddf 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 1.1E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS21110 3d006082b15f22bfb8949308e17d4ddf 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 1.1E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS21110 3d006082b15f22bfb8949308e17d4ddf 286 Gene3D G3DSA:3.40.190.10 91 174 3.6E-9 T 29-03-2018 CDC59_RS21110 3d006082b15f22bfb8949308e17d4ddf 286 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 64 5.4E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS09735 9b0b4ffbed3c2f75a7a0a9f11e469186 144 SUPERFAMILY SSF54637 4 128 1.2E-31 T 29-03-2018 IPR029069 HotDog domain CDC59_RS09735 9b0b4ffbed3c2f75a7a0a9f11e469186 144 Gene3D G3DSA:3.10.129.10 5 132 6.6E-32 T 29-03-2018 CDC59_RS09735 9b0b4ffbed3c2f75a7a0a9f11e469186 144 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 14 125 7.9E-23 T 29-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 CDC59_RS09735 9b0b4ffbed3c2f75a7a0a9f11e469186 144 Pfam PF03061 Thioesterase superfamily 47 120 3.5E-14 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CDC59_RS03115 6f59f5b8b88813a9773abeb4c2c1edb8 389 ProSitePatterns PS01347 MraY family signature 1. 68 80 - T 29-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CDC59_RS03115 6f59f5b8b88813a9773abeb4c2c1edb8 389 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 68 78 8.3E-5 T 29-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CDC59_RS03115 6f59f5b8b88813a9773abeb4c2c1edb8 389 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 25 387 23.625 T 29-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CDC59_RS03115 6f59f5b8b88813a9773abeb4c2c1edb8 389 Pfam PF00953 Glycosyl transferase family 4 99 307 1.4E-34 T 29-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CDC59_RS03115 6f59f5b8b88813a9773abeb4c2c1edb8 389 ProSitePatterns PS01348 MraY family signature 2. 212 223 - T 29-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CDC59_RS03115 6f59f5b8b88813a9773abeb4c2c1edb8 389 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 180 389 7.5E-85 T 29-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CDC59_RS18325 a940c07cc912821ed7800b09f4042560 461 Pfam PF07690 Major Facilitator Superfamily 36 379 1.4E-12 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDC59_RS18325 a940c07cc912821ed7800b09f4042560 461 Gene3D G3DSA:1.20.1250.20 10 232 2.3E-13 T 29-03-2018 CDC59_RS18325 a940c07cc912821ed7800b09f4042560 461 Gene3D G3DSA:1.20.1250.20 238 459 2.6E-21 T 29-03-2018 CDC59_RS18325 a940c07cc912821ed7800b09f4042560 461 SUPERFAMILY SSF103473 7 456 4.97E-38 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS18325 a940c07cc912821ed7800b09f4042560 461 TIGRFAM TIGR00886 2A0108: nitrite transporter 27 413 2.9E-104 T 29-03-2018 IPR004737 Nitrate transporter GO:0015112|GO:0015113|GO:0015706|GO:0015707|GO:0016021 CDC59_RS08165 49b18015f08c174344dcaac48023f960 440 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 15 413 3.0E-150 T 29-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 CDC59_RS08165 49b18015f08c174344dcaac48023f960 440 SUPERFAMILY SSF55681 14 325 9.76E-99 T 29-03-2018 CDC59_RS08165 49b18015f08c174344dcaac48023f960 440 Gene3D G3DSA:3.30.930.10 7 332 2.2E-69 T 29-03-2018 CDC59_RS08165 49b18015f08c174344dcaac48023f960 440 Pfam PF13393 Histidyl-tRNA synthetase 17 319 3.2E-48 T 29-03-2018 CDC59_RS08165 49b18015f08c174344dcaac48023f960 440 Pfam PF03129 Anticodon binding domain 337 432 1.3E-9 T 29-03-2018 IPR004154 Anticodon-binding CDC59_RS08165 49b18015f08c174344dcaac48023f960 440 PIRSF PIRSF001549 9 435 2.7E-110 T 29-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 CDC59_RS08165 49b18015f08c174344dcaac48023f960 440 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 10 433 32.4 T 29-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 CDC59_RS08165 49b18015f08c174344dcaac48023f960 440 Gene3D G3DSA:3.40.50.800 333 436 4.2E-17 T 29-03-2018 IPR004154 Anticodon-binding CDC59_RS08165 49b18015f08c174344dcaac48023f960 440 SUPERFAMILY SSF52954 333 433 4.09E-20 T 29-03-2018 IPR004154 Anticodon-binding CDC59_RS04410 c778d955cc9e182444e5c346bdb03c51 743 SUPERFAMILY SSF58104 441 742 1.05E-64 T 29-03-2018 CDC59_RS04410 c778d955cc9e182444e5c346bdb03c51 743 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 525 708 1.6E-40 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CDC59_RS04410 c778d955cc9e182444e5c346bdb03c51 743 Pfam PF13675 Type IV pili methyl-accepting chemotaxis transducer N-term 94 197 9.6E-18 T 29-03-2018 IPR029095 NarX-like, N-terminal CDC59_RS04410 c778d955cc9e182444e5c346bdb03c51 743 SMART SM00283 476 741 4.3E-78 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CDC59_RS04410 c778d955cc9e182444e5c346bdb03c51 743 Gene3D G3DSA:1.10.287.950 511 743 3.6E-52 T 29-03-2018 CDC59_RS04410 c778d955cc9e182444e5c346bdb03c51 743 Gene3D G3DSA:1.10.287.950 267 510 0.022 T 29-03-2018 CDC59_RS04410 c778d955cc9e182444e5c346bdb03c51 743 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 508 537 1.0E-6 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS04410 c778d955cc9e182444e5c346bdb03c51 743 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 607 636 1.0E-6 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS14180 085a4a73d7f866db3d82dca7e5cd6e1f 206 PIRSF PIRSF006324 1 206 7.8E-60 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CDC59_RS14180 085a4a73d7f866db3d82dca7e5cd6e1f 206 Pfam PF01810 LysE type translocator 13 204 9.4E-39 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CDC59_RS16320 3796dec93661084f36e9f4f5a4932ec7 323 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 58 188 8.5E-61 T 29-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 CDC59_RS16320 3796dec93661084f36e9f4f5a4932ec7 323 Gene3D G3DSA:3.40.50.300 32 204 1.9E-24 T 29-03-2018 CDC59_RS16320 3796dec93661084f36e9f4f5a4932ec7 323 SMART SM00382 55 196 0.0038 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS16320 3796dec93661084f36e9f4f5a4932ec7 323 PIRSF PIRSF002849 4 323 1.3E-116 T 29-03-2018 CDC59_RS16320 3796dec93661084f36e9f4f5a4932ec7 323 SUPERFAMILY SSF52540 36 299 1.39E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS16320 3796dec93661084f36e9f4f5a4932ec7 323 Gene3D G3DSA:1.10.8.300 216 321 1.2E-24 T 29-03-2018 CDC59_RS11725 5b65d5f625cbddccc80041448a10314d 398 Gene3D G3DSA:2.40.110.10 121 218 9.2E-37 T 29-03-2018 CDC59_RS11725 5b65d5f625cbddccc80041448a10314d 398 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 119 3.0E-22 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CDC59_RS11725 5b65d5f625cbddccc80041448a10314d 398 SUPERFAMILY SSF56645 2 244 3.93E-78 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CDC59_RS11725 5b65d5f625cbddccc80041448a10314d 398 SUPERFAMILY SSF47203 231 397 2.74E-25 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CDC59_RS11725 5b65d5f625cbddccc80041448a10314d 398 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 219 1.1E-20 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CDC59_RS11725 5b65d5f625cbddccc80041448a10314d 398 Gene3D G3DSA:1.20.140.10 219 398 6.5E-42 T 29-03-2018 CDC59_RS11725 5b65d5f625cbddccc80041448a10314d 398 Gene3D G3DSA:1.10.540.10 1 120 1.6E-27 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CDC59_RS11725 5b65d5f625cbddccc80041448a10314d 398 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 395 4.1E-25 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CDC59_RS20650 58a5dfac63154d6f9b37e757cf16ab2b 283 Gene3D G3DSA:3.20.20.80 1 276 3.3E-21 T 29-03-2018 CDC59_RS20650 58a5dfac63154d6f9b37e757cf16ab2b 283 Pfam PF00704 Glycosyl hydrolases family 18 7 202 3.0E-9 T 29-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 CDC59_RS20650 58a5dfac63154d6f9b37e757cf16ab2b 283 SUPERFAMILY SSF51445 5 243 3.69E-20 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CDC59_RS01010 27347743cbdd3679c27c03227725f33e 705 Gene3D G3DSA:1.10.486.10 395 585 2.1E-35 T 29-03-2018 CDC59_RS01010 27347743cbdd3679c27c03227725f33e 705 Gene3D G3DSA:3.40.50.300 2 294 9.2E-48 T 29-03-2018 CDC59_RS01010 27347743cbdd3679c27c03227725f33e 705 Hamap MF_01920 ATP-dependent DNA helicase Rep [rep]. 7 699 37.623 T 29-03-2018 IPR005752 ATP-dependent DNA helicase Rep GO:0003677|GO:0004003|GO:0005524|GO:0006268 CDC59_RS01010 27347743cbdd3679c27c03227725f33e 705 Pfam PF00580 UvrD/REP helicase N-terminal domain 9 283 7.8E-68 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CDC59_RS01010 27347743cbdd3679c27c03227725f33e 705 Gene3D G3DSA:3.40.50.300 295 394 5.8E-26 T 29-03-2018 CDC59_RS01010 27347743cbdd3679c27c03227725f33e 705 SUPERFAMILY SSF52540 574 669 1.61E-149 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS01010 27347743cbdd3679c27c03227725f33e 705 SUPERFAMILY SSF52540 7 533 1.61E-149 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS01010 27347743cbdd3679c27c03227725f33e 705 Pfam PF13361 UvrD-like helicase C-terminal domain 289 439 7.3E-31 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CDC59_RS01010 27347743cbdd3679c27c03227725f33e 705 Pfam PF13361 UvrD-like helicase C-terminal domain 511 648 1.5E-28 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CDC59_RS12630 e90a70af7f460a2f89c63a241e752c5c 610 Pfam PF00072 Response regulator receiver domain 485 593 3.4E-15 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS12630 e90a70af7f460a2f89c63a241e752c5c 610 SUPERFAMILY SSF52172 485 606 6.12E-24 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS12630 e90a70af7f460a2f89c63a241e752c5c 610 SUPERFAMILY SSF47384 217 299 1.26E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS12630 e90a70af7f460a2f89c63a241e752c5c 610 Pfam PF00512 His Kinase A (phospho-acceptor) domain 235 298 6.8E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS12630 e90a70af7f460a2f89c63a241e752c5c 610 SMART SM00388 234 299 4.3E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS12630 e90a70af7f460a2f89c63a241e752c5c 610 SMART SM00387 345 456 8.0E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS12630 e90a70af7f460a2f89c63a241e752c5c 610 Gene3D G3DSA:3.30.565.10 294 454 2.1E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS12630 e90a70af7f460a2f89c63a241e752c5c 610 SMART SM00448 483 595 1.2E-21 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS12630 e90a70af7f460a2f89c63a241e752c5c 610 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 349 453 7.6E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS12630 e90a70af7f460a2f89c63a241e752c5c 610 Gene3D G3DSA:3.40.50.2300 469 608 1.0E-23 T 29-03-2018 CDC59_RS12630 e90a70af7f460a2f89c63a241e752c5c 610 SUPERFAMILY SSF55874 289 452 1.7E-40 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS12630 e90a70af7f460a2f89c63a241e752c5c 610 PRINTS PR00344 Bacterial sensor protein C-terminal signature 399 409 2.1E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS12630 e90a70af7f460a2f89c63a241e752c5c 610 PRINTS PR00344 Bacterial sensor protein C-terminal signature 416 434 2.1E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS12630 e90a70af7f460a2f89c63a241e752c5c 610 PRINTS PR00344 Bacterial sensor protein C-terminal signature 381 395 2.1E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS12630 e90a70af7f460a2f89c63a241e752c5c 610 PRINTS PR00344 Bacterial sensor protein C-terminal signature 440 453 2.1E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS12630 e90a70af7f460a2f89c63a241e752c5c 610 Gene3D G3DSA:1.10.287.130 225 293 4.0E-10 T 29-03-2018 CDC59_RS22100 9edc16dfbcbb97b0b7da44f69abfdc77 126 SUPERFAMILY SSF54593 1 122 2.48E-26 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CDC59_RS22100 9edc16dfbcbb97b0b7da44f69abfdc77 126 Gene3D G3DSA:3.10.180.10 6 125 8.9E-27 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CDC59_RS22100 9edc16dfbcbb97b0b7da44f69abfdc77 126 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 121 1.8E-10 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CDC59_RS03160 c4833e7f48bfbca45598649f5976aea8 166 Pfam PF08534 Redoxin 3 163 7.9E-40 T 29-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 CDC59_RS03160 c4833e7f48bfbca45598649f5976aea8 166 SUPERFAMILY SSF52833 1 165 1.84E-35 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS03160 c4833e7f48bfbca45598649f5976aea8 166 Gene3D G3DSA:3.40.30.10 1 166 6.2E-25 T 29-03-2018 CDC59_RS21680 ef4bbf81bee165733d4a9ca9790fd636 914 Pfam PF00563 EAL domain 654 889 2.0E-70 T 29-03-2018 IPR001633 EAL domain CDC59_RS21680 ef4bbf81bee165733d4a9ca9790fd636 914 Gene3D G3DSA:3.30.450.40 187 331 1.3E-21 T 29-03-2018 IPR029016 GAF domain-like CDC59_RS21680 ef4bbf81bee165733d4a9ca9790fd636 914 SMART SM00065 188 340 0.0015 T 29-03-2018 IPR003018 GAF domain GO:0005515 CDC59_RS21680 ef4bbf81bee165733d4a9ca9790fd636 914 SMART SM00267 466 638 1.0E-63 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS21680 ef4bbf81bee165733d4a9ca9790fd636 914 Gene3D G3DSA:3.30.70.270 473 638 2.9E-61 T 29-03-2018 CDC59_RS21680 ef4bbf81bee165733d4a9ca9790fd636 914 Gene3D G3DSA:3.30.450.20 36 186 8.5E-11 T 29-03-2018 CDC59_RS21680 ef4bbf81bee165733d4a9ca9790fd636 914 Pfam PF13426 PAS domain 355 465 2.2E-5 T 29-03-2018 IPR000014 PAS domain CDC59_RS21680 ef4bbf81bee165733d4a9ca9790fd636 914 SUPERFAMILY SSF141868 654 902 2.09E-89 T 29-03-2018 IPR001633 EAL domain CDC59_RS21680 ef4bbf81bee165733d4a9ca9790fd636 914 SUPERFAMILY SSF55073 482 639 5.65E-49 T 29-03-2018 IPR029787 Nucleotide cyclase CDC59_RS21680 ef4bbf81bee165733d4a9ca9790fd636 914 Pfam PF13185 GAF domain 187 331 4.5E-14 T 29-03-2018 IPR003018 GAF domain GO:0005515 CDC59_RS21680 ef4bbf81bee165733d4a9ca9790fd636 914 Pfam PF00990 Diguanylate cyclase, GGDEF domain 477 634 2.5E-48 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS21680 ef4bbf81bee165733d4a9ca9790fd636 914 SMART SM00052 648 894 1.0E-117 T 29-03-2018 IPR001633 EAL domain CDC59_RS21680 ef4bbf81bee165733d4a9ca9790fd636 914 SUPERFAMILY SSF55781 158 331 2.62E-21 T 29-03-2018 IPR029016 GAF domain-like CDC59_RS21680 ef4bbf81bee165733d4a9ca9790fd636 914 Gene3D G3DSA:3.20.20.450 639 898 5.9E-101 T 29-03-2018 IPR001633 EAL domain CDC59_RS21680 ef4bbf81bee165733d4a9ca9790fd636 914 SUPERFAMILY SSF55785 335 464 1.4E-16 T 29-03-2018 IPR000014 PAS domain CDC59_RS21680 ef4bbf81bee165733d4a9ca9790fd636 914 SUPERFAMILY SSF55785 40 139 3.06E-7 T 29-03-2018 IPR000014 PAS domain CDC59_RS21680 ef4bbf81bee165733d4a9ca9790fd636 914 Gene3D G3DSA:3.30.450.20 332 472 2.3E-23 T 29-03-2018 CDC59_RS21680 ef4bbf81bee165733d4a9ca9790fd636 914 SMART SM00091 39 105 8.3 T 29-03-2018 IPR000014 PAS domain CDC59_RS21680 ef4bbf81bee165733d4a9ca9790fd636 914 SMART SM00091 344 414 6.5E-4 T 29-03-2018 IPR000014 PAS domain CDC59_RS21680 ef4bbf81bee165733d4a9ca9790fd636 914 Pfam PF13188 PAS domain 41 88 0.013 T 29-03-2018 IPR000014 PAS domain CDC59_RS21680 ef4bbf81bee165733d4a9ca9790fd636 914 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 340 473 2.4E-11 T 29-03-2018 IPR000014 PAS domain CDC59_RS21680 ef4bbf81bee165733d4a9ca9790fd636 914 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 473 636 6.5E-41 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS21680 ef4bbf81bee165733d4a9ca9790fd636 914 PIRSF PIRSF005925 463 912 2.3E-135 T 29-03-2018 IPR012226 Diguanylate cyclase/phosphodiesterase CDC59_RS21680 ef4bbf81bee165733d4a9ca9790fd636 914 PIRSF PIRSF005925 339 471 3.8 T 29-03-2018 IPR012226 Diguanylate cyclase/phosphodiesterase CDC59_RS21680 ef4bbf81bee165733d4a9ca9790fd636 914 PIRSF PIRSF005925 162 379 1.2E-31 T 29-03-2018 IPR012226 Diguanylate cyclase/phosphodiesterase CDC59_RS21155 248a51afeb26a0dae0c430f290cb3405 388 Gene3D G3DSA:2.40.50.100 216 319 0.012 T 29-03-2018 CDC59_RS21155 248a51afeb26a0dae0c430f290cb3405 388 Gene3D G3DSA:2.40.50.100 105 215 1.6E-13 T 29-03-2018 CDC59_RS21155 248a51afeb26a0dae0c430f290cb3405 388 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 74 381 7.5E-44 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 CDC59_RS21155 248a51afeb26a0dae0c430f290cb3405 388 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 86 304 1.1E-59 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CDC59_RS21155 248a51afeb26a0dae0c430f290cb3405 388 SUPERFAMILY SSF111369 105 312 7.98E-23 T 29-03-2018 CDC59_RS21645 306a1555f72c26421edbe512b31d39b4 181 SUPERFAMILY SSF46894 107 172 1.46E-19 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CDC59_RS21645 306a1555f72c26421edbe512b31d39b4 181 SMART SM00421 113 170 5.1E-21 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS21645 306a1555f72c26421edbe512b31d39b4 181 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 146 158 1.5E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS21645 306a1555f72c26421edbe512b31d39b4 181 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 116 130 1.5E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS21645 306a1555f72c26421edbe512b31d39b4 181 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 130 146 1.5E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS21645 306a1555f72c26421edbe512b31d39b4 181 Gene3D G3DSA:1.10.10.10 56 178 2.4E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS21645 306a1555f72c26421edbe512b31d39b4 181 Pfam PF00196 Bacterial regulatory proteins, luxR family 115 169 8.3E-19 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS18340 c217f2cd7a0663da24940a2ac33219f3 517 Pfam PF14711 Respiratory nitrate reductase beta C-terminal 358 435 4.1E-30 T 29-03-2018 IPR029263 Respiratory nitrate reductase beta, C-terminal KEGG: 00910+1.7.99.4 CDC59_RS18340 c217f2cd7a0663da24940a2ac33219f3 517 SUPERFAMILY SSF54862 1 497 7.53E-181 T 29-03-2018 CDC59_RS18340 c217f2cd7a0663da24940a2ac33219f3 517 Pfam PF13247 4Fe-4S dicluster domain 175 271 9.9E-37 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CDC59_RS18340 c217f2cd7a0663da24940a2ac33219f3 517 Gene3D G3DSA:1.10.3650.10 363 434 1.9E-30 T 29-03-2018 CDC59_RS18340 c217f2cd7a0663da24940a2ac33219f3 517 Gene3D G3DSA:3.30.70.20 5 197 5.0E-28 T 29-03-2018 CDC59_RS18340 c217f2cd7a0663da24940a2ac33219f3 517 Gene3D G3DSA:3.30.70.20 236 362 7.1E-30 T 29-03-2018 CDC59_RS18340 c217f2cd7a0663da24940a2ac33219f3 517 TIGRFAM TIGR01660 narH: nitrate reductase, beta subunit 1 488 8.9E-287 T 29-03-2018 IPR006547 Nitrate reductase, beta subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.99.4 CDC59_RS18340 c217f2cd7a0663da24940a2ac33219f3 517 Gene3D G3DSA:3.30.70.20 198 235 1.7E-18 T 29-03-2018 CDC59_RS08680 d461d445aa411842c55f635a37b8fa4a 150 Pfam PF03948 Ribosomal protein L9, C-terminal domain 64 145 5.1E-27 T 29-03-2018 IPR020069 Ribosomal protein L9, C-terminal CDC59_RS08680 d461d445aa411842c55f635a37b8fa4a 150 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 47 2.1E-21 T 29-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS08680 d461d445aa411842c55f635a37b8fa4a 150 Gene3D G3DSA:3.40.5.10 1 49 6.0E-22 T 29-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS08680 d461d445aa411842c55f635a37b8fa4a 150 SUPERFAMILY SSF55653 60 147 1.09E-26 T 29-03-2018 IPR020069 Ribosomal protein L9, C-terminal CDC59_RS08680 d461d445aa411842c55f635a37b8fa4a 150 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 29-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS08680 d461d445aa411842c55f635a37b8fa4a 150 Gene3D G3DSA:3.10.430.100 63 147 1.2E-27 T 29-03-2018 IPR020069 Ribosomal protein L9, C-terminal CDC59_RS08680 d461d445aa411842c55f635a37b8fa4a 150 SUPERFAMILY SSF55658 1 56 1.12E-17 T 29-03-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal CDC59_RS08680 d461d445aa411842c55f635a37b8fa4a 150 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 146 1.0E-46 T 29-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS08680 d461d445aa411842c55f635a37b8fa4a 150 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 148 26.261 T 29-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS22195 7a3cefeed02a9217e74f2cf53fd9b02f 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 135 1.5E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS22195 7a3cefeed02a9217e74f2cf53fd9b02f 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 1.5E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS22195 7a3cefeed02a9217e74f2cf53fd9b02f 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 165 1.5E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS22195 7a3cefeed02a9217e74f2cf53fd9b02f 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 3.0E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS22195 7a3cefeed02a9217e74f2cf53fd9b02f 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 3.0E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS22195 7a3cefeed02a9217e74f2cf53fd9b02f 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 3.0E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS22195 7a3cefeed02a9217e74f2cf53fd9b02f 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 3.0E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS22195 7a3cefeed02a9217e74f2cf53fd9b02f 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 3.0E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS22195 7a3cefeed02a9217e74f2cf53fd9b02f 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 198 218 3.0E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS22195 7a3cefeed02a9217e74f2cf53fd9b02f 236 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 14 177 0.0022 T 29-03-2018 CDC59_RS22195 7a3cefeed02a9217e74f2cf53fd9b02f 236 Gene3D G3DSA:3.40.50.720 150 236 1.5E-22 T 29-03-2018 CDC59_RS22195 7a3cefeed02a9217e74f2cf53fd9b02f 236 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 20 234 2.5E-42 T 29-03-2018 CDC59_RS22195 7a3cefeed02a9217e74f2cf53fd9b02f 236 SUPERFAMILY SSF51735 14 235 1.73E-58 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS22195 7a3cefeed02a9217e74f2cf53fd9b02f 236 Gene3D G3DSA:3.40.50.720 11 149 1.5E-36 T 29-03-2018 CDC59_RS12410 cbed7a8e30c74e06171aca219161f314 142 SUPERFAMILY SSF102400 1 139 6.15E-40 T 29-03-2018 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 CDC59_RS12410 cbed7a8e30c74e06171aca219161f314 142 Pfam PF04364 DNA polymerase III chi subunit, HolC 1 134 9.0E-38 T 29-03-2018 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 CDC59_RS12410 cbed7a8e30c74e06171aca219161f314 142 Gene3D G3DSA:3.40.50.10110 1 140 9.1E-43 T 29-03-2018 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 CDC59_RS18740 263bd5e7edc9bc218521bb704acfd0e7 578 Gene3D G3DSA:3.20.20.370 288 577 4.7E-10 T 29-03-2018 CDC59_RS18740 263bd5e7edc9bc218521bb704acfd0e7 578 Pfam PF10096 Uncharacterized protein conserved in bacteria (DUF2334) 288 557 6.8E-54 T 29-03-2018 IPR018763 Protein of unknown function DUF2334 CDC59_RS18740 263bd5e7edc9bc218521bb704acfd0e7 578 SUPERFAMILY SSF48208 98 254 3.3E-7 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CDC59_RS07770 10b2bb1f1e65b3c333488cfa06704cf9 294 PIRSF PIRSF001365 1 294 5.6E-92 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CDC59_RS07770 10b2bb1f1e65b3c333488cfa06704cf9 294 Pfam PF00701 Dihydrodipicolinate synthetase family 4 288 1.2E-102 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CDC59_RS07770 10b2bb1f1e65b3c333488cfa06704cf9 294 SMART SM01130 3 291 1.8E-143 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CDC59_RS07770 10b2bb1f1e65b3c333488cfa06704cf9 294 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 135 165 - T 29-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 CDC59_RS07770 10b2bb1f1e65b3c333488cfa06704cf9 294 PRINTS PR00146 Dihydrodipicolinate synthase signature 105 121 9.5E-34 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CDC59_RS07770 10b2bb1f1e65b3c333488cfa06704cf9 294 PRINTS PR00146 Dihydrodipicolinate synthase signature 130 147 9.5E-34 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CDC59_RS07770 10b2bb1f1e65b3c333488cfa06704cf9 294 PRINTS PR00146 Dihydrodipicolinate synthase signature 37 58 9.5E-34 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CDC59_RS07770 10b2bb1f1e65b3c333488cfa06704cf9 294 PRINTS PR00146 Dihydrodipicolinate synthase signature 73 91 9.5E-34 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CDC59_RS07770 10b2bb1f1e65b3c333488cfa06704cf9 294 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 7 289 5.8E-110 T 29-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CDC59_RS07770 10b2bb1f1e65b3c333488cfa06704cf9 294 SUPERFAMILY SSF51569 1 291 1.36E-104 T 29-03-2018 CDC59_RS07770 10b2bb1f1e65b3c333488cfa06704cf9 294 Gene3D G3DSA:3.20.20.70 1 294 7.4E-100 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS07770 10b2bb1f1e65b3c333488cfa06704cf9 294 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 3 289 67.124 T 29-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CDC59_RS00605 b76282e1d99c59877ae513dcb855dfe2 681 PRINTS PR01607 Apyrase family signature 330 350 1.4E-24 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CDC59_RS00605 b76282e1d99c59877ae513dcb855dfe2 681 PRINTS PR01607 Apyrase family signature 564 583 1.4E-24 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CDC59_RS00605 b76282e1d99c59877ae513dcb855dfe2 681 PRINTS PR01607 Apyrase family signature 258 275 1.4E-24 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CDC59_RS00605 b76282e1d99c59877ae513dcb855dfe2 681 PRINTS PR01607 Apyrase family signature 42 60 1.4E-24 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CDC59_RS00605 b76282e1d99c59877ae513dcb855dfe2 681 PRINTS PR01607 Apyrase family signature 474 497 1.4E-24 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CDC59_RS00605 b76282e1d99c59877ae513dcb855dfe2 681 PRINTS PR01607 Apyrase family signature 286 309 1.4E-24 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CDC59_RS00605 b76282e1d99c59877ae513dcb855dfe2 681 SUPERFAMILY SSF56300 40 399 1.66E-72 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CDC59_RS00605 b76282e1d99c59877ae513dcb855dfe2 681 Gene3D G3DSA:3.60.21.10 33 400 1.3E-67 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CDC59_RS00605 b76282e1d99c59877ae513dcb855dfe2 681 ProSitePatterns PS00786 5'-nucleotidase signature 2. 130 141 - T 29-03-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CDC59_RS00605 b76282e1d99c59877ae513dcb855dfe2 681 Gene3D G3DSA:3.90.780.10 401 631 1.8E-48 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CDC59_RS00605 b76282e1d99c59877ae513dcb855dfe2 681 SUPERFAMILY SSF55816 400 620 2.09E-38 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CDC59_RS00605 b76282e1d99c59877ae513dcb855dfe2 681 Pfam PF02872 5'-nucleotidase, C-terminal domain 403 589 7.7E-22 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CDC59_RS13265 9b039655ac7d205c3d2954b44281e988 391 SUPERFAMILY SSF51338 348 379 1.14E-5 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CDC59_RS13265 9b039655ac7d205c3d2954b44281e988 391 SUPERFAMILY SSF51338 23 58 1.14E-5 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CDC59_RS13265 9b039655ac7d205c3d2954b44281e988 391 Gene3D G3DSA:3.20.20.140 39 376 1.1E-21 T 29-03-2018 CDC59_RS13265 9b039655ac7d205c3d2954b44281e988 391 PIRSF PIRSF038971 13 382 1.7E-106 T 29-03-2018 IPR012696 Phosphonate metabolism PhnM GO:0019700 KEGG: 00440+3.6.1.63|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CDC59_RS13265 9b039655ac7d205c3d2954b44281e988 391 SUPERFAMILY SSF51556 211 347 6.29E-8 T 29-03-2018 IPR032466 Metal-dependent hydrolase CDC59_RS13265 9b039655ac7d205c3d2954b44281e988 391 SUPERFAMILY SSF51556 58 172 6.29E-8 T 29-03-2018 IPR032466 Metal-dependent hydrolase CDC59_RS13265 9b039655ac7d205c3d2954b44281e988 391 Pfam PF01979 Amidohydrolase family 171 372 7.1E-5 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CDC59_RS22170 aeb10a7e20d5ac49b4623166ffc80674 389 Gene3D G3DSA:1.20.1090.10 189 388 5.6E-62 T 29-03-2018 CDC59_RS22170 aeb10a7e20d5ac49b4623166ffc80674 389 Pfam PF00465 Iron-containing alcohol dehydrogenase 12 380 1.6E-111 T 29-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CDC59_RS22170 aeb10a7e20d5ac49b4623166ffc80674 389 SUPERFAMILY SSF56796 5 386 1.96E-116 T 29-03-2018 CDC59_RS22170 aeb10a7e20d5ac49b4623166ffc80674 389 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 177 205 - T 29-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 CDC59_RS22170 aeb10a7e20d5ac49b4623166ffc80674 389 Gene3D G3DSA:3.40.50.1970 1 188 2.0E-41 T 29-03-2018 CDC59_RS15565 f1cc0b2e11612be20c4b9bd41b2fc9b4 164 Gene3D G3DSA:3.40.630.30 10 163 1.1E-23 T 29-03-2018 CDC59_RS15565 f1cc0b2e11612be20c4b9bd41b2fc9b4 164 Pfam PF00583 Acetyltransferase (GNAT) family 40 145 1.3E-11 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CDC59_RS15565 f1cc0b2e11612be20c4b9bd41b2fc9b4 164 SUPERFAMILY SSF55729 9 150 1.52E-23 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDC59_RS10115 fb3cc94386c324bb40d6c6b5e3339fd6 1372 SUPERFAMILY SSF55326 662 862 8.63E-64 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CDC59_RS10115 fb3cc94386c324bb40d6c6b5e3339fd6 1372 SUPERFAMILY SSF52317 1112 1371 1.64E-87 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CDC59_RS10115 fb3cc94386c324bb40d6c6b5e3339fd6 1372 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 1116 1371 8.6E-100 T 29-03-2018 CDC59_RS10115 fb3cc94386c324bb40d6c6b5e3339fd6 1372 SUPERFAMILY SSF109736 182 237 9.15E-21 T 29-03-2018 CDC59_RS10115 fb3cc94386c324bb40d6c6b5e3339fd6 1372 Hamap MF_00419 Phosphoribosylformylglycinamidine synthase [purL]. 4 1372 21.348 T 29-03-2018 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CDC59_RS10115 fb3cc94386c324bb40d6c6b5e3339fd6 1372 SMART SM01211 1116 1371 6.1E-142 T 29-03-2018 CDC59_RS10115 fb3cc94386c324bb40d6c6b5e3339fd6 1372 SUPERFAMILY SSF55326 238 465 2.58E-57 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CDC59_RS10115 fb3cc94386c324bb40d6c6b5e3339fd6 1372 SUPERFAMILY SSF82697 4 164 2.88E-41 T 29-03-2018 CDC59_RS10115 fb3cc94386c324bb40d6c6b5e3339fd6 1372 Gene3D G3DSA:3.30.1330.10 200 235 9.1E-4 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CDC59_RS10115 fb3cc94386c324bb40d6c6b5e3339fd6 1372 Gene3D G3DSA:3.30.1330.10 236 463 4.6E-48 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CDC59_RS10115 fb3cc94386c324bb40d6c6b5e3339fd6 1372 Gene3D G3DSA:3.30.1330.10 655 859 8.4E-22 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CDC59_RS10115 fb3cc94386c324bb40d6c6b5e3339fd6 1372 Gene3D G3DSA:3.40.50.880 1115 1371 3.4E-28 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CDC59_RS10115 fb3cc94386c324bb40d6c6b5e3339fd6 1372 TIGRFAM TIGR01735 FGAM_synt: phosphoribosylformylglycinamidine synthase 8 1371 0.0 T 29-03-2018 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CDC59_RS10115 fb3cc94386c324bb40d6c6b5e3339fd6 1372 SUPERFAMILY SSF56042 470 698 1.35E-48 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CDC59_RS10115 fb3cc94386c324bb40d6c6b5e3339fd6 1372 SUPERFAMILY SSF56042 875 1109 6.43E-52 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CDC59_RS10115 fb3cc94386c324bb40d6c6b5e3339fd6 1372 Pfam PF02769 AIR synthase related protein, C-terminal domain 470 627 9.6E-24 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CDC59_RS10115 fb3cc94386c324bb40d6c6b5e3339fd6 1372 Pfam PF02769 AIR synthase related protein, C-terminal domain 889 1033 3.9E-12 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CDC59_RS10115 fb3cc94386c324bb40d6c6b5e3339fd6 1372 Gene3D G3DSA:3.90.650.10 870 1070 3.1E-33 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CDC59_RS10115 fb3cc94386c324bb40d6c6b5e3339fd6 1372 Gene3D G3DSA:3.90.650.10 464 649 1.7E-27 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CDC59_RS00855 8624d78ba346a17ef90a4caf9ef822df 138 Gene3D G3DSA:2.60.15.10 1 89 2.6E-31 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS00855 8624d78ba346a17ef90a4caf9ef822df 138 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 9 89 4.0E-35 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS00855 8624d78ba346a17ef90a4caf9ef822df 138 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 2 130 21.762 T 29-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS00855 8624d78ba346a17ef90a4caf9ef822df 138 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 88 131 5.5E-8 T 29-03-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS00855 8624d78ba346a17ef90a4caf9ef822df 138 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 3 131 2.5E-44 T 29-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS00855 8624d78ba346a17ef90a4caf9ef822df 138 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 4 83 1.7E-31 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS00855 8624d78ba346a17ef90a4caf9ef822df 138 Gene3D G3DSA:1.20.5.440 90 130 4.7E-8 T 29-03-2018 CDC59_RS00855 8624d78ba346a17ef90a4caf9ef822df 138 SUPERFAMILY SSF51344 3 85 8.76E-26 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS00855 8624d78ba346a17ef90a4caf9ef822df 138 SUPERFAMILY SSF46604 87 135 6.54E-12 T 29-03-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS00365 24effb61c07aa8772a024baf34306ae3 287 Gene3D G3DSA:3.30.65.10 232 287 4.6E-10 T 29-03-2018 CDC59_RS00365 24effb61c07aa8772a024baf34306ae3 287 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 250 285 2.0E-6 T 29-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CDC59_RS00365 24effb61c07aa8772a024baf34306ae3 287 SUPERFAMILY SSF52980 111 225 2.12E-18 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CDC59_RS00365 24effb61c07aa8772a024baf34306ae3 287 Gene3D G3DSA:3.40.1350.10 97 231 4.5E-21 T 29-03-2018 CDC59_RS00365 24effb61c07aa8772a024baf34306ae3 287 SUPERFAMILY SSF57783 242 285 3.91E-6 T 29-03-2018 CDC59_RS00365 24effb61c07aa8772a024baf34306ae3 287 Pfam PF04471 Restriction endonuclease 107 222 1.1E-22 T 29-03-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 CDC59_RS17490 a8093f2593fcac5a1e03ba46d44ffd96 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS17490 a8093f2593fcac5a1e03ba46d44ffd96 328 Pfam PF05598 Transposase domain (DUF772) 51 126 2.7E-23 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS09970 a8093f2593fcac5a1e03ba46d44ffd96 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS09970 a8093f2593fcac5a1e03ba46d44ffd96 328 Pfam PF05598 Transposase domain (DUF772) 51 126 2.7E-23 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS21250 a8093f2593fcac5a1e03ba46d44ffd96 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS21250 a8093f2593fcac5a1e03ba46d44ffd96 328 Pfam PF05598 Transposase domain (DUF772) 51 126 2.7E-23 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS21070 a8093f2593fcac5a1e03ba46d44ffd96 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS21070 a8093f2593fcac5a1e03ba46d44ffd96 328 Pfam PF05598 Transposase domain (DUF772) 51 126 2.7E-23 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS18015 a8093f2593fcac5a1e03ba46d44ffd96 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS18015 a8093f2593fcac5a1e03ba46d44ffd96 328 Pfam PF05598 Transposase domain (DUF772) 51 126 2.7E-23 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS22405 a8093f2593fcac5a1e03ba46d44ffd96 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS22405 a8093f2593fcac5a1e03ba46d44ffd96 328 Pfam PF05598 Transposase domain (DUF772) 51 126 2.7E-23 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS16965 a8093f2593fcac5a1e03ba46d44ffd96 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS16965 a8093f2593fcac5a1e03ba46d44ffd96 328 Pfam PF05598 Transposase domain (DUF772) 51 126 2.7E-23 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS16960 e1e4c71981871056f712d9a9c4cafba8 894 SUPERFAMILY SSF141868 641 889 1.03E-77 T 29-03-2018 IPR001633 EAL domain CDC59_RS16960 e1e4c71981871056f712d9a9c4cafba8 894 Pfam PF00990 Diguanylate cyclase, GGDEF domain 471 621 3.2E-38 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS16960 e1e4c71981871056f712d9a9c4cafba8 894 Gene3D G3DSA:3.30.450.20 323 467 7.8E-15 T 29-03-2018 CDC59_RS16960 e1e4c71981871056f712d9a9c4cafba8 894 SMART SM00052 635 881 3.4E-91 T 29-03-2018 IPR001633 EAL domain CDC59_RS16960 e1e4c71981871056f712d9a9c4cafba8 894 SMART SM00091 336 406 0.092 T 29-03-2018 IPR000014 PAS domain CDC59_RS16960 e1e4c71981871056f712d9a9c4cafba8 894 SMART SM00091 5 73 10.0 T 29-03-2018 IPR000014 PAS domain CDC59_RS16960 e1e4c71981871056f712d9a9c4cafba8 894 Gene3D G3DSA:3.30.70.270 468 637 1.4E-53 T 29-03-2018 CDC59_RS16960 e1e4c71981871056f712d9a9c4cafba8 894 Gene3D G3DSA:3.30.450.20 7 138 0.011 T 29-03-2018 CDC59_RS16960 e1e4c71981871056f712d9a9c4cafba8 894 SUPERFAMILY SSF55785 329 456 1.15E-11 T 29-03-2018 IPR000014 PAS domain CDC59_RS16960 e1e4c71981871056f712d9a9c4cafba8 894 Gene3D G3DSA:3.20.20.450 638 892 2.8E-88 T 29-03-2018 IPR001633 EAL domain CDC59_RS16960 e1e4c71981871056f712d9a9c4cafba8 894 SMART SM00267 458 625 6.3E-49 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS16960 e1e4c71981871056f712d9a9c4cafba8 894 Pfam PF00563 EAL domain 641 876 1.2E-66 T 29-03-2018 IPR001633 EAL domain CDC59_RS16960 e1e4c71981871056f712d9a9c4cafba8 894 SUPERFAMILY SSF55073 474 626 2.59E-41 T 29-03-2018 IPR029787 Nucleotide cyclase CDC59_RS16960 e1e4c71981871056f712d9a9c4cafba8 894 Pfam PF08448 PAS fold 342 459 9.5E-8 T 29-03-2018 IPR013656 PAS fold-4 CDC59_RS16960 e1e4c71981871056f712d9a9c4cafba8 894 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 469 623 1.5E-32 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS22220 546c4733b5a7a45fa939004bec1b2bf7 485 Gene3D G3DSA:1.20.1250.20 264 482 2.0E-22 T 29-03-2018 CDC59_RS22220 546c4733b5a7a45fa939004bec1b2bf7 485 Pfam PF07690 Major Facilitator Superfamily 31 421 1.3E-44 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDC59_RS22220 546c4733b5a7a45fa939004bec1b2bf7 485 Gene3D G3DSA:1.20.1250.20 18 210 2.5E-32 T 29-03-2018 CDC59_RS22220 546c4733b5a7a45fa939004bec1b2bf7 485 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 30 429 3.9E-72 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CDC59_RS22220 546c4733b5a7a45fa939004bec1b2bf7 485 PRINTS PR01036 Tetracycline resistance protein TetB signature 120 140 7.3E-8 T 29-03-2018 CDC59_RS22220 546c4733b5a7a45fa939004bec1b2bf7 485 PRINTS PR01036 Tetracycline resistance protein TetB signature 412 431 7.3E-8 T 29-03-2018 CDC59_RS22220 546c4733b5a7a45fa939004bec1b2bf7 485 PRINTS PR01036 Tetracycline resistance protein TetB signature 29 53 7.3E-8 T 29-03-2018 CDC59_RS22220 546c4733b5a7a45fa939004bec1b2bf7 485 PRINTS PR01036 Tetracycline resistance protein TetB signature 150 174 7.3E-8 T 29-03-2018 CDC59_RS22220 546c4733b5a7a45fa939004bec1b2bf7 485 SUPERFAMILY SSF103473 12 209 1.96E-62 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS22220 546c4733b5a7a45fa939004bec1b2bf7 485 SUPERFAMILY SSF103473 260 474 1.96E-62 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS19065 00fa332a53491b6f03cdb2a1707fcfa0 437 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 21 194 8.8E-12 T 29-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CDC59_RS19065 00fa332a53491b6f03cdb2a1707fcfa0 437 Hamap MF_00027 Cobyrinate a,c-diamide synthase [cbiA]. 13 428 37.19 T 29-03-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 CDC59_RS19065 00fa332a53491b6f03cdb2a1707fcfa0 437 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 21 433 5.2E-81 T 29-03-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 CDC59_RS19065 00fa332a53491b6f03cdb2a1707fcfa0 437 SUPERFAMILY SSF52540 15 200 1.3E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS19065 00fa332a53491b6f03cdb2a1707fcfa0 437 Gene3D G3DSA:3.40.50.880 198 424 4.5E-23 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CDC59_RS19065 00fa332a53491b6f03cdb2a1707fcfa0 437 Gene3D G3DSA:3.40.50.300 12 197 1.8E-29 T 29-03-2018 CDC59_RS19065 00fa332a53491b6f03cdb2a1707fcfa0 437 SUPERFAMILY SSF52317 244 435 1.68E-33 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CDC59_RS19065 00fa332a53491b6f03cdb2a1707fcfa0 437 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 246 427 1.1E-32 T 29-03-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 CDC59_RS03790 7c7fcfb35802bb79ae3a51c16b1007bc 243 SUPERFAMILY SSF48008 103 231 8.89E-20 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CDC59_RS03790 7c7fcfb35802bb79ae3a51c16b1007bc 243 Pfam PF00392 Bacterial regulatory proteins, gntR family 27 83 9.5E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDC59_RS03790 7c7fcfb35802bb79ae3a51c16b1007bc 243 Pfam PF07729 FCD domain 104 222 3.2E-19 T 29-03-2018 IPR011711 GntR, C-terminal CDC59_RS03790 7c7fcfb35802bb79ae3a51c16b1007bc 243 Gene3D G3DSA:1.20.120.530 80 237 2.0E-24 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CDC59_RS03790 7c7fcfb35802bb79ae3a51c16b1007bc 243 Gene3D G3DSA:1.10.10.10 2 79 3.7E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS03790 7c7fcfb35802bb79ae3a51c16b1007bc 243 SMART SM00895 93 223 1.7E-13 T 29-03-2018 IPR011711 GntR, C-terminal CDC59_RS03790 7c7fcfb35802bb79ae3a51c16b1007bc 243 SMART SM00345 25 83 1.4E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDC59_RS03790 7c7fcfb35802bb79ae3a51c16b1007bc 243 SUPERFAMILY SSF46785 20 87 6.81E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS02900 303daf5868088947d60c33e5f0e085b3 267 Gene3D G3DSA:3.20.20.70 11 267 7.3E-73 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS02900 303daf5868088947d60c33e5f0e085b3 267 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 61 79 - T 29-03-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 CDC59_RS02900 303daf5868088947d60c33e5f0e085b3 267 SUPERFAMILY SSF51366 1 266 2.35E-87 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CDC59_RS02900 303daf5868088947d60c33e5f0e085b3 267 Pfam PF00218 Indole-3-glycerol phosphate synthase 5 264 8.8E-96 T 29-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 CDC59_RS02900 303daf5868088947d60c33e5f0e085b3 267 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 3 267 35.797 T 29-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 CDC59_RS03265 50a4b69fd46c5e9757f10fa9143029a8 210 Pfam PF08750 CNP1-like family 43 199 4.3E-49 T 29-03-2018 IPR014861 Uncharacterised domain CNP1 CDC59_RS05150 f61e36153df6efcf3d0fefa57734ab03 206 Gene3D G3DSA:3.40.30.10 1 99 4.2E-22 T 29-03-2018 CDC59_RS05150 f61e36153df6efcf3d0fefa57734ab03 206 Pfam PF00043 Glutathione S-transferase, C-terminal domain 104 189 3.3E-16 T 29-03-2018 IPR004046 Glutathione S-transferase, C-terminal CDC59_RS05150 f61e36153df6efcf3d0fefa57734ab03 206 SUPERFAMILY SSF52833 1 78 4.44E-19 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS05150 f61e36153df6efcf3d0fefa57734ab03 206 Pfam PF02798 Glutathione S-transferase, N-terminal domain 1 74 2.0E-10 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CDC59_RS05150 f61e36153df6efcf3d0fefa57734ab03 206 Gene3D G3DSA:1.20.1050.10 100 205 1.7E-24 T 29-03-2018 CDC59_RS05150 f61e36153df6efcf3d0fefa57734ab03 206 SUPERFAMILY SSF47616 81 198 1.67E-29 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like CDC59_RS20325 0b5ccded5b8ba12513d58a01f1672876 762 SMART SM00560 616 754 0.0067 T 29-03-2018 IPR006558 LamG-like jellyroll fold CDC59_RS20325 0b5ccded5b8ba12513d58a01f1672876 762 SUPERFAMILY SSF49265 457 555 4.04E-8 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 CDC59_RS20325 0b5ccded5b8ba12513d58a01f1672876 762 Pfam PF05426 Alginate lyase 138 368 8.2E-17 T 29-03-2018 IPR008397 Alginate lyase domain GO:0016829|GO:0042597 KEGG: 00051+4.2.2.3|MetaCyc: PWY-6986 CDC59_RS20325 0b5ccded5b8ba12513d58a01f1672876 762 SUPERFAMILY SSF49899 559 761 7.27E-38 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CDC59_RS20325 0b5ccded5b8ba12513d58a01f1672876 762 Gene3D G3DSA:1.50.10.100 76 443 9.3E-84 T 29-03-2018 CDC59_RS20325 0b5ccded5b8ba12513d58a01f1672876 762 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 600 757 1.5E-32 T 29-03-2018 CDC59_RS20325 0b5ccded5b8ba12513d58a01f1672876 762 Gene3D G3DSA:2.60.40.10 463 559 1.4E-8 T 29-03-2018 IPR013783 Immunoglobulin-like fold CDC59_RS20325 0b5ccded5b8ba12513d58a01f1672876 762 SUPERFAMILY SSF48230 89 443 3.75E-61 T 29-03-2018 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 CDC59_RS20325 0b5ccded5b8ba12513d58a01f1672876 762 Gene3D G3DSA:2.60.120.200 560 762 2.3E-42 T 29-03-2018 CDC59_RS08685 78c15549c4af6483639b8ed8b6ad1407 463 Pfam PF03796 DnaB-like helicase C terminal domain 195 451 2.5E-115 T 29-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 CDC59_RS08685 78c15549c4af6483639b8ed8b6ad1407 463 Gene3D G3DSA:1.10.860.10 5 157 8.1E-46 T 29-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal CDC59_RS08685 78c15549c4af6483639b8ed8b6ad1407 463 Pfam PF00772 DnaB-like helicase N terminal domain 15 116 3.3E-34 T 29-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CDC59_RS08685 78c15549c4af6483639b8ed8b6ad1407 463 SUPERFAMILY SSF48024 13 124 9.15E-36 T 29-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CDC59_RS08685 78c15549c4af6483639b8ed8b6ad1407 463 SUPERFAMILY SSF52540 193 445 1.57E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS08685 78c15549c4af6483639b8ed8b6ad1407 463 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 15 453 2.5E-177 T 29-03-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 CDC59_RS08685 78c15549c4af6483639b8ed8b6ad1407 463 Gene3D G3DSA:3.40.50.300 175 458 7.5E-67 T 29-03-2018 CDC59_RS17635 5cde9be944f37c35a04d0528723da3f3 493 TIGRFAM TIGR01717 AMP-nucleosdse: AMP nucleosidase 24 493 1.0E-196 T 29-03-2018 IPR011271 AMP nucleosidase GO:0008714|GO:0009116|GO:0044209 KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 CDC59_RS17635 5cde9be944f37c35a04d0528723da3f3 493 Hamap MF_01932 AMP nucleosidase [amn]. 15 493 59.572 T 29-03-2018 IPR011271 AMP nucleosidase GO:0008714|GO:0009116|GO:0044209 KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 CDC59_RS17635 5cde9be944f37c35a04d0528723da3f3 493 Pfam PF01048 Phosphorylase superfamily 281 438 1.8E-15 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CDC59_RS17635 5cde9be944f37c35a04d0528723da3f3 493 Gene3D G3DSA:3.30.1730.10 18 177 5.8E-51 T 29-03-2018 IPR018953 AMP nucleoside phosphorylase, N-terminal KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 CDC59_RS17635 5cde9be944f37c35a04d0528723da3f3 493 SUPERFAMILY SSF53167 20 493 6.98E-150 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CDC59_RS17635 5cde9be944f37c35a04d0528723da3f3 493 Gene3D G3DSA:3.40.50.1580 183 475 1.2E-61 T 29-03-2018 CDC59_RS17635 5cde9be944f37c35a04d0528723da3f3 493 Pfam PF10423 Bacterial AMP nucleoside phosphorylase N-terminus 25 176 3.6E-47 T 29-03-2018 IPR018953 AMP nucleoside phosphorylase, N-terminal KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 CDC59_RS11435 d630a464475659abcc452697e54c1c58 367 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 1 365 31.506 T 29-03-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CDC59_RS11435 d630a464475659abcc452697e54c1c58 367 PIRSF PIRSF000148 1 367 5.7E-63 T 29-03-2018 CDC59_RS11435 d630a464475659abcc452697e54c1c58 367 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 144 351 9.4E-48 T 29-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CDC59_RS11435 d630a464475659abcc452697e54c1c58 367 SMART SM00859 2 121 3.1E-25 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CDC59_RS11435 d630a464475659abcc452697e54c1c58 367 SUPERFAMILY SSF51735 1 146 3.71E-51 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS11435 d630a464475659abcc452697e54c1c58 367 SUPERFAMILY SSF55347 133 352 4.82E-69 T 29-03-2018 CDC59_RS11435 d630a464475659abcc452697e54c1c58 367 Gene3D G3DSA:3.40.50.720 1 144 1.1E-23 T 29-03-2018 CDC59_RS11435 d630a464475659abcc452697e54c1c58 367 TIGRFAM TIGR01745 asd_gamma: aspartate-semialdehyde dehydrogenase 1 365 4.9E-219 T 29-03-2018 IPR011534 Aspartate-semialdehyde dehydrogenase, gamma-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CDC59_RS11435 d630a464475659abcc452697e54c1c58 367 Gene3D G3DSA:3.30.360.10 145 347 4.3E-54 T 29-03-2018 CDC59_RS11435 d630a464475659abcc452697e54c1c58 367 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 2 120 5.5E-25 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CDC59_RS11435 d630a464475659abcc452697e54c1c58 367 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 259 273 - T 29-03-2018 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CDC59_RS21195 103ddc5ee7edf4ac6158e9e6e3514327 534 Gene3D G3DSA:3.20.20.450 4 257 3.9E-79 T 29-03-2018 IPR001633 EAL domain CDC59_RS21195 103ddc5ee7edf4ac6158e9e6e3514327 534 SMART SM00086 468 510 2.6E-5 T 29-03-2018 IPR001610 PAC motif CDC59_RS21195 103ddc5ee7edf4ac6158e9e6e3514327 534 Gene3D G3DSA:3.30.450.20 391 533 2.0E-32 T 29-03-2018 CDC59_RS21195 103ddc5ee7edf4ac6158e9e6e3514327 534 Gene3D G3DSA:3.30.450.20 262 390 3.6E-21 T 29-03-2018 CDC59_RS21195 103ddc5ee7edf4ac6158e9e6e3514327 534 Pfam PF08447 PAS fold 433 503 2.9E-18 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 CDC59_RS21195 103ddc5ee7edf4ac6158e9e6e3514327 534 SUPERFAMILY SSF141868 10 253 7.85E-76 T 29-03-2018 IPR001633 EAL domain CDC59_RS21195 103ddc5ee7edf4ac6158e9e6e3514327 534 Pfam PF00563 EAL domain 10 241 7.0E-64 T 29-03-2018 IPR001633 EAL domain CDC59_RS21195 103ddc5ee7edf4ac6158e9e6e3514327 534 Pfam PF08448 PAS fold 281 387 5.7E-12 T 29-03-2018 IPR013656 PAS fold-4 CDC59_RS21195 103ddc5ee7edf4ac6158e9e6e3514327 534 SUPERFAMILY SSF55785 270 377 3.84E-9 T 29-03-2018 IPR000014 PAS domain CDC59_RS21195 103ddc5ee7edf4ac6158e9e6e3514327 534 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 393 516 7.5E-9 T 29-03-2018 IPR000014 PAS domain CDC59_RS21195 103ddc5ee7edf4ac6158e9e6e3514327 534 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 272 391 7.3E-7 T 29-03-2018 IPR000014 PAS domain CDC59_RS21195 103ddc5ee7edf4ac6158e9e6e3514327 534 SUPERFAMILY SSF55785 382 508 2.27E-22 T 29-03-2018 IPR000014 PAS domain CDC59_RS21195 103ddc5ee7edf4ac6158e9e6e3514327 534 SMART SM00052 4 246 1.6E-85 T 29-03-2018 IPR001633 EAL domain CDC59_RS21195 103ddc5ee7edf4ac6158e9e6e3514327 534 SMART SM00091 397 462 0.048 T 29-03-2018 IPR000014 PAS domain CDC59_RS21195 103ddc5ee7edf4ac6158e9e6e3514327 534 SMART SM00091 274 341 0.14 T 29-03-2018 IPR000014 PAS domain CDC59_RS06560 56c94f7683da9fc29f8ed137fa3e0a21 417 SUPERFAMILY SSF46626 313 413 6.45E-6 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS06560 56c94f7683da9fc29f8ed137fa3e0a21 417 Gene3D G3DSA:1.10.760.10 298 411 4.3E-4 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS06560 56c94f7683da9fc29f8ed137fa3e0a21 417 Pfam PF06181 Urate oxidase N-terminal 4 298 9.5E-143 T 29-03-2018 IPR010389 Urate oxidase N-terminal CDC59_RS14020 c4bb524394c65a91c2fae65168625672 449 Gene3D G3DSA:2.40.128.130 151 402 1.7E-9 T 29-03-2018 CDC59_RS05130 72b7f35837b7a5411efac2b54f49f8bb 210 PIRSF PIRSF006324 1 209 6.3E-48 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CDC59_RS05130 72b7f35837b7a5411efac2b54f49f8bb 210 Pfam PF01810 LysE type translocator 17 206 1.8E-31 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CDC59_RS04110 e4af148b4f88436b2a13f568e2006ee2 381 Gene3D G3DSA:2.60.260.20 212 260 8.1E-12 T 29-03-2018 CDC59_RS04110 e4af148b4f88436b2a13f568e2006ee2 381 Gene3D G3DSA:2.10.230.10 150 211 2.3E-21 T 29-03-2018 CDC59_RS04110 e4af148b4f88436b2a13f568e2006ee2 381 Gene3D G3DSA:1.10.287.110 1 116 5.2E-36 T 29-03-2018 IPR001623 DnaJ domain CDC59_RS04110 e4af148b4f88436b2a13f568e2006ee2 381 Gene3D G3DSA:2.60.260.20 261 372 1.3E-28 T 29-03-2018 CDC59_RS04110 e4af148b4f88436b2a13f568e2006ee2 381 Pfam PF00684 DnaJ central domain 153 213 1.2E-15 T 29-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CDC59_RS04110 e4af148b4f88436b2a13f568e2006ee2 381 PRINTS PR00625 DnaJ domain signature 62 81 6.3E-33 T 29-03-2018 IPR001623 DnaJ domain CDC59_RS04110 e4af148b4f88436b2a13f568e2006ee2 381 PRINTS PR00625 DnaJ domain signature 25 40 6.3E-33 T 29-03-2018 IPR001623 DnaJ domain CDC59_RS04110 e4af148b4f88436b2a13f568e2006ee2 381 PRINTS PR00625 DnaJ domain signature 7 25 6.3E-33 T 29-03-2018 IPR001623 DnaJ domain CDC59_RS04110 e4af148b4f88436b2a13f568e2006ee2 381 PRINTS PR00625 DnaJ domain signature 42 62 6.3E-33 T 29-03-2018 IPR001623 DnaJ domain CDC59_RS04110 e4af148b4f88436b2a13f568e2006ee2 381 Pfam PF00226 DnaJ domain 5 67 1.2E-27 T 29-03-2018 IPR001623 DnaJ domain CDC59_RS04110 e4af148b4f88436b2a13f568e2006ee2 381 ProSitePatterns PS00636 Nt-dnaJ domain signature. 47 66 - T 29-03-2018 IPR018253 DnaJ domain, conserved site CDC59_RS04110 e4af148b4f88436b2a13f568e2006ee2 381 SMART SM00271 4 62 3.8E-32 T 29-03-2018 IPR001623 DnaJ domain CDC59_RS04110 e4af148b4f88436b2a13f568e2006ee2 381 SUPERFAMILY SSF57938 140 216 2.09E-22 T 29-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CDC59_RS04110 e4af148b4f88436b2a13f568e2006ee2 381 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 5 355 2.5E-136 T 29-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 CDC59_RS04110 e4af148b4f88436b2a13f568e2006ee2 381 SUPERFAMILY SSF49493 264 350 1.57E-23 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CDC59_RS04110 e4af148b4f88436b2a13f568e2006ee2 381 Pfam PF01556 DnaJ C terminal domain 127 339 3.7E-41 T 29-03-2018 IPR002939 Chaperone DnaJ, C-terminal CDC59_RS04110 e4af148b4f88436b2a13f568e2006ee2 381 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 378 41.548 T 29-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 CDC59_RS04110 e4af148b4f88436b2a13f568e2006ee2 381 SUPERFAMILY SSF46565 1 109 7.72E-36 T 29-03-2018 IPR001623 DnaJ domain CDC59_RS04110 e4af148b4f88436b2a13f568e2006ee2 381 SUPERFAMILY SSF49493 121 161 7.46E-19 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CDC59_RS04110 e4af148b4f88436b2a13f568e2006ee2 381 SUPERFAMILY SSF49493 220 262 7.46E-19 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CDC59_RS01250 29241d41b8e5bbed9bf830dbe16e7817 232 Pfam PF00072 Response regulator receiver domain 15 126 1.8E-17 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS01250 29241d41b8e5bbed9bf830dbe16e7817 232 ProSitePatterns PS00622 LuxR-type HTH domain signature. 184 211 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS01250 29241d41b8e5bbed9bf830dbe16e7817 232 Gene3D G3DSA:1.10.10.10 145 227 2.3E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS01250 29241d41b8e5bbed9bf830dbe16e7817 232 SMART SM00448 13 126 4.3E-16 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS01250 29241d41b8e5bbed9bf830dbe16e7817 232 SMART SM00421 167 224 2.0E-16 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS01250 29241d41b8e5bbed9bf830dbe16e7817 232 Gene3D G3DSA:3.40.50.2300 12 144 1.3E-25 T 29-03-2018 CDC59_RS01250 29241d41b8e5bbed9bf830dbe16e7817 232 SUPERFAMILY SSF52172 13 143 1.99E-24 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS01250 29241d41b8e5bbed9bf830dbe16e7817 232 Pfam PF00196 Bacterial regulatory proteins, luxR family 170 222 9.7E-16 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS01250 29241d41b8e5bbed9bf830dbe16e7817 232 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 200 8.8E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS01250 29241d41b8e5bbed9bf830dbe16e7817 232 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 200 212 8.8E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS01250 29241d41b8e5bbed9bf830dbe16e7817 232 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 184 8.8E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS01250 29241d41b8e5bbed9bf830dbe16e7817 232 SUPERFAMILY SSF46894 161 230 2.24E-17 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CDC59_RS13325 4e175e90969160e7e65f93980c5a42b0 413 Gene3D G3DSA:3.30.470.20 210 407 6.6E-43 T 29-03-2018 CDC59_RS13325 4e175e90969160e7e65f93980c5a42b0 413 Pfam PF02222 ATP-grasp domain 143 310 8.6E-45 T 29-03-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type CDC59_RS13325 4e175e90969160e7e65f93980c5a42b0 413 Gene3D G3DSA:3.30.1490.20 148 209 2.3E-10 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CDC59_RS13325 4e175e90969160e7e65f93980c5a42b0 413 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 32 393 7.6E-108 T 29-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 CDC59_RS13325 4e175e90969160e7e65f93980c5a42b0 413 SUPERFAMILY SSF56059 129 330 2.98E-51 T 29-03-2018 CDC59_RS13325 4e175e90969160e7e65f93980c5a42b0 413 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 31 392 39.093 T 29-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 CDC59_RS13325 4e175e90969160e7e65f93980c5a42b0 413 SUPERFAMILY SSF51246 334 406 8.63E-16 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CDC59_RS13325 4e175e90969160e7e65f93980c5a42b0 413 SUPERFAMILY SSF52440 30 125 7.34E-27 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CDC59_RS13325 4e175e90969160e7e65f93980c5a42b0 413 Gene3D G3DSA:3.40.50.20 30 116 5.1E-23 T 29-03-2018 CDC59_RS13570 b624ac0eba6f4ee2e34ecb5fef8a304e 464 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 2 452 73.549 T 29-03-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 CDC59_RS13570 b624ac0eba6f4ee2e34ecb5fef8a304e 464 Pfam PF04055 Radical SAM superfamily 150 329 5.4E-29 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CDC59_RS13570 b624ac0eba6f4ee2e34ecb5fef8a304e 464 Gene3D G3DSA:3.80.30.20 143 385 9.4E-51 T 29-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe CDC59_RS13570 b624ac0eba6f4ee2e34ecb5fef8a304e 464 Pfam PF00919 Uncharacterized protein family UPF0004 3 103 3.0E-29 T 29-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 CDC59_RS13570 b624ac0eba6f4ee2e34ecb5fef8a304e 464 SUPERFAMILY SSF102114 124 375 4.71E-58 T 29-03-2018 CDC59_RS13570 b624ac0eba6f4ee2e34ecb5fef8a304e 464 SMART SM00729 146 371 6.1E-57 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CDC59_RS13570 b624ac0eba6f4ee2e34ecb5fef8a304e 464 Pfam PF01938 TRAM domain 384 450 1.2E-13 T 29-03-2018 IPR002792 TRAM domain CDC59_RS13570 b624ac0eba6f4ee2e34ecb5fef8a304e 464 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 3 450 2.4E-170 T 29-03-2018 CDC59_RS13570 b624ac0eba6f4ee2e34ecb5fef8a304e 464 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 3 448 8.4E-145 T 29-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 CDC59_RS13570 b624ac0eba6f4ee2e34ecb5fef8a304e 464 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 150 170 - T 29-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 CDC59_RS13410 97c4818a46a99c618bf0a198dea26329 577 Pfam PF11846 Virulence factor membrane-bound polymerase, C-terminal 376 539 1.7E-39 T 29-03-2018 IPR021797 Virulence factor membrane-bound polymerase, C-terminal CDC59_RS13410 97c4818a46a99c618bf0a198dea26329 577 Pfam PF15864 Protein glycosylation ligase 165 189 6.5E-10 T 29-03-2018 IPR031726 Protein glycosylation ligase domain CDC59_RS13410 97c4818a46a99c618bf0a198dea26329 577 Pfam PF04932 O-Antigen ligase 204 354 1.7E-13 T 29-03-2018 IPR007016 O-antigen ligase-related CDC59_RS11870 159693f9af56230d681873830e2a2672 215 Pfam PF02666 Phosphatidylserine decarboxylase 46 209 3.2E-32 T 29-03-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 CDC59_RS11870 159693f9af56230d681873830e2a2672 215 TIGRFAM TIGR00164 PS_decarb_rel: phosphatidylserine decarboxylase homolog 9 213 2.1E-69 T 29-03-2018 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 CDC59_RS11870 159693f9af56230d681873830e2a2672 215 Hamap MF_00664 Phosphatidylserine decarboxylase proenzyme [psd]. 9 215 38.468 T 29-03-2018 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 CDC59_RS11870 159693f9af56230d681873830e2a2672 215 Gene3D G3DSA:2.40.50.100 111 215 0.0064 T 29-03-2018 CDC59_RS11870 159693f9af56230d681873830e2a2672 215 Gene3D G3DSA:2.70.70.10 55 110 5.5E-5 T 29-03-2018 CDC59_RS06475 f9dc0068761d6070ad211f50c1459e38 187 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 146 162 - T 29-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 CDC59_RS06475 f9dc0068761d6070ad211f50c1459e38 187 TIGRFAM TIGR01461 greB: transcription elongation factor GreB 29 183 1.7E-66 T 29-03-2018 IPR006358 Transcription elongation factor GreB GO:0003677|GO:0032784 CDC59_RS06475 f9dc0068761d6070ad211f50c1459e38 187 PIRSF PIRSF006092 26 184 7.2E-43 T 29-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 CDC59_RS06475 f9dc0068761d6070ad211f50c1459e38 187 SUPERFAMILY SSF54534 108 182 1.57E-20 T 29-03-2018 CDC59_RS06475 f9dc0068761d6070ad211f50c1459e38 187 SUPERFAMILY SSF46557 29 103 1.11E-25 T 29-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CDC59_RS06475 f9dc0068761d6070ad211f50c1459e38 187 Hamap MF_00105 Transcription elongation factor GreA [greA]. 28 181 26.931 T 29-03-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 CDC59_RS06475 f9dc0068761d6070ad211f50c1459e38 187 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 43 74 - T 29-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 CDC59_RS06475 f9dc0068761d6070ad211f50c1459e38 187 Hamap MF_00930 Transcription elongation factor GreB [greB]. 27 183 49.891 T 29-03-2018 IPR006358 Transcription elongation factor GreB GO:0003677|GO:0032784 CDC59_RS06475 f9dc0068761d6070ad211f50c1459e38 187 Gene3D G3DSA:3.10.50.30 104 187 9.5E-25 T 29-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CDC59_RS06475 f9dc0068761d6070ad211f50c1459e38 187 Gene3D G3DSA:1.10.287.180 29 101 2.3E-27 T 29-03-2018 CDC59_RS06475 f9dc0068761d6070ad211f50c1459e38 187 Pfam PF03449 Transcription elongation factor, N-terminal 30 100 1.5E-24 T 29-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CDC59_RS06475 f9dc0068761d6070ad211f50c1459e38 187 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 109 182 3.1E-24 T 29-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CDC59_RS00415 7d29ca3b0073f3b86ea4e5502a5eb5c1 221 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 216 1.6E-18 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDC59_RS00415 7d29ca3b0073f3b86ea4e5502a5eb5c1 221 Pfam PF00072 Response regulator receiver domain 3 112 4.9E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS00415 7d29ca3b0073f3b86ea4e5502a5eb5c1 221 SMART SM00862 146 217 3.8E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDC59_RS00415 7d29ca3b0073f3b86ea4e5502a5eb5c1 221 Gene3D G3DSA:1.10.10.10 118 220 8.5E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS00415 7d29ca3b0073f3b86ea4e5502a5eb5c1 221 SUPERFAMILY SSF46894 118 216 1.13E-21 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CDC59_RS00415 7d29ca3b0073f3b86ea4e5502a5eb5c1 221 SUPERFAMILY SSF52172 1 131 4.27E-36 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS00415 7d29ca3b0073f3b86ea4e5502a5eb5c1 221 SMART SM00448 1 112 2.8E-35 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS00415 7d29ca3b0073f3b86ea4e5502a5eb5c1 221 Gene3D G3DSA:3.40.50.2300 1 117 6.0E-33 T 29-03-2018 CDC59_RS09615 1fd9026068babaf46629d158618ffbc5 290 PIRSF PIRSF009141 28 289 3.2E-97 T 29-03-2018 IPR008535 Protein of unknown function DUF817 CDC59_RS09615 1fd9026068babaf46629d158618ffbc5 290 Pfam PF05675 Protein of unknown function (DUF817) 39 275 4.1E-102 T 29-03-2018 IPR008535 Protein of unknown function DUF817 CDC59_RS06235 f67f57a0816d4fc3d7823818016e4cd5 592 Gene3D G3DSA:1.20.1560.10 7 337 1.6E-58 T 29-03-2018 CDC59_RS06235 f67f57a0816d4fc3d7823818016e4cd5 592 Pfam PF00005 ABC transporter 366 518 1.7E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS06235 f67f57a0816d4fc3d7823818016e4cd5 592 TIGRFAM TIGR02203 MsbA_lipidA: lipid A export permease/ATP-binding protein MsbA 19 590 6.7E-269 T 29-03-2018 IPR011917 ABC transporter, lipid A export, MsbA GO:0005524|GO:0016021|GO:0034040 CDC59_RS06235 f67f57a0816d4fc3d7823818016e4cd5 592 SUPERFAMILY SSF90123 17 335 4.84E-69 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CDC59_RS06235 f67f57a0816d4fc3d7823818016e4cd5 592 SMART SM00382 375 564 1.2E-20 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS06235 f67f57a0816d4fc3d7823818016e4cd5 592 ProSitePatterns PS00211 ABC transporters family signature. 490 504 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS06235 f67f57a0816d4fc3d7823818016e4cd5 592 Gene3D G3DSA:3.40.50.300 346 585 4.7E-78 T 29-03-2018 CDC59_RS06235 f67f57a0816d4fc3d7823818016e4cd5 592 Pfam PF00664 ABC transporter transmembrane region 35 305 1.9E-43 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CDC59_RS06235 f67f57a0816d4fc3d7823818016e4cd5 592 SUPERFAMILY SSF52540 340 589 7.73E-91 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS04660 9666c0523820953e1fea84fcb45a777e 613 Gene3D G3DSA:2.140.10.10 57 599 3.4E-10 T 29-03-2018 CDC59_RS04660 9666c0523820953e1fea84fcb45a777e 613 SUPERFAMILY SSF50998 288 303 9.68E-8 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CDC59_RS04660 9666c0523820953e1fea84fcb45a777e 613 SUPERFAMILY SSF50998 498 537 9.68E-8 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CDC59_RS04660 9666c0523820953e1fea84fcb45a777e 613 SUPERFAMILY SSF50998 82 105 9.68E-8 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CDC59_RS04660 9666c0523820953e1fea84fcb45a777e 613 SUPERFAMILY SSF50998 374 462 9.68E-8 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CDC59_RS04660 9666c0523820953e1fea84fcb45a777e 613 SUPERFAMILY SSF50998 183 217 9.68E-8 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CDC59_RS04660 9666c0523820953e1fea84fcb45a777e 613 Pfam PF05567 Neisseria PilC beta-propeller domain 173 389 1.3E-17 T 29-03-2018 IPR008707 PilC beta-propeller domain CDC59_RS10720 7b93912ceece68021a7a3bd84dce46ab 746 SMART SM00954 254 364 1.3E-65 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 CDC59_RS10720 7b93912ceece68021a7a3bd84dce46ab 746 SUPERFAMILY SSF109604 21 208 1.0E-41 T 29-03-2018 CDC59_RS10720 7b93912ceece68021a7a3bd84dce46ab 746 Pfam PF02824 TGS domain 418 477 2.0E-20 T 29-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 CDC59_RS10720 7b93912ceece68021a7a3bd84dce46ab 746 Gene3D G3DSA:3.30.460.10 211 344 3.7E-43 T 29-03-2018 CDC59_RS10720 7b93912ceece68021a7a3bd84dce46ab 746 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 34 744 8.8E-173 T 29-03-2018 IPR004811 RelA/SpoT family GO:0015969 CDC59_RS10720 7b93912ceece68021a7a3bd84dce46ab 746 Gene3D G3DSA:3.10.20.30 414 485 1.5E-20 T 29-03-2018 IPR012675 Beta-grasp domain CDC59_RS10720 7b93912ceece68021a7a3bd84dce46ab 746 Pfam PF13328 HD domain 28 195 2.2E-50 T 29-03-2018 IPR003607 HD/PDEase domain CDC59_RS10720 7b93912ceece68021a7a3bd84dce46ab 746 SUPERFAMILY SSF81271 409 477 3.49E-20 T 29-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CDC59_RS10720 7b93912ceece68021a7a3bd84dce46ab 746 SUPERFAMILY SSF55021 670 745 1.91E-13 T 29-03-2018 CDC59_RS10720 7b93912ceece68021a7a3bd84dce46ab 746 Pfam PF13291 ACT domain 670 745 1.3E-15 T 29-03-2018 IPR002912 ACT domain CDC59_RS10720 7b93912ceece68021a7a3bd84dce46ab 746 Gene3D G3DSA:3.30.70.260 669 746 2.1E-9 T 29-03-2018 CDC59_RS10720 7b93912ceece68021a7a3bd84dce46ab 746 Pfam PF04607 Region found in RelA / SpoT proteins 254 363 9.3E-38 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 CDC59_RS10720 7b93912ceece68021a7a3bd84dce46ab 746 SUPERFAMILY SSF81301 212 391 2.29E-62 T 29-03-2018 CDC59_RS00510 be78db26cb46a2372310411c89c85ed3 268 PIRSF PIRSF002854 1 268 1.2E-103 T 29-03-2018 IPR004872 Lipoprotein NlpA family CDC59_RS00510 be78db26cb46a2372310411c89c85ed3 268 TIGRFAM TIGR00363 TIGR00363: lipoprotein, YaeC family 14 266 2.8E-84 T 29-03-2018 IPR004872 Lipoprotein NlpA family CDC59_RS00510 be78db26cb46a2372310411c89c85ed3 268 Gene3D G3DSA:3.40.190.10 125 268 4.1E-54 T 29-03-2018 CDC59_RS00510 be78db26cb46a2372310411c89c85ed3 268 SUPERFAMILY SSF53850 30 268 4.75E-89 T 29-03-2018 CDC59_RS00510 be78db26cb46a2372310411c89c85ed3 268 Pfam PF03180 NLPA lipoprotein 30 268 5.0E-94 T 29-03-2018 IPR004872 Lipoprotein NlpA family CDC59_RS00510 be78db26cb46a2372310411c89c85ed3 268 Gene3D G3DSA:3.40.190.10 29 124 1.3E-25 T 29-03-2018 CDC59_RS19310 ae7bb1c269bdc000a4555ac7a4897ab9 379 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 40 364 5.3E-65 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 CDC59_RS19310 ae7bb1c269bdc000a4555ac7a4897ab9 379 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 54 266 2.1E-16 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CDC59_RS19310 ae7bb1c269bdc000a4555ac7a4897ab9 379 SUPERFAMILY SSF111369 55 258 5.62E-22 T 29-03-2018 CDC59_RS19310 ae7bb1c269bdc000a4555ac7a4897ab9 379 Gene3D G3DSA:1.20.1600.10 27 278 4.4E-27 T 29-03-2018 CDC59_RS07825 a7a4c53c3a9400c5c2e8ffc2b83860a3 632 SMART SM00283 266 513 1.0E-89 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CDC59_RS07825 a7a4c53c3a9400c5c2e8ffc2b83860a3 632 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 364 391 9.4E-56 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS07825 a7a4c53c3a9400c5c2e8ffc2b83860a3 632 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 441 470 9.4E-56 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS07825 a7a4c53c3a9400c5c2e8ffc2b83860a3 632 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 393 422 9.4E-56 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS07825 a7a4c53c3a9400c5c2e8ffc2b83860a3 632 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 287 316 9.4E-56 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS07825 a7a4c53c3a9400c5c2e8ffc2b83860a3 632 SUPERFAMILY SSF58104 241 514 2.35E-72 T 29-03-2018 CDC59_RS07825 a7a4c53c3a9400c5c2e8ffc2b83860a3 632 Pfam PF17200 Single Cache domain 2 37 184 2.4E-42 T 29-03-2018 IPR033480 Single Cache domain 2 CDC59_RS07825 a7a4c53c3a9400c5c2e8ffc2b83860a3 632 SMART SM01049 33 127 3.2E-36 T 29-03-2018 IPR033480 Single Cache domain 2 CDC59_RS07825 a7a4c53c3a9400c5c2e8ffc2b83860a3 632 Gene3D G3DSA:1.10.287.950 323 517 1.2E-50 T 29-03-2018 CDC59_RS07825 a7a4c53c3a9400c5c2e8ffc2b83860a3 632 Gene3D G3DSA:1.10.287.950 205 322 1.4E-15 T 29-03-2018 CDC59_RS07825 a7a4c53c3a9400c5c2e8ffc2b83860a3 632 Gene3D G3DSA:3.30.450.20 27 189 8.3E-44 T 29-03-2018 CDC59_RS07825 a7a4c53c3a9400c5c2e8ffc2b83860a3 632 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 325 480 1.8E-52 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CDC59_RS04850 110f2828c03494766efe2561fe81dd2b 397 Gene3D G3DSA:1.10.540.10 1 134 8.5E-38 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CDC59_RS04850 110f2828c03494766efe2561fe81dd2b 397 Gene3D G3DSA:2.40.110.10 135 230 8.8E-34 T 29-03-2018 CDC59_RS04850 110f2828c03494766efe2561fe81dd2b 397 SUPERFAMILY SSF47203 246 394 4.03E-41 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CDC59_RS04850 110f2828c03494766efe2561fe81dd2b 397 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 136 231 1.2E-21 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CDC59_RS04850 110f2828c03494766efe2561fe81dd2b 397 Gene3D G3DSA:1.20.140.10 231 395 6.3E-37 T 29-03-2018 CDC59_RS04850 110f2828c03494766efe2561fe81dd2b 397 SUPERFAMILY SSF56645 7 242 2.23E-79 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CDC59_RS04850 110f2828c03494766efe2561fe81dd2b 397 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 349 368 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CDC59_RS04850 110f2828c03494766efe2561fe81dd2b 397 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 20 132 5.7E-33 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CDC59_RS04850 110f2828c03494766efe2561fe81dd2b 397 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 244 389 4.4E-27 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CDC59_RS05490 b36b10d5d1622fd5a79a84ecc81af0d8 562 Gene3D G3DSA:2.40.50.140 100 180 1.3E-10 T 29-03-2018 CDC59_RS05490 b36b10d5d1622fd5a79a84ecc81af0d8 562 Gene3D G3DSA:2.40.50.140 185 269 1.1E-26 T 29-03-2018 CDC59_RS05490 b36b10d5d1622fd5a79a84ecc81af0d8 562 SUPERFAMILY SSF50249 345 443 7.09E-22 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDC59_RS05490 b36b10d5d1622fd5a79a84ecc81af0d8 562 Gene3D G3DSA:2.40.50.140 1 96 6.3E-9 T 29-03-2018 CDC59_RS05490 b36b10d5d1622fd5a79a84ecc81af0d8 562 SUPERFAMILY SSF50249 106 188 7.16E-16 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDC59_RS05490 b36b10d5d1622fd5a79a84ecc81af0d8 562 SUPERFAMILY SSF50249 192 280 2.76E-26 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDC59_RS05490 b36b10d5d1622fd5a79a84ecc81af0d8 562 Pfam PF00575 S1 RNA binding domain 22 88 4.1E-7 T 29-03-2018 IPR003029 S1 domain GO:0003676 CDC59_RS05490 b36b10d5d1622fd5a79a84ecc81af0d8 562 Pfam PF00575 S1 RNA binding domain 192 263 3.3E-22 T 29-03-2018 IPR003029 S1 domain GO:0003676 CDC59_RS05490 b36b10d5d1622fd5a79a84ecc81af0d8 562 Pfam PF00575 S1 RNA binding domain 279 350 4.4E-21 T 29-03-2018 IPR003029 S1 domain GO:0003676 CDC59_RS05490 b36b10d5d1622fd5a79a84ecc81af0d8 562 Pfam PF00575 S1 RNA binding domain 106 174 7.8E-13 T 29-03-2018 IPR003029 S1 domain GO:0003676 CDC59_RS05490 b36b10d5d1622fd5a79a84ecc81af0d8 562 Pfam PF00575 S1 RNA binding domain 453 523 1.4E-12 T 29-03-2018 IPR003029 S1 domain GO:0003676 CDC59_RS05490 b36b10d5d1622fd5a79a84ecc81af0d8 562 Pfam PF00575 S1 RNA binding domain 364 437 2.4E-19 T 29-03-2018 IPR003029 S1 domain GO:0003676 CDC59_RS05490 b36b10d5d1622fd5a79a84ecc81af0d8 562 PRINTS PR00681 Ribosomal protein S1 signature 87 106 2.2E-81 T 29-03-2018 CDC59_RS05490 b36b10d5d1622fd5a79a84ecc81af0d8 562 PRINTS PR00681 Ribosomal protein S1 signature 293 312 2.2E-81 T 29-03-2018 CDC59_RS05490 b36b10d5d1622fd5a79a84ecc81af0d8 562 PRINTS PR00681 Ribosomal protein S1 signature 111 127 2.2E-81 T 29-03-2018 CDC59_RS05490 b36b10d5d1622fd5a79a84ecc81af0d8 562 PRINTS PR00681 Ribosomal protein S1 signature 129 146 2.2E-81 T 29-03-2018 CDC59_RS05490 b36b10d5d1622fd5a79a84ecc81af0d8 562 PRINTS PR00681 Ribosomal protein S1 signature 215 236 2.2E-81 T 29-03-2018 CDC59_RS05490 b36b10d5d1622fd5a79a84ecc81af0d8 562 PRINTS PR00681 Ribosomal protein S1 signature 42 56 2.2E-81 T 29-03-2018 CDC59_RS05490 b36b10d5d1622fd5a79a84ecc81af0d8 562 PRINTS PR00681 Ribosomal protein S1 signature 333 351 2.2E-81 T 29-03-2018 CDC59_RS05490 b36b10d5d1622fd5a79a84ecc81af0d8 562 PRINTS PR00681 Ribosomal protein S1 signature 24 42 2.2E-81 T 29-03-2018 CDC59_RS05490 b36b10d5d1622fd5a79a84ecc81af0d8 562 PRINTS PR00681 Ribosomal protein S1 signature 158 178 2.2E-81 T 29-03-2018 CDC59_RS05490 b36b10d5d1622fd5a79a84ecc81af0d8 562 PIRSF PIRSF002111 1 537 1.0E-215 T 29-03-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 CDC59_RS05490 b36b10d5d1622fd5a79a84ecc81af0d8 562 SUPERFAMILY SSF50249 432 536 3.58E-20 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDC59_RS05490 b36b10d5d1622fd5a79a84ecc81af0d8 562 TIGRFAM TIGR00717 rpsA: ribosomal protein bS1 6 523 6.1E-205 T 29-03-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 CDC59_RS05490 b36b10d5d1622fd5a79a84ecc81af0d8 562 SUPERFAMILY SSF50249 7 116 4.55E-19 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDC59_RS05490 b36b10d5d1622fd5a79a84ecc81af0d8 562 Gene3D G3DSA:2.40.50.140 277 351 1.0E-25 T 29-03-2018 CDC59_RS05490 b36b10d5d1622fd5a79a84ecc81af0d8 562 SUPERFAMILY SSF50249 258 359 1.72E-26 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDC59_RS05490 b36b10d5d1622fd5a79a84ecc81af0d8 562 SMART SM00316 106 174 5.6E-10 T 29-03-2018 IPR022967 RNA-binding domain, S1 CDC59_RS05490 b36b10d5d1622fd5a79a84ecc81af0d8 562 SMART SM00316 452 523 1.3E-17 T 29-03-2018 IPR022967 RNA-binding domain, S1 CDC59_RS05490 b36b10d5d1622fd5a79a84ecc81af0d8 562 SMART SM00316 193 263 6.7E-29 T 29-03-2018 IPR022967 RNA-binding domain, S1 CDC59_RS05490 b36b10d5d1622fd5a79a84ecc81af0d8 562 SMART SM00316 365 437 1.0E-21 T 29-03-2018 IPR022967 RNA-binding domain, S1 CDC59_RS05490 b36b10d5d1622fd5a79a84ecc81af0d8 562 SMART SM00316 278 350 6.6E-25 T 29-03-2018 IPR022967 RNA-binding domain, S1 CDC59_RS05490 b36b10d5d1622fd5a79a84ecc81af0d8 562 SMART SM00316 22 90 8.4E-5 T 29-03-2018 IPR022967 RNA-binding domain, S1 CDC59_RS05490 b36b10d5d1622fd5a79a84ecc81af0d8 562 Gene3D G3DSA:2.40.50.140 362 443 1.3E-20 T 29-03-2018 CDC59_RS05490 b36b10d5d1622fd5a79a84ecc81af0d8 562 Gene3D G3DSA:2.40.50.140 451 532 2.6E-18 T 29-03-2018 CDC59_RS03375 0a484b69938219727dd3c2c287731b84 257 Pfam PF15984 Bacterial collagen, middle region 41 180 2.4E-8 T 29-03-2018 IPR031929 Bacterial collagen-like protein, middle domain CDC59_RS01970 5d328c3e9040787deabf0d5d06b3e66c 430 SMART SM00304 153 205 4.2E-5 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CDC59_RS01970 5d328c3e9040787deabf0d5d06b3e66c 430 PRINTS PR00344 Bacterial sensor protein C-terminal signature 388 406 9.2E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS01970 5d328c3e9040787deabf0d5d06b3e66c 430 PRINTS PR00344 Bacterial sensor protein C-terminal signature 353 367 9.2E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS01970 5d328c3e9040787deabf0d5d06b3e66c 430 PRINTS PR00344 Bacterial sensor protein C-terminal signature 371 381 9.2E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS01970 5d328c3e9040787deabf0d5d06b3e66c 430 PRINTS PR00344 Bacterial sensor protein C-terminal signature 412 425 9.2E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS01970 5d328c3e9040787deabf0d5d06b3e66c 430 Gene3D G3DSA:1.10.287.130 196 267 7.5E-11 T 29-03-2018 CDC59_RS01970 5d328c3e9040787deabf0d5d06b3e66c 430 Gene3D G3DSA:3.30.565.10 275 428 4.3E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS01970 5d328c3e9040787deabf0d5d06b3e66c 430 Pfam PF00512 His Kinase A (phospho-acceptor) domain 207 271 7.9E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS01970 5d328c3e9040787deabf0d5d06b3e66c 430 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 318 426 4.5E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS01970 5d328c3e9040787deabf0d5d06b3e66c 430 SMART SM00387 317 428 2.7E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS01970 5d328c3e9040787deabf0d5d06b3e66c 430 SUPERFAMILY SSF55874 261 426 5.89E-41 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS01970 5d328c3e9040787deabf0d5d06b3e66c 430 SUPERFAMILY SSF47384 189 271 6.08E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS01970 5d328c3e9040787deabf0d5d06b3e66c 430 SMART SM00388 206 271 5.4E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS07085 d0ed35f4002fc943426c3abb53cf107a 268 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 120 131 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CDC59_RS07085 d0ed35f4002fc943426c3abb53cf107a 268 Pfam PF14697 4Fe-4S dicluster domain 83 137 7.0E-17 T 29-03-2018 CDC59_RS07085 d0ed35f4002fc943426c3abb53cf107a 268 Pfam PF04060 Putative Fe-S cluster 16 48 4.8E-14 T 29-03-2018 IPR007202 4Fe-4S domain GO:0051536 CDC59_RS07085 d0ed35f4002fc943426c3abb53cf107a 268 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 90 101 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CDC59_RS07085 d0ed35f4002fc943426c3abb53cf107a 268 SUPERFAMILY SSF54862 10 144 9.77E-32 T 29-03-2018 CDC59_RS07085 d0ed35f4002fc943426c3abb53cf107a 268 Gene3D G3DSA:3.30.70.20 126 227 2.3E-5 T 29-03-2018 CDC59_RS07085 d0ed35f4002fc943426c3abb53cf107a 268 Gene3D G3DSA:3.30.70.20 95 125 9.8E-13 T 29-03-2018 CDC59_RS07085 d0ed35f4002fc943426c3abb53cf107a 268 Gene3D G3DSA:3.30.70.20 14 94 5.1E-9 T 29-03-2018 CDC59_RS07085 d0ed35f4002fc943426c3abb53cf107a 268 TIGRFAM TIGR01944 rnfB: electron transport complex, RnfABCDGE type, B subunit 6 156 1.6E-69 T 29-03-2018 IPR010207 Electron transport complex, RnfB/RsxB GO:0009055|GO:0051536 CDC59_RS06550 c86b37d396e7ca68b6bd44599ed70205 252 Gene3D G3DSA:1.10.10.10 11 88 8.0E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS06550 c86b37d396e7ca68b6bd44599ed70205 252 SUPERFAMILY SSF46785 27 96 6.82E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS06550 c86b37d396e7ca68b6bd44599ed70205 252 SMART SM00895 102 226 4.1E-17 T 29-03-2018 IPR011711 GntR, C-terminal CDC59_RS06550 c86b37d396e7ca68b6bd44599ed70205 252 SMART SM00345 34 92 6.7E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDC59_RS06550 c86b37d396e7ca68b6bd44599ed70205 252 Pfam PF00392 Bacterial regulatory proteins, gntR family 32 92 8.4E-12 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDC59_RS06550 c86b37d396e7ca68b6bd44599ed70205 252 Pfam PF07729 FCD domain 103 225 5.7E-23 T 29-03-2018 IPR011711 GntR, C-terminal CDC59_RS06550 c86b37d396e7ca68b6bd44599ed70205 252 Gene3D G3DSA:1.20.120.530 89 240 4.8E-27 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CDC59_RS06550 c86b37d396e7ca68b6bd44599ed70205 252 SUPERFAMILY SSF48008 98 232 2.38E-25 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CDC59_RS02615 f9e5f8fc5e2431943ee168ab30143d59 124 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 5 99 3.5E-27 T 29-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 CDC59_RS02615 f9e5f8fc5e2431943ee168ab30143d59 124 SUPERFAMILY SSF101386 4 103 3.18E-22 T 29-03-2018 CDC59_RS02615 f9e5f8fc5e2431943ee168ab30143d59 124 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 22 102 1.1E-13 T 29-03-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 CDC59_RS02615 f9e5f8fc5e2431943ee168ab30143d59 124 Gene3D G3DSA:1.10.287.1080 1 104 2.4E-21 T 29-03-2018 CDC59_RS02615 f9e5f8fc5e2431943ee168ab30143d59 124 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 2 99 21.884 T 29-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 CDC59_RS12975 dcf570c733dfb501a29808e3d33ccf1b 383 SUPERFAMILY SSF54862 198 346 1.72E-18 T 29-03-2018 CDC59_RS12975 dcf570c733dfb501a29808e3d33ccf1b 383 Gene3D G3DSA:3.30.70.20 229 332 5.0E-12 T 29-03-2018 CDC59_RS12975 dcf570c733dfb501a29808e3d33ccf1b 383 Gene3D G3DSA:3.30.70.20 144 228 4.7E-5 T 29-03-2018 CDC59_RS12975 dcf570c733dfb501a29808e3d33ccf1b 383 Pfam PF13484 4Fe-4S double cluster binding domain 220 284 1.6E-21 T 29-03-2018 CDC59_RS12975 dcf570c733dfb501a29808e3d33ccf1b 383 Gene3D G3DSA:1.25.40.290 333 383 6.2E-4 T 29-03-2018 CDC59_RS12975 dcf570c733dfb501a29808e3d33ccf1b 383 Hamap MF_00916 Epoxyqueuosine reductase [queG]. 24 343 46.879 T 29-03-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 CDC59_RS12975 dcf570c733dfb501a29808e3d33ccf1b 383 Pfam PF08331 Domain of unknown function (DUF1730) 79 168 3.5E-19 T 29-03-2018 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700 CDC59_RS12975 dcf570c733dfb501a29808e3d33ccf1b 383 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 221 232 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CDC59_RS12975 dcf570c733dfb501a29808e3d33ccf1b 383 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 31 383 3.2E-133 T 29-03-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 CDC59_RS01990 880f7230f6918d76cd9970e66d8adc60 429 Pfam PF00083 Sugar (and other) transporter 17 422 2.0E-28 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CDC59_RS01990 880f7230f6918d76cd9970e66d8adc60 429 Gene3D G3DSA:1.20.1250.20 10 223 1.9E-23 T 29-03-2018 CDC59_RS01990 880f7230f6918d76cd9970e66d8adc60 429 Gene3D G3DSA:1.20.1250.20 228 427 3.1E-20 T 29-03-2018 CDC59_RS01990 880f7230f6918d76cd9970e66d8adc60 429 SUPERFAMILY SSF103473 10 423 3.66E-66 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS01990 880f7230f6918d76cd9970e66d8adc60 429 ProSitePatterns PS00217 Sugar transport proteins signature 2. 123 148 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CDC59_RS09510 b10a1c21b3700c9495a726a7a53c140c 318 SUPERFAMILY SSF46785 5 112 2.45E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS09510 b10a1c21b3700c9495a726a7a53c140c 318 SUPERFAMILY SSF53850 90 297 3.8E-36 T 29-03-2018 CDC59_RS09510 b10a1c21b3700c9495a726a7a53c140c 318 Gene3D G3DSA:3.40.190.10 180 265 1.1E-18 T 29-03-2018 CDC59_RS09510 b10a1c21b3700c9495a726a7a53c140c 318 Gene3D G3DSA:3.40.190.10 88 179 5.1E-13 T 29-03-2018 CDC59_RS09510 b10a1c21b3700c9495a726a7a53c140c 318 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 1.3E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS09510 b10a1c21b3700c9495a726a7a53c140c 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 4.3E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS09510 b10a1c21b3700c9495a726a7a53c140c 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 4.3E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS09510 b10a1c21b3700c9495a726a7a53c140c 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 4.3E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS09510 b10a1c21b3700c9495a726a7a53c140c 318 Gene3D G3DSA:1.10.10.10 1 86 4.1E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS09510 b10a1c21b3700c9495a726a7a53c140c 318 Pfam PF03466 LysR substrate binding domain 90 293 4.2E-34 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS06755 4ebee6ee0376a197c016d51b97bb5b3e 318 SUPERFAMILY SSF50249 21 78 4.2E-7 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDC59_RS06755 4ebee6ee0376a197c016d51b97bb5b3e 318 Pfam PF03193 RsgA GTPase 74 251 1.8E-50 T 29-03-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 CDC59_RS06755 4ebee6ee0376a197c016d51b97bb5b3e 318 Gene3D G3DSA:1.10.40.50 253 318 2.4E-19 T 29-03-2018 CDC59_RS06755 4ebee6ee0376a197c016d51b97bb5b3e 318 Gene3D G3DSA:2.40.50.140 16 76 2.9E-15 T 29-03-2018 CDC59_RS06755 4ebee6ee0376a197c016d51b97bb5b3e 318 Gene3D G3DSA:3.40.50.300 88 251 3.8E-15 T 29-03-2018 CDC59_RS06755 4ebee6ee0376a197c016d51b97bb5b3e 318 SUPERFAMILY SSF52540 90 316 1.08E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS06755 4ebee6ee0376a197c016d51b97bb5b3e 318 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 55 309 8.2E-63 T 29-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 CDC59_RS06755 4ebee6ee0376a197c016d51b97bb5b3e 318 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 20 316 34.946 T 29-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 CDC59_RS09455 461bab8969f05a719833dd5c9d021f74 513 SUPERFAMILY SSF58104 231 512 5.62E-75 T 29-03-2018 CDC59_RS09455 461bab8969f05a719833dd5c9d021f74 513 Pfam PF00672 HAMP domain 211 259 4.3E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CDC59_RS09455 461bab8969f05a719833dd5c9d021f74 513 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 322 478 1.8E-53 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CDC59_RS09455 461bab8969f05a719833dd5c9d021f74 513 SUPERFAMILY SSF47170 47 146 5.62E-9 T 29-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 CDC59_RS09455 461bab8969f05a719833dd5c9d021f74 513 Gene3D G3DSA:1.10.287.950 323 513 5.1E-48 T 29-03-2018 CDC59_RS09455 461bab8969f05a719833dd5c9d021f74 513 Gene3D G3DSA:1.10.287.1060 240 322 0.0045 T 29-03-2018 CDC59_RS09455 461bab8969f05a719833dd5c9d021f74 513 Pfam PF02203 Tar ligand binding domain homologue 1 170 2.9E-45 T 29-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 CDC59_RS09455 461bab8969f05a719833dd5c9d021f74 513 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 5 30 1.9E-62 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS09455 461bab8969f05a719833dd5c9d021f74 513 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 439 468 1.9E-62 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS09455 461bab8969f05a719833dd5c9d021f74 513 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 391 420 1.9E-62 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS09455 461bab8969f05a719833dd5c9d021f74 513 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 285 314 1.9E-62 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS09455 461bab8969f05a719833dd5c9d021f74 513 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 362 389 1.9E-62 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS09455 461bab8969f05a719833dd5c9d021f74 513 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 187 207 1.9E-62 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS09455 461bab8969f05a719833dd5c9d021f74 513 SMART SM00283 264 511 6.8E-87 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CDC59_RS09455 461bab8969f05a719833dd5c9d021f74 513 SMART SM00304 211 263 3.6E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CDC59_RS09455 461bab8969f05a719833dd5c9d021f74 513 Gene3D G3DSA:1.20.120.30 23 185 6.5E-29 T 29-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain CDC59_RS16680 f33f21c3c90b1f588a0805af9ca4bc0a 432 Gene3D G3DSA:1.25.10.10 33 215 1.8E-16 T 29-03-2018 IPR011989 Armadillo-like helical CDC59_RS16680 f33f21c3c90b1f588a0805af9ca4bc0a 432 SUPERFAMILY SSF48371 60 214 4.53E-16 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 CDC59_RS16680 f33f21c3c90b1f588a0805af9ca4bc0a 432 Pfam PF13646 HEAT repeats 158 226 2.2E-12 T 29-03-2018 CDC59_RS18100 984486c2f232623ccda85572ef996c77 75 Gene3D G3DSA:1.10.10.10 11 65 1.3E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS06075 862444fce2c2f8dac3a12fbff6e91c46 329 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 135 308 3.7E-43 T 29-03-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG CDC59_RS06075 862444fce2c2f8dac3a12fbff6e91c46 329 SUPERFAMILY SSF102405 110 307 3.82E-57 T 29-03-2018 CDC59_RS06075 862444fce2c2f8dac3a12fbff6e91c46 329 Pfam PF03641 Possible lysine decarboxylase 177 306 2.5E-31 T 29-03-2018 IPR031100 LOG family CDC59_RS06075 862444fce2c2f8dac3a12fbff6e91c46 329 Gene3D G3DSA:3.40.50.450 111 326 3.2E-65 T 29-03-2018 CDC59_RS00540 9eb7266aedad7df9c709c9fc1f7ec1d3 271 Pfam PF09694 Bacterial protein of unknown function (Gcw_chp) 43 271 8.3E-69 T 29-03-2018 IPR010239 Conserved hypothetical protein CHP02001 CDC59_RS00540 9eb7266aedad7df9c709c9fc1f7ec1d3 271 TIGRFAM TIGR02001 gcw_chp: conserved hypothetical protein 23 271 1.1E-81 T 29-03-2018 IPR010239 Conserved hypothetical protein CHP02001 CDC59_RS17585 f16d64b18b5832416f73f16d0c2569d9 1522 Pfam PF00668 Condensation domain 1074 1505 3.3E-58 T 29-03-2018 IPR001242 Condensation domain CDC59_RS17585 f16d64b18b5832416f73f16d0c2569d9 1522 SMART SM00823 Phosphopantetheine attachment site 987 1056 6.6E-4 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CDC59_RS17585 f16d64b18b5832416f73f16d0c2569d9 1522 SUPERFAMILY SSF47336 979 1053 8.51E-18 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS17585 f16d64b18b5832416f73f16d0c2569d9 1522 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 448 560 3.9E-18 T 29-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CDC59_RS17585 f16d64b18b5832416f73f16d0c2569d9 1522 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1011 1026 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CDC59_RS17585 f16d64b18b5832416f73f16d0c2569d9 1522 SUPERFAMILY SSF53901 473 493 2.43E-79 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS17585 f16d64b18b5832416f73f16d0c2569d9 1522 SUPERFAMILY SSF53901 216 440 2.43E-79 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS17585 f16d64b18b5832416f73f16d0c2569d9 1522 SUPERFAMILY SSF53901 70 186 2.43E-79 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS17585 f16d64b18b5832416f73f16d0c2569d9 1522 Gene3D G3DSA:1.10.1200.10 959 1057 3.0E-20 T 29-03-2018 CDC59_RS17585 f16d64b18b5832416f73f16d0c2569d9 1522 Gene3D G3DSA:3.30.559.10 1058 1279 4.7E-26 T 29-03-2018 CDC59_RS17585 f16d64b18b5832416f73f16d0c2569d9 1522 Gene3D G3DSA:3.30.70.250 738 779 4.6E-18 T 29-03-2018 CDC59_RS17585 f16d64b18b5832416f73f16d0c2569d9 1522 Gene3D G3DSA:3.40.366.10 593 737 1.7E-41 T 29-03-2018 CDC59_RS17585 f16d64b18b5832416f73f16d0c2569d9 1522 Pfam PF00550 Phosphopantetheine attachment site 990 1052 5.1E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS17585 f16d64b18b5832416f73f16d0c2569d9 1522 Pfam PF00698 Acyl transferase domain 595 887 1.3E-47 T 29-03-2018 IPR014043 Acyl transferase CDC59_RS17585 f16d64b18b5832416f73f16d0c2569d9 1522 Gene3D G3DSA:3.40.47.10 62 329 2.7E-65 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS17585 f16d64b18b5832416f73f16d0c2569d9 1522 SUPERFAMILY SSF52151 593 729 5.23E-64 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CDC59_RS17585 f16d64b18b5832416f73f16d0c2569d9 1522 SUPERFAMILY SSF52151 789 886 5.23E-64 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CDC59_RS17585 f16d64b18b5832416f73f16d0c2569d9 1522 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 71 317 1.5E-65 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CDC59_RS17585 f16d64b18b5832416f73f16d0c2569d9 1522 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 325 444 4.9E-39 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CDC59_RS17585 f16d64b18b5832416f73f16d0c2569d9 1522 SMART SM00825 Beta-ketoacyl synthase 72 497 5.1E-164 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CDC59_RS17585 f16d64b18b5832416f73f16d0c2569d9 1522 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 233 249 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site CDC59_RS17585 f16d64b18b5832416f73f16d0c2569d9 1522 SUPERFAMILY SSF52777 1264 1501 3.72E-42 T 29-03-2018 CDC59_RS17585 f16d64b18b5832416f73f16d0c2569d9 1522 Gene3D G3DSA:3.40.47.10 333 499 9.5E-54 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS17585 f16d64b18b5832416f73f16d0c2569d9 1522 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 597 896 3.7E-99 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CDC59_RS17585 f16d64b18b5832416f73f16d0c2569d9 1522 SUPERFAMILY SSF52777 1078 1255 8.78E-33 T 29-03-2018 CDC59_RS17585 f16d64b18b5832416f73f16d0c2569d9 1522 Gene3D G3DSA:3.40.366.10 780 903 2.1E-26 T 29-03-2018 CDC59_RS17585 f16d64b18b5832416f73f16d0c2569d9 1522 SUPERFAMILY SSF55048 727 788 4.71E-9 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CDC59_RS06110 48681179463caf0f6eb4fdd4ce6725f1 365 Gene3D G3DSA:3.90.380.10 125 365 3.7E-32 T 29-03-2018 CDC59_RS06110 48681179463caf0f6eb4fdd4ce6725f1 365 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 24 49 2.3E-8 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CDC59_RS06110 48681179463caf0f6eb4fdd4ce6725f1 365 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 54 69 2.3E-8 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CDC59_RS06110 48681179463caf0f6eb4fdd4ce6725f1 365 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 94 114 2.3E-8 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CDC59_RS06110 48681179463caf0f6eb4fdd4ce6725f1 365 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 167 364 6.0E-35 T 29-03-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 CDC59_RS06110 48681179463caf0f6eb4fdd4ce6725f1 365 Pfam PF00355 Rieske [2Fe-2S] domain 43 121 2.6E-11 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CDC59_RS06110 48681179463caf0f6eb4fdd4ce6725f1 365 SUPERFAMILY SSF50022 4 140 4.19E-33 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CDC59_RS06110 48681179463caf0f6eb4fdd4ce6725f1 365 SUPERFAMILY SSF55961 160 363 1.81E-43 T 29-03-2018 CDC59_RS06110 48681179463caf0f6eb4fdd4ce6725f1 365 Gene3D G3DSA:2.20.25.10 79 124 1.3E-17 T 29-03-2018 CDC59_RS09155 5f9d38d81287fb4214daeaa55e4535ed 292 SUPERFAMILY SSF54713 56 145 1.7E-26 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CDC59_RS09155 5f9d38d81287fb4214daeaa55e4535ed 292 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 285 1.1E-90 T 29-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CDC59_RS09155 5f9d38d81287fb4214daeaa55e4535ed 292 Gene3D G3DSA:3.30.479.20 58 153 3.2E-25 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CDC59_RS09155 5f9d38d81287fb4214daeaa55e4535ed 292 Gene3D G3DSA:1.10.8.10 1 56 3.4E-16 T 29-03-2018 CDC59_RS09155 5f9d38d81287fb4214daeaa55e4535ed 292 ProSitePatterns PS01127 Elongation factor Ts signature 2. 75 85 - T 29-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CDC59_RS09155 5f9d38d81287fb4214daeaa55e4535ed 292 SUPERFAMILY SSF54713 149 285 7.27E-49 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CDC59_RS09155 5f9d38d81287fb4214daeaa55e4535ed 292 Gene3D G3DSA:3.30.479.20 154 284 5.4E-48 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CDC59_RS09155 5f9d38d81287fb4214daeaa55e4535ed 292 Pfam PF00889 Elongation factor TS 71 268 6.2E-69 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CDC59_RS09155 5f9d38d81287fb4214daeaa55e4535ed 292 SUPERFAMILY SSF46934 3 56 2.42E-12 T 29-03-2018 IPR009060 UBA-like GO:0005515 CDC59_RS09155 5f9d38d81287fb4214daeaa55e4535ed 292 Hamap MF_00050 Elongation factor Ts [tsf]. 1 285 79.604 T 29-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CDC59_RS04815 4b6a442eaf73a4be177972e5ffc27499 229 SMART SM00382 28 217 2.5E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS04815 4b6a442eaf73a4be177972e5ffc27499 229 Gene3D G3DSA:3.40.50.300 5 225 6.8E-47 T 29-03-2018 CDC59_RS04815 4b6a442eaf73a4be177972e5ffc27499 229 Pfam PF00005 ABC transporter 20 166 5.4E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS04815 4b6a442eaf73a4be177972e5ffc27499 229 SUPERFAMILY SSF52540 16 219 5.89E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS04385 2bc000684f0668f9dafe762e690d7630 433 Gene3D G3DSA:3.40.640.10 173 320 2.5E-42 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDC59_RS04385 2bc000684f0668f9dafe762e690d7630 433 Pfam PF00202 Aminotransferase class-III 35 403 6.8E-76 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CDC59_RS04385 2bc000684f0668f9dafe762e690d7630 433 SUPERFAMILY SSF53383 5 432 2.28E-125 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS04385 2bc000684f0668f9dafe762e690d7630 433 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 242 278 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CDC59_RS04385 2bc000684f0668f9dafe762e690d7630 433 Gene3D G3DSA:3.90.1150.10 321 433 3.8E-15 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS04385 2bc000684f0668f9dafe762e690d7630 433 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 6 433 101.998 T 29-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 CDC59_RS04385 2bc000684f0668f9dafe762e690d7630 433 Gene3D G3DSA:3.90.1150.10 2 172 7.4E-44 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS04385 2bc000684f0668f9dafe762e690d7630 433 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 7 432 2.0E-182 T 29-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 CDC59_RS01370 18996a99a1b835b29cd42f0e78796198 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 2.4E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS01370 18996a99a1b835b29cd42f0e78796198 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 2.4E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS01370 18996a99a1b835b29cd42f0e78796198 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 2.4E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS01370 18996a99a1b835b29cd42f0e78796198 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 69 8.6E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS01370 18996a99a1b835b29cd42f0e78796198 307 SUPERFAMILY SSF46785 6 86 7.88E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS01370 18996a99a1b835b29cd42f0e78796198 307 Gene3D G3DSA:3.40.190.10 97 181 5.0E-17 T 29-03-2018 CDC59_RS01370 18996a99a1b835b29cd42f0e78796198 307 SUPERFAMILY SSF53850 98 300 4.89E-35 T 29-03-2018 CDC59_RS01370 18996a99a1b835b29cd42f0e78796198 307 Gene3D G3DSA:3.40.190.10 182 267 3.5E-15 T 29-03-2018 CDC59_RS01370 18996a99a1b835b29cd42f0e78796198 307 Pfam PF03466 LysR substrate binding domain 98 298 2.1E-30 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS01370 18996a99a1b835b29cd42f0e78796198 307 Gene3D G3DSA:1.10.10.10 6 90 2.0E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS09200 7ca4d225aef809701aa0335134f2b077 356 Gene3D G3DSA:2.160.10.10 202 356 8.9E-23 T 29-03-2018 CDC59_RS09200 7ca4d225aef809701aa0335134f2b077 356 Hamap MF_00523 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase [lpxD]. 8 338 36.349 T 29-03-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 CDC59_RS09200 7ca4d225aef809701aa0335134f2b077 356 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 234 268 4.2E-7 T 29-03-2018 IPR001451 Hexapeptide repeat CDC59_RS09200 7ca4d225aef809701aa0335134f2b077 356 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 154 187 3.1E-8 T 29-03-2018 IPR001451 Hexapeptide repeat CDC59_RS09200 7ca4d225aef809701aa0335134f2b077 356 TIGRFAM TIGR01853 lipid_A_lpxD: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD 7 341 3.0E-107 T 29-03-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 CDC59_RS09200 7ca4d225aef809701aa0335134f2b077 356 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 271 305 0.2 T 29-03-2018 IPR001451 Hexapeptide repeat CDC59_RS09200 7ca4d225aef809701aa0335134f2b077 356 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 124 152 0.2 T 29-03-2018 IPR001451 Hexapeptide repeat CDC59_RS09200 7ca4d225aef809701aa0335134f2b077 356 SUPERFAMILY SSF51161 31 328 1.37E-77 T 29-03-2018 IPR011004 Trimeric LpxA-like CDC59_RS09200 7ca4d225aef809701aa0335134f2b077 356 Gene3D G3DSA:2.160.10.10 22 191 2.7E-21 T 29-03-2018 CDC59_RS09200 7ca4d225aef809701aa0335134f2b077 356 Pfam PF04613 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD 24 94 6.1E-20 T 29-03-2018 IPR020573 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region GO:0009245|GO:0016747 CDC59_RS07345 3f43276470ebea33026c7429f6ad639e 505 SMART SM00228 288 370 4.3E-12 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CDC59_RS07345 3f43276470ebea33026c7429f6ad639e 505 SMART SM00228 408 486 3.6E-5 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CDC59_RS07345 3f43276470ebea33026c7429f6ad639e 505 SUPERFAMILY SSF50156 246 370 1.21E-23 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CDC59_RS07345 3f43276470ebea33026c7429f6ad639e 505 PRINTS PR00834 HtrA/DegQ protease family signature 188 212 2.8E-52 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CDC59_RS07345 3f43276470ebea33026c7429f6ad639e 505 PRINTS PR00834 HtrA/DegQ protease family signature 328 340 2.8E-52 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CDC59_RS07345 3f43276470ebea33026c7429f6ad639e 505 PRINTS PR00834 HtrA/DegQ protease family signature 242 259 2.8E-52 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CDC59_RS07345 3f43276470ebea33026c7429f6ad639e 505 PRINTS PR00834 HtrA/DegQ protease family signature 127 139 2.8E-52 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CDC59_RS07345 3f43276470ebea33026c7429f6ad639e 505 PRINTS PR00834 HtrA/DegQ protease family signature 220 237 2.8E-52 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CDC59_RS07345 3f43276470ebea33026c7429f6ad639e 505 PRINTS PR00834 HtrA/DegQ protease family signature 148 168 2.8E-52 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CDC59_RS07345 3f43276470ebea33026c7429f6ad639e 505 Gene3D G3DSA:2.40.10.10 43 188 7.7E-41 T 29-03-2018 CDC59_RS07345 3f43276470ebea33026c7429f6ad639e 505 SUPERFAMILY SSF50156 409 495 6.84E-13 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CDC59_RS07345 3f43276470ebea33026c7429f6ad639e 505 Pfam PF13180 PDZ domain 289 379 3.8E-18 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CDC59_RS07345 3f43276470ebea33026c7429f6ad639e 505 Pfam PF13180 PDZ domain 430 492 4.0E-7 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CDC59_RS07345 3f43276470ebea33026c7429f6ad639e 505 Gene3D G3DSA:2.40.10.10 189 285 2.0E-39 T 29-03-2018 CDC59_RS07345 3f43276470ebea33026c7429f6ad639e 505 Pfam PF13365 Trypsin-like peptidase domain 118 249 2.1E-34 T 29-03-2018 CDC59_RS07345 3f43276470ebea33026c7429f6ad639e 505 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 45 493 1.2E-158 T 29-03-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 CDC59_RS07345 3f43276470ebea33026c7429f6ad639e 505 Gene3D G3DSA:2.30.42.10 286 392 2.0E-25 T 29-03-2018 CDC59_RS07345 3f43276470ebea33026c7429f6ad639e 505 Gene3D G3DSA:2.30.42.10 403 502 1.2E-13 T 29-03-2018 CDC59_RS07345 3f43276470ebea33026c7429f6ad639e 505 SUPERFAMILY SSF50494 43 280 2.91E-68 T 29-03-2018 IPR009003 Peptidase S1, PA clan CDC59_RS19220 5382b8308bb0c05c9b309c5e73a60472 391 Pfam PF16113 Enoyl-CoA hydratase/isomerase 28 370 1.8E-116 T 29-03-2018 IPR032259 Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type GO:0003860 Reactome: R-HSA-70895 CDC59_RS19220 5382b8308bb0c05c9b309c5e73a60472 391 SUPERFAMILY SSF52096 18 212 1.32E-63 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CDC59_RS19220 5382b8308bb0c05c9b309c5e73a60472 391 SUPERFAMILY SSF52096 284 350 1.32E-63 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CDC59_RS19220 5382b8308bb0c05c9b309c5e73a60472 391 Gene3D G3DSA:3.90.226.10 5 364 1.8E-82 T 29-03-2018 CDC59_RS07535 201bd9cd510d628a40ae915e0053b74c 460 Gene3D G3DSA:1.20.1250.20 16 217 3.2E-39 T 29-03-2018 CDC59_RS07535 201bd9cd510d628a40ae915e0053b74c 460 Pfam PF07690 Major Facilitator Superfamily 303 437 1.4E-11 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDC59_RS07535 201bd9cd510d628a40ae915e0053b74c 460 Pfam PF07690 Major Facilitator Superfamily 32 293 1.0E-36 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDC59_RS07535 201bd9cd510d628a40ae915e0053b74c 460 SUPERFAMILY SSF103473 11 445 1.57E-76 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS07535 201bd9cd510d628a40ae915e0053b74c 460 Gene3D G3DSA:1.20.1250.20 245 451 1.4E-20 T 29-03-2018 CDC59_RS07535 201bd9cd510d628a40ae915e0053b74c 460 ProSitePatterns PS00217 Sugar transport proteins signature 2. 123 148 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CDC59_RS03605 cf49d1f8b1ce320de54732edd736fd0c 336 SUPERFAMILY SSF52172 7 148 1.01E-23 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS03605 cf49d1f8b1ce320de54732edd736fd0c 336 Pfam PF00072 Response regulator receiver domain 11 121 3.2E-13 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS03605 cf49d1f8b1ce320de54732edd736fd0c 336 SMART SM00448 9 122 8.6E-13 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS03605 cf49d1f8b1ce320de54732edd736fd0c 336 Gene3D G3DSA:3.40.50.2300 6 316 1.2E-19 T 29-03-2018 CDC59_RS13370 9c409d4b8c7031a9e744d0e0fbbf415c 309 TIGRFAM TIGR01122 ilvE_I: branched-chain amino acid aminotransferase 12 309 1.0E-136 T 29-03-2018 IPR005785 Branched-chain amino acid aminotransferase I GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767 CDC59_RS13370 9c409d4b8c7031a9e744d0e0fbbf415c 309 ProSitePatterns PS00770 Aminotransferases class-IV signature. 195 223 - T 29-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 CDC59_RS13370 9c409d4b8c7031a9e744d0e0fbbf415c 309 Gene3D G3DSA:3.30.470.10 1 143 6.2E-42 T 29-03-2018 CDC59_RS13370 9c409d4b8c7031a9e744d0e0fbbf415c 309 Gene3D G3DSA:3.20.10.10 144 296 1.7E-51 T 29-03-2018 CDC59_RS13370 9c409d4b8c7031a9e744d0e0fbbf415c 309 SUPERFAMILY SSF56752 4 297 4.58E-105 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CDC59_RS13370 9c409d4b8c7031a9e744d0e0fbbf415c 309 Pfam PF01063 Amino-transferase class IV 37 267 3.5E-59 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CDC59_RS08175 37e6663dbbd450a77fc21f67a88d546e 388 TIGRFAM TIGR03300 assembly_YfgL: outer membrane assembly lipoprotein YfgL 17 385 2.5E-135 T 29-03-2018 IPR017687 Outer membrane protein assembly factor BamB CDC59_RS08175 37e6663dbbd450a77fc21f67a88d546e 388 Gene3D G3DSA:2.140.10.10 283 388 3.9E-14 T 29-03-2018 CDC59_RS08175 37e6663dbbd450a77fc21f67a88d546e 388 Pfam PF13360 PQQ-like domain 84 314 1.8E-56 T 29-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat CDC59_RS08175 37e6663dbbd450a77fc21f67a88d546e 388 Gene3D G3DSA:2.140.10.10 34 183 3.2E-22 T 29-03-2018 CDC59_RS08175 37e6663dbbd450a77fc21f67a88d546e 388 Gene3D G3DSA:2.140.10.10 184 282 2.1E-11 T 29-03-2018 CDC59_RS08175 37e6663dbbd450a77fc21f67a88d546e 388 SUPERFAMILY SSF50998 37 379 4.08E-72 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CDC59_RS08175 37e6663dbbd450a77fc21f67a88d546e 388 SMART SM00564 71 102 0.073 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CDC59_RS08175 37e6663dbbd450a77fc21f67a88d546e 388 SMART SM00564 149 181 0.2 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CDC59_RS08175 37e6663dbbd450a77fc21f67a88d546e 388 SMART SM00564 324 356 5.1 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CDC59_RS08175 37e6663dbbd450a77fc21f67a88d546e 388 SMART SM00564 283 315 13.0 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CDC59_RS08175 37e6663dbbd450a77fc21f67a88d546e 388 SMART SM00564 194 226 62.0 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CDC59_RS08175 37e6663dbbd450a77fc21f67a88d546e 388 Hamap MF_00923 Outer membrane protein assembly factor BamB [bamB]. 12 387 38.087 T 29-03-2018 IPR017687 Outer membrane protein assembly factor BamB CDC59_RS19395 9d579158db0f25feb7406098cc635381 273 SUPERFAMILY SSF46689 169 218 4.48E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS19395 9d579158db0f25feb7406098cc635381 273 SUPERFAMILY SSF46689 222 265 1.43E-5 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS19395 9d579158db0f25feb7406098cc635381 273 Pfam PF12833 Helix-turn-helix domain 190 264 4.6E-17 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CDC59_RS19395 9d579158db0f25feb7406098cc635381 273 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 221 262 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CDC59_RS19395 9d579158db0f25feb7406098cc635381 273 Pfam PF02311 AraC-like ligand binding domain 21 152 3.3E-22 T 29-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CDC59_RS19395 9d579158db0f25feb7406098cc635381 273 SMART SM00342 184 266 2.4E-21 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CDC59_RS19395 9d579158db0f25feb7406098cc635381 273 Gene3D G3DSA:1.10.10.60 167 223 2.9E-14 T 29-03-2018 CDC59_RS19395 9d579158db0f25feb7406098cc635381 273 Gene3D G3DSA:1.10.10.60 224 272 3.6E-8 T 29-03-2018 CDC59_RS19395 9d579158db0f25feb7406098cc635381 273 SUPERFAMILY SSF51215 22 152 4.84E-16 T 29-03-2018 CDC59_RS19395 9d579158db0f25feb7406098cc635381 273 Gene3D G3DSA:2.60.120.10 6 94 2.2E-5 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CDC59_RS18435 d3fe623b5ac344096e95d6d88579ccf3 449 Pfam PF13535 ATP-grasp domain 145 313 3.6E-8 T 29-03-2018 CDC59_RS18435 d3fe623b5ac344096e95d6d88579ccf3 449 SUPERFAMILY SSF56059 111 337 1.68E-26 T 29-03-2018 CDC59_RS18435 d3fe623b5ac344096e95d6d88579ccf3 449 Gene3D G3DSA:3.40.50.20 21 114 8.5E-4 T 29-03-2018 CDC59_RS18435 d3fe623b5ac344096e95d6d88579ccf3 449 Gene3D G3DSA:3.30.470.20 115 439 2.1E-31 T 29-03-2018 CDC59_RS23040 83d422d96a255d59f4d7e2080c06ee92 209 SUPERFAMILY SSF110849 49 182 4.88E-16 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CDC59_RS23040 83d422d96a255d59f4d7e2080c06ee92 209 Gene3D G3DSA:3.90.1530.10 41 139 1.4E-9 T 29-03-2018 CDC59_RS23040 83d422d96a255d59f4d7e2080c06ee92 209 SMART SM00470 51 148 0.0041 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CDC59_RS23040 83d422d96a255d59f4d7e2080c06ee92 209 Gene3D G3DSA:1.10.10.60 140 191 0.0011 T 29-03-2018 CDC59_RS23040 83d422d96a255d59f4d7e2080c06ee92 209 Pfam PF02195 ParB-like nuclease domain 52 114 3.5E-8 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CDC59_RS18720 b9f6bc82dd7a53b90474cd13a2e16d4d 698 Gene3D G3DSA:3.90.550.10 35 350 3.0E-13 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDC59_RS18720 b9f6bc82dd7a53b90474cd13a2e16d4d 698 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 532 620 3.9E-13 T 29-03-2018 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 CDC59_RS18720 b9f6bc82dd7a53b90474cd13a2e16d4d 698 SUPERFAMILY SSF53448 69 296 3.6E-11 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDC59_RS18720 b9f6bc82dd7a53b90474cd13a2e16d4d 698 Pfam PF13632 Glycosyl transferase family group 2 164 392 1.0E-38 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CDC59_RS18720 b9f6bc82dd7a53b90474cd13a2e16d4d 698 SUPERFAMILY SSF160246 495 626 1.57E-27 T 29-03-2018 CDC59_RS07400 4dbb9fe3f70e7f299bf644c2d5f7b26a 191 TIGRFAM TIGR00038 efp: translation elongation factor P 6 190 9.8E-62 T 29-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 CDC59_RS07400 4dbb9fe3f70e7f299bf644c2d5f7b26a 191 Gene3D G3DSA:2.40.50.140 66 129 2.6E-23 T 29-03-2018 CDC59_RS07400 4dbb9fe3f70e7f299bf644c2d5f7b26a 191 Pfam PF01132 Elongation factor P (EF-P) OB domain 70 123 8.4E-20 T 29-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 CDC59_RS07400 4dbb9fe3f70e7f299bf644c2d5f7b26a 191 Gene3D G3DSA:2.30.30.30 4 63 4.7E-17 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 CDC59_RS07400 4dbb9fe3f70e7f299bf644c2d5f7b26a 191 PIRSF PIRSF005901 2 191 5.7E-53 T 29-03-2018 IPR020599 Translation elongation factor P/YeiP CDC59_RS07400 4dbb9fe3f70e7f299bf644c2d5f7b26a 191 SUPERFAMILY SSF50249 67 129 2.06E-18 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDC59_RS07400 4dbb9fe3f70e7f299bf644c2d5f7b26a 191 SUPERFAMILY SSF50104 6 65 5.3E-15 T 29-03-2018 IPR008991 Translation protein SH3-like domain CDC59_RS07400 4dbb9fe3f70e7f299bf644c2d5f7b26a 191 Pfam PF09285 Elongation factor P, C-terminal 131 189 4.0E-21 T 29-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 CDC59_RS07400 4dbb9fe3f70e7f299bf644c2d5f7b26a 191 SMART SM01185 69 123 3.2E-24 T 29-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 CDC59_RS07400 4dbb9fe3f70e7f299bf644c2d5f7b26a 191 SMART SM00841 131 189 4.8E-24 T 29-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 CDC59_RS07400 4dbb9fe3f70e7f299bf644c2d5f7b26a 191 SUPERFAMILY SSF50249 130 190 1.37E-11 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDC59_RS07400 4dbb9fe3f70e7f299bf644c2d5f7b26a 191 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 6 62 3.7E-16 T 29-03-2018 IPR013185 Translation elongation factor, KOW-like CDC59_RS07400 4dbb9fe3f70e7f299bf644c2d5f7b26a 191 Hamap MF_00141 Elongation factor P [efp]. 3 190 43.736 T 29-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 CDC59_RS07400 4dbb9fe3f70e7f299bf644c2d5f7b26a 191 Gene3D G3DSA:2.40.50.140 131 189 1.5E-21 T 29-03-2018 CDC59_RS03200 52a56c407d86692f0d0f2c8fcf00d5a1 72 SUPERFAMILY SSF57716 3 58 1.05E-21 T 29-03-2018 CDC59_RS03200 52a56c407d86692f0d0f2c8fcf00d5a1 72 Pfam PF03884 DNA gyrase inhibitor YacG 7 53 4.7E-25 T 29-03-2018 IPR005584 DNA gyrase inhibitor YacG GO:0008270 CDC59_RS03200 52a56c407d86692f0d0f2c8fcf00d5a1 72 Hamap MF_00649 DNA gyrase inhibitor YacG [yacG]. 3 60 20.123 T 29-03-2018 IPR005584 DNA gyrase inhibitor YacG GO:0008270 CDC59_RS03200 52a56c407d86692f0d0f2c8fcf00d5a1 72 Gene3D G3DSA:3.30.50.10 2 59 1.4E-25 T 29-03-2018 IPR013088 Zinc finger, NHR/GATA-type GO:0006355|GO:0008270 CDC59_RS01965 16aa8f9e809bcb4ebcbe09f0b85ea050 243 SUPERFAMILY SSF52172 7 130 1.34E-37 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS01965 16aa8f9e809bcb4ebcbe09f0b85ea050 243 SMART SM00448 8 118 8.2E-38 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS01965 16aa8f9e809bcb4ebcbe09f0b85ea050 243 Gene3D G3DSA:3.40.50.2300 1 131 9.0E-34 T 29-03-2018 CDC59_RS01965 16aa8f9e809bcb4ebcbe09f0b85ea050 243 SUPERFAMILY SSF46894 138 237 2.38E-25 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CDC59_RS01965 16aa8f9e809bcb4ebcbe09f0b85ea050 243 Pfam PF00072 Response regulator receiver domain 10 118 3.0E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS01965 16aa8f9e809bcb4ebcbe09f0b85ea050 243 Gene3D G3DSA:1.10.10.10 132 243 2.1E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS01965 16aa8f9e809bcb4ebcbe09f0b85ea050 243 SMART SM00862 160 236 1.1E-20 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDC59_RS01965 16aa8f9e809bcb4ebcbe09f0b85ea050 243 Pfam PF00486 Transcriptional regulatory protein, C terminal 160 236 6.2E-21 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDC59_RS13055 86197add95b6b4a6ce8b4d727168eccd 96 SMART SM00883 2 94 2.4E-56 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CDC59_RS13055 86197add95b6b4a6ce8b4d727168eccd 96 Gene3D G3DSA:2.30.33.40 1 95 3.7E-39 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CDC59_RS13055 86197add95b6b4a6ce8b4d727168eccd 96 ProSitePatterns PS00681 Chaperonins cpn10 signature. 3 27 - T 29-03-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 CDC59_RS13055 86197add95b6b4a6ce8b4d727168eccd 96 PRINTS PR00297 10kDa chaperonin signature 60 72 2.1E-33 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CDC59_RS13055 86197add95b6b4a6ce8b4d727168eccd 96 PRINTS PR00297 10kDa chaperonin signature 3 18 2.1E-33 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CDC59_RS13055 86197add95b6b4a6ce8b4d727168eccd 96 PRINTS PR00297 10kDa chaperonin signature 25 46 2.1E-33 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CDC59_RS13055 86197add95b6b4a6ce8b4d727168eccd 96 PRINTS PR00297 10kDa chaperonin signature 81 94 2.1E-33 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CDC59_RS13055 86197add95b6b4a6ce8b4d727168eccd 96 Pfam PF00166 Chaperonin 10 Kd subunit 2 94 2.4E-35 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CDC59_RS13055 86197add95b6b4a6ce8b4d727168eccd 96 SUPERFAMILY SSF50129 1 94 4.43E-34 T 29-03-2018 IPR011032 GroES-like CDC59_RS13055 86197add95b6b4a6ce8b4d727168eccd 96 Hamap MF_00580 10 kDa chaperonin [groS]. 2 95 26.637 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CDC59_RS10000 8caab15fb3ca4d7ef1c8e79b86680f21 545 Gene3D G3DSA:3.30.300.30 435 538 1.8E-22 T 29-03-2018 CDC59_RS10000 8caab15fb3ca4d7ef1c8e79b86680f21 545 SUPERFAMILY SSF56801 13 538 1.05E-128 T 29-03-2018 CDC59_RS10000 8caab15fb3ca4d7ef1c8e79b86680f21 545 Gene3D G3DSA:2.30.38.10 363 434 4.3E-13 T 29-03-2018 CDC59_RS10000 8caab15fb3ca4d7ef1c8e79b86680f21 545 ProSitePatterns PS00455 Putative AMP-binding domain signature. 186 197 - T 29-03-2018 IPR020845 AMP-binding, conserved site CDC59_RS10000 8caab15fb3ca4d7ef1c8e79b86680f21 545 Pfam PF00501 AMP-binding enzyme 20 441 4.9E-83 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CDC59_RS10000 8caab15fb3ca4d7ef1c8e79b86680f21 545 Gene3D G3DSA:3.40.50.980 193 349 2.6E-36 T 29-03-2018 CDC59_RS10000 8caab15fb3ca4d7ef1c8e79b86680f21 545 Pfam PF13193 AMP-binding enzyme C-terminal domain 451 525 5.4E-13 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CDC59_RS10000 8caab15fb3ca4d7ef1c8e79b86680f21 545 Gene3D G3DSA:3.40.50.980 12 192 1.1E-31 T 29-03-2018 CDC59_RS03870 e9b4d0a57e1c6948f42d7ceeb6c0765e 347 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 193 207 - T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CDC59_RS03870 e9b4d0a57e1c6948f42d7ceeb6c0765e 347 Gene3D G3DSA:3.30.450.90 1 100 4.7E-27 T 29-03-2018 CDC59_RS03870 e9b4d0a57e1c6948f42d7ceeb6c0765e 347 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 3 343 1.7E-151 T 29-03-2018 IPR006321 Pilus retraction protein PilT GO:0005524|GO:0006810 CDC59_RS03870 e9b4d0a57e1c6948f42d7ceeb6c0765e 347 Gene3D G3DSA:3.40.50.300 273 347 1.6E-13 T 29-03-2018 CDC59_RS03870 e9b4d0a57e1c6948f42d7ceeb6c0765e 347 Gene3D G3DSA:3.40.50.300 114 272 2.4E-28 T 29-03-2018 CDC59_RS03870 e9b4d0a57e1c6948f42d7ceeb6c0765e 347 SMART SM00382 122 256 0.0043 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS03870 e9b4d0a57e1c6948f42d7ceeb6c0765e 347 SUPERFAMILY SSF52540 5 336 2.48E-76 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS03870 e9b4d0a57e1c6948f42d7ceeb6c0765e 347 Pfam PF00437 Type II/IV secretion system protein 10 268 1.5E-44 T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CDC59_RS15755 35478c8b5e0ffbf6686cad32d7651581 443 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 42 442 2.1E-94 T 29-03-2018 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CDC59_RS15755 35478c8b5e0ffbf6686cad32d7651581 443 SUPERFAMILY SSF48013 22 153 8.83E-21 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CDC59_RS15755 35478c8b5e0ffbf6686cad32d7651581 443 Gene3D G3DSA:1.10.940.10 9 149 3.1E-20 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CDC59_RS15755 35478c8b5e0ffbf6686cad32d7651581 443 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 318 329 - T 29-03-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CDC59_RS15755 35478c8b5e0ffbf6686cad32d7651581 443 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 253 263 4.4E-25 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CDC59_RS15755 35478c8b5e0ffbf6686cad32d7651581 443 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 369 385 4.4E-25 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CDC59_RS15755 35478c8b5e0ffbf6686cad32d7651581 443 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 224 238 4.4E-25 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CDC59_RS15755 35478c8b5e0ffbf6686cad32d7651581 443 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 319 331 4.4E-25 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CDC59_RS15755 35478c8b5e0ffbf6686cad32d7651581 443 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 424 441 4.4E-25 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CDC59_RS15755 35478c8b5e0ffbf6686cad32d7651581 443 Gene3D G3DSA:3.30.70.1170 177 232 4.0E-15 T 29-03-2018 CDC59_RS15755 35478c8b5e0ffbf6686cad32d7651581 443 Pfam PF01189 16S rRNA methyltransferase RsmB/F 242 439 1.0E-51 T 29-03-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CDC59_RS15755 35478c8b5e0ffbf6686cad32d7651581 443 SUPERFAMILY SSF53335 143 442 7.37E-68 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS15755 35478c8b5e0ffbf6686cad32d7651581 443 Gene3D G3DSA:1.10.287.730 150 176 4.6E-11 T 29-03-2018 CDC59_RS15755 35478c8b5e0ffbf6686cad32d7651581 443 Gene3D G3DSA:3.40.50.150 233 443 1.7E-52 T 29-03-2018 CDC59_RS15755 35478c8b5e0ffbf6686cad32d7651581 443 Pfam PF01029 NusB family 42 130 1.1E-7 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CDC59_RS15760 0e50ab1e2ed3f312684cc2ccc227c294 286 Pfam PF01435 Peptidase family M48 66 278 8.6E-37 T 29-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CDC59_RS15760 0e50ab1e2ed3f312684cc2ccc227c294 286 Gene3D G3DSA:3.30.2010.10 56 149 6.5E-23 T 29-03-2018 CDC59_RS15760 0e50ab1e2ed3f312684cc2ccc227c294 286 Hamap MF_00188 Protease HtpX [htpX]. 4 278 29.385 T 29-03-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 CDC59_RS02995 2766bffb642c0214e5b3690383ebd4cf 396 PIRSF PIRSF005962 2 396 4.4E-131 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CDC59_RS02995 2766bffb642c0214e5b3690383ebd4cf 396 Pfam PF01546 Peptidase family M20/M25/M40 72 390 3.2E-37 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CDC59_RS02995 2766bffb642c0214e5b3690383ebd4cf 396 Pfam PF07687 Peptidase dimerisation domain 184 282 2.3E-9 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CDC59_RS02995 2766bffb642c0214e5b3690383ebd4cf 396 SUPERFAMILY SSF55031 182 295 1.57E-31 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CDC59_RS02995 2766bffb642c0214e5b3690383ebd4cf 396 Gene3D G3DSA:3.40.630.10 2 213 2.1E-52 T 29-03-2018 CDC59_RS02995 2766bffb642c0214e5b3690383ebd4cf 396 Gene3D G3DSA:3.40.630.10 214 396 1.2E-25 T 29-03-2018 CDC59_RS02995 2766bffb642c0214e5b3690383ebd4cf 396 SUPERFAMILY SSF53187 4 196 2.1E-91 T 29-03-2018 CDC59_RS02995 2766bffb642c0214e5b3690383ebd4cf 396 SUPERFAMILY SSF53187 297 393 2.1E-91 T 29-03-2018 CDC59_RS02995 2766bffb642c0214e5b3690383ebd4cf 396 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 16 380 4.6E-111 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CDC59_RS19860 c1fe625cf96aee230657ef3f0a03c0b1 700 Pfam PF03764 Elongation factor G, domain IV 484 603 7.7E-47 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CDC59_RS19860 c1fe625cf96aee230657ef3f0a03c0b1 700 PRINTS PR00315 GTP-binding elongation factor signature 137 146 1.9E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDC59_RS19860 c1fe625cf96aee230657ef3f0a03c0b1 700 PRINTS PR00315 GTP-binding elongation factor signature 58 66 1.9E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDC59_RS19860 c1fe625cf96aee230657ef3f0a03c0b1 700 PRINTS PR00315 GTP-binding elongation factor signature 101 112 1.9E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDC59_RS19860 c1fe625cf96aee230657ef3f0a03c0b1 700 PRINTS PR00315 GTP-binding elongation factor signature 85 95 1.9E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDC59_RS19860 c1fe625cf96aee230657ef3f0a03c0b1 700 PRINTS PR00315 GTP-binding elongation factor signature 12 25 1.9E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDC59_RS19860 c1fe625cf96aee230657ef3f0a03c0b1 700 Hamap MF_00054_B Elongation factor G [fusA]. 6 698 110.746 T 29-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CDC59_RS19860 c1fe625cf96aee230657ef3f0a03c0b1 700 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 699 0.0 T 29-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CDC59_RS19860 c1fe625cf96aee230657ef3f0a03c0b1 700 Pfam PF14492 Elongation Factor G, domain II 409 483 2.2E-35 T 29-03-2018 CDC59_RS19860 c1fe625cf96aee230657ef3f0a03c0b1 700 SUPERFAMILY SSF54211 484 604 4.3E-41 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CDC59_RS19860 c1fe625cf96aee230657ef3f0a03c0b1 700 SUPERFAMILY SSF54980 409 486 5.76E-26 T 29-03-2018 IPR035647 EF-G domain III/V-like CDC59_RS19860 c1fe625cf96aee230657ef3f0a03c0b1 700 Gene3D G3DSA:3.30.230.10 499 613 2.9E-41 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CDC59_RS19860 c1fe625cf96aee230657ef3f0a03c0b1 700 SUPERFAMILY SSF52540 6 288 2.1E-107 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS19860 c1fe625cf96aee230657ef3f0a03c0b1 700 SMART SM00889 485 603 1.0E-71 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CDC59_RS19860 c1fe625cf96aee230657ef3f0a03c0b1 700 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site CDC59_RS19860 c1fe625cf96aee230657ef3f0a03c0b1 700 Gene3D G3DSA:3.30.70.870 407 498 7.1E-38 T 29-03-2018 CDC59_RS19860 c1fe625cf96aee230657ef3f0a03c0b1 700 SUPERFAMILY SSF50447 310 407 1.39E-36 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CDC59_RS19860 c1fe625cf96aee230657ef3f0a03c0b1 700 SUPERFAMILY SSF50447 255 281 1.39E-36 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CDC59_RS19860 c1fe625cf96aee230657ef3f0a03c0b1 700 SMART SM00838 605 694 9.5E-55 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like CDC59_RS19860 c1fe625cf96aee230657ef3f0a03c0b1 700 Pfam PF00679 Elongation factor G C-terminus 605 692 9.4E-31 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like CDC59_RS19860 c1fe625cf96aee230657ef3f0a03c0b1 700 Pfam PF03144 Elongation factor Tu domain 2 329 396 1.1E-17 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CDC59_RS19860 c1fe625cf96aee230657ef3f0a03c0b1 700 Pfam PF00009 Elongation factor Tu GTP binding domain 9 288 1.1E-66 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDC59_RS19860 c1fe625cf96aee230657ef3f0a03c0b1 700 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 187 1.7E-32 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CDC59_RS19860 c1fe625cf96aee230657ef3f0a03c0b1 700 Gene3D G3DSA:2.40.30.10 294 406 1.8E-30 T 29-03-2018 CDC59_RS19860 c1fe625cf96aee230657ef3f0a03c0b1 700 SUPERFAMILY SSF54980 608 696 3.74E-30 T 29-03-2018 IPR035647 EF-G domain III/V-like CDC59_RS19860 c1fe625cf96aee230657ef3f0a03c0b1 700 Gene3D G3DSA:3.30.70.240 614 693 2.3E-31 T 29-03-2018 CDC59_RS19860 c1fe625cf96aee230657ef3f0a03c0b1 700 Gene3D G3DSA:3.40.50.300 1 293 3.9E-59 T 29-03-2018 CDC59_RS18835 0b4ff7f7e66038b9722e22f29f7ef4fc 390 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 59 381 3.3E-46 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 CDC59_RS18835 0b4ff7f7e66038b9722e22f29f7ef4fc 390 SUPERFAMILY SSF111369 83 310 9.68E-21 T 29-03-2018 CDC59_RS18835 0b4ff7f7e66038b9722e22f29f7ef4fc 390 Gene3D G3DSA:3.90.1170.30 15 127 1.4E-5 T 29-03-2018 CDC59_RS18835 0b4ff7f7e66038b9722e22f29f7ef4fc 390 Gene3D G3DSA:1.20.1600.10 128 290 2.0E-11 T 29-03-2018 CDC59_RS18835 0b4ff7f7e66038b9722e22f29f7ef4fc 390 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 68 306 3.2E-60 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CDC59_RS02395 4bb35480f13d38c4aeb5a4dd54fc349e 219 Pfam PF00034 Cytochrome c 136 217 1.0E-7 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS02395 4bb35480f13d38c4aeb5a4dd54fc349e 219 Pfam PF00034 Cytochrome c 34 118 7.5E-9 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS02395 4bb35480f13d38c4aeb5a4dd54fc349e 219 SUPERFAMILY SSF46626 131 217 5.08E-21 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS02395 4bb35480f13d38c4aeb5a4dd54fc349e 219 SUPERFAMILY SSF46626 31 118 1.4E-21 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS02395 4bb35480f13d38c4aeb5a4dd54fc349e 219 PRINTS PR00605 Class IC cytochrome C signature 51 62 2.3E-5 T 29-03-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 CDC59_RS02395 4bb35480f13d38c4aeb5a4dd54fc349e 219 PRINTS PR00605 Class IC cytochrome C signature 94 116 2.3E-5 T 29-03-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 CDC59_RS02395 4bb35480f13d38c4aeb5a4dd54fc349e 219 PIRSF PIRSF000005 1 219 1.7E-67 T 29-03-2018 IPR024167 Cytochrome c4-like GO:0005506|GO:0009055|GO:0020037|GO:0042597 CDC59_RS02395 4bb35480f13d38c4aeb5a4dd54fc349e 219 Gene3D G3DSA:1.10.760.10 14 119 3.4E-26 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS02395 4bb35480f13d38c4aeb5a4dd54fc349e 219 Gene3D G3DSA:1.10.760.10 122 217 8.2E-23 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS00805 f5881fb1a501d86be0cff69c74ad0a76 261 Gene3D G3DSA:3.40.50.300 1 261 3.4E-59 T 29-03-2018 CDC59_RS00805 f5881fb1a501d86be0cff69c74ad0a76 261 SUPERFAMILY SSF52540 1 255 1.18E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS00805 f5881fb1a501d86be0cff69c74ad0a76 261 Pfam PF13614 AAA domain 4 178 2.6E-62 T 29-03-2018 IPR025669 AAA domain CDC59_RS00805 f5881fb1a501d86be0cff69c74ad0a76 261 PIRSF PIRSF009320 2 69 9.0E-14 T 29-03-2018 CDC59_RS00805 f5881fb1a501d86be0cff69c74ad0a76 261 PIRSF PIRSF009320 87 258 4.0E-9 T 29-03-2018 CDC59_RS23350 6ffef03eeeb454287c929e79aff86ead 257 PIRSF PIRSF028589 1 257 4.8E-113 T 29-03-2018 IPR016893 Protein of unknown function UCP028589 CDC59_RS16065 bc0bce97490ee2f8ee1d7ad85e59f80b 159 Gene3D G3DSA:3.90.280.10 1 157 1.3E-53 T 29-03-2018 IPR008914 Phosphatidylethanolamine-binding protein CDC59_RS16065 bc0bce97490ee2f8ee1d7ad85e59f80b 159 SUPERFAMILY SSF49777 1 148 4.58E-48 T 29-03-2018 IPR008914 Phosphatidylethanolamine-binding protein CDC59_RS16065 bc0bce97490ee2f8ee1d7ad85e59f80b 159 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 20 153 8.6E-38 T 29-03-2018 IPR005247 YbhB/YbcL CDC59_RS16065 bc0bce97490ee2f8ee1d7ad85e59f80b 159 Pfam PF01161 Phosphatidylethanolamine-binding protein 20 154 1.8E-41 T 29-03-2018 IPR008914 Phosphatidylethanolamine-binding protein CDC59_RS18895 ddc45d425e9b36f5e9708a455a8c90db 144 SUPERFAMILY SSF54523 42 143 2.77E-32 T 29-03-2018 CDC59_RS18895 ddc45d425e9b36f5e9708a455a8c90db 144 TIGRFAM TIGR01710 typeII_sec_gspG: type II secretion system protein G 14 144 5.0E-49 T 29-03-2018 IPR010054 General secretion pathway protein G GO:0008565|GO:0015627|GO:0015628 CDC59_RS18895 ddc45d425e9b36f5e9708a455a8c90db 144 PRINTS PR00813 Bacterial general secretion pathway protein G signature 51 69 2.1E-16 T 29-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 CDC59_RS18895 ddc45d425e9b36f5e9708a455a8c90db 144 PRINTS PR00813 Bacterial general secretion pathway protein G signature 15 40 2.1E-16 T 29-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 CDC59_RS18895 ddc45d425e9b36f5e9708a455a8c90db 144 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 14 35 7.1E-9 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS18895 ddc45d425e9b36f5e9708a455a8c90db 144 Pfam PF07963 Prokaryotic N-terminal methylation motif 13 34 4.1E-8 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS18895 ddc45d425e9b36f5e9708a455a8c90db 144 Pfam PF08334 Type II secretion system (T2SS), protein G 39 144 1.3E-40 T 29-03-2018 IPR013545 Type II secretion system protein G CDC59_RS18895 ddc45d425e9b36f5e9708a455a8c90db 144 Gene3D G3DSA:3.30.700.10 29 142 1.2E-23 T 29-03-2018 CDC59_RS19080 96e8f7ccaa0bb17aae2102e82c702b41 525 TIGRFAM TIGR00715 precor6x_red: precorrin-6x reductase 260 500 4.9E-63 T 29-03-2018 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 CDC59_RS19080 96e8f7ccaa0bb17aae2102e82c702b41 525 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 210 5.9E-36 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CDC59_RS19080 96e8f7ccaa0bb17aae2102e82c702b41 525 Gene3D G3DSA:3.40.1010.10 2 122 3.0E-28 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CDC59_RS19080 96e8f7ccaa0bb17aae2102e82c702b41 525 Gene3D G3DSA:3.30.950.10 123 240 5.8E-44 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CDC59_RS19080 96e8f7ccaa0bb17aae2102e82c702b41 525 Gene3D G3DSA:3.40.50.2300 325 512 1.2E-12 T 29-03-2018 CDC59_RS19080 96e8f7ccaa0bb17aae2102e82c702b41 525 SUPERFAMILY SSF53790 1 244 7.85E-49 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CDC59_RS19080 96e8f7ccaa0bb17aae2102e82c702b41 525 Pfam PF02571 Precorrin-6x reductase CbiJ/CobK 261 508 3.9E-74 T 29-03-2018 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 CDC59_RS19080 96e8f7ccaa0bb17aae2102e82c702b41 525 TIGRFAM TIGR01466 cobJ_cbiH: precorrin-3B C17-methyltransferase 5 241 8.0E-96 T 29-03-2018 IPR006363 Precorrin-3B C17-methyltransferase domain GO:0008168|GO:0009236 CDC59_RS12230 6a93eca14557715013479e8330b3a1a1 998 SMART SM00926 82 136 1.1E-12 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS12230 6a93eca14557715013479e8330b3a1a1 998 Pfam PF00384 Molybdopterin oxidoreductase 139 594 6.5E-57 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS12230 6a93eca14557715013479e8330b3a1a1 998 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 84 133 9.9E-11 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS12230 6a93eca14557715013479e8330b3a1a1 998 Pfam PF01568 Molydopterin dinucleotide binding domain 864 990 1.2E-18 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CDC59_RS12230 6a93eca14557715013479e8330b3a1a1 998 SUPERFAMILY SSF53706 81 642 1.05E-200 T 29-03-2018 CDC59_RS12230 6a93eca14557715013479e8330b3a1a1 998 Gene3D G3DSA:2.20.25.90 75 141 1.6E-13 T 29-03-2018 CDC59_RS12230 6a93eca14557715013479e8330b3a1a1 998 PIRSF PIRSF036643 57 612 1.9E-115 T 29-03-2018 CDC59_RS12230 6a93eca14557715013479e8330b3a1a1 998 PIRSF PIRSF036643 826 998 4.1E-15 T 29-03-2018 CDC59_RS12230 6a93eca14557715013479e8330b3a1a1 998 Gene3D G3DSA:2.40.40.20 807 996 5.0E-36 T 29-03-2018 CDC59_RS12230 6a93eca14557715013479e8330b3a1a1 998 Gene3D G3DSA:3.40.50.740 333 697 7.9E-62 T 29-03-2018 CDC59_RS12230 6a93eca14557715013479e8330b3a1a1 998 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 87 104 - T 29-03-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 CDC59_RS12230 6a93eca14557715013479e8330b3a1a1 998 Gene3D G3DSA:3.40.50.740 142 332 3.4E-45 T 29-03-2018 CDC59_RS12230 6a93eca14557715013479e8330b3a1a1 998 SUPERFAMILY SSF50692 829 996 1.42E-38 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain CDC59_RS15155 f77b9ca6e09f7ff5bddce01b7e0b246f 398 Pfam PF06772 Bacterial low temperature requirement A protein (LtrA) 18 377 7.5E-113 T 29-03-2018 IPR010640 Low temperature requirement A CDC59_RS19970 24781fe4800fcc72352576c2c4d2d9b5 292 Pfam PF00892 EamA-like transporter family 6 135 2.3E-14 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CDC59_RS19970 24781fe4800fcc72352576c2c4d2d9b5 292 Pfam PF00892 EamA-like transporter family 146 279 5.0E-11 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CDC59_RS19970 24781fe4800fcc72352576c2c4d2d9b5 292 SUPERFAMILY SSF103481 39 137 1.09E-8 T 29-03-2018 CDC59_RS19970 24781fe4800fcc72352576c2c4d2d9b5 292 SUPERFAMILY SSF103481 180 281 3.01E-10 T 29-03-2018 CDC59_RS17830 04a7469bc2daedf76de5f303f5e5aae2 187 TIGRFAM TIGR03137 AhpC: peroxiredoxin 1 187 1.4E-96 T 29-03-2018 IPR017559 Alkyl hydroperoxide reductase subunit C GO:0006979|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CDC59_RS17830 04a7469bc2daedf76de5f303f5e5aae2 187 PIRSF PIRSF000239 1 187 1.4E-46 T 29-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CDC59_RS17830 04a7469bc2daedf76de5f303f5e5aae2 187 Pfam PF00578 AhpC/TSA family 4 132 1.6E-29 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CDC59_RS17830 04a7469bc2daedf76de5f303f5e5aae2 187 SUPERFAMILY SSF52833 2 186 1.2E-50 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS17830 04a7469bc2daedf76de5f303f5e5aae2 187 Gene3D G3DSA:3.30.1020.10 153 183 7.6E-10 T 29-03-2018 CDC59_RS17830 04a7469bc2daedf76de5f303f5e5aae2 187 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 156 182 3.0E-5 T 29-03-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CDC59_RS17830 04a7469bc2daedf76de5f303f5e5aae2 187 Gene3D G3DSA:3.40.30.10 4 152 4.9E-31 T 29-03-2018 CDC59_RS01475 df139a540205190facd5903b4dc87e0b 384 Gene3D G3DSA:3.40.640.10 57 264 3.2E-46 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDC59_RS01475 df139a540205190facd5903b4dc87e0b 384 SUPERFAMILY SSF53383 37 371 4.12E-72 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS01475 df139a540205190facd5903b4dc87e0b 384 Gene3D G3DSA:3.90.1150.10 265 374 2.4E-11 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS01475 df139a540205190facd5903b4dc87e0b 384 Pfam PF00155 Aminotransferase class I and II 53 362 1.5E-38 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CDC59_RS03980 58a73887cd1af46a6f6cd4d89622fee9 359 SUPERFAMILY SSF51569 7 351 9.73E-137 T 29-03-2018 CDC59_RS03980 58a73887cd1af46a6f6cd4d89622fee9 359 Gene3D G3DSA:3.20.20.70 8 357 4.4E-132 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS03980 58a73887cd1af46a6f6cd4d89622fee9 359 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 6 352 1.6E-164 T 29-03-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CDC59_RS03980 58a73887cd1af46a6f6cd4d89622fee9 359 PIRSF PIRSF001361 1 354 7.0E-160 T 29-03-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CDC59_RS03980 58a73887cd1af46a6f6cd4d89622fee9 359 Pfam PF00793 DAHP synthetase I family 43 340 5.4E-103 T 29-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 CDC59_RS17325 c6df8557ac543ff2dc114c8edcebd682 808 SUPERFAMILY SSF56935 108 808 3.66E-88 T 29-03-2018 CDC59_RS17325 c6df8557ac543ff2dc114c8edcebd682 808 Gene3D G3DSA:2.40.170.20 235 807 6.9E-53 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CDC59_RS17325 c6df8557ac543ff2dc114c8edcebd682 808 Pfam PF07715 TonB-dependent Receptor Plug Domain 133 232 1.4E-19 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CDC59_RS17325 c6df8557ac543ff2dc114c8edcebd682 808 Gene3D G3DSA:2.170.130.10 108 234 2.7E-23 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CDC59_RS17325 c6df8557ac543ff2dc114c8edcebd682 808 Pfam PF00593 TonB dependent receptor 349 805 2.6E-41 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CDC59_RS17325 c6df8557ac543ff2dc114c8edcebd682 808 SMART SM00965 43 94 1.7E-11 T 29-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 CDC59_RS17325 c6df8557ac543ff2dc114c8edcebd682 808 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 137 787 1.2E-99 T 29-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 CDC59_RS03135 b504d825ae3ca830c8417f3268c50f47 483 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 7 460 1.3E-163 T 29-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDC59_RS03135 b504d825ae3ca830c8417f3268c50f47 483 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 5 468 43.252 T 29-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDC59_RS03135 b504d825ae3ca830c8417f3268c50f47 483 SUPERFAMILY SSF51984 6 92 1.96E-28 T 29-03-2018 CDC59_RS03135 b504d825ae3ca830c8417f3268c50f47 483 SUPERFAMILY SSF53623 91 312 4.45E-71 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CDC59_RS03135 b504d825ae3ca830c8417f3268c50f47 483 Gene3D G3DSA:3.40.50.720 2 93 3.4E-17 T 29-03-2018 CDC59_RS03135 b504d825ae3ca830c8417f3268c50f47 483 SUPERFAMILY SSF53244 313 459 2.01E-43 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CDC59_RS03135 b504d825ae3ca830c8417f3268c50f47 483 Pfam PF08245 Mur ligase middle domain 110 294 6.1E-28 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CDC59_RS03135 b504d825ae3ca830c8417f3268c50f47 483 Gene3D G3DSA:3.40.1190.10 94 314 7.7E-50 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CDC59_RS03135 b504d825ae3ca830c8417f3268c50f47 483 Pfam PF01225 Mur ligase family, catalytic domain 8 105 4.7E-26 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CDC59_RS03135 b504d825ae3ca830c8417f3268c50f47 483 Pfam PF02875 Mur ligase family, glutamate ligase domain 314 406 2.7E-17 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CDC59_RS03135 b504d825ae3ca830c8417f3268c50f47 483 Gene3D G3DSA:3.90.190.20 315 468 5.7E-36 T 29-03-2018 CDC59_RS00375 3b633c3be24b34e8fcfd026963bd3a32 522 Gene3D G3DSA:1.10.287.950 85 319 7.2E-17 T 29-03-2018 CDC59_RS00375 3b633c3be24b34e8fcfd026963bd3a32 522 Gene3D G3DSA:1.10.287.950 320 516 1.3E-48 T 29-03-2018 CDC59_RS00375 3b633c3be24b34e8fcfd026963bd3a32 522 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 324 479 1.2E-52 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CDC59_RS00375 3b633c3be24b34e8fcfd026963bd3a32 522 SUPERFAMILY SSF58104 233 513 2.75E-69 T 29-03-2018 CDC59_RS00375 3b633c3be24b34e8fcfd026963bd3a32 522 SMART SM00283 265 512 8.0E-85 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CDC59_RS00375 3b633c3be24b34e8fcfd026963bd3a32 522 Pfam PF12729 Four helix bundle sensory module for signal transduction 3 178 9.6E-11 T 29-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain CDC59_RS16055 bda1aa1dcde8ee520efa3522297afff9 461 Gene3D G3DSA:1.10.3080.10 18 455 1.7E-85 T 29-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 CDC59_RS16055 bda1aa1dcde8ee520efa3522297afff9 461 Hamap MF_01203 Voltage-gated ClC-type chloride channel ClcB [clcB]. 33 444 38.14 T 29-03-2018 IPR023790 Chloride channel, voltage-gated, ClcB GO:0006821|GO:0010447 CDC59_RS16055 bda1aa1dcde8ee520efa3522297afff9 461 SUPERFAMILY SSF81340 17 454 6.28E-100 T 29-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 CDC59_RS16055 bda1aa1dcde8ee520efa3522297afff9 461 Pfam PF00654 Voltage gated chloride channel 87 432 4.1E-81 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CDC59_RS16055 bda1aa1dcde8ee520efa3522297afff9 461 PRINTS PR00762 Chloride channel signature 348 368 5.3E-25 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CDC59_RS16055 bda1aa1dcde8ee520efa3522297afff9 461 PRINTS PR00762 Chloride channel signature 401 420 5.3E-25 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CDC59_RS16055 bda1aa1dcde8ee520efa3522297afff9 461 PRINTS PR00762 Chloride channel signature 185 204 5.3E-25 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CDC59_RS16055 bda1aa1dcde8ee520efa3522297afff9 461 PRINTS PR00762 Chloride channel signature 130 149 5.3E-25 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CDC59_RS16055 bda1aa1dcde8ee520efa3522297afff9 461 PRINTS PR00762 Chloride channel signature 383 399 5.3E-25 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CDC59_RS10325 d1e11e100231688bb52f70b7ffe558e8 393 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 391 4.5E-150 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CDC59_RS10325 d1e11e100231688bb52f70b7ffe558e8 393 Gene3D G3DSA:3.40.47.10 147 265 4.4E-30 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS10325 d1e11e100231688bb52f70b7ffe558e8 393 Gene3D G3DSA:3.40.47.10 1 141 3.2E-35 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS10325 d1e11e100231688bb52f70b7ffe558e8 393 SUPERFAMILY SSF53901 271 392 1.71E-44 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS10325 d1e11e100231688bb52f70b7ffe558e8 393 ProSitePatterns PS00737 Thiolases signature 2. 339 355 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CDC59_RS10325 d1e11e100231688bb52f70b7ffe558e8 393 Pfam PF02803 Thiolase, C-terminal domain 270 392 2.0E-54 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CDC59_RS10325 d1e11e100231688bb52f70b7ffe558e8 393 Pfam PF00108 Thiolase, N-terminal domain 4 262 2.0E-107 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CDC59_RS10325 d1e11e100231688bb52f70b7ffe558e8 393 ProSitePatterns PS00099 Thiolases active site. 374 387 - T 29-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CDC59_RS10325 d1e11e100231688bb52f70b7ffe558e8 393 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 84 102 - T 29-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CDC59_RS10325 d1e11e100231688bb52f70b7ffe558e8 393 PIRSF PIRSF000429 1 393 1.8E-134 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CDC59_RS10325 d1e11e100231688bb52f70b7ffe558e8 393 SUPERFAMILY SSF53901 3 270 6.54E-90 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS10325 d1e11e100231688bb52f70b7ffe558e8 393 Gene3D G3DSA:3.40.47.10 266 390 7.5E-36 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS00430 e5e28b37b2a2c39087c79e6deafc11ca 2359 SUPERFAMILY SSF48371 348 673 7.2E-11 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 CDC59_RS00430 e5e28b37b2a2c39087c79e6deafc11ca 2359 Gene3D G3DSA:3.30.460.10 1897 2049 0.038 T 29-03-2018 CDC59_RS00095 4fe8b6b22f93f44525a3ce594b019a1a 342 SUPERFAMILY SSF52283 1 140 1.76E-19 T 29-03-2018 CDC59_RS00095 4fe8b6b22f93f44525a3ce594b019a1a 342 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 115 300 1.2E-52 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CDC59_RS00095 4fe8b6b22f93f44525a3ce594b019a1a 342 SUPERFAMILY SSF51735 110 300 7.69E-50 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS00095 4fe8b6b22f93f44525a3ce594b019a1a 342 Gene3D G3DSA:3.40.50.720 1 118 8.2E-25 T 29-03-2018 CDC59_RS00095 4fe8b6b22f93f44525a3ce594b019a1a 342 Gene3D G3DSA:3.40.50.720 119 302 1.8E-47 T 29-03-2018 CDC59_RS00095 4fe8b6b22f93f44525a3ce594b019a1a 342 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 18 325 3.4E-15 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CDC59_RS03565 79ecc73d3cbf7dc357e60aa2e39c836e 219 Gene3D G3DSA:3.30.1450.10 61 134 2.1E-12 T 29-03-2018 CDC59_RS03565 79ecc73d3cbf7dc357e60aa2e39c836e 219 Hamap MF_00925 Outer membrane protein assembly factor BamE [bamE]. 24 163 29.15 T 29-03-2018 IPR026592 Outer membrane protein assembly factor BamE CDC59_RS03565 79ecc73d3cbf7dc357e60aa2e39c836e 219 Pfam PF04355 SmpA / OmlA family 61 130 3.3E-26 T 29-03-2018 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 CDC59_RS22315 280674c0098c064e3e481df483551970 540 SUPERFAMILY SSF51905 63 392 1.04E-25 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS22315 280674c0098c064e3e481df483551970 540 SUPERFAMILY SSF51905 497 539 1.04E-25 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS22315 280674c0098c064e3e481df483551970 540 Gene3D G3DSA:1.10.405.10 179 279 1.3E-26 T 29-03-2018 CDC59_RS22315 280674c0098c064e3e481df483551970 540 Pfam PF13450 NAD(P)-binding Rossmann-like domain 67 134 6.2E-10 T 29-03-2018 CDC59_RS22315 280674c0098c064e3e481df483551970 540 Gene3D G3DSA:3.50.50.60 9 137 6.2E-5 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS17455 9ae6243c3c0cfd1de6ce1e4fa0975adc 163 SUPERFAMILY SSF55729 1 159 1.08E-25 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDC59_RS17455 9ae6243c3c0cfd1de6ce1e4fa0975adc 163 Gene3D G3DSA:3.40.630.30 1 163 3.4E-29 T 29-03-2018 CDC59_RS17455 9ae6243c3c0cfd1de6ce1e4fa0975adc 163 Pfam PF00583 Acetyltransferase (GNAT) family 18 141 1.8E-12 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CDC59_RS01890 28b00ea27bb588d8f539204025a89f5d 1000 SUPERFAMILY SSF47226 838 851 1.73E-10 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CDC59_RS01890 28b00ea27bb588d8f539204025a89f5d 1000 SUPERFAMILY SSF47226 879 967 1.73E-10 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CDC59_RS01890 28b00ea27bb588d8f539204025a89f5d 1000 Gene3D G3DSA:1.20.120.160 828 995 4.9E-11 T 29-03-2018 CDC59_RS01890 28b00ea27bb588d8f539204025a89f5d 1000 SUPERFAMILY SSF55874 432 602 3.01E-45 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS01890 28b00ea27bb588d8f539204025a89f5d 1000 SMART SM00387 490 606 2.9E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS01890 28b00ea27bb588d8f539204025a89f5d 1000 Gene3D G3DSA:3.30.565.10 447 611 4.6E-48 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS01890 28b00ea27bb588d8f539204025a89f5d 1000 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 262 359 4.5E-7 T 29-03-2018 IPR000014 PAS domain CDC59_RS01890 28b00ea27bb588d8f539204025a89f5d 1000 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 109 222 1.9E-9 T 29-03-2018 IPR000014 PAS domain CDC59_RS01890 28b00ea27bb588d8f539204025a89f5d 1000 SUPERFAMILY SSF55785 91 217 2.27E-19 T 29-03-2018 IPR000014 PAS domain CDC59_RS01890 28b00ea27bb588d8f539204025a89f5d 1000 PRINTS PR00344 Bacterial sensor protein C-terminal signature 566 584 2.8E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS01890 28b00ea27bb588d8f539204025a89f5d 1000 PRINTS PR00344 Bacterial sensor protein C-terminal signature 590 603 2.8E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS01890 28b00ea27bb588d8f539204025a89f5d 1000 PRINTS PR00344 Bacterial sensor protein C-terminal signature 531 545 2.8E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS01890 28b00ea27bb588d8f539204025a89f5d 1000 PRINTS PR00344 Bacterial sensor protein C-terminal signature 549 559 2.8E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS01890 28b00ea27bb588d8f539204025a89f5d 1000 Pfam PF08447 PAS fold 267 348 2.6E-9 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 CDC59_RS01890 28b00ea27bb588d8f539204025a89f5d 1000 Pfam PF00512 His Kinase A (phospho-acceptor) domain 378 443 6.2E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS01890 28b00ea27bb588d8f539204025a89f5d 1000 Pfam PF00072 Response regulator receiver domain 740 855 1.7E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS01890 28b00ea27bb588d8f539204025a89f5d 1000 SMART SM00388 378 443 9.6E-22 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS01890 28b00ea27bb588d8f539204025a89f5d 1000 SUPERFAMILY SSF47384 365 444 2.55E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS01890 28b00ea27bb588d8f539204025a89f5d 1000 Pfam PF08448 PAS fold 111 220 9.8E-17 T 29-03-2018 IPR013656 PAS fold-4 CDC59_RS01890 28b00ea27bb588d8f539204025a89f5d 1000 Gene3D G3DSA:3.30.450.20 260 381 3.7E-18 T 29-03-2018 CDC59_RS01890 28b00ea27bb588d8f539204025a89f5d 1000 Gene3D G3DSA:3.30.450.20 83 223 6.8E-24 T 29-03-2018 CDC59_RS01890 28b00ea27bb588d8f539204025a89f5d 1000 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 491 603 1.7E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS01890 28b00ea27bb588d8f539204025a89f5d 1000 SMART SM00091 238 312 220.0 T 29-03-2018 IPR000014 PAS domain CDC59_RS01890 28b00ea27bb588d8f539204025a89f5d 1000 SMART SM00091 104 172 0.011 T 29-03-2018 IPR000014 PAS domain CDC59_RS01890 28b00ea27bb588d8f539204025a89f5d 1000 SUPERFAMILY SSF55785 224 356 3.66E-13 T 29-03-2018 IPR000014 PAS domain CDC59_RS01890 28b00ea27bb588d8f539204025a89f5d 1000 SMART SM00448 738 855 5.1E-33 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS01890 28b00ea27bb588d8f539204025a89f5d 1000 Gene3D G3DSA:1.10.287.130 382 439 2.4E-17 T 29-03-2018 CDC59_RS01890 28b00ea27bb588d8f539204025a89f5d 1000 Gene3D G3DSA:3.40.50.2300 735 823 2.0E-23 T 29-03-2018 CDC59_RS01890 28b00ea27bb588d8f539204025a89f5d 1000 SUPERFAMILY SSF52172 738 863 5.27E-34 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS01890 28b00ea27bb588d8f539204025a89f5d 1000 SMART SM00086 317 358 0.08 T 29-03-2018 IPR001610 PAC motif CDC59_RS01890 28b00ea27bb588d8f539204025a89f5d 1000 SMART SM00086 178 220 85.0 T 29-03-2018 IPR001610 PAC motif CDC59_RS06540 3e8b3b230d9a882dd595e90a09cf67d7 474 Pfam PF01979 Amidohydrolase family 73 438 2.4E-61 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CDC59_RS06540 3e8b3b230d9a882dd595e90a09cf67d7 474 SUPERFAMILY SSF51338 19 76 6.65E-18 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CDC59_RS06540 3e8b3b230d9a882dd595e90a09cf67d7 474 SUPERFAMILY SSF51338 389 452 6.65E-18 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CDC59_RS06540 3e8b3b230d9a882dd595e90a09cf67d7 474 Gene3D G3DSA:3.20.20.140 90 369 1.7E-56 T 29-03-2018 CDC59_RS06540 3e8b3b230d9a882dd595e90a09cf67d7 474 Gene3D G3DSA:2.30.40.10 370 466 6.2E-10 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CDC59_RS06540 3e8b3b230d9a882dd595e90a09cf67d7 474 SUPERFAMILY SSF51556 76 389 2.77E-97 T 29-03-2018 IPR032466 Metal-dependent hydrolase CDC59_RS06540 3e8b3b230d9a882dd595e90a09cf67d7 474 Gene3D G3DSA:2.30.40.10 2 89 9.8E-17 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CDC59_RS04205 808e37b7f5d2392b92a40cf8413d1c6e 177 Gene3D G3DSA:3.40.630.30 5 96 1.4E-22 T 29-03-2018 CDC59_RS04205 808e37b7f5d2392b92a40cf8413d1c6e 177 Gene3D G3DSA:3.40.630.30 97 165 7.9E-16 T 29-03-2018 CDC59_RS04205 808e37b7f5d2392b92a40cf8413d1c6e 177 SUPERFAMILY SSF55729 11 157 9.09E-36 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDC59_RS04205 808e37b7f5d2392b92a40cf8413d1c6e 177 Pfam PF00583 Acetyltransferase (GNAT) family 57 144 3.3E-17 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CDC59_RS04720 ac7f78bffb5c7bf23123ddc6c51daac4 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 134 162 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CDC59_RS04720 ac7f78bffb5c7bf23123ddc6c51daac4 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 73 84 3.0E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS04720 ac7f78bffb5c7bf23123ddc6c51daac4 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 166 3.0E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS04720 ac7f78bffb5c7bf23123ddc6c51daac4 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 135 3.0E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS04720 ac7f78bffb5c7bf23123ddc6c51daac4 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 1.7E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS04720 ac7f78bffb5c7bf23123ddc6c51daac4 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 1.7E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS04720 ac7f78bffb5c7bf23123ddc6c51daac4 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 1.7E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS04720 ac7f78bffb5c7bf23123ddc6c51daac4 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 1.7E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS04720 ac7f78bffb5c7bf23123ddc6c51daac4 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 1.7E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS04720 ac7f78bffb5c7bf23123ddc6c51daac4 250 SUPERFAMILY SSF51735 2 227 4.31E-58 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS04720 ac7f78bffb5c7bf23123ddc6c51daac4 250 Pfam PF00106 short chain dehydrogenase 2 187 2.7E-50 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS04720 ac7f78bffb5c7bf23123ddc6c51daac4 250 Gene3D G3DSA:3.40.50.720 1 235 2.1E-54 T 29-03-2018 CDC59_RS09900 4c7d2741acc24e4df534ece786a5623b 375 SUPERFAMILY SSF51230 2 87 3.27E-25 T 29-03-2018 IPR011053 Single hybrid motif CDC59_RS09900 4c7d2741acc24e4df534ece786a5623b 375 Gene3D G3DSA:3.90.1170.30 46 109 0.085 T 29-03-2018 CDC59_RS09900 4c7d2741acc24e4df534ece786a5623b 375 Pfam PF00364 Biotin-requiring enzyme 4 74 7.8E-20 T 29-03-2018 IPR000089 Biotin/lipoyl attachment CDC59_RS09900 4c7d2741acc24e4df534ece786a5623b 375 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 26 55 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CDC59_RS09900 4c7d2741acc24e4df534ece786a5623b 375 Gene3D G3DSA:3.30.559.10 158 372 2.2E-48 T 29-03-2018 CDC59_RS09900 4c7d2741acc24e4df534ece786a5623b 375 SUPERFAMILY SSF47005 118 158 2.35E-9 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CDC59_RS09900 4c7d2741acc24e4df534ece786a5623b 375 Pfam PF02817 e3 binding domain 120 155 1.3E-11 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CDC59_RS09900 4c7d2741acc24e4df534ece786a5623b 375 SUPERFAMILY SSF52777 170 372 5.34E-54 T 29-03-2018 CDC59_RS09900 4c7d2741acc24e4df534ece786a5623b 375 Gene3D G3DSA:3.90.1170.30 1 45 2.2E-13 T 29-03-2018 CDC59_RS09900 4c7d2741acc24e4df534ece786a5623b 375 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 170 367 2.2E-47 T 29-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CDC59_RS09900 4c7d2741acc24e4df534ece786a5623b 375 Gene3D G3DSA:4.10.320.10 110 157 1.3E-13 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CDC59_RS05855 f2762ddccdca537dc271f233976ac952 576 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 39 429 1.9E-22 T 29-03-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 CDC59_RS05855 f2762ddccdca537dc271f233976ac952 576 Gene3D G3DSA:3.40.720.10 36 569 7.8E-42 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CDC59_RS05855 f2762ddccdca537dc271f233976ac952 576 SUPERFAMILY SSF53649 32 113 3.33E-37 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CDC59_RS05855 f2762ddccdca537dc271f233976ac952 576 SUPERFAMILY SSF53649 340 555 3.33E-37 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CDC59_RS05855 f2762ddccdca537dc271f233976ac952 576 SUPERFAMILY SSF53649 182 288 3.33E-37 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CDC59_RS04010 e5507b4fa98c1b01ac7713c4ecce352e 681 Gene3D G3DSA:2.60.40.10 522 619 5.1E-8 T 29-03-2018 IPR013783 Immunoglobulin-like fold CDC59_RS04010 e5507b4fa98c1b01ac7713c4ecce352e 681 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 277 287 - T 29-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site CDC59_RS04010 e5507b4fa98c1b01ac7713c4ecce352e 681 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 188 199 - T 29-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CDC59_RS04010 e5507b4fa98c1b01ac7713c4ecce352e 681 Gene3D G3DSA:3.40.50.200 102 521 1.2E-62 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CDC59_RS04010 e5507b4fa98c1b01ac7713c4ecce352e 681 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 457 467 - T 29-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CDC59_RS04010 e5507b4fa98c1b01ac7713c4ecce352e 681 Pfam PF00082 Subtilase family 186 500 2.8E-36 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CDC59_RS04010 e5507b4fa98c1b01ac7713c4ecce352e 681 PRINTS PR00723 Subtilisin serine protease family (S8) signature 183 202 3.1E-14 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CDC59_RS04010 e5507b4fa98c1b01ac7713c4ecce352e 681 PRINTS PR00723 Subtilisin serine protease family (S8) signature 273 286 3.1E-14 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CDC59_RS04010 e5507b4fa98c1b01ac7713c4ecce352e 681 PRINTS PR00723 Subtilisin serine protease family (S8) signature 456 472 3.1E-14 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CDC59_RS04010 e5507b4fa98c1b01ac7713c4ecce352e 681 SUPERFAMILY SSF52743 270 523 5.11E-59 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CDC59_RS04010 e5507b4fa98c1b01ac7713c4ecce352e 681 SUPERFAMILY SSF52743 171 220 5.11E-59 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CDC59_RS04010 e5507b4fa98c1b01ac7713c4ecce352e 681 TIGRFAM TIGR03867 MprA_tail: MprA protease C-terminal rhombosortase-interaction domain 654 680 5.9E-9 T 29-03-2018 IPR021206 MprA protease C-terminal rhombosortase-interaction domain CDC59_RS18470 b7bcc12bd46fe6e39cbb63f5a009565f 366 ProSitePatterns PS00770 Aminotransferases class-IV signature. 241 271 - T 29-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 CDC59_RS18470 b7bcc12bd46fe6e39cbb63f5a009565f 366 Gene3D G3DSA:3.30.470.10 1 183 3.2E-63 T 29-03-2018 CDC59_RS18470 b7bcc12bd46fe6e39cbb63f5a009565f 366 Pfam PF01063 Amino-transferase class IV 78 320 5.9E-33 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CDC59_RS18470 b7bcc12bd46fe6e39cbb63f5a009565f 366 PIRSF PIRSF006468 7 365 1.4E-126 T 29-03-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 CDC59_RS18470 b7bcc12bd46fe6e39cbb63f5a009565f 366 Gene3D G3DSA:3.20.10.10 184 361 6.1E-52 T 29-03-2018 CDC59_RS18470 b7bcc12bd46fe6e39cbb63f5a009565f 366 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 52 363 4.1E-123 T 29-03-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 CDC59_RS18470 b7bcc12bd46fe6e39cbb63f5a009565f 366 SUPERFAMILY SSF56752 12 362 1.7E-114 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CDC59_RS08805 2c208086fea853e4fca19bd0c3cc18c7 862 SMART SM00382 197 342 3.1E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS08805 2c208086fea853e4fca19bd0c3cc18c7 862 SMART SM00382 600 742 6.0E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS08805 2c208086fea853e4fca19bd0c3cc18c7 862 Pfam PF07724 AAA domain (Cdc48 subfamily) 600 762 1.6E-54 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CDC59_RS08805 2c208086fea853e4fca19bd0c3cc18c7 862 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 293 305 - T 29-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 CDC59_RS08805 2c208086fea853e4fca19bd0c3cc18c7 862 SUPERFAMILY SSF81923 4 140 3.27E-37 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CDC59_RS08805 2c208086fea853e4fca19bd0c3cc18c7 862 SUPERFAMILY SSF52540 549 855 1.04E-85 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS08805 2c208086fea853e4fca19bd0c3cc18c7 862 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 68 4.4E-14 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CDC59_RS08805 2c208086fea853e4fca19bd0c3cc18c7 862 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 95 144 8.9E-9 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CDC59_RS08805 2c208086fea853e4fca19bd0c3cc18c7 862 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 768 846 2.7E-26 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CDC59_RS08805 2c208086fea853e4fca19bd0c3cc18c7 862 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 202 334 4.8E-14 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CDC59_RS08805 2c208086fea853e4fca19bd0c3cc18c7 862 Gene3D G3DSA:3.40.50.300 156 341 4.1E-25 T 29-03-2018 CDC59_RS08805 2c208086fea853e4fca19bd0c3cc18c7 862 Gene3D G3DSA:1.10.8.60 768 861 1.4E-23 T 29-03-2018 CDC59_RS08805 2c208086fea853e4fca19bd0c3cc18c7 862 Gene3D G3DSA:3.40.50.300 555 767 2.5E-53 T 29-03-2018 CDC59_RS08805 2c208086fea853e4fca19bd0c3cc18c7 862 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 857 0.0 T 29-03-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 CDC59_RS08805 2c208086fea853e4fca19bd0c3cc18c7 862 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 634 652 - T 29-03-2018 IPR028299 ClpA/B, conserved site 2 CDC59_RS08805 2c208086fea853e4fca19bd0c3cc18c7 862 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 678 696 1.3E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CDC59_RS08805 2c208086fea853e4fca19bd0c3cc18c7 862 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 604 622 1.3E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CDC59_RS08805 2c208086fea853e4fca19bd0c3cc18c7 862 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 649 667 1.3E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CDC59_RS08805 2c208086fea853e4fca19bd0c3cc18c7 862 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 711 725 1.3E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CDC59_RS08805 2c208086fea853e4fca19bd0c3cc18c7 862 SUPERFAMILY SSF52540 158 547 1.32E-99 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS08805 2c208086fea853e4fca19bd0c3cc18c7 862 Gene3D G3DSA:1.10.8.60 342 550 1.3E-44 T 29-03-2018 CDC59_RS08805 2c208086fea853e4fca19bd0c3cc18c7 862 SMART SM01086 768 857 4.3E-37 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CDC59_RS08805 2c208086fea853e4fca19bd0c3cc18c7 862 Gene3D G3DSA:1.10.1780.10 2 150 2.6E-32 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CDC59_RS11300 30d17909f1abe518556ed802ca31dc91 430 SUPERFAMILY SSF118215 6 405 1.01E-111 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CDC59_RS11300 30d17909f1abe518556ed802ca31dc91 430 PRINTS PR00173 Glutamate-aspartate symporter signature 148 170 1.6E-42 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CDC59_RS11300 30d17909f1abe518556ed802ca31dc91 430 PRINTS PR00173 Glutamate-aspartate symporter signature 196 215 1.6E-42 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CDC59_RS11300 30d17909f1abe518556ed802ca31dc91 430 PRINTS PR00173 Glutamate-aspartate symporter signature 51 71 1.6E-42 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CDC59_RS11300 30d17909f1abe518556ed802ca31dc91 430 PRINTS PR00173 Glutamate-aspartate symporter signature 331 350 1.6E-42 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CDC59_RS11300 30d17909f1abe518556ed802ca31dc91 430 PRINTS PR00173 Glutamate-aspartate symporter signature 358 378 1.6E-42 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CDC59_RS11300 30d17909f1abe518556ed802ca31dc91 430 PRINTS PR00173 Glutamate-aspartate symporter signature 81 106 1.6E-42 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CDC59_RS11300 30d17909f1abe518556ed802ca31dc91 430 PRINTS PR00173 Glutamate-aspartate symporter signature 4 24 1.6E-42 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CDC59_RS11300 30d17909f1abe518556ed802ca31dc91 430 PRINTS PR00173 Glutamate-aspartate symporter signature 296 322 1.6E-42 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CDC59_RS11300 30d17909f1abe518556ed802ca31dc91 430 Gene3D G3DSA:1.10.3860.10 1 411 2.4E-114 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CDC59_RS11300 30d17909f1abe518556ed802ca31dc91 430 Pfam PF00375 Sodium:dicarboxylate symporter family 6 403 5.5E-110 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CDC59_RS05970 4b034e8999bf25edf2888f2a46cea5d7 400 ProSitePatterns PS00737 Thiolases signature 2. 346 362 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CDC59_RS05970 4b034e8999bf25edf2888f2a46cea5d7 400 PIRSF PIRSF000429 1 400 1.2E-130 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CDC59_RS05970 4b034e8999bf25edf2888f2a46cea5d7 400 Pfam PF00108 Thiolase, N-terminal domain 5 268 1.5E-72 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CDC59_RS05970 4b034e8999bf25edf2888f2a46cea5d7 400 Gene3D G3DSA:3.40.47.10 1 271 2.8E-51 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS05970 4b034e8999bf25edf2888f2a46cea5d7 400 Gene3D G3DSA:3.40.47.10 272 397 3.2E-32 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS05970 4b034e8999bf25edf2888f2a46cea5d7 400 Pfam PF02803 Thiolase, C-terminal domain 276 399 7.9E-46 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CDC59_RS05970 4b034e8999bf25edf2888f2a46cea5d7 400 SUPERFAMILY SSF53901 276 399 3.55E-46 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS05970 4b034e8999bf25edf2888f2a46cea5d7 400 SUPERFAMILY SSF53901 4 275 1.4E-78 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS05970 4b034e8999bf25edf2888f2a46cea5d7 400 ProSitePatterns PS00099 Thiolases active site. 381 394 - T 29-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CDC59_RS05970 4b034e8999bf25edf2888f2a46cea5d7 400 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 398 4.5E-136 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CDC59_RS05970 4b034e8999bf25edf2888f2a46cea5d7 400 TIGRFAM TIGR02430 pcaF: 3-oxoadipyl-CoA thiolase 3 400 5.8E-223 T 29-03-2018 IPR012793 Beta-ketoadipyl CoA thiolase GO:0016747|GO:0019619 KEGG: 00250+2.3.1.17|KEGG: 00360+2.3.1.174|KEGG: 00362+2.3.1.174|MetaCyc: PWY-1361|MetaCyc: PWY-2361|MetaCyc: PWY-6185 CDC59_RS06795 d44ebf07bdbbb16555d356906d04cc71 334 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 29 315 1.0E-62 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CDC59_RS06795 d44ebf07bdbbb16555d356906d04cc71 334 Gene3D G3DSA:3.40.50.1100 40 148 4.0E-28 T 29-03-2018 CDC59_RS06795 d44ebf07bdbbb16555d356906d04cc71 334 SUPERFAMILY SSF53686 18 324 2.23E-72 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CDC59_RS06795 d44ebf07bdbbb16555d356906d04cc71 334 Gene3D G3DSA:3.40.50.1100 149 327 2.0E-27 T 29-03-2018 CDC59_RS06745 e8afc9dbfab161009a891e993a0b370f 313 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 313 65.747 T 29-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 CDC59_RS06745 e8afc9dbfab161009a891e993a0b370f 313 Pfam PF03186 CobD/Cbib protein 28 256 8.8E-25 T 29-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 CDC59_RS20985 a60a98f79f1425b867f120d640f3bfee 489 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 258 265 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CDC59_RS20985 a60a98f79f1425b867f120d640f3bfee 489 Gene3D G3DSA:3.40.309.10 277 469 4.8E-74 T 29-03-2018 CDC59_RS20985 a60a98f79f1425b867f120d640f3bfee 489 SUPERFAMILY SSF53720 11 485 3.01E-171 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CDC59_RS20985 a60a98f79f1425b867f120d640f3bfee 489 Gene3D G3DSA:3.40.605.10 8 276 3.7E-102 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CDC59_RS20985 a60a98f79f1425b867f120d640f3bfee 489 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 286 297 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CDC59_RS20985 a60a98f79f1425b867f120d640f3bfee 489 TIGRFAM TIGR01780 SSADH: succinate-semialdehyde dehydrogenase 31 481 1.8E-204 T 29-03-2018 IPR010102 Succinate semialdehyde dehydrogenase GO:0009013|GO:0009450|GO:0055114 Reactome: R-HSA-916853 CDC59_RS20985 a60a98f79f1425b867f120d640f3bfee 489 Pfam PF00171 Aldehyde dehydrogenase family 21 483 1.6E-170 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CDC59_RS16700 65bb65fc657ce484422128eda11d867e 147 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 33 139 5.7E-15 T 29-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 CDC59_RS16700 65bb65fc657ce484422128eda11d867e 147 SUPERFAMILY SSF54637 4 143 1.97E-24 T 29-03-2018 IPR029069 HotDog domain CDC59_RS16700 65bb65fc657ce484422128eda11d867e 147 Gene3D G3DSA:3.10.129.10 5 143 3.2E-21 T 29-03-2018 CDC59_RS16700 65bb65fc657ce484422128eda11d867e 147 Pfam PF03061 Thioesterase superfamily 52 127 3.7E-11 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CDC59_RS14295 9b04bbe74d8837ba2fda5bd7bc281dc6 289 SUPERFAMILY SSF55060 165 286 2.97E-31 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain CDC59_RS14295 9b04bbe74d8837ba2fda5bd7bc281dc6 289 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 11 284 1.7E-73 T 29-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CDC59_RS14295 9b04bbe74d8837ba2fda5bd7bc281dc6 289 Pfam PF08544 GHMP kinases C terminal 217 268 2.7E-6 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain CDC59_RS14295 9b04bbe74d8837ba2fda5bd7bc281dc6 289 Pfam PF00288 GHMP kinases N terminal domain 91 148 4.1E-10 T 29-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CDC59_RS14295 9b04bbe74d8837ba2fda5bd7bc281dc6 289 Gene3D G3DSA:3.30.230.10 9 164 2.8E-47 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CDC59_RS14295 9b04bbe74d8837ba2fda5bd7bc281dc6 289 SUPERFAMILY SSF54211 12 163 3.42E-45 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CDC59_RS14295 9b04bbe74d8837ba2fda5bd7bc281dc6 289 Gene3D G3DSA:3.30.70.890 166 289 1.1E-26 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain CDC59_RS14295 9b04bbe74d8837ba2fda5bd7bc281dc6 289 PIRSF PIRSF010376 8 288 3.7E-88 T 29-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CDC59_RS14295 9b04bbe74d8837ba2fda5bd7bc281dc6 289 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 9 276 32.54 T 29-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CDC59_RS09755 b91f96e45038ef05ab9c11fd0f06eda4 320 Gene3D G3DSA:1.20.1050.10 100 219 6.1E-19 T 29-03-2018 CDC59_RS09755 b91f96e45038ef05ab9c11fd0f06eda4 320 SUPERFAMILY SSF52833 4 95 3.71E-17 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS09755 b91f96e45038ef05ab9c11fd0f06eda4 320 SUPERFAMILY SSF47616 82 219 7.5E-13 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like CDC59_RS09755 b91f96e45038ef05ab9c11fd0f06eda4 320 Pfam PF13410 Glutathione S-transferase, C-terminal domain 151 216 8.4E-11 T 29-03-2018 CDC59_RS09755 b91f96e45038ef05ab9c11fd0f06eda4 320 Gene3D G3DSA:3.40.30.10 1 99 2.0E-12 T 29-03-2018 CDC59_RS09755 b91f96e45038ef05ab9c11fd0f06eda4 320 Pfam PF13417 Glutathione S-transferase, N-terminal domain 6 78 9.3E-13 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CDC59_RS11770 e3ce0b03e652bb1170ec6e52714fb977 163 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 11 160 28.121 T 29-03-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS11770 e3ce0b03e652bb1170ec6e52714fb977 163 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 103 114 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CDC59_RS11770 e3ce0b03e652bb1170ec6e52714fb977 163 Gene3D G3DSA:3.30.70.20 108 157 3.3E-7 T 29-03-2018 CDC59_RS11770 e3ce0b03e652bb1170ec6e52714fb977 163 Gene3D G3DSA:3.30.70.20 75 107 2.4E-14 T 29-03-2018 CDC59_RS11770 e3ce0b03e652bb1170ec6e52714fb977 163 Gene3D G3DSA:3.30.70.20 32 74 8.1E-7 T 29-03-2018 CDC59_RS11770 e3ce0b03e652bb1170ec6e52714fb977 163 Pfam PF12838 4Fe-4S dicluster domain 63 117 1.2E-12 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CDC59_RS11770 e3ce0b03e652bb1170ec6e52714fb977 163 SUPERFAMILY SSF54862 37 146 3.52E-26 T 29-03-2018 CDC59_RS11770 e3ce0b03e652bb1170ec6e52714fb977 163 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 20 141 5.5E-46 T 29-03-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS22715 6a94f9e5fcb7505bde15a89b1077b767 261 Pfam PF00196 Bacterial regulatory proteins, luxR family 195 246 3.0E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS22715 6a94f9e5fcb7505bde15a89b1077b767 261 SMART SM00421 192 249 1.0E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS22715 6a94f9e5fcb7505bde15a89b1077b767 261 ProSitePatterns PS00622 LuxR-type HTH domain signature. 209 236 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS22715 6a94f9e5fcb7505bde15a89b1077b767 261 SUPERFAMILY SSF46894 184 248 1.43E-13 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CDC59_RS22715 6a94f9e5fcb7505bde15a89b1077b767 261 Gene3D G3DSA:1.10.10.10 142 257 1.9E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS22715 6a94f9e5fcb7505bde15a89b1077b767 261 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 195 209 3.0E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS22715 6a94f9e5fcb7505bde15a89b1077b767 261 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 225 237 3.0E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS22715 6a94f9e5fcb7505bde15a89b1077b767 261 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 209 225 3.0E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS11180 2c7c4da25c3bca60a1d0d746f5816787 332 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS11180 2c7c4da25c3bca60a1d0d746f5816787 332 SMART SM00382 36 243 7.7E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS11180 2c7c4da25c3bca60a1d0d746f5816787 332 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 235 319 4.4E-23 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CDC59_RS11180 2c7c4da25c3bca60a1d0d746f5816787 332 Pfam PF00005 ABC transporter 28 185 2.0E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS11180 2c7c4da25c3bca60a1d0d746f5816787 332 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 237 301 1.1E-20 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CDC59_RS11180 2c7c4da25c3bca60a1d0d746f5816787 332 Gene3D G3DSA:3.40.50.300 5 328 1.4E-73 T 29-03-2018 CDC59_RS11180 2c7c4da25c3bca60a1d0d746f5816787 332 SUPERFAMILY SSF52540 36 302 3.47E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS06810 c40ad13859a649e121004470f4758c1a 432 Pfam PF12867 DinB superfamily 34 174 3.5E-5 T 29-03-2018 IPR024775 DinB-like domain CDC59_RS06810 c40ad13859a649e121004470f4758c1a 432 Gene3D G3DSA:3.90.1580.10 203 356 4.8E-38 T 29-03-2018 CDC59_RS06810 c40ad13859a649e121004470f4758c1a 432 Gene3D G3DSA:3.90.1580.10 357 431 3.7E-7 T 29-03-2018 CDC59_RS06810 c40ad13859a649e121004470f4758c1a 432 Pfam PF03781 Sulfatase-modifying factor enzyme 1 209 353 2.2E-29 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 CDC59_RS06810 c40ad13859a649e121004470f4758c1a 432 TIGRFAM TIGR03440 egtB_TIGR03440: ergothioneine biosynthesis protein EgtB 30 430 1.3E-127 T 29-03-2018 IPR017806 Ergothioneine biosynthesis protein EgtB GO:0052699 CDC59_RS06810 c40ad13859a649e121004470f4758c1a 432 SUPERFAMILY SSF56436 210 430 1.05E-53 T 29-03-2018 IPR016187 C-type lectin fold CDC59_RS22290 8092482c31b8dc88a0fdd9f4936d2921 289 Gene3D G3DSA:1.10.3470.10 1 279 2.3E-47 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CDC59_RS22290 8092482c31b8dc88a0fdd9f4936d2921 289 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 274 5.5E-36 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CDC59_RS00010 a26dd39bbb145db67178e616eb9c110c 143 Pfam PF00825 Ribonuclease P 7 97 3.1E-22 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CDC59_RS00010 a26dd39bbb145db67178e616eb9c110c 143 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 14 87 3.0E-35 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CDC59_RS00010 a26dd39bbb145db67178e616eb9c110c 143 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 11 87 3.5E-16 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CDC59_RS00010 a26dd39bbb145db67178e616eb9c110c 143 SUPERFAMILY SSF54211 5 99 6.57E-22 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CDC59_RS00010 a26dd39bbb145db67178e616eb9c110c 143 Gene3D G3DSA:3.30.230.10 1 122 1.9E-27 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CDC59_RS00010 a26dd39bbb145db67178e616eb9c110c 143 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 6 121 15.593 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CDC59_RS16200 33144bf920510c0f0d8aec5a360cffca 539 ProSitePatterns PS00455 Putative AMP-binding domain signature. 199 210 - T 29-03-2018 IPR020845 AMP-binding, conserved site CDC59_RS16200 33144bf920510c0f0d8aec5a360cffca 539 SUPERFAMILY SSF56801 14 535 2.22E-131 T 29-03-2018 CDC59_RS16200 33144bf920510c0f0d8aec5a360cffca 539 Gene3D G3DSA:3.30.300.30 436 538 3.1E-26 T 29-03-2018 CDC59_RS16200 33144bf920510c0f0d8aec5a360cffca 539 Pfam PF00501 AMP-binding enzyme 46 440 1.3E-77 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CDC59_RS16200 33144bf920510c0f0d8aec5a360cffca 539 Pfam PF13193 AMP-binding enzyme C-terminal domain 449 527 1.4E-21 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CDC59_RS16200 33144bf920510c0f0d8aec5a360cffca 539 Gene3D G3DSA:3.40.50.980 205 353 8.0E-36 T 29-03-2018 CDC59_RS16200 33144bf920510c0f0d8aec5a360cffca 539 Gene3D G3DSA:3.40.50.980 34 204 8.2E-35 T 29-03-2018 CDC59_RS16200 33144bf920510c0f0d8aec5a360cffca 539 Gene3D G3DSA:2.30.38.10 354 433 1.2E-15 T 29-03-2018 CDC59_RS07005 70b2a030dc130fdf841079da03792398 640 PIRSF PIRSF002583 2 640 3.4E-211 T 29-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 CDC59_RS07005 70b2a030dc130fdf841079da03792398 640 SUPERFAMILY SSF110942 520 639 2.62E-34 T 29-03-2018 CDC59_RS07005 70b2a030dc130fdf841079da03792398 640 ProSitePatterns PS00298 Heat shock hsp90 proteins family signature. 26 35 - T 29-03-2018 IPR019805 Heat shock protein Hsp90, conserved site GO:0005524|GO:0006457|GO:0006950|GO:0051082 CDC59_RS07005 70b2a030dc130fdf841079da03792398 640 SMART SM00387 28 185 3.7E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS07005 70b2a030dc130fdf841079da03792398 640 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 28 183 2.1E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS07005 70b2a030dc130fdf841079da03792398 640 SUPERFAMILY SSF54211 235 494 5.69E-94 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CDC59_RS07005 70b2a030dc130fdf841079da03792398 640 Hamap MF_00505 Chaperone protein HtpG [htpG]. 3 640 32.711 T 29-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 CDC59_RS07005 70b2a030dc130fdf841079da03792398 640 Gene3D G3DSA:3.30.565.10 2 228 2.4E-55 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS07005 70b2a030dc130fdf841079da03792398 640 PRINTS PR00775 90kDa heat shock protein signature 76 93 2.6E-62 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CDC59_RS07005 70b2a030dc130fdf841079da03792398 640 PRINTS PR00775 90kDa heat shock protein signature 121 143 2.6E-62 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CDC59_RS07005 70b2a030dc130fdf841079da03792398 640 PRINTS PR00775 90kDa heat shock protein signature 173 190 2.6E-62 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CDC59_RS07005 70b2a030dc130fdf841079da03792398 640 PRINTS PR00775 90kDa heat shock protein signature 6 26 2.6E-62 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CDC59_RS07005 70b2a030dc130fdf841079da03792398 640 PRINTS PR00775 90kDa heat shock protein signature 94 111 2.6E-62 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CDC59_RS07005 70b2a030dc130fdf841079da03792398 640 PRINTS PR00775 90kDa heat shock protein signature 191 209 2.6E-62 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CDC59_RS07005 70b2a030dc130fdf841079da03792398 640 PRINTS PR00775 90kDa heat shock protein signature 27 49 2.6E-62 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CDC59_RS07005 70b2a030dc130fdf841079da03792398 640 SUPERFAMILY SSF55874 5 217 1.14E-66 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS07005 70b2a030dc130fdf841079da03792398 640 Pfam PF00183 Hsp90 protein 218 639 9.5E-127 T 29-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 CDC59_RS00445 3b133bf7b89a8d5823443155d6879807 401 Pfam PF00175 Oxidoreductase NAD-binding domain 268 373 2.9E-8 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CDC59_RS00445 3b133bf7b89a8d5823443155d6879807 401 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 360 368 1.6E-5 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CDC59_RS00445 3b133bf7b89a8d5823443155d6879807 401 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 182 192 1.6E-5 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CDC59_RS00445 3b133bf7b89a8d5823443155d6879807 401 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 231 240 1.6E-5 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CDC59_RS00445 3b133bf7b89a8d5823443155d6879807 401 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 267 286 1.6E-5 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CDC59_RS00445 3b133bf7b89a8d5823443155d6879807 401 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 202 209 1.6E-5 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CDC59_RS00445 3b133bf7b89a8d5823443155d6879807 401 Pfam PF00042 Globin 9 102 1.3E-7 T 29-03-2018 IPR000971 Globin GO:0020037 CDC59_RS00445 3b133bf7b89a8d5823443155d6879807 401 Gene3D G3DSA:2.40.30.10 157 247 1.4E-23 T 29-03-2018 CDC59_RS00445 3b133bf7b89a8d5823443155d6879807 401 PRINTS PR00410 Phenol hydroxylase reductase family signature 182 194 4.0E-6 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CDC59_RS00445 3b133bf7b89a8d5823443155d6879807 401 PRINTS PR00410 Phenol hydroxylase reductase family signature 267 286 4.0E-6 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CDC59_RS00445 3b133bf7b89a8d5823443155d6879807 401 PRINTS PR00410 Phenol hydroxylase reductase family signature 360 368 4.0E-6 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CDC59_RS00445 3b133bf7b89a8d5823443155d6879807 401 SUPERFAMILY SSF46458 2 142 1.15E-37 T 29-03-2018 IPR009050 Globin-like CDC59_RS00445 3b133bf7b89a8d5823443155d6879807 401 Gene3D G3DSA:1.10.490.10 1 156 2.4E-36 T 29-03-2018 CDC59_RS00445 3b133bf7b89a8d5823443155d6879807 401 Pfam PF00970 Oxidoreductase FAD-binding domain 155 256 1.0E-6 T 29-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CDC59_RS00445 3b133bf7b89a8d5823443155d6879807 401 SUPERFAMILY SSF52343 247 390 1.7E-29 T 29-03-2018 CDC59_RS00445 3b133bf7b89a8d5823443155d6879807 401 Gene3D G3DSA:3.40.50.80 248 389 4.1E-22 T 29-03-2018 CDC59_RS00445 3b133bf7b89a8d5823443155d6879807 401 SUPERFAMILY SSF63380 149 256 3.57E-26 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CDC59_RS00560 aa06f41d5c94abc42e6bd1ec15b4c46f 453 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS00560 aa06f41d5c94abc42e6bd1ec15b4c46f 453 SUPERFAMILY SSF52540 8 247 1.2E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS00560 aa06f41d5c94abc42e6bd1ec15b4c46f 453 SMART SM00382 38 220 1.5E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS00560 aa06f41d5c94abc42e6bd1ec15b4c46f 453 Gene3D G3DSA:3.40.50.300 4 231 1.4E-57 T 29-03-2018 CDC59_RS00560 aa06f41d5c94abc42e6bd1ec15b4c46f 453 Pfam PF09821 C-terminal AAA-associated domain 304 421 1.1E-36 T 29-03-2018 IPR018632 C-terminal AAA-associated domain CDC59_RS00560 aa06f41d5c94abc42e6bd1ec15b4c46f 453 Pfam PF00005 ABC transporter 29 168 4.2E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS06405 719c453ce0293c97e4003986237a2c5f 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 4 27 5.8E-47 T 29-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CDC59_RS06405 719c453ce0293c97e4003986237a2c5f 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 132 148 5.8E-47 T 29-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CDC59_RS06405 719c453ce0293c97e4003986237a2c5f 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 62 74 5.8E-47 T 29-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CDC59_RS06405 719c453ce0293c97e4003986237a2c5f 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 162 174 5.8E-47 T 29-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CDC59_RS06405 719c453ce0293c97e4003986237a2c5f 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 80 100 5.8E-47 T 29-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CDC59_RS06405 719c453ce0293c97e4003986237a2c5f 215 SUPERFAMILY SSF53182 1 214 4.71E-74 T 29-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like CDC59_RS06405 719c453ce0293c97e4003986237a2c5f 215 ProSitePatterns PS01334 Pyrrolidone-carboxylate peptidase cysteine active site. 130 144 - T 29-03-2018 IPR033694 Pyroglutamyl peptidase I, Cys active site CDC59_RS06405 719c453ce0293c97e4003986237a2c5f 215 PIRSF PIRSF015592 1 213 3.9E-87 T 29-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CDC59_RS06405 719c453ce0293c97e4003986237a2c5f 215 Gene3D G3DSA:3.40.630.20 2 215 3.0E-66 T 29-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like CDC59_RS06405 719c453ce0293c97e4003986237a2c5f 215 Pfam PF01470 Pyroglutamyl peptidase 4 202 2.3E-84 T 29-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like CDC59_RS06405 719c453ce0293c97e4003986237a2c5f 215 Hamap MF_00417 Pyrrolidone-carboxylate peptidase [pcp]. 2 201 40.698 T 29-03-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 CDC59_RS06405 719c453ce0293c97e4003986237a2c5f 215 TIGRFAM TIGR00504 pyro_pdase: pyroglutamyl-peptidase I 4 215 7.1E-93 T 29-03-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 CDC59_RS02330 1ec06ce4b24a2c6c6b5b0704ed31bc6c 143 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 142 7.2E-29 T 29-03-2018 IPR021131 Ribosomal protein L18e/L15P CDC59_RS02330 1ec06ce4b24a2c6c6b5b0704ed31bc6c 143 Gene3D G3DSA:3.100.10.10 42 143 1.5E-22 T 29-03-2018 CDC59_RS02330 1ec06ce4b24a2c6c6b5b0704ed31bc6c 143 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 142 1.2E-46 T 29-03-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS02330 1ec06ce4b24a2c6c6b5b0704ed31bc6c 143 SUPERFAMILY SSF52080 4 141 1.96E-44 T 29-03-2018 IPR021131 Ribosomal protein L18e/L15P CDC59_RS02330 1ec06ce4b24a2c6c6b5b0704ed31bc6c 143 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 143 19.426 T 29-03-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 CDC59_RS02330 1ec06ce4b24a2c6c6b5b0704ed31bc6c 143 ProSitePatterns PS00475 Ribosomal protein L15 signature. 109 139 - T 29-03-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS07390 750f6794886dd80841ab930e70db82c9 147 SUPERFAMILY SSF56214 14 140 1.14E-27 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CDC59_RS07390 750f6794886dd80841ab930e70db82c9 147 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 15 141 25.908 T 29-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CDC59_RS07390 750f6794886dd80841ab930e70db82c9 147 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 16 136 2.9E-18 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CDC59_RS07390 750f6794886dd80841ab930e70db82c9 147 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 13 141 2.7E-28 T 29-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CDC59_RS07390 750f6794886dd80841ab930e70db82c9 147 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 14 139 1.2E-20 T 29-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CDC59_RS07390 750f6794886dd80841ab930e70db82c9 147 Gene3D G3DSA:3.90.470.20 10 145 2.3E-30 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CDC59_RS07390 750f6794886dd80841ab930e70db82c9 147 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 20 107 3.0E-44 T 29-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CDC59_RS10880 2b319c3ec57f8a164e115af6e7fda4b4 278 Pfam PF13444 Acetyltransferase (GNAT) domain 60 161 7.6E-36 T 29-03-2018 CDC59_RS10880 2b319c3ec57f8a164e115af6e7fda4b4 278 Gene3D G3DSA:3.40.630.30 42 227 4.4E-36 T 29-03-2018 CDC59_RS10880 2b319c3ec57f8a164e115af6e7fda4b4 278 SUPERFAMILY SSF55729 42 251 1.52E-42 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDC59_RS12505 3bfa45843cb311e63b66f269924fa034 551 Gene3D G3DSA:3.30.450.20 208 317 1.2E-6 T 29-03-2018 CDC59_RS12505 3bfa45843cb311e63b66f269924fa034 551 Gene3D G3DSA:3.30.70.270 382 551 1.1E-48 T 29-03-2018 CDC59_RS12505 3bfa45843cb311e63b66f269924fa034 551 Gene3D G3DSA:3.30.450.20 45 207 1.7E-14 T 29-03-2018 CDC59_RS12505 3bfa45843cb311e63b66f269924fa034 551 SUPERFAMILY SSF103190 110 221 1.14E-7 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CDC59_RS12505 3bfa45843cb311e63b66f269924fa034 551 SUPERFAMILY SSF55073 397 548 6.91E-43 T 29-03-2018 IPR029787 Nucleotide cyclase CDC59_RS12505 3bfa45843cb311e63b66f269924fa034 551 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 389 548 6.3E-44 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS12505 3bfa45843cb311e63b66f269924fa034 551 Pfam PF02743 Cache domain 57 260 4.8E-14 T 29-03-2018 IPR033479 Double Cache domain 1 CDC59_RS12505 3bfa45843cb311e63b66f269924fa034 551 Pfam PF00990 Diguanylate cyclase, GGDEF domain 392 547 1.8E-41 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS12505 3bfa45843cb311e63b66f269924fa034 551 SMART SM00267 381 551 8.2E-56 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS07180 1a8eaca380fdf0bd346b0444ce7de82c 64 Gene3D G3DSA:1.10.10.600 1 62 3.0E-30 T 29-03-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 CDC59_RS07180 1a8eaca380fdf0bd346b0444ce7de82c 64 SUPERFAMILY SSF140319 1 62 5.49E-25 T 29-03-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 CDC59_RS07180 1a8eaca380fdf0bd346b0444ce7de82c 64 Pfam PF04384 Iron-sulphur cluster assembly 1 64 4.2E-30 T 29-03-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 CDC59_RS07180 1a8eaca380fdf0bd346b0444ce7de82c 64 TIGRFAM TIGR03412 iscX_yfhJ: FeS assembly protein IscX 2 64 1.4E-32 T 29-03-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 CDC59_RS07180 1a8eaca380fdf0bd346b0444ce7de82c 64 PIRSF PIRSF039003 1 64 6.5E-33 T 29-03-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 CDC59_RS23795 995f10a26a12311e7d392a818b48b055 1054 Gene3D G3DSA:3.30.2090.10 723 809 3.1E-18 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS23795 995f10a26a12311e7d392a818b48b055 1054 Gene3D G3DSA:1.20.1640.10 286 517 5.7E-44 T 29-03-2018 CDC59_RS23795 995f10a26a12311e7d392a818b48b055 1054 Gene3D G3DSA:1.20.1640.10 828 1048 1.2E-33 T 29-03-2018 CDC59_RS23795 995f10a26a12311e7d392a818b48b055 1054 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 1 1042 0.0 T 29-03-2018 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 CDC59_RS23795 995f10a26a12311e7d392a818b48b055 1054 SUPERFAMILY SSF82693 46 127 2.14E-19 T 29-03-2018 CDC59_RS23795 995f10a26a12311e7d392a818b48b055 1054 SUPERFAMILY SSF82693 271 328 2.88E-22 T 29-03-2018 CDC59_RS23795 995f10a26a12311e7d392a818b48b055 1054 SUPERFAMILY SSF82693 137 184 2.88E-22 T 29-03-2018 CDC59_RS23795 995f10a26a12311e7d392a818b48b055 1054 Gene3D G3DSA:3.30.70.1430 567 665 1.4E-7 T 29-03-2018 CDC59_RS23795 995f10a26a12311e7d392a818b48b055 1054 Gene3D G3DSA:3.30.2090.10 183 271 1.3E-16 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS23795 995f10a26a12311e7d392a818b48b055 1054 SUPERFAMILY SSF82714 185 270 3.01E-17 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS23795 995f10a26a12311e7d392a818b48b055 1054 PRINTS PR00702 Acriflavin resistance protein family signature 334 357 6.9E-22 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS23795 995f10a26a12311e7d392a818b48b055 1054 PRINTS PR00702 Acriflavin resistance protein family signature 361 382 6.9E-22 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS23795 995f10a26a12311e7d392a818b48b055 1054 PRINTS PR00702 Acriflavin resistance protein family signature 389 413 6.9E-22 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS23795 995f10a26a12311e7d392a818b48b055 1054 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 6.9E-22 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS23795 995f10a26a12311e7d392a818b48b055 1054 PRINTS PR00702 Acriflavin resistance protein family signature 552 569 6.9E-22 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS23795 995f10a26a12311e7d392a818b48b055 1054 SUPERFAMILY SSF82866 295 505 5.75E-38 T 29-03-2018 CDC59_RS23795 995f10a26a12311e7d392a818b48b055 1054 SUPERFAMILY SSF82866 806 1038 1.83E-47 T 29-03-2018 CDC59_RS23795 995f10a26a12311e7d392a818b48b055 1054 Gene3D G3DSA:3.30.70.1430 45 138 1.1E-18 T 29-03-2018 CDC59_RS23795 995f10a26a12311e7d392a818b48b055 1054 Pfam PF00873 AcrB/AcrD/AcrF family 8 1035 3.7E-233 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS23795 995f10a26a12311e7d392a818b48b055 1054 SUPERFAMILY SSF82714 723 806 5.62E-17 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS20140 1a0448f93ae18c297e95dde9e71a9363 245 SMART SM00862 149 225 6.4E-16 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDC59_RS20140 1a0448f93ae18c297e95dde9e71a9363 245 SUPERFAMILY SSF46894 126 226 6.05E-22 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CDC59_RS20140 1a0448f93ae18c297e95dde9e71a9363 245 Gene3D G3DSA:3.40.50.2300 1 123 3.7E-12 T 29-03-2018 CDC59_RS20140 1a0448f93ae18c297e95dde9e71a9363 245 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 225 2.9E-19 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDC59_RS20140 1a0448f93ae18c297e95dde9e71a9363 245 Gene3D G3DSA:1.10.10.10 124 231 1.2E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS20140 1a0448f93ae18c297e95dde9e71a9363 245 SUPERFAMILY SSF52172 9 129 2.34E-11 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS17125 12f99da6979ed5170d382bf03286d3d1 210 SMART SM00421 146 203 3.1E-16 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS17125 12f99da6979ed5170d382bf03286d3d1 210 SUPERFAMILY SSF46894 140 208 2.86E-17 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CDC59_RS17125 12f99da6979ed5170d382bf03286d3d1 210 Gene3D G3DSA:1.10.10.10 127 209 5.5E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS17125 12f99da6979ed5170d382bf03286d3d1 210 SMART SM00448 2 115 0.0028 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS17125 12f99da6979ed5170d382bf03286d3d1 210 SUPERFAMILY SSF52172 1 133 1.57E-15 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS17125 12f99da6979ed5170d382bf03286d3d1 210 Pfam PF00072 Response regulator receiver domain 4 115 1.9E-9 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS17125 12f99da6979ed5170d382bf03286d3d1 210 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 202 1.2E-16 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS17125 12f99da6979ed5170d382bf03286d3d1 210 Gene3D G3DSA:3.40.50.2300 1 126 4.2E-18 T 29-03-2018 CDC59_RS17125 12f99da6979ed5170d382bf03286d3d1 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 1.2E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS17125 12f99da6979ed5170d382bf03286d3d1 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 1.2E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS17125 12f99da6979ed5170d382bf03286d3d1 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 1.2E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS01415 daf839705750f114b38607bfc9e45cbe 2469 Pfam PF13193 AMP-binding enzyme C-terminal domain 2040 2115 1.2E-16 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CDC59_RS01415 daf839705750f114b38607bfc9e45cbe 2469 Pfam PF13193 AMP-binding enzyme C-terminal domain 969 1044 6.0E-13 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CDC59_RS01415 daf839705750f114b38607bfc9e45cbe 2469 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1652 2056 1.5E-132 T 29-03-2018 IPR010071 Amino acid adenylation domain CDC59_RS01415 daf839705750f114b38607bfc9e45cbe 2469 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 569 985 3.6E-140 T 29-03-2018 IPR010071 Amino acid adenylation domain CDC59_RS01415 daf839705750f114b38607bfc9e45cbe 2469 SMART SM00824 Thioesterase 2230 2465 4.8E-5 T 29-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 CDC59_RS01415 daf839705750f114b38607bfc9e45cbe 2469 SUPERFAMILY SSF53474 2207 2469 3.92E-51 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS01415 daf839705750f114b38607bfc9e45cbe 2469 SUPERFAMILY SSF52777 153 255 1.22E-23 T 29-03-2018 CDC59_RS01415 daf839705750f114b38607bfc9e45cbe 2469 ProSitePatterns PS00455 Putative AMP-binding domain signature. 696 707 - T 29-03-2018 IPR020845 AMP-binding, conserved site CDC59_RS01415 daf839705750f114b38607bfc9e45cbe 2469 SUPERFAMILY SSF56801 1592 2152 8.37E-162 T 29-03-2018 CDC59_RS01415 daf839705750f114b38607bfc9e45cbe 2469 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1095 1110 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CDC59_RS01415 daf839705750f114b38607bfc9e45cbe 2469 Pfam PF00550 Phosphopantetheine attachment site 2142 2205 2.3E-16 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS01415 daf839705750f114b38607bfc9e45cbe 2469 Pfam PF00550 Phosphopantetheine attachment site 1073 1134 4.7E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS01415 daf839705750f114b38607bfc9e45cbe 2469 Gene3D G3DSA:2.30.38.10 1941 2022 1.7E-26 T 29-03-2018 CDC59_RS01415 daf839705750f114b38607bfc9e45cbe 2469 Gene3D G3DSA:2.30.38.10 868 951 1.1E-24 T 29-03-2018 CDC59_RS01415 daf839705750f114b38607bfc9e45cbe 2469 SUPERFAMILY SSF52777 1351 1618 6.78E-66 T 29-03-2018 CDC59_RS01415 daf839705750f114b38607bfc9e45cbe 2469 Gene3D G3DSA:3.40.50.980 540 701 8.4E-49 T 29-03-2018 CDC59_RS01415 daf839705750f114b38607bfc9e45cbe 2469 Gene3D G3DSA:3.40.50.980 1622 1780 2.8E-50 T 29-03-2018 CDC59_RS01415 daf839705750f114b38607bfc9e45cbe 2469 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1775 1786 - T 29-03-2018 IPR020845 AMP-binding, conserved site CDC59_RS01415 daf839705750f114b38607bfc9e45cbe 2469 SUPERFAMILY SSF47336 2133 2205 2.88E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS01415 daf839705750f114b38607bfc9e45cbe 2469 SUPERFAMILY SSF52777 1158 1345 7.11E-49 T 29-03-2018 CDC59_RS01415 daf839705750f114b38607bfc9e45cbe 2469 Gene3D G3DSA:3.30.300.30 956 1074 2.4E-43 T 29-03-2018 CDC59_RS01415 daf839705750f114b38607bfc9e45cbe 2469 Gene3D G3DSA:3.30.300.30 2027 2145 6.2E-42 T 29-03-2018 CDC59_RS01415 daf839705750f114b38607bfc9e45cbe 2469 Pfam PF00668 Condensation domain 139 525 6.8E-81 T 29-03-2018 IPR001242 Condensation domain CDC59_RS01415 daf839705750f114b38607bfc9e45cbe 2469 Pfam PF00668 Condensation domain 1157 1610 8.0E-102 T 29-03-2018 IPR001242 Condensation domain CDC59_RS01415 daf839705750f114b38607bfc9e45cbe 2469 Gene3D G3DSA:3.30.559.10 1139 1366 1.8E-50 T 29-03-2018 CDC59_RS01415 daf839705750f114b38607bfc9e45cbe 2469 Gene3D G3DSA:3.30.559.10 16 281 8.3E-27 T 29-03-2018 CDC59_RS01415 daf839705750f114b38607bfc9e45cbe 2469 Gene3D G3DSA:3.40.50.1820 2212 2469 2.2E-18 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS01415 daf839705750f114b38607bfc9e45cbe 2469 SUPERFAMILY SSF47336 1063 1134 7.98E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS01415 daf839705750f114b38607bfc9e45cbe 2469 Pfam PF00501 AMP-binding enzyme 1631 2032 2.5E-102 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CDC59_RS01415 daf839705750f114b38607bfc9e45cbe 2469 Pfam PF00501 AMP-binding enzyme 548 961 7.3E-105 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CDC59_RS01415 daf839705750f114b38607bfc9e45cbe 2469 Gene3D G3DSA:1.10.1200.10 2146 2211 1.1E-24 T 29-03-2018 CDC59_RS01415 daf839705750f114b38607bfc9e45cbe 2469 Gene3D G3DSA:1.10.1200.10 1461 1619 0.33 T 29-03-2018 CDC59_RS01415 daf839705750f114b38607bfc9e45cbe 2469 SUPERFAMILY SSF56801 503 1082 4.19E-167 T 29-03-2018 CDC59_RS01415 daf839705750f114b38607bfc9e45cbe 2469 SUPERFAMILY SSF52777 262 502 2.56E-64 T 29-03-2018 CDC59_RS01415 daf839705750f114b38607bfc9e45cbe 2469 Gene3D G3DSA:1.10.1200.10 1075 1138 1.4E-21 T 29-03-2018 CDC59_RS01415 daf839705750f114b38607bfc9e45cbe 2469 Gene3D G3DSA:3.40.50.980 1781 1939 9.7E-31 T 29-03-2018 CDC59_RS01415 daf839705750f114b38607bfc9e45cbe 2469 Gene3D G3DSA:3.40.50.980 702 864 9.7E-41 T 29-03-2018 CDC59_RS01415 daf839705750f114b38607bfc9e45cbe 2469 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2164 2179 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CDC59_RS01415 daf839705750f114b38607bfc9e45cbe 2469 Pfam PF00975 Thioesterase domain 2227 2453 1.8E-27 T 29-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CDC59_RS01415 daf839705750f114b38607bfc9e45cbe 2469 SMART SM00823 Phosphopantetheine attachment site 1071 1140 3.0E-6 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CDC59_RS01415 daf839705750f114b38607bfc9e45cbe 2469 SMART SM00823 Phosphopantetheine attachment site 2140 2209 3.4E-9 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CDC59_RS18555 e748ecce599cc53646673e2157184fc0 159 SUPERFAMILY SSF55724 9 145 1.15E-31 T 29-03-2018 IPR016123 Mog1/PsbP, alpha/beta/alpha sandwich Reactome: R-HSA-5576892 CDC59_RS18555 e748ecce599cc53646673e2157184fc0 159 Pfam PF08786 DcrB 12 141 2.1E-36 T 29-03-2018 IPR014894 Protein DcrB CDC59_RS18555 e748ecce599cc53646673e2157184fc0 159 Gene3D G3DSA:3.40.1000.10 3 149 6.8E-21 T 29-03-2018 CDC59_RS12855 f7ef8304804370f66c4ba8a03523c307 520 Gene3D G3DSA:1.10.3720.10 242 516 4.7E-29 T 29-03-2018 CDC59_RS12855 f7ef8304804370f66c4ba8a03523c307 520 SUPERFAMILY SSF161098 318 498 1.44E-35 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS12855 f7ef8304804370f66c4ba8a03523c307 520 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 342 500 2.0E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS12855 f7ef8304804370f66c4ba8a03523c307 520 SUPERFAMILY SSF53850 35 299 6.51E-53 T 29-03-2018 CDC59_RS12855 f7ef8304804370f66c4ba8a03523c307 520 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 35 296 9.6E-50 T 29-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 CDC59_RS12855 f7ef8304804370f66c4ba8a03523c307 520 Gene3D G3DSA:3.40.190.120 153 239 2.1E-27 T 29-03-2018 CDC59_RS12855 f7ef8304804370f66c4ba8a03523c307 520 Gene3D G3DSA:3.40.190.10 27 152 9.6E-12 T 29-03-2018 CDC59_RS12060 8d4ef9ba400fc772175c3a8c073aaa4b 215 TIGRFAM TIGR00547 lolA: outer membrane lipoprotein carrier protein LolA 10 213 1.1E-14 T 29-03-2018 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 CDC59_RS12060 8d4ef9ba400fc772175c3a8c073aaa4b 215 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 38 204 4.7E-38 T 29-03-2018 IPR004564 Outer membrane lipoprotein carrier protein LolA-like CDC59_RS12060 8d4ef9ba400fc772175c3a8c073aaa4b 215 Gene3D G3DSA:2.50.20.10 24 215 1.3E-41 T 29-03-2018 CDC59_RS12060 8d4ef9ba400fc772175c3a8c073aaa4b 215 SUPERFAMILY SSF89392 28 215 1.06E-44 T 29-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX CDC59_RS12060 8d4ef9ba400fc772175c3a8c073aaa4b 215 Hamap MF_00240 Outer-membrane lipoprotein carrier protein [lolA]. 13 215 30.057 T 29-03-2018 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 CDC59_RS19040 1dd10aacbdaa633d1ed24496fabcd3ac 205 Gene3D G3DSA:1.10.10.60 12 64 2.4E-16 T 29-03-2018 CDC59_RS19040 1dd10aacbdaa633d1ed24496fabcd3ac 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 61 4.9E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDC59_RS19040 1dd10aacbdaa633d1ed24496fabcd3ac 205 SUPERFAMILY SSF48498 88 199 1.06E-10 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CDC59_RS19040 1dd10aacbdaa633d1ed24496fabcd3ac 205 Gene3D G3DSA:1.10.357.10 65 202 4.0E-16 T 29-03-2018 CDC59_RS19040 1dd10aacbdaa633d1ed24496fabcd3ac 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 1.4E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDC59_RS19040 1dd10aacbdaa633d1ed24496fabcd3ac 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 1.4E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDC59_RS19040 1dd10aacbdaa633d1ed24496fabcd3ac 205 SUPERFAMILY SSF46689 11 78 2.87E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS03735 a610ab922b411542942191a83f1ffc20 362 Pfam PF02547 Queuosine biosynthesis protein 10 346 2.4E-132 T 29-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CDC59_RS03735 a610ab922b411542942191a83f1ffc20 362 Gene3D G3DSA:3.40.1780.10 180 347 2.4E-68 T 29-03-2018 CDC59_RS03735 a610ab922b411542942191a83f1ffc20 362 Gene3D G3DSA:3.40.1780.10 2 118 4.4E-29 T 29-03-2018 CDC59_RS03735 a610ab922b411542942191a83f1ffc20 362 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 8 347 46.833 T 29-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CDC59_RS03735 a610ab922b411542942191a83f1ffc20 362 SUPERFAMILY SSF111337 9 346 1.31E-133 T 29-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CDC59_RS03735 a610ab922b411542942191a83f1ffc20 362 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 9 346 8.2E-129 T 29-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CDC59_RS04500 15ef4f047a1098fc329ca8e7784eced4 368 Pfam PF00953 Glycosyl transferase family 4 77 234 1.0E-31 T 29-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CDC59_RS12435 0ac4853389bbfd63e6ab5c7c6c332905 134 SUPERFAMILY SSF55331 2 126 9.06E-35 T 29-03-2018 IPR014347 Tautomerase/MIF superfamily CDC59_RS12435 0ac4853389bbfd63e6ab5c7c6c332905 134 Pfam PF02962 5-carboxymethyl-2-hydroxymuconate isomerase 2 126 4.2E-30 T 29-03-2018 IPR004220 5-carboxymethyl-2-hydroxymuconate isomerase GO:0008704|GO:0019439 KEGG: 00350+5.3.3.10 CDC59_RS12435 0ac4853389bbfd63e6ab5c7c6c332905 134 Gene3D G3DSA:3.30.429.10 1 127 3.5E-35 T 29-03-2018 CDC59_RS16840 a44dfcf9c858217b5689ebc4c39f7431 412 Pfam PF07690 Major Facilitator Superfamily 15 360 4.0E-23 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDC59_RS16840 a44dfcf9c858217b5689ebc4c39f7431 412 Gene3D G3DSA:1.20.1250.20 7 193 1.8E-11 T 29-03-2018 CDC59_RS16840 a44dfcf9c858217b5689ebc4c39f7431 412 Gene3D G3DSA:1.20.1250.20 211 410 4.0E-19 T 29-03-2018 CDC59_RS16840 a44dfcf9c858217b5689ebc4c39f7431 412 SUPERFAMILY SSF103473 5 395 1.31E-39 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS10705 89131760b6036c9e161f42e54ec37216 183 SUPERFAMILY SSF54364 17 89 1.16E-28 T 29-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CDC59_RS10705 89131760b6036c9e161f42e54ec37216 183 Gene3D G3DSA:3.10.20.80 14 90 4.1E-31 T 29-03-2018 CDC59_RS10705 89131760b6036c9e161f42e54ec37216 183 SUPERFAMILY SSF55200 94 182 3.27E-33 T 29-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 CDC59_RS10705 89131760b6036c9e161f42e54ec37216 183 Gene3D G3DSA:3.30.110.10 91 183 3.5E-35 T 29-03-2018 CDC59_RS10705 89131760b6036c9e161f42e54ec37216 183 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 19 88 6.7E-31 T 29-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CDC59_RS10705 89131760b6036c9e161f42e54ec37216 183 ProSitePatterns PS00938 Initiation factor 3 signature. 70 83 - T 29-03-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 CDC59_RS10705 89131760b6036c9e161f42e54ec37216 183 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 95 180 1.8E-37 T 29-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 CDC59_RS10705 89131760b6036c9e161f42e54ec37216 183 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 13 182 30.45 T 29-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CDC59_RS10705 89131760b6036c9e161f42e54ec37216 183 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 19 182 4.8E-68 T 29-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CDC59_RS13750 51e03e3f7f5397ff959a8e082b76a909 226 SUPERFAMILY SSF53254 15 217 4.19E-65 T 29-03-2018 IPR029033 Histidine phosphatase superfamily CDC59_RS13750 51e03e3f7f5397ff959a8e082b76a909 226 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 19 28 - T 29-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 CDC59_RS13750 51e03e3f7f5397ff959a8e082b76a909 226 SMART SM00855 16 170 7.1E-26 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CDC59_RS13750 51e03e3f7f5397ff959a8e082b76a909 226 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 17 209 1.1E-68 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CDC59_RS13750 51e03e3f7f5397ff959a8e082b76a909 226 Gene3D G3DSA:3.40.50.1240 14 216 1.6E-61 T 29-03-2018 IPR029033 Histidine phosphatase superfamily CDC59_RS13750 51e03e3f7f5397ff959a8e082b76a909 226 PIRSF PIRSF000709 13 181 9.4E-13 T 29-03-2018 CDC59_RS19525 6cff4b19413e370121dc6bb4424b3339 414 SUPERFAMILY SSF46626 145 220 1.53E-30 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS19525 6cff4b19413e370121dc6bb4424b3339 414 SUPERFAMILY SSF46626 269 367 1.53E-30 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS19525 6cff4b19413e370121dc6bb4424b3339 414 Pfam PF03150 Di-haem cytochrome c peroxidase 2 171 5.4E-37 T 29-03-2018 IPR004852 Di-haem cytochrome c peroxidase GO:0016491|GO:0055114 CDC59_RS19525 6cff4b19413e370121dc6bb4424b3339 414 SUPERFAMILY SSF46626 2 152 1.48E-28 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS19525 6cff4b19413e370121dc6bb4424b3339 414 Gene3D G3DSA:1.10.760.10 174 410 2.3E-21 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS19525 6cff4b19413e370121dc6bb4424b3339 414 Gene3D G3DSA:1.10.760.10 1 173 2.1E-30 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS04345 b4512652f9743082f12315586c0965a5 284 TIGRFAM TIGR03177 pilus_cpaB: Flp pilus assembly protein CpaB 8 260 2.7E-80 T 29-03-2018 IPR017592 Pilus assembly, Flp-type CpaB CDC59_RS04345 b4512652f9743082f12315586c0965a5 284 Pfam PF08666 SAF domain 38 98 6.4E-10 T 29-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 CDC59_RS04345 b4512652f9743082f12315586c0965a5 284 Gene3D G3DSA:3.90.1210.10 36 100 1.5E-19 T 29-03-2018 CDC59_RS04345 b4512652f9743082f12315586c0965a5 284 SMART SM00858 37 99 1.2E-12 T 29-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 CDC59_RS04345 b4512652f9743082f12315586c0965a5 284 Pfam PF16976 Flp pilus assembly protein RcpC/CpaB 105 219 2.8E-29 T 29-03-2018 IPR031571 Flp pilus assembly protein RcpC/CpaB domain CDC59_RS02585 7252fd7232cd5f98cee7d4cc8657ae13 196 SUPERFAMILY SSF54211 89 179 5.82E-34 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CDC59_RS02585 7252fd7232cd5f98cee7d4cc8657ae13 196 Gene3D G3DSA:3.30.230.40 91 196 5.3E-32 T 29-03-2018 CDC59_RS02585 7252fd7232cd5f98cee7d4cc8657ae13 196 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 32 175 6.2E-63 T 29-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CDC59_RS02585 7252fd7232cd5f98cee7d4cc8657ae13 196 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 62 75 - T 29-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CDC59_RS02585 7252fd7232cd5f98cee7d4cc8657ae13 196 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 3 196 43.121 T 29-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CDC59_RS02585 7252fd7232cd5f98cee7d4cc8657ae13 196 Gene3D G3DSA:3.30.230.40 1 89 4.4E-36 T 29-03-2018 CDC59_RS02585 7252fd7232cd5f98cee7d4cc8657ae13 196 SUPERFAMILY SSF54211 3 87 1.52E-33 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CDC59_RS02585 7252fd7232cd5f98cee7d4cc8657ae13 196 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 157 169 - T 29-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CDC59_RS20995 ffbe1dfb875e08cefc7597e2c4f7793a 541 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 231 268 0.11 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CDC59_RS20995 ffbe1dfb875e08cefc7597e2c4f7793a 541 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 509 531 0.0075 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CDC59_RS20995 ffbe1dfb875e08cefc7597e2c4f7793a 541 Gene3D G3DSA:3.40.50.300 268 537 3.4E-60 T 29-03-2018 CDC59_RS20995 ffbe1dfb875e08cefc7597e2c4f7793a 541 Gene3D G3DSA:3.40.50.300 1 267 7.5E-62 T 29-03-2018 CDC59_RS20995 ffbe1dfb875e08cefc7597e2c4f7793a 541 SMART SM00382 304 496 6.4E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS20995 ffbe1dfb875e08cefc7597e2c4f7793a 541 SMART SM00382 29 228 4.2E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS20995 ffbe1dfb875e08cefc7597e2c4f7793a 541 SUPERFAMILY SSF52540 288 517 1.84E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS20995 ffbe1dfb875e08cefc7597e2c4f7793a 541 ProSitePatterns PS00211 ABC transporters family signature. 419 433 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS20995 ffbe1dfb875e08cefc7597e2c4f7793a 541 Pfam PF00005 ABC transporter 295 447 7.2E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS20995 ffbe1dfb875e08cefc7597e2c4f7793a 541 Pfam PF00005 ABC transporter 21 178 1.2E-22 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS20995 ffbe1dfb875e08cefc7597e2c4f7793a 541 SUPERFAMILY SSF52540 6 250 1.23E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS06330 73ffaa9bf769f37b70a238f3b8dcf89c 355 Gene3D G3DSA:3.20.20.70 12 214 1.6E-14 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS06330 73ffaa9bf769f37b70a238f3b8dcf89c 355 SUPERFAMILY SSF102114 14 266 2.75E-22 T 29-03-2018 CDC59_RS06330 73ffaa9bf769f37b70a238f3b8dcf89c 355 Pfam PF04055 Radical SAM superfamily 21 133 3.3E-8 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CDC59_RS05775 97a5cd9cc9bf2ec36cf8970b61750953 381 SUPERFAMILY SSF51556 83 379 2.85E-67 T 29-03-2018 IPR032466 Metal-dependent hydrolase CDC59_RS05775 97a5cd9cc9bf2ec36cf8970b61750953 381 SUPERFAMILY SSF51556 5 35 2.85E-67 T 29-03-2018 IPR032466 Metal-dependent hydrolase CDC59_RS05775 97a5cd9cc9bf2ec36cf8970b61750953 381 Pfam PF04909 Amidohydrolase 82 378 2.2E-33 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CDC59_RS05775 97a5cd9cc9bf2ec36cf8970b61750953 381 Gene3D G3DSA:3.20.20.140 2 381 2.6E-61 T 29-03-2018 CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 Pfam PF13018 Extended Signal Peptide of Type V secretion system 1 23 1.9E-7 T 29-03-2018 IPR024973 ESPR domain CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 Gene3D G3DSA:2.160.20.10 924 1009 0.11 T 29-03-2018 IPR012334 Pectin lyase fold CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 Gene3D G3DSA:2.160.20.10 1168 1329 4.3E-8 T 29-03-2018 IPR012334 Pectin lyase fold CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 Gene3D G3DSA:2.160.20.10 1010 1167 1.9E-6 T 29-03-2018 IPR012334 Pectin lyase fold CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 Gene3D G3DSA:2.160.20.10 364 453 0.018 T 29-03-2018 IPR012334 Pectin lyase fold CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 Gene3D G3DSA:2.160.20.10 617 775 9.5E-5 T 29-03-2018 IPR012334 Pectin lyase fold CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 Gene3D G3DSA:2.160.20.10 776 923 3.1E-9 T 29-03-2018 IPR012334 Pectin lyase fold CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 Gene3D G3DSA:2.160.20.10 454 570 0.015 T 29-03-2018 IPR012334 Pectin lyase fold CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 Gene3D G3DSA:2.160.20.10 73 363 5.0E-69 T 29-03-2018 IPR012334 Pectin lyase fold CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 Gene3D G3DSA:2.160.20.10 1587 1911 4.9E-10 T 29-03-2018 IPR012334 Pectin lyase fold CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 SUPERFAMILY SSF51126 78 344 6.91E-68 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 TIGRFAM TIGR01901 adhes_NPXG: filamentous hemagglutinin family N-terminal domain 105 201 4.9E-22 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 SMART SM00912 86 206 4.5E-51 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 Pfam PF13332 Haemagluttinin repeat 2101 2169 4.5E-6 T 29-03-2018 IPR025157 Hemagglutinin repeat CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 Pfam PF13332 Haemagluttinin repeat 2017 2088 5.4E-4 T 29-03-2018 IPR025157 Hemagglutinin repeat CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 Pfam PF13332 Haemagluttinin repeat 2179 2285 0.0043 T 29-03-2018 IPR025157 Hemagglutinin repeat CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 Pfam PF13332 Haemagluttinin repeat 2323 2495 1.1E-46 T 29-03-2018 IPR025157 Hemagglutinin repeat CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 Pfam PF05594 Haemagluttinin repeat 1243 1295 0.024 T 29-03-2018 IPR008619 Filamentous haemagglutinin repeat CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 Pfam PF05594 Haemagluttinin repeat 1178 1220 0.87 T 29-03-2018 IPR008619 Filamentous haemagglutinin repeat CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 Pfam PF05594 Haemagluttinin repeat 1524 1575 4.4 T 29-03-2018 IPR008619 Filamentous haemagglutinin repeat CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 Pfam PF05594 Haemagluttinin repeat 1296 1335 0.038 T 29-03-2018 IPR008619 Filamentous haemagglutinin repeat CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 Pfam PF05594 Haemagluttinin repeat 1850 1913 3.3 T 29-03-2018 IPR008619 Filamentous haemagglutinin repeat CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 Pfam PF05594 Haemagluttinin repeat 828 887 9.6E-4 T 29-03-2018 IPR008619 Filamentous haemagglutinin repeat CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 Pfam PF05594 Haemagluttinin repeat 620 690 84.0 T 29-03-2018 IPR008619 Filamentous haemagglutinin repeat CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 Pfam PF05594 Haemagluttinin repeat 1005 1049 0.054 T 29-03-2018 IPR008619 Filamentous haemagglutinin repeat CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 Pfam PF05594 Haemagluttinin repeat 1104 1170 8.7 T 29-03-2018 IPR008619 Filamentous haemagglutinin repeat CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 Pfam PF05594 Haemagluttinin repeat 1402 1462 120.0 T 29-03-2018 IPR008619 Filamentous haemagglutinin repeat CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 Pfam PF05594 Haemagluttinin repeat 922 972 20.0 T 29-03-2018 IPR008619 Filamentous haemagglutinin repeat CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 Pfam PF05594 Haemagluttinin repeat 450 530 4.7 T 29-03-2018 IPR008619 Filamentous haemagglutinin repeat CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 Pfam PF05594 Haemagluttinin repeat 253 330 7.7E-5 T 29-03-2018 IPR008619 Filamentous haemagglutinin repeat CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 Pfam PF05860 haemagglutination activity domain 73 204 8.2E-35 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 846 888 2.5E-5 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 620 655 0.02 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 974 1008 0.04 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 954 992 0.57 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1015 1050 1.1E-4 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 995 1032 0.0045 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1876 1913 0.11 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1228 1251 0.95 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1298 1335 1.2E-4 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 679 717 1.8E-4 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 768 798 0.073 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1102 1136 2.6E-4 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1173 1206 0.0015 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 925 950 0.025 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1856 1893 0.43 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 515 551 0.026 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 725 760 1.3 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 558 589 0.68 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 539 563 0.79 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1137 1163 0.0028 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 574 612 8.7E-4 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 314 350 1.4 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 784 822 0.01 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1061 1100 3.5E-10 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 829 865 5.3E-4 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 890 930 1.4E-5 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1255 1294 0.0082 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 597 635 0.0034 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1188 1220 4.2E-5 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS21390 195c27162275679c35faffaf7b83ef71 3327 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1525 1563 8.6E-7 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS04025 78b9420c20a9b92b4a3e2a041a3e5da5 569 SUPERFAMILY SSF52540 1 216 1.15E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS04025 78b9420c20a9b92b4a3e2a041a3e5da5 569 Gene3D G3DSA:3.40.50.300 197 520 2.6E-20 T 29-03-2018 CDC59_RS04025 78b9420c20a9b92b4a3e2a041a3e5da5 569 Gene3D G3DSA:3.40.50.300 1 196 3.3E-21 T 29-03-2018 CDC59_RS04025 78b9420c20a9b92b4a3e2a041a3e5da5 569 PIRSF PIRSF003128 1 553 2.2E-156 T 29-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 CDC59_RS04025 78b9420c20a9b92b4a3e2a041a3e5da5 569 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 548 7.9E-152 T 29-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 CDC59_RS04025 78b9420c20a9b92b4a3e2a041a3e5da5 569 SUPERFAMILY SSF52540 287 503 5.26E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS04025 78b9420c20a9b92b4a3e2a041a3e5da5 569 SUPERFAMILY SSF52540 3 50 5.26E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS04025 78b9420c20a9b92b4a3e2a041a3e5da5 569 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 505 1.0E-19 T 29-03-2018 IPR003395 RecF/RecN/SMC, N-terminal CDC59_RS06645 4dae5b8e2787ac6637ff6854ce51f583 510 PIRSF PIRSF036557 3 499 8.1E-236 T 29-03-2018 IPR012175 Xanthine dehydrogenase, small subunit, bacteria CDC59_RS06645 4dae5b8e2787ac6637ff6854ce51f583 510 Gene3D G3DSA:3.30.465.10 258 372 6.5E-30 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CDC59_RS06645 4dae5b8e2787ac6637ff6854ce51f583 510 SUPERFAMILY SSF54292 5 90 5.76E-17 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CDC59_RS06645 4dae5b8e2787ac6637ff6854ce51f583 510 Gene3D G3DSA:3.30.390.50 377 495 1.6E-30 T 29-03-2018 CDC59_RS06645 4dae5b8e2787ac6637ff6854ce51f583 510 Gene3D G3DSA:3.10.20.30 3 86 2.0E-26 T 29-03-2018 IPR012675 Beta-grasp domain CDC59_RS06645 4dae5b8e2787ac6637ff6854ce51f583 510 SUPERFAMILY SSF55447 379 490 1.06E-35 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal CDC59_RS06645 4dae5b8e2787ac6637ff6854ce51f583 510 Gene3D G3DSA:1.10.150.120 87 199 4.1E-34 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CDC59_RS06645 4dae5b8e2787ac6637ff6854ce51f583 510 SUPERFAMILY SSF47741 98 204 2.09E-32 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CDC59_RS06645 4dae5b8e2787ac6637ff6854ce51f583 510 Pfam PF01799 [2Fe-2S] binding domain 86 164 5.5E-29 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CDC59_RS06645 4dae5b8e2787ac6637ff6854ce51f583 510 TIGRFAM TIGR02963 xanthine_xdhA: xanthine dehydrogenase, small subunit 6 486 3.9E-212 T 29-03-2018 IPR014307 Xanthine dehydrogenase, small subunit GO:0004854|GO:0004855|GO:0050660|GO:0055114 KEGG: 00230+1.17.1.4|MetaCyc: PWY-5497|MetaCyc: PWY-5695|MetaCyc: PWY-6538|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-6999|Reactome: R-HSA-74259|Reactome: R-HSA-8851680 CDC59_RS06645 4dae5b8e2787ac6637ff6854ce51f583 510 Gene3D G3DSA:3.30.43.10 203 257 7.4E-13 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CDC59_RS06645 4dae5b8e2787ac6637ff6854ce51f583 510 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 43 51 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CDC59_RS06645 4dae5b8e2787ac6637ff6854ce51f583 510 SMART SM01092 381 486 1.7E-33 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal CDC59_RS06645 4dae5b8e2787ac6637ff6854ce51f583 510 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 13 72 1.2E-4 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CDC59_RS06645 4dae5b8e2787ac6637ff6854ce51f583 510 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 381 485 4.4E-32 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal CDC59_RS06645 4dae5b8e2787ac6637ff6854ce51f583 510 SUPERFAMILY SSF56176 206 370 1.49E-50 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CDC59_RS06645 4dae5b8e2787ac6637ff6854ce51f583 510 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 207 371 3.5E-48 T 29-03-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 CDC59_RS19050 eff5d5f9455ae3d96a2920e3f4171aee 547 Gene3D G3DSA:3.40.250.10 376 479 3.1E-16 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS19050 eff5d5f9455ae3d96a2920e3f4171aee 547 SUPERFAMILY SSF52821 259 362 4.19E-22 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS19050 eff5d5f9455ae3d96a2920e3f4171aee 547 SUPERFAMILY SSF52821 1 122 1.7E-26 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS19050 eff5d5f9455ae3d96a2920e3f4171aee 547 SUPERFAMILY SSF52821 375 523 1.31E-25 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS19050 eff5d5f9455ae3d96a2920e3f4171aee 547 Gene3D G3DSA:3.40.250.10 118 250 3.7E-21 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS19050 eff5d5f9455ae3d96a2920e3f4171aee 547 Gene3D G3DSA:3.40.250.10 251 375 5.1E-19 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS19050 eff5d5f9455ae3d96a2920e3f4171aee 547 SMART SM00450 268 364 7.7E-10 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS19050 eff5d5f9455ae3d96a2920e3f4171aee 547 SMART SM00450 378 472 3.5E-8 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS19050 eff5d5f9455ae3d96a2920e3f4171aee 547 SMART SM00450 131 229 4.1E-11 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS19050 eff5d5f9455ae3d96a2920e3f4171aee 547 SMART SM00450 7 105 2.1E-12 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS19050 eff5d5f9455ae3d96a2920e3f4171aee 547 Gene3D G3DSA:3.40.250.10 1 117 6.1E-20 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS19050 eff5d5f9455ae3d96a2920e3f4171aee 547 SUPERFAMILY SSF52821 108 236 1.03E-31 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS19050 eff5d5f9455ae3d96a2920e3f4171aee 547 Pfam PF00581 Rhodanese-like domain 275 358 1.2E-8 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS19050 eff5d5f9455ae3d96a2920e3f4171aee 547 Pfam PF00581 Rhodanese-like domain 11 102 4.0E-8 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS19050 eff5d5f9455ae3d96a2920e3f4171aee 547 Pfam PF00581 Rhodanese-like domain 133 225 5.2E-12 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS19050 eff5d5f9455ae3d96a2920e3f4171aee 547 Pfam PF00581 Rhodanese-like domain 381 468 3.1E-6 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS14590 57df7953ac5d524686a7a0f621ffefc6 496 SUPERFAMILY SSF48056 35 313 3.27E-56 T 29-03-2018 IPR008922 Uncharacterised domain, di-copper centre Reactome: R-HSA-5662702 CDC59_RS14590 57df7953ac5d524686a7a0f621ffefc6 496 Gene3D G3DSA:1.10.1280.10 25 316 2.7E-55 T 29-03-2018 IPR008922 Uncharacterised domain, di-copper centre Reactome: R-HSA-5662702 CDC59_RS14590 57df7953ac5d524686a7a0f621ffefc6 496 Pfam PF12143 Protein of unknown function (DUF_B2219) 361 481 4.0E-23 T 29-03-2018 IPR022740 Polyphenol oxidase, C-terminal GO:0004097|GO:0055114 KEGG: 00350+1.10.3.1|KEGG: 00950+1.10.3.1|MetaCyc: PWY-6752 CDC59_RS14590 57df7953ac5d524686a7a0f621ffefc6 496 PRINTS PR00092 Tyrosinase copper-binding domain signature 226 237 2.5E-14 T 29-03-2018 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 Reactome: R-HSA-5662702 CDC59_RS14590 57df7953ac5d524686a7a0f621ffefc6 496 PRINTS PR00092 Tyrosinase copper-binding domain signature 245 263 2.5E-14 T 29-03-2018 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 Reactome: R-HSA-5662702 CDC59_RS14590 57df7953ac5d524686a7a0f621ffefc6 496 PRINTS PR00092 Tyrosinase copper-binding domain signature 93 110 2.5E-14 T 29-03-2018 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 Reactome: R-HSA-5662702 CDC59_RS14590 57df7953ac5d524686a7a0f621ffefc6 496 PRINTS PR00092 Tyrosinase copper-binding domain signature 124 129 2.5E-14 T 29-03-2018 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 Reactome: R-HSA-5662702 CDC59_RS14590 57df7953ac5d524686a7a0f621ffefc6 496 ProSitePatterns PS00497 Tyrosinase CuA-binding region signature. 93 110 - T 29-03-2018 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 Reactome: R-HSA-5662702 CDC59_RS14590 57df7953ac5d524686a7a0f621ffefc6 496 Pfam PF12142 Polyphenol oxidase middle domain 270 320 4.7E-13 T 29-03-2018 IPR022739 Polyphenol oxidase, central domain GO:0004097|GO:0055114 KEGG: 00350+1.10.3.1|KEGG: 00950+1.10.3.1|MetaCyc: PWY-6752 CDC59_RS14590 57df7953ac5d524686a7a0f621ffefc6 496 Pfam PF00264 Common central domain of tyrosinase 72 265 1.4E-35 T 29-03-2018 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 Reactome: R-HSA-5662702 CDC59_RS14590 57df7953ac5d524686a7a0f621ffefc6 496 ProSitePatterns PS00498 Tyrosinase and hemocyanins CuB-binding region signature. 246 257 - T 29-03-2018 IPR002227 Tyrosinase copper-binding domain GO:0008152|GO:0016491 Reactome: R-HSA-5662702 CDC59_RS00495 0ce5dfcd438da3e9a8224375537c117e 196 Gene3D G3DSA:3.40.50.850 2 195 9.5E-40 T 29-03-2018 CDC59_RS00495 0ce5dfcd438da3e9a8224375537c117e 196 Pfam PF00857 Isochorismatase family 13 187 8.6E-36 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CDC59_RS00495 0ce5dfcd438da3e9a8224375537c117e 196 SUPERFAMILY SSF52499 8 194 2.88E-45 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CDC59_RS16435 22d59f36363c695a66a302814a39e358 1060 SMART SM00490 616 706 2.7E-7 T 29-03-2018 IPR001650 Helicase, C-terminal CDC59_RS16435 22d59f36363c695a66a302814a39e358 1060 Pfam PF00271 Helicase conserved C-terminal domain 622 706 3.5E-5 T 29-03-2018 IPR001650 Helicase, C-terminal CDC59_RS16435 22d59f36363c695a66a302814a39e358 1060 SUPERFAMILY SSF52540 279 427 1.0E-27 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS16435 22d59f36363c695a66a302814a39e358 1060 SUPERFAMILY SSF52540 527 583 1.0E-27 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS16435 22d59f36363c695a66a302814a39e358 1060 SUPERFAMILY SSF52540 623 716 1.0E-27 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS16435 22d59f36363c695a66a302814a39e358 1060 SMART SM00487 252 455 3.3E-6 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CDC59_RS16435 22d59f36363c695a66a302814a39e358 1060 Pfam PF00270 DEAD/DEAH box helicase 278 425 6.2E-12 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CDC59_RS16435 22d59f36363c695a66a302814a39e358 1060 Gene3D G3DSA:3.40.50.300 248 450 2.5E-17 T 29-03-2018 CDC59_RS16435 22d59f36363c695a66a302814a39e358 1060 Gene3D G3DSA:3.40.50.300 539 767 6.8E-15 T 29-03-2018 CDC59_RS20555 5ad72de59b5f7f3287b17895d68dc819 625 Pfam PF02517 CAAX protease self-immunity 532 617 1.5E-16 T 29-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CDC59_RS18905 4a6aa86bd98dbac506d68bfa86345e6c 128 SUPERFAMILY SSF54523 12 128 2.04E-22 T 29-03-2018 CDC59_RS18905 4a6aa86bd98dbac506d68bfa86345e6c 128 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 9 32 1.1E-9 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS18905 4a6aa86bd98dbac506d68bfa86345e6c 128 PRINTS PR00813 Bacterial general secretion pathway protein G signature 11 36 2.4E-8 T 29-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 CDC59_RS18905 4a6aa86bd98dbac506d68bfa86345e6c 128 PRINTS PR00813 Bacterial general secretion pathway protein G signature 47 65 2.4E-8 T 29-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 CDC59_RS18905 4a6aa86bd98dbac506d68bfa86345e6c 128 Gene3D G3DSA:3.30.700.10 12 125 2.9E-16 T 29-03-2018 CDC59_RS18905 4a6aa86bd98dbac506d68bfa86345e6c 128 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 10 30 - T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS18905 4a6aa86bd98dbac506d68bfa86345e6c 128 Pfam PF07963 Prokaryotic N-terminal methylation motif 8 32 7.3E-10 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS12570 6c96f330e1f5bf7043aa3220040604ff 77 Gene3D G3DSA:2.30.170.40 2 75 2.1E-30 T 29-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS12570 6c96f330e1f5bf7043aa3220040604ff 77 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 67 21.439 T 29-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS12570 6c96f330e1f5bf7043aa3220040604ff 77 Pfam PF00830 Ribosomal L28 family 3 62 7.2E-28 T 29-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS12570 6c96f330e1f5bf7043aa3220040604ff 77 SUPERFAMILY SSF143800 2 74 6.28E-31 T 29-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS12570 6c96f330e1f5bf7043aa3220040604ff 77 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 57 3.6E-28 T 29-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS06210 bd991a80e001de49a4a31191d63d4030 1176 Gene3D G3DSA:1.10.150.280 829 896 4.3E-8 T 29-03-2018 CDC59_RS06210 bd991a80e001de49a4a31191d63d4030 1176 Gene3D G3DSA:2.40.50.140 1001 1091 1.7E-9 T 29-03-2018 CDC59_RS06210 bd991a80e001de49a4a31191d63d4030 1176 SMART SM00481 7 74 7.0E-22 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CDC59_RS06210 bd991a80e001de49a4a31191d63d4030 1176 Pfam PF02811 PHP domain 8 180 3.0E-38 T 29-03-2018 IPR004013 PHP domain GO:0003824 CDC59_RS06210 bd991a80e001de49a4a31191d63d4030 1176 Gene3D G3DSA:3.20.20.140 5 265 1.2E-32 T 29-03-2018 CDC59_RS06210 bd991a80e001de49a4a31191d63d4030 1176 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 298 736 3.6E-175 T 29-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDC59_RS06210 bd991a80e001de49a4a31191d63d4030 1176 Pfam PF14579 Helix-hairpin-helix motif 811 900 3.9E-29 T 29-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDC59_RS06210 bd991a80e001de49a4a31191d63d4030 1176 SUPERFAMILY SSF89550 6 270 4.32E-10 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CDC59_RS06210 bd991a80e001de49a4a31191d63d4030 1176 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 6 980 0.0 T 29-03-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDC59_RS17190 a20cfe22be9d8c1cacd46550e7e87626 481 TIGRFAM TIGR03496 FliI_clade1: flagellar protein export ATPase FliI 45 478 5.7E-195 T 29-03-2018 IPR020005 Flagellar export ATPase FliI, clade 1 GO:0016887|GO:0044780|GO:0071973 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CDC59_RS17190 a20cfe22be9d8c1cacd46550e7e87626 481 Gene3D G3DSA:3.40.50.300 94 400 1.4E-80 T 29-03-2018 CDC59_RS17190 a20cfe22be9d8c1cacd46550e7e87626 481 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 29 480 9.1E-172 T 29-03-2018 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CDC59_RS17190 a20cfe22be9d8c1cacd46550e7e87626 481 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 391 400 - T 29-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CDC59_RS17190 a20cfe22be9d8c1cacd46550e7e87626 481 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 185 400 7.8E-73 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CDC59_RS17190 a20cfe22be9d8c1cacd46550e7e87626 481 SUPERFAMILY SSF52540 130 406 2.36E-92 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS17190 a20cfe22be9d8c1cacd46550e7e87626 481 SMART SM00382 197 384 2.8E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS17825 f0382fc49c597b91639d3dfc268ba7d5 777 Pfam PF00593 TonB dependent receptor 325 775 7.5E-58 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CDC59_RS17825 f0382fc49c597b91639d3dfc268ba7d5 777 Gene3D G3DSA:2.40.170.20 204 777 2.2E-66 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CDC59_RS17825 f0382fc49c597b91639d3dfc268ba7d5 777 Gene3D G3DSA:2.170.130.10 60 203 1.1E-32 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CDC59_RS17825 f0382fc49c597b91639d3dfc268ba7d5 777 SUPERFAMILY SSF56935 65 777 3.97E-109 T 29-03-2018 CDC59_RS17825 f0382fc49c597b91639d3dfc268ba7d5 777 TIGRFAM TIGR01786 TonB-hemlactrns: TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein 71 777 2.0E-115 T 29-03-2018 IPR010949 TonB-dependent haemoglobin/transferrin/lactoferrin receptor GO:0004872|GO:0005215|GO:0006810|GO:0019867 CDC59_RS17825 f0382fc49c597b91639d3dfc268ba7d5 777 TIGRFAM TIGR01785 TonB-hemin: TonB-dependent heme/hemoglobin receptor family protein 69 777 1.0E-112 T 29-03-2018 IPR011276 TonB-dependent haem/haemoglobin receptor GO:0004872|GO:0005215|GO:0006810|GO:0019867 CDC59_RS17825 f0382fc49c597b91639d3dfc268ba7d5 777 Pfam PF07715 TonB-dependent Receptor Plug Domain 84 206 2.8E-25 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CDC59_RS02255 82be8e78c3612b3bca23643f144fe1d8 91 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.625 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS02255 82be8e78c3612b3bca23643f144fe1d8 91 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 91 6.7E-46 T 29-03-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 CDC59_RS02255 82be8e78c3612b3bca23643f144fe1d8 91 Gene3D G3DSA:3.30.860.10 1 91 5.3E-41 T 29-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS02255 82be8e78c3612b3bca23643f144fe1d8 91 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 3.1E-24 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS02255 82be8e78c3612b3bca23643f144fe1d8 91 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 3.1E-24 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS02255 82be8e78c3612b3bca23643f144fe1d8 91 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 3.1E-24 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS02255 82be8e78c3612b3bca23643f144fe1d8 91 Pfam PF00203 Ribosomal protein S19 3 83 5.6E-37 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS02255 82be8e78c3612b3bca23643f144fe1d8 91 PIRSF PIRSF002144 1 91 4.5E-33 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS02255 82be8e78c3612b3bca23643f144fe1d8 91 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 29-03-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS02255 82be8e78c3612b3bca23643f144fe1d8 91 SUPERFAMILY SSF54570 3 84 2.09E-35 T 29-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS13405 5eecfb63d654ff0dec23dc775bb9f217 158 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 4 152 3.9E-60 T 29-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 CDC59_RS13405 5eecfb63d654ff0dec23dc775bb9f217 158 SUPERFAMILY SSF55040 11 155 1.12E-61 T 29-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CDC59_RS13405 5eecfb63d654ff0dec23dc775bb9f217 158 Pfam PF01967 MoaC family 15 150 1.4E-54 T 29-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CDC59_RS13405 5eecfb63d654ff0dec23dc775bb9f217 158 Gene3D G3DSA:3.30.70.640 2 158 2.9E-70 T 29-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CDC59_RS13405 5eecfb63d654ff0dec23dc775bb9f217 158 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase accessory protein [moaC]. 2 158 36.818 T 29-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 CDC59_RS21220 2e8d4d7bae487e54be289a9eae0b1aa0 445 Gene3D G3DSA:3.90.1150.10 333 444 1.1E-17 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS21220 2e8d4d7bae487e54be289a9eae0b1aa0 445 Pfam PF00202 Aminotransferase class-III 23 440 1.8E-87 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CDC59_RS21220 2e8d4d7bae487e54be289a9eae0b1aa0 445 PIRSF PIRSF000521 26 444 1.1E-23 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CDC59_RS21220 2e8d4d7bae487e54be289a9eae0b1aa0 445 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 254 291 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CDC59_RS21220 2e8d4d7bae487e54be289a9eae0b1aa0 445 SUPERFAMILY SSF53383 6 444 2.89E-120 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS21220 2e8d4d7bae487e54be289a9eae0b1aa0 445 Gene3D G3DSA:3.40.640.10 202 332 9.3E-45 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDC59_RS21220 2e8d4d7bae487e54be289a9eae0b1aa0 445 Gene3D G3DSA:3.90.1150.10 5 201 2.4E-44 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS08405 d7054fca3de29dbaf1369c3f63dad6f8 471 ProSitePatterns PS00180 Glutamine synthetase signature 1. 52 70 - T 29-03-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CDC59_RS08405 d7054fca3de29dbaf1369c3f63dad6f8 471 Gene3D G3DSA:3.10.20.70 4 106 2.1E-29 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CDC59_RS08405 d7054fca3de29dbaf1369c3f63dad6f8 471 Gene3D G3DSA:3.30.590.10 107 460 6.5E-124 T 29-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CDC59_RS08405 d7054fca3de29dbaf1369c3f63dad6f8 471 SUPERFAMILY SSF54368 5 101 8.5E-37 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CDC59_RS08405 d7054fca3de29dbaf1369c3f63dad6f8 471 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 7 470 1.7E-205 T 29-03-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CDC59_RS08405 d7054fca3de29dbaf1369c3f63dad6f8 471 SUPERFAMILY SSF55931 104 470 5.0E-139 T 29-03-2018 CDC59_RS08405 d7054fca3de29dbaf1369c3f63dad6f8 471 SMART SM01230 104 381 2.5E-148 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CDC59_RS08405 d7054fca3de29dbaf1369c3f63dad6f8 471 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 97 8.4E-31 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CDC59_RS08405 d7054fca3de29dbaf1369c3f63dad6f8 471 Pfam PF00120 Glutamine synthetase, catalytic domain 105 468 9.7E-139 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CDC59_RS08405 d7054fca3de29dbaf1369c3f63dad6f8 471 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 261 276 - T 29-03-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CDC59_RS08405 d7054fca3de29dbaf1369c3f63dad6f8 471 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 388 400 - T 29-03-2018 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CDC59_RS18650 f292a8b77a587c7d333342c10bda81c9 224 SMART SM00448 1 111 3.9E-42 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS18650 f292a8b77a587c7d333342c10bda81c9 224 SUPERFAMILY SSF52172 1 176 1.04E-39 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS18650 f292a8b77a587c7d333342c10bda81c9 224 SMART SM00862 144 219 1.1E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDC59_RS18650 f292a8b77a587c7d333342c10bda81c9 224 Pfam PF00072 Response regulator receiver domain 4 112 3.2E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS18650 f292a8b77a587c7d333342c10bda81c9 224 Gene3D G3DSA:1.10.10.10 120 223 9.7E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS18650 f292a8b77a587c7d333342c10bda81c9 224 Gene3D G3DSA:3.40.50.2300 1 119 9.4E-33 T 29-03-2018 CDC59_RS18650 f292a8b77a587c7d333342c10bda81c9 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 144 219 2.3E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDC59_RS18650 f292a8b77a587c7d333342c10bda81c9 224 TIGRFAM TIGR01387 cztR_silR_copR: heavy metal response regulator 3 219 1.7E-106 T 29-03-2018 IPR006291 Transcriptional regulatory protein PcoR, heavy metal response GO:0003677|GO:0006355 CDC59_RS19355 b71d7a6784b3e2c8dda2032d548131c9 219 PIRSF PIRSF000190 1 219 7.1E-67 T 29-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CDC59_RS19355 b71d7a6784b3e2c8dda2032d548131c9 219 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 177 219 1.4E-15 T 29-03-2018 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CDC59_RS19355 b71d7a6784b3e2c8dda2032d548131c9 219 Gene3D G3DSA:2.30.110.10 15 219 9.7E-64 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CDC59_RS19355 b71d7a6784b3e2c8dda2032d548131c9 219 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 187 200 - T 29-03-2018 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CDC59_RS19355 b71d7a6784b3e2c8dda2032d548131c9 219 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 11 219 36.296 T 29-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CDC59_RS19355 b71d7a6784b3e2c8dda2032d548131c9 219 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 25 217 1.8E-63 T 29-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CDC59_RS19355 b71d7a6784b3e2c8dda2032d548131c9 219 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 41 124 2.7E-24 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CDC59_RS19355 b71d7a6784b3e2c8dda2032d548131c9 219 SUPERFAMILY SSF50475 28 219 1.76E-58 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CDC59_RS02945 92d6e37e0099081993854b985aaff18f 378 PIRSF PIRSF019422 8 377 4.3E-109 T 29-03-2018 IPR026044 Membrane-bound lytic murein transglycosylase A CDC59_RS02945 92d6e37e0099081993854b985aaff18f 378 Pfam PF03562 MltA specific insert domain 66 271 4.6E-63 T 29-03-2018 IPR005300 Lytic transglycosylase MltA, domain B GO:0004553 CDC59_RS02945 92d6e37e0099081993854b985aaff18f 378 SUPERFAMILY SSF50685 25 370 1.53E-117 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CDC59_RS02945 92d6e37e0099081993854b985aaff18f 378 Gene3D G3DSA:2.40.40.10 171 377 2.6E-49 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CDC59_RS02945 92d6e37e0099081993854b985aaff18f 378 SMART SM00925 140 272 7.3E-65 T 29-03-2018 IPR005300 Lytic transglycosylase MltA, domain B GO:0004553 CDC59_RS02945 92d6e37e0099081993854b985aaff18f 378 Pfam PF06725 3D domain 293 366 2.5E-25 T 29-03-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 CDC59_RS02945 92d6e37e0099081993854b985aaff18f 378 Gene3D G3DSA:2.40.40.10 49 170 7.4E-20 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CDC59_RS05505 fcc53d4df228695a385531c61ddd5262 425 Pfam PF13432 Tetratricopeptide repeat 49 90 0.0011 T 29-03-2018 CDC59_RS05505 fcc53d4df228695a385531c61ddd5262 425 Pfam PF14559 Tetratricopeptide repeat 191 246 1.2E-6 T 29-03-2018 CDC59_RS05505 fcc53d4df228695a385531c61ddd5262 425 Gene3D G3DSA:1.25.40.10 182 332 4.9E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS05505 fcc53d4df228695a385531c61ddd5262 425 Gene3D G3DSA:1.25.40.10 19 181 3.2E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS05505 fcc53d4df228695a385531c61ddd5262 425 SMART SM00028 214 247 110.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CDC59_RS05505 fcc53d4df228695a385531c61ddd5262 425 SMART SM00028 180 213 0.041 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CDC59_RS05505 fcc53d4df228695a385531c61ddd5262 425 SMART SM00028 36 69 50.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CDC59_RS05505 fcc53d4df228695a385531c61ddd5262 425 SUPERFAMILY SSF48452 183 248 7.96E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS05505 fcc53d4df228695a385531c61ddd5262 425 SUPERFAMILY SSF48452 43 109 7.96E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS05505 fcc53d4df228695a385531c61ddd5262 425 Hamap MF_00994 Lipopolysaccharide assembly protein B [lapB]. 6 416 34.179 T 29-03-2018 IPR030865 Lipopolysaccharide assembly protein B GO:0008653 CDC59_RS03640 9501c5b0820f0f3547015ce54fed527c 120 SUPERFAMILY SSF50692 1 117 1.74E-49 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain CDC59_RS03640 9501c5b0820f0f3547015ce54fed527c 120 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 117 6.4E-53 T 29-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CDC59_RS03640 9501c5b0820f0f3547015ce54fed527c 120 Gene3D G3DSA:2.40.40.20 1 117 1.6E-52 T 29-03-2018 CDC59_RS03640 9501c5b0820f0f3547015ce54fed527c 120 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 93 5.0E-47 T 29-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CDC59_RS03640 9501c5b0820f0f3547015ce54fed527c 120 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 120 72.126 T 29-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CDC59_RS03640 9501c5b0820f0f3547015ce54fed527c 120 PIRSF PIRSF006246 1 120 2.1E-53 T 29-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CDC59_RS03640 9501c5b0820f0f3547015ce54fed527c 120 Pfam PF02261 Aspartate decarboxylase 1 114 8.1E-51 T 29-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CDC59_RS16285 9cb4d6d0ec693aa346217558dccb9830 143 SMART SM00960 17 105 3.3E-6 T 29-03-2018 IPR004942 Roadblock/LAMTOR2 domain CDC59_RS16285 9cb4d6d0ec693aa346217558dccb9830 143 SUPERFAMILY SSF103196 12 132 3.84E-18 T 29-03-2018 CDC59_RS16285 9cb4d6d0ec693aa346217558dccb9830 143 Gene3D G3DSA:3.30.450.30 13 136 4.5E-16 T 29-03-2018 CDC59_RS16285 9cb4d6d0ec693aa346217558dccb9830 143 Pfam PF03259 Roadblock/LC7 domain 28 103 1.6E-5 T 29-03-2018 IPR004942 Roadblock/LAMTOR2 domain CDC59_RS08240 2f6e3d67a76d9c6359d6fe47514ef7ac 250 Gene3D G3DSA:3.40.50.1220 64 250 1.2E-55 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CDC59_RS08240 2f6e3d67a76d9c6359d6fe47514ef7ac 250 Gene3D G3DSA:3.40.50.1220 3 63 5.6E-9 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CDC59_RS08240 2f6e3d67a76d9c6359d6fe47514ef7ac 250 Hamap MF_01121 NAD-dependent protein deacylase [cobB]. 25 249 59.088 T 29-03-2018 IPR027546 Sirtuin, class III GO:0036054|GO:0036055|GO:0070403 Reactome: R-HSA-2151201 CDC59_RS08240 2f6e3d67a76d9c6359d6fe47514ef7ac 250 SUPERFAMILY SSF52467 9 248 5.11E-80 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CDC59_RS08240 2f6e3d67a76d9c6359d6fe47514ef7ac 250 Pfam PF02146 Sir2 family 32 203 2.3E-45 T 29-03-2018 IPR003000 Sirtuin family GO:0070403 CDC59_RS13010 ad2e863677844d9520bcd7bcc2e1eaf0 161 SUPERFAMILY SSF89963 89 161 1.31E-27 T 29-03-2018 IPR007551 Protein of unknown function DUF520 CDC59_RS13010 ad2e863677844d9520bcd7bcc2e1eaf0 161 Pfam PF04461 Protein of unknown function (DUF520) 2 160 7.7E-66 T 29-03-2018 IPR007551 Protein of unknown function DUF520 CDC59_RS13010 ad2e863677844d9520bcd7bcc2e1eaf0 161 SUPERFAMILY SSF89963 2 87 1.44E-31 T 29-03-2018 IPR007551 Protein of unknown function DUF520 CDC59_RS13010 ad2e863677844d9520bcd7bcc2e1eaf0 161 Gene3D G3DSA:3.30.70.860 96 160 3.1E-31 T 29-03-2018 IPR035571 UPF0234/UPF0381 domain CDC59_RS13010 ad2e863677844d9520bcd7bcc2e1eaf0 161 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 1 161 28.784 T 29-03-2018 IPR007551 Protein of unknown function DUF520 CDC59_RS13010 ad2e863677844d9520bcd7bcc2e1eaf0 161 Gene3D G3DSA:3.30.70.990 10 95 1.8E-32 T 29-03-2018 IPR035570 UPF0234 N-terminal domain CDC59_RS12930 bbcfddbf719fda76c4614694f4ff33cf 349 Pfam PF02606 Tetraacyldisaccharide-1-P 4'-kinase 23 334 1.5E-103 T 29-03-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 CDC59_RS12930 bbcfddbf719fda76c4614694f4ff33cf 349 TIGRFAM TIGR00682 lpxK: tetraacyldisaccharide 4'-kinase 29 318 1.2E-64 T 29-03-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 CDC59_RS12930 bbcfddbf719fda76c4614694f4ff33cf 349 SUPERFAMILY SSF52540 56 173 9.49E-12 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS12930 bbcfddbf719fda76c4614694f4ff33cf 349 Gene3D G3DSA:3.40.50.300 56 180 4.6E-7 T 29-03-2018 CDC59_RS12930 bbcfddbf719fda76c4614694f4ff33cf 349 Hamap MF_00409 Tetraacyldisaccharide 4'-kinase [lpxK]. 11 336 38.729 T 29-03-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 CDC59_RS11240 7fd783b394ad538f0b1bae8967c7f81e 252 Pfam PF00196 Bacterial regulatory proteins, luxR family 182 237 4.8E-16 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS11240 7fd783b394ad538f0b1bae8967c7f81e 252 Gene3D G3DSA:1.10.10.10 164 241 4.9E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS11240 7fd783b394ad538f0b1bae8967c7f81e 252 Gene3D G3DSA:3.30.450.80 3 163 5.7E-5 T 29-03-2018 CDC59_RS11240 7fd783b394ad538f0b1bae8967c7f81e 252 SUPERFAMILY SSF46894 170 238 1.97E-18 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CDC59_RS11240 7fd783b394ad538f0b1bae8967c7f81e 252 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 197 213 3.0E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS11240 7fd783b394ad538f0b1bae8967c7f81e 252 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 197 3.0E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS11240 7fd783b394ad538f0b1bae8967c7f81e 252 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 213 225 3.0E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS11240 7fd783b394ad538f0b1bae8967c7f81e 252 SMART SM00421 180 237 3.2E-20 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS16195 c4cbbb073fac0378c6400d2bee2678bb 396 Gene3D G3DSA:2.40.110.10 128 223 5.2E-34 T 29-03-2018 CDC59_RS16195 c4cbbb073fac0378c6400d2bee2678bb 396 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 341 360 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CDC59_RS16195 c4cbbb073fac0378c6400d2bee2678bb 396 Gene3D G3DSA:1.10.540.10 2 127 4.2E-19 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CDC59_RS16195 c4cbbb073fac0378c6400d2bee2678bb 396 SUPERFAMILY SSF56645 11 245 2.23E-61 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CDC59_RS16195 c4cbbb073fac0378c6400d2bee2678bb 396 Gene3D G3DSA:1.20.140.10 224 394 2.8E-50 T 29-03-2018 CDC59_RS16195 c4cbbb073fac0378c6400d2bee2678bb 396 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 131 143 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CDC59_RS16195 c4cbbb073fac0378c6400d2bee2678bb 396 SUPERFAMILY SSF47203 234 385 6.44E-50 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CDC59_RS16195 c4cbbb073fac0378c6400d2bee2678bb 396 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 129 220 5.0E-23 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CDC59_RS16195 c4cbbb073fac0378c6400d2bee2678bb 396 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 14 125 4.7E-14 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CDC59_RS16195 c4cbbb073fac0378c6400d2bee2678bb 396 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 234 382 4.0E-46 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CDC59_RS13380 71e3eb529a15669a6c1f10c1325b64a8 341 TIGRFAM TIGR02195 heptsyl_trn_II: lipopolysaccharide heptosyltransferase II 4 338 3.4E-137 T 29-03-2018 IPR011910 ADP-heptose--LPS heptosyltransferase 2 GO:0009103|GO:0016757 CDC59_RS13380 71e3eb529a15669a6c1f10c1325b64a8 341 Gene3D G3DSA:3.40.50.2000 1 153 8.9E-35 T 29-03-2018 CDC59_RS13380 71e3eb529a15669a6c1f10c1325b64a8 341 Gene3D G3DSA:3.40.50.2000 158 340 1.6E-48 T 29-03-2018 CDC59_RS13380 71e3eb529a15669a6c1f10c1325b64a8 341 SUPERFAMILY SSF53756 3 339 4.24E-99 T 29-03-2018 CDC59_RS13380 71e3eb529a15669a6c1f10c1325b64a8 341 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 74 318 1.1E-66 T 29-03-2018 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 CDC59_RS22050 fff8f93e9bbf3f20c01133b986bcc7bd 441 SUPERFAMILY SSF103473 11 420 1.27E-55 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS22050 fff8f93e9bbf3f20c01133b986bcc7bd 441 Pfam PF07690 Major Facilitator Superfamily 25 384 2.3E-25 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDC59_RS22050 fff8f93e9bbf3f20c01133b986bcc7bd 441 Gene3D G3DSA:1.20.1250.20 2 224 8.2E-25 T 29-03-2018 CDC59_RS22050 fff8f93e9bbf3f20c01133b986bcc7bd 441 Gene3D G3DSA:1.20.1250.20 225 425 7.4E-17 T 29-03-2018 CDC59_RS10350 8c5271eac39b861404a874d194dd4828 277 TIGRFAM TIGR03302 OM_YfiO: outer membrane assembly lipoprotein YfiO 18 261 6.1E-91 T 29-03-2018 IPR017689 Outer membrane protein assembly factor BamD CDC59_RS10350 8c5271eac39b861404a874d194dd4828 277 Hamap MF_00922 Outer membrane protein assembly factor BamD [bamD]. 14 256 39.66 T 29-03-2018 IPR017689 Outer membrane protein assembly factor BamD CDC59_RS10350 8c5271eac39b861404a874d194dd4828 277 Pfam PF13525 Outer membrane lipoprotein 46 250 5.1E-67 T 29-03-2018 CDC59_RS10350 8c5271eac39b861404a874d194dd4828 277 SUPERFAMILY SSF48452 47 120 9.25E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS10350 8c5271eac39b861404a874d194dd4828 277 SUPERFAMILY SSF48452 193 241 9.25E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS10350 8c5271eac39b861404a874d194dd4828 277 Gene3D G3DSA:1.25.20.10 44 272 7.6E-23 T 29-03-2018 CDC59_RS01580 ffe1439a31447e5ed99533389fdb48b9 262 SUPERFAMILY SSF51735 1 257 5.88E-71 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS01580 ffe1439a31447e5ed99533389fdb48b9 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 257 6.8E-49 T 29-03-2018 CDC59_RS01580 ffe1439a31447e5ed99533389fdb48b9 262 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 187 0.004 T 29-03-2018 CDC59_RS01580 ffe1439a31447e5ed99533389fdb48b9 262 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CDC59_RS01580 ffe1439a31447e5ed99533389fdb48b9 262 Gene3D G3DSA:3.40.50.720 1 258 1.2E-65 T 29-03-2018 CDC59_RS01580 ffe1439a31447e5ed99533389fdb48b9 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 2.3E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS01580 ffe1439a31447e5ed99533389fdb48b9 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.3E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS01580 ffe1439a31447e5ed99533389fdb48b9 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 2.3E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS01580 ffe1439a31447e5ed99533389fdb48b9 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 2.3E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS01580 ffe1439a31447e5ed99533389fdb48b9 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 2.3E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS01580 ffe1439a31447e5ed99533389fdb48b9 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 2.3E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS01580 ffe1439a31447e5ed99533389fdb48b9 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 4.2E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS01580 ffe1439a31447e5ed99533389fdb48b9 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 4.2E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS01580 ffe1439a31447e5ed99533389fdb48b9 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 4.2E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS03270 a5350e9733a2e78582dc28654b225899 233 Hamap MF_00298 RNA pyrophosphohydrolase [rppH]. 1 156 37.605 T 29-03-2018 IPR022927 RNA pyrophosphohydrolase RppH CDC59_RS03270 a5350e9733a2e78582dc28654b225899 233 PRINTS PR00502 NUDIX hydrolase family signature 47 62 4.8E-7 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CDC59_RS03270 a5350e9733a2e78582dc28654b225899 233 PRINTS PR00502 NUDIX hydrolase family signature 33 47 4.8E-7 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CDC59_RS03270 a5350e9733a2e78582dc28654b225899 233 Gene3D G3DSA:3.90.79.10 1 163 2.0E-31 T 29-03-2018 CDC59_RS03270 a5350e9733a2e78582dc28654b225899 233 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CDC59_RS03270 a5350e9733a2e78582dc28654b225899 233 Pfam PF00293 NUDIX domain 7 136 6.8E-23 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CDC59_RS03270 a5350e9733a2e78582dc28654b225899 233 SUPERFAMILY SSF55811 6 166 1.9E-29 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CDC59_RS18860 2bb610bc26fc969732deac81c625be1b 119 Gene3D G3DSA:1.10.10.60 8 34 3.4E-9 T 29-03-2018 CDC59_RS18860 2bb610bc26fc969732deac81c625be1b 119 Pfam PF13384 Homeodomain-like domain 15 41 3.1E-6 T 29-03-2018 CDC59_RS18860 2bb610bc26fc969732deac81c625be1b 119 Gene3D G3DSA:1.10.10.10 35 93 4.4E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS00990 745b5dd22891ddcb1df08564c61beffd 375 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 3 369 1.5E-115 T 29-03-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 CDC59_RS00990 745b5dd22891ddcb1df08564c61beffd 375 Pfam PF01571 Aminomethyltransferase folate-binding domain 8 269 8.0E-82 T 29-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal CDC59_RS00990 745b5dd22891ddcb1df08564c61beffd 375 SUPERFAMILY SSF103025 3 286 5.83E-90 T 29-03-2018 CDC59_RS00990 745b5dd22891ddcb1df08564c61beffd 375 Gene3D G3DSA:3.30.1360.120 3 140 9.0E-33 T 29-03-2018 CDC59_RS00990 745b5dd22891ddcb1df08564c61beffd 375 PIRSF PIRSF006487 1 373 3.9E-78 T 29-03-2018 CDC59_RS00990 745b5dd22891ddcb1df08564c61beffd 375 Gene3D G3DSA:3.30.1360.120 149 246 8.5E-25 T 29-03-2018 CDC59_RS00990 745b5dd22891ddcb1df08564c61beffd 375 Hamap MF_00259 Aminomethyltransferase [gcvT]. 2 369 44.28 T 29-03-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CDC59_RS00990 745b5dd22891ddcb1df08564c61beffd 375 Gene3D G3DSA:4.10.1250.10 247 288 5.4E-15 T 29-03-2018 CDC59_RS00990 745b5dd22891ddcb1df08564c61beffd 375 SUPERFAMILY SSF101790 285 371 1.24E-21 T 29-03-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain CDC59_RS00990 745b5dd22891ddcb1df08564c61beffd 375 Gene3D G3DSA:2.40.30.110 289 374 4.5E-20 T 29-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CDC59_RS00990 745b5dd22891ddcb1df08564c61beffd 375 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 277 364 5.5E-16 T 29-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CDC59_RS10090 3737e4067ce32eaf3b9c42c3dccd97dd 491 SMART SM00729 23 221 8.8E-7 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CDC59_RS10090 3737e4067ce32eaf3b9c42c3dccd97dd 491 TIGRFAM TIGR03913 rad_SAM_trio: Y_X(10)_GDL-associated radical SAM protein 6 481 0.0 T 29-03-2018 IPR023820 Radical SAM GDL-associated CDC59_RS10090 3737e4067ce32eaf3b9c42c3dccd97dd 491 SUPERFAMILY SSF102114 18 339 9.68E-69 T 29-03-2018 CDC59_RS10090 3737e4067ce32eaf3b9c42c3dccd97dd 491 Gene3D G3DSA:3.20.20.70 11 371 3.9E-46 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS10090 3737e4067ce32eaf3b9c42c3dccd97dd 491 Pfam PF04055 Radical SAM superfamily 28 163 1.6E-20 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CDC59_RS10090 3737e4067ce32eaf3b9c42c3dccd97dd 491 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 265 356 2.7E-13 T 29-03-2018 IPR023885 4Fe4S-binding SPASM domain CDC59_RS10090 3737e4067ce32eaf3b9c42c3dccd97dd 491 Pfam PF13186 Iron-sulfur cluster-binding domain 265 329 1.7E-6 T 29-03-2018 IPR023885 4Fe4S-binding SPASM domain CDC59_RS07640 797d8a666bac803f530b3a456826e363 271 SUPERFAMILY SSF51556 2 260 9.81E-73 T 29-03-2018 IPR032466 Metal-dependent hydrolase CDC59_RS07640 797d8a666bac803f530b3a456826e363 271 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 191 207 - T 29-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 CDC59_RS07640 797d8a666bac803f530b3a456826e363 271 PIRSF PIRSF005902 1 264 5.7E-63 T 29-03-2018 IPR001130 TatD family GO:0016788 CDC59_RS07640 797d8a666bac803f530b3a456826e363 271 Gene3D G3DSA:3.20.20.140 1 264 2.6E-69 T 29-03-2018 CDC59_RS07640 797d8a666bac803f530b3a456826e363 271 Pfam PF01026 TatD related DNase 3 260 1.9E-61 T 29-03-2018 IPR001130 TatD family GO:0016788 CDC59_RS13140 45b5df898758c16689a2da8e4feb0a4e 292 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 2.3E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS13140 45b5df898758c16689a2da8e4feb0a4e 292 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 168 187 2.3E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS13140 45b5df898758c16689a2da8e4feb0a4e 292 Gene3D G3DSA:3.40.50.720 1 289 6.6E-63 T 29-03-2018 CDC59_RS13140 45b5df898758c16689a2da8e4feb0a4e 292 Pfam PF00106 short chain dehydrogenase 8 205 8.3E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS13140 45b5df898758c16689a2da8e4feb0a4e 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.4E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS13140 45b5df898758c16689a2da8e4feb0a4e 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 223 243 2.4E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS13140 45b5df898758c16689a2da8e4feb0a4e 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 2.4E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS13140 45b5df898758c16689a2da8e4feb0a4e 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 187 2.4E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS13140 45b5df898758c16689a2da8e4feb0a4e 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 206 2.4E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS13140 45b5df898758c16689a2da8e4feb0a4e 292 SUPERFAMILY SSF51735 2 282 1.63E-57 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS15920 282ef11626f667e0ca2c64a64dbded8d 531 Gene3D G3DSA:3.10.105.10 308 505 8.7E-50 T 29-03-2018 CDC59_RS15920 282ef11626f667e0ca2c64a64dbded8d 531 SUPERFAMILY SSF53850 31 518 1.16E-125 T 29-03-2018 CDC59_RS15920 282ef11626f667e0ca2c64a64dbded8d 531 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 77 445 4.3E-88 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CDC59_RS15920 282ef11626f667e0ca2c64a64dbded8d 531 PIRSF PIRSF002741 1 529 1.1E-98 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CDC59_RS15920 282ef11626f667e0ca2c64a64dbded8d 531 Gene3D G3DSA:3.90.76.10 44 183 3.3E-32 T 29-03-2018 CDC59_RS15920 282ef11626f667e0ca2c64a64dbded8d 531 Gene3D G3DSA:3.40.190.10 184 307 2.0E-34 T 29-03-2018 CDC59_RS19025 3eccf042eeafcde3a5f675d314bce530 122 Pfam PF10861 Protein of Unknown function (DUF2784) 4 119 1.1E-29 T 29-03-2018 IPR021218 Protein of unknown function DUF2784 CDC59_RS03680 64c8415aa0b749561e834137cf6c364c 370 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 4 357 1.5E-132 T 29-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 CDC59_RS03680 64c8415aa0b749561e834137cf6c364c 370 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 4 358 38.801 T 29-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 CDC59_RS03680 64c8415aa0b749561e834137cf6c364c 370 Gene3D G3DSA:2.30.30.280 210 277 5.1E-26 T 29-03-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 CDC59_RS03680 64c8415aa0b749561e834137cf6c364c 370 SUPERFAMILY SSF52402 2 241 3.31E-57 T 29-03-2018 CDC59_RS03680 64c8415aa0b749561e834137cf6c364c 370 Gene3D G3DSA:3.40.50.620 1 209 1.4E-63 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDC59_RS03680 64c8415aa0b749561e834137cf6c364c 370 Gene3D G3DSA:2.40.30.10 279 369 2.8E-27 T 29-03-2018 CDC59_RS03680 64c8415aa0b749561e834137cf6c364c 370 Pfam PF03054 tRNA methyl transferase 4 357 4.9E-133 T 29-03-2018 CDC59_RS23160 6a892ce2d568c99e8043da5bda1ddc45 442 SUPERFAMILY SSF103473 8 433 7.59E-78 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS23160 6a892ce2d568c99e8043da5bda1ddc45 442 Gene3D G3DSA:1.20.1250.20 13 210 1.4E-40 T 29-03-2018 CDC59_RS23160 6a892ce2d568c99e8043da5bda1ddc45 442 Gene3D G3DSA:1.20.1250.20 238 438 3.1E-24 T 29-03-2018 CDC59_RS23160 6a892ce2d568c99e8043da5bda1ddc45 442 Pfam PF07690 Major Facilitator Superfamily 30 398 4.0E-46 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDC59_RS23160 6a892ce2d568c99e8043da5bda1ddc45 442 ProSitePatterns PS00216 Sugar transport proteins signature 1. 79 95 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CDC59_RS19815 6e619c4d1480f7cdcdb8c6b48f027c95 295 SUPERFAMILY SSF46785 4 114 7.14E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS19815 6e619c4d1480f7cdcdb8c6b48f027c95 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 6.0E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS19815 6e619c4d1480f7cdcdb8c6b48f027c95 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 6.0E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS19815 6e619c4d1480f7cdcdb8c6b48f027c95 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 6.0E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS19815 6e619c4d1480f7cdcdb8c6b48f027c95 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 2.6E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS19815 6e619c4d1480f7cdcdb8c6b48f027c95 295 Gene3D G3DSA:3.40.190.10 91 178 1.6E-18 T 29-03-2018 CDC59_RS19815 6e619c4d1480f7cdcdb8c6b48f027c95 295 SUPERFAMILY SSF53850 91 292 1.52E-32 T 29-03-2018 CDC59_RS19815 6e619c4d1480f7cdcdb8c6b48f027c95 295 Pfam PF03466 LysR substrate binding domain 91 289 8.2E-33 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS19815 6e619c4d1480f7cdcdb8c6b48f027c95 295 Gene3D G3DSA:1.10.10.10 1 86 2.3E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS19815 6e619c4d1480f7cdcdb8c6b48f027c95 295 Gene3D G3DSA:3.40.190.10 179 268 1.2E-15 T 29-03-2018 CDC59_RS18205 333d560649203b538f9560ff9b8ead82 566 Pfam PF01740 STAS domain 450 537 2.3E-9 T 29-03-2018 IPR002645 STAS domain CDC59_RS18205 333d560649203b538f9560ff9b8ead82 566 Pfam PF00916 Sulfate permease family 34 380 8.8E-63 T 29-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 CDC59_RS18205 333d560649203b538f9560ff9b8ead82 566 SUPERFAMILY SSF52091 448 540 5.89E-10 T 29-03-2018 IPR002645 STAS domain CDC59_RS18205 333d560649203b538f9560ff9b8ead82 566 Gene3D G3DSA:3.30.750.24 427 562 3.0E-19 T 29-03-2018 IPR002645 STAS domain CDC59_RS14840 b65596d3928d6b1dc2f010236951faa8 346 Gene3D G3DSA:3.20.20.330 7 342 2.3E-116 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CDC59_RS14840 b65596d3928d6b1dc2f010236951faa8 346 Pfam PF02574 Homocysteine S-methyltransferase 22 330 2.2E-81 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CDC59_RS14840 b65596d3928d6b1dc2f010236951faa8 346 PIRSF PIRSF037505 60 343 2.0E-9 T 29-03-2018 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 Reactome: R-HSA-1614635 CDC59_RS14840 b65596d3928d6b1dc2f010236951faa8 346 SUPERFAMILY SSF82282 13 341 3.4E-101 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CDC59_RS02485 014ad2727fd54fbf666f997c4d7a9641 368 PIRSF PIRSF001455 4 360 7.8E-110 T 29-03-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CDC59_RS02485 014ad2727fd54fbf666f997c4d7a9641 368 Gene3D G3DSA:1.20.1090.10 173 358 1.9E-66 T 29-03-2018 CDC59_RS02485 014ad2727fd54fbf666f997c4d7a9641 368 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 13 350 1.8E-123 T 29-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CDC59_RS02485 014ad2727fd54fbf666f997c4d7a9641 368 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 2 357 43.145 T 29-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CDC59_RS02485 014ad2727fd54fbf666f997c4d7a9641 368 Pfam PF01761 3-dehydroquinate synthase 67 324 4.0E-107 T 29-03-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CDC59_RS02485 014ad2727fd54fbf666f997c4d7a9641 368 SUPERFAMILY SSF56796 4 354 4.19E-120 T 29-03-2018 CDC59_RS02485 014ad2727fd54fbf666f997c4d7a9641 368 Gene3D G3DSA:3.40.50.1970 8 172 5.4E-56 T 29-03-2018 CDC59_RS21480 0ade8296d2eabe349fa5b8c2a8e6dd69 277 SMART SM00858 47 107 7.5E-7 T 29-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 CDC59_RS21480 0ade8296d2eabe349fa5b8c2a8e6dd69 277 Gene3D G3DSA:3.90.1210.10 47 108 3.5E-7 T 29-03-2018 CDC59_RS21480 0ade8296d2eabe349fa5b8c2a8e6dd69 277 Pfam PF16976 Flp pilus assembly protein RcpC/CpaB 109 171 8.9E-19 T 29-03-2018 IPR031571 Flp pilus assembly protein RcpC/CpaB domain CDC59_RS21480 0ade8296d2eabe349fa5b8c2a8e6dd69 277 Pfam PF08666 SAF domain 48 106 7.9E-6 T 29-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 CDC59_RS21480 0ade8296d2eabe349fa5b8c2a8e6dd69 277 TIGRFAM TIGR03177 pilus_cpaB: Flp pilus assembly protein CpaB 13 171 5.8E-35 T 29-03-2018 IPR017592 Pilus assembly, Flp-type CpaB CDC59_RS08460 097ba57a334f9a42386c8d0fd74ae33d 252 SUPERFAMILY SSF51695 11 247 7.59E-63 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CDC59_RS08460 097ba57a334f9a42386c8d0fd74ae33d 252 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 18 245 2.2E-37 T 29-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CDC59_RS08460 097ba57a334f9a42386c8d0fd74ae33d 252 Gene3D G3DSA:3.20.20.190 1 249 2.6E-61 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CDC59_RS20145 eb1c4ef0d43cc7ef09d65a607a744b30 151 Gene3D G3DSA:3.30.1460.10 4 130 1.1E-28 T 29-03-2018 CDC59_RS20145 eb1c4ef0d43cc7ef09d65a607a744b30 151 SUPERFAMILY SSF69635 7 129 2.2E-9 T 29-03-2018 CDC59_RS20145 eb1c4ef0d43cc7ef09d65a607a744b30 151 Pfam PF05932 Tir chaperone protein (CesT) family 9 127 4.2E-5 T 29-03-2018 IPR010261 Tir chaperone protein (CesT) family GO:0005737|GO:0050708 CDC59_RS07165 58e1c4388e933c023a354cff545fc8c2 176 TIGRFAM TIGR00714 hscB: Fe-S protein assembly co-chaperone HscB 18 173 2.6E-30 T 29-03-2018 IPR004640 Co-chaperone Hsc20 GO:0001671|GO:0051087|GO:0097428 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 CDC59_RS07165 58e1c4388e933c023a354cff545fc8c2 176 SMART SM00271 6 71 3.9E-5 T 29-03-2018 IPR001623 DnaJ domain CDC59_RS07165 58e1c4388e933c023a354cff545fc8c2 176 SUPERFAMILY SSF47144 82 176 6.28E-23 T 29-03-2018 IPR009073 Co-chaperone HscB, C-terminal oligomerisation domain GO:0051259 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 CDC59_RS07165 58e1c4388e933c023a354cff545fc8c2 176 Gene3D G3DSA:1.10.287.110 1 89 4.5E-11 T 29-03-2018 IPR001623 DnaJ domain CDC59_RS07165 58e1c4388e933c023a354cff545fc8c2 176 Hamap MF_00682 Co-chaperone protein HscB [hscB]. 6 175 23.663 T 29-03-2018 IPR004640 Co-chaperone Hsc20 GO:0001671|GO:0051087|GO:0097428 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 CDC59_RS07165 58e1c4388e933c023a354cff545fc8c2 176 Gene3D G3DSA:1.20.1280.20 90 176 8.5E-21 T 29-03-2018 IPR009073 Co-chaperone HscB, C-terminal oligomerisation domain GO:0051259 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 CDC59_RS07165 58e1c4388e933c023a354cff545fc8c2 176 Pfam PF07743 HSCB C-terminal oligomerisation domain 92 166 3.8E-16 T 29-03-2018 IPR009073 Co-chaperone HscB, C-terminal oligomerisation domain GO:0051259 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 CDC59_RS07165 58e1c4388e933c023a354cff545fc8c2 176 SUPERFAMILY SSF46565 7 79 4.84E-18 T 29-03-2018 IPR001623 DnaJ domain CDC59_RS00440 e6d6d52f2b224b28c8cc3db24e990df9 141 Gene3D G3DSA:3.30.530.20 4 139 7.5E-14 T 29-03-2018 IPR023393 START-like domain CDC59_RS00440 e6d6d52f2b224b28c8cc3db24e990df9 141 SUPERFAMILY SSF55961 2 138 3.53E-28 T 29-03-2018 CDC59_RS11845 91a55eaed97c359896907b4048acefa8 89 Gene3D G3DSA:1.10.287.10 2 89 1.5E-35 T 29-03-2018 CDC59_RS11845 91a55eaed97c359896907b4048acefa8 89 SUPERFAMILY SSF47060 5 89 4.12E-35 T 29-03-2018 IPR009068 S15/NS1, RNA-binding CDC59_RS11845 91a55eaed97c359896907b4048acefa8 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 1 89 21.943 T 29-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS11845 91a55eaed97c359896907b4048acefa8 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 29-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS11845 91a55eaed97c359896907b4048acefa8 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 10 88 9.0E-34 T 29-03-2018 CDC59_RS11845 91a55eaed97c359896907b4048acefa8 89 Pfam PF00312 Ribosomal protein S15 8 88 3.9E-38 T 29-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS11845 91a55eaed97c359896907b4048acefa8 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 6 89 1.2E-38 T 29-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS11845 91a55eaed97c359896907b4048acefa8 89 SMART SM01387 8 88 1.5E-53 T 29-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS17975 2962cf33fd2cc36fa3c3706a2f093f10 304 Gene3D G3DSA:3.40.190.10 94 178 8.9E-18 T 29-03-2018 CDC59_RS17975 2962cf33fd2cc36fa3c3706a2f093f10 304 SUPERFAMILY SSF46785 6 116 7.07E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS17975 2962cf33fd2cc36fa3c3706a2f093f10 304 Pfam PF03466 LysR substrate binding domain 93 300 3.0E-43 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS17975 2962cf33fd2cc36fa3c3706a2f093f10 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 69 2.7E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS17975 2962cf33fd2cc36fa3c3706a2f093f10 304 Gene3D G3DSA:3.40.190.10 179 269 1.8E-26 T 29-03-2018 CDC59_RS17975 2962cf33fd2cc36fa3c3706a2f093f10 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 3.6E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS17975 2962cf33fd2cc36fa3c3706a2f093f10 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 3.6E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS17975 2962cf33fd2cc36fa3c3706a2f093f10 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 3.6E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS17975 2962cf33fd2cc36fa3c3706a2f093f10 304 SUPERFAMILY SSF53850 95 301 2.17E-45 T 29-03-2018 CDC59_RS17975 2962cf33fd2cc36fa3c3706a2f093f10 304 Gene3D G3DSA:1.10.10.10 2 93 5.1E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS19155 179931aa91dfe23d4c0b55c5b7e43bd2 332 SUPERFAMILY SSF53756 2 302 2.04E-64 T 29-03-2018 CDC59_RS19155 179931aa91dfe23d4c0b55c5b7e43bd2 332 TIGRFAM TIGR02193 heptsyl_trn_I: lipopolysaccharide heptosyltransferase I 3 319 1.6E-105 T 29-03-2018 IPR011908 Lipopolysaccharide heptosyltransferase I GO:0008920|GO:0009244 CDC59_RS19155 179931aa91dfe23d4c0b55c5b7e43bd2 332 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 76 296 9.2E-40 T 29-03-2018 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 CDC59_RS19155 179931aa91dfe23d4c0b55c5b7e43bd2 332 Gene3D G3DSA:3.40.50.2000 1 158 1.0E-35 T 29-03-2018 CDC59_RS19155 179931aa91dfe23d4c0b55c5b7e43bd2 332 Gene3D G3DSA:3.40.50.2000 171 320 6.2E-25 T 29-03-2018 CDC59_RS20300 7e31ec2f0fa1d2010d8cf16a3f0b014e 139 SUPERFAMILY SSF54427 5 129 1.6E-17 T 29-03-2018 IPR032710 NTF2-like domain CDC59_RS20300 7e31ec2f0fa1d2010d8cf16a3f0b014e 139 Gene3D G3DSA:3.10.450.50 4 132 5.0E-17 T 29-03-2018 CDC59_RS20300 7e31ec2f0fa1d2010d8cf16a3f0b014e 139 Pfam PF12680 SnoaL-like domain 9 107 4.8E-10 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CDC59_RS00475 91868d213e1932b51d75999cae442874 224 SMART SM00448 1 112 2.4E-38 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS00475 91868d213e1932b51d75999cae442874 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 218 1.4E-15 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDC59_RS00475 91868d213e1932b51d75999cae442874 224 SMART SM00862 145 218 9.4E-15 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDC59_RS00475 91868d213e1932b51d75999cae442874 224 SUPERFAMILY SSF52172 1 165 3.7E-38 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS00475 91868d213e1932b51d75999cae442874 224 Pfam PF00072 Response regulator receiver domain 4 113 5.4E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS00475 91868d213e1932b51d75999cae442874 224 Gene3D G3DSA:1.10.10.10 122 224 2.0E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS00475 91868d213e1932b51d75999cae442874 224 Gene3D G3DSA:3.40.50.2300 1 121 4.3E-34 T 29-03-2018 CDC59_RS23190 8353b45d65faa2490220bb6be671a091 309 SUPERFAMILY SSF48179 166 272 5.27E-28 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CDC59_RS23190 8353b45d65faa2490220bb6be671a091 309 SUPERFAMILY SSF51735 5 162 3.12E-30 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS23190 8353b45d65faa2490220bb6be671a091 309 PIRSF PIRSF000103 1 217 2.3E-17 T 29-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CDC59_RS23190 8353b45d65faa2490220bb6be671a091 309 PIRSF PIRSF000103 225 270 260.0 T 29-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CDC59_RS23190 8353b45d65faa2490220bb6be671a091 309 Pfam PF09130 Domain of unknown function (DUF1932) 193 264 6.8E-18 T 29-03-2018 IPR015814 Phosphogluconate dehydrogenase, NAD-binding, putative, C-terminal CDC59_RS23190 8353b45d65faa2490220bb6be671a091 309 Gene3D G3DSA:3.40.50.720 5 172 2.9E-16 T 29-03-2018 CDC59_RS23190 8353b45d65faa2490220bb6be671a091 309 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 6 125 5.3E-9 T 29-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CDC59_RS23190 8353b45d65faa2490220bb6be671a091 309 Gene3D G3DSA:1.10.1040.10 175 291 1.6E-36 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CDC59_RS20445 02cf49df73c3cb3815c3a996c74481b3 455 SMART SM00878 336 441 4.8E-61 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CDC59_RS20445 02cf49df73c3cb3815c3a996c74481b3 455 Gene3D G3DSA:3.30.470.20 211 444 9.7E-95 T 29-03-2018 CDC59_RS20445 02cf49df73c3cb3815c3a996c74481b3 455 Gene3D G3DSA:3.40.50.20 1 123 1.8E-50 T 29-03-2018 CDC59_RS20445 02cf49df73c3cb3815c3a996c74481b3 455 SUPERFAMILY SSF52440 1 113 6.26E-46 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CDC59_RS20445 02cf49df73c3cb3815c3a996c74481b3 455 SUPERFAMILY SSF56059 83 344 1.04E-68 T 29-03-2018 CDC59_RS20445 02cf49df73c3cb3815c3a996c74481b3 455 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 444 6.1E-201 T 29-03-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 CDC59_RS20445 02cf49df73c3cb3815c3a996c74481b3 455 SUPERFAMILY SSF51246 331 444 1.41E-41 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CDC59_RS20445 02cf49df73c3cb3815c3a996c74481b3 455 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 322 1.6E-75 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CDC59_RS20445 02cf49df73c3cb3815c3a996c74481b3 455 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 154 168 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CDC59_RS20445 02cf49df73c3cb3815c3a996c74481b3 455 Gene3D G3DSA:3.30.1490.20 124 210 9.3E-23 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CDC59_RS20445 02cf49df73c3cb3815c3a996c74481b3 455 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 3.1E-42 T 29-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CDC59_RS20445 02cf49df73c3cb3815c3a996c74481b3 455 Pfam PF02785 Biotin carboxylase C-terminal domain 336 442 5.3E-38 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CDC59_RS20445 02cf49df73c3cb3815c3a996c74481b3 455 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CDC59_RS11560 69b4cd5b62a72718755ad25a80299c16 394 Gene3D G3DSA:3.90.1150.10 307 394 1.4E-16 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS11560 69b4cd5b62a72718755ad25a80299c16 394 Pfam PF00155 Aminotransferase class I and II 41 391 3.9E-63 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CDC59_RS11560 69b4cd5b62a72718755ad25a80299c16 394 Gene3D G3DSA:3.40.640.10 55 306 2.1E-63 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDC59_RS11560 69b4cd5b62a72718755ad25a80299c16 394 SUPERFAMILY SSF53383 19 393 1.6E-105 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS10885 3ff3941c861298f3dc00b38798931f5b 512 Gene3D G3DSA:3.30.420.40 2 129 1.5E-36 T 29-03-2018 CDC59_RS10885 3ff3941c861298f3dc00b38798931f5b 512 SUPERFAMILY SSF109604 322 510 3.14E-42 T 29-03-2018 CDC59_RS10885 3ff3941c861298f3dc00b38798931f5b 512 PIRSF PIRSF001267 1 512 3.0E-196 T 29-03-2018 IPR030673 Pyrophosphatase, GppA/Ppx-type KEGG: 00230+3.6.1.40 CDC59_RS10885 3ff3941c861298f3dc00b38798931f5b 512 SUPERFAMILY SSF53067 7 135 2.98E-30 T 29-03-2018 CDC59_RS10885 3ff3941c861298f3dc00b38798931f5b 512 Gene3D G3DSA:3.30.420.150 130 314 1.7E-35 T 29-03-2018 CDC59_RS10885 3ff3941c861298f3dc00b38798931f5b 512 Pfam PF02541 Ppx/GppA phosphatase family 42 316 5.3E-68 T 29-03-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 CDC59_RS10885 3ff3941c861298f3dc00b38798931f5b 512 TIGRFAM TIGR03706 exo_poly_only: exopolyphosphatase 8 315 7.3E-95 T 29-03-2018 IPR022371 Exopolyphosphatase GO:0004309|GO:0006793 CDC59_RS10885 3ff3941c861298f3dc00b38798931f5b 512 SUPERFAMILY SSF53067 142 319 1.5E-42 T 29-03-2018 CDC59_RS08985 f85447a86ba5bbd7cce5040f18debd6d 454 PRINTS PR01874 DNA repair protein radA signature 10 34 3.3E-95 T 29-03-2018 CDC59_RS08985 f85447a86ba5bbd7cce5040f18debd6d 454 PRINTS PR01874 DNA repair protein radA signature 78 106 3.3E-95 T 29-03-2018 CDC59_RS08985 f85447a86ba5bbd7cce5040f18debd6d 454 PRINTS PR01874 DNA repair protein radA signature 119 136 3.3E-95 T 29-03-2018 CDC59_RS08985 f85447a86ba5bbd7cce5040f18debd6d 454 PRINTS PR01874 DNA repair protein radA signature 208 236 3.3E-95 T 29-03-2018 CDC59_RS08985 f85447a86ba5bbd7cce5040f18debd6d 454 PRINTS PR01874 DNA repair protein radA signature 243 269 3.3E-95 T 29-03-2018 CDC59_RS08985 f85447a86ba5bbd7cce5040f18debd6d 454 PRINTS PR01874 DNA repair protein radA signature 317 340 3.3E-95 T 29-03-2018 CDC59_RS08985 f85447a86ba5bbd7cce5040f18debd6d 454 PRINTS PR01874 DNA repair protein radA signature 169 193 3.3E-95 T 29-03-2018 CDC59_RS08985 f85447a86ba5bbd7cce5040f18debd6d 454 SUPERFAMILY SSF52540 64 285 2.21E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS08985 f85447a86ba5bbd7cce5040f18debd6d 454 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 446 5.3E-196 T 29-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 CDC59_RS08985 f85447a86ba5bbd7cce5040f18debd6d 454 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 360 446 2.6E-4 T 29-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 CDC59_RS08985 f85447a86ba5bbd7cce5040f18debd6d 454 SMART SM00382 86 239 9.3E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS08985 f85447a86ba5bbd7cce5040f18debd6d 454 SUPERFAMILY SSF54211 250 264 7.59E-41 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CDC59_RS08985 f85447a86ba5bbd7cce5040f18debd6d 454 SUPERFAMILY SSF54211 298 451 7.59E-41 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CDC59_RS08985 f85447a86ba5bbd7cce5040f18debd6d 454 Pfam PF13481 AAA domain 78 217 1.2E-18 T 29-03-2018 CDC59_RS08985 f85447a86ba5bbd7cce5040f18debd6d 454 Hamap MF_01498 DNA repair protein RadA [radA]. 21 450 44.112 T 29-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 CDC59_RS08985 f85447a86ba5bbd7cce5040f18debd6d 454 Gene3D G3DSA:3.30.230.10 242 454 8.8E-45 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CDC59_RS08985 f85447a86ba5bbd7cce5040f18debd6d 454 Gene3D G3DSA:3.40.50.300 56 241 1.7E-19 T 29-03-2018 CDC59_RS19425 e8e2c7c037f49d9b626eaa6d40a12fdf 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 1.6E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS19425 e8e2c7c037f49d9b626eaa6d40a12fdf 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 1.6E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS19425 e8e2c7c037f49d9b626eaa6d40a12fdf 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 1.6E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS19425 e8e2c7c037f49d9b626eaa6d40a12fdf 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 67 7.2E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS19425 e8e2c7c037f49d9b626eaa6d40a12fdf 309 SUPERFAMILY SSF46785 4 86 2.38E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS19425 e8e2c7c037f49d9b626eaa6d40a12fdf 309 Gene3D G3DSA:3.40.190.10 188 275 7.3E-13 T 29-03-2018 CDC59_RS19425 e8e2c7c037f49d9b626eaa6d40a12fdf 309 Gene3D G3DSA:1.10.10.10 3 92 3.9E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS19425 e8e2c7c037f49d9b626eaa6d40a12fdf 309 SUPERFAMILY SSF53850 91 301 2.02E-36 T 29-03-2018 CDC59_RS19425 e8e2c7c037f49d9b626eaa6d40a12fdf 309 Pfam PF03466 LysR substrate binding domain 98 304 1.3E-19 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS19425 e8e2c7c037f49d9b626eaa6d40a12fdf 309 Gene3D G3DSA:3.40.190.10 95 187 4.1E-10 T 29-03-2018 CDC59_RS16020 2b6329ebcd7b4332bc194cfff897d6b1 386 Gene3D G3DSA:3.40.50.2300 154 315 2.6E-38 T 29-03-2018 CDC59_RS16020 2b6329ebcd7b4332bc194cfff897d6b1 386 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 52 68 5.8E-11 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CDC59_RS16020 2b6329ebcd7b4332bc194cfff897d6b1 386 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 93 103 5.8E-11 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CDC59_RS16020 2b6329ebcd7b4332bc194cfff897d6b1 386 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 30 46 5.8E-11 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CDC59_RS16020 2b6329ebcd7b4332bc194cfff897d6b1 386 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 259 277 5.8E-11 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CDC59_RS16020 2b6329ebcd7b4332bc194cfff897d6b1 386 Pfam PF13458 Periplasmic binding protein 30 362 5.9E-64 T 29-03-2018 IPR028081 Leucine-binding protein domain CDC59_RS16020 2b6329ebcd7b4332bc194cfff897d6b1 386 Gene3D G3DSA:3.40.50.2300 13 153 1.6E-23 T 29-03-2018 CDC59_RS16020 2b6329ebcd7b4332bc194cfff897d6b1 386 SUPERFAMILY SSF53822 30 357 2.12E-83 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CDC59_RS14655 895c00faf1a6f3338313600aedd1bead 320 Gene3D G3DSA:3.40.190.10 86 184 4.9E-19 T 29-03-2018 CDC59_RS14655 895c00faf1a6f3338313600aedd1bead 320 Gene3D G3DSA:1.10.10.10 10 85 3.9E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS14655 895c00faf1a6f3338313600aedd1bead 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 28 39 3.6E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS14655 895c00faf1a6f3338313600aedd1bead 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 49 3.6E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS14655 895c00faf1a6f3338313600aedd1bead 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 49 60 3.6E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS14655 895c00faf1a6f3338313600aedd1bead 320 SUPERFAMILY SSF46785 8 92 9.19E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS14655 895c00faf1a6f3338313600aedd1bead 320 Gene3D G3DSA:3.40.190.10 185 264 1.3E-15 T 29-03-2018 CDC59_RS14655 895c00faf1a6f3338313600aedd1bead 320 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 14 72 4.8E-21 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS14655 895c00faf1a6f3338313600aedd1bead 320 SUPERFAMILY SSF53850 99 299 6.83E-41 T 29-03-2018 CDC59_RS14655 895c00faf1a6f3338313600aedd1bead 320 Pfam PF03466 LysR substrate binding domain 98 294 4.6E-37 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS21435 e891e78c5fdde290a9ab5d9f3882e50b 465 Pfam PF02954 Bacterial regulatory protein, Fis family 416 452 6.7E-11 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CDC59_RS21435 e891e78c5fdde290a9ab5d9f3882e50b 465 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 418 435 1.9E-5 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CDC59_RS21435 e891e78c5fdde290a9ab5d9f3882e50b 465 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 435 455 1.9E-5 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CDC59_RS21435 e891e78c5fdde290a9ab5d9f3882e50b 465 SUPERFAMILY SSF52540 137 369 5.83E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS21435 e891e78c5fdde290a9ab5d9f3882e50b 465 Pfam PF00158 Sigma-54 interaction domain 138 304 6.2E-60 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CDC59_RS21435 e891e78c5fdde290a9ab5d9f3882e50b 465 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 161 174 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CDC59_RS21435 e891e78c5fdde290a9ab5d9f3882e50b 465 Gene3D G3DSA:1.10.10.60 389 458 8.9E-11 T 29-03-2018 CDC59_RS21435 e891e78c5fdde290a9ab5d9f3882e50b 465 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 224 239 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CDC59_RS21435 e891e78c5fdde290a9ab5d9f3882e50b 465 SUPERFAMILY SSF46689 412 454 3.33E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS21435 e891e78c5fdde290a9ab5d9f3882e50b 465 SMART SM00382 157 301 7.2E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS21435 e891e78c5fdde290a9ab5d9f3882e50b 465 Gene3D G3DSA:3.40.50.300 132 310 9.8E-22 T 29-03-2018 CDC59_RS21435 e891e78c5fdde290a9ab5d9f3882e50b 465 Gene3D G3DSA:1.10.8.60 314 384 4.5E-4 T 29-03-2018 CDC59_RS13635 38e1d1528e5949a77f87780b98589a56 301 SUPERFAMILY SSF103481 198 301 3.79E-12 T 29-03-2018 CDC59_RS13635 38e1d1528e5949a77f87780b98589a56 301 SUPERFAMILY SSF103481 50 151 2.09E-13 T 29-03-2018 CDC59_RS13635 38e1d1528e5949a77f87780b98589a56 301 Pfam PF00892 EamA-like transporter family 163 299 1.3E-16 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CDC59_RS13635 38e1d1528e5949a77f87780b98589a56 301 Pfam PF00892 EamA-like transporter family 17 147 1.1E-18 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CDC59_RS01430 025d60eb8f772aa7ca1a5c9d4bca0258 247 Gene3D G3DSA:3.90.470.20 117 233 1.8E-8 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CDC59_RS01430 025d60eb8f772aa7ca1a5c9d4bca0258 247 Gene3D G3DSA:3.90.470.20 2 116 9.7E-20 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CDC59_RS01430 025d60eb8f772aa7ca1a5c9d4bca0258 247 SUPERFAMILY SSF56214 106 212 4.84E-18 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CDC59_RS01430 025d60eb8f772aa7ca1a5c9d4bca0258 247 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 107 181 9.6E-11 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CDC59_RS01430 025d60eb8f772aa7ca1a5c9d4bca0258 247 SUPERFAMILY SSF56214 16 98 1.91E-16 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CDC59_RS09760 5833ed0639b40e371d6a8a91c7f9738b 300 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 1.6E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS09760 5833ed0639b40e371d6a8a91c7f9738b 300 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.6E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS09760 5833ed0639b40e371d6a8a91c7f9738b 300 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 1.6E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS09760 5833ed0639b40e371d6a8a91c7f9738b 300 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 5.8E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS09760 5833ed0639b40e371d6a8a91c7f9738b 300 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 5.8E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS09760 5833ed0639b40e371d6a8a91c7f9738b 300 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 5.8E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS09760 5833ed0639b40e371d6a8a91c7f9738b 300 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 5.8E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS09760 5833ed0639b40e371d6a8a91c7f9738b 300 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 5.8E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS09760 5833ed0639b40e371d6a8a91c7f9738b 300 Pfam PF00106 short chain dehydrogenase 8 206 5.3E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS09760 5833ed0639b40e371d6a8a91c7f9738b 300 Gene3D G3DSA:3.40.50.720 1 285 6.3E-51 T 29-03-2018 CDC59_RS09760 5833ed0639b40e371d6a8a91c7f9738b 300 SUPERFAMILY SSF51735 2 258 9.64E-55 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS05805 f1a5a35515ef9b72beca23d2e9a2871c 283 Gene3D G3DSA:3.40.190.10 88 175 4.2E-18 T 29-03-2018 CDC59_RS05805 f1a5a35515ef9b72beca23d2e9a2871c 283 Pfam PF03466 LysR substrate binding domain 89 271 9.5E-41 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS05805 f1a5a35515ef9b72beca23d2e9a2871c 283 Gene3D G3DSA:3.40.190.10 176 263 2.1E-25 T 29-03-2018 CDC59_RS05805 f1a5a35515ef9b72beca23d2e9a2871c 283 SUPERFAMILY SSF46785 4 112 4.52E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS05805 f1a5a35515ef9b72beca23d2e9a2871c 283 SUPERFAMILY SSF53850 90 273 9.41E-42 T 29-03-2018 CDC59_RS05805 f1a5a35515ef9b72beca23d2e9a2871c 283 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 2.1E-13 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS05805 f1a5a35515ef9b72beca23d2e9a2871c 283 Gene3D G3DSA:1.10.10.10 3 84 2.7E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS10055 7cbc47daae2eeffceb811f0c7170b4bb 472 SMART SM00387 351 467 1.1E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS10055 7cbc47daae2eeffceb811f0c7170b4bb 472 Gene3D G3DSA:1.10.287.130 223 302 1.8E-10 T 29-03-2018 CDC59_RS10055 7cbc47daae2eeffceb811f0c7170b4bb 472 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 354 463 1.6E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS10055 7cbc47daae2eeffceb811f0c7170b4bb 472 Gene3D G3DSA:3.30.565.10 311 470 5.1E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS10055 7cbc47daae2eeffceb811f0c7170b4bb 472 Gene3D G3DSA:1.20.5.1040 138 188 0.33 T 29-03-2018 CDC59_RS10055 7cbc47daae2eeffceb811f0c7170b4bb 472 Gene3D G3DSA:1.20.5.1040 4 53 6.5E-5 T 29-03-2018 CDC59_RS10055 7cbc47daae2eeffceb811f0c7170b4bb 472 SMART SM00388 241 306 1.9E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS10055 7cbc47daae2eeffceb811f0c7170b4bb 472 Pfam PF00512 His Kinase A (phospho-acceptor) domain 242 304 2.2E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS10055 7cbc47daae2eeffceb811f0c7170b4bb 472 Pfam PF08521 Two-component sensor kinase N-terminal 18 164 2.4E-40 T 29-03-2018 IPR013727 Two-component sensor kinase, N-terminal CDC59_RS10055 7cbc47daae2eeffceb811f0c7170b4bb 472 PRINTS PR00344 Bacterial sensor protein C-terminal signature 427 445 4.2E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS10055 7cbc47daae2eeffceb811f0c7170b4bb 472 PRINTS PR00344 Bacterial sensor protein C-terminal signature 393 407 4.2E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS10055 7cbc47daae2eeffceb811f0c7170b4bb 472 PRINTS PR00344 Bacterial sensor protein C-terminal signature 411 421 4.2E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS10055 7cbc47daae2eeffceb811f0c7170b4bb 472 SUPERFAMILY SSF55874 296 463 2.36E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS10055 7cbc47daae2eeffceb811f0c7170b4bb 472 SUPERFAMILY SSF47384 224 305 5.1E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS22920 98c28f34bec8752d9520aa3097e9a0a5 380 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 32 48 1.0E-6 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CDC59_RS22920 98c28f34bec8752d9520aa3097e9a0a5 380 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 54 70 1.0E-6 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CDC59_RS22920 98c28f34bec8752d9520aa3097e9a0a5 380 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 339 354 1.0E-6 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CDC59_RS22920 98c28f34bec8752d9520aa3097e9a0a5 380 Gene3D G3DSA:3.40.50.2300 161 293 7.6E-32 T 29-03-2018 CDC59_RS22920 98c28f34bec8752d9520aa3097e9a0a5 380 Gene3D G3DSA:3.40.50.2300 294 374 8.3E-10 T 29-03-2018 CDC59_RS22920 98c28f34bec8752d9520aa3097e9a0a5 380 Gene3D G3DSA:3.40.50.2300 30 160 4.6E-17 T 29-03-2018 CDC59_RS22920 98c28f34bec8752d9520aa3097e9a0a5 380 SUPERFAMILY SSF53822 31 377 1.07E-86 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CDC59_RS22920 98c28f34bec8752d9520aa3097e9a0a5 380 Pfam PF13458 Periplasmic binding protein 31 372 1.4E-51 T 29-03-2018 IPR028081 Leucine-binding protein domain CDC59_RS06925 880b9845cf5c93fe2085a8f388c7f858 387 Gene3D G3DSA:3.40.190.10 1 364 1.8E-5 T 29-03-2018 CDC59_RS06925 880b9845cf5c93fe2085a8f388c7f858 387 Pfam PF14321 Domain of unknown function (DUF4382) 32 183 2.3E-38 T 29-03-2018 IPR025491 Domain of unknown function DUF4382 CDC59_RS21010 ba36bbcd7d8c856f472d272ced02eedf 539 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 111 437 1.6E-67 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CDC59_RS21010 ba36bbcd7d8c856f472d272ced02eedf 539 Gene3D G3DSA:3.40.190.10 211 304 1.9E-23 T 29-03-2018 CDC59_RS21010 ba36bbcd7d8c856f472d272ced02eedf 539 SUPERFAMILY SSF53850 59 528 1.25E-113 T 29-03-2018 CDC59_RS21010 ba36bbcd7d8c856f472d272ced02eedf 539 Gene3D G3DSA:3.90.76.10 77 210 4.0E-31 T 29-03-2018 CDC59_RS21010 ba36bbcd7d8c856f472d272ced02eedf 539 PIRSF PIRSF002741 25 538 1.3E-73 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CDC59_RS21010 ba36bbcd7d8c856f472d272ced02eedf 539 Gene3D G3DSA:3.10.105.10 305 502 1.1E-32 T 29-03-2018 CDC59_RS23920 67b36bc341f8894483becb012c1a248a 55 Pfam PF07043 Protein of unknown function (DUF1328) 6 44 2.3E-15 T 29-03-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 CDC59_RS23920 67b36bc341f8894483becb012c1a248a 55 Hamap MF_01361 UPF0391 membrane protein YtjA [ytjA]. 1 50 20.082 T 29-03-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 CDC59_RS23920 67b36bc341f8894483becb012c1a248a 55 PIRSF PIRSF036466 1 55 1.4E-20 T 29-03-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 CDC59_RS13660 add13a9a615aeb268aa5a79f47a2f776 352 Gene3D G3DSA:3.90.1200.10 105 351 3.5E-38 T 29-03-2018 CDC59_RS13660 add13a9a615aeb268aa5a79f47a2f776 352 Gene3D G3DSA:3.30.200.20 11 104 6.6E-30 T 29-03-2018 CDC59_RS13660 add13a9a615aeb268aa5a79f47a2f776 352 SUPERFAMILY SSF56112 18 338 8.29E-54 T 29-03-2018 IPR011009 Protein kinase-like domain CDC59_RS13660 add13a9a615aeb268aa5a79f47a2f776 352 Pfam PF01636 Phosphotransferase enzyme family 36 267 2.8E-34 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase CDC59_RS06050 ed9b525d9f7270a12f39d7209e9a047a 970 SUPERFAMILY SSF50677 197 363 1.12E-54 T 29-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CDC59_RS06050 ed9b525d9f7270a12f39d7209e9a047a 970 Pfam PF08264 Anticodon-binding domain of tRNA 687 841 1.1E-40 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CDC59_RS06050 ed9b525d9f7270a12f39d7209e9a047a 970 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 22 636 2.7E-200 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDC59_RS06050 ed9b525d9f7270a12f39d7209e9a047a 970 Gene3D G3DSA:1.10.730.10 625 807 5.4E-54 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDC59_RS06050 ed9b525d9f7270a12f39d7209e9a047a 970 Gene3D G3DSA:1.10.287.380 896 964 2.2E-22 T 29-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 CDC59_RS06050 ed9b525d9f7270a12f39d7209e9a047a 970 PRINTS PR00986 Valyl-tRNA synthetase signature 480 501 2.3E-35 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CDC59_RS06050 ed9b525d9f7270a12f39d7209e9a047a 970 PRINTS PR00986 Valyl-tRNA synthetase signature 367 380 2.3E-35 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CDC59_RS06050 ed9b525d9f7270a12f39d7209e9a047a 970 PRINTS PR00986 Valyl-tRNA synthetase signature 241 258 2.3E-35 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CDC59_RS06050 ed9b525d9f7270a12f39d7209e9a047a 970 PRINTS PR00986 Valyl-tRNA synthetase signature 42 53 2.3E-35 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CDC59_RS06050 ed9b525d9f7270a12f39d7209e9a047a 970 PRINTS PR00986 Valyl-tRNA synthetase signature 511 529 2.3E-35 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CDC59_RS06050 ed9b525d9f7270a12f39d7209e9a047a 970 SUPERFAMILY SSF47323 647 915 3.36E-61 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDC59_RS06050 ed9b525d9f7270a12f39d7209e9a047a 970 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 49 60 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDC59_RS06050 ed9b525d9f7270a12f39d7209e9a047a 970 SUPERFAMILY SSF46589 901 965 1.62E-17 T 29-03-2018 IPR010978 tRNA-binding arm GO:0000166 CDC59_RS06050 ed9b525d9f7270a12f39d7209e9a047a 970 SUPERFAMILY SSF52374 8 198 2.7E-131 T 29-03-2018 CDC59_RS06050 ed9b525d9f7270a12f39d7209e9a047a 970 SUPERFAMILY SSF52374 614 646 2.7E-131 T 29-03-2018 CDC59_RS06050 ed9b525d9f7270a12f39d7209e9a047a 970 SUPERFAMILY SSF52374 362 576 2.7E-131 T 29-03-2018 CDC59_RS06050 ed9b525d9f7270a12f39d7209e9a047a 970 TIGRFAM TIGR00422 valS: valine--tRNA ligase 9 947 0.0 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CDC59_RS06050 ed9b525d9f7270a12f39d7209e9a047a 970 Gene3D G3DSA:3.40.50.620 5 624 6.7E-131 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDC59_RS06050 ed9b525d9f7270a12f39d7209e9a047a 970 Hamap MF_02004 Valine--tRNA ligase [valS]. 8 966 15.364 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CDC59_RS06050 ed9b525d9f7270a12f39d7209e9a047a 970 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 901 965 9.7E-20 T 29-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 CDC59_RS04050 25868e1b2dd824f301a905d72d9bb702 518 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 145 161 - T 29-03-2018 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 CDC59_RS04050 25868e1b2dd824f301a905d72d9bb702 518 Pfam PF00221 Aromatic amino acid lyase 18 476 3.5E-183 T 29-03-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 CDC59_RS04050 25868e1b2dd824f301a905d72d9bb702 518 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 11 509 5.1E-210 T 29-03-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CDC59_RS04050 25868e1b2dd824f301a905d72d9bb702 518 Gene3D G3DSA:1.20.200.10 205 515 1.5E-118 T 29-03-2018 CDC59_RS04050 25868e1b2dd824f301a905d72d9bb702 518 SUPERFAMILY SSF48557 4 504 8.63E-187 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 CDC59_RS04050 25868e1b2dd824f301a905d72d9bb702 518 Gene3D G3DSA:1.10.275.10 8 203 1.0E-68 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal CDC59_RS04050 25868e1b2dd824f301a905d72d9bb702 518 Hamap MF_00229 Histidine ammonia-lyase [hutH]. 9 510 46.324 T 29-03-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CDC59_RS22805 93d8f5f9de801e0599e968d1a8f6b94d 203 SUPERFAMILY SSF81452 15 186 4.45E-34 T 29-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS22805 93d8f5f9de801e0599e968d1a8f6b94d 203 Pfam PF00510 Cytochrome c oxidase subunit III 70 185 3.7E-7 T 29-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS22805 93d8f5f9de801e0599e968d1a8f6b94d 203 Gene3D G3DSA:1.20.120.80 15 189 1.4E-26 T 29-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS06020 931ea88d6c1f15f8125bf297055077c8 410 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 278 293 1.8E-29 T 29-03-2018 CDC59_RS06020 931ea88d6c1f15f8125bf297055077c8 410 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 151 166 1.8E-29 T 29-03-2018 CDC59_RS06020 931ea88d6c1f15f8125bf297055077c8 410 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 293 309 1.8E-29 T 29-03-2018 CDC59_RS06020 931ea88d6c1f15f8125bf297055077c8 410 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 1.8E-29 T 29-03-2018 CDC59_RS06020 931ea88d6c1f15f8125bf297055077c8 410 Gene3D G3DSA:3.50.50.60 1 166 6.5E-14 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS06020 931ea88d6c1f15f8125bf297055077c8 410 Gene3D G3DSA:3.30.9.10 167 284 9.2E-50 T 29-03-2018 CDC59_RS06020 931ea88d6c1f15f8125bf297055077c8 410 Gene3D G3DSA:3.30.9.10 311 388 2.4E-19 T 29-03-2018 CDC59_RS06020 931ea88d6c1f15f8125bf297055077c8 410 Pfam PF01494 FAD binding domain 2 342 3.4E-81 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 CDC59_RS06020 931ea88d6c1f15f8125bf297055077c8 410 SUPERFAMILY SSF54373 176 274 1.37E-41 T 29-03-2018 CDC59_RS06020 931ea88d6c1f15f8125bf297055077c8 410 SUPERFAMILY SSF51905 1 172 5.43E-57 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS06020 931ea88d6c1f15f8125bf297055077c8 410 SUPERFAMILY SSF51905 274 390 5.43E-57 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS06020 931ea88d6c1f15f8125bf297055077c8 410 TIGRFAM TIGR02360 pbenz_hydroxyl: 4-hydroxybenzoate 3-monooxygenase 1 390 1.6E-172 T 29-03-2018 IPR012733 4-hydroxybenzoate 3-monooxygenase GO:0018659|GO:0043639|GO:0050660|GO:0055114 CDC59_RS09490 32b2aff345f727fe6890a7129c605de9 268 SUPERFAMILY SSF56176 1 167 9.35E-48 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CDC59_RS09490 32b2aff345f727fe6890a7129c605de9 268 Gene3D G3DSA:3.30.390.50 169 268 1.0E-14 T 29-03-2018 CDC59_RS09490 32b2aff345f727fe6890a7129c605de9 268 SUPERFAMILY SSF55447 170 265 2.75E-19 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal CDC59_RS09490 32b2aff345f727fe6890a7129c605de9 268 Gene3D G3DSA:3.30.43.10 1 51 1.7E-16 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CDC59_RS09490 32b2aff345f727fe6890a7129c605de9 268 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 3 167 1.2E-45 T 29-03-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 CDC59_RS09490 32b2aff345f727fe6890a7129c605de9 268 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 180 262 5.0E-5 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal CDC59_RS09490 32b2aff345f727fe6890a7129c605de9 268 SMART SM01092 171 263 1.6E-18 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal CDC59_RS09490 32b2aff345f727fe6890a7129c605de9 268 Gene3D G3DSA:3.30.465.10 55 168 8.7E-27 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CDC59_RS22440 1c7308a30eca1597e9a460e6d51315b6 212 Gene3D G3DSA:3.40.30.10 46 210 7.6E-17 T 29-03-2018 CDC59_RS22440 1c7308a30eca1597e9a460e6d51315b6 212 Pfam PF02630 SCO1/SenC 77 142 2.0E-8 T 29-03-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS22440 1c7308a30eca1597e9a460e6d51315b6 212 SUPERFAMILY SSF52833 51 197 1.73E-20 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS03670 56b92a8877d6c45f3a39ffba3516bc62 157 SUPERFAMILY SSF46785 8 144 4.13E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS03670 56b92a8877d6c45f3a39ffba3516bc62 157 ProSitePatterns PS01117 MarR-type HTH domain signature. 69 103 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CDC59_RS03670 56b92a8877d6c45f3a39ffba3516bc62 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 120 140 1.4E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS03670 56b92a8877d6c45f3a39ffba3516bc62 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 90 106 1.4E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS03670 56b92a8877d6c45f3a39ffba3516bc62 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 54 70 1.4E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS03670 56b92a8877d6c45f3a39ffba3516bc62 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 71 86 1.4E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS03670 56b92a8877d6c45f3a39ffba3516bc62 157 Pfam PF01047 MarR family 37 94 1.2E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS03670 56b92a8877d6c45f3a39ffba3516bc62 157 Gene3D G3DSA:1.10.10.10 2 151 5.7E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS03670 56b92a8877d6c45f3a39ffba3516bc62 157 SMART SM00347 30 130 1.5E-21 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS06140 3cf76a66940b61944eed44b292e9c237 412 Pfam PF03486 HI0933-like protein 4 407 3.4E-145 T 29-03-2018 CDC59_RS06140 3cf76a66940b61944eed44b292e9c237 412 Gene3D G3DSA:2.40.30.10 196 284 4.5E-23 T 29-03-2018 CDC59_RS06140 3cf76a66940b61944eed44b292e9c237 412 Gene3D G3DSA:3.50.50.60 2 195 4.9E-20 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS06140 3cf76a66940b61944eed44b292e9c237 412 SUPERFAMILY SSF160996 189 355 3.01E-38 T 29-03-2018 CDC59_RS06140 3cf76a66940b61944eed44b292e9c237 412 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 1.7E-6 T 29-03-2018 CDC59_RS06140 3cf76a66940b61944eed44b292e9c237 412 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 155 164 1.7E-6 T 29-03-2018 CDC59_RS06140 3cf76a66940b61944eed44b292e9c237 412 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 6 407 1.2E-117 T 29-03-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like CDC59_RS06140 3cf76a66940b61944eed44b292e9c237 412 Gene3D G3DSA:1.10.8.260 285 336 3.3E-19 T 29-03-2018 IPR023166 HI0933 insert-like domain CDC59_RS06140 3cf76a66940b61944eed44b292e9c237 412 SUPERFAMILY SSF51905 1 188 6.18E-52 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS06140 3cf76a66940b61944eed44b292e9c237 412 SUPERFAMILY SSF51905 352 411 6.18E-52 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS01620 451f80895b3d83ddaec11f48da9ca010 341 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 30 135 1.2E-32 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CDC59_RS01620 451f80895b3d83ddaec11f48da9ca010 341 SUPERFAMILY SSF50129 310 338 1.16E-55 T 29-03-2018 IPR011032 GroES-like CDC59_RS01620 451f80895b3d83ddaec11f48da9ca010 341 SUPERFAMILY SSF50129 4 146 1.16E-55 T 29-03-2018 IPR011032 GroES-like CDC59_RS01620 451f80895b3d83ddaec11f48da9ca010 341 SUPERFAMILY SSF51735 143 308 2.03E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS01620 451f80895b3d83ddaec11f48da9ca010 341 Gene3D G3DSA:3.40.50.720 165 310 1.5E-27 T 29-03-2018 CDC59_RS01620 451f80895b3d83ddaec11f48da9ca010 341 Pfam PF00107 Zinc-binding dehydrogenase 179 304 5.7E-28 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CDC59_RS01620 451f80895b3d83ddaec11f48da9ca010 341 Gene3D G3DSA:3.90.180.10 5 164 4.5E-58 T 29-03-2018 CDC59_RS01620 451f80895b3d83ddaec11f48da9ca010 341 SMART SM00829 14 338 2.4E-4 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CDC59_RS01620 451f80895b3d83ddaec11f48da9ca010 341 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 64 78 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CDC59_RS12620 382ddb786c17556bd9c27bd7c7413854 216 Pfam PF00551 Formyl transferase 2 182 1.1E-59 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CDC59_RS12620 382ddb786c17556bd9c27bd7c7413854 216 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 134 157 - T 29-03-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CDC59_RS12620 382ddb786c17556bd9c27bd7c7413854 216 Gene3D G3DSA:3.40.50.170 1 201 3.1E-67 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CDC59_RS12620 382ddb786c17556bd9c27bd7c7413854 216 SUPERFAMILY SSF53328 2 193 1.96E-65 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CDC59_RS12620 382ddb786c17556bd9c27bd7c7413854 216 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 2 192 2.7E-74 T 29-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 CDC59_RS12620 382ddb786c17556bd9c27bd7c7413854 216 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 3 188 31.716 T 29-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 CDC59_RS01035 b508d05c0e69c6e2df6241ddc7a627a5 204 ProSitePatterns PS00949 Autoinducer synthase family signature. 22 48 - T 29-03-2018 IPR018311 Autoinducer synthesis, conserved site KEGG: 00270+2.3.1.184|MetaCyc: PWY-6157 CDC59_RS01035 b508d05c0e69c6e2df6241ddc7a627a5 204 Pfam PF00765 Autoinducer synthase 21 186 6.2E-23 T 29-03-2018 IPR001690 Autoinducer synthase GO:0016740 KEGG: 00270+2.3.1.184|MetaCyc: PWY-6157 CDC59_RS01035 b508d05c0e69c6e2df6241ddc7a627a5 204 SUPERFAMILY SSF55729 18 190 2.76E-38 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDC59_RS01035 b508d05c0e69c6e2df6241ddc7a627a5 204 PRINTS PR01549 Autoinducer synthesis protein signature 97 109 5.0E-18 T 29-03-2018 IPR001690 Autoinducer synthase GO:0016740 KEGG: 00270+2.3.1.184|MetaCyc: PWY-6157 CDC59_RS01035 b508d05c0e69c6e2df6241ddc7a627a5 204 PRINTS PR01549 Autoinducer synthesis protein signature 144 165 5.0E-18 T 29-03-2018 IPR001690 Autoinducer synthase GO:0016740 KEGG: 00270+2.3.1.184|MetaCyc: PWY-6157 CDC59_RS01035 b508d05c0e69c6e2df6241ddc7a627a5 204 PRINTS PR01549 Autoinducer synthesis protein signature 122 143 5.0E-18 T 29-03-2018 IPR001690 Autoinducer synthase GO:0016740 KEGG: 00270+2.3.1.184|MetaCyc: PWY-6157 CDC59_RS01035 b508d05c0e69c6e2df6241ddc7a627a5 204 PRINTS PR01549 Autoinducer synthesis protein signature 18 37 5.0E-18 T 29-03-2018 IPR001690 Autoinducer synthase GO:0016740 KEGG: 00270+2.3.1.184|MetaCyc: PWY-6157 CDC59_RS01035 b508d05c0e69c6e2df6241ddc7a627a5 204 PRINTS PR01549 Autoinducer synthesis protein signature 39 61 5.0E-18 T 29-03-2018 IPR001690 Autoinducer synthase GO:0016740 KEGG: 00270+2.3.1.184|MetaCyc: PWY-6157 CDC59_RS01035 b508d05c0e69c6e2df6241ddc7a627a5 204 PRINTS PR01549 Autoinducer synthesis protein signature 63 81 5.0E-18 T 29-03-2018 IPR001690 Autoinducer synthase GO:0016740 KEGG: 00270+2.3.1.184|MetaCyc: PWY-6157 CDC59_RS01035 b508d05c0e69c6e2df6241ddc7a627a5 204 Gene3D G3DSA:3.40.630.30 12 197 1.1E-35 T 29-03-2018 CDC59_RS13710 e6d3b608b937160c702a4926551cc142 357 PIRSF PIRSF006621 1 329 9.7E-108 T 29-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CDC59_RS13710 e6d3b608b937160c702a4926551cc142 357 Hamap MF_02042 tRNA-dihydrouridine synthase B [dusB]. 1 323 50.617 T 29-03-2018 IPR032887 tRNA-dihydrouridine synthase B GO:0002943|GO:0017150 CDC59_RS13710 e6d3b608b937160c702a4926551cc142 357 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 94 112 - T 29-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 CDC59_RS13710 e6d3b608b937160c702a4926551cc142 357 Gene3D G3DSA:3.20.20.70 8 242 1.1E-53 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS13710 e6d3b608b937160c702a4926551cc142 357 Gene3D G3DSA:1.10.1200.80 254 330 5.1E-25 T 29-03-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 CDC59_RS13710 e6d3b608b937160c702a4926551cc142 357 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 3 320 1.1E-123 T 29-03-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 CDC59_RS13710 e6d3b608b937160c702a4926551cc142 357 SUPERFAMILY SSF51395 10 321 9.52E-88 T 29-03-2018 CDC59_RS13710 e6d3b608b937160c702a4926551cc142 357 Pfam PF01207 Dihydrouridine synthase (Dus) 14 321 6.4E-106 T 29-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CDC59_RS14365 242a5fd23ea658bf3d7037e59b782578 208 SMART SM01012 148 203 2.9E-24 T 29-03-2018 IPR005561 ANTAR domain GO:0003723 CDC59_RS14365 242a5fd23ea658bf3d7037e59b782578 208 PIRSF PIRSF036382 10 208 2.6E-60 T 29-03-2018 IPR008327 Signal transduction response regulator, antiterminator CDC59_RS14365 242a5fd23ea658bf3d7037e59b782578 208 Gene3D G3DSA:3.40.50.2300 2 153 7.2E-14 T 29-03-2018 CDC59_RS14365 242a5fd23ea658bf3d7037e59b782578 208 SUPERFAMILY SSF52172 15 203 6.45E-42 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS14365 242a5fd23ea658bf3d7037e59b782578 208 Pfam PF03861 ANTAR domain 152 203 9.8E-20 T 29-03-2018 IPR005561 ANTAR domain GO:0003723 CDC59_RS14365 242a5fd23ea658bf3d7037e59b782578 208 Gene3D G3DSA:1.10.10.10 154 204 6.3E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS13900 2b6d12a3b3e8a9f8002dfc05c25bdc98 554 SMART SM00882 3 252 3.7E-52 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CDC59_RS13900 2b6d12a3b3e8a9f8002dfc05c25bdc98 554 SUPERFAMILY SSF100950 301 548 3.91E-59 T 29-03-2018 CDC59_RS13900 2b6d12a3b3e8a9f8002dfc05c25bdc98 554 SUPERFAMILY SSF100950 3 262 1.14E-70 T 29-03-2018 CDC59_RS13900 2b6d12a3b3e8a9f8002dfc05c25bdc98 554 Gene3D G3DSA:3.40.1080.10 299 553 5.2E-45 T 29-03-2018 CDC59_RS13900 2b6d12a3b3e8a9f8002dfc05c25bdc98 554 PIRSF PIRSF000858 1 554 1.1E-202 T 29-03-2018 IPR014388 3-oxoacid CoA-transferase GO:0008410|GO:0046952 Reactome: R-HSA-77108 CDC59_RS13900 2b6d12a3b3e8a9f8002dfc05c25bdc98 554 Pfam PF01144 Coenzyme A transferase 5 252 7.8E-22 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CDC59_RS13900 2b6d12a3b3e8a9f8002dfc05c25bdc98 554 Gene3D G3DSA:3.40.1080.10 2 275 9.6E-65 T 29-03-2018 CDC59_RS05345 d6ebd147b432a835f7570ab75e1bd431 386 ProDom PD332323 CIRCULATION DNA PROTEIN TAIL/DNA PHAGE PROPHAGE VIRION FLUMU BACTERIOPHAGE MU-LIKE 3 170 8.0E-20 T 29-03-2018 IPR009826 DNA circulation, N-terminal CDC59_RS05345 d6ebd147b432a835f7570ab75e1bd431 386 Pfam PF07157 DNA circularisation protein N-terminus 8 90 4.8E-25 T 29-03-2018 IPR009826 DNA circulation, N-terminal CDC59_RS23575 8487cc67f974834281494707cd10a25c 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.6E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS23575 8487cc67f974834281494707cd10a25c 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.6E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS23575 8487cc67f974834281494707cd10a25c 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.6E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS23575 8487cc67f974834281494707cd10a25c 295 Pfam PF03466 LysR substrate binding domain 88 290 9.1E-41 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS23575 8487cc67f974834281494707cd10a25c 295 Gene3D G3DSA:1.10.10.10 1 83 3.0E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS23575 8487cc67f974834281494707cd10a25c 295 Gene3D G3DSA:3.40.190.10 89 178 2.7E-24 T 29-03-2018 CDC59_RS23575 8487cc67f974834281494707cd10a25c 295 Gene3D G3DSA:3.40.190.10 179 265 1.1E-15 T 29-03-2018 CDC59_RS23575 8487cc67f974834281494707cd10a25c 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 2.7E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS23575 8487cc67f974834281494707cd10a25c 295 SUPERFAMILY SSF53850 90 293 1.18E-35 T 29-03-2018 CDC59_RS23575 8487cc67f974834281494707cd10a25c 295 SUPERFAMILY SSF46785 1 110 1.11E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS02580 ab77e8998419f1c8494cf05f432edadc 376 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 22 369 4.1E-95 T 29-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CDC59_RS02580 ab77e8998419f1c8494cf05f432edadc 376 SUPERFAMILY SSF53383 24 370 5.64E-75 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS02580 ab77e8998419f1c8494cf05f432edadc 376 Pfam PF00155 Aminotransferase class I and II 41 367 5.6E-44 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CDC59_RS02580 ab77e8998419f1c8494cf05f432edadc 376 Gene3D G3DSA:3.40.640.10 71 263 2.7E-38 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDC59_RS02580 ab77e8998419f1c8494cf05f432edadc 376 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 20 372 55.824 T 29-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CDC59_RS02580 ab77e8998419f1c8494cf05f432edadc 376 Gene3D G3DSA:3.90.1150.10 264 376 9.5E-24 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS19295 8c0ba7d81daae14ebdfd804f977b7846 294 Gene3D G3DSA:3.40.50.720 9 170 1.3E-20 T 29-03-2018 CDC59_RS19295 8c0ba7d81daae14ebdfd804f977b7846 294 SUPERFAMILY SSF51735 13 169 1.6E-31 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS19295 8c0ba7d81daae14ebdfd804f977b7846 294 Pfam PF10728 Domain of unknown function (DUF2520) 141 267 8.4E-29 T 29-03-2018 IPR018931 Domain of unknown function DUF2520 CDC59_RS19295 8c0ba7d81daae14ebdfd804f977b7846 294 Gene3D G3DSA:1.10.1040.20 172 272 4.1E-22 T 29-03-2018 IPR018931 Domain of unknown function DUF2520 CDC59_RS19295 8c0ba7d81daae14ebdfd804f977b7846 294 SUPERFAMILY SSF48179 172 275 1.6E-19 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CDC59_RS19295 8c0ba7d81daae14ebdfd804f977b7846 294 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 13 98 8.3E-12 T 29-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal CDC59_RS08755 df33e2a47045f2682c6317b06e157f5e 126 SUPERFAMILY SSF64076 10 123 2.09E-38 T 29-03-2018 IPR007523 NDUFAF3/Mth938 domain-containing protein CDC59_RS08755 df33e2a47045f2682c6317b06e157f5e 126 Pfam PF04430 Protein of unknown function (DUF498/DUF598) 16 122 9.8E-36 T 29-03-2018 IPR007523 NDUFAF3/Mth938 domain-containing protein CDC59_RS08755 df33e2a47045f2682c6317b06e157f5e 126 Gene3D G3DSA:3.40.1230.10 1 123 8.2E-38 T 29-03-2018 IPR007523 NDUFAF3/Mth938 domain-containing protein CDC59_RS03220 32a3658f6540e9008f9cc7caa742cd7c 421 ProSitePatterns PS00874 Bacterial type II secretion system protein F signature. 182 210 - T 29-03-2018 IPR001992 Type II secretion system conserved site GO:0009306|GO:0016020 CDC59_RS03220 32a3658f6540e9008f9cc7caa742cd7c 421 Pfam PF00482 Type II secretion system (T2SS), protein F 291 413 1.3E-29 T 29-03-2018 IPR018076 Type II secretion system F domain CDC59_RS03220 32a3658f6540e9008f9cc7caa742cd7c 421 Pfam PF00482 Type II secretion system (T2SS), protein F 87 210 5.8E-35 T 29-03-2018 IPR018076 Type II secretion system F domain CDC59_RS03220 32a3658f6540e9008f9cc7caa742cd7c 421 PRINTS PR00812 Bacterial general secretion pathway protein F signature 402 421 4.1E-17 T 29-03-2018 IPR003004 GspF/PilC family CDC59_RS03220 32a3658f6540e9008f9cc7caa742cd7c 421 PRINTS PR00812 Bacterial general secretion pathway protein F signature 83 95 4.1E-17 T 29-03-2018 IPR003004 GspF/PilC family CDC59_RS03220 32a3658f6540e9008f9cc7caa742cd7c 421 PRINTS PR00812 Bacterial general secretion pathway protein F signature 386 400 4.1E-17 T 29-03-2018 IPR003004 GspF/PilC family CDC59_RS03220 32a3658f6540e9008f9cc7caa742cd7c 421 PRINTS PR00812 Bacterial general secretion pathway protein F signature 182 210 4.1E-17 T 29-03-2018 IPR003004 GspF/PilC family CDC59_RS00400 8f5084401ab50aaac103962f7d0e2c43 435 Gene3D G3DSA:3.30.9.10 207 355 2.8E-22 T 29-03-2018 CDC59_RS00400 8f5084401ab50aaac103962f7d0e2c43 435 SUPERFAMILY SSF51905 356 417 1.9E-47 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS00400 8f5084401ab50aaac103962f7d0e2c43 435 SUPERFAMILY SSF51905 39 264 1.9E-47 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS00400 8f5084401ab50aaac103962f7d0e2c43 435 Gene3D G3DSA:3.50.50.60 10 129 3.2E-18 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS00400 8f5084401ab50aaac103962f7d0e2c43 435 Gene3D G3DSA:3.30.9.10 133 206 4.2E-5 T 29-03-2018 CDC59_RS00400 8f5084401ab50aaac103962f7d0e2c43 435 Pfam PF01266 FAD dependent oxidoreductase 40 393 2.4E-60 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CDC59_RS11755 5ff65b3479c7c1dd389c9202296d615b 686 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 73 130 1.2E-26 T 29-03-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS11755 5ff65b3479c7c1dd389c9202296d615b 686 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 9 680 3.0E-245 T 29-03-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS11755 5ff65b3479c7c1dd389c9202296d615b 686 Pfam PF00361 Proton-conducting membrane transporter 142 424 5.8E-87 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS11755 5ff65b3479c7c1dd389c9202296d615b 686 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 279 301 1.9E-14 T 29-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CDC59_RS11755 5ff65b3479c7c1dd389c9202296d615b 686 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 43 62 1.9E-14 T 29-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CDC59_RS11755 5ff65b3479c7c1dd389c9202296d615b 686 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 494 515 1.9E-14 T 29-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CDC59_RS11755 5ff65b3479c7c1dd389c9202296d615b 686 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 93 113 1.9E-14 T 29-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CDC59_RS11755 5ff65b3479c7c1dd389c9202296d615b 686 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 433 455 1.9E-14 T 29-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CDC59_RS11755 5ff65b3479c7c1dd389c9202296d615b 686 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 239 260 1.1E-66 T 29-03-2018 CDC59_RS11755 5ff65b3479c7c1dd389c9202296d615b 686 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 261 287 1.1E-66 T 29-03-2018 CDC59_RS11755 5ff65b3479c7c1dd389c9202296d615b 686 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 329 341 1.1E-66 T 29-03-2018 CDC59_RS11755 5ff65b3479c7c1dd389c9202296d615b 686 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 434 453 1.1E-66 T 29-03-2018 CDC59_RS11755 5ff65b3479c7c1dd389c9202296d615b 686 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 166 187 1.1E-66 T 29-03-2018 CDC59_RS11755 5ff65b3479c7c1dd389c9202296d615b 686 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 119 139 1.1E-66 T 29-03-2018 CDC59_RS11755 5ff65b3479c7c1dd389c9202296d615b 686 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 91 116 1.1E-66 T 29-03-2018 CDC59_RS19665 11d927f2e6c0cd2f3fbfa6e705d3f9cf 908 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 814 889 1.2E-9 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CDC59_RS19665 11d927f2e6c0cd2f3fbfa6e705d3f9cf 908 Gene3D G3DSA:3.40.50.300 186 371 7.9E-24 T 29-03-2018 CDC59_RS19665 11d927f2e6c0cd2f3fbfa6e705d3f9cf 908 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 232 344 1.4E-9 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CDC59_RS19665 11d927f2e6c0cd2f3fbfa6e705d3f9cf 908 Gene3D G3DSA:1.10.1780.10 2 163 6.4E-28 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CDC59_RS19665 11d927f2e6c0cd2f3fbfa6e705d3f9cf 908 Gene3D G3DSA:1.10.8.60 813 906 1.4E-9 T 29-03-2018 CDC59_RS19665 11d927f2e6c0cd2f3fbfa6e705d3f9cf 908 Gene3D G3DSA:3.40.50.300 593 811 8.2E-40 T 29-03-2018 CDC59_RS19665 11d927f2e6c0cd2f3fbfa6e705d3f9cf 908 SUPERFAMILY SSF81923 11 126 5.62E-17 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CDC59_RS19665 11d927f2e6c0cd2f3fbfa6e705d3f9cf 908 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 23 74 5.9E-9 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CDC59_RS19665 11d927f2e6c0cd2f3fbfa6e705d3f9cf 908 SUPERFAMILY SSF52540 587 883 8.11E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS19665 11d927f2e6c0cd2f3fbfa6e705d3f9cf 908 SMART SM00382 227 372 1.0E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS19665 11d927f2e6c0cd2f3fbfa6e705d3f9cf 908 SMART SM00382 638 780 1.5E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS19665 11d927f2e6c0cd2f3fbfa6e705d3f9cf 908 Pfam PF07724 AAA domain (Cdc48 subfamily) 638 806 9.1E-42 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CDC59_RS19665 11d927f2e6c0cd2f3fbfa6e705d3f9cf 908 TIGRFAM TIGR03345 VI_ClpV1: type VI secretion ATPase, ClpV1 family 12 896 0.0 T 29-03-2018 IPR017729 Type VI secretion system, ATPase ClpV1 CDC59_RS19665 11d927f2e6c0cd2f3fbfa6e705d3f9cf 908 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 323 335 - T 29-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 CDC59_RS19665 11d927f2e6c0cd2f3fbfa6e705d3f9cf 908 Gene3D G3DSA:1.10.8.60 374 588 1.9E-34 T 29-03-2018 CDC59_RS19665 11d927f2e6c0cd2f3fbfa6e705d3f9cf 908 SUPERFAMILY SSF52540 187 512 1.38E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS19665 11d927f2e6c0cd2f3fbfa6e705d3f9cf 908 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 749 763 1.3E-34 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CDC59_RS19665 11d927f2e6c0cd2f3fbfa6e705d3f9cf 908 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 642 660 1.3E-34 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CDC59_RS19665 11d927f2e6c0cd2f3fbfa6e705d3f9cf 908 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 687 705 1.3E-34 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CDC59_RS19665 11d927f2e6c0cd2f3fbfa6e705d3f9cf 908 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 716 734 1.3E-34 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CDC59_RS19665 11d927f2e6c0cd2f3fbfa6e705d3f9cf 908 SMART SM01086 812 905 3.0E-7 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CDC59_RS17835 f29c3c0b9dc6a5071981930d666f2161 524 Gene3D G3DSA:3.50.50.60 201 367 2.1E-27 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS17835 f29c3c0b9dc6a5071981930d666f2161 524 PIRSF PIRSF000238 1 521 4.3E-264 T 29-03-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0016651|GO:0050660|GO:0051287|GO:0055114 CDC59_RS17835 f29c3c0b9dc6a5071981930d666f2161 524 Pfam PF13192 Thioredoxin domain 125 193 6.3E-8 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS17835 f29c3c0b9dc6a5071981930d666f2161 524 Gene3D G3DSA:3.40.50.720 368 524 1.4E-25 T 29-03-2018 CDC59_RS17835 f29c3c0b9dc6a5071981930d666f2161 524 SUPERFAMILY SSF52833 104 197 2.06E-22 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS17835 f29c3c0b9dc6a5071981930d666f2161 524 SUPERFAMILY SSF52833 1 101 2.01E-28 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS17835 f29c3c0b9dc6a5071981930d666f2161 524 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 266 276 2.1E-63 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CDC59_RS17835 f29c3c0b9dc6a5071981930d666f2161 524 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 353 377 2.1E-63 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CDC59_RS17835 f29c3c0b9dc6a5071981930d666f2161 524 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 214 236 2.1E-63 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CDC59_RS17835 f29c3c0b9dc6a5071981930d666f2161 524 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 246 261 2.1E-63 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CDC59_RS17835 f29c3c0b9dc6a5071981930d666f2161 524 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 338 350 2.1E-63 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CDC59_RS17835 f29c3c0b9dc6a5071981930d666f2161 524 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 444 465 2.1E-63 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CDC59_RS17835 f29c3c0b9dc6a5071981930d666f2161 524 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 478 496 2.1E-63 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CDC59_RS17835 f29c3c0b9dc6a5071981930d666f2161 524 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 405 421 2.1E-63 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CDC59_RS17835 f29c3c0b9dc6a5071981930d666f2161 524 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 316 324 2.1E-63 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CDC59_RS17835 f29c3c0b9dc6a5071981930d666f2161 524 Gene3D G3DSA:3.40.30.10 1 94 3.9E-24 T 29-03-2018 CDC59_RS17835 f29c3c0b9dc6a5071981930d666f2161 524 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 442 458 2.6E-38 T 29-03-2018 CDC59_RS17835 f29c3c0b9dc6a5071981930d666f2161 524 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 357 375 2.6E-38 T 29-03-2018 CDC59_RS17835 f29c3c0b9dc6a5071981930d666f2161 524 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 315 333 2.6E-38 T 29-03-2018 CDC59_RS17835 f29c3c0b9dc6a5071981930d666f2161 524 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 215 234 2.6E-38 T 29-03-2018 CDC59_RS17835 f29c3c0b9dc6a5071981930d666f2161 524 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 468 490 2.6E-38 T 29-03-2018 CDC59_RS17835 f29c3c0b9dc6a5071981930d666f2161 524 Gene3D G3DSA:3.40.30.10 104 197 5.1E-7 T 29-03-2018 CDC59_RS17835 f29c3c0b9dc6a5071981930d666f2161 524 SUPERFAMILY SSF51905 198 514 2.12E-49 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS17835 f29c3c0b9dc6a5071981930d666f2161 524 TIGRFAM TIGR03140 AhpF: alkyl hydroperoxide reductase subunit F 1 517 2.7E-251 T 29-03-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0016651|GO:0050660|GO:0051287|GO:0055114 CDC59_RS17835 f29c3c0b9dc6a5071981930d666f2161 524 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 213 499 1.1E-40 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS17835 f29c3c0b9dc6a5071981930d666f2161 524 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 345 365 - T 29-03-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 CDC59_RS21570 39fb7edbbc0f3a4f07e6d34e7608100e 465 SUPERFAMILY SSF53756 2 461 1.93E-144 T 29-03-2018 CDC59_RS21570 39fb7edbbc0f3a4f07e6d34e7608100e 465 Gene3D G3DSA:3.40.50.2000 1 242 1.3E-62 T 29-03-2018 CDC59_RS21570 39fb7edbbc0f3a4f07e6d34e7608100e 465 Gene3D G3DSA:3.40.50.2000 243 445 2.6E-38 T 29-03-2018 CDC59_RS21570 39fb7edbbc0f3a4f07e6d34e7608100e 465 TIGRFAM TIGR02400 trehalose_OtsA: alpha,alpha-trehalose-phosphate synthase (UDP-forming) 3 460 5.0E-185 T 29-03-2018 IPR012766 Alpha,alpha-trehalose-phosphate synthase GO:0003825|GO:0005992 KEGG: 00500+2.4.1.15 CDC59_RS21570 39fb7edbbc0f3a4f07e6d34e7608100e 465 Pfam PF00982 Glycosyltransferase family 20 17 459 5.3E-130 T 29-03-2018 IPR001830 Glycosyl transferase, family 20 GO:0003824|GO:0005992 CDC59_RS17160 9a19cfe77b16fc7f9f771b9b6566d1d5 362 Gene3D G3DSA:1.25.40.10 175 271 4.2E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS17160 9a19cfe77b16fc7f9f771b9b6566d1d5 362 Gene3D G3DSA:3.90.550.10 2 174 5.3E-21 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDC59_RS17160 9a19cfe77b16fc7f9f771b9b6566d1d5 362 SUPERFAMILY SSF53448 12 154 3.54E-21 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDC59_RS17160 9a19cfe77b16fc7f9f771b9b6566d1d5 362 SUPERFAMILY SSF48452 192 295 4.13E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS17160 9a19cfe77b16fc7f9f771b9b6566d1d5 362 SUPERFAMILY SSF48452 322 347 4.13E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS17160 9a19cfe77b16fc7f9f771b9b6566d1d5 362 Gene3D G3DSA:1.25.40.10 272 350 0.024 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS17160 9a19cfe77b16fc7f9f771b9b6566d1d5 362 Pfam PF00535 Glycosyl transferase family 2 15 97 4.6E-13 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CDC59_RS00950 4f3970da71edb522c568b3aa213dfdb4 377 SUPERFAMILY SSF55931 4 369 3.27E-116 T 29-03-2018 CDC59_RS00950 4f3970da71edb522c568b3aa213dfdb4 377 TIGRFAM TIGR02050 gshA_cyan_rel: carboxylate-amine ligase, YbdK family 13 297 6.0E-115 T 29-03-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CDC59_RS00950 4f3970da71edb522c568b3aa213dfdb4 377 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 14 291 6.0E-59 T 29-03-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CDC59_RS00950 4f3970da71edb522c568b3aa213dfdb4 377 Hamap MF_01609 Glutamate--cysteine ligase [gshA]. 1 377 103.304 T 29-03-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CDC59_RS00385 2229c854eabd9c9fa73f443c5491b668 258 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 37 257 4.9E-54 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CDC59_RS00385 2229c854eabd9c9fa73f443c5491b668 258 Gene3D G3DSA:3.40.190.10 137 258 1.9E-20 T 29-03-2018 CDC59_RS00385 2229c854eabd9c9fa73f443c5491b668 258 Gene3D G3DSA:3.40.190.10 28 136 1.5E-21 T 29-03-2018 CDC59_RS00385 2229c854eabd9c9fa73f443c5491b668 258 SUPERFAMILY SSF53850 10 257 4.26E-55 T 29-03-2018 CDC59_RS00385 2229c854eabd9c9fa73f443c5491b668 258 SMART SM00062 35 258 4.2E-47 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CDC59_RS06420 2e984d69ea77eb8a2ee9bd9ff1f639ae 425 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 45 391 2.3E-110 T 29-03-2018 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 CDC59_RS06420 2e984d69ea77eb8a2ee9bd9ff1f639ae 425 Gene3D G3DSA:1.10.10.10 340 424 1.6E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS06420 2e984d69ea77eb8a2ee9bd9ff1f639ae 425 SUPERFAMILY SSF102114 40 420 2.09E-108 T 29-03-2018 CDC59_RS06420 2e984d69ea77eb8a2ee9bd9ff1f639ae 425 Pfam PF06969 HemN C-terminal domain 347 409 9.9E-10 T 29-03-2018 IPR010723 HemN, C-terminal CDC59_RS06420 2e984d69ea77eb8a2ee9bd9ff1f639ae 425 Pfam PF04055 Radical SAM superfamily 49 218 8.4E-18 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CDC59_RS06420 2e984d69ea77eb8a2ee9bd9ff1f639ae 425 Gene3D G3DSA:3.20.20.70 37 339 1.2E-43 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS06420 2e984d69ea77eb8a2ee9bd9ff1f639ae 425 SMART SM00729 44 264 7.3E-49 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CDC59_RS22740 3b8b6edb2ded23e95230ce5c682e627b 438 Gene3D G3DSA:1.10.287.130 205 274 3.2E-11 T 29-03-2018 CDC59_RS22740 3b8b6edb2ded23e95230ce5c682e627b 438 Pfam PF00512 His Kinase A (phospho-acceptor) domain 216 280 2.6E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS22740 3b8b6edb2ded23e95230ce5c682e627b 438 SMART SM00388 215 280 4.0E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS22740 3b8b6edb2ded23e95230ce5c682e627b 438 Gene3D G3DSA:1.20.5.1040 112 162 1.2E-8 T 29-03-2018 CDC59_RS22740 3b8b6edb2ded23e95230ce5c682e627b 438 Gene3D G3DSA:1.20.5.1040 2 54 2.7E-10 T 29-03-2018 CDC59_RS22740 3b8b6edb2ded23e95230ce5c682e627b 438 Pfam PF08521 Two-component sensor kinase N-terminal 16 137 9.9E-9 T 29-03-2018 IPR013727 Two-component sensor kinase, N-terminal CDC59_RS22740 3b8b6edb2ded23e95230ce5c682e627b 438 SMART SM00387 326 436 1.1E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS22740 3b8b6edb2ded23e95230ce5c682e627b 438 Gene3D G3DSA:3.30.565.10 275 436 5.0E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS22740 3b8b6edb2ded23e95230ce5c682e627b 438 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 327 434 1.0E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS22740 3b8b6edb2ded23e95230ce5c682e627b 438 SUPERFAMILY SSF47384 198 280 1.31E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS22740 3b8b6edb2ded23e95230ce5c682e627b 438 SUPERFAMILY SSF55874 270 434 1.96E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS22740 3b8b6edb2ded23e95230ce5c682e627b 438 PRINTS PR00344 Bacterial sensor protein C-terminal signature 396 414 7.5E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS22740 3b8b6edb2ded23e95230ce5c682e627b 438 PRINTS PR00344 Bacterial sensor protein C-terminal signature 382 392 7.5E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS22740 3b8b6edb2ded23e95230ce5c682e627b 438 PRINTS PR00344 Bacterial sensor protein C-terminal signature 364 378 7.5E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS22740 3b8b6edb2ded23e95230ce5c682e627b 438 PRINTS PR00344 Bacterial sensor protein C-terminal signature 420 433 7.5E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS12585 eee1e01557f3287ecd73eb16d5b4e0b2 295 SUPERFAMILY SSF54675 23 127 1.88E-29 T 29-03-2018 CDC59_RS12585 eee1e01557f3287ecd73eb16d5b4e0b2 295 Gene3D G3DSA:3.20.20.70 154 283 1.1E-36 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS12585 eee1e01557f3287ecd73eb16d5b4e0b2 295 PIRSF PIRSF006250 20 295 9.8E-86 T 29-03-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 CDC59_RS12585 eee1e01557f3287ecd73eb16d5b4e0b2 295 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 38 126 2.2E-22 T 29-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 CDC59_RS12585 eee1e01557f3287ecd73eb16d5b4e0b2 295 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 128 291 4.3E-52 T 29-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CDC59_RS12585 eee1e01557f3287ecd73eb16d5b4e0b2 295 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 30 293 8.9E-84 T 29-03-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 CDC59_RS12585 eee1e01557f3287ecd73eb16d5b4e0b2 295 SUPERFAMILY SSF51690 128 293 7.46E-54 T 29-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CDC59_RS12585 eee1e01557f3287ecd73eb16d5b4e0b2 295 Gene3D G3DSA:3.90.1170.20 12 153 3.5E-42 T 29-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 CDC59_RS01205 a3bb8a442edac47b9ceb5d2307a898e2 217 SUPERFAMILY SSF46626 10 23 3.1E-13 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS01205 a3bb8a442edac47b9ceb5d2307a898e2 217 SUPERFAMILY SSF46626 102 208 3.1E-13 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS01205 a3bb8a442edac47b9ceb5d2307a898e2 217 Gene3D G3DSA:1.10.760.10 12 209 3.1E-10 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS01205 a3bb8a442edac47b9ceb5d2307a898e2 217 PIRSF PIRSF024608 5 217 2.4E-93 T 29-03-2018 IPR016823 Sulfur oxidation c-type cytochrome SoxX, type II CDC59_RS01205 a3bb8a442edac47b9ceb5d2307a898e2 217 TIGRFAM TIGR04485 thiosulf_SoxX: sulfur oxidation c-type cytochrome SoxX 131 210 7.3E-27 T 29-03-2018 IPR030999 Sulfur oxidation c-type cytochrome SoxX CDC59_RS01205 a3bb8a442edac47b9ceb5d2307a898e2 217 Pfam PF00034 Cytochrome c 131 208 3.6E-4 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS11010 5cc85b391b229f3832bd13a05f02e14e 92 Gene3D G3DSA:3.30.160.140 4 81 9.4E-18 T 29-03-2018 IPR009962 Protein of unknown function DUF1488 CDC59_RS11010 5cc85b391b229f3832bd13a05f02e14e 92 Pfam PF07369 Protein of unknown function (DUF1488) 4 82 5.3E-22 T 29-03-2018 IPR009962 Protein of unknown function DUF1488 CDC59_RS11010 5cc85b391b229f3832bd13a05f02e14e 92 SUPERFAMILY SSF160272 3 90 8.37E-15 T 29-03-2018 IPR009962 Protein of unknown function DUF1488 CDC59_RS13890 cccc64fe254bf3f0913b9719550e5cdc 595 Gene3D G3DSA:1.20.140.10 270 471 5.2E-45 T 29-03-2018 CDC59_RS13890 cccc64fe254bf3f0913b9719550e5cdc 595 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 41 158 6.6E-13 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CDC59_RS13890 cccc64fe254bf3f0913b9719550e5cdc 595 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 3 35 4.1E-14 T 29-03-2018 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria CDC59_RS13890 cccc64fe254bf3f0913b9719550e5cdc 595 SUPERFAMILY SSF56645 37 293 4.32E-60 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CDC59_RS13890 cccc64fe254bf3f0913b9719550e5cdc 595 Gene3D G3DSA:2.40.110.10 160 269 1.5E-23 T 29-03-2018 CDC59_RS13890 cccc64fe254bf3f0913b9719550e5cdc 595 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 283 452 7.4E-21 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CDC59_RS13890 cccc64fe254bf3f0913b9719550e5cdc 595 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 164 272 2.1E-17 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CDC59_RS13890 cccc64fe254bf3f0913b9719550e5cdc 595 SUPERFAMILY SSF47203 288 473 1.5E-52 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CDC59_RS13890 cccc64fe254bf3f0913b9719550e5cdc 595 Gene3D G3DSA:1.10.540.10 25 159 1.8E-19 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CDC59_RS13890 cccc64fe254bf3f0913b9719550e5cdc 595 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 472 590 1.7E-33 T 29-03-2018 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain CDC59_RS22495 98a874a58fd725172b9e4ee551018a67 186 PIRSF PIRSF006707 1 176 6.0E-56 T 29-03-2018 IPR026282 DNA-binding protein, MJ1563 type CDC59_RS22495 98a874a58fd725172b9e4ee551018a67 186 SUPERFAMILY SSF46785 2 151 2.43E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS22495 98a874a58fd725172b9e4ee551018a67 186 Pfam PF12802 MarR family 26 81 2.5E-8 T 29-03-2018 CDC59_RS22495 98a874a58fd725172b9e4ee551018a67 186 Gene3D G3DSA:1.10.10.10 1 175 4.0E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS08770 cf3be7e75b87e4fcdf76d83071cbc4f2 481 SUPERFAMILY SSF53686 1 479 5.12E-150 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CDC59_RS08770 cf3be7e75b87e4fcdf76d83071cbc4f2 481 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 97 342 6.6E-12 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CDC59_RS08770 cf3be7e75b87e4fcdf76d83071cbc4f2 481 Gene3D G3DSA:3.90.1380.10 1 89 1.5E-31 T 29-03-2018 IPR029144 Threonine synthase, N-terminal CDC59_RS08770 cf3be7e75b87e4fcdf76d83071cbc4f2 481 Pfam PF14821 Threonine synthase N terminus 2 79 2.2E-29 T 29-03-2018 IPR029144 Threonine synthase, N-terminal CDC59_RS08770 cf3be7e75b87e4fcdf76d83071cbc4f2 481 TIGRFAM TIGR00260 thrC: threonine synthase 108 440 1.7E-67 T 29-03-2018 IPR004450 Threonine synthase-like CDC59_RS08770 cf3be7e75b87e4fcdf76d83071cbc4f2 481 Gene3D G3DSA:3.40.50.1100 218 447 1.7E-82 T 29-03-2018 CDC59_RS08770 cf3be7e75b87e4fcdf76d83071cbc4f2 481 Gene3D G3DSA:3.40.50.1100 118 217 3.5E-12 T 29-03-2018 CDC59_RS06775 24b227ac3b2d3cbdfe21745965fda00f 208 SUPERFAMILY SSF158710 43 187 1.28E-50 T 29-03-2018 IPR023153 PSPTO4464-like domain CDC59_RS06775 24b227ac3b2d3cbdfe21745965fda00f 208 PIRSF PIRSF016183 16 193 7.3E-68 T 29-03-2018 IPR006839 Ribosome-associated, YjgA CDC59_RS06775 24b227ac3b2d3cbdfe21745965fda00f 208 Pfam PF04751 Protein of unknown function (DUF615) 32 185 1.5E-56 T 29-03-2018 IPR006839 Ribosome-associated, YjgA CDC59_RS06775 24b227ac3b2d3cbdfe21745965fda00f 208 Gene3D G3DSA:1.10.60.30 121 194 2.5E-28 T 29-03-2018 CDC59_RS06775 24b227ac3b2d3cbdfe21745965fda00f 208 Gene3D G3DSA:1.10.60.30 44 114 3.0E-26 T 29-03-2018 CDC59_RS06775 24b227ac3b2d3cbdfe21745965fda00f 208 Hamap MF_00765 UPF0307 protein YjgA [yjgA]. 22 189 23.1 T 29-03-2018 IPR006839 Ribosome-associated, YjgA CDC59_RS15810 563cdf778063231686dd1b542203ab0c 563 Gene3D G3DSA:3.40.50.980 15 221 2.2E-41 T 29-03-2018 CDC59_RS15810 563cdf778063231686dd1b542203ab0c 563 Pfam PF13193 AMP-binding enzyme C-terminal domain 475 549 4.0E-18 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CDC59_RS15810 563cdf778063231686dd1b542203ab0c 563 Gene3D G3DSA:3.40.50.980 222 382 5.6E-40 T 29-03-2018 CDC59_RS15810 563cdf778063231686dd1b542203ab0c 563 Gene3D G3DSA:2.30.38.10 383 459 6.8E-25 T 29-03-2018 CDC59_RS15810 563cdf778063231686dd1b542203ab0c 563 Gene3D G3DSA:3.30.300.30 460 563 2.0E-27 T 29-03-2018 CDC59_RS15810 563cdf778063231686dd1b542203ab0c 563 Pfam PF00501 AMP-binding enzyme 24 466 1.3E-94 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CDC59_RS15810 563cdf778063231686dd1b542203ab0c 563 SUPERFAMILY SSF56801 16 561 1.7E-144 T 29-03-2018 CDC59_RS15810 563cdf778063231686dd1b542203ab0c 563 ProSitePatterns PS00455 Putative AMP-binding domain signature. 215 226 - T 29-03-2018 IPR020845 AMP-binding, conserved site CDC59_RS11440 9da1a2ee66eabe0d2f039e613b2b88d4 356 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 3 352 5.2E-130 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CDC59_RS11440 9da1a2ee66eabe0d2f039e613b2b88d4 356 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 2 356 50.309 T 29-03-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 CDC59_RS11440 9da1a2ee66eabe0d2f039e613b2b88d4 356 Gene3D G3DSA:3.40.718.10 1 356 4.4E-123 T 29-03-2018 CDC59_RS11440 9da1a2ee66eabe0d2f039e613b2b88d4 356 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 243 262 - T 29-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 CDC59_RS11440 9da1a2ee66eabe0d2f039e613b2b88d4 356 SUPERFAMILY SSF53659 2 356 2.88E-120 T 29-03-2018 CDC59_RS11440 9da1a2ee66eabe0d2f039e613b2b88d4 356 SMART SM01329 3 352 3.6E-203 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CDC59_RS11440 9da1a2ee66eabe0d2f039e613b2b88d4 356 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 3 351 1.7E-146 T 29-03-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 CDC59_RS07905 bbcd6407a97e33d62139bd55933529af 416 SUPERFAMILY SSF53633 4 250 4.58E-74 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CDC59_RS07905 bbcd6407a97e33d62139bd55933529af 416 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 1 413 8.2E-124 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CDC59_RS07905 bbcd6407a97e33d62139bd55933529af 416 Gene3D G3DSA:3.30.70.260 247 338 9.2E-23 T 29-03-2018 CDC59_RS07905 bbcd6407a97e33d62139bd55933529af 416 Pfam PF13840 ACT domain 349 409 1.8E-17 T 29-03-2018 IPR027795 GATS-like ACT domain CDC59_RS07905 bbcd6407a97e33d62139bd55933529af 416 SUPERFAMILY SSF55021 257 335 8.51E-18 T 29-03-2018 CDC59_RS07905 bbcd6407a97e33d62139bd55933529af 416 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 29-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CDC59_RS07905 bbcd6407a97e33d62139bd55933529af 416 Pfam PF01842 ACT domain 276 328 1.5E-8 T 29-03-2018 IPR002912 ACT domain CDC59_RS07905 bbcd6407a97e33d62139bd55933529af 416 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 57 412 1.2E-112 T 29-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CDC59_RS07905 bbcd6407a97e33d62139bd55933529af 416 SUPERFAMILY SSF55021 340 414 1.75E-25 T 29-03-2018 CDC59_RS07905 bbcd6407a97e33d62139bd55933529af 416 Pfam PF00696 Amino acid kinase family 3 229 2.3E-49 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CDC59_RS07905 bbcd6407a97e33d62139bd55933529af 416 Gene3D G3DSA:3.30.70.260 339 412 3.5E-23 T 29-03-2018 CDC59_RS07905 bbcd6407a97e33d62139bd55933529af 416 PIRSF PIRSF000726 1 62 3.0E-21 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CDC59_RS07905 bbcd6407a97e33d62139bd55933529af 416 PIRSF PIRSF000726 56 416 5.7E-138 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CDC59_RS07905 bbcd6407a97e33d62139bd55933529af 416 Gene3D G3DSA:3.40.1160.10 1 246 3.4E-73 T 29-03-2018 CDC59_RS07310 fe380ee754b772402fd20f7f7802d2b2 249 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 10 247 1.0E-103 T 29-03-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CDC59_RS07310 fe380ee754b772402fd20f7f7802d2b2 249 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 187 2.4E-6 T 29-03-2018 CDC59_RS07310 fe380ee754b772402fd20f7f7802d2b2 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 246 7.1E-70 T 29-03-2018 CDC59_RS07310 fe380ee754b772402fd20f7f7802d2b2 249 Gene3D G3DSA:3.40.50.720 52 249 1.7E-66 T 29-03-2018 CDC59_RS07310 fe380ee754b772402fd20f7f7802d2b2 249 Gene3D G3DSA:3.40.50.720 1 51 3.4E-11 T 29-03-2018 CDC59_RS07310 fe380ee754b772402fd20f7f7802d2b2 249 SUPERFAMILY SSF51735 7 248 1.44E-87 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS07310 fe380ee754b772402fd20f7f7802d2b2 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.9E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS07310 fe380ee754b772402fd20f7f7802d2b2 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 1.9E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS07310 fe380ee754b772402fd20f7f7802d2b2 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 1.9E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS07310 fe380ee754b772402fd20f7f7802d2b2 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 5.6E-51 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS07310 fe380ee754b772402fd20f7f7802d2b2 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 5.6E-51 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS07310 fe380ee754b772402fd20f7f7802d2b2 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 5.6E-51 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS07310 fe380ee754b772402fd20f7f7802d2b2 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 5.6E-51 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS07310 fe380ee754b772402fd20f7f7802d2b2 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 5.6E-51 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS07310 fe380ee754b772402fd20f7f7802d2b2 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 5.6E-51 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS07310 fe380ee754b772402fd20f7f7802d2b2 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CDC59_RS05645 344d8850651c2687ff3dce5827a35fca 196 Gene3D G3DSA:1.20.5.40 106 124 1.9E-18 T 29-03-2018 CDC59_RS05645 344d8850651c2687ff3dce5827a35fca 196 ProSitePatterns PS00397 Site-specific recombinases active site. 5 13 - T 29-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 CDC59_RS05645 344d8850651c2687ff3dce5827a35fca 196 ProSitePatterns PS00398 Site-specific recombinases signature 2. 56 68 - T 29-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 CDC59_RS05645 344d8850651c2687ff3dce5827a35fca 196 SMART SM00857 2 137 1.7E-57 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CDC59_RS05645 344d8850651c2687ff3dce5827a35fca 196 Gene3D G3DSA:1.10.10.60 125 185 1.6E-6 T 29-03-2018 CDC59_RS05645 344d8850651c2687ff3dce5827a35fca 196 SUPERFAMILY SSF53041 1 136 5.23E-43 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CDC59_RS05645 344d8850651c2687ff3dce5827a35fca 196 Pfam PF00239 Resolvase, N terminal domain 3 136 6.9E-45 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CDC59_RS05645 344d8850651c2687ff3dce5827a35fca 196 Gene3D G3DSA:3.40.50.1390 1 105 8.4E-32 T 29-03-2018 CDC59_RS22525 b3402595341f172f9271b40244d0392f 278 SUPERFAMILY SSF46689 63 112 6.27E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS22525 b3402595341f172f9271b40244d0392f 278 Gene3D G3DSA:1.10.10.60 67 124 9.3E-12 T 29-03-2018 CDC59_RS22525 b3402595341f172f9271b40244d0392f 278 SMART SM00871 126 276 2.1E-20 T 29-03-2018 IPR010499 Bacterial transcription activator, effector binding CDC59_RS22525 b3402595341f172f9271b40244d0392f 278 Pfam PF06445 GyrI-like small molecule binding domain 128 276 6.4E-26 T 29-03-2018 IPR029442 GyrI-like small molecule binding domain CDC59_RS22525 b3402595341f172f9271b40244d0392f 278 Gene3D G3DSA:3.20.80.10 125 278 2.0E-25 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain CDC59_RS22525 b3402595341f172f9271b40244d0392f 278 Gene3D G3DSA:1.10.10.60 9 66 4.6E-12 T 29-03-2018 CDC59_RS22525 b3402595341f172f9271b40244d0392f 278 SUPERFAMILY SSF55136 127 277 4.84E-25 T 29-03-2018 CDC59_RS22525 b3402595341f172f9271b40244d0392f 278 SUPERFAMILY SSF46689 11 58 5.11E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS22525 b3402595341f172f9271b40244d0392f 278 Pfam PF12833 Helix-turn-helix domain 33 112 3.8E-20 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CDC59_RS22525 b3402595341f172f9271b40244d0392f 278 SMART SM00342 27 110 3.8E-23 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CDC59_RS10130 f3d92801b44a790f359cf857ebefe6ad 539 SUPERFAMILY SSF53697 3 537 4.45E-197 T 29-03-2018 CDC59_RS10130 f3d92801b44a790f359cf857ebefe6ad 539 Gene3D G3DSA:3.40.50.10490 1 140 4.7E-39 T 29-03-2018 CDC59_RS10130 f3d92801b44a790f359cf857ebefe6ad 539 Gene3D G3DSA:3.40.50.10490 257 503 4.1E-109 T 29-03-2018 CDC59_RS10130 f3d92801b44a790f359cf857ebefe6ad 539 Gene3D G3DSA:3.40.50.10490 141 256 6.4E-49 T 29-03-2018 CDC59_RS10130 f3d92801b44a790f359cf857ebefe6ad 539 Gene3D G3DSA:1.10.1390.10 504 539 3.3E-19 T 29-03-2018 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDC59_RS10130 f3d92801b44a790f359cf857ebefe6ad 539 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 263 276 - T 29-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDC59_RS10130 f3d92801b44a790f359cf857ebefe6ad 539 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 488 505 - T 29-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDC59_RS10130 f3d92801b44a790f359cf857ebefe6ad 539 Pfam PF00342 Phosphoglucose isomerase 49 532 5.1E-200 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDC59_RS10130 f3d92801b44a790f359cf857ebefe6ad 539 PRINTS PR00662 Glucose-6-phosphate isomerase signature 336 357 2.6E-49 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDC59_RS10130 f3d92801b44a790f359cf857ebefe6ad 539 PRINTS PR00662 Glucose-6-phosphate isomerase signature 456 474 2.6E-49 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDC59_RS10130 f3d92801b44a790f359cf857ebefe6ad 539 PRINTS PR00662 Glucose-6-phosphate isomerase signature 147 166 2.6E-49 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDC59_RS10130 f3d92801b44a790f359cf857ebefe6ad 539 PRINTS PR00662 Glucose-6-phosphate isomerase signature 488 501 2.6E-49 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDC59_RS10130 f3d92801b44a790f359cf857ebefe6ad 539 PRINTS PR00662 Glucose-6-phosphate isomerase signature 474 488 2.6E-49 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDC59_RS10130 f3d92801b44a790f359cf857ebefe6ad 539 PRINTS PR00662 Glucose-6-phosphate isomerase signature 259 277 2.6E-49 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDC59_RS10130 f3d92801b44a790f359cf857ebefe6ad 539 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 43 515 38.867 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDC59_RS20910 b717859b5b1f2efc4e2dc8b992f717b8 719 Pfam PF00593 TonB dependent receptor 295 717 5.5E-46 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CDC59_RS20910 b717859b5b1f2efc4e2dc8b992f717b8 719 Gene3D G3DSA:2.40.170.20 186 718 1.9E-57 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CDC59_RS20910 b717859b5b1f2efc4e2dc8b992f717b8 719 Gene3D G3DSA:2.170.130.10 51 183 3.0E-22 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CDC59_RS20910 b717859b5b1f2efc4e2dc8b992f717b8 719 Pfam PF07715 TonB-dependent Receptor Plug Domain 75 178 1.9E-13 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CDC59_RS20910 b717859b5b1f2efc4e2dc8b992f717b8 719 SUPERFAMILY SSF56935 55 719 1.65E-93 T 29-03-2018 CDC59_RS17330 e38fdcfdbcfc422121c5525c11f9e189 338 SUPERFAMILY SSF53686 2 312 3.67E-82 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CDC59_RS17330 e38fdcfdbcfc422121c5525c11f9e189 338 TIGRFAM TIGR03945 PLP_SbnA_fam: 2,3-diaminopropionate biosynthesis protein SbnA 7 310 7.1E-133 T 29-03-2018 IPR023927 2,3-diaminopropionate biosynthesis protein SbnA CDC59_RS17330 e38fdcfdbcfc422121c5525c11f9e189 338 Gene3D G3DSA:3.40.50.1100 21 138 1.2E-27 T 29-03-2018 CDC59_RS17330 e38fdcfdbcfc422121c5525c11f9e189 338 Gene3D G3DSA:3.40.50.1100 139 316 7.9E-42 T 29-03-2018 CDC59_RS17330 e38fdcfdbcfc422121c5525c11f9e189 338 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 32 50 - T 29-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 CDC59_RS17330 e38fdcfdbcfc422121c5525c11f9e189 338 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 294 2.2E-60 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CDC59_RS03325 612269f72349e5bd56c5440dd9c2bcbc 200 SMART SM00644 24 172 2.7E-56 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CDC59_RS03325 612269f72349e5bd56c5440dd9c2bcbc 200 Gene3D G3DSA:3.40.80.10 9 185 9.4E-53 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CDC59_RS03325 612269f72349e5bd56c5440dd9c2bcbc 200 SUPERFAMILY SSF55846 11 181 9.95E-65 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CDC59_RS03325 612269f72349e5bd56c5440dd9c2bcbc 200 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 34 173 1.8E-29 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CDC59_RS01050 86041a45e53cd49dc903555729e4d771 495 SUPERFAMILY SSF51621 157 339 2.66E-95 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CDC59_RS01050 86041a45e53cd49dc903555729e4d771 495 SUPERFAMILY SSF51621 2 77 2.66E-95 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CDC59_RS01050 86041a45e53cd49dc903555729e4d771 495 Gene3D G3DSA:3.40.1380.20 319 471 1.0E-41 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CDC59_RS01050 86041a45e53cd49dc903555729e4d771 495 SUPERFAMILY SSF50800 73 167 2.62E-24 T 29-03-2018 IPR011037 Pyruvate kinase-like, insert domain CDC59_RS01050 86041a45e53cd49dc903555729e4d771 495 Pfam PF00224 Pyruvate kinase, barrel domain 5 334 1.4E-110 T 29-03-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CDC59_RS01050 86041a45e53cd49dc903555729e4d771 495 Pfam PF02887 Pyruvate kinase, alpha/beta domain 355 467 1.2E-26 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CDC59_RS01050 86041a45e53cd49dc903555729e4d771 495 Gene3D G3DSA:3.20.20.60 5 166 7.0E-34 T 29-03-2018 CDC59_RS01050 86041a45e53cd49dc903555729e4d771 495 Gene3D G3DSA:3.20.20.60 167 318 1.7E-59 T 29-03-2018 CDC59_RS01050 86041a45e53cd49dc903555729e4d771 495 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 5 469 5.1E-146 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CDC59_RS01050 86041a45e53cd49dc903555729e4d771 495 PRINTS PR01050 Pyruvate kinase family signature 241 265 4.0E-60 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CDC59_RS01050 86041a45e53cd49dc903555729e4d771 495 PRINTS PR01050 Pyruvate kinase family signature 266 290 4.0E-60 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CDC59_RS01050 86041a45e53cd49dc903555729e4d771 495 PRINTS PR01050 Pyruvate kinase family signature 62 78 4.0E-60 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CDC59_RS01050 86041a45e53cd49dc903555729e4d771 495 PRINTS PR01050 Pyruvate kinase family signature 214 240 4.0E-60 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CDC59_RS01050 86041a45e53cd49dc903555729e4d771 495 PRINTS PR01050 Pyruvate kinase family signature 291 309 4.0E-60 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CDC59_RS01050 86041a45e53cd49dc903555729e4d771 495 PRINTS PR01050 Pyruvate kinase family signature 310 326 4.0E-60 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CDC59_RS01050 86041a45e53cd49dc903555729e4d771 495 PRINTS PR01050 Pyruvate kinase family signature 187 201 4.0E-60 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CDC59_RS01050 86041a45e53cd49dc903555729e4d771 495 SUPERFAMILY SSF52935 321 469 6.8E-34 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CDC59_RS07840 a2590d5d52a4946324087efb20bca044 240 Gene3D G3DSA:3.40.50.880 1 235 1.0E-33 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CDC59_RS07840 a2590d5d52a4946324087efb20bca044 240 Pfam PF00117 Glutamine amidotransferase class-I 43 184 4.5E-12 T 29-03-2018 IPR017926 Glutamine amidotransferase CDC59_RS07840 a2590d5d52a4946324087efb20bca044 240 SUPERFAMILY SSF52317 34 231 5.03E-40 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CDC59_RS03780 564c0dd6f4b81bd6722bdbc8322b4e6e 153 ProSitePatterns PS00519 AsnC-type HTH domain signature. 21 47 - T 29-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site CDC59_RS03780 564c0dd6f4b81bd6722bdbc8322b4e6e 153 Gene3D G3DSA:1.10.10.10 1 51 4.3E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS03780 564c0dd6f4b81bd6722bdbc8322b4e6e 153 Pfam PF13412 Winged helix-turn-helix DNA-binding 3 50 4.2E-18 T 29-03-2018 CDC59_RS03780 564c0dd6f4b81bd6722bdbc8322b4e6e 153 SUPERFAMILY SSF54909 64 147 1.05E-15 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CDC59_RS03780 564c0dd6f4b81bd6722bdbc8322b4e6e 153 Pfam PF01037 Lrp/AsnC ligand binding domain 69 142 2.0E-15 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CDC59_RS03780 564c0dd6f4b81bd6722bdbc8322b4e6e 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 4.5E-11 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CDC59_RS03780 564c0dd6f4b81bd6722bdbc8322b4e6e 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 4.5E-11 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CDC59_RS03780 564c0dd6f4b81bd6722bdbc8322b4e6e 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 4.5E-11 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CDC59_RS03780 564c0dd6f4b81bd6722bdbc8322b4e6e 153 SUPERFAMILY SSF46785 2 82 1.42E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS03780 564c0dd6f4b81bd6722bdbc8322b4e6e 153 SMART SM00344 3 112 1.8E-36 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CDC59_RS03780 564c0dd6f4b81bd6722bdbc8322b4e6e 153 Gene3D G3DSA:3.30.70.920 55 149 1.0E-20 T 29-03-2018 CDC59_RS17970 995964e17d50a281599d2d857be29747 258 SUPERFAMILY SSF51735 6 254 6.92E-76 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS17970 995964e17d50a281599d2d857be29747 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 3.1E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS17970 995964e17d50a281599d2d857be29747 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 3.1E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS17970 995964e17d50a281599d2d857be29747 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 3.1E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS17970 995964e17d50a281599d2d857be29747 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 3.1E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS17970 995964e17d50a281599d2d857be29747 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 3.1E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS17970 995964e17d50a281599d2d857be29747 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 3.1E-44 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS17970 995964e17d50a281599d2d857be29747 258 Gene3D G3DSA:3.40.50.720 44 258 6.3E-57 T 29-03-2018 CDC59_RS17970 995964e17d50a281599d2d857be29747 258 Gene3D G3DSA:3.40.50.720 1 43 1.4E-9 T 29-03-2018 CDC59_RS17970 995964e17d50a281599d2d857be29747 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 252 3.6E-57 T 29-03-2018 CDC59_RS17970 995964e17d50a281599d2d857be29747 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 4.2E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS17970 995964e17d50a281599d2d857be29747 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 4.2E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS17970 995964e17d50a281599d2d857be29747 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 4.2E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS19150 6a83d0a23dc6bad0e70a98d91a329bd4 292 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 52 270 6.4E-35 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CDC59_RS19150 6a83d0a23dc6bad0e70a98d91a329bd4 292 SMART SM00062 51 275 7.3E-33 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CDC59_RS19150 6a83d0a23dc6bad0e70a98d91a329bd4 292 Gene3D G3DSA:3.40.190.10 150 273 7.2E-18 T 29-03-2018 CDC59_RS19150 6a83d0a23dc6bad0e70a98d91a329bd4 292 Gene3D G3DSA:3.40.190.10 41 149 5.0E-22 T 29-03-2018 CDC59_RS19150 6a83d0a23dc6bad0e70a98d91a329bd4 292 SUPERFAMILY SSF53850 48 272 8.1E-45 T 29-03-2018 CDC59_RS05235 190c25b60df5919e9a6584394aabb5b4 315 SUPERFAMILY SSF47413 14 64 3.26E-6 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDC59_RS05235 190c25b60df5919e9a6584394aabb5b4 315 Pfam PF01381 Helix-turn-helix 26 63 3.7E-5 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDC59_RS05235 190c25b60df5919e9a6584394aabb5b4 315 SUPERFAMILY SSF52540 103 279 1.21E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS05235 190c25b60df5919e9a6584394aabb5b4 315 Gene3D G3DSA:3.40.50.300 61 233 1.4E-8 T 29-03-2018 CDC59_RS05235 190c25b60df5919e9a6584394aabb5b4 315 Gene3D G3DSA:1.10.260.40 18 60 1.5E-5 T 29-03-2018 CDC59_RS05235 190c25b60df5919e9a6584394aabb5b4 315 Pfam PF13401 AAA domain 101 217 2.7E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS06385 e72d55c3789d03801f90cd9fa134c9dc 247 Gene3D G3DSA:3.20.20.370 3 245 2.8E-97 T 29-03-2018 CDC59_RS06385 e72d55c3789d03801f90cd9fa134c9dc 247 SUPERFAMILY SSF88713 3 244 1.04E-91 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CDC59_RS06385 e72d55c3789d03801f90cd9fa134c9dc 247 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 2 241 43.82 T 29-03-2018 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF CDC59_RS06385 e72d55c3789d03801f90cd9fa134c9dc 247 Pfam PF03746 LamB/YcsF family 4 236 3.1E-93 T 29-03-2018 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF CDC59_RS07105 7d5bad389eef8cd0abf353b0782fc3e2 696 Gene3D G3DSA:3.40.50.300 30 431 8.5E-30 T 29-03-2018 CDC59_RS07105 7d5bad389eef8cd0abf353b0782fc3e2 696 Pfam PF02151 UvrB/uvrC motif 648 682 8.8E-10 T 29-03-2018 IPR001943 UVR domain GO:0005515 CDC59_RS07105 7d5bad389eef8cd0abf353b0782fc3e2 696 SMART SM00490 479 565 1.1E-19 T 29-03-2018 IPR001650 Helicase, C-terminal CDC59_RS07105 7d5bad389eef8cd0abf353b0782fc3e2 696 SMART SM00487 28 444 1.0E-28 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CDC59_RS07105 7d5bad389eef8cd0abf353b0782fc3e2 696 SUPERFAMILY SSF52540 23 434 5.68E-134 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS07105 7d5bad389eef8cd0abf353b0782fc3e2 696 SUPERFAMILY SSF46600 637 683 2.88E-12 T 29-03-2018 IPR001943 UVR domain GO:0005515 CDC59_RS07105 7d5bad389eef8cd0abf353b0782fc3e2 696 Pfam PF04851 Type III restriction enzyme, res subunit 36 157 3.0E-8 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CDC59_RS07105 7d5bad389eef8cd0abf353b0782fc3e2 696 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 24 680 0.0 T 29-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 CDC59_RS07105 7d5bad389eef8cd0abf353b0782fc3e2 696 Pfam PF00271 Helicase conserved C-terminal domain 455 563 1.7E-18 T 29-03-2018 IPR001650 Helicase, C-terminal CDC59_RS07105 7d5bad389eef8cd0abf353b0782fc3e2 696 SUPERFAMILY SSF52540 478 602 8.95E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS07105 7d5bad389eef8cd0abf353b0782fc3e2 696 SUPERFAMILY SSF52540 56 101 8.95E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS07105 7d5bad389eef8cd0abf353b0782fc3e2 696 Gene3D G3DSA:3.40.50.300 434 608 3.5E-33 T 29-03-2018 CDC59_RS07105 7d5bad389eef8cd0abf353b0782fc3e2 696 Gene3D G3DSA:4.10.860.10 625 687 4.2E-16 T 29-03-2018 IPR001943 UVR domain GO:0005515 CDC59_RS07105 7d5bad389eef8cd0abf353b0782fc3e2 696 Pfam PF12344 Ultra-violet resistance protein B 571 613 6.1E-22 T 29-03-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain CDC59_RS07105 7d5bad389eef8cd0abf353b0782fc3e2 696 Hamap MF_00204 UvrABC system protein B [uvrB]. 22 682 43.435 T 29-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 CDC59_RS03065 38130324c2ab84b52318852d75ae6842 569 Gene3D G3DSA:3.30.300.30 465 569 3.6E-26 T 29-03-2018 CDC59_RS03065 38130324c2ab84b52318852d75ae6842 569 Gene3D G3DSA:2.30.38.10 382 464 2.0E-26 T 29-03-2018 CDC59_RS03065 38130324c2ab84b52318852d75ae6842 569 Pfam PF00501 AMP-binding enzyme 30 471 1.4E-104 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CDC59_RS03065 38130324c2ab84b52318852d75ae6842 569 Pfam PF13193 AMP-binding enzyme C-terminal domain 480 554 4.4E-17 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CDC59_RS03065 38130324c2ab84b52318852d75ae6842 569 Gene3D G3DSA:3.40.50.980 216 381 3.5E-42 T 29-03-2018 CDC59_RS03065 38130324c2ab84b52318852d75ae6842 569 SUPERFAMILY SSF56801 19 566 1.57E-150 T 29-03-2018 CDC59_RS03065 38130324c2ab84b52318852d75ae6842 569 ProSitePatterns PS00455 Putative AMP-binding domain signature. 210 221 - T 29-03-2018 IPR020845 AMP-binding, conserved site CDC59_RS03065 38130324c2ab84b52318852d75ae6842 569 Gene3D G3DSA:3.40.50.980 20 215 8.6E-42 T 29-03-2018 CDC59_RS17890 937e8bdc06c732c77a1633f5c4a0e180 277 Pfam PF04954 Siderophore-interacting protein 140 265 1.8E-30 T 29-03-2018 IPR007037 Siderophore-interacting protein CDC59_RS17890 937e8bdc06c732c77a1633f5c4a0e180 277 SUPERFAMILY SSF63380 22 139 6.99E-15 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CDC59_RS17890 937e8bdc06c732c77a1633f5c4a0e180 277 Pfam PF08021 Siderophore-interacting FAD-binding domain 72 131 1.1E-15 T 29-03-2018 IPR013113 FAD-binding 9, siderophore-interacting CDC59_RS17890 937e8bdc06c732c77a1633f5c4a0e180 277 Gene3D G3DSA:2.40.30.10 16 133 9.3E-28 T 29-03-2018 CDC59_RS17890 937e8bdc06c732c77a1633f5c4a0e180 277 Gene3D G3DSA:3.40.50.80 134 277 9.0E-36 T 29-03-2018 CDC59_RS02135 d8ed7c7386f585243792bf8cf63a0945 195 Gene3D G3DSA:2.30.30.30 136 195 2.8E-20 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 CDC59_RS02135 d8ed7c7386f585243792bf8cf63a0945 195 SMART SM00738 20 129 1.3E-45 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CDC59_RS02135 d8ed7c7386f585243792bf8cf63a0945 195 SUPERFAMILY SSF82679 21 131 8.11E-38 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CDC59_RS02135 d8ed7c7386f585243792bf8cf63a0945 195 Pfam PF02357 Transcription termination factor nusG 22 126 1.4E-26 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CDC59_RS02135 d8ed7c7386f585243792bf8cf63a0945 195 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 23 195 1.1E-67 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CDC59_RS02135 d8ed7c7386f585243792bf8cf63a0945 195 Pfam PF00467 KOW motif 144 178 4.0E-6 T 29-03-2018 IPR005824 KOW CDC59_RS02135 d8ed7c7386f585243792bf8cf63a0945 195 Gene3D G3DSA:3.30.70.940 20 133 2.1E-42 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CDC59_RS02135 d8ed7c7386f585243792bf8cf63a0945 195 PRINTS PR00338 Transcription termination factor NUSG signature 171 187 1.3E-19 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CDC59_RS02135 d8ed7c7386f585243792bf8cf63a0945 195 PRINTS PR00338 Transcription termination factor NUSG signature 75 87 1.3E-19 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CDC59_RS02135 d8ed7c7386f585243792bf8cf63a0945 195 PRINTS PR00338 Transcription termination factor NUSG signature 153 168 1.3E-19 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CDC59_RS02135 d8ed7c7386f585243792bf8cf63a0945 195 ProSitePatterns PS01014 Transcription termination factor nusG signature. 178 187 - T 29-03-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site CDC59_RS02135 d8ed7c7386f585243792bf8cf63a0945 195 SUPERFAMILY SSF50104 139 195 1.91E-19 T 29-03-2018 IPR008991 Translation protein SH3-like domain CDC59_RS02135 d8ed7c7386f585243792bf8cf63a0945 195 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 20 195 25.834 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CDC59_RS02135 d8ed7c7386f585243792bf8cf63a0945 195 SMART SM00739 141 168 2.2E-5 T 29-03-2018 IPR005824 KOW CDC59_RS13255 dc34bab82180df817aa7dd06cf57cc6d 448 SUPERFAMILY SSF75304 10 447 3.14E-109 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CDC59_RS13255 dc34bab82180df817aa7dd06cf57cc6d 448 Gene3D G3DSA:3.90.1300.10 8 448 1.3E-115 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CDC59_RS13255 dc34bab82180df817aa7dd06cf57cc6d 448 Pfam PF01425 Amidase 26 437 1.4E-83 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CDC59_RS23195 dfbc0d1d31c82038142e4009446a8398 549 SMART SM00304 221 273 9.1E-13 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CDC59_RS23195 dfbc0d1d31c82038142e4009446a8398 549 SUPERFAMILY SSF158472 221 270 1.03E-8 T 29-03-2018 CDC59_RS23195 dfbc0d1d31c82038142e4009446a8398 549 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 422 531 1.9E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS23195 dfbc0d1d31c82038142e4009446a8398 549 Pfam PF00672 HAMP domain 221 270 6.1E-11 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CDC59_RS23195 dfbc0d1d31c82038142e4009446a8398 549 Pfam PF00512 His Kinase A (phospho-acceptor) domain 307 372 2.7E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS23195 dfbc0d1d31c82038142e4009446a8398 549 Gene3D G3DSA:3.30.565.10 368 533 8.8E-42 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS23195 dfbc0d1d31c82038142e4009446a8398 549 SUPERFAMILY SSF47384 292 374 1.28E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS23195 dfbc0d1d31c82038142e4009446a8398 549 SMART SM00388 306 373 8.1E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS23195 dfbc0d1d31c82038142e4009446a8398 549 SUPERFAMILY SSF55874 362 534 4.06E-44 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS23195 dfbc0d1d31c82038142e4009446a8398 549 SMART SM00387 421 533 6.1E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS23195 dfbc0d1d31c82038142e4009446a8398 549 PRINTS PR00344 Bacterial sensor protein C-terminal signature 493 511 2.0E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS23195 dfbc0d1d31c82038142e4009446a8398 549 PRINTS PR00344 Bacterial sensor protein C-terminal signature 517 530 2.0E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS23195 dfbc0d1d31c82038142e4009446a8398 549 PRINTS PR00344 Bacterial sensor protein C-terminal signature 458 472 2.0E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS23195 dfbc0d1d31c82038142e4009446a8398 549 PRINTS PR00344 Bacterial sensor protein C-terminal signature 476 486 2.0E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS23195 dfbc0d1d31c82038142e4009446a8398 549 Gene3D G3DSA:1.10.287.130 296 367 2.3E-12 T 29-03-2018 CDC59_RS23740 3bc22de90e64335dbb491323c166fbc5 139 SMART SM00347 28 127 3.6E-4 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS23740 3bc22de90e64335dbb491323c166fbc5 139 Gene3D G3DSA:1.10.10.10 2 136 5.9E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS23740 3bc22de90e64335dbb491323c166fbc5 139 SUPERFAMILY SSF46785 5 137 4.86E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS06300 ed452d7356f65d9d9d4192c3fffc745c 305 SUPERFAMILY SSF103481 53 156 2.35E-12 T 29-03-2018 CDC59_RS06300 ed452d7356f65d9d9d4192c3fffc745c 305 SUPERFAMILY SSF103481 209 304 2.75E-13 T 29-03-2018 CDC59_RS06300 ed452d7356f65d9d9d4192c3fffc745c 305 Pfam PF00892 EamA-like transporter family 166 301 7.0E-17 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CDC59_RS06300 ed452d7356f65d9d9d4192c3fffc745c 305 Pfam PF00892 EamA-like transporter family 18 153 1.1E-12 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CDC59_RS08570 9feadb148111ae034428eee83dba191c 123 Pfam PF02033 Ribosome-binding factor A 11 112 4.9E-26 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CDC59_RS08570 9feadb148111ae034428eee83dba191c 123 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 10 116 2.3E-22 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CDC59_RS08570 9feadb148111ae034428eee83dba191c 123 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 7 119 19.46 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CDC59_RS08570 9feadb148111ae034428eee83dba191c 123 Gene3D G3DSA:3.30.300.20 9 119 3.5E-28 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CDC59_RS08570 9feadb148111ae034428eee83dba191c 123 SUPERFAMILY SSF89919 9 115 3.53E-29 T 29-03-2018 IPR023799 Ribosome-binding factor A domain CDC59_RS08570 9feadb148111ae034428eee83dba191c 123 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 14 99 1.0E-44 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CDC59_RS21830 a2a63e832167ab183463fc8b9e584b5b 289 Pfam PF01418 Helix-turn-helix domain, rpiR family 5 79 5.2E-16 T 29-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CDC59_RS21830 a2a63e832167ab183463fc8b9e584b5b 289 Pfam PF01380 SIS domain 126 252 1.4E-16 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CDC59_RS21830 a2a63e832167ab183463fc8b9e584b5b 289 SUPERFAMILY SSF53697 99 279 8.01E-33 T 29-03-2018 CDC59_RS21830 a2a63e832167ab183463fc8b9e584b5b 289 SUPERFAMILY SSF46689 4 77 7.35E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS21830 a2a63e832167ab183463fc8b9e584b5b 289 Gene3D G3DSA:3.40.50.10490 95 280 4.6E-32 T 29-03-2018 CDC59_RS21830 a2a63e832167ab183463fc8b9e584b5b 289 Gene3D G3DSA:1.10.10.10 1 80 6.2E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS02780 d5f7dcb21c04d02e3525d6bdcc8235d8 162 Pfam PF04073 Aminoacyl-tRNA editing domain 23 142 5.9E-28 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CDC59_RS02780 d5f7dcb21c04d02e3525d6bdcc8235d8 162 SUPERFAMILY SSF55826 9 146 5.36E-34 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CDC59_RS02780 d5f7dcb21c04d02e3525d6bdcc8235d8 162 Gene3D G3DSA:3.90.960.10 2 151 7.1E-28 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CDC59_RS04105 b744d7173dcdf978beac313197c2b895 655 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 193 206 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CDC59_RS04105 b744d7173dcdf978beac313197c2b895 655 SUPERFAMILY SSF100934 508 604 7.32E-23 T 29-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain CDC59_RS04105 b744d7173dcdf978beac313197c2b895 655 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 604 1.1E-290 T 29-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 CDC59_RS04105 b744d7173dcdf978beac313197c2b895 655 Pfam PF00012 Hsp70 protein 4 604 3.8E-263 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CDC59_RS04105 b744d7173dcdf978beac313197c2b895 655 SUPERFAMILY SSF53067 188 383 6.0E-68 T 29-03-2018 CDC59_RS04105 b744d7173dcdf978beac313197c2b895 655 SUPERFAMILY SSF53067 4 184 4.79E-64 T 29-03-2018 CDC59_RS04105 b744d7173dcdf978beac313197c2b895 655 PRINTS PR00301 70kDa heat shock protein signature 31 43 6.8E-79 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CDC59_RS04105 b744d7173dcdf978beac313197c2b895 655 PRINTS PR00301 70kDa heat shock protein signature 389 408 6.8E-79 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CDC59_RS04105 b744d7173dcdf978beac313197c2b895 655 PRINTS PR00301 70kDa heat shock protein signature 470 486 6.8E-79 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CDC59_RS04105 b744d7173dcdf978beac313197c2b895 655 PRINTS PR00301 70kDa heat shock protein signature 335 351 6.8E-79 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CDC59_RS04105 b744d7173dcdf978beac313197c2b895 655 PRINTS PR00301 70kDa heat shock protein signature 54 62 6.8E-79 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CDC59_RS04105 b744d7173dcdf978beac313197c2b895 655 PRINTS PR00301 70kDa heat shock protein signature 366 386 6.8E-79 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CDC59_RS04105 b744d7173dcdf978beac313197c2b895 655 PRINTS PR00301 70kDa heat shock protein signature 138 158 6.8E-79 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CDC59_RS04105 b744d7173dcdf978beac313197c2b895 655 PRINTS PR00301 70kDa heat shock protein signature 199 209 6.8E-79 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CDC59_RS04105 b744d7173dcdf978beac313197c2b895 655 PRINTS PR00301 70kDa heat shock protein signature 3 16 6.8E-79 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CDC59_RS04105 b744d7173dcdf978beac313197c2b895 655 SUPERFAMILY SSF100920 385 540 9.29E-61 T 29-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CDC59_RS04105 b744d7173dcdf978beac313197c2b895 655 Gene3D G3DSA:2.60.34.10 391 532 5.7E-66 T 29-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CDC59_RS04105 b744d7173dcdf978beac313197c2b895 655 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 338 352 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CDC59_RS04105 b744d7173dcdf978beac313197c2b895 655 Gene3D G3DSA:3.30.420.40 198 367 4.3E-47 T 29-03-2018 CDC59_RS04105 b744d7173dcdf978beac313197c2b895 655 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 651 36.806 T 29-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 CDC59_RS04105 b744d7173dcdf978beac313197c2b895 655 Gene3D G3DSA:3.30.420.40 1 197 2.1E-79 T 29-03-2018 CDC59_RS04105 b744d7173dcdf978beac313197c2b895 655 Gene3D G3DSA:1.20.1270.10 533 619 2.8E-23 T 29-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain CDC59_RS04105 b744d7173dcdf978beac313197c2b895 655 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CDC59_RS11635 3be2d7cb6e2fdf439cd0eb68317c9b52 313 Pfam PF00487 Fatty acid desaturase 64 294 1.1E-22 T 29-03-2018 IPR005804 Fatty acid desaturase domain GO:0006629 CDC59_RS04945 8e6f85003001c92da164bfd2b057a24d 137 ProSitePatterns PS00550 Hemerythrin family signature. 53 76 - T 29-03-2018 IPR016131 Haemerythrin, iron-binding site GO:0046872 CDC59_RS04945 8e6f85003001c92da164bfd2b057a24d 137 Pfam PF01814 Hemerythrin HHE cation binding domain 15 120 3.1E-12 T 29-03-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 CDC59_RS04945 8e6f85003001c92da164bfd2b057a24d 137 SUPERFAMILY SSF47188 1 124 1.44E-26 T 29-03-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 CDC59_RS04945 8e6f85003001c92da164bfd2b057a24d 137 TIGRFAM TIGR02481 hemeryth_dom: hemerythrin-like metal-binding domain 5 124 5.0E-21 T 29-03-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 CDC59_RS04945 8e6f85003001c92da164bfd2b057a24d 137 Gene3D G3DSA:1.20.120.50 1 129 7.2E-28 T 29-03-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 CDC59_RS22810 2af905e8ab846c8c63a2aa99285cf5db 235 SUPERFAMILY SSF81452 23 235 1.1E-50 T 29-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS22810 2af905e8ab846c8c63a2aa99285cf5db 235 Gene3D G3DSA:1.20.120.80 38 235 1.7E-57 T 29-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS22810 2af905e8ab846c8c63a2aa99285cf5db 235 Pfam PF00510 Cytochrome c oxidase subunit III 45 235 6.3E-22 T 29-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS19285 cad5125e616e7473413ab4987cb390b5 190 SUPERFAMILY SSF48150 1 184 4.4E-78 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CDC59_RS19285 cad5125e616e7473413ab4987cb390b5 190 TIGRFAM TIGR00624 tag: DNA-3-methyladenine glycosylase I 3 181 3.5E-70 T 29-03-2018 IPR004597 DNA-3-methyladenine glycosylase I GO:0006284|GO:0008725 CDC59_RS19285 cad5125e616e7473413ab4987cb390b5 190 Pfam PF03352 Methyladenine glycosylase 6 181 7.5E-78 T 29-03-2018 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 CDC59_RS19285 cad5125e616e7473413ab4987cb390b5 190 Gene3D G3DSA:1.10.340.30 1 182 4.2E-81 T 29-03-2018 CDC59_RS22190 f21bdd6cb6966cea02267b55b647f20f 254 Pfam PF00455 DeoR C terminal sensor domain 75 229 3.2E-42 T 29-03-2018 IPR014036 DeoR C-terminal sensor domain CDC59_RS22190 f21bdd6cb6966cea02267b55b647f20f 254 Gene3D G3DSA:3.40.50.1360 72 234 1.5E-39 T 29-03-2018 CDC59_RS22190 f21bdd6cb6966cea02267b55b647f20f 254 SUPERFAMILY SSF100950 76 232 3.35E-29 T 29-03-2018 CDC59_RS22190 f21bdd6cb6966cea02267b55b647f20f 254 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 23 37 3.8E-5 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CDC59_RS22190 f21bdd6cb6966cea02267b55b647f20f 254 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 37 55 3.8E-5 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CDC59_RS22190 f21bdd6cb6966cea02267b55b647f20f 254 Gene3D G3DSA:1.10.10.10 3 71 3.7E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS22190 f21bdd6cb6966cea02267b55b647f20f 254 SMART SM01134 72 231 1.1E-58 T 29-03-2018 CDC59_RS22190 f21bdd6cb6966cea02267b55b647f20f 254 SMART SM00420 6 57 1.4E-7 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CDC59_RS22190 f21bdd6cb6966cea02267b55b647f20f 254 Pfam PF08220 DeoR-like helix-turn-helix domain 6 58 1.0E-10 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CDC59_RS22190 f21bdd6cb6966cea02267b55b647f20f 254 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 39 - T 29-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CDC59_RS22190 f21bdd6cb6966cea02267b55b647f20f 254 SUPERFAMILY SSF46785 3 62 9.0E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS14200 2c5319d23c863aeef25b835fac31025f 659 Gene3D G3DSA:3.40.50.720 402 527 1.5E-25 T 29-03-2018 CDC59_RS14200 2c5319d23c863aeef25b835fac31025f 659 SUPERFAMILY SSF116726 578 656 5.89E-13 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CDC59_RS14200 2c5319d23c863aeef25b835fac31025f 659 Pfam PF00999 Sodium/hydrogen exchanger family 8 376 1.6E-64 T 29-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CDC59_RS14200 2c5319d23c863aeef25b835fac31025f 659 Gene3D G3DSA:3.30.70.1450 576 659 3.7E-12 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CDC59_RS14200 2c5319d23c863aeef25b835fac31025f 659 Gene3D G3DSA:1.20.91.10 232 314 4.7E-12 T 29-03-2018 CDC59_RS14200 2c5319d23c863aeef25b835fac31025f 659 Pfam PF02254 TrkA-N domain 413 526 4.9E-23 T 29-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CDC59_RS14200 2c5319d23c863aeef25b835fac31025f 659 SUPERFAMILY SSF51735 410 550 5.1E-33 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS14200 2c5319d23c863aeef25b835fac31025f 659 Pfam PF02080 TrkA-C domain 589 656 7.1E-11 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CDC59_RS19720 ae686cccb2ff4a4b5c03a68044c28d2c 457 Pfam PF02638 Glycosyl hydrolase-like 10 71 406 2.7E-96 T 29-03-2018 IPR003790 Glycosyl hydrolase-like 10 CDC59_RS19720 ae686cccb2ff4a4b5c03a68044c28d2c 457 Gene3D G3DSA:3.20.20.80 45 350 2.8E-41 T 29-03-2018 CDC59_RS19720 ae686cccb2ff4a4b5c03a68044c28d2c 457 SUPERFAMILY SSF51445 99 389 3.94E-29 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CDC59_RS02285 92edb8bdc7fffcdaa4d6d657f101e6a9 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 29-03-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS02285 92edb8bdc7fffcdaa4d6d657f101e6a9 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 2.7E-54 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CDC59_RS02285 92edb8bdc7fffcdaa4d6d657f101e6a9 122 SUPERFAMILY SSF50193 1 122 2.62E-50 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CDC59_RS02285 92edb8bdc7fffcdaa4d6d657f101e6a9 122 Gene3D G3DSA:2.40.150.20 1 122 2.0E-51 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CDC59_RS02285 92edb8bdc7fffcdaa4d6d657f101e6a9 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 27.199 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CDC59_RS02285 92edb8bdc7fffcdaa4d6d657f101e6a9 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 2.5E-57 T 29-03-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 CDC59_RS02285 92edb8bdc7fffcdaa4d6d657f101e6a9 122 SMART SM01374 1 122 9.2E-85 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CDC59_RS09725 c515e9712c7238d25be74a56c576cf73 622 Gene3D G3DSA:1.20.140.10 321 490 1.7E-37 T 29-03-2018 CDC59_RS09725 c515e9712c7238d25be74a56c576cf73 622 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 6 34 1.5E-10 T 29-03-2018 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria CDC59_RS09725 c515e9712c7238d25be74a56c576cf73 622 Gene3D G3DSA:1.10.540.10 7 158 1.1E-10 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CDC59_RS09725 c515e9712c7238d25be74a56c576cf73 622 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 162 277 2.4E-12 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CDC59_RS09725 c515e9712c7238d25be74a56c576cf73 622 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 306 474 3.5E-17 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CDC59_RS09725 c515e9712c7238d25be74a56c576cf73 622 SUPERFAMILY SSF47203 310 483 4.99E-37 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CDC59_RS09725 c515e9712c7238d25be74a56c576cf73 622 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 494 618 5.4E-32 T 29-03-2018 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain CDC59_RS09725 c515e9712c7238d25be74a56c576cf73 622 SUPERFAMILY SSF56645 36 278 2.75E-41 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CDC59_RS09725 c515e9712c7238d25be74a56c576cf73 622 Gene3D G3DSA:2.40.110.10 160 280 2.9E-20 T 29-03-2018 CDC59_RS08260 ab262cf4fc4e63b7fa4bb2834bd2c748 514 SMART SM00283 259 506 8.5E-86 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CDC59_RS08260 ab262cf4fc4e63b7fa4bb2834bd2c748 514 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 357 384 2.1E-54 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS08260 ab262cf4fc4e63b7fa4bb2834bd2c748 514 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 280 309 2.1E-54 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS08260 ab262cf4fc4e63b7fa4bb2834bd2c748 514 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 434 463 2.1E-54 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS08260 ab262cf4fc4e63b7fa4bb2834bd2c748 514 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 39 54 2.1E-54 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS08260 ab262cf4fc4e63b7fa4bb2834bd2c748 514 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 386 415 2.1E-54 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS08260 ab262cf4fc4e63b7fa4bb2834bd2c748 514 SMART SM00304 206 258 1.1E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CDC59_RS08260 ab262cf4fc4e63b7fa4bb2834bd2c748 514 SUPERFAMILY SSF58104 226 507 4.84E-72 T 29-03-2018 CDC59_RS08260 ab262cf4fc4e63b7fa4bb2834bd2c748 514 Gene3D G3DSA:1.10.287.950 26 313 2.2E-14 T 29-03-2018 CDC59_RS08260 ab262cf4fc4e63b7fa4bb2834bd2c748 514 Gene3D G3DSA:1.10.287.950 314 510 1.9E-49 T 29-03-2018 CDC59_RS08260 ab262cf4fc4e63b7fa4bb2834bd2c748 514 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 318 474 7.0E-52 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CDC59_RS08260 ab262cf4fc4e63b7fa4bb2834bd2c748 514 Pfam PF00672 HAMP domain 206 254 1.4E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CDC59_RS09710 67de3669941d02bc24589b5a05d2df89 693 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 603 689 2.3E-9 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CDC59_RS09710 67de3669941d02bc24589b5a05d2df89 693 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 475 567 5.2E-23 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CDC59_RS09710 67de3669941d02bc24589b5a05d2df89 693 SUPERFAMILY SSF48179 474 616 5.36E-26 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CDC59_RS09710 67de3669941d02bc24589b5a05d2df89 693 Gene3D G3DSA:1.10.1040.10 474 572 7.9E-25 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CDC59_RS09710 67de3669941d02bc24589b5a05d2df89 693 Gene3D G3DSA:1.10.1040.10 598 692 2.2E-18 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CDC59_RS09710 67de3669941d02bc24589b5a05d2df89 693 Gene3D G3DSA:3.40.50.720 248 473 3.0E-61 T 29-03-2018 CDC59_RS09710 67de3669941d02bc24589b5a05d2df89 693 SUPERFAMILY SSF52096 5 286 6.7E-61 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CDC59_RS09710 67de3669941d02bc24589b5a05d2df89 693 SUPERFAMILY SSF51735 291 470 2.02E-56 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS09710 67de3669941d02bc24589b5a05d2df89 693 Gene3D G3DSA:3.90.226.10 1 247 4.5E-54 T 29-03-2018 CDC59_RS09710 67de3669941d02bc24589b5a05d2df89 693 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 294 470 1.3E-61 T 29-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CDC59_RS09710 67de3669941d02bc24589b5a05d2df89 693 SUPERFAMILY SSF48179 597 691 6.12E-24 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CDC59_RS09710 67de3669941d02bc24589b5a05d2df89 693 Pfam PF00378 Enoyl-CoA hydratase/isomerase 8 190 2.8E-37 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CDC59_RS21475 d57ffdaffaa54b3b3fe87e5aeb9b63c0 463 PRINTS PR00811 Bacterial general secretion pathway protein D signature 403 417 2.8E-14 T 29-03-2018 IPR001775 GspD/PilQ family CDC59_RS21475 d57ffdaffaa54b3b3fe87e5aeb9b63c0 463 PRINTS PR00811 Bacterial general secretion pathway protein D signature 290 300 2.8E-14 T 29-03-2018 IPR001775 GspD/PilQ family CDC59_RS21475 d57ffdaffaa54b3b3fe87e5aeb9b63c0 463 PRINTS PR00811 Bacterial general secretion pathway protein D signature 251 275 2.8E-14 T 29-03-2018 IPR001775 GspD/PilQ family CDC59_RS21475 d57ffdaffaa54b3b3fe87e5aeb9b63c0 463 PRINTS PR00811 Bacterial general secretion pathway protein D signature 380 398 2.8E-14 T 29-03-2018 IPR001775 GspD/PilQ family CDC59_RS21475 d57ffdaffaa54b3b3fe87e5aeb9b63c0 463 Pfam PF13629 Pilus formation protein N terminal region 35 105 4.7E-18 T 29-03-2018 IPR032789 Pilus formation protein, N-terminal CDC59_RS21475 d57ffdaffaa54b3b3fe87e5aeb9b63c0 463 Pfam PF00263 Bacterial type II and III secretion system protein 256 416 2.1E-46 T 29-03-2018 IPR004846 Type II/III secretion system GO:0009306 CDC59_RS03250 542a3b35bd5d24849dc21f0f454f08b6 86 Gene3D G3DSA:2.40.50.100 20 85 2.9E-28 T 29-03-2018 CDC59_RS03250 542a3b35bd5d24849dc21f0f454f08b6 86 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 85 28.139 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS03250 542a3b35bd5d24849dc21f0f454f08b6 86 Pfam PF01016 Ribosomal L27 protein 2 82 1.6E-35 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS03250 542a3b35bd5d24849dc21f0f454f08b6 86 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 29-03-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS03250 542a3b35bd5d24849dc21f0f454f08b6 86 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 83 1.5E-37 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS03250 542a3b35bd5d24849dc21f0f454f08b6 86 SUPERFAMILY SSF110324 2 80 1.19E-31 T 29-03-2018 CDC59_RS03250 542a3b35bd5d24849dc21f0f454f08b6 86 PRINTS PR00063 Ribosomal protein L27 signature 29 53 2.6E-37 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS03250 542a3b35bd5d24849dc21f0f454f08b6 86 PRINTS PR00063 Ribosomal protein L27 signature 4 28 2.6E-37 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS03250 542a3b35bd5d24849dc21f0f454f08b6 86 PRINTS PR00063 Ribosomal protein L27 signature 54 78 2.6E-37 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS03250 542a3b35bd5d24849dc21f0f454f08b6 86 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 43 69 5.0E-9 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS11370 bf4f87a9d9b31c9c2b7caa251c18541d 321 TIGRFAM TIGR01288 nodI: nodulation ABC transporter NodI 19 321 5.7E-143 T 29-03-2018 IPR005978 Nodulation ABC transporter, NodI GO:0005215|GO:0005524|GO:0006810|GO:0009877|GO:0016020 CDC59_RS11370 bf4f87a9d9b31c9c2b7caa251c18541d 321 SUPERFAMILY SSF52540 15 237 2.25E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS11370 bf4f87a9d9b31c9c2b7caa251c18541d 321 SMART SM00382 41 224 6.7E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS11370 bf4f87a9d9b31c9c2b7caa251c18541d 321 Gene3D G3DSA:3.40.50.300 13 291 7.8E-68 T 29-03-2018 CDC59_RS11370 bf4f87a9d9b31c9c2b7caa251c18541d 321 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS11370 bf4f87a9d9b31c9c2b7caa251c18541d 321 Pfam PF00005 ABC transporter 33 175 2.6E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS12670 57959d7828f245a4ab483c4f39550a29 762 SUPERFAMILY SSF52540 169 422 9.32E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS12670 57959d7828f245a4ab483c4f39550a29 762 SUPERFAMILY SSF81923 1 143 2.62E-57 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CDC59_RS12670 57959d7828f245a4ab483c4f39550a29 762 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 534 552 1.1E-38 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CDC59_RS12670 57959d7828f245a4ab483c4f39550a29 762 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 563 581 1.1E-38 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CDC59_RS12670 57959d7828f245a4ab483c4f39550a29 762 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 492 510 1.1E-38 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CDC59_RS12670 57959d7828f245a4ab483c4f39550a29 762 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 596 610 1.1E-38 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CDC59_RS12670 57959d7828f245a4ab483c4f39550a29 762 SMART SM01086 654 746 4.3E-31 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CDC59_RS12670 57959d7828f245a4ab483c4f39550a29 762 Gene3D G3DSA:1.10.1780.10 3 153 4.5E-24 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CDC59_RS12670 57959d7828f245a4ab483c4f39550a29 762 Gene3D G3DSA:3.40.50.300 453 653 9.0E-42 T 29-03-2018 CDC59_RS12670 57959d7828f245a4ab483c4f39550a29 762 Gene3D G3DSA:1.10.8.60 654 760 6.4E-21 T 29-03-2018 CDC59_RS12670 57959d7828f245a4ab483c4f39550a29 762 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 303 315 - T 29-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 CDC59_RS12670 57959d7828f245a4ab483c4f39550a29 762 SUPERFAMILY SSF52540 438 741 3.13E-78 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS12670 57959d7828f245a4ab483c4f39550a29 762 TIGRFAM TIGR02639 ClpA: ATP-dependent Clp protease ATP-binding subunit ClpA 3 735 0.0 T 29-03-2018 IPR013461 ATP-dependent Clp protease ATP-binding subunit ClpA GO:0004176 CDC59_RS12670 57959d7828f245a4ab483c4f39550a29 762 SMART SM00382 488 664 2.9E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS12670 57959d7828f245a4ab483c4f39550a29 762 SMART SM00382 207 352 1.4E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS12670 57959d7828f245a4ab483c4f39550a29 762 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 654 734 4.8E-21 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CDC59_RS12670 57959d7828f245a4ab483c4f39550a29 762 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 13 62 1.8E-14 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CDC59_RS12670 57959d7828f245a4ab483c4f39550a29 762 Pfam PF07724 AAA domain (Cdc48 subfamily) 487 647 2.5E-47 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CDC59_RS12670 57959d7828f245a4ab483c4f39550a29 762 Gene3D G3DSA:3.40.50.300 166 351 1.5E-25 T 29-03-2018 CDC59_RS12670 57959d7828f245a4ab483c4f39550a29 762 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 212 324 4.7E-11 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CDC59_RS12670 57959d7828f245a4ab483c4f39550a29 762 Gene3D G3DSA:1.10.8.60 352 452 3.0E-28 T 29-03-2018 CDC59_RS12670 57959d7828f245a4ab483c4f39550a29 762 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 519 537 - T 29-03-2018 IPR028299 ClpA/B, conserved site 2 CDC59_RS12395 2243b4c93c0c83feb26f684d096c2263 311 Gene3D G3DSA:1.10.10.10 1 91 1.7E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS12395 2243b4c93c0c83feb26f684d096c2263 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.1E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS12395 2243b4c93c0c83feb26f684d096c2263 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.1E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS12395 2243b4c93c0c83feb26f684d096c2263 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.1E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS12395 2243b4c93c0c83feb26f684d096c2263 311 SUPERFAMILY SSF46785 1 85 7.9E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS12395 2243b4c93c0c83feb26f684d096c2263 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 2.9E-22 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS12395 2243b4c93c0c83feb26f684d096c2263 311 Gene3D G3DSA:3.40.190.10 181 276 1.1E-13 T 29-03-2018 CDC59_RS12395 2243b4c93c0c83feb26f684d096c2263 311 Gene3D G3DSA:3.40.190.10 92 180 4.0E-15 T 29-03-2018 CDC59_RS12395 2243b4c93c0c83feb26f684d096c2263 311 SUPERFAMILY SSF53850 90 299 2.26E-33 T 29-03-2018 CDC59_RS12395 2243b4c93c0c83feb26f684d096c2263 311 Pfam PF03466 LysR substrate binding domain 88 300 3.8E-36 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS06465 e8945d3dd9db219f67e3831a3d7c2cec 810 Pfam PF13291 ACT domain 726 805 1.6E-15 T 29-03-2018 IPR002912 ACT domain CDC59_RS06465 e8945d3dd9db219f67e3831a3d7c2cec 810 SMART SM00954 324 434 5.5E-61 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 CDC59_RS06465 e8945d3dd9db219f67e3831a3d7c2cec 810 SUPERFAMILY SSF81301 281 454 2.13E-59 T 29-03-2018 CDC59_RS06465 e8945d3dd9db219f67e3831a3d7c2cec 810 Pfam PF04607 Region found in RelA / SpoT proteins 324 434 8.2E-34 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 CDC59_RS06465 e8945d3dd9db219f67e3831a3d7c2cec 810 Gene3D G3DSA:3.10.20.30 471 546 1.5E-22 T 29-03-2018 IPR012675 Beta-grasp domain CDC59_RS06465 e8945d3dd9db219f67e3831a3d7c2cec 810 Pfam PF13328 HD domain 115 264 5.1E-52 T 29-03-2018 IPR003607 HD/PDEase domain CDC59_RS06465 e8945d3dd9db219f67e3831a3d7c2cec 810 Gene3D G3DSA:3.30.70.260 726 809 2.2E-10 T 29-03-2018 CDC59_RS06465 e8945d3dd9db219f67e3831a3d7c2cec 810 SUPERFAMILY SSF55021 728 804 7.5E-8 T 29-03-2018 CDC59_RS06465 e8945d3dd9db219f67e3831a3d7c2cec 810 SUPERFAMILY SSF109604 100 278 8.16E-72 T 29-03-2018 CDC59_RS06465 e8945d3dd9db219f67e3831a3d7c2cec 810 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 115 804 5.8E-223 T 29-03-2018 IPR004811 RelA/SpoT family GO:0015969 CDC59_RS06465 e8945d3dd9db219f67e3831a3d7c2cec 810 Pfam PF02824 TGS domain 477 536 4.3E-19 T 29-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 CDC59_RS06465 e8945d3dd9db219f67e3831a3d7c2cec 810 Gene3D G3DSA:3.30.460.10 282 414 3.1E-38 T 29-03-2018 CDC59_RS06465 e8945d3dd9db219f67e3831a3d7c2cec 810 SMART SM00471 130 242 4.7E-10 T 29-03-2018 IPR003607 HD/PDEase domain CDC59_RS06465 e8945d3dd9db219f67e3831a3d7c2cec 810 SUPERFAMILY SSF81271 464 536 1.31E-21 T 29-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CDC59_RS18955 d87ac6c06275085ffb189125a5a66fff 349 Pfam PF05138 Phenylacetic acid catabolic protein 42 316 2.0E-101 T 29-03-2018 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 CDC59_RS18955 d87ac6c06275085ffb189125a5a66fff 349 Gene3D G3DSA:1.10.620.20 22 319 4.1E-78 T 29-03-2018 CDC59_RS18955 d87ac6c06275085ffb189125a5a66fff 349 TIGRFAM TIGR02156 PA_CoA_Oxy1: phenylacetate-CoA oxygenase, PaaG subunit 32 320 3.0E-158 T 29-03-2018 IPR011881 1,2-phenylacetyl-CoA epoxidase, subunit A GO:0010124|GO:0097266 KEGG: 00360+1.14.13.14+1.14.13.149|KEGG: 00940+1.14.13.14|MetaCyc: PWY-5176 CDC59_RS18955 d87ac6c06275085ffb189125a5a66fff 349 SUPERFAMILY SSF47240 52 294 1.26E-80 T 29-03-2018 IPR009078 Ferritin-like superfamily CDC59_RS13775 3a6fae4b6a7affa027904c45fce7e95d 124 Gene3D G3DSA:2.60.300.12 19 124 1.0E-39 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CDC59_RS13775 3a6fae4b6a7affa027904c45fce7e95d 124 Hamap MF_01380 Iron-sulfur cluster insertion protein ErpA [erpA]. 1 124 36.904 T 29-03-2018 IPR023063 FeS cluster insertion protein ErpA GO:0097428 CDC59_RS13775 3a6fae4b6a7affa027904c45fce7e95d 124 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 105 122 - T 29-03-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 CDC59_RS13775 3a6fae4b6a7affa027904c45fce7e95d 124 Pfam PF01521 Iron-sulphur cluster biosynthesis 19 119 3.5E-21 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CDC59_RS13775 3a6fae4b6a7affa027904c45fce7e95d 124 SUPERFAMILY SSF89360 17 110 4.05E-32 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CDC59_RS13775 3a6fae4b6a7affa027904c45fce7e95d 124 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 21 124 1.9E-39 T 29-03-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 CDC59_RS02060 ab1e06cdf0ef1cef0fa4846096f4ff76 525 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 40 52 1.7E-26 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CDC59_RS02060 ab1e06cdf0ef1cef0fa4846096f4ff76 525 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 24 34 1.7E-26 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CDC59_RS02060 ab1e06cdf0ef1cef0fa4846096f4ff76 525 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 85 97 1.7E-26 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CDC59_RS02060 ab1e06cdf0ef1cef0fa4846096f4ff76 525 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 321 327 1.7E-26 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CDC59_RS02060 ab1e06cdf0ef1cef0fa4846096f4ff76 525 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 11 23 1.7E-26 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CDC59_RS02060 ab1e06cdf0ef1cef0fa4846096f4ff76 525 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 357 369 1.7E-26 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CDC59_RS02060 ab1e06cdf0ef1cef0fa4846096f4ff76 525 Gene3D G3DSA:3.40.50.720 10 62 4.9E-4 T 29-03-2018 CDC59_RS02060 ab1e06cdf0ef1cef0fa4846096f4ff76 525 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 362 372 - T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CDC59_RS02060 ab1e06cdf0ef1cef0fa4846096f4ff76 525 Pfam PF01266 FAD dependent oxidoreductase 12 352 6.9E-55 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CDC59_RS02060 ab1e06cdf0ef1cef0fa4846096f4ff76 525 SUPERFAMILY SSF51905 11 330 2.36E-34 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS02060 ab1e06cdf0ef1cef0fa4846096f4ff76 525 Gene3D G3DSA:3.30.9.10 89 195 3.5E-19 T 29-03-2018 CDC59_RS02060 ab1e06cdf0ef1cef0fa4846096f4ff76 525 Gene3D G3DSA:3.30.9.10 196 328 4.4E-35 T 29-03-2018 CDC59_RS02060 ab1e06cdf0ef1cef0fa4846096f4ff76 525 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 16 33 - T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CDC59_RS02060 ab1e06cdf0ef1cef0fa4846096f4ff76 525 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 392 499 4.0E-13 T 29-03-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CDC59_RS07100 4505d353f694f0e7d4804c69d23a00a0 398 Gene3D G3DSA:3.90.1150.10 304 398 9.3E-31 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS07100 4505d353f694f0e7d4804c69d23a00a0 398 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 245 258 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CDC59_RS07100 4505d353f694f0e7d4804c69d23a00a0 398 Gene3D G3DSA:3.40.640.10 72 302 3.6E-33 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDC59_RS07100 4505d353f694f0e7d4804c69d23a00a0 398 Gene3D G3DSA:3.90.1150.10 2 71 2.3E-15 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS07100 4505d353f694f0e7d4804c69d23a00a0 398 SUPERFAMILY SSF53383 1 398 8.88E-123 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS07100 4505d353f694f0e7d4804c69d23a00a0 398 PRINTS PR00799 Aspartate aminotransferase signature 177 196 1.3E-38 T 29-03-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 CDC59_RS07100 4505d353f694f0e7d4804c69d23a00a0 398 PRINTS PR00799 Aspartate aminotransferase signature 208 220 1.3E-38 T 29-03-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 CDC59_RS07100 4505d353f694f0e7d4804c69d23a00a0 398 PRINTS PR00799 Aspartate aminotransferase signature 343 361 1.3E-38 T 29-03-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 CDC59_RS07100 4505d353f694f0e7d4804c69d23a00a0 398 PRINTS PR00799 Aspartate aminotransferase signature 275 300 1.3E-38 T 29-03-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 CDC59_RS07100 4505d353f694f0e7d4804c69d23a00a0 398 Pfam PF00155 Aminotransferase class I and II 29 394 7.4E-84 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CDC59_RS06530 c0fc33833003222f868ccb4b3a5fd55c 173 Gene3D G3DSA:1.10.3330.10 5 173 2.6E-56 T 29-03-2018 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 CDC59_RS06530 c0fc33833003222f868ccb4b3a5fd55c 173 Pfam PF09349 OHCU decarboxylase 12 167 6.0E-47 T 29-03-2018 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 CDC59_RS06530 c0fc33833003222f868ccb4b3a5fd55c 173 SUPERFAMILY SSF158694 7 171 1.31E-55 T 29-03-2018 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 CDC59_RS06530 c0fc33833003222f868ccb4b3a5fd55c 173 TIGRFAM TIGR03164 UHCUDC: OHCU decarboxylase 14 170 1.1E-64 T 29-03-2018 IPR017580 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase, type 1 GO:0019428 KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 CDC59_RS12095 685c2773bda55f98a8a874a14314266d 546 Gene3D G3DSA:3.40.50.620 270 546 6.8E-67 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDC59_RS12095 685c2773bda55f98a8a874a14314266d 546 Gene3D G3DSA:3.60.110.10 1 258 2.6E-58 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CDC59_RS12095 685c2773bda55f98a8a874a14314266d 546 Pfam PF00795 Carbon-nitrogen hydrolase 4 253 6.1E-29 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CDC59_RS12095 685c2773bda55f98a8a874a14314266d 546 Pfam PF02540 NAD synthase 273 521 5.7E-72 T 29-03-2018 IPR022310 NAD/GMP synthase CDC59_RS12095 685c2773bda55f98a8a874a14314266d 546 SUPERFAMILY SSF56317 3 254 9.42E-61 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CDC59_RS12095 685c2773bda55f98a8a874a14314266d 546 TIGRFAM TIGR00552 nadE: NAD+ synthetase 277 525 8.7E-60 T 29-03-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 CDC59_RS12095 685c2773bda55f98a8a874a14314266d 546 SUPERFAMILY SSF52402 269 529 1.65E-74 T 29-03-2018 CDC59_RS12095 685c2773bda55f98a8a874a14314266d 546 PIRSF PIRSF006630 1 258 2.4E-72 T 29-03-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 CDC59_RS12095 685c2773bda55f98a8a874a14314266d 546 PIRSF PIRSF006630 254 546 9.0E-120 T 29-03-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 CDC59_RS13840 24bb581392222cd80ccc4a894a4ad1fa 227 SUPERFAMILY SSF161098 18 217 4.32E-39 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS13840 24bb581392222cd80ccc4a894a4ad1fa 227 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 15 120 7.6E-24 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CDC59_RS13840 24bb581392222cd80ccc4a894a4ad1fa 227 Gene3D G3DSA:1.10.3720.10 10 227 6.3E-39 T 29-03-2018 CDC59_RS13840 24bb581392222cd80ccc4a894a4ad1fa 227 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 36 226 1.5E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS05005 419f383a461d5c2ea24196fd66364993 73 Pfam PF13275 S4 domain 7 69 9.1E-24 T 29-03-2018 CDC59_RS05005 419f383a461d5c2ea24196fd66364993 73 Gene3D G3DSA:3.10.290.10 1 71 6.3E-13 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CDC59_RS05005 419f383a461d5c2ea24196fd66364993 73 SUPERFAMILY SSF55174 4 69 2.19E-18 T 29-03-2018 CDC59_RS13685 b1971c95ac0797b20865721c23ef29a8 458 Pfam PF05195 Aminopeptidase P, N-terminal domain 13 131 3.3E-33 T 29-03-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 CDC59_RS13685 b1971c95ac0797b20865721c23ef29a8 458 Gene3D G3DSA:3.40.350.10 9 180 4.2E-43 T 29-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CDC59_RS13685 b1971c95ac0797b20865721c23ef29a8 458 Gene3D G3DSA:3.90.230.10 181 458 9.1E-82 T 29-03-2018 CDC59_RS13685 b1971c95ac0797b20865721c23ef29a8 458 SUPERFAMILY SSF55920 185 456 4.97E-80 T 29-03-2018 IPR000994 Peptidase M24 CDC59_RS13685 b1971c95ac0797b20865721c23ef29a8 458 Pfam PF00557 Metallopeptidase family M24 190 433 3.4E-61 T 29-03-2018 IPR000994 Peptidase M24 CDC59_RS13685 b1971c95ac0797b20865721c23ef29a8 458 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 361 373 - T 29-03-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site CDC59_RS13685 b1971c95ac0797b20865721c23ef29a8 458 SMART SM01011 7 145 1.6E-58 T 29-03-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 CDC59_RS13685 b1971c95ac0797b20865721c23ef29a8 458 SUPERFAMILY SSF53092 12 183 7.5E-48 T 29-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal CDC59_RS21075 6f2671fdce194f97d97f05c2426a9eeb 117 Pfam PF05899 Protein of unknown function (DUF861) 42 112 2.2E-20 T 29-03-2018 IPR008579 Domain of unknown function DUF861, cupin-3 KEGG: 00230+3.5.3.26|MetaCyc: PWY-5692|MetaCyc: PWY-5698 CDC59_RS21075 6f2671fdce194f97d97f05c2426a9eeb 117 SUPERFAMILY SSF51182 35 114 4.45E-15 T 29-03-2018 IPR011051 RmlC-like cupin domain CDC59_RS21075 6f2671fdce194f97d97f05c2426a9eeb 117 Gene3D G3DSA:2.60.120.10 15 117 8.7E-13 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CDC59_RS03320 38dc72ff7331b83196b179c7bfda1fe6 558 SUPERFAMILY SSF52172 11 190 1.02E-38 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS03320 38dc72ff7331b83196b179c7bfda1fe6 558 Pfam PF02954 Bacterial regulatory protein, Fis family 498 538 9.4E-16 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CDC59_RS03320 38dc72ff7331b83196b179c7bfda1fe6 558 SUPERFAMILY SSF52540 148 388 1.55E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS03320 38dc72ff7331b83196b179c7bfda1fe6 558 SMART SM00382 166 310 1.1E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS03320 38dc72ff7331b83196b179c7bfda1fe6 558 SUPERFAMILY SSF46689 361 397 2.33E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS03320 38dc72ff7331b83196b179c7bfda1fe6 558 SUPERFAMILY SSF46689 488 540 2.33E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS03320 38dc72ff7331b83196b179c7bfda1fe6 558 Gene3D G3DSA:1.10.10.60 484 544 3.1E-14 T 29-03-2018 CDC59_RS03320 38dc72ff7331b83196b179c7bfda1fe6 558 Pfam PF00072 Response regulator receiver domain 11 119 1.1E-22 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS03320 38dc72ff7331b83196b179c7bfda1fe6 558 Gene3D G3DSA:3.40.50.2300 7 137 2.1E-30 T 29-03-2018 CDC59_RS03320 38dc72ff7331b83196b179c7bfda1fe6 558 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 504 521 1.9E-9 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CDC59_RS03320 38dc72ff7331b83196b179c7bfda1fe6 558 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 521 541 1.9E-9 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CDC59_RS03320 38dc72ff7331b83196b179c7bfda1fe6 558 Gene3D G3DSA:1.10.8.60 319 392 2.4E-22 T 29-03-2018 CDC59_RS03320 38dc72ff7331b83196b179c7bfda1fe6 558 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 360 369 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site CDC59_RS03320 38dc72ff7331b83196b179c7bfda1fe6 558 Gene3D G3DSA:3.40.50.300 142 318 2.0E-24 T 29-03-2018 CDC59_RS03320 38dc72ff7331b83196b179c7bfda1fe6 558 SMART SM00448 9 120 1.8E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS03320 38dc72ff7331b83196b179c7bfda1fe6 558 Pfam PF00158 Sigma-54 interaction domain 148 312 9.1E-66 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CDC59_RS03320 38dc72ff7331b83196b179c7bfda1fe6 558 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 232 247 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CDC59_RS07255 2c66ebc513961448b714bcc7afba4bb3 350 Gene3D G3DSA:3.30.2350.10 112 341 1.8E-67 T 29-03-2018 CDC59_RS07255 2c66ebc513961448b714bcc7afba4bb3 350 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 37 338 6.7E-83 T 29-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDC59_RS07255 2c66ebc513961448b714bcc7afba4bb3 350 Pfam PF01479 S4 domain 41 87 1.4E-7 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CDC59_RS07255 2c66ebc513961448b714bcc7afba4bb3 350 Gene3D G3DSA:3.10.290.10 27 99 1.1E-11 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CDC59_RS07255 2c66ebc513961448b714bcc7afba4bb3 350 SUPERFAMILY SSF55120 111 338 4.64E-66 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDC59_RS07255 2c66ebc513961448b714bcc7afba4bb3 350 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 160 174 - T 29-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDC59_RS07255 2c66ebc513961448b714bcc7afba4bb3 350 SUPERFAMILY SSF55174 40 91 9.13E-8 T 29-03-2018 CDC59_RS07255 2c66ebc513961448b714bcc7afba4bb3 350 Pfam PF00849 RNA pseudouridylate synthase 121 270 2.1E-31 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDC59_RS07255 2c66ebc513961448b714bcc7afba4bb3 350 SMART SM00363 41 100 2.3E-6 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CDC59_RS06680 eb1930ebf8d3d84c548a388b88d2d5e8 594 Gene3D G3DSA:1.20.140.10 277 464 3.5E-46 T 29-03-2018 CDC59_RS06680 eb1930ebf8d3d84c548a388b88d2d5e8 594 SUPERFAMILY SSF47203 281 454 4.51E-46 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CDC59_RS06680 eb1930ebf8d3d84c548a388b88d2d5e8 594 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 2 33 1.8E-13 T 29-03-2018 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria CDC59_RS06680 eb1930ebf8d3d84c548a388b88d2d5e8 594 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 36 156 9.5E-15 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CDC59_RS06680 eb1930ebf8d3d84c548a388b88d2d5e8 594 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 161 270 2.2E-14 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CDC59_RS06680 eb1930ebf8d3d84c548a388b88d2d5e8 594 Gene3D G3DSA:1.10.540.10 15 157 3.2E-21 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CDC59_RS06680 eb1930ebf8d3d84c548a388b88d2d5e8 594 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 471 589 1.3E-26 T 29-03-2018 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain CDC59_RS06680 eb1930ebf8d3d84c548a388b88d2d5e8 594 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 283 449 1.8E-28 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CDC59_RS06680 eb1930ebf8d3d84c548a388b88d2d5e8 594 Gene3D G3DSA:2.40.110.10 158 271 1.2E-23 T 29-03-2018 CDC59_RS06680 eb1930ebf8d3d84c548a388b88d2d5e8 594 SUPERFAMILY SSF56645 34 293 1.27E-59 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CDC59_RS11680 4d244bf8fdff1d438838b8fe8d8be01e 295 Hamap MF_01384 Urease accessory protein UreD [ureD]. 18 279 29.003 T 29-03-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 CDC59_RS11680 4d244bf8fdff1d438838b8fe8d8be01e 295 Pfam PF01774 UreD urease accessory protein 60 268 1.3E-47 T 29-03-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 CDC59_RS14965 b58c9d5b2727642167ee59a12a38f6a9 136 Pfam PF00581 Rhodanese-like domain 22 122 2.8E-15 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS14965 b58c9d5b2727642167ee59a12a38f6a9 136 SMART SM00450 21 125 3.5E-16 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS14965 b58c9d5b2727642167ee59a12a38f6a9 136 Gene3D G3DSA:3.40.250.10 2 134 3.4E-26 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS14965 b58c9d5b2727642167ee59a12a38f6a9 136 SUPERFAMILY SSF52821 6 129 8.77E-29 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS12385 5dc426ed12d07cd825ed412c456d205e 238 Pfam PF04402 Protein of unknown function (DUF541) 39 231 1.2E-25 T 29-03-2018 IPR007497 Protein of unknown function DUF541 CDC59_RS16545 dead7fbaa039f75e4ab31e013a3f69bb 561 Pfam PF00437 Type II/IV secretion system protein 182 452 4.6E-75 T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CDC59_RS16545 dead7fbaa039f75e4ab31e013a3f69bb 561 Gene3D G3DSA:3.40.50.300 286 561 1.8E-60 T 29-03-2018 CDC59_RS16545 dead7fbaa039f75e4ab31e013a3f69bb 561 SUPERFAMILY SSF160246 8 133 2.33E-6 T 29-03-2018 CDC59_RS16545 dead7fbaa039f75e4ab31e013a3f69bb 561 SUPERFAMILY SSF52540 170 560 3.69E-93 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS16545 dead7fbaa039f75e4ab31e013a3f69bb 561 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 380 394 - T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CDC59_RS16545 dead7fbaa039f75e4ab31e013a3f69bb 561 Gene3D G3DSA:3.30.450.90 143 280 8.4E-41 T 29-03-2018 CDC59_RS06125 9532f0e95eac3533c5c09312dbd86bb6 636 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 5 625 46.474 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CDC59_RS06125 9532f0e95eac3533c5c09312dbd86bb6 636 SUPERFAMILY SSF52518 317 502 5.15E-60 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CDC59_RS06125 9532f0e95eac3533c5c09312dbd86bb6 636 Gene3D G3DSA:3.40.50.920 495 626 1.0E-35 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CDC59_RS06125 9532f0e95eac3533c5c09312dbd86bb6 636 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 7 623 2.9E-261 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CDC59_RS06125 9532f0e95eac3533c5c09312dbd86bb6 636 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 6 282 7.1E-118 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CDC59_RS06125 9532f0e95eac3533c5c09312dbd86bb6 636 ProSitePatterns PS00801 Transketolase signature 1. 31 50 - T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CDC59_RS06125 9532f0e95eac3533c5c09312dbd86bb6 636 SUPERFAMILY SSF52922 491 624 1.57E-32 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CDC59_RS06125 9532f0e95eac3533c5c09312dbd86bb6 636 ProSitePatterns PS00802 Transketolase signature 2. 425 441 - T 29-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CDC59_RS06125 9532f0e95eac3533c5c09312dbd86bb6 636 Gene3D G3DSA:3.40.50.970 298 486 6.1E-65 T 29-03-2018 CDC59_RS06125 9532f0e95eac3533c5c09312dbd86bb6 636 SMART SM00861 319 483 2.7E-70 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CDC59_RS06125 9532f0e95eac3533c5c09312dbd86bb6 636 Pfam PF02779 Transketolase, pyrimidine binding domain 318 479 2.0E-40 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CDC59_RS06125 9532f0e95eac3533c5c09312dbd86bb6 636 SUPERFAMILY SSF52518 239 381 3.48E-83 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CDC59_RS06125 9532f0e95eac3533c5c09312dbd86bb6 636 SUPERFAMILY SSF52518 3 195 3.48E-83 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CDC59_RS06125 9532f0e95eac3533c5c09312dbd86bb6 636 Gene3D G3DSA:3.40.50.970 1 297 3.5E-84 T 29-03-2018 CDC59_RS06125 9532f0e95eac3533c5c09312dbd86bb6 636 Pfam PF02780 Transketolase, C-terminal domain 506 616 7.5E-26 T 29-03-2018 IPR033248 Transketolase, C-terminal domain CDC59_RS03610 5601cdb48a9deb5f65db73e36053bce2 373 SMART SM00387 259 373 2.1E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS03610 5601cdb48a9deb5f65db73e36053bce2 373 Gene3D G3DSA:1.10.287.130 129 210 1.7E-6 T 29-03-2018 CDC59_RS03610 5601cdb48a9deb5f65db73e36053bce2 373 SUPERFAMILY SSF47384 130 208 1.2E-7 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS03610 5601cdb48a9deb5f65db73e36053bce2 373 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 265 373 5.8E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS03610 5601cdb48a9deb5f65db73e36053bce2 373 SUPERFAMILY SSF55874 225 373 4.06E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS03610 5601cdb48a9deb5f65db73e36053bce2 373 Gene3D G3DSA:3.40.50.2300 3 128 4.3E-24 T 29-03-2018 CDC59_RS03610 5601cdb48a9deb5f65db73e36053bce2 373 SMART SM00388 141 214 1.3E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS03610 5601cdb48a9deb5f65db73e36053bce2 373 SUPERFAMILY SSF52172 8 134 1.08E-26 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS03610 5601cdb48a9deb5f65db73e36053bce2 373 Pfam PF00512 His Kinase A (phospho-acceptor) domain 144 206 2.9E-6 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS03610 5601cdb48a9deb5f65db73e36053bce2 373 SMART SM00448 9 122 1.3E-16 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS03610 5601cdb48a9deb5f65db73e36053bce2 373 PRINTS PR00344 Bacterial sensor protein C-terminal signature 305 319 1.6E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS03610 5601cdb48a9deb5f65db73e36053bce2 373 PRINTS PR00344 Bacterial sensor protein C-terminal signature 336 354 1.6E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS03610 5601cdb48a9deb5f65db73e36053bce2 373 PRINTS PR00344 Bacterial sensor protein C-terminal signature 360 373 1.6E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS03610 5601cdb48a9deb5f65db73e36053bce2 373 Gene3D G3DSA:3.30.565.10 223 373 1.8E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS03610 5601cdb48a9deb5f65db73e36053bce2 373 Pfam PF00072 Response regulator receiver domain 11 121 1.6E-15 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS18645 e63951d074623cb215d593242de404a1 465 SMART SM00388 246 312 3.9E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS18645 e63951d074623cb215d593242de404a1 465 SUPERFAMILY SSF47384 229 311 4.9E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS18645 e63951d074623cb215d593242de404a1 465 Gene3D G3DSA:3.30.565.10 316 465 1.5E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS18645 e63951d074623cb215d593242de404a1 465 SMART SM00304 192 245 5.5E-5 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CDC59_RS18645 e63951d074623cb215d593242de404a1 465 PRINTS PR00344 Bacterial sensor protein C-terminal signature 451 464 3.3E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS18645 e63951d074623cb215d593242de404a1 465 PRINTS PR00344 Bacterial sensor protein C-terminal signature 392 406 3.3E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS18645 e63951d074623cb215d593242de404a1 465 PRINTS PR00344 Bacterial sensor protein C-terminal signature 410 420 3.3E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS18645 e63951d074623cb215d593242de404a1 465 PRINTS PR00344 Bacterial sensor protein C-terminal signature 427 445 3.3E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS18645 e63951d074623cb215d593242de404a1 465 SUPERFAMILY SSF55874 301 464 2.75E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS18645 e63951d074623cb215d593242de404a1 465 Pfam PF00512 His Kinase A (phospho-acceptor) domain 247 311 2.0E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS18645 e63951d074623cb215d593242de404a1 465 Gene3D G3DSA:1.10.287.130 236 308 2.1E-11 T 29-03-2018 CDC59_RS18645 e63951d074623cb215d593242de404a1 465 TIGRFAM TIGR01386 cztS_silS_copS: heavy metal sensor kinase 5 464 3.4E-141 T 29-03-2018 IPR006290 Heavy metal sensor kinase GO:0000160|GO:0004673|GO:0016020 CDC59_RS18645 e63951d074623cb215d593242de404a1 465 SMART SM00387 355 465 4.8E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS18645 e63951d074623cb215d593242de404a1 465 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 358 464 2.6E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS01940 b2d14e18713cbfc3b2fb7efe51e964ce 760 Gene3D G3DSA:3.30.70.100 626 724 1.6E-9 T 29-03-2018 CDC59_RS01940 b2d14e18713cbfc3b2fb7efe51e964ce 760 SUPERFAMILY SSF50182 562 624 1.63E-9 T 29-03-2018 IPR010920 LSM domain CDC59_RS01940 b2d14e18713cbfc3b2fb7efe51e964ce 760 Gene3D G3DSA:2.30.30.60 578 625 1.9E-7 T 29-03-2018 CDC59_RS01940 b2d14e18713cbfc3b2fb7efe51e964ce 760 SUPERFAMILY SSF82861 480 560 3.66E-13 T 29-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 CDC59_RS01940 b2d14e18713cbfc3b2fb7efe51e964ce 760 SUPERFAMILY SSF82689 625 726 5.89E-12 T 29-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 CDC59_RS01940 b2d14e18713cbfc3b2fb7efe51e964ce 760 Pfam PF00924 Mechanosensitive ion channel 521 658 6.3E-34 T 29-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 CDC59_RS07650 04f222dda4524144826e71ce8ea6cb91 493 SUPERFAMILY SSF56059 339 484 5.96E-66 T 29-03-2018 CDC59_RS07650 04f222dda4524144826e71ce8ea6cb91 493 SUPERFAMILY SSF56059 32 232 5.96E-66 T 29-03-2018 CDC59_RS07650 04f222dda4524144826e71ce8ea6cb91 493 Pfam PF04174 A circularly permuted ATPgrasp 94 425 5.4E-168 T 29-03-2018 IPR007302 Circularly permuted ATPgrasp domain CDC59_RS07650 04f222dda4524144826e71ce8ea6cb91 493 Gene3D G3DSA:3.30.470.20 358 484 1.7E-6 T 29-03-2018 CDC59_RS07650 04f222dda4524144826e71ce8ea6cb91 493 PIRSF PIRSF005522 1 493 1.0E-239 T 29-03-2018 IPR016450 Uncharacterised conserved protein UCP005522 CDC59_RS21820 b2a92b9b5c62c2736ab39196d9bc725d 311 Pfam PF00294 pfkB family carbohydrate kinase 1 293 1.5E-55 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB CDC59_RS21820 b2a92b9b5c62c2736ab39196d9bc725d 311 SUPERFAMILY SSF53613 1 299 2.18E-77 T 29-03-2018 IPR029056 Ribokinase-like CDC59_RS21820 b2a92b9b5c62c2736ab39196d9bc725d 311 Gene3D G3DSA:3.40.1190.20 1 305 1.6E-60 T 29-03-2018 IPR029056 Ribokinase-like CDC59_RS03255 8966c00855d775cb6fe777724d8e86a7 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 4.2E-36 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CDC59_RS03255 8966c00855d775cb6fe777724d8e86a7 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 4.2E-36 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CDC59_RS03255 8966c00855d775cb6fe777724d8e86a7 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 211 226 4.2E-36 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CDC59_RS03255 8966c00855d775cb6fe777724d8e86a7 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 228 246 4.2E-36 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CDC59_RS03255 8966c00855d775cb6fe777724d8e86a7 366 Gene3D G3DSA:3.40.50.300 159 345 2.2E-35 T 29-03-2018 CDC59_RS03255 8966c00855d775cb6fe777724d8e86a7 366 Pfam PF01018 GTP1/OBG 4 158 5.3E-58 T 29-03-2018 IPR006169 GTP1/OBG domain CDC59_RS03255 8966c00855d775cb6fe777724d8e86a7 366 ProSitePatterns PS00905 GTP1/OBG family signature. 213 226 - T 29-03-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 CDC59_RS03255 8966c00855d775cb6fe777724d8e86a7 366 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 3 333 5.2E-142 T 29-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 CDC59_RS03255 8966c00855d775cb6fe777724d8e86a7 366 Pfam PF01926 50S ribosome-binding GTPase 161 285 2.0E-25 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CDC59_RS03255 8966c00855d775cb6fe777724d8e86a7 366 Hamap MF_01454 GTPase Obg [obg]. 2 334 47.371 T 29-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 CDC59_RS03255 8966c00855d775cb6fe777724d8e86a7 366 PIRSF PIRSF002401 1 361 5.9E-134 T 29-03-2018 IPR035101 GTP-binding protein, Obg-type CDC59_RS03255 8966c00855d775cb6fe777724d8e86a7 366 Gene3D G3DSA:2.70.210.12 2 156 2.5E-54 T 29-03-2018 IPR006169 GTP1/OBG domain CDC59_RS03255 8966c00855d775cb6fe777724d8e86a7 366 SUPERFAMILY SSF52540 151 341 3.78E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS03255 8966c00855d775cb6fe777724d8e86a7 366 SUPERFAMILY SSF82051 2 158 5.49E-56 T 29-03-2018 IPR006169 GTP1/OBG domain CDC59_RS02160 1be17d19835d5318fea63fca4b1d904b 1368 Pfam PF04561 RNA polymerase Rpb2, domain 2 349 458 2.1E-15 T 29-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDC59_RS02160 1be17d19835d5318fea63fca4b1d904b 1368 Pfam PF04561 RNA polymerase Rpb2, domain 2 154 226 9.3E-6 T 29-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDC59_RS02160 1be17d19835d5318fea63fca4b1d904b 1368 ProSitePatterns PS01166 RNA polymerases beta chain signature. 1082 1094 - T 29-03-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDC59_RS02160 1be17d19835d5318fea63fca4b1d904b 1368 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 8 1364 0.0 T 29-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDC59_RS02160 1be17d19835d5318fea63fca4b1d904b 1368 Gene3D G3DSA:2.40.50.150 835 1064 1.8E-53 T 29-03-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDC59_RS02160 1be17d19835d5318fea63fca4b1d904b 1368 Gene3D G3DSA:3.90.1100.10 406 649 1.8E-80 T 29-03-2018 CDC59_RS02160 1be17d19835d5318fea63fca4b1d904b 1368 Gene3D G3DSA:3.90.1100.10 19 247 9.1E-45 T 29-03-2018 CDC59_RS02160 1be17d19835d5318fea63fca4b1d904b 1368 Gene3D G3DSA:3.90.1100.10 650 719 2.2E-14 T 29-03-2018 CDC59_RS02160 1be17d19835d5318fea63fca4b1d904b 1368 Pfam PF00562 RNA polymerase Rpb2, domain 6 724 1290 4.5E-159 T 29-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDC59_RS02160 1be17d19835d5318fea63fca4b1d904b 1368 Pfam PF04560 RNA polymerase Rpb2, domain 7 1292 1366 1.6E-26 T 29-03-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDC59_RS02160 1be17d19835d5318fea63fca4b1d904b 1368 Gene3D G3DSA:2.40.270.10 1065 1268 1.1E-79 T 29-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDC59_RS02160 1be17d19835d5318fea63fca4b1d904b 1368 Gene3D G3DSA:3.90.1800.10 1293 1337 9.0E-12 T 29-03-2018 CDC59_RS02160 1be17d19835d5318fea63fca4b1d904b 1368 SUPERFAMILY SSF64484 347 945 0.0 T 29-03-2018 CDC59_RS02160 1be17d19835d5318fea63fca4b1d904b 1368 SUPERFAMILY SSF64484 1058 1366 0.0 T 29-03-2018 CDC59_RS02160 1be17d19835d5318fea63fca4b1d904b 1368 SUPERFAMILY SSF64484 12 229 0.0 T 29-03-2018 CDC59_RS02160 1be17d19835d5318fea63fca4b1d904b 1368 Pfam PF10385 RNA polymerase beta subunit external 1 domain 595 662 4.8E-22 T 29-03-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDC59_RS02160 1be17d19835d5318fea63fca4b1d904b 1368 Gene3D G3DSA:2.40.50.100 721 801 1.5E-27 T 29-03-2018 CDC59_RS02160 1be17d19835d5318fea63fca4b1d904b 1368 Pfam PF04563 RNA polymerase beta subunit 27 504 1.9E-35 T 29-03-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDC59_RS02160 1be17d19835d5318fea63fca4b1d904b 1368 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 13 1368 12.245 T 29-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDC59_RS02160 1be17d19835d5318fea63fca4b1d904b 1368 Pfam PF04565 RNA polymerase Rpb2, domain 3 517 584 2.4E-31 T 29-03-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDC59_RS09550 4b4d952ab1b10fd47a36d7176c65e6f9 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.5E-24 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS09550 4b4d952ab1b10fd47a36d7176c65e6f9 303 Pfam PF03466 LysR substrate binding domain 87 285 1.4E-37 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS09550 4b4d952ab1b10fd47a36d7176c65e6f9 303 SUPERFAMILY SSF46785 1 85 1.9E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS09550 4b4d952ab1b10fd47a36d7176c65e6f9 303 Gene3D G3DSA:3.40.190.10 176 267 5.0E-21 T 29-03-2018 CDC59_RS09550 4b4d952ab1b10fd47a36d7176c65e6f9 303 SUPERFAMILY SSF53850 87 284 7.33E-33 T 29-03-2018 CDC59_RS09550 4b4d952ab1b10fd47a36d7176c65e6f9 303 Gene3D G3DSA:3.40.190.10 87 175 7.7E-21 T 29-03-2018 CDC59_RS09550 4b4d952ab1b10fd47a36d7176c65e6f9 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.3E-11 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS09550 4b4d952ab1b10fd47a36d7176c65e6f9 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.3E-11 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS09550 4b4d952ab1b10fd47a36d7176c65e6f9 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.3E-11 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS09550 4b4d952ab1b10fd47a36d7176c65e6f9 303 Gene3D G3DSA:1.10.10.10 1 86 1.2E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS04935 72e2dbd05af77a24269885910d0b336f 300 Gene3D G3DSA:3.40.50.720 13 300 3.8E-52 T 29-03-2018 CDC59_RS04935 72e2dbd05af77a24269885910d0b336f 300 SUPERFAMILY SSF69572 16 207 8.37E-58 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CDC59_RS04935 72e2dbd05af77a24269885910d0b336f 300 SUPERFAMILY SSF69572 256 298 8.37E-58 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CDC59_RS04935 72e2dbd05af77a24269885910d0b336f 300 Pfam PF00899 ThiF family 30 296 1.6E-35 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CDC59_RS04700 cdd38ae483ed5ea23325829671629349 328 Pfam PF16074 Type IV Pilus-assembly protein W 179 319 2.4E-28 T 29-03-2018 IPR032092 Type IV Pilus-assembly protein W GO:0043683 CDC59_RS04700 cdd38ae483ed5ea23325829671629349 328 Pfam PF07963 Prokaryotic N-terminal methylation motif 10 34 1.5E-7 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS04700 cdd38ae483ed5ea23325829671629349 328 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 13 34 6.5E-5 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS04700 cdd38ae483ed5ea23325829671629349 328 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 13 33 - T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS19350 c57fd2520a8fb4260278c1f0fd53ba5b 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 2.1E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS19350 c57fd2520a8fb4260278c1f0fd53ba5b 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 2.1E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS19350 c57fd2520a8fb4260278c1f0fd53ba5b 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 2.1E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS19350 c57fd2520a8fb4260278c1f0fd53ba5b 304 Gene3D G3DSA:3.40.190.10 181 265 3.1E-9 T 29-03-2018 CDC59_RS19350 c57fd2520a8fb4260278c1f0fd53ba5b 304 Gene3D G3DSA:3.40.190.10 89 180 6.7E-23 T 29-03-2018 CDC59_RS19350 c57fd2520a8fb4260278c1f0fd53ba5b 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 6.0E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS19350 c57fd2520a8fb4260278c1f0fd53ba5b 304 Gene3D G3DSA:1.10.10.10 1 87 9.1E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS19350 c57fd2520a8fb4260278c1f0fd53ba5b 304 SUPERFAMILY SSF46785 1 112 6.67E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS19350 c57fd2520a8fb4260278c1f0fd53ba5b 304 Pfam PF03466 LysR substrate binding domain 88 290 3.7E-35 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS19350 c57fd2520a8fb4260278c1f0fd53ba5b 304 SUPERFAMILY SSF53850 91 293 3.57E-34 T 29-03-2018 CDC59_RS13590 d674baccb3f09ad377ffe87d363941a9 298 SUPERFAMILY SSF54631 63 197 1.64E-29 T 29-03-2018 CDC59_RS13590 d674baccb3f09ad377ffe87d363941a9 298 Gene3D G3DSA:3.30.465.10 195 280 9.4E-25 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CDC59_RS13590 d674baccb3f09ad377ffe87d363941a9 298 SMART SM01091 202 280 2.5E-25 T 29-03-2018 IPR005170 Transporter-associated domain CDC59_RS13590 d674baccb3f09ad377ffe87d363941a9 298 Pfam PF03471 Transporter associated domain 205 278 4.5E-19 T 29-03-2018 IPR005170 Transporter-associated domain CDC59_RS13590 d674baccb3f09ad377ffe87d363941a9 298 Gene3D G3DSA:3.10.580.10 48 194 9.3E-30 T 29-03-2018 CDC59_RS13590 d674baccb3f09ad377ffe87d363941a9 298 Pfam PF00571 CBS domain 82 123 0.006 T 29-03-2018 IPR000644 CBS domain CDC59_RS13590 d674baccb3f09ad377ffe87d363941a9 298 Pfam PF00571 CBS domain 131 185 9.5E-6 T 29-03-2018 IPR000644 CBS domain CDC59_RS13590 d674baccb3f09ad377ffe87d363941a9 298 SUPERFAMILY SSF56176 200 284 7.09E-21 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CDC59_RS10915 45a0d42f54c9bfa34049b04b77edabdb 294 Gene3D G3DSA:1.10.3720.10 17 288 3.8E-32 T 29-03-2018 CDC59_RS10915 45a0d42f54c9bfa34049b04b77edabdb 294 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 29 292 3.0E-78 T 29-03-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 CDC59_RS10915 45a0d42f54c9bfa34049b04b77edabdb 294 SUPERFAMILY SSF161098 43 286 3.53E-29 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS10915 45a0d42f54c9bfa34049b04b77edabdb 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 291 4.8E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS07025 9ee5b13b5328715868fef7145d937af7 252 PIRSF PIRSF030959 1 252 1.0E-106 T 29-03-2018 IPR014562 Uncharacterised conserved protein UCP030959, divergent TPR repeat-containing CDC59_RS07025 9ee5b13b5328715868fef7145d937af7 252 Pfam PF14559 Tetratricopeptide repeat 99 157 1.5E-8 T 29-03-2018 CDC59_RS07025 9ee5b13b5328715868fef7145d937af7 252 Gene3D G3DSA:1.25.40.10 54 250 2.9E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS02300 81a4f912984300513f8a75b24564c0a6 101 SUPERFAMILY SSF57716 2 101 1.28E-37 T 29-03-2018 CDC59_RS02300 81a4f912984300513f8a75b24564c0a6 101 Gene3D G3DSA:4.10.830.10 1 101 1.8E-34 T 29-03-2018 CDC59_RS02300 81a4f912984300513f8a75b24564c0a6 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 27.835 T 29-03-2018 IPR023036 Ribosomal protein S14, bacterial/plastid CDC59_RS02300 81a4f912984300513f8a75b24564c0a6 101 Pfam PF00253 Ribosomal protein S14p/S29e 47 100 9.9E-26 T 29-03-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS16160 a362d3e7b9f8f2553f5bc904482c1522 195 Pfam PF02630 SCO1/SenC 37 117 1.2E-12 T 29-03-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS16160 a362d3e7b9f8f2553f5bc904482c1522 195 Gene3D G3DSA:3.40.30.10 24 194 1.3E-22 T 29-03-2018 CDC59_RS16160 a362d3e7b9f8f2553f5bc904482c1522 195 SUPERFAMILY SSF52833 39 192 8.47E-33 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS16030 2668458178626ca35c80797a7f0cf345 299 Pfam PF02653 Branched-chain amino acid transport system / permease component 12 263 6.9E-40 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CDC59_RS16030 2668458178626ca35c80797a7f0cf345 299 Gene3D G3DSA:1.10.3470.10 3 267 9.6E-36 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CDC59_RS19625 04b5b92d59d230935c04f07e25e45e43 226 TIGRFAM TIGR03352 VI_chp_3: type VI secretion lipoprotein, VC_A0113 family 31 197 1.5E-34 T 29-03-2018 IPR017734 Type VI secretion system, lipoprotein SciN CDC59_RS19625 04b5b92d59d230935c04f07e25e45e43 226 Pfam PF12790 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 38 195 1.5E-33 T 29-03-2018 IPR017734 Type VI secretion system, lipoprotein SciN CDC59_RS23870 ed0ef095b113a644085f7480dcd256ab 309 Pfam PF00149 Calcineurin-like phosphoesterase 42 230 7.9E-10 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CDC59_RS23870 ed0ef095b113a644085f7480dcd256ab 309 Gene3D G3DSA:3.60.21.10 36 274 3.1E-35 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CDC59_RS23870 ed0ef095b113a644085f7480dcd256ab 309 SUPERFAMILY SSF56300 38 283 2.8E-44 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CDC59_RS21895 ccf449832b9d3ede73fe722e69409a0f 1033 SUPERFAMILY SSF82714 706 784 2.22E-18 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS21895 ccf449832b9d3ede73fe722e69409a0f 1033 Gene3D G3DSA:1.20.1640.10 281 498 4.5E-46 T 29-03-2018 CDC59_RS21895 ccf449832b9d3ede73fe722e69409a0f 1033 Gene3D G3DSA:1.20.1640.10 802 1023 2.8E-34 T 29-03-2018 CDC59_RS21895 ccf449832b9d3ede73fe722e69409a0f 1033 SUPERFAMILY SSF82714 183 266 4.32E-16 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS21895 ccf449832b9d3ede73fe722e69409a0f 1033 SUPERFAMILY SSF82693 556 651 2.88E-16 T 29-03-2018 CDC59_RS21895 ccf449832b9d3ede73fe722e69409a0f 1033 SUPERFAMILY SSF82866 294 490 4.58E-47 T 29-03-2018 CDC59_RS21895 ccf449832b9d3ede73fe722e69409a0f 1033 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 5.0E-81 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS21895 ccf449832b9d3ede73fe722e69409a0f 1033 PRINTS PR00702 Acriflavin resistance protein family signature 606 620 5.0E-81 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS21895 ccf449832b9d3ede73fe722e69409a0f 1033 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 5.0E-81 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS21895 ccf449832b9d3ede73fe722e69409a0f 1033 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 5.0E-81 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS21895 ccf449832b9d3ede73fe722e69409a0f 1033 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 5.0E-81 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS21895 ccf449832b9d3ede73fe722e69409a0f 1033 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 5.0E-81 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS21895 ccf449832b9d3ede73fe722e69409a0f 1033 PRINTS PR00702 Acriflavin resistance protein family signature 543 560 5.0E-81 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS21895 ccf449832b9d3ede73fe722e69409a0f 1033 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 5.0E-81 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS21895 ccf449832b9d3ede73fe722e69409a0f 1033 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 5.0E-81 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS21895 ccf449832b9d3ede73fe722e69409a0f 1033 Gene3D G3DSA:3.30.70.1430 40 142 5.2E-25 T 29-03-2018 CDC59_RS21895 ccf449832b9d3ede73fe722e69409a0f 1033 Pfam PF00873 AcrB/AcrD/AcrF family 4 1009 0.0 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS21895 ccf449832b9d3ede73fe722e69409a0f 1033 SUPERFAMILY SSF82693 136 182 7.32E-22 T 29-03-2018 CDC59_RS21895 ccf449832b9d3ede73fe722e69409a0f 1033 SUPERFAMILY SSF82693 268 324 7.32E-22 T 29-03-2018 CDC59_RS21895 ccf449832b9d3ede73fe722e69409a0f 1033 Gene3D G3DSA:3.30.70.1430 558 653 1.5E-12 T 29-03-2018 CDC59_RS21895 ccf449832b9d3ede73fe722e69409a0f 1033 SUPERFAMILY SSF82693 661 702 1.88E-6 T 29-03-2018 CDC59_RS21895 ccf449832b9d3ede73fe722e69409a0f 1033 SUPERFAMILY SSF82693 789 834 1.88E-6 T 29-03-2018 CDC59_RS21895 ccf449832b9d3ede73fe722e69409a0f 1033 SUPERFAMILY SSF82693 40 134 1.2E-22 T 29-03-2018 CDC59_RS21895 ccf449832b9d3ede73fe722e69409a0f 1033 Gene3D G3DSA:3.30.2090.10 704 786 6.3E-19 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS21895 ccf449832b9d3ede73fe722e69409a0f 1033 SUPERFAMILY SSF82866 812 1010 4.45E-42 T 29-03-2018 CDC59_RS21895 ccf449832b9d3ede73fe722e69409a0f 1033 Gene3D G3DSA:3.30.2090.10 181 269 1.2E-13 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS12520 e2e0149866532d280c7f492477cf4f18 395 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 8 392 40.44 T 29-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 CDC59_RS12520 e2e0149866532d280c7f492477cf4f18 395 SUPERFAMILY SSF53383 7 391 1.65E-111 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS12520 e2e0149866532d280c7f492477cf4f18 395 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 216 253 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CDC59_RS12520 e2e0149866532d280c7f492477cf4f18 395 Gene3D G3DSA:3.90.1150.10 2 162 1.6E-45 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS12520 e2e0149866532d280c7f492477cf4f18 395 Gene3D G3DSA:3.40.640.10 163 284 5.0E-39 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDC59_RS12520 e2e0149866532d280c7f492477cf4f18 395 Pfam PF00202 Aminotransferase class-III 19 389 1.0E-100 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CDC59_RS12520 e2e0149866532d280c7f492477cf4f18 395 Gene3D G3DSA:3.90.1150.10 285 395 6.3E-16 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS12520 e2e0149866532d280c7f492477cf4f18 395 PIRSF PIRSF000521 19 394 1.2E-41 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CDC59_RS07445 4bdc2298c6685b1740e9f55589beec34 783 SMART SM01080 49 325 2.9E-78 T 29-03-2018 IPR007890 CHASE2 CDC59_RS07445 4bdc2298c6685b1740e9f55589beec34 783 Gene3D G3DSA:1.10.287.130 558 605 2.4E-6 T 29-03-2018 CDC59_RS07445 4bdc2298c6685b1740e9f55589beec34 783 SMART SM00387 666 778 3.2E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS07445 4bdc2298c6685b1740e9f55589beec34 783 Pfam PF08448 PAS fold 439 554 7.0E-13 T 29-03-2018 IPR013656 PAS fold-4 CDC59_RS07445 4bdc2298c6685b1740e9f55589beec34 783 Pfam PF05226 CHASE2 domain 34 321 1.5E-53 T 29-03-2018 IPR007890 CHASE2 CDC59_RS07445 4bdc2298c6685b1740e9f55589beec34 783 SUPERFAMILY SSF55785 426 550 1.76E-7 T 29-03-2018 IPR000014 PAS domain CDC59_RS07445 4bdc2298c6685b1740e9f55589beec34 783 PIRSF PIRSF037347 13 781 1.8E-188 T 29-03-2018 IPR017181 Signal transduction histidine kinase, CHASE2 sensor domain-containing, predicted CDC59_RS07445 4bdc2298c6685b1740e9f55589beec34 783 SUPERFAMILY SSF47384 548 623 8.04E-8 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS07445 4bdc2298c6685b1740e9f55589beec34 783 Gene3D G3DSA:3.30.450.20 418 557 7.2E-14 T 29-03-2018 CDC59_RS07445 4bdc2298c6685b1740e9f55589beec34 783 PRINTS PR00344 Bacterial sensor protein C-terminal signature 721 731 1.9E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS07445 4bdc2298c6685b1740e9f55589beec34 783 PRINTS PR00344 Bacterial sensor protein C-terminal signature 762 775 1.9E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS07445 4bdc2298c6685b1740e9f55589beec34 783 PRINTS PR00344 Bacterial sensor protein C-terminal signature 703 717 1.9E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS07445 4bdc2298c6685b1740e9f55589beec34 783 PRINTS PR00344 Bacterial sensor protein C-terminal signature 738 756 1.9E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS07445 4bdc2298c6685b1740e9f55589beec34 783 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 668 776 4.6E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS07445 4bdc2298c6685b1740e9f55589beec34 783 SUPERFAMILY SSF55874 614 778 2.88E-41 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS07445 4bdc2298c6685b1740e9f55589beec34 783 Gene3D G3DSA:3.30.565.10 606 777 1.8E-42 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS09000 2d18f9345fed2d9ed6284b4a6529b5bc 707 SUPERFAMILY SSF52540 353 574 2.15E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS09000 2d18f9345fed2d9ed6284b4a6529b5bc 707 ProSitePatterns PS00211 ABC transporters family signature. 203 217 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS09000 2d18f9345fed2d9ed6284b4a6529b5bc 707 Pfam PF12848 ABC transporter 270 345 1.0E-27 T 29-03-2018 IPR032781 ABC-transporter extension domain CDC59_RS09000 2d18f9345fed2d9ed6284b4a6529b5bc 707 SUPERFAMILY SSF52540 50 145 4.98E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS09000 2d18f9345fed2d9ed6284b4a6529b5bc 707 SUPERFAMILY SSF52540 172 308 4.98E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS09000 2d18f9345fed2d9ed6284b4a6529b5bc 707 ProSitePatterns PS00211 ABC transporters family signature. 492 506 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS09000 2d18f9345fed2d9ed6284b4a6529b5bc 707 Pfam PF00005 ABC transporter 71 231 9.1E-21 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS09000 2d18f9345fed2d9ed6284b4a6529b5bc 707 Pfam PF00005 ABC transporter 389 520 3.5E-21 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS09000 2d18f9345fed2d9ed6284b4a6529b5bc 707 Gene3D G3DSA:3.40.50.300 55 332 1.0E-49 T 29-03-2018 CDC59_RS09000 2d18f9345fed2d9ed6284b4a6529b5bc 707 Gene3D G3DSA:3.40.50.300 362 672 8.0E-47 T 29-03-2018 CDC59_RS09000 2d18f9345fed2d9ed6284b4a6529b5bc 707 Pfam PF16326 ABC transporter C-terminal domain 636 701 7.4E-8 T 29-03-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 CDC59_RS09000 2d18f9345fed2d9ed6284b4a6529b5bc 707 SMART SM00382 79 278 9.6E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS09000 2d18f9345fed2d9ed6284b4a6529b5bc 707 SMART SM00382 398 565 3.0E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS08925 2c8aa4abeb9a5b7f7ad8f3a0f39ffc0a 434 ProSitePatterns PS00161 Isocitrate lyase signature. 185 190 - T 29-03-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 CDC59_RS08925 2c8aa4abeb9a5b7f7ad8f3a0f39ffc0a 434 SUPERFAMILY SSF51621 9 423 6.28E-159 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CDC59_RS08925 2c8aa4abeb9a5b7f7ad8f3a0f39ffc0a 434 Gene3D G3DSA:3.20.20.60 1 406 2.5E-151 T 29-03-2018 CDC59_RS08925 2c8aa4abeb9a5b7f7ad8f3a0f39ffc0a 434 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 8 247 2.2E-106 T 29-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 CDC59_RS08925 2c8aa4abeb9a5b7f7ad8f3a0f39ffc0a 434 PIRSF PIRSF001362 1 426 4.3E-235 T 29-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 CDC59_RS08925 2c8aa4abeb9a5b7f7ad8f3a0f39ffc0a 434 Pfam PF00463 Isocitrate lyase family 248 420 3.1E-44 T 29-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 CDC59_RS08925 2c8aa4abeb9a5b7f7ad8f3a0f39ffc0a 434 Pfam PF00463 Isocitrate lyase family 7 247 1.4E-59 T 29-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 CDC59_RS12660 c18400c465f99c7a1611e478dc753c4e 350 Gene3D G3DSA:3.20.20.30 13 335 2.3E-66 T 29-03-2018 CDC59_RS12660 c18400c465f99c7a1611e478dc753c4e 350 SUPERFAMILY SSF51679 8 332 4.97E-71 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CDC59_RS12660 c18400c465f99c7a1611e478dc753c4e 350 Pfam PF00296 Luciferase-like monooxygenase 22 305 2.3E-31 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CDC59_RS12660 c18400c465f99c7a1611e478dc753c4e 350 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 9 333 3.4E-117 T 29-03-2018 IPR019949 Luciferase family oxidoreductase, group 1 CDC59_RS18925 19f2bf1a92a78da671a532b721a77d2c 761 SUPERFAMILY SSF49384 629 737 5.5E-10 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 CDC59_RS18925 19f2bf1a92a78da671a532b721a77d2c 761 Pfam PF00963 Cohesin domain 635 739 1.3E-4 T 29-03-2018 IPR002102 Cellulosome anchoring protein, cohesin domain GO:0000272|GO:0030246 CDC59_RS18925 19f2bf1a92a78da671a532b721a77d2c 761 SMART SM00965 207 258 8.3E-5 T 29-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 CDC59_RS18925 19f2bf1a92a78da671a532b721a77d2c 761 Gene3D G3DSA:1.25.40.10 118 332 0.13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS18925 19f2bf1a92a78da671a532b721a77d2c 761 Pfam PF00263 Bacterial type II and III secretion system protein 399 558 1.6E-43 T 29-03-2018 IPR004846 Type II/III secretion system GO:0009306 CDC59_RS18925 19f2bf1a92a78da671a532b721a77d2c 761 PRINTS PR00811 Bacterial general secretion pathway protein D signature 331 341 2.3E-11 T 29-03-2018 IPR001775 GspD/PilQ family CDC59_RS18925 19f2bf1a92a78da671a532b721a77d2c 761 PRINTS PR00811 Bacterial general secretion pathway protein D signature 390 414 2.3E-11 T 29-03-2018 IPR001775 GspD/PilQ family CDC59_RS18925 19f2bf1a92a78da671a532b721a77d2c 761 PRINTS PR00811 Bacterial general secretion pathway protein D signature 522 540 2.3E-11 T 29-03-2018 IPR001775 GspD/PilQ family CDC59_RS18925 19f2bf1a92a78da671a532b721a77d2c 761 PRINTS PR00811 Bacterial general secretion pathway protein D signature 545 559 2.3E-11 T 29-03-2018 IPR001775 GspD/PilQ family CDC59_RS18925 19f2bf1a92a78da671a532b721a77d2c 761 PRINTS PR00811 Bacterial general secretion pathway protein D signature 425 435 2.3E-11 T 29-03-2018 IPR001775 GspD/PilQ family CDC59_RS18925 19f2bf1a92a78da671a532b721a77d2c 761 Pfam PF07660 Secretin and TonB N terminus short domain 207 257 1.5E-8 T 29-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 CDC59_RS18925 19f2bf1a92a78da671a532b721a77d2c 761 Gene3D G3DSA:2.60.40.680 627 756 5.8E-12 T 29-03-2018 CDC59_RS18925 19f2bf1a92a78da671a532b721a77d2c 761 Gene3D G3DSA:1.25.40.10 10 117 0.0012 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS23145 9621e0fec69f77fe7e1e27fcc4d456da 385 Pfam PF13458 Periplasmic binding protein 36 374 3.3E-62 T 29-03-2018 IPR028081 Leucine-binding protein domain CDC59_RS23145 9621e0fec69f77fe7e1e27fcc4d456da 385 SUPERFAMILY SSF53822 36 384 1.33E-71 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CDC59_RS23145 9621e0fec69f77fe7e1e27fcc4d456da 385 Gene3D G3DSA:3.40.50.2300 231 373 3.5E-18 T 29-03-2018 CDC59_RS23145 9621e0fec69f77fe7e1e27fcc4d456da 385 Gene3D G3DSA:3.40.50.2300 31 230 1.4E-35 T 29-03-2018 CDC59_RS15485 1310f460dddac48465df975143a74788 396 Gene3D G3DSA:3.30.300.10 12 128 1.5E-43 T 29-03-2018 CDC59_RS15485 1310f460dddac48465df975143a74788 396 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 5 102 2.5E-40 T 29-03-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CDC59_RS15485 1310f460dddac48465df975143a74788 396 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 6 383 5.6E-182 T 29-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CDC59_RS15485 1310f460dddac48465df975143a74788 396 SUPERFAMILY SSF55973 113 234 5.89E-52 T 29-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CDC59_RS15485 1310f460dddac48465df975143a74788 396 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 261 269 - T 29-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CDC59_RS15485 1310f460dddac48465df975143a74788 396 Gene3D G3DSA:3.30.300.10 248 387 1.5E-48 T 29-03-2018 CDC59_RS15485 1310f460dddac48465df975143a74788 396 SUPERFAMILY SSF55973 4 110 3.18E-45 T 29-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CDC59_RS15485 1310f460dddac48465df975143a74788 396 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 3 385 56.369 T 29-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CDC59_RS15485 1310f460dddac48465df975143a74788 396 Gene3D G3DSA:3.30.300.10 129 235 2.3E-45 T 29-03-2018 CDC59_RS15485 1310f460dddac48465df975143a74788 396 Pfam PF02772 S-adenosylmethionine synthetase, central domain 118 233 3.0E-47 T 29-03-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CDC59_RS15485 1310f460dddac48465df975143a74788 396 PIRSF PIRSF000497 1 385 1.6E-171 T 29-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CDC59_RS15485 1310f460dddac48465df975143a74788 396 SUPERFAMILY SSF55973 235 386 1.15E-67 T 29-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CDC59_RS15485 1310f460dddac48465df975143a74788 396 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 235 373 7.2E-68 T 29-03-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CDC59_RS15485 1310f460dddac48465df975143a74788 396 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 119 129 - T 29-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CDC59_RS04470 8840dcfd4cb6d818f67f5f36a4d8e148 305 SUPERFAMILY SSF51735 10 303 4.11E-95 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS04470 8840dcfd4cb6d818f67f5f36a4d8e148 305 Gene3D G3DSA:3.90.25.10 205 290 2.3E-20 T 29-03-2018 CDC59_RS04470 8840dcfd4cb6d818f67f5f36a4d8e148 305 Gene3D G3DSA:3.90.25.10 170 204 3.0E-6 T 29-03-2018 CDC59_RS04470 8840dcfd4cb6d818f67f5f36a4d8e148 305 Pfam PF04321 RmlD substrate binding domain 10 302 5.4E-105 T 29-03-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 CDC59_RS04470 8840dcfd4cb6d818f67f5f36a4d8e148 305 Gene3D G3DSA:3.40.50.720 8 169 5.0E-21 T 29-03-2018 CDC59_RS04470 8840dcfd4cb6d818f67f5f36a4d8e148 305 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 10 302 1.2E-100 T 29-03-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 CDC59_RS09095 30173a8653a750f44394ada357a8d343 403 TIGRFAM TIGR03538 DapC_gpp: succinyldiaminopimelate transaminase 5 400 3.0E-185 T 29-03-2018 IPR019878 Succinyldiaminopimelate transaminase, DapC, beta/gammaproteobacteria GO:0009016|GO:0009089 CDC59_RS09095 30173a8653a750f44394ada357a8d343 403 SUPERFAMILY SSF53383 5 401 1.01E-87 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS09095 30173a8653a750f44394ada357a8d343 403 Gene3D G3DSA:3.40.640.10 50 305 3.1E-45 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDC59_RS09095 30173a8653a750f44394ada357a8d343 403 Pfam PF00155 Aminotransferase class I and II 36 388 7.0E-45 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CDC59_RS09095 30173a8653a750f44394ada357a8d343 403 Gene3D G3DSA:3.90.1150.10 306 403 2.5E-16 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS13770 b48a38b26e18aeda87d1c4af3433d364 386 Gene3D G3DSA:3.30.420.40 13 201 2.7E-52 T 29-03-2018 CDC59_RS13770 b48a38b26e18aeda87d1c4af3433d364 386 Gene3D G3DSA:3.30.420.40 236 386 3.8E-25 T 29-03-2018 CDC59_RS13770 b48a38b26e18aeda87d1c4af3433d364 386 Pfam PF03702 Anhydro-N-acetylmuramic acid kinase 15 386 2.3E-135 T 29-03-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 CDC59_RS13770 b48a38b26e18aeda87d1c4af3433d364 386 SUPERFAMILY SSF53067 76 121 1.86E-23 T 29-03-2018 CDC59_RS13770 b48a38b26e18aeda87d1c4af3433d364 386 SUPERFAMILY SSF53067 155 358 1.86E-23 T 29-03-2018 CDC59_RS13770 b48a38b26e18aeda87d1c4af3433d364 386 SUPERFAMILY SSF53067 15 49 1.86E-23 T 29-03-2018 CDC59_RS13770 b48a38b26e18aeda87d1c4af3433d364 386 Hamap MF_01270 Anhydro-N-acetylmuramic acid kinase [anmK]. 14 386 40.945 T 29-03-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 CDC59_RS15700 c232103bcdc6ed7bee52d53f6a406ac7 429 Gene3D G3DSA:3.30.460.10 2 143 5.8E-28 T 29-03-2018 CDC59_RS15700 c232103bcdc6ed7bee52d53f6a406ac7 429 PIRSF PIRSF000813 20 429 9.2E-199 T 29-03-2018 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 CDC59_RS15700 c232103bcdc6ed7bee52d53f6a406ac7 429 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 172 234 4.9E-11 T 29-03-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 CDC59_RS15700 c232103bcdc6ed7bee52d53f6a406ac7 429 SUPERFAMILY SSF81891 147 382 2.62E-52 T 29-03-2018 CDC59_RS15700 c232103bcdc6ed7bee52d53f6a406ac7 429 Hamap MF_01261 Multifunctional CCA protein [cca]. 20 429 50.865 T 29-03-2018 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 CDC59_RS15700 c232103bcdc6ed7bee52d53f6a406ac7 429 Pfam PF01743 Poly A polymerase head domain 22 145 8.9E-15 T 29-03-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 CDC59_RS15700 c232103bcdc6ed7bee52d53f6a406ac7 429 Gene3D G3DSA:1.10.3090.10 144 428 2.3E-50 T 29-03-2018 CDC59_RS15700 c232103bcdc6ed7bee52d53f6a406ac7 429 Pfam PF01966 HD domain 254 352 5.3E-8 T 29-03-2018 IPR006674 HD domain CDC59_RS15700 c232103bcdc6ed7bee52d53f6a406ac7 429 SUPERFAMILY SSF81301 17 144 2.4E-28 T 29-03-2018 CDC59_RS08520 35add349f509ca54b0826123461f5ea1 487 Pfam PF12801 4Fe-4S binding domain 101 140 1.6E-10 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CDC59_RS08520 35add349f509ca54b0826123461f5ea1 487 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 276 287 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CDC59_RS08520 35add349f509ca54b0826123461f5ea1 487 Gene3D G3DSA:3.30.70.20 280 294 0.23 T 29-03-2018 CDC59_RS08520 35add349f509ca54b0826123461f5ea1 487 Gene3D G3DSA:1.10.1060.10 309 350 7.0E-4 T 29-03-2018 CDC59_RS08520 35add349f509ca54b0826123461f5ea1 487 Pfam PF13746 4Fe-4S dicluster domain 223 329 5.2E-43 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CDC59_RS08520 35add349f509ca54b0826123461f5ea1 487 Gene3D G3DSA:3.30.70.20 295 308 0.026 T 29-03-2018 CDC59_RS08520 35add349f509ca54b0826123461f5ea1 487 Gene3D G3DSA:3.30.70.20 226 279 8.9E-11 T 29-03-2018 CDC59_RS08520 35add349f509ca54b0826123461f5ea1 487 TIGRFAM TIGR02745 ccoG_rdxA_fixG: cytochrome c oxidase accessory protein CcoG 45 484 8.5E-149 T 29-03-2018 IPR014116 Cytochrome c oxidase cbb3 type, accessory protein FixG GO:0016021|GO:0055114 CDC59_RS08520 35add349f509ca54b0826123461f5ea1 487 Pfam PF11614 IG-like fold at C-terminal of FixG, putative oxidoreductase 364 486 5.6E-30 T 29-03-2018 IPR032879 FixG, C-terminal immunoglobulin-like domain CDC59_RS08520 35add349f509ca54b0826123461f5ea1 487 SUPERFAMILY SSF54862 109 131 5.16E-34 T 29-03-2018 CDC59_RS08520 35add349f509ca54b0826123461f5ea1 487 SUPERFAMILY SSF54862 177 371 5.16E-34 T 29-03-2018 CDC59_RS08520 35add349f509ca54b0826123461f5ea1 487 Gene3D G3DSA:2.60.40.10 364 486 2.8E-28 T 29-03-2018 IPR013783 Immunoglobulin-like fold CDC59_RS22865 92aee8fc2c59586a36fbb9d23e4af27c 230 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 48 222 2.6E-17 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS22865 92aee8fc2c59586a36fbb9d23e4af27c 230 Gene3D G3DSA:1.10.3720.10 15 224 1.2E-33 T 29-03-2018 CDC59_RS22865 92aee8fc2c59586a36fbb9d23e4af27c 230 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 23 117 5.3E-22 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CDC59_RS22865 92aee8fc2c59586a36fbb9d23e4af27c 230 SUPERFAMILY SSF161098 19 214 6.67E-36 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS03665 5b99da016115d7386a5520aef2adaf54 391 SUPERFAMILY SSF111369 170 183 1.57E-8 T 29-03-2018 CDC59_RS03665 5b99da016115d7386a5520aef2adaf54 391 SUPERFAMILY SSF111369 219 313 1.57E-8 T 29-03-2018 CDC59_RS03665 5b99da016115d7386a5520aef2adaf54 391 Gene3D G3DSA:1.10.287.470 141 207 0.0011 T 29-03-2018 CDC59_RS03665 5b99da016115d7386a5520aef2adaf54 391 Gene3D G3DSA:1.20.1600.10 208 336 1.4E-15 T 29-03-2018 CDC59_RS03665 5b99da016115d7386a5520aef2adaf54 391 SUPERFAMILY SSF111369 75 161 8.63E-13 T 29-03-2018 CDC59_RS03665 5b99da016115d7386a5520aef2adaf54 391 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 73 317 3.1E-18 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CDC59_RS03665 5b99da016115d7386a5520aef2adaf54 391 Gene3D G3DSA:2.40.50.100 76 140 5.5E-18 T 29-03-2018 CDC59_RS02260 90970f3cef51e2661290c8169bdf8931 109 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 109 24.766 T 29-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS02260 90970f3cef51e2661290c8169bdf8931 109 ProSitePatterns PS00464 Ribosomal protein L22 signature. 83 107 - T 29-03-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS02260 90970f3cef51e2661290c8169bdf8931 109 Pfam PF00237 Ribosomal protein L22p/L17e 6 107 1.4E-36 T 29-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 CDC59_RS02260 90970f3cef51e2661290c8169bdf8931 109 SUPERFAMILY SSF54843 1 108 1.09E-40 T 29-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 CDC59_RS02260 90970f3cef51e2661290c8169bdf8931 109 Gene3D G3DSA:3.90.470.10 1 109 5.0E-42 T 29-03-2018 CDC59_RS02260 90970f3cef51e2661290c8169bdf8931 109 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 106 4.4E-43 T 29-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS10965 01b57ac57172ed4315f7ea2debbf29a2 1081 SUPERFAMILY SSF52440 561 680 4.6E-50 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CDC59_RS10965 01b57ac57172ed4315f7ea2debbf29a2 1081 SUPERFAMILY SSF52335 944 1079 2.09E-38 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CDC59_RS10965 01b57ac57172ed4315f7ea2debbf29a2 1081 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1077 13.384 T 29-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDC59_RS10965 01b57ac57172ed4315f7ea2debbf29a2 1081 Gene3D G3DSA:3.40.50.20 541 659 7.8E-63 T 29-03-2018 CDC59_RS10965 01b57ac57172ed4315f7ea2debbf29a2 1081 Gene3D G3DSA:3.40.50.20 4 128 3.7E-39 T 29-03-2018 CDC59_RS10965 01b57ac57172ed4315f7ea2debbf29a2 1081 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 171 185 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CDC59_RS10965 01b57ac57172ed4315f7ea2debbf29a2 1081 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 341 7.8E-71 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CDC59_RS10965 01b57ac57172ed4315f7ea2debbf29a2 1081 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 678 884 3.3E-36 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CDC59_RS10965 01b57ac57172ed4315f7ea2debbf29a2 1081 SUPERFAMILY SSF52440 1 127 2.73E-51 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CDC59_RS10965 01b57ac57172ed4315f7ea2debbf29a2 1081 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 175 187 3.9E-66 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDC59_RS10965 01b57ac57172ed4315f7ea2debbf29a2 1081 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 304 333 3.9E-66 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDC59_RS10965 01b57ac57172ed4315f7ea2debbf29a2 1081 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 3.9E-66 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDC59_RS10965 01b57ac57172ed4315f7ea2debbf29a2 1081 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 246 263 3.9E-66 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDC59_RS10965 01b57ac57172ed4315f7ea2debbf29a2 1081 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 3.9E-66 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDC59_RS10965 01b57ac57172ed4315f7ea2debbf29a2 1081 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 211 230 3.9E-66 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDC59_RS10965 01b57ac57172ed4315f7ea2debbf29a2 1081 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 387 405 3.9E-66 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDC59_RS10965 01b57ac57172ed4315f7ea2debbf29a2 1081 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1061 0.0 T 29-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDC59_RS10965 01b57ac57172ed4315f7ea2debbf29a2 1081 SUPERFAMILY SSF56059 128 408 8.31E-107 T 29-03-2018 CDC59_RS10965 01b57ac57172ed4315f7ea2debbf29a2 1081 SUPERFAMILY SSF48108 403 554 1.57E-49 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDC59_RS10965 01b57ac57172ed4315f7ea2debbf29a2 1081 Pfam PF02142 MGS-like domain 965 1051 5.4E-20 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CDC59_RS10965 01b57ac57172ed4315f7ea2debbf29a2 1081 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1072 13.196 T 29-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDC59_RS10965 01b57ac57172ed4315f7ea2debbf29a2 1081 Gene3D G3DSA:3.30.470.20 129 410 4.3E-65 T 29-03-2018 CDC59_RS10965 01b57ac57172ed4315f7ea2debbf29a2 1081 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 304 311 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CDC59_RS10965 01b57ac57172ed4315f7ea2debbf29a2 1081 SMART SM01096 426 549 3.7E-70 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDC59_RS10965 01b57ac57172ed4315f7ea2debbf29a2 1081 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 714 728 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CDC59_RS10965 01b57ac57172ed4315f7ea2debbf29a2 1081 Gene3D G3DSA:3.40.50.1380 936 1064 1.6E-37 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CDC59_RS10965 01b57ac57172ed4315f7ea2debbf29a2 1081 Gene3D G3DSA:3.30.470.20 749 935 3.5E-46 T 29-03-2018 CDC59_RS10965 01b57ac57172ed4315f7ea2debbf29a2 1081 Gene3D G3DSA:3.30.1490.20 660 748 1.4E-23 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CDC59_RS10965 01b57ac57172ed4315f7ea2debbf29a2 1081 Gene3D G3DSA:1.10.1030.10 411 540 1.7E-47 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDC59_RS10965 01b57ac57172ed4315f7ea2debbf29a2 1081 SUPERFAMILY SSF56059 678 942 4.6E-105 T 29-03-2018 CDC59_RS10965 01b57ac57172ed4315f7ea2debbf29a2 1081 SMART SM00851 964 1051 2.1E-29 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CDC59_RS10965 01b57ac57172ed4315f7ea2debbf29a2 1081 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 429 549 2.4E-37 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDC59_RS10965 01b57ac57172ed4315f7ea2debbf29a2 1081 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 847 854 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CDC59_RS04830 0b230f54480d4e287372951061042d29 125 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 12 124 1.5E-20 T 29-03-2018 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III CDC59_RS06595 15cb80e0af977b1e64f8c1989419115c 99 Gene3D G3DSA:3.30.70.1060 1 91 1.6E-7 T 29-03-2018 CDC59_RS06595 15cb80e0af977b1e64f8c1989419115c 99 SUPERFAMILY SSF54909 11 90 6.79E-7 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CDC59_RS22420 6289b2fafe13d4c2f3064108b22d4ded 73 Gene3D G3DSA:2.40.50.140 1 72 1.0E-30 T 29-03-2018 CDC59_RS22420 6289b2fafe13d4c2f3064108b22d4ded 73 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 71 6.2E-29 T 29-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CDC59_RS22420 6289b2fafe13d4c2f3064108b22d4ded 73 Pfam PF01176 Translation initiation factor 1A / IF-1 8 70 1.6E-21 T 29-03-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 CDC59_RS22420 6289b2fafe13d4c2f3064108b22d4ded 73 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 24.485 T 29-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CDC59_RS22420 6289b2fafe13d4c2f3064108b22d4ded 73 SUPERFAMILY SSF50249 1 71 2.66E-23 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDC59_RS18030 210a8e3e26c0148a7bf8f667d435b076 459 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 344 449 1.2E-21 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CDC59_RS18030 210a8e3e26c0148a7bf8f667d435b076 459 Gene3D G3DSA:3.30.390.30 343 458 8.8E-27 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CDC59_RS18030 210a8e3e26c0148a7bf8f667d435b076 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 260 274 2.0E-42 T 29-03-2018 CDC59_RS18030 210a8e3e26c0148a7bf8f667d435b076 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 339 360 2.0E-42 T 29-03-2018 CDC59_RS18030 210a8e3e26c0148a7bf8f667d435b076 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 303 310 2.0E-42 T 29-03-2018 CDC59_RS18030 210a8e3e26c0148a7bf8f667d435b076 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 172 197 2.0E-42 T 29-03-2018 CDC59_RS18030 210a8e3e26c0148a7bf8f667d435b076 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 2.0E-42 T 29-03-2018 CDC59_RS18030 210a8e3e26c0148a7bf8f667d435b076 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 2.0E-42 T 29-03-2018 CDC59_RS18030 210a8e3e26c0148a7bf8f667d435b076 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 426 446 2.0E-42 T 29-03-2018 CDC59_RS18030 210a8e3e26c0148a7bf8f667d435b076 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 404 419 2.0E-42 T 29-03-2018 CDC59_RS18030 210a8e3e26c0148a7bf8f667d435b076 459 Gene3D G3DSA:3.40.50.720 163 336 1.3E-33 T 29-03-2018 CDC59_RS18030 210a8e3e26c0148a7bf8f667d435b076 459 Gene3D G3DSA:3.50.50.60 1 162 1.0E-22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS18030 210a8e3e26c0148a7bf8f667d435b076 459 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 29-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CDC59_RS18030 210a8e3e26c0148a7bf8f667d435b076 459 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 312 3.1E-54 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS18030 210a8e3e26c0148a7bf8f667d435b076 459 PIRSF PIRSF000350 1 442 4.7E-80 T 29-03-2018 CDC59_RS18030 210a8e3e26c0148a7bf8f667d435b076 459 SUPERFAMILY SSF55424 343 455 2.41E-28 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CDC59_RS18030 210a8e3e26c0148a7bf8f667d435b076 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 172 190 1.5E-25 T 29-03-2018 CDC59_RS18030 210a8e3e26c0148a7bf8f667d435b076 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 275 1.5E-25 T 29-03-2018 CDC59_RS18030 210a8e3e26c0148a7bf8f667d435b076 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 288 310 1.5E-25 T 29-03-2018 CDC59_RS18030 210a8e3e26c0148a7bf8f667d435b076 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 133 151 1.5E-25 T 29-03-2018 CDC59_RS18030 210a8e3e26c0148a7bf8f667d435b076 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.5E-25 T 29-03-2018 CDC59_RS18030 210a8e3e26c0148a7bf8f667d435b076 459 SUPERFAMILY SSF51905 1 333 7.77E-54 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS12525 886abe47ceaf655df5bd84a3f033d058 158 Gene3D G3DSA:3.40.630.30 22 145 1.6E-18 T 29-03-2018 CDC59_RS12525 886abe47ceaf655df5bd84a3f033d058 158 Pfam PF13673 Acetyltransferase (GNAT) domain 66 140 9.5E-11 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CDC59_RS12525 886abe47ceaf655df5bd84a3f033d058 158 SUPERFAMILY SSF55729 28 139 8.23E-18 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDC59_RS20950 ff722db841383478eb7cbc5bca1c9f65 995 Gene3D G3DSA:2.30.38.10 362 437 1.3E-22 T 29-03-2018 CDC59_RS20950 ff722db841383478eb7cbc5bca1c9f65 995 ProSitePatterns PS00455 Putative AMP-binding domain signature. 195 206 - T 29-03-2018 IPR020845 AMP-binding, conserved site CDC59_RS20950 ff722db841383478eb7cbc5bca1c9f65 995 Pfam PF00425 chorismate binding enzyme 727 979 5.0E-70 T 29-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal CDC59_RS20950 ff722db841383478eb7cbc5bca1c9f65 995 SUPERFAMILY SSF56801 22 539 9.03E-134 T 29-03-2018 CDC59_RS20950 ff722db841383478eb7cbc5bca1c9f65 995 SUPERFAMILY SSF56322 568 987 1.02E-91 T 29-03-2018 IPR005801 ADC synthase GO:0009058 CDC59_RS20950 ff722db841383478eb7cbc5bca1c9f65 995 Gene3D G3DSA:3.40.50.980 201 361 5.0E-35 T 29-03-2018 CDC59_RS20950 ff722db841383478eb7cbc5bca1c9f65 995 PRINTS PR00095 Anthranilate synthase component I signature 936 950 4.7E-7 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CDC59_RS20950 ff722db841383478eb7cbc5bca1c9f65 995 PRINTS PR00095 Anthranilate synthase component I signature 827 840 4.7E-7 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CDC59_RS20950 ff722db841383478eb7cbc5bca1c9f65 995 PRINTS PR00095 Anthranilate synthase component I signature 921 935 4.7E-7 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CDC59_RS20950 ff722db841383478eb7cbc5bca1c9f65 995 PRINTS PR00095 Anthranilate synthase component I signature 841 854 4.7E-7 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CDC59_RS20950 ff722db841383478eb7cbc5bca1c9f65 995 Pfam PF13193 AMP-binding enzyme C-terminal domain 452 527 5.5E-10 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CDC59_RS20950 ff722db841383478eb7cbc5bca1c9f65 995 Pfam PF00501 AMP-binding enzyme 36 443 1.3E-82 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CDC59_RS20950 ff722db841383478eb7cbc5bca1c9f65 995 Gene3D G3DSA:3.60.120.10 628 995 3.8E-85 T 29-03-2018 IPR005801 ADC synthase GO:0009058 CDC59_RS20950 ff722db841383478eb7cbc5bca1c9f65 995 TIGRFAM TIGR03494 salicyl_syn: salicylate synthase 576 987 5.3E-148 T 29-03-2018 IPR019996 Salicylate synthase GO:0008909|GO:0016833 KEGG: 00130+5.4.4.2|KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6120|MetaCyc: PWY-6406|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CDC59_RS20950 ff722db841383478eb7cbc5bca1c9f65 995 Gene3D G3DSA:3.30.300.30 439 566 7.1E-23 T 29-03-2018 CDC59_RS20950 ff722db841383478eb7cbc5bca1c9f65 995 Gene3D G3DSA:3.40.50.980 27 200 1.1E-29 T 29-03-2018 CDC59_RS17370 f6e7bb99e32f14d5b4e514f34948a5b1 224 SUPERFAMILY SSF53271 5 220 5.48E-41 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CDC59_RS17370 f6e7bb99e32f14d5b4e514f34948a5b1 224 Gene3D G3DSA:3.40.50.2020 3 223 4.6E-30 T 29-03-2018 CDC59_RS17370 f6e7bb99e32f14d5b4e514f34948a5b1 224 Pfam PF00156 Phosphoribosyl transferase domain 10 198 8.1E-21 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CDC59_RS14160 da7573c707ec425db5cc4f02a35af0ca 387 Pfam PF07690 Major Facilitator Superfamily 15 341 4.1E-37 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDC59_RS14160 da7573c707ec425db5cc4f02a35af0ca 387 Gene3D G3DSA:1.20.1250.20 1 194 1.3E-30 T 29-03-2018 CDC59_RS14160 da7573c707ec425db5cc4f02a35af0ca 387 SUPERFAMILY SSF103473 10 382 1.57E-59 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS14160 da7573c707ec425db5cc4f02a35af0ca 387 Gene3D G3DSA:1.20.1250.20 195 387 8.7E-20 T 29-03-2018 CDC59_RS07860 eaa7551c302166b75f778f87147a6b1c 248 Pfam PF06426 Serine acetyltransferase, N-terminal 3 35 1.5E-4 T 29-03-2018 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 CDC59_RS07860 eaa7551c302166b75f778f87147a6b1c 248 SUPERFAMILY SSF51161 3 170 3.88E-52 T 29-03-2018 IPR011004 Trimeric LpxA-like CDC59_RS07860 eaa7551c302166b75f778f87147a6b1c 248 Gene3D G3DSA:1.10.3130.10 1 63 3.6E-25 T 29-03-2018 CDC59_RS07860 eaa7551c302166b75f778f87147a6b1c 248 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 118 152 1.0E-5 T 29-03-2018 IPR001451 Hexapeptide repeat CDC59_RS07860 eaa7551c302166b75f778f87147a6b1c 248 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 72 108 3.3E-6 T 29-03-2018 IPR001451 Hexapeptide repeat CDC59_RS07860 eaa7551c302166b75f778f87147a6b1c 248 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 5 167 1.3E-72 T 29-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 CDC59_RS07860 eaa7551c302166b75f778f87147a6b1c 248 Gene3D G3DSA:2.160.10.10 64 234 2.6E-37 T 29-03-2018 CDC59_RS08875 c5f9502ff6036b2969b62153de8ac5d3 327 Pfam PF03466 LysR substrate binding domain 89 294 4.3E-44 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS08875 c5f9502ff6036b2969b62153de8ac5d3 327 SUPERFAMILY SSF53850 91 298 5.37E-43 T 29-03-2018 CDC59_RS08875 c5f9502ff6036b2969b62153de8ac5d3 327 Gene3D G3DSA:3.40.190.10 181 267 1.2E-17 T 29-03-2018 CDC59_RS08875 c5f9502ff6036b2969b62153de8ac5d3 327 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 9.3E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS08875 c5f9502ff6036b2969b62153de8ac5d3 327 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 9.3E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS08875 c5f9502ff6036b2969b62153de8ac5d3 327 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 9.3E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS08875 c5f9502ff6036b2969b62153de8ac5d3 327 SUPERFAMILY SSF46785 11 112 1.72E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS08875 c5f9502ff6036b2969b62153de8ac5d3 327 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 64 7.7E-15 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS08875 c5f9502ff6036b2969b62153de8ac5d3 327 Gene3D G3DSA:3.40.190.10 89 180 7.8E-24 T 29-03-2018 CDC59_RS08875 c5f9502ff6036b2969b62153de8ac5d3 327 Gene3D G3DSA:1.10.10.10 1 84 7.0E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS23445 9dde85fb3ebce71f07243aae8c1662cb 84 Pfam PF14452 Multiubiquitin 8 81 9.7E-13 T 29-03-2018 IPR027802 Multi-ubiquitin domain CDC59_RS15650 836b0b8577a7b2fea13904249fc156f8 483 Gene3D G3DSA:3.40.720.10 23 483 7.3E-131 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CDC59_RS15650 836b0b8577a7b2fea13904249fc156f8 483 Pfam PF00245 Alkaline phosphatase 43 482 1.0E-102 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CDC59_RS15650 836b0b8577a7b2fea13904249fc156f8 483 SUPERFAMILY SSF53649 38 483 1.31E-126 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CDC59_RS15650 836b0b8577a7b2fea13904249fc156f8 483 PRINTS PR00113 Alkaline phosphatase signature 153 173 1.2E-39 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CDC59_RS15650 836b0b8577a7b2fea13904249fc156f8 483 PRINTS PR00113 Alkaline phosphatase signature 284 313 1.2E-39 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CDC59_RS15650 836b0b8577a7b2fea13904249fc156f8 483 PRINTS PR00113 Alkaline phosphatase signature 42 62 1.2E-39 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CDC59_RS15650 836b0b8577a7b2fea13904249fc156f8 483 PRINTS PR00113 Alkaline phosphatase signature 207 217 1.2E-39 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CDC59_RS15650 836b0b8577a7b2fea13904249fc156f8 483 SMART SM00098 43 482 2.6E-89 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CDC59_RS17015 7b3e0ac7dcacce4971c2989672dbc7ba 218 Pfam PF13861 FlgD Tudor-like domain 83 215 5.6E-15 T 29-03-2018 IPR025963 FlgD Tudor-like domain CDC59_RS17015 7b3e0ac7dcacce4971c2989672dbc7ba 218 Pfam PF13860 FlgD Ig-like domain 100 173 1.1E-22 T 29-03-2018 IPR025965 FlgD Ig-like domain CDC59_RS17015 7b3e0ac7dcacce4971c2989672dbc7ba 218 Pfam PF03963 Flagellar hook capping protein - N-terminal region 5 77 2.1E-22 T 29-03-2018 IPR005648 Flagellar hook capping protein CDC59_RS16490 33467f4c84cad0bcf18e9c2ba60f58f5 352 Gene3D G3DSA:2.120.10.30 159 352 1.3E-18 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CDC59_RS16490 33467f4c84cad0bcf18e9c2ba60f58f5 352 SUPERFAMILY SSF101898 55 305 4.45E-37 T 29-03-2018 CDC59_RS16490 33467f4c84cad0bcf18e9c2ba60f58f5 352 PIRSF PIRSF026412 22 346 1.3E-136 T 29-03-2018 IPR011217 Streptogramin lyase GO:0000287|GO:0016835|GO:0017001|GO:0046677 CDC59_RS16490 33467f4c84cad0bcf18e9c2ba60f58f5 352 Gene3D G3DSA:2.130.10.10 32 158 3.8E-15 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CDC59_RS02155 176ded74e4468f4a0a5fecedb433da73 124 SUPERFAMILY SSF48300 3 60 4.05E-16 T 29-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS02155 176ded74e4468f4a0a5fecedb433da73 124 SUPERFAMILY SSF54736 53 124 8.72E-24 T 29-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CDC59_RS02155 176ded74e4468f4a0a5fecedb433da73 124 Gene3D G3DSA:3.30.1390.10 54 124 4.7E-29 T 29-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CDC59_RS02155 176ded74e4468f4a0a5fecedb433da73 124 Gene3D G3DSA:1.20.5.710 2 53 4.8E-16 T 29-03-2018 CDC59_RS02155 176ded74e4468f4a0a5fecedb433da73 124 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 2 124 24.222 T 29-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS02155 176ded74e4468f4a0a5fecedb433da73 124 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 58 124 1.4E-29 T 29-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS02155 176ded74e4468f4a0a5fecedb433da73 124 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 59 98 4.0E-14 T 29-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS02155 176ded74e4468f4a0a5fecedb433da73 124 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 124 1.7E-48 T 29-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS02155 176ded74e4468f4a0a5fecedb433da73 124 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 4 52 2.5E-18 T 29-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS11545 0928df3a15ff49e2db3fb2d779177d48 381 SUPERFAMILY SSF53187 106 378 7.33E-55 T 29-03-2018 CDC59_RS11545 0928df3a15ff49e2db3fb2d779177d48 381 Gene3D G3DSA:3.40.630.10 105 367 3.9E-43 T 29-03-2018 CDC59_RS11545 0928df3a15ff49e2db3fb2d779177d48 381 Pfam PF00246 Zinc carboxypeptidase 134 349 1.4E-19 T 29-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 CDC59_RS11545 0928df3a15ff49e2db3fb2d779177d48 381 SMART SM00631 72 361 0.0015 T 29-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 CDC59_RS14445 226d1a1f0f32a87412b4b243b7a0d76e 286 Pfam PF00510 Cytochrome c oxidase subunit III 11 285 1.3E-60 T 29-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS14445 226d1a1f0f32a87412b4b243b7a0d76e 286 SUPERFAMILY SSF81452 8 286 4.71E-82 T 29-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS14445 226d1a1f0f32a87412b4b243b7a0d76e 286 Gene3D G3DSA:1.10.287.70 1 74 8.4E-15 T 29-03-2018 CDC59_RS14445 226d1a1f0f32a87412b4b243b7a0d76e 286 Gene3D G3DSA:1.20.120.80 75 286 4.8E-74 T 29-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS02660 354ad79463cd8663e0546db84505a9f5 235 SMART SM00448 1 112 3.2E-34 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS02660 354ad79463cd8663e0546db84505a9f5 235 Pfam PF00072 Response regulator receiver domain 3 112 1.3E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS02660 354ad79463cd8663e0546db84505a9f5 235 Gene3D G3DSA:1.10.10.10 124 225 1.2E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS02660 354ad79463cd8663e0546db84505a9f5 235 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 218 2.7E-16 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDC59_RS02660 354ad79463cd8663e0546db84505a9f5 235 SUPERFAMILY SSF52172 1 129 3.98E-35 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS02660 354ad79463cd8663e0546db84505a9f5 235 Gene3D G3DSA:3.40.50.2300 1 123 1.1E-32 T 29-03-2018 CDC59_RS02660 354ad79463cd8663e0546db84505a9f5 235 SMART SM00862 145 218 5.1E-15 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDC59_RS02660 354ad79463cd8663e0546db84505a9f5 235 SUPERFAMILY SSF46894 120 220 3.68E-20 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CDC59_RS16505 4f86b4d09e7a623181d91294fd260da2 152 Pfam PF00376 MerR family regulatory protein 2 39 3.1E-14 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CDC59_RS16505 4f86b4d09e7a623181d91294fd260da2 152 Gene3D G3DSA:1.10.1660.10 1 56 1.6E-21 T 29-03-2018 CDC59_RS16505 4f86b4d09e7a623181d91294fd260da2 152 Pfam PF09278 MerR, DNA binding 44 107 2.1E-17 T 29-03-2018 IPR015358 Transcription regulator MerR, DNA binding CDC59_RS16505 4f86b4d09e7a623181d91294fd260da2 152 Gene3D G3DSA:1.10.1660.10 57 140 5.4E-15 T 29-03-2018 CDC59_RS16505 4f86b4d09e7a623181d91294fd260da2 152 SUPERFAMILY SSF46955 1 110 4.4E-29 T 29-03-2018 IPR009061 Putative DNA-binding domain CDC59_RS16505 4f86b4d09e7a623181d91294fd260da2 152 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 8.6E-9 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CDC59_RS16505 4f86b4d09e7a623181d91294fd260da2 152 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 8.6E-9 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CDC59_RS16505 4f86b4d09e7a623181d91294fd260da2 152 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 8.6E-9 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CDC59_RS16505 4f86b4d09e7a623181d91294fd260da2 152 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CDC59_RS16505 4f86b4d09e7a623181d91294fd260da2 152 SMART SM00422 1 70 1.9E-24 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CDC59_RS15080 c44cd914ff6d5f8a815ee15e9089b39f 285 Gene3D G3DSA:3.10.310.10 1 122 2.6E-25 T 29-03-2018 CDC59_RS15080 c44cd914ff6d5f8a815ee15e9089b39f 285 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 3 274 9.7E-47 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CDC59_RS15080 c44cd914ff6d5f8a815ee15e9089b39f 285 SUPERFAMILY SSF54506 4 284 1.23E-63 T 29-03-2018 CDC59_RS15080 c44cd914ff6d5f8a815ee15e9089b39f 285 PIRSF PIRSF016184 1 285 8.8E-66 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CDC59_RS15080 c44cd914ff6d5f8a815ee15e9089b39f 285 Gene3D G3DSA:3.10.310.10 123 274 4.6E-32 T 29-03-2018 CDC59_RS15080 c44cd914ff6d5f8a815ee15e9089b39f 285 Pfam PF02567 Phenazine biosynthesis-like protein 10 269 9.3E-44 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CDC59_RS07375 4021004f8a41af8c3d933e42326e9b0e 315 Gene3D G3DSA:3.30.300.20 204 315 4.2E-38 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CDC59_RS07375 4021004f8a41af8c3d933e42326e9b0e 315 Pfam PF07650 KH domain 227 302 9.8E-17 T 29-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS07375 4021004f8a41af8c3d933e42326e9b0e 315 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 27 47 2.5E-7 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CDC59_RS07375 4021004f8a41af8c3d933e42326e9b0e 315 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 95 113 2.5E-7 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CDC59_RS07375 4021004f8a41af8c3d933e42326e9b0e 315 Gene3D G3DSA:3.40.50.300 23 72 1.3E-15 T 29-03-2018 CDC59_RS07375 4021004f8a41af8c3d933e42326e9b0e 315 Gene3D G3DSA:3.40.50.300 73 193 3.0E-14 T 29-03-2018 CDC59_RS07375 4021004f8a41af8c3d933e42326e9b0e 315 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 25 188 3.9E-26 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CDC59_RS07375 4021004f8a41af8c3d933e42326e9b0e 315 SUPERFAMILY SSF52540 27 224 5.58E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS07375 4021004f8a41af8c3d933e42326e9b0e 315 Pfam PF01926 50S ribosome-binding GTPase 27 140 4.5E-25 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CDC59_RS07375 4021004f8a41af8c3d933e42326e9b0e 315 SUPERFAMILY SSF54814 201 315 1.05E-38 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CDC59_RS07375 4021004f8a41af8c3d933e42326e9b0e 315 TIGRFAM TIGR00436 era: GTP-binding protein Era 25 297 1.8E-81 T 29-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS07375 4021004f8a41af8c3d933e42326e9b0e 315 Hamap MF_00367 GTPase Era [era]. 22 314 34.368 T 29-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS01100 87becd1bb30d9a6a7d1aa9fce5f150da 446 SUPERFAMILY SSF118215 8 404 2.62E-108 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CDC59_RS01100 87becd1bb30d9a6a7d1aa9fce5f150da 446 Pfam PF00375 Sodium:dicarboxylate symporter family 8 403 3.5E-100 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CDC59_RS01100 87becd1bb30d9a6a7d1aa9fce5f150da 446 Hamap MF_01300 C4-dicarboxylate transport protein [dctA]. 1 430 36.992 T 29-03-2018 IPR023954 C4-dicarboxylate transport protein GO:0006835|GO:0015293|GO:0016021 CDC59_RS01100 87becd1bb30d9a6a7d1aa9fce5f150da 446 PRINTS PR00173 Glutamate-aspartate symporter signature 147 169 2.6E-22 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CDC59_RS01100 87becd1bb30d9a6a7d1aa9fce5f150da 446 PRINTS PR00173 Glutamate-aspartate symporter signature 194 213 2.6E-22 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CDC59_RS01100 87becd1bb30d9a6a7d1aa9fce5f150da 446 PRINTS PR00173 Glutamate-aspartate symporter signature 73 98 2.6E-22 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CDC59_RS01100 87becd1bb30d9a6a7d1aa9fce5f150da 446 PRINTS PR00173 Glutamate-aspartate symporter signature 6 26 2.6E-22 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CDC59_RS01100 87becd1bb30d9a6a7d1aa9fce5f150da 446 PRINTS PR00173 Glutamate-aspartate symporter signature 294 320 2.6E-22 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CDC59_RS01100 87becd1bb30d9a6a7d1aa9fce5f150da 446 PRINTS PR00173 Glutamate-aspartate symporter signature 329 348 2.6E-22 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CDC59_RS01100 87becd1bb30d9a6a7d1aa9fce5f150da 446 Gene3D G3DSA:1.10.3860.10 3 410 1.5E-106 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CDC59_RS01100 87becd1bb30d9a6a7d1aa9fce5f150da 446 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 35 50 - T 29-03-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site CDC59_RS01100 87becd1bb30d9a6a7d1aa9fce5f150da 446 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 297 320 - T 29-03-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site CDC59_RS03275 aa4e4191c7a0a3795669255119e08833 574 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 461 2.7E-47 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDC59_RS03275 aa4e4191c7a0a3795669255119e08833 574 SUPERFAMILY SSF55681 409 480 5.18E-102 T 29-03-2018 CDC59_RS03275 aa4e4191c7a0a3795669255119e08833 574 SUPERFAMILY SSF55681 10 237 5.18E-102 T 29-03-2018 CDC59_RS03275 aa4e4191c7a0a3795669255119e08833 574 PIRSF PIRSF001535 1 574 3.1E-267 T 29-03-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 CDC59_RS03275 aa4e4191c7a0a3795669255119e08833 574 Gene3D G3DSA:3.30.930.10 11 462 4.5E-99 T 29-03-2018 CDC59_RS03275 aa4e4191c7a0a3795669255119e08833 574 Pfam PF04073 Aminoacyl-tRNA editing domain 257 381 5.9E-29 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CDC59_RS03275 aa4e4191c7a0a3795669255119e08833 574 SUPERFAMILY SSF52954 466 573 4.08E-30 T 29-03-2018 IPR004154 Anticodon-binding CDC59_RS03275 aa4e4191c7a0a3795669255119e08833 574 SUPERFAMILY SSF55826 218 392 7.85E-37 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CDC59_RS03275 aa4e4191c7a0a3795669255119e08833 574 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 1.5E-18 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CDC59_RS03275 aa4e4191c7a0a3795669255119e08833 574 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 1.5E-18 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CDC59_RS03275 aa4e4191c7a0a3795669255119e08833 574 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 1.5E-18 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CDC59_RS03275 aa4e4191c7a0a3795669255119e08833 574 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 1.5E-18 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CDC59_RS03275 aa4e4191c7a0a3795669255119e08833 574 Pfam PF03129 Anticodon binding domain 477 570 4.7E-18 T 29-03-2018 IPR004154 Anticodon-binding CDC59_RS03275 aa4e4191c7a0a3795669255119e08833 574 Gene3D G3DSA:3.40.50.800 463 574 1.1E-31 T 29-03-2018 IPR004154 Anticodon-binding CDC59_RS03275 aa4e4191c7a0a3795669255119e08833 574 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 573 40.93 T 29-03-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 CDC59_RS03275 aa4e4191c7a0a3795669255119e08833 574 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 568 3.9E-225 T 29-03-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 CDC59_RS23090 ee525035ac21cb9ae4d189e2f54fce58 292 SUPERFAMILY SSF47757 12 88 1.07E-21 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CDC59_RS23090 ee525035ac21cb9ae4d189e2f54fce58 292 PIRSF PIRSF000410 2 283 3.1E-95 T 29-03-2018 IPR026024 Chemotaxis protein methyltransferase CheR CDC59_RS23090 ee525035ac21cb9ae4d189e2f54fce58 292 SUPERFAMILY SSF53335 89 279 2.07E-56 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS23090 ee525035ac21cb9ae4d189e2f54fce58 292 Gene3D G3DSA:3.40.50.150 88 282 1.6E-45 T 29-03-2018 CDC59_RS23090 ee525035ac21cb9ae4d189e2f54fce58 292 Pfam PF03705 CheR methyltransferase, all-alpha domain 22 73 2.9E-17 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CDC59_RS23090 ee525035ac21cb9ae4d189e2f54fce58 292 Gene3D G3DSA:1.10.155.10 13 87 4.7E-23 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CDC59_RS23090 ee525035ac21cb9ae4d189e2f54fce58 292 Pfam PF01739 CheR methyltransferase, SAM binding domain 89 273 1.5E-57 T 29-03-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal CDC59_RS23090 ee525035ac21cb9ae4d189e2f54fce58 292 SMART SM00138 21 282 4.7E-96 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CDC59_RS23090 ee525035ac21cb9ae4d189e2f54fce58 292 PRINTS PR00996 Glutamate methyltransferase family signature 43 56 1.4E-43 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CDC59_RS23090 ee525035ac21cb9ae4d189e2f54fce58 292 PRINTS PR00996 Glutamate methyltransferase family signature 82 94 1.4E-43 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CDC59_RS23090 ee525035ac21cb9ae4d189e2f54fce58 292 PRINTS PR00996 Glutamate methyltransferase family signature 115 135 1.4E-43 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CDC59_RS23090 ee525035ac21cb9ae4d189e2f54fce58 292 PRINTS PR00996 Glutamate methyltransferase family signature 150 166 1.4E-43 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CDC59_RS23090 ee525035ac21cb9ae4d189e2f54fce58 292 PRINTS PR00996 Glutamate methyltransferase family signature 222 236 1.4E-43 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CDC59_RS23090 ee525035ac21cb9ae4d189e2f54fce58 292 PRINTS PR00996 Glutamate methyltransferase family signature 241 264 1.4E-43 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CDC59_RS10675 c0d39e27ad6a1268e267e95e8b7199ce 146 Gene3D G3DSA:1.10.1660.10 16 145 5.5E-26 T 29-03-2018 CDC59_RS10675 c0d39e27ad6a1268e267e95e8b7199ce 146 Pfam PF13411 MerR HTH family regulatory protein 21 90 2.5E-21 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CDC59_RS10675 c0d39e27ad6a1268e267e95e8b7199ce 146 SMART SM00422 21 91 4.7E-6 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CDC59_RS10675 c0d39e27ad6a1268e267e95e8b7199ce 146 SUPERFAMILY SSF46955 19 102 6.41E-18 T 29-03-2018 IPR009061 Putative DNA-binding domain CDC59_RS01355 36cc505240f265e695490ca27c687258 167 Pfam PF15428 Immunity protein 26 20 101 8.7E-12 T 29-03-2018 IPR029278 Immunity protein 26 CDC59_RS21145 31d057c2a5778cd8b29131f543de63c8 144 Pfam PF04972 BON domain 49 117 6.8E-12 T 29-03-2018 IPR007055 BON domain CDC59_RS21145 31d057c2a5778cd8b29131f543de63c8 144 SMART SM00749 54 117 2.8E-7 T 29-03-2018 IPR014004 Transport-associated and nodulation domain, bacteria CDC59_RS22755 6514e06e262bb1d47499d17a1f1e8f6b 274 Gene3D G3DSA:3.40.50.10490 115 272 1.8E-33 T 29-03-2018 CDC59_RS22755 6514e06e262bb1d47499d17a1f1e8f6b 274 Gene3D G3DSA:1.10.10.10 12 114 2.6E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS22755 6514e06e262bb1d47499d17a1f1e8f6b 274 SUPERFAMILY SSF53697 103 270 2.38E-35 T 29-03-2018 CDC59_RS22755 6514e06e262bb1d47499d17a1f1e8f6b 274 Pfam PF01380 SIS domain 133 257 3.4E-18 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CDC59_RS22755 6514e06e262bb1d47499d17a1f1e8f6b 274 Pfam PF01418 Helix-turn-helix domain, rpiR family 15 84 3.0E-19 T 29-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CDC59_RS22755 6514e06e262bb1d47499d17a1f1e8f6b 274 SUPERFAMILY SSF46689 14 85 3.94E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS10060 7162595d8e53b1200200b4f713c1c281 363 SUPERFAMILY SSF50331 241 362 6.23E-16 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CDC59_RS10060 7162595d8e53b1200200b4f713c1c281 363 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 39 336 5.0E-108 T 29-03-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 CDC59_RS10060 7162595d8e53b1200200b4f713c1c281 363 Pfam PF08402 TOBE domain 284 362 1.9E-16 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CDC59_RS10060 7162595d8e53b1200200b4f713c1c281 363 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS10060 7162595d8e53b1200200b4f713c1c281 363 Gene3D G3DSA:2.40.50.100 245 295 4.3E-4 T 29-03-2018 CDC59_RS10060 7162595d8e53b1200200b4f713c1c281 363 Pfam PF00005 ABC transporter 25 166 1.1E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS10060 7162595d8e53b1200200b4f713c1c281 363 Gene3D G3DSA:3.40.50.300 3 244 1.1E-69 T 29-03-2018 CDC59_RS10060 7162595d8e53b1200200b4f713c1c281 363 SMART SM00382 33 216 2.8E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS10060 7162595d8e53b1200200b4f713c1c281 363 Gene3D G3DSA:2.40.50.140 296 354 5.5E-4 T 29-03-2018 CDC59_RS10060 7162595d8e53b1200200b4f713c1c281 363 SUPERFAMILY SSF52540 8 247 4.5E-85 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS10995 15bda87aebe7e9a03fd201853a35ef34 258 SUPERFAMILY SSF53335 69 208 6.09E-18 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS10995 15bda87aebe7e9a03fd201853a35ef34 258 Gene3D G3DSA:3.40.50.150 46 210 1.6E-13 T 29-03-2018 CDC59_RS10995 15bda87aebe7e9a03fd201853a35ef34 258 Pfam PF08241 Methyltransferase domain 68 116 2.7E-9 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CDC59_RS10540 d3885161b535d69d3ee8f7fd590fddc3 268 SUPERFAMILY SSF51621 1 253 3.71E-84 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CDC59_RS10540 d3885161b535d69d3ee8f7fd590fddc3 268 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 18 243 3.1E-60 T 29-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 CDC59_RS10540 d3885161b535d69d3ee8f7fd590fddc3 268 TIGRFAM TIGR02311 HpaI: 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase 6 253 9.1E-123 T 29-03-2018 IPR012689 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase GO:0010124|GO:0018802 KEGG: 00350+4.1.2.52 CDC59_RS10540 d3885161b535d69d3ee8f7fd590fddc3 268 Gene3D G3DSA:3.20.20.60 2 262 1.1E-51 T 29-03-2018 CDC59_RS00590 2e8aa24d4d0277d80131e7f69c0c9137 84 SUPERFAMILY SSF55229 35 83 1.57E-14 T 29-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 CDC59_RS00590 2e8aa24d4d0277d80131e7f69c0c9137 84 Pfam PF03776 Septum formation topological specificity factor MinE 14 82 3.6E-25 T 29-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 CDC59_RS00590 2e8aa24d4d0277d80131e7f69c0c9137 84 Hamap MF_00262 Cell division topological specificity factor [minE]. 3 84 18.459 T 29-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 CDC59_RS00590 2e8aa24d4d0277d80131e7f69c0c9137 84 Gene3D G3DSA:3.30.1070.10 1 83 9.8E-28 T 29-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 CDC59_RS00590 2e8aa24d4d0277d80131e7f69c0c9137 84 TIGRFAM TIGR01215 minE: cell division topological specificity factor MinE 1 82 1.3E-28 T 29-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 CDC59_RS18190 e2b29694743cc89ea18d8a99666602aa 887 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 569 859 2.0E-96 T 29-03-2018 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal CDC59_RS18190 e2b29694743cc89ea18d8a99666602aa 887 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 53 335 1.1E-15 T 29-03-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD CDC59_RS18190 e2b29694743cc89ea18d8a99666602aa 887 SUPERFAMILY SSF55729 675 857 5.19E-11 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDC59_RS18190 e2b29694743cc89ea18d8a99666602aa 887 Gene3D G3DSA:3.40.630.30 662 852 6.3E-14 T 29-03-2018 CDC59_RS20050 c66da4b5e5b90d8024ddbf8eb3203e49 345 SUPERFAMILY SSF52374 12 176 7.51E-25 T 29-03-2018 CDC59_RS20050 c66da4b5e5b90d8024ddbf8eb3203e49 345 Pfam PF01467 Cytidylyltransferase-like 12 149 1.5E-9 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CDC59_RS20050 c66da4b5e5b90d8024ddbf8eb3203e49 345 PRINTS PR00502 NUDIX hydrolase family signature 248 263 2.4E-5 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CDC59_RS20050 c66da4b5e5b90d8024ddbf8eb3203e49 345 PRINTS PR00502 NUDIX hydrolase family signature 234 248 2.4E-5 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CDC59_RS20050 c66da4b5e5b90d8024ddbf8eb3203e49 345 SUPERFAMILY SSF55811 198 343 7.04E-31 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CDC59_RS20050 c66da4b5e5b90d8024ddbf8eb3203e49 345 Pfam PF00293 NUDIX domain 210 328 1.2E-18 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CDC59_RS20050 c66da4b5e5b90d8024ddbf8eb3203e49 345 Gene3D G3DSA:3.90.79.10 201 345 4.8E-31 T 29-03-2018 CDC59_RS20050 c66da4b5e5b90d8024ddbf8eb3203e49 345 Gene3D G3DSA:3.40.50.620 2 200 9.9E-37 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDC59_RS20050 c66da4b5e5b90d8024ddbf8eb3203e49 345 ProSitePatterns PS00893 Nudix box signature. 239 260 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CDC59_RS20050 c66da4b5e5b90d8024ddbf8eb3203e49 345 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 12 67 4.1E-11 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CDC59_RS22185 933ec94c9bac2de58f18ea74ef6fcfca 392 SUPERFAMILY SSF50939 310 391 3.64E-56 T 29-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 CDC59_RS22185 933ec94c9bac2de58f18ea74ef6fcfca 392 SUPERFAMILY SSF50939 32 277 3.64E-56 T 29-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 CDC59_RS22185 933ec94c9bac2de58f18ea74ef6fcfca 392 Pfam PF13088 BNR repeat-like domain 47 371 3.9E-72 T 29-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 CDC59_RS22185 933ec94c9bac2de58f18ea74ef6fcfca 392 Gene3D G3DSA:2.120.10.10 16 392 2.3E-59 T 29-03-2018 CDC59_RS07320 d42f32d93aa034fe8beef172f5c4513d 410 Gene3D G3DSA:3.40.47.10 6 260 3.4E-83 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS07320 d42f32d93aa034fe8beef172f5c4513d 410 SUPERFAMILY SSF53901 4 252 9.43E-80 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS07320 d42f32d93aa034fe8beef172f5c4513d 410 Gene3D G3DSA:3.40.47.10 261 410 9.0E-49 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS07320 d42f32d93aa034fe8beef172f5c4513d 410 SUPERFAMILY SSF53901 214 409 2.07E-68 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS07320 d42f32d93aa034fe8beef172f5c4513d 410 PIRSF PIRSF000447 1 410 2.4E-185 T 29-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 CDC59_RS07320 d42f32d93aa034fe8beef172f5c4513d 410 SMART SM00825 Beta-ketoacyl synthase 6 410 2.0E-15 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CDC59_RS07320 d42f32d93aa034fe8beef172f5c4513d 410 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 155 171 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site CDC59_RS07320 d42f32d93aa034fe8beef172f5c4513d 410 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 255 367 1.1E-35 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CDC59_RS07320 d42f32d93aa034fe8beef172f5c4513d 410 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 246 2.9E-60 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CDC59_RS07320 d42f32d93aa034fe8beef172f5c4513d 410 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 4 408 2.8E-197 T 29-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 CDC59_RS11705 4fd204d0ecbbc7220d6d98329a6a371a 418 Pfam PF13433 Periplasmic binding protein domain 32 407 1.3E-171 T 29-03-2018 CDC59_RS11705 4fd204d0ecbbc7220d6d98329a6a371a 418 SUPERFAMILY SSF53822 31 408 9.42E-91 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CDC59_RS11705 4fd204d0ecbbc7220d6d98329a6a371a 418 Gene3D G3DSA:3.40.50.2300 158 346 1.6E-27 T 29-03-2018 CDC59_RS11705 4fd204d0ecbbc7220d6d98329a6a371a 418 Gene3D G3DSA:3.40.50.2300 19 157 7.6E-23 T 29-03-2018 CDC59_RS11705 4fd204d0ecbbc7220d6d98329a6a371a 418 TIGRFAM TIGR03407 urea_ABC_UrtA: urea ABC transporter, urea binding protein 32 404 1.7E-180 T 29-03-2018 IPR017777 Urea ABC transporter, substrate-binding protein UrtA-like CDC59_RS02770 daa1149d70d50d5a87eb77031ec4b7fb 555 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 2 552 2.5E-296 T 29-03-2018 IPR022374 ABC transporter, ATP-binding protein, ChvD CDC59_RS02770 daa1149d70d50d5a87eb77031ec4b7fb 555 SUPERFAMILY SSF52540 12 236 5.24E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS02770 daa1149d70d50d5a87eb77031ec4b7fb 555 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS02770 daa1149d70d50d5a87eb77031ec4b7fb 555 Pfam PF00005 ABC transporter 22 191 7.1E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS02770 daa1149d70d50d5a87eb77031ec4b7fb 555 Pfam PF00005 ABC transporter 340 473 1.1E-23 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS02770 daa1149d70d50d5a87eb77031ec4b7fb 555 SMART SM00382 348 526 2.7E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS02770 daa1149d70d50d5a87eb77031ec4b7fb 555 SMART SM00382 31 236 1.5E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS02770 daa1149d70d50d5a87eb77031ec4b7fb 555 Gene3D G3DSA:3.40.50.300 12 289 2.6E-54 T 29-03-2018 CDC59_RS02770 daa1149d70d50d5a87eb77031ec4b7fb 555 Gene3D G3DSA:3.40.50.300 290 550 3.5E-57 T 29-03-2018 CDC59_RS02770 daa1149d70d50d5a87eb77031ec4b7fb 555 Pfam PF12848 ABC transporter 230 306 3.9E-12 T 29-03-2018 IPR032781 ABC-transporter extension domain CDC59_RS02770 daa1149d70d50d5a87eb77031ec4b7fb 555 SUPERFAMILY SSF52540 301 523 1.75E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS16155 a0a5001250ca80a84e001076e076f15f 266 Pfam PF03781 Sulfatase-modifying factor enzyme 1 26 259 2.9E-27 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 CDC59_RS16155 a0a5001250ca80a84e001076e076f15f 266 Gene3D G3DSA:3.90.1580.10 18 265 7.3E-32 T 29-03-2018 CDC59_RS16155 a0a5001250ca80a84e001076e076f15f 266 SUPERFAMILY SSF56436 28 261 2.64E-35 T 29-03-2018 IPR016187 C-type lectin fold CDC59_RS10765 b10ce0b01102fd63ee7ad8b72d27c51e 366 TIGRFAM TIGR00033 aroC: chorismate synthase 10 350 1.9E-141 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CDC59_RS10765 b10ce0b01102fd63ee7ad8b72d27c51e 366 Hamap MF_00300 Chorismate synthase [aroC]. 10 354 36.46 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CDC59_RS10765 b10ce0b01102fd63ee7ad8b72d27c51e 366 ProSitePatterns PS00788 Chorismate synthase signature 2. 124 140 - T 29-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CDC59_RS10765 b10ce0b01102fd63ee7ad8b72d27c51e 366 SUPERFAMILY SSF103263 4 352 3.66E-146 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CDC59_RS10765 b10ce0b01102fd63ee7ad8b72d27c51e 366 PIRSF PIRSF001456 3 363 3.6E-135 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CDC59_RS10765 b10ce0b01102fd63ee7ad8b72d27c51e 366 Gene3D G3DSA:3.60.150.10 9 365 2.0E-153 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CDC59_RS10765 b10ce0b01102fd63ee7ad8b72d27c51e 366 ProSitePatterns PS00787 Chorismate synthase signature 1. 16 31 - T 29-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CDC59_RS10765 b10ce0b01102fd63ee7ad8b72d27c51e 366 ProSitePatterns PS00789 Chorismate synthase signature 3. 319 335 - T 29-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CDC59_RS10765 b10ce0b01102fd63ee7ad8b72d27c51e 366 Pfam PF01264 Chorismate synthase 10 345 2.0E-135 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CDC59_RS12115 b23aaacb65426d7d8db34312a836993e 478 Gene3D G3DSA:3.40.309.10 263 459 1.2E-60 T 29-03-2018 CDC59_RS12115 b23aaacb65426d7d8db34312a836993e 478 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 246 253 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CDC59_RS12115 b23aaacb65426d7d8db34312a836993e 478 SUPERFAMILY SSF53720 2 476 3.27E-153 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CDC59_RS12115 b23aaacb65426d7d8db34312a836993e 478 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 274 285 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CDC59_RS12115 b23aaacb65426d7d8db34312a836993e 478 Gene3D G3DSA:3.40.605.10 1 262 2.9E-94 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CDC59_RS12115 b23aaacb65426d7d8db34312a836993e 478 Pfam PF00171 Aldehyde dehydrogenase family 18 473 2.1E-155 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CDC59_RS16095 e4aa1fdeea968ac6f40aa7504ddfad39 1052 Gene3D G3DSA:1.20.1640.10 833 1041 1.3E-38 T 29-03-2018 CDC59_RS16095 e4aa1fdeea968ac6f40aa7504ddfad39 1052 SUPERFAMILY SSF82693 46 128 7.85E-15 T 29-03-2018 CDC59_RS16095 e4aa1fdeea968ac6f40aa7504ddfad39 1052 PRINTS PR00702 Acriflavin resistance protein family signature 556 573 1.6E-16 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS16095 e4aa1fdeea968ac6f40aa7504ddfad39 1052 PRINTS PR00702 Acriflavin resistance protein family signature 626 640 1.6E-16 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS16095 e4aa1fdeea968ac6f40aa7504ddfad39 1052 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 1.6E-16 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS16095 e4aa1fdeea968ac6f40aa7504ddfad39 1052 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 1.6E-16 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS16095 e4aa1fdeea968ac6f40aa7504ddfad39 1052 PRINTS PR00702 Acriflavin resistance protein family signature 332 355 1.6E-16 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS16095 e4aa1fdeea968ac6f40aa7504ddfad39 1052 PRINTS PR00702 Acriflavin resistance protein family signature 12 36 1.6E-16 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS16095 e4aa1fdeea968ac6f40aa7504ddfad39 1052 SUPERFAMILY SSF82714 183 264 3.92E-15 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS16095 e4aa1fdeea968ac6f40aa7504ddfad39 1052 SUPERFAMILY SSF82693 571 658 2.93E-8 T 29-03-2018 CDC59_RS16095 e4aa1fdeea968ac6f40aa7504ddfad39 1052 Pfam PF00873 AcrB/AcrD/AcrF family 6 1038 5.0E-242 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS16095 e4aa1fdeea968ac6f40aa7504ddfad39 1052 SUPERFAMILY SSF82866 816 1042 4.84E-51 T 29-03-2018 CDC59_RS16095 e4aa1fdeea968ac6f40aa7504ddfad39 1052 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 3 1046 6.1E-268 T 29-03-2018 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 CDC59_RS16095 e4aa1fdeea968ac6f40aa7504ddfad39 1052 SUPERFAMILY SSF82866 293 510 6.02E-34 T 29-03-2018 CDC59_RS16095 e4aa1fdeea968ac6f40aa7504ddfad39 1052 Gene3D G3DSA:3.30.2090.10 727 819 1.2E-20 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS16095 e4aa1fdeea968ac6f40aa7504ddfad39 1052 Gene3D G3DSA:3.30.2090.10 180 266 2.4E-17 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS16095 e4aa1fdeea968ac6f40aa7504ddfad39 1052 Gene3D G3DSA:3.30.70.1430 43 134 1.7E-13 T 29-03-2018 CDC59_RS16095 e4aa1fdeea968ac6f40aa7504ddfad39 1052 Gene3D G3DSA:1.20.1640.10 281 521 3.9E-40 T 29-03-2018 CDC59_RS16095 e4aa1fdeea968ac6f40aa7504ddfad39 1052 SUPERFAMILY SSF82714 728 818 1.09E-16 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS16095 e4aa1fdeea968ac6f40aa7504ddfad39 1052 Gene3D G3DSA:3.30.70.1430 571 673 4.5E-13 T 29-03-2018 CDC59_RS16095 e4aa1fdeea968ac6f40aa7504ddfad39 1052 SUPERFAMILY SSF82693 147 181 7.85E-14 T 29-03-2018 CDC59_RS16095 e4aa1fdeea968ac6f40aa7504ddfad39 1052 SUPERFAMILY SSF82693 268 326 7.85E-14 T 29-03-2018 CDC59_RS13530 0fb87f1da272d230ab4add6e80cf227a 470 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 303 314 2.6E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS13530 0fb87f1da272d230ab4add6e80cf227a 470 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 356 364 2.6E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS13530 0fb87f1da272d230ab4add6e80cf227a 470 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 376 395 2.6E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS13530 0fb87f1da272d230ab4add6e80cf227a 470 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 232 407 1.8E-6 T 29-03-2018 CDC59_RS13530 0fb87f1da272d230ab4add6e80cf227a 470 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 238 463 8.2E-49 T 29-03-2018 CDC59_RS13530 0fb87f1da272d230ab4add6e80cf227a 470 SUPERFAMILY SSF51735 228 464 6.57E-60 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS13530 0fb87f1da272d230ab4add6e80cf227a 470 Gene3D G3DSA:3.40.50.720 115 223 0.0041 T 29-03-2018 CDC59_RS13530 0fb87f1da272d230ab4add6e80cf227a 470 Gene3D G3DSA:3.40.50.720 270 468 1.1E-49 T 29-03-2018 CDC59_RS13530 0fb87f1da272d230ab4add6e80cf227a 470 Gene3D G3DSA:3.40.50.720 224 269 5.4E-10 T 29-03-2018 CDC59_RS13530 0fb87f1da272d230ab4add6e80cf227a 470 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 350 366 3.3E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS13530 0fb87f1da272d230ab4add6e80cf227a 470 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 376 395 3.3E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS13530 0fb87f1da272d230ab4add6e80cf227a 470 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 303 314 3.3E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS13530 0fb87f1da272d230ab4add6e80cf227a 470 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 430 450 3.3E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS13530 0fb87f1da272d230ab4add6e80cf227a 470 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 397 414 3.3E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS13530 0fb87f1da272d230ab4add6e80cf227a 470 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 233 250 3.3E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS19865 1de6b8fc8a3e25a15fbd683380aa8136 239 Gene3D G3DSA:2.60.120.10 14 160 3.6E-22 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CDC59_RS19865 1de6b8fc8a3e25a15fbd683380aa8136 239 SMART SM00100 25 143 1.6E-11 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CDC59_RS19865 1de6b8fc8a3e25a15fbd683380aa8136 239 Pfam PF13545 Crp-like helix-turn-helix domain 163 236 1.0E-14 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CDC59_RS19865 1de6b8fc8a3e25a15fbd683380aa8136 239 SUPERFAMILY SSF46785 161 237 4.36E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS19865 1de6b8fc8a3e25a15fbd683380aa8136 239 SUPERFAMILY SSF51206 20 154 7.73E-29 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like CDC59_RS19865 1de6b8fc8a3e25a15fbd683380aa8136 239 Gene3D G3DSA:1.10.10.10 161 239 1.7E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS19865 1de6b8fc8a3e25a15fbd683380aa8136 239 Pfam PF00027 Cyclic nucleotide-binding domain 44 130 2.3E-19 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CDC59_RS19865 1de6b8fc8a3e25a15fbd683380aa8136 239 SMART SM00419 181 229 1.8E-9 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CDC59_RS18250 4b8fa8ef0c0e5805391a526dae38937d 72 Pfam PF06348 Protein of unknown function (DUF1059) 6 58 4.3E-9 T 29-03-2018 IPR009409 Protein of unknown function DUF1059 CDC59_RS03725 06620cd08f6af7f14439e9038b151906 111 SMART SM01323 21 103 4.5E-49 T 29-03-2018 IPR003849 Preprotein translocase YajC CDC59_RS03725 06620cd08f6af7f14439e9038b151906 111 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 23 103 3.5E-30 T 29-03-2018 IPR003849 Preprotein translocase YajC CDC59_RS03725 06620cd08f6af7f14439e9038b151906 111 PRINTS PR01853 Bacterial YajC preprotein translocase signature 61 79 8.9E-17 T 29-03-2018 IPR003849 Preprotein translocase YajC CDC59_RS03725 06620cd08f6af7f14439e9038b151906 111 PRINTS PR01853 Bacterial YajC preprotein translocase signature 23 43 8.9E-17 T 29-03-2018 IPR003849 Preprotein translocase YajC CDC59_RS03725 06620cd08f6af7f14439e9038b151906 111 Pfam PF02699 Preprotein translocase subunit 24 100 6.0E-32 T 29-03-2018 IPR003849 Preprotein translocase YajC CDC59_RS09860 c5c5ad3eba3b83ffe1a013dbb7f07291 282 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 271 7.2E-16 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS09860 c5c5ad3eba3b83ffe1a013dbb7f07291 282 Gene3D G3DSA:1.10.3720.10 19 274 3.1E-35 T 29-03-2018 CDC59_RS09860 c5c5ad3eba3b83ffe1a013dbb7f07291 282 SUPERFAMILY SSF161098 17 271 8.24E-47 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS16890 f2abefe66de4ae70141ff29aea4ba45a 477 SUPERFAMILY SSF90123 37 314 2.88E-9 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CDC59_RS16890 f2abefe66de4ae70141ff29aea4ba45a 477 Gene3D G3DSA:3.40.50.300 389 475 7.6E-5 T 29-03-2018 CDC59_RS16890 f2abefe66de4ae70141ff29aea4ba45a 477 Gene3D G3DSA:3.40.50.300 351 388 0.0032 T 29-03-2018 CDC59_RS16890 f2abefe66de4ae70141ff29aea4ba45a 477 SUPERFAMILY SSF52540 351 470 3.05E-7 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS00175 319e5c10a379a61e069145e39316d853 508 Gene3D G3DSA:1.10.10.10 14 85 4.5E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS00175 319e5c10a379a61e069145e39316d853 508 SMART SM00345 24 83 2.0E-11 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDC59_RS00175 319e5c10a379a61e069145e39316d853 508 Gene3D G3DSA:3.40.640.10 153 399 4.8E-46 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDC59_RS00175 319e5c10a379a61e069145e39316d853 508 Gene3D G3DSA:3.90.1150.10 400 499 5.6E-20 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS00175 319e5c10a379a61e069145e39316d853 508 Pfam PF00392 Bacterial regulatory proteins, gntR family 23 83 6.3E-12 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDC59_RS00175 319e5c10a379a61e069145e39316d853 508 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 57 73 3.0E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDC59_RS00175 319e5c10a379a61e069145e39316d853 508 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 57 3.0E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDC59_RS00175 319e5c10a379a61e069145e39316d853 508 SUPERFAMILY SSF53383 130 497 2.84E-89 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS00175 319e5c10a379a61e069145e39316d853 508 SUPERFAMILY SSF53383 78 102 2.84E-89 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS00175 319e5c10a379a61e069145e39316d853 508 SUPERFAMILY SSF46785 18 86 4.08E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS00175 319e5c10a379a61e069145e39316d853 508 Pfam PF00155 Aminotransferase class I and II 167 449 2.5E-22 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CDC59_RS10245 e9f36eb84fad9d67b123c7d6112a8d51 453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 412 430 5.1E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS10245 e9f36eb84fad9d67b123c7d6112a8d51 453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 378 392 5.1E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS10245 e9f36eb84fad9d67b123c7d6112a8d51 453 Gene3D G3DSA:3.30.565.10 294 448 1.0E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS10245 e9f36eb84fad9d67b123c7d6112a8d51 453 Pfam PF00672 HAMP domain 188 235 1.7E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CDC59_RS10245 e9f36eb84fad9d67b123c7d6112a8d51 453 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 342 438 5.9E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS10245 e9f36eb84fad9d67b123c7d6112a8d51 453 SUPERFAMILY SSF47384 225 296 9.81E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS10245 e9f36eb84fad9d67b123c7d6112a8d51 453 Pfam PF16524 Periplasmic domain of Sensor histidine kinase RisS 52 158 7.0E-39 T 29-03-2018 IPR032408 Sensor histidine kinase RisS, periplasmic domain CDC59_RS10245 e9f36eb84fad9d67b123c7d6112a8d51 453 Gene3D G3DSA:1.10.287.130 230 293 1.6E-10 T 29-03-2018 CDC59_RS10245 e9f36eb84fad9d67b123c7d6112a8d51 453 SMART SM00388 240 299 6.0E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS10245 e9f36eb84fad9d67b123c7d6112a8d51 453 SUPERFAMILY SSF55874 289 440 7.47E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS10245 e9f36eb84fad9d67b123c7d6112a8d51 453 SMART SM00304 187 239 2.6E-11 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CDC59_RS10245 e9f36eb84fad9d67b123c7d6112a8d51 453 Pfam PF00512 His Kinase A (phospho-acceptor) domain 244 296 3.4E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS10245 e9f36eb84fad9d67b123c7d6112a8d51 453 SUPERFAMILY SSF158472 189 236 1.05E-5 T 29-03-2018 CDC59_RS10245 e9f36eb84fad9d67b123c7d6112a8d51 453 SMART SM00387 337 452 4.9E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS01385 486d8739f7c105af0f0c084e0d7a595b 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS01385 486d8739f7c105af0f0c084e0d7a595b 328 Pfam PF05598 Transposase domain (DUF772) 51 126 5.1E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS19600 486d8739f7c105af0f0c084e0d7a595b 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS19600 486d8739f7c105af0f0c084e0d7a595b 328 Pfam PF05598 Transposase domain (DUF772) 51 126 5.1E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS04280 486d8739f7c105af0f0c084e0d7a595b 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS04280 486d8739f7c105af0f0c084e0d7a595b 328 Pfam PF05598 Transposase domain (DUF772) 51 126 5.1E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS01375 486d8739f7c105af0f0c084e0d7a595b 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS01375 486d8739f7c105af0f0c084e0d7a595b 328 Pfam PF05598 Transposase domain (DUF772) 51 126 5.1E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS15240 486d8739f7c105af0f0c084e0d7a595b 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS15240 486d8739f7c105af0f0c084e0d7a595b 328 Pfam PF05598 Transposase domain (DUF772) 51 126 5.1E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS04790 486d8739f7c105af0f0c084e0d7a595b 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS04790 486d8739f7c105af0f0c084e0d7a595b 328 Pfam PF05598 Transposase domain (DUF772) 51 126 5.1E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS00360 486d8739f7c105af0f0c084e0d7a595b 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS00360 486d8739f7c105af0f0c084e0d7a595b 328 Pfam PF05598 Transposase domain (DUF772) 51 126 5.1E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS16425 486d8739f7c105af0f0c084e0d7a595b 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS16425 486d8739f7c105af0f0c084e0d7a595b 328 Pfam PF05598 Transposase domain (DUF772) 51 126 5.1E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS09590 d4687035c1b83455f6df4b127981c572 468 SUPERFAMILY SSF53383 26 450 1.96E-118 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS09590 d4687035c1b83455f6df4b127981c572 468 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 265 302 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CDC59_RS09590 d4687035c1b83455f6df4b127981c572 468 Gene3D G3DSA:3.90.1150.10 13 209 4.1E-46 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS09590 d4687035c1b83455f6df4b127981c572 468 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 28 448 1.7E-152 T 29-03-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 CDC59_RS09590 d4687035c1b83455f6df4b127981c572 468 Pfam PF00202 Aminotransferase class-III 41 448 3.8E-110 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CDC59_RS09590 d4687035c1b83455f6df4b127981c572 468 Gene3D G3DSA:3.90.1150.10 343 452 7.2E-14 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS09590 d4687035c1b83455f6df4b127981c572 468 PIRSF PIRSF000521 43 454 1.3E-29 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CDC59_RS09590 d4687035c1b83455f6df4b127981c572 468 Gene3D G3DSA:3.40.640.10 210 342 3.6E-40 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDC59_RS18360 080d7b7bbb1803cc92277f8f17c82041 649 SMART SM00065 287 437 7.1E-6 T 29-03-2018 IPR003018 GAF domain GO:0005515 CDC59_RS18360 080d7b7bbb1803cc92277f8f17c82041 649 Pfam PF13185 GAF domain 287 428 1.1E-12 T 29-03-2018 IPR003018 GAF domain GO:0005515 CDC59_RS18360 080d7b7bbb1803cc92277f8f17c82041 649 SUPERFAMILY SSF55874 531 642 5.5E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS18360 080d7b7bbb1803cc92277f8f17c82041 649 SUPERFAMILY SSF55781 287 440 1.42E-16 T 29-03-2018 IPR029016 GAF domain-like CDC59_RS18360 080d7b7bbb1803cc92277f8f17c82041 649 SMART SM00304 200 252 4.6E-12 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CDC59_RS18360 080d7b7bbb1803cc92277f8f17c82041 649 SUPERFAMILY SSF158472 201 250 1.06E-9 T 29-03-2018 CDC59_RS18360 080d7b7bbb1803cc92277f8f17c82041 649 PIRSF PIRSF003167 11 649 8.1E-193 T 29-03-2018 IPR016380 Signal transduction histidine kinase, nitrate/nitrite-sensing GO:0000155|GO:0000160|GO:0004673|GO:0016021 CDC59_RS18360 080d7b7bbb1803cc92277f8f17c82041 649 Pfam PF13675 Type IV pili methyl-accepting chemotaxis transducer N-term 43 140 1.3E-20 T 29-03-2018 IPR029095 NarX-like, N-terminal CDC59_RS18360 080d7b7bbb1803cc92277f8f17c82041 649 SMART SM00387 550 645 2.3E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS18360 080d7b7bbb1803cc92277f8f17c82041 649 Pfam PF07730 Histidine kinase 444 510 2.9E-12 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CDC59_RS18360 080d7b7bbb1803cc92277f8f17c82041 649 Gene3D G3DSA:3.30.450.40 235 425 6.5E-27 T 29-03-2018 IPR029016 GAF domain-like CDC59_RS18360 080d7b7bbb1803cc92277f8f17c82041 649 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 558 644 8.7E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS18360 080d7b7bbb1803cc92277f8f17c82041 649 Pfam PF00672 HAMP domain 201 248 1.2E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CDC59_RS18360 080d7b7bbb1803cc92277f8f17c82041 649 Gene3D G3DSA:3.30.565.10 426 641 9.1E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS07190 b635255fcd3d811c078c9a9f08bc6d85 510 SUPERFAMILY SSF50249 15 156 2.45E-44 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDC59_RS07190 b635255fcd3d811c078c9a9f08bc6d85 510 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 18 508 3.0E-201 T 29-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CDC59_RS07190 b635255fcd3d811c078c9a9f08bc6d85 510 SUPERFAMILY SSF55681 163 507 7.82E-117 T 29-03-2018 CDC59_RS07190 b635255fcd3d811c078c9a9f08bc6d85 510 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 23 509 44.233 T 29-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CDC59_RS07190 b635255fcd3d811c078c9a9f08bc6d85 510 Gene3D G3DSA:3.30.930.10 157 506 7.6E-100 T 29-03-2018 CDC59_RS07190 b635255fcd3d811c078c9a9f08bc6d85 510 PRINTS PR00982 Lysyl-tRNA synthetase signature 263 280 4.2E-39 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CDC59_RS07190 b635255fcd3d811c078c9a9f08bc6d85 510 PRINTS PR00982 Lysyl-tRNA synthetase signature 216 232 4.2E-39 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CDC59_RS07190 b635255fcd3d811c078c9a9f08bc6d85 510 PRINTS PR00982 Lysyl-tRNA synthetase signature 391 407 4.2E-39 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CDC59_RS07190 b635255fcd3d811c078c9a9f08bc6d85 510 PRINTS PR00982 Lysyl-tRNA synthetase signature 200 210 4.2E-39 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CDC59_RS07190 b635255fcd3d811c078c9a9f08bc6d85 510 PRINTS PR00982 Lysyl-tRNA synthetase signature 245 258 4.2E-39 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CDC59_RS07190 b635255fcd3d811c078c9a9f08bc6d85 510 Pfam PF00152 tRNA synthetases class II (D, K and N) 163 506 5.4E-85 T 29-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDC59_RS07190 b635255fcd3d811c078c9a9f08bc6d85 510 Pfam PF01336 OB-fold nucleic acid binding domain 70 147 2.7E-15 T 29-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CDC59_RS07190 b635255fcd3d811c078c9a9f08bc6d85 510 Gene3D G3DSA:2.40.50.140 17 156 2.7E-40 T 29-03-2018 CDC59_RS14920 e86174d38f28a57aa24ed94c6f5ef3d9 393 SUPERFAMILY SSF56645 7 248 1.31E-87 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CDC59_RS14920 e86174d38f28a57aa24ed94c6f5ef3d9 393 Gene3D G3DSA:1.20.140.10 224 392 3.4E-52 T 29-03-2018 CDC59_RS14920 e86174d38f28a57aa24ed94c6f5ef3d9 393 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 235 388 5.3E-38 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CDC59_RS14920 e86174d38f28a57aa24ed94c6f5ef3d9 393 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 347 366 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CDC59_RS14920 e86174d38f28a57aa24ed94c6f5ef3d9 393 PIRSF PIRSF016578 13 111 0.0028 T 29-03-2018 CDC59_RS14920 e86174d38f28a57aa24ed94c6f5ef3d9 393 PIRSF PIRSF016578 133 392 5.6E-12 T 29-03-2018 CDC59_RS14920 e86174d38f28a57aa24ed94c6f5ef3d9 393 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 128 223 2.6E-27 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CDC59_RS14920 e86174d38f28a57aa24ed94c6f5ef3d9 393 Gene3D G3DSA:2.40.110.10 129 223 7.4E-42 T 29-03-2018 CDC59_RS14920 e86174d38f28a57aa24ed94c6f5ef3d9 393 Gene3D G3DSA:1.10.540.10 5 128 7.0E-41 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CDC59_RS14920 e86174d38f28a57aa24ed94c6f5ef3d9 393 SUPERFAMILY SSF47203 233 389 1.5E-43 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CDC59_RS14920 e86174d38f28a57aa24ed94c6f5ef3d9 393 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 130 142 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CDC59_RS14920 e86174d38f28a57aa24ed94c6f5ef3d9 393 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 13 124 6.1E-38 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CDC59_RS18225 00fc7051dfb04d0f3eef58067d8b6b50 130 Pfam PF01042 Endoribonuclease L-PSP 14 127 4.7E-33 T 29-03-2018 IPR006175 YjgF/YER057c/UK114 family CDC59_RS18225 00fc7051dfb04d0f3eef58067d8b6b50 130 SUPERFAMILY SSF55298 6 129 1.26E-39 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CDC59_RS18225 00fc7051dfb04d0f3eef58067d8b6b50 130 Gene3D G3DSA:3.30.1330.40 1 130 2.5E-37 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CDC59_RS19960 3a8a9a6c26b5d0741d0d6e128ad7febd 1051 Gene3D G3DSA:1.20.1640.10 828 1029 3.7E-33 T 29-03-2018 CDC59_RS19960 3a8a9a6c26b5d0741d0d6e128ad7febd 1051 Gene3D G3DSA:3.30.70.1440 673 769 2.8E-21 T 29-03-2018 CDC59_RS19960 3a8a9a6c26b5d0741d0d6e128ad7febd 1051 Pfam PF00873 AcrB/AcrD/AcrF family 1 1028 0.0 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS19960 3a8a9a6c26b5d0741d0d6e128ad7febd 1051 Gene3D G3DSA:3.30.70.1430 568 669 2.6E-19 T 29-03-2018 CDC59_RS19960 3a8a9a6c26b5d0741d0d6e128ad7febd 1051 SUPERFAMILY SSF82866 806 1031 1.57E-39 T 29-03-2018 CDC59_RS19960 3a8a9a6c26b5d0741d0d6e128ad7febd 1051 Gene3D G3DSA:3.30.70.1430 38 140 1.5E-28 T 29-03-2018 CDC59_RS19960 3a8a9a6c26b5d0741d0d6e128ad7febd 1051 Gene3D G3DSA:1.20.1640.10 286 510 7.9E-45 T 29-03-2018 CDC59_RS19960 3a8a9a6c26b5d0741d0d6e128ad7febd 1051 SUPERFAMILY SSF82693 566 670 2.93E-30 T 29-03-2018 CDC59_RS19960 3a8a9a6c26b5d0741d0d6e128ad7febd 1051 PRINTS PR00702 Acriflavin resistance protein family signature 363 384 1.6E-109 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS19960 3a8a9a6c26b5d0741d0d6e128ad7febd 1051 PRINTS PR00702 Acriflavin resistance protein family signature 470 493 1.6E-109 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS19960 3a8a9a6c26b5d0741d0d6e128ad7febd 1051 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 1.6E-109 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS19960 3a8a9a6c26b5d0741d0d6e128ad7febd 1051 PRINTS PR00702 Acriflavin resistance protein family signature 336 359 1.6E-109 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS19960 3a8a9a6c26b5d0741d0d6e128ad7febd 1051 PRINTS PR00702 Acriflavin resistance protein family signature 391 415 1.6E-109 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS19960 3a8a9a6c26b5d0741d0d6e128ad7febd 1051 PRINTS PR00702 Acriflavin resistance protein family signature 553 570 1.6E-109 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS19960 3a8a9a6c26b5d0741d0d6e128ad7febd 1051 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 1.6E-109 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS19960 3a8a9a6c26b5d0741d0d6e128ad7febd 1051 PRINTS PR00702 Acriflavin resistance protein family signature 445 468 1.6E-109 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS19960 3a8a9a6c26b5d0741d0d6e128ad7febd 1051 PRINTS PR00702 Acriflavin resistance protein family signature 622 636 1.6E-109 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS19960 3a8a9a6c26b5d0741d0d6e128ad7febd 1051 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 1 1043 0.0 T 29-03-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 CDC59_RS19960 3a8a9a6c26b5d0741d0d6e128ad7febd 1051 SUPERFAMILY SSF82866 296 497 5.49E-49 T 29-03-2018 CDC59_RS19960 3a8a9a6c26b5d0741d0d6e128ad7febd 1051 SUPERFAMILY SSF82693 136 182 1.03E-27 T 29-03-2018 CDC59_RS19960 3a8a9a6c26b5d0741d0d6e128ad7febd 1051 SUPERFAMILY SSF82693 274 330 1.03E-27 T 29-03-2018 CDC59_RS19960 3a8a9a6c26b5d0741d0d6e128ad7febd 1051 Gene3D G3DSA:3.30.2090.10 180 275 9.2E-21 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS19960 3a8a9a6c26b5d0741d0d6e128ad7febd 1051 SUPERFAMILY SSF82714 182 272 3.14E-22 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS19960 3a8a9a6c26b5d0741d0d6e128ad7febd 1051 SUPERFAMILY SSF82693 38 131 7.5E-27 T 29-03-2018 CDC59_RS19960 3a8a9a6c26b5d0741d0d6e128ad7febd 1051 SUPERFAMILY SSF82714 723 808 3.92E-22 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS09910 424d6611e06c11a0149a5164389de977 533 SMART SM00368 475 504 1.1 T 29-03-2018 CDC59_RS09910 424d6611e06c11a0149a5164389de977 533 SMART SM00368 211 240 9.4 T 29-03-2018 CDC59_RS09910 424d6611e06c11a0149a5164389de977 533 SMART SM00368 307 336 63.0 T 29-03-2018 CDC59_RS09910 424d6611e06c11a0149a5164389de977 533 SMART SM00368 427 450 24.0 T 29-03-2018 CDC59_RS09910 424d6611e06c11a0149a5164389de977 533 SMART SM00368 451 474 3.5 T 29-03-2018 CDC59_RS09910 424d6611e06c11a0149a5164389de977 533 SMART SM00368 259 288 9.3 T 29-03-2018 CDC59_RS09910 424d6611e06c11a0149a5164389de977 533 SMART SM00368 379 407 2.0 T 29-03-2018 CDC59_RS09910 424d6611e06c11a0149a5164389de977 533 SMART SM00368 187 210 94.0 T 29-03-2018 CDC59_RS09910 424d6611e06c11a0149a5164389de977 533 SMART SM00368 355 378 79.0 T 29-03-2018 CDC59_RS09910 424d6611e06c11a0149a5164389de977 533 Pfam PF13516 Leucine Rich repeat 379 399 4.3E-5 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS09910 424d6611e06c11a0149a5164389de977 533 Pfam PF13516 Leucine Rich repeat 355 377 0.39 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS09910 424d6611e06c11a0149a5164389de977 533 Pfam PF13516 Leucine Rich repeat 187 209 0.01 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS09910 424d6611e06c11a0149a5164389de977 533 Pfam PF13516 Leucine Rich repeat 307 329 1.2 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS09910 424d6611e06c11a0149a5164389de977 533 Pfam PF13516 Leucine Rich repeat 427 449 0.019 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS09910 424d6611e06c11a0149a5164389de977 533 Pfam PF13516 Leucine Rich repeat 451 473 2.7E-6 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS09910 424d6611e06c11a0149a5164389de977 533 Pfam PF13516 Leucine Rich repeat 331 352 6.1E-4 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS09910 424d6611e06c11a0149a5164389de977 533 Pfam PF13516 Leucine Rich repeat 213 232 0.074 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS09910 424d6611e06c11a0149a5164389de977 533 Pfam PF13516 Leucine Rich repeat 235 250 0.0032 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS09910 424d6611e06c11a0149a5164389de977 533 Pfam PF13516 Leucine Rich repeat 283 304 2.3E-4 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS09910 424d6611e06c11a0149a5164389de977 533 Pfam PF13516 Leucine Rich repeat 261 281 0.03 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS09910 424d6611e06c11a0149a5164389de977 533 SMART SM00367 138 164 150.0 T 29-03-2018 IPR006553 Leucine-rich repeat, cysteine-containing subtype CDC59_RS09910 424d6611e06c11a0149a5164389de977 533 SMART SM00367 211 235 230.0 T 29-03-2018 IPR006553 Leucine-rich repeat, cysteine-containing subtype CDC59_RS09910 424d6611e06c11a0149a5164389de977 533 SMART SM00367 308 331 360.0 T 29-03-2018 IPR006553 Leucine-rich repeat, cysteine-containing subtype CDC59_RS09910 424d6611e06c11a0149a5164389de977 533 SMART SM00367 283 307 7.3 T 29-03-2018 IPR006553 Leucine-rich repeat, cysteine-containing subtype CDC59_RS09910 424d6611e06c11a0149a5164389de977 533 SUPERFAMILY SSF52047 262 530 3.14E-54 T 29-03-2018 CDC59_RS09910 424d6611e06c11a0149a5164389de977 533 Gene3D G3DSA:3.80.10.10 465 527 6.8E-9 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like CDC59_RS09910 424d6611e06c11a0149a5164389de977 533 Gene3D G3DSA:3.80.10.10 414 464 4.3E-10 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like CDC59_RS09910 424d6611e06c11a0149a5164389de977 533 Gene3D G3DSA:3.80.10.10 267 320 3.6E-12 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like CDC59_RS09910 424d6611e06c11a0149a5164389de977 533 SUPERFAMILY SSF52058 115 315 7.94E-24 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like CDC59_RS09910 424d6611e06c11a0149a5164389de977 533 Gene3D G3DSA:3.80.10.10 54 266 2.4E-29 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like CDC59_RS09910 424d6611e06c11a0149a5164389de977 533 Gene3D G3DSA:3.80.10.10 321 413 1.1E-19 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like CDC59_RS01880 9b9d293ad4e87b7220b0b2732c08e451 293 Gene3D G3DSA:3.40.50.720 1 281 4.7E-59 T 29-03-2018 CDC59_RS01880 9b9d293ad4e87b7220b0b2732c08e451 293 SUPERFAMILY SSF51735 2 276 7.35E-65 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS01880 9b9d293ad4e87b7220b0b2732c08e451 293 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 193 5.7E-4 T 29-03-2018 CDC59_RS01880 9b9d293ad4e87b7220b0b2732c08e451 293 Pfam PF00106 short chain dehydrogenase 8 199 2.7E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS01880 9b9d293ad4e87b7220b0b2732c08e451 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 6.4E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS01880 9b9d293ad4e87b7220b0b2732c08e451 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 6.4E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS01880 9b9d293ad4e87b7220b0b2732c08e451 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 6.4E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS01880 9b9d293ad4e87b7220b0b2732c08e451 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 6.4E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS01880 9b9d293ad4e87b7220b0b2732c08e451 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 6.4E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS01880 9b9d293ad4e87b7220b0b2732c08e451 293 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CDC59_RS01880 9b9d293ad4e87b7220b0b2732c08e451 293 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 2.8E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS01880 9b9d293ad4e87b7220b0b2732c08e451 293 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 2.8E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS01880 9b9d293ad4e87b7220b0b2732c08e451 293 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 2.8E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS03810 00ba8b409736d69083ae038747a0f6c8 501 Gene3D G3DSA:3.40.309.10 284 475 6.9E-65 T 29-03-2018 CDC59_RS03810 00ba8b409736d69083ae038747a0f6c8 501 SUPERFAMILY SSF53720 16 496 2.23E-159 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CDC59_RS03810 00ba8b409736d69083ae038747a0f6c8 501 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 296 307 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CDC59_RS03810 00ba8b409736d69083ae038747a0f6c8 501 Gene3D G3DSA:3.40.605.10 7 283 7.7E-98 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CDC59_RS03810 00ba8b409736d69083ae038747a0f6c8 501 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 267 274 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CDC59_RS03810 00ba8b409736d69083ae038747a0f6c8 501 Pfam PF00171 Aldehyde dehydrogenase family 30 491 2.7E-164 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CDC59_RS04510 44258c89aa12c7540fd66a67de1ab5dd 461 SUPERFAMILY SSF53738 258 354 7.85E-32 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDC59_RS04510 44258c89aa12c7540fd66a67de1ab5dd 461 Gene3D G3DSA:3.30.310.50 369 461 1.2E-14 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDC59_RS04510 44258c89aa12c7540fd66a67de1ab5dd 461 SUPERFAMILY SSF53738 154 255 1.57E-32 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDC59_RS04510 44258c89aa12c7540fd66a67de1ab5dd 461 Gene3D G3DSA:3.40.120.10 153 260 1.7E-33 T 29-03-2018 CDC59_RS04510 44258c89aa12c7540fd66a67de1ab5dd 461 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 156 253 1.6E-26 T 29-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDC59_RS04510 44258c89aa12c7540fd66a67de1ab5dd 461 Gene3D G3DSA:3.40.120.10 2 152 4.7E-38 T 29-03-2018 CDC59_RS04510 44258c89aa12c7540fd66a67de1ab5dd 461 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 100 109 - T 29-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDC59_RS04510 44258c89aa12c7540fd66a67de1ab5dd 461 SUPERFAMILY SSF53738 3 177 1.37E-37 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDC59_RS04510 44258c89aa12c7540fd66a67de1ab5dd 461 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 233 248 2.2E-24 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDC59_RS04510 44258c89aa12c7540fd66a67de1ab5dd 461 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 204 217 2.2E-24 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDC59_RS04510 44258c89aa12c7540fd66a67de1ab5dd 461 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 170 189 2.2E-24 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDC59_RS04510 44258c89aa12c7540fd66a67de1ab5dd 461 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 99 113 2.2E-24 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDC59_RS04510 44258c89aa12c7540fd66a67de1ab5dd 461 SUPERFAMILY SSF55957 366 460 4.53E-21 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDC59_RS04510 44258c89aa12c7540fd66a67de1ab5dd 461 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 376 450 1.6E-11 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDC59_RS04510 44258c89aa12c7540fd66a67de1ab5dd 461 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 7 142 8.3E-33 T 29-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDC59_RS04510 44258c89aa12c7540fd66a67de1ab5dd 461 Gene3D G3DSA:3.40.120.10 261 367 3.4E-24 T 29-03-2018 CDC59_RS04510 44258c89aa12c7540fd66a67de1ab5dd 461 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 258 365 7.7E-21 T 29-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDC59_RS10290 a69764d735d1307b19b6ecb9d44c891f 403 Gene3D G3DSA:3.90.1150.10 264 401 1.3E-35 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS10290 a69764d735d1307b19b6ecb9d44c891f 403 PIRSF PIRSF001434 2 400 4.6E-119 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CDC59_RS10290 a69764d735d1307b19b6ecb9d44c891f 403 TIGRFAM TIGR01324 cysta_beta_ly_B: cystathionine beta-lyase 34 399 2.1E-118 T 29-03-2018 IPR006233 Cystathionine beta-lyase, bacterial GO:0004121|GO:0005737|GO:0006520 KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 CDC59_RS10290 a69764d735d1307b19b6ecb9d44c891f 403 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 14 398 2.0E-88 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CDC59_RS10290 a69764d735d1307b19b6ecb9d44c891f 403 Gene3D G3DSA:3.40.640.10 11 263 2.3E-44 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDC59_RS10290 a69764d735d1307b19b6ecb9d44c891f 403 SUPERFAMILY SSF53383 36 398 3.3E-91 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS07600 1614927507b6bd0734e8f6e466ca4ebc 244 Gene3D G3DSA:3.40.30.10 14 209 4.8E-14 T 29-03-2018 CDC59_RS07600 1614927507b6bd0734e8f6e466ca4ebc 244 SUPERFAMILY SSF52833 51 153 8.96E-8 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS07600 1614927507b6bd0734e8f6e466ca4ebc 244 Pfam PF05988 Bacterial protein of unknown function (DUF899) 1 232 2.6E-92 T 29-03-2018 IPR010296 Protein of unknown function DUF899, thioredoxin-like CDC59_RS02885 48c643cf091c48e1bea831733cd06c49 737 Pfam PF13515 Fusaric acid resistance protein-like 403 524 2.2E-16 T 29-03-2018 CDC59_RS02885 48c643cf091c48e1bea831733cd06c49 737 Pfam PF12805 FUSC-like inner membrane protein yccS 69 336 9.0E-60 T 29-03-2018 IPR032692 Integral membrane protein YccS, N-terminal CDC59_RS12895 c6462f4897cf225190461fd20e21d7e8 197 Gene3D G3DSA:2.60.120.10 110 193 8.8E-17 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CDC59_RS12895 c6462f4897cf225190461fd20e21d7e8 197 Pfam PF05962 HutD 8 176 3.3E-49 T 29-03-2018 IPR010282 Uncharacterised protein family HutD/Ves CDC59_RS12895 c6462f4897cf225190461fd20e21d7e8 197 Gene3D G3DSA:2.60.120.10 7 109 6.0E-34 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CDC59_RS12895 c6462f4897cf225190461fd20e21d7e8 197 SUPERFAMILY SSF51182 2 182 1.07E-46 T 29-03-2018 IPR011051 RmlC-like cupin domain CDC59_RS13620 2f928a6cc70271a81f2fd8992e8e46cc 250 Gene3D G3DSA:3.40.1130.10 25 249 7.4E-37 T 29-03-2018 CDC59_RS13620 2f928a6cc70271a81f2fd8992e8e46cc 250 SUPERFAMILY SSF69593 6 249 4.97E-40 T 29-03-2018 CDC59_RS13620 2f928a6cc70271a81f2fd8992e8e46cc 250 Pfam PF01553 Acyltransferase 66 190 3.4E-18 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CDC59_RS13620 2f928a6cc70271a81f2fd8992e8e46cc 250 SMART SM00563 77 193 6.8E-24 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CDC59_RS03560 af9ec598562eef4fc25a3e54966ad852 143 Pfam PF01475 Ferric uptake regulator family 10 129 5.1E-45 T 29-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CDC59_RS03560 af9ec598562eef4fc25a3e54966ad852 143 Gene3D G3DSA:1.10.10.10 4 89 1.0E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS03560 af9ec598562eef4fc25a3e54966ad852 143 SUPERFAMILY SSF46785 6 133 6.73E-41 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS14870 f4d9e73d6ad64735bd0ad23f2f23e0f9 475 SMART SM00387 352 448 6.3E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS14870 f4d9e73d6ad64735bd0ad23f2f23e0f9 475 Gene3D G3DSA:3.30.565.10 209 447 2.2E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS14870 f4d9e73d6ad64735bd0ad23f2f23e0f9 475 Pfam PF05227 CHASE3 domain 37 164 4.7E-29 T 29-03-2018 IPR007891 CHASE3 CDC59_RS14870 f4d9e73d6ad64735bd0ad23f2f23e0f9 475 Pfam PF07730 Histidine kinase 247 313 2.6E-14 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CDC59_RS14870 f4d9e73d6ad64735bd0ad23f2f23e0f9 475 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 355 447 4.2E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS14870 f4d9e73d6ad64735bd0ad23f2f23e0f9 475 SUPERFAMILY SSF55874 339 446 1.83E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS16345 18b23cfd6ee7228e3620b4be47fefeac 260 Pfam PF03988 Repeat of Unknown Function (DUF347) 196 246 1.9E-15 T 29-03-2018 IPR007136 Protein of unknown function DUF347 CDC59_RS16345 18b23cfd6ee7228e3620b4be47fefeac 260 Pfam PF03988 Repeat of Unknown Function (DUF347) 77 128 2.5E-13 T 29-03-2018 IPR007136 Protein of unknown function DUF347 CDC59_RS16345 18b23cfd6ee7228e3620b4be47fefeac 260 Pfam PF03988 Repeat of Unknown Function (DUF347) 23 73 5.6E-15 T 29-03-2018 IPR007136 Protein of unknown function DUF347 CDC59_RS16345 18b23cfd6ee7228e3620b4be47fefeac 260 Pfam PF03988 Repeat of Unknown Function (DUF347) 142 188 1.0E-9 T 29-03-2018 IPR007136 Protein of unknown function DUF347 CDC59_RS00940 903cbee5629a3d39828191f3cf326f27 381 SUPERFAMILY SSF53822 27 375 1.32E-90 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CDC59_RS00940 903cbee5629a3d39828191f3cf326f27 381 Gene3D G3DSA:3.40.50.2300 289 369 1.9E-5 T 29-03-2018 CDC59_RS00940 903cbee5629a3d39828191f3cf326f27 381 Gene3D G3DSA:3.40.50.2300 158 288 1.8E-37 T 29-03-2018 CDC59_RS00940 903cbee5629a3d39828191f3cf326f27 381 Gene3D G3DSA:3.40.50.2300 27 157 4.2E-18 T 29-03-2018 CDC59_RS00940 903cbee5629a3d39828191f3cf326f27 381 Pfam PF13458 Periplasmic binding protein 29 371 5.5E-59 T 29-03-2018 IPR028081 Leucine-binding protein domain CDC59_RS03740 408d8a2c8420c868b8c80044fea3dbaa 730 Gene3D G3DSA:3.40.50.300 495 667 9.9E-30 T 29-03-2018 CDC59_RS03740 408d8a2c8420c868b8c80044fea3dbaa 730 SUPERFAMILY SSF50249 44 199 6.34E-22 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDC59_RS03740 408d8a2c8420c868b8c80044fea3dbaa 730 Pfam PF00271 Helicase conserved C-terminal domain 515 625 9.0E-17 T 29-03-2018 IPR001650 Helicase, C-terminal CDC59_RS03740 408d8a2c8420c868b8c80044fea3dbaa 730 SMART SM00490 542 626 3.9E-18 T 29-03-2018 IPR001650 Helicase, C-terminal CDC59_RS03740 408d8a2c8420c868b8c80044fea3dbaa 730 Gene3D G3DSA:3.40.50.300 283 494 1.4E-35 T 29-03-2018 CDC59_RS03740 408d8a2c8420c868b8c80044fea3dbaa 730 SUPERFAMILY SSF52540 490 692 1.03E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS03740 408d8a2c8420c868b8c80044fea3dbaa 730 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 57 701 3.4E-208 T 29-03-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 CDC59_RS03740 408d8a2c8420c868b8c80044fea3dbaa 730 Gene3D G3DSA:2.40.50.140 75 168 2.8E-5 T 29-03-2018 CDC59_RS03740 408d8a2c8420c868b8c80044fea3dbaa 730 SMART SM00487 295 497 4.9E-29 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CDC59_RS03740 408d8a2c8420c868b8c80044fea3dbaa 730 Pfam PF17191 RecG wedge domain 45 194 2.2E-9 T 29-03-2018 IPR033454 RecG, wedge domain CDC59_RS03740 408d8a2c8420c868b8c80044fea3dbaa 730 SUPERFAMILY SSF52540 240 491 1.05E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS03740 408d8a2c8420c868b8c80044fea3dbaa 730 Pfam PF00270 DEAD/DEAH box helicase 320 471 9.1E-16 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CDC59_RS21525 6ad699c8cfde51518c5c128176acd96a 695 SUPERFAMILY SSF55073 271 429 5.65E-40 T 29-03-2018 IPR029787 Nucleotide cyclase CDC59_RS21525 6ad699c8cfde51518c5c128176acd96a 695 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 268 425 1.7E-28 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS21525 6ad699c8cfde51518c5c128176acd96a 695 SMART SM00052 437 684 4.7E-113 T 29-03-2018 IPR001633 EAL domain CDC59_RS21525 6ad699c8cfde51518c5c128176acd96a 695 Pfam PF00563 EAL domain 443 679 1.1E-74 T 29-03-2018 IPR001633 EAL domain CDC59_RS21525 6ad699c8cfde51518c5c128176acd96a 695 Gene3D G3DSA:3.20.20.450 435 688 4.0E-98 T 29-03-2018 IPR001633 EAL domain CDC59_RS21525 6ad699c8cfde51518c5c128176acd96a 695 Gene3D G3DSA:3.30.70.270 267 434 5.4E-51 T 29-03-2018 CDC59_RS21525 6ad699c8cfde51518c5c128176acd96a 695 SUPERFAMILY SSF141868 443 689 1.31E-88 T 29-03-2018 IPR001633 EAL domain CDC59_RS21525 6ad699c8cfde51518c5c128176acd96a 695 Pfam PF00990 Diguanylate cyclase, GGDEF domain 268 422 6.9E-37 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS21525 6ad699c8cfde51518c5c128176acd96a 695 SMART SM00267 251 427 1.9E-46 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS08045 c65f58b8cca7711f373c0868ef9c7579 115 Pfam PF02575 YbaB/EbfC DNA-binding family 10 100 5.3E-35 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CDC59_RS08045 c65f58b8cca7711f373c0868ef9c7579 115 PIRSF PIRSF004555 2 115 4.7E-37 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CDC59_RS08045 c65f58b8cca7711f373c0868ef9c7579 115 SUPERFAMILY SSF82607 7 99 2.75E-33 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CDC59_RS08045 c65f58b8cca7711f373c0868ef9c7579 115 Gene3D G3DSA:3.30.1310.10 1 115 1.5E-38 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CDC59_RS08045 c65f58b8cca7711f373c0868ef9c7579 115 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 4 99 22.722 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CDC59_RS08045 c65f58b8cca7711f373c0868ef9c7579 115 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 3 106 2.0E-30 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CDC59_RS15790 9e4fb62738a1d4a4d45b6f2db863d32f 403 Gene3D G3DSA:3.40.50.450 137 289 1.9E-37 T 29-03-2018 CDC59_RS15790 9e4fb62738a1d4a4d45b6f2db863d32f 403 Gene3D G3DSA:1.10.150.20 43 81 0.0023 T 29-03-2018 CDC59_RS15790 9e4fb62738a1d4a4d45b6f2db863d32f 403 SUPERFAMILY SSF102405 106 312 1.68E-42 T 29-03-2018 CDC59_RS15790 9e4fb62738a1d4a4d45b6f2db863d32f 403 Gene3D G3DSA:1.10.10.10 320 402 2.7E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS15790 9e4fb62738a1d4a4d45b6f2db863d32f 403 SUPERFAMILY SSF47781 27 79 1.71E-6 T 29-03-2018 IPR010994 RuvA domain 2-like CDC59_RS15790 9e4fb62738a1d4a4d45b6f2db863d32f 403 Pfam PF02481 DNA recombination-mediator protein A 101 303 5.7E-75 T 29-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 CDC59_RS15790 9e4fb62738a1d4a4d45b6f2db863d32f 403 Gene3D G3DSA:1.10.150.20 6 42 0.0015 T 29-03-2018 CDC59_RS15790 9e4fb62738a1d4a4d45b6f2db863d32f 403 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 95 312 4.0E-75 T 29-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 CDC59_RS11585 0b5c4002366402b6c0db8fe54a59eeb0 361 Gene3D G3DSA:3.90.1200.10 126 317 3.9E-33 T 29-03-2018 CDC59_RS11585 0b5c4002366402b6c0db8fe54a59eeb0 361 Pfam PF01636 Phosphotransferase enzyme family 43 273 3.2E-55 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase CDC59_RS11585 0b5c4002366402b6c0db8fe54a59eeb0 361 SUPERFAMILY SSF56112 21 355 2.12E-59 T 29-03-2018 IPR011009 Protein kinase-like domain CDC59_RS11585 0b5c4002366402b6c0db8fe54a59eeb0 361 Gene3D G3DSA:3.30.200.20 20 125 4.1E-32 T 29-03-2018 CDC59_RS10930 26341738703cb11e2e14f7ea641b38fa 447 SUPERFAMILY SSF53738 263 370 3.53E-28 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDC59_RS10930 26341738703cb11e2e14f7ea641b38fa 447 SUPERFAMILY SSF53738 2 186 1.61E-48 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDC59_RS10930 26341738703cb11e2e14f7ea641b38fa 447 SUPERFAMILY SSF55957 363 446 2.35E-21 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDC59_RS10930 26341738703cb11e2e14f7ea641b38fa 447 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 101 110 - T 29-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDC59_RS10930 26341738703cb11e2e14f7ea641b38fa 447 Gene3D G3DSA:3.30.310.50 379 447 9.5E-21 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDC59_RS10930 26341738703cb11e2e14f7ea641b38fa 447 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 144 7.0E-42 T 29-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDC59_RS10930 26341738703cb11e2e14f7ea641b38fa 447 Gene3D G3DSA:3.40.120.10 161 270 3.9E-30 T 29-03-2018 CDC59_RS10930 26341738703cb11e2e14f7ea641b38fa 447 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 6 446 2.1E-178 T 29-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDC59_RS10930 26341738703cb11e2e14f7ea641b38fa 447 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 239 254 4.4E-14 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDC59_RS10930 26341738703cb11e2e14f7ea641b38fa 447 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 100 114 4.4E-14 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDC59_RS10930 26341738703cb11e2e14f7ea641b38fa 447 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 179 198 4.4E-14 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDC59_RS10930 26341738703cb11e2e14f7ea641b38fa 447 Gene3D G3DSA:3.40.120.10 271 378 1.2E-27 T 29-03-2018 CDC59_RS10930 26341738703cb11e2e14f7ea641b38fa 447 Gene3D G3DSA:3.40.120.10 2 159 1.7E-50 T 29-03-2018 CDC59_RS10930 26341738703cb11e2e14f7ea641b38fa 447 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 162 259 2.3E-18 T 29-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDC59_RS10930 26341738703cb11e2e14f7ea641b38fa 447 SUPERFAMILY SSF53738 161 261 1.18E-28 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDC59_RS10930 26341738703cb11e2e14f7ea641b38fa 447 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 378 446 1.3E-15 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDC59_RS10930 26341738703cb11e2e14f7ea641b38fa 447 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 2 445 45.801 T 29-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDC59_RS10930 26341738703cb11e2e14f7ea641b38fa 447 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 263 370 8.6E-32 T 29-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CDC59_RS11890 9ba552e1583fd8e8b36ba9b809624af5 188 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 9 181 2.2E-20 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS11890 9ba552e1583fd8e8b36ba9b809624af5 188 SUPERFAMILY SSF88946 6 82 4.71E-8 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS11890 9ba552e1583fd8e8b36ba9b809624af5 188 SUPERFAMILY SSF88659 117 181 6.35E-17 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS11890 9ba552e1583fd8e8b36ba9b809624af5 188 Gene3D G3DSA:1.10.1740.10 2 117 4.9E-8 T 29-03-2018 CDC59_RS11890 9ba552e1583fd8e8b36ba9b809624af5 188 Gene3D G3DSA:1.10.10.10 118 187 1.2E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS11890 9ba552e1583fd8e8b36ba9b809624af5 188 Pfam PF08281 Sigma-70, region 4 125 173 2.0E-17 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS03515 5253a53bc5e5d82e9235289b26ade2c8 781 SMART SM01274 39 172 4.4E-77 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CDC59_RS03515 5253a53bc5e5d82e9235289b26ade2c8 781 Pfam PF03949 Malic enzyme, NAD binding domain 186 381 3.2E-22 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CDC59_RS03515 5253a53bc5e5d82e9235289b26ade2c8 781 Pfam PF12434 Malate dehydrogenase enzyme 5 37 6.8E-18 T 29-03-2018 IPR032683 Malate dehydrogenase enzyme, N-terminal CDC59_RS03515 5253a53bc5e5d82e9235289b26ade2c8 781 SMART SM00919 184 421 6.0E-140 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CDC59_RS03515 5253a53bc5e5d82e9235289b26ade2c8 781 PRINTS PR00072 Malic enzyme signature 101 123 4.4E-5 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CDC59_RS03515 5253a53bc5e5d82e9235289b26ade2c8 781 PRINTS PR00072 Malic enzyme signature 211 227 4.4E-5 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CDC59_RS03515 5253a53bc5e5d82e9235289b26ade2c8 781 PRINTS PR00072 Malic enzyme signature 180 196 4.4E-5 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CDC59_RS03515 5253a53bc5e5d82e9235289b26ade2c8 781 Gene3D G3DSA:3.40.718.10 470 743 7.0E-53 T 29-03-2018 CDC59_RS03515 5253a53bc5e5d82e9235289b26ade2c8 781 Gene3D G3DSA:3.40.50.720 182 469 9.2E-86 T 29-03-2018 CDC59_RS03515 5253a53bc5e5d82e9235289b26ade2c8 781 SUPERFAMILY SSF51735 184 461 5.26E-88 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS03515 5253a53bc5e5d82e9235289b26ade2c8 781 Pfam PF00390 Malic enzyme, N-terminal domain 40 172 3.7E-25 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CDC59_RS03515 5253a53bc5e5d82e9235289b26ade2c8 781 SUPERFAMILY SSF53223 31 182 1.65E-51 T 29-03-2018 CDC59_RS03515 5253a53bc5e5d82e9235289b26ade2c8 781 PIRSF PIRSF036684 19 780 0.0 T 29-03-2018 IPR012188 NAD(P)-dependent malic enzyme GO:0004470|GO:0006108|GO:0046872 KEGG: 00620+1.1.1.40|KEGG: 00710+1.1.1.40|MetaCyc: PWY-241|MetaCyc: PWY-7117 CDC59_RS03515 5253a53bc5e5d82e9235289b26ade2c8 781 SUPERFAMILY SSF53659 450 775 4.52E-91 T 29-03-2018 CDC59_RS03515 5253a53bc5e5d82e9235289b26ade2c8 781 Gene3D G3DSA:3.40.50.10380 26 181 9.7E-35 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CDC59_RS03515 5253a53bc5e5d82e9235289b26ade2c8 781 Pfam PF01515 Phosphate acetyl/butaryl transferase 450 772 1.7E-99 T 29-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CDC59_RS09265 0652d434ec300031d4dcecf580b7558e 148 SUPERFAMILY SSF74982 2 127 7.72E-51 T 29-03-2018 IPR023620 Small protein B CDC59_RS09265 0652d434ec300031d4dcecf580b7558e 148 Gene3D G3DSA:2.40.280.10 3 122 2.9E-48 T 29-03-2018 IPR023620 Small protein B CDC59_RS09265 0652d434ec300031d4dcecf580b7558e 148 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 3 127 3.0E-66 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 CDC59_RS09265 0652d434ec300031d4dcecf580b7558e 148 TIGRFAM TIGR00086 smpB: SsrA-binding protein 3 144 1.4E-54 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 CDC59_RS09265 0652d434ec300031d4dcecf580b7558e 148 Hamap MF_00023 SsrA-binding protein [smpB]. 1 148 75.151 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 CDC59_RS09265 0652d434ec300031d4dcecf580b7558e 148 ProSitePatterns PS01317 SsrA-binding protein. 21 33 - T 29-03-2018 IPR020081 SsrA-binding protein, conserved site CDC59_RS09265 0652d434ec300031d4dcecf580b7558e 148 Pfam PF01668 SmpB protein 3 145 6.2E-60 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 CDC59_RS09190 ac70dc9a53b6ca6805711599c4f091b4 755 PIRSF PIRSF006076 1 755 5.4E-258 T 29-03-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 CDC59_RS09190 ac70dc9a53b6ca6805711599c4f091b4 755 Gene3D G3DSA:3.10.20.310 14 87 1.7E-12 T 29-03-2018 CDC59_RS09190 ac70dc9a53b6ca6805711599c4f091b4 755 Gene3D G3DSA:3.10.20.310 171 262 4.5E-23 T 29-03-2018 CDC59_RS09190 ac70dc9a53b6ca6805711599c4f091b4 755 Hamap MF_01430 Outer membrane protein assembly factor BamA [bamA]. 2 755 25.522 T 29-03-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 CDC59_RS09190 ac70dc9a53b6ca6805711599c4f091b4 755 TIGRFAM TIGR03303 OM_YaeT: outer membrane protein assembly complex, YaeT protein 20 755 2.0E-277 T 29-03-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 CDC59_RS09190 ac70dc9a53b6ca6805711599c4f091b4 755 Pfam PF01103 Surface antigen 444 755 2.8E-82 T 29-03-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 CDC59_RS09190 ac70dc9a53b6ca6805711599c4f091b4 755 Gene3D G3DSA:3.10.20.310 263 342 2.4E-15 T 29-03-2018 CDC59_RS09190 ac70dc9a53b6ca6805711599c4f091b4 755 Gene3D G3DSA:2.40.160.50 376 755 6.9E-84 T 29-03-2018 CDC59_RS09190 ac70dc9a53b6ca6805711599c4f091b4 755 Gene3D G3DSA:3.10.20.310 88 170 1.4E-16 T 29-03-2018 CDC59_RS09190 ac70dc9a53b6ca6805711599c4f091b4 755 Pfam PF07244 Surface antigen variable number repeat 21 87 7.9E-6 T 29-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 CDC59_RS09190 ac70dc9a53b6ca6805711599c4f091b4 755 Pfam PF07244 Surface antigen variable number repeat 262 340 1.3E-13 T 29-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 CDC59_RS09190 ac70dc9a53b6ca6805711599c4f091b4 755 Pfam PF07244 Surface antigen variable number repeat 89 168 6.5E-14 T 29-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 CDC59_RS09190 ac70dc9a53b6ca6805711599c4f091b4 755 Pfam PF07244 Surface antigen variable number repeat 172 259 1.2E-19 T 29-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 CDC59_RS09190 ac70dc9a53b6ca6805711599c4f091b4 755 Pfam PF07244 Surface antigen variable number repeat 343 417 5.0E-13 T 29-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 CDC59_RS06735 ed0a411b23b8acb8884d834b55b8c0ff 128 Pfam PF01245 Ribosomal protein L19 2 117 2.4E-47 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS06735 ed0a411b23b8acb8884d834b55b8c0ff 128 SUPERFAMILY SSF50104 1 119 1.3E-45 T 29-03-2018 IPR008991 Translation protein SH3-like domain CDC59_RS06735 ed0a411b23b8acb8884d834b55b8c0ff 128 PIRSF PIRSF002191 1 128 3.1E-52 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS06735 ed0a411b23b8acb8884d834b55b8c0ff 128 PRINTS PR00061 Ribosomal protein L19 signature 38 67 1.2E-34 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS06735 ed0a411b23b8acb8884d834b55b8c0ff 128 PRINTS PR00061 Ribosomal protein L19 signature 92 117 1.2E-34 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS06735 ed0a411b23b8acb8884d834b55b8c0ff 128 PRINTS PR00061 Ribosomal protein L19 signature 8 37 1.2E-34 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS06735 ed0a411b23b8acb8884d834b55b8c0ff 128 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 1 117 2.5E-49 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS06735 ed0a411b23b8acb8884d834b55b8c0ff 128 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 1 118 30.878 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS06735 ed0a411b23b8acb8884d834b55b8c0ff 128 ProSitePatterns PS01015 Ribosomal protein L19 signature. 90 105 - T 29-03-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS12500 a07b2187ceff5a642015dd0eef6d26cd 600 SUPERFAMILY SSF81340 4 432 4.32E-93 T 29-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 CDC59_RS12500 a07b2187ceff5a642015dd0eef6d26cd 600 PRINTS PR00762 Chloride channel signature 360 376 9.4E-14 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CDC59_RS12500 a07b2187ceff5a642015dd0eef6d26cd 600 PRINTS PR00762 Chloride channel signature 118 137 9.4E-14 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CDC59_RS12500 a07b2187ceff5a642015dd0eef6d26cd 600 PRINTS PR00762 Chloride channel signature 169 188 9.4E-14 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CDC59_RS12500 a07b2187ceff5a642015dd0eef6d26cd 600 PRINTS PR00762 Chloride channel signature 378 397 9.4E-14 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CDC59_RS12500 a07b2187ceff5a642015dd0eef6d26cd 600 Pfam PF00571 CBS domain 443 495 0.0032 T 29-03-2018 IPR000644 CBS domain CDC59_RS12500 a07b2187ceff5a642015dd0eef6d26cd 600 Pfam PF00571 CBS domain 514 560 6.4E-5 T 29-03-2018 IPR000644 CBS domain CDC59_RS12500 a07b2187ceff5a642015dd0eef6d26cd 600 Gene3D G3DSA:3.10.580.10 437 564 3.1E-15 T 29-03-2018 CDC59_RS12500 a07b2187ceff5a642015dd0eef6d26cd 600 Pfam PF00654 Voltage gated chloride channel 75 407 5.0E-70 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CDC59_RS12500 a07b2187ceff5a642015dd0eef6d26cd 600 Gene3D G3DSA:1.10.3080.10 1 434 9.7E-72 T 29-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 CDC59_RS12500 a07b2187ceff5a642015dd0eef6d26cd 600 SUPERFAMILY SSF54631 435 560 2.44E-15 T 29-03-2018 CDC59_RS12500 a07b2187ceff5a642015dd0eef6d26cd 600 SMART SM00116 447 499 81.0 T 29-03-2018 IPR000644 CBS domain CDC59_RS12500 a07b2187ceff5a642015dd0eef6d26cd 600 SMART SM00116 513 563 2.3E-5 T 29-03-2018 IPR000644 CBS domain CDC59_RS08255 92e691eaf86f0596fc97fd71d7e061ce 502 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 30 477 3.3E-113 T 29-03-2018 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 CDC59_RS08255 92e691eaf86f0596fc97fd71d7e061ce 502 TIGRFAM TIGR00800 ncs1: NCS1 nucleoside transporter family 22 451 4.0E-111 T 29-03-2018 IPR012681 Nucleobase cation symporter-1, NCS1 GO:0005215|GO:0006810|GO:0016020 CDC59_RS10265 0766b278365fe83a75d9ef123bb35d23 253 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 10 241 42.381 T 29-03-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CDC59_RS10265 0766b278365fe83a75d9ef123bb35d23 253 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 114 121 - T 29-03-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CDC59_RS10265 0766b278365fe83a75d9ef123bb35d23 253 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 13 241 2.1E-65 T 29-03-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CDC59_RS10265 0766b278365fe83a75d9ef123bb35d23 253 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 13 242 4.7E-64 T 29-03-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CDC59_RS10265 0766b278365fe83a75d9ef123bb35d23 253 Gene3D G3DSA:3.90.550.10 4 248 4.3E-47 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDC59_RS10265 0766b278365fe83a75d9ef123bb35d23 253 SUPERFAMILY SSF53448 12 241 9.75E-58 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDC59_RS13915 2603e6e2c18d08fbe83ba13829af1cfd 157 SUPERFAMILY SSF55811 5 146 6.91E-24 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CDC59_RS13915 2603e6e2c18d08fbe83ba13829af1cfd 157 Gene3D G3DSA:3.90.79.10 1 147 3.1E-28 T 29-03-2018 CDC59_RS13915 2603e6e2c18d08fbe83ba13829af1cfd 157 PRINTS PR01404 DATP pyrophosphohydrolase signature 19 40 6.9E-14 T 29-03-2018 IPR003564 Dihydroneopterin triphosphate diphosphatase GO:0008828|GO:0019177|GO:0046656 KEGG: 00790+3.6.1.67|MetaCyc: PWY-6147 CDC59_RS13915 2603e6e2c18d08fbe83ba13829af1cfd 157 PRINTS PR01404 DATP pyrophosphohydrolase signature 69 88 6.9E-14 T 29-03-2018 IPR003564 Dihydroneopterin triphosphate diphosphatase GO:0008828|GO:0019177|GO:0046656 KEGG: 00790+3.6.1.67|MetaCyc: PWY-6147 CDC59_RS13915 2603e6e2c18d08fbe83ba13829af1cfd 157 PRINTS PR01404 DATP pyrophosphohydrolase signature 126 139 6.9E-14 T 29-03-2018 IPR003564 Dihydroneopterin triphosphate diphosphatase GO:0008828|GO:0019177|GO:0046656 KEGG: 00790+3.6.1.67|MetaCyc: PWY-6147 CDC59_RS13915 2603e6e2c18d08fbe83ba13829af1cfd 157 Pfam PF00293 NUDIX domain 6 130 9.5E-17 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CDC59_RS18845 548c21461c68db82a0b5807b928508b2 107 SUPERFAMILY SSF54913 2 102 5.08E-18 T 29-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta CDC59_RS18845 548c21461c68db82a0b5807b928508b2 107 Gene3D G3DSA:3.30.70.120 1 103 1.1E-18 T 29-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CDC59_RS18845 548c21461c68db82a0b5807b928508b2 107 SMART SM00938 4 107 1.6E-5 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CDC59_RS18845 548c21461c68db82a0b5807b928508b2 107 Pfam PF00543 Nitrogen regulatory protein P-II 4 107 1.9E-22 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CDC59_RS18845 548c21461c68db82a0b5807b928508b2 107 PRINTS PR00340 P-II protein signature 84 104 2.7E-9 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CDC59_RS18845 548c21461c68db82a0b5807b928508b2 107 PRINTS PR00340 P-II protein signature 53 76 2.7E-9 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CDC59_RS18845 548c21461c68db82a0b5807b928508b2 107 PRINTS PR00340 P-II protein signature 2 17 2.7E-9 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CDC59_RS03035 bca71150eed9f4795fe5a01c71be5d6e 573 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 228 566 4.0E-136 T 29-03-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 CDC59_RS03035 bca71150eed9f4795fe5a01c71be5d6e 573 SUPERFAMILY SSF52794 4 99 4.71E-12 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CDC59_RS03035 bca71150eed9f4795fe5a01c71be5d6e 573 Gene3D G3DSA:3.40.50.2300 3 99 8.0E-12 T 29-03-2018 CDC59_RS03035 bca71150eed9f4795fe5a01c71be5d6e 573 Gene3D G3DSA:3.40.50.2300 112 209 1.7E-38 T 29-03-2018 CDC59_RS03035 bca71150eed9f4795fe5a01c71be5d6e 573 SUPERFAMILY SSF52794 112 211 6.28E-36 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CDC59_RS03035 bca71150eed9f4795fe5a01c71be5d6e 573 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 114 196 4.6E-33 T 29-03-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202|KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 CDC59_RS03035 bca71150eed9f4795fe5a01c71be5d6e 573 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 115 203 2.2E-17 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CDC59_RS00665 805103d042843d3f3c5e6c506116855c 257 Pfam PF07947 YhhN family 64 241 4.6E-44 T 29-03-2018 IPR012506 YhhN-like GO:0016021 CDC59_RS04570 a8ef1066be1b6fdbe8cb500ee971dc4e 370 Gene3D G3DSA:3.20.20.70 1 361 4.0E-114 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS04570 a8ef1066be1b6fdbe8cb500ee971dc4e 370 SUPERFAMILY SSF51395 1 355 5.19E-111 T 29-03-2018 CDC59_RS04570 a8ef1066be1b6fdbe8cb500ee971dc4e 370 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 334 8.1E-63 T 29-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CDC59_RS00405 15692cb48717a617ec6fccede97f2b64 266 SUPERFAMILY SSF53474 18 260 1.2E-39 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS00405 15692cb48717a617ec6fccede97f2b64 266 Gene3D G3DSA:3.40.50.1820 7 262 5.6E-37 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS00405 15692cb48717a617ec6fccede97f2b64 266 Pfam PF12697 Alpha/beta hydrolase family 34 252 6.8E-15 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS05525 7d1f30c45cbc18ec2b9590ea6d3492d8 105 Gene3D G3DSA:1.10.150.20 8 40 2.1E-7 T 29-03-2018 CDC59_RS05525 7d1f30c45cbc18ec2b9590ea6d3492d8 105 Pfam PF12836 Helix-hairpin-helix motif 21 79 6.1E-16 T 29-03-2018 CDC59_RS05525 7d1f30c45cbc18ec2b9590ea6d3492d8 105 SUPERFAMILY SSF47781 21 81 2.11E-20 T 29-03-2018 IPR010994 RuvA domain 2-like CDC59_RS05525 7d1f30c45cbc18ec2b9590ea6d3492d8 105 Gene3D G3DSA:1.10.150.310 41 93 9.9E-12 T 29-03-2018 CDC59_RS17305 98525d3e60b32b2b4a1812da0b914ebf 146 Pfam PF02195 ParB-like nuclease domain 19 79 3.4E-7 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CDC59_RS17305 98525d3e60b32b2b4a1812da0b914ebf 146 SUPERFAMILY SSF110849 7 134 3.66E-36 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CDC59_RS17305 98525d3e60b32b2b4a1812da0b914ebf 146 Gene3D G3DSA:3.90.1530.10 11 92 6.2E-11 T 29-03-2018 CDC59_RS11035 01e4e5ed2c7906f028bd05c35d38243f 151 Pfam PF00582 Universal stress protein family 1 144 9.5E-30 T 29-03-2018 IPR006016 UspA GO:0006950 CDC59_RS11035 01e4e5ed2c7906f028bd05c35d38243f 151 PRINTS PR01438 Universal stress protein signature 106 118 3.2E-17 T 29-03-2018 IPR006015 Universal stress protein A CDC59_RS11035 01e4e5ed2c7906f028bd05c35d38243f 151 PRINTS PR01438 Universal stress protein signature 2 20 3.2E-17 T 29-03-2018 IPR006015 Universal stress protein A CDC59_RS11035 01e4e5ed2c7906f028bd05c35d38243f 151 PRINTS PR01438 Universal stress protein signature 124 146 3.2E-17 T 29-03-2018 IPR006015 Universal stress protein A CDC59_RS11035 01e4e5ed2c7906f028bd05c35d38243f 151 Gene3D G3DSA:3.40.50.620 2 150 1.4E-31 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDC59_RS11035 01e4e5ed2c7906f028bd05c35d38243f 151 PIRSF PIRSF006276 1 143 1.0E-17 T 29-03-2018 IPR006015 Universal stress protein A CDC59_RS11035 01e4e5ed2c7906f028bd05c35d38243f 151 SUPERFAMILY SSF52402 1 146 4.19E-33 T 29-03-2018 CDC59_RS18880 611bb97e510319193373d70f9b77beb8 541 Pfam PF00437 Type II/IV secretion system protein 176 446 2.6E-72 T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CDC59_RS18880 611bb97e510319193373d70f9b77beb8 541 SUPERFAMILY SSF160246 21 110 1.6E-7 T 29-03-2018 CDC59_RS18880 611bb97e510319193373d70f9b77beb8 541 Gene3D G3DSA:3.30.450.90 138 275 3.6E-36 T 29-03-2018 CDC59_RS18880 611bb97e510319193373d70f9b77beb8 541 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 375 389 - T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CDC59_RS18880 611bb97e510319193373d70f9b77beb8 541 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 27 111 4.8E-7 T 29-03-2018 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 CDC59_RS18880 611bb97e510319193373d70f9b77beb8 541 SMART SM00382 308 429 0.0022 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS18880 611bb97e510319193373d70f9b77beb8 541 SUPERFAMILY SSF52540 167 536 2.02E-89 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS18880 611bb97e510319193373d70f9b77beb8 541 Gene3D G3DSA:3.40.50.300 281 541 3.9E-52 T 29-03-2018 CDC59_RS13170 848ecd110d16e618bf3497974c97f0e0 294 Pfam PF00756 Putative esterase 35 286 3.2E-53 T 29-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 CDC59_RS13170 848ecd110d16e618bf3497974c97f0e0 294 SUPERFAMILY SSF53474 15 293 3.59E-86 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS13170 848ecd110d16e618bf3497974c97f0e0 294 Gene3D G3DSA:3.40.50.1820 10 294 1.0E-42 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS13170 848ecd110d16e618bf3497974c97f0e0 294 TIGRFAM TIGR02821 fghA_ester_D: S-formylglutathione hydrolase 16 293 1.6E-132 T 29-03-2018 IPR014186 S-formylglutathione hydrolase GO:0018738|GO:0046294 KEGG: 00680+3.1.2.12|MetaCyc: PWY-1801|Reactome: R-HSA-156590 CDC59_RS11170 9db26a61ffd9e92b96aa26255d08c23f 328 Gene3D G3DSA:1.10.3720.10 2 308 5.7E-41 T 29-03-2018 CDC59_RS11170 9db26a61ffd9e92b96aa26255d08c23f 328 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 319 5.0E-40 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS11170 9db26a61ffd9e92b96aa26255d08c23f 328 SUPERFAMILY SSF161098 89 305 3.05E-21 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS02460 b9a2e665fbbaed0da1a5946971c39b69 210 Gene3D G3DSA:1.10.1660.10 20 116 7.3E-4 T 29-03-2018 CDC59_RS02460 b9a2e665fbbaed0da1a5946971c39b69 210 Pfam PF05137 Fimbrial assembly protein (PilN) 108 189 1.5E-20 T 29-03-2018 IPR007813 Fimbrial assembly PilN CDC59_RS14075 62343c838f3d8553ce36327978730b8c 257 SUPERFAMILY SSF53448 12 248 2.04E-27 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDC59_RS14075 62343c838f3d8553ce36327978730b8c 257 Gene3D G3DSA:3.90.550.10 3 247 2.5E-23 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDC59_RS14075 62343c838f3d8553ce36327978730b8c 257 Pfam PF00535 Glycosyl transferase family 2 12 132 7.3E-19 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CDC59_RS11110 1415229e506841703dcb8bfab8dba68b 404 Pfam PF00589 Phage integrase family 230 362 2.2E-10 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CDC59_RS11110 1415229e506841703dcb8bfab8dba68b 404 Pfam PF13356 Arm DNA-binding domain 3 86 3.4E-18 T 29-03-2018 IPR025166 Integrase, DNA-binding domain CDC59_RS11110 1415229e506841703dcb8bfab8dba68b 404 Gene3D G3DSA:1.10.150.130 88 206 4.2E-19 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal CDC59_RS11110 1415229e506841703dcb8bfab8dba68b 404 SUPERFAMILY SSF56349 99 382 2.0E-53 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CDC59_RS11110 1415229e506841703dcb8bfab8dba68b 404 Gene3D G3DSA:1.10.443.10 216 381 2.2E-18 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CDC59_RS05010 86e863efd8bd8351930585e86988046f 189 SMART SM00867 20 185 2.3E-44 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CDC59_RS05010 86e863efd8bd8351930585e86988046f 189 SUPERFAMILY SSF101874 21 187 3.14E-41 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CDC59_RS05010 86e863efd8bd8351930585e86988046f 189 Gene3D G3DSA:2.40.128.110 20 186 3.6E-38 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CDC59_RS05010 86e863efd8bd8351930585e86988046f 189 Pfam PF04264 YceI-like domain 24 184 8.6E-33 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CDC59_RS14950 8642a93cde902dda3b3d9e78413a7757 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 3.4E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS14950 8642a93cde902dda3b3d9e78413a7757 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 3.4E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS14950 8642a93cde902dda3b3d9e78413a7757 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 3.4E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS14950 8642a93cde902dda3b3d9e78413a7757 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 3.4E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS14950 8642a93cde902dda3b3d9e78413a7757 236 Gene3D G3DSA:3.40.50.720 1 236 4.0E-40 T 29-03-2018 CDC59_RS14950 8642a93cde902dda3b3d9e78413a7757 236 SUPERFAMILY SSF51735 9 236 5.34E-62 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS14950 8642a93cde902dda3b3d9e78413a7757 236 Pfam PF00106 short chain dehydrogenase 10 196 2.5E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS11520 085d5650365f7e18ce06dd65160c4572 901 Gene3D G3DSA:3.30.499.10 370 577 3.8E-64 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS11520 085d5650365f7e18ce06dd65160c4572 901 ProSitePatterns PS00450 Aconitase family signature 1. 428 444 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CDC59_RS11520 085d5650365f7e18ce06dd65160c4572 901 Gene3D G3DSA:3.30.499.10 37 236 3.1E-69 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS11520 085d5650365f7e18ce06dd65160c4572 901 Gene3D G3DSA:3.20.19.10 654 900 7.5E-89 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CDC59_RS11520 085d5650365f7e18ce06dd65160c4572 901 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 20 899 0.0 T 29-03-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 CDC59_RS11520 085d5650365f7e18ce06dd65160c4572 901 Gene3D G3DSA:3.40.1060.10 237 369 8.6E-43 T 29-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS11520 085d5650365f7e18ce06dd65160c4572 901 PRINTS PR00415 Aconitase family signature 200 213 4.3E-40 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS11520 085d5650365f7e18ce06dd65160c4572 901 PRINTS PR00415 Aconitase family signature 290 303 4.3E-40 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS11520 085d5650365f7e18ce06dd65160c4572 901 PRINTS PR00415 Aconitase family signature 494 507 4.3E-40 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS11520 085d5650365f7e18ce06dd65160c4572 901 PRINTS PR00415 Aconitase family signature 147 160 4.3E-40 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS11520 085d5650365f7e18ce06dd65160c4572 901 PRINTS PR00415 Aconitase family signature 214 229 4.3E-40 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS11520 085d5650365f7e18ce06dd65160c4572 901 PRINTS PR00415 Aconitase family signature 432 443 4.3E-40 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS11520 085d5650365f7e18ce06dd65160c4572 901 PRINTS PR00415 Aconitase family signature 370 384 4.3E-40 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS11520 085d5650365f7e18ce06dd65160c4572 901 PRINTS PR00415 Aconitase family signature 171 179 4.3E-40 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS11520 085d5650365f7e18ce06dd65160c4572 901 PRINTS PR00415 Aconitase family signature 276 289 4.3E-40 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS11520 085d5650365f7e18ce06dd65160c4572 901 ProSitePatterns PS01244 Aconitase family signature 2. 494 507 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CDC59_RS11520 085d5650365f7e18ce06dd65160c4572 901 Pfam PF00330 Aconitase family (aconitate hydratase) 70 563 3.1E-177 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS11520 085d5650365f7e18ce06dd65160c4572 901 SUPERFAMILY SSF53732 18 626 2.62E-214 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS11520 085d5650365f7e18ce06dd65160c4572 901 SUPERFAMILY SSF52016 636 899 1.92E-80 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CDC59_RS11520 085d5650365f7e18ce06dd65160c4572 901 Pfam PF00694 Aconitase C-terminal domain 693 825 1.6E-40 T 29-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS06785 e809825708e6bf0cbd7554656271cd79 167 PIRSF PIRSF000194 1 164 1.0E-64 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CDC59_RS06785 e809825708e6bf0cbd7554656271cd79 167 SUPERFAMILY SSF53597 4 161 1.7E-59 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CDC59_RS06785 e809825708e6bf0cbd7554656271cd79 167 Gene3D G3DSA:3.40.430.10 1 163 3.0E-55 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CDC59_RS06785 e809825708e6bf0cbd7554656271cd79 167 Pfam PF00186 Dihydrofolate reductase 4 161 3.6E-60 T 29-03-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0006545|GO:0009165|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CDC59_RS06785 e809825708e6bf0cbd7554656271cd79 167 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 15 37 - T 29-03-2018 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-539107 CDC59_RS06785 e809825708e6bf0cbd7554656271cd79 167 PRINTS PR00070 Dihydrofolate reductase signature 42 53 6.8E-16 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CDC59_RS06785 e809825708e6bf0cbd7554656271cd79 167 PRINTS PR00070 Dihydrofolate reductase signature 29 37 6.8E-16 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CDC59_RS06785 e809825708e6bf0cbd7554656271cd79 167 PRINTS PR00070 Dihydrofolate reductase signature 93 107 6.8E-16 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CDC59_RS06785 e809825708e6bf0cbd7554656271cd79 167 PRINTS PR00070 Dihydrofolate reductase signature 15 25 6.8E-16 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CDC59_RS17930 12940a1e28e70e7f56e67f95a3d4027b 406 PIRSF PIRSF037238 25 403 3.0E-115 T 29-03-2018 IPR017150 Peptidase M20, glutamate carboxypeptidase CDC59_RS17930 12940a1e28e70e7f56e67f95a3d4027b 406 Gene3D G3DSA:3.40.630.10 23 406 7.6E-62 T 29-03-2018 CDC59_RS17930 12940a1e28e70e7f56e67f95a3d4027b 406 Pfam PF01546 Peptidase family M20/M25/M40 102 400 9.0E-34 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CDC59_RS17930 12940a1e28e70e7f56e67f95a3d4027b 406 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 101 110 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CDC59_RS17930 12940a1e28e70e7f56e67f95a3d4027b 406 Pfam PF07687 Peptidase dimerisation domain 205 302 1.0E-20 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CDC59_RS17930 12940a1e28e70e7f56e67f95a3d4027b 406 SUPERFAMILY SSF53187 26 216 9.57E-59 T 29-03-2018 CDC59_RS17930 12940a1e28e70e7f56e67f95a3d4027b 406 SUPERFAMILY SSF53187 328 403 9.57E-59 T 29-03-2018 CDC59_RS17930 12940a1e28e70e7f56e67f95a3d4027b 406 SUPERFAMILY SSF55031 207 319 3.93E-23 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CDC59_RS05510 fc7efbf4bef6fc2a054a7fe6ad2ed43a 457 Gene3D G3DSA:1.20.5.170 209 232 1.7E-14 T 29-03-2018 CDC59_RS05510 fc7efbf4bef6fc2a054a7fe6ad2ed43a 457 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 431 8.5E-135 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CDC59_RS05510 fc7efbf4bef6fc2a054a7fe6ad2ed43a 457 SUPERFAMILY SSF48179 209 306 1.0E-31 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CDC59_RS05510 fc7efbf4bef6fc2a054a7fe6ad2ed43a 457 Gene3D G3DSA:3.40.50.720 1 207 5.6E-62 T 29-03-2018 CDC59_RS05510 fc7efbf4bef6fc2a054a7fe6ad2ed43a 457 SUPERFAMILY SSF52413 310 445 4.05E-39 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CDC59_RS05510 fc7efbf4bef6fc2a054a7fe6ad2ed43a 457 SUPERFAMILY SSF51735 1 199 1.65E-53 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS05510 fc7efbf4bef6fc2a054a7fe6ad2ed43a 457 PIRSF PIRSF000124 1 450 3.9E-148 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CDC59_RS05510 fc7efbf4bef6fc2a054a7fe6ad2ed43a 457 PIRSF PIRSF500134 1 453 5.5E-188 T 29-03-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 CDC59_RS05510 fc7efbf4bef6fc2a054a7fe6ad2ed43a 457 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 209 301 8.8E-37 T 29-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CDC59_RS05510 fc7efbf4bef6fc2a054a7fe6ad2ed43a 457 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 185 1.2E-64 T 29-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CDC59_RS05510 fc7efbf4bef6fc2a054a7fe6ad2ed43a 457 Gene3D G3DSA:3.40.50.720 233 447 2.5E-73 T 29-03-2018 CDC59_RS05510 fc7efbf4bef6fc2a054a7fe6ad2ed43a 457 SMART SM00984 325 435 2.1E-50 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CDC59_RS05510 fc7efbf4bef6fc2a054a7fe6ad2ed43a 457 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 325 434 7.8E-33 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CDC59_RS03775 d9530648db00776644085609e4d796ba 428 SUPERFAMILY SSF55031 222 338 4.36E-26 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CDC59_RS03775 d9530648db00776644085609e4d796ba 428 Gene3D G3DSA:3.40.630.10 1 267 3.4E-39 T 29-03-2018 CDC59_RS03775 d9530648db00776644085609e4d796ba 428 SUPERFAMILY SSF53187 345 416 1.31E-83 T 29-03-2018 CDC59_RS03775 d9530648db00776644085609e4d796ba 428 SUPERFAMILY SSF53187 6 232 1.31E-83 T 29-03-2018 CDC59_RS03775 d9530648db00776644085609e4d796ba 428 PIRSF PIRSF001235 13 422 2.1E-127 T 29-03-2018 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 CDC59_RS03775 d9530648db00776644085609e4d796ba 428 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 17 415 1.0E-121 T 29-03-2018 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 CDC59_RS03775 d9530648db00776644085609e4d796ba 428 Gene3D G3DSA:3.40.630.10 268 419 2.5E-25 T 29-03-2018 CDC59_RS03775 d9530648db00776644085609e4d796ba 428 Pfam PF01546 Peptidase family M20/M25/M40 89 415 9.7E-36 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CDC59_RS03775 d9530648db00776644085609e4d796ba 428 Pfam PF07687 Peptidase dimerisation domain 221 321 1.5E-8 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CDC59_RS23180 67e244a06067007d875c289d3d7e293d 231 Pfam PF03737 Aldolase/RraA 32 179 8.7E-40 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CDC59_RS23180 67e244a06067007d875c289d3d7e293d 231 Gene3D G3DSA:3.50.30.40 24 199 8.6E-52 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CDC59_RS23180 67e244a06067007d875c289d3d7e293d 231 TIGRFAM TIGR02798 ligK_PcmE: 4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase 9 230 1.4E-112 T 29-03-2018 IPR014165 4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase KEGG: 00362+4.1.3.17|KEGG: 00660+4.1.3.17|MetaCyc: PWY-7701 CDC59_RS23180 67e244a06067007d875c289d3d7e293d 231 SUPERFAMILY SSF89562 28 189 3.53E-47 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CDC59_RS05270 d2dc7e6ea76bfbd4932db113c8b7c256 233 Pfam PF10979 Protein of unknown function (DUF2786) 6 43 3.2E-15 T 29-03-2018 IPR024498 Domain of unknown function DUF2786 CDC59_RS05270 d2dc7e6ea76bfbd4932db113c8b7c256 233 PIRSF PIRSF028111 1 230 6.1E-58 T 29-03-2018 IPR016868 Bacteriophage B3, Orf5 CDC59_RS04115 bee6170d18ed934797e07d4ba6dcc628 630 Pfam PF01063 Amino-transferase class IV 414 623 4.5E-46 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CDC59_RS04115 bee6170d18ed934797e07d4ba6dcc628 630 Gene3D G3DSA:3.60.120.10 2 402 1.2E-114 T 29-03-2018 IPR005801 ADC synthase GO:0009058 CDC59_RS04115 bee6170d18ed934797e07d4ba6dcc628 630 Gene3D G3DSA:3.30.470.10 403 486 5.0E-19 T 29-03-2018 CDC59_RS04115 bee6170d18ed934797e07d4ba6dcc628 630 Gene3D G3DSA:3.20.10.10 491 624 4.9E-32 T 29-03-2018 CDC59_RS04115 bee6170d18ed934797e07d4ba6dcc628 630 SUPERFAMILY SSF56322 121 406 2.88E-96 T 29-03-2018 IPR005801 ADC synthase GO:0009058 CDC59_RS04115 bee6170d18ed934797e07d4ba6dcc628 630 Pfam PF00425 chorismate binding enzyme 135 401 1.0E-80 T 29-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal CDC59_RS04115 bee6170d18ed934797e07d4ba6dcc628 630 SUPERFAMILY SSF56752 353 623 1.96E-58 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CDC59_RS04115 bee6170d18ed934797e07d4ba6dcc628 630 PRINTS PR00095 Anthranilate synthase component I signature 251 264 2.4E-10 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CDC59_RS04115 bee6170d18ed934797e07d4ba6dcc628 630 PRINTS PR00095 Anthranilate synthase component I signature 331 345 2.4E-10 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CDC59_RS04115 bee6170d18ed934797e07d4ba6dcc628 630 PRINTS PR00095 Anthranilate synthase component I signature 237 250 2.4E-10 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CDC59_RS02950 99179efee134bfbb3d6eea29a9a82a84 436 Gene3D G3DSA:3.40.50.980 99 262 7.0E-22 T 29-03-2018 CDC59_RS02950 99179efee134bfbb3d6eea29a9a82a84 436 Gene3D G3DSA:3.30.300.30 329 434 5.9E-8 T 29-03-2018 CDC59_RS02950 99179efee134bfbb3d6eea29a9a82a84 436 PIRSF PIRSF006444 3 434 3.8E-198 T 29-03-2018 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 CDC59_RS02950 99179efee134bfbb3d6eea29a9a82a84 436 TIGRFAM TIGR02155 PA_CoA_ligase: phenylacetate-CoA ligase 14 432 6.4E-206 T 29-03-2018 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 CDC59_RS02950 99179efee134bfbb3d6eea29a9a82a84 436 SUPERFAMILY SSF56801 26 389 1.22E-61 T 29-03-2018 CDC59_RS02950 99179efee134bfbb3d6eea29a9a82a84 436 Pfam PF14535 AMP-binding enzyme C-terminal domain 339 432 2.0E-23 T 29-03-2018 IPR028154 AMP-dependent ligase, C-terminal CDC59_RS02950 99179efee134bfbb3d6eea29a9a82a84 436 Pfam PF00501 AMP-binding enzyme 85 292 1.5E-15 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CDC59_RS02950 99179efee134bfbb3d6eea29a9a82a84 436 Gene3D G3DSA:3.40.50.980 15 98 0.12 T 29-03-2018 CDC59_RS09575 bae485b30bae322e006e545e478cc304 163 Pfam PF00866 Ring hydroxylating beta subunit 15 155 9.4E-46 T 29-03-2018 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0003824|GO:0006725|GO:0055114 CDC59_RS09575 bae485b30bae322e006e545e478cc304 163 SUPERFAMILY SSF54427 1 162 7.72E-55 T 29-03-2018 IPR032710 NTF2-like domain CDC59_RS09575 bae485b30bae322e006e545e478cc304 163 Gene3D G3DSA:3.10.450.50 1 163 7.5E-34 T 29-03-2018 CDC59_RS09575 bae485b30bae322e006e545e478cc304 163 TIGRFAM TIGR03232 benzo_1_2_benB: benzoate 1,2-dioxygenase, small subunit 9 163 1.2E-87 T 29-03-2018 IPR017641 Benzoate 1,2-dioxygenase, small subunit GO:0016708|GO:0055114 CDC59_RS13300 9779c0e686fbb922cb69a221c4c40f59 176 SUPERFAMILY SSF52540 4 170 2.11E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS13300 9779c0e686fbb922cb69a221c4c40f59 176 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 4 137 3.3E-46 T 29-03-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 CDC59_RS13300 9779c0e686fbb922cb69a221c4c40f59 176 Gene3D G3DSA:3.40.50.300 3 172 1.6E-30 T 29-03-2018 CDC59_RS13300 9779c0e686fbb922cb69a221c4c40f59 176 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 4 167 1.4E-40 T 29-03-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 CDC59_RS23825 2ddc2549eb84cf23fbce3212d77ab31c 138 Pfam PF01047 MarR family 30 87 2.6E-14 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS23825 2ddc2549eb84cf23fbce3212d77ab31c 138 Gene3D G3DSA:1.10.10.10 3 138 3.2E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS23825 2ddc2549eb84cf23fbce3212d77ab31c 138 SMART SM00347 23 123 9.9E-19 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS23825 2ddc2549eb84cf23fbce3212d77ab31c 138 SUPERFAMILY SSF46785 3 134 3.29E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS23825 2ddc2549eb84cf23fbce3212d77ab31c 138 ProSitePatterns PS01117 MarR-type HTH domain signature. 62 96 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CDC59_RS23825 2ddc2549eb84cf23fbce3212d77ab31c 138 PRINTS PR00598 Bacterial regulatory protein MarR family signature 83 99 1.3E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS23825 2ddc2549eb84cf23fbce3212d77ab31c 138 PRINTS PR00598 Bacterial regulatory protein MarR family signature 47 63 1.3E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS23825 2ddc2549eb84cf23fbce3212d77ab31c 138 PRINTS PR00598 Bacterial regulatory protein MarR family signature 64 79 1.3E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS01190 bb674369de517438df8e412141cb7790 103 TIGRFAM TIGR04490 SoxZ_true: thiosulfate oxidation carrier complex protein SoxZ 6 101 4.8E-39 T 29-03-2018 IPR030995 Thiosulfate oxidation carrier complex protein SoxZ CDC59_RS01190 bb674369de517438df8e412141cb7790 103 Pfam PF08770 Sulphur oxidation protein SoxZ 7 100 3.8E-36 T 29-03-2018 IPR014880 Sulphur oxidation protein SoxZ CDC59_RS01190 bb674369de517438df8e412141cb7790 103 Gene3D G3DSA:2.60.40.10 4 102 6.4E-34 T 29-03-2018 IPR013783 Immunoglobulin-like fold CDC59_RS01190 bb674369de517438df8e412141cb7790 103 SUPERFAMILY SSF81296 1 102 1.34E-31 T 29-03-2018 IPR014756 Immunoglobulin E-set CDC59_RS00585 7c09642f59748f7028d8e618eb8404a2 488 Gene3D G3DSA:3.40.50.10540 223 438 4.3E-70 T 29-03-2018 IPR023606 CoA-transferase family III domain CDC59_RS00585 7c09642f59748f7028d8e618eb8404a2 488 Gene3D G3DSA:3.30.1540.10 113 200 1.7E-12 T 29-03-2018 CDC59_RS00585 7c09642f59748f7028d8e618eb8404a2 488 Pfam PF02515 CoA-transferase family III 228 421 5.7E-44 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 CDC59_RS00585 7c09642f59748f7028d8e618eb8404a2 488 Pfam PF02515 CoA-transferase family III 41 205 2.9E-6 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 CDC59_RS00585 7c09642f59748f7028d8e618eb8404a2 488 SUPERFAMILY SSF89796 226 482 1.16E-57 T 29-03-2018 IPR023606 CoA-transferase family III domain CDC59_RS00585 7c09642f59748f7028d8e618eb8404a2 488 SUPERFAMILY SSF89796 21 216 9.81E-30 T 29-03-2018 IPR023606 CoA-transferase family III domain CDC59_RS07440 1263e9ceb08340a364116409c14c3833 566 Pfam PF04773 FecR protein 128 228 2.7E-16 T 29-03-2018 IPR006860 FecR protein CDC59_RS07440 1263e9ceb08340a364116409c14c3833 566 Gene3D G3DSA:3.10.350.10 39 93 2.0E-10 T 29-03-2018 CDC59_RS07440 1263e9ceb08340a364116409c14c3833 566 Gene3D G3DSA:2.60.40.10 349 459 1.6E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold CDC59_RS07440 1263e9ceb08340a364116409c14c3833 566 SMART SM00257 43 90 3.9E-7 T 29-03-2018 IPR018392 LysM domain CDC59_RS07440 1263e9ceb08340a364116409c14c3833 566 Gene3D G3DSA:2.60.40.10 275 345 4.4E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold CDC59_RS07440 1263e9ceb08340a364116409c14c3833 566 SUPERFAMILY SSF54106 43 90 1.28E-6 T 29-03-2018 IPR018392 LysM domain CDC59_RS07440 1263e9ceb08340a364116409c14c3833 566 PIRSF PIRSF029644 4 535 2.1E-198 T 29-03-2018 IPR016930 Uncharacterised conserved protein UCP029644, LysM, PA4035 CDC59_RS07440 1263e9ceb08340a364116409c14c3833 566 Pfam PF01476 LysM domain 44 90 2.6E-9 T 29-03-2018 IPR018392 LysM domain CDC59_RS05185 7f829ec61d6175a6190e75b5bef94c01 166 Gene3D G3DSA:1.10.10.60 4 116 1.6E-5 T 29-03-2018 CDC59_RS05185 7f829ec61d6175a6190e75b5bef94c01 166 Pfam PF08822 Protein of unknown function (DUF1804) 1 161 3.2E-47 T 29-03-2018 IPR014926 Bacteriophage D3112, Orf24 CDC59_RS16985 c8c2831f9724881270212395cad301fe 236 Gene3D G3DSA:3.40.50.2300 1 120 1.3E-11 T 29-03-2018 CDC59_RS16985 c8c2831f9724881270212395cad301fe 236 SMART SM00448 1 115 1.8E-5 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS16985 c8c2831f9724881270212395cad301fe 236 SUPERFAMILY SSF46894 148 211 1.7E-16 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CDC59_RS16985 c8c2831f9724881270212395cad301fe 236 SUPERFAMILY SSF52172 4 127 1.35E-12 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS16985 c8c2831f9724881270212395cad301fe 236 Pfam PF00072 Response regulator receiver domain 4 114 3.7E-8 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS16985 c8c2831f9724881270212395cad301fe 236 SMART SM00421 150 207 3.2E-17 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS16985 c8c2831f9724881270212395cad301fe 236 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 1.8E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS16985 c8c2831f9724881270212395cad301fe 236 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 1.8E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS16985 c8c2831f9724881270212395cad301fe 236 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 1.8E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS16985 c8c2831f9724881270212395cad301fe 236 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 207 1.1E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS16985 c8c2831f9724881270212395cad301fe 236 Gene3D G3DSA:1.10.10.10 121 216 2.0E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS21860 256e9ac638a9125124eab22650f9b993 88 SUPERFAMILY SSF46894 10 79 6.46E-21 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CDC59_RS21860 256e9ac638a9125124eab22650f9b993 88 Pfam PF00196 Bacterial regulatory proteins, luxR family 22 76 1.8E-19 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS21860 256e9ac638a9125124eab22650f9b993 88 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 23 37 3.3E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS21860 256e9ac638a9125124eab22650f9b993 88 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 53 65 3.3E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS21860 256e9ac638a9125124eab22650f9b993 88 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 37 53 3.3E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS21860 256e9ac638a9125124eab22650f9b993 88 Gene3D G3DSA:1.10.10.10 15 86 1.1E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS21860 256e9ac638a9125124eab22650f9b993 88 SMART SM00421 20 77 1.5E-22 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS09665 44d47fc263d384fb84af4646dff364f0 219 SUPERFAMILY SSF56349 7 201 1.35E-17 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CDC59_RS09665 44d47fc263d384fb84af4646dff364f0 219 Pfam PF00589 Phage integrase family 6 202 5.5E-11 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CDC59_RS09665 44d47fc263d384fb84af4646dff364f0 219 Gene3D G3DSA:1.10.443.10 5 216 1.9E-18 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CDC59_RS13680 4d4c2f701f76bc70733283bfc55b004e 692 Pfam PF00563 EAL domain 439 674 4.3E-75 T 29-03-2018 IPR001633 EAL domain CDC59_RS13680 4d4c2f701f76bc70733283bfc55b004e 692 SMART SM00052 433 679 3.0E-127 T 29-03-2018 IPR001633 EAL domain CDC59_RS13680 4d4c2f701f76bc70733283bfc55b004e 692 Gene3D G3DSA:3.30.70.270 264 430 1.3E-61 T 29-03-2018 CDC59_RS13680 4d4c2f701f76bc70733283bfc55b004e 692 SUPERFAMILY SSF141868 439 683 4.58E-91 T 29-03-2018 IPR001633 EAL domain CDC59_RS13680 4d4c2f701f76bc70733283bfc55b004e 692 SMART SM00267 252 423 2.1E-67 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS13680 4d4c2f701f76bc70733283bfc55b004e 692 SUPERFAMILY SSF55073 268 424 1.28E-50 T 29-03-2018 IPR029787 Nucleotide cyclase CDC59_RS13680 4d4c2f701f76bc70733283bfc55b004e 692 Pfam PF00990 Diguanylate cyclase, GGDEF domain 263 418 3.2E-46 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS13680 4d4c2f701f76bc70733283bfc55b004e 692 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 260 421 3.9E-41 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS13680 4d4c2f701f76bc70733283bfc55b004e 692 Gene3D G3DSA:3.20.20.450 431 683 6.4E-105 T 29-03-2018 IPR001633 EAL domain CDC59_RS13680 4d4c2f701f76bc70733283bfc55b004e 692 Pfam PF03707 Bacterial signalling protein N terminal repeat 115 172 7.3E-20 T 29-03-2018 IPR005330 MHYT domain CDC59_RS13680 4d4c2f701f76bc70733283bfc55b004e 692 Pfam PF03707 Bacterial signalling protein N terminal repeat 52 109 7.4E-24 T 29-03-2018 IPR005330 MHYT domain CDC59_RS13680 4d4c2f701f76bc70733283bfc55b004e 692 Pfam PF03707 Bacterial signalling protein N terminal repeat 182 246 4.1E-12 T 29-03-2018 IPR005330 MHYT domain CDC59_RS14405 efda11e44c37068f61f214b22371f597 972 SUPERFAMILY SSF55073 817 970 1.26E-46 T 29-03-2018 IPR029787 Nucleotide cyclase CDC59_RS14405 efda11e44c37068f61f214b22371f597 972 Gene3D G3DSA:3.30.70.270 807 972 6.1E-61 T 29-03-2018 CDC59_RS14405 efda11e44c37068f61f214b22371f597 972 Gene3D G3DSA:3.30.450.20 679 806 1.4E-20 T 29-03-2018 CDC59_RS14405 efda11e44c37068f61f214b22371f597 972 Gene3D G3DSA:3.30.450.20 538 678 7.3E-25 T 29-03-2018 CDC59_RS14405 efda11e44c37068f61f214b22371f597 972 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 808 970 4.0E-45 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS14405 efda11e44c37068f61f214b22371f597 972 SMART SM00267 801 972 7.5E-55 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS14405 efda11e44c37068f61f214b22371f597 972 SUPERFAMILY SSF55785 666 799 1.16E-16 T 29-03-2018 IPR000014 PAS domain CDC59_RS14405 efda11e44c37068f61f214b22371f597 972 Pfam PF08448 PAS fold 686 803 1.0E-9 T 29-03-2018 IPR013656 PAS fold-4 CDC59_RS14405 efda11e44c37068f61f214b22371f597 972 Pfam PF08448 PAS fold 563 669 1.2E-11 T 29-03-2018 IPR013656 PAS fold-4 CDC59_RS14405 efda11e44c37068f61f214b22371f597 972 Pfam PF00990 Diguanylate cyclase, GGDEF domain 812 969 2.5E-46 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS14405 efda11e44c37068f61f214b22371f597 972 SMART SM00091 556 622 0.006 T 29-03-2018 IPR000014 PAS domain CDC59_RS14405 efda11e44c37068f61f214b22371f597 972 SMART SM00091 680 746 0.025 T 29-03-2018 IPR000014 PAS domain CDC59_RS14405 efda11e44c37068f61f214b22371f597 972 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 677 808 2.3E-8 T 29-03-2018 IPR000014 PAS domain CDC59_RS14405 efda11e44c37068f61f214b22371f597 972 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 553 675 3.3E-11 T 29-03-2018 IPR000014 PAS domain CDC59_RS14405 efda11e44c37068f61f214b22371f597 972 SUPERFAMILY SSF55785 544 666 2.65E-16 T 29-03-2018 IPR000014 PAS domain CDC59_RS06655 716d5b63fe200dcaf05bf4b98efb985f 349 Gene3D G3DSA:3.40.50.300 1 257 1.5E-76 T 29-03-2018 CDC59_RS06655 716d5b63fe200dcaf05bf4b98efb985f 349 SUPERFAMILY SSF52540 1 241 4.46E-81 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS06655 716d5b63fe200dcaf05bf4b98efb985f 349 Pfam PF09383 NIL domain 273 344 6.6E-23 T 29-03-2018 IPR018449 NIL domain CDC59_RS06655 716d5b63fe200dcaf05bf4b98efb985f 349 SMART SM00930 270 345 3.3E-29 T 29-03-2018 IPR018449 NIL domain CDC59_RS06655 716d5b63fe200dcaf05bf4b98efb985f 349 SMART SM00382 31 228 1.3E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS06655 716d5b63fe200dcaf05bf4b98efb985f 349 SUPERFAMILY SSF55021 257 348 1.6E-23 T 29-03-2018 CDC59_RS06655 716d5b63fe200dcaf05bf4b98efb985f 349 Gene3D G3DSA:3.30.70.260 258 349 1.5E-28 T 29-03-2018 CDC59_RS06655 716d5b63fe200dcaf05bf4b98efb985f 349 Pfam PF00005 ABC transporter 22 170 3.3E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS06655 716d5b63fe200dcaf05bf4b98efb985f 349 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS07835 f30d656051c78fb2095e0db693aa67b2 241 SUPERFAMILY SSF50800 5 230 1.26E-77 T 29-03-2018 IPR011037 Pyruvate kinase-like, insert domain CDC59_RS07835 f30d656051c78fb2095e0db693aa67b2 241 Gene3D G3DSA:2.40.33.20 6 238 3.7E-60 T 29-03-2018 CDC59_RS07835 f30d656051c78fb2095e0db693aa67b2 241 Pfam PF03473 MOSC domain 52 166 1.0E-29 T 29-03-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 CDC59_RS07835 f30d656051c78fb2095e0db693aa67b2 241 Pfam PF03475 3-alpha domain 176 218 1.1E-13 T 29-03-2018 IPR005163 3-alpha domain CDC59_RS21020 07bc2d9595dfa6dc5b9c0602b0e5d744 221 TIGRFAM TIGR01493 HAD-SF-IA-v2: HAD hydrolase, family IA, variant 2 7 182 1.3E-14 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDC59_RS21020 07bc2d9595dfa6dc5b9c0602b0e5d744 221 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 153 173 3.5E-6 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDC59_RS21020 07bc2d9595dfa6dc5b9c0602b0e5d744 221 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 135 151 3.5E-6 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDC59_RS21020 07bc2d9595dfa6dc5b9c0602b0e5d744 221 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 5 16 3.5E-6 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDC59_RS21020 07bc2d9595dfa6dc5b9c0602b0e5d744 221 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 104 182 3.1E-6 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDC59_RS21020 07bc2d9595dfa6dc5b9c0602b0e5d744 221 Pfam PF13419 Haloacid dehalogenase-like hydrolase 92 187 1.7E-8 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS21020 07bc2d9595dfa6dc5b9c0602b0e5d744 221 TIGRFAM TIGR01428 HAD_type_II: haloacid dehalogenase, type II 6 199 1.4E-49 T 29-03-2018 IPR006328 L-2-Haloacid dehalogenase GO:0008152|GO:0019120 KEGG: 00361+3.8.1.2|KEGG: 00625+3.8.1.2|MetaCyc: PWY-7425 CDC59_RS21020 07bc2d9595dfa6dc5b9c0602b0e5d744 221 Gene3D G3DSA:3.40.50.1000 2 198 1.0E-16 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS21020 07bc2d9595dfa6dc5b9c0602b0e5d744 221 SUPERFAMILY SSF56784 5 219 3.96E-37 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS17510 843dd8a9b26d3b2b76a41829fd91e6bd 902 Gene3D G3DSA:3.20.19.10 640 876 2.5E-63 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CDC59_RS17510 843dd8a9b26d3b2b76a41829fd91e6bd 902 Gene3D G3DSA:3.40.1060.10 236 367 2.6E-37 T 29-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS17510 843dd8a9b26d3b2b76a41829fd91e6bd 902 Pfam PF00694 Aconitase C-terminal domain 675 802 1.3E-35 T 29-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS17510 843dd8a9b26d3b2b76a41829fd91e6bd 902 Gene3D G3DSA:3.30.499.10 368 563 4.7E-47 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS17510 843dd8a9b26d3b2b76a41829fd91e6bd 902 SUPERFAMILY SSF53732 12 598 4.84E-179 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS17510 843dd8a9b26d3b2b76a41829fd91e6bd 902 SUPERFAMILY SSF52016 617 873 1.82E-63 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CDC59_RS17510 843dd8a9b26d3b2b76a41829fd91e6bd 902 PRINTS PR00415 Aconitase family signature 166 174 1.5E-36 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS17510 843dd8a9b26d3b2b76a41829fd91e6bd 902 PRINTS PR00415 Aconitase family signature 275 288 1.5E-36 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS17510 843dd8a9b26d3b2b76a41829fd91e6bd 902 PRINTS PR00415 Aconitase family signature 199 212 1.5E-36 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS17510 843dd8a9b26d3b2b76a41829fd91e6bd 902 PRINTS PR00415 Aconitase family signature 289 302 1.5E-36 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS17510 843dd8a9b26d3b2b76a41829fd91e6bd 902 PRINTS PR00415 Aconitase family signature 213 228 1.5E-36 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS17510 843dd8a9b26d3b2b76a41829fd91e6bd 902 PRINTS PR00415 Aconitase family signature 142 155 1.5E-36 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS17510 843dd8a9b26d3b2b76a41829fd91e6bd 902 PRINTS PR00415 Aconitase family signature 418 429 1.5E-36 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS17510 843dd8a9b26d3b2b76a41829fd91e6bd 902 PRINTS PR00415 Aconitase family signature 368 382 1.5E-36 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS17510 843dd8a9b26d3b2b76a41829fd91e6bd 902 PRINTS PR00415 Aconitase family signature 480 493 1.5E-36 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS17510 843dd8a9b26d3b2b76a41829fd91e6bd 902 ProSitePatterns PS01244 Aconitase family signature 2. 480 493 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CDC59_RS17510 843dd8a9b26d3b2b76a41829fd91e6bd 902 Pfam PF00330 Aconitase family (aconitate hydratase) 71 549 9.7E-153 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS17510 843dd8a9b26d3b2b76a41829fd91e6bd 902 Gene3D G3DSA:3.30.499.10 43 235 4.3E-59 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS17510 843dd8a9b26d3b2b76a41829fd91e6bd 902 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 25 871 8.4E-294 T 29-03-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 CDC59_RS06045 256178e1c04dbcd787b2d64c40d7acf2 290 Gene3D G3DSA:3.90.550.10 1 280 1.1E-57 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDC59_RS06045 256178e1c04dbcd787b2d64c40d7acf2 290 SUPERFAMILY SSF53448 2 271 9.81E-64 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDC59_RS06045 256178e1c04dbcd787b2d64c40d7acf2 290 Pfam PF00483 Nucleotidyl transferase 11 268 4.1E-27 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CDC59_RS06045 256178e1c04dbcd787b2d64c40d7acf2 290 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 4 267 1.3E-115 T 29-03-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 CDC59_RS11850 490523c74d0a3a8b5acd858cdec385c7 418 Gene3D G3DSA:3.40.50.2300 11 163 6.4E-15 T 29-03-2018 CDC59_RS11850 490523c74d0a3a8b5acd858cdec385c7 418 Gene3D G3DSA:3.40.50.2300 164 341 7.6E-27 T 29-03-2018 CDC59_RS11850 490523c74d0a3a8b5acd858cdec385c7 418 SUPERFAMILY SSF53822 26 378 1.48E-62 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CDC59_RS11850 490523c74d0a3a8b5acd858cdec385c7 418 Pfam PF13458 Periplasmic binding protein 26 380 1.2E-63 T 29-03-2018 IPR028081 Leucine-binding protein domain CDC59_RS10170 e003faf106c2c0cbcf409ff459502eb6 806 Gene3D G3DSA:1.10.4060.10 125 214 1.2E-33 T 29-03-2018 CDC59_RS10170 e003faf106c2c0cbcf409ff459502eb6 806 SMART SM00464 13 205 2.2E-76 T 29-03-2018 IPR003111 Lon, substrate-binding domain CDC59_RS10170 e003faf106c2c0cbcf409ff459502eb6 806 Gene3D G3DSA:3.40.50.300 289 506 1.9E-29 T 29-03-2018 CDC59_RS10170 e003faf106c2c0cbcf409ff459502eb6 806 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 679 687 - T 29-03-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 CDC59_RS10170 e003faf106c2c0cbcf409ff459502eb6 806 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 572 775 1.6E-98 T 29-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 CDC59_RS10170 e003faf106c2c0cbcf409ff459502eb6 806 Gene3D G3DSA:1.10.8.60 507 579 3.6E-33 T 29-03-2018 CDC59_RS10170 e003faf106c2c0cbcf409ff459502eb6 806 SUPERFAMILY SSF54211 598 773 6.07E-60 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CDC59_RS10170 e003faf106c2c0cbcf409ff459502eb6 806 TIGRFAM TIGR00763 lon: endopeptidase La 15 774 1.5E-303 T 29-03-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 CDC59_RS10170 e003faf106c2c0cbcf409ff459502eb6 806 Gene3D G3DSA:2.30.130.40 4 121 1.2E-31 T 29-03-2018 CDC59_RS10170 e003faf106c2c0cbcf409ff459502eb6 806 PIRSF PIRSF001174 4 778 0.0 T 29-03-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 CDC59_RS10170 e003faf106c2c0cbcf409ff459502eb6 806 SUPERFAMILY SSF88697 13 204 5.96E-53 T 29-03-2018 IPR015947 PUA-like domain CDC59_RS10170 e003faf106c2c0cbcf409ff459502eb6 806 Hamap MF_01973 Lon protease [lon]. 14 775 71.516 T 29-03-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 CDC59_RS10170 e003faf106c2c0cbcf409ff459502eb6 806 Gene3D G3DSA:3.30.230.10 580 796 8.1E-69 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CDC59_RS10170 e003faf106c2c0cbcf409ff459502eb6 806 SMART SM00382 350 494 4.8E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS10170 e003faf106c2c0cbcf409ff459502eb6 806 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 14 203 1.0E-44 T 29-03-2018 IPR003111 Lon, substrate-binding domain CDC59_RS10170 e003faf106c2c0cbcf409ff459502eb6 806 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 706 725 5.5E-56 T 29-03-2018 CDC59_RS10170 e003faf106c2c0cbcf409ff459502eb6 806 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 676 695 5.5E-56 T 29-03-2018 CDC59_RS10170 e003faf106c2c0cbcf409ff459502eb6 806 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 358 377 5.5E-56 T 29-03-2018 CDC59_RS10170 e003faf106c2c0cbcf409ff459502eb6 806 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 598 614 5.5E-56 T 29-03-2018 CDC59_RS10170 e003faf106c2c0cbcf409ff459502eb6 806 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 729 747 5.5E-56 T 29-03-2018 CDC59_RS10170 e003faf106c2c0cbcf409ff459502eb6 806 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 354 491 2.6E-17 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CDC59_RS10170 e003faf106c2c0cbcf409ff459502eb6 806 SUPERFAMILY SSF52540 315 590 2.68E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS12325 c9b9e59a66f3dbe8e94c7e5df06d4534 347 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 201 214 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CDC59_RS12325 c9b9e59a66f3dbe8e94c7e5df06d4534 347 Pfam PF00155 Aminotransferase class I and II 60 292 7.2E-26 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CDC59_RS12325 c9b9e59a66f3dbe8e94c7e5df06d4534 347 Gene3D G3DSA:3.40.640.10 53 233 6.7E-23 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDC59_RS12325 c9b9e59a66f3dbe8e94c7e5df06d4534 347 TIGRFAM TIGR01140 L_thr_O3P_dcar: threonine-phosphate decarboxylase 11 339 5.8E-107 T 29-03-2018 IPR005860 L-threonine-O-3-phosphate decarboxylase GO:0003824|GO:0009236 KEGG: 00860+4.1.1.81|MetaCyc: PWY-5443 CDC59_RS12325 c9b9e59a66f3dbe8e94c7e5df06d4534 347 Gene3D G3DSA:3.90.1150.10 234 342 1.1E-12 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS12325 c9b9e59a66f3dbe8e94c7e5df06d4534 347 SUPERFAMILY SSF53383 9 339 3.71E-55 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS13395 2fab806ad44dfdb4eca43857d4f9413d 195 Pfam PF11161 Protein of unknown function (DUF2946) 1 192 4.4E-71 T 29-03-2018 IPR021332 Protein of unknown function DUF2944 CDC59_RS20770 42eabdf2dac4e7d70320c46f9e994d3d 666 Gene3D G3DSA:3.40.50.720 135 256 5.3E-24 T 29-03-2018 CDC59_RS20770 42eabdf2dac4e7d70320c46f9e994d3d 666 SUPERFAMILY SSF53335 116 336 1.83E-21 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS20770 42eabdf2dac4e7d70320c46f9e994d3d 666 Gene3D G3DSA:3.40.50.720 286 617 2.9E-59 T 29-03-2018 CDC59_RS20770 42eabdf2dac4e7d70320c46f9e994d3d 666 Pfam PF02719 Polysaccharide biosynthesis protein 289 578 4.0E-121 T 29-03-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain CDC59_RS20770 42eabdf2dac4e7d70320c46f9e994d3d 666 SUPERFAMILY SSF51735 287 558 2.51E-54 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS20770 42eabdf2dac4e7d70320c46f9e994d3d 666 Pfam PF13727 CoA-binding domain 70 244 1.3E-14 T 29-03-2018 CDC59_RS17630 136db3c59a55f75b1b412f968976df5b 822 Gene3D G3DSA:3.40.190.10 9 772 2.2E-5 T 29-03-2018 CDC59_RS17630 136db3c59a55f75b1b412f968976df5b 822 Gene3D G3DSA:2.60.40.1180 773 817 4.9E-5 T 29-03-2018 CDC59_RS11750 e2344930988ab6188c41ef002bd80aa7 488 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 3 482 2.3E-187 T 29-03-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS11750 e2344930988ab6188c41ef002bd80aa7 488 Pfam PF00361 Proton-conducting membrane transporter 130 413 2.2E-79 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS11750 e2344930988ab6188c41ef002bd80aa7 488 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 164 188 3.5E-48 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS11750 e2344930988ab6188c41ef002bd80aa7 488 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 134 153 3.5E-48 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS11750 e2344930988ab6188c41ef002bd80aa7 488 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 321 340 3.5E-48 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS11750 e2344930988ab6188c41ef002bd80aa7 488 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 233 257 3.5E-48 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS11750 e2344930988ab6188c41ef002bd80aa7 488 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 373 399 3.5E-48 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS08320 53b6635bf30498080a3607ce1d0c4c0e 305 SUPERFAMILY SSF53822 21 301 5.45E-83 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CDC59_RS08320 53b6635bf30498080a3607ce1d0c4c0e 305 Pfam PF13407 Periplasmic binding protein domain 23 280 2.5E-62 T 29-03-2018 IPR025997 Periplasmic binding protein CDC59_RS08320 53b6635bf30498080a3607ce1d0c4c0e 305 Gene3D G3DSA:3.40.50.2300 21 129 4.1E-19 T 29-03-2018 CDC59_RS08320 53b6635bf30498080a3607ce1d0c4c0e 305 Gene3D G3DSA:3.40.50.2300 130 305 5.6E-49 T 29-03-2018 CDC59_RS04100 a9f1f0846ddbe92794002ca0594b42bd 134 Gene3D G3DSA:3.10.50.30 45 134 4.8E-23 T 29-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CDC59_RS04100 a9f1f0846ddbe92794002ca0594b42bd 134 PIRSF PIRSF006092 29 126 7.0E-22 T 29-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 CDC59_RS04100 a9f1f0846ddbe92794002ca0594b42bd 134 PIRSF PIRSF006092 1 28 170.0 T 29-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 CDC59_RS04100 a9f1f0846ddbe92794002ca0594b42bd 134 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 49 122 2.4E-19 T 29-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CDC59_RS04100 a9f1f0846ddbe92794002ca0594b42bd 134 SUPERFAMILY SSF54534 48 123 4.05E-17 T 29-03-2018 CDC59_RS04100 a9f1f0846ddbe92794002ca0594b42bd 134 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 87 103 - T 29-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 CDC59_RS06275 2e95826308c0cc8d6c4d358cbd886a1d 302 Hamap MF_00333 Oxygen-dependent coproporphyrinogen-III oxidase [hemF]. 1 277 55.602 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CDC59_RS06275 2e95826308c0cc8d6c4d358cbd886a1d 302 Pfam PF01218 Coproporphyrinogen III oxidase 6 302 2.3E-124 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CDC59_RS06275 2e95826308c0cc8d6c4d358cbd886a1d 302 Gene3D G3DSA:3.40.1500.10 1 302 2.4E-132 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CDC59_RS06275 2e95826308c0cc8d6c4d358cbd886a1d 302 PIRSF PIRSF000166 1 302 3.2E-119 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CDC59_RS06275 2e95826308c0cc8d6c4d358cbd886a1d 302 PRINTS PR00073 Coprogen oxidase signature 27 43 2.5E-67 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CDC59_RS06275 2e95826308c0cc8d6c4d358cbd886a1d 302 PRINTS PR00073 Coprogen oxidase signature 90 114 2.5E-67 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CDC59_RS06275 2e95826308c0cc8d6c4d358cbd886a1d 302 PRINTS PR00073 Coprogen oxidase signature 234 261 2.5E-67 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CDC59_RS06275 2e95826308c0cc8d6c4d358cbd886a1d 302 PRINTS PR00073 Coprogen oxidase signature 162 191 2.5E-67 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CDC59_RS06275 2e95826308c0cc8d6c4d358cbd886a1d 302 PRINTS PR00073 Coprogen oxidase signature 125 147 2.5E-67 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CDC59_RS06275 2e95826308c0cc8d6c4d358cbd886a1d 302 PRINTS PR00073 Coprogen oxidase signature 262 288 2.5E-67 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CDC59_RS06275 2e95826308c0cc8d6c4d358cbd886a1d 302 ProSitePatterns PS01021 Coproporphyrinogen III oxidase signature. 166 190 - T 29-03-2018 IPR018375 Coproporphyrinogen III oxidase, conserved site GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CDC59_RS06275 2e95826308c0cc8d6c4d358cbd886a1d 302 SUPERFAMILY SSF102886 4 302 8.24E-131 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CDC59_RS16800 cf55c47460d4f6e2f54818f8c8fe3b83 155 Gene3D G3DSA:3.40.630.30 1 155 6.8E-29 T 29-03-2018 CDC59_RS16800 cf55c47460d4f6e2f54818f8c8fe3b83 155 Pfam PF13673 Acetyltransferase (GNAT) domain 29 138 1.5E-16 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CDC59_RS16800 cf55c47460d4f6e2f54818f8c8fe3b83 155 SUPERFAMILY SSF55729 1 154 2.23E-34 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDC59_RS22895 ddcd5efc3c500a08830d350e23213254 509 Pfam PF06628 Catalase-related immune-responsive 432 493 6.2E-18 T 29-03-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CDC59_RS22895 ddcd5efc3c500a08830d350e23213254 509 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 352 360 - T 29-03-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CDC59_RS22895 ddcd5efc3c500a08830d350e23213254 509 ProSitePatterns PS00438 Catalase proximal active site signature. 65 81 - T 29-03-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CDC59_RS22895 ddcd5efc3c500a08830d350e23213254 509 Gene3D G3DSA:2.40.180.10 17 376 2.7E-154 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CDC59_RS22895 ddcd5efc3c500a08830d350e23213254 509 SUPERFAMILY SSF56634 19 498 7.38E-198 T 29-03-2018 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CDC59_RS22895 ddcd5efc3c500a08830d350e23213254 509 PRINTS PR00067 Catalase signature 307 334 8.7E-68 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CDC59_RS22895 ddcd5efc3c500a08830d350e23213254 509 PRINTS PR00067 Catalase signature 144 162 8.7E-68 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CDC59_RS22895 ddcd5efc3c500a08830d350e23213254 509 PRINTS PR00067 Catalase signature 339 365 8.7E-68 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CDC59_RS22895 ddcd5efc3c500a08830d350e23213254 509 PRINTS PR00067 Catalase signature 104 122 8.7E-68 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CDC59_RS22895 ddcd5efc3c500a08830d350e23213254 509 PRINTS PR00067 Catalase signature 125 142 8.7E-68 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CDC59_RS22895 ddcd5efc3c500a08830d350e23213254 509 PRINTS PR00067 Catalase signature 42 65 8.7E-68 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CDC59_RS22895 ddcd5efc3c500a08830d350e23213254 509 Pfam PF00199 Catalase 29 404 1.7E-170 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CDC59_RS22895 ddcd5efc3c500a08830d350e23213254 509 SMART SM01060 29 409 1.6E-252 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CDC59_RS22895 ddcd5efc3c500a08830d350e23213254 509 PIRSF PIRSF038928 19 499 1.2E-187 T 29-03-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CDC59_RS18505 3c7a0b7b1078b697a5fd8226271d1a20 371 Gene3D G3DSA:3.40.50.1820 33 361 2.5E-24 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS18505 3c7a0b7b1078b697a5fd8226271d1a20 371 Pfam PF00561 alpha/beta hydrolase fold 77 227 4.8E-16 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS18505 3c7a0b7b1078b697a5fd8226271d1a20 371 PIRSF PIRSF000443 21 370 2.3E-52 T 29-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 CDC59_RS18505 3c7a0b7b1078b697a5fd8226271d1a20 371 SUPERFAMILY SSF53474 41 336 1.35E-58 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS09080 9390cab9d055637b2b3901fe0396f8c0 118 Gene3D G3DSA:3.40.30.10 5 118 4.0E-35 T 29-03-2018 CDC59_RS09080 9390cab9d055637b2b3901fe0396f8c0 118 Pfam PF03960 ArsC family 10 115 1.8E-17 T 29-03-2018 IPR006660 Arsenate reductase-like CDC59_RS09080 9390cab9d055637b2b3901fe0396f8c0 118 SUPERFAMILY SSF52833 7 117 3.79E-33 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS09080 9390cab9d055637b2b3901fe0396f8c0 118 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 8 116 1.3E-29 T 29-03-2018 IPR006504 Transcriptional regulator Spx/MgsR CDC59_RS12880 5f2915f3fc988d6acf44c8a66d4f2a40 442 Pfam PF07690 Major Facilitator Superfamily 38 399 5.2E-29 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDC59_RS12880 5f2915f3fc988d6acf44c8a66d4f2a40 442 ProSitePatterns PS00217 Sugar transport proteins signature 2. 136 161 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CDC59_RS12880 5f2915f3fc988d6acf44c8a66d4f2a40 442 Gene3D G3DSA:1.20.1250.20 2 238 3.6E-24 T 29-03-2018 CDC59_RS12880 5f2915f3fc988d6acf44c8a66d4f2a40 442 SUPERFAMILY SSF103473 23 436 1.31E-68 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS12880 5f2915f3fc988d6acf44c8a66d4f2a40 442 Gene3D G3DSA:1.20.1250.20 239 440 3.3E-23 T 29-03-2018 CDC59_RS12880 5f2915f3fc988d6acf44c8a66d4f2a40 442 ProSitePatterns PS00216 Sugar transport proteins signature 1. 86 102 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CDC59_RS12880 5f2915f3fc988d6acf44c8a66d4f2a40 442 ProSitePatterns PS00216 Sugar transport proteins signature 1. 308 325 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CDC59_RS20430 d39f0dfdc9bd1c3907e989e66ff8ff89 402 Pfam PF00155 Aminotransferase class I and II 34 394 8.7E-69 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CDC59_RS20430 d39f0dfdc9bd1c3907e989e66ff8ff89 402 Gene3D G3DSA:3.40.640.10 47 275 5.7E-48 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDC59_RS20430 d39f0dfdc9bd1c3907e989e66ff8ff89 402 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 238 251 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CDC59_RS20430 d39f0dfdc9bd1c3907e989e66ff8ff89 402 SUPERFAMILY SSF53383 3 399 8.53E-109 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS20430 d39f0dfdc9bd1c3907e989e66ff8ff89 402 Gene3D G3DSA:3.90.1150.10 276 402 1.0E-30 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS15315 e1f37356af6ac719d0a28190b9f7c1af 312 Pfam PF01370 NAD dependent epimerase/dehydratase family 7 204 3.0E-16 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CDC59_RS15315 e1f37356af6ac719d0a28190b9f7c1af 312 SUPERFAMILY SSF51735 1 274 9.4E-47 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS15315 e1f37356af6ac719d0a28190b9f7c1af 312 Gene3D G3DSA:3.40.50.720 2 299 1.0E-33 T 29-03-2018 CDC59_RS09700 ca6c00b8c87c875b589bade2c5ce46f9 509 Pfam PF00324 Amino acid permease 24 479 2.3E-125 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CDC59_RS09700 ca6c00b8c87c875b589bade2c5ce46f9 509 PIRSF PIRSF006060 4 495 1.4E-81 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CDC59_RS09700 ca6c00b8c87c875b589bade2c5ce46f9 509 ProSitePatterns PS00218 Amino acid permeases signature. 49 80 - T 29-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CDC59_RS21135 cabc7fd9f6d843c76dc863ccb46f8831 256 Pfam PF09836 Putative DNA-binding domain 7 85 8.0E-19 T 29-03-2018 IPR018640 Putative DNA-binding domain, bacteria CDC59_RS17650 abb9f75f770c2634ebcbbdd3c92f13a3 239 Gene3D G3DSA:1.10.3720.10 1 223 7.3E-31 T 29-03-2018 CDC59_RS17650 abb9f75f770c2634ebcbbdd3c92f13a3 239 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 2 82 9.1E-15 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CDC59_RS17650 abb9f75f770c2634ebcbbdd3c92f13a3 239 SUPERFAMILY SSF161098 2 211 7.72E-32 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS17650 abb9f75f770c2634ebcbbdd3c92f13a3 239 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 20 221 5.1E-11 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS09670 87a72b6a185a6b9d71b959ed99fc8674 1041 Gene3D G3DSA:3.40.50.300 371 400 0.35 T 29-03-2018 CDC59_RS09670 87a72b6a185a6b9d71b959ed99fc8674 1041 SUPERFAMILY SSF52540 911 995 8.46E-20 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS09670 87a72b6a185a6b9d71b959ed99fc8674 1041 SUPERFAMILY SSF52540 364 563 8.46E-20 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS09670 87a72b6a185a6b9d71b959ed99fc8674 1041 SUPERFAMILY SSF52540 686 708 8.46E-20 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS09670 87a72b6a185a6b9d71b959ed99fc8674 1041 Gene3D G3DSA:1.20.1170.10 455 723 1.0E-6 T 29-03-2018 CDC59_RS09670 87a72b6a185a6b9d71b959ed99fc8674 1041 Gene3D G3DSA:3.20.20.140 16 113 3.8E-5 T 29-03-2018 CDC59_RS09670 87a72b6a185a6b9d71b959ed99fc8674 1041 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 916 983 8.9E-7 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CDC59_RS09670 87a72b6a185a6b9d71b959ed99fc8674 1041 Gene3D G3DSA:3.40.50.300 739 1038 1.0E-13 T 29-03-2018 CDC59_RS13015 0ee40b798358c3886be6ac6719478154 342 Pfam PF01565 FAD binding domain 24 149 4.0E-20 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CDC59_RS13015 0ee40b798358c3886be6ac6719478154 342 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 12 338 1.1E-64 T 29-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDC59_RS13015 0ee40b798358c3886be6ac6719478154 342 Gene3D G3DSA:3.30.43.10 2 72 1.0E-20 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CDC59_RS13015 0ee40b798358c3886be6ac6719478154 342 Gene3D G3DSA:3.90.78.10 234 342 8.9E-36 T 29-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDC59_RS13015 0ee40b798358c3886be6ac6719478154 342 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 342 83.167 T 29-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDC59_RS13015 0ee40b798358c3886be6ac6719478154 342 SUPERFAMILY SSF56194 215 342 2.35E-44 T 29-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDC59_RS13015 0ee40b798358c3886be6ac6719478154 342 Gene3D G3DSA:3.30.465.10 74 231 2.2E-51 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CDC59_RS13015 0ee40b798358c3886be6ac6719478154 342 SUPERFAMILY SSF56176 8 199 6.07E-43 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CDC59_RS13015 0ee40b798358c3886be6ac6719478154 342 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 219 342 6.0E-32 T 29-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDC59_RS03895 023ecce1b2162f92079ad6c9a815d8c9 344 Pfam PF16074 Type IV Pilus-assembly protein W 198 338 3.2E-32 T 29-03-2018 IPR032092 Type IV Pilus-assembly protein W GO:0043683 CDC59_RS03895 023ecce1b2162f92079ad6c9a815d8c9 344 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 13 35 3.5E-4 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS03895 023ecce1b2162f92079ad6c9a815d8c9 344 Pfam PF07963 Prokaryotic N-terminal methylation motif 11 35 2.3E-6 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS03895 023ecce1b2162f92079ad6c9a815d8c9 344 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 14 34 - T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS12275 e3aa7fd29c4b9b766a383ea6f02c67d7 180 Gene3D G3DSA:3.30.1450.10 100 174 6.8E-12 T 29-03-2018 CDC59_RS12275 e3aa7fd29c4b9b766a383ea6f02c67d7 180 Pfam PF04355 SmpA / OmlA family 104 169 1.0E-5 T 29-03-2018 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 CDC59_RS01055 b4b2bd3a17ab0586ff621e6233d96cdb 438 Pfam PF05161 MOFRL family 326 431 1.7E-35 T 29-03-2018 IPR007835 MOFRL domain Reactome: R-HSA-70350 CDC59_RS01055 b4b2bd3a17ab0586ff621e6233d96cdb 438 SUPERFAMILY SSF82544 20 437 1.31E-149 T 29-03-2018 CDC59_RS01055 b4b2bd3a17ab0586ff621e6233d96cdb 438 Pfam PF13660 Domain of unknown function (DUF4147) 25 247 8.7E-81 T 29-03-2018 IPR025286 MOFRL-associated domain Reactome: R-HSA-70350 CDC59_RS01055 b4b2bd3a17ab0586ff621e6233d96cdb 438 Gene3D G3DSA:3.40.50.10180 29 260 1.5E-86 T 29-03-2018 CDC59_RS01055 b4b2bd3a17ab0586ff621e6233d96cdb 438 Gene3D G3DSA:3.40.1480.10 261 438 4.2E-65 T 29-03-2018 IPR007835 MOFRL domain Reactome: R-HSA-70350 CDC59_RS08970 11f01973d8b06796e47dad5e74e59404 276 SUPERFAMILY SSF52141 92 270 6.87E-64 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CDC59_RS08970 11f01973d8b06796e47dad5e74e59404 276 SMART SM00986 117 264 9.0E-44 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CDC59_RS08970 11f01973d8b06796e47dad5e74e59404 276 Pfam PF03167 Uracil DNA glycosylase superfamily 117 263 9.8E-48 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CDC59_RS08970 11f01973d8b06796e47dad5e74e59404 276 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 103 264 4.2E-65 T 29-03-2018 IPR005273 Uracil-DNA glycosylase family 4 CDC59_RS08970 11f01973d8b06796e47dad5e74e59404 276 SMART SM00987 117 264 9.0E-44 T 29-03-2018 CDC59_RS08970 11f01973d8b06796e47dad5e74e59404 276 Gene3D G3DSA:3.40.470.10 91 275 2.3E-64 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CDC59_RS11030 317c45c9e4557ec74414bd62cb657281 338 Gene3D G3DSA:3.40.50.720 166 296 0.0012 T 29-03-2018 CDC59_RS11030 317c45c9e4557ec74414bd62cb657281 338 Gene3D G3DSA:3.90.180.10 1 165 3.6E-58 T 29-03-2018 CDC59_RS11030 317c45c9e4557ec74414bd62cb657281 338 SMART SM00829 14 329 0.0018 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CDC59_RS11030 317c45c9e4557ec74414bd62cb657281 338 TIGRFAM TIGR02822 adh_fam_2: zinc-binding alcohol dehydrogenase family protein 15 329 7.4E-100 T 29-03-2018 IPR014187 Alcohol dehydrogenase, zinc-binding type 2 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 CDC59_RS11030 317c45c9e4557ec74414bd62cb657281 338 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 63 77 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CDC59_RS11030 317c45c9e4557ec74414bd62cb657281 338 SUPERFAMILY SSF51735 142 295 7.05E-19 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS11030 317c45c9e4557ec74414bd62cb657281 338 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 137 1.3E-32 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CDC59_RS11030 317c45c9e4557ec74414bd62cb657281 338 SUPERFAMILY SSF50129 5 163 1.98E-52 T 29-03-2018 IPR011032 GroES-like CDC59_RS03055 7642597f5fc560399a1d987e11436e7a 698 Gene3D G3DSA:3.40.50.740 63 160 2.9E-16 T 29-03-2018 CDC59_RS03055 7642597f5fc560399a1d987e11436e7a 698 SUPERFAMILY SSF50692 539 693 9.04E-40 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain CDC59_RS03055 7642597f5fc560399a1d987e11436e7a 698 Gene3D G3DSA:3.40.228.10 161 243 2.0E-23 T 29-03-2018 CDC59_RS03055 7642597f5fc560399a1d987e11436e7a 698 Pfam PF01568 Molydopterin dinucleotide binding domain 579 687 1.1E-24 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CDC59_RS03055 7642597f5fc560399a1d987e11436e7a 698 Gene3D G3DSA:2.40.40.20 534 698 5.8E-35 T 29-03-2018 CDC59_RS03055 7642597f5fc560399a1d987e11436e7a 698 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 4 58 1.6E-13 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS03055 7642597f5fc560399a1d987e11436e7a 698 Gene3D G3DSA:3.40.50.740 244 533 3.3E-40 T 29-03-2018 CDC59_RS03055 7642597f5fc560399a1d987e11436e7a 698 SMART SM00926 3 58 2.7E-20 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS03055 7642597f5fc560399a1d987e11436e7a 698 Pfam PF00384 Molybdopterin oxidoreductase 61 478 2.7E-51 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS03055 7642597f5fc560399a1d987e11436e7a 698 SUPERFAMILY SSF53706 4 566 1.31E-166 T 29-03-2018 CDC59_RS03055 7642597f5fc560399a1d987e11436e7a 698 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 423 440 - T 29-03-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 CDC59_RS03055 7642597f5fc560399a1d987e11436e7a 698 Gene3D G3DSA:2.20.25.90 1 62 1.1E-18 T 29-03-2018 CDC59_RS02325 78a3712de0fef2ac29a7d2c3eafd633e 60 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 6 59 5.0E-25 T 29-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS02325 78a3712de0fef2ac29a7d2c3eafd633e 60 Gene3D G3DSA:3.30.1390.20 6 59 5.2E-23 T 29-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CDC59_RS02325 78a3712de0fef2ac29a7d2c3eafd633e 60 PIRSF PIRSF002211 1 60 8.3E-27 T 29-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS02325 78a3712de0fef2ac29a7d2c3eafd633e 60 Pfam PF00327 Ribosomal protein L30p/L7e 7 56 1.1E-18 T 29-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CDC59_RS02325 78a3712de0fef2ac29a7d2c3eafd633e 60 SUPERFAMILY SSF55129 4 58 2.09E-20 T 29-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CDC59_RS02325 78a3712de0fef2ac29a7d2c3eafd633e 60 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 3 60 20.308 T 29-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS18075 d0b026a8f751c1f16a402df75a7d07cb 837 TIGRFAM TIGR01901 adhes_NPXG: filamentous hemagglutinin family N-terminal domain 52 130 2.7E-21 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal CDC59_RS18075 d0b026a8f751c1f16a402df75a7d07cb 837 Pfam PF05860 haemagglutination activity domain 20 134 1.8E-28 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal CDC59_RS18075 d0b026a8f751c1f16a402df75a7d07cb 837 Gene3D G3DSA:2.160.20.10 23 318 2.9E-38 T 29-03-2018 IPR012334 Pectin lyase fold CDC59_RS18075 d0b026a8f751c1f16a402df75a7d07cb 837 SMART SM00912 35 135 9.3E-18 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal CDC59_RS18075 d0b026a8f751c1f16a402df75a7d07cb 837 SUPERFAMILY SSF51126 329 341 2.51E-34 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CDC59_RS18075 d0b026a8f751c1f16a402df75a7d07cb 837 SUPERFAMILY SSF51126 27 283 2.51E-34 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CDC59_RS09180 a45c5a55a1750d349903e59288616d3e 393 SUPERFAMILY SSF51735 3 150 2.81E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS09180 a45c5a55a1750d349903e59288616d3e 393 SUPERFAMILY SSF55347 126 267 6.54E-62 T 29-03-2018 CDC59_RS09180 a45c5a55a1750d349903e59288616d3e 393 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 4 385 47.951 T 29-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CDC59_RS09180 a45c5a55a1750d349903e59288616d3e 393 Pfam PF13288 DXP reductoisomerase C-terminal domain 264 380 7.9E-42 T 29-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CDC59_RS09180 a45c5a55a1750d349903e59288616d3e 393 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 146 232 1.1E-39 T 29-03-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CDC59_RS09180 a45c5a55a1750d349903e59288616d3e 393 PIRSF PIRSF006205 1 392 1.8E-157 T 29-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CDC59_RS09180 a45c5a55a1750d349903e59288616d3e 393 Gene3D G3DSA:1.10.1740.10 305 389 3.1E-30 T 29-03-2018 CDC59_RS09180 a45c5a55a1750d349903e59288616d3e 393 SUPERFAMILY SSF69055 296 386 6.8E-31 T 29-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CDC59_RS09180 a45c5a55a1750d349903e59288616d3e 393 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 2 387 2.5E-155 T 29-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CDC59_RS09180 a45c5a55a1750d349903e59288616d3e 393 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 4 132 2.0E-46 T 29-03-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CDC59_RS09180 a45c5a55a1750d349903e59288616d3e 393 Gene3D G3DSA:3.40.50.720 1 150 1.7E-50 T 29-03-2018 CDC59_RS18545 e5eecdafa2aac87ba38f860bf2662fa6 155 Pfam PF07007 Lysozyme inhibitor LprI 55 140 2.8E-12 T 29-03-2018 IPR009739 Lysozyme inhibitor LprI, N-terminal CDC59_RS11455 5ae2f07f60e51694de54118cc15f7b7e 433 PIRSF PIRSF001369 41 433 1.1E-160 T 29-03-2018 IPR024176 Citrate synthase, bacterial-type CDC59_RS11455 5ae2f07f60e51694de54118cc15f7b7e 433 SUPERFAMILY SSF48256 9 433 2.88E-162 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CDC59_RS11455 5ae2f07f60e51694de54118cc15f7b7e 433 Gene3D G3DSA:1.10.580.10 313 409 2.5E-7 T 29-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain CDC59_RS11455 5ae2f07f60e51694de54118cc15f7b7e 433 Pfam PF00285 Citrate synthase, C-terminal domain 50 416 2.4E-132 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CDC59_RS11455 5ae2f07f60e51694de54118cc15f7b7e 433 PRINTS PR00143 Citrate synthase signature 223 238 6.3E-54 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CDC59_RS11455 5ae2f07f60e51694de54118cc15f7b7e 433 PRINTS PR00143 Citrate synthase signature 364 380 6.3E-54 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CDC59_RS11455 5ae2f07f60e51694de54118cc15f7b7e 433 PRINTS PR00143 Citrate synthase signature 245 273 6.3E-54 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CDC59_RS11455 5ae2f07f60e51694de54118cc15f7b7e 433 PRINTS PR00143 Citrate synthase signature 384 398 6.3E-54 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CDC59_RS11455 5ae2f07f60e51694de54118cc15f7b7e 433 PRINTS PR00143 Citrate synthase signature 169 182 6.3E-54 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CDC59_RS11455 5ae2f07f60e51694de54118cc15f7b7e 433 PRINTS PR00143 Citrate synthase signature 300 320 6.3E-54 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CDC59_RS11455 5ae2f07f60e51694de54118cc15f7b7e 433 ProSitePatterns PS00480 Citrate synthase signature. 307 319 - T 29-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CDC59_RS11455 5ae2f07f60e51694de54118cc15f7b7e 433 Gene3D G3DSA:1.10.580.10 55 312 6.5E-89 T 29-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain CDC59_RS11455 5ae2f07f60e51694de54118cc15f7b7e 433 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 18 426 3.5E-245 T 29-03-2018 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 CDC59_RS13425 887d033ba846351b456e7f6c069b5093 232 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 12 191 1.8E-64 T 29-03-2018 IPR022301 Integral membrane protein YjbE CDC59_RS13425 887d033ba846351b456e7f6c069b5093 232 Pfam PF03741 Integral membrane protein TerC family 15 190 1.1E-42 T 29-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 CDC59_RS22385 3840414383e3b8f54899fbf46b5cb381 150 Gene3D G3DSA:1.10.10.10 1 52 2.7E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS22385 3840414383e3b8f54899fbf46b5cb381 150 SUPERFAMILY SSF54909 61 150 7.51E-17 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CDC59_RS22385 3840414383e3b8f54899fbf46b5cb381 150 SMART SM00344 1 110 4.1E-45 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CDC59_RS22385 3840414383e3b8f54899fbf46b5cb381 150 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 29-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site CDC59_RS22385 3840414383e3b8f54899fbf46b5cb381 150 SUPERFAMILY SSF46785 1 60 4.86E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS22385 3840414383e3b8f54899fbf46b5cb381 150 Pfam PF01037 Lrp/AsnC ligand binding domain 67 140 2.8E-16 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CDC59_RS22385 3840414383e3b8f54899fbf46b5cb381 150 Gene3D G3DSA:3.30.70.920 53 138 1.0E-19 T 29-03-2018 CDC59_RS22385 3840414383e3b8f54899fbf46b5cb381 150 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 47 9.9E-20 T 29-03-2018 CDC59_RS22385 3840414383e3b8f54899fbf46b5cb381 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 1.4E-18 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CDC59_RS22385 3840414383e3b8f54899fbf46b5cb381 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 1.4E-18 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CDC59_RS22385 3840414383e3b8f54899fbf46b5cb381 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 1.4E-18 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CDC59_RS08725 b50bb148c7164872d094857438694304 351 Gene3D G3DSA:3.90.25.10 193 311 3.0E-18 T 29-03-2018 CDC59_RS08725 b50bb148c7164872d094857438694304 351 Gene3D G3DSA:3.40.50.720 1 192 1.3E-18 T 29-03-2018 CDC59_RS08725 b50bb148c7164872d094857438694304 351 Gene3D G3DSA:3.90.25.10 312 351 7.2E-7 T 29-03-2018 CDC59_RS08725 b50bb148c7164872d094857438694304 351 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 256 3.0E-47 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CDC59_RS08725 b50bb148c7164872d094857438694304 351 SUPERFAMILY SSF51735 2 342 1.31E-66 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS07250 57e2dcc40b8e36ac1d384a8a25c87171 1017 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 423 5.6E-160 T 29-03-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 CDC59_RS07250 57e2dcc40b8e36ac1d384a8a25c87171 1017 Pfam PF00575 S1 RNA binding domain 36 117 1.1E-10 T 29-03-2018 IPR003029 S1 domain GO:0003676 CDC59_RS07250 57e2dcc40b8e36ac1d384a8a25c87171 1017 Hamap MF_00970 Ribonuclease E [rne]. 1 998 35.116 T 29-03-2018 IPR028878 Ribonuclease E GO:0006396|GO:0008995 CDC59_RS07250 57e2dcc40b8e36ac1d384a8a25c87171 1017 Gene3D G3DSA:2.40.50.140 32 123 8.7E-30 T 29-03-2018 CDC59_RS07250 57e2dcc40b8e36ac1d384a8a25c87171 1017 Pfam PF10150 Ribonuclease E/G family 120 389 8.3E-94 T 29-03-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 CDC59_RS07250 57e2dcc40b8e36ac1d384a8a25c87171 1017 SUPERFAMILY SSF50249 39 124 1.03E-17 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDC59_RS07250 57e2dcc40b8e36ac1d384a8a25c87171 1017 SMART SM00316 37 118 9.8E-10 T 29-03-2018 IPR022967 RNA-binding domain, S1 CDC59_RS21595 2417912951f3af02a8e57597d9a5b565 427 Gene3D G3DSA:1.10.530.10 230 355 2.5E-32 T 29-03-2018 CDC59_RS21595 2417912951f3af02a8e57597d9a5b565 427 Gene3D G3DSA:1.10.8.350 122 224 2.4E-32 T 29-03-2018 CDC59_RS21595 2417912951f3af02a8e57597d9a5b565 427 Pfam PF13406 Transglycosylase SLT domain 56 348 6.4E-106 T 29-03-2018 IPR031304 Transglycosylase SLT domain 2 CDC59_RS21595 2417912951f3af02a8e57597d9a5b565 427 TIGRFAM TIGR02283 MltB_2: lytic murein transglycosylase 56 352 6.6E-112 T 29-03-2018 IPR011970 Lytic murein transglycosylase CDC59_RS21595 2417912951f3af02a8e57597d9a5b565 427 Pfam PF01471 Putative peptidoglycan binding domain 371 425 3.4E-13 T 29-03-2018 IPR002477 Peptidoglycan binding-like CDC59_RS21595 2417912951f3af02a8e57597d9a5b565 427 Gene3D G3DSA:1.10.101.10 356 427 1.2E-14 T 29-03-2018 IPR002477 Peptidoglycan binding-like CDC59_RS21595 2417912951f3af02a8e57597d9a5b565 427 SUPERFAMILY SSF53955 51 353 2.33E-95 T 29-03-2018 IPR023346 Lysozyme-like domain CDC59_RS21595 2417912951f3af02a8e57597d9a5b565 427 SUPERFAMILY SSF47090 357 425 2.75E-16 T 29-03-2018 IPR002477 Peptidoglycan binding-like CDC59_RS13880 47152ce6b2c11a43ade5277301cfdcdd 399 Pfam PF02803 Thiolase, C-terminal domain 276 398 6.0E-43 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CDC59_RS13880 47152ce6b2c11a43ade5277301cfdcdd 399 ProSitePatterns PS00737 Thiolases signature 2. 345 361 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CDC59_RS13880 47152ce6b2c11a43ade5277301cfdcdd 399 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 10 397 4.8E-142 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CDC59_RS13880 47152ce6b2c11a43ade5277301cfdcdd 399 SUPERFAMILY SSF53901 4 273 1.25E-71 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS13880 47152ce6b2c11a43ade5277301cfdcdd 399 Gene3D G3DSA:3.40.47.10 280 396 2.9E-31 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS13880 47152ce6b2c11a43ade5277301cfdcdd 399 SUPERFAMILY SSF53901 277 398 3.52E-42 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS13880 47152ce6b2c11a43ade5277301cfdcdd 399 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 91 109 - T 29-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CDC59_RS13880 47152ce6b2c11a43ade5277301cfdcdd 399 Gene3D G3DSA:3.40.47.10 1 279 2.6E-52 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS13880 47152ce6b2c11a43ade5277301cfdcdd 399 ProSitePatterns PS00099 Thiolases active site. 380 393 - T 29-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CDC59_RS13880 47152ce6b2c11a43ade5277301cfdcdd 399 Pfam PF00108 Thiolase, N-terminal domain 9 268 2.7E-72 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CDC59_RS13880 47152ce6b2c11a43ade5277301cfdcdd 399 PIRSF PIRSF000429 2 399 3.3E-125 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CDC59_RS00410 75b1150aeba6bd170c255abf039c127b 261 Pfam PF03988 Repeat of Unknown Function (DUF347) 79 129 6.7E-18 T 29-03-2018 IPR007136 Protein of unknown function DUF347 CDC59_RS00410 75b1150aeba6bd170c255abf039c127b 261 Pfam PF03988 Repeat of Unknown Function (DUF347) 24 74 6.2E-17 T 29-03-2018 IPR007136 Protein of unknown function DUF347 CDC59_RS00410 75b1150aeba6bd170c255abf039c127b 261 Pfam PF03988 Repeat of Unknown Function (DUF347) 199 253 1.6E-13 T 29-03-2018 IPR007136 Protein of unknown function DUF347 CDC59_RS00410 75b1150aeba6bd170c255abf039c127b 261 Pfam PF03988 Repeat of Unknown Function (DUF347) 144 193 1.9E-13 T 29-03-2018 IPR007136 Protein of unknown function DUF347 CDC59_RS08945 fc54222bc3bfe7e8923847593993af47 526 Gene3D G3DSA:3.20.20.360 78 411 2.6E-111 T 29-03-2018 CDC59_RS08945 fc54222bc3bfe7e8923847593993af47 526 SUPERFAMILY SSF51645 5 526 1.44E-187 T 29-03-2018 IPR011076 Malate synthase-like GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 CDC59_RS08945 fc54222bc3bfe7e8923847593993af47 526 Gene3D G3DSA:1.20.1220.12 412 526 1.8E-42 T 29-03-2018 CDC59_RS08945 fc54222bc3bfe7e8923847593993af47 526 ProSitePatterns PS00510 Malate synthase signature. 263 278 - T 29-03-2018 IPR019830 Malate synthase, conserved site GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 CDC59_RS08945 fc54222bc3bfe7e8923847593993af47 526 TIGRFAM TIGR01344 malate_syn_A: malate synthase A 22 526 2.8E-229 T 29-03-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 CDC59_RS08945 fc54222bc3bfe7e8923847593993af47 526 Pfam PF01274 Malate synthase 10 526 5.0E-202 T 29-03-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 CDC59_RS08945 fc54222bc3bfe7e8923847593993af47 526 PIRSF PIRSF001363 1 526 2.1E-248 T 29-03-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 CDC59_RS05735 103743e17b6e30f9a58a3d195bd7e88d 369 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 81 267 8.5E-16 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CDC59_RS05735 103743e17b6e30f9a58a3d195bd7e88d 369 SUPERFAMILY SSF111369 69 243 1.16E-21 T 29-03-2018 CDC59_RS05735 103743e17b6e30f9a58a3d195bd7e88d 369 Gene3D G3DSA:1.10.287.470 131 175 6.8E-7 T 29-03-2018 CDC59_RS05735 103743e17b6e30f9a58a3d195bd7e88d 369 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 56 359 2.2E-55 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 CDC59_RS05735 103743e17b6e30f9a58a3d195bd7e88d 369 Gene3D G3DSA:2.40.50.100 176 327 0.3 T 29-03-2018 CDC59_RS05735 103743e17b6e30f9a58a3d195bd7e88d 369 Gene3D G3DSA:3.90.1170.30 22 130 1.1E-4 T 29-03-2018 CDC59_RS23750 a35ed3bb5478f84f7e51c757e27467ee 294 Gene3D G3DSA:3.40.50.720 1 286 3.6E-20 T 29-03-2018 CDC59_RS23750 a35ed3bb5478f84f7e51c757e27467ee 294 SUPERFAMILY SSF51735 3 252 8.49E-35 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS23750 a35ed3bb5478f84f7e51c757e27467ee 294 Pfam PF13460 NAD(P)H-binding 6 117 1.4E-15 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS20195 54ae0c6f6d4740fe36f22a62222b92f9 690 PIRSF PIRSF005419 1 690 1.3E-223 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CDC59_RS20195 54ae0c6f6d4740fe36f22a62222b92f9 690 TIGRFAM TIGR01399 hrcV: type III secretion protein, HrcV family 12 687 9.4E-252 T 29-03-2018 IPR006302 Type III secretion protein HrcV GO:0015031|GO:0016021 CDC59_RS20195 54ae0c6f6d4740fe36f22a62222b92f9 690 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 30 43 6.3E-52 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CDC59_RS20195 54ae0c6f6d4740fe36f22a62222b92f9 690 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 178 195 6.3E-52 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CDC59_RS20195 54ae0c6f6d4740fe36f22a62222b92f9 690 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 67 86 6.3E-52 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CDC59_RS20195 54ae0c6f6d4740fe36f22a62222b92f9 690 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 229 243 6.3E-52 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CDC59_RS20195 54ae0c6f6d4740fe36f22a62222b92f9 690 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 129 145 6.3E-52 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CDC59_RS20195 54ae0c6f6d4740fe36f22a62222b92f9 690 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 148 166 6.3E-52 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CDC59_RS20195 54ae0c6f6d4740fe36f22a62222b92f9 690 ProSitePatterns PS00994 Bacterial export FHIPEP family signature. 134 157 - T 29-03-2018 IPR025505 FHIPEP conserved site CDC59_RS20195 54ae0c6f6d4740fe36f22a62222b92f9 690 Pfam PF00771 FHIPEP family 23 677 2.4E-214 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CDC59_RS21320 a00bb463cd53bcc1f556623596a4b711 125 SMART SM00422 1 72 6.1E-19 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CDC59_RS21320 a00bb463cd53bcc1f556623596a4b711 125 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 1.8E-5 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CDC59_RS21320 a00bb463cd53bcc1f556623596a4b711 125 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 1.8E-5 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CDC59_RS21320 a00bb463cd53bcc1f556623596a4b711 125 SUPERFAMILY SSF46955 1 116 9.89E-26 T 29-03-2018 IPR009061 Putative DNA-binding domain CDC59_RS21320 a00bb463cd53bcc1f556623596a4b711 125 Gene3D G3DSA:1.10.1660.10 59 123 1.6E-11 T 29-03-2018 CDC59_RS21320 a00bb463cd53bcc1f556623596a4b711 125 Gene3D G3DSA:1.10.1660.10 1 58 4.0E-20 T 29-03-2018 CDC59_RS21320 a00bb463cd53bcc1f556623596a4b711 125 Pfam PF13411 MerR HTH family regulatory protein 1 69 1.9E-15 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CDC59_RS16555 f11508de5f80dd6bcff2309468089b00 144 TIGRFAM TIGR01710 typeII_sec_gspG: type II secretion system protein G 15 144 6.5E-51 T 29-03-2018 IPR010054 General secretion pathway protein G GO:0008565|GO:0015627|GO:0015628 CDC59_RS16555 f11508de5f80dd6bcff2309468089b00 144 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 15 36 7.1E-9 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS16555 f11508de5f80dd6bcff2309468089b00 144 SUPERFAMILY SSF54523 43 143 1.88E-33 T 29-03-2018 CDC59_RS16555 f11508de5f80dd6bcff2309468089b00 144 Pfam PF07963 Prokaryotic N-terminal methylation motif 14 35 9.2E-8 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS16555 f11508de5f80dd6bcff2309468089b00 144 Pfam PF08334 Type II secretion system (T2SS), protein G 40 144 3.2E-39 T 29-03-2018 IPR013545 Type II secretion system protein G CDC59_RS16555 f11508de5f80dd6bcff2309468089b00 144 PRINTS PR00813 Bacterial general secretion pathway protein G signature 52 70 5.0E-15 T 29-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 CDC59_RS16555 f11508de5f80dd6bcff2309468089b00 144 PRINTS PR00813 Bacterial general secretion pathway protein G signature 16 41 5.0E-15 T 29-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 CDC59_RS16555 f11508de5f80dd6bcff2309468089b00 144 Gene3D G3DSA:3.30.700.10 30 143 6.7E-24 T 29-03-2018 CDC59_RS05075 df59afa74416ed2dffb54c86552687f9 249 SMART SM00244 21 178 3.3E-61 T 29-03-2018 IPR001107 Band 7 domain CDC59_RS05075 df59afa74416ed2dffb54c86552687f9 249 Pfam PF01145 SPFH domain / Band 7 family 26 194 5.5E-34 T 29-03-2018 IPR001107 Band 7 domain CDC59_RS05075 df59afa74416ed2dffb54c86552687f9 249 SUPERFAMILY SSF117892 52 185 1.83E-42 T 29-03-2018 IPR001107 Band 7 domain CDC59_RS05075 df59afa74416ed2dffb54c86552687f9 249 PRINTS PR00721 Stomatin signature 110 127 1.8E-62 T 29-03-2018 IPR001972 Stomatin family GO:0016020 CDC59_RS05075 df59afa74416ed2dffb54c86552687f9 249 PRINTS PR00721 Stomatin signature 130 153 1.8E-62 T 29-03-2018 IPR001972 Stomatin family GO:0016020 CDC59_RS05075 df59afa74416ed2dffb54c86552687f9 249 PRINTS PR00721 Stomatin signature 198 221 1.8E-62 T 29-03-2018 IPR001972 Stomatin family GO:0016020 CDC59_RS05075 df59afa74416ed2dffb54c86552687f9 249 PRINTS PR00721 Stomatin signature 154 172 1.8E-62 T 29-03-2018 IPR001972 Stomatin family GO:0016020 CDC59_RS05075 df59afa74416ed2dffb54c86552687f9 249 PRINTS PR00721 Stomatin signature 75 96 1.8E-62 T 29-03-2018 IPR001972 Stomatin family GO:0016020 CDC59_RS05075 df59afa74416ed2dffb54c86552687f9 249 PRINTS PR00721 Stomatin signature 28 50 1.8E-62 T 29-03-2018 IPR001972 Stomatin family GO:0016020 CDC59_RS05075 df59afa74416ed2dffb54c86552687f9 249 PRINTS PR00721 Stomatin signature 173 194 1.8E-62 T 29-03-2018 IPR001972 Stomatin family GO:0016020 CDC59_RS12920 7fd5663fb78f258cfc8b1df450da6d56 206 Pfam PF01618 MotA/TolQ/ExbB proton channel family 68 190 1.8E-33 T 29-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 CDC59_RS07810 a58c400bd5971a8a1d07a4b701752cfd 297 SUPERFAMILY SSF53850 89 295 3.88E-43 T 29-03-2018 CDC59_RS07810 a58c400bd5971a8a1d07a4b701752cfd 297 Gene3D G3DSA:3.40.190.10 87 177 3.1E-24 T 29-03-2018 CDC59_RS07810 a58c400bd5971a8a1d07a4b701752cfd 297 Gene3D G3DSA:3.40.190.10 178 263 6.0E-22 T 29-03-2018 CDC59_RS07810 a58c400bd5971a8a1d07a4b701752cfd 297 Pfam PF03466 LysR substrate binding domain 88 293 4.4E-42 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS07810 a58c400bd5971a8a1d07a4b701752cfd 297 Gene3D G3DSA:1.10.10.10 1 85 3.2E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS07810 a58c400bd5971a8a1d07a4b701752cfd 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 3.6E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS07810 a58c400bd5971a8a1d07a4b701752cfd 297 SUPERFAMILY SSF46785 4 113 7.89E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS22030 fbe58436c1dd2485e89c33929f66f63a 918 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 17 35 - T 29-03-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 CDC59_RS22030 fbe58436c1dd2485e89c33929f66f63a 918 SUPERFAMILY SSF50692 584 728 1.81E-43 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain CDC59_RS22030 fbe58436c1dd2485e89c33929f66f63a 918 Gene3D G3DSA:3.40.50.740 72 266 5.1E-50 T 29-03-2018 CDC59_RS22030 fbe58436c1dd2485e89c33929f66f63a 918 PIRSF PIRSF036643 3 740 3.2E-146 T 29-03-2018 CDC59_RS22030 fbe58436c1dd2485e89c33929f66f63a 918 SMART SM00926 12 66 1.9E-18 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS22030 fbe58436c1dd2485e89c33929f66f63a 918 Pfam PF04324 BFD-like [2Fe-2S] binding domain 861 909 4.8E-12 T 29-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain CDC59_RS22030 fbe58436c1dd2485e89c33929f66f63a 918 Gene3D G3DSA:2.40.40.20 573 728 1.1E-42 T 29-03-2018 CDC59_RS22030 fbe58436c1dd2485e89c33929f66f63a 918 SUPERFAMILY SSF53706 13 614 6.02E-185 T 29-03-2018 CDC59_RS22030 fbe58436c1dd2485e89c33929f66f63a 918 Pfam PF01568 Molydopterin dinucleotide binding domain 612 723 2.4E-29 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CDC59_RS22030 fbe58436c1dd2485e89c33929f66f63a 918 Gene3D G3DSA:3.40.50.740 276 572 2.3E-74 T 29-03-2018 CDC59_RS22030 fbe58436c1dd2485e89c33929f66f63a 918 Pfam PF00384 Molybdopterin oxidoreductase 69 510 1.1E-76 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS22030 fbe58436c1dd2485e89c33929f66f63a 918 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 14 65 1.4E-18 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS22030 fbe58436c1dd2485e89c33929f66f63a 918 Gene3D G3DSA:2.20.25.90 9 67 1.2E-18 T 29-03-2018 CDC59_RS17800 e998ef4a790d7a4c690a2a6f5d273edf 533 Gene3D G3DSA:3.40.50.2000 5 260 1.1E-9 T 29-03-2018 CDC59_RS17800 e998ef4a790d7a4c690a2a6f5d273edf 533 Pfam PF00534 Glycosyl transferases group 1 300 443 1.9E-17 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CDC59_RS17800 e998ef4a790d7a4c690a2a6f5d273edf 533 Gene3D G3DSA:3.40.50.2000 261 475 9.0E-35 T 29-03-2018 CDC59_RS17800 e998ef4a790d7a4c690a2a6f5d273edf 533 TIGRFAM TIGR02095 glgA: glycogen/starch synthase, ADP-glucose type 4 478 5.6E-150 T 29-03-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 CDC59_RS17800 e998ef4a790d7a4c690a2a6f5d273edf 533 Pfam PF08323 Starch synthase catalytic domain 4 236 5.8E-65 T 29-03-2018 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 CDC59_RS17800 e998ef4a790d7a4c690a2a6f5d273edf 533 Hamap MF_00484 Glycogen synthase [glgA]. 3 479 38.939 T 29-03-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 CDC59_RS17800 e998ef4a790d7a4c690a2a6f5d273edf 533 SUPERFAMILY SSF53756 4 481 6.63E-104 T 29-03-2018 CDC59_RS09600 ca25664bed6119f9c9dbcbe64fcea189 229 PIRSF PIRSF006755 4 227 6.1E-64 T 29-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 CDC59_RS09600 ca25664bed6119f9c9dbcbe64fcea189 229 SUPERFAMILY SSF52540 7 215 5.9E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS09600 ca25664bed6119f9c9dbcbe64fcea189 229 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 8 178 9.1E-46 T 29-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 CDC59_RS09600 ca25664bed6119f9c9dbcbe64fcea189 229 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 4 220 28.841 T 29-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 CDC59_RS09600 ca25664bed6119f9c9dbcbe64fcea189 229 Gene3D G3DSA:3.40.50.300 3 222 2.8E-59 T 29-03-2018 CDC59_RS09600 ca25664bed6119f9c9dbcbe64fcea189 229 Pfam PF13500 AAA domain 8 211 6.9E-40 T 29-03-2018 CDC59_RS21400 ee3ac958a53740b7e4da430a7bfbc1c5 578 Pfam PF17287 POTRA domain 164 218 9.0E-21 T 29-03-2018 IPR035251 ShlB, POTRA domain CDC59_RS21400 ee3ac958a53740b7e4da430a7bfbc1c5 578 Pfam PF08479 POTRA domain, ShlB-type 84 163 1.6E-22 T 29-03-2018 IPR013686 Polypeptide-transport-associated, ShlB-type CDC59_RS21400 ee3ac958a53740b7e4da430a7bfbc1c5 578 Gene3D G3DSA:3.10.20.310 90 163 2.3E-9 T 29-03-2018 CDC59_RS21400 ee3ac958a53740b7e4da430a7bfbc1c5 578 PIRSF PIRSF029745 10 578 6.3E-158 T 29-03-2018 IPR027282 Two partner secretion pathway transporter GO:0015031 CDC59_RS21400 ee3ac958a53740b7e4da430a7bfbc1c5 578 Pfam PF03865 Haemolysin secretion/activation protein ShlB/FhaC/HecB 227 542 4.2E-109 T 29-03-2018 IPR005565 Haemolysin activator HlyB, C-terminal CDC59_RS21400 ee3ac958a53740b7e4da430a7bfbc1c5 578 Gene3D G3DSA:2.40.160.50 191 578 1.0E-46 T 29-03-2018 CDC59_RS22455 16b38a53f8c56c212ad03cfeeb0e4376 529 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 76 489 2.7E-78 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS22455 16b38a53f8c56c212ad03cfeeb0e4376 529 Gene3D G3DSA:1.20.210.10 65 519 3.9E-57 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS22455 16b38a53f8c56c212ad03cfeeb0e4376 529 SUPERFAMILY SSF81442 73 516 4.97E-96 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS12820 0cf99ca916150777d209d865da38d9f9 441 Pfam PF07804 HipA-like C-terminal domain 176 386 2.5E-12 T 29-03-2018 IPR012893 HipA-like, C-terminal CDC59_RS12820 0cf99ca916150777d209d865da38d9f9 441 Pfam PF13657 HipA N-terminal domain 2 70 1.4E-7 T 29-03-2018 IPR017508 HipA, N-terminal subdomain 1 CDC59_RS05385 c80ace8d11fd47a7d536576b38cc159b 252 Pfam PF05726 Pirin C-terminal cupin domain 172 248 5.9E-5 T 29-03-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 CDC59_RS05385 c80ace8d11fd47a7d536576b38cc159b 252 SUPERFAMILY SSF51182 19 248 9.49E-40 T 29-03-2018 IPR011051 RmlC-like cupin domain CDC59_RS05385 c80ace8d11fd47a7d536576b38cc159b 252 Gene3D G3DSA:2.60.120.10 143 247 1.2E-19 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CDC59_RS05385 c80ace8d11fd47a7d536576b38cc159b 252 Gene3D G3DSA:2.60.120.10 18 142 9.5E-27 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CDC59_RS05385 c80ace8d11fd47a7d536576b38cc159b 252 Pfam PF02678 Pirin 48 119 5.1E-16 T 29-03-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 CDC59_RS05385 c80ace8d11fd47a7d536576b38cc159b 252 PIRSF PIRSF006232 8 252 2.0E-52 T 29-03-2018 IPR012093 Pirin Reactome: R-HSA-8935690 CDC59_RS12910 599a67c3e677fc235a7a577bd0de1533 192 SUPERFAMILY SSF54719 82 191 1.7E-46 T 29-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CDC59_RS12910 599a67c3e677fc235a7a577bd0de1533 192 SUPERFAMILY SSF46609 1 84 5.63E-36 T 29-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CDC59_RS12910 599a67c3e677fc235a7a577bd0de1533 192 Gene3D G3DSA:1.10.287.990 20 82 3.2E-26 T 29-03-2018 CDC59_RS12910 599a67c3e677fc235a7a577bd0de1533 192 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 81 2.2E-34 T 29-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CDC59_RS12910 599a67c3e677fc235a7a577bd0de1533 192 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 157 164 - T 29-03-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CDC59_RS12910 599a67c3e677fc235a7a577bd0de1533 192 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 89 189 8.6E-42 T 29-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CDC59_RS12910 599a67c3e677fc235a7a577bd0de1533 192 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 3.9E-23 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CDC59_RS12910 599a67c3e677fc235a7a577bd0de1533 192 PRINTS PR01703 Manganese superoxide dismutase signature 65 78 3.9E-23 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CDC59_RS12910 599a67c3e677fc235a7a577bd0de1533 192 PRINTS PR01703 Manganese superoxide dismutase signature 155 167 3.9E-23 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CDC59_RS12910 599a67c3e677fc235a7a577bd0de1533 192 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 3.9E-23 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CDC59_RS12910 599a67c3e677fc235a7a577bd0de1533 192 PRINTS PR01703 Manganese superoxide dismutase signature 118 126 3.9E-23 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CDC59_RS12910 599a67c3e677fc235a7a577bd0de1533 192 PIRSF PIRSF000349 1 192 7.7E-89 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CDC59_RS19340 0acc83cd7d40c808f5b24b4d7033031f 223 Gene3D G3DSA:3.40.50.10070 32 187 9.9E-13 T 29-03-2018 CDC59_RS19340 0acc83cd7d40c808f5b24b4d7033031f 223 Pfam PF05643 Putative bacterial lipoprotein (DUF799) 13 216 2.4E-94 T 29-03-2018 IPR008517 Protein of unknown function DUF799 CDC59_RS10100 d18684a274d2fc5137503d212eedfb6a 209 Pfam PF08896 Domain of unknown function (DUF1842) 7 120 2.1E-47 T 29-03-2018 IPR014992 Domain of unknown function DUF1842 CDC59_RS10100 d18684a274d2fc5137503d212eedfb6a 209 Pfam PF08898 Domain of unknown function (DUF1843) 156 207 4.8E-22 T 29-03-2018 IPR014994 Domain of unknown function DUF1843 CDC59_RS22780 c81bdfef5dc4c21d01fd845363aaa544 151 Gene3D G3DSA:3.40.50.620 1 151 4.8E-34 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDC59_RS22780 c81bdfef5dc4c21d01fd845363aaa544 151 PRINTS PR01438 Universal stress protein signature 2 20 1.4E-20 T 29-03-2018 IPR006015 Universal stress protein A CDC59_RS22780 c81bdfef5dc4c21d01fd845363aaa544 151 PRINTS PR01438 Universal stress protein signature 106 118 1.4E-20 T 29-03-2018 IPR006015 Universal stress protein A CDC59_RS22780 c81bdfef5dc4c21d01fd845363aaa544 151 PRINTS PR01438 Universal stress protein signature 124 146 1.4E-20 T 29-03-2018 IPR006015 Universal stress protein A CDC59_RS22780 c81bdfef5dc4c21d01fd845363aaa544 151 SUPERFAMILY SSF52402 1 148 6.11E-34 T 29-03-2018 CDC59_RS22780 c81bdfef5dc4c21d01fd845363aaa544 151 Pfam PF00582 Universal stress protein family 1 146 4.0E-32 T 29-03-2018 IPR006016 UspA GO:0006950 CDC59_RS08825 0c165bb8cbd9c74eca3afc89c37f5f0c 340 SUPERFAMILY SSF53850 44 275 1.01E-46 T 29-03-2018 CDC59_RS08825 0c165bb8cbd9c74eca3afc89c37f5f0c 340 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 48 328 4.0E-71 T 29-03-2018 IPR010067 Aliphatic sulfonates-binding protein GO:0016020|GO:0042626 CDC59_RS08825 0c165bb8cbd9c74eca3afc89c37f5f0c 340 Gene3D G3DSA:3.40.190.10 149 333 1.1E-32 T 29-03-2018 CDC59_RS08825 0c165bb8cbd9c74eca3afc89c37f5f0c 340 Pfam PF13379 NMT1-like family 44 271 1.1E-12 T 29-03-2018 CDC59_RS08825 0c165bb8cbd9c74eca3afc89c37f5f0c 340 SMART SM00062 47 266 1.6E-17 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CDC59_RS08825 0c165bb8cbd9c74eca3afc89c37f5f0c 340 Gene3D G3DSA:3.40.190.10 44 148 1.7E-14 T 29-03-2018 CDC59_RS22730 e273583508171c2a216eefda934c8a67 377 Pfam PF00465 Iron-containing alcohol dehydrogenase 8 368 2.4E-99 T 29-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CDC59_RS22730 e273583508171c2a216eefda934c8a67 377 SUPERFAMILY SSF56796 3 375 5.5E-105 T 29-03-2018 CDC59_RS22730 e273583508171c2a216eefda934c8a67 377 Gene3D G3DSA:3.40.50.1970 8 182 2.9E-42 T 29-03-2018 CDC59_RS22730 e273583508171c2a216eefda934c8a67 377 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 172 200 - T 29-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 CDC59_RS22730 e273583508171c2a216eefda934c8a67 377 Gene3D G3DSA:1.20.1090.10 183 377 4.9E-48 T 29-03-2018 CDC59_RS07195 a98285c432f1244c511f2c86373313da 246 SUPERFAMILY SSF51735 7 232 3.0E-42 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS07195 a98285c432f1244c511f2c86373313da 246 Pfam PF00106 short chain dehydrogenase 8 197 4.4E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS07195 a98285c432f1244c511f2c86373313da 246 Gene3D G3DSA:3.40.50.720 2 185 8.5E-38 T 29-03-2018 CDC59_RS07195 a98285c432f1244c511f2c86373313da 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 2.6E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS07195 a98285c432f1244c511f2c86373313da 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 2.6E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS07195 a98285c432f1244c511f2c86373313da 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 2.6E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS07195 a98285c432f1244c511f2c86373313da 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 2.6E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS07195 a98285c432f1244c511f2c86373313da 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 189 0.0038 T 29-03-2018 CDC59_RS07195 a98285c432f1244c511f2c86373313da 246 Gene3D G3DSA:3.40.50.720 186 238 0.012 T 29-03-2018 CDC59_RS11340 5f5e8b9812c39f6c81f9289a58342997 137 SUPERFAMILY SSF143744 2 133 3.27E-37 T 29-03-2018 CDC59_RS11340 5f5e8b9812c39f6c81f9289a58342997 137 Pfam PF03928 Haem-degrading 7 130 2.8E-30 T 29-03-2018 IPR005624 Haem-degrading CDC59_RS21985 c968576429bfffd1394c86ccfd4ef3bf 798 Gene3D G3DSA:1.25.40.20 463 585 5.8E-18 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CDC59_RS21985 c968576429bfffd1394c86ccfd4ef3bf 798 SUPERFAMILY SSF48403 473 792 3.3E-51 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CDC59_RS21985 c968576429bfffd1394c86ccfd4ef3bf 798 SMART SM00248 673 702 0.16 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CDC59_RS21985 c968576429bfffd1394c86ccfd4ef3bf 798 SMART SM00248 706 736 0.29 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CDC59_RS21985 c968576429bfffd1394c86ccfd4ef3bf 798 SMART SM00248 540 569 14.0 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CDC59_RS21985 c968576429bfffd1394c86ccfd4ef3bf 798 SMART SM00248 505 536 15.0 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CDC59_RS21985 c968576429bfffd1394c86ccfd4ef3bf 798 SMART SM00248 738 767 0.0075 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CDC59_RS21985 c968576429bfffd1394c86ccfd4ef3bf 798 SMART SM00248 606 635 0.0032 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CDC59_RS21985 c968576429bfffd1394c86ccfd4ef3bf 798 SMART SM00248 573 602 1000.0 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CDC59_RS21985 c968576429bfffd1394c86ccfd4ef3bf 798 SMART SM00248 639 668 0.0086 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CDC59_RS21985 c968576429bfffd1394c86ccfd4ef3bf 798 Gene3D G3DSA:1.25.40.20 586 652 4.2E-17 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CDC59_RS21985 c968576429bfffd1394c86ccfd4ef3bf 798 Pfam PF12796 Ankyrin repeats (3 copies) 478 570 5.8E-7 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CDC59_RS21985 c968576429bfffd1394c86ccfd4ef3bf 798 Pfam PF12796 Ankyrin repeats (3 copies) 698 767 4.3E-11 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CDC59_RS21985 c968576429bfffd1394c86ccfd4ef3bf 798 Pfam PF12796 Ankyrin repeats (3 copies) 573 636 1.1E-7 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CDC59_RS21985 c968576429bfffd1394c86ccfd4ef3bf 798 Gene3D G3DSA:1.20.120.660 653 719 1.5E-18 T 29-03-2018 CDC59_RS21985 c968576429bfffd1394c86ccfd4ef3bf 798 Gene3D G3DSA:1.25.40.20 720 795 2.7E-14 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CDC59_RS00705 0ae97532b624c166971327f579bf1e86 256 Gene3D G3DSA:3.40.50.300 4 252 2.4E-55 T 29-03-2018 CDC59_RS00705 0ae97532b624c166971327f579bf1e86 256 SMART SM00382 31 225 7.3E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS00705 0ae97532b624c166971327f579bf1e86 256 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 225 247 2.3E-7 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CDC59_RS00705 0ae97532b624c166971327f579bf1e86 256 SUPERFAMILY SSF52540 5 247 1.22E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS00705 0ae97532b624c166971327f579bf1e86 256 Pfam PF00005 ABC transporter 23 178 6.0E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS20440 2f4e4c73ec0d9cb9aad758309e2cb06d 154 Pfam PF00364 Biotin-requiring enzyme 80 152 1.2E-20 T 29-03-2018 IPR000089 Biotin/lipoyl attachment CDC59_RS20440 2f4e4c73ec0d9cb9aad758309e2cb06d 154 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 83 96 1.3E-10 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CDC59_RS20440 2f4e4c73ec0d9cb9aad758309e2cb06d 154 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 100 114 1.3E-10 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CDC59_RS20440 2f4e4c73ec0d9cb9aad758309e2cb06d 154 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 115 128 1.3E-10 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CDC59_RS20440 2f4e4c73ec0d9cb9aad758309e2cb06d 154 SUPERFAMILY SSF51230 79 152 1.57E-21 T 29-03-2018 IPR011053 Single hybrid motif CDC59_RS20440 2f4e4c73ec0d9cb9aad758309e2cb06d 154 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 110 127 - T 29-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CDC59_RS20440 2f4e4c73ec0d9cb9aad758309e2cb06d 154 Gene3D G3DSA:2.40.50.100 11 106 0.0064 T 29-03-2018 CDC59_RS20440 2f4e4c73ec0d9cb9aad758309e2cb06d 154 Gene3D G3DSA:2.40.50.100 107 154 1.4E-16 T 29-03-2018 CDC59_RS22135 d0cdfe5c371c8a14515d066b636712ac 362 Pfam PF09952 Transcriptional regulator, AbiEi antitoxin, Type IV TA system 211 357 6.8E-5 T 29-03-2018 IPR019238 Transcriptional regulator, AbiEi 2 antitoxin, Type IV TA system CDC59_RS22135 d0cdfe5c371c8a14515d066b636712ac 362 Gene3D G3DSA:1.10.10.10 136 310 2.0E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS02850 aecad15330e7ae3bf6a8dcd7f580d3ef 170 SUPERFAMILY SSF53955 42 163 1.89E-37 T 29-03-2018 IPR023346 Lysozyme-like domain CDC59_RS02850 aecad15330e7ae3bf6a8dcd7f580d3ef 170 Gene3D G3DSA:1.10.530.10 38 167 3.2E-18 T 29-03-2018 CDC59_RS02850 aecad15330e7ae3bf6a8dcd7f580d3ef 170 Pfam PF01464 Transglycosylase SLT domain 47 143 2.9E-16 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 CDC59_RS20400 c63de4040baa9146557a646c1e9e2cae 379 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 169 194 - T 29-03-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 Reactome: R-HSA-71403 CDC59_RS20400 c63de4040baa9146557a646c1e9e2cae 379 SUPERFAMILY SSF52283 1 167 1.36E-46 T 29-03-2018 CDC59_RS20400 c63de4040baa9146557a646c1e9e2cae 379 SMART SM01003 4 136 1.3E-58 T 29-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CDC59_RS20400 c63de4040baa9146557a646c1e9e2cae 379 SUPERFAMILY SSF51735 136 324 3.03E-34 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS20400 c63de4040baa9146557a646c1e9e2cae 379 Gene3D G3DSA:3.40.50.720 193 379 1.1E-38 T 29-03-2018 CDC59_RS20400 c63de4040baa9146557a646c1e9e2cae 379 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 136 2.9E-38 T 29-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CDC59_RS20400 c63de4040baa9146557a646c1e9e2cae 379 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 140 377 4.7E-70 T 29-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CDC59_RS20400 c63de4040baa9146557a646c1e9e2cae 379 Gene3D G3DSA:3.40.50.720 1 192 3.9E-42 T 29-03-2018 CDC59_RS20400 c63de4040baa9146557a646c1e9e2cae 379 SMART SM01002 145 319 1.2E-80 T 29-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CDC59_RS17860 826c36c28b37a2df5e480123eb524380 621 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 38 56 1.1E-5 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CDC59_RS17860 826c36c28b37a2df5e480123eb524380 621 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 17 37 1.1E-5 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CDC59_RS17860 826c36c28b37a2df5e480123eb524380 621 SUPERFAMILY SSF52540 15 181 2.41E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS17860 826c36c28b37a2df5e480123eb524380 621 Gene3D G3DSA:3.40.50.300 7 226 2.3E-28 T 29-03-2018 CDC59_RS17860 826c36c28b37a2df5e480123eb524380 621 Pfam PF07664 Ferrous iron transport protein B C terminus 403 455 1.1E-14 T 29-03-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 CDC59_RS17860 826c36c28b37a2df5e480123eb524380 621 Pfam PF02421 Ferrous iron transport protein B 16 176 3.7E-53 T 29-03-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 CDC59_RS17860 826c36c28b37a2df5e480123eb524380 621 Pfam PF07670 Nucleoside recognition 460 592 4.1E-26 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CDC59_RS17860 826c36c28b37a2df5e480123eb524380 621 Pfam PF07670 Nucleoside recognition 291 385 7.4E-12 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CDC59_RS17860 826c36c28b37a2df5e480123eb524380 621 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 210 588 2.0E-96 T 29-03-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 CDC59_RS12235 1f68b155cbec66513fb87f37c6dea5ea 80 Pfam PF10399 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal 14 42 1.2E-5 T 29-03-2018 IPR019470 Ubiquitinol-cytochrome C reductase, Fe-S subunit, TAT signal GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 CDC59_RS12235 1f68b155cbec66513fb87f37c6dea5ea 80 PIRSF PIRSF036704 11 80 1.2E-14 T 29-03-2018 IPR014177 Putative formate dehydrogenase, TAT signal-containing CDC59_RS12235 1f68b155cbec66513fb87f37c6dea5ea 80 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 21 50 1.9E-5 T 29-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal CDC59_RS12235 1f68b155cbec66513fb87f37c6dea5ea 80 TIGRFAM TIGR02811 formate_TAT: formate dehydrogenase region TAT target 13 78 1.2E-20 T 29-03-2018 IPR014177 Putative formate dehydrogenase, TAT signal-containing CDC59_RS12235 1f68b155cbec66513fb87f37c6dea5ea 80 Gene3D G3DSA:1.20.5.510 15 48 3.3E-5 T 29-03-2018 CDC59_RS20245 349fac4b42c26b6b93239f20fb54332b 477 Gene3D G3DSA:1.10.10.60 307 425 7.9E-10 T 29-03-2018 CDC59_RS20245 349fac4b42c26b6b93239f20fb54332b 477 Gene3D G3DSA:1.10.10.60 426 477 0.0013 T 29-03-2018 CDC59_RS20245 349fac4b42c26b6b93239f20fb54332b 477 Pfam PF12833 Helix-turn-helix domain 395 474 5.6E-16 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CDC59_RS20245 349fac4b42c26b6b93239f20fb54332b 477 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 426 471 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CDC59_RS20245 349fac4b42c26b6b93239f20fb54332b 477 SMART SM00342 389 475 1.2E-19 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CDC59_RS20245 349fac4b42c26b6b93239f20fb54332b 477 SUPERFAMILY SSF48452 54 158 5.42E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS20245 349fac4b42c26b6b93239f20fb54332b 477 Gene3D G3DSA:1.25.40.10 1 174 6.5E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS11685 667e613ac8d4c695d2bfd2557ef70af0 230 SMART SM00382 26 209 4.4E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS11685 667e613ac8d4c695d2bfd2557ef70af0 230 Gene3D G3DSA:3.40.50.300 1 225 8.4E-58 T 29-03-2018 CDC59_RS11685 667e613ac8d4c695d2bfd2557ef70af0 230 Pfam PF00005 ABC transporter 17 159 5.1E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS11685 667e613ac8d4c695d2bfd2557ef70af0 230 TIGRFAM TIGR03410 urea_trans_UrtE: urea ABC transporter, ATP-binding protein UrtE 2 230 1.3E-103 T 29-03-2018 IPR017780 ABC transporter, urea, ATP-binding protein, UrtE CDC59_RS11685 667e613ac8d4c695d2bfd2557ef70af0 230 SUPERFAMILY SSF52540 2 219 2.92E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS04055 2ebce7e28ed12cfdedea4549805c5e8e 327 SUPERFAMILY SSF52768 11 318 9.18E-82 T 29-03-2018 CDC59_RS04055 2ebce7e28ed12cfdedea4549805c5e8e 327 Pfam PF00491 Arginase family 44 315 1.3E-64 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CDC59_RS04055 2ebce7e28ed12cfdedea4549805c5e8e 327 Hamap MF_00737 Formimidoylglutamase [hutG]. 7 317 44.77 T 29-03-2018 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 CDC59_RS04055 2ebce7e28ed12cfdedea4549805c5e8e 327 TIGRFAM TIGR01227 hutG: formimidoylglutamase 12 316 7.7E-101 T 29-03-2018 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 CDC59_RS04055 2ebce7e28ed12cfdedea4549805c5e8e 327 Gene3D G3DSA:3.40.800.10 2 326 7.3E-85 T 29-03-2018 CDC59_RS04055 2ebce7e28ed12cfdedea4549805c5e8e 327 PIRSF PIRSF036979 38 321 7.5E-25 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CDC59_RS17335 8625e5d8e31b5cd091c6b9dcc0efebad 339 TIGRFAM TIGR03944 dehyd_SbnB_fam: 2,3-diaminopropionate biosynthesis protein SbnB 9 338 3.7E-128 T 29-03-2018 IPR023866 2,3-diaminopropionate biosynthesis protein SbnB CDC59_RS17335 8625e5d8e31b5cd091c6b9dcc0efebad 339 Gene3D G3DSA:3.30.1780.10 7 150 8.6E-32 T 29-03-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 CDC59_RS17335 8625e5d8e31b5cd091c6b9dcc0efebad 339 SUPERFAMILY SSF51735 9 338 2.22E-81 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS17335 8625e5d8e31b5cd091c6b9dcc0efebad 339 PIRSF PIRSF001439 3 339 8.0E-100 T 29-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CDC59_RS17335 8625e5d8e31b5cd091c6b9dcc0efebad 339 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 29 329 3.1E-62 T 29-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CDC59_RS17335 8625e5d8e31b5cd091c6b9dcc0efebad 339 Gene3D G3DSA:3.40.50.720 151 311 2.9E-29 T 29-03-2018 CDC59_RS19640 771e8614c9bfe6c31d37b0a4af0462d4 496 Pfam PF05943 Type VI secretion protein, EvpB/VC_A0108, tail sheath 69 491 7.6E-195 T 29-03-2018 IPR010269 Type VI secretion protein, EvpB/VC_A0108, tail sheath CDC59_RS19640 771e8614c9bfe6c31d37b0a4af0462d4 496 TIGRFAM TIGR03355 VI_chp_2: type VI secretion protein, EvpB/VC_A0108 family 20 491 2.3E-221 T 29-03-2018 IPR010269 Type VI secretion protein, EvpB/VC_A0108, tail sheath CDC59_RS12260 9e9e9a35d31a0e8169229300b47d2785 362 ProSitePatterns PS01215 Mrp family signature. 203 219 - T 29-03-2018 IPR000808 Mrp, conserved site GO:0005524 CDC59_RS12260 9e9e9a35d31a0e8169229300b47d2785 362 Gene3D G3DSA:3.30.300.130 2 87 8.1E-15 T 29-03-2018 IPR034904 Fe-S cluster assembly domain CDC59_RS12260 9e9e9a35d31a0e8169229300b47d2785 362 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 96 339 3.1E-104 T 29-03-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 CDC59_RS12260 9e9e9a35d31a0e8169229300b47d2785 362 Gene3D G3DSA:3.40.50.300 88 318 2.7E-67 T 29-03-2018 CDC59_RS12260 9e9e9a35d31a0e8169229300b47d2785 362 Hamap MF_02040 Iron-sulfur cluster carrier protein. 92 340 37.854 T 29-03-2018 IPR019591 Mrp/NBP35 ATP-binding protein CDC59_RS12260 9e9e9a35d31a0e8169229300b47d2785 362 SUPERFAMILY SSF117916 3 84 1.73E-19 T 29-03-2018 IPR034904 Fe-S cluster assembly domain CDC59_RS12260 9e9e9a35d31a0e8169229300b47d2785 362 SUPERFAMILY SSF52540 89 324 3.62E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS12260 9e9e9a35d31a0e8169229300b47d2785 362 Pfam PF01883 Iron-sulfur cluster assembly protein 6 78 3.8E-24 T 29-03-2018 IPR002744 MIP18 family-like CDC59_RS12365 9e199715dc281f40137d4518e80ed858 626 Gene3D G3DSA:2.40.170.20 166 620 4.9E-61 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CDC59_RS12365 9e199715dc281f40137d4518e80ed858 626 Pfam PF00593 TonB dependent receptor 206 619 1.1E-43 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CDC59_RS12365 9e199715dc281f40137d4518e80ed858 626 Pfam PF07715 TonB-dependent Receptor Plug Domain 57 157 1.3E-25 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CDC59_RS12365 9e199715dc281f40137d4518e80ed858 626 SUPERFAMILY SSF56935 41 619 3.56E-103 T 29-03-2018 CDC59_RS12365 9e199715dc281f40137d4518e80ed858 626 Gene3D G3DSA:2.170.130.10 33 164 3.4E-30 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CDC59_RS19810 df4db0d388d0d8ae4b0ff590c0dcc121 395 Gene3D G3DSA:3.90.1150.10 283 394 5.3E-30 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS19810 df4db0d388d0d8ae4b0ff590c0dcc121 395 Gene3D G3DSA:3.40.640.10 52 282 4.0E-53 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDC59_RS19810 df4db0d388d0d8ae4b0ff590c0dcc121 395 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 242 255 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CDC59_RS19810 df4db0d388d0d8ae4b0ff590c0dcc121 395 SUPERFAMILY SSF53383 23 393 2.1E-103 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS19810 df4db0d388d0d8ae4b0ff590c0dcc121 395 Pfam PF00155 Aminotransferase class I and II 51 389 3.0E-52 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CDC59_RS20900 61068ec8ec2f99a7c05529193498ce84 609 ProSitePatterns PS00211 ABC transporters family signature. 488 502 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS20900 61068ec8ec2f99a7c05529193498ce84 609 SUPERFAMILY SSF52540 343 586 5.98E-84 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS20900 61068ec8ec2f99a7c05529193498ce84 609 SUPERFAMILY SSF90123 19 337 2.35E-32 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CDC59_RS20900 61068ec8ec2f99a7c05529193498ce84 609 Pfam PF00664 ABC transporter transmembrane region 71 247 1.9E-8 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CDC59_RS20900 61068ec8ec2f99a7c05529193498ce84 609 Pfam PF00005 ABC transporter 367 516 1.1E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS20900 61068ec8ec2f99a7c05529193498ce84 609 Gene3D G3DSA:1.20.1560.10 1 338 1.2E-19 T 29-03-2018 CDC59_RS20900 61068ec8ec2f99a7c05529193498ce84 609 Gene3D G3DSA:3.40.50.300 339 591 7.1E-73 T 29-03-2018 CDC59_RS20900 61068ec8ec2f99a7c05529193498ce84 609 SMART SM00382 376 562 1.7E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS06260 07375b565dbfb10a93e50c8bef01bf21 156 SUPERFAMILY SSF75217 1 154 1.47E-49 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases CDC59_RS06260 07375b565dbfb10a93e50c8bef01bf21 156 Gene3D G3DSA:3.40.1280.10 1 155 1.7E-52 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CDC59_RS06260 07375b565dbfb10a93e50c8bef01bf21 156 TIGRFAM TIGR00246 tRNA_RlmH_YbeA: rRNA large subunit m3Psi methyltransferase RlmH 2 155 1.3E-44 T 29-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CDC59_RS06260 07375b565dbfb10a93e50c8bef01bf21 156 Pfam PF02590 Predicted SPOUT methyltransferase 1 154 5.2E-50 T 29-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CDC59_RS06260 07375b565dbfb10a93e50c8bef01bf21 156 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 155 28.748 T 29-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CDC59_RS06260 07375b565dbfb10a93e50c8bef01bf21 156 PIRSF PIRSF004505 1 155 1.1E-46 T 29-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CDC59_RS17145 3136d03395b101bf18f51c4ea78bf12d 142 SUPERFAMILY SSF101116 10 128 2.75E-35 T 29-03-2018 IPR003713 Flagellar protein FliS GO:0044780 CDC59_RS17145 3136d03395b101bf18f51c4ea78bf12d 142 Gene3D G3DSA:1.20.120.340 1 129 1.0E-36 T 29-03-2018 CDC59_RS17145 3136d03395b101bf18f51c4ea78bf12d 142 TIGRFAM TIGR00208 fliS: flagellar protein FliS 4 126 1.1E-29 T 29-03-2018 IPR003713 Flagellar protein FliS GO:0044780 CDC59_RS17145 3136d03395b101bf18f51c4ea78bf12d 142 PIRSF PIRSF039090 2 133 7.2E-38 T 29-03-2018 IPR003713 Flagellar protein FliS GO:0044780 CDC59_RS17145 3136d03395b101bf18f51c4ea78bf12d 142 Pfam PF02561 Flagellar protein FliS 10 126 2.4E-34 T 29-03-2018 IPR003713 Flagellar protein FliS GO:0044780 CDC59_RS02805 eb778cdc4bd202d1ac2ad128ff91d387 213 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 22 206 7.0E-72 T 29-03-2018 IPR004507 Flavin prenyltransferase UbiX/Pad1 CDC59_RS02805 eb778cdc4bd202d1ac2ad128ff91d387 213 Gene3D G3DSA:3.40.50.1950 21 213 1.4E-53 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CDC59_RS02805 eb778cdc4bd202d1ac2ad128ff91d387 213 Pfam PF02441 Flavoprotein 22 187 7.2E-27 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CDC59_RS02805 eb778cdc4bd202d1ac2ad128ff91d387 213 SUPERFAMILY SSF52507 21 208 2.49E-62 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CDC59_RS02805 eb778cdc4bd202d1ac2ad128ff91d387 213 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 21 208 37.464 T 29-03-2018 IPR004507 Flavin prenyltransferase UbiX/Pad1 CDC59_RS02895 56c7366a21c0941d6707da83197d6907 223 Gene3D G3DSA:2.40.320.10 1 222 5.0E-37 T 29-03-2018 CDC59_RS02895 56c7366a21c0941d6707da83197d6907 223 Pfam PF01928 CYTH domain 3 212 4.3E-41 T 29-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 CDC59_RS02895 56c7366a21c0941d6707da83197d6907 223 SMART SM01118 2 218 2.8E-33 T 29-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 CDC59_RS02895 56c7366a21c0941d6707da83197d6907 223 SUPERFAMILY SSF55154 1 217 5.72E-40 T 29-03-2018 IPR033469 CYTH-like domain Reactome: R-HSA-196819 CDC59_RS17715 ad070a2b0c59fdcda62d37698c99929e 627 Pfam PF00501 AMP-binding enzyme 53 459 1.5E-59 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CDC59_RS17715 ad070a2b0c59fdcda62d37698c99929e 627 Gene3D G3DSA:3.40.50.980 226 391 6.5E-28 T 29-03-2018 CDC59_RS17715 ad070a2b0c59fdcda62d37698c99929e 627 Gene3D G3DSA:3.40.50.980 45 225 5.7E-26 T 29-03-2018 CDC59_RS17715 ad070a2b0c59fdcda62d37698c99929e 627 SUPERFAMILY SSF56801 40 608 9.94E-82 T 29-03-2018 CDC59_RS17715 ad070a2b0c59fdcda62d37698c99929e 627 Gene3D G3DSA:2.30.38.10 392 470 7.1E-11 T 29-03-2018 CDC59_RS06010 cfc2f29901ffd7603581b5da85d2088b 391 SUPERFAMILY SSF53822 29 382 6.54E-74 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CDC59_RS06010 cfc2f29901ffd7603581b5da85d2088b 391 Gene3D G3DSA:3.40.50.2300 30 153 4.9E-16 T 29-03-2018 CDC59_RS06010 cfc2f29901ffd7603581b5da85d2088b 391 Gene3D G3DSA:3.40.50.2300 154 330 2.9E-28 T 29-03-2018 CDC59_RS06010 cfc2f29901ffd7603581b5da85d2088b 391 Pfam PF13458 Periplasmic binding protein 29 373 2.7E-56 T 29-03-2018 IPR028081 Leucine-binding protein domain CDC59_RS12150 4bd044c7ca2cf3641602d3619fce5d99 334 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 22 228 4.1E-75 T 29-03-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CDC59_RS12150 4bd044c7ca2cf3641602d3619fce5d99 334 SUPERFAMILY SSF54782 236 326 1.44E-21 T 29-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CDC59_RS12150 4bd044c7ca2cf3641602d3619fce5d99 334 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 247 263 - T 29-03-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CDC59_RS12150 4bd044c7ca2cf3641602d3619fce5d99 334 Gene3D G3DSA:3.30.160.40 237 324 9.2E-24 T 29-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CDC59_RS12150 4bd044c7ca2cf3641602d3619fce5d99 334 SUPERFAMILY SSF53850 21 235 1.3E-80 T 29-03-2018 CDC59_RS12150 4bd044c7ca2cf3641602d3619fce5d99 334 Gene3D G3DSA:3.40.190.10 123 215 1.0E-35 T 29-03-2018 CDC59_RS12150 4bd044c7ca2cf3641602d3619fce5d99 334 Gene3D G3DSA:3.40.190.10 14 122 1.8E-44 T 29-03-2018 CDC59_RS12150 4bd044c7ca2cf3641602d3619fce5d99 334 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 22 316 2.8E-103 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CDC59_RS12150 4bd044c7ca2cf3641602d3619fce5d99 334 PRINTS PR00151 Porphobilinogen deaminase signature 159 176 1.2E-46 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CDC59_RS12150 4bd044c7ca2cf3641602d3619fce5d99 334 PRINTS PR00151 Porphobilinogen deaminase signature 246 263 1.2E-46 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CDC59_RS12150 4bd044c7ca2cf3641602d3619fce5d99 334 PRINTS PR00151 Porphobilinogen deaminase signature 92 111 1.2E-46 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CDC59_RS12150 4bd044c7ca2cf3641602d3619fce5d99 334 PRINTS PR00151 Porphobilinogen deaminase signature 140 157 1.2E-46 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CDC59_RS12150 4bd044c7ca2cf3641602d3619fce5d99 334 PRINTS PR00151 Porphobilinogen deaminase signature 61 81 1.2E-46 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CDC59_RS12150 4bd044c7ca2cf3641602d3619fce5d99 334 PIRSF PIRSF001438 2 330 2.4E-116 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CDC59_RS12150 4bd044c7ca2cf3641602d3619fce5d99 334 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 242 315 1.3E-16 T 29-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CDC59_RS12150 4bd044c7ca2cf3641602d3619fce5d99 334 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 21 317 37.575 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CDC59_RS14545 adabdb8c5b26439640f905bf8c54ca57 151 SUPERFAMILY SSF53062 1 127 1.09E-29 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CDC59_RS14545 adabdb8c5b26439640f905bf8c54ca57 151 Gene3D G3DSA:3.40.50.510 1 142 5.7E-37 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CDC59_RS14545 adabdb8c5b26439640f905bf8c54ca57 151 Pfam PF03610 PTS system fructose IIA component 3 106 4.3E-18 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CDC59_RS19315 470466e9a27dfdffaa431fb6f93d52df 1029 SUPERFAMILY SSF82714 694 781 3.66E-10 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS19315 470466e9a27dfdffaa431fb6f93d52df 1029 Gene3D G3DSA:1.20.1640.10 266 490 1.2E-41 T 29-03-2018 CDC59_RS19315 470466e9a27dfdffaa431fb6f93d52df 1029 Gene3D G3DSA:1.20.1640.10 785 1001 4.7E-41 T 29-03-2018 CDC59_RS19315 470466e9a27dfdffaa431fb6f93d52df 1029 Gene3D G3DSA:3.30.2090.10 693 783 4.4E-14 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS19315 470466e9a27dfdffaa431fb6f93d52df 1029 Gene3D G3DSA:3.30.70.1430 547 648 7.7E-20 T 29-03-2018 CDC59_RS19315 470466e9a27dfdffaa431fb6f93d52df 1029 PRINTS PR00702 Acriflavin resistance protein family signature 383 407 8.5E-56 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS19315 470466e9a27dfdffaa431fb6f93d52df 1029 PRINTS PR00702 Acriflavin resistance protein family signature 461 484 8.5E-56 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS19315 470466e9a27dfdffaa431fb6f93d52df 1029 PRINTS PR00702 Acriflavin resistance protein family signature 436 459 8.5E-56 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS19315 470466e9a27dfdffaa431fb6f93d52df 1029 PRINTS PR00702 Acriflavin resistance protein family signature 355 376 8.5E-56 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS19315 470466e9a27dfdffaa431fb6f93d52df 1029 PRINTS PR00702 Acriflavin resistance protein family signature 531 548 8.5E-56 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS19315 470466e9a27dfdffaa431fb6f93d52df 1029 PRINTS PR00702 Acriflavin resistance protein family signature 328 351 8.5E-56 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS19315 470466e9a27dfdffaa431fb6f93d52df 1029 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 8.5E-56 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS19315 470466e9a27dfdffaa431fb6f93d52df 1029 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 8.5E-56 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS19315 470466e9a27dfdffaa431fb6f93d52df 1029 SUPERFAMILY SSF82714 182 264 2.35E-12 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS19315 470466e9a27dfdffaa431fb6f93d52df 1029 SUPERFAMILY SSF82693 136 181 2.51E-15 T 29-03-2018 CDC59_RS19315 470466e9a27dfdffaa431fb6f93d52df 1029 SUPERFAMILY SSF82693 267 311 2.51E-15 T 29-03-2018 CDC59_RS19315 470466e9a27dfdffaa431fb6f93d52df 1029 Gene3D G3DSA:3.30.70.1430 40 142 4.2E-29 T 29-03-2018 CDC59_RS19315 470466e9a27dfdffaa431fb6f93d52df 1029 SUPERFAMILY SSF82693 40 132 2.09E-24 T 29-03-2018 CDC59_RS19315 470466e9a27dfdffaa431fb6f93d52df 1029 SUPERFAMILY SSF82866 289 488 9.16E-46 T 29-03-2018 CDC59_RS19315 470466e9a27dfdffaa431fb6f93d52df 1029 Gene3D G3DSA:3.30.2090.10 180 265 8.6E-15 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS19315 470466e9a27dfdffaa431fb6f93d52df 1029 Pfam PF00873 AcrB/AcrD/AcrF family 4 1001 2.6E-238 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS19315 470466e9a27dfdffaa431fb6f93d52df 1029 SUPERFAMILY SSF82866 781 1003 9.02E-47 T 29-03-2018 CDC59_RS19315 470466e9a27dfdffaa431fb6f93d52df 1029 SUPERFAMILY SSF82693 544 644 2.77E-13 T 29-03-2018 CDC59_RS19535 fa5e8e2532b7dc28cc433330aac65d09 186 SMART SM00900 98 179 5.9E-10 T 29-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 CDC59_RS19535 fa5e8e2532b7dc28cc433330aac65d09 186 Pfam PF04205 FMN-binding domain 103 175 8.8E-9 T 29-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 CDC59_RS19535 fa5e8e2532b7dc28cc433330aac65d09 186 Gene3D G3DSA:3.40.630.30 20 183 3.2E-4 T 29-03-2018 CDC59_RS04530 570c8edf8fd5dd1fe84f3450a446bf0c 484 Pfam PF02321 Outer membrane efflux protein 251 440 1.8E-28 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CDC59_RS04530 570c8edf8fd5dd1fe84f3450a446bf0c 484 Pfam PF02321 Outer membrane efflux protein 42 227 2.7E-25 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CDC59_RS04530 570c8edf8fd5dd1fe84f3450a446bf0c 484 SUPERFAMILY SSF56954 40 456 9.29E-87 T 29-03-2018 CDC59_RS04530 570c8edf8fd5dd1fe84f3450a446bf0c 484 Gene3D G3DSA:1.20.1600.10 25 451 4.7E-72 T 29-03-2018 CDC59_RS04530 570c8edf8fd5dd1fe84f3450a446bf0c 484 TIGRFAM TIGR01844 type_I_sec_TolC: type I secretion outer membrane protein, TolC family 39 455 3.2E-100 T 29-03-2018 IPR010130 Type I secretion outer membrane protein, TolC GO:0006810|GO:0019867 CDC59_RS11945 9e236e6b4910bdbae749359337b89301 192 Pfam PF06041 Bacterial protein of unknown function (DUF924) 10 189 7.2E-61 T 29-03-2018 IPR010323 Protein of unknown function DUF924 CDC59_RS11945 9e236e6b4910bdbae749359337b89301 192 SUPERFAMILY SSF48452 4 188 2.88E-62 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS11945 9e236e6b4910bdbae749359337b89301 192 Gene3D G3DSA:1.20.58.320 4 86 9.3E-26 T 29-03-2018 CDC59_RS11945 9e236e6b4910bdbae749359337b89301 192 Gene3D G3DSA:1.25.40.10 87 192 2.8E-33 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS15710 6065f91c11cd785164381a2de504f372 277 Pfam PF05853 beta-keto acid cleavage enzyme 5 274 2.0E-67 T 29-03-2018 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00310+2.3.1.247|KEGG: 00600+2.3.1.24 CDC59_RS15710 6065f91c11cd785164381a2de504f372 277 Gene3D G3DSA:3.20.20.70 2 276 1.0E-73 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS15710 6065f91c11cd785164381a2de504f372 277 SUPERFAMILY SSF51395 26 154 6.23E-5 T 29-03-2018 CDC59_RS17225 18b6c366785798d0fa0c88853779ec39 507 Pfam PF00990 Diguanylate cyclase, GGDEF domain 324 485 8.6E-46 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS17225 18b6c366785798d0fa0c88853779ec39 507 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 322 486 1.2E-49 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS17225 18b6c366785798d0fa0c88853779ec39 507 Gene3D G3DSA:3.30.450.20 57 169 1.9E-12 T 29-03-2018 CDC59_RS17225 18b6c366785798d0fa0c88853779ec39 507 SMART SM00267 307 489 8.4E-59 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS17225 18b6c366785798d0fa0c88853779ec39 507 SUPERFAMILY SSF55073 329 487 1.86E-44 T 29-03-2018 IPR029787 Nucleotide cyclase CDC59_RS17225 18b6c366785798d0fa0c88853779ec39 507 Gene3D G3DSA:3.30.70.270 317 497 2.9E-51 T 29-03-2018 CDC59_RS17225 18b6c366785798d0fa0c88853779ec39 507 Gene3D G3DSA:3.30.450.20 170 285 3.7E-10 T 29-03-2018 CDC59_RS17225 18b6c366785798d0fa0c88853779ec39 507 Pfam PF02743 Cache domain 99 270 2.6E-15 T 29-03-2018 IPR033479 Double Cache domain 1 CDC59_RS03050 2b1bbe99325a110c45e01383948be917 329 Gene3D G3DSA:3.40.50.2300 166 327 2.4E-43 T 29-03-2018 CDC59_RS03050 2b1bbe99325a110c45e01383948be917 329 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 48 1.5E-13 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDC59_RS03050 2b1bbe99325a110c45e01383948be917 329 Pfam PF13377 Periplasmic binding protein-like domain 167 324 2.5E-32 T 29-03-2018 CDC59_RS03050 2b1bbe99325a110c45e01383948be917 329 SUPERFAMILY SSF53822 60 317 2.36E-63 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CDC59_RS03050 2b1bbe99325a110c45e01383948be917 329 SUPERFAMILY SSF47413 2 57 1.13E-13 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDC59_RS03050 2b1bbe99325a110c45e01383948be917 329 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 29-03-2018 CDC59_RS03050 2b1bbe99325a110c45e01383948be917 329 Gene3D G3DSA:1.10.260.40 3 57 5.4E-19 T 29-03-2018 CDC59_RS03050 2b1bbe99325a110c45e01383948be917 329 SMART SM00354 2 71 5.5E-26 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDC59_RS03050 2b1bbe99325a110c45e01383948be917 329 Gene3D G3DSA:3.40.50.2300 58 165 1.3E-31 T 29-03-2018 CDC59_RS22625 c59b4815cf0d014959e7cf9b83f2729c 171 Gene3D G3DSA:3.40.30.10 18 171 4.4E-7 T 29-03-2018 CDC59_RS22625 c59b4815cf0d014959e7cf9b83f2729c 171 SUPERFAMILY SSF52833 48 169 2.07E-7 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS00895 dea50b5afd58a47b2afe0c3e84a9fa0b 297 Gene3D G3DSA:3.40.190.10 194 259 7.3E-5 T 29-03-2018 CDC59_RS00895 dea50b5afd58a47b2afe0c3e84a9fa0b 297 SUPERFAMILY SSF46785 5 118 2.45E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS00895 dea50b5afd58a47b2afe0c3e84a9fa0b 297 Gene3D G3DSA:3.40.190.10 93 193 2.4E-15 T 29-03-2018 CDC59_RS00895 dea50b5afd58a47b2afe0c3e84a9fa0b 297 SUPERFAMILY SSF53850 92 294 4.89E-26 T 29-03-2018 CDC59_RS00895 dea50b5afd58a47b2afe0c3e84a9fa0b 297 Pfam PF03466 LysR substrate binding domain 96 294 5.9E-24 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS00895 dea50b5afd58a47b2afe0c3e84a9fa0b 297 Gene3D G3DSA:1.10.10.10 1 92 1.4E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS00895 dea50b5afd58a47b2afe0c3e84a9fa0b 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 13 62 4.4E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS08145 ac345b313703c308d148676956b8a8f3 383 PIRSF PIRSF006004 3 365 4.1E-147 T 29-03-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CDC59_RS08145 ac345b313703c308d148676956b8a8f3 383 Pfam PF04055 Radical SAM superfamily 108 284 1.2E-16 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CDC59_RS08145 ac345b313703c308d148676956b8a8f3 383 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 4 357 1.6E-135 T 29-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CDC59_RS08145 ac345b313703c308d148676956b8a8f3 383 Gene3D G3DSA:3.20.20.70 16 371 2.4E-40 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS08145 ac345b313703c308d148676956b8a8f3 383 SUPERFAMILY SSF102114 103 310 6.8E-12 T 29-03-2018 CDC59_RS08145 ac345b313703c308d148676956b8a8f3 383 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 4 353 73.226 T 29-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CDC59_RS04595 6dca63c92f8e719b719baff132a6b3c1 198 PIRSF PIRSF029669 1 198 1.9E-85 T 29-03-2018 IPR016932 Uncharacterised conserved protein UCP029669 CDC59_RS04595 6dca63c92f8e719b719baff132a6b3c1 198 SUPERFAMILY SSF110849 3 197 5.75E-67 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CDC59_RS04595 6dca63c92f8e719b719baff132a6b3c1 198 Gene3D G3DSA:3.90.1530.10 1 129 3.4E-39 T 29-03-2018 CDC59_RS04595 6dca63c92f8e719b719baff132a6b3c1 198 Gene3D G3DSA:1.10.8.10 130 189 1.9E-21 T 29-03-2018 CDC59_RS04595 6dca63c92f8e719b719baff132a6b3c1 198 Pfam PF08857 Putative ParB-like nuclease 7 162 4.2E-53 T 29-03-2018 IPR014956 Putative ParB-like nuclease CDC59_RS14755 3208fddb581ee1e2ebd6d07c5a6c9363 273 Gene3D G3DSA:3.30.70.1070 117 181 0.0055 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 CDC59_RS14755 3208fddb581ee1e2ebd6d07c5a6c9363 273 Gene3D G3DSA:3.30.70.1070 182 258 3.6E-5 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 CDC59_RS14755 3208fddb581ee1e2ebd6d07c5a6c9363 273 SUPERFAMILY SSF110997 145 216 1.44E-8 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 CDC59_RS16750 0ecb155a9dc312c4da26e338bb7beaed 424 SUPERFAMILY SSF53448 47 328 3.46E-62 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDC59_RS16750 0ecb155a9dc312c4da26e338bb7beaed 424 Pfam PF00535 Glycosyl transferase family 2 59 227 3.5E-30 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CDC59_RS16750 0ecb155a9dc312c4da26e338bb7beaed 424 Gene3D G3DSA:3.90.550.10 44 304 3.2E-54 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDC59_RS16750 0ecb155a9dc312c4da26e338bb7beaed 424 TIGRFAM TIGR03937 PgaC_IcaA: poly-beta-1,6 N-acetyl-D-glucosamine synthase 12 417 6.6E-178 T 29-03-2018 IPR023853 Poly-beta-1,6 N-acetyl-D-glucosamine synthase PgaC/IcaA GO:0008375|GO:0042710 CDC59_RS01730 a6bbceaaee5058592d4bff821e399f96 132 Pfam PF07963 Prokaryotic N-terminal methylation motif 9 32 2.6E-8 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS01730 a6bbceaaee5058592d4bff821e399f96 132 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 11 31 - T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS01730 a6bbceaaee5058592d4bff821e399f96 132 Gene3D G3DSA:3.30.1300.30 37 131 4.2E-20 T 29-03-2018 CDC59_RS01730 a6bbceaaee5058592d4bff821e399f96 132 Pfam PF02501 Type II secretion system (T2SS), protein I 46 124 3.7E-22 T 29-03-2018 IPR003413 Type II secretion system protein I domain GO:0008565|GO:0015627|GO:0015628 CDC59_RS01730 a6bbceaaee5058592d4bff821e399f96 132 SUPERFAMILY SSF54523 45 124 6.8E-19 T 29-03-2018 CDC59_RS01730 a6bbceaaee5058592d4bff821e399f96 132 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 10 32 3.1E-8 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS01730 a6bbceaaee5058592d4bff821e399f96 132 TIGRFAM TIGR01707 gspI: type II secretion system protein I 12 110 4.8E-23 T 29-03-2018 IPR010052 Type II secretion system protein I GO:0008565|GO:0015627|GO:0015628 CDC59_RS00625 eb7f87424dc5eab70cdc82071b3172b9 92 Gene3D G3DSA:4.10.520.10 1 92 2.6E-30 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CDC59_RS00625 eb7f87424dc5eab70cdc82071b3172b9 92 SUPERFAMILY SSF47729 1 91 1.19E-28 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CDC59_RS00625 eb7f87424dc5eab70cdc82071b3172b9 92 PRINTS PR01727 Prokaryotic integration host factor signature 75 89 8.5E-15 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CDC59_RS00625 eb7f87424dc5eab70cdc82071b3172b9 92 PRINTS PR01727 Prokaryotic integration host factor signature 59 72 8.5E-15 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CDC59_RS00625 eb7f87424dc5eab70cdc82071b3172b9 92 PRINTS PR01727 Prokaryotic integration host factor signature 41 56 8.5E-15 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CDC59_RS00625 eb7f87424dc5eab70cdc82071b3172b9 92 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 47 66 - T 29-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 CDC59_RS00625 eb7f87424dc5eab70cdc82071b3172b9 92 Pfam PF00216 Bacterial DNA-binding protein 1 91 2.5E-29 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CDC59_RS00625 eb7f87424dc5eab70cdc82071b3172b9 92 SMART SM00411 1 91 2.5E-34 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CDC59_RS01575 e6fa67dece8ffe3897a41449b5a3bfaf 159 Gene3D G3DSA:1.10.10.10 1 159 8.5E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS01575 e6fa67dece8ffe3897a41449b5a3bfaf 159 Pfam PF01047 MarR family 52 110 3.6E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS01575 e6fa67dece8ffe3897a41449b5a3bfaf 159 PRINTS PR00598 Bacterial regulatory protein MarR family signature 105 121 1.1E-15 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS01575 e6fa67dece8ffe3897a41449b5a3bfaf 159 PRINTS PR00598 Bacterial regulatory protein MarR family signature 135 155 1.1E-15 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS01575 e6fa67dece8ffe3897a41449b5a3bfaf 159 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 101 1.1E-15 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS01575 e6fa67dece8ffe3897a41449b5a3bfaf 159 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 85 1.1E-15 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS01575 e6fa67dece8ffe3897a41449b5a3bfaf 159 SMART SM00347 45 145 2.0E-24 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS01575 e6fa67dece8ffe3897a41449b5a3bfaf 159 SUPERFAMILY SSF46785 19 158 5.0E-34 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS14635 ffd6c0281eb166e2ae0b73bd13e424ed 108 SUPERFAMILY SSF52833 5 102 3.24E-26 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS14635 ffd6c0281eb166e2ae0b73bd13e424ed 108 Gene3D G3DSA:3.40.30.10 4 108 5.2E-26 T 29-03-2018 CDC59_RS08575 95a08024ec8568cd72a014e0dffcc4da 314 SUPERFAMILY SSF55120 17 255 2.07E-81 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDC59_RS08575 95a08024ec8568cd72a014e0dffcc4da 314 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 18 229 5.5E-78 T 29-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDC59_RS08575 95a08024ec8568cd72a014e0dffcc4da 314 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 39 190 1.6E-55 T 29-03-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 CDC59_RS08575 95a08024ec8568cd72a014e0dffcc4da 314 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 191 248 8.2E-17 T 29-03-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 CDC59_RS08575 95a08024ec8568cd72a014e0dffcc4da 314 Pfam PF09157 Pseudouridine synthase II TruB, C-terminal 252 312 6.9E-16 T 29-03-2018 IPR015240 tRNA pseudouridine synthase II, TruB, subfamily 1, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDC59_RS08575 95a08024ec8568cd72a014e0dffcc4da 314 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 17 312 19.299 T 29-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDC59_RS08575 95a08024ec8568cd72a014e0dffcc4da 314 Gene3D G3DSA:2.30.130.10 250 313 4.2E-16 T 29-03-2018 IPR002478 PUA domain GO:0003723 CDC59_RS08575 95a08024ec8568cd72a014e0dffcc4da 314 Gene3D G3DSA:3.30.2350.10 16 240 6.9E-82 T 29-03-2018 CDC59_RS08575 95a08024ec8568cd72a014e0dffcc4da 314 SUPERFAMILY SSF88697 251 313 3.98E-5 T 29-03-2018 IPR015947 PUA-like domain CDC59_RS15515 8e9bdfe7067136bc2faac888c1a478e0 152 ProSitePatterns PS00519 AsnC-type HTH domain signature. 21 47 - T 29-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site CDC59_RS15515 8e9bdfe7067136bc2faac888c1a478e0 152 Gene3D G3DSA:1.10.10.10 3 52 3.9E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS15515 8e9bdfe7067136bc2faac888c1a478e0 152 SUPERFAMILY SSF46785 2 62 4.23E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS15515 8e9bdfe7067136bc2faac888c1a478e0 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 2.9E-14 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CDC59_RS15515 8e9bdfe7067136bc2faac888c1a478e0 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 2.9E-14 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CDC59_RS15515 8e9bdfe7067136bc2faac888c1a478e0 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 2.9E-14 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CDC59_RS15515 8e9bdfe7067136bc2faac888c1a478e0 152 Gene3D G3DSA:3.30.70.920 53 140 1.8E-14 T 29-03-2018 CDC59_RS15515 8e9bdfe7067136bc2faac888c1a478e0 152 Pfam PF01037 Lrp/AsnC ligand binding domain 69 136 3.8E-11 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CDC59_RS15515 8e9bdfe7067136bc2faac888c1a478e0 152 Pfam PF13404 AsnC-type helix-turn-helix domain 3 44 4.0E-14 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CDC59_RS15515 8e9bdfe7067136bc2faac888c1a478e0 152 SMART SM00344 3 109 7.0E-31 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CDC59_RS15515 8e9bdfe7067136bc2faac888c1a478e0 152 SUPERFAMILY SSF54909 64 137 4.96E-13 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CDC59_RS17735 78ef4d75f95becbcca1c65dd3e3a6900 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 9.3E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS17735 78ef4d75f95becbcca1c65dd3e3a6900 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 9.3E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS17735 78ef4d75f95becbcca1c65dd3e3a6900 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 9.3E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS17735 78ef4d75f95becbcca1c65dd3e3a6900 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 67 78 9.3E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS17735 78ef4d75f95becbcca1c65dd3e3a6900 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 104 120 9.3E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS17735 78ef4d75f95becbcca1c65dd3e3a6900 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 150 250 1.0E-13 T 29-03-2018 CDC59_RS17735 78ef4d75f95becbcca1c65dd3e3a6900 255 Gene3D G3DSA:3.40.50.720 1 252 7.9E-46 T 29-03-2018 CDC59_RS17735 78ef4d75f95becbcca1c65dd3e3a6900 255 SUPERFAMILY SSF51735 5 252 2.91E-48 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS17735 78ef4d75f95becbcca1c65dd3e3a6900 255 Pfam PF00106 short chain dehydrogenase 6 121 6.9E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS19230 5d1190e3830303341ece85f3e46a80a6 298 Gene3D G3DSA:1.10.1040.10 164 293 9.6E-34 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CDC59_RS19230 5d1190e3830303341ece85f3e46a80a6 298 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 164 291 7.4E-36 T 29-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CDC59_RS19230 5d1190e3830303341ece85f3e46a80a6 298 SUPERFAMILY SSF48179 163 292 1.59E-40 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CDC59_RS19230 5d1190e3830303341ece85f3e46a80a6 298 TIGRFAM TIGR01692 HIBADH: 3-hydroxyisobutyrate dehydrogenase 5 292 1.1E-143 T 29-03-2018 IPR011548 3-hydroxyisobutyrate dehydrogenase GO:0008442|GO:0051287|GO:0055114 KEGG: 00280+1.1.1.31|Reactome: R-HSA-70895 CDC59_RS19230 5d1190e3830303341ece85f3e46a80a6 298 PIRSF PIRSF000103 1 298 9.9E-84 T 29-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CDC59_RS19230 5d1190e3830303341ece85f3e46a80a6 298 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 161 2.4E-50 T 29-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CDC59_RS19230 5d1190e3830303341ece85f3e46a80a6 298 SUPERFAMILY SSF51735 1 162 3.4E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS19230 5d1190e3830303341ece85f3e46a80a6 298 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 5 18 - T 29-03-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 CDC59_RS19230 5d1190e3830303341ece85f3e46a80a6 298 Gene3D G3DSA:3.40.50.720 1 163 1.0E-33 T 29-03-2018 CDC59_RS22295 780ff4a052f4d40f7281fc2dc6b9f760 322 Gene3D G3DSA:1.10.3470.10 13 315 2.4E-38 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CDC59_RS22295 780ff4a052f4d40f7281fc2dc6b9f760 322 Pfam PF02653 Branched-chain amino acid transport system / permease component 40 306 5.2E-43 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CDC59_RS12065 ee222b09c3315f5d9ea6ae54fe46a783 785 SUPERFAMILY SSF52540 367 672 1.22E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS12065 ee222b09c3315f5d9ea6ae54fe46a783 785 SUPERFAMILY SSF46785 713 777 3.93E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS12065 ee222b09c3315f5d9ea6ae54fe46a783 785 Gene3D G3DSA:1.10.10.10 714 768 7.2E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS12065 ee222b09c3315f5d9ea6ae54fe46a783 785 Pfam PF01580 FtsK/SpoIIIE family 392 601 3.2E-62 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CDC59_RS12065 ee222b09c3315f5d9ea6ae54fe46a783 785 SMART SM00843 712 777 4.0E-37 T 29-03-2018 IPR018541 FtsK gamma domain CDC59_RS12065 ee222b09c3315f5d9ea6ae54fe46a783 785 Gene3D G3DSA:3.40.50.300 216 639 4.9E-53 T 29-03-2018 CDC59_RS12065 ee222b09c3315f5d9ea6ae54fe46a783 785 Pfam PF09397 Ftsk gamma domain 714 774 5.8E-26 T 29-03-2018 IPR018541 FtsK gamma domain CDC59_RS12065 ee222b09c3315f5d9ea6ae54fe46a783 785 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 23 206 2.3E-49 T 29-03-2018 IPR025199 DNA translocase FtsK, 4TM region CDC59_RS08020 108a8403db05210081d54bf3a3d32d15 108 PRINTS PR00421 Thioredoxin family signature 72 83 4.4E-10 T 29-03-2018 CDC59_RS08020 108a8403db05210081d54bf3a3d32d15 108 PRINTS PR00421 Thioredoxin family signature 24 32 4.4E-10 T 29-03-2018 CDC59_RS08020 108a8403db05210081d54bf3a3d32d15 108 PRINTS PR00421 Thioredoxin family signature 32 41 4.4E-10 T 29-03-2018 CDC59_RS08020 108a8403db05210081d54bf3a3d32d15 108 TIGRFAM TIGR01068 thioredoxin: thioredoxin 9 107 2.0E-40 T 29-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CDC59_RS08020 108a8403db05210081d54bf3a3d32d15 108 Gene3D G3DSA:3.40.30.10 1 108 4.2E-37 T 29-03-2018 CDC59_RS08020 108a8403db05210081d54bf3a3d32d15 108 ProSitePatterns PS00194 Thioredoxin family active site. 25 43 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CDC59_RS08020 108a8403db05210081d54bf3a3d32d15 108 PIRSF PIRSF000077 2 108 2.0E-44 T 29-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CDC59_RS08020 108a8403db05210081d54bf3a3d32d15 108 SUPERFAMILY SSF52833 3 108 5.58E-41 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS08020 108a8403db05210081d54bf3a3d32d15 108 Pfam PF00085 Thioredoxin 5 107 1.2E-35 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 CDC59_RS00260 bd8cca6ef28552c70ba2ee9b63968daa 521 SMART SM00857 19 170 4.6E-39 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CDC59_RS00260 bd8cca6ef28552c70ba2ee9b63968daa 521 SUPERFAMILY SSF53041 18 169 9.02E-24 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CDC59_RS00260 bd8cca6ef28552c70ba2ee9b63968daa 521 Pfam PF00239 Resolvase, N terminal domain 20 160 1.5E-24 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CDC59_RS00260 bd8cca6ef28552c70ba2ee9b63968daa 521 Gene3D G3DSA:3.40.50.1390 14 179 8.2E-33 T 29-03-2018 CDC59_RS00260 bd8cca6ef28552c70ba2ee9b63968daa 521 Pfam PF07508 Recombinase 215 318 7.2E-16 T 29-03-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 CDC59_RS14900 53474af8da591ca73b1d5117d8d403c6 281 Gene3D G3DSA:3.40.50.1980 17 121 1.8E-20 T 29-03-2018 CDC59_RS14900 53474af8da591ca73b1d5117d8d403c6 281 Gene3D G3DSA:3.40.50.1980 122 279 6.2E-17 T 29-03-2018 CDC59_RS14900 53474af8da591ca73b1d5117d8d403c6 281 Pfam PF01497 Periplasmic binding protein 20 182 2.9E-12 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CDC59_RS14900 53474af8da591ca73b1d5117d8d403c6 281 SUPERFAMILY SSF53807 19 276 1.53E-35 T 29-03-2018 CDC59_RS06665 a3fb2867849a019f318bec379ffd994d 266 PIRSF PIRSF002854 3 266 2.8E-107 T 29-03-2018 IPR004872 Lipoprotein NlpA family CDC59_RS06665 a3fb2867849a019f318bec379ffd994d 266 Pfam PF03180 NLPA lipoprotein 31 266 1.9E-95 T 29-03-2018 IPR004872 Lipoprotein NlpA family CDC59_RS06665 a3fb2867849a019f318bec379ffd994d 266 Gene3D G3DSA:3.40.190.10 124 266 1.1E-54 T 29-03-2018 CDC59_RS06665 a3fb2867849a019f318bec379ffd994d 266 Gene3D G3DSA:3.40.190.10 30 123 3.4E-25 T 29-03-2018 CDC59_RS06665 a3fb2867849a019f318bec379ffd994d 266 SUPERFAMILY SSF53850 30 266 2.35E-91 T 29-03-2018 CDC59_RS06665 a3fb2867849a019f318bec379ffd994d 266 TIGRFAM TIGR00363 TIGR00363: lipoprotein, YaeC family 26 266 9.8E-79 T 29-03-2018 IPR004872 Lipoprotein NlpA family CDC59_RS05280 9d4f4cfa3be39aad754dd28f8acd0fe6 152 Pfam PF08765 Mor transcription activator family 97 147 1.4E-5 T 29-03-2018 IPR014875 Mor transcription activator CDC59_RS05280 9d4f4cfa3be39aad754dd28f8acd0fe6 152 Gene3D G3DSA:1.10.10.60 103 151 1.8E-9 T 29-03-2018 CDC59_RS05280 9d4f4cfa3be39aad754dd28f8acd0fe6 152 SUPERFAMILY SSF46689 97 145 6.63E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS23555 c6121b9ccdf1ce0f4e767f6eaeb63fc9 486 Pfam PF04607 Region found in RelA / SpoT proteins 52 181 4.8E-21 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 CDC59_RS23555 c6121b9ccdf1ce0f4e767f6eaeb63fc9 486 Gene3D G3DSA:3.30.460.10 6 164 3.1E-21 T 29-03-2018 CDC59_RS23555 c6121b9ccdf1ce0f4e767f6eaeb63fc9 486 Gene3D G3DSA:1.10.287.860 167 201 4.0E-15 T 29-03-2018 CDC59_RS23555 c6121b9ccdf1ce0f4e767f6eaeb63fc9 486 SUPERFAMILY SSF48452 261 407 4.64E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS23555 c6121b9ccdf1ce0f4e767f6eaeb63fc9 486 Gene3D G3DSA:1.25.40.10 202 486 2.6E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS23555 c6121b9ccdf1ce0f4e767f6eaeb63fc9 486 SMART SM00954 51 183 3.0E-16 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 CDC59_RS23555 c6121b9ccdf1ce0f4e767f6eaeb63fc9 486 SUPERFAMILY SSF81301 26 211 1.8E-33 T 29-03-2018 CDC59_RS22915 972569d26375eb8c3d1505ba53f43ee9 504 Gene3D G3DSA:3.40.309.10 276 472 6.1E-52 T 29-03-2018 CDC59_RS22915 972569d26375eb8c3d1505ba53f43ee9 504 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 257 264 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CDC59_RS22915 972569d26375eb8c3d1505ba53f43ee9 504 SUPERFAMILY SSF53720 22 493 2.62E-131 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CDC59_RS22915 972569d26375eb8c3d1505ba53f43ee9 504 Pfam PF00171 Aldehyde dehydrogenase family 24 483 2.0E-123 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CDC59_RS22915 972569d26375eb8c3d1505ba53f43ee9 504 Gene3D G3DSA:3.40.605.10 13 275 4.3E-71 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CDC59_RS20755 e0bc46d51ab7d41f9005f0f5628500b7 372 Gene3D G3DSA:2.40.160.20 12 371 5.2E-6 T 29-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CDC59_RS19410 4483088b6a54de92f20cc1c44ed0e1dc 212 SUPERFAMILY SSF50475 11 184 4.66E-39 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CDC59_RS19410 4483088b6a54de92f20cc1c44ed0e1dc 212 PIRSF PIRSF010372 1 211 1.6E-81 T 29-03-2018 IPR007396 Transcriptional regulator PAI 2-type CDC59_RS19410 4483088b6a54de92f20cc1c44ed0e1dc 212 Pfam PF04299 Putative FMN-binding domain 1 168 8.4E-64 T 29-03-2018 IPR007396 Transcriptional regulator PAI 2-type CDC59_RS19410 4483088b6a54de92f20cc1c44ed0e1dc 212 Gene3D G3DSA:2.30.110.10 1 210 4.7E-61 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CDC59_RS22875 37e0c7cfe4acc7baf2ff6532ea062b2e 318 Pfam PF00491 Arginase family 29 307 1.6E-59 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CDC59_RS22875 37e0c7cfe4acc7baf2ff6532ea062b2e 318 SUPERFAMILY SSF52768 9 311 1.26E-64 T 29-03-2018 CDC59_RS22875 37e0c7cfe4acc7baf2ff6532ea062b2e 318 Gene3D G3DSA:3.40.800.10 4 316 1.2E-67 T 29-03-2018 CDC59_RS22875 37e0c7cfe4acc7baf2ff6532ea062b2e 318 PIRSF PIRSF036979 11 314 7.8E-50 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CDC59_RS02875 4ec5261429bbafa71ab9d6229d8a3a5b 338 SUPERFAMILY SSF51735 128 298 3.46E-39 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS02875 4ec5261429bbafa71ab9d6229d8a3a5b 338 Pfam PF00107 Zinc-binding dehydrogenase 170 282 1.4E-15 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CDC59_RS02875 4ec5261429bbafa71ab9d6229d8a3a5b 338 Gene3D G3DSA:3.40.50.720 161 278 1.4E-17 T 29-03-2018 CDC59_RS02875 4ec5261429bbafa71ab9d6229d8a3a5b 338 SMART SM00829 20 334 1.2E-5 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CDC59_RS02875 4ec5261429bbafa71ab9d6229d8a3a5b 338 SUPERFAMILY SSF50129 5 155 9.89E-39 T 29-03-2018 IPR011032 GroES-like CDC59_RS02875 4ec5261429bbafa71ab9d6229d8a3a5b 338 Gene3D G3DSA:3.90.180.10 17 160 1.2E-26 T 29-03-2018 CDC59_RS02875 4ec5261429bbafa71ab9d6229d8a3a5b 338 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 40 112 2.3E-6 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CDC59_RS02875 4ec5261429bbafa71ab9d6229d8a3a5b 338 TIGRFAM TIGR02823 oxido_YhdH: putative quinone oxidoreductase, YhdH/YhfP family 34 336 1.4E-127 T 29-03-2018 IPR014188 Acrylyl-CoA reductase AcuI CDC59_RS01245 46d40a990a7253e98f864e6143fcd5b1 643 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 552 640 1.3E-5 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS01245 46d40a990a7253e98f864e6143fcd5b1 643 SMART SM00387 547 641 1.4E-5 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS01245 46d40a990a7253e98f864e6143fcd5b1 643 Gene3D G3DSA:3.30.565.10 412 640 7.0E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS01245 46d40a990a7253e98f864e6143fcd5b1 643 SUPERFAMILY SSF55874 509 639 4.06E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS17485 ae5d74869abb20d8c026305f39577b23 129 SUPERFAMILY SSF55331 2 126 2.93E-37 T 29-03-2018 IPR014347 Tautomerase/MIF superfamily CDC59_RS17485 ae5d74869abb20d8c026305f39577b23 129 Gene3D G3DSA:3.30.429.10 1 129 1.8E-26 T 29-03-2018 CDC59_RS17485 ae5d74869abb20d8c026305f39577b23 129 Pfam PF14552 Tautomerase enzyme 38 118 2.0E-26 T 29-03-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 CDC59_RS09065 e84ee28ba8d3fa1609eefef6a0c88a4f 300 Gene3D G3DSA:3.40.50.150 96 300 1.1E-37 T 29-03-2018 CDC59_RS09065 e84ee28ba8d3fa1609eefef6a0c88a4f 300 Gene3D G3DSA:1.10.8.10 6 95 2.9E-12 T 29-03-2018 CDC59_RS09065 e84ee28ba8d3fa1609eefef6a0c88a4f 300 PIRSF PIRSF037167 3 300 1.5E-125 T 29-03-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 CDC59_RS09065 e84ee28ba8d3fa1609eefef6a0c88a4f 300 Hamap MF_02125 50S ribosomal protein L3 glutamine methyltransferase [prmB]. 5 300 49.48 T 29-03-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 CDC59_RS09065 e84ee28ba8d3fa1609eefef6a0c88a4f 300 SUPERFAMILY SSF53335 15 282 2.26E-48 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS09065 e84ee28ba8d3fa1609eefef6a0c88a4f 300 Pfam PF05175 Methyltransferase small domain 135 217 2.1E-12 T 29-03-2018 IPR007848 Methyltransferase small domain GO:0008168 CDC59_RS09065 e84ee28ba8d3fa1609eefef6a0c88a4f 300 TIGRFAM TIGR03533 L3_gln_methyl: protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific 13 297 5.8E-122 T 29-03-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 CDC59_RS09065 e84ee28ba8d3fa1609eefef6a0c88a4f 300 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 14 297 2.2E-62 T 29-03-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 CDC59_RS09065 e84ee28ba8d3fa1609eefef6a0c88a4f 300 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 206 212 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CDC59_RS03920 dad4f1fc58d1853a03e4fce72f902f50 159 Gene3D G3DSA:2.60.120.10 5 147 2.0E-23 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CDC59_RS03920 dad4f1fc58d1853a03e4fce72f902f50 159 SUPERFAMILY SSF51182 4 148 2.3E-27 T 29-03-2018 IPR011051 RmlC-like cupin domain CDC59_RS03920 dad4f1fc58d1853a03e4fce72f902f50 159 Pfam PF07883 Cupin domain 49 117 1.8E-17 T 29-03-2018 IPR013096 Cupin 2, conserved barrel CDC59_RS06355 bee63821a2f0db9992e8c1a46eae8def 306 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 279 6.1E-34 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CDC59_RS06355 bee63821a2f0db9992e8c1a46eae8def 306 Gene3D G3DSA:1.10.3470.10 1 289 1.2E-39 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CDC59_RS01110 235062c9ea89c3cc38d10c1aa206d39e 165 SUPERFAMILY SSF51182 1 154 6.23E-59 T 29-03-2018 IPR011051 RmlC-like cupin domain CDC59_RS01110 235062c9ea89c3cc38d10c1aa206d39e 165 Gene3D G3DSA:2.60.120.480 1 164 3.9E-55 T 29-03-2018 IPR024060 Ureidoglycolate lyase domain GO:0004848 KEGG: 00230+4.3.2.3|MetaCyc: PWY-5694|MetaCyc: PWY-5705 CDC59_RS01110 235062c9ea89c3cc38d10c1aa206d39e 165 PIRSF PIRSF017306 1 154 2.0E-45 T 29-03-2018 IPR007247 Ureidoglycolate lyase GO:0000256|GO:0050385 KEGG: 00230+4.3.2.3|MetaCyc: PWY-5694|MetaCyc: PWY-5705 CDC59_RS01110 235062c9ea89c3cc38d10c1aa206d39e 165 Hamap MF_00616 Ureidoglycolate lyase [allA]. 1 156 39.34 T 29-03-2018 IPR023525 Ureidoglycolate lyase, bacterial GO:0000256|GO:0050385 KEGG: 00230+4.3.2.3|MetaCyc: PWY-5694|MetaCyc: PWY-5705 CDC59_RS01110 235062c9ea89c3cc38d10c1aa206d39e 165 Pfam PF04115 Ureidoglycolate lyase 1 153 6.8E-55 T 29-03-2018 IPR007247 Ureidoglycolate lyase GO:0000256|GO:0050385 KEGG: 00230+4.3.2.3|MetaCyc: PWY-5694|MetaCyc: PWY-5705 CDC59_RS12480 a8d0946693580de1436d7a14aa6a836c 389 SUPERFAMILY SSF53822 27 385 2.83E-73 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CDC59_RS12480 a8d0946693580de1436d7a14aa6a836c 389 Pfam PF13458 Periplasmic binding protein 28 375 4.2E-54 T 29-03-2018 IPR028081 Leucine-binding protein domain CDC59_RS12480 a8d0946693580de1436d7a14aa6a836c 389 Gene3D G3DSA:3.40.50.2300 26 152 5.3E-12 T 29-03-2018 CDC59_RS12480 a8d0946693580de1436d7a14aa6a836c 389 Gene3D G3DSA:3.40.50.2300 153 317 1.7E-32 T 29-03-2018 CDC59_RS09990 5e5a427a4c309d2bb636eadf708308bd 315 Gene3D G3DSA:1.10.3470.10 1 308 1.8E-43 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CDC59_RS09990 5e5a427a4c309d2bb636eadf708308bd 315 Pfam PF02653 Branched-chain amino acid transport system / permease component 7 274 1.2E-33 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CDC59_RS11805 6ce346a8050d7f8e2614a56c313f69af 160 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 1 151 42.142 T 29-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS11805 6ce346a8050d7f8e2614a56c313f69af 160 SUPERFAMILY SSF56770 9 153 4.97E-67 T 29-03-2018 CDC59_RS11805 6ce346a8050d7f8e2614a56c313f69af 160 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 11 152 7.0E-78 T 29-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS11805 6ce346a8050d7f8e2614a56c313f69af 160 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 118 134 - T 29-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS11805 6ce346a8050d7f8e2614a56c313f69af 160 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 37 145 1.8E-22 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS11805 6ce346a8050d7f8e2614a56c313f69af 160 Gene3D G3DSA:3.40.50.700 11 158 8.4E-49 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS02150 01d8431406e11f6e636490af4de841cc 168 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 3 160 27.689 T 29-03-2018 IPR022973 Ribosomal protein L10 CDC59_RS02150 01d8431406e11f6e636490af4de841cc 168 Pfam PF00466 Ribosomal protein L10 5 100 7.2E-24 T 29-03-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 CDC59_RS02150 01d8431406e11f6e636490af4de841cc 168 SUPERFAMILY SSF160369 4 159 2.88E-51 T 29-03-2018 CDC59_RS02150 01d8431406e11f6e636490af4de841cc 168 ProSitePatterns PS01109 Ribosomal protein L10 signature. 8 42 - T 29-03-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS08675 de26ad46c0273fa2ac08a3abb39903f0 95 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 21 92 19.662 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS08675 de26ad46c0273fa2ac08a3abb39903f0 95 Gene3D G3DSA:4.10.640.10 3 95 5.2E-29 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS08675 de26ad46c0273fa2ac08a3abb39903f0 95 SUPERFAMILY SSF46911 18 93 1.74E-27 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS08675 de26ad46c0273fa2ac08a3abb39903f0 95 PRINTS PR00974 Ribosomal protein S18 family signature 57 64 1.6E-14 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS08675 de26ad46c0273fa2ac08a3abb39903f0 95 PRINTS PR00974 Ribosomal protein S18 family signature 47 57 1.6E-14 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS08675 de26ad46c0273fa2ac08a3abb39903f0 95 PRINTS PR00974 Ribosomal protein S18 family signature 79 89 1.6E-14 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS08675 de26ad46c0273fa2ac08a3abb39903f0 95 PRINTS PR00974 Ribosomal protein S18 family signature 65 79 1.6E-14 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS08675 de26ad46c0273fa2ac08a3abb39903f0 95 ProSitePatterns PS00057 Ribosomal protein S18 signature. 40 63 - T 29-03-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS08675 de26ad46c0273fa2ac08a3abb39903f0 95 TIGRFAM TIGR00165 S18: ribosomal protein bS18 24 91 2.4E-32 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS08675 de26ad46c0273fa2ac08a3abb39903f0 95 Pfam PF01084 Ribosomal protein S18 38 87 1.6E-21 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS08675 de26ad46c0273fa2ac08a3abb39903f0 95 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 40 92 4.0E-25 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS15270 6746a1b70e31aacdbefd290b9b5a99df 363 Gene3D G3DSA:1.10.260.40 13 87 1.6E-5 T 29-03-2018 CDC59_RS15270 6746a1b70e31aacdbefd290b9b5a99df 363 SUPERFAMILY SSF47413 14 91 3.48E-11 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDC59_RS15270 6746a1b70e31aacdbefd290b9b5a99df 363 Pfam PF06114 IrrE N-terminal-like domain 246 324 8.6E-11 T 29-03-2018 IPR010359 IrrE N-terminal-like domain CDC59_RS12985 0d06138073d47fde43271c7434dc6174 159 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 74 155 1.4E-28 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CDC59_RS12985 0d06138073d47fde43271c7434dc6174 159 SUPERFAMILY SSF46767 71 155 4.71E-26 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CDC59_RS12985 0d06138073d47fde43271c7434dc6174 159 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 72 154 3.0E-24 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CDC59_RS12985 0d06138073d47fde43271c7434dc6174 159 Gene3D G3DSA:3.30.160.70 5 69 1.4E-5 T 29-03-2018 CDC59_RS12985 0d06138073d47fde43271c7434dc6174 159 Gene3D G3DSA:1.10.10.10 70 158 1.8E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS12985 0d06138073d47fde43271c7434dc6174 159 SUPERFAMILY SSF53155 7 77 1.33E-11 T 29-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CDC59_RS12985 0d06138073d47fde43271c7434dc6174 159 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 120 126 - T 29-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CDC59_RS17000 dd2cd2e32abb89978cbf16ab786e2416 295 Pfam PF13144 Chaperone for flagella basal body P-ring formation 88 293 1.0E-42 T 29-03-2018 IPR017585 Flagella basal body P-ring formation protein FlgA, C-terminal CDC59_RS17000 dd2cd2e32abb89978cbf16ab786e2416 295 SMART SM00858 171 233 2.7E-9 T 29-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 CDC59_RS17000 dd2cd2e32abb89978cbf16ab786e2416 295 Gene3D G3DSA:3.90.1210.10 171 236 9.1E-13 T 29-03-2018 CDC59_RS17000 dd2cd2e32abb89978cbf16ab786e2416 295 TIGRFAM TIGR03170 flgA_cterm: flagella basal body P-ring formation protein FlgA 159 294 9.1E-38 T 29-03-2018 IPR017585 Flagella basal body P-ring formation protein FlgA, C-terminal CDC59_RS01635 9da503fc878f65d2ec166ef24bb1de88 464 PIRSF PIRSF018788 2 461 7.8E-247 T 29-03-2018 IPR010628 Ethanolamine ammonia lyase large subunit GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 CDC59_RS01635 9da503fc878f65d2ec166ef24bb1de88 464 Gene3D G3DSA:1.10.220.70 57 141 9.9E-40 T 29-03-2018 CDC59_RS01635 9da503fc878f65d2ec166ef24bb1de88 464 Gene3D G3DSA:2.30.170.30 2 54 1.0E-23 T 29-03-2018 CDC59_RS01635 9da503fc878f65d2ec166ef24bb1de88 464 Pfam PF06751 Ethanolamine ammonia lyase large subunit (EutB) 13 441 2.3E-223 T 29-03-2018 IPR010628 Ethanolamine ammonia lyase large subunit GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 CDC59_RS01635 9da503fc878f65d2ec166ef24bb1de88 464 Gene3D G3DSA:3.20.20.70 144 451 4.4E-164 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS08475 65e4e7f167033b3f9e656573091c3e91 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 355 376 3.2E-77 T 29-03-2018 CDC59_RS08475 65e4e7f167033b3f9e656573091c3e91 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 188 213 3.2E-77 T 29-03-2018 CDC59_RS08475 65e4e7f167033b3f9e656573091c3e91 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 3.2E-77 T 29-03-2018 CDC59_RS08475 65e4e7f167033b3f9e656573091c3e91 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 47 62 3.2E-77 T 29-03-2018 CDC59_RS08475 65e4e7f167033b3f9e656573091c3e91 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 442 462 3.2E-77 T 29-03-2018 CDC59_RS08475 65e4e7f167033b3f9e656573091c3e91 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 152 161 3.2E-77 T 29-03-2018 CDC59_RS08475 65e4e7f167033b3f9e656573091c3e91 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 420 435 3.2E-77 T 29-03-2018 CDC59_RS08475 65e4e7f167033b3f9e656573091c3e91 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 277 291 3.2E-77 T 29-03-2018 CDC59_RS08475 65e4e7f167033b3f9e656573091c3e91 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 320 327 3.2E-77 T 29-03-2018 CDC59_RS08475 65e4e7f167033b3f9e656573091c3e91 478 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 4 478 2.8E-164 T 29-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CDC59_RS08475 65e4e7f167033b3f9e656573091c3e91 478 SUPERFAMILY SSF51905 1 350 1.46E-59 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS08475 65e4e7f167033b3f9e656573091c3e91 478 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 340 2.3E-71 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS08475 65e4e7f167033b3f9e656573091c3e91 478 Gene3D G3DSA:1.10.287.990 53 114 5.5E-24 T 29-03-2018 CDC59_RS08475 65e4e7f167033b3f9e656573091c3e91 478 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 359 468 3.1E-37 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CDC59_RS08475 65e4e7f167033b3f9e656573091c3e91 478 SUPERFAMILY SSF55424 355 476 1.25E-41 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CDC59_RS08475 65e4e7f167033b3f9e656573091c3e91 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 188 206 5.8E-41 T 29-03-2018 CDC59_RS08475 65e4e7f167033b3f9e656573091c3e91 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 276 292 5.8E-41 T 29-03-2018 CDC59_RS08475 65e4e7f167033b3f9e656573091c3e91 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 5.8E-41 T 29-03-2018 CDC59_RS08475 65e4e7f167033b3f9e656573091c3e91 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 305 327 5.8E-41 T 29-03-2018 CDC59_RS08475 65e4e7f167033b3f9e656573091c3e91 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 167 5.8E-41 T 29-03-2018 CDC59_RS08475 65e4e7f167033b3f9e656573091c3e91 478 Gene3D G3DSA:3.30.390.30 347 477 7.3E-42 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CDC59_RS08475 65e4e7f167033b3f9e656573091c3e91 478 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 48 58 - T 29-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CDC59_RS08475 65e4e7f167033b3f9e656573091c3e91 478 Gene3D G3DSA:3.50.50.60 1 52 1.4E-8 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS08475 65e4e7f167033b3f9e656573091c3e91 478 Gene3D G3DSA:3.40.50.720 172 346 1.8E-39 T 29-03-2018 CDC59_RS08475 65e4e7f167033b3f9e656573091c3e91 478 PIRSF PIRSF000350 1 477 2.2E-86 T 29-03-2018 CDC59_RS06165 3064845aea70db0897ff17c4ee20c40f 349 SUPERFAMILY SSF56281 53 339 9.04E-55 T 29-03-2018 IPR001279 Metallo-beta-lactamase CDC59_RS06165 3064845aea70db0897ff17c4ee20c40f 349 SMART SM00849 111 317 1.0E-19 T 29-03-2018 IPR001279 Metallo-beta-lactamase CDC59_RS06165 3064845aea70db0897ff17c4ee20c40f 349 Gene3D G3DSA:3.60.15.10 49 347 9.5E-60 T 29-03-2018 IPR001279 Metallo-beta-lactamase CDC59_RS06165 3064845aea70db0897ff17c4ee20c40f 349 Pfam PF00753 Metallo-beta-lactamase superfamily 110 304 1.3E-20 T 29-03-2018 IPR001279 Metallo-beta-lactamase CDC59_RS11345 664cf1151d497be8182cab1722c89064 265 Pfam PF02698 DUF218 domain 87 254 3.7E-24 T 29-03-2018 IPR003848 Domain of unknown function DUF218 CDC59_RS11345 664cf1151d497be8182cab1722c89064 265 Gene3D G3DSA:3.40.50.620 76 221 8.4E-26 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDC59_RS01115 2ac1b8d26fe54a2d0a9731215c69e27c 424 SUPERFAMILY SSF53187 335 421 1.5E-45 T 29-03-2018 CDC59_RS01115 2ac1b8d26fe54a2d0a9731215c69e27c 424 SUPERFAMILY SSF53187 14 210 1.5E-45 T 29-03-2018 CDC59_RS01115 2ac1b8d26fe54a2d0a9731215c69e27c 424 Gene3D G3DSA:3.40.630.10 2 316 4.7E-52 T 29-03-2018 CDC59_RS01115 2ac1b8d26fe54a2d0a9731215c69e27c 424 Pfam PF07687 Peptidase dimerisation domain 208 318 5.7E-18 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CDC59_RS01115 2ac1b8d26fe54a2d0a9731215c69e27c 424 Pfam PF01546 Peptidase family M20/M25/M40 98 418 2.5E-25 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CDC59_RS01115 2ac1b8d26fe54a2d0a9731215c69e27c 424 SUPERFAMILY SSF55031 211 330 9.27E-24 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CDC59_RS01115 2ac1b8d26fe54a2d0a9731215c69e27c 424 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 97 106 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CDC59_RS11270 c8b823a977f74c76819f370b2e9e3a25 688 Pfam PF00474 Sodium:solute symporter family 74 237 9.2E-31 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CDC59_RS11270 c8b823a977f74c76819f370b2e9e3a25 688 Pfam PF00474 Sodium:solute symporter family 502 617 1.7E-21 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CDC59_RS11270 c8b823a977f74c76819f370b2e9e3a25 688 TIGRFAM TIGR03648 Na_symport_lg: probable sodium:solute symporter, VC_2705 subfamily 49 687 3.1E-213 T 29-03-2018 IPR019899 Sodium/solute symporter, VC2705 subfamily CDC59_RS11270 c8b823a977f74c76819f370b2e9e3a25 688 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 599 619 - T 29-03-2018 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 CDC59_RS17180 841c4ec90291d4e71be61c12ea133bc8 330 Pfam PF14842 FliG N-terminal domain 5 102 1.4E-24 T 29-03-2018 IPR028263 Flagellar motor switch protein FliG, N-terminal domain CDC59_RS17180 841c4ec90291d4e71be61c12ea133bc8 330 Pfam PF01706 FliG C-terminal domain 215 321 4.1E-42 T 29-03-2018 IPR023087 Flagellar motor switch protein FliG, C-terminal CDC59_RS17180 841c4ec90291d4e71be61c12ea133bc8 330 Pfam PF14841 FliG middle domain 113 185 1.8E-25 T 29-03-2018 IPR032779 Flagellar motor switch protein FliG, middle domain CDC59_RS17180 841c4ec90291d4e71be61c12ea133bc8 330 PRINTS PR00954 Flagellar motor switch protein FliG signature 223 243 3.0E-59 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CDC59_RS17180 841c4ec90291d4e71be61c12ea133bc8 330 PRINTS PR00954 Flagellar motor switch protein FliG signature 32 58 3.0E-59 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CDC59_RS17180 841c4ec90291d4e71be61c12ea133bc8 330 PRINTS PR00954 Flagellar motor switch protein FliG signature 245 265 3.0E-59 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CDC59_RS17180 841c4ec90291d4e71be61c12ea133bc8 330 PRINTS PR00954 Flagellar motor switch protein FliG signature 3 19 3.0E-59 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CDC59_RS17180 841c4ec90291d4e71be61c12ea133bc8 330 PRINTS PR00954 Flagellar motor switch protein FliG signature 111 134 3.0E-59 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CDC59_RS17180 841c4ec90291d4e71be61c12ea133bc8 330 PRINTS PR00954 Flagellar motor switch protein FliG signature 269 295 3.0E-59 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CDC59_RS17180 841c4ec90291d4e71be61c12ea133bc8 330 PRINTS PR00954 Flagellar motor switch protein FliG signature 192 217 3.0E-59 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CDC59_RS17180 841c4ec90291d4e71be61c12ea133bc8 330 Gene3D G3DSA:1.10.220.30 69 188 9.5E-20 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical CDC59_RS17180 841c4ec90291d4e71be61c12ea133bc8 330 Gene3D G3DSA:1.10.220.30 192 330 2.4E-32 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical CDC59_RS17180 841c4ec90291d4e71be61c12ea133bc8 330 TIGRFAM TIGR00207 fliG: flagellar motor switch protein FliG 5 329 1.1E-104 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CDC59_RS17180 841c4ec90291d4e71be61c12ea133bc8 330 SUPERFAMILY SSF48029 111 322 9.94E-66 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical CDC59_RS17180 841c4ec90291d4e71be61c12ea133bc8 330 Gene3D G3DSA:1.10.220.30 1 64 9.3E-8 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical CDC59_RS17180 841c4ec90291d4e71be61c12ea133bc8 330 SUPERFAMILY SSF48029 2 112 2.09E-20 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical CDC59_RS17180 841c4ec90291d4e71be61c12ea133bc8 330 PIRSF PIRSF003161 1 330 1.9E-111 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CDC59_RS16675 3254e63e10e55d36452f9cdb899a200f 187 Gene3D G3DSA:2.130.10.10 3 180 1.6E-9 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CDC59_RS16675 3254e63e10e55d36452f9cdb899a200f 187 SUPERFAMILY SSF50965 8 175 4.32E-6 T 29-03-2018 IPR011043 Galactose oxidase/kelch, beta-propeller CDC59_RS21175 7455bfad246c4e4d090e88f5a6d2df4f 549 Pfam PF07690 Major Facilitator Superfamily 33 433 4.6E-44 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDC59_RS21175 7455bfad246c4e4d090e88f5a6d2df4f 549 SUPERFAMILY SSF103473 21 481 4.58E-47 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS21175 7455bfad246c4e4d090e88f5a6d2df4f 549 Gene3D G3DSA:1.20.1250.20 256 492 4.7E-23 T 29-03-2018 CDC59_RS21175 7455bfad246c4e4d090e88f5a6d2df4f 549 Gene3D G3DSA:1.20.1250.20 17 242 3.1E-19 T 29-03-2018 CDC59_RS10250 ba7144a81fb6062f03c58ca847055bf4 182 SUPERFAMILY SSF52833 18 181 1.84E-44 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS10250 ba7144a81fb6062f03c58ca847055bf4 182 Pfam PF00578 AhpC/TSA family 14 143 1.6E-25 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CDC59_RS10250 ba7144a81fb6062f03c58ca847055bf4 182 Gene3D G3DSA:3.40.30.10 1 167 3.0E-29 T 29-03-2018 CDC59_RS10250 ba7144a81fb6062f03c58ca847055bf4 182 PIRSF PIRSF000239 1 182 1.4E-41 T 29-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CDC59_RS18965 dd3c04cc5b110afa43f680becceae53c 270 Pfam PF05138 Phenylacetic acid catabolic protein 3 270 3.5E-90 T 29-03-2018 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 CDC59_RS18965 dd3c04cc5b110afa43f680becceae53c 270 Gene3D G3DSA:1.20.1260.10 2 270 1.4E-69 T 29-03-2018 IPR012347 Ferritin-related CDC59_RS18965 dd3c04cc5b110afa43f680becceae53c 270 SUPERFAMILY SSF47240 8 264 9.73E-77 T 29-03-2018 IPR009078 Ferritin-like superfamily CDC59_RS18965 dd3c04cc5b110afa43f680becceae53c 270 TIGRFAM TIGR02158 PA_CoA_Oxy3: phenylacetate-CoA oxygenase, PaaI subunit 17 270 5.9E-82 T 29-03-2018 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 CDC59_RS18965 dd3c04cc5b110afa43f680becceae53c 270 PIRSF PIRSF037834 1 270 7.2E-99 T 29-03-2018 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 CDC59_RS17210 779e35191a42a7609af82e847a4f4f64 488 Gene3D G3DSA:3.30.70.270 316 488 7.3E-53 T 29-03-2018 CDC59_RS17210 779e35191a42a7609af82e847a4f4f64 488 Gene3D G3DSA:3.30.450.20 57 168 2.7E-13 T 29-03-2018 CDC59_RS17210 779e35191a42a7609af82e847a4f4f64 488 SUPERFAMILY SSF55073 328 487 1.28E-45 T 29-03-2018 IPR029787 Nucleotide cyclase CDC59_RS17210 779e35191a42a7609af82e847a4f4f64 488 Pfam PF00990 Diguanylate cyclase, GGDEF domain 323 485 3.9E-49 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS17210 779e35191a42a7609af82e847a4f4f64 488 Pfam PF02743 Cache domain 42 269 1.5E-15 T 29-03-2018 IPR033479 Double Cache domain 1 CDC59_RS17210 779e35191a42a7609af82e847a4f4f64 488 SMART SM00267 312 488 7.4E-60 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS17210 779e35191a42a7609af82e847a4f4f64 488 Gene3D G3DSA:3.30.450.20 169 284 9.7E-11 T 29-03-2018 CDC59_RS17210 779e35191a42a7609af82e847a4f4f64 488 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 321 487 7.3E-53 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS11610 c0beea412f4e47cc9f1925214abc28f2 420 Gene3D G3DSA:1.20.140.10 255 415 2.7E-42 T 29-03-2018 CDC59_RS11610 c0beea412f4e47cc9f1925214abc28f2 420 SUPERFAMILY SSF56645 2 263 6.28E-63 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CDC59_RS11610 c0beea412f4e47cc9f1925214abc28f2 420 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 137 233 1.6E-20 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CDC59_RS11610 c0beea412f4e47cc9f1925214abc28f2 420 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 133 3.3E-10 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CDC59_RS11610 c0beea412f4e47cc9f1925214abc28f2 420 Gene3D G3DSA:1.10.540.10 1 137 2.3E-30 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CDC59_RS11610 c0beea412f4e47cc9f1925214abc28f2 420 Gene3D G3DSA:2.40.110.10 138 254 5.8E-34 T 29-03-2018 CDC59_RS11610 c0beea412f4e47cc9f1925214abc28f2 420 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 250 398 3.8E-36 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CDC59_RS11610 c0beea412f4e47cc9f1925214abc28f2 420 SUPERFAMILY SSF47203 248 404 6.93E-44 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CDC59_RS22110 e770a52c7aab00acafd797ee780787d6 404 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 240 253 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CDC59_RS22110 e770a52c7aab00acafd797ee780787d6 404 SUPERFAMILY SSF53383 9 402 7.48E-106 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS22110 e770a52c7aab00acafd797ee780787d6 404 Pfam PF00155 Aminotransferase class I and II 36 396 7.9E-72 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CDC59_RS22110 e770a52c7aab00acafd797ee780787d6 404 Gene3D G3DSA:3.90.1150.10 279 404 2.9E-29 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS22110 e770a52c7aab00acafd797ee780787d6 404 Gene3D G3DSA:3.40.640.10 49 278 8.1E-48 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDC59_RS19825 d1458543094eeda193fe8d155486eca3 315 SUPERFAMILY SSF52540 86 200 6.98E-27 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS19825 d1458543094eeda193fe8d155486eca3 315 Gene3D G3DSA:3.40.50.300 85 201 6.2E-22 T 29-03-2018 CDC59_RS10010 60d6aab892bab25897993a50b87b049f 128 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 5 126 8.2E-60 T 29-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CDC59_RS10010 60d6aab892bab25897993a50b87b049f 128 Pfam PF01641 SelR domain 9 126 2.2E-55 T 29-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CDC59_RS10010 60d6aab892bab25897993a50b87b049f 128 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 6 128 36.772 T 29-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CDC59_RS10010 60d6aab892bab25897993a50b87b049f 128 SUPERFAMILY SSF51316 4 126 2.69E-60 T 29-03-2018 IPR011057 Mss4-like CDC59_RS10010 60d6aab892bab25897993a50b87b049f 128 Gene3D G3DSA:2.170.150.20 1 128 5.7E-62 T 29-03-2018 CDC59_RS18150 b24471ad83ce264f3bd369bd796f8a17 716 ProSitePatterns PS00080 Multicopper oxidases signature 2. 685 696 - T 29-03-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 CDC59_RS18150 b24471ad83ce264f3bd369bd796f8a17 716 SUPERFAMILY SSF49503 388 433 6.65E-12 T 29-03-2018 IPR008972 Cupredoxin CDC59_RS18150 b24471ad83ce264f3bd369bd796f8a17 716 SUPERFAMILY SSF49503 302 360 6.65E-12 T 29-03-2018 IPR008972 Cupredoxin CDC59_RS18150 b24471ad83ce264f3bd369bd796f8a17 716 Gene3D G3DSA:2.60.40.420 60 241 1.6E-26 T 29-03-2018 IPR008972 Cupredoxin CDC59_RS18150 b24471ad83ce264f3bd369bd796f8a17 716 Gene3D G3DSA:2.60.40.420 242 486 3.6E-20 T 29-03-2018 IPR008972 Cupredoxin CDC59_RS18150 b24471ad83ce264f3bd369bd796f8a17 716 Pfam PF07732 Multicopper oxidase 137 251 1.6E-12 T 29-03-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 CDC59_RS18150 b24471ad83ce264f3bd369bd796f8a17 716 Gene3D G3DSA:2.60.40.420 525 708 1.2E-18 T 29-03-2018 IPR008972 Cupredoxin CDC59_RS18150 b24471ad83ce264f3bd369bd796f8a17 716 SUPERFAMILY SSF49503 584 702 2.89E-14 T 29-03-2018 IPR008972 Cupredoxin CDC59_RS18150 b24471ad83ce264f3bd369bd796f8a17 716 Pfam PF07731 Multicopper oxidase 565 701 2.9E-12 T 29-03-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 CDC59_RS18150 b24471ad83ce264f3bd369bd796f8a17 716 SUPERFAMILY SSF49503 139 253 3.97E-23 T 29-03-2018 IPR008972 Cupredoxin CDC59_RS18150 b24471ad83ce264f3bd369bd796f8a17 716 ProSitePatterns PS00079 Multicopper oxidases signature 1. 680 700 - T 29-03-2018 IPR033138 Multicopper oxidases, conserved site CDC59_RS13925 270d7b4caf3cf2ceabd67f64d9543516 622 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 18 608 33.475 T 29-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 CDC59_RS13925 270d7b4caf3cf2ceabd67f64d9543516 622 SUPERFAMILY SSF55261 309 434 1.96E-43 T 29-03-2018 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 CDC59_RS13925 270d7b4caf3cf2ceabd67f64d9543516 622 Pfam PF00152 tRNA synthetases class II (D, K and N) 136 582 4.1E-107 T 29-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDC59_RS13925 270d7b4caf3cf2ceabd67f64d9543516 622 Pfam PF01336 OB-fold nucleic acid binding domain 35 119 6.8E-16 T 29-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CDC59_RS13925 270d7b4caf3cf2ceabd67f64d9543516 622 PRINTS PR01042 Aspartyl-tRNA synthetase signature 542 556 1.7E-26 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDC59_RS13925 270d7b4caf3cf2ceabd67f64d9543516 622 PRINTS PR01042 Aspartyl-tRNA synthetase signature 225 238 1.7E-26 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDC59_RS13925 270d7b4caf3cf2ceabd67f64d9543516 622 PRINTS PR01042 Aspartyl-tRNA synthetase signature 498 514 1.7E-26 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDC59_RS13925 270d7b4caf3cf2ceabd67f64d9543516 622 PRINTS PR01042 Aspartyl-tRNA synthetase signature 208 220 1.7E-26 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDC59_RS13925 270d7b4caf3cf2ceabd67f64d9543516 622 Gene3D G3DSA:3.30.930.10 149 610 7.9E-108 T 29-03-2018 CDC59_RS13925 270d7b4caf3cf2ceabd67f64d9543516 622 SUPERFAMILY SSF50249 18 122 1.58E-34 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDC59_RS13925 270d7b4caf3cf2ceabd67f64d9543516 622 Pfam PF02938 GAD domain 326 425 7.2E-27 T 29-03-2018 IPR029351 GAD domain Reactome: R-HSA-379726 CDC59_RS13925 270d7b4caf3cf2ceabd67f64d9543516 622 Gene3D G3DSA:2.40.50.140 7 125 7.6E-27 T 29-03-2018 CDC59_RS13925 270d7b4caf3cf2ceabd67f64d9543516 622 SUPERFAMILY SSF55681 448 608 1.43E-104 T 29-03-2018 CDC59_RS13925 270d7b4caf3cf2ceabd67f64d9543516 622 SUPERFAMILY SSF55681 128 310 1.43E-104 T 29-03-2018 CDC59_RS13925 270d7b4caf3cf2ceabd67f64d9543516 622 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 18 606 6.1E-250 T 29-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 CDC59_RS22275 029f25c25c08016616c87cd35f7ab84e 348 Pfam PF09851 Short C-terminal domain 314 339 5.0E-7 T 29-03-2018 IPR018649 SHOCT domain CDC59_RS22275 029f25c25c08016616c87cd35f7ab84e 348 Pfam PF13421 SPFH domain-Band 7 family 26 235 1.9E-71 T 29-03-2018 IPR033880 SPFH domain, YdjI-like CDC59_RS22275 029f25c25c08016616c87cd35f7ab84e 348 SUPERFAMILY SSF117892 90 232 2.22E-11 T 29-03-2018 IPR001107 Band 7 domain CDC59_RS06365 882719b2747e665289e3f86949e2fc96 513 SUPERFAMILY SSF52540 262 476 2.61E-33 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS06365 882719b2747e665289e3f86949e2fc96 513 Gene3D G3DSA:3.40.50.300 252 485 1.5E-25 T 29-03-2018 CDC59_RS06365 882719b2747e665289e3f86949e2fc96 513 Gene3D G3DSA:3.40.50.300 1 224 7.3E-56 T 29-03-2018 CDC59_RS06365 882719b2747e665289e3f86949e2fc96 513 SMART SM00382 20 216 2.0E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS06365 882719b2747e665289e3f86949e2fc96 513 Pfam PF00005 ABC transporter 264 423 9.5E-10 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS06365 882719b2747e665289e3f86949e2fc96 513 Pfam PF00005 ABC transporter 12 160 1.2E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS06365 882719b2747e665289e3f86949e2fc96 513 ProSitePatterns PS00211 ABC transporters family signature. 396 410 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS06365 882719b2747e665289e3f86949e2fc96 513 SUPERFAMILY SSF52540 2 215 3.63E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS06365 882719b2747e665289e3f86949e2fc96 513 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS03925 3eb376ab0e3b0fd9d740c741ae273d05 131 Gene3D G3DSA:3.10.180.10 1 126 8.0E-17 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CDC59_RS03925 3eb376ab0e3b0fd9d740c741ae273d05 131 SUPERFAMILY SSF54593 3 121 3.85E-20 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CDC59_RS03925 3eb376ab0e3b0fd9d740c741ae273d05 131 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 115 4.8E-8 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CDC59_RS06740 6c0d69b5a1c4ccc2935dc1cac20db18c 227 SUPERFAMILY SSF55811 61 218 4.06E-33 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CDC59_RS06740 6c0d69b5a1c4ccc2935dc1cac20db18c 227 Gene3D G3DSA:3.90.79.10 38 227 4.6E-41 T 29-03-2018 CDC59_RS06740 6c0d69b5a1c4ccc2935dc1cac20db18c 227 Pfam PF00293 NUDIX domain 62 188 7.0E-12 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CDC59_RS00905 05b7ea93ba5a011d02a4896d5acfcd91 599 Pfam PF00672 HAMP domain 297 342 6.0E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CDC59_RS00905 05b7ea93ba5a011d02a4896d5acfcd91 599 Pfam PF02743 Cache domain 98 255 6.1E-21 T 29-03-2018 IPR033479 Double Cache domain 1 CDC59_RS00905 05b7ea93ba5a011d02a4896d5acfcd91 599 Gene3D G3DSA:3.30.450.20 26 154 3.4E-17 T 29-03-2018 CDC59_RS00905 05b7ea93ba5a011d02a4896d5acfcd91 599 SMART SM00304 293 347 2.0E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CDC59_RS00905 05b7ea93ba5a011d02a4896d5acfcd91 599 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 446 473 9.1E-46 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS00905 05b7ea93ba5a011d02a4896d5acfcd91 599 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 523 552 9.1E-46 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS00905 05b7ea93ba5a011d02a4896d5acfcd91 599 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 369 398 9.1E-46 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS00905 05b7ea93ba5a011d02a4896d5acfcd91 599 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 475 504 9.1E-46 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS00905 05b7ea93ba5a011d02a4896d5acfcd91 599 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 408 562 6.3E-50 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CDC59_RS00905 05b7ea93ba5a011d02a4896d5acfcd91 599 SUPERFAMILY SSF58104 315 596 3.27E-68 T 29-03-2018 CDC59_RS00905 05b7ea93ba5a011d02a4896d5acfcd91 599 Gene3D G3DSA:3.30.450.20 155 266 1.8E-17 T 29-03-2018 CDC59_RS00905 05b7ea93ba5a011d02a4896d5acfcd91 599 SMART SM00283 348 595 1.8E-77 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CDC59_RS00905 05b7ea93ba5a011d02a4896d5acfcd91 599 SUPERFAMILY SSF103190 111 163 4.97E-9 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CDC59_RS00905 05b7ea93ba5a011d02a4896d5acfcd91 599 Gene3D G3DSA:1.10.287.950 401 599 8.0E-47 T 29-03-2018 CDC59_RS00905 05b7ea93ba5a011d02a4896d5acfcd91 599 Gene3D G3DSA:1.10.287.950 267 400 9.8E-13 T 29-03-2018 CDC59_RS14305 8861ae7d78a5566e1fa1f20696e77860 316 SMART SM01400 6 123 1.8E-79 T 29-03-2018 CDC59_RS14305 8861ae7d78a5566e1fa1f20696e77860 316 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 6 315 48.913 T 29-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CDC59_RS14305 8861ae7d78a5566e1fa1f20696e77860 316 Pfam PF14572 Phosphoribosyl synthetase-associated domain 205 314 1.9E-28 T 29-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CDC59_RS14305 8861ae7d78a5566e1fa1f20696e77860 316 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 131 146 - T 29-03-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 CDC59_RS14305 8861ae7d78a5566e1fa1f20696e77860 316 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 6 123 1.5E-49 T 29-03-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CDC59_RS14305 8861ae7d78a5566e1fa1f20696e77860 316 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 7 314 2.8E-123 T 29-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CDC59_RS14305 8861ae7d78a5566e1fa1f20696e77860 316 Gene3D G3DSA:3.40.50.2020 159 291 1.5E-45 T 29-03-2018 CDC59_RS14305 8861ae7d78a5566e1fa1f20696e77860 316 SUPERFAMILY SSF53271 71 305 1.28E-65 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CDC59_RS14305 8861ae7d78a5566e1fa1f20696e77860 316 Gene3D G3DSA:3.40.50.2020 3 158 4.0E-68 T 29-03-2018 CDC59_RS14975 e98c3684bfcd6cbccfb5d62588b9098a 144 SUPERFAMILY SSF54427 33 143 4.56E-33 T 29-03-2018 IPR032710 NTF2-like domain CDC59_RS14975 e98c3684bfcd6cbccfb5d62588b9098a 144 Gene3D G3DSA:3.10.450.50 12 144 3.9E-44 T 29-03-2018 CDC59_RS14975 e98c3684bfcd6cbccfb5d62588b9098a 144 Hamap MF_00612 UPF0225 protein YchJ [ychJ]. 10 142 30.104 T 29-03-2018 IPR023006 Uncharacterised protein family UPF0225 CDC59_RS13345 224d8448f20505995417d47b418bceff 479 SUPERFAMILY SSF51621 166 343 8.03E-89 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CDC59_RS13345 224d8448f20505995417d47b418bceff 479 SUPERFAMILY SSF51621 2 76 8.03E-89 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CDC59_RS13345 224d8448f20505995417d47b418bceff 479 Pfam PF02887 Pyruvate kinase, alpha/beta domain 362 474 3.3E-26 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CDC59_RS13345 224d8448f20505995417d47b418bceff 479 PRINTS PR01050 Pyruvate kinase family signature 248 272 7.3E-46 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CDC59_RS13345 224d8448f20505995417d47b418bceff 479 PRINTS PR01050 Pyruvate kinase family signature 317 333 7.3E-46 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CDC59_RS13345 224d8448f20505995417d47b418bceff 479 PRINTS PR01050 Pyruvate kinase family signature 60 76 7.3E-46 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CDC59_RS13345 224d8448f20505995417d47b418bceff 479 PRINTS PR01050 Pyruvate kinase family signature 185 199 7.3E-46 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CDC59_RS13345 224d8448f20505995417d47b418bceff 479 PRINTS PR01050 Pyruvate kinase family signature 273 297 7.3E-46 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CDC59_RS13345 224d8448f20505995417d47b418bceff 479 PRINTS PR01050 Pyruvate kinase family signature 298 316 7.3E-46 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CDC59_RS13345 224d8448f20505995417d47b418bceff 479 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 3 476 7.2E-152 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CDC59_RS13345 224d8448f20505995417d47b418bceff 479 Gene3D G3DSA:3.20.20.60 1 76 4.3E-17 T 29-03-2018 CDC59_RS13345 224d8448f20505995417d47b418bceff 479 SUPERFAMILY SSF50800 71 164 1.45E-25 T 29-03-2018 IPR011037 Pyruvate kinase-like, insert domain CDC59_RS13345 224d8448f20505995417d47b418bceff 479 Gene3D G3DSA:2.40.33.10 77 166 4.9E-23 T 29-03-2018 CDC59_RS13345 224d8448f20505995417d47b418bceff 479 Pfam PF00224 Pyruvate kinase, barrel domain 3 342 4.8E-116 T 29-03-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CDC59_RS13345 224d8448f20505995417d47b418bceff 479 Gene3D G3DSA:3.20.20.60 167 325 3.6E-55 T 29-03-2018 CDC59_RS13345 224d8448f20505995417d47b418bceff 479 SUPERFAMILY SSF52935 327 477 3.66E-36 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CDC59_RS13345 224d8448f20505995417d47b418bceff 479 Gene3D G3DSA:3.40.1380.20 326 477 5.0E-44 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CDC59_RS05530 8419719421f42d92a8034832efce9698 300 Gene3D G3DSA:3.40.50.1100 140 300 1.8E-46 T 29-03-2018 CDC59_RS05530 8419719421f42d92a8034832efce9698 300 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 36 54 - T 29-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 CDC59_RS05530 8419719421f42d92a8034832efce9698 300 TIGRFAM TIGR01136 cysKM: cysteine synthase 6 298 5.4E-116 T 29-03-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 CDC59_RS05530 8419719421f42d92a8034832efce9698 300 SUPERFAMILY SSF53686 2 298 1.57E-88 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CDC59_RS05530 8419719421f42d92a8034832efce9698 300 Gene3D G3DSA:3.40.50.1100 44 139 3.0E-33 T 29-03-2018 CDC59_RS05530 8419719421f42d92a8034832efce9698 300 TIGRFAM TIGR01138 cysM: cysteine synthase B 5 298 5.6E-135 T 29-03-2018 IPR005858 Cysteine synthase CysM GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 CDC59_RS05530 8419719421f42d92a8034832efce9698 300 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 7 287 9.1E-64 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CDC59_RS09170 46a038279d306018a32e5b2242ea12ad 259 Gene3D G3DSA:3.40.1180.10 2 244 1.9E-86 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CDC59_RS09170 46a038279d306018a32e5b2242ea12ad 259 SUPERFAMILY SSF64005 13 236 4.32E-83 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CDC59_RS09170 46a038279d306018a32e5b2242ea12ad 259 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 15 241 39.937 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CDC59_RS09170 46a038279d306018a32e5b2242ea12ad 259 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 186 203 - T 29-03-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199 CDC59_RS09170 46a038279d306018a32e5b2242ea12ad 259 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 16 240 1.7E-84 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CDC59_RS09170 46a038279d306018a32e5b2242ea12ad 259 Pfam PF01255 Putative undecaprenyl diphosphate synthase 22 240 1.9E-76 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CDC59_RS01700 d1f11588295a74f53e31fba68027a24e 809 Pfam PF00263 Bacterial type II and III secretion system protein 538 705 3.0E-53 T 29-03-2018 IPR004846 Type II/III secretion system GO:0009306 CDC59_RS01700 d1f11588295a74f53e31fba68027a24e 809 TIGRFAM TIGR02517 type_II_gspD: type II secretion system protein D 57 710 4.5E-195 T 29-03-2018 IPR013356 Type II secretion system GspD GO:0008565|GO:0015627|GO:0015628|GO:0019867 CDC59_RS01700 d1f11588295a74f53e31fba68027a24e 809 PRINTS PR01032 Gene IV protein signature 517 540 1.2E-14 T 29-03-2018 CDC59_RS01700 d1f11588295a74f53e31fba68027a24e 809 PRINTS PR01032 Gene IV protein signature 559 582 1.2E-14 T 29-03-2018 CDC59_RS01700 d1f11588295a74f53e31fba68027a24e 809 PRINTS PR01032 Gene IV protein signature 632 660 1.2E-14 T 29-03-2018 CDC59_RS01700 d1f11588295a74f53e31fba68027a24e 809 PRINTS PR01032 Gene IV protein signature 685 707 1.2E-14 T 29-03-2018 CDC59_RS01700 d1f11588295a74f53e31fba68027a24e 809 PRINTS PR00811 Bacterial general secretion pathway protein D signature 437 447 1.2E-29 T 29-03-2018 IPR001775 GspD/PilQ family CDC59_RS01700 d1f11588295a74f53e31fba68027a24e 809 PRINTS PR00811 Bacterial general secretion pathway protein D signature 692 706 1.2E-29 T 29-03-2018 IPR001775 GspD/PilQ family CDC59_RS01700 d1f11588295a74f53e31fba68027a24e 809 PRINTS PR00811 Bacterial general secretion pathway protein D signature 534 558 1.2E-29 T 29-03-2018 IPR001775 GspD/PilQ family CDC59_RS01700 d1f11588295a74f53e31fba68027a24e 809 PRINTS PR00811 Bacterial general secretion pathway protein D signature 669 687 1.2E-29 T 29-03-2018 IPR001775 GspD/PilQ family CDC59_RS01700 d1f11588295a74f53e31fba68027a24e 809 PRINTS PR00811 Bacterial general secretion pathway protein D signature 569 579 1.2E-29 T 29-03-2018 IPR001775 GspD/PilQ family CDC59_RS01700 d1f11588295a74f53e31fba68027a24e 809 ProSitePatterns PS00875 Bacterial type II secretion system protein D signature. 650 683 - T 29-03-2018 IPR004845 Type II secretion system GspD, conserved site GO:0008565 CDC59_RS01700 d1f11588295a74f53e31fba68027a24e 809 Pfam PF03958 Bacterial type II/III secretion system short domain 217 297 3.4E-16 T 29-03-2018 IPR005644 NolW-like CDC59_RS01700 d1f11588295a74f53e31fba68027a24e 809 Pfam PF03958 Bacterial type II/III secretion system short domain 304 437 1.1E-16 T 29-03-2018 IPR005644 NolW-like CDC59_RS01700 d1f11588295a74f53e31fba68027a24e 809 Pfam PF03958 Bacterial type II/III secretion system short domain 154 214 1.7E-12 T 29-03-2018 IPR005644 NolW-like CDC59_RS09275 6fd43275d9cd0603673a1bb3f06fbf86 118 Gene3D G3DSA:3.10.20.280 1 89 3.4E-24 T 29-03-2018 IPR005346 RnfH protein CDC59_RS09275 6fd43275d9cd0603673a1bb3f06fbf86 118 SUPERFAMILY SSF54285 6 80 7.32E-15 T 29-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CDC59_RS09275 6fd43275d9cd0603673a1bb3f06fbf86 118 Hamap MF_00460 Protein RnfH [rnfH]. 7 96 19.001 T 29-03-2018 IPR005346 RnfH protein CDC59_RS09275 6fd43275d9cd0603673a1bb3f06fbf86 118 Pfam PF03658 RnfH family Ubiquitin 7 88 1.7E-21 T 29-03-2018 IPR005346 RnfH protein CDC59_RS10190 02f1d0be0090262800c88edcbe44287d 668 TIGRFAM TIGR03197 MnmC_Cterm: tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal domain 253 653 3.9E-128 T 29-03-2018 IPR017610 tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal GO:0008168|GO:0016645|GO:0055114 CDC59_RS10190 02f1d0be0090262800c88edcbe44287d 668 Gene3D G3DSA:3.50.50.60 243 659 2.2E-40 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS10190 02f1d0be0090262800c88edcbe44287d 668 Pfam PF01266 FAD dependent oxidoreductase 253 623 2.4E-41 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CDC59_RS10190 02f1d0be0090262800c88edcbe44287d 668 Gene3D G3DSA:3.40.50.150 10 242 1.6E-79 T 29-03-2018 CDC59_RS10190 02f1d0be0090262800c88edcbe44287d 668 Hamap MF_01102 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC [mnmC]. 8 648 24.953 T 29-03-2018 IPR023032 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC GO:0004808|GO:0008033|GO:0008168|GO:0016645|GO:0055114 CDC59_RS10190 02f1d0be0090262800c88edcbe44287d 668 Pfam PF05430 S-adenosyl-L-methionine-dependent methyltransferase 112 232 4.9E-44 T 29-03-2018 IPR008471 MnmC-like methyltransferase GO:0016645|GO:0055114 CDC59_RS10190 02f1d0be0090262800c88edcbe44287d 668 SUPERFAMILY SSF51905 252 468 2.4E-34 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS10190 02f1d0be0090262800c88edcbe44287d 668 SUPERFAMILY SSF51905 583 650 2.4E-34 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS03785 be4278d2bdab5c072b9c166f72651942 400 Gene3D G3DSA:3.40.630.10 6 267 4.2E-58 T 29-03-2018 CDC59_RS03785 be4278d2bdab5c072b9c166f72651942 400 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 13 376 3.8E-106 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CDC59_RS03785 be4278d2bdab5c072b9c166f72651942 400 Pfam PF01546 Peptidase family M20/M25/M40 72 385 3.7E-32 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CDC59_RS03785 be4278d2bdab5c072b9c166f72651942 400 PIRSF PIRSF005962 2 391 1.8E-123 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CDC59_RS03785 be4278d2bdab5c072b9c166f72651942 400 SUPERFAMILY SSF53187 8 197 8.86E-81 T 29-03-2018 CDC59_RS03785 be4278d2bdab5c072b9c166f72651942 400 SUPERFAMILY SSF53187 298 388 8.86E-81 T 29-03-2018 CDC59_RS03785 be4278d2bdab5c072b9c166f72651942 400 Gene3D G3DSA:3.40.630.10 268 392 9.8E-18 T 29-03-2018 CDC59_RS03785 be4278d2bdab5c072b9c166f72651942 400 SUPERFAMILY SSF55031 184 294 6.28E-27 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CDC59_RS14895 3a8da80ec8ad02f8456435306a4224c3 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 1.1E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS14895 3a8da80ec8ad02f8456435306a4224c3 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 1.1E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS14895 3a8da80ec8ad02f8456435306a4224c3 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.1E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS14895 3a8da80ec8ad02f8456435306a4224c3 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 1.1E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS14895 3a8da80ec8ad02f8456435306a4224c3 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.1E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS14895 3a8da80ec8ad02f8456435306a4224c3 266 SUPERFAMILY SSF51735 3 256 9.34E-60 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS14895 3a8da80ec8ad02f8456435306a4224c3 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 5.7E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS14895 3a8da80ec8ad02f8456435306a4224c3 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 5.7E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS14895 3a8da80ec8ad02f8456435306a4224c3 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 5.7E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS14895 3a8da80ec8ad02f8456435306a4224c3 266 Pfam PF00106 short chain dehydrogenase 4 199 2.6E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS14895 3a8da80ec8ad02f8456435306a4224c3 266 Gene3D G3DSA:3.40.50.720 2 261 4.6E-53 T 29-03-2018 CDC59_RS17870 54af60becc8389a016aa0b912c089f93 816 SMART SM00091 528 594 7.3E-6 T 29-03-2018 IPR000014 PAS domain CDC59_RS17870 54af60becc8389a016aa0b912c089f93 816 SMART SM00091 398 466 2.0 T 29-03-2018 IPR000014 PAS domain CDC59_RS17870 54af60becc8389a016aa0b912c089f93 816 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 648 813 1.5E-43 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS17870 54af60becc8389a016aa0b912c089f93 816 Gene3D G3DSA:3.30.450.20 169 291 2.9E-14 T 29-03-2018 CDC59_RS17870 54af60becc8389a016aa0b912c089f93 816 Gene3D G3DSA:3.30.450.20 380 530 9.7E-11 T 29-03-2018 CDC59_RS17870 54af60becc8389a016aa0b912c089f93 816 Gene3D G3DSA:3.30.450.20 531 662 5.6E-18 T 29-03-2018 CDC59_RS17870 54af60becc8389a016aa0b912c089f93 816 SUPERFAMILY SSF55785 515 637 7.2E-13 T 29-03-2018 IPR000014 PAS domain CDC59_RS17870 54af60becc8389a016aa0b912c089f93 816 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 535 646 1.4E-8 T 29-03-2018 IPR000014 PAS domain CDC59_RS17870 54af60becc8389a016aa0b912c089f93 816 SUPERFAMILY SSF55073 656 814 4.08E-44 T 29-03-2018 IPR029787 Nucleotide cyclase CDC59_RS17870 54af60becc8389a016aa0b912c089f93 816 Pfam PF02743 Cache domain 84 273 4.2E-14 T 29-03-2018 IPR033479 Double Cache domain 1 CDC59_RS17870 54af60becc8389a016aa0b912c089f93 816 SMART SM00267 640 816 4.7E-47 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS17870 54af60becc8389a016aa0b912c089f93 816 Gene3D G3DSA:3.30.450.20 50 168 1.4E-9 T 29-03-2018 CDC59_RS17870 54af60becc8389a016aa0b912c089f93 816 Pfam PF00989 PAS fold 533 633 2.1E-8 T 29-03-2018 IPR013767 PAS fold GO:0006355 CDC59_RS17870 54af60becc8389a016aa0b912c089f93 816 Gene3D G3DSA:3.30.70.270 663 815 8.8E-52 T 29-03-2018 CDC59_RS17870 54af60becc8389a016aa0b912c089f93 816 Pfam PF00990 Diguanylate cyclase, GGDEF domain 651 812 1.5E-40 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS17910 feced490d75bf8143d6a47c7363ce6d4 126 Pfam PF12582 Protein of unknown function (DUF3757) 12 126 1.4E-21 T 29-03-2018 IPR022231 Protein of unknown function DUF3757 CDC59_RS10980 97f7c5d5842617d9feeb7b9a7ea77ad4 632 SUPERFAMILY SSF56801 7 620 3.01E-158 T 29-03-2018 CDC59_RS10980 97f7c5d5842617d9feeb7b9a7ea77ad4 632 Gene3D G3DSA:3.30.300.30 498 611 1.0E-23 T 29-03-2018 CDC59_RS10980 97f7c5d5842617d9feeb7b9a7ea77ad4 632 ProSitePatterns PS00455 Putative AMP-binding domain signature. 240 251 - T 29-03-2018 IPR020845 AMP-binding, conserved site CDC59_RS10980 97f7c5d5842617d9feeb7b9a7ea77ad4 632 Pfam PF00501 AMP-binding enzyme 63 504 3.6E-85 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CDC59_RS10980 97f7c5d5842617d9feeb7b9a7ea77ad4 632 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 7 61 3.6E-22 T 29-03-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 CDC59_RS10980 97f7c5d5842617d9feeb7b9a7ea77ad4 632 Gene3D G3DSA:3.40.50.980 245 404 1.4E-37 T 29-03-2018 CDC59_RS10980 97f7c5d5842617d9feeb7b9a7ea77ad4 632 TIGRFAM TIGR02316 propion_prpE: propionate--CoA ligase 6 631 0.0 T 29-03-2018 IPR012694 Propionate--CoA ligase GO:0019629|GO:0050218 KEGG: 00640+6.2.1.17|MetaCyc: PWY-3941|MetaCyc: PWY-5104|MetaCyc: PWY-5747 CDC59_RS10980 97f7c5d5842617d9feeb7b9a7ea77ad4 632 Gene3D G3DSA:2.30.38.10 405 497 2.0E-10 T 29-03-2018 CDC59_RS10980 97f7c5d5842617d9feeb7b9a7ea77ad4 632 Pfam PF13193 AMP-binding enzyme C-terminal domain 513 596 1.2E-22 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CDC59_RS10980 97f7c5d5842617d9feeb7b9a7ea77ad4 632 Gene3D G3DSA:3.40.50.980 53 244 4.9E-44 T 29-03-2018 CDC59_RS08585 27415c426f41d1b036106eadb80eedbb 429 Gene3D G3DSA:1.10.287.470 149 193 1.6E-9 T 29-03-2018 CDC59_RS08585 27415c426f41d1b036106eadb80eedbb 429 SUPERFAMILY SSF56954 101 224 7.06E-6 T 29-03-2018 CDC59_RS08585 27415c426f41d1b036106eadb80eedbb 429 Gene3D G3DSA:2.40.50.100 219 415 8.1E-8 T 29-03-2018 CDC59_RS08585 27415c426f41d1b036106eadb80eedbb 429 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 70 300 1.1E-13 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CDC59_RS08585 27415c426f41d1b036106eadb80eedbb 429 Pfam PF00529 HlyD membrane-fusion protein of T1SS 187 357 1.1E-15 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 CDC59_RS08585 27415c426f41d1b036106eadb80eedbb 429 Gene3D G3DSA:2.40.50.100 72 148 7.4E-13 T 29-03-2018 CDC59_RS08585 27415c426f41d1b036106eadb80eedbb 429 SUPERFAMILY SSF111369 191 279 2.62E-6 T 29-03-2018 CDC59_RS04155 091275337e34fc2b792e47602c345747 233 Gene3D G3DSA:3.40.50.300 9 162 4.6E-7 T 29-03-2018 CDC59_RS04155 091275337e34fc2b792e47602c345747 233 TIGRFAM TIGR03420 DnaA_homol_Hda: DnaA regulatory inactivator Hda 6 230 2.8E-76 T 29-03-2018 IPR017788 DnaA regulatory inactivator Hda GO:0032297 CDC59_RS04155 091275337e34fc2b792e47602c345747 233 Gene3D G3DSA:1.10.8.60 165 231 2.3E-9 T 29-03-2018 CDC59_RS04155 091275337e34fc2b792e47602c345747 233 SUPERFAMILY SSF52540 16 210 7.03E-20 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS02190 261097e2cbb45f2e9caccd8d4a996a0a 263 PIRSF PIRSF012281 1 263 8.1E-124 T 29-03-2018 IPR012039 Uncharacterised conserved protein UCP012281 CDC59_RS02190 261097e2cbb45f2e9caccd8d4a996a0a 263 Pfam PF09906 Uncharacterized protein conserved in bacteria (DUF2135) 193 249 9.3E-15 T 29-03-2018 IPR019220 Domain of unknown function DUF2135 CDC59_RS08280 72546931492ac5412e618d076dc4dcec 429 SUPERFAMILY SSF51905 149 317 3.89E-30 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS08280 72546931492ac5412e618d076dc4dcec 429 Gene3D G3DSA:3.30.390.30 322 423 3.0E-21 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CDC59_RS08280 72546931492ac5412e618d076dc4dcec 429 SUPERFAMILY SSF51905 9 192 1.3E-42 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS08280 72546931492ac5412e618d076dc4dcec 429 Gene3D G3DSA:3.40.50.720 135 318 7.2E-35 T 29-03-2018 CDC59_RS08280 72546931492ac5412e618d076dc4dcec 429 SUPERFAMILY SSF55424 321 417 1.3E-17 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CDC59_RS08280 72546931492ac5412e618d076dc4dcec 429 Pfam PF14759 Reductase C-terminal 328 415 4.0E-19 T 29-03-2018 IPR028202 Reductase, C-terminal CDC59_RS08280 72546931492ac5412e618d076dc4dcec 429 Gene3D G3DSA:3.50.50.60 2 134 8.8E-16 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS08280 72546931492ac5412e618d076dc4dcec 429 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 150 168 7.5E-24 T 29-03-2018 CDC59_RS08280 72546931492ac5412e618d076dc4dcec 429 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 238 254 7.5E-24 T 29-03-2018 CDC59_RS08280 72546931492ac5412e618d076dc4dcec 429 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 105 123 7.5E-24 T 29-03-2018 CDC59_RS08280 72546931492ac5412e618d076dc4dcec 429 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 7.5E-24 T 29-03-2018 CDC59_RS08280 72546931492ac5412e618d076dc4dcec 429 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 263 285 7.5E-24 T 29-03-2018 CDC59_RS08280 72546931492ac5412e618d076dc4dcec 429 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 278 285 1.9E-16 T 29-03-2018 CDC59_RS08280 72546931492ac5412e618d076dc4dcec 429 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 239 253 1.9E-16 T 29-03-2018 CDC59_RS08280 72546931492ac5412e618d076dc4dcec 429 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 8 30 1.9E-16 T 29-03-2018 CDC59_RS08280 72546931492ac5412e618d076dc4dcec 429 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 150 175 1.9E-16 T 29-03-2018 CDC59_RS08280 72546931492ac5412e618d076dc4dcec 429 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 9 308 4.9E-60 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS02380 38f573c39140c21d6c12d7e3ffed6a84 608 ProSitePatterns PS00194 Thioredoxin family active site. 508 526 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CDC59_RS02380 38f573c39140c21d6c12d7e3ffed6a84 608 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 191 369 6.4E-21 T 29-03-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 CDC59_RS02380 38f573c39140c21d6c12d7e3ffed6a84 608 SUPERFAMILY SSF74863 31 148 6.54E-35 T 29-03-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain CDC59_RS02380 38f573c39140c21d6c12d7e3ffed6a84 608 Pfam PF11412 Disulphide bond corrector protein DsbC 33 148 4.5E-31 T 29-03-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain CDC59_RS02380 38f573c39140c21d6c12d7e3ffed6a84 608 Hamap MF_00399 Thiol:disulfide interchange protein DsbD [dsbD]. 9 599 36.935 T 29-03-2018 IPR022910 Thiol:disulphide interchange protein DsbD GO:0047134|GO:0055114 CDC59_RS02380 38f573c39140c21d6c12d7e3ffed6a84 608 Gene3D G3DSA:2.60.40.1250 28 156 1.4E-35 T 29-03-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain CDC59_RS02380 38f573c39140c21d6c12d7e3ffed6a84 608 Gene3D G3DSA:3.40.30.10 482 513 2.1E-4 T 29-03-2018 CDC59_RS02380 38f573c39140c21d6c12d7e3ffed6a84 608 Gene3D G3DSA:3.40.30.10 514 605 7.4E-13 T 29-03-2018 CDC59_RS02380 38f573c39140c21d6c12d7e3ffed6a84 608 SUPERFAMILY SSF52833 494 596 2.84E-20 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS02380 38f573c39140c21d6c12d7e3ffed6a84 608 Pfam PF13899 Thioredoxin-like 491 573 2.5E-14 T 29-03-2018 CDC59_RS02540 3f32f74a89aa5f3b44eeae4ac85f6af1 211 PIRSF PIRSF004649 1 210 2.0E-44 T 29-03-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC CDC59_RS02540 3f32f74a89aa5f3b44eeae4ac85f6af1 211 Pfam PF05494 MlaC protein 37 199 2.8E-50 T 29-03-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC CDC59_RS02540 3f32f74a89aa5f3b44eeae4ac85f6af1 211 Gene3D G3DSA:1.10.10.640 166 211 6.2E-8 T 29-03-2018 CDC59_RS02540 3f32f74a89aa5f3b44eeae4ac85f6af1 211 Gene3D G3DSA:3.10.450.50 30 77 0.061 T 29-03-2018 CDC59_RS02540 3f32f74a89aa5f3b44eeae4ac85f6af1 211 Gene3D G3DSA:3.10.450.50 78 165 1.5E-29 T 29-03-2018 CDC59_RS06935 084b0665db6ddf5601f0556fc93dc4c8 282 Pfam PF01464 Transglycosylase SLT domain 109 214 3.1E-29 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 CDC59_RS06935 084b0665db6ddf5601f0556fc93dc4c8 282 SUPERFAMILY SSF53955 101 238 1.75E-45 T 29-03-2018 IPR023346 Lysozyme-like domain CDC59_RS06935 084b0665db6ddf5601f0556fc93dc4c8 282 Gene3D G3DSA:1.10.530.10 69 242 6.7E-46 T 29-03-2018 CDC59_RS06935 084b0665db6ddf5601f0556fc93dc4c8 282 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 127 155 - T 29-03-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 CDC59_RS06105 cd370cf011ec2a3d46fc90a25fd008a2 324 SUPERFAMILY SSF103481 198 295 2.22E-12 T 29-03-2018 CDC59_RS06105 cd370cf011ec2a3d46fc90a25fd008a2 324 Pfam PF00892 EamA-like transporter family 164 293 2.6E-6 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CDC59_RS06105 cd370cf011ec2a3d46fc90a25fd008a2 324 Pfam PF00892 EamA-like transporter family 21 150 8.3E-7 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CDC59_RS05085 012d18f5f03153f1735d3c36d89ee4a4 302 SUPERFAMILY SSF46785 1 109 1.02E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS05085 012d18f5f03153f1735d3c36d89ee4a4 302 Gene3D G3DSA:3.40.190.10 178 259 1.9E-17 T 29-03-2018 CDC59_RS05085 012d18f5f03153f1735d3c36d89ee4a4 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 1.4E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS05085 012d18f5f03153f1735d3c36d89ee4a4 302 SUPERFAMILY SSF53850 86 290 2.34E-34 T 29-03-2018 CDC59_RS05085 012d18f5f03153f1735d3c36d89ee4a4 302 Gene3D G3DSA:1.10.10.10 1 83 1.9E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS05085 012d18f5f03153f1735d3c36d89ee4a4 302 Gene3D G3DSA:3.40.190.10 89 177 1.8E-16 T 29-03-2018 CDC59_RS05085 012d18f5f03153f1735d3c36d89ee4a4 302 Pfam PF03466 LysR substrate binding domain 85 287 5.3E-39 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS05085 012d18f5f03153f1735d3c36d89ee4a4 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.1E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS05085 012d18f5f03153f1735d3c36d89ee4a4 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.1E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS05085 012d18f5f03153f1735d3c36d89ee4a4 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.1E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS02200 1b730456887bd895fc1e082e268b1969 196 Gene3D G3DSA:3.40.50.150 1 188 1.1E-24 T 29-03-2018 CDC59_RS02200 1b730456887bd895fc1e082e268b1969 196 SUPERFAMILY SSF53335 1 152 2.66E-26 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS02200 1b730456887bd895fc1e082e268b1969 196 Pfam PF08241 Methyltransferase domain 44 137 1.5E-13 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CDC59_RS14575 c463f5b04123346d3a2957d4ecd07a0c 87 Pfam PF04380 Membrane fusogenic activity 1 75 5.4E-30 T 29-03-2018 IPR007475 Membrane fusogenic activity CDC59_RS02695 8019be290da8a664509f1c3eeb8ca2ff 467 PIRSF PIRSF038885 4 466 4.9E-149 T 29-03-2018 IPR030689 Cytochrome b GO:0006122|GO:0008121|GO:0009055|GO:0045275 Reactome: R-HSA-611105 CDC59_RS02695 8019be290da8a664509f1c3eeb8ca2ff 467 Gene3D G3DSA:1.20.810.10 15 458 1.3E-160 T 29-03-2018 IPR027387 Cytochrome b/b6-like domain Reactome: R-HSA-611105 CDC59_RS02695 8019be290da8a664509f1c3eeb8ca2ff 467 Pfam PF00033 Cytochrome b/b6/petB 31 226 3.2E-63 T 29-03-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 CDC59_RS02695 8019be290da8a664509f1c3eeb8ca2ff 467 SUPERFAMILY SSF81648 296 317 4.39E-22 T 29-03-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 CDC59_RS02695 8019be290da8a664509f1c3eeb8ca2ff 467 SUPERFAMILY SSF81648 364 454 4.39E-22 T 29-03-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 CDC59_RS02695 8019be290da8a664509f1c3eeb8ca2ff 467 SUPERFAMILY SSF81342 16 294 5.18E-95 T 29-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 CDC59_RS02695 8019be290da8a664509f1c3eeb8ca2ff 467 Pfam PF00032 Cytochrome b(C-terminal)/b6/petD 292 440 6.0E-41 T 29-03-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 CDC59_RS08980 3bf712fd09bc8a663105ec941f0538d2 375 Pfam PF00842 Alanine racemase, C-terminal domain 232 357 5.0E-40 T 29-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CDC59_RS08980 3bf712fd09bc8a663105ec941f0538d2 375 Gene3D G3DSA:3.20.20.10 6 201 6.0E-38 T 29-03-2018 IPR029066 PLP-binding barrel CDC59_RS08980 3bf712fd09bc8a663105ec941f0538d2 375 Gene3D G3DSA:2.40.37.10 202 367 3.3E-58 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CDC59_RS08980 3bf712fd09bc8a663105ec941f0538d2 375 Hamap MF_01201 Alanine racemase. 2 360 33.494 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CDC59_RS08980 3bf712fd09bc8a663105ec941f0538d2 375 TIGRFAM TIGR00492 alr: alanine racemase 4 357 1.6E-108 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CDC59_RS08980 3bf712fd09bc8a663105ec941f0538d2 375 SUPERFAMILY SSF51419 9 233 1.44E-62 T 29-03-2018 IPR029066 PLP-binding barrel CDC59_RS08980 3bf712fd09bc8a663105ec941f0538d2 375 SUPERFAMILY SSF50621 227 358 7.67E-43 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CDC59_RS08980 3bf712fd09bc8a663105ec941f0538d2 375 Pfam PF01168 Alanine racemase, N-terminal domain 10 217 1.7E-68 T 29-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CDC59_RS08980 3bf712fd09bc8a663105ec941f0538d2 375 PRINTS PR00992 Alanine racemase signature 155 166 1.7E-59 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CDC59_RS08980 3bf712fd09bc8a663105ec941f0538d2 375 PRINTS PR00992 Alanine racemase signature 61 79 1.7E-59 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CDC59_RS08980 3bf712fd09bc8a663105ec941f0538d2 375 PRINTS PR00992 Alanine racemase signature 27 43 1.7E-59 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CDC59_RS08980 3bf712fd09bc8a663105ec941f0538d2 375 PRINTS PR00992 Alanine racemase signature 248 263 1.7E-59 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CDC59_RS08980 3bf712fd09bc8a663105ec941f0538d2 375 PRINTS PR00992 Alanine racemase signature 265 280 1.7E-59 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CDC59_RS08980 3bf712fd09bc8a663105ec941f0538d2 375 PRINTS PR00992 Alanine racemase signature 121 133 1.7E-59 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CDC59_RS08980 3bf712fd09bc8a663105ec941f0538d2 375 PRINTS PR00992 Alanine racemase signature 342 355 1.7E-59 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CDC59_RS08980 3bf712fd09bc8a663105ec941f0538d2 375 PRINTS PR00992 Alanine racemase signature 190 217 1.7E-59 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CDC59_RS08980 3bf712fd09bc8a663105ec941f0538d2 375 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 32 42 - T 29-03-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CDC59_RS08980 3bf712fd09bc8a663105ec941f0538d2 375 SMART SM01005 232 360 1.7E-65 T 29-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CDC59_RS09535 e95621b397377359313049769464afd6 242 Pfam PF00881 Nitroreductase family 18 220 3.5E-27 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CDC59_RS09535 e95621b397377359313049769464afd6 242 SUPERFAMILY SSF55469 15 93 6.67E-42 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CDC59_RS09535 e95621b397377359313049769464afd6 242 SUPERFAMILY SSF55469 159 240 6.67E-42 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CDC59_RS09535 e95621b397377359313049769464afd6 242 Gene3D G3DSA:3.40.109.10 1 239 1.1E-43 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CDC59_RS04515 a9f85d783004b5744c419055b19eb398 332 Gene3D G3DSA:3.40.50.2000 1 167 1.6E-37 T 29-03-2018 CDC59_RS04515 a9f85d783004b5744c419055b19eb398 332 SUPERFAMILY SSF53756 1 317 1.73E-66 T 29-03-2018 CDC59_RS04515 a9f85d783004b5744c419055b19eb398 332 Gene3D G3DSA:3.40.50.2000 178 329 5.3E-28 T 29-03-2018 CDC59_RS04515 a9f85d783004b5744c419055b19eb398 332 TIGRFAM TIGR02193 heptsyl_trn_I: lipopolysaccharide heptosyltransferase I 2 329 8.1E-123 T 29-03-2018 IPR011908 Lipopolysaccharide heptosyltransferase I GO:0008920|GO:0009244 CDC59_RS04515 a9f85d783004b5744c419055b19eb398 332 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 76 315 6.5E-44 T 29-03-2018 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 CDC59_RS16150 72f3499ce31fdbfd48a4aa839187bd37 499 PRINTS PR00695 Copper containing nitrite reductase signature 93 109 9.1E-27 T 29-03-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 CDC59_RS16150 72f3499ce31fdbfd48a4aa839187bd37 499 PRINTS PR00695 Copper containing nitrite reductase signature 111 128 9.1E-27 T 29-03-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 CDC59_RS16150 72f3499ce31fdbfd48a4aa839187bd37 499 PRINTS PR00695 Copper containing nitrite reductase signature 153 168 9.1E-27 T 29-03-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 CDC59_RS16150 72f3499ce31fdbfd48a4aa839187bd37 499 PRINTS PR00695 Copper containing nitrite reductase signature 170 186 9.1E-27 T 29-03-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 CDC59_RS16150 72f3499ce31fdbfd48a4aa839187bd37 499 PRINTS PR00695 Copper containing nitrite reductase signature 67 85 9.1E-27 T 29-03-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 CDC59_RS16150 72f3499ce31fdbfd48a4aa839187bd37 499 PRINTS PR00695 Copper containing nitrite reductase signature 128 147 9.1E-27 T 29-03-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 CDC59_RS16150 72f3499ce31fdbfd48a4aa839187bd37 499 TIGRFAM TIGR02376 Cu_nitrite_red: nitrite reductase, copper-containing 48 344 3.6E-110 T 29-03-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 CDC59_RS16150 72f3499ce31fdbfd48a4aa839187bd37 499 Gene3D G3DSA:2.60.40.420 191 362 1.8E-24 T 29-03-2018 IPR008972 Cupredoxin CDC59_RS16150 72f3499ce31fdbfd48a4aa839187bd37 499 SUPERFAMILY SSF49503 189 348 2.9E-52 T 29-03-2018 IPR008972 Cupredoxin CDC59_RS16150 72f3499ce31fdbfd48a4aa839187bd37 499 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 383 467 1.3E-9 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS16150 72f3499ce31fdbfd48a4aa839187bd37 499 Pfam PF07732 Multicopper oxidase 78 189 2.4E-11 T 29-03-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 CDC59_RS16150 72f3499ce31fdbfd48a4aa839187bd37 499 SUPERFAMILY SSF46626 386 489 1.39E-20 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS16150 72f3499ce31fdbfd48a4aa839187bd37 499 Gene3D G3DSA:2.60.40.420 33 190 1.6E-31 T 29-03-2018 IPR008972 Cupredoxin CDC59_RS16150 72f3499ce31fdbfd48a4aa839187bd37 499 SUPERFAMILY SSF49503 51 205 8.44E-42 T 29-03-2018 IPR008972 Cupredoxin CDC59_RS16150 72f3499ce31fdbfd48a4aa839187bd37 499 Gene3D G3DSA:1.10.760.10 364 499 1.0E-25 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS16175 eaea219c879a3252e283fe73ed0e49c7 785 SUPERFAMILY SSF51395 397 752 4.45E-113 T 29-03-2018 CDC59_RS16175 eaea219c879a3252e283fe73ed0e49c7 785 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 402 731 1.2E-61 T 29-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CDC59_RS16175 eaea219c879a3252e283fe73ed0e49c7 785 SUPERFAMILY SSF51905 1 149 1.4E-39 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS16175 eaea219c879a3252e283fe73ed0e49c7 785 SUPERFAMILY SSF51905 251 346 1.4E-39 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS16175 eaea219c879a3252e283fe73ed0e49c7 785 Pfam PF01494 FAD binding domain 3 305 2.5E-8 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 CDC59_RS16175 eaea219c879a3252e283fe73ed0e49c7 785 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 128 143 6.2E-10 T 29-03-2018 CDC59_RS16175 eaea219c879a3252e283fe73ed0e49c7 785 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 268 283 6.2E-10 T 29-03-2018 CDC59_RS16175 eaea219c879a3252e283fe73ed0e49c7 785 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 283 299 6.2E-10 T 29-03-2018 CDC59_RS16175 eaea219c879a3252e283fe73ed0e49c7 785 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 6.2E-10 T 29-03-2018 CDC59_RS16175 eaea219c879a3252e283fe73ed0e49c7 785 Gene3D G3DSA:3.50.50.60 1 382 1.7E-34 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS16175 eaea219c879a3252e283fe73ed0e49c7 785 Gene3D G3DSA:3.20.20.70 389 758 1.5E-110 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS15430 1dc1d82d89ee11cee3c5a5248e3a4fb6 303 SUPERFAMILY SSF117892 101 219 2.22E-9 T 29-03-2018 IPR001107 Band 7 domain CDC59_RS15430 1dc1d82d89ee11cee3c5a5248e3a4fb6 303 Pfam PF01145 SPFH domain / Band 7 family 37 235 1.2E-30 T 29-03-2018 IPR001107 Band 7 domain CDC59_RS09870 7b90924f2ec46fe97b2b4fd60d2a9e37 355 Pfam PF00005 ABC transporter 28 175 9.5E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS09870 7b90924f2ec46fe97b2b4fd60d2a9e37 355 Pfam PF08402 TOBE domain 284 351 2.3E-8 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CDC59_RS09870 7b90924f2ec46fe97b2b4fd60d2a9e37 355 SUPERFAMILY SSF52540 13 254 2.13E-80 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS09870 7b90924f2ec46fe97b2b4fd60d2a9e37 355 SUPERFAMILY SSF50331 251 353 6.38E-13 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CDC59_RS09870 7b90924f2ec46fe97b2b4fd60d2a9e37 355 Gene3D G3DSA:2.40.50.140 285 346 2.2E-7 T 29-03-2018 CDC59_RS09870 7b90924f2ec46fe97b2b4fd60d2a9e37 355 Gene3D G3DSA:3.40.50.300 10 260 5.4E-70 T 29-03-2018 CDC59_RS09870 7b90924f2ec46fe97b2b4fd60d2a9e37 355 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS09870 7b90924f2ec46fe97b2b4fd60d2a9e37 355 SMART SM00382 37 225 3.1E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS01465 097a6f90bb6e72edb4cdb364f0d42a6b 137 Gene3D G3DSA:1.10.10.10 7 136 6.1E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS01465 097a6f90bb6e72edb4cdb364f0d42a6b 137 SUPERFAMILY SSF46785 22 123 1.28E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS01465 097a6f90bb6e72edb4cdb364f0d42a6b 137 Pfam PF01638 HxlR-like helix-turn-helix 37 123 1.3E-27 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type CDC59_RS21890 6d6ecfad26754e30485a29309414d5ca 1048 SUPERFAMILY SSF82714 710 792 5.1E-18 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS21890 6d6ecfad26754e30485a29309414d5ca 1048 SUPERFAMILY SSF82693 667 706 1.88E-10 T 29-03-2018 CDC59_RS21890 6d6ecfad26754e30485a29309414d5ca 1048 SUPERFAMILY SSF82693 793 842 1.88E-10 T 29-03-2018 CDC59_RS21890 6d6ecfad26754e30485a29309414d5ca 1048 Gene3D G3DSA:1.20.1640.10 806 1027 1.4E-32 T 29-03-2018 CDC59_RS21890 6d6ecfad26754e30485a29309414d5ca 1048 Gene3D G3DSA:1.20.1640.10 281 501 5.1E-47 T 29-03-2018 CDC59_RS21890 6d6ecfad26754e30485a29309414d5ca 1048 SUPERFAMILY SSF82866 816 1013 2.09E-42 T 29-03-2018 CDC59_RS21890 6d6ecfad26754e30485a29309414d5ca 1048 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 6.6E-80 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS21890 6d6ecfad26754e30485a29309414d5ca 1048 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 6.6E-80 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS21890 6d6ecfad26754e30485a29309414d5ca 1048 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 6.6E-80 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS21890 6d6ecfad26754e30485a29309414d5ca 1048 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 6.6E-80 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS21890 6d6ecfad26754e30485a29309414d5ca 1048 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 6.6E-80 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS21890 6d6ecfad26754e30485a29309414d5ca 1048 PRINTS PR00702 Acriflavin resistance protein family signature 610 624 6.6E-80 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS21890 6d6ecfad26754e30485a29309414d5ca 1048 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 6.6E-80 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS21890 6d6ecfad26754e30485a29309414d5ca 1048 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 6.6E-80 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS21890 6d6ecfad26754e30485a29309414d5ca 1048 PRINTS PR00702 Acriflavin resistance protein family signature 543 560 6.6E-80 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS21890 6d6ecfad26754e30485a29309414d5ca 1048 SUPERFAMILY SSF82693 136 182 5.23E-22 T 29-03-2018 CDC59_RS21890 6d6ecfad26754e30485a29309414d5ca 1048 SUPERFAMILY SSF82693 268 324 5.23E-22 T 29-03-2018 CDC59_RS21890 6d6ecfad26754e30485a29309414d5ca 1048 Gene3D G3DSA:3.30.70.1430 559 657 6.1E-14 T 29-03-2018 CDC59_RS21890 6d6ecfad26754e30485a29309414d5ca 1048 SUPERFAMILY SSF82693 40 133 3.35E-23 T 29-03-2018 CDC59_RS21890 6d6ecfad26754e30485a29309414d5ca 1048 Gene3D G3DSA:3.30.70.1430 40 142 2.8E-24 T 29-03-2018 CDC59_RS21890 6d6ecfad26754e30485a29309414d5ca 1048 SUPERFAMILY SSF82714 183 266 2.09E-15 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS21890 6d6ecfad26754e30485a29309414d5ca 1048 Pfam PF00873 AcrB/AcrD/AcrF family 4 1013 0.0 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS21890 6d6ecfad26754e30485a29309414d5ca 1048 SUPERFAMILY SSF82693 556 653 9.68E-16 T 29-03-2018 CDC59_RS21890 6d6ecfad26754e30485a29309414d5ca 1048 Gene3D G3DSA:3.30.2090.10 181 269 1.6E-13 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS21890 6d6ecfad26754e30485a29309414d5ca 1048 Gene3D G3DSA:3.30.2090.10 708 795 2.2E-19 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS21890 6d6ecfad26754e30485a29309414d5ca 1048 SUPERFAMILY SSF82866 290 491 1.18E-47 T 29-03-2018 CDC59_RS12935 2c7099daadcb3371b1cd9c958b5e5635 62 SUPERFAMILY SSF158997 1 52 3.66E-21 T 29-03-2018 CDC59_RS12935 2c7099daadcb3371b1cd9c958b5e5635 62 Hamap MF_01187 UPF0434 protein YcaR [ycaR]. 1 54 27.259 T 29-03-2018 IPR005651 Uncharacterised protein family UPF0434/Trm112 CDC59_RS12935 2c7099daadcb3371b1cd9c958b5e5635 62 Pfam PF03966 Trm112p-like protein 2 41 2.4E-11 T 29-03-2018 IPR005651 Uncharacterised protein family UPF0434/Trm112 CDC59_RS12935 2c7099daadcb3371b1cd9c958b5e5635 62 Gene3D G3DSA:2.20.25.10 8 53 1.0E-20 T 29-03-2018 CDC59_RS23185 3d6297c10309faad923490c64a220c76 364 Gene3D G3DSA:2.40.160.10 8 364 2.7E-68 T 29-03-2018 CDC59_RS23185 3d6297c10309faad923490c64a220c76 364 Pfam PF13609 Gram-negative porin 7 332 6.8E-49 T 29-03-2018 CDC59_RS23185 3d6297c10309faad923490c64a220c76 364 SUPERFAMILY SSF56935 22 364 1.06E-79 T 29-03-2018 CDC59_RS08820 b2234199b118b15ddd59a2f2c7ad1f87 337 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 44 324 4.7E-69 T 29-03-2018 IPR010067 Aliphatic sulfonates-binding protein GO:0016020|GO:0042626 CDC59_RS08820 b2234199b118b15ddd59a2f2c7ad1f87 337 SUPERFAMILY SSF53850 42 278 2.58E-50 T 29-03-2018 CDC59_RS08820 b2234199b118b15ddd59a2f2c7ad1f87 337 SMART SM00062 43 266 1.3E-22 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CDC59_RS08820 b2234199b118b15ddd59a2f2c7ad1f87 337 Gene3D G3DSA:3.40.190.10 147 330 4.1E-33 T 29-03-2018 CDC59_RS08820 b2234199b118b15ddd59a2f2c7ad1f87 337 Gene3D G3DSA:3.40.190.10 39 146 9.1E-18 T 29-03-2018 CDC59_RS08820 b2234199b118b15ddd59a2f2c7ad1f87 337 Pfam PF09084 NMT1/THI5 like 68 262 5.3E-13 T 29-03-2018 IPR015168 SsuA/THI5-like CDC59_RS18605 01d0e0d28d2335be0c4ddfb1d87b96eb 145 SUPERFAMILY SSF54909 68 144 3.54E-15 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CDC59_RS18605 01d0e0d28d2335be0c4ddfb1d87b96eb 145 Gene3D G3DSA:1.10.10.10 1 49 1.2E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS18605 01d0e0d28d2335be0c4ddfb1d87b96eb 145 Pfam PF13412 Winged helix-turn-helix DNA-binding 6 52 1.3E-11 T 29-03-2018 CDC59_RS18605 01d0e0d28d2335be0c4ddfb1d87b96eb 145 SUPERFAMILY SSF46785 6 61 9.25E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS18605 01d0e0d28d2335be0c4ddfb1d87b96eb 145 Gene3D G3DSA:3.30.70.920 50 139 8.6E-22 T 29-03-2018 CDC59_RS18605 01d0e0d28d2335be0c4ddfb1d87b96eb 145 SMART SM00344 6 112 2.7E-22 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CDC59_RS18605 01d0e0d28d2335be0c4ddfb1d87b96eb 145 Pfam PF01037 Lrp/AsnC ligand binding domain 74 142 4.1E-14 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CDC59_RS18605 01d0e0d28d2335be0c4ddfb1d87b96eb 145 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 6 22 1.1E-10 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CDC59_RS18605 01d0e0d28d2335be0c4ddfb1d87b96eb 145 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 33 52 1.1E-10 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CDC59_RS18605 01d0e0d28d2335be0c4ddfb1d87b96eb 145 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 22 33 1.1E-10 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CDC59_RS15440 27669cc14735709e42de6a201176e140 177 Gene3D G3DSA:3.30.530.20 14 176 5.5E-17 T 29-03-2018 IPR023393 START-like domain CDC59_RS15440 27669cc14735709e42de6a201176e140 177 SUPERFAMILY SSF55961 30 167 1.0E-13 T 29-03-2018 CDC59_RS10480 0a3145aad464327a4f94ff8ee5d4dfca 596 PIRSF PIRSF000350 19 590 1.6E-79 T 29-03-2018 CDC59_RS10480 0a3145aad464327a4f94ff8ee5d4dfca 596 Gene3D G3DSA:2.40.50.100 4 64 3.5E-13 T 29-03-2018 CDC59_RS10480 0a3145aad464327a4f94ff8ee5d4dfca 596 Pfam PF00364 Biotin-requiring enzyme 5 75 9.4E-19 T 29-03-2018 IPR000089 Biotin/lipoyl attachment CDC59_RS10480 0a3145aad464327a4f94ff8ee5d4dfca 596 Gene3D G3DSA:3.30.390.30 463 586 1.9E-36 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CDC59_RS10480 0a3145aad464327a4f94ff8ee5d4dfca 596 Gene3D G3DSA:1.10.287.990 155 223 1.0E-21 T 29-03-2018 CDC59_RS10480 0a3145aad464327a4f94ff8ee5d4dfca 596 Gene3D G3DSA:3.50.50.60 364 462 9.8E-18 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS10480 0a3145aad464327a4f94ff8ee5d4dfca 596 Gene3D G3DSA:3.50.50.60 243 363 2.8E-22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS10480 0a3145aad464327a4f94ff8ee5d4dfca 596 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 471 579 3.7E-32 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CDC59_RS10480 0a3145aad464327a4f94ff8ee5d4dfca 596 SUPERFAMILY SSF55424 467 588 2.41E-37 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CDC59_RS10480 0a3145aad464327a4f94ff8ee5d4dfca 596 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 417 439 6.3E-39 T 29-03-2018 CDC59_RS10480 0a3145aad464327a4f94ff8ee5d4dfca 596 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 262 280 6.3E-39 T 29-03-2018 CDC59_RS10480 0a3145aad464327a4f94ff8ee5d4dfca 596 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 300 318 6.3E-39 T 29-03-2018 CDC59_RS10480 0a3145aad464327a4f94ff8ee5d4dfca 596 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 388 404 6.3E-39 T 29-03-2018 CDC59_RS10480 0a3145aad464327a4f94ff8ee5d4dfca 596 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 125 144 6.3E-39 T 29-03-2018 CDC59_RS10480 0a3145aad464327a4f94ff8ee5d4dfca 596 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 158 168 - T 29-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CDC59_RS10480 0a3145aad464327a4f94ff8ee5d4dfca 596 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 123 581 1.4E-141 T 29-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CDC59_RS10480 0a3145aad464327a4f94ff8ee5d4dfca 596 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CDC59_RS10480 0a3145aad464327a4f94ff8ee5d4dfca 596 SUPERFAMILY SSF51230 2 94 1.57E-22 T 29-03-2018 IPR011053 Single hybrid motif CDC59_RS10480 0a3145aad464327a4f94ff8ee5d4dfca 596 Gene3D G3DSA:3.90.1170.30 65 99 0.0052 T 29-03-2018 CDC59_RS10480 0a3145aad464327a4f94ff8ee5d4dfca 596 SUPERFAMILY SSF51905 120 461 8.1E-51 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS10480 0a3145aad464327a4f94ff8ee5d4dfca 596 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 467 488 1.2E-68 T 29-03-2018 CDC59_RS10480 0a3145aad464327a4f94ff8ee5d4dfca 596 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 300 325 1.2E-68 T 29-03-2018 CDC59_RS10480 0a3145aad464327a4f94ff8ee5d4dfca 596 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 432 439 1.2E-68 T 29-03-2018 CDC59_RS10480 0a3145aad464327a4f94ff8ee5d4dfca 596 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 157 172 1.2E-68 T 29-03-2018 CDC59_RS10480 0a3145aad464327a4f94ff8ee5d4dfca 596 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 265 274 1.2E-68 T 29-03-2018 CDC59_RS10480 0a3145aad464327a4f94ff8ee5d4dfca 596 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 554 574 1.2E-68 T 29-03-2018 CDC59_RS10480 0a3145aad464327a4f94ff8ee5d4dfca 596 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 124 146 1.2E-68 T 29-03-2018 CDC59_RS10480 0a3145aad464327a4f94ff8ee5d4dfca 596 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 389 403 1.2E-68 T 29-03-2018 CDC59_RS10480 0a3145aad464327a4f94ff8ee5d4dfca 596 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 532 547 1.2E-68 T 29-03-2018 CDC59_RS10480 0a3145aad464327a4f94ff8ee5d4dfca 596 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 124 452 2.2E-55 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS12680 edd63b42cb81eefe38f7c1f77b3b2730 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 3.1E-30 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CDC59_RS12680 edd63b42cb81eefe38f7c1f77b3b2730 67 SMART SM00357 3 67 5.2E-29 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 CDC59_RS12680 edd63b42cb81eefe38f7c1f77b3b2730 67 SUPERFAMILY SSF50249 1 65 1.18E-25 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDC59_RS12680 edd63b42cb81eefe38f7c1f77b3b2730 67 PIRSF PIRSF002599 1 67 1.2E-23 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 CDC59_RS12680 edd63b42cb81eefe38f7c1f77b3b2730 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 29-03-2018 IPR019844 Cold-shock conserved site CDC59_RS12680 edd63b42cb81eefe38f7c1f77b3b2730 67 PRINTS PR00050 Cold shock protein signature 40 58 1.6E-16 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CDC59_RS12680 edd63b42cb81eefe38f7c1f77b3b2730 67 PRINTS PR00050 Cold shock protein signature 4 19 1.6E-16 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CDC59_RS12680 edd63b42cb81eefe38f7c1f77b3b2730 67 PRINTS PR00050 Cold shock protein signature 25 34 1.6E-16 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CDC59_RS12680 edd63b42cb81eefe38f7c1f77b3b2730 67 Gene3D G3DSA:2.40.50.140 1 66 5.2E-30 T 29-03-2018 CDC59_RS04650 64392d0c8f85a4ed553238743671b263 186 Pfam PF12019 Type II transport protein GspH 46 167 8.3E-9 T 29-03-2018 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 CDC59_RS04650 64392d0c8f85a4ed553238743671b263 186 Pfam PF07963 Prokaryotic N-terminal methylation motif 6 30 4.9E-5 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS04650 64392d0c8f85a4ed553238743671b263 186 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 7 30 2.7E-5 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS04650 64392d0c8f85a4ed553238743671b263 186 Gene3D G3DSA:3.30.700.10 11 179 1.4E-9 T 29-03-2018 CDC59_RS04650 64392d0c8f85a4ed553238743671b263 186 SUPERFAMILY SSF54523 11 112 7.85E-11 T 29-03-2018 CDC59_RS03025 a22e9120fed65336c067a9a6f08d7436 401 Gene3D G3DSA:3.30.70.360 190 292 2.7E-23 T 29-03-2018 CDC59_RS03025 a22e9120fed65336c067a9a6f08d7436 401 SUPERFAMILY SSF55031 186 292 1.2E-22 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CDC59_RS03025 a22e9120fed65336c067a9a6f08d7436 401 Gene3D G3DSA:3.40.630.10 293 395 5.7E-10 T 29-03-2018 CDC59_RS03025 a22e9120fed65336c067a9a6f08d7436 401 SUPERFAMILY SSF53187 12 185 6.86E-59 T 29-03-2018 CDC59_RS03025 a22e9120fed65336c067a9a6f08d7436 401 SUPERFAMILY SSF53187 316 394 6.86E-59 T 29-03-2018 CDC59_RS03025 a22e9120fed65336c067a9a6f08d7436 401 Pfam PF01546 Peptidase family M20/M25/M40 79 393 2.2E-34 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CDC59_RS03025 a22e9120fed65336c067a9a6f08d7436 401 Pfam PF07687 Peptidase dimerisation domain 182 292 1.8E-22 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CDC59_RS03025 a22e9120fed65336c067a9a6f08d7436 401 Gene3D G3DSA:3.40.630.10 6 189 5.2E-30 T 29-03-2018 CDC59_RS03025 a22e9120fed65336c067a9a6f08d7436 401 TIGRFAM TIGR01892 AcOrn-deacetyl: acetylornithine deacetylase (ArgE) 20 391 9.7E-117 T 29-03-2018 IPR010169 Acetylornithine deacetylase ArgE GO:0005737|GO:0006526|GO:0008777 KEGG: 00220+3.5.1.16|MetaCyc: PWY-5154 CDC59_RS20055 75132dff79c938fa08a873d99b7cc374 483 Gene3D G3DSA:3.20.140.10 8 443 5.8E-84 T 29-03-2018 CDC59_RS20055 75132dff79c938fa08a873d99b7cc374 483 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 179 425 2.9E-64 T 29-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 CDC59_RS20055 75132dff79c938fa08a873d99b7cc374 483 SUPERFAMILY SSF51690 148 474 2.35E-47 T 29-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CDC59_RS20055 75132dff79c938fa08a873d99b7cc374 483 PIRSF PIRSF005943 8 480 1.8E-196 T 29-03-2018 IPR016471 Nicotinamide phosphoribosyl transferase Reactome: R-HSA-1368108|Reactome: R-HSA-197264 CDC59_RS04380 4ecbdd574fc0f928adb343e3f4b39861 304 PRINTS PR00146 Dihydrodipicolinate synthase signature 121 137 1.3E-13 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CDC59_RS04380 4ecbdd574fc0f928adb343e3f4b39861 304 PRINTS PR00146 Dihydrodipicolinate synthase signature 54 75 1.3E-13 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CDC59_RS04380 4ecbdd574fc0f928adb343e3f4b39861 304 PRINTS PR00146 Dihydrodipicolinate synthase signature 146 163 1.3E-13 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CDC59_RS04380 4ecbdd574fc0f928adb343e3f4b39861 304 Gene3D G3DSA:3.20.20.70 13 304 1.5E-72 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS04380 4ecbdd574fc0f928adb343e3f4b39861 304 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 151 181 - T 29-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 CDC59_RS04380 4ecbdd574fc0f928adb343e3f4b39861 304 Pfam PF00701 Dihydrodipicolinate synthetase family 20 291 1.3E-46 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CDC59_RS04380 4ecbdd574fc0f928adb343e3f4b39861 304 PIRSF PIRSF001365 16 304 8.1E-67 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CDC59_RS04380 4ecbdd574fc0f928adb343e3f4b39861 304 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 18 303 41.895 T 29-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CDC59_RS04380 4ecbdd574fc0f928adb343e3f4b39861 304 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 24 291 8.0E-62 T 29-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CDC59_RS04380 4ecbdd574fc0f928adb343e3f4b39861 304 SMART SM01130 18 304 5.5E-84 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CDC59_RS04380 4ecbdd574fc0f928adb343e3f4b39861 304 SUPERFAMILY SSF51569 18 301 2.41E-74 T 29-03-2018 CDC59_RS02365 dd8b880d7708ece1010b6bed1e9a1c50 326 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 26 224 2.4E-22 T 29-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDC59_RS02365 dd8b880d7708ece1010b6bed1e9a1c50 326 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 249 306 8.8E-25 T 29-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDC59_RS02365 dd8b880d7708ece1010b6bed1e9a1c50 326 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 61 150 6.5E-24 T 29-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDC59_RS02365 dd8b880d7708ece1010b6bed1e9a1c50 326 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 254 324 5.0E-35 T 29-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDC59_RS02365 dd8b880d7708ece1010b6bed1e9a1c50 326 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 21 314 4.1E-106 T 29-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDC59_RS02365 dd8b880d7708ece1010b6bed1e9a1c50 326 SMART SM00662 20 230 5.5E-94 T 29-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDC59_RS02365 dd8b880d7708ece1010b6bed1e9a1c50 326 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 2 315 35.367 T 29-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDC59_RS02365 dd8b880d7708ece1010b6bed1e9a1c50 326 Gene3D G3DSA:1.10.150.20 244 326 1.9E-28 T 29-03-2018 CDC59_RS02365 dd8b880d7708ece1010b6bed1e9a1c50 326 SUPERFAMILY SSF56553 50 173 5.76E-41 T 29-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDC59_RS02365 dd8b880d7708ece1010b6bed1e9a1c50 326 SUPERFAMILY SSF47789 249 322 4.58E-27 T 29-03-2018 CDC59_RS02365 dd8b880d7708ece1010b6bed1e9a1c50 326 Gene3D G3DSA:3.30.1360.10 1 86 3.4E-16 T 29-03-2018 CDC59_RS02365 dd8b880d7708ece1010b6bed1e9a1c50 326 Gene3D G3DSA:3.30.1360.10 108 227 5.2E-31 T 29-03-2018 CDC59_RS02365 dd8b880d7708ece1010b6bed1e9a1c50 326 SUPERFAMILY SSF55257 175 228 5.0E-31 T 29-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDC59_RS02365 dd8b880d7708ece1010b6bed1e9a1c50 326 SUPERFAMILY SSF55257 5 50 5.0E-31 T 29-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDC59_RS08600 56ee95fd054b06f81055cd01aa861fdf 606 SUPERFAMILY SSF52540 4 206 5.75E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS08600 56ee95fd054b06f81055cd01aa861fdf 606 Gene3D G3DSA:2.40.30.10 189 300 1.1E-18 T 29-03-2018 CDC59_RS08600 56ee95fd054b06f81055cd01aa861fdf 606 Gene3D G3DSA:3.40.50.300 67 188 2.2E-30 T 29-03-2018 CDC59_RS08600 56ee95fd054b06f81055cd01aa861fdf 606 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 4 599 7.5E-287 T 29-03-2018 IPR006298 GTP-binding protein TypA GO:0005525 CDC59_RS08600 56ee95fd054b06f81055cd01aa861fdf 606 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 43 58 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site CDC59_RS08600 56ee95fd054b06f81055cd01aa861fdf 606 Gene3D G3DSA:2.40.50.250 483 573 9.4E-40 T 29-03-2018 CDC59_RS08600 56ee95fd054b06f81055cd01aa861fdf 606 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 5 153 1.5E-23 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CDC59_RS08600 56ee95fd054b06f81055cd01aa861fdf 606 Gene3D G3DSA:3.30.70.870 302 400 1.4E-30 T 29-03-2018 CDC59_RS08600 56ee95fd054b06f81055cd01aa861fdf 606 Pfam PF00679 Elongation factor G C-terminus 397 477 1.1E-21 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like CDC59_RS08600 56ee95fd054b06f81055cd01aa861fdf 606 SUPERFAMILY SSF50447 151 299 1.03E-27 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CDC59_RS08600 56ee95fd054b06f81055cd01aa861fdf 606 Pfam PF03144 Elongation factor Tu domain 2 218 289 2.5E-8 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CDC59_RS08600 56ee95fd054b06f81055cd01aa861fdf 606 Gene3D G3DSA:3.40.50.300 2 66 1.0E-10 T 29-03-2018 CDC59_RS08600 56ee95fd054b06f81055cd01aa861fdf 606 Pfam PF00009 Elongation factor Tu GTP binding domain 4 194 3.9E-55 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDC59_RS08600 56ee95fd054b06f81055cd01aa861fdf 606 SUPERFAMILY SSF54980 398 513 1.2E-27 T 29-03-2018 IPR035647 EF-G domain III/V-like CDC59_RS08600 56ee95fd054b06f81055cd01aa861fdf 606 Gene3D G3DSA:3.30.70.240 401 482 1.2E-17 T 29-03-2018 CDC59_RS08600 56ee95fd054b06f81055cd01aa861fdf 606 PRINTS PR00315 GTP-binding elongation factor signature 6 19 5.5E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDC59_RS08600 56ee95fd054b06f81055cd01aa861fdf 606 PRINTS PR00315 GTP-binding elongation factor signature 70 80 5.5E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDC59_RS08600 56ee95fd054b06f81055cd01aa861fdf 606 PRINTS PR00315 GTP-binding elongation factor signature 122 131 5.5E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDC59_RS08600 56ee95fd054b06f81055cd01aa861fdf 606 PRINTS PR00315 GTP-binding elongation factor signature 50 58 5.5E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDC59_RS08600 56ee95fd054b06f81055cd01aa861fdf 606 PRINTS PR00315 GTP-binding elongation factor signature 86 97 5.5E-15 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDC59_RS08600 56ee95fd054b06f81055cd01aa861fdf 606 SUPERFAMILY SSF54980 302 387 9.35E-13 T 29-03-2018 IPR035647 EF-G domain III/V-like CDC59_RS16000 8e7359b29aacb5b5f7e09100595ef253 453 Pfam PF00072 Response regulator receiver domain 18 127 2.1E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS16000 8e7359b29aacb5b5f7e09100595ef253 453 Gene3D G3DSA:1.10.8.60 326 402 3.2E-22 T 29-03-2018 CDC59_RS16000 8e7359b29aacb5b5f7e09100595ef253 453 SMART SM00448 16 127 1.5E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS16000 8e7359b29aacb5b5f7e09100595ef253 453 Pfam PF00158 Sigma-54 interaction domain 155 320 3.1E-66 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CDC59_RS16000 8e7359b29aacb5b5f7e09100595ef253 453 SUPERFAMILY SSF52172 18 198 1.42E-41 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS16000 8e7359b29aacb5b5f7e09100595ef253 453 SMART SM00382 175 317 9.9E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS16000 8e7359b29aacb5b5f7e09100595ef253 453 SUPERFAMILY SSF52540 155 393 2.95E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS16000 8e7359b29aacb5b5f7e09100595ef253 453 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 409 426 4.1E-8 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CDC59_RS16000 8e7359b29aacb5b5f7e09100595ef253 453 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 426 446 4.1E-8 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CDC59_RS16000 8e7359b29aacb5b5f7e09100595ef253 453 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 240 255 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CDC59_RS16000 8e7359b29aacb5b5f7e09100595ef253 453 Gene3D G3DSA:3.40.50.300 152 325 2.0E-26 T 29-03-2018 CDC59_RS16000 8e7359b29aacb5b5f7e09100595ef253 453 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 179 192 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CDC59_RS16000 8e7359b29aacb5b5f7e09100595ef253 453 SUPERFAMILY SSF46689 367 445 4.48E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS16000 8e7359b29aacb5b5f7e09100595ef253 453 Pfam PF02954 Bacterial regulatory protein, Fis family 405 443 1.3E-9 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CDC59_RS16000 8e7359b29aacb5b5f7e09100595ef253 453 Gene3D G3DSA:3.40.50.2300 8 151 5.3E-32 T 29-03-2018 CDC59_RS16000 8e7359b29aacb5b5f7e09100595ef253 453 Gene3D G3DSA:1.10.10.60 403 447 2.5E-13 T 29-03-2018 CDC59_RS16000 8e7359b29aacb5b5f7e09100595ef253 453 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 367 376 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site CDC59_RS15365 a6d2db3673e0d12fd36f72ba0e0ed539 408 Gene3D G3DSA:3.40.640.10 174 296 6.5E-43 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDC59_RS15365 a6d2db3673e0d12fd36f72ba0e0ed539 408 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 225 262 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CDC59_RS15365 a6d2db3673e0d12fd36f72ba0e0ed539 408 TIGRFAM TIGR01885 Orn_aminotrans: ornithine--oxo-acid transaminase 10 399 2.4E-140 T 29-03-2018 IPR010164 Ornithine aminotransferase GO:0004587 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CDC59_RS15365 a6d2db3673e0d12fd36f72ba0e0ed539 408 Gene3D G3DSA:3.90.1150.10 2 173 6.4E-42 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS15365 a6d2db3673e0d12fd36f72ba0e0ed539 408 Pfam PF00202 Aminotransferase class-III 17 398 9.4E-109 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CDC59_RS15365 a6d2db3673e0d12fd36f72ba0e0ed539 408 SUPERFAMILY SSF53383 14 401 2.79E-112 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS15365 a6d2db3673e0d12fd36f72ba0e0ed539 408 PIRSF PIRSF000521 177 402 5.9E-31 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CDC59_RS15365 a6d2db3673e0d12fd36f72ba0e0ed539 408 PIRSF PIRSF000521 11 158 2.6E-9 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CDC59_RS15365 a6d2db3673e0d12fd36f72ba0e0ed539 408 Gene3D G3DSA:3.90.1150.10 297 406 4.3E-21 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS14785 c73e1bae0c73199295e13160a07bc2f4 272 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 114 134 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CDC59_RS14785 c73e1bae0c73199295e13160a07bc2f4 272 Pfam PF00378 Enoyl-CoA hydratase/isomerase 39 270 6.4E-38 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CDC59_RS14785 c73e1bae0c73199295e13160a07bc2f4 272 Gene3D G3DSA:3.90.226.10 7 223 1.2E-42 T 29-03-2018 CDC59_RS14785 c73e1bae0c73199295e13160a07bc2f4 272 SUPERFAMILY SSF52096 15 269 1.66E-60 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CDC59_RS14785 c73e1bae0c73199295e13160a07bc2f4 272 Gene3D G3DSA:1.10.12.10 224 272 1.1E-8 T 29-03-2018 IPR014748 Crontonase, C-terminal CDC59_RS08920 005ff79cd865c4c7ff7180ddb02a928d 639 Gene3D G3DSA:3.40.50.2000 408 508 1.6E-10 T 29-03-2018 CDC59_RS08920 005ff79cd865c4c7ff7180ddb02a928d 639 Gene3D G3DSA:3.80.10.10 307 405 5.5E-10 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like CDC59_RS08920 005ff79cd865c4c7ff7180ddb02a928d 639 SMART SM00367 318 341 200.0 T 29-03-2018 IPR006553 Leucine-rich repeat, cysteine-containing subtype CDC59_RS08920 005ff79cd865c4c7ff7180ddb02a928d 639 SMART SM00367 455 479 250.0 T 29-03-2018 IPR006553 Leucine-rich repeat, cysteine-containing subtype CDC59_RS08920 005ff79cd865c4c7ff7180ddb02a928d 639 SMART SM00367 293 317 0.73 T 29-03-2018 IPR006553 Leucine-rich repeat, cysteine-containing subtype CDC59_RS08920 005ff79cd865c4c7ff7180ddb02a928d 639 SMART SM00367 568 593 55.0 T 29-03-2018 IPR006553 Leucine-rich repeat, cysteine-containing subtype CDC59_RS08920 005ff79cd865c4c7ff7180ddb02a928d 639 SMART SM00367 222 246 380.0 T 29-03-2018 IPR006553 Leucine-rich repeat, cysteine-containing subtype CDC59_RS08920 005ff79cd865c4c7ff7180ddb02a928d 639 Gene3D G3DSA:3.80.10.10 104 306 7.1E-23 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like CDC59_RS08920 005ff79cd865c4c7ff7180ddb02a928d 639 SUPERFAMILY SSF81383 93 146 3.27E-5 T 29-03-2018 IPR001810 F-box domain GO:0005515 CDC59_RS08920 005ff79cd865c4c7ff7180ddb02a928d 639 SUPERFAMILY SSF52047 372 623 4.45E-29 T 29-03-2018 CDC59_RS08920 005ff79cd865c4c7ff7180ddb02a928d 639 Gene3D G3DSA:3.80.10.10 509 625 9.8E-12 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like CDC59_RS08920 005ff79cd865c4c7ff7180ddb02a928d 639 SMART SM00368 596 619 92.0 T 29-03-2018 CDC59_RS08920 005ff79cd865c4c7ff7180ddb02a928d 639 SMART SM00368 245 268 10.0 T 29-03-2018 CDC59_RS08920 005ff79cd865c4c7ff7180ddb02a928d 639 SMART SM00368 269 298 40.0 T 29-03-2018 CDC59_RS08920 005ff79cd865c4c7ff7180ddb02a928d 639 SMART SM00368 520 549 4.3 T 29-03-2018 CDC59_RS08920 005ff79cd865c4c7ff7180ddb02a928d 639 SMART SM00368 317 346 9.8 T 29-03-2018 CDC59_RS08920 005ff79cd865c4c7ff7180ddb02a928d 639 SMART SM00368 455 483 7.3 T 29-03-2018 CDC59_RS08920 005ff79cd865c4c7ff7180ddb02a928d 639 SMART SM00368 431 454 37.0 T 29-03-2018 CDC59_RS08920 005ff79cd865c4c7ff7180ddb02a928d 639 SMART SM00368 163 189 79.0 T 29-03-2018 CDC59_RS08920 005ff79cd865c4c7ff7180ddb02a928d 639 SUPERFAMILY SSF52047 157 358 4.71E-32 T 29-03-2018 CDC59_RS08920 005ff79cd865c4c7ff7180ddb02a928d 639 Pfam PF13516 Leucine Rich repeat 522 542 0.13 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS08920 005ff79cd865c4c7ff7180ddb02a928d 639 Pfam PF13516 Leucine Rich repeat 430 453 1.6E-4 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS08920 005ff79cd865c4c7ff7180ddb02a928d 639 Pfam PF13516 Leucine Rich repeat 568 591 0.54 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS08920 005ff79cd865c4c7ff7180ddb02a928d 639 Pfam PF13516 Leucine Rich repeat 247 266 0.86 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS08920 005ff79cd865c4c7ff7180ddb02a928d 639 Pfam PF13516 Leucine Rich repeat 269 286 0.065 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS08920 005ff79cd865c4c7ff7180ddb02a928d 639 Pfam PF13516 Leucine Rich repeat 223 244 0.01 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS08920 005ff79cd865c4c7ff7180ddb02a928d 639 Pfam PF13516 Leucine Rich repeat 316 339 1.5E-4 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS08920 005ff79cd865c4c7ff7180ddb02a928d 639 Pfam PF13516 Leucine Rich repeat 293 315 0.47 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS08920 005ff79cd865c4c7ff7180ddb02a928d 639 Pfam PF13516 Leucine Rich repeat 455 477 0.081 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS01265 7e3d3409d68b34db66f3c99f9380f8ae 387 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 304 335 3.4E-5 T 29-03-2018 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 CDC59_RS01265 7e3d3409d68b34db66f3c99f9380f8ae 387 SUPERFAMILY SSF48452 17 110 3.45E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS01265 7e3d3409d68b34db66f3c99f9380f8ae 387 Gene3D G3DSA:1.25.40.10 6 120 1.5E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS01265 7e3d3409d68b34db66f3c99f9380f8ae 387 Gene3D G3DSA:3.40.50.2000 224 387 1.0E-32 T 29-03-2018 CDC59_RS01265 7e3d3409d68b34db66f3c99f9380f8ae 387 SUPERFAMILY SSF53756 130 367 1.79E-22 T 29-03-2018 CDC59_RS06270 43c705c8dd47c4448be1fe8f8530c82b 231 Gene3D G3DSA:3.40.50.620 6 224 6.8E-57 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDC59_RS06270 43c705c8dd47c4448be1fe8f8530c82b 231 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 13 70 2.6E-7 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CDC59_RS06270 43c705c8dd47c4448be1fe8f8530c82b 231 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 10 223 27.603 T 29-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 CDC59_RS06270 43c705c8dd47c4448be1fe8f8530c82b 231 Pfam PF01467 Cytidylyltransferase-like 14 197 4.6E-25 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CDC59_RS06270 43c705c8dd47c4448be1fe8f8530c82b 231 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 14 222 1.7E-44 T 29-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 CDC59_RS06270 43c705c8dd47c4448be1fe8f8530c82b 231 SUPERFAMILY SSF52374 9 223 6.57E-50 T 29-03-2018 CDC59_RS20350 c3b19e2dbf69aa637b3918df9415e89b 491 SUPERFAMILY SSF54368 19 114 1.31E-32 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CDC59_RS20350 c3b19e2dbf69aa637b3918df9415e89b 491 SUPERFAMILY SSF55931 119 490 1.18E-137 T 29-03-2018 CDC59_RS20350 c3b19e2dbf69aa637b3918df9415e89b 491 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 31 111 1.3E-29 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CDC59_RS20350 c3b19e2dbf69aa637b3918df9415e89b 491 Gene3D G3DSA:3.30.590.10 121 478 1.2E-125 T 29-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CDC59_RS20350 c3b19e2dbf69aa637b3918df9415e89b 491 SMART SM01230 118 400 6.1E-149 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CDC59_RS20350 c3b19e2dbf69aa637b3918df9415e89b 491 ProSitePatterns PS00180 Glutamine synthetase signature 1. 66 84 - T 29-03-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CDC59_RS20350 c3b19e2dbf69aa637b3918df9415e89b 491 Pfam PF00120 Glutamine synthetase, catalytic domain 119 488 3.8E-134 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CDC59_RS20350 c3b19e2dbf69aa637b3918df9415e89b 491 Gene3D G3DSA:3.10.20.70 18 120 2.3E-26 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CDC59_RS20350 c3b19e2dbf69aa637b3918df9415e89b 491 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 21 490 2.1E-198 T 29-03-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CDC59_RS20350 c3b19e2dbf69aa637b3918df9415e89b 491 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 278 293 - T 29-03-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CDC59_RS03630 dcec6cd4445e166440c7eb81c2962825 485 SUPERFAMILY SSF52467 312 484 5.38E-75 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CDC59_RS03630 dcec6cd4445e166440c7eb81c2962825 485 PIRSF PIRSF000204 1 485 5.6E-208 T 29-03-2018 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2 CDC59_RS03630 dcec6cd4445e166440c7eb81c2962825 485 Gene3D G3DSA:3.40.50.1220 311 485 5.4E-83 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CDC59_RS03630 dcec6cd4445e166440c7eb81c2962825 485 Pfam PF02233 NAD(P) transhydrogenase beta subunit 7 482 9.1E-190 T 29-03-2018 IPR034300 NADP transhydrogenase beta-like domain KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 CDC59_RS13330 5ffafae2035467e90664c47564a077c8 169 PIRSF PIRSF001338 5 164 3.1E-62 T 29-03-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 CDC59_RS13330 5ffafae2035467e90664c47564a077c8 169 SUPERFAMILY SSF52255 9 162 7.06E-64 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CDC59_RS13330 5ffafae2035467e90664c47564a077c8 169 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 10 157 1.6E-61 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CDC59_RS13330 5ffafae2035467e90664c47564a077c8 169 Pfam PF00731 AIR carboxylase 10 157 8.4E-62 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CDC59_RS13330 5ffafae2035467e90664c47564a077c8 169 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 10 163 30.788 T 29-03-2018 IPR033747 Class I PurE CDC59_RS13330 5ffafae2035467e90664c47564a077c8 169 Gene3D G3DSA:3.40.50.7700 1 164 4.0E-65 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CDC59_RS13330 5ffafae2035467e90664c47564a077c8 169 SMART SM01001 8 159 1.6E-97 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CDC59_RS12785 283e2c80ce3e6295ffaacad5a8aba76d 291 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 1 281 45.361 T 29-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CDC59_RS12785 283e2c80ce3e6295ffaacad5a8aba76d 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 102 118 4.2E-18 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CDC59_RS12785 283e2c80ce3e6295ffaacad5a8aba76d 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 127 144 4.2E-18 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CDC59_RS12785 283e2c80ce3e6295ffaacad5a8aba76d 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 34 55 4.2E-18 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CDC59_RS12785 283e2c80ce3e6295ffaacad5a8aba76d 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 70 88 4.2E-18 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CDC59_RS12785 283e2c80ce3e6295ffaacad5a8aba76d 291 SUPERFAMILY SSF51569 1 283 6.07E-83 T 29-03-2018 CDC59_RS12785 283e2c80ce3e6295ffaacad5a8aba76d 291 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 9 280 2.0E-68 T 29-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CDC59_RS12785 283e2c80ce3e6295ffaacad5a8aba76d 291 Gene3D G3DSA:3.20.20.70 1 290 4.3E-84 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS12785 283e2c80ce3e6295ffaacad5a8aba76d 291 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 132 162 - T 29-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 CDC59_RS12785 283e2c80ce3e6295ffaacad5a8aba76d 291 SMART SM01130 1 283 1.8E-96 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CDC59_RS12785 283e2c80ce3e6295ffaacad5a8aba76d 291 PIRSF PIRSF001365 1 288 4.2E-75 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CDC59_RS12785 283e2c80ce3e6295ffaacad5a8aba76d 291 Pfam PF00701 Dihydrodipicolinate synthetase family 2 279 9.2E-68 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CDC59_RS11925 26ab007b9ebfbcab00faa4956ccaf640 150 Gene3D G3DSA:1.10.3830.10 31 143 1.5E-36 T 29-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 CDC59_RS11925 26ab007b9ebfbcab00faa4956ccaf640 150 Pfam PF01219 Prokaryotic diacylglycerol kinase 40 140 2.1E-31 T 29-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 CDC59_RS11925 26ab007b9ebfbcab00faa4956ccaf640 150 ProSitePatterns PS01069 Prokaryotic diacylglycerol kinase signature. 94 105 - T 29-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 CDC59_RS19280 c3bc88a49290f2f0ebcd1efebc768f8f 323 Gene3D G3DSA:3.30.460.20 1 135 3.6E-31 T 29-03-2018 CDC59_RS19280 c3bc88a49290f2f0ebcd1efebc768f8f 323 SUPERFAMILY SSF143865 2 256 7.59E-68 T 29-03-2018 CDC59_RS19280 c3bc88a49290f2f0ebcd1efebc768f8f 323 Pfam PF01544 CorA-like Mg2+ transporter protein 33 316 2.0E-58 T 29-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 CDC59_RS19280 c3bc88a49290f2f0ebcd1efebc768f8f 323 Gene3D G3DSA:1.20.58.340 256 323 1.9E-13 T 29-03-2018 CDC59_RS19280 c3bc88a49290f2f0ebcd1efebc768f8f 323 SUPERFAMILY SSF144083 259 320 6.54E-16 T 29-03-2018 CDC59_RS19280 c3bc88a49290f2f0ebcd1efebc768f8f 323 Gene3D G3DSA:1.20.58.340 139 255 8.8E-28 T 29-03-2018 CDC59_RS21215 4106861935d1d1b1a10831409d6c5cf1 507 Pfam PF00171 Aldehyde dehydrogenase family 29 487 1.3E-145 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CDC59_RS21215 4106861935d1d1b1a10831409d6c5cf1 507 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 14 491 5.4E-211 T 29-03-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373|Reactome: R-HSA-70895 CDC59_RS21215 4106861935d1d1b1a10831409d6c5cf1 507 Gene3D G3DSA:3.40.309.10 273 470 7.1E-67 T 29-03-2018 CDC59_RS21215 4106861935d1d1b1a10831409d6c5cf1 507 SUPERFAMILY SSF53720 13 493 1.01E-153 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CDC59_RS21215 4106861935d1d1b1a10831409d6c5cf1 507 Gene3D G3DSA:3.40.605.10 5 272 1.2E-86 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CDC59_RS21215 4106861935d1d1b1a10831409d6c5cf1 507 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 284 295 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CDC59_RS00005 0b5b6a5d019d858c4626b9845da46df8 44 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 29-03-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS00005 0b5b6a5d019d858c4626b9845da46df8 44 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 1 44 4.0E-24 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS00005 0b5b6a5d019d858c4626b9845da46df8 44 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 15.76 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS00005 0b5b6a5d019d858c4626b9845da46df8 44 Pfam PF00468 Ribosomal protein L34 1 43 9.4E-23 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS00005 0b5b6a5d019d858c4626b9845da46df8 44 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 42 7.0E-16 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS07615 6e552ee47eed99abe5e190c4527e4acd 108 PRINTS PR00354 7Fe ferredoxin signature 9 19 1.1E-14 T 29-03-2018 IPR000813 7Fe ferredoxin GO:0009055 CDC59_RS07615 6e552ee47eed99abe5e190c4527e4acd 108 PRINTS PR00354 7Fe ferredoxin signature 35 52 1.1E-14 T 29-03-2018 IPR000813 7Fe ferredoxin GO:0009055 CDC59_RS07615 6e552ee47eed99abe5e190c4527e4acd 108 PRINTS PR00354 7Fe ferredoxin signature 19 29 1.1E-14 T 29-03-2018 IPR000813 7Fe ferredoxin GO:0009055 CDC59_RS07615 6e552ee47eed99abe5e190c4527e4acd 108 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CDC59_RS07615 6e552ee47eed99abe5e190c4527e4acd 108 Pfam PF12800 4Fe-4S binding domain 7 23 0.22 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CDC59_RS07615 6e552ee47eed99abe5e190c4527e4acd 108 Pfam PF11953 Domain of unknown function (DUF3470) 66 108 7.4E-20 T 29-03-2018 IPR022569 Ferredoxin, C-terminal CDC59_RS07615 6e552ee47eed99abe5e190c4527e4acd 108 Gene3D G3DSA:3.30.70.20 2 44 1.6E-12 T 29-03-2018 CDC59_RS07615 6e552ee47eed99abe5e190c4527e4acd 108 SUPERFAMILY SSF54862 3 85 7.15E-23 T 29-03-2018 CDC59_RS07615 6e552ee47eed99abe5e190c4527e4acd 108 Gene3D G3DSA:3.30.70.20 45 107 1.9E-9 T 29-03-2018 CDC59_RS07615 6e552ee47eed99abe5e190c4527e4acd 108 Pfam PF00037 4Fe-4S binding domain 34 56 1.7E-7 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CDC59_RS03335 63c0efd2cd19b659adc03c930986f20f 402 Gene3D G3DSA:1.10.620.20 51 383 5.1E-103 T 29-03-2018 CDC59_RS03335 63c0efd2cd19b659adc03c930986f20f 402 Pfam PF00268 Ribonucleotide reductase, small chain 82 369 1.5E-84 T 29-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CDC59_RS03335 63c0efd2cd19b659adc03c930986f20f 402 SUPERFAMILY SSF47240 66 373 1.27E-96 T 29-03-2018 IPR009078 Ferritin-like superfamily CDC59_RS03335 63c0efd2cd19b659adc03c930986f20f 402 PIRSF PIRSF000355 54 402 4.0E-133 T 29-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CDC59_RS19765 1ad81b08a10a86c7eb374425f9d3c4ae 1093 Pfam PF13296 Putative type VI secretion system Rhs element Vgr 616 723 6.2E-31 T 29-03-2018 IPR028244 Putative type VI secretion system, Rhs element associated Vgr domain CDC59_RS19765 1ad81b08a10a86c7eb374425f9d3c4ae 1093 Pfam PF05954 Phage late control gene D protein (GPD) 37 355 2.2E-63 T 29-03-2018 CDC59_RS19765 1ad81b08a10a86c7eb374425f9d3c4ae 1093 Pfam PF10106 Uncharacterized protein conserved in bacteria (DUF2345) 771 927 1.6E-35 T 29-03-2018 IPR018769 Domain of unknown function DUF2345, Vgr C-terminal CDC59_RS19765 1ad81b08a10a86c7eb374425f9d3c4ae 1093 SUPERFAMILY SSF69279 20 202 1.45E-37 T 29-03-2018 CDC59_RS19765 1ad81b08a10a86c7eb374425f9d3c4ae 1093 Gene3D G3DSA:2.40.50.230 451 540 5.8E-22 T 29-03-2018 IPR006531 Gp5 N-terminal CDC59_RS19765 1ad81b08a10a86c7eb374425f9d3c4ae 1093 Gene3D G3DSA:3.55.50.10 106 206 2.4E-16 T 29-03-2018 CDC59_RS19765 1ad81b08a10a86c7eb374425f9d3c4ae 1093 SUPERFAMILY SSF69255 446 540 3.4E-17 T 29-03-2018 CDC59_RS01525 78e3aa6c95ef597198de79a21c814b5d 287 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 190 272 2.2E-9 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS01525 78e3aa6c95ef597198de79a21c814b5d 287 Gene3D G3DSA:1.10.760.10 107 287 5.3E-17 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS01525 78e3aa6c95ef597198de79a21c814b5d 287 SUPERFAMILY SSF46626 184 278 3.62E-17 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS10080 44c276ea7e1e88664d1fdcfba9e4646a 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 223 243 2.6E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS10080 44c276ea7e1e88664d1fdcfba9e4646a 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 2.6E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS10080 44c276ea7e1e88664d1fdcfba9e4646a 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 185 2.6E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS10080 44c276ea7e1e88664d1fdcfba9e4646a 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 156 2.6E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS10080 44c276ea7e1e88664d1fdcfba9e4646a 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 204 2.6E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS10080 44c276ea7e1e88664d1fdcfba9e4646a 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 95 106 2.6E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS10080 44c276ea7e1e88664d1fdcfba9e4646a 261 Gene3D G3DSA:3.40.50.720 9 47 6.0E-7 T 29-03-2018 CDC59_RS10080 44c276ea7e1e88664d1fdcfba9e4646a 261 Gene3D G3DSA:3.40.50.720 48 261 3.8E-58 T 29-03-2018 CDC59_RS10080 44c276ea7e1e88664d1fdcfba9e4646a 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 259 5.6E-53 T 29-03-2018 CDC59_RS10080 44c276ea7e1e88664d1fdcfba9e4646a 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 166 185 1.6E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS10080 44c276ea7e1e88664d1fdcfba9e4646a 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 154 1.6E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS10080 44c276ea7e1e88664d1fdcfba9e4646a 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 95 106 1.6E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS10080 44c276ea7e1e88664d1fdcfba9e4646a 261 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 13 202 0.0038 T 29-03-2018 CDC59_RS10080 44c276ea7e1e88664d1fdcfba9e4646a 261 SUPERFAMILY SSF51735 14 260 3.44E-71 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS10045 e86fa1cf899bc85ece9a1c2f12178359 353 Pfam PF13609 Gram-negative porin 8 325 3.8E-53 T 29-03-2018 CDC59_RS10045 e86fa1cf899bc85ece9a1c2f12178359 353 SUPERFAMILY SSF56935 22 353 1.68E-83 T 29-03-2018 CDC59_RS10045 e86fa1cf899bc85ece9a1c2f12178359 353 PRINTS PR00184 Neisseria sp. porin signature 56 81 4.9E-7 T 29-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 CDC59_RS10045 e86fa1cf899bc85ece9a1c2f12178359 353 PRINTS PR00184 Neisseria sp. porin signature 189 206 4.9E-7 T 29-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 CDC59_RS10045 e86fa1cf899bc85ece9a1c2f12178359 353 PRINTS PR00184 Neisseria sp. porin signature 297 321 4.9E-7 T 29-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 CDC59_RS10045 e86fa1cf899bc85ece9a1c2f12178359 353 Gene3D G3DSA:2.40.160.10 10 353 1.5E-73 T 29-03-2018 CDC59_RS06135 54a78cd7d77850d4e437a914a70b58b0 347 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 1 339 63.732 T 29-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CDC59_RS06135 54a78cd7d77850d4e437a914a70b58b0 347 Gene3D G3DSA:3.30.420.40 1 144 6.8E-41 T 29-03-2018 CDC59_RS06135 54a78cd7d77850d4e437a914a70b58b0 347 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 131 143 1.0E-51 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CDC59_RS06135 54a78cd7d77850d4e437a914a70b58b0 347 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 97 116 1.0E-51 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CDC59_RS06135 54a78cd7d77850d4e437a914a70b58b0 347 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 1.0E-51 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CDC59_RS06135 54a78cd7d77850d4e437a914a70b58b0 347 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 76 96 1.0E-51 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CDC59_RS06135 54a78cd7d77850d4e437a914a70b58b0 347 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 268 277 1.0E-51 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CDC59_RS06135 54a78cd7d77850d4e437a914a70b58b0 347 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 154 175 1.0E-51 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CDC59_RS06135 54a78cd7d77850d4e437a914a70b58b0 347 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 3 318 2.5E-132 T 29-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CDC59_RS06135 54a78cd7d77850d4e437a914a70b58b0 347 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 4 311 9.1E-113 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CDC59_RS06135 54a78cd7d77850d4e437a914a70b58b0 347 SUPERFAMILY SSF53067 101 314 3.33E-47 T 29-03-2018 CDC59_RS06135 54a78cd7d77850d4e437a914a70b58b0 347 Gene3D G3DSA:3.30.420.40 145 294 1.8E-17 T 29-03-2018 CDC59_RS06135 54a78cd7d77850d4e437a914a70b58b0 347 Pfam PF00814 Glycoprotease family 25 312 6.3E-99 T 29-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CDC59_RS06135 54a78cd7d77850d4e437a914a70b58b0 347 SUPERFAMILY SSF53067 3 121 9.06E-31 T 29-03-2018 CDC59_RS16365 d6e41087e888f1d96ee45434f3420817 869 Gene3D G3DSA:3.40.1060.10 228 358 6.3E-40 T 29-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS16365 d6e41087e888f1d96ee45434f3420817 869 PRINTS PR00415 Aconitase family signature 162 170 2.1E-25 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS16365 d6e41087e888f1d96ee45434f3420817 869 PRINTS PR00415 Aconitase family signature 281 294 2.1E-25 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS16365 d6e41087e888f1d96ee45434f3420817 869 PRINTS PR00415 Aconitase family signature 267 280 2.1E-25 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS16365 d6e41087e888f1d96ee45434f3420817 869 PRINTS PR00415 Aconitase family signature 191 204 2.1E-25 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS16365 d6e41087e888f1d96ee45434f3420817 869 PRINTS PR00415 Aconitase family signature 205 220 2.1E-25 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS16365 d6e41087e888f1d96ee45434f3420817 869 PRINTS PR00415 Aconitase family signature 464 477 2.1E-25 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS16365 d6e41087e888f1d96ee45434f3420817 869 PRINTS PR00415 Aconitase family signature 402 413 2.1E-25 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS16365 d6e41087e888f1d96ee45434f3420817 869 PRINTS PR00415 Aconitase family signature 138 151 2.1E-25 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS16365 d6e41087e888f1d96ee45434f3420817 869 SUPERFAMILY SSF53732 24 589 3.79E-181 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS16365 d6e41087e888f1d96ee45434f3420817 869 Gene3D G3DSA:3.30.499.10 359 547 2.4E-53 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS16365 d6e41087e888f1d96ee45434f3420817 869 Pfam PF00694 Aconitase C-terminal domain 661 791 3.0E-28 T 29-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS16365 d6e41087e888f1d96ee45434f3420817 869 Pfam PF00330 Aconitase family (aconitate hydratase) 68 533 6.6E-143 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS16365 d6e41087e888f1d96ee45434f3420817 869 TIGRFAM TIGR02333 2met_isocit_dHY: 2-methylisocitrate dehydratase, Fe/S-dependent 2 863 0.0 T 29-03-2018 IPR012708 2-methylisocitrate dehydratase AcnD, Fe/S-dependent GO:0019679 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3 CDC59_RS16365 d6e41087e888f1d96ee45434f3420817 869 Gene3D G3DSA:3.30.499.10 2 227 7.3E-59 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CDC59_RS16365 d6e41087e888f1d96ee45434f3420817 869 SUPERFAMILY SSF52016 599 861 7.46E-66 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CDC59_RS16365 d6e41087e888f1d96ee45434f3420817 869 Gene3D G3DSA:3.20.19.10 624 863 5.8E-66 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CDC59_RS15505 a738d55e26c5a1462d265f2b692d8534 378 Gene3D G3DSA:3.10.580.10 221 375 5.7E-36 T 29-03-2018 CDC59_RS15505 a738d55e26c5a1462d265f2b692d8534 378 Pfam PF00571 CBS domain 238 287 6.0E-12 T 29-03-2018 IPR000644 CBS domain CDC59_RS15505 a738d55e26c5a1462d265f2b692d8534 378 Pfam PF00571 CBS domain 313 367 1.2E-12 T 29-03-2018 IPR000644 CBS domain CDC59_RS15505 a738d55e26c5a1462d265f2b692d8534 378 SUPERFAMILY SSF54631 228 368 7.79E-35 T 29-03-2018 CDC59_RS15505 a738d55e26c5a1462d265f2b692d8534 378 Pfam PF04982 HPP family 56 176 4.8E-38 T 29-03-2018 IPR007065 HPP CDC59_RS15505 a738d55e26c5a1462d265f2b692d8534 378 SMART SM00116 320 368 1.1E-10 T 29-03-2018 IPR000644 CBS domain CDC59_RS15505 a738d55e26c5a1462d265f2b692d8534 378 SMART SM00116 244 292 6.9E-10 T 29-03-2018 IPR000644 CBS domain CDC59_RS01900 2e9aef79e09ab2bcd13f1856b18995aa 386 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 19 300 1.9E-63 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CDC59_RS01900 2e9aef79e09ab2bcd13f1856b18995aa 386 SUPERFAMILY SSF160240 219 300 4.32E-19 T 29-03-2018 CDC59_RS01900 2e9aef79e09ab2bcd13f1856b18995aa 386 SUPERFAMILY SSF161111 15 217 5.75E-52 T 29-03-2018 CDC59_RS01900 2e9aef79e09ab2bcd13f1856b18995aa 386 Gene3D G3DSA:3.30.70.1350 216 306 2.5E-19 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CDC59_RS01900 2e9aef79e09ab2bcd13f1856b18995aa 386 Gene3D G3DSA:1.20.1510.10 17 215 5.7E-44 T 29-03-2018 CDC59_RS01900 2e9aef79e09ab2bcd13f1856b18995aa 386 Pfam PF16916 Dimerisation domain of Zinc Transporter 221 299 1.5E-18 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CDC59_RS01900 2e9aef79e09ab2bcd13f1856b18995aa 386 Pfam PF01545 Cation efflux family 23 216 1.4E-43 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CDC59_RS15210 8cba2c46b4fa313edf434582478d8c0d 124 Pfam PF00708 Acylphosphatase 37 118 3.6E-21 T 29-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CDC59_RS15210 8cba2c46b4fa313edf434582478d8c0d 124 SUPERFAMILY SSF54975 34 119 8.5E-23 T 29-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CDC59_RS15210 8cba2c46b4fa313edf434582478d8c0d 124 PRINTS PR00112 Acylphosphatase signature 55 80 3.4E-5 T 29-03-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CDC59_RS15210 8cba2c46b4fa313edf434582478d8c0d 124 PRINTS PR00112 Acylphosphatase signature 34 49 3.4E-5 T 29-03-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CDC59_RS15210 8cba2c46b4fa313edf434582478d8c0d 124 Gene3D G3DSA:3.30.70.100 31 120 8.9E-21 T 29-03-2018 CDC59_RS06240 7a8513a71e0200e7b2f25df35e5de982 201 TIGRFAM TIGR01926 peroxid_rel: uncharacterized peroxidase-related enzyme 13 190 1.8E-74 T 29-03-2018 IPR010195 Uncharacterised peroxidase-related CDC59_RS06240 7a8513a71e0200e7b2f25df35e5de982 201 Gene3D G3DSA:1.20.1290.10 54 191 1.1E-27 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CDC59_RS06240 7a8513a71e0200e7b2f25df35e5de982 201 Pfam PF02627 Carboxymuconolactone decarboxylase family 52 138 1.5E-12 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CDC59_RS06240 7a8513a71e0200e7b2f25df35e5de982 201 Gene3D G3DSA:1.20.5.810 21 53 6.0E-21 T 29-03-2018 CDC59_RS06240 7a8513a71e0200e7b2f25df35e5de982 201 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 71 118 4.8E-12 T 29-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CDC59_RS06240 7a8513a71e0200e7b2f25df35e5de982 201 SUPERFAMILY SSF69118 9 192 8.77E-55 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CDC59_RS10745 51193a6e9a67d6da247041ddd7e0bbab 232 SMART SM00882 5 217 1.9E-94 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CDC59_RS10745 51193a6e9a67d6da247041ddd7e0bbab 232 SUPERFAMILY SSF100950 2 227 3.09E-90 T 29-03-2018 CDC59_RS10745 51193a6e9a67d6da247041ddd7e0bbab 232 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 18 33 - T 29-03-2018 IPR004163 Coenzyme A transferase binding site GO:0008152|GO:0008410 Reactome: R-HSA-77108 CDC59_RS10745 51193a6e9a67d6da247041ddd7e0bbab 232 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 1 216 7.4E-82 T 29-03-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 CDC59_RS10745 51193a6e9a67d6da247041ddd7e0bbab 232 Pfam PF01144 Coenzyme A transferase 6 217 1.1E-81 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CDC59_RS10745 51193a6e9a67d6da247041ddd7e0bbab 232 Gene3D G3DSA:3.40.1080.10 1 232 1.2E-99 T 29-03-2018 CDC59_RS15370 ab3c7029156f508064594076961a6160 309 SUPERFAMILY SSF52768 5 302 4.5E-71 T 29-03-2018 CDC59_RS15370 ab3c7029156f508064594076961a6160 309 ProSitePatterns PS01053 Arginase family signature. 225 246 - T 29-03-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 CDC59_RS15370 ab3c7029156f508064594076961a6160 309 PRINTS PR00116 Arginase signature 119 146 2.9E-32 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CDC59_RS15370 ab3c7029156f508064594076961a6160 309 PRINTS PR00116 Arginase signature 93 108 2.9E-32 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CDC59_RS15370 ab3c7029156f508064594076961a6160 309 PRINTS PR00116 Arginase signature 173 191 2.9E-32 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CDC59_RS15370 ab3c7029156f508064594076961a6160 309 PRINTS PR00116 Arginase signature 222 251 2.9E-32 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CDC59_RS15370 ab3c7029156f508064594076961a6160 309 Pfam PF00491 Arginase family 6 293 8.5E-61 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CDC59_RS15370 ab3c7029156f508064594076961a6160 309 Gene3D G3DSA:3.40.800.10 3 309 4.6E-70 T 29-03-2018 CDC59_RS21300 1995c2dcf4c5774be76e8b336604902f 340 Gene3D G3DSA:3.40.50.2300 65 180 3.9E-32 T 29-03-2018 CDC59_RS21300 1995c2dcf4c5774be76e8b336604902f 340 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 20 30 3.2E-6 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDC59_RS21300 1995c2dcf4c5774be76e8b336604902f 340 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 10 20 3.2E-6 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDC59_RS21300 1995c2dcf4c5774be76e8b336604902f 340 Gene3D G3DSA:1.10.10.10 4 23 0.021 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS21300 1995c2dcf4c5774be76e8b336604902f 340 SMART SM00354 8 78 8.7E-32 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDC59_RS21300 1995c2dcf4c5774be76e8b336604902f 340 SUPERFAMILY SSF53822 65 334 6.23E-63 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CDC59_RS21300 1995c2dcf4c5774be76e8b336604902f 340 Pfam PF00356 Bacterial regulatory proteins, lacI family 10 55 1.2E-19 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDC59_RS21300 1995c2dcf4c5774be76e8b336604902f 340 ProSitePatterns PS00356 LacI-type HTH domain signature. 11 29 - T 29-03-2018 CDC59_RS21300 1995c2dcf4c5774be76e8b336604902f 340 Gene3D G3DSA:1.10.260.40 24 64 8.9E-21 T 29-03-2018 CDC59_RS21300 1995c2dcf4c5774be76e8b336604902f 340 Pfam PF13377 Periplasmic binding protein-like domain 175 340 1.9E-36 T 29-03-2018 CDC59_RS21300 1995c2dcf4c5774be76e8b336604902f 340 Gene3D G3DSA:3.40.50.2300 181 327 2.8E-40 T 29-03-2018 CDC59_RS21300 1995c2dcf4c5774be76e8b336604902f 340 SUPERFAMILY SSF47413 7 66 9.85E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDC59_RS02335 8e4aad6d53b6622b40fe2332eceab7f8 440 ProSitePatterns PS00756 Protein secY signature 2. 164 181 - T 29-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CDC59_RS02335 8e4aad6d53b6622b40fe2332eceab7f8 440 PRINTS PR00303 Preprotein translocase SecY subunit signature 110 133 9.9E-94 T 29-03-2018 CDC59_RS02335 8e4aad6d53b6622b40fe2332eceab7f8 440 PRINTS PR00303 Preprotein translocase SecY subunit signature 263 282 9.9E-94 T 29-03-2018 CDC59_RS02335 8e4aad6d53b6622b40fe2332eceab7f8 440 PRINTS PR00303 Preprotein translocase SecY subunit signature 171 194 9.9E-94 T 29-03-2018 CDC59_RS02335 8e4aad6d53b6622b40fe2332eceab7f8 440 PRINTS PR00303 Preprotein translocase SecY subunit signature 365 383 9.9E-94 T 29-03-2018 CDC59_RS02335 8e4aad6d53b6622b40fe2332eceab7f8 440 PRINTS PR00303 Preprotein translocase SecY subunit signature 397 415 9.9E-94 T 29-03-2018 CDC59_RS02335 8e4aad6d53b6622b40fe2332eceab7f8 440 PRINTS PR00303 Preprotein translocase SecY subunit signature 310 332 9.9E-94 T 29-03-2018 CDC59_RS02335 8e4aad6d53b6622b40fe2332eceab7f8 440 PRINTS PR00303 Preprotein translocase SecY subunit signature 17 35 9.9E-94 T 29-03-2018 CDC59_RS02335 8e4aad6d53b6622b40fe2332eceab7f8 440 PRINTS PR00303 Preprotein translocase SecY subunit signature 69 89 9.9E-94 T 29-03-2018 CDC59_RS02335 8e4aad6d53b6622b40fe2332eceab7f8 440 PRINTS PR00303 Preprotein translocase SecY subunit signature 145 170 9.9E-94 T 29-03-2018 CDC59_RS02335 8e4aad6d53b6622b40fe2332eceab7f8 440 ProSitePatterns PS00755 Protein secY signature 1. 70 89 - T 29-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CDC59_RS02335 8e4aad6d53b6622b40fe2332eceab7f8 440 Gene3D G3DSA:1.10.3370.10 1 434 5.5E-161 T 29-03-2018 CDC59_RS02335 8e4aad6d53b6622b40fe2332eceab7f8 440 Hamap MF_01465 Protein translocase subunit SecY [secY]. 4 428 29.465 T 29-03-2018 IPR026593 Protein translocase subunit SecY CDC59_RS02335 8e4aad6d53b6622b40fe2332eceab7f8 440 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 14 424 6.4E-129 T 29-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CDC59_RS02335 8e4aad6d53b6622b40fe2332eceab7f8 440 PIRSF PIRSF004557 1 435 5.1E-124 T 29-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CDC59_RS02335 8e4aad6d53b6622b40fe2332eceab7f8 440 SUPERFAMILY SSF103491 4 419 2.09E-131 T 29-03-2018 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CDC59_RS02335 8e4aad6d53b6622b40fe2332eceab7f8 440 Pfam PF00344 SecY translocase 70 412 1.1E-115 T 29-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CDC59_RS05495 c301ac9d2e9bf0f7490d7506d03f89aa 140 Pfam PF00216 Bacterial DNA-binding protein 3 92 7.2E-27 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CDC59_RS05495 c301ac9d2e9bf0f7490d7506d03f89aa 140 TIGRFAM TIGR00988 hip: integration host factor, beta subunit 3 93 1.3E-36 T 29-03-2018 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 CDC59_RS05495 c301ac9d2e9bf0f7490d7506d03f89aa 140 Hamap MF_00381 Integration host factor subunit beta [ihfB]. 3 96 28.781 T 29-03-2018 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 CDC59_RS05495 c301ac9d2e9bf0f7490d7506d03f89aa 140 SUPERFAMILY SSF47729 3 93 2.21E-28 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CDC59_RS05495 c301ac9d2e9bf0f7490d7506d03f89aa 140 SMART SM00411 3 93 1.6E-37 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CDC59_RS05495 c301ac9d2e9bf0f7490d7506d03f89aa 140 PRINTS PR01727 Prokaryotic integration host factor signature 77 91 1.9E-16 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CDC59_RS05495 c301ac9d2e9bf0f7490d7506d03f89aa 140 PRINTS PR01727 Prokaryotic integration host factor signature 61 74 1.9E-16 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CDC59_RS05495 c301ac9d2e9bf0f7490d7506d03f89aa 140 PRINTS PR01727 Prokaryotic integration host factor signature 43 58 1.9E-16 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CDC59_RS05495 c301ac9d2e9bf0f7490d7506d03f89aa 140 Gene3D G3DSA:4.10.520.10 1 100 5.9E-29 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CDC59_RS04190 0bc96771d25a70565751400af2346615 218 SUPERFAMILY SSF51197 23 216 2.88E-60 T 29-03-2018 CDC59_RS04190 0bc96771d25a70565751400af2346615 218 Pfam PF13532 2OG-Fe(II) oxygenase superfamily 38 215 1.4E-52 T 29-03-2018 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like CDC59_RS04190 0bc96771d25a70565751400af2346615 218 Gene3D G3DSA:2.60.120.590 16 218 1.1E-47 T 29-03-2018 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like CDC59_RS09040 18bd18a4d5a0618f30461c28de9c1f44 271 Gene3D G3DSA:3.40.50.10780 1 209 3.2E-78 T 29-03-2018 IPR027476 D-aminopeptidase, N-terminal CDC59_RS09040 18bd18a4d5a0618f30461c28de9c1f44 271 PIRSF PIRSF015853 1 271 2.0E-104 T 29-03-2018 IPR007035 Peptidase M55, D-aminopeptidase CDC59_RS09040 18bd18a4d5a0618f30461c28de9c1f44 271 Pfam PF04951 D-aminopeptidase 1 261 3.2E-93 T 29-03-2018 IPR007035 Peptidase M55, D-aminopeptidase CDC59_RS09040 18bd18a4d5a0618f30461c28de9c1f44 271 SUPERFAMILY SSF63992 1 271 1.22E-101 T 29-03-2018 IPR007035 Peptidase M55, D-aminopeptidase CDC59_RS09040 18bd18a4d5a0618f30461c28de9c1f44 271 Gene3D G3DSA:3.30.1360.130 210 267 8.0E-10 T 29-03-2018 CDC59_RS07540 4233005f09a5234bfcc537ca89636f81 299 SUPERFAMILY SSF46785 1 109 5.62E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS07540 4233005f09a5234bfcc537ca89636f81 299 Pfam PF03466 LysR substrate binding domain 88 285 8.6E-33 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS07540 4233005f09a5234bfcc537ca89636f81 299 SUPERFAMILY SSF53850 88 285 1.21E-31 T 29-03-2018 CDC59_RS07540 4233005f09a5234bfcc537ca89636f81 299 Gene3D G3DSA:3.40.190.10 90 174 7.7E-20 T 29-03-2018 CDC59_RS07540 4233005f09a5234bfcc537ca89636f81 299 Gene3D G3DSA:3.40.190.10 175 247 3.8E-10 T 29-03-2018 CDC59_RS07540 4233005f09a5234bfcc537ca89636f81 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.0E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS07540 4233005f09a5234bfcc537ca89636f81 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.0E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS07540 4233005f09a5234bfcc537ca89636f81 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.0E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS07540 4233005f09a5234bfcc537ca89636f81 299 Gene3D G3DSA:1.10.10.10 1 83 1.2E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS07540 4233005f09a5234bfcc537ca89636f81 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 2.7E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS04695 093199dd86774f0c7fc89f167cb09862 220 Pfam PF14341 PilX N-terminal 13 63 1.8E-11 T 29-03-2018 IPR025746 Type 4 fimbrial biogenesis protein PilX, N-terminal domain CDC59_RS04695 093199dd86774f0c7fc89f167cb09862 220 Pfam PF13681 Type IV pilus assembly protein PilX C-term 110 215 1.3E-16 T 29-03-2018 IPR025205 PilX/PilW C-terminal domain CDC59_RS21840 980c933cc9762cc436782912885cf30b 128 Pfam PF01042 Endoribonuclease L-PSP 20 125 2.2E-23 T 29-03-2018 IPR006175 YjgF/YER057c/UK114 family CDC59_RS21840 980c933cc9762cc436782912885cf30b 128 SUPERFAMILY SSF55298 17 126 2.67E-34 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CDC59_RS21840 980c933cc9762cc436782912885cf30b 128 Gene3D G3DSA:3.30.1330.40 16 128 1.6E-30 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CDC59_RS17120 f77c787f61b68d3a86ea0869c1bedd36 636 SMART SM00267 186 357 2.8E-72 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS17120 f77c787f61b68d3a86ea0869c1bedd36 636 SMART SM00091 52 117 4.3E-4 T 29-03-2018 IPR000014 PAS domain CDC59_RS17120 f77c787f61b68d3a86ea0869c1bedd36 636 Gene3D G3DSA:3.20.20.450 366 624 3.2E-98 T 29-03-2018 IPR001633 EAL domain CDC59_RS17120 f77c787f61b68d3a86ea0869c1bedd36 636 Pfam PF08448 PAS fold 59 162 3.0E-11 T 29-03-2018 IPR013656 PAS fold-4 CDC59_RS17120 f77c787f61b68d3a86ea0869c1bedd36 636 Gene3D G3DSA:3.30.70.270 195 365 7.1E-67 T 29-03-2018 CDC59_RS17120 f77c787f61b68d3a86ea0869c1bedd36 636 SUPERFAMILY SSF141868 372 621 2.75E-88 T 29-03-2018 IPR001633 EAL domain CDC59_RS17120 f77c787f61b68d3a86ea0869c1bedd36 636 Gene3D G3DSA:3.30.450.20 50 194 5.8E-22 T 29-03-2018 CDC59_RS17120 f77c787f61b68d3a86ea0869c1bedd36 636 Pfam PF00990 Diguanylate cyclase, GGDEF domain 197 353 1.7E-52 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS17120 f77c787f61b68d3a86ea0869c1bedd36 636 SUPERFAMILY SSF55073 202 358 2.9E-55 T 29-03-2018 IPR029787 Nucleotide cyclase CDC59_RS17120 f77c787f61b68d3a86ea0869c1bedd36 636 SUPERFAMILY SSF55785 56 158 2.62E-13 T 29-03-2018 IPR000014 PAS domain CDC59_RS17120 f77c787f61b68d3a86ea0869c1bedd36 636 Pfam PF00563 EAL domain 375 608 1.2E-73 T 29-03-2018 IPR001633 EAL domain CDC59_RS17120 f77c787f61b68d3a86ea0869c1bedd36 636 SMART SM00052 367 613 2.1E-112 T 29-03-2018 IPR001633 EAL domain CDC59_RS17120 f77c787f61b68d3a86ea0869c1bedd36 636 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 194 355 1.3E-46 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS14550 53dc284d2bf93a8b0ada48ca530fa24c 324 SUPERFAMILY SSF52440 1 121 1.29E-41 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CDC59_RS14550 53dc284d2bf93a8b0ada48ca530fa24c 324 Gene3D G3DSA:3.30.470.20 191 299 1.8E-15 T 29-03-2018 CDC59_RS14550 53dc284d2bf93a8b0ada48ca530fa24c 324 Gene3D G3DSA:3.30.1490.20 137 190 6.5E-22 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CDC59_RS14550 53dc284d2bf93a8b0ada48ca530fa24c 324 Pfam PF02955 Prokaryotic glutathione synthetase, ATP-grasp domain 123 296 1.8E-73 T 29-03-2018 IPR004218 Prokaryotic glutathione synthetase, ATP-binding GO:0004363|GO:0005524|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 CDC59_RS14550 53dc284d2bf93a8b0ada48ca530fa24c 324 TIGRFAM TIGR01380 glut_syn: glutathione synthase 1 311 2.2E-123 T 29-03-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 CDC59_RS14550 53dc284d2bf93a8b0ada48ca530fa24c 324 Pfam PF02951 Prokaryotic glutathione synthetase, N-terminal domain 1 119 1.6E-44 T 29-03-2018 IPR004215 Prokaryotic glutathione synthetase, N-terminal GO:0004363|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 CDC59_RS14550 53dc284d2bf93a8b0ada48ca530fa24c 324 SUPERFAMILY SSF56059 123 310 1.31E-55 T 29-03-2018 CDC59_RS14550 53dc284d2bf93a8b0ada48ca530fa24c 324 Hamap MF_00162 Glutathione synthetase [gshB]. 1 315 161.252 T 29-03-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 CDC59_RS14550 53dc284d2bf93a8b0ada48ca530fa24c 324 Gene3D G3DSA:3.40.50.20 1 128 1.7E-48 T 29-03-2018 CDC59_RS19250 9b28914d870ac3236fedfe072643ea82 342 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 317 333 7.8E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CDC59_RS19250 9b28914d870ac3236fedfe072643ea82 342 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 302 317 7.8E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CDC59_RS19250 9b28914d870ac3236fedfe072643ea82 342 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 25 207 6.6E-42 T 29-03-2018 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal CDC59_RS19250 9b28914d870ac3236fedfe072643ea82 342 Pfam PF12833 Helix-turn-helix domain 258 333 9.2E-16 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CDC59_RS19250 9b28914d870ac3236fedfe072643ea82 342 SUPERFAMILY SSF46689 286 333 2.78E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS19250 9b28914d870ac3236fedfe072643ea82 342 SMART SM00342 250 333 7.4E-17 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CDC59_RS19250 9b28914d870ac3236fedfe072643ea82 342 Gene3D G3DSA:1.10.10.60 289 338 1.5E-14 T 29-03-2018 CDC59_RS08965 643cf7903f56200b5f97c5824ebe6b46 175 Pfam PF00583 Acetyltransferase (GNAT) family 44 140 5.2E-13 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CDC59_RS08965 643cf7903f56200b5f97c5824ebe6b46 175 SUPERFAMILY SSF55729 25 165 5.23E-32 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDC59_RS08965 643cf7903f56200b5f97c5824ebe6b46 175 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 31 163 8.4E-35 T 29-03-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 CDC59_RS08965 643cf7903f56200b5f97c5824ebe6b46 175 Gene3D G3DSA:3.40.630.30 22 173 7.3E-31 T 29-03-2018 CDC59_RS16895 65896ae14fd5a50eb4650ec8471e7969 784 SUPERFAMILY SSF81653 274 361 2.35E-20 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CDC59_RS16895 65896ae14fd5a50eb4650ec8471e7969 784 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 211 779 4.7E-158 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CDC59_RS16895 65896ae14fd5a50eb4650ec8471e7969 784 Gene3D G3DSA:3.40.50.1000 604 744 1.8E-34 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS16895 65896ae14fd5a50eb4650ec8471e7969 784 SUPERFAMILY SSF55008 68 132 1.11E-7 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CDC59_RS16895 65896ae14fd5a50eb4650ec8471e7969 784 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 465 471 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CDC59_RS16895 65896ae14fd5a50eb4650ec8471e7969 784 Gene3D G3DSA:3.30.70.100 67 138 3.6E-6 T 29-03-2018 CDC59_RS16895 65896ae14fd5a50eb4650ec8471e7969 784 Gene3D G3DSA:3.40.1110.10 487 603 1.1E-20 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CDC59_RS16895 65896ae14fd5a50eb4650ec8471e7969 784 Pfam PF00122 E1-E2 ATPase 272 443 2.5E-46 T 29-03-2018 CDC59_RS16895 65896ae14fd5a50eb4650ec8471e7969 784 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 234 482 2.6E-33 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CDC59_RS16895 65896ae14fd5a50eb4650ec8471e7969 784 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 577 756 1.2E-34 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CDC59_RS16895 65896ae14fd5a50eb4650ec8471e7969 784 SUPERFAMILY SSF81665 202 265 1.1E-16 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CDC59_RS16895 65896ae14fd5a50eb4650ec8471e7969 784 SUPERFAMILY SSF81665 363 454 1.1E-16 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CDC59_RS16895 65896ae14fd5a50eb4650ec8471e7969 784 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 312 326 5.4E-24 T 29-03-2018 CDC59_RS16895 65896ae14fd5a50eb4650ec8471e7969 784 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 601 612 5.4E-24 T 29-03-2018 CDC59_RS16895 65896ae14fd5a50eb4650ec8471e7969 784 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 463 477 5.4E-24 T 29-03-2018 CDC59_RS16895 65896ae14fd5a50eb4650ec8471e7969 784 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 676 695 5.4E-24 T 29-03-2018 CDC59_RS16895 65896ae14fd5a50eb4650ec8471e7969 784 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 623 633 5.4E-24 T 29-03-2018 CDC59_RS16895 65896ae14fd5a50eb4650ec8471e7969 784 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 700 712 5.4E-24 T 29-03-2018 CDC59_RS16895 65896ae14fd5a50eb4650ec8471e7969 784 Pfam PF00702 haloacid dehalogenase-like hydrolase 460 690 5.4E-30 T 29-03-2018 CDC59_RS16895 65896ae14fd5a50eb4650ec8471e7969 784 Gene3D G3DSA:1.20.1110.10 181 477 3.2E-32 T 29-03-2018 CDC59_RS16895 65896ae14fd5a50eb4650ec8471e7969 784 SUPERFAMILY SSF56784 462 481 1.04E-51 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS16895 65896ae14fd5a50eb4650ec8471e7969 784 SUPERFAMILY SSF56784 534 776 1.04E-51 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS15930 8bc1cd2ebc7bfe13168aa4b4dbf3d874 445 SUPERFAMILY SSF52540 4 441 2.08E-87 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS15930 8bc1cd2ebc7bfe13168aa4b4dbf3d874 445 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 54 105 2.0E-6 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CDC59_RS15930 8bc1cd2ebc7bfe13168aa4b4dbf3d874 445 Gene3D G3DSA:3.40.50.300 8 97 0.0014 T 29-03-2018 CDC59_RS15930 8bc1cd2ebc7bfe13168aa4b4dbf3d874 445 SMART SM00382 50 334 2.2E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS15930 8bc1cd2ebc7bfe13168aa4b4dbf3d874 445 Pfam PF07724 AAA domain (Cdc48 subfamily) 186 331 4.7E-40 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CDC59_RS15930 8bc1cd2ebc7bfe13168aa4b4dbf3d874 445 Gene3D G3DSA:1.10.8.10 201 243 3.1E-14 T 29-03-2018 CDC59_RS15930 8bc1cd2ebc7bfe13168aa4b4dbf3d874 445 SMART SM01086 337 436 1.8E-17 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CDC59_RS15930 8bc1cd2ebc7bfe13168aa4b4dbf3d874 445 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 5 445 3.4E-203 T 29-03-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 CDC59_RS15930 8bc1cd2ebc7bfe13168aa4b4dbf3d874 445 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 2 445 43.597 T 29-03-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 CDC59_RS15930 8bc1cd2ebc7bfe13168aa4b4dbf3d874 445 Gene3D G3DSA:1.10.8.10 112 200 1.1E-27 T 29-03-2018 CDC59_RS15930 8bc1cd2ebc7bfe13168aa4b4dbf3d874 445 Gene3D G3DSA:1.10.8.60 337 433 1.6E-26 T 29-03-2018 CDC59_RS08505 b69b85e068b5721c11d5727072449dba 226 Gene3D G3DSA:1.10.760.10 42 214 5.6E-23 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS08505 b69b85e068b5721c11d5727072449dba 226 SUPERFAMILY SSF46626 22 202 4.3E-27 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS08505 b69b85e068b5721c11d5727072449dba 226 TIGRFAM TIGR00781 ccoO: cytochrome c oxidase, cbb3-type, subunit II 11 188 6.6E-85 T 29-03-2018 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO CDC59_RS08505 b69b85e068b5721c11d5727072449dba 226 Pfam PF02433 Cytochrome C oxidase, mono-heme subunit/FixO 11 194 6.5E-83 T 29-03-2018 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO CDC59_RS19580 8625a082036b1fa96381842e18c07742 565 SUPERFAMILY SSF53756 80 525 4.9E-129 T 29-03-2018 CDC59_RS19580 8625a082036b1fa96381842e18c07742 565 Gene3D G3DSA:3.40.50.2000 77 317 1.5E-51 T 29-03-2018 CDC59_RS19580 8625a082036b1fa96381842e18c07742 565 Pfam PF00982 Glycosyltransferase family 20 94 524 8.0E-110 T 29-03-2018 IPR001830 Glycosyl transferase, family 20 GO:0003824|GO:0005992 CDC59_RS19580 8625a082036b1fa96381842e18c07742 565 Gene3D G3DSA:3.40.50.2000 318 509 6.1E-39 T 29-03-2018 CDC59_RS21000 54a84ae9a591cbe24aec5087e7a0c104 307 SUPERFAMILY SSF161098 100 286 2.49E-18 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS21000 54a84ae9a591cbe24aec5087e7a0c104 307 Gene3D G3DSA:1.10.3720.10 25 295 9.4E-33 T 29-03-2018 CDC59_RS21000 54a84ae9a591cbe24aec5087e7a0c104 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 122 295 4.5E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS12990 a602eba6c6cfaae8b5be71f4cb31dee5 308 Gene3D G3DSA:1.10.443.10 126 301 4.4E-48 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CDC59_RS12990 a602eba6c6cfaae8b5be71f4cb31dee5 308 SUPERFAMILY SSF56349 116 306 6.47E-58 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CDC59_RS12990 a602eba6c6cfaae8b5be71f4cb31dee5 308 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 20 307 3.2E-111 T 29-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 CDC59_RS12990 a602eba6c6cfaae8b5be71f4cb31dee5 308 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 19 100 9.0E-18 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CDC59_RS12990 a602eba6c6cfaae8b5be71f4cb31dee5 308 Gene3D G3DSA:1.10.150.130 13 125 2.2E-20 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal CDC59_RS12990 a602eba6c6cfaae8b5be71f4cb31dee5 308 Pfam PF00589 Phage integrase family 122 293 2.7E-50 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CDC59_RS12990 a602eba6c6cfaae8b5be71f4cb31dee5 308 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 17 308 56.149 T 29-03-2018 IPR023009 Tyrosine recombinase XerC/XerD CDC59_RS12990 a602eba6c6cfaae8b5be71f4cb31dee5 308 SUPERFAMILY SSF47823 16 110 9.22E-30 T 29-03-2018 IPR010998 Integrase, Lambda-type, N-terminal CDC59_RS12990 a602eba6c6cfaae8b5be71f4cb31dee5 308 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 15 308 62.825 T 29-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 CDC59_RS06780 16a48da4fc713e6ffabc865c881a4b51 457 Gene3D G3DSA:3.30.2290.10 3 239 1.4E-60 T 29-03-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal domain CDC59_RS06780 16a48da4fc713e6ffabc865c881a4b51 457 Pfam PF01523 Putative modulator of DNA gyrase 43 330 9.6E-62 T 29-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 CDC59_RS06780 16a48da4fc713e6ffabc865c881a4b51 457 SUPERFAMILY SSF111283 18 457 1.57E-125 T 29-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 CDC59_RS15125 ea3c5f202e4f83309c5beac8bd5ad019 1099 Pfam PF03308 ArgK protein 178 410 2.6E-42 T 29-03-2018 CDC59_RS15125 ea3c5f202e4f83309c5beac8bd5ad019 1099 Gene3D G3DSA:3.20.20.240 544 1095 6.3E-193 T 29-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CDC59_RS15125 ea3c5f202e4f83309c5beac8bd5ad019 1099 Pfam PF01642 Methylmalonyl-CoA mutase 558 1093 2.0E-145 T 29-03-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CDC59_RS15125 ea3c5f202e4f83309c5beac8bd5ad019 1099 Pfam PF02310 B12 binding domain 26 129 8.3E-12 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CDC59_RS15125 ea3c5f202e4f83309c5beac8bd5ad019 1099 SUPERFAMILY SSF51703 512 1095 1.07E-149 T 29-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CDC59_RS15125 ea3c5f202e4f83309c5beac8bd5ad019 1099 SUPERFAMILY SSF52540 139 416 5.68E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS15125 ea3c5f202e4f83309c5beac8bd5ad019 1099 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 730 1098 3.6E-91 T 29-03-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CDC59_RS15125 ea3c5f202e4f83309c5beac8bd5ad019 1099 Hamap MF_02050 Fused isobutyryl-CoA mutase [icmF]. 24 1099 16.94 T 29-03-2018 IPR033669 Fused isobutyryl-CoA mutase GO:0003924|GO:0005525|GO:0006637|GO:0031419|GO:0034784|GO:0047727 CDC59_RS15125 ea3c5f202e4f83309c5beac8bd5ad019 1099 Gene3D G3DSA:3.40.50.280 21 161 7.4E-25 T 29-03-2018 CDC59_RS15125 ea3c5f202e4f83309c5beac8bd5ad019 1099 SUPERFAMILY SSF52242 23 156 8.24E-41 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CDC59_RS15125 ea3c5f202e4f83309c5beac8bd5ad019 1099 Gene3D G3DSA:1.20.5.170 162 197 3.4E-5 T 29-03-2018 CDC59_RS15125 ea3c5f202e4f83309c5beac8bd5ad019 1099 Gene3D G3DSA:3.40.50.300 206 415 5.0E-34 T 29-03-2018 CDC59_RS18155 72c7ba7880e08f835f1ed138c599b245 345 SUPERFAMILY SSF51197 17 322 5.97E-61 T 29-03-2018 CDC59_RS18155 72c7ba7880e08f835f1ed138c599b245 345 Gene3D G3DSA:2.60.120.330 7 326 6.6E-60 T 29-03-2018 IPR027443 Isopenicillin N synthase-like CDC59_RS18155 72c7ba7880e08f835f1ed138c599b245 345 Pfam PF14226 non-haem dioxygenase in morphine synthesis N-terminal 16 122 1.1E-13 T 29-03-2018 IPR026992 Non-haem dioxygenase N-terminal domain CDC59_RS18155 72c7ba7880e08f835f1ed138c599b245 345 Pfam PF03171 2OG-Fe(II) oxygenase superfamily 168 288 4.8E-21 T 29-03-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 CDC59_RS05945 9aac7c894c336c37483dc232692e644f 284 SUPERFAMILY SSF53850 15 265 5.65E-63 T 29-03-2018 CDC59_RS05945 9aac7c894c336c37483dc232692e644f 284 Gene3D G3DSA:3.40.190.10 143 225 3.9E-20 T 29-03-2018 CDC59_RS05945 9aac7c894c336c37483dc232692e644f 284 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 43 264 2.5E-57 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CDC59_RS05945 9aac7c894c336c37483dc232692e644f 284 SMART SM00062 42 266 1.3E-59 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CDC59_RS05945 9aac7c894c336c37483dc232692e644f 284 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 67 80 - T 29-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 CDC59_RS05945 9aac7c894c336c37483dc232692e644f 284 Gene3D G3DSA:3.40.190.10 32 142 1.1E-28 T 29-03-2018 CDC59_RS07175 9e1c972f4c1c2c9228156f0f83d3e445 112 SUPERFAMILY SSF54292 4 108 1.52E-32 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CDC59_RS07175 9e1c972f4c1c2c9228156f0f83d3e445 112 Gene3D G3DSA:3.10.20.30 9 112 3.5E-30 T 29-03-2018 IPR012675 Beta-grasp domain CDC59_RS07175 9e1c972f4c1c2c9228156f0f83d3e445 112 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 14 91 2.8E-12 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CDC59_RS07175 9e1c972f4c1c2c9228156f0f83d3e445 112 TIGRFAM TIGR02007 fdx_isc: ferredoxin, 2Fe-2S type, ISC system 2 110 9.0E-62 T 29-03-2018 IPR011536 Ferredoxin 2Fe-2S type, proteobacteria GO:0009055|GO:0051537 CDC59_RS07175 9e1c972f4c1c2c9228156f0f83d3e445 112 ProSitePatterns PS00814 Adrenodoxin family, iron-sulfur binding region signature. 42 52 - T 29-03-2018 IPR018298 Adrenodoxin, iron-sulphur binding site GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 CDC59_RS07175 9e1c972f4c1c2c9228156f0f83d3e445 112 PRINTS PR00355 Adrenodoxin signature 42 52 1.0E-9 T 29-03-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 CDC59_RS07175 9e1c972f4c1c2c9228156f0f83d3e445 112 PRINTS PR00355 Adrenodoxin signature 83 91 1.0E-9 T 29-03-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 CDC59_RS07175 9e1c972f4c1c2c9228156f0f83d3e445 112 PRINTS PR00355 Adrenodoxin signature 60 74 1.0E-9 T 29-03-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 CDC59_RS18240 bcb6f67777034088726d568d760dd381 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 157 210 2.5E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS18240 bcb6f67777034088726d568d760dd381 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 171 2.1E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS18240 bcb6f67777034088726d568d760dd381 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 187 2.1E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS18240 bcb6f67777034088726d568d760dd381 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 187 199 2.1E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS18240 bcb6f67777034088726d568d760dd381 218 SMART SM00421 154 211 5.6E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS18240 bcb6f67777034088726d568d760dd381 218 Gene3D G3DSA:1.10.10.10 36 215 7.4E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS18240 bcb6f67777034088726d568d760dd381 218 SUPERFAMILY SSF46894 145 212 3.4E-15 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CDC59_RS15060 96c8ee6b81cc008d7e67df941d830790 327 Gene3D G3DSA:3.20.20.70 10 322 4.4E-36 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS15060 96c8ee6b81cc008d7e67df941d830790 327 SUPERFAMILY SSF51412 12 308 4.94E-57 T 29-03-2018 CDC59_RS15060 96c8ee6b81cc008d7e67df941d830790 327 Pfam PF03060 Nitronate monooxygenase 90 311 3.4E-22 T 29-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CDC59_RS20420 6dade65461416dc925aecebb5dc7cf0a 331 Gene3D G3DSA:3.40.50.720 115 292 9.8E-54 T 29-03-2018 CDC59_RS20420 6dade65461416dc925aecebb5dc7cf0a 331 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 150 178 - T 29-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 CDC59_RS20420 6dade65461416dc925aecebb5dc7cf0a 331 Gene3D G3DSA:3.40.50.720 1 114 8.9E-36 T 29-03-2018 CDC59_RS20420 6dade65461416dc925aecebb5dc7cf0a 331 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 109 289 1.7E-57 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CDC59_RS20420 6dade65461416dc925aecebb5dc7cf0a 331 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 5 313 7.4E-27 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CDC59_RS20420 6dade65461416dc925aecebb5dc7cf0a 331 SUPERFAMILY SSF51735 101 290 1.11E-55 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS20420 6dade65461416dc925aecebb5dc7cf0a 331 SUPERFAMILY SSF52283 1 135 6.24E-38 T 29-03-2018 CDC59_RS09205 374e29cf723434ad19c301ff18ca5ab3 164 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 15 154 2.3E-60 T 29-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CDC59_RS09205 374e29cf723434ad19c301ff18ca5ab3 164 Gene3D G3DSA:3.10.129.10 2 162 6.4E-55 T 29-03-2018 CDC59_RS09205 374e29cf723434ad19c301ff18ca5ab3 164 SUPERFAMILY SSF54637 15 158 2.49E-48 T 29-03-2018 IPR029069 HotDog domain CDC59_RS09205 374e29cf723434ad19c301ff18ca5ab3 164 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 15 157 35.556 T 29-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CDC59_RS09205 374e29cf723434ad19c301ff18ca5ab3 164 Pfam PF07977 FabA-like domain 24 150 1.2E-36 T 29-03-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CDC59_RS07520 f3850b1bb425810dec5640d94fcf1c19 418 Gene3D G3DSA:2.102.10.10 37 156 2.7E-22 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CDC59_RS07520 f3850b1bb425810dec5640d94fcf1c19 418 Pfam PF00355 Rieske [2Fe-2S] domain 44 129 8.5E-19 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CDC59_RS07520 f3850b1bb425810dec5640d94fcf1c19 418 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 192 214 1.1E-31 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CDC59_RS07520 f3850b1bb425810dec5640d94fcf1c19 418 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 153 179 1.1E-31 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CDC59_RS07520 f3850b1bb425810dec5640d94fcf1c19 418 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 101 121 1.1E-31 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CDC59_RS07520 f3850b1bb425810dec5640d94fcf1c19 418 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 28 53 1.1E-31 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CDC59_RS07520 f3850b1bb425810dec5640d94fcf1c19 418 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 59 74 1.1E-31 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CDC59_RS07520 f3850b1bb425810dec5640d94fcf1c19 418 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 80 100 1.1E-31 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CDC59_RS07520 f3850b1bb425810dec5640d94fcf1c19 418 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 203 417 5.7E-18 T 29-03-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 CDC59_RS07520 f3850b1bb425810dec5640d94fcf1c19 418 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 87 110 - T 29-03-2018 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0016705|GO:0051537|GO:0055114 CDC59_RS07520 f3850b1bb425810dec5640d94fcf1c19 418 Gene3D G3DSA:3.90.380.10 157 418 8.1E-49 T 29-03-2018 CDC59_RS07520 f3850b1bb425810dec5640d94fcf1c19 418 SUPERFAMILY SSF50022 10 168 1.96E-45 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CDC59_RS07520 f3850b1bb425810dec5640d94fcf1c19 418 SUPERFAMILY SSF55961 178 416 4.71E-56 T 29-03-2018 CDC59_RS15470 ec7679b823382ea7e5e57b2a5f02bc2f 292 Gene3D G3DSA:3.10.310.10 127 270 9.4E-50 T 29-03-2018 CDC59_RS15470 ec7679b823382ea7e5e57b2a5f02bc2f 292 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 3 283 39.317 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CDC59_RS15470 ec7679b823382ea7e5e57b2a5f02bc2f 292 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 66 80 - T 29-03-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CDC59_RS15470 ec7679b823382ea7e5e57b2a5f02bc2f 292 SUPERFAMILY SSF54506 3 283 4.92E-52 T 29-03-2018 CDC59_RS15470 ec7679b823382ea7e5e57b2a5f02bc2f 292 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 4 281 4.4E-86 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CDC59_RS15470 ec7679b823382ea7e5e57b2a5f02bc2f 292 Pfam PF01678 Diaminopimelate epimerase 5 125 1.6E-33 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CDC59_RS15470 ec7679b823382ea7e5e57b2a5f02bc2f 292 Pfam PF01678 Diaminopimelate epimerase 161 275 9.1E-27 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CDC59_RS15470 ec7679b823382ea7e5e57b2a5f02bc2f 292 Gene3D G3DSA:3.10.310.10 1 126 9.1E-51 T 29-03-2018 CDC59_RS12595 0e5b1042e398def7340d3b857b5991c8 396 Pfam PF01610 Transposase 273 395 1.2E-7 T 29-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CDC59_RS12595 0e5b1042e398def7340d3b857b5991c8 396 Pfam PF00487 Fatty acid desaturase 18 239 3.1E-14 T 29-03-2018 IPR005804 Fatty acid desaturase domain GO:0006629 CDC59_RS09920 5a60d63fbc302c9fdf1312372f37189b 221 SUPERFAMILY SSF52317 7 204 1.04E-35 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CDC59_RS09920 5a60d63fbc302c9fdf1312372f37189b 221 Gene3D G3DSA:3.40.50.880 3 217 2.4E-42 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CDC59_RS09920 5a60d63fbc302c9fdf1312372f37189b 221 Pfam PF01965 DJ-1/PfpI family 11 184 4.1E-15 T 29-03-2018 IPR002818 DJ-1/PfpI CDC59_RS22650 6365c23f5a0524fe21fcd9dabfdbf39e 110 SUPERFAMILY SSF103481 10 107 1.19E-5 T 29-03-2018 CDC59_RS22650 6365c23f5a0524fe21fcd9dabfdbf39e 110 Hamap MF_00010 UPF0060 membrane protein YnfA [ynfA]. 4 108 23.431 T 29-03-2018 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 CDC59_RS22650 6365c23f5a0524fe21fcd9dabfdbf39e 110 Pfam PF02694 Uncharacterised BCR, YnfA/UPF0060 family 4 105 1.5E-36 T 29-03-2018 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 CDC59_RS20250 29dad818c8289e0895acb78418791eb0 567 Pfam PF03958 Bacterial type II/III secretion system short domain 100 160 1.5E-9 T 29-03-2018 IPR005644 NolW-like CDC59_RS20250 29dad818c8289e0895acb78418791eb0 567 Pfam PF03958 Bacterial type II/III secretion system short domain 168 321 2.6E-21 T 29-03-2018 IPR005644 NolW-like CDC59_RS20250 29dad818c8289e0895acb78418791eb0 567 TIGRFAM TIGR02516 type_III_yscC: type III secretion outer membrane pore, YscC/HrcC family 282 566 2.7E-96 T 29-03-2018 IPR003522 Type III secretion system outer membrane pore YscC/HrcC GO:0009306 CDC59_RS20250 29dad818c8289e0895acb78418791eb0 567 PRINTS PR01337 Type III secretion system outer membrane G protein family signature 180 197 6.9E-29 T 29-03-2018 IPR003522 Type III secretion system outer membrane pore YscC/HrcC GO:0009306 CDC59_RS20250 29dad818c8289e0895acb78418791eb0 567 PRINTS PR01337 Type III secretion system outer membrane G protein family signature 455 470 6.9E-29 T 29-03-2018 IPR003522 Type III secretion system outer membrane pore YscC/HrcC GO:0009306 CDC59_RS20250 29dad818c8289e0895acb78418791eb0 567 PRINTS PR01337 Type III secretion system outer membrane G protein family signature 421 440 6.9E-29 T 29-03-2018 IPR003522 Type III secretion system outer membrane pore YscC/HrcC GO:0009306 CDC59_RS20250 29dad818c8289e0895acb78418791eb0 567 PRINTS PR01337 Type III secretion system outer membrane G protein family signature 544 563 6.9E-29 T 29-03-2018 IPR003522 Type III secretion system outer membrane pore YscC/HrcC GO:0009306 CDC59_RS20250 29dad818c8289e0895acb78418791eb0 567 PRINTS PR01337 Type III secretion system outer membrane G protein family signature 324 344 6.9E-29 T 29-03-2018 IPR003522 Type III secretion system outer membrane pore YscC/HrcC GO:0009306 CDC59_RS20250 29dad818c8289e0895acb78418791eb0 567 Pfam PF00263 Bacterial type II and III secretion system protein 408 565 1.4E-38 T 29-03-2018 IPR004846 Type II/III secretion system GO:0009306 CDC59_RS20250 29dad818c8289e0895acb78418791eb0 567 ProSitePatterns PS00875 Bacterial type II secretion system protein D signature. 511 544 - T 29-03-2018 IPR004845 Type II secretion system GspD, conserved site GO:0008565 CDC59_RS17515 ef287ebc1f04df9d1d09b498cc9d26fe 298 Gene3D G3DSA:1.10.10.10 2 67 7.1E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS17515 ef287ebc1f04df9d1d09b498cc9d26fe 298 Pfam PF07729 FCD domain 160 283 1.5E-14 T 29-03-2018 IPR011711 GntR, C-terminal CDC59_RS17515 ef287ebc1f04df9d1d09b498cc9d26fe 298 Gene3D G3DSA:1.20.120.530 152 297 8.5E-22 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CDC59_RS17515 ef287ebc1f04df9d1d09b498cc9d26fe 298 Gene3D G3DSA:1.10.10.10 80 151 7.1E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS17515 ef287ebc1f04df9d1d09b498cc9d26fe 298 SMART SM00895 159 284 2.1E-10 T 29-03-2018 IPR011711 GntR, C-terminal CDC59_RS17515 ef287ebc1f04df9d1d09b498cc9d26fe 298 SMART SM00345 7 65 3.8E-11 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDC59_RS17515 ef287ebc1f04df9d1d09b498cc9d26fe 298 SUPERFAMILY SSF46785 7 67 3.0E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS17515 ef287ebc1f04df9d1d09b498cc9d26fe 298 SUPERFAMILY SSF48008 154 290 7.59E-20 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CDC59_RS17515 ef287ebc1f04df9d1d09b498cc9d26fe 298 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 65 2.6E-11 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDC59_RS23940 0fe954e9ce5a3083c0c76e4869171c4a 500 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 6 50 8.2E-15 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CDC59_RS23940 0fe954e9ce5a3083c0c76e4869171c4a 500 Gene3D G3DSA:1.10.10.10 188 265 0.32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS23940 0fe954e9ce5a3083c0c76e4869171c4a 500 Pfam PF04552 Sigma-54, DNA binding domain 343 498 1.9E-60 T 29-03-2018 IPR007634 RNA polymerase sigma factor 54, DNA-binding CDC59_RS23940 0fe954e9ce5a3083c0c76e4869171c4a 500 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 11 498 2.0E-130 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CDC59_RS23940 0fe954e9ce5a3083c0c76e4869171c4a 500 PRINTS PR00045 Sigma-54 factor signature 207 224 2.3E-27 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CDC59_RS23940 0fe954e9ce5a3083c0c76e4869171c4a 500 PRINTS PR00045 Sigma-54 factor signature 400 412 2.3E-27 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CDC59_RS23940 0fe954e9ce5a3083c0c76e4869171c4a 500 PRINTS PR00045 Sigma-54 factor signature 416 427 2.3E-27 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CDC59_RS23940 0fe954e9ce5a3083c0c76e4869171c4a 500 PRINTS PR00045 Sigma-54 factor signature 474 492 2.3E-27 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CDC59_RS23940 0fe954e9ce5a3083c0c76e4869171c4a 500 Pfam PF04963 Sigma-54 factor, core binding domain 132 328 7.4E-53 T 29-03-2018 IPR007046 RNA polymerase sigma factor 54, core-binding GO:0003677|GO:0006352 CDC59_RS23940 0fe954e9ce5a3083c0c76e4869171c4a 500 Gene3D G3DSA:1.10.10.10 346 437 4.1E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS23940 0fe954e9ce5a3083c0c76e4869171c4a 500 PIRSF PIRSF000774 1 500 4.1E-148 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CDC59_RS23940 0fe954e9ce5a3083c0c76e4869171c4a 500 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 479 486 - T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CDC59_RS23940 0fe954e9ce5a3083c0c76e4869171c4a 500 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 388 407 - T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CDC59_RS08350 3fb30441bf264f767e14cc5e2d68443c 264 Pfam PF04962 KduI/IolB family 6 260 1.3E-108 T 29-03-2018 IPR021120 KduI/IolB isomerase GO:0016861 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 CDC59_RS08350 3fb30441bf264f767e14cc5e2d68443c 264 Gene3D G3DSA:2.60.120.10 120 264 3.6E-57 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CDC59_RS08350 3fb30441bf264f767e14cc5e2d68443c 264 SUPERFAMILY SSF51182 15 249 2.25E-67 T 29-03-2018 IPR011051 RmlC-like cupin domain CDC59_RS08350 3fb30441bf264f767e14cc5e2d68443c 264 PIRSF PIRSF036628 1 264 1.8E-105 T 29-03-2018 IPR024203 5-deoxy-glucuronate isomerase, IolB GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30 CDC59_RS08350 3fb30441bf264f767e14cc5e2d68443c 264 TIGRFAM TIGR04378 myo_inos_iolB: 5-deoxy-glucuronate isomerase 16 260 2.4E-98 T 29-03-2018 IPR024203 5-deoxy-glucuronate isomerase, IolB GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30 CDC59_RS08350 3fb30441bf264f767e14cc5e2d68443c 264 Gene3D G3DSA:2.60.120.10 14 119 8.4E-35 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CDC59_RS03695 00e7b01d95b907226f7738165e9ac675 457 PRINTS PR00149 Fumarate lyase superfamily signature 163 181 1.7E-18 T 29-03-2018 IPR000362 Fumarate lyase family CDC59_RS03695 00e7b01d95b907226f7738165e9ac675 457 PRINTS PR00149 Fumarate lyase superfamily signature 252 279 1.7E-18 T 29-03-2018 IPR000362 Fumarate lyase family CDC59_RS03695 00e7b01d95b907226f7738165e9ac675 457 PRINTS PR00149 Fumarate lyase superfamily signature 117 135 1.7E-18 T 29-03-2018 IPR000362 Fumarate lyase family CDC59_RS03695 00e7b01d95b907226f7738165e9ac675 457 PRINTS PR00149 Fumarate lyase superfamily signature 295 311 1.7E-18 T 29-03-2018 IPR000362 Fumarate lyase family CDC59_RS03695 00e7b01d95b907226f7738165e9ac675 457 Pfam PF00206 Lyase 15 313 4.2E-60 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal CDC59_RS03695 00e7b01d95b907226f7738165e9ac675 457 Pfam PF08328 Adenylosuccinate lyase C-terminal 332 446 7.2E-50 T 29-03-2018 IPR013539 Adenylosuccinate lyase PurB, C-terminal GO:0004018|GO:0006188 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234 CDC59_RS03695 00e7b01d95b907226f7738165e9ac675 457 Gene3D G3DSA:1.20.200.10 118 391 1.2E-85 T 29-03-2018 CDC59_RS03695 00e7b01d95b907226f7738165e9ac675 457 Gene3D G3DSA:1.10.40.30 392 446 3.3E-29 T 29-03-2018 CDC59_RS03695 00e7b01d95b907226f7738165e9ac675 457 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 13 455 5.3E-126 T 29-03-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CDC59_RS03695 00e7b01d95b907226f7738165e9ac675 457 Gene3D G3DSA:1.10.275.10 1 117 2.5E-41 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal CDC59_RS03695 00e7b01d95b907226f7738165e9ac675 457 ProSitePatterns PS00163 Fumarate lyases signature. 295 304 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CDC59_RS03695 00e7b01d95b907226f7738165e9ac675 457 SUPERFAMILY SSF48557 4 447 5.18E-105 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 CDC59_RS02670 d62f8459c3487b59fc87de4af3b3748e 375 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 187 199 2.2E-6 T 29-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 CDC59_RS02670 d62f8459c3487b59fc87de4af3b3748e 375 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 305 322 2.2E-6 T 29-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 CDC59_RS02670 d62f8459c3487b59fc87de4af3b3748e 375 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 100 110 2.2E-6 T 29-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 CDC59_RS02670 d62f8459c3487b59fc87de4af3b3748e 375 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 56 67 2.2E-6 T 29-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 CDC59_RS02670 d62f8459c3487b59fc87de4af3b3748e 375 Gene3D G3DSA:2.40.160.10 9 375 1.3E-76 T 29-03-2018 CDC59_RS02670 d62f8459c3487b59fc87de4af3b3748e 375 PRINTS PR00184 Neisseria sp. porin signature 302 326 4.3E-5 T 29-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 CDC59_RS02670 d62f8459c3487b59fc87de4af3b3748e 375 PRINTS PR00184 Neisseria sp. porin signature 58 83 4.3E-5 T 29-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 CDC59_RS02670 d62f8459c3487b59fc87de4af3b3748e 375 SUPERFAMILY SSF56935 21 375 3.36E-87 T 29-03-2018 CDC59_RS02670 d62f8459c3487b59fc87de4af3b3748e 375 Pfam PF13609 Gram-negative porin 7 329 5.7E-52 T 29-03-2018 CDC59_RS02025 5df88209db46b658e3a548f37715d72d 498 Hamap MF_00186 Glycerol kinase [glpK]. 1 494 56.817 T 29-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 CDC59_RS02025 5df88209db46b658e3a548f37715d72d 498 SUPERFAMILY SSF53067 3 252 1.99E-95 T 29-03-2018 CDC59_RS02025 5df88209db46b658e3a548f37715d72d 498 PIRSF PIRSF000538 1 496 1.4E-174 T 29-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CDC59_RS02025 5df88209db46b658e3a548f37715d72d 498 SUPERFAMILY SSF53067 252 491 8.35E-81 T 29-03-2018 CDC59_RS02025 5df88209db46b658e3a548f37715d72d 498 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 3 249 1.0E-78 T 29-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CDC59_RS02025 5df88209db46b658e3a548f37715d72d 498 Gene3D G3DSA:3.30.420.40 246 494 1.6E-75 T 29-03-2018 CDC59_RS02025 5df88209db46b658e3a548f37715d72d 498 Gene3D G3DSA:3.30.420.40 1 245 2.5E-89 T 29-03-2018 CDC59_RS02025 5df88209db46b658e3a548f37715d72d 498 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 359 379 - T 29-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CDC59_RS02025 5df88209db46b658e3a548f37715d72d 498 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 2 489 3.8E-215 T 29-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 CDC59_RS02025 5df88209db46b658e3a548f37715d72d 498 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 258 447 5.2E-63 T 29-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CDC59_RS02025 5df88209db46b658e3a548f37715d72d 498 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 133 145 - T 29-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CDC59_RS09500 01b644a8ba2306999f654bc0f3380106 175 Gene3D G3DSA:3.10.20.30 2 76 6.5E-25 T 29-03-2018 IPR012675 Beta-grasp domain CDC59_RS09500 01b644a8ba2306999f654bc0f3380106 175 Gene3D G3DSA:1.10.150.120 77 175 1.2E-36 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CDC59_RS09500 01b644a8ba2306999f654bc0f3380106 175 SUPERFAMILY SSF54292 4 80 1.44E-24 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CDC59_RS09500 01b644a8ba2306999f654bc0f3380106 175 SUPERFAMILY SSF47741 86 154 2.36E-33 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CDC59_RS09500 01b644a8ba2306999f654bc0f3380106 175 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 41 49 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CDC59_RS09500 01b644a8ba2306999f654bc0f3380106 175 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 9 61 3.3E-6 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CDC59_RS09500 01b644a8ba2306999f654bc0f3380106 175 Pfam PF01799 [2Fe-2S] binding domain 75 147 4.2E-31 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CDC59_RS04365 8cff2444ebe404c6ac6fd16e106fc9a3 173 Pfam PF04536 TPM domain 27 148 3.7E-9 T 29-03-2018 IPR007621 TPM domain CDC59_RS15655 7e61b029bd7d26da3df25dec49b376ea 474 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 6 466 48.551 T 29-03-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508 CDC59_RS15655 7e61b029bd7d26da3df25dec49b376ea 474 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 10 473 5.0E-145 T 29-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CDC59_RS15655 7e61b029bd7d26da3df25dec49b376ea 474 SUPERFAMILY SSF51735 231 390 3.1E-79 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS15655 7e61b029bd7d26da3df25dec49b376ea 474 Gene3D G3DSA:3.40.50.1480 2 246 1.4E-90 T 29-03-2018 CDC59_RS15655 7e61b029bd7d26da3df25dec49b376ea 474 Gene3D G3DSA:3.40.50.1480 247 447 1.0E-81 T 29-03-2018 CDC59_RS15655 7e61b029bd7d26da3df25dec49b376ea 474 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 11 466 3.2E-183 T 29-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CDC59_RS15655 7e61b029bd7d26da3df25dec49b376ea 474 SMART SM00996 10 473 0.0 T 29-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CDC59_RS15655 7e61b029bd7d26da3df25dec49b376ea 474 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 82 96 - T 29-03-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CDC59_RS15655 7e61b029bd7d26da3df25dec49b376ea 474 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 253 269 - T 29-03-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CDC59_RS15655 7e61b029bd7d26da3df25dec49b376ea 474 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 231 390 3.4E-81 T 29-03-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CDC59_RS15655 7e61b029bd7d26da3df25dec49b376ea 474 PIRSF PIRSF001109 2 474 6.5E-189 T 29-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CDC59_RS15655 7e61b029bd7d26da3df25dec49b376ea 474 SUPERFAMILY SSF52283 9 147 1.98E-112 T 29-03-2018 CDC59_RS15655 7e61b029bd7d26da3df25dec49b376ea 474 SUPERFAMILY SSF52283 183 230 1.98E-112 T 29-03-2018 CDC59_RS15655 7e61b029bd7d26da3df25dec49b376ea 474 SUPERFAMILY SSF52283 391 474 1.98E-112 T 29-03-2018 CDC59_RS15655 7e61b029bd7d26da3df25dec49b376ea 474 SMART SM00997 231 390 5.4E-114 T 29-03-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CDC59_RS03690 febdaad2f498911ff2928fc8e4c9c27c 202 SUPERFAMILY SSF52833 1 100 4.06E-21 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS03690 febdaad2f498911ff2928fc8e4c9c27c 202 Gene3D G3DSA:1.20.1050.10 96 202 5.7E-26 T 29-03-2018 CDC59_RS03690 febdaad2f498911ff2928fc8e4c9c27c 202 Pfam PF13417 Glutathione S-transferase, N-terminal domain 3 75 3.5E-19 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CDC59_RS03690 febdaad2f498911ff2928fc8e4c9c27c 202 Pfam PF13410 Glutathione S-transferase, C-terminal domain 121 189 9.9E-14 T 29-03-2018 CDC59_RS03690 febdaad2f498911ff2928fc8e4c9c27c 202 SUPERFAMILY SSF47616 73 201 2.09E-28 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like CDC59_RS03690 febdaad2f498911ff2928fc8e4c9c27c 202 Gene3D G3DSA:3.40.30.10 1 95 5.0E-23 T 29-03-2018 CDC59_RS19530 8acec283d96273fb4f78daf7ce140654 458 Pfam PF07396 Phosphate-selective porin O and P 106 443 4.2E-8 T 29-03-2018 IPR010870 Phosphate-selective porin O/P CDC59_RS19530 8acec283d96273fb4f78daf7ce140654 458 SUPERFAMILY SSF56935 96 238 3.4E-28 T 29-03-2018 CDC59_RS19530 8acec283d96273fb4f78daf7ce140654 458 SUPERFAMILY SSF56935 271 458 3.4E-28 T 29-03-2018 CDC59_RS19530 8acec283d96273fb4f78daf7ce140654 458 Gene3D G3DSA:2.40.160.10 63 458 1.1E-45 T 29-03-2018 CDC59_RS11415 91663ae6b7a6ab396156b89c4e655ec2 397 Gene3D G3DSA:3.40.50.1100 70 200 1.7E-38 T 29-03-2018 CDC59_RS11415 91663ae6b7a6ab396156b89c4e655ec2 397 Gene3D G3DSA:3.40.50.1100 11 69 4.9E-7 T 29-03-2018 CDC59_RS11415 91663ae6b7a6ab396156b89c4e655ec2 397 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 56 380 4.8E-48 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CDC59_RS11415 91663ae6b7a6ab396156b89c4e655ec2 397 PIRSF PIRSF001413 2 397 2.2E-166 T 29-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CDC59_RS11415 91663ae6b7a6ab396156b89c4e655ec2 397 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 9 391 8.0E-196 T 29-03-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CDC59_RS11415 91663ae6b7a6ab396156b89c4e655ec2 397 SUPERFAMILY SSF53686 5 391 3.27E-151 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CDC59_RS11415 91663ae6b7a6ab396156b89c4e655ec2 397 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 83 97 - T 29-03-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CDC59_RS11415 91663ae6b7a6ab396156b89c4e655ec2 397 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 4 393 53.34 T 29-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CDC59_RS11415 91663ae6b7a6ab396156b89c4e655ec2 397 Gene3D G3DSA:3.40.50.1100 201 395 1.5E-41 T 29-03-2018 CDC59_RS00955 df645c8f0bab5017c81798f582c6b9d0 682 TIGRFAM TIGR00728 OPT_sfam: oligopeptide transporter, OPT superfamily 13 634 1.4E-105 T 29-03-2018 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 CDC59_RS00955 df645c8f0bab5017c81798f582c6b9d0 682 Pfam PF03169 OPT oligopeptide transporter protein 16 634 1.5E-102 T 29-03-2018 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 CDC59_RS00955 df645c8f0bab5017c81798f582c6b9d0 682 TIGRFAM TIGR00733 TIGR00733: oligopeptide transporter, OPT family 16 636 2.3E-210 T 29-03-2018 IPR004814 Oligopeptide transporter OPT CDC59_RS21080 787da573151d83492bdad5b909bfb83a 393 Pfam PF01546 Peptidase family M20/M25/M40 76 387 8.2E-28 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CDC59_RS21080 787da573151d83492bdad5b909bfb83a 393 PIRSF PIRSF005962 2 392 5.4E-116 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CDC59_RS21080 787da573151d83492bdad5b909bfb83a 393 SUPERFAMILY SSF55031 185 298 6.02E-31 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CDC59_RS21080 787da573151d83492bdad5b909bfb83a 393 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 17 378 5.9E-101 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CDC59_RS21080 787da573151d83492bdad5b909bfb83a 393 Pfam PF07687 Peptidase dimerisation domain 188 282 4.7E-12 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CDC59_RS21080 787da573151d83492bdad5b909bfb83a 393 Gene3D G3DSA:3.40.630.10 248 393 8.1E-20 T 29-03-2018 CDC59_RS21080 787da573151d83492bdad5b909bfb83a 393 Gene3D G3DSA:3.40.630.10 3 247 1.5E-47 T 29-03-2018 CDC59_RS21080 787da573151d83492bdad5b909bfb83a 393 SUPERFAMILY SSF53187 5 199 1.36E-80 T 29-03-2018 CDC59_RS21080 787da573151d83492bdad5b909bfb83a 393 SUPERFAMILY SSF53187 300 390 1.36E-80 T 29-03-2018 CDC59_RS04685 332967fc11ae4cf0b35fab63b78b6e27 161 Pfam PF07963 Prokaryotic N-terminal methylation motif 11 35 6.9E-10 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS04685 332967fc11ae4cf0b35fab63b78b6e27 161 SUPERFAMILY SSF54523 15 142 1.88E-19 T 29-03-2018 CDC59_RS04685 332967fc11ae4cf0b35fab63b78b6e27 161 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 12 35 4.9E-10 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS04685 332967fc11ae4cf0b35fab63b78b6e27 161 Gene3D G3DSA:3.30.700.10 15 160 1.7E-18 T 29-03-2018 CDC59_RS04685 332967fc11ae4cf0b35fab63b78b6e27 161 Pfam PF16732 Type IV minor pilin ComP, DNA uptake sequence receptor 36 134 2.9E-14 T 29-03-2018 IPR031982 Type IV minor pilin ComP CDC59_RS03555 9fc4a4b0c2697542a254eb30869a7dc3 347 Pfam PF03466 LysR substrate binding domain 93 303 4.1E-20 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS03555 9fc4a4b0c2697542a254eb30869a7dc3 347 SUPERFAMILY SSF53850 89 304 4.89E-33 T 29-03-2018 CDC59_RS03555 9fc4a4b0c2697542a254eb30869a7dc3 347 Gene3D G3DSA:3.40.190.10 185 276 4.9E-12 T 29-03-2018 CDC59_RS03555 9fc4a4b0c2697542a254eb30869a7dc3 347 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 64 8.8E-13 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS03555 9fc4a4b0c2697542a254eb30869a7dc3 347 SUPERFAMILY SSF46785 2 81 5.44E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS03555 9fc4a4b0c2697542a254eb30869a7dc3 347 Gene3D G3DSA:1.10.10.10 2 84 3.8E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS03555 9fc4a4b0c2697542a254eb30869a7dc3 347 Gene3D G3DSA:3.40.190.10 93 184 2.8E-12 T 29-03-2018 CDC59_RS05755 7e34a9dcfcf37a3ae3eab0c52a93a710 390 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 20 83 1.5E-5 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CDC59_RS05755 7e34a9dcfcf37a3ae3eab0c52a93a710 390 Gene3D G3DSA:2.40.110.10 112 191 1.8E-17 T 29-03-2018 CDC59_RS05755 7e34a9dcfcf37a3ae3eab0c52a93a710 390 SUPERFAMILY SSF56645 12 200 1.96E-33 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CDC59_RS05755 7e34a9dcfcf37a3ae3eab0c52a93a710 390 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 232 359 5.4E-26 T 29-03-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain CDC59_RS05755 7e34a9dcfcf37a3ae3eab0c52a93a710 390 SUPERFAMILY SSF47203 231 371 1.1E-7 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CDC59_RS05755 7e34a9dcfcf37a3ae3eab0c52a93a710 390 Gene3D G3DSA:1.20.140.10 192 378 8.9E-11 T 29-03-2018 CDC59_RS05755 7e34a9dcfcf37a3ae3eab0c52a93a710 390 PIRSF PIRSF016578 1 380 3.6E-108 T 29-03-2018 CDC59_RS05755 7e34a9dcfcf37a3ae3eab0c52a93a710 390 Gene3D G3DSA:1.10.540.10 7 106 6.2E-9 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CDC59_RS23895 84dde089a1fb0f2ae1abb0c4e365f009 531 SUPERFAMILY SSF50447 263 395 9.06E-29 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CDC59_RS23895 84dde089a1fb0f2ae1abb0c4e365f009 531 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 2 529 1.0E-238 T 29-03-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 CDC59_RS23895 84dde089a1fb0f2ae1abb0c4e365f009 531 Pfam PF16658 Class II release factor RF3, C-terminal domain 389 515 8.5E-45 T 29-03-2018 IPR032090 Peptide chain release factor 3, C-terminal CDC59_RS23895 84dde089a1fb0f2ae1abb0c4e365f009 531 Gene3D G3DSA:3.30.70.870 390 466 7.5E-12 T 29-03-2018 CDC59_RS23895 84dde089a1fb0f2ae1abb0c4e365f009 531 Gene3D G3DSA:3.40.50.300 6 278 7.6E-35 T 29-03-2018 CDC59_RS23895 84dde089a1fb0f2ae1abb0c4e365f009 531 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 2 528 52.517 T 29-03-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 CDC59_RS23895 84dde089a1fb0f2ae1abb0c4e365f009 531 Pfam PF00009 Elongation factor Tu GTP binding domain 10 278 1.7E-49 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDC59_RS23895 84dde089a1fb0f2ae1abb0c4e365f009 531 SUPERFAMILY SSF54980 395 467 2.27E-16 T 29-03-2018 IPR035647 EF-G domain III/V-like CDC59_RS23895 84dde089a1fb0f2ae1abb0c4e365f009 531 SUPERFAMILY SSF52540 7 279 9.65E-85 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS23895 84dde089a1fb0f2ae1abb0c4e365f009 531 Pfam PF03144 Elongation factor Tu domain 2 316 380 6.8E-8 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CDC59_RS23895 84dde089a1fb0f2ae1abb0c4e365f009 531 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 56 71 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site CDC59_RS23895 84dde089a1fb0f2ae1abb0c4e365f009 531 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 15 150 1.5E-19 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CDC59_RS23895 84dde089a1fb0f2ae1abb0c4e365f009 531 Gene3D G3DSA:2.40.30.10 279 389 5.1E-22 T 29-03-2018 CDC59_RS23895 84dde089a1fb0f2ae1abb0c4e365f009 531 PRINTS PR00315 GTP-binding elongation factor signature 103 114 1.1E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDC59_RS23895 84dde089a1fb0f2ae1abb0c4e365f009 531 PRINTS PR00315 GTP-binding elongation factor signature 139 148 1.1E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDC59_RS23895 84dde089a1fb0f2ae1abb0c4e365f009 531 PRINTS PR00315 GTP-binding elongation factor signature 87 97 1.1E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDC59_RS23895 84dde089a1fb0f2ae1abb0c4e365f009 531 PRINTS PR00315 GTP-binding elongation factor signature 63 71 1.1E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDC59_RS23895 84dde089a1fb0f2ae1abb0c4e365f009 531 PRINTS PR00315 GTP-binding elongation factor signature 13 26 1.1E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDC59_RS14235 646fea98811b6c1bf97e1fb464aa8776 499 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 478 485 - T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CDC59_RS14235 646fea98811b6c1bf97e1fb464aa8776 499 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 4 48 2.0E-16 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CDC59_RS14235 646fea98811b6c1bf97e1fb464aa8776 499 Pfam PF04552 Sigma-54, DNA binding domain 341 497 1.0E-67 T 29-03-2018 IPR007634 RNA polymerase sigma factor 54, DNA-binding CDC59_RS14235 646fea98811b6c1bf97e1fb464aa8776 499 PIRSF PIRSF000774 1 499 6.1E-156 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CDC59_RS14235 646fea98811b6c1bf97e1fb464aa8776 499 PRINTS PR00045 Sigma-54 factor signature 415 426 2.4E-29 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CDC59_RS14235 646fea98811b6c1bf97e1fb464aa8776 499 PRINTS PR00045 Sigma-54 factor signature 211 228 2.4E-29 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CDC59_RS14235 646fea98811b6c1bf97e1fb464aa8776 499 PRINTS PR00045 Sigma-54 factor signature 399 411 2.4E-29 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CDC59_RS14235 646fea98811b6c1bf97e1fb464aa8776 499 PRINTS PR00045 Sigma-54 factor signature 473 491 2.4E-29 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CDC59_RS14235 646fea98811b6c1bf97e1fb464aa8776 499 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 9 497 9.3E-143 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CDC59_RS14235 646fea98811b6c1bf97e1fb464aa8776 499 Gene3D G3DSA:1.10.10.10 459 499 0.49 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS14235 646fea98811b6c1bf97e1fb464aa8776 499 Pfam PF04963 Sigma-54 factor, core binding domain 136 326 9.4E-57 T 29-03-2018 IPR007046 RNA polymerase sigma factor 54, core-binding GO:0003677|GO:0006352 CDC59_RS14235 646fea98811b6c1bf97e1fb464aa8776 499 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 387 406 - T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CDC59_RS14235 646fea98811b6c1bf97e1fb464aa8776 499 Gene3D G3DSA:1.10.10.10 345 437 7.4E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS18850 ae4a0a0c39d313371526ec2abb702d7d 739 SUPERFAMILY SSF63737 88 292 1.57E-36 T 29-03-2018 CDC59_RS18850 ae4a0a0c39d313371526ec2abb702d7d 739 Gene3D G3DSA:1.10.390.10 392 557 3.2E-36 T 29-03-2018 CDC59_RS18850 ae4a0a0c39d313371526ec2abb702d7d 739 Gene3D G3DSA:2.60.40.1730 76 294 6.6E-38 T 29-03-2018 CDC59_RS18850 ae4a0a0c39d313371526ec2abb702d7d 739 SUPERFAMILY SSF55486 307 565 1.9E-58 T 29-03-2018 CDC59_RS18850 ae4a0a0c39d313371526ec2abb702d7d 739 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 405 420 3.3E-16 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CDC59_RS18850 ae4a0a0c39d313371526ec2abb702d7d 739 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 228 243 3.3E-16 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CDC59_RS18850 ae4a0a0c39d313371526ec2abb702d7d 739 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 276 291 3.3E-16 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CDC59_RS18850 ae4a0a0c39d313371526ec2abb702d7d 739 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 424 436 3.3E-16 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CDC59_RS18850 ae4a0a0c39d313371526ec2abb702d7d 739 Pfam PF01433 Peptidase family M1 domain 310 552 3.5E-52 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CDC59_RS14050 73eca382535ffb0480dfb073364393e9 169 SUPERFAMILY SSF52540 1 160 8.77E-27 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS14050 73eca382535ffb0480dfb073364393e9 169 Gene3D G3DSA:3.40.50.300 1 168 3.0E-31 T 29-03-2018 CDC59_RS14050 73eca382535ffb0480dfb073364393e9 169 TIGRFAM TIGR01313 therm_gnt_kin: carbohydrate kinase, thermoresistant glucokinase family 3 158 8.2E-53 T 29-03-2018 IPR006001 Carbohydrate kinase, thermoresistant glucokinase GO:0005975|GO:0016301 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 CDC59_RS14050 73eca382535ffb0480dfb073364393e9 169 Pfam PF01202 Shikimate kinase 9 160 1.1E-21 T 29-03-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CDC59_RS17590 b51bb9af0abc8bf5b06c2b0d4af28a3b 1188 Pfam PF00668 Condensation domain 39 471 1.1E-74 T 29-03-2018 IPR001242 Condensation domain CDC59_RS17590 b51bb9af0abc8bf5b06c2b0d4af28a3b 1188 Gene3D G3DSA:3.40.50.1000 670 830 8.6E-12 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS17590 b51bb9af0abc8bf5b06c2b0d4af28a3b 1188 TIGRFAM TIGR01681 HAD-SF-IIIC: HAD phosphatase, family IIIC 672 789 3.4E-17 T 29-03-2018 IPR010033 HAD-superfamily phosphatase, subfamily IIIC CDC59_RS17590 b51bb9af0abc8bf5b06c2b0d4af28a3b 1188 Pfam PF00550 Phosphopantetheine attachment site 1088 1151 4.2E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS17590 b51bb9af0abc8bf5b06c2b0d4af28a3b 1188 TIGRFAM TIGR01686 FkbH: FkbH domain 671 995 1.0E-92 T 29-03-2018 IPR010037 FkbH domain CDC59_RS17590 b51bb9af0abc8bf5b06c2b0d4af28a3b 1188 SUPERFAMILY SSF52777 229 471 2.11E-44 T 29-03-2018 CDC59_RS17590 b51bb9af0abc8bf5b06c2b0d4af28a3b 1188 SUPERFAMILY SSF56784 671 787 1.21E-9 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS17590 b51bb9af0abc8bf5b06c2b0d4af28a3b 1188 SMART SM00823 Phosphopantetheine attachment site 1086 1155 2.8E-4 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CDC59_RS17590 b51bb9af0abc8bf5b06c2b0d4af28a3b 1188 SUPERFAMILY SSF52777 44 221 1.89E-40 T 29-03-2018 CDC59_RS17590 b51bb9af0abc8bf5b06c2b0d4af28a3b 1188 SUPERFAMILY SSF47336 1080 1151 2.09E-18 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS17590 b51bb9af0abc8bf5b06c2b0d4af28a3b 1188 Gene3D G3DSA:1.10.1200.10 1080 1158 2.2E-20 T 29-03-2018 CDC59_RS17590 b51bb9af0abc8bf5b06c2b0d4af28a3b 1188 Gene3D G3DSA:3.40.630.30 857 1000 5.3E-5 T 29-03-2018 CDC59_RS17590 b51bb9af0abc8bf5b06c2b0d4af28a3b 1188 Gene3D G3DSA:3.30.559.10 6 229 1.7E-33 T 29-03-2018 CDC59_RS16360 5dda3461e05196c47c28b13034e55a6b 398 Gene3D G3DSA:3.10.310.10 3 193 9.2E-86 T 29-03-2018 CDC59_RS16360 5dda3461e05196c47c28b13034e55a6b 398 SUPERFAMILY SSF54506 191 396 3.61E-75 T 29-03-2018 CDC59_RS16360 5dda3461e05196c47c28b13034e55a6b 398 Gene3D G3DSA:3.10.310.10 194 378 2.4E-72 T 29-03-2018 CDC59_RS16360 5dda3461e05196c47c28b13034e55a6b 398 SUPERFAMILY SSF54506 3 182 7.46E-73 T 29-03-2018 CDC59_RS16360 5dda3461e05196c47c28b13034e55a6b 398 TIGRFAM TIGR02334 prpF: probable AcnD-accessory protein PrpF 5 397 1.4E-229 T 29-03-2018 IPR012709 2-methyl-aconitate isomerase PrpF GO:0016853|GO:0019629 CDC59_RS16360 5dda3461e05196c47c28b13034e55a6b 398 Pfam PF04303 PrpF protein 6 396 2.3E-178 T 29-03-2018 IPR007400 PrpF protein CDC59_RS02440 d5bffb3ca91795c8e6917d20785610e7 76 Pfam PF13627 Prokaryotic lipoprotein-attachment site 10 32 9.2E-8 T 29-03-2018 IPR032831 Prokaryotic lipoprotein-attachment site CDC59_RS21535 d64ad23662b541e30e0348c4319313d9 102 SMART SM00528 56 101 1.7E-12 T 29-03-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 CDC59_RS21535 d64ad23662b541e30e0348c4319313d9 102 Pfam PF00816 H-NS histone family 7 95 7.5E-25 T 29-03-2018 IPR001801 Histone-like protein H-NS GO:0003677|GO:0005622|GO:0006355 CDC59_RS21535 d64ad23662b541e30e0348c4319313d9 102 Gene3D G3DSA:4.10.430.10 64 101 1.2E-15 T 29-03-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 CDC59_RS21535 d64ad23662b541e30e0348c4319313d9 102 SUPERFAMILY SSF81273 62 101 1.02E-10 T 29-03-2018 CDC59_RS14535 c7d1f7c69bde121e468fa093d7eba7bc 586 Gene3D G3DSA:3.20.20.60 264 586 8.6E-92 T 29-03-2018 CDC59_RS14535 c7d1f7c69bde121e468fa093d7eba7bc 586 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 193 204 - T 29-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 CDC59_RS14535 c7d1f7c69bde121e468fa093d7eba7bc 586 Pfam PF05524 PEP-utilising enzyme, N-terminal 6 129 2.0E-28 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CDC59_RS14535 c7d1f7c69bde121e468fa093d7eba7bc 586 Gene3D G3DSA:3.50.30.10 143 263 2.8E-29 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CDC59_RS14535 c7d1f7c69bde121e468fa093d7eba7bc 586 Gene3D G3DSA:1.10.274.10 27 142 3.5E-30 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CDC59_RS14535 c7d1f7c69bde121e468fa093d7eba7bc 586 SUPERFAMILY SSF52009 128 253 8.37E-32 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CDC59_RS14535 c7d1f7c69bde121e468fa093d7eba7bc 586 SUPERFAMILY SSF51621 258 558 1.6E-98 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CDC59_RS14535 c7d1f7c69bde121e468fa093d7eba7bc 586 SUPERFAMILY SSF47831 28 146 4.45E-29 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CDC59_RS14535 c7d1f7c69bde121e468fa093d7eba7bc 586 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 462 480 - T 29-03-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 CDC59_RS14535 c7d1f7c69bde121e468fa093d7eba7bc 586 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 515 527 6.4E-24 T 29-03-2018 CDC59_RS14535 c7d1f7c69bde121e468fa093d7eba7bc 586 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 462 477 6.4E-24 T 29-03-2018 CDC59_RS14535 c7d1f7c69bde121e468fa093d7eba7bc 586 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 479 494 6.4E-24 T 29-03-2018 CDC59_RS14535 c7d1f7c69bde121e468fa093d7eba7bc 586 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 302 321 6.4E-24 T 29-03-2018 CDC59_RS14535 c7d1f7c69bde121e468fa093d7eba7bc 586 PIRSF PIRSF000732 1 586 7.2E-207 T 29-03-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 CDC59_RS14535 c7d1f7c69bde121e468fa093d7eba7bc 586 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 260 555 1.3E-107 T 29-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 CDC59_RS14535 c7d1f7c69bde121e468fa093d7eba7bc 586 Pfam PF00391 PEP-utilising enzyme, mobile domain 162 234 9.9E-23 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CDC59_RS14535 c7d1f7c69bde121e468fa093d7eba7bc 586 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 5 572 1.6E-158 T 29-03-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 CDC59_RS08665 faf1e50bfffaa09c8a62c5b1387776af 122 Pfam PF01250 Ribosomal protein S6 3 90 2.4E-27 T 29-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS08665 faf1e50bfffaa09c8a62c5b1387776af 122 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 93 6.6E-33 T 29-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS08665 faf1e50bfffaa09c8a62c5b1387776af 122 SUPERFAMILY SSF54995 1 104 1.1E-36 T 29-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS08665 faf1e50bfffaa09c8a62c5b1387776af 122 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 94 21.713 T 29-03-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 CDC59_RS08665 faf1e50bfffaa09c8a62c5b1387776af 122 Gene3D G3DSA:3.30.70.60 1 100 1.9E-30 T 29-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 CDC59_RS07355 837ea6b8218eff840615aa404c79043b 598 Gene3D G3DSA:3.30.70.240 391 550 4.7E-28 T 29-03-2018 CDC59_RS07355 837ea6b8218eff840615aa404c79043b 598 Pfam PF00679 Elongation factor G C-terminus 400 485 2.0E-23 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like CDC59_RS07355 837ea6b8218eff840615aa404c79043b 598 SUPERFAMILY SSF54980 293 371 3.02E-18 T 29-03-2018 IPR035647 EF-G domain III/V-like CDC59_RS07355 837ea6b8218eff840615aa404c79043b 598 SUPERFAMILY SSF54980 400 494 2.06E-26 T 29-03-2018 IPR035647 EF-G domain III/V-like CDC59_RS07355 837ea6b8218eff840615aa404c79043b 598 Gene3D G3DSA:3.30.70.870 289 368 2.3E-28 T 29-03-2018 CDC59_RS07355 837ea6b8218eff840615aa404c79043b 598 Pfam PF00009 Elongation factor Tu GTP binding domain 3 181 5.0E-52 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDC59_RS07355 837ea6b8218eff840615aa404c79043b 598 SMART SM00838 399 486 7.4E-4 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like CDC59_RS07355 837ea6b8218eff840615aa404c79043b 598 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 5 169 1.2E-16 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CDC59_RS07355 837ea6b8218eff840615aa404c79043b 598 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 42 57 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site CDC59_RS07355 837ea6b8218eff840615aa404c79043b 598 TIGRFAM TIGR01393 lepA: elongation factor 4 3 596 1.5E-298 T 29-03-2018 IPR006297 Elongation factor 4 GO:0005525 CDC59_RS07355 837ea6b8218eff840615aa404c79043b 598 Pfam PF03144 Elongation factor Tu domain 2 205 275 2.5E-10 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CDC59_RS07355 837ea6b8218eff840615aa404c79043b 598 SUPERFAMILY SSF52540 2 230 2.36E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS07355 837ea6b8218eff840615aa404c79043b 598 Pfam PF06421 GTP-binding protein LepA C-terminus 488 594 1.8E-49 T 29-03-2018 IPR013842 GTP-binding protein LepA, C-terminal CDC59_RS07355 837ea6b8218eff840615aa404c79043b 598 Gene3D G3DSA:2.40.30.10 191 288 1.7E-23 T 29-03-2018 CDC59_RS07355 837ea6b8218eff840615aa404c79043b 598 PRINTS PR00315 GTP-binding elongation factor signature 90 101 2.3E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDC59_RS07355 837ea6b8218eff840615aa404c79043b 598 PRINTS PR00315 GTP-binding elongation factor signature 126 135 2.3E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDC59_RS07355 837ea6b8218eff840615aa404c79043b 598 PRINTS PR00315 GTP-binding elongation factor signature 6 19 2.3E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDC59_RS07355 837ea6b8218eff840615aa404c79043b 598 PRINTS PR00315 GTP-binding elongation factor signature 74 84 2.3E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDC59_RS07355 837ea6b8218eff840615aa404c79043b 598 PRINTS PR00315 GTP-binding elongation factor signature 49 57 2.3E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CDC59_RS07355 837ea6b8218eff840615aa404c79043b 598 Hamap MF_00071 Elongation factor 4 [lepA]. 1 598 306.23 T 29-03-2018 IPR006297 Elongation factor 4 GO:0005525 CDC59_RS07355 837ea6b8218eff840615aa404c79043b 598 Gene3D G3DSA:3.40.50.300 1 190 4.3E-35 T 29-03-2018 CDC59_RS01625 46f129bc7a60aeb1cd2f0901d1780aba 637 Gene3D G3DSA:1.10.8.60 508 572 6.1E-17 T 29-03-2018 CDC59_RS01625 46f129bc7a60aeb1cd2f0901d1780aba 637 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 544 553 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site CDC59_RS01625 46f129bc7a60aeb1cd2f0901d1780aba 637 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 613 633 1.2E-9 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CDC59_RS01625 46f129bc7a60aeb1cd2f0901d1780aba 637 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 596 613 1.2E-9 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CDC59_RS01625 46f129bc7a60aeb1cd2f0901d1780aba 637 SUPERFAMILY SSF52540 347 574 3.99E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS01625 46f129bc7a60aeb1cd2f0901d1780aba 637 Gene3D G3DSA:1.10.10.60 573 635 2.8E-19 T 29-03-2018 CDC59_RS01625 46f129bc7a60aeb1cd2f0901d1780aba 637 Gene3D G3DSA:3.30.450.20 235 320 8.4E-6 T 29-03-2018 CDC59_RS01625 46f129bc7a60aeb1cd2f0901d1780aba 637 Gene3D G3DSA:3.30.450.40 5 218 1.4E-10 T 29-03-2018 IPR029016 GAF domain-like CDC59_RS01625 46f129bc7a60aeb1cd2f0901d1780aba 637 SMART SM00382 355 498 1.8E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS01625 46f129bc7a60aeb1cd2f0901d1780aba 637 Pfam PF02954 Bacterial regulatory protein, Fis family 590 630 3.8E-14 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CDC59_RS01625 46f129bc7a60aeb1cd2f0901d1780aba 637 SUPERFAMILY SSF46689 544 632 2.82E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS01625 46f129bc7a60aeb1cd2f0901d1780aba 637 Pfam PF01590 GAF domain 77 202 5.3E-7 T 29-03-2018 IPR003018 GAF domain GO:0005515 CDC59_RS01625 46f129bc7a60aeb1cd2f0901d1780aba 637 SUPERFAMILY SSF55785 239 300 8.1E-7 T 29-03-2018 IPR000014 PAS domain CDC59_RS01625 46f129bc7a60aeb1cd2f0901d1780aba 637 SUPERFAMILY SSF55781 72 197 6.47E-9 T 29-03-2018 IPR029016 GAF domain-like CDC59_RS01625 46f129bc7a60aeb1cd2f0901d1780aba 637 Pfam PF00158 Sigma-54 interaction domain 339 501 2.4E-62 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CDC59_RS01625 46f129bc7a60aeb1cd2f0901d1780aba 637 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 422 437 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CDC59_RS01625 46f129bc7a60aeb1cd2f0901d1780aba 637 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 359 372 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CDC59_RS01625 46f129bc7a60aeb1cd2f0901d1780aba 637 Gene3D G3DSA:3.40.50.300 321 507 6.1E-23 T 29-03-2018 CDC59_RS17720 1b77fc98e47a61a3a52876dd421b233f 622 Pfam PF02954 Bacterial regulatory protein, Fis family 575 614 2.9E-12 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CDC59_RS17720 1b77fc98e47a61a3a52876dd421b233f 622 SUPERFAMILY SSF111126 51 206 4.71E-9 T 29-03-2018 IPR024096 NO signalling/Golgi transport ligand-binding domain CDC59_RS17720 1b77fc98e47a61a3a52876dd421b233f 622 Pfam PF00158 Sigma-54 interaction domain 272 439 1.6E-67 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CDC59_RS17720 1b77fc98e47a61a3a52876dd421b233f 622 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 358 373 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CDC59_RS17720 1b77fc98e47a61a3a52876dd421b233f 622 SUPERFAMILY SSF52540 272 513 2.13E-71 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS17720 1b77fc98e47a61a3a52876dd421b233f 622 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 485 494 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site CDC59_RS17720 1b77fc98e47a61a3a52876dd421b233f 622 Gene3D G3DSA:1.10.10.60 580 614 1.6E-9 T 29-03-2018 CDC59_RS17720 1b77fc98e47a61a3a52876dd421b233f 622 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 296 309 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CDC59_RS17720 1b77fc98e47a61a3a52876dd421b233f 622 Gene3D G3DSA:3.30.1380.20 51 217 3.4E-34 T 29-03-2018 CDC59_RS17720 1b77fc98e47a61a3a52876dd421b233f 622 SMART SM00382 292 436 2.0E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS17720 1b77fc98e47a61a3a52876dd421b233f 622 Pfam PF02830 V4R domain 150 210 4.9E-17 T 29-03-2018 IPR004096 4-vinyl reductase, 4VR CDC59_RS17720 1b77fc98e47a61a3a52876dd421b233f 622 Pfam PF06505 Activator of aromatic catabolism 38 136 2.0E-36 T 29-03-2018 IPR010523 Activator of aromatic catabolism CDC59_RS17720 1b77fc98e47a61a3a52876dd421b233f 622 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 581 598 6.4E-10 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CDC59_RS17720 1b77fc98e47a61a3a52876dd421b233f 622 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 598 618 6.4E-10 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CDC59_RS17720 1b77fc98e47a61a3a52876dd421b233f 622 Gene3D G3DSA:1.10.8.60 445 579 3.2E-23 T 29-03-2018 CDC59_RS17720 1b77fc98e47a61a3a52876dd421b233f 622 SUPERFAMILY SSF46689 486 522 2.2E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS17720 1b77fc98e47a61a3a52876dd421b233f 622 SUPERFAMILY SSF46689 565 614 2.2E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS17720 1b77fc98e47a61a3a52876dd421b233f 622 SMART SM00989 149 211 1.5E-22 T 29-03-2018 IPR004096 4-vinyl reductase, 4VR CDC59_RS17720 1b77fc98e47a61a3a52876dd421b233f 622 Gene3D G3DSA:3.40.50.300 268 444 9.6E-27 T 29-03-2018 CDC59_RS17720 1b77fc98e47a61a3a52876dd421b233f 622 ProDom PD485437 REGULATOR TRANSCRIPTIONAL FIS-TYPE HELIX-TURN-HELIX ACTIVATOR PLASMID FAMILY PHENOL-DEGRADATIVE FIS SIGMA-54 57 164 1.0E-55 T 29-03-2018 IPR010523 Activator of aromatic catabolism CDC59_RS15665 7b4f3a2be4213f9f75e2915e124692d2 276 Pfam PF02219 Methylenetetrahydrofolate reductase 4 275 7.3E-90 T 29-03-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CDC59_RS15665 7b4f3a2be4213f9f75e2915e124692d2 276 Gene3D G3DSA:3.20.20.220 2 276 1.1E-99 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like CDC59_RS15665 7b4f3a2be4213f9f75e2915e124692d2 276 SUPERFAMILY SSF51730 4 275 2.94E-99 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like CDC59_RS15665 7b4f3a2be4213f9f75e2915e124692d2 276 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 6 274 1.5E-103 T 29-03-2018 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841 CDC59_RS17945 9d198c4b1eb3867fffedbe0efa67f375 343 SMART SM00829 16 338 7.1E-6 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CDC59_RS17945 9d198c4b1eb3867fffedbe0efa67f375 343 SUPERFAMILY SSF50129 5 175 1.11E-45 T 29-03-2018 IPR011032 GroES-like CDC59_RS17945 9d198c4b1eb3867fffedbe0efa67f375 343 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 31 138 7.4E-28 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CDC59_RS17945 9d198c4b1eb3867fffedbe0efa67f375 343 SUPERFAMILY SSF51735 143 302 7.16E-33 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS17945 9d198c4b1eb3867fffedbe0efa67f375 343 Gene3D G3DSA:3.90.180.10 3 172 1.4E-47 T 29-03-2018 CDC59_RS17945 9d198c4b1eb3867fffedbe0efa67f375 343 Gene3D G3DSA:3.90.180.10 304 341 0.0088 T 29-03-2018 CDC59_RS17945 9d198c4b1eb3867fffedbe0efa67f375 343 Pfam PF00107 Zinc-binding dehydrogenase 180 302 2.9E-19 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CDC59_RS17945 9d198c4b1eb3867fffedbe0efa67f375 343 Gene3D G3DSA:3.40.50.720 173 288 2.0E-19 T 29-03-2018 CDC59_RS07415 bde569789d5773b9e0711f3f77395e08 191 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 54 76 - T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CDC59_RS07415 bde569789d5773b9e0711f3f77395e08 191 Pfam PF01066 CDP-alcohol phosphatidyltransferase 5 76 6.1E-16 T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CDC59_RS07415 bde569789d5773b9e0711f3f77395e08 191 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 4 186 7.2E-51 T 29-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 CDC59_RS07415 bde569789d5773b9e0711f3f77395e08 191 PIRSF PIRSF000847 1 191 2.9E-42 T 29-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 CDC59_RS20015 1d82f5fd9140af14be8b6ecbbea51915 450 SUPERFAMILY SSF103473 15 448 2.75E-82 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS20015 1d82f5fd9140af14be8b6ecbbea51915 450 Pfam PF07690 Major Facilitator Superfamily 30 320 4.2E-51 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDC59_RS20015 1d82f5fd9140af14be8b6ecbbea51915 450 PIRSF PIRSF002808 2 449 6.2E-55 T 29-03-2018 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 CDC59_RS20015 1d82f5fd9140af14be8b6ecbbea51915 450 Gene3D G3DSA:1.20.1250.20 15 222 1.4E-39 T 29-03-2018 CDC59_RS20015 1d82f5fd9140af14be8b6ecbbea51915 450 Gene3D G3DSA:1.20.1250.20 244 448 8.8E-24 T 29-03-2018 CDC59_RS20015 1d82f5fd9140af14be8b6ecbbea51915 450 TIGRFAM TIGR00893 2A0114: D-galactonate transporter 32 439 2.8E-149 T 29-03-2018 IPR004744 D-galactonate transporter GO:0005215|GO:0006810|GO:0016021 CDC59_RS11670 76f3622de2ad7083a12eaf434097c82e 100 Gene3D G3DSA:3.30.280.10 2 99 6.5E-48 T 29-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CDC59_RS11670 76f3622de2ad7083a12eaf434097c82e 100 Pfam PF00547 Urease, gamma subunit 2 99 9.4E-47 T 29-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CDC59_RS11670 76f3622de2ad7083a12eaf434097c82e 100 PIRSF PIRSF001223 1 100 1.5E-51 T 29-03-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CDC59_RS11670 76f3622de2ad7083a12eaf434097c82e 100 TIGRFAM TIGR00193 urease_gam: urease, gamma subunit 2 99 2.3E-52 T 29-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CDC59_RS11670 76f3622de2ad7083a12eaf434097c82e 100 ProDom PD002319 SUBUNIT GAMMA HYDROLASE UREASE UREA AMIDOHYDROLASE UREASE ALPHA GAMMA/BETA METAL-BINDING 9 99 3.0E-45 T 29-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CDC59_RS11670 76f3622de2ad7083a12eaf434097c82e 100 SUPERFAMILY SSF54111 2 99 3.01E-46 T 29-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CDC59_RS11670 76f3622de2ad7083a12eaf434097c82e 100 Hamap MF_00739 Urease subunit gamma [ureA]. 1 100 34.764 T 29-03-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CDC59_RS08710 1b1169e299bb2cb94881239e372d12a9 573 SMART SM00670 111 246 1.8E-11 T 29-03-2018 IPR002716 PIN domain CDC59_RS08710 1b1169e299bb2cb94881239e372d12a9 573 SUPERFAMILY SSF52540 359 445 4.84E-30 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS08710 1b1169e299bb2cb94881239e372d12a9 573 SUPERFAMILY SSF52540 236 290 4.84E-30 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS08710 1b1169e299bb2cb94881239e372d12a9 573 SUPERFAMILY SSF52540 478 552 4.84E-30 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS08710 1b1169e299bb2cb94881239e372d12a9 573 Gene3D G3DSA:3.40.50.300 358 566 2.3E-19 T 29-03-2018 CDC59_RS08710 1b1169e299bb2cb94881239e372d12a9 573 Pfam PF13638 PIN domain 113 258 3.3E-39 T 29-03-2018 IPR002716 PIN domain CDC59_RS08710 1b1169e299bb2cb94881239e372d12a9 573 Pfam PF02562 PhoH-like protein 360 567 5.6E-54 T 29-03-2018 IPR003714 PhoH-like protein GO:0005524 CDC59_RS08710 1b1169e299bb2cb94881239e372d12a9 573 SUPERFAMILY SSF88723 209 262 5.69E-11 T 29-03-2018 IPR029060 PIN domain-like CDC59_RS08710 1b1169e299bb2cb94881239e372d12a9 573 SUPERFAMILY SSF88723 111 172 5.69E-11 T 29-03-2018 IPR029060 PIN domain-like CDC59_RS08710 1b1169e299bb2cb94881239e372d12a9 573 Gene3D G3DSA:3.40.50.1010 110 357 2.2E-45 T 29-03-2018 IPR029060 PIN domain-like CDC59_RS07855 66867e6b0b1a8baa9166fae53d5382e6 288 SUPERFAMILY SSF75217 14 193 5.95E-30 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases CDC59_RS07855 66867e6b0b1a8baa9166fae53d5382e6 288 PIRSF PIRSF004808 22 276 2.4E-58 T 29-03-2018 IPR004384 RNA methyltransferase TrmH, group 1 GO:0006396|GO:0008173 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CDC59_RS07855 66867e6b0b1a8baa9166fae53d5382e6 288 Pfam PF00588 SpoU rRNA Methylase family 27 184 5.9E-28 T 29-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CDC59_RS07855 66867e6b0b1a8baa9166fae53d5382e6 288 Gene3D G3DSA:3.40.1280.10 11 195 5.4E-37 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CDC59_RS07855 66867e6b0b1a8baa9166fae53d5382e6 288 TIGRFAM TIGR00050 rRNA_methyl_1: RNA methyltransferase, TrmH family, group 1 25 268 1.1E-53 T 29-03-2018 IPR004384 RNA methyltransferase TrmH, group 1 GO:0006396|GO:0008173 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CDC59_RS03940 5fd33d48c40d873cbaad7ddaff01efb8 415 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 75 86 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CDC59_RS03940 5fd33d48c40d873cbaad7ddaff01efb8 415 Pfam PF12838 4Fe-4S dicluster domain 24 89 1.1E-12 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CDC59_RS03940 5fd33d48c40d873cbaad7ddaff01efb8 415 Pfam PF02754 Cysteine-rich domain 311 395 4.0E-11 T 29-03-2018 IPR004017 Cysteine-rich domain CDC59_RS03940 5fd33d48c40d873cbaad7ddaff01efb8 415 Pfam PF02754 Cysteine-rich domain 178 260 7.9E-10 T 29-03-2018 IPR004017 Cysteine-rich domain CDC59_RS03940 5fd33d48c40d873cbaad7ddaff01efb8 415 Gene3D G3DSA:3.30.70.20 34 81 1.8E-9 T 29-03-2018 CDC59_RS03940 5fd33d48c40d873cbaad7ddaff01efb8 415 PIRSF PIRSF000139 8 415 6.5E-110 T 29-03-2018 CDC59_RS03940 5fd33d48c40d873cbaad7ddaff01efb8 415 Gene3D G3DSA:3.30.70.20 7 33 0.016 T 29-03-2018 CDC59_RS03940 5fd33d48c40d873cbaad7ddaff01efb8 415 SUPERFAMILY SSF54862 21 120 1.17E-20 T 29-03-2018 CDC59_RS03940 5fd33d48c40d873cbaad7ddaff01efb8 415 Gene3D G3DSA:3.30.70.20 82 357 3.3E-4 T 29-03-2018 CDC59_RS03940 5fd33d48c40d873cbaad7ddaff01efb8 415 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 25 36 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CDC59_RS19445 3e0401e30b9dcc1e31b466881209dd69 558 Gene3D G3DSA:3.50.50.60 6 184 6.2E-16 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS19445 3e0401e30b9dcc1e31b466881209dd69 558 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 176 191 1.6E-37 T 29-03-2018 CDC59_RS19445 3e0401e30b9dcc1e31b466881209dd69 558 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 28 50 1.6E-37 T 29-03-2018 CDC59_RS19445 3e0401e30b9dcc1e31b466881209dd69 558 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 316 332 1.6E-37 T 29-03-2018 CDC59_RS19445 3e0401e30b9dcc1e31b466881209dd69 558 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 352 368 1.6E-37 T 29-03-2018 CDC59_RS19445 3e0401e30b9dcc1e31b466881209dd69 558 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 334 352 1.6E-37 T 29-03-2018 CDC59_RS19445 3e0401e30b9dcc1e31b466881209dd69 558 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 301 316 1.6E-37 T 29-03-2018 CDC59_RS19445 3e0401e30b9dcc1e31b466881209dd69 558 SUPERFAMILY SSF51905 29 197 8.03E-67 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS19445 3e0401e30b9dcc1e31b466881209dd69 558 SUPERFAMILY SSF51905 288 400 8.03E-67 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS19445 3e0401e30b9dcc1e31b466881209dd69 558 Gene3D G3DSA:3.30.9.10 185 309 1.2E-26 T 29-03-2018 CDC59_RS19445 3e0401e30b9dcc1e31b466881209dd69 558 Gene3D G3DSA:3.30.9.10 310 404 1.5E-17 T 29-03-2018 CDC59_RS19445 3e0401e30b9dcc1e31b466881209dd69 558 Pfam PF01494 FAD binding domain 29 365 2.3E-69 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 CDC59_RS14110 9bee4ee3cf161206e82faba3a2679c7c 833 SUPERFAMILY SSF82866 673 809 9.29E-18 T 29-03-2018 CDC59_RS14110 9bee4ee3cf161206e82faba3a2679c7c 833 Pfam PF03176 MMPL family 184 439 1.4E-17 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CDC59_RS14110 9bee4ee3cf161206e82faba3a2679c7c 833 Pfam PF03176 MMPL family 671 809 1.5E-4 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CDC59_RS14110 9bee4ee3cf161206e82faba3a2679c7c 833 Gene3D G3DSA:1.20.1640.10 626 812 4.0E-20 T 29-03-2018 CDC59_RS14110 9bee4ee3cf161206e82faba3a2679c7c 833 SUPERFAMILY SSF82866 191 407 2.35E-21 T 29-03-2018 CDC59_RS14110 9bee4ee3cf161206e82faba3a2679c7c 833 Gene3D G3DSA:1.20.1640.10 198 409 2.9E-21 T 29-03-2018 CDC59_RS12140 da37c073864dbd57efd7445b1ae60d26 397 Gene3D G3DSA:1.25.40.10 68 223 1.4E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS12140 da37c073864dbd57efd7445b1ae60d26 397 SUPERFAMILY SSF48452 250 391 5.38E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS12140 da37c073864dbd57efd7445b1ae60d26 397 Pfam PF07219 HemY protein N-terminus 27 131 5.1E-23 T 29-03-2018 IPR010817 HemY, N-terminal CDC59_RS12140 da37c073864dbd57efd7445b1ae60d26 397 Gene3D G3DSA:1.25.40.10 224 397 3.6E-15 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS12140 da37c073864dbd57efd7445b1ae60d26 397 TIGRFAM TIGR00540 TPR_hemY_coli: heme biosynthesis-associated TPR protein 2 391 6.1E-132 T 29-03-2018 IPR005254 Heme biosynthesis-associated TPR protein GO:0016020|GO:0042168 CDC59_RS00695 9c24cb04cd5c93183ee3c736901eac2c 286 SUPERFAMILY SSF53474 17 285 3.99E-41 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS00695 9c24cb04cd5c93183ee3c736901eac2c 286 Pfam PF12146 Serine aminopeptidase, S33 36 268 2.2E-70 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 CDC59_RS00695 9c24cb04cd5c93183ee3c736901eac2c 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 223 237 6.7E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS00695 9c24cb04cd5c93183ee3c736901eac2c 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 65 80 6.7E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS00695 9c24cb04cd5c93183ee3c736901eac2c 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 113 126 6.7E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS00695 9c24cb04cd5c93183ee3c736901eac2c 286 Gene3D G3DSA:3.40.50.1820 1 286 9.9E-48 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS01930 ca9025cf296beba068fbaf4f2efa7fb8 238 Gene3D G3DSA:3.40.30.10 1 99 6.8E-14 T 29-03-2018 CDC59_RS01930 ca9025cf296beba068fbaf4f2efa7fb8 238 SUPERFAMILY SSF47616 107 233 5.97E-22 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like CDC59_RS01930 ca9025cf296beba068fbaf4f2efa7fb8 238 Gene3D G3DSA:1.20.1050.10 100 206 1.7E-21 T 29-03-2018 CDC59_RS01930 ca9025cf296beba068fbaf4f2efa7fb8 238 SUPERFAMILY SSF52833 2 81 6.12E-16 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS01930 ca9025cf296beba068fbaf4f2efa7fb8 238 Pfam PF14497 Glutathione S-transferase, C-terminal domain 108 216 2.1E-28 T 29-03-2018 IPR004046 Glutathione S-transferase, C-terminal CDC59_RS08200 63a0a97772362ec55855ab022c4fc892 304 Pfam PF01145 SPFH domain / Band 7 family 24 199 7.2E-28 T 29-03-2018 IPR001107 Band 7 domain CDC59_RS08200 63a0a97772362ec55855ab022c4fc892 304 PIRSF PIRSF005651 1 292 2.2E-88 T 29-03-2018 IPR010200 HflC GO:0016021|GO:0052547 CDC59_RS08200 63a0a97772362ec55855ab022c4fc892 304 SUPERFAMILY SSF117892 54 191 1.02E-25 T 29-03-2018 IPR001107 Band 7 domain CDC59_RS08200 63a0a97772362ec55855ab022c4fc892 304 SMART SM00244 20 185 3.3E-22 T 29-03-2018 IPR001107 Band 7 domain CDC59_RS08200 63a0a97772362ec55855ab022c4fc892 304 TIGRFAM TIGR01932 hflC: HflC protein 142 284 5.4E-47 T 29-03-2018 IPR010200 HflC GO:0016021|GO:0052547 CDC59_RS08205 afbb21894e8adc4d32431d76a7f72c94 66 Pfam PF09838 Uncharacterized protein conserved in bacteria (DUF2065) 9 63 4.9E-23 T 29-03-2018 IPR019201 Protein of unknown function DUF2065 CDC59_RS21625 fe613802e09a53e0521aa7b2a82aa567 216 Pfam PF01810 LysE type translocator 25 210 1.3E-35 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CDC59_RS11955 c70b3dbe4e63eae38786a1834284236a 843 Pfam PF02687 FtsX-like permease family 301 380 3.8E-8 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CDC59_RS23175 219a1e1edd6ff7eeb2c4ce4e33725e79 342 SUPERFAMILY SSF51556 1 337 1.48E-90 T 29-03-2018 IPR032466 Metal-dependent hydrolase CDC59_RS23175 219a1e1edd6ff7eeb2c4ce4e33725e79 342 Pfam PF04909 Amidohydrolase 3 331 4.0E-59 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CDC59_RS23175 219a1e1edd6ff7eeb2c4ce4e33725e79 342 Gene3D G3DSA:3.20.20.140 1 342 2.3E-58 T 29-03-2018 CDC59_RS17320 4c2a1278e025f0a64fee6784521e6b9d 196 SUPERFAMILY SSF88946 15 80 3.34E-8 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS17320 4c2a1278e025f0a64fee6784521e6b9d 196 SUPERFAMILY SSF88659 96 171 1.87E-13 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS17320 4c2a1278e025f0a64fee6784521e6b9d 196 Gene3D G3DSA:1.10.10.10 80 170 6.7E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS17320 4c2a1278e025f0a64fee6784521e6b9d 196 Pfam PF08281 Sigma-70, region 4 116 166 7.8E-13 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS17320 4c2a1278e025f0a64fee6784521e6b9d 196 Pfam PF04542 Sigma-70 region 2 21 81 1.5E-6 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS17320 4c2a1278e025f0a64fee6784521e6b9d 196 Gene3D G3DSA:1.10.1740.10 10 79 1.3E-10 T 29-03-2018 CDC59_RS17320 4c2a1278e025f0a64fee6784521e6b9d 196 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 19 168 6.6E-18 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS09050 b526bc632b13649b27a7ce0620fb7c81 1021 Gene3D G3DSA:3.30.2090.10 179 265 4.1E-14 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS09050 b526bc632b13649b27a7ce0620fb7c81 1021 PRINTS PR00702 Acriflavin resistance protein family signature 607 621 9.3E-39 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS09050 b526bc632b13649b27a7ce0620fb7c81 1021 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 9.3E-39 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS09050 b526bc632b13649b27a7ce0620fb7c81 1021 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 9.3E-39 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS09050 b526bc632b13649b27a7ce0620fb7c81 1021 PRINTS PR00702 Acriflavin resistance protein family signature 328 351 9.3E-39 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS09050 b526bc632b13649b27a7ce0620fb7c81 1021 PRINTS PR00702 Acriflavin resistance protein family signature 538 555 9.3E-39 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS09050 b526bc632b13649b27a7ce0620fb7c81 1021 PRINTS PR00702 Acriflavin resistance protein family signature 355 376 9.3E-39 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS09050 b526bc632b13649b27a7ce0620fb7c81 1021 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 9.3E-39 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS09050 b526bc632b13649b27a7ce0620fb7c81 1021 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 9.3E-39 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS09050 b526bc632b13649b27a7ce0620fb7c81 1021 PRINTS PR00702 Acriflavin resistance protein family signature 383 407 9.3E-39 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS09050 b526bc632b13649b27a7ce0620fb7c81 1021 SUPERFAMILY SSF82866 790 1011 5.1E-41 T 29-03-2018 CDC59_RS09050 b526bc632b13649b27a7ce0620fb7c81 1021 Pfam PF00873 AcrB/AcrD/AcrF family 15 1009 5.5E-221 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS09050 b526bc632b13649b27a7ce0620fb7c81 1021 SUPERFAMILY SSF82714 706 787 1.7E-10 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS09050 b526bc632b13649b27a7ce0620fb7c81 1021 Gene3D G3DSA:3.30.70.1430 553 650 1.8E-14 T 29-03-2018 CDC59_RS09050 b526bc632b13649b27a7ce0620fb7c81 1021 SUPERFAMILY SSF82693 40 125 4.53E-16 T 29-03-2018 CDC59_RS09050 b526bc632b13649b27a7ce0620fb7c81 1021 SUPERFAMILY SSF82866 288 490 3.4E-37 T 29-03-2018 CDC59_RS09050 b526bc632b13649b27a7ce0620fb7c81 1021 Gene3D G3DSA:3.30.2090.10 704 791 1.1E-11 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS09050 b526bc632b13649b27a7ce0620fb7c81 1021 Gene3D G3DSA:3.30.70.1430 40 139 1.5E-17 T 29-03-2018 CDC59_RS09050 b526bc632b13649b27a7ce0620fb7c81 1021 Gene3D G3DSA:1.20.1640.10 278 502 1.0E-38 T 29-03-2018 CDC59_RS09050 b526bc632b13649b27a7ce0620fb7c81 1021 SUPERFAMILY SSF82714 182 263 2.09E-13 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS09050 b526bc632b13649b27a7ce0620fb7c81 1021 SUPERFAMILY SSF82693 135 180 5.23E-21 T 29-03-2018 CDC59_RS09050 b526bc632b13649b27a7ce0620fb7c81 1021 SUPERFAMILY SSF82693 266 322 5.23E-21 T 29-03-2018 CDC59_RS09050 b526bc632b13649b27a7ce0620fb7c81 1021 SUPERFAMILY SSF82693 552 629 1.73E-8 T 29-03-2018 CDC59_RS09050 b526bc632b13649b27a7ce0620fb7c81 1021 Gene3D G3DSA:1.20.1640.10 793 1012 2.1E-34 T 29-03-2018 CDC59_RS22860 bf61ca785fcd3d7bc4f78b70113a9425 283 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 42 267 1.0E-49 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CDC59_RS22860 bf61ca785fcd3d7bc4f78b70113a9425 283 Gene3D G3DSA:3.40.190.10 144 225 7.0E-14 T 29-03-2018 CDC59_RS22860 bf61ca785fcd3d7bc4f78b70113a9425 283 Gene3D G3DSA:3.40.190.10 31 143 3.1E-28 T 29-03-2018 CDC59_RS22860 bf61ca785fcd3d7bc4f78b70113a9425 283 SMART SM00062 41 269 2.1E-44 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CDC59_RS22860 bf61ca785fcd3d7bc4f78b70113a9425 283 SUPERFAMILY SSF53850 15 268 6.44E-51 T 29-03-2018 CDC59_RS00170 bba17b7a404665f460e0193632794701 426 Gene3D G3DSA:3.40.640.10 179 310 3.3E-44 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDC59_RS00170 bba17b7a404665f460e0193632794701 426 PIRSF PIRSF000521 126 426 4.3E-39 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CDC59_RS00170 bba17b7a404665f460e0193632794701 426 PIRSF PIRSF000521 18 134 7.0E-5 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CDC59_RS00170 bba17b7a404665f460e0193632794701 426 Pfam PF00202 Aminotransferase class-III 30 424 1.3E-128 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CDC59_RS00170 bba17b7a404665f460e0193632794701 426 Gene3D G3DSA:3.90.1150.10 311 426 7.4E-31 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS00170 bba17b7a404665f460e0193632794701 426 TIGRFAM TIGR00700 GABAtrnsam: 4-aminobutyrate transaminase 15 424 4.7E-192 T 29-03-2018 IPR004632 4-aminobutyrate aminotransferase, bacterial GO:0003867|GO:0009448 CDC59_RS00170 bba17b7a404665f460e0193632794701 426 SUPERFAMILY SSF53383 28 425 6.46E-133 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS00170 bba17b7a404665f460e0193632794701 426 Gene3D G3DSA:3.90.1150.10 3 171 1.3E-40 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS00170 bba17b7a404665f460e0193632794701 426 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 241 278 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CDC59_RS04885 50be70a43b8b66b05367da46bcd55b5b 190 Pfam PF01613 Flavin reductase like domain 36 184 5.1E-35 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CDC59_RS04885 50be70a43b8b66b05367da46bcd55b5b 190 SMART SM00903 35 184 3.8E-61 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CDC59_RS04885 50be70a43b8b66b05367da46bcd55b5b 190 Gene3D G3DSA:2.30.110.10 24 189 8.6E-42 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CDC59_RS04885 50be70a43b8b66b05367da46bcd55b5b 190 SUPERFAMILY SSF50475 26 181 6.87E-46 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CDC59_RS11225 bc1e7d2b52de20ce299433c00c147097 527 Gene3D G3DSA:3.30.70.270 350 525 2.8E-54 T 29-03-2018 CDC59_RS11225 bc1e7d2b52de20ce299433c00c147097 527 SUPERFAMILY SSF55073 361 511 2.12E-45 T 29-03-2018 IPR029787 Nucleotide cyclase CDC59_RS11225 bc1e7d2b52de20ce299433c00c147097 527 Pfam PF02743 Cache domain 61 258 1.0E-21 T 29-03-2018 IPR033479 Double Cache domain 1 CDC59_RS11225 bc1e7d2b52de20ce299433c00c147097 527 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 352 509 1.1E-46 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS11225 bc1e7d2b52de20ce299433c00c147097 527 SUPERFAMILY SSF103190 76 173 5.49E-6 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CDC59_RS11225 bc1e7d2b52de20ce299433c00c147097 527 SUPERFAMILY SSF103190 185 257 1.1E-10 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CDC59_RS11225 bc1e7d2b52de20ce299433c00c147097 527 SMART SM00267 345 510 2.5E-56 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS11225 bc1e7d2b52de20ce299433c00c147097 527 Pfam PF00990 Diguanylate cyclase, GGDEF domain 356 506 7.5E-41 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS11225 bc1e7d2b52de20ce299433c00c147097 527 Gene3D G3DSA:3.30.450.20 30 153 1.2E-10 T 29-03-2018 CDC59_RS11225 bc1e7d2b52de20ce299433c00c147097 527 Gene3D G3DSA:3.30.450.20 154 263 2.1E-18 T 29-03-2018 CDC59_RS09125 163ba5f6b8518bea6b54edea75b80a96 177 Hamap MF_00163 Peptide deformylase [def]. 1 170 27.072 T 29-03-2018 IPR023635 Peptide deformylase CDC59_RS09125 163ba5f6b8518bea6b54edea75b80a96 177 PRINTS PR01576 Peptide deformylase signature 33 62 3.5E-29 T 29-03-2018 IPR023635 Peptide deformylase CDC59_RS09125 163ba5f6b8518bea6b54edea75b80a96 177 PRINTS PR01576 Peptide deformylase signature 128 157 3.5E-29 T 29-03-2018 IPR023635 Peptide deformylase CDC59_RS09125 163ba5f6b8518bea6b54edea75b80a96 177 PRINTS PR01576 Peptide deformylase signature 109 127 3.5E-29 T 29-03-2018 IPR023635 Peptide deformylase CDC59_RS09125 163ba5f6b8518bea6b54edea75b80a96 177 PRINTS PR01576 Peptide deformylase signature 97 108 3.5E-29 T 29-03-2018 IPR023635 Peptide deformylase CDC59_RS09125 163ba5f6b8518bea6b54edea75b80a96 177 Gene3D G3DSA:3.90.45.10 1 167 4.2E-55 T 29-03-2018 IPR023635 Peptide deformylase CDC59_RS09125 163ba5f6b8518bea6b54edea75b80a96 177 Pfam PF01327 Polypeptide deformylase 3 157 1.9E-48 T 29-03-2018 IPR023635 Peptide deformylase CDC59_RS09125 163ba5f6b8518bea6b54edea75b80a96 177 PIRSF PIRSF004749 1 167 1.8E-50 T 29-03-2018 IPR023635 Peptide deformylase CDC59_RS09125 163ba5f6b8518bea6b54edea75b80a96 177 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 5 157 6.0E-35 T 29-03-2018 IPR023635 Peptide deformylase CDC59_RS09125 163ba5f6b8518bea6b54edea75b80a96 177 SUPERFAMILY SSF56420 1 165 3.01E-58 T 29-03-2018 IPR023635 Peptide deformylase CDC59_RS00670 6056752353ad9f0e77db699152d9a15f 334 Gene3D G3DSA:3.40.50.720 136 315 4.0E-19 T 29-03-2018 CDC59_RS00670 6056752353ad9f0e77db699152d9a15f 334 SUPERFAMILY SSF51735 2 331 1.42E-61 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS00670 6056752353ad9f0e77db699152d9a15f 334 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 13 257 7.6E-34 T 29-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CDC59_RS00670 6056752353ad9f0e77db699152d9a15f 334 Gene3D G3DSA:3.30.1780.10 1 135 2.7E-36 T 29-03-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 CDC59_RS00670 6056752353ad9f0e77db699152d9a15f 334 PIRSF PIRSF001439 1 332 3.8E-50 T 29-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CDC59_RS22375 a0c77b6393b3aecbb566e15968689c63 197 Gene3D G3DSA:3.80.10.10 1 185 2.3E-5 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like CDC59_RS14805 a2448cf9dd6b448f20f077e50159b4e1 299 Gene3D G3DSA:1.10.10.10 10 87 7.1E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS14805 a2448cf9dd6b448f20f077e50159b4e1 299 Gene3D G3DSA:3.30.450.40 99 275 1.5E-38 T 29-03-2018 IPR029016 GAF domain-like CDC59_RS14805 a2448cf9dd6b448f20f077e50159b4e1 299 SUPERFAMILY SSF46785 26 98 2.26E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS14805 a2448cf9dd6b448f20f077e50159b4e1 299 Pfam PF01614 Bacterial transcriptional regulator 143 268 1.4E-10 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CDC59_RS14805 a2448cf9dd6b448f20f077e50159b4e1 299 Pfam PF09339 IclR helix-turn-helix domain 28 79 2.4E-14 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CDC59_RS14805 a2448cf9dd6b448f20f077e50159b4e1 299 SUPERFAMILY SSF55781 84 274 4.97E-34 T 29-03-2018 IPR029016 GAF domain-like CDC59_RS14805 a2448cf9dd6b448f20f077e50159b4e1 299 SMART SM00346 26 116 2.8E-17 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CDC59_RS23035 59b16f62e87caed9dd2e6f1c7cbc1a8f 348 SMART SM00354 24 94 2.1E-18 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDC59_RS23035 59b16f62e87caed9dd2e6f1c7cbc1a8f 348 Gene3D G3DSA:3.40.50.2300 77 191 1.8E-23 T 29-03-2018 CDC59_RS23035 59b16f62e87caed9dd2e6f1c7cbc1a8f 348 Pfam PF13377 Periplasmic binding protein-like domain 192 347 1.7E-27 T 29-03-2018 CDC59_RS23035 59b16f62e87caed9dd2e6f1c7cbc1a8f 348 Pfam PF00356 Bacterial regulatory proteins, lacI family 26 71 2.3E-14 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDC59_RS23035 59b16f62e87caed9dd2e6f1c7cbc1a8f 348 SUPERFAMILY SSF53822 82 345 5.24E-51 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CDC59_RS23035 59b16f62e87caed9dd2e6f1c7cbc1a8f 348 ProSitePatterns PS00356 LacI-type HTH domain signature. 27 45 - T 29-03-2018 CDC59_RS23035 59b16f62e87caed9dd2e6f1c7cbc1a8f 348 Gene3D G3DSA:3.40.50.2300 192 348 4.0E-37 T 29-03-2018 CDC59_RS23035 59b16f62e87caed9dd2e6f1c7cbc1a8f 348 Gene3D G3DSA:1.10.260.40 25 76 1.1E-17 T 29-03-2018 CDC59_RS23035 59b16f62e87caed9dd2e6f1c7cbc1a8f 348 SUPERFAMILY SSF47413 24 82 1.41E-15 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDC59_RS14085 d22144739945afe30e1dde3c910d3c04 123 Gene3D G3DSA:1.10.1200.10 38 122 1.4E-8 T 29-03-2018 CDC59_RS14085 d22144739945afe30e1dde3c910d3c04 123 SUPERFAMILY SSF47336 38 120 4.58E-8 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS16090 5fbda78e5b70e307fd16db75707ef85d 201 Gene3D G3DSA:3.40.50.2300 3 133 6.5E-33 T 29-03-2018 CDC59_RS16090 5fbda78e5b70e307fd16db75707ef85d 201 ProSitePatterns PS00622 LuxR-type HTH domain signature. 153 180 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS16090 5fbda78e5b70e307fd16db75707ef85d 201 Gene3D G3DSA:1.10.10.10 139 199 1.2E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS16090 5fbda78e5b70e307fd16db75707ef85d 201 SUPERFAMILY SSF52172 6 140 1.57E-38 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS16090 5fbda78e5b70e307fd16db75707ef85d 201 Pfam PF00072 Response regulator receiver domain 8 120 8.0E-23 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS16090 5fbda78e5b70e307fd16db75707ef85d 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 139 153 3.2E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS16090 5fbda78e5b70e307fd16db75707ef85d 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 169 3.2E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS16090 5fbda78e5b70e307fd16db75707ef85d 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 181 3.2E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS16090 5fbda78e5b70e307fd16db75707ef85d 201 Pfam PF00196 Bacterial regulatory proteins, luxR family 138 193 1.7E-18 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS16090 5fbda78e5b70e307fd16db75707ef85d 201 SMART SM00448 6 120 1.4E-35 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS16090 5fbda78e5b70e307fd16db75707ef85d 201 SMART SM00421 136 193 3.8E-22 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS16090 5fbda78e5b70e307fd16db75707ef85d 201 SUPERFAMILY SSF46894 128 199 5.78E-20 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CDC59_RS08400 bef7ff30b5d011d69e4451a2f7770cf8 158 SUPERFAMILY SSF52821 21 155 1.78E-16 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS08400 bef7ff30b5d011d69e4451a2f7770cf8 158 Gene3D G3DSA:3.40.250.10 5 158 4.9E-16 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS08400 bef7ff30b5d011d69e4451a2f7770cf8 158 SMART SM00450 31 141 2.1E-4 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS22510 6c527679e926b3128ba7d7e66e4b6fbd 344 Gene3D G3DSA:1.10.1040.10 187 332 2.5E-29 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CDC59_RS22510 6c527679e926b3128ba7d7e66e4b6fbd 344 SUPERFAMILY SSF48179 176 316 1.73E-22 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CDC59_RS22510 6c527679e926b3128ba7d7e66e4b6fbd 344 Gene3D G3DSA:3.40.50.720 3 186 5.3E-29 T 29-03-2018 CDC59_RS22510 6c527679e926b3128ba7d7e66e4b6fbd 344 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 3 317 5.1E-65 T 29-03-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CDC59_RS22510 6c527679e926b3128ba7d7e66e4b6fbd 344 Pfam PF02558 Ketopantoate reductase PanE/ApbA 5 155 3.0E-40 T 29-03-2018 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CDC59_RS22510 6c527679e926b3128ba7d7e66e4b6fbd 344 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 176 315 1.3E-19 T 29-03-2018 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CDC59_RS22510 6c527679e926b3128ba7d7e66e4b6fbd 344 SUPERFAMILY SSF51735 3 125 7.58E-17 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS02515 ef8a56ad27e73f5848092edf983db95a 344 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 67 337 9.7E-52 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CDC59_RS02515 ef8a56ad27e73f5848092edf983db95a 344 Gene3D G3DSA:3.40.190.10 142 269 3.1E-5 T 29-03-2018 CDC59_RS02515 ef8a56ad27e73f5848092edf983db95a 344 PIRSF PIRSF017082 13 340 1.4E-50 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CDC59_RS03880 aa8386d8d1ed64da105019b3b22443e6 146 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 14 36 5.2E-9 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS03880 aa8386d8d1ed64da105019b3b22443e6 146 PRINTS PR00813 Bacterial general secretion pathway protein G signature 51 69 1.2E-8 T 29-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 CDC59_RS03880 aa8386d8d1ed64da105019b3b22443e6 146 PRINTS PR00813 Bacterial general secretion pathway protein G signature 15 40 1.2E-8 T 29-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 CDC59_RS03880 aa8386d8d1ed64da105019b3b22443e6 146 Pfam PF16732 Type IV minor pilin ComP, DNA uptake sequence receptor 37 127 7.8E-20 T 29-03-2018 IPR031982 Type IV minor pilin ComP CDC59_RS03880 aa8386d8d1ed64da105019b3b22443e6 146 Gene3D G3DSA:3.30.700.10 16 145 4.0E-21 T 29-03-2018 CDC59_RS03880 aa8386d8d1ed64da105019b3b22443e6 146 Pfam PF07963 Prokaryotic N-terminal methylation motif 11 36 7.5E-9 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS03880 aa8386d8d1ed64da105019b3b22443e6 146 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 14 34 - T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS03880 aa8386d8d1ed64da105019b3b22443e6 146 SUPERFAMILY SSF54523 16 134 9.42E-23 T 29-03-2018 CDC59_RS07720 daeffeea166bff843a77eaf56fa30540 305 PRINTS PR00111 Alpha/beta hydrolase fold signature 111 124 9.6E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS07720 daeffeea166bff843a77eaf56fa30540 305 PRINTS PR00111 Alpha/beta hydrolase fold signature 125 138 9.6E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS07720 daeffeea166bff843a77eaf56fa30540 305 PRINTS PR00111 Alpha/beta hydrolase fold signature 61 76 9.6E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS07720 daeffeea166bff843a77eaf56fa30540 305 Gene3D G3DSA:3.40.50.1820 11 301 2.5E-46 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS07720 daeffeea166bff843a77eaf56fa30540 305 Pfam PF12697 Alpha/beta hydrolase family 39 296 4.4E-22 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS07720 daeffeea166bff843a77eaf56fa30540 305 SUPERFAMILY SSF53474 14 303 5.05E-51 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS05215 f1573bfb2fd215f026b676ef90b7acd6 122 Pfam PF13560 Helix-turn-helix domain 3 51 4.7E-7 T 29-03-2018 CDC59_RS05215 f1573bfb2fd215f026b676ef90b7acd6 122 SUPERFAMILY SSF47413 1 64 2.51E-11 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDC59_RS05215 f1573bfb2fd215f026b676ef90b7acd6 122 SMART SM00530 6 60 3.1E-5 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDC59_RS05215 f1573bfb2fd215f026b676ef90b7acd6 122 Gene3D G3DSA:1.10.260.40 1 121 2.9E-13 T 29-03-2018 CDC59_RS14560 2cf17d3c1102d55c7985d9e213986651 517 SUPERFAMILY SSF111352 85 496 1.96E-126 T 29-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 CDC59_RS14560 2cf17d3c1102d55c7985d9e213986651 517 TIGRFAM TIGR00836 amt: ammonium transporter 88 515 5.2E-135 T 29-03-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 CDC59_RS14560 2cf17d3c1102d55c7985d9e213986651 517 Pfam PF00909 Ammonium Transporter Family 90 515 2.3E-122 T 29-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 CDC59_RS14560 2cf17d3c1102d55c7985d9e213986651 517 Gene3D G3DSA:1.10.3430.10 80 496 2.5E-133 T 29-03-2018 CDC59_RS14560 2cf17d3c1102d55c7985d9e213986651 517 ProSitePatterns PS01219 Ammonium transporters signature. 264 289 - T 29-03-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 CDC59_RS00280 757e2156f804d0fa7c82e72ac12c6015 328 Pfam PF05598 Transposase domain (DUF772) 51 126 3.1E-23 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS00280 757e2156f804d0fa7c82e72ac12c6015 328 Pfam PF01609 Transposase DDE domain 138 312 2.4E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS05115 057680b75654e4631ed137d7fd39a3ae 75 Pfam PF01206 Sulfurtransferase TusA 5 74 8.8E-26 T 29-03-2018 IPR001455 TusA-like domain CDC59_RS05115 057680b75654e4631ed137d7fd39a3ae 75 SUPERFAMILY SSF64307 3 74 6.02E-26 T 29-03-2018 IPR001455 TusA-like domain CDC59_RS05115 057680b75654e4631ed137d7fd39a3ae 75 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 7 31 - T 29-03-2018 IPR001455 TusA-like domain CDC59_RS05115 057680b75654e4631ed137d7fd39a3ae 75 Gene3D G3DSA:3.30.110.40 1 75 2.2E-29 T 29-03-2018 IPR001455 TusA-like domain CDC59_RS09225 d3c403177b9f3f58679a095e7160e9c6 259 SUPERFAMILY SSF55315 2 104 1.93E-17 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like CDC59_RS09225 d3c403177b9f3f58679a095e7160e9c6 259 SUPERFAMILY SSF75217 108 257 1.83E-40 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases CDC59_RS09225 d3c403177b9f3f58679a095e7160e9c6 259 Gene3D G3DSA:3.40.1280.10 107 257 3.6E-42 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CDC59_RS09225 d3c403177b9f3f58679a095e7160e9c6 259 Pfam PF00588 SpoU rRNA Methylase family 115 250 1.5E-31 T 29-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CDC59_RS09225 d3c403177b9f3f58679a095e7160e9c6 259 Gene3D G3DSA:3.30.1330.30 3 105 6.5E-15 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like CDC59_RS15880 3181fea765f50f2d6fb3fc3941a5fa70 508 SUPERFAMILY SSF56176 19 202 9.35E-31 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CDC59_RS15880 3181fea765f50f2d6fb3fc3941a5fa70 508 Gene3D G3DSA:3.30.465.10 89 228 5.3E-25 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CDC59_RS15880 3181fea765f50f2d6fb3fc3941a5fa70 508 Gene3D G3DSA:3.30.43.10 4 84 1.3E-10 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CDC59_RS15880 3181fea765f50f2d6fb3fc3941a5fa70 508 Pfam PF01565 FAD binding domain 34 160 2.7E-14 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CDC59_RS15880 3181fea765f50f2d6fb3fc3941a5fa70 508 Pfam PF08031 Berberine and berberine like 458 507 1.3E-14 T 29-03-2018 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 CDC59_RS04425 c42c47b935802a4e81843b2913ec410f 252 SUPERFAMILY SSF55120 68 234 2.08E-42 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDC59_RS04425 c42c47b935802a4e81843b2913ec410f 252 Gene3D G3DSA:3.10.290.10 3 64 1.3E-10 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CDC59_RS04425 c42c47b935802a4e81843b2913ec410f 252 Gene3D G3DSA:3.30.2350.10 65 248 2.4E-32 T 29-03-2018 CDC59_RS04425 c42c47b935802a4e81843b2913ec410f 252 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 73 231 1.3E-41 T 29-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 CDC59_RS04425 c42c47b935802a4e81843b2913ec410f 252 SUPERFAMILY SSF55174 8 74 4.91E-8 T 29-03-2018 CDC59_RS04425 c42c47b935802a4e81843b2913ec410f 252 Pfam PF01479 S4 domain 12 49 2.2E-5 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CDC59_RS04425 c42c47b935802a4e81843b2913ec410f 252 Pfam PF00849 RNA pseudouridylate synthase 69 200 2.2E-14 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDC59_RS04425 c42c47b935802a4e81843b2913ec410f 252 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 107 121 - T 29-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 CDC59_RS15915 a17c6221c066574fe74300ad2bdfef1d 432 Gene3D G3DSA:3.30.1220.10 244 385 2.8E-32 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CDC59_RS15915 a17c6221c066574fe74300ad2bdfef1d 432 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 6 214 4.1E-58 T 29-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CDC59_RS15915 a17c6221c066574fe74300ad2bdfef1d 432 SUPERFAMILY SSF90002 260 384 1.57E-20 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CDC59_RS15915 a17c6221c066574fe74300ad2bdfef1d 432 Gene3D G3DSA:3.40.50.300 2 233 2.0E-55 T 29-03-2018 CDC59_RS15915 a17c6221c066574fe74300ad2bdfef1d 432 SMART SM00833 260 384 1.5E-50 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CDC59_RS15915 a17c6221c066574fe74300ad2bdfef1d 432 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 260 384 1.6E-29 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CDC59_RS15915 a17c6221c066574fe74300ad2bdfef1d 432 SUPERFAMILY SSF52540 3 302 1.75E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS00660 17487a725cb708ef80b0831e81f1eacd 158 SUPERFAMILY SSF46785 4 63 2.03E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS00660 17487a725cb708ef80b0831e81f1eacd 158 Pfam PF01037 Lrp/AsnC ligand binding domain 72 142 2.8E-22 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CDC59_RS00660 17487a725cb708ef80b0831e81f1eacd 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 3.5E-8 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CDC59_RS00660 17487a725cb708ef80b0831e81f1eacd 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 3.5E-8 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CDC59_RS00660 17487a725cb708ef80b0831e81f1eacd 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 3.5E-8 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CDC59_RS00660 17487a725cb708ef80b0831e81f1eacd 158 Gene3D G3DSA:1.10.10.10 1 55 1.8E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS00660 17487a725cb708ef80b0831e81f1eacd 158 Pfam PF13404 AsnC-type helix-turn-helix domain 4 45 7.5E-15 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CDC59_RS00660 17487a725cb708ef80b0831e81f1eacd 158 SUPERFAMILY SSF54909 64 153 1.61E-20 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CDC59_RS00660 17487a725cb708ef80b0831e81f1eacd 158 SMART SM00344 4 113 1.4E-31 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CDC59_RS00660 17487a725cb708ef80b0831e81f1eacd 158 Gene3D G3DSA:3.30.70.920 56 154 2.1E-26 T 29-03-2018 CDC59_RS21285 76f9657a2e173319d462804c0cbf46e7 413 Pfam PF02264 LamB porin 31 413 7.0E-65 T 29-03-2018 IPR003192 Porin, LamB type GO:0006810|GO:0016020 CDC59_RS21285 76f9657a2e173319d462804c0cbf46e7 413 Gene3D G3DSA:2.40.170.10 27 413 4.8E-69 T 29-03-2018 IPR003192 Porin, LamB type GO:0006810|GO:0016020 CDC59_RS21285 76f9657a2e173319d462804c0cbf46e7 413 ProDom PD008788 PORIN MEMBRANE PRECURSOR SIGNAL MALTOPORIN OUTER ION TRANSMEMBRANE RECEPTOR LAMB 53 377 2.0E-43 T 29-03-2018 IPR003192 Porin, LamB type GO:0006810|GO:0016020 CDC59_RS21285 76f9657a2e173319d462804c0cbf46e7 413 SUPERFAMILY SSF56935 29 413 1.53E-77 T 29-03-2018 CDC59_RS04445 ed9a216d5a038edd3c7deba1d2000eb3 323 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 171 315 8.8E-24 T 29-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 CDC59_RS04445 ed9a216d5a038edd3c7deba1d2000eb3 323 SUPERFAMILY SSF53671 16 321 3.27E-96 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CDC59_RS04445 ed9a216d5a038edd3c7deba1d2000eb3 323 Gene3D G3DSA:3.40.50.1370 178 321 4.4E-46 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CDC59_RS04445 ed9a216d5a038edd3c7deba1d2000eb3 323 PRINTS PR00101 Aspartate carbamoyltransferase signature 55 77 2.4E-28 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CDC59_RS04445 ed9a216d5a038edd3c7deba1d2000eb3 323 PRINTS PR00101 Aspartate carbamoyltransferase signature 150 167 2.4E-28 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CDC59_RS04445 ed9a216d5a038edd3c7deba1d2000eb3 323 PRINTS PR00101 Aspartate carbamoyltransferase signature 235 244 2.4E-28 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CDC59_RS04445 ed9a216d5a038edd3c7deba1d2000eb3 323 PRINTS PR00101 Aspartate carbamoyltransferase signature 276 281 2.4E-28 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CDC59_RS04445 ed9a216d5a038edd3c7deba1d2000eb3 323 PRINTS PR00101 Aspartate carbamoyltransferase signature 300 314 2.4E-28 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CDC59_RS04445 ed9a216d5a038edd3c7deba1d2000eb3 323 PRINTS PR00101 Aspartate carbamoyltransferase signature 93 102 2.4E-28 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CDC59_RS04445 ed9a216d5a038edd3c7deba1d2000eb3 323 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 16 321 41.093 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CDC59_RS04445 ed9a216d5a038edd3c7deba1d2000eb3 323 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 65 72 - T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CDC59_RS04445 ed9a216d5a038edd3c7deba1d2000eb3 323 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 17 318 8.1E-93 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CDC59_RS04445 ed9a216d5a038edd3c7deba1d2000eb3 323 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 284 307 2.2E-17 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CDC59_RS04445 ed9a216d5a038edd3c7deba1d2000eb3 323 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 151 162 2.2E-17 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CDC59_RS04445 ed9a216d5a038edd3c7deba1d2000eb3 323 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 272 281 2.2E-17 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CDC59_RS04445 ed9a216d5a038edd3c7deba1d2000eb3 323 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 65 84 2.2E-17 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CDC59_RS04445 ed9a216d5a038edd3c7deba1d2000eb3 323 Gene3D G3DSA:3.40.50.1370 8 177 7.6E-60 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CDC59_RS04445 ed9a216d5a038edd3c7deba1d2000eb3 323 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 17 163 1.4E-40 T 29-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 CDC59_RS02480 c62cfe652e8c8adb53cafa615a9dca8d 179 Pfam PF01202 Shikimate kinase 1 157 6.1E-54 T 29-03-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CDC59_RS02480 c62cfe652e8c8adb53cafa615a9dca8d 179 SUPERFAMILY SSF52540 1 156 4.04E-30 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS02480 c62cfe652e8c8adb53cafa615a9dca8d 179 Hamap MF_00109 Shikimate kinase [aroK]. 1 158 25.548 T 29-03-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CDC59_RS02480 c62cfe652e8c8adb53cafa615a9dca8d 179 PRINTS PR01100 Shikimate kinase family signature 47 55 1.6E-12 T 29-03-2018 CDC59_RS02480 c62cfe652e8c8adb53cafa615a9dca8d 179 PRINTS PR01100 Shikimate kinase family signature 65 74 1.6E-12 T 29-03-2018 CDC59_RS02480 c62cfe652e8c8adb53cafa615a9dca8d 179 PRINTS PR01100 Shikimate kinase family signature 19 32 1.6E-12 T 29-03-2018 CDC59_RS02480 c62cfe652e8c8adb53cafa615a9dca8d 179 PRINTS PR01100 Shikimate kinase family signature 86 103 1.6E-12 T 29-03-2018 CDC59_RS02480 c62cfe652e8c8adb53cafa615a9dca8d 179 ProSitePatterns PS01128 Shikimate kinase signature. 48 73 - T 29-03-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CDC59_RS02480 c62cfe652e8c8adb53cafa615a9dca8d 179 Gene3D G3DSA:3.40.50.300 1 160 4.7E-30 T 29-03-2018 CDC59_RS10370 2417a5cb8fe9b1afbce6aaa825707dd4 780 SUPERFAMILY SSF158832 6 329 6.41E-116 T 29-03-2018 CDC59_RS10370 2417a5cb8fe9b1afbce6aaa825707dd4 780 Gene3D G3DSA:1.10.3500.10 363 511 3.9E-41 T 29-03-2018 IPR023323 Tex-like domain CDC59_RS10370 2417a5cb8fe9b1afbce6aaa825707dd4 780 Pfam PF00575 S1 RNA binding domain 662 733 2.4E-20 T 29-03-2018 IPR003029 S1 domain GO:0003676 CDC59_RS10370 2417a5cb8fe9b1afbce6aaa825707dd4 780 Gene3D G3DSA:1.10.3500.10 107 362 1.2E-80 T 29-03-2018 IPR023323 Tex-like domain CDC59_RS10370 2417a5cb8fe9b1afbce6aaa825707dd4 780 SMART SM00732 334 437 1.1E-32 T 29-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 CDC59_RS10370 2417a5cb8fe9b1afbce6aaa825707dd4 780 Pfam PF12836 Helix-hairpin-helix motif 504 568 4.9E-28 T 29-03-2018 CDC59_RS10370 2417a5cb8fe9b1afbce6aaa825707dd4 780 Pfam PF16921 Tex protein YqgF-like domain 334 464 9.5E-53 T 29-03-2018 IPR032639 Tex protein, YqgF-like domain CDC59_RS10370 2417a5cb8fe9b1afbce6aaa825707dd4 780 Gene3D G3DSA:1.10.150.310 512 643 5.9E-42 T 29-03-2018 CDC59_RS10370 2417a5cb8fe9b1afbce6aaa825707dd4 780 SUPERFAMILY SSF47781 483 571 3.93E-29 T 29-03-2018 IPR010994 RuvA domain 2-like CDC59_RS10370 2417a5cb8fe9b1afbce6aaa825707dd4 780 SUPERFAMILY SSF47781 573 645 5.56E-19 T 29-03-2018 IPR010994 RuvA domain 2-like CDC59_RS10370 2417a5cb8fe9b1afbce6aaa825707dd4 780 Gene3D G3DSA:2.40.50.140 644 739 1.1E-24 T 29-03-2018 CDC59_RS10370 2417a5cb8fe9b1afbce6aaa825707dd4 780 SUPERFAMILY SSF50249 650 737 3.88E-24 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDC59_RS10370 2417a5cb8fe9b1afbce6aaa825707dd4 780 SMART SM00316 662 733 2.2E-24 T 29-03-2018 IPR022967 RNA-binding domain, S1 CDC59_RS10370 2417a5cb8fe9b1afbce6aaa825707dd4 780 SUPERFAMILY SSF53098 330 482 1.29E-49 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDC59_RS10370 2417a5cb8fe9b1afbce6aaa825707dd4 780 Gene3D G3DSA:1.10.10.650 6 106 4.4E-35 T 29-03-2018 IPR023319 Tex-like protein, HTH domain CDC59_RS10370 2417a5cb8fe9b1afbce6aaa825707dd4 780 Pfam PF09371 Tex-like protein N-terminal domain 13 200 1.6E-70 T 29-03-2018 IPR018974 Tex-like protein, N-terminal CDC59_RS14105 0e40eb1767ae18732ac56537bab4ff91 215 SUPERFAMILY SSF89392 50 211 1.22E-17 T 29-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX CDC59_RS14105 0e40eb1767ae18732ac56537bab4ff91 215 Gene3D G3DSA:2.50.20.10 46 212 2.3E-21 T 29-03-2018 CDC59_RS14105 0e40eb1767ae18732ac56537bab4ff91 215 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 62 210 3.4E-9 T 29-03-2018 IPR004564 Outer membrane lipoprotein carrier protein LolA-like CDC59_RS11085 0fa6b9875e1f271ae7d98cc0405a7009 85 Pfam PF07369 Protein of unknown function (DUF1488) 17 68 1.4E-4 T 29-03-2018 IPR009962 Protein of unknown function DUF1488 CDC59_RS11085 0fa6b9875e1f271ae7d98cc0405a7009 85 Gene3D G3DSA:3.30.160.140 5 73 4.5E-6 T 29-03-2018 IPR009962 Protein of unknown function DUF1488 CDC59_RS15720 66e37fa878ac0311fb949ae2e414f5e3 299 SUPERFAMILY SSF53697 111 263 1.36E-17 T 29-03-2018 CDC59_RS15720 66e37fa878ac0311fb949ae2e414f5e3 299 Gene3D G3DSA:1.10.10.10 2 80 8.1E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS15720 66e37fa878ac0311fb949ae2e414f5e3 299 Gene3D G3DSA:3.40.50.10490 98 287 1.2E-18 T 29-03-2018 CDC59_RS15720 66e37fa878ac0311fb949ae2e414f5e3 299 SUPERFAMILY SSF46689 5 80 3.4E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS15720 66e37fa878ac0311fb949ae2e414f5e3 299 Pfam PF01380 SIS domain 133 256 2.9E-13 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CDC59_RS00505 26972c4d1c7b4e723487158b129453ef 403 Gene3D G3DSA:3.20.20.450 152 403 6.0E-65 T 29-03-2018 IPR001633 EAL domain CDC59_RS00505 26972c4d1c7b4e723487158b129453ef 403 SMART SM00448 7 160 3.5E-5 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS00505 26972c4d1c7b4e723487158b129453ef 403 SUPERFAMILY SSF52172 7 79 1.38E-17 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS00505 26972c4d1c7b4e723487158b129453ef 403 SMART SM00052 144 395 2.1E-58 T 29-03-2018 IPR001633 EAL domain CDC59_RS00505 26972c4d1c7b4e723487158b129453ef 403 Pfam PF00563 EAL domain 165 390 5.2E-57 T 29-03-2018 IPR001633 EAL domain CDC59_RS00505 26972c4d1c7b4e723487158b129453ef 403 SUPERFAMILY SSF141868 165 399 7.32E-61 T 29-03-2018 IPR001633 EAL domain CDC59_RS00505 26972c4d1c7b4e723487158b129453ef 403 Gene3D G3DSA:3.40.50.2300 2 114 1.0E-17 T 29-03-2018 CDC59_RS00505 26972c4d1c7b4e723487158b129453ef 403 Pfam PF00072 Response regulator receiver domain 9 78 2.6E-14 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS12090 5b97564b3c6b7a3c49baaf35917fd282 208 Gene3D G3DSA:3.40.50.150 2 202 5.7E-25 T 29-03-2018 CDC59_RS12090 5b97564b3c6b7a3c49baaf35917fd282 208 SUPERFAMILY SSF53335 2 204 5.17E-25 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS12090 5b97564b3c6b7a3c49baaf35917fd282 208 Pfam PF13649 Methyltransferase domain 41 130 5.2E-16 T 29-03-2018 CDC59_RS07360 f58111da35f9dbf4d9fa45fc51347cbe 297 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 157 169 8.9E-25 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CDC59_RS07360 f58111da35f9dbf4d9fa45fc51347cbe 297 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 247 266 8.9E-25 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CDC59_RS07360 f58111da35f9dbf4d9fa45fc51347cbe 297 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 93 109 8.9E-25 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CDC59_RS07360 f58111da35f9dbf4d9fa45fc51347cbe 297 ProSitePatterns PS00760 Signal peptidases I lysine active site. 159 171 - T 29-03-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 CDC59_RS07360 f58111da35f9dbf4d9fa45fc51347cbe 297 Pfam PF10502 Signal peptidase, peptidase S26 245 284 2.0E-6 T 29-03-2018 IPR019533 Peptidase S26 CDC59_RS07360 f58111da35f9dbf4d9fa45fc51347cbe 297 SUPERFAMILY SSF51306 91 293 4.6E-71 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CDC59_RS07360 f58111da35f9dbf4d9fa45fc51347cbe 297 Gene3D G3DSA:2.10.109.10 89 296 4.1E-59 T 29-03-2018 CDC59_RS07360 f58111da35f9dbf4d9fa45fc51347cbe 297 ProSitePatterns PS00501 Signal peptidases I serine active site. 102 109 - T 29-03-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 CDC59_RS07360 f58111da35f9dbf4d9fa45fc51347cbe 297 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 78 286 7.2E-53 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CDC59_RS07360 f58111da35f9dbf4d9fa45fc51347cbe 297 ProSitePatterns PS00761 Signal peptidases I signature 3. 252 265 - T 29-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 CDC59_RS07360 f58111da35f9dbf4d9fa45fc51347cbe 297 Pfam PF00717 Peptidase S24-like 99 180 1.1E-21 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CDC59_RS09210 bc028d2b81bbeb57c4ea2fc1632e4773 271 Gene3D G3DSA:1.20.1180.10 200 271 2.0E-22 T 29-03-2018 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 CDC59_RS09210 bc028d2b81bbeb57c4ea2fc1632e4773 271 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 20 51 2.5E-6 T 29-03-2018 IPR001451 Hexapeptide repeat CDC59_RS09210 bc028d2b81bbeb57c4ea2fc1632e4773 271 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 108 142 1.1E-8 T 29-03-2018 IPR001451 Hexapeptide repeat CDC59_RS09210 bc028d2b81bbeb57c4ea2fc1632e4773 271 SUPERFAMILY SSF51161 4 270 3.87E-73 T 29-03-2018 IPR011004 Trimeric LpxA-like CDC59_RS09210 bc028d2b81bbeb57c4ea2fc1632e4773 271 Hamap MF_00387 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase [lpxA]. 4 271 45.573 T 29-03-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 CDC59_RS09210 bc028d2b81bbeb57c4ea2fc1632e4773 271 Gene3D G3DSA:2.160.10.10 1 197 3.7E-44 T 29-03-2018 CDC59_RS09210 bc028d2b81bbeb57c4ea2fc1632e4773 271 Pfam PF13720 Udp N-acetylglucosamine O-acyltransferase; Domain 2 179 270 2.2E-26 T 29-03-2018 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 CDC59_RS09210 bc028d2b81bbeb57c4ea2fc1632e4773 271 TIGRFAM TIGR01852 lipid_A_lpxA: acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase 7 270 5.0E-101 T 29-03-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 CDC59_RS09210 bc028d2b81bbeb57c4ea2fc1632e4773 271 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 152 180 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CDC59_RS09210 bc028d2b81bbeb57c4ea2fc1632e4773 271 PIRSF PIRSF000456 3 271 1.4E-100 T 29-03-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 CDC59_RS10315 c5dbe7d562df2b0e32c57d0775c9cc17 185 TIGRFAM TIGR01848 PHA_reg_PhaR: polyhydroxyalkanoate synthesis repressor PhaR 10 115 1.9E-46 T 29-03-2018 IPR010134 Polyhydroxyalkanoate synthesis repressor PhaR GO:0006355 CDC59_RS10315 c5dbe7d562df2b0e32c57d0775c9cc17 185 Pfam PF05233 PHB accumulation regulatory domain 75 113 1.3E-18 T 29-03-2018 IPR007897 PHB accumulation regulatory CDC59_RS10315 c5dbe7d562df2b0e32c57d0775c9cc17 185 Pfam PF05233 PHB accumulation regulatory domain 126 165 2.4E-17 T 29-03-2018 IPR007897 PHB accumulation regulatory CDC59_RS10315 c5dbe7d562df2b0e32c57d0775c9cc17 185 Pfam PF07879 PHB/PHA accumulation regulator DNA-binding domain 11 70 6.7E-32 T 29-03-2018 IPR012909 PHA accumulation regulator DNA-binding, N-terminal CDC59_RS04270 96df890422328c0f17862b9db81c4243 105 Gene3D G3DSA:2.60.120.10 4 104 1.6E-41 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CDC59_RS04270 96df890422328c0f17862b9db81c4243 105 Hamap MF_01537 UPF0345 protein YaiE [yaiE]. 12 105 27.031 T 29-03-2018 IPR009664 Pyrimidine/purine nucleoside phosphorylase CDC59_RS04270 96df890422328c0f17862b9db81c4243 105 SUPERFAMILY SSF51182 13 104 5.85E-35 T 29-03-2018 IPR011051 RmlC-like cupin domain CDC59_RS04270 96df890422328c0f17862b9db81c4243 105 Pfam PF06865 Protein of unknown function (DUF1255) 14 104 1.1E-37 T 29-03-2018 IPR009664 Pyrimidine/purine nucleoside phosphorylase CDC59_RS08385 5212cfb25774cd1efc65b0d2c1000b67 324 Pfam PF04116 Fatty acid hydroxylase superfamily 135 279 1.6E-33 T 29-03-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 CDC59_RS03685 c259d241db933fbcb764232f0ab15310 532 Gene3D G3DSA:3.20.20.70 126 498 9.5E-96 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS03685 c259d241db933fbcb764232f0ab15310 532 PIRSF PIRSF500060 9 527 7.3E-240 T 29-03-2018 IPR027283 Glutamate synthase large subunit-like protein, bacteria CDC59_RS03685 c259d241db933fbcb764232f0ab15310 532 PIRSF PIRSF006429 5 530 2.0E-160 T 29-03-2018 IPR024188 Glutamate synthase large subunit-like protein CDC59_RS03685 c259d241db933fbcb764232f0ab15310 532 SUPERFAMILY SSF51395 23 489 1.67E-132 T 29-03-2018 CDC59_RS03685 c259d241db933fbcb764232f0ab15310 532 Pfam PF01645 Conserved region in glutamate synthase 153 470 4.2E-83 T 29-03-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 CDC59_RS03590 8badedb5143dfa11b53d31f1c345a97a 426 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 332 353 - T 29-03-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CDC59_RS03590 8badedb5143dfa11b53d31f1c345a97a 426 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 17 415 9.1E-144 T 29-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CDC59_RS03590 8badedb5143dfa11b53d31f1c345a97a 426 SUPERFAMILY SSF53720 10 425 4.45E-115 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CDC59_RS03590 8badedb5143dfa11b53d31f1c345a97a 426 Gene3D G3DSA:3.40.605.10 246 426 4.9E-42 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CDC59_RS03590 8badedb5143dfa11b53d31f1c345a97a 426 Gene3D G3DSA:3.40.605.10 5 245 3.9E-46 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CDC59_RS03590 8badedb5143dfa11b53d31f1c345a97a 426 Pfam PF00171 Aldehyde dehydrogenase family 318 382 1.4E-7 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CDC59_RS03590 8badedb5143dfa11b53d31f1c345a97a 426 Pfam PF00171 Aldehyde dehydrogenase family 15 285 3.4E-16 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CDC59_RS03590 8badedb5143dfa11b53d31f1c345a97a 426 PIRSF PIRSF000151 2 426 4.8E-169 T 29-03-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 CDC59_RS03590 8badedb5143dfa11b53d31f1c345a97a 426 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 9 425 40.797 T 29-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CDC59_RS13355 6f9f63336cfcc2cb7075bbe37561097a 298 SUPERFAMILY SSF103481 185 286 9.94E-11 T 29-03-2018 CDC59_RS13355 6f9f63336cfcc2cb7075bbe37561097a 298 Pfam PF00892 EamA-like transporter family 7 143 2.3E-13 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CDC59_RS13355 6f9f63336cfcc2cb7075bbe37561097a 298 Pfam PF00892 EamA-like transporter family 152 282 1.5E-7 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CDC59_RS13355 6f9f63336cfcc2cb7075bbe37561097a 298 TIGRFAM TIGR00688 rarD: protein RarD 7 260 1.2E-69 T 29-03-2018 IPR004626 RarD protein GO:0005215|GO:0005887|GO:0006810 CDC59_RS13355 6f9f63336cfcc2cb7075bbe37561097a 298 SUPERFAMILY SSF103481 74 146 2.09E-12 T 29-03-2018 CDC59_RS08325 7434011fea40ae247be2ae68ebab15fd 519 SUPERFAMILY SSF52540 264 493 2.06E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS08325 7434011fea40ae247be2ae68ebab15fd 519 Gene3D G3DSA:3.40.50.300 21 249 1.7E-49 T 29-03-2018 CDC59_RS08325 7434011fea40ae247be2ae68ebab15fd 519 Pfam PF00005 ABC transporter 40 190 1.8E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS08325 7434011fea40ae247be2ae68ebab15fd 519 Pfam PF00005 ABC transporter 290 443 1.6E-20 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS08325 7434011fea40ae247be2ae68ebab15fd 519 SUPERFAMILY SSF52540 24 247 1.81E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS08325 7434011fea40ae247be2ae68ebab15fd 519 Gene3D G3DSA:3.40.50.300 275 496 4.3E-37 T 29-03-2018 CDC59_RS08325 7434011fea40ae247be2ae68ebab15fd 519 SMART SM00382 49 238 8.5E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS08325 7434011fea40ae247be2ae68ebab15fd 519 SMART SM00382 298 492 1.9E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS08325 7434011fea40ae247be2ae68ebab15fd 519 ProSitePatterns PS00211 ABC transporters family signature. 416 430 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS11190 5abe02db6e5a0acde506f8a23fa21287 522 PIRSF PIRSF002741 5 518 6.1E-102 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CDC59_RS11190 5abe02db6e5a0acde506f8a23fa21287 522 Gene3D G3DSA:3.40.190.10 174 286 2.2E-26 T 29-03-2018 CDC59_RS11190 5abe02db6e5a0acde506f8a23fa21287 522 SUPERFAMILY SSF53850 19 508 4.34E-126 T 29-03-2018 CDC59_RS11190 5abe02db6e5a0acde506f8a23fa21287 522 Gene3D G3DSA:3.10.105.10 287 493 7.1E-52 T 29-03-2018 CDC59_RS11190 5abe02db6e5a0acde506f8a23fa21287 522 Gene3D G3DSA:3.90.76.10 32 173 2.8E-31 T 29-03-2018 CDC59_RS11190 5abe02db6e5a0acde506f8a23fa21287 522 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 64 433 6.9E-91 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CDC59_RS19845 f472e3cc955db2b63103bc6d82f8cb3c 409 Pfam PF03600 Citrate transporter 66 342 2.9E-19 T 29-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 CDC59_RS11295 837b3735862a446f39df34b9930c1351 277 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 73 81 - T 29-03-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDC59_RS11295 837b3735862a446f39df34b9930c1351 277 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 182 192 - T 29-03-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDC59_RS11295 837b3735862a446f39df34b9930c1351 277 Gene3D G3DSA:3.40.50.1860 118 268 1.4E-39 T 29-03-2018 CDC59_RS11295 837b3735862a446f39df34b9930c1351 277 TIGRFAM TIGR00067 glut_race: glutamate racemase 9 248 1.2E-65 T 29-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDC59_RS11295 837b3735862a446f39df34b9930c1351 277 Pfam PF01177 Asp/Glu/Hydantoin racemase 9 216 6.1E-36 T 29-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDC59_RS11295 837b3735862a446f39df34b9930c1351 277 Hamap MF_00258 Glutamate racemase [murI]. 7 257 36.827 T 29-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDC59_RS11295 837b3735862a446f39df34b9930c1351 277 SUPERFAMILY SSF53681 112 256 2.29E-35 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDC59_RS11295 837b3735862a446f39df34b9930c1351 277 Gene3D G3DSA:3.40.50.1860 5 117 4.3E-27 T 29-03-2018 CDC59_RS11295 837b3735862a446f39df34b9930c1351 277 SUPERFAMILY SSF53681 8 109 1.73E-34 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDC59_RS14645 7d5de7ed986b7862d129243402eeeab3 398 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 290 380 1.2E-17 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CDC59_RS14645 7d5de7ed986b7862d129243402eeeab3 398 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 37 250 1.3E-73 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CDC59_RS14645 7d5de7ed986b7862d129243402eeeab3 398 SUPERFAMILY SSF69189 290 382 3.14E-21 T 29-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CDC59_RS14645 7d5de7ed986b7862d129243402eeeab3 398 SMART SM00936 290 380 1.5E-25 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CDC59_RS14645 7d5de7ed986b7862d129243402eeeab3 398 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 150 163 3.1E-18 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CDC59_RS14645 7d5de7ed986b7862d129243402eeeab3 398 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 123 140 3.1E-18 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CDC59_RS14645 7d5de7ed986b7862d129243402eeeab3 398 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 68 79 3.1E-18 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CDC59_RS14645 7d5de7ed986b7862d129243402eeeab3 398 Gene3D G3DSA:3.40.710.10 20 291 1.2E-46 T 29-03-2018 CDC59_RS14645 7d5de7ed986b7862d129243402eeeab3 398 Gene3D G3DSA:2.60.410.10 292 380 3.9E-17 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CDC59_RS14645 7d5de7ed986b7862d129243402eeeab3 398 SUPERFAMILY SSF56601 16 290 1.61E-77 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CDC59_RS14625 1f9900f7e65051e336bc22cd5701b5f9 665 PRINTS PR00344 Bacterial sensor protein C-terminal signature 605 615 6.3E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS14625 1f9900f7e65051e336bc22cd5701b5f9 665 PRINTS PR00344 Bacterial sensor protein C-terminal signature 587 601 6.3E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS14625 1f9900f7e65051e336bc22cd5701b5f9 665 PRINTS PR00344 Bacterial sensor protein C-terminal signature 618 636 6.3E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS14625 1f9900f7e65051e336bc22cd5701b5f9 665 PRINTS PR00344 Bacterial sensor protein C-terminal signature 642 655 6.3E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS14625 1f9900f7e65051e336bc22cd5701b5f9 665 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 543 654 1.6E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS14625 1f9900f7e65051e336bc22cd5701b5f9 665 SMART SM00387 542 658 3.6E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS14625 1f9900f7e65051e336bc22cd5701b5f9 665 Gene3D G3DSA:3.30.450.20 204 345 1.4E-5 T 29-03-2018 CDC59_RS14625 1f9900f7e65051e336bc22cd5701b5f9 665 SMART SM00388 432 500 4.1E-4 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS14625 1f9900f7e65051e336bc22cd5701b5f9 665 PIRSF PIRSF036431 28 665 2.7E-237 T 29-03-2018 IPR017055 Signal transduction histidine kinase, DctB (C4-dicarboxylate transport system regulator) CDC59_RS14625 1f9900f7e65051e336bc22cd5701b5f9 665 Gene3D G3DSA:1.10.287.130 420 491 2.8E-8 T 29-03-2018 CDC59_RS14625 1f9900f7e65051e336bc22cd5701b5f9 665 Gene3D G3DSA:3.30.450.20 95 203 8.1E-22 T 29-03-2018 CDC59_RS14625 1f9900f7e65051e336bc22cd5701b5f9 665 SUPERFAMILY SSF103190 90 218 7.06E-11 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CDC59_RS14625 1f9900f7e65051e336bc22cd5701b5f9 665 Pfam PF00512 His Kinase A (phospho-acceptor) domain 432 494 2.0E-7 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS14625 1f9900f7e65051e336bc22cd5701b5f9 665 Gene3D G3DSA:3.30.565.10 492 656 1.6E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS14625 1f9900f7e65051e336bc22cd5701b5f9 665 SUPERFAMILY SSF47384 422 495 1.1E-8 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS14625 1f9900f7e65051e336bc22cd5701b5f9 665 SUPERFAMILY SSF55874 488 654 2.49E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS14625 1f9900f7e65051e336bc22cd5701b5f9 665 Pfam PF02743 Cache domain 73 250 1.3E-19 T 29-03-2018 IPR033479 Double Cache domain 1 CDC59_RS07935 d1f1397b3df457d323bba86f67e41b4c 551 SUPERFAMILY SSF52540 287 538 3.48E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS07935 d1f1397b3df457d323bba86f67e41b4c 551 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 246 273 2.7E-5 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CDC59_RS07935 d1f1397b3df457d323bba86f67e41b4c 551 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 518 542 0.0024 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CDC59_RS07935 d1f1397b3df457d323bba86f67e41b4c 551 Pfam PF00005 ABC transporter 39 194 2.6E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS07935 d1f1397b3df457d323bba86f67e41b4c 551 Pfam PF00005 ABC transporter 315 467 3.6E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS07935 d1f1397b3df457d323bba86f67e41b4c 551 Gene3D G3DSA:3.40.50.300 282 546 1.1E-74 T 29-03-2018 CDC59_RS07935 d1f1397b3df457d323bba86f67e41b4c 551 Gene3D G3DSA:3.40.50.300 15 275 3.8E-67 T 29-03-2018 CDC59_RS07935 d1f1397b3df457d323bba86f67e41b4c 551 ProSitePatterns PS00211 ABC transporters family signature. 167 181 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS07935 d1f1397b3df457d323bba86f67e41b4c 551 ProSitePatterns PS00211 ABC transporters family signature. 439 453 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS07935 d1f1397b3df457d323bba86f67e41b4c 551 SMART SM00382 47 244 3.4E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS07935 d1f1397b3df457d323bba86f67e41b4c 551 SMART SM00382 323 516 5.6E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS07935 d1f1397b3df457d323bba86f67e41b4c 551 SUPERFAMILY SSF52540 17 265 1.11E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS06430 aa475e3f0140a89db4382e6e5c3c0453 238 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 2 236 2.4E-119 T 29-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 CDC59_RS06430 aa475e3f0140a89db4382e6e5c3c0453 238 SUPERFAMILY SSF55666 152 236 8.12E-27 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CDC59_RS06430 aa475e3f0140a89db4382e6e5c3c0453 238 Gene3D G3DSA:3.30.230.70 1 237 3.5E-58 T 29-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CDC59_RS06430 aa475e3f0140a89db4382e6e5c3c0453 238 Hamap MF_00564 Ribonuclease PH [rph]. 1 237 48.845 T 29-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 CDC59_RS06430 aa475e3f0140a89db4382e6e5c3c0453 238 Pfam PF01138 3' exoribonuclease family, domain 1 10 140 7.6E-19 T 29-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CDC59_RS06430 aa475e3f0140a89db4382e6e5c3c0453 238 Pfam PF03725 3' exoribonuclease family, domain 2 158 221 9.9E-11 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CDC59_RS06430 aa475e3f0140a89db4382e6e5c3c0453 238 SUPERFAMILY SSF54211 1 181 1.67E-43 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CDC59_RS06430 aa475e3f0140a89db4382e6e5c3c0453 238 ProSitePatterns PS01277 Ribonuclease PH signature. 116 128 - T 29-03-2018 IPR018336 Ribonuclease PH, conserved site CDC59_RS22690 86403dba53e41df5b3684b351e61ddc3 170 Pfam PF09351 Domain of unknown function (DUF1993) 6 166 2.4E-57 T 29-03-2018 IPR018531 Domain of unknown function DUF1993 CDC59_RS22690 86403dba53e41df5b3684b351e61ddc3 170 Gene3D G3DSA:1.20.120.450 3 170 1.2E-62 T 29-03-2018 CDC59_RS22690 86403dba53e41df5b3684b351e61ddc3 170 SUPERFAMILY SSF109854 5 167 1.05E-58 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CDC59_RS15300 65991c87264754ccf4d40d14d29e40f2 474 Pfam PF01040 UbiA prenyltransferase family 204 448 2.7E-20 T 29-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 CDC59_RS15300 65991c87264754ccf4d40d14d29e40f2 474 SUPERFAMILY SSF56784 59 159 8.68E-14 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS15300 65991c87264754ccf4d40d14d29e40f2 474 SUPERFAMILY SSF56784 4 18 8.68E-14 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS15300 65991c87264754ccf4d40d14d29e40f2 474 Gene3D G3DSA:3.40.50.1000 4 192 1.7E-9 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS15300 65991c87264754ccf4d40d14d29e40f2 474 Pfam PF12710 haloacid dehalogenase-like hydrolase 7 115 2.3E-7 T 29-03-2018 CDC59_RS10990 3e68f9edcc21c471b79067f62cd76e9a 275 Pfam PF16123 Hydroxyacylglutathione hydrolase C-terminus 187 274 8.9E-27 T 29-03-2018 IPR032282 Hydroxyacylglutathione hydrolase, C-terminal domain KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 CDC59_RS10990 3e68f9edcc21c471b79067f62cd76e9a 275 Gene3D G3DSA:3.60.15.10 4 274 7.1E-69 T 29-03-2018 IPR001279 Metallo-beta-lactamase CDC59_RS10990 3e68f9edcc21c471b79067f62cd76e9a 275 Hamap MF_01374 Hydroxyacylglutathione hydrolase [gloB]. 8 274 42.853 T 29-03-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 CDC59_RS10990 3e68f9edcc21c471b79067f62cd76e9a 275 Pfam PF00753 Metallo-beta-lactamase superfamily 21 186 1.8E-11 T 29-03-2018 IPR001279 Metallo-beta-lactamase CDC59_RS10990 3e68f9edcc21c471b79067f62cd76e9a 275 PIRSF PIRSF005457 5 274 8.2E-95 T 29-03-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 CDC59_RS10990 3e68f9edcc21c471b79067f62cd76e9a 275 TIGRFAM TIGR03413 GSH_gloB: hydroxyacylglutathione hydrolase 11 274 1.3E-95 T 29-03-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 CDC59_RS10990 3e68f9edcc21c471b79067f62cd76e9a 275 SUPERFAMILY SSF56281 10 274 3.5E-67 T 29-03-2018 IPR001279 Metallo-beta-lactamase CDC59_RS10990 3e68f9edcc21c471b79067f62cd76e9a 275 SMART SM00849 18 186 4.4E-26 T 29-03-2018 IPR001279 Metallo-beta-lactamase CDC59_RS00120 a3631aaddb1c938fb91cda55d9be3562 262 Gene3D G3DSA:3.20.20.150 1 260 9.6E-57 T 29-03-2018 CDC59_RS00120 a3631aaddb1c938fb91cda55d9be3562 262 PIRSF PIRSF006241 1 261 1.2E-97 T 29-03-2018 IPR026040 Hydroxypyruvate isomerase-like KEGG: 00630+5.3.1.22 CDC59_RS00120 a3631aaddb1c938fb91cda55d9be3562 262 SUPERFAMILY SSF51658 1 258 2.23E-82 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CDC59_RS00120 a3631aaddb1c938fb91cda55d9be3562 262 Pfam PF01261 Xylose isomerase-like TIM barrel 21 219 9.1E-32 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CDC59_RS18305 5e42e7f55e0c1a43632f714ece040e5d 225 SMART SM00100 16 134 1.8E-16 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CDC59_RS18305 5e42e7f55e0c1a43632f714ece040e5d 225 Pfam PF00027 Cyclic nucleotide-binding domain 36 120 6.7E-18 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CDC59_RS18305 5e42e7f55e0c1a43632f714ece040e5d 225 Gene3D G3DSA:2.60.120.10 5 150 3.9E-30 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CDC59_RS18305 5e42e7f55e0c1a43632f714ece040e5d 225 SUPERFAMILY SSF46785 151 220 8.08E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS18305 5e42e7f55e0c1a43632f714ece040e5d 225 Gene3D G3DSA:1.10.10.10 151 223 3.4E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS18305 5e42e7f55e0c1a43632f714ece040e5d 225 Pfam PF13545 Crp-like helix-turn-helix domain 154 220 1.5E-11 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CDC59_RS18305 5e42e7f55e0c1a43632f714ece040e5d 225 SMART SM00419 166 214 1.0E-6 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CDC59_RS18305 5e42e7f55e0c1a43632f714ece040e5d 225 SUPERFAMILY SSF51206 10 145 7.33E-33 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like CDC59_RS20520 c65e29452f72887d238261de03e88b0c 566 Pfam PF00589 Phage integrase family 379 550 2.7E-15 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CDC59_RS20520 c65e29452f72887d238261de03e88b0c 566 Gene3D G3DSA:1.10.443.10 350 566 1.2E-28 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CDC59_RS20520 c65e29452f72887d238261de03e88b0c 566 Gene3D G3DSA:1.10.150.20 115 179 8.5E-4 T 29-03-2018 CDC59_RS20520 c65e29452f72887d238261de03e88b0c 566 Pfam PF12482 Phage integrase protein 102 192 1.4E-30 T 29-03-2018 IPR022169 Protein of unknown function DUF3701 CDC59_RS20520 c65e29452f72887d238261de03e88b0c 566 Gene3D G3DSA:1.10.150.130 223 348 1.4E-17 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal CDC59_RS20520 c65e29452f72887d238261de03e88b0c 566 SUPERFAMILY SSF56349 225 558 1.85E-34 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CDC59_RS21670 350ece6753ae37cbbabcf052d97126aa 269 Gene3D G3DSA:2.40.50.100 123 185 5.9E-23 T 29-03-2018 CDC59_RS21670 350ece6753ae37cbbabcf052d97126aa 269 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 22 84 1.8E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS21670 350ece6753ae37cbbabcf052d97126aa 269 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 123 189 4.0E-21 T 29-03-2018 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 CDC59_RS21670 350ece6753ae37cbbabcf052d97126aa 269 SUPERFAMILY SSF46785 2 133 1.36E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS21670 350ece6753ae37cbbabcf052d97126aa 269 Gene3D G3DSA:1.10.10.10 2 113 9.9E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS21670 350ece6753ae37cbbabcf052d97126aa 269 TIGRFAM TIGR00637 ModE_repress: ModE molybdate transport repressor domain 19 110 2.1E-30 T 29-03-2018 IPR003725 Molybdenum-binding protein ModE, N-terminal CDC59_RS21670 350ece6753ae37cbbabcf052d97126aa 269 Pfam PF03459 TOBE domain 125 188 4.1E-18 T 29-03-2018 IPR005116 Transport-associated OB, type 1 CDC59_RS21670 350ece6753ae37cbbabcf052d97126aa 269 Pfam PF03459 TOBE domain 198 266 1.4E-10 T 29-03-2018 IPR005116 Transport-associated OB, type 1 CDC59_RS21670 350ece6753ae37cbbabcf052d97126aa 269 PIRSF PIRSF005763 1 269 8.0E-87 T 29-03-2018 IPR016462 Molybdate-dependent transcriptional regulator ModE GO:0006355|GO:0015689|GO:0030151 CDC59_RS21670 350ece6753ae37cbbabcf052d97126aa 269 SUPERFAMILY SSF50331 196 267 5.35E-13 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CDC59_RS21670 350ece6753ae37cbbabcf052d97126aa 269 SUPERFAMILY SSF50331 123 191 1.51E-20 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CDC59_RS21670 350ece6753ae37cbbabcf052d97126aa 269 Gene3D G3DSA:2.40.50.100 186 260 1.8E-15 T 29-03-2018 CDC59_RS10790 5cc42245b42c0edb336f6450ba0fb1ab 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 50 65 8.2E-13 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS10790 5cc42245b42c0edb336f6450ba0fb1ab 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 94 107 8.2E-13 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS10790 5cc42245b42c0edb336f6450ba0fb1ab 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 213 227 8.2E-13 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS10790 5cc42245b42c0edb336f6450ba0fb1ab 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 108 121 8.2E-13 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS10790 5cc42245b42c0edb336f6450ba0fb1ab 274 SUPERFAMILY SSF53474 4 265 1.16E-51 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS10790 5cc42245b42c0edb336f6450ba0fb1ab 274 Pfam PF12697 Alpha/beta hydrolase family 26 260 1.4E-18 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS10790 5cc42245b42c0edb336f6450ba0fb1ab 274 Gene3D G3DSA:3.40.50.1820 1 272 1.9E-44 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS18175 7a3fcc7b6ba9ff0bc1732fdd755d2490 569 Gene3D G3DSA:1.20.1540.10 203 392 1.3E-40 T 29-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CDC59_RS18175 7a3fcc7b6ba9ff0bc1732fdd755d2490 569 SUPERFAMILY SSF144091 203 394 1.7E-43 T 29-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CDC59_RS18175 7a3fcc7b6ba9ff0bc1732fdd755d2490 569 Pfam PF01694 Rhomboid family 248 391 8.9E-36 T 29-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CDC59_RS23170 349849b65f5e622cd953e6fbe67c9034 379 Gene3D G3DSA:3.10.310.10 6 182 7.8E-70 T 29-03-2018 CDC59_RS23170 349849b65f5e622cd953e6fbe67c9034 379 Gene3D G3DSA:3.10.310.10 183 353 2.3E-50 T 29-03-2018 CDC59_RS23170 349849b65f5e622cd953e6fbe67c9034 379 SUPERFAMILY SSF54506 9 175 6.8E-60 T 29-03-2018 CDC59_RS23170 349849b65f5e622cd953e6fbe67c9034 379 Pfam PF04303 PrpF protein 11 372 6.5E-106 T 29-03-2018 IPR007400 PrpF protein CDC59_RS23170 349849b65f5e622cd953e6fbe67c9034 379 SUPERFAMILY SSF54506 179 374 1.44E-53 T 29-03-2018 CDC59_RS20230 1f45f5f23c2040ee4f8ca203ccbb38bd 439 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 12 436 3.8E-165 T 29-03-2018 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CDC59_RS20230 1f45f5f23c2040ee4f8ca203ccbb38bd 439 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 26 91 2.2E-9 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CDC59_RS20230 1f45f5f23c2040ee4f8ca203ccbb38bd 439 SMART SM00382 160 342 1.7E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS20230 1f45f5f23c2040ee4f8ca203ccbb38bd 439 Gene3D G3DSA:3.40.50.300 93 364 1.0E-84 T 29-03-2018 CDC59_RS20230 1f45f5f23c2040ee4f8ca203ccbb38bd 439 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 148 357 2.2E-72 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CDC59_RS20230 1f45f5f23c2040ee4f8ca203ccbb38bd 439 SUPERFAMILY SSF52540 95 363 3.04E-95 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS20230 1f45f5f23c2040ee4f8ca203ccbb38bd 439 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 348 357 - T 29-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CDC59_RS20230 1f45f5f23c2040ee4f8ca203ccbb38bd 439 TIGRFAM TIGR02546 III_secr_ATP: type III secretion apparatus H+-transporting two-sector ATPase 20 436 3.8E-185 T 29-03-2018 IPR013380 ATPase, type III secretion system, H+-transporting GO:0005524|GO:0005737|GO:0006754|GO:0030254|GO:0030257|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CDC59_RS21465 d9cf51091914b9d6cf57d3e6fade1f42 451 Pfam PF00437 Type II/IV secretion system protein 94 369 4.3E-76 T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CDC59_RS21465 d9cf51091914b9d6cf57d3e6fade1f42 451 SUPERFAMILY SSF52540 73 402 9.27E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS21465 d9cf51091914b9d6cf57d3e6fade1f42 451 Gene3D G3DSA:3.30.450.90 87 191 2.2E-34 T 29-03-2018 CDC59_RS21465 d9cf51091914b9d6cf57d3e6fade1f42 451 Gene3D G3DSA:3.40.50.300 192 414 6.7E-14 T 29-03-2018 CDC59_RS06025 85eae827f659135a145bd0eaf1ff7011 378 Gene3D G3DSA:3.20.20.70 57 376 2.1E-50 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS06025 85eae827f659135a145bd0eaf1ff7011 378 SUPERFAMILY SSF51445 74 377 4.51E-41 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CDC59_RS06025 85eae827f659135a145bd0eaf1ff7011 378 Pfam PF03537 Glycoside-hydrolase family GH114 78 369 5.1E-33 T 29-03-2018 IPR004352 Glycoside-hydrolase family GH114, TIM-barrel domain CDC59_RS18120 b901c7b529658f27a48f413cf14c3f4a 1000 Gene3D G3DSA:2.40.180.10 25 339 3.4E-61 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CDC59_RS18120 b901c7b529658f27a48f413cf14c3f4a 1000 SUPERFAMILY SSF56634 27 336 1.44E-59 T 29-03-2018 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CDC59_RS18120 b901c7b529658f27a48f413cf14c3f4a 1000 Gene3D G3DSA:4.10.940.10 817 936 1.1E-16 T 29-03-2018 CDC59_RS23085 43b56d1d1d417674760062b2a8cc5990 233 Pfam PF03975 CheD chemotactic sensory transduction 94 197 4.4E-30 T 29-03-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 CDC59_RS23085 43b56d1d1d417674760062b2a8cc5990 233 Hamap MF_01440 Chemoreceptor glutamine deamidase CheD [cheD]. 47 201 28.654 T 29-03-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 CDC59_RS23085 43b56d1d1d417674760062b2a8cc5990 233 SUPERFAMILY SSF64438 52 200 5.68E-48 T 29-03-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic CDC59_RS08270 03659b6ce394b6552e1ec709a8957a53 357 SUPERFAMILY SSF51735 4 158 1.21E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS08270 03659b6ce394b6552e1ec709a8957a53 357 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 142 247 3.0E-7 T 29-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CDC59_RS08270 03659b6ce394b6552e1ec709a8957a53 357 SUPERFAMILY SSF55347 134 299 3.6E-29 T 29-03-2018 CDC59_RS08270 03659b6ce394b6552e1ec709a8957a53 357 Gene3D G3DSA:3.30.360.10 141 346 9.0E-41 T 29-03-2018 CDC59_RS08270 03659b6ce394b6552e1ec709a8957a53 357 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 8 127 2.2E-28 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CDC59_RS08270 03659b6ce394b6552e1ec709a8957a53 357 Gene3D G3DSA:3.40.50.720 1 140 2.7E-40 T 29-03-2018 CDC59_RS09895 38c0a252fc4af1b3d2780947413f0eca 326 Pfam PF02779 Transketolase, pyrimidine binding domain 5 178 1.1E-49 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CDC59_RS09895 38c0a252fc4af1b3d2780947413f0eca 326 Pfam PF02780 Transketolase, C-terminal domain 198 315 4.5E-36 T 29-03-2018 IPR033248 Transketolase, C-terminal domain CDC59_RS09895 38c0a252fc4af1b3d2780947413f0eca 326 SUPERFAMILY SSF52922 190 323 4.45E-39 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CDC59_RS09895 38c0a252fc4af1b3d2780947413f0eca 326 Gene3D G3DSA:3.40.50.970 1 195 1.1E-65 T 29-03-2018 CDC59_RS09895 38c0a252fc4af1b3d2780947413f0eca 326 SUPERFAMILY SSF52518 4 192 2.31E-68 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CDC59_RS09895 38c0a252fc4af1b3d2780947413f0eca 326 Gene3D G3DSA:3.40.50.920 196 324 1.5E-33 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CDC59_RS09895 38c0a252fc4af1b3d2780947413f0eca 326 SMART SM00861 4 179 3.0E-67 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CDC59_RS02750 6e951634755b749063c579193d8b96e6 325 SUPERFAMILY SSF81464 27 116 9.65E-23 T 29-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS02750 6e951634755b749063c579193d8b96e6 325 PIRSF PIRSF000292 1 307 1.8E-133 T 29-03-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 CDC59_RS02750 6e951634755b749063c579193d8b96e6 325 Gene3D G3DSA:2.60.40.420 113 278 6.7E-51 T 29-03-2018 IPR008972 Cupredoxin CDC59_RS02750 6e951634755b749063c579193d8b96e6 325 SUPERFAMILY SSF49503 118 279 3.96E-50 T 29-03-2018 IPR008972 Cupredoxin CDC59_RS02750 6e951634755b749063c579193d8b96e6 325 Gene3D G3DSA:1.10.287.90 27 112 3.4E-19 T 29-03-2018 CDC59_RS02750 6e951634755b749063c579193d8b96e6 325 TIGRFAM TIGR01433 CyoA: ubiquinol oxidase, subunit II 14 237 1.7E-115 T 29-03-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 CDC59_RS02750 6e951634755b749063c579193d8b96e6 325 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 147 218 1.1E-6 T 29-03-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS02750 6e951634755b749063c579193d8b96e6 325 Pfam PF06481 COX Aromatic Rich Motif 237 281 1.2E-17 T 29-03-2018 IPR010514 COX aromatic rich motif GO:0008827|GO:0016021|GO:0022900|GO:0055114 CDC59_RS15275 0d2e5d5f357772014aff7a3aca6e8b14 612 SUPERFAMILY SSF53697 250 612 8.91E-111 T 29-03-2018 CDC59_RS15275 0d2e5d5f357772014aff7a3aca6e8b14 612 Pfam PF13522 Glutamine amidotransferase domain 60 197 6.3E-22 T 29-03-2018 CDC59_RS15275 0d2e5d5f357772014aff7a3aca6e8b14 612 Gene3D G3DSA:3.40.50.10490 245 461 1.3E-61 T 29-03-2018 CDC59_RS15275 0d2e5d5f357772014aff7a3aca6e8b14 612 Pfam PF01380 SIS domain 465 594 3.1E-24 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CDC59_RS15275 0d2e5d5f357772014aff7a3aca6e8b14 612 Pfam PF01380 SIS domain 292 420 1.6E-28 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CDC59_RS15275 0d2e5d5f357772014aff7a3aca6e8b14 612 SUPERFAMILY SSF56235 2 241 5.58E-69 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CDC59_RS15275 0d2e5d5f357772014aff7a3aca6e8b14 612 Gene3D G3DSA:3.60.20.10 2 244 6.6E-62 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CDC59_RS15275 0d2e5d5f357772014aff7a3aca6e8b14 612 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 612 1.5E-247 T 29-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 CDC59_RS15275 0d2e5d5f357772014aff7a3aca6e8b14 612 Gene3D G3DSA:3.40.50.10490 462 610 4.3E-48 T 29-03-2018 CDC59_RS15275 0d2e5d5f357772014aff7a3aca6e8b14 612 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 612 38.977 T 29-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 CDC59_RS20780 7f02c020afa3d0fbfece34c7c63ef376 224 Gene3D G3DSA:1.20.144.10 7 159 1.3E-4 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CDC59_RS20780 7f02c020afa3d0fbfece34c7c63ef376 224 SUPERFAMILY SSF48317 7 152 2.62E-9 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CDC59_RS14265 e64f5c21eacc9c6f1e79d5a65ad987c8 217 Gene3D G3DSA:2.30.130.40 17 129 2.7E-28 T 29-03-2018 CDC59_RS14265 e64f5c21eacc9c6f1e79d5a65ad987c8 217 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 19 213 3.3E-24 T 29-03-2018 IPR003111 Lon, substrate-binding domain CDC59_RS14265 e64f5c21eacc9c6f1e79d5a65ad987c8 217 Gene3D G3DSA:1.10.4060.10 136 217 1.4E-10 T 29-03-2018 CDC59_RS14265 e64f5c21eacc9c6f1e79d5a65ad987c8 217 SUPERFAMILY SSF88697 19 212 3.73E-47 T 29-03-2018 IPR015947 PUA-like domain CDC59_RS14265 e64f5c21eacc9c6f1e79d5a65ad987c8 217 SMART SM00464 19 213 3.6E-8 T 29-03-2018 IPR003111 Lon, substrate-binding domain CDC59_RS23240 89f8c1f9a7efecaf61eb7da13011ec16 585 PIRSF PIRSF029745 1 585 1.9E-130 T 29-03-2018 IPR027282 Two partner secretion pathway transporter GO:0015031 CDC59_RS23240 89f8c1f9a7efecaf61eb7da13011ec16 585 Pfam PF03865 Haemolysin secretion/activation protein ShlB/FhaC/HecB 236 545 3.7E-73 T 29-03-2018 IPR005565 Haemolysin activator HlyB, C-terminal CDC59_RS23240 89f8c1f9a7efecaf61eb7da13011ec16 585 Pfam PF17287 POTRA domain 159 231 1.8E-15 T 29-03-2018 IPR035251 ShlB, POTRA domain CDC59_RS23240 89f8c1f9a7efecaf61eb7da13011ec16 585 Gene3D G3DSA:3.10.20.310 86 158 1.6E-13 T 29-03-2018 CDC59_RS23240 89f8c1f9a7efecaf61eb7da13011ec16 585 Pfam PF08479 POTRA domain, ShlB-type 83 158 1.8E-21 T 29-03-2018 IPR013686 Polypeptide-transport-associated, ShlB-type CDC59_RS23240 89f8c1f9a7efecaf61eb7da13011ec16 585 Gene3D G3DSA:2.40.160.50 204 584 8.3E-38 T 29-03-2018 CDC59_RS07150 d629c05934647f6bc0e2ce00f79de8d5 133 SUPERFAMILY SSF82649 2 126 9.42E-49 T 29-03-2018 CDC59_RS07150 d629c05934647f6bc0e2ce00f79de8d5 133 Pfam PF01592 NifU-like N terminal domain 3 126 2.9E-56 T 29-03-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 CDC59_RS07150 d629c05934647f6bc0e2ce00f79de8d5 133 TIGRFAM TIGR01999 iscU: FeS cluster assembly scaffold IscU 3 125 3.2E-69 T 29-03-2018 IPR011339 ISC system FeS cluster assembly, IscU scaffold GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 CDC59_RS07150 d629c05934647f6bc0e2ce00f79de8d5 133 Gene3D G3DSA:3.90.1010.10 1 133 5.9E-53 T 29-03-2018 CDC59_RS15225 6dd853654ca93f3e241e63387e9ae521 789 SUPERFAMILY SSF56935 124 788 3.83E-115 T 29-03-2018 CDC59_RS15225 6dd853654ca93f3e241e63387e9ae521 789 Pfam PF07715 TonB-dependent Receptor Plug Domain 154 251 5.6E-15 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CDC59_RS15225 6dd853654ca93f3e241e63387e9ae521 789 Pfam PF00593 TonB dependent receptor 357 787 7.1E-42 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CDC59_RS15225 6dd853654ca93f3e241e63387e9ae521 789 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 156 788 5.8E-96 T 29-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 CDC59_RS15225 6dd853654ca93f3e241e63387e9ae521 789 Gene3D G3DSA:2.40.170.20 264 788 6.9E-73 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CDC59_RS15225 6dd853654ca93f3e241e63387e9ae521 789 SMART SM00965 62 113 5.0E-8 T 29-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 CDC59_RS15225 6dd853654ca93f3e241e63387e9ae521 789 Gene3D G3DSA:2.170.130.10 120 263 6.8E-22 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CDC59_RS17535 afaba404397f53b0b13eae19a7d4828a 326 Gene3D G3DSA:3.20.20.100 1 325 1.1E-99 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CDC59_RS17535 afaba404397f53b0b13eae19a7d4828a 326 Pfam PF00248 Aldo/keto reductase family 16 305 2.4E-67 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CDC59_RS17535 afaba404397f53b0b13eae19a7d4828a 326 SUPERFAMILY SSF51430 1 311 4.98E-96 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CDC59_RS21165 46d3289c5156a5cd6f4406dfd443a3f5 175 Pfam PF01627 Hpt domain 71 134 9.8E-11 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CDC59_RS21165 46d3289c5156a5cd6f4406dfd443a3f5 175 Gene3D G3DSA:1.20.120.160 50 166 1.6E-15 T 29-03-2018 CDC59_RS21165 46d3289c5156a5cd6f4406dfd443a3f5 175 SUPERFAMILY SSF47226 42 136 9.55E-17 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CDC59_RS16130 abf74f1bb8f8940128a791da5d6edf9f 86 Gene3D G3DSA:3.40.630.30 1 84 2.4E-10 T 29-03-2018 CDC59_RS16130 abf74f1bb8f8940128a791da5d6edf9f 86 SUPERFAMILY SSF55729 2 84 7.57E-10 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDC59_RS16130 abf74f1bb8f8940128a791da5d6edf9f 86 Pfam PF13673 Acetyltransferase (GNAT) domain 1 85 4.0E-22 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CDC59_RS11800 55d97601860cb81c29f33ab414daafd3 200 Hamap MF_01357 NAD(P)H-quinone oxidoreductase subunit J, chloroplastic [ndhJ]. 8 168 35.07 T 29-03-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS11800 55d97601860cb81c29f33ab414daafd3 200 SUPERFAMILY SSF143243 8 181 2.22E-57 T 29-03-2018 CDC59_RS11800 55d97601860cb81c29f33ab414daafd3 200 ProSitePatterns PS00542 Respiratory chain NADH dehydrogenase 30 Kd subunit signature. 121 142 - T 29-03-2018 IPR020396 NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS11800 55d97601860cb81c29f33ab414daafd3 200 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 33 159 5.8E-41 T 29-03-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS11800 55d97601860cb81c29f33ab414daafd3 200 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 87 148 3.0E-29 T 29-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS11800 55d97601860cb81c29f33ab414daafd3 200 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 32 161 2.4E-44 T 29-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS05170 97a60ab200919a3e427150977f2d8d77 426 Pfam PF04233 Phage Mu protein F like protein 55 168 1.9E-14 T 29-03-2018 IPR006528 Phage head morphogenesis domain CDC59_RS19610 339ecffa04ada89dce7b8d02edad1632 995 TIGRFAM TIGR01646 vgr_GE: Rhs element Vgr protein 39 543 3.9E-78 T 29-03-2018 IPR006533 Type VI secretion system, RhsGE-associated Vgr protein CDC59_RS19610 339ecffa04ada89dce7b8d02edad1632 995 SUPERFAMILY SSF69279 28 212 1.25E-47 T 29-03-2018 CDC59_RS19610 339ecffa04ada89dce7b8d02edad1632 995 Pfam PF10106 Uncharacterized protein conserved in bacteria (DUF2345) 671 818 7.5E-41 T 29-03-2018 IPR018769 Domain of unknown function DUF2345, Vgr C-terminal CDC59_RS19610 339ecffa04ada89dce7b8d02edad1632 995 Pfam PF05954 Phage late control gene D protein (GPD) 46 357 1.6E-75 T 29-03-2018 CDC59_RS19610 339ecffa04ada89dce7b8d02edad1632 995 SUPERFAMILY SSF69255 395 489 3.4E-18 T 29-03-2018 CDC59_RS19610 339ecffa04ada89dce7b8d02edad1632 995 Gene3D G3DSA:2.40.50.230 401 491 4.0E-24 T 29-03-2018 IPR006531 Gp5 N-terminal CDC59_RS19610 339ecffa04ada89dce7b8d02edad1632 995 TIGRFAM TIGR03361 VI_Rhs_Vgr: type VI secretion system Vgr family protein 27 537 1.8E-90 T 29-03-2018 IPR017847 Type VI secretion system, RhsGE-associated Vgr family subset CDC59_RS19610 339ecffa04ada89dce7b8d02edad1632 995 Pfam PF13296 Putative type VI secretion system Rhs element Vgr 522 628 1.8E-31 T 29-03-2018 IPR028244 Putative type VI secretion system, Rhs element associated Vgr domain CDC59_RS19610 339ecffa04ada89dce7b8d02edad1632 995 SUPERFAMILY SSF69279 231 396 3.74E-19 T 29-03-2018 CDC59_RS19610 339ecffa04ada89dce7b8d02edad1632 995 Gene3D G3DSA:3.55.50.10 115 216 2.8E-25 T 29-03-2018 CDC59_RS15180 72c927525456134c9c7d8f76b917592b 280 Pfam PF10127 Predicted nucleotidyltransferase 26 270 8.6E-98 T 29-03-2018 IPR018775 Nucleotidyltransferase, predicted CDC59_RS15180 72c927525456134c9c7d8f76b917592b 280 Gene3D G3DSA:3.30.460.10 19 140 1.3E-4 T 29-03-2018 CDC59_RS08070 398230e08f4e211071fa1e1541d90459 402 Pfam PF02515 CoA-transferase family III 6 374 8.5E-130 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 CDC59_RS08070 398230e08f4e211071fa1e1541d90459 402 Gene3D G3DSA:3.40.50.10540 1 402 7.6E-142 T 29-03-2018 IPR023606 CoA-transferase family III domain CDC59_RS08070 398230e08f4e211071fa1e1541d90459 402 SUPERFAMILY SSF89796 4 397 2.35E-133 T 29-03-2018 IPR023606 CoA-transferase family III domain CDC59_RS04130 634e2bdc309fe45751372dbecb8b31b3 273 Gene3D G3DSA:3.20.20.60 1 271 1.4E-89 T 29-03-2018 CDC59_RS04130 634e2bdc309fe45751372dbecb8b31b3 273 PIRSF PIRSF000388 3 273 3.2E-100 T 29-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CDC59_RS04130 634e2bdc309fe45751372dbecb8b31b3 273 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 12 271 42.615 T 29-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CDC59_RS04130 634e2bdc309fe45751372dbecb8b31b3 273 SUPERFAMILY SSF51621 12 271 5.89E-106 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CDC59_RS04130 634e2bdc309fe45751372dbecb8b31b3 273 Pfam PF02548 Ketopantoate hydroxymethyltransferase 12 266 9.6E-110 T 29-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CDC59_RS04130 634e2bdc309fe45751372dbecb8b31b3 273 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 12 271 1.6E-98 T 29-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CDC59_RS07465 95b9c8276eefd51e985ad9d72310d8f0 450 Gene3D G3DSA:3.30.390.10 5 145 3.6E-33 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CDC59_RS07465 95b9c8276eefd51e985ad9d72310d8f0 450 Gene3D G3DSA:3.20.20.120 146 418 6.0E-52 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CDC59_RS07465 95b9c8276eefd51e985ad9d72310d8f0 450 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 50 142 3.7E-5 T 29-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CDC59_RS07465 95b9c8276eefd51e985ad9d72310d8f0 450 SUPERFAMILY SSF51604 144 419 4.34E-83 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CDC59_RS07465 95b9c8276eefd51e985ad9d72310d8f0 450 TIGRFAM TIGR03247 glucar-dehydr: glucarate dehydratase 11 450 2.2E-258 T 29-03-2018 IPR017653 Glucarate dehydratase GO:0000287|GO:0008872|GO:0019394 KEGG: 00053+4.2.1.40|MetaCyc: PWY-6499 CDC59_RS07465 95b9c8276eefd51e985ad9d72310d8f0 450 SMART SM00922 190 290 2.7E-18 T 29-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CDC59_RS07465 95b9c8276eefd51e985ad9d72310d8f0 450 SUPERFAMILY SSF54826 12 142 1.85E-34 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CDC59_RS07465 95b9c8276eefd51e985ad9d72310d8f0 450 Pfam PF13378 Enolase C-terminal domain-like 194 409 8.8E-36 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CDC59_RS03490 cf76d08f41a2612bba17179ddd2370a7 271 Gene3D G3DSA:3.20.20.70 1 271 2.4E-86 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS03490 cf76d08f41a2612bba17179ddd2370a7 271 Hamap MF_01215 Orotidine 5'-phosphate decarboxylase [pyrF]. 2 268 36.266 T 29-03-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDC59_RS03490 cf76d08f41a2612bba17179ddd2370a7 271 SMART SM00934 17 255 2.8E-52 T 29-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CDC59_RS03490 cf76d08f41a2612bba17179ddd2370a7 271 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 17 248 5.5E-34 T 29-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CDC59_RS03490 cf76d08f41a2612bba17179ddd2370a7 271 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 90 103 - T 29-03-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CDC59_RS03490 cf76d08f41a2612bba17179ddd2370a7 271 TIGRFAM TIGR02127 pyrF_sub2: orotidine 5'-phosphate decarboxylase 3 255 1.1E-76 T 29-03-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDC59_RS03490 cf76d08f41a2612bba17179ddd2370a7 271 SUPERFAMILY SSF51366 3 267 7.46E-80 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CDC59_RS10735 228624153389f54ad98320dd061f197a 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 2.4E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS10735 228624153389f54ad98320dd061f197a 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 2.4E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS10735 228624153389f54ad98320dd061f197a 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 2.4E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS10735 228624153389f54ad98320dd061f197a 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 2.4E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS10735 228624153389f54ad98320dd061f197a 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 2.4E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS10735 228624153389f54ad98320dd061f197a 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 2.4E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS10735 228624153389f54ad98320dd061f197a 259 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CDC59_RS10735 228624153389f54ad98320dd061f197a 259 Gene3D G3DSA:3.40.50.720 1 41 5.7E-8 T 29-03-2018 CDC59_RS10735 228624153389f54ad98320dd061f197a 259 Gene3D G3DSA:3.40.50.720 42 259 5.9E-57 T 29-03-2018 CDC59_RS10735 228624153389f54ad98320dd061f197a 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 256 2.2E-53 T 29-03-2018 CDC59_RS10735 228624153389f54ad98320dd061f197a 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 1.7E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS10735 228624153389f54ad98320dd061f197a 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 1.7E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS10735 228624153389f54ad98320dd061f197a 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 1.7E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS10735 228624153389f54ad98320dd061f197a 259 TIGRFAM TIGR01963 PHB_DH: 3-hydroxybutyrate dehydrogenase 5 259 2.2E-109 T 29-03-2018 IPR011294 3-hydroxybutyrate dehydrogenase GO:0003858|GO:0055114 CDC59_RS10735 228624153389f54ad98320dd061f197a 259 SUPERFAMILY SSF51735 3 258 1.46E-72 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS18465 b70d060da960e3477bf8a1d6563d2b8f 243 Pfam PF11828 Protein of unknown function (DUF3348) 2 241 1.7E-89 T 29-03-2018 IPR021783 Protein of unknown function DUF3348 CDC59_RS00865 776449611f9ee35e40117c0f092e93f4 380 Pfam PF11738 Protein of unknown function (DUF3298) 293 366 3.4E-9 T 29-03-2018 IPR021729 Domain of unknown function DUF3298 CDC59_RS00865 776449611f9ee35e40117c0f092e93f4 380 Gene3D G3DSA:3.90.640.20 290 377 3.9E-8 T 29-03-2018 IPR021729 Domain of unknown function DUF3298 CDC59_RS11950 c0dc205d7a341791f03a9658563b4255 134 ProSitePatterns PS01213 Protozoan/cyanobacterial globins signature. 60 84 - T 29-03-2018 IPR019795 Globin, bacterial-like, conserved site GO:0015671|GO:0019825 CDC59_RS11950 c0dc205d7a341791f03a9658563b4255 134 Gene3D G3DSA:1.10.490.10 7 134 3.7E-31 T 29-03-2018 CDC59_RS11950 c0dc205d7a341791f03a9658563b4255 134 Pfam PF01152 Bacterial-like globin 12 127 1.5E-47 T 29-03-2018 IPR001486 Truncated hemoglobin GO:0019825 CDC59_RS11950 c0dc205d7a341791f03a9658563b4255 134 SUPERFAMILY SSF46458 13 133 3.7E-36 T 29-03-2018 IPR009050 Globin-like CDC59_RS09300 1c2467abe59adf62c88b6980e85edb70 539 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 208 539 8.0E-140 T 29-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CDC59_RS09300 1c2467abe59adf62c88b6980e85edb70 539 SUPERFAMILY SSF52317 1 232 5.5E-56 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CDC59_RS09300 1c2467abe59adf62c88b6980e85edb70 539 Pfam PF00958 GMP synthase C terminal domain 453 538 7.9E-41 T 29-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CDC59_RS09300 1c2467abe59adf62c88b6980e85edb70 539 Pfam PF00117 Glutamine amidotransferase class-I 7 195 1.1E-33 T 29-03-2018 IPR017926 Glutamine amidotransferase CDC59_RS09300 1c2467abe59adf62c88b6980e85edb70 539 Gene3D G3DSA:3.40.50.620 217 395 9.0E-36 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDC59_RS09300 1c2467abe59adf62c88b6980e85edb70 539 Pfam PF02540 NAD synthase 209 249 5.6E-7 T 29-03-2018 IPR022310 NAD/GMP synthase CDC59_RS09300 1c2467abe59adf62c88b6980e85edb70 539 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 2 539 53.946 T 29-03-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 CDC59_RS09300 1c2467abe59adf62c88b6980e85edb70 539 Gene3D G3DSA:3.40.50.880 1 216 4.6E-47 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CDC59_RS09300 1c2467abe59adf62c88b6980e85edb70 539 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 5 199 4.4E-69 T 29-03-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CDC59_RS09300 1c2467abe59adf62c88b6980e85edb70 539 SUPERFAMILY SSF52402 192 414 6.62E-59 T 29-03-2018 CDC59_RS09300 1c2467abe59adf62c88b6980e85edb70 539 SUPERFAMILY SSF54810 400 539 6.67E-45 T 29-03-2018 CDC59_RS09300 1c2467abe59adf62c88b6980e85edb70 539 Gene3D G3DSA:3.30.300.10 396 539 1.8E-50 T 29-03-2018 CDC59_RS14315 07a93d53f5f12542768cddd3ec12ccdd 200 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 15 28 - T 29-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 CDC59_RS14315 07a93d53f5f12542768cddd3ec12ccdd 200 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 2 197 2.2E-60 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CDC59_RS14315 07a93d53f5f12542768cddd3ec12ccdd 200 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 2 190 36.498 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CDC59_RS14315 07a93d53f5f12542768cddd3ec12ccdd 200 SUPERFAMILY SSF53178 1 197 4.05E-66 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CDC59_RS14315 07a93d53f5f12542768cddd3ec12ccdd 200 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 109 119 - T 29-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 CDC59_RS14315 07a93d53f5f12542768cddd3ec12ccdd 200 Gene3D G3DSA:3.40.50.1470 1 200 9.1E-68 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CDC59_RS14315 07a93d53f5f12542768cddd3ec12ccdd 200 Pfam PF01195 Peptidyl-tRNA hydrolase 4 196 2.5E-55 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CDC59_RS10220 2d7be2134ac985ab71ae9387cd90709c 290 Gene3D G3DSA:1.10.600.10 15 290 6.0E-56 T 29-03-2018 IPR008949 Isoprenoid synthase domain CDC59_RS10220 2d7be2134ac985ab71ae9387cd90709c 290 TIGRFAM TIGR03465 HpnD: squalene synthase HpnD 23 288 3.2E-99 T 29-03-2018 IPR017828 Squalene/phytoene synthase HpnD GO:0016117|GO:0016767 CDC59_RS10220 2d7be2134ac985ab71ae9387cd90709c 290 Pfam PF00494 Squalene/phytoene synthase 28 277 2.3E-52 T 29-03-2018 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 CDC59_RS10220 2d7be2134ac985ab71ae9387cd90709c 290 SUPERFAMILY SSF48576 17 289 8.06E-60 T 29-03-2018 IPR008949 Isoprenoid synthase domain CDC59_RS17765 02414937459dd4c5db5427dc7c719540 947 Pfam PF00128 Alpha amylase, catalytic domain 37 103 1.4E-15 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CDC59_RS17765 02414937459dd4c5db5427dc7c719540 947 SUPERFAMILY SSF51445 259 508 1.46E-122 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CDC59_RS17765 02414937459dd4c5db5427dc7c719540 947 SUPERFAMILY SSF51445 10 188 1.46E-122 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CDC59_RS17765 02414937459dd4c5db5427dc7c719540 947 SUPERFAMILY SSF51445 539 840 1.46E-122 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CDC59_RS17765 02414937459dd4c5db5427dc7c719540 947 TIGRFAM TIGR02401 trehalose_TreY: malto-oligosyltrehalose synthase 11 941 1.4E-282 T 29-03-2018 IPR012767 Maltooligosyl trehalose synthase KEGG: 00500+5.4.99.15|MetaCyc: PWY-2661 CDC59_RS17765 02414937459dd4c5db5427dc7c719540 947 SMART SM00642 24 494 1.5E-6 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CDC59_RS17765 02414937459dd4c5db5427dc7c719540 947 Gene3D G3DSA:3.20.20.80 16 842 4.0E-102 T 29-03-2018 CDC59_RS18405 6cd8f9af4d5b0ccf3c2be3ffb7df2622 184 SUPERFAMILY SSF52218 5 176 1.86E-49 T 29-03-2018 IPR029039 Flavoprotein-like domain CDC59_RS18405 6cd8f9af4d5b0ccf3c2be3ffb7df2622 184 Pfam PF03358 NADPH-dependent FMN reductase 5 149 3.2E-34 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CDC59_RS18405 6cd8f9af4d5b0ccf3c2be3ffb7df2622 184 Gene3D G3DSA:3.40.50.360 2 184 1.2E-39 T 29-03-2018 IPR029039 Flavoprotein-like domain CDC59_RS08730 f494a95a482555a0461ec882ae07bb81 311 Gene3D G3DSA:3.10.25.10 205 309 1.4E-18 T 29-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CDC59_RS08730 f494a95a482555a0461ec882ae07bb81 311 Pfam PF00551 Formyl transferase 50 178 3.7E-25 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CDC59_RS08730 f494a95a482555a0461ec882ae07bb81 311 SUPERFAMILY SSF53328 5 204 7.98E-53 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CDC59_RS08730 f494a95a482555a0461ec882ae07bb81 311 Pfam PF02911 Formyl transferase, C-terminal domain 204 283 2.4E-13 T 29-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CDC59_RS08730 f494a95a482555a0461ec882ae07bb81 311 Gene3D G3DSA:3.40.50.170 2 201 1.9E-44 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CDC59_RS08730 f494a95a482555a0461ec882ae07bb81 311 SUPERFAMILY SSF50486 206 288 3.14E-18 T 29-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 CDC59_RS18280 4e4735e314acbcc5585a7a4406cdf4b5 240 SUPERFAMILY SSF46785 6 84 2.38E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS18280 4e4735e314acbcc5585a7a4406cdf4b5 240 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 72 1.4E-18 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDC59_RS18280 4e4735e314acbcc5585a7a4406cdf4b5 240 SMART SM00345 13 72 7.4E-18 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDC59_RS18280 4e4735e314acbcc5585a7a4406cdf4b5 240 Gene3D G3DSA:1.10.10.10 2 71 1.8E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS18280 4e4735e314acbcc5585a7a4406cdf4b5 240 SUPERFAMILY SSF64288 60 239 6.44E-42 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CDC59_RS18280 4e4735e314acbcc5585a7a4406cdf4b5 240 SMART SM00866 92 234 4.9E-32 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CDC59_RS18280 4e4735e314acbcc5585a7a4406cdf4b5 240 Pfam PF07702 UTRA domain 94 234 3.9E-35 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CDC59_RS18280 4e4735e314acbcc5585a7a4406cdf4b5 240 Gene3D G3DSA:3.40.1410.10 72 240 7.4E-30 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CDC59_RS21190 b74422219ad421e2a81c157f3201cc99 272 Gene3D G3DSA:3.10.20.10 37 123 5.7E-22 T 29-03-2018 CDC59_RS21190 b74422219ad421e2a81c157f3201cc99 272 Pfam PF02634 FdhD/NarQ family 36 271 6.5E-61 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CDC59_RS21190 b74422219ad421e2a81c157f3201cc99 272 PIRSF PIRSF015626 5 272 9.4E-78 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CDC59_RS21190 b74422219ad421e2a81c157f3201cc99 272 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 32 267 3.6E-56 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CDC59_RS21190 b74422219ad421e2a81c157f3201cc99 272 Hamap MF_00187 Sulfurtransferase FdhD [fdhD]. 11 272 28.84 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CDC59_RS21190 b74422219ad421e2a81c157f3201cc99 272 Gene3D G3DSA:3.40.140.10 142 272 4.2E-37 T 29-03-2018 CDC59_RS21190 b74422219ad421e2a81c157f3201cc99 272 SUPERFAMILY SSF53927 18 271 2.92E-67 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CDC59_RS12655 27b8c37d65a3bb662fa6ff9a0a9b8b1e 401 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 3 392 1.8E-126 T 29-03-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 CDC59_RS12655 27b8c37d65a3bb662fa6ff9a0a9b8b1e 401 SUPERFAMILY SSF52507 3 180 7.85E-60 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CDC59_RS12655 27b8c37d65a3bb662fa6ff9a0a9b8b1e 401 Gene3D G3DSA:3.40.50.1950 1 181 2.1E-59 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CDC59_RS12655 27b8c37d65a3bb662fa6ff9a0a9b8b1e 401 Pfam PF02441 Flavoprotein 6 176 1.8E-43 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CDC59_RS12655 27b8c37d65a3bb662fa6ff9a0a9b8b1e 401 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 185 367 1.5E-62 T 29-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CDC59_RS12655 27b8c37d65a3bb662fa6ff9a0a9b8b1e 401 SUPERFAMILY SSF102645 171 396 3.27E-70 T 29-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CDC59_RS12655 27b8c37d65a3bb662fa6ff9a0a9b8b1e 401 Gene3D G3DSA:3.40.50.10300 182 400 3.8E-61 T 29-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CDC59_RS06185 3a1ddceac5ad390249ed6d9f675cd7f4 315 Gene3D G3DSA:3.40.50.620 134 252 5.6E-32 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDC59_RS06185 3a1ddceac5ad390249ed6d9f675cd7f4 315 Hamap MF_01428 Glutamyl-Q tRNA(Asp) synthetase [gluQ]. 20 315 43.156 T 29-03-2018 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0006400|GO:0016876 CDC59_RS06185 3a1ddceac5ad390249ed6d9f675cd7f4 315 Gene3D G3DSA:3.40.50.620 20 133 1.0E-27 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDC59_RS06185 3a1ddceac5ad390249ed6d9f675cd7f4 315 TIGRFAM TIGR03838 queuosine_YadB: glutamyl-queuosine tRNA(Asp) synthetase 20 289 3.5E-116 T 29-03-2018 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0006400|GO:0016876 CDC59_RS06185 3a1ddceac5ad390249ed6d9f675cd7f4 315 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 21 269 4.1E-41 T 29-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 CDC59_RS06185 3a1ddceac5ad390249ed6d9f675cd7f4 315 PRINTS PR00987 Glutamyl-tRNA synthetase signature 52 65 6.7E-14 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CDC59_RS06185 3a1ddceac5ad390249ed6d9f675cd7f4 315 PRINTS PR00987 Glutamyl-tRNA synthetase signature 37 48 6.7E-14 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CDC59_RS06185 3a1ddceac5ad390249ed6d9f675cd7f4 315 PRINTS PR00987 Glutamyl-tRNA synthetase signature 200 210 6.7E-14 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CDC59_RS06185 3a1ddceac5ad390249ed6d9f675cd7f4 315 PRINTS PR00987 Glutamyl-tRNA synthetase signature 23 35 6.7E-14 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CDC59_RS06185 3a1ddceac5ad390249ed6d9f675cd7f4 315 PRINTS PR00987 Glutamyl-tRNA synthetase signature 216 224 6.7E-14 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CDC59_RS06185 3a1ddceac5ad390249ed6d9f675cd7f4 315 SUPERFAMILY SSF52374 20 288 1.37E-81 T 29-03-2018 CDC59_RS13675 489e324aeca6c6217b7fd2e3801d95f4 241 Gene3D G3DSA:3.90.550.10 1 239 2.8E-39 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDC59_RS13675 489e324aeca6c6217b7fd2e3801d95f4 241 Pfam PF00483 Nucleotidyl transferase 2 138 3.8E-22 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CDC59_RS13675 489e324aeca6c6217b7fd2e3801d95f4 241 SUPERFAMILY SSF53448 1 233 7.43E-53 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDC59_RS11790 4ea28e47d0bd7d11ffbf52067a8b42fd 167 TIGRFAM TIGR01958 nuoE_fam: NADH-quinone oxidoreductase, E subunit 9 157 1.3E-65 T 29-03-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS11790 4ea28e47d0bd7d11ffbf52067a8b42fd 167 ProSitePatterns PS01099 Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. 113 131 - T 29-03-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS11790 4ea28e47d0bd7d11ffbf52067a8b42fd 167 SUPERFAMILY SSF52833 3 159 3.47E-52 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS11790 4ea28e47d0bd7d11ffbf52067a8b42fd 167 Gene3D G3DSA:3.40.30.10 75 162 1.0E-11 T 29-03-2018 CDC59_RS11790 4ea28e47d0bd7d11ffbf52067a8b42fd 167 PIRSF PIRSF000216 1 167 1.1E-59 T 29-03-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS11790 4ea28e47d0bd7d11ffbf52067a8b42fd 167 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 11 156 6.1E-51 T 29-03-2018 CDC59_RS05890 af5c2012d99ea80b2be020e5379b60b5 1322 Gene3D G3DSA:1.25.40.10 449 601 4.7E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS05890 af5c2012d99ea80b2be020e5379b60b5 1322 Pfam PF13429 Tetratricopeptide repeat 533 810 5.9E-93 T 29-03-2018 CDC59_RS05890 af5c2012d99ea80b2be020e5379b60b5 1322 SUPERFAMILY SSF48452 53 90 1.06E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS05890 af5c2012d99ea80b2be020e5379b60b5 1322 SUPERFAMILY SSF48452 510 561 1.06E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS05890 af5c2012d99ea80b2be020e5379b60b5 1322 SUPERFAMILY SSF48452 384 420 1.06E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS05890 af5c2012d99ea80b2be020e5379b60b5 1322 Gene3D G3DSA:1.25.40.10 47 142 0.0023 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS05890 af5c2012d99ea80b2be020e5379b60b5 1322 Gene3D G3DSA:1.25.40.10 173 425 0.0015 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS05890 af5c2012d99ea80b2be020e5379b60b5 1322 Gene3D G3DSA:1.25.40.10 626 868 2.6E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS00790 881ed0000322eb44b242c0d6042ad10c 382 Gene3D G3DSA:3.40.50.2300 290 364 8.5E-5 T 29-03-2018 CDC59_RS00790 881ed0000322eb44b242c0d6042ad10c 382 Gene3D G3DSA:3.40.50.2300 25 149 9.5E-16 T 29-03-2018 CDC59_RS00790 881ed0000322eb44b242c0d6042ad10c 382 Pfam PF13458 Periplasmic binding protein 24 377 7.1E-56 T 29-03-2018 IPR028081 Leucine-binding protein domain CDC59_RS00790 881ed0000322eb44b242c0d6042ad10c 382 SUPERFAMILY SSF53822 25 380 1.2E-77 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CDC59_RS00790 881ed0000322eb44b242c0d6042ad10c 382 Gene3D G3DSA:3.40.50.2300 150 289 1.4E-28 T 29-03-2018 CDC59_RS12965 d04c33ad5815e3a87648784ae13995c5 510 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 280 495 1.2E-48 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CDC59_RS12965 d04c33ad5815e3a87648784ae13995c5 510 Pfam PF11741 AMIN domain 54 157 2.4E-23 T 29-03-2018 IPR021731 AMIN domain CDC59_RS12965 d04c33ad5815e3a87648784ae13995c5 510 Gene3D G3DSA:3.40.630.40 276 502 1.5E-55 T 29-03-2018 CDC59_RS12965 d04c33ad5815e3a87648784ae13995c5 510 SUPERFAMILY SSF53187 422 498 1.07E-53 T 29-03-2018 CDC59_RS12965 d04c33ad5815e3a87648784ae13995c5 510 SUPERFAMILY SSF53187 279 374 1.07E-53 T 29-03-2018 CDC59_RS12965 d04c33ad5815e3a87648784ae13995c5 510 SMART SM00646 340 495 6.1E-58 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CDC59_RS07075 051120118288d624044434fcd2ea0fdf 195 Gene3D G3DSA:3.40.109.10 8 195 3.3E-34 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CDC59_RS07075 051120118288d624044434fcd2ea0fdf 195 SUPERFAMILY SSF55469 10 192 1.03E-44 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CDC59_RS07075 051120118288d624044434fcd2ea0fdf 195 Hamap MF_01204 Probable malonic semialdehyde reductase RutE [rutE]. 1 195 46.896 T 29-03-2018 IPR023936 NADH dehydrogenase/NAD(P)H nitroreductase, putative, RutE GO:0016491|GO:0055114 CDC59_RS07075 051120118288d624044434fcd2ea0fdf 195 Pfam PF00881 Nitroreductase family 17 173 7.9E-14 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CDC59_RS00710 6c11394abfcfbe77e2b06c19198a76a5 246 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS00710 6c11394abfcfbe77e2b06c19198a76a5 246 SUPERFAMILY SSF52540 4 238 1.45E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS00710 6c11394abfcfbe77e2b06c19198a76a5 246 Gene3D G3DSA:3.40.50.300 2 238 7.3E-47 T 29-03-2018 CDC59_RS00710 6c11394abfcfbe77e2b06c19198a76a5 246 SMART SM00382 30 225 1.5E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS00710 6c11394abfcfbe77e2b06c19198a76a5 246 Pfam PF00005 ABC transporter 21 173 1.2E-21 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS07480 bccfaeb747ec9535c339d3931b7864a4 394 Pfam PF13609 Gram-negative porin 18 347 4.6E-39 T 29-03-2018 CDC59_RS07480 bccfaeb747ec9535c339d3931b7864a4 394 Gene3D G3DSA:2.40.160.10 17 394 2.7E-68 T 29-03-2018 CDC59_RS07480 bccfaeb747ec9535c339d3931b7864a4 394 SUPERFAMILY SSF56935 25 394 1.83E-80 T 29-03-2018 CDC59_RS07480 bccfaeb747ec9535c339d3931b7864a4 394 PRINTS PR00184 Neisseria sp. porin signature 322 346 9.6E-8 T 29-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 CDC59_RS07480 bccfaeb747ec9535c339d3931b7864a4 394 PRINTS PR00184 Neisseria sp. porin signature 165 182 9.6E-8 T 29-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 CDC59_RS07480 bccfaeb747ec9535c339d3931b7864a4 394 PRINTS PR00184 Neisseria sp. porin signature 63 88 9.6E-8 T 29-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 CDC59_RS13365 a9c431a9260c0357af6507e6c7bf293e 265 Pfam PF03591 AzlC protein 39 174 3.1E-31 T 29-03-2018 IPR011606 Branched-chain amino acid transport, permease CDC59_RS00825 6a84dd7b673481b0851f1543f6f95631 88 SUPERFAMILY SSF81333 8 82 1.96E-18 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CDC59_RS00825 6a84dd7b673481b0851f1543f6f95631 88 Hamap MF_01396 ATP synthase subunit c [atpH]. 13 78 13.765 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS00825 6a84dd7b673481b0851f1543f6f95631 88 ProSitePatterns PS00605 ATP synthase c subunit signature. 43 64 - T 29-03-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS00825 6a84dd7b673481b0851f1543f6f95631 88 Gene3D G3DSA:1.20.20.10 8 80 1.2E-15 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CDC59_RS00825 6a84dd7b673481b0851f1543f6f95631 88 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 24 80 1.8E-20 T 29-03-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CDC59_RS00825 6a84dd7b673481b0851f1543f6f95631 88 Pfam PF00137 ATP synthase subunit C 14 76 5.1E-10 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CDC59_RS09825 3db8d935c20b8f70ac648be9c69d43b9 128 Pfam PF07238 PilZ domain 25 110 8.5E-9 T 29-03-2018 IPR009875 PilZ domain GO:0035438 CDC59_RS09825 3db8d935c20b8f70ac648be9c69d43b9 128 Gene3D G3DSA:2.40.10.220 43 123 2.9E-4 T 29-03-2018 CDC59_RS23970 7814e76b834ec77e9977abf59a1915f2 434 PIRSF PIRSF005353 1 432 2.9E-174 T 29-03-2018 IPR026033 Purine permease PbuG-like CDC59_RS23970 7814e76b834ec77e9977abf59a1915f2 434 Pfam PF00860 Permease family 20 390 4.1E-56 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CDC59_RS11480 b752401d23df64e3521c10923b56dc8c 136 PIRSF PIRSF000178 1 133 1.1E-30 T 29-03-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CDC59_RS11480 b752401d23df64e3521c10923b56dc8c 136 SUPERFAMILY SSF81343 2 132 4.36E-28 T 29-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CDC59_RS11480 b752401d23df64e3521c10923b56dc8c 136 Gene3D G3DSA:1.20.1300.10 25 135 1.9E-22 T 29-03-2018 CDC59_RS11480 b752401d23df64e3521c10923b56dc8c 136 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 20 128 7.7E-25 T 29-03-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CDC59_RS11480 b752401d23df64e3521c10923b56dc8c 136 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 18 130 1.3E-34 T 29-03-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CDC59_RS14335 152f56d7772f45bdf90d225c49e402d4 215 Pfam PF03602 Conserved hypothetical protein 95 24 171 7.0E-41 T 29-03-2018 CDC59_RS14335 152f56d7772f45bdf90d225c49e402d4 215 Gene3D G3DSA:3.40.50.150 11 181 5.0E-32 T 29-03-2018 CDC59_RS14335 152f56d7772f45bdf90d225c49e402d4 215 SUPERFAMILY SSF53335 23 206 8.44E-42 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS14335 152f56d7772f45bdf90d225c49e402d4 215 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 137 143 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CDC59_RS14335 152f56d7772f45bdf90d225c49e402d4 215 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 20 171 8.0E-36 T 29-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 CDC59_RS01740 2a23ff817fe9534c019cefe9ead593a6 156 Pfam PF07963 Prokaryotic N-terminal methylation motif 17 42 8.9E-9 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS01740 2a23ff817fe9534c019cefe9ead593a6 156 Gene3D G3DSA:3.30.700.10 36 154 1.8E-33 T 29-03-2018 CDC59_RS01740 2a23ff817fe9534c019cefe9ead593a6 156 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 21 43 1.8E-8 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS01740 2a23ff817fe9534c019cefe9ead593a6 156 SUPERFAMILY SSF54523 49 155 4.03E-42 T 29-03-2018 CDC59_RS01740 2a23ff817fe9534c019cefe9ead593a6 156 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 21 41 - T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS01740 2a23ff817fe9534c019cefe9ead593a6 156 PRINTS PR00813 Bacterial general secretion pathway protein G signature 22 47 5.7E-18 T 29-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 CDC59_RS01740 2a23ff817fe9534c019cefe9ead593a6 156 PRINTS PR00813 Bacterial general secretion pathway protein G signature 58 76 5.7E-18 T 29-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 CDC59_RS01740 2a23ff817fe9534c019cefe9ead593a6 156 TIGRFAM TIGR01710 typeII_sec_gspG: type II secretion system protein G 21 155 1.9E-62 T 29-03-2018 IPR010054 General secretion pathway protein G GO:0008565|GO:0015627|GO:0015628 CDC59_RS01740 2a23ff817fe9534c019cefe9ead593a6 156 Pfam PF08334 Type II secretion system (T2SS), protein G 45 154 2.0E-45 T 29-03-2018 IPR013545 Type II secretion system protein G CDC59_RS22120 209681b1132d5e32b2bc589a20d43ddb 221 Gene3D G3DSA:3.50.30.40 4 174 1.3E-38 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CDC59_RS22120 209681b1132d5e32b2bc589a20d43ddb 221 SUPERFAMILY SSF89562 13 182 7.72E-31 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CDC59_RS22120 209681b1132d5e32b2bc589a20d43ddb 221 Pfam PF03737 Aldolase/RraA 18 171 6.9E-27 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CDC59_RS07875 afae42e0e5007e6f32a84fd12f297261 190 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 63 80 - T 29-03-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 CDC59_RS07875 afae42e0e5007e6f32a84fd12f297261 190 PIRSF PIRSF001467 15 188 3.5E-25 T 29-03-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 CDC59_RS07875 afae42e0e5007e6f32a84fd12f297261 190 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 42 57 8.9E-12 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CDC59_RS07875 afae42e0e5007e6f32a84fd12f297261 190 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 143 158 8.9E-12 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CDC59_RS07875 afae42e0e5007e6f32a84fd12f297261 190 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 68 80 8.9E-12 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CDC59_RS07875 afae42e0e5007e6f32a84fd12f297261 190 SUPERFAMILY SSF50891 25 187 2.92E-55 T 29-03-2018 IPR029000 Cyclophilin-like domain CDC59_RS07875 afae42e0e5007e6f32a84fd12f297261 190 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 29 185 1.2E-45 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CDC59_RS07875 afae42e0e5007e6f32a84fd12f297261 190 Gene3D G3DSA:2.40.100.10 15 190 1.2E-49 T 29-03-2018 IPR029000 Cyclophilin-like domain CDC59_RS23685 2c0704c8fb55319e99ccfd23dca94981 147 Pfam PF02560 Cyanate lyase C-terminal domain 80 145 3.1E-35 T 29-03-2018 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CDC59_RS23685 2c0704c8fb55319e99ccfd23dca94981 147 PRINTS PR01693 Cyanase signature 101 117 8.7E-27 T 29-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CDC59_RS23685 2c0704c8fb55319e99ccfd23dca94981 147 PRINTS PR01693 Cyanase signature 83 97 8.7E-27 T 29-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CDC59_RS23685 2c0704c8fb55319e99ccfd23dca94981 147 PRINTS PR01693 Cyanase signature 14 29 8.7E-27 T 29-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CDC59_RS23685 2c0704c8fb55319e99ccfd23dca94981 147 PRINTS PR01693 Cyanase signature 132 142 8.7E-27 T 29-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CDC59_RS23685 2c0704c8fb55319e99ccfd23dca94981 147 PRINTS PR01693 Cyanase signature 34 51 8.7E-27 T 29-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CDC59_RS23685 2c0704c8fb55319e99ccfd23dca94981 147 SUPERFAMILY SSF55234 80 147 3.4E-29 T 29-03-2018 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CDC59_RS23685 2c0704c8fb55319e99ccfd23dca94981 147 PIRSF PIRSF001263 1 147 5.8E-51 T 29-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CDC59_RS23685 2c0704c8fb55319e99ccfd23dca94981 147 SMART SM01116 75 147 1.9E-48 T 29-03-2018 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CDC59_RS23685 2c0704c8fb55319e99ccfd23dca94981 147 Hamap MF_00535 Cyanate hydratase [cynS]. 1 147 81.337 T 29-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CDC59_RS23685 2c0704c8fb55319e99ccfd23dca94981 147 SUPERFAMILY SSF47413 1 77 4.13E-20 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDC59_RS23685 2c0704c8fb55319e99ccfd23dca94981 147 TIGRFAM TIGR00673 cynS: cyanase 5 147 5.4E-52 T 29-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CDC59_RS23685 2c0704c8fb55319e99ccfd23dca94981 147 Gene3D G3DSA:3.30.1160.10 81 146 1.2E-36 T 29-03-2018 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CDC59_RS23685 2c0704c8fb55319e99ccfd23dca94981 147 Gene3D G3DSA:1.10.260.40 1 80 4.1E-7 T 29-03-2018 CDC59_RS12885 8b3b188c096764146627da3bf4d0236a 250 Gene3D G3DSA:3.40.50.720 20 240 4.9E-24 T 29-03-2018 CDC59_RS12885 8b3b188c096764146627da3bf4d0236a 250 SUPERFAMILY SSF51735 26 232 5.06E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS12885 8b3b188c096764146627da3bf4d0236a 250 Pfam PF13460 NAD(P)H-binding 31 183 9.3E-12 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS14835 32e89e88ba113fc355991de6ee15d8b0 130 Pfam PF00581 Rhodanese-like domain 17 105 4.2E-13 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS14835 32e89e88ba113fc355991de6ee15d8b0 130 SUPERFAMILY SSF52821 2 129 1.44E-22 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS14835 32e89e88ba113fc355991de6ee15d8b0 130 Gene3D G3DSA:3.40.250.10 1 130 2.4E-24 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS14835 32e89e88ba113fc355991de6ee15d8b0 130 SMART SM00450 5 113 1.2E-11 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS11860 7574ae0fce5c8b5911cf1fcb42111712 513 SUPERFAMILY SSF110921 392 501 4.45E-27 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CDC59_RS11860 7574ae0fce5c8b5911cf1fcb42111712 513 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 4 499 8.3E-214 T 29-03-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CDC59_RS11860 7574ae0fce5c8b5911cf1fcb42111712 513 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 199 212 - T 29-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CDC59_RS11860 7574ae0fce5c8b5911cf1fcb42111712 513 SMART SM00917 371 502 2.0E-39 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CDC59_RS11860 7574ae0fce5c8b5911cf1fcb42111712 513 Pfam PF08502 LeuA allosteric (dimerisation) domain 371 501 4.6E-35 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CDC59_RS11860 7574ae0fce5c8b5911cf1fcb42111712 513 Gene3D G3DSA:3.20.20.70 1 332 6.0E-108 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS11860 7574ae0fce5c8b5911cf1fcb42111712 513 SUPERFAMILY SSF51569 1 292 3.48E-96 T 29-03-2018 CDC59_RS11860 7574ae0fce5c8b5911cf1fcb42111712 513 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 12 28 - T 29-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CDC59_RS11860 7574ae0fce5c8b5911cf1fcb42111712 513 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 2 511 42.246 T 29-03-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CDC59_RS11860 7574ae0fce5c8b5911cf1fcb42111712 513 Pfam PF00682 HMGL-like 5 274 9.9E-99 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CDC59_RS17460 5a960f842931f2f9dfc82f62ed94fee5 326 Pfam PF03466 LysR substrate binding domain 112 316 2.5E-22 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS17460 5a960f842931f2f9dfc82f62ed94fee5 326 Gene3D G3DSA:1.10.10.10 6 101 3.2E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS17460 5a960f842931f2f9dfc82f62ed94fee5 326 SUPERFAMILY SSF46785 19 97 1.29E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS17460 5a960f842931f2f9dfc82f62ed94fee5 326 Gene3D G3DSA:3.40.190.10 112 202 1.3E-13 T 29-03-2018 CDC59_RS17460 5a960f842931f2f9dfc82f62ed94fee5 326 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 23 82 5.9E-15 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS17460 5a960f842931f2f9dfc82f62ed94fee5 326 Gene3D G3DSA:3.40.190.10 203 288 1.9E-16 T 29-03-2018 CDC59_RS17460 5a960f842931f2f9dfc82f62ed94fee5 326 SUPERFAMILY SSF53850 105 313 5.19E-44 T 29-03-2018 CDC59_RS20695 74a51fb9ec33dc38b0174a2ed5f59e38 393 SUPERFAMILY SSF56645 15 246 5.76E-47 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CDC59_RS20695 74a51fb9ec33dc38b0174a2ed5f59e38 393 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 15 124 6.8E-13 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CDC59_RS20695 74a51fb9ec33dc38b0174a2ed5f59e38 393 Gene3D G3DSA:1.20.140.10 229 393 9.4E-33 T 29-03-2018 CDC59_RS20695 74a51fb9ec33dc38b0174a2ed5f59e38 393 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 236 385 5.5E-29 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CDC59_RS20695 74a51fb9ec33dc38b0174a2ed5f59e38 393 Gene3D G3DSA:2.40.110.10 127 228 4.5E-26 T 29-03-2018 CDC59_RS20695 74a51fb9ec33dc38b0174a2ed5f59e38 393 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 128 224 5.0E-17 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CDC59_RS20695 74a51fb9ec33dc38b0174a2ed5f59e38 393 Gene3D G3DSA:1.10.540.10 9 126 8.2E-19 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CDC59_RS20695 74a51fb9ec33dc38b0174a2ed5f59e38 393 SUPERFAMILY SSF47203 235 388 3.87E-27 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CDC59_RS23735 24ca2d4bc54a20965d5da85326e018d6 234 Gene3D G3DSA:3.40.50.720 156 211 9.9E-11 T 29-03-2018 CDC59_RS23735 24ca2d4bc54a20965d5da85326e018d6 234 Gene3D G3DSA:3.40.50.720 2 155 1.5E-40 T 29-03-2018 CDC59_RS23735 24ca2d4bc54a20965d5da85326e018d6 234 SUPERFAMILY SSF51735 1 206 1.15E-54 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS23735 24ca2d4bc54a20965d5da85326e018d6 234 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 130 158 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CDC59_RS23735 24ca2d4bc54a20965d5da85326e018d6 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 181 6.5E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS23735 24ca2d4bc54a20965d5da85326e018d6 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 6.5E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS23735 24ca2d4bc54a20965d5da85326e018d6 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 69 80 6.5E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS23735 24ca2d4bc54a20965d5da85326e018d6 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 117 133 6.5E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS23735 24ca2d4bc54a20965d5da85326e018d6 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 162 6.5E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS23735 24ca2d4bc54a20965d5da85326e018d6 234 Pfam PF00106 short chain dehydrogenase 6 185 8.5E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS23735 24ca2d4bc54a20965d5da85326e018d6 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 69 80 1.4E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS23735 24ca2d4bc54a20965d5da85326e018d6 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 162 1.4E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS23735 24ca2d4bc54a20965d5da85326e018d6 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 123 131 1.4E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS05195 7ffc08046b7cc4aeb776e36e1642cb2c 165 Gene3D G3DSA:1.10.287.620 15 156 5.2E-4 T 29-03-2018 CDC59_RS17040 66331fb7862691754c4a2a74ace46de3 368 PRINTS PR01010 Flagellar P-ring protein signature 165 183 1.1E-77 T 29-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 CDC59_RS17040 66331fb7862691754c4a2a74ace46de3 368 PRINTS PR01010 Flagellar P-ring protein signature 60 75 1.1E-77 T 29-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 CDC59_RS17040 66331fb7862691754c4a2a74ace46de3 368 PRINTS PR01010 Flagellar P-ring protein signature 86 105 1.1E-77 T 29-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 CDC59_RS17040 66331fb7862691754c4a2a74ace46de3 368 PRINTS PR01010 Flagellar P-ring protein signature 191 209 1.1E-77 T 29-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 CDC59_RS17040 66331fb7862691754c4a2a74ace46de3 368 PRINTS PR01010 Flagellar P-ring protein signature 40 55 1.1E-77 T 29-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 CDC59_RS17040 66331fb7862691754c4a2a74ace46de3 368 PRINTS PR01010 Flagellar P-ring protein signature 255 267 1.1E-77 T 29-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 CDC59_RS17040 66331fb7862691754c4a2a74ace46de3 368 PRINTS PR01010 Flagellar P-ring protein signature 108 125 1.1E-77 T 29-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 CDC59_RS17040 66331fb7862691754c4a2a74ace46de3 368 PRINTS PR01010 Flagellar P-ring protein signature 125 143 1.1E-77 T 29-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 CDC59_RS17040 66331fb7862691754c4a2a74ace46de3 368 PRINTS PR01010 Flagellar P-ring protein signature 25 40 1.1E-77 T 29-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 CDC59_RS17040 66331fb7862691754c4a2a74ace46de3 368 Pfam PF02119 Flagellar P-ring protein 25 367 1.0E-135 T 29-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 CDC59_RS17040 66331fb7862691754c4a2a74ace46de3 368 Hamap MF_00416 Flagellar P-ring protein [flgI]. 5 368 37.122 T 29-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 CDC59_RS03260 0de49f2fae90697609421b0d34bfa5c4 372 SUPERFAMILY SSF88697 280 371 1.06E-23 T 29-03-2018 IPR015947 PUA-like domain CDC59_RS03260 0de49f2fae90697609421b0d34bfa5c4 372 PRINTS PR00474 Glutamate 5-kinase family signature 80 108 4.0E-49 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CDC59_RS03260 0de49f2fae90697609421b0d34bfa5c4 372 PRINTS PR00474 Glutamate 5-kinase family signature 213 233 4.0E-49 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CDC59_RS03260 0de49f2fae90697609421b0d34bfa5c4 372 PRINTS PR00474 Glutamate 5-kinase family signature 152 179 4.0E-49 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CDC59_RS03260 0de49f2fae90697609421b0d34bfa5c4 372 PRINTS PR00474 Glutamate 5-kinase family signature 46 60 4.0E-49 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CDC59_RS03260 0de49f2fae90697609421b0d34bfa5c4 372 PRINTS PR00474 Glutamate 5-kinase family signature 120 141 4.0E-49 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CDC59_RS03260 0de49f2fae90697609421b0d34bfa5c4 372 SMART SM00359 281 364 2.3E-18 T 29-03-2018 IPR002478 PUA domain GO:0003723 CDC59_RS03260 0de49f2fae90697609421b0d34bfa5c4 372 SUPERFAMILY SSF53633 9 259 3.4E-69 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CDC59_RS03260 0de49f2fae90697609421b0d34bfa5c4 372 Gene3D G3DSA:2.30.130.10 280 371 1.3E-29 T 29-03-2018 IPR002478 PUA domain GO:0003723 CDC59_RS03260 0de49f2fae90697609421b0d34bfa5c4 372 Pfam PF00696 Amino acid kinase family 10 238 1.9E-43 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CDC59_RS03260 0de49f2fae90697609421b0d34bfa5c4 372 Gene3D G3DSA:3.40.1160.10 2 269 1.9E-64 T 29-03-2018 CDC59_RS03260 0de49f2fae90697609421b0d34bfa5c4 372 Pfam PF01472 PUA domain 281 355 2.5E-23 T 29-03-2018 IPR002478 PUA domain GO:0003723 CDC59_RS03260 0de49f2fae90697609421b0d34bfa5c4 372 ProSitePatterns PS00902 Glutamate 5-kinase signature. 211 228 - T 29-03-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CDC59_RS03260 0de49f2fae90697609421b0d34bfa5c4 372 Hamap MF_00456 Glutamate 5-kinase [proB]. 9 264 37.276 T 29-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CDC59_RS03260 0de49f2fae90697609421b0d34bfa5c4 372 PIRSF PIRSF000729 4 372 2.4E-132 T 29-03-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 CDC59_RS03260 0de49f2fae90697609421b0d34bfa5c4 372 TIGRFAM TIGR01027 proB: glutamate 5-kinase 9 370 7.7E-131 T 29-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CDC59_RS17570 3e1d6ddafeade19087afc160d87806e9 195 SUPERFAMILY SSF48600 35 192 2.59E-39 T 29-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CDC59_RS17570 3e1d6ddafeade19087afc160d87806e9 195 Gene3D G3DSA:1.20.59.10 31 116 5.4E-17 T 29-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CDC59_RS17570 3e1d6ddafeade19087afc160d87806e9 195 TIGRFAM TIGR01806 CM_mono2: putative chorismate mutase 34 146 8.5E-30 T 29-03-2018 IPR008240 Chorismate mutase, periplasmic KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CDC59_RS17570 3e1d6ddafeade19087afc160d87806e9 195 Pfam PF01817 Chorismate mutase type II 40 108 3.1E-9 T 29-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CDC59_RS17570 3e1d6ddafeade19087afc160d87806e9 195 SMART SM00830 27 110 5.1E-15 T 29-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CDC59_RS17570 3e1d6ddafeade19087afc160d87806e9 195 PIRSF PIRSF026640 5 195 6.2E-48 T 29-03-2018 IPR008240 Chorismate mutase, periplasmic KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CDC59_RS03975 e5ea1332318feb0fe80206e63beeb479 109 SMART SM00530 14 69 9.4E-5 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDC59_RS03975 e5ea1332318feb0fe80206e63beeb479 109 SUPERFAMILY SSF47413 9 70 1.61E-11 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDC59_RS03975 e5ea1332318feb0fe80206e63beeb479 109 Pfam PF13560 Helix-turn-helix domain 10 66 1.7E-13 T 29-03-2018 CDC59_RS03975 e5ea1332318feb0fe80206e63beeb479 109 Gene3D G3DSA:1.10.260.40 2 108 2.2E-11 T 29-03-2018 CDC59_RS01755 c187a4d7dff132df2aefcf3b2da956e5 367 PIRSF PIRSF009283 1 362 7.8E-118 T 29-03-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 CDC59_RS01755 c187a4d7dff132df2aefcf3b2da956e5 367 Pfam PF14696 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal 6 153 1.3E-64 T 29-03-2018 CDC59_RS01755 c187a4d7dff132df2aefcf3b2da956e5 367 SUPERFAMILY SSF54593 1 348 5.96E-85 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CDC59_RS01755 c187a4d7dff132df2aefcf3b2da956e5 367 TIGRFAM TIGR01263 4HPPD: 4-hydroxyphenylpyruvate dioxygenase 14 361 7.4E-116 T 29-03-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 CDC59_RS01755 c187a4d7dff132df2aefcf3b2da956e5 367 Gene3D G3DSA:3.10.180.10 166 362 1.2E-59 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CDC59_RS01755 c187a4d7dff132df2aefcf3b2da956e5 367 Gene3D G3DSA:3.10.180.10 3 165 8.7E-19 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CDC59_RS01755 c187a4d7dff132df2aefcf3b2da956e5 367 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 171 282 1.2E-15 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CDC59_RS03070 17000bff30ac9c3cb05fe957093be1a5 439 Pfam PF07690 Major Facilitator Superfamily 287 429 4.2E-11 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDC59_RS03070 17000bff30ac9c3cb05fe957093be1a5 439 Pfam PF00083 Sugar (and other) transporter 28 237 1.7E-24 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CDC59_RS03070 17000bff30ac9c3cb05fe957093be1a5 439 ProSitePatterns PS00216 Sugar transport proteins signature 1. 307 323 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CDC59_RS03070 17000bff30ac9c3cb05fe957093be1a5 439 Gene3D G3DSA:1.20.1250.20 248 438 6.0E-22 T 29-03-2018 CDC59_RS03070 17000bff30ac9c3cb05fe957093be1a5 439 SUPERFAMILY SSF103473 18 436 4.45E-64 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS03070 17000bff30ac9c3cb05fe957093be1a5 439 Gene3D G3DSA:1.20.1250.20 20 240 3.4E-22 T 29-03-2018 CDC59_RS13610 545eb52616c8d5519c9aa4dd70436872 697 SUPERFAMILY SSF109604 350 498 2.25E-18 T 29-03-2018 CDC59_RS13610 545eb52616c8d5519c9aa4dd70436872 697 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 1 695 25.085 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CDC59_RS13610 545eb52616c8d5519c9aa4dd70436872 697 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 4 558 5.2E-195 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CDC59_RS13610 545eb52616c8d5519c9aa4dd70436872 697 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 326 342 2.5E-31 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CDC59_RS13610 545eb52616c8d5519c9aa4dd70436872 697 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 402 421 2.5E-31 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CDC59_RS13610 545eb52616c8d5519c9aa4dd70436872 697 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 5 18 2.5E-31 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CDC59_RS13610 545eb52616c8d5519c9aa4dd70436872 697 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 254 269 2.5E-31 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CDC59_RS13610 545eb52616c8d5519c9aa4dd70436872 697 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 50 62 2.5E-31 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CDC59_RS13610 545eb52616c8d5519c9aa4dd70436872 697 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 2 695 3.8E-205 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CDC59_RS13610 545eb52616c8d5519c9aa4dd70436872 697 Gene3D G3DSA:3.40.50.720 360 525 0.13 T 29-03-2018 CDC59_RS13610 545eb52616c8d5519c9aa4dd70436872 697 Gene3D G3DSA:1.10.730.10 583 692 5.0E-13 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDC59_RS13610 545eb52616c8d5519c9aa4dd70436872 697 Pfam PF05746 DALR anticodon binding domain 590 682 9.5E-8 T 29-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CDC59_RS03885 8a7544f23013b68f7b0abe92a999e4bd 162 SUPERFAMILY SSF54523 19 136 3.3E-13 T 29-03-2018 CDC59_RS03885 8a7544f23013b68f7b0abe92a999e4bd 162 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 16 36 - T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS03885 8a7544f23013b68f7b0abe92a999e4bd 162 Gene3D G3DSA:3.30.700.10 19 158 1.7E-14 T 29-03-2018 CDC59_RS03885 8a7544f23013b68f7b0abe92a999e4bd 162 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 15 38 7.1E-7 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS03885 8a7544f23013b68f7b0abe92a999e4bd 162 Pfam PF12019 Type II transport protein GspH 56 151 2.3E-11 T 29-03-2018 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 CDC59_RS03885 8a7544f23013b68f7b0abe92a999e4bd 162 Pfam PF07963 Prokaryotic N-terminal methylation motif 14 37 4.7E-6 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS04420 73c545be97bf09e1f2de8be8d047a800 522 Gene3D G3DSA:1.10.579.10 318 506 2.3E-72 T 29-03-2018 CDC59_RS04420 73c545be97bf09e1f2de8be8d047a800 522 Gene3D G3DSA:1.25.40.80 156 316 4.3E-37 T 29-03-2018 CDC59_RS04420 73c545be97bf09e1f2de8be8d047a800 522 Gene3D G3DSA:3.40.50.620 2 154 6.2E-32 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDC59_RS04420 73c545be97bf09e1f2de8be8d047a800 522 ProSitePatterns PS00691 DNA photolyases class 1 signature 2. 373 392 - T 29-03-2018 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal CDC59_RS04420 73c545be97bf09e1f2de8be8d047a800 522 Pfam PF00875 DNA photolyase 28 187 1.9E-43 T 29-03-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 CDC59_RS04420 73c545be97bf09e1f2de8be8d047a800 522 Pfam PF03441 FAD binding domain of DNA photolyase 300 502 8.1E-82 T 29-03-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 CDC59_RS04420 73c545be97bf09e1f2de8be8d047a800 522 PRINTS PR00147 DNA photolyase signature 353 369 1.3E-27 T 29-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 CDC59_RS04420 73c545be97bf09e1f2de8be8d047a800 522 PRINTS PR00147 DNA photolyase signature 412 426 1.3E-27 T 29-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 CDC59_RS04420 73c545be97bf09e1f2de8be8d047a800 522 PRINTS PR00147 DNA photolyase signature 167 183 1.3E-27 T 29-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 CDC59_RS04420 73c545be97bf09e1f2de8be8d047a800 522 PRINTS PR00147 DNA photolyase signature 373 391 1.3E-27 T 29-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 CDC59_RS04420 73c545be97bf09e1f2de8be8d047a800 522 SUPERFAMILY SSF48173 222 505 3.53E-100 T 29-03-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 CDC59_RS04420 73c545be97bf09e1f2de8be8d047a800 522 SUPERFAMILY SSF52425 26 204 1.96E-48 T 29-03-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 CDC59_RS10710 60146154c5aa2933cff5360481e576e6 635 Gene3D G3DSA:3.30.930.10 228 530 1.1E-118 T 29-03-2018 CDC59_RS10710 60146154c5aa2933cff5360481e576e6 635 SMART SM00863 169 218 1.0E-23 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CDC59_RS10710 60146154c5aa2933cff5360481e576e6 635 Gene3D G3DSA:3.30.980.10 69 227 5.8E-44 T 29-03-2018 CDC59_RS10710 60146154c5aa2933cff5360481e576e6 635 PRINTS PR01047 Threonyl-tRNA synthetase signature 361 384 7.0E-54 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CDC59_RS10710 60146154c5aa2933cff5360481e576e6 635 PRINTS PR01047 Threonyl-tRNA synthetase signature 506 519 7.0E-54 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CDC59_RS10710 60146154c5aa2933cff5360481e576e6 635 PRINTS PR01047 Threonyl-tRNA synthetase signature 463 491 7.0E-54 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CDC59_RS10710 60146154c5aa2933cff5360481e576e6 635 PRINTS PR01047 Threonyl-tRNA synthetase signature 533 545 7.0E-54 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CDC59_RS10710 60146154c5aa2933cff5360481e576e6 635 PRINTS PR01047 Threonyl-tRNA synthetase signature 328 356 7.0E-54 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CDC59_RS10710 60146154c5aa2933cff5360481e576e6 635 SUPERFAMILY SSF81271 2 61 8.5E-14 T 29-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CDC59_RS10710 60146154c5aa2933cff5360481e576e6 635 Gene3D G3DSA:3.10.20.30 1 64 2.2E-18 T 29-03-2018 IPR012675 Beta-grasp domain CDC59_RS10710 60146154c5aa2933cff5360481e576e6 635 Pfam PF03129 Anticodon binding domain 540 629 8.1E-21 T 29-03-2018 IPR004154 Anticodon-binding CDC59_RS10710 60146154c5aa2933cff5360481e576e6 635 Pfam PF02824 TGS domain 2 61 1.0E-7 T 29-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 CDC59_RS10710 60146154c5aa2933cff5360481e576e6 635 SUPERFAMILY SSF55681 242 525 2.3E-100 T 29-03-2018 CDC59_RS10710 60146154c5aa2933cff5360481e576e6 635 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 66 633 34.484 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CDC59_RS10710 60146154c5aa2933cff5360481e576e6 635 Gene3D G3DSA:3.40.50.800 531 635 1.0E-25 T 29-03-2018 IPR004154 Anticodon-binding CDC59_RS10710 60146154c5aa2933cff5360481e576e6 635 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 72 630 2.3E-221 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CDC59_RS10710 60146154c5aa2933cff5360481e576e6 635 SUPERFAMILY SSF55186 64 240 2.22E-67 T 29-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 CDC59_RS10710 60146154c5aa2933cff5360481e576e6 635 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 320 528 1.5E-43 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDC59_RS10710 60146154c5aa2933cff5360481e576e6 635 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 171 218 1.3E-14 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CDC59_RS10710 60146154c5aa2933cff5360481e576e6 635 SUPERFAMILY SSF52954 529 633 8.61E-31 T 29-03-2018 IPR004154 Anticodon-binding CDC59_RS00995 6c10c9686013716a1340a7167035ae0e 337 Pfam PF01757 Acyltransferase family 2 327 3.2E-36 T 29-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CDC59_RS11130 d7b8d5c3577b31cfd52190e936919554 267 Pfam PF15916 Domain of unknown function (DUF4743) 7 111 8.9E-28 T 29-03-2018 IPR031804 Domain of unknown function DUF4743 CDC59_RS11130 d7b8d5c3577b31cfd52190e936919554 267 Gene3D G3DSA:3.90.79.10 97 265 1.0E-20 T 29-03-2018 CDC59_RS11130 d7b8d5c3577b31cfd52190e936919554 267 Pfam PF00293 NUDIX domain 125 223 1.4E-7 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CDC59_RS11130 d7b8d5c3577b31cfd52190e936919554 267 SUPERFAMILY SSF55811 95 253 6.77E-22 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CDC59_RS19545 65b5a1410debe6bb26207f3b67f8b60c 159 Gene3D G3DSA:1.20.950.20 71 155 0.0023 T 29-03-2018 CDC59_RS03615 bd93e63eab008fc0b64c197f8f987d58 442 SUPERFAMILY SSF47384 215 283 5.1E-7 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS03615 bd93e63eab008fc0b64c197f8f987d58 442 SUPERFAMILY SSF55874 301 440 1.57E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS03615 bd93e63eab008fc0b64c197f8f987d58 442 SMART SM00387 330 442 1.1E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS03615 bd93e63eab008fc0b64c197f8f987d58 442 Pfam PF00512 His Kinase A (phospho-acceptor) domain 222 283 1.2E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS03615 bd93e63eab008fc0b64c197f8f987d58 442 Gene3D G3DSA:3.30.565.10 293 442 2.0E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS03615 bd93e63eab008fc0b64c197f8f987d58 442 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 330 440 2.2E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS03615 bd93e63eab008fc0b64c197f8f987d58 442 SMART SM00388 220 288 5.0E-5 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS03615 bd93e63eab008fc0b64c197f8f987d58 442 PRINTS PR00344 Bacterial sensor protein C-terminal signature 426 439 7.2E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS03615 bd93e63eab008fc0b64c197f8f987d58 442 PRINTS PR00344 Bacterial sensor protein C-terminal signature 389 399 7.2E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS03615 bd93e63eab008fc0b64c197f8f987d58 442 PRINTS PR00344 Bacterial sensor protein C-terminal signature 402 420 7.2E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS03615 bd93e63eab008fc0b64c197f8f987d58 442 PRINTS PR00344 Bacterial sensor protein C-terminal signature 371 385 7.2E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS03615 bd93e63eab008fc0b64c197f8f987d58 442 Gene3D G3DSA:1.10.287.130 187 283 2.2E-8 T 29-03-2018 CDC59_RS14885 d8b89186f26c0e67e863638243a5bccb 240 Pfam PF05036 Sporulation related domain 162 236 8.5E-18 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 CDC59_RS14885 d8b89186f26c0e67e863638243a5bccb 240 SUPERFAMILY SSF110997 162 237 1.09E-17 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 CDC59_RS14885 d8b89186f26c0e67e863638243a5bccb 240 Gene3D G3DSA:3.30.70.1070 158 237 3.0E-16 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 CDC59_RS04200 ac6870d221d9585bfaa0d29c7d8cfffc 171 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 90 169 1.5E-30 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CDC59_RS04200 ac6870d221d9585bfaa0d29c7d8cfffc 171 Gene3D G3DSA:3.30.160.70 3 86 2.6E-11 T 29-03-2018 CDC59_RS04200 ac6870d221d9585bfaa0d29c7d8cfffc 171 Gene3D G3DSA:1.10.10.10 87 171 9.8E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS04200 ac6870d221d9585bfaa0d29c7d8cfffc 171 SUPERFAMILY SSF53155 8 86 1.59E-16 T 29-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CDC59_RS04200 ac6870d221d9585bfaa0d29c7d8cfffc 171 SUPERFAMILY SSF46767 88 168 5.1E-29 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CDC59_RS04200 ac6870d221d9585bfaa0d29c7d8cfffc 171 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 89 168 1.3E-32 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CDC59_RS07090 cde2c0e19d7dd52bd4a21122a2ddb42c 239 SUPERFAMILY SSF48498 111 235 2.67E-35 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CDC59_RS07090 cde2c0e19d7dd52bd4a21122a2ddb42c 239 Gene3D G3DSA:1.10.357.10 93 237 9.4E-26 T 29-03-2018 CDC59_RS07090 cde2c0e19d7dd52bd4a21122a2ddb42c 239 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 57 1.4E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDC59_RS07090 cde2c0e19d7dd52bd4a21122a2ddb42c 239 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 65 88 1.4E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDC59_RS07090 cde2c0e19d7dd52bd4a21122a2ddb42c 239 Pfam PF00440 Bacterial regulatory proteins, tetR family 44 90 7.9E-14 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDC59_RS07090 cde2c0e19d7dd52bd4a21122a2ddb42c 239 Gene3D G3DSA:1.10.10.60 12 92 3.4E-20 T 29-03-2018 CDC59_RS07090 cde2c0e19d7dd52bd4a21122a2ddb42c 239 SUPERFAMILY SSF46689 31 114 1.44E-19 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS08150 67ba382e50f0d45706a2f31c156cbe48 265 Gene3D G3DSA:1.25.40.10 200 254 0.011 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS08150 67ba382e50f0d45706a2f31c156cbe48 265 Pfam PF13181 Tetratricopeptide repeat 82 113 9.5E-5 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CDC59_RS08150 67ba382e50f0d45706a2f31c156cbe48 265 Pfam PF13181 Tetratricopeptide repeat 152 184 0.0034 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CDC59_RS08150 67ba382e50f0d45706a2f31c156cbe48 265 TIGRFAM TIGR02521 type_IV_pilW: type IV pilus biogenesis/stability protein PilW 9 250 3.2E-81 T 29-03-2018 IPR013360 Pilus biogenesis/stability type IV, PilW CDC59_RS08150 67ba382e50f0d45706a2f31c156cbe48 265 Gene3D G3DSA:1.25.40.10 25 163 4.3E-22 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS08150 67ba382e50f0d45706a2f31c156cbe48 265 SUPERFAMILY SSF48452 49 211 2.31E-19 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS08150 67ba382e50f0d45706a2f31c156cbe48 265 SMART SM00028 80 113 0.012 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CDC59_RS08150 67ba382e50f0d45706a2f31c156cbe48 265 SMART SM00028 151 184 4.2E-4 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CDC59_RS08150 67ba382e50f0d45706a2f31c156cbe48 265 SMART SM00028 46 79 17.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CDC59_RS08150 67ba382e50f0d45706a2f31c156cbe48 265 Gene3D G3DSA:1.25.40.10 164 199 1.6E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS11425 630034efec18a69dd7b550ae65042d9e 274 Gene3D G3DSA:3.30.70.660 106 247 9.5E-39 T 29-03-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDC59_RS11425 630034efec18a69dd7b550ae65042d9e 274 SUPERFAMILY SSF55120 1 255 3.74E-88 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDC59_RS11425 630034efec18a69dd7b550ae65042d9e 274 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 3 243 2.2E-65 T 29-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDC59_RS11425 630034efec18a69dd7b550ae65042d9e 274 Pfam PF01416 tRNA pseudouridine synthase 9 103 4.8E-10 T 29-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDC59_RS11425 630034efec18a69dd7b550ae65042d9e 274 Pfam PF01416 tRNA pseudouridine synthase 147 249 2.2E-32 T 29-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDC59_RS11425 630034efec18a69dd7b550ae65042d9e 274 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 2 248 35.098 T 29-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDC59_RS11425 630034efec18a69dd7b550ae65042d9e 274 Gene3D G3DSA:3.30.70.580 1 105 4.1E-33 T 29-03-2018 CDC59_RS11425 630034efec18a69dd7b550ae65042d9e 274 PIRSF PIRSF001430 1 260 2.3E-74 T 29-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDC59_RS19995 c6663abbd174ba1cdd544d7706a13951 91 SUPERFAMILY SSF143011 2 88 1.8E-6 T 29-03-2018 IPR035095 Toxin RelE-like domain CDC59_RS19995 c6663abbd174ba1cdd544d7706a13951 91 Gene3D G3DSA:3.30.2310.20 1 90 1.4E-6 T 29-03-2018 CDC59_RS19995 c6663abbd174ba1cdd544d7706a13951 91 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 3 90 2.7E-15 T 29-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family CDC59_RS17880 7666bdfd59b0a4112da8161175c14ac4 529 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 340 496 5.8E-48 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CDC59_RS17880 7666bdfd59b0a4112da8161175c14ac4 529 SMART SM00091 8 74 2.3E-4 T 29-03-2018 IPR000014 PAS domain CDC59_RS17880 7666bdfd59b0a4112da8161175c14ac4 529 SUPERFAMILY SSF55785 18 114 2.79E-27 T 29-03-2018 IPR000014 PAS domain CDC59_RS17880 7666bdfd59b0a4112da8161175c14ac4 529 SUPERFAMILY SSF58104 248 528 8.63E-68 T 29-03-2018 CDC59_RS17880 7666bdfd59b0a4112da8161175c14ac4 529 Pfam PF08447 PAS fold 30 110 9.2E-15 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 CDC59_RS17880 7666bdfd59b0a4112da8161175c14ac4 529 Pfam PF00672 HAMP domain 228 275 2.2E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CDC59_RS17880 7666bdfd59b0a4112da8161175c14ac4 529 SMART SM00283 281 528 5.1E-80 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CDC59_RS17880 7666bdfd59b0a4112da8161175c14ac4 529 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 456 485 5.3E-49 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS17880 7666bdfd59b0a4112da8161175c14ac4 529 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 379 406 5.3E-49 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS17880 7666bdfd59b0a4112da8161175c14ac4 529 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 408 437 5.3E-49 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS17880 7666bdfd59b0a4112da8161175c14ac4 529 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 302 331 5.3E-49 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS17880 7666bdfd59b0a4112da8161175c14ac4 529 Gene3D G3DSA:3.40.50.10600 8 126 2.3E-26 T 29-03-2018 CDC59_RS17880 7666bdfd59b0a4112da8161175c14ac4 529 SMART SM00304 228 280 3.2E-11 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CDC59_RS17880 7666bdfd59b0a4112da8161175c14ac4 529 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 21 113 8.8E-14 T 29-03-2018 IPR000014 PAS domain CDC59_RS17880 7666bdfd59b0a4112da8161175c14ac4 529 Gene3D G3DSA:1.10.287.950 226 334 6.7E-16 T 29-03-2018 CDC59_RS17880 7666bdfd59b0a4112da8161175c14ac4 529 Gene3D G3DSA:1.10.287.950 335 529 3.4E-45 T 29-03-2018 CDC59_RS06725 cad67eded2967f25164b93742b6f2ee3 213 Pfam PF05239 PRC-barrel domain 141 208 2.9E-8 T 29-03-2018 IPR027275 PRC-barrel domain CDC59_RS06725 cad67eded2967f25164b93742b6f2ee3 213 Gene3D G3DSA:2.40.30.60 43 137 5.3E-21 T 29-03-2018 IPR002676 RimM protein GO:0006364 CDC59_RS06725 cad67eded2967f25164b93742b6f2ee3 213 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 45 210 2.4E-39 T 29-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 CDC59_RS06725 cad67eded2967f25164b93742b6f2ee3 213 Pfam PF01782 RimM N-terminal domain 46 134 3.0E-18 T 29-03-2018 IPR002676 RimM protein GO:0006364 CDC59_RS06725 cad67eded2967f25164b93742b6f2ee3 213 SUPERFAMILY SSF50447 43 136 1.02E-14 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CDC59_RS06725 cad67eded2967f25164b93742b6f2ee3 213 SUPERFAMILY SSF50346 143 210 3.77E-18 T 29-03-2018 IPR011033 PRC-barrel-like CDC59_RS06725 cad67eded2967f25164b93742b6f2ee3 213 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 44 213 21.975 T 29-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 CDC59_RS06725 cad67eded2967f25164b93742b6f2ee3 213 Gene3D G3DSA:2.30.30.240 139 208 9.8E-24 T 29-03-2018 CDC59_RS19085 fdf289db7c064078aade7616a299e9f0 254 Pfam PF11760 Cobalamin synthesis G N-terminal 42 122 8.6E-30 T 29-03-2018 IPR021744 Cobalamin synthesis G, N-terminal KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 CDC59_RS19085 fdf289db7c064078aade7616a299e9f0 254 Gene3D G3DSA:3.30.420.180 117 247 1.0E-36 T 29-03-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 CDC59_RS19085 fdf289db7c064078aade7616a299e9f0 254 SUPERFAMILY SSF159672 2 121 2.75E-40 T 29-03-2018 CDC59_RS19085 fdf289db7c064078aade7616a299e9f0 254 SUPERFAMILY SSF159672 157 237 2.75E-40 T 29-03-2018 CDC59_RS19085 fdf289db7c064078aade7616a299e9f0 254 Pfam PF01890 Cobalamin synthesis G C-terminus 127 242 5.5E-33 T 29-03-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 CDC59_RS19900 9aa6a3e6fe7672eea2d416c2cbdb26ec 288 Hamap MF_01375 Phosphonoacetaldehyde hydrolase [phnX]. 1 288 130.82 T 29-03-2018 IPR006323 Phosphonoacetaldehyde hydrolase GO:0019700|GO:0050194 KEGG: 00440+3.11.1.1 CDC59_RS19900 9aa6a3e6fe7672eea2d416c2cbdb26ec 288 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 97 219 1.2E-10 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDC59_RS19900 9aa6a3e6fe7672eea2d416c2cbdb26ec 288 Gene3D G3DSA:1.10.150.240 40 112 6.0E-31 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CDC59_RS19900 9aa6a3e6fe7672eea2d416c2cbdb26ec 288 Pfam PF00702 haloacid dehalogenase-like hydrolase 108 214 4.2E-7 T 29-03-2018 CDC59_RS19900 9aa6a3e6fe7672eea2d416c2cbdb26ec 288 SUPERFAMILY SSF56784 23 275 3.74E-54 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS19900 9aa6a3e6fe7672eea2d416c2cbdb26ec 288 TIGRFAM TIGR01422 phosphonatase: phosphonoacetaldehyde hydrolase 22 273 3.8E-105 T 29-03-2018 IPR006323 Phosphonoacetaldehyde hydrolase GO:0019700|GO:0050194 KEGG: 00440+3.11.1.1 CDC59_RS19900 9aa6a3e6fe7672eea2d416c2cbdb26ec 288 Gene3D G3DSA:3.40.50.1000 113 280 1.1E-22 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS10085 56738945b6fc56af386ddeef2b7e07af 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 9.3E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS10085 56738945b6fc56af386ddeef2b7e07af 306 SUPERFAMILY SSF53850 91 299 4.52E-44 T 29-03-2018 CDC59_RS10085 56738945b6fc56af386ddeef2b7e07af 306 Gene3D G3DSA:1.10.10.10 2 84 3.4E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS10085 56738945b6fc56af386ddeef2b7e07af 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 2.4E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS10085 56738945b6fc56af386ddeef2b7e07af 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 2.4E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS10085 56738945b6fc56af386ddeef2b7e07af 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 2.4E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS10085 56738945b6fc56af386ddeef2b7e07af 306 Gene3D G3DSA:3.40.190.10 90 178 2.0E-15 T 29-03-2018 CDC59_RS10085 56738945b6fc56af386ddeef2b7e07af 306 SUPERFAMILY SSF46785 5 86 2.93E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS10085 56738945b6fc56af386ddeef2b7e07af 306 Gene3D G3DSA:3.40.190.10 179 266 1.7E-22 T 29-03-2018 CDC59_RS10085 56738945b6fc56af386ddeef2b7e07af 306 Pfam PF03466 LysR substrate binding domain 89 295 2.1E-41 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS09045 678c0d877cd0efada15b2664bef41ccb 116 SUPERFAMILY SSF57625 70 109 1.26E-5 T 29-03-2018 IPR002557 Chitin binding domain GO:0005576|GO:0006030|GO:0008061 Reactome: R-HSA-71387 CDC59_RS09045 678c0d877cd0efada15b2664bef41ccb 116 SMART SM00494 47 113 0.0093 T 29-03-2018 IPR002557 Chitin binding domain GO:0005576|GO:0006030|GO:0008061 Reactome: R-HSA-71387 CDC59_RS09045 678c0d877cd0efada15b2664bef41ccb 116 Gene3D G3DSA:2.170.140.10 38 114 4.9E-6 T 29-03-2018 IPR002557 Chitin binding domain GO:0005576|GO:0006030|GO:0008061 Reactome: R-HSA-71387 CDC59_RS09045 678c0d877cd0efada15b2664bef41ccb 116 Pfam PF01607 Chitin binding Peritrophin-A domain 71 110 1.0E-4 T 29-03-2018 IPR002557 Chitin binding domain GO:0005576|GO:0006030|GO:0008061 Reactome: R-HSA-71387 CDC59_RS15975 7e1f1c0bd7b156eace54421f8b72bd5f 335 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 65 220 4.7E-21 T 29-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 CDC59_RS15975 7e1f1c0bd7b156eace54421f8b72bd5f 335 SUPERFAMILY SSF109709 155 269 1.96E-15 T 29-03-2018 CDC59_RS15975 7e1f1c0bd7b156eace54421f8b72bd5f 335 Pfam PF02195 ParB-like nuclease domain 69 152 3.1E-12 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CDC59_RS15975 7e1f1c0bd7b156eace54421f8b72bd5f 335 Gene3D G3DSA:1.10.10.730 162 210 8.8E-5 T 29-03-2018 CDC59_RS15975 7e1f1c0bd7b156eace54421f8b72bd5f 335 SUPERFAMILY SSF110849 68 163 1.46E-17 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CDC59_RS15975 7e1f1c0bd7b156eace54421f8b72bd5f 335 SMART SM00470 68 161 4.8E-9 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CDC59_RS15975 7e1f1c0bd7b156eace54421f8b72bd5f 335 Gene3D G3DSA:3.90.1530.10 55 161 2.2E-18 T 29-03-2018 CDC59_RS15955 fd2c8eaf2e3be2fc86240f8833fae3b4 517 SUPERFAMILY SSF48295 413 516 2.04E-37 T 29-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 CDC59_RS15955 fd2c8eaf2e3be2fc86240f8833fae3b4 517 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 426 494 2.1E-31 T 29-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CDC59_RS15955 fd2c8eaf2e3be2fc86240f8833fae3b4 517 SMART SM00382 214 348 9.0E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS15955 fd2c8eaf2e3be2fc86240f8833fae3b4 517 Gene3D G3DSA:1.10.1750.10 419 516 1.0E-35 T 29-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CDC59_RS15955 fd2c8eaf2e3be2fc86240f8833fae3b4 517 Pfam PF11638 DnaA N-terminal domain 3 64 1.9E-17 T 29-03-2018 IPR024633 DnaA N-terminal domain CDC59_RS15955 fd2c8eaf2e3be2fc86240f8833fae3b4 517 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 2 516 31.846 T 29-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CDC59_RS15955 fd2c8eaf2e3be2fc86240f8833fae3b4 517 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 279 293 4.3E-49 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CDC59_RS15955 fd2c8eaf2e3be2fc86240f8833fae3b4 517 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 313 340 4.3E-49 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CDC59_RS15955 fd2c8eaf2e3be2fc86240f8833fae3b4 517 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 247 261 4.3E-49 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CDC59_RS15955 fd2c8eaf2e3be2fc86240f8833fae3b4 517 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 475 494 4.3E-49 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CDC59_RS15955 fd2c8eaf2e3be2fc86240f8833fae3b4 517 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 215 235 4.3E-49 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CDC59_RS15955 fd2c8eaf2e3be2fc86240f8833fae3b4 517 ProSitePatterns PS01008 DnaA protein signature. 475 494 - T 29-03-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CDC59_RS15955 fd2c8eaf2e3be2fc86240f8833fae3b4 517 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 5 515 4.5E-169 T 29-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CDC59_RS15955 fd2c8eaf2e3be2fc86240f8833fae3b4 517 Gene3D G3DSA:1.10.8.60 348 418 3.5E-27 T 29-03-2018 CDC59_RS15955 fd2c8eaf2e3be2fc86240f8833fae3b4 517 Pfam PF00308 Bacterial dnaA protein 182 399 3.6E-86 T 29-03-2018 IPR013317 Chromosomal replication initiator protein DnaA CDC59_RS15955 fd2c8eaf2e3be2fc86240f8833fae3b4 517 SMART SM00760 425 494 1.2E-41 T 29-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CDC59_RS15955 fd2c8eaf2e3be2fc86240f8833fae3b4 517 SUPERFAMILY SSF52540 181 393 2.84E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS15955 fd2c8eaf2e3be2fc86240f8833fae3b4 517 Gene3D G3DSA:3.40.50.300 179 346 6.1E-20 T 29-03-2018 CDC59_RS15645 0a1b915e0e7b25b90b00b3c68b1d572d 469 SMART SM00098 36 468 1.3E-116 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CDC59_RS15645 0a1b915e0e7b25b90b00b3c68b1d572d 469 Gene3D G3DSA:3.40.720.10 5 469 6.0E-138 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CDC59_RS15645 0a1b915e0e7b25b90b00b3c68b1d572d 469 PRINTS PR00113 Alkaline phosphatase signature 280 309 1.0E-42 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CDC59_RS15645 0a1b915e0e7b25b90b00b3c68b1d572d 469 PRINTS PR00113 Alkaline phosphatase signature 35 55 1.0E-42 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CDC59_RS15645 0a1b915e0e7b25b90b00b3c68b1d572d 469 PRINTS PR00113 Alkaline phosphatase signature 145 165 1.0E-42 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CDC59_RS15645 0a1b915e0e7b25b90b00b3c68b1d572d 469 PRINTS PR00113 Alkaline phosphatase signature 199 209 1.0E-42 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CDC59_RS15645 0a1b915e0e7b25b90b00b3c68b1d572d 469 Pfam PF00245 Alkaline phosphatase 35 468 1.7E-110 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CDC59_RS15645 0a1b915e0e7b25b90b00b3c68b1d572d 469 SUPERFAMILY SSF53649 14 469 2.13E-137 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CDC59_RS14955 5f682c49e9e1773a26e5a83270f23b29 376 Gene3D G3DSA:2.40.110.10 119 215 3.8E-42 T 29-03-2018 CDC59_RS14955 5f682c49e9e1773a26e5a83270f23b29 376 SUPERFAMILY SSF56645 2 240 2.62E-84 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CDC59_RS14955 5f682c49e9e1773a26e5a83270f23b29 376 PIRSF PIRSF016578 206 371 1.4E-11 T 29-03-2018 CDC59_RS14955 5f682c49e9e1773a26e5a83270f23b29 376 PIRSF PIRSF016578 3 194 1.8E-11 T 29-03-2018 CDC59_RS14955 5f682c49e9e1773a26e5a83270f23b29 376 Gene3D G3DSA:1.20.140.10 216 376 2.4E-59 T 29-03-2018 CDC59_RS14955 5f682c49e9e1773a26e5a83270f23b29 376 SUPERFAMILY SSF47203 227 375 9.67E-58 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CDC59_RS14955 5f682c49e9e1773a26e5a83270f23b29 376 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 227 375 1.3E-51 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CDC59_RS14955 5f682c49e9e1773a26e5a83270f23b29 376 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 120 215 8.9E-28 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CDC59_RS14955 5f682c49e9e1773a26e5a83270f23b29 376 Gene3D G3DSA:1.10.540.10 1 118 5.9E-37 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CDC59_RS14955 5f682c49e9e1773a26e5a83270f23b29 376 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 334 353 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CDC59_RS14955 5f682c49e9e1773a26e5a83270f23b29 376 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 4 116 6.8E-36 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CDC59_RS05980 ec2e7ef64a7758f42cab4629843b13ed 270 Gene3D G3DSA:3.40.50.1820 3 262 1.2E-46 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS05980 ec2e7ef64a7758f42cab4629843b13ed 270 TIGRFAM TIGR02427 protocat_pcaD: 3-oxoadipate enol-lactonase 10 260 6.6E-105 T 29-03-2018 IPR026968 3-oxoadipate enol-lactonase 1/2 GO:0042952|GO:0047570 KEGG: 00362+3.1.1.24|MetaCyc: PWY-6185 CDC59_RS05980 ec2e7ef64a7758f42cab4629843b13ed 270 Pfam PF00561 alpha/beta hydrolase fold 24 246 5.2E-20 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS05980 ec2e7ef64a7758f42cab4629843b13ed 270 SUPERFAMILY SSF53474 1 259 3.86E-55 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS05470 572855b8dcf9581ac79ec7a70359de93 374 Gene3D G3DSA:3.40.640.10 49 258 3.6E-43 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDC59_RS05470 572855b8dcf9581ac79ec7a70359de93 374 SUPERFAMILY SSF53383 15 367 1.31E-83 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS05470 572855b8dcf9581ac79ec7a70359de93 374 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 9 364 1.1E-105 T 29-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CDC59_RS05470 572855b8dcf9581ac79ec7a70359de93 374 Pfam PF00155 Aminotransferase class I and II 36 357 2.1E-55 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CDC59_RS05470 572855b8dcf9581ac79ec7a70359de93 374 Gene3D G3DSA:3.90.1150.10 259 374 8.2E-27 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS05470 572855b8dcf9581ac79ec7a70359de93 374 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 5 367 62.59 T 29-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CDC59_RS05470 572855b8dcf9581ac79ec7a70359de93 374 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 224 233 - T 29-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 CDC59_RS12485 27bd2638d93832c09a5d1efa62414330 298 SUPERFAMILY SSF51735 3 167 9.78E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS12485 27bd2638d93832c09a5d1efa62414330 298 PIRSF PIRSF000103 1 297 5.6E-67 T 29-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CDC59_RS12485 27bd2638d93832c09a5d1efa62414330 298 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 166 1.9E-48 T 29-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CDC59_RS12485 27bd2638d93832c09a5d1efa62414330 298 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 6 19 - T 29-03-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 CDC59_RS12485 27bd2638d93832c09a5d1efa62414330 298 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 169 289 2.6E-27 T 29-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CDC59_RS12485 27bd2638d93832c09a5d1efa62414330 298 Gene3D G3DSA:1.10.1040.10 177 295 1.5E-31 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CDC59_RS12485 27bd2638d93832c09a5d1efa62414330 298 SUPERFAMILY SSF48179 167 290 3.32E-33 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CDC59_RS12485 27bd2638d93832c09a5d1efa62414330 298 Gene3D G3DSA:3.40.50.720 2 176 8.4E-34 T 29-03-2018 CDC59_RS05905 dc022e744868e4121476d2d4638ea1b4 328 SUPERFAMILY SSF48452 207 306 1.82E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS05905 dc022e744868e4121476d2d4638ea1b4 328 Gene3D G3DSA:1.25.40.10 43 324 7.1E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS06005 b5badce4fccebc3b9763444669a35017 233 Pfam PF00005 ABC transporter 20 159 1.9E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS06005 b5badce4fccebc3b9763444669a35017 233 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS06005 b5badce4fccebc3b9763444669a35017 233 SUPERFAMILY SSF52540 4 223 6.35E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS06005 b5badce4fccebc3b9763444669a35017 233 Gene3D G3DSA:3.40.50.300 1 233 5.3E-51 T 29-03-2018 CDC59_RS06005 b5badce4fccebc3b9763444669a35017 233 SMART SM00382 29 209 2.2E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS12970 8980322e61a1f8c479f2544a0415e3fd 189 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 25 151 2.5E-35 T 29-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 CDC59_RS12970 8980322e61a1f8c479f2544a0415e3fd 189 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 26 152 2.1E-36 T 29-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 CDC59_RS12970 8980322e61a1f8c479f2544a0415e3fd 189 Gene3D G3DSA:3.40.50.300 17 187 4.7E-43 T 29-03-2018 CDC59_RS12970 8980322e61a1f8c479f2544a0415e3fd 189 SUPERFAMILY SSF52540 49 151 4.0E-21 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS06675 22edafc3d492d0a89988886b86cafa2c 311 Gene3D G3DSA:3.40.50.620 1 183 3.5E-42 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDC59_RS06675 22edafc3d492d0a89988886b86cafa2c 311 SMART SM00893 3 182 3.3E-57 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CDC59_RS06675 22edafc3d492d0a89988886b86cafa2c 311 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 190 273 7.5E-35 T 29-03-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 CDC59_RS06675 22edafc3d492d0a89988886b86cafa2c 311 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 254 280 - T 29-03-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 CDC59_RS06675 22edafc3d492d0a89988886b86cafa2c 311 SUPERFAMILY SSF52467 187 310 1.04E-46 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CDC59_RS06675 22edafc3d492d0a89988886b86cafa2c 311 Pfam PF01012 Electron transfer flavoprotein domain 4 168 1.7E-39 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CDC59_RS06675 22edafc3d492d0a89988886b86cafa2c 311 PIRSF PIRSF000089 1 311 4.1E-107 T 29-03-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 CDC59_RS06675 22edafc3d492d0a89988886b86cafa2c 311 SUPERFAMILY SSF52402 3 186 1.26E-58 T 29-03-2018 CDC59_RS06675 22edafc3d492d0a89988886b86cafa2c 311 Gene3D G3DSA:3.40.50.1220 185 311 3.0E-59 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CDC59_RS06945 0a241bd316fd0bf5ce88e8c5cb30d9b4 193 Pfam PF02417 Chromate transporter 24 181 2.8E-31 T 29-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 CDC59_RS11385 1bac6baf3c181149878e7aa9c330c374 165 Pfam PF02674 Colicin V production protein 6 147 1.7E-34 T 29-03-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 CDC59_RS01400 5ea62e994ace6c60e67bac560e775958 205 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 14 189 2.3E-61 T 29-03-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CDC59_RS01400 5ea62e994ace6c60e67bac560e775958 205 Pfam PF01583 Adenylylsulphate kinase 24 178 1.2E-58 T 29-03-2018 CDC59_RS01400 5ea62e994ace6c60e67bac560e775958 205 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 22 194 33.181 T 29-03-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CDC59_RS01400 5ea62e994ace6c60e67bac560e775958 205 Gene3D G3DSA:3.40.50.300 20 196 2.1E-39 T 29-03-2018 CDC59_RS01400 5ea62e994ace6c60e67bac560e775958 205 SUPERFAMILY SSF52540 24 191 2.45E-33 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS16605 5ea62e994ace6c60e67bac560e775958 205 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 14 189 2.3E-61 T 29-03-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CDC59_RS16605 5ea62e994ace6c60e67bac560e775958 205 Pfam PF01583 Adenylylsulphate kinase 24 178 1.2E-58 T 29-03-2018 CDC59_RS16605 5ea62e994ace6c60e67bac560e775958 205 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 22 194 33.181 T 29-03-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CDC59_RS16605 5ea62e994ace6c60e67bac560e775958 205 Gene3D G3DSA:3.40.50.300 20 196 2.1E-39 T 29-03-2018 CDC59_RS16605 5ea62e994ace6c60e67bac560e775958 205 SUPERFAMILY SSF52540 24 191 2.45E-33 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS04780 1328661a98009344793340254a24987b 274 ProSitePatterns PS01070 DNA/RNA non-specific endonucleases active site. 143 151 - T 29-03-2018 IPR018524 DNA/RNA non-specific endonuclease, active site GO:0003676|GO:0016787|GO:0046872 CDC59_RS04780 1328661a98009344793340254a24987b 274 Gene3D G3DSA:3.40.570.10 62 272 3.0E-55 T 29-03-2018 CDC59_RS04780 1328661a98009344793340254a24987b 274 SMART SM00892 81 273 8.0E-36 T 29-03-2018 IPR001604 DNA/RNA non-specific endonuclease GO:0003676|GO:0016787|GO:0046872 CDC59_RS04780 1328661a98009344793340254a24987b 274 Pfam PF01223 DNA/RNA non-specific endonuclease 72 271 2.1E-49 T 29-03-2018 IPR001604 DNA/RNA non-specific endonuclease GO:0003676|GO:0016787|GO:0046872 CDC59_RS04780 1328661a98009344793340254a24987b 274 SUPERFAMILY SSF54060 56 271 2.53E-60 T 29-03-2018 CDC59_RS04780 1328661a98009344793340254a24987b 274 SMART SM00477 82 273 4.6E-32 T 29-03-2018 IPR020821 Extracellular Endonuclease, subunit A GO:0003676|GO:0016787|GO:0046872 CDC59_RS20735 97a4cf96eb7e2520ba191e274721c681 1833 Gene3D G3DSA:3.40.50.300 622 1365 4.1E-36 T 29-03-2018 CDC59_RS20735 97a4cf96eb7e2520ba191e274721c681 1833 SUPERFAMILY SSF142921 1768 1825 1.96E-8 T 29-03-2018 IPR008893 WGR domain CDC59_RS20735 97a4cf96eb7e2520ba191e274721c681 1833 SMART SM00773 1757 1832 1.4E-16 T 29-03-2018 IPR008893 WGR domain CDC59_RS20735 97a4cf96eb7e2520ba191e274721c681 1833 Pfam PF13086 AAA domain 627 691 3.4E-8 T 29-03-2018 CDC59_RS20735 97a4cf96eb7e2520ba191e274721c681 1833 Pfam PF13086 AAA domain 1256 1310 8.3E-7 T 29-03-2018 CDC59_RS20735 97a4cf96eb7e2520ba191e274721c681 1833 Gene3D G3DSA:3.40.50.300 1366 1579 1.6E-16 T 29-03-2018 CDC59_RS20735 97a4cf96eb7e2520ba191e274721c681 1833 Pfam PF13195 Protein of unknown function (DUF4011) 330 411 6.7E-10 T 29-03-2018 IPR025103 Protein of unknown function DUF4011 CDC59_RS20735 97a4cf96eb7e2520ba191e274721c681 1833 Gene3D G3DSA:3.40.960.10 1620 1727 1.1E-8 T 29-03-2018 CDC59_RS20735 97a4cf96eb7e2520ba191e274721c681 1833 Pfam PF05406 WGR domain 1767 1829 2.6E-16 T 29-03-2018 IPR008893 WGR domain CDC59_RS20735 97a4cf96eb7e2520ba191e274721c681 1833 SUPERFAMILY SSF52540 1242 1307 1.14E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS20735 97a4cf96eb7e2520ba191e274721c681 1833 SUPERFAMILY SSF52540 814 836 1.14E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS20735 97a4cf96eb7e2520ba191e274721c681 1833 SUPERFAMILY SSF52540 627 692 1.14E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS20735 97a4cf96eb7e2520ba191e274721c681 1833 SUPERFAMILY SSF52540 1349 1560 1.14E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS20735 97a4cf96eb7e2520ba191e274721c681 1833 Pfam PF13087 AAA domain 1340 1561 3.1E-16 T 29-03-2018 CDC59_RS20735 97a4cf96eb7e2520ba191e274721c681 1833 Gene3D G3DSA:2.20.140.10 1761 1832 1.2E-12 T 29-03-2018 IPR008893 WGR domain CDC59_RS00195 42212c0d6a4bbfe3078969681b23f896 218 Gene3D G3DSA:1.10.357.10 84 212 6.3E-14 T 29-03-2018 CDC59_RS00195 42212c0d6a4bbfe3078969681b23f896 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 55 83 4.2E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDC59_RS00195 42212c0d6a4bbfe3078969681b23f896 218 SUPERFAMILY SSF48498 107 217 3.72E-10 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CDC59_RS00195 42212c0d6a4bbfe3078969681b23f896 218 SUPERFAMILY SSF46689 26 99 9.23E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS00195 42212c0d6a4bbfe3078969681b23f896 218 Gene3D G3DSA:1.10.10.60 10 83 1.3E-12 T 29-03-2018 CDC59_RS13725 9a069727e2670b4e01e359d8652137c8 181 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 138 150 2.5E-32 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CDC59_RS13725 9a069727e2670b4e01e359d8652137c8 181 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 83 99 2.5E-32 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CDC59_RS13725 9a069727e2670b4e01e359d8652137c8 181 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 4 17 2.5E-32 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CDC59_RS13725 9a069727e2670b4e01e359d8652137c8 181 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 107 126 2.5E-32 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CDC59_RS13725 9a069727e2670b4e01e359d8652137c8 181 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 61 77 2.5E-32 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CDC59_RS13725 9a069727e2670b4e01e359d8652137c8 181 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 3 150 7.9E-50 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CDC59_RS13725 9a069727e2670b4e01e359d8652137c8 181 SUPERFAMILY SSF53098 1 155 2.78E-54 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDC59_RS13725 9a069727e2670b4e01e359d8652137c8 181 Gene3D G3DSA:3.30.420.10 1 157 1.5E-46 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDC59_RS13725 9a069727e2670b4e01e359d8652137c8 181 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 1 153 46.911 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CDC59_RS13725 9a069727e2670b4e01e359d8652137c8 181 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 3 153 6.2E-52 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CDC59_RS13725 9a069727e2670b4e01e359d8652137c8 181 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 113 147 - T 29-03-2018 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 CDC59_RS16770 0da38422faa93bde9fa7b5bf06a3a455 724 SUPERFAMILY SSF90123 156 463 2.35E-66 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CDC59_RS16770 0da38422faa93bde9fa7b5bf06a3a455 724 SMART SM00382 508 694 9.5E-20 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS16770 0da38422faa93bde9fa7b5bf06a3a455 724 Gene3D G3DSA:3.40.50.300 469 723 7.5E-75 T 29-03-2018 CDC59_RS16770 0da38422faa93bde9fa7b5bf06a3a455 724 SUPERFAMILY SSF52540 475 719 5.11E-88 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS16770 0da38422faa93bde9fa7b5bf06a3a455 724 TIGRFAM TIGR01846 type_I_sec_HlyB: type I secretion system ATPase 25 720 1.8E-304 T 29-03-2018 IPR010132 ATPase, type I secretion system, HlyB GO:0005524|GO:0008565|GO:0016021|GO:0030253|GO:0030256 CDC59_RS16770 0da38422faa93bde9fa7b5bf06a3a455 724 Pfam PF00664 ABC transporter transmembrane region 171 437 2.3E-55 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CDC59_RS16770 0da38422faa93bde9fa7b5bf06a3a455 724 Pfam PF00005 ABC transporter 500 648 9.0E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS16770 0da38422faa93bde9fa7b5bf06a3a455 724 Gene3D G3DSA:1.20.1560.10 153 468 2.5E-47 T 29-03-2018 CDC59_RS16770 0da38422faa93bde9fa7b5bf06a3a455 724 ProSitePatterns PS00211 ABC transporters family signature. 620 634 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS16770 0da38422faa93bde9fa7b5bf06a3a455 724 Gene3D G3DSA:3.90.70.10 17 151 7.1E-19 T 29-03-2018 CDC59_RS16770 0da38422faa93bde9fa7b5bf06a3a455 724 Pfam PF03412 Peptidase C39 family 22 143 4.7E-19 T 29-03-2018 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 CDC59_RS05910 64f0f87765f866f2b8e74681cc86eaaf 529 Pfam PF11997 Domain of unknown function (DUF3492) 11 290 6.2E-106 T 29-03-2018 IPR022622 Domain of unknown function DUF3492 CDC59_RS05910 64f0f87765f866f2b8e74681cc86eaaf 529 Gene3D G3DSA:3.40.50.2000 68 311 2.1E-7 T 29-03-2018 CDC59_RS05910 64f0f87765f866f2b8e74681cc86eaaf 529 Pfam PF00534 Glycosyl transferases group 1 315 469 2.2E-20 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CDC59_RS05910 64f0f87765f866f2b8e74681cc86eaaf 529 Gene3D G3DSA:3.40.50.2000 312 488 5.1E-31 T 29-03-2018 CDC59_RS05910 64f0f87765f866f2b8e74681cc86eaaf 529 SUPERFAMILY SSF53756 159 219 5.1E-54 T 29-03-2018 CDC59_RS05910 64f0f87765f866f2b8e74681cc86eaaf 529 SUPERFAMILY SSF53756 247 503 5.1E-54 T 29-03-2018 CDC59_RS05910 64f0f87765f866f2b8e74681cc86eaaf 529 SUPERFAMILY SSF53756 14 73 5.1E-54 T 29-03-2018 CDC59_RS00155 eb093ebdb727c3a6a48bdcd842d0c77e 215 SUPERFAMILY SSF53335 25 196 2.33E-27 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS00155 eb093ebdb727c3a6a48bdcd842d0c77e 215 Pfam PF07021 Methionine biosynthesis protein MetW 25 212 1.4E-84 T 29-03-2018 IPR010743 Methionine biosynthesis MetW CDC59_RS00155 eb093ebdb727c3a6a48bdcd842d0c77e 215 TIGRFAM TIGR02081 metW: methionine biosynthesis protein MetW 25 212 7.0E-85 T 29-03-2018 IPR010743 Methionine biosynthesis MetW CDC59_RS00155 eb093ebdb727c3a6a48bdcd842d0c77e 215 Gene3D G3DSA:3.40.50.150 10 214 1.9E-20 T 29-03-2018 CDC59_RS03100 9c641f4054a29365aa49395d137baefe 595 Gene3D G3DSA:3.40.710.10 242 591 1.0E-79 T 29-03-2018 CDC59_RS03100 9c641f4054a29365aa49395d137baefe 595 SUPERFAMILY SSF56519 73 240 1.05E-42 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CDC59_RS03100 9c641f4054a29365aa49395d137baefe 595 SUPERFAMILY SSF56601 241 571 5.46E-85 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CDC59_RS03100 9c641f4054a29365aa49395d137baefe 595 Pfam PF03717 Penicillin-binding Protein dimerisation domain 77 225 8.4E-18 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CDC59_RS03100 9c641f4054a29365aa49395d137baefe 595 Gene3D G3DSA:3.90.1310.10 46 241 1.4E-41 T 29-03-2018 CDC59_RS03100 9c641f4054a29365aa49395d137baefe 595 Pfam PF00905 Penicillin binding protein transpeptidase domain 266 561 1.1E-69 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CDC59_RS20465 303e145823cba91614dc184d424913c7 260 SUPERFAMILY SSF88713 1 251 6.37E-89 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CDC59_RS20465 303e145823cba91614dc184d424913c7 260 Gene3D G3DSA:3.20.20.370 2 249 3.9E-91 T 29-03-2018 CDC59_RS20465 303e145823cba91614dc184d424913c7 260 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 1 245 42.786 T 29-03-2018 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF CDC59_RS20465 303e145823cba91614dc184d424913c7 260 Pfam PF03746 LamB/YcsF family 3 240 7.8E-88 T 29-03-2018 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF CDC59_RS13160 3757d2042d4f3a883abef94aea04f006 600 Pfam PF02743 Cache domain 40 256 1.4E-23 T 29-03-2018 IPR033479 Double Cache domain 1 CDC59_RS13160 3757d2042d4f3a883abef94aea04f006 600 Gene3D G3DSA:3.30.450.20 156 274 1.5E-19 T 29-03-2018 CDC59_RS13160 3757d2042d4f3a883abef94aea04f006 600 Gene3D G3DSA:3.30.450.20 28 155 2.0E-24 T 29-03-2018 CDC59_RS13160 3757d2042d4f3a883abef94aea04f006 600 SMART SM00283 350 597 4.4E-94 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CDC59_RS13160 3757d2042d4f3a883abef94aea04f006 600 SMART SM00304 295 349 5.6E-12 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CDC59_RS13160 3757d2042d4f3a883abef94aea04f006 600 SUPERFAMILY SSF58104 317 598 9.42E-78 T 29-03-2018 CDC59_RS13160 3757d2042d4f3a883abef94aea04f006 600 Gene3D G3DSA:1.10.287.950 405 600 1.1E-51 T 29-03-2018 CDC59_RS13160 3757d2042d4f3a883abef94aea04f006 600 Gene3D G3DSA:1.10.287.950 283 404 3.4E-21 T 29-03-2018 CDC59_RS13160 3757d2042d4f3a883abef94aea04f006 600 Pfam PF00672 HAMP domain 299 345 2.7E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CDC59_RS13160 3757d2042d4f3a883abef94aea04f006 600 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 409 565 4.2E-55 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CDC59_RS13160 3757d2042d4f3a883abef94aea04f006 600 SUPERFAMILY SSF103190 89 174 7.46E-13 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CDC59_RS09515 bceffbf1d266e5a9bb313c6c39b43b08 517 Gene3D G3DSA:1.20.1250.20 24 220 2.0E-21 T 29-03-2018 CDC59_RS09515 bceffbf1d266e5a9bb313c6c39b43b08 517 Gene3D G3DSA:1.20.1250.20 272 517 1.2E-9 T 29-03-2018 CDC59_RS09515 bceffbf1d266e5a9bb313c6c39b43b08 517 Pfam PF07690 Major Facilitator Superfamily 40 435 9.4E-30 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDC59_RS09515 bceffbf1d266e5a9bb313c6c39b43b08 517 SUPERFAMILY SSF103473 272 445 6.67E-38 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS09515 bceffbf1d266e5a9bb313c6c39b43b08 517 SUPERFAMILY SSF103473 26 216 6.67E-38 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS09515 bceffbf1d266e5a9bb313c6c39b43b08 517 SUPERFAMILY SSF103473 490 510 6.67E-38 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS03820 22505b90e0b3cb507a1702bed719b599 387 Pfam PF13609 Gram-negative porin 16 349 5.5E-47 T 29-03-2018 CDC59_RS03820 22505b90e0b3cb507a1702bed719b599 387 SUPERFAMILY SSF56935 27 387 2.24E-86 T 29-03-2018 CDC59_RS03820 22505b90e0b3cb507a1702bed719b599 387 Gene3D G3DSA:2.40.160.10 15 387 1.0E-72 T 29-03-2018 CDC59_RS03820 22505b90e0b3cb507a1702bed719b599 387 PRINTS PR00184 Neisseria sp. porin signature 59 84 4.8E-9 T 29-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 CDC59_RS03820 22505b90e0b3cb507a1702bed719b599 387 PRINTS PR00184 Neisseria sp. porin signature 161 178 4.8E-9 T 29-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 CDC59_RS03820 22505b90e0b3cb507a1702bed719b599 387 PRINTS PR00184 Neisseria sp. porin signature 324 348 4.8E-9 T 29-03-2018 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 CDC59_RS14530 3856c30c979ee7e00793a53d0f0c4d67 91 Pfam PF04324 BFD-like [2Fe-2S] binding domain 2 51 2.9E-10 T 29-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain CDC59_RS05095 17a052a5d56964f75f71ba614fd3a3e0 264 SMART SM01007 25 213 2.4E-57 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CDC59_RS05095 17a052a5d56964f75f71ba614fd3a3e0 264 SUPERFAMILY SSF53639 17 238 7.06E-60 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CDC59_RS05095 17a052a5d56964f75f71ba614fd3a3e0 264 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 26 213 4.1E-46 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CDC59_RS05095 17a052a5d56964f75f71ba614fd3a3e0 264 Gene3D G3DSA:3.40.225.10 13 264 2.0E-74 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CDC59_RS09135 28d95a6db989c94aa75953c29ed26316 677 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 524 671 1.2E-33 T 29-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 CDC59_RS09135 28d95a6db989c94aa75953c29ed26316 677 Pfam PF01479 S4 domain 425 471 2.2E-8 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CDC59_RS09135 28d95a6db989c94aa75953c29ed26316 677 Gene3D G3DSA:3.10.290.10 419 492 2.8E-12 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CDC59_RS09135 28d95a6db989c94aa75953c29ed26316 677 SUPERFAMILY SSF55174 425 498 3.14E-14 T 29-03-2018 CDC59_RS09135 28d95a6db989c94aa75953c29ed26316 677 SMART SM00363 425 490 1.1E-4 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CDC59_RS09135 28d95a6db989c94aa75953c29ed26316 677 SUPERFAMILY SSF55120 486 673 2.08E-32 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDC59_RS09135 28d95a6db989c94aa75953c29ed26316 677 Gene3D G3DSA:3.30.70.1560 581 654 3.9E-29 T 29-03-2018 CDC59_RS09135 28d95a6db989c94aa75953c29ed26316 677 Pfam PF00849 RNA pseudouridylate synthase 487 642 2.9E-11 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDC59_RS09135 28d95a6db989c94aa75953c29ed26316 677 Gene3D G3DSA:3.30.70.580 493 580 5.9E-13 T 29-03-2018 CDC59_RS09780 da9b360ba56725032feba9185ab8c13e 145 Pfam PF03061 Thioesterase superfamily 22 108 5.6E-17 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CDC59_RS09780 da9b360ba56725032feba9185ab8c13e 145 SUPERFAMILY SSF54637 3 138 2.19E-41 T 29-03-2018 IPR029069 HotDog domain CDC59_RS09780 da9b360ba56725032feba9185ab8c13e 145 Gene3D G3DSA:3.10.129.10 6 141 2.2E-30 T 29-03-2018 CDC59_RS09780 da9b360ba56725032feba9185ab8c13e 145 PIRSF PIRSF003230 3 140 1.0E-24 T 29-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 CDC59_RS09780 da9b360ba56725032feba9185ab8c13e 145 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 11 126 3.7E-31 T 29-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 CDC59_RS23070 38d471b74e2541a114d1a70c202fa66b 220 Gene3D G3DSA:1.10.287.500 44 176 8.5E-19 T 29-03-2018 CDC59_RS23070 38d471b74e2541a114d1a70c202fa66b 220 Pfam PF04344 Chemotaxis phosphatase, CheZ 24 220 5.1E-77 T 29-03-2018 IPR007439 Chemotaxis phosphatase, CheZ GO:0003824|GO:0009288|GO:0050920 CDC59_RS23070 38d471b74e2541a114d1a70c202fa66b 220 PIRSF PIRSF002884 1 220 3.2E-87 T 29-03-2018 IPR007439 Chemotaxis phosphatase, CheZ GO:0003824|GO:0009288|GO:0050920 CDC59_RS23070 38d471b74e2541a114d1a70c202fa66b 220 Gene3D G3DSA:1.20.5.590 15 42 1.1E-11 T 29-03-2018 CDC59_RS23070 38d471b74e2541a114d1a70c202fa66b 220 SUPERFAMILY SSF75708 20 219 2.48E-65 T 29-03-2018 CDC59_RS07775 6559e7b8854ef7c819b7a14ed3cad936 398 Pfam PF06804 NlpB/DapX lipoprotein 47 390 2.7E-47 T 29-03-2018 IPR010653 NlpB/DapX lipoprotein CDC59_RS18745 1dc5baf006bffbbadf4bcd548ece8acf 299 Gene3D G3DSA:3.20.20.80 70 286 2.5E-11 T 29-03-2018 CDC59_RS18745 1dc5baf006bffbbadf4bcd548ece8acf 299 SUPERFAMILY SSF51445 108 284 1.66E-15 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CDC59_RS06770 9a54abbf1d180fcadba4999bf586ed38 212 Pfam PF00994 Probable molybdopterin binding domain 19 162 3.7E-27 T 29-03-2018 IPR001453 MoaB/Mog domain CDC59_RS06770 9a54abbf1d180fcadba4999bf586ed38 212 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 17 161 2.0E-32 T 29-03-2018 IPR001453 MoaB/Mog domain CDC59_RS06770 9a54abbf1d180fcadba4999bf586ed38 212 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 80 93 - T 29-03-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 CDC59_RS06770 9a54abbf1d180fcadba4999bf586ed38 212 SUPERFAMILY SSF53218 15 203 5.5E-45 T 29-03-2018 IPR001453 MoaB/Mog domain CDC59_RS06770 9a54abbf1d180fcadba4999bf586ed38 212 Gene3D G3DSA:3.40.980.10 10 203 2.8E-37 T 29-03-2018 IPR001453 MoaB/Mog domain CDC59_RS06770 9a54abbf1d180fcadba4999bf586ed38 212 SMART SM00852 18 168 4.0E-22 T 29-03-2018 IPR001453 MoaB/Mog domain CDC59_RS14990 d0484b4e3336856aaff4b83ae4c2c9ab 264 Gene3D G3DSA:1.10.12.10 220 262 2.6E-14 T 29-03-2018 IPR014748 Crontonase, C-terminal CDC59_RS14990 d0484b4e3336856aaff4b83ae4c2c9ab 264 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 260 1.1E-57 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CDC59_RS14990 d0484b4e3336856aaff4b83ae4c2c9ab 264 Gene3D G3DSA:3.90.226.10 6 219 6.0E-60 T 29-03-2018 CDC59_RS14990 d0484b4e3336856aaff4b83ae4c2c9ab 264 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 104 124 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CDC59_RS14990 d0484b4e3336856aaff4b83ae4c2c9ab 264 SUPERFAMILY SSF52096 4 260 3.13E-78 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CDC59_RS17505 f6ec3f3167e3a01cecd5067bf2ba689b 134 SUPERFAMILY SSF55961 2 133 1.29E-37 T 29-03-2018 CDC59_RS17505 f6ec3f3167e3a01cecd5067bf2ba689b 134 Gene3D G3DSA:3.30.530.20 5 134 1.4E-32 T 29-03-2018 IPR023393 START-like domain CDC59_RS17505 f6ec3f3167e3a01cecd5067bf2ba689b 134 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 15 132 7.3E-22 T 29-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CDC59_RS05485 b8522d8fdd68dc955ba0df16a7ca154b 230 Hamap MF_00238 Cytidylate kinase [cmk]. 11 225 32.424 T 29-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CDC59_RS05485 b8522d8fdd68dc955ba0df16a7ca154b 230 Pfam PF02224 Cytidylate kinase 13 221 9.1E-73 T 29-03-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CDC59_RS05485 b8522d8fdd68dc955ba0df16a7ca154b 230 TIGRFAM TIGR00017 cmk: cytidylate kinase 11 219 1.1E-72 T 29-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CDC59_RS05485 b8522d8fdd68dc955ba0df16a7ca154b 230 SUPERFAMILY SSF52540 11 223 2.03E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS05485 b8522d8fdd68dc955ba0df16a7ca154b 230 Gene3D G3DSA:3.40.50.300 9 225 3.4E-44 T 29-03-2018 CDC59_RS20000 ff38a9add63f1d864114dc7bd9dd2b9e 306 Gene3D G3DSA:3.40.50.150 40 292 8.6E-25 T 29-03-2018 CDC59_RS20000 ff38a9add63f1d864114dc7bd9dd2b9e 306 Pfam PF13649 Methyltransferase domain 112 194 6.1E-7 T 29-03-2018 CDC59_RS20000 ff38a9add63f1d864114dc7bd9dd2b9e 306 SUPERFAMILY SSF53335 54 293 9.09E-41 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS02755 dd2def1eac4d6224c69b2fab37931857 659 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 280 334 - T 29-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS02755 dd2def1eac4d6224c69b2fab37931857 659 Gene3D G3DSA:1.20.210.10 43 561 2.5E-185 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS02755 dd2def1eac4d6224c69b2fab37931857 659 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 56 503 7.5E-138 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS02755 dd2def1eac4d6224c69b2fab37931857 659 PRINTS PR01165 Cytochrome c oxidase subunit I signature 166 178 1.8E-96 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS02755 dd2def1eac4d6224c69b2fab37931857 659 PRINTS PR01165 Cytochrome c oxidase subunit I signature 348 369 1.8E-96 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS02755 dd2def1eac4d6224c69b2fab37931857 659 PRINTS PR01165 Cytochrome c oxidase subunit I signature 227 246 1.8E-96 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS02755 dd2def1eac4d6224c69b2fab37931857 659 PRINTS PR01165 Cytochrome c oxidase subunit I signature 383 401 1.8E-96 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS02755 dd2def1eac4d6224c69b2fab37931857 659 PRINTS PR01165 Cytochrome c oxidase subunit I signature 411 430 1.8E-96 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS02755 dd2def1eac4d6224c69b2fab37931857 659 PRINTS PR01165 Cytochrome c oxidase subunit I signature 198 216 1.8E-96 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS02755 dd2def1eac4d6224c69b2fab37931857 659 PRINTS PR01165 Cytochrome c oxidase subunit I signature 278 299 1.8E-96 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS02755 dd2def1eac4d6224c69b2fab37931857 659 PRINTS PR01165 Cytochrome c oxidase subunit I signature 324 339 1.8E-96 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS02755 dd2def1eac4d6224c69b2fab37931857 659 PRINTS PR01165 Cytochrome c oxidase subunit I signature 461 482 1.8E-96 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS02755 dd2def1eac4d6224c69b2fab37931857 659 PRINTS PR01165 Cytochrome c oxidase subunit I signature 47 72 1.8E-96 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS02755 dd2def1eac4d6224c69b2fab37931857 659 PRINTS PR01165 Cytochrome c oxidase subunit I signature 97 120 1.8E-96 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS02755 dd2def1eac4d6224c69b2fab37931857 659 PRINTS PR01165 Cytochrome c oxidase subunit I signature 124 148 1.8E-96 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS02755 dd2def1eac4d6224c69b2fab37931857 659 TIGRFAM TIGR02843 CyoB: cytochrome o ubiquinol oxidase, subunit I 2 648 0.0 T 29-03-2018 IPR014207 Cytochrome o ubiquinol oxidase, subunit I GO:0016682|GO:0055114 MetaCyc: PWY-7544 CDC59_RS02755 dd2def1eac4d6224c69b2fab37931857 659 Gene3D G3DSA:1.10.287.70 575 641 2.2E-17 T 29-03-2018 CDC59_RS02755 dd2def1eac4d6224c69b2fab37931857 659 SUPERFAMILY SSF81442 43 559 9.03E-179 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS00915 4e04fba4b806d2e70c96bbb267c0112f 115 Gene3D G3DSA:3.90.1590.10 1 113 4.8E-28 T 29-03-2018 CDC59_RS00915 4e04fba4b806d2e70c96bbb267c0112f 115 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 25 104 8.7E-9 T 29-03-2018 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 CDC59_RS00915 4e04fba4b806d2e70c96bbb267c0112f 115 SUPERFAMILY SSF51316 1 112 1.67E-32 T 29-03-2018 IPR011057 Mss4-like CDC59_RS15820 f84d1d858381ea78dc7fbcb3c375f62a 802 SUPERFAMILY SSF56601 266 629 1.45E-102 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CDC59_RS15820 f84d1d858381ea78dc7fbcb3c375f62a 802 Pfam PF00905 Penicillin binding protein transpeptidase domain 283 622 1.3E-68 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CDC59_RS15820 f84d1d858381ea78dc7fbcb3c375f62a 802 Pfam PF03717 Penicillin-binding Protein dimerisation domain 61 251 4.0E-44 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CDC59_RS15820 f84d1d858381ea78dc7fbcb3c375f62a 802 Gene3D G3DSA:3.90.1310.10 30 261 6.1E-50 T 29-03-2018 CDC59_RS15820 f84d1d858381ea78dc7fbcb3c375f62a 802 SUPERFAMILY SSF56519 53 265 1.96E-47 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CDC59_RS15820 f84d1d858381ea78dc7fbcb3c375f62a 802 Gene3D G3DSA:3.40.710.10 262 631 4.0E-94 T 29-03-2018 CDC59_RS15820 f84d1d858381ea78dc7fbcb3c375f62a 802 TIGRFAM TIGR03423 pbp2_mrdA: penicillin-binding protein 2 17 627 4.9E-241 T 29-03-2018 IPR017790 Penicillin-binding protein 2 GO:0008658|GO:0016020 CDC59_RS18270 3ce4d8c623ec5cd2d54ac40ecf8475a8 298 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 125 292 9.1E-14 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS18270 3ce4d8c623ec5cd2d54ac40ecf8475a8 298 SUPERFAMILY SSF161098 93 279 3.14E-21 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS18270 3ce4d8c623ec5cd2d54ac40ecf8475a8 298 Gene3D G3DSA:1.10.3720.10 77 293 4.3E-20 T 29-03-2018 CDC59_RS12720 fdf05b090118f3dc77403258c886a3b9 416 SUPERFAMILY SSF53659 2 416 1.4E-143 T 29-03-2018 CDC59_RS12720 fdf05b090118f3dc77403258c886a3b9 416 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 29 410 7.7E-113 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CDC59_RS12720 fdf05b090118f3dc77403258c886a3b9 416 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 303 322 - T 29-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 CDC59_RS12720 fdf05b090118f3dc77403258c886a3b9 416 Gene3D G3DSA:3.40.718.10 9 416 1.0E-128 T 29-03-2018 CDC59_RS12720 fdf05b090118f3dc77403258c886a3b9 416 SMART SM01329 28 412 1.1E-169 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CDC59_RS12720 fdf05b090118f3dc77403258c886a3b9 416 TIGRFAM TIGR00183 prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent 2 416 4.1E-221 T 29-03-2018 IPR004439 Isocitrate dehydrogenase NADP-dependent, dimeric, prokaryotic GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 CDC59_RS14225 7c3a4b8762c4125f9b9d6da6de692883 198 Pfam PF03968 OstA-like protein 38 156 1.1E-26 T 29-03-2018 IPR005653 Organic solvent tolerance-like, N-terminal CDC59_RS14225 7c3a4b8762c4125f9b9d6da6de692883 198 Hamap MF_01914 Lipopolysaccharide export system protein LptA [lptA]. 8 182 25.172 T 29-03-2018 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 CDC59_RS14225 7c3a4b8762c4125f9b9d6da6de692883 198 TIGRFAM TIGR03002 outer_YhbN_LptA: lipopolysaccharide transport periplasmic protein LptA 27 181 4.0E-35 T 29-03-2018 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 CDC59_RS14225 7c3a4b8762c4125f9b9d6da6de692883 198 Gene3D G3DSA:2.60.450.10 27 179 2.3E-24 T 29-03-2018 CDC59_RS11855 e84de1c3876cd06b695486f83ab5608f 173 Gene3D G3DSA:3.30.1450.10 83 160 1.9E-4 T 29-03-2018 CDC59_RS15280 7da95a711ec669e15cd5db02ffde5bdb 455 Gene3D G3DSA:2.160.10.10 241 306 3.8E-14 T 29-03-2018 CDC59_RS15280 7da95a711ec669e15cd5db02ffde5bdb 455 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 1 448 41.418 T 29-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 CDC59_RS15280 7da95a711ec669e15cd5db02ffde5bdb 455 SUPERFAMILY SSF53448 2 248 6.8E-64 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDC59_RS15280 7da95a711ec669e15cd5db02ffde5bdb 455 Gene3D G3DSA:2.160.10.10 307 436 1.1E-33 T 29-03-2018 CDC59_RS15280 7da95a711ec669e15cd5db02ffde5bdb 455 SUPERFAMILY SSF51161 250 433 6.02E-50 T 29-03-2018 IPR011004 Trimeric LpxA-like CDC59_RS15280 7da95a711ec669e15cd5db02ffde5bdb 455 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 391 425 2.2E-6 T 29-03-2018 IPR001451 Hexapeptide repeat CDC59_RS15280 7da95a711ec669e15cd5db02ffde5bdb 455 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 314 347 1.3E-4 T 29-03-2018 IPR001451 Hexapeptide repeat CDC59_RS15280 7da95a711ec669e15cd5db02ffde5bdb 455 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 263 295 3.6E-7 T 29-03-2018 IPR001451 Hexapeptide repeat CDC59_RS15280 7da95a711ec669e15cd5db02ffde5bdb 455 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 2 450 4.8E-190 T 29-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 CDC59_RS15280 7da95a711ec669e15cd5db02ffde5bdb 455 Pfam PF12804 MobA-like NTP transferase domain 4 127 9.1E-23 T 29-03-2018 IPR025877 MobA-like NTP transferase CDC59_RS15280 7da95a711ec669e15cd5db02ffde5bdb 455 Gene3D G3DSA:3.90.550.10 1 240 6.4E-54 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDC59_RS06285 73453f177b36cbc05379640f4db96a78 241 Gene3D G3DSA:1.10.10.200 1 78 6.4E-33 T 29-03-2018 IPR017856 Integrase, N-terminal zinc-binding domain-like CDC59_RS06285 73453f177b36cbc05379640f4db96a78 241 Gene3D G3DSA:3.30.70.980 177 241 9.6E-10 T 29-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS06285 73453f177b36cbc05379640f4db96a78 241 Pfam PF01709 Transcriptional regulator 5 237 1.9E-98 T 29-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS06285 73453f177b36cbc05379640f4db96a78 241 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 237 1.7E-95 T 29-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS06285 73453f177b36cbc05379640f4db96a78 241 SUPERFAMILY SSF75625 3 239 3.14E-98 T 29-03-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS06285 73453f177b36cbc05379640f4db96a78 241 Gene3D G3DSA:3.30.70.980 83 176 2.1E-31 T 29-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS06285 73453f177b36cbc05379640f4db96a78 241 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 239 35.894 T 29-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS02790 d7f852916bfefa9696712a34bfacef0d 862 Pfam PF00535 Glycosyl transferase family 2 274 456 6.2E-17 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CDC59_RS02790 d7f852916bfefa9696712a34bfacef0d 862 Gene3D G3DSA:3.90.550.10 247 533 1.6E-21 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDC59_RS02790 d7f852916bfefa9696712a34bfacef0d 862 SUPERFAMILY SSF53448 272 561 2.59E-27 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDC59_RS02790 d7f852916bfefa9696712a34bfacef0d 862 Hamap MF_01072 Glucans biosynthesis glucosyltransferase H [mdoH]. 112 773 51.262 T 29-03-2018 IPR023725 Glucan biosynthesis glucosyltransferase H GO:0016758 CDC59_RS18610 f8e4566c634105b1defcbdee37d486d7 349 Gene3D G3DSA:3.30.1780.10 2 138 1.4E-28 T 29-03-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 CDC59_RS18610 f8e4566c634105b1defcbdee37d486d7 349 Gene3D G3DSA:3.40.50.720 139 295 1.6E-27 T 29-03-2018 CDC59_RS18610 f8e4566c634105b1defcbdee37d486d7 349 PIRSF PIRSF001439 38 323 4.1E-51 T 29-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CDC59_RS18610 f8e4566c634105b1defcbdee37d486d7 349 SUPERFAMILY SSF51735 4 336 4.93E-97 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS18610 f8e4566c634105b1defcbdee37d486d7 349 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 10 314 1.9E-99 T 29-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CDC59_RS06015 60d3266a4732f8023f2ddfb31fd3fa6c 326 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 36 1.7E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS06015 60d3266a4732f8023f2ddfb31fd3fa6c 326 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 1.7E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS06015 60d3266a4732f8023f2ddfb31fd3fa6c 326 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 46 1.7E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS06015 60d3266a4732f8023f2ddfb31fd3fa6c 326 SUPERFAMILY SSF46785 7 84 3.74E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS06015 60d3266a4732f8023f2ddfb31fd3fa6c 326 Gene3D G3DSA:3.40.190.10 96 186 4.9E-12 T 29-03-2018 CDC59_RS06015 60d3266a4732f8023f2ddfb31fd3fa6c 326 Pfam PF03466 LysR substrate binding domain 99 301 1.8E-19 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS06015 60d3266a4732f8023f2ddfb31fd3fa6c 326 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 68 5.2E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS06015 60d3266a4732f8023f2ddfb31fd3fa6c 326 SUPERFAMILY SSF53850 92 304 1.59E-37 T 29-03-2018 CDC59_RS06015 60d3266a4732f8023f2ddfb31fd3fa6c 326 Gene3D G3DSA:1.10.10.10 2 90 1.6E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS06015 60d3266a4732f8023f2ddfb31fd3fa6c 326 Gene3D G3DSA:3.40.190.10 187 277 3.8E-11 T 29-03-2018 CDC59_RS00190 2e46820c0ca44d86b5290a645005fd3b 447 SUPERFAMILY SSF53649 276 382 6.08E-5 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CDC59_RS00190 2e46820c0ca44d86b5290a645005fd3b 447 Gene3D G3DSA:3.40.720.10 102 385 2.6E-16 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CDC59_RS00190 2e46820c0ca44d86b5290a645005fd3b 447 Pfam PF04185 Phosphoesterase family 4 371 3.6E-52 T 29-03-2018 IPR007312 Phosphoesterase GO:0016788 CDC59_RS11400 aba83738c43fcfb5bfe9e5cc4d717a8a 290 Pfam PF01039 Carboxyl transferase domain 108 242 1.5E-13 T 29-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 CDC59_RS11400 aba83738c43fcfb5bfe9e5cc4d717a8a 290 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 1 283 37.979 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CDC59_RS11400 aba83738c43fcfb5bfe9e5cc4d717a8a 290 SUPERFAMILY SSF52096 27 284 4.97E-85 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CDC59_RS11400 aba83738c43fcfb5bfe9e5cc4d717a8a 290 Gene3D G3DSA:3.90.226.10 15 290 9.7E-69 T 29-03-2018 CDC59_RS11400 aba83738c43fcfb5bfe9e5cc4d717a8a 290 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 1 285 1.5E-127 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CDC59_RS11400 aba83738c43fcfb5bfe9e5cc4d717a8a 290 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 253 262 5.5E-39 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CDC59_RS11400 aba83738c43fcfb5bfe9e5cc4d717a8a 290 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 202 219 5.5E-39 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CDC59_RS11400 aba83738c43fcfb5bfe9e5cc4d717a8a 290 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 231 242 5.5E-39 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CDC59_RS11400 aba83738c43fcfb5bfe9e5cc4d717a8a 290 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 165 183 5.5E-39 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CDC59_RS11400 aba83738c43fcfb5bfe9e5cc4d717a8a 290 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 131 145 5.5E-39 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CDC59_RS20320 89bbdcb2c5a6c5950b174bced5d91a83 529 ProSitePatterns PS00502 Polygalacturonase active site. 324 337 - T 29-03-2018 IPR000743 Glycoside hydrolase, family 28 GO:0004650|GO:0005975 CDC59_RS20320 89bbdcb2c5a6c5950b174bced5d91a83 529 Gene3D G3DSA:2.160.20.10 65 466 4.4E-68 T 29-03-2018 IPR012334 Pectin lyase fold CDC59_RS20320 89bbdcb2c5a6c5950b174bced5d91a83 529 SUPERFAMILY SSF51126 279 462 1.93E-56 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CDC59_RS20320 89bbdcb2c5a6c5950b174bced5d91a83 529 SUPERFAMILY SSF51126 68 249 1.93E-56 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CDC59_RS20320 89bbdcb2c5a6c5950b174bced5d91a83 529 Pfam PF00295 Glycosyl hydrolases family 28 90 455 1.7E-51 T 29-03-2018 IPR000743 Glycoside hydrolase, family 28 GO:0004650|GO:0005975 CDC59_RS22520 ec3205a2e3624dff6a6dee4ba1052d04 158 SUPERFAMILY SSF55298 36 157 3.46E-34 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CDC59_RS22520 ec3205a2e3624dff6a6dee4ba1052d04 158 Pfam PF01042 Endoribonuclease L-PSP 49 156 3.7E-27 T 29-03-2018 IPR006175 YjgF/YER057c/UK114 family CDC59_RS22520 ec3205a2e3624dff6a6dee4ba1052d04 158 Gene3D G3DSA:3.30.1330.40 26 158 2.4E-31 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CDC59_RS20795 9e367892b68002938f2ec91c02bc8e7e 203 Pfam PF02397 Bacterial sugar transferase 3 177 6.2E-62 T 29-03-2018 IPR003362 Bacterial sugar transferase CDC59_RS07530 16fad83930500cf15a4136f77091c04c 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 3.0E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS07530 16fad83930500cf15a4136f77091c04c 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 2.0E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS07530 16fad83930500cf15a4136f77091c04c 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 2.0E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS07530 16fad83930500cf15a4136f77091c04c 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 2.0E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS07530 16fad83930500cf15a4136f77091c04c 300 SUPERFAMILY SSF53850 90 296 2.25E-46 T 29-03-2018 CDC59_RS07530 16fad83930500cf15a4136f77091c04c 300 Pfam PF03466 LysR substrate binding domain 98 298 4.1E-27 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS07530 16fad83930500cf15a4136f77091c04c 300 Gene3D G3DSA:1.10.10.10 1 88 3.3E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS07530 16fad83930500cf15a4136f77091c04c 300 Gene3D G3DSA:3.40.190.10 94 178 2.3E-15 T 29-03-2018 CDC59_RS07530 16fad83930500cf15a4136f77091c04c 300 SUPERFAMILY SSF46785 5 85 7.58E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS07530 16fad83930500cf15a4136f77091c04c 300 Gene3D G3DSA:3.40.190.10 179 270 1.3E-15 T 29-03-2018 CDC59_RS16735 3bbda90179d24a2e26c0be50e970b5a3 293 Gene3D G3DSA:3.40.50.2300 1 130 8.1E-6 T 29-03-2018 CDC59_RS16735 3bbda90179d24a2e26c0be50e970b5a3 293 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 148 162 9.6E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS16735 3bbda90179d24a2e26c0be50e970b5a3 293 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 178 9.6E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS16735 3bbda90179d24a2e26c0be50e970b5a3 293 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 190 9.6E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS16735 3bbda90179d24a2e26c0be50e970b5a3 293 Gene3D G3DSA:1.10.10.10 148 207 1.6E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS16735 3bbda90179d24a2e26c0be50e970b5a3 293 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 200 3.8E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS16735 3bbda90179d24a2e26c0be50e970b5a3 293 SMART SM00421 145 202 3.7E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS16735 3bbda90179d24a2e26c0be50e970b5a3 293 SUPERFAMILY SSF46894 134 207 5.1E-16 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CDC59_RS16735 3bbda90179d24a2e26c0be50e970b5a3 293 SUPERFAMILY SSF52172 1 123 3.69E-8 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS14280 8ae9c83817e28a988203386006a8f5fa 288 SMART SM00898 2 130 8.5E-47 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CDC59_RS14280 8ae9c83817e28a988203386006a8f5fa 288 Gene3D G3DSA:3.20.190.10 2 142 5.4E-34 T 29-03-2018 CDC59_RS14280 8ae9c83817e28a988203386006a8f5fa 288 SUPERFAMILY SSF57716 236 287 5.23E-18 T 29-03-2018 CDC59_RS14280 8ae9c83817e28a988203386006a8f5fa 288 Pfam PF06827 Zinc finger found in FPG and IleRS 260 287 1.7E-11 T 29-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 CDC59_RS14280 8ae9c83817e28a988203386006a8f5fa 288 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 129 5.6E-29 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CDC59_RS14280 8ae9c83817e28a988203386006a8f5fa 288 ProSitePatterns PS01242 Zinc finger FPG-type signature. 263 287 - T 29-03-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 CDC59_RS14280 8ae9c83817e28a988203386006a8f5fa 288 SUPERFAMILY SSF46946 149 240 2.8E-25 T 29-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CDC59_RS14280 8ae9c83817e28a988203386006a8f5fa 288 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 288 41.532 T 29-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 CDC59_RS14280 8ae9c83817e28a988203386006a8f5fa 288 SUPERFAMILY SSF81624 2 135 3.4E-34 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CDC59_RS14280 8ae9c83817e28a988203386006a8f5fa 288 Gene3D G3DSA:1.10.8.50 143 288 8.4E-44 T 29-03-2018 CDC59_RS14280 8ae9c83817e28a988203386006a8f5fa 288 SMART SM01232 148 240 3.7E-41 T 29-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CDC59_RS14280 8ae9c83817e28a988203386006a8f5fa 288 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 148 237 2.5E-18 T 29-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CDC59_RS14280 8ae9c83817e28a988203386006a8f5fa 288 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 287 5.4E-74 T 29-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 CDC59_RS07155 bc5e7ae7b9b11a1d0a645251fae207f9 106 Gene3D G3DSA:2.60.300.12 1 106 6.4E-39 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CDC59_RS07155 bc5e7ae7b9b11a1d0a645251fae207f9 106 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 87 104 - T 29-03-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 CDC59_RS07155 bc5e7ae7b9b11a1d0a645251fae207f9 106 SUPERFAMILY SSF89360 1 95 4.97E-33 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CDC59_RS07155 bc5e7ae7b9b11a1d0a645251fae207f9 106 Pfam PF01521 Iron-sulphur cluster biosynthesis 2 102 1.5E-24 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CDC59_RS07155 bc5e7ae7b9b11a1d0a645251fae207f9 106 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 2 106 6.1E-38 T 29-03-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 CDC59_RS07155 bc5e7ae7b9b11a1d0a645251fae207f9 106 TIGRFAM TIGR02011 IscA: iron-sulfur cluster assembly protein IscA 2 106 1.6E-53 T 29-03-2018 IPR011302 Iron-binding protein IscA, proteobacteria GO:0005506|GO:0051536|GO:0097428 CDC59_RS22850 72aefadc32eb7dfb783155345ebeeb2c 494 Pfam PF07171 MlrC C-terminus 303 476 3.6E-54 T 29-03-2018 IPR010799 Microcystin LR degradation protein MlrC, C-terminal CDC59_RS22850 72aefadc32eb7dfb783155345ebeeb2c 494 Pfam PF07364 Metallopeptidase family M81 2 290 1.7E-95 T 29-03-2018 IPR015995 Microcystin LR degradation protein MlrC, N-terminal CDC59_RS22850 72aefadc32eb7dfb783155345ebeeb2c 494 Gene3D G3DSA:3.40.640.10 21 222 0.0078 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDC59_RS22850 72aefadc32eb7dfb783155345ebeeb2c 494 PIRSF PIRSF012702 1 493 6.3E-163 T 29-03-2018 IPR009197 Microcystin LR degradation protein MlrC CDC59_RS22850 72aefadc32eb7dfb783155345ebeeb2c 494 Gene3D G3DSA:3.40.640.10 238 415 0.018 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDC59_RS05260 1d49b71a4f5ac0565d84af9b5cc05935 91 Gene3D G3DSA:4.10.520.10 1 91 7.8E-28 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CDC59_RS05260 1d49b71a4f5ac0565d84af9b5cc05935 91 SMART SM00411 1 90 7.7E-31 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CDC59_RS05260 1d49b71a4f5ac0565d84af9b5cc05935 91 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 4.9E-10 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CDC59_RS05260 1d49b71a4f5ac0565d84af9b5cc05935 91 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 4.9E-10 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CDC59_RS05260 1d49b71a4f5ac0565d84af9b5cc05935 91 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 4.9E-10 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CDC59_RS05260 1d49b71a4f5ac0565d84af9b5cc05935 91 SUPERFAMILY SSF47729 1 89 5.59E-27 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CDC59_RS05260 1d49b71a4f5ac0565d84af9b5cc05935 91 Pfam PF00216 Bacterial DNA-binding protein 1 89 1.9E-28 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CDC59_RS18820 e39e1d1b52a64060c933e549115965cf 143 Pfam PF02082 Transcriptional regulator 1 81 3.2E-22 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type CDC59_RS18820 e39e1d1b52a64060c933e549115965cf 143 SUPERFAMILY SSF46785 6 131 6.39E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS18820 e39e1d1b52a64060c933e549115965cf 143 Gene3D G3DSA:1.10.10.10 1 143 1.7E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS19740 aa0e1a91a3f3047d7b36b5fe604333f9 1309 Gene3D G3DSA:3.40.50.300 123 650 4.9E-7 T 29-03-2018 CDC59_RS19740 aa0e1a91a3f3047d7b36b5fe604333f9 1309 Pfam PF14331 ImcF-related N-terminal domain 184 439 1.5E-82 T 29-03-2018 IPR025743 ImcF-related, N-terminal domain CDC59_RS19740 aa0e1a91a3f3047d7b36b5fe604333f9 1309 SUPERFAMILY SSF52540 119 272 1.27E-7 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS19740 aa0e1a91a3f3047d7b36b5fe604333f9 1309 Pfam PF06744 Type VI secretion protein IcmF C-terminal 1001 1205 1.5E-49 T 29-03-2018 IPR010623 Type VI secretion system IcmF, C-terminal CDC59_RS19740 aa0e1a91a3f3047d7b36b5fe604333f9 1309 TIGRFAM TIGR03348 VI_IcmF: type VI secretion protein IcmF 41 560 4.1E-139 T 29-03-2018 IPR017731 Type VI secretion system, IcmF CDC59_RS19740 aa0e1a91a3f3047d7b36b5fe604333f9 1309 Pfam PF06761 Intracellular multiplication and human macrophage-killing 488 860 1.0E-95 T 29-03-2018 IPR009612 ImcF-related CDC59_RS17940 88a2d047a8353d39fefa5f44431ce30d 399 Gene3D G3DSA:1.20.1250.20 6 201 2.0E-17 T 29-03-2018 CDC59_RS17940 88a2d047a8353d39fefa5f44431ce30d 399 SUPERFAMILY SSF103473 8 386 8.11E-38 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS17940 88a2d047a8353d39fefa5f44431ce30d 399 Pfam PF07690 Major Facilitator Superfamily 14 244 5.5E-17 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDC59_RS17940 88a2d047a8353d39fefa5f44431ce30d 399 Gene3D G3DSA:1.20.1250.20 202 390 1.7E-16 T 29-03-2018 CDC59_RS16400 6428f7e34dc4f97b778026efe19281d6 103 Gene3D G3DSA:1.10.1220.10 6 45 2.2E-4 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CDC59_RS16400 6428f7e34dc4f97b778026efe19281d6 103 TIGRFAM TIGR02384 RelB_DinJ: addiction module antitoxin, RelB/DinJ family 8 88 9.2E-20 T 29-03-2018 IPR007337 RelB antitoxin/Antitoxin DinJ CDC59_RS16400 6428f7e34dc4f97b778026efe19281d6 103 PIRSF PIRSF003108 5 92 7.6E-25 T 29-03-2018 IPR026262 Antitoxin DinJ GO:0000986|GO:0015643|GO:0044010 CDC59_RS16400 6428f7e34dc4f97b778026efe19281d6 103 Pfam PF04221 RelB antitoxin 11 85 4.1E-19 T 29-03-2018 IPR007337 RelB antitoxin/Antitoxin DinJ CDC59_RS05035 993cee935dc39c0f60b098ca77d1516a 406 SUPERFAMILY SSF89796 1 406 2.35E-152 T 29-03-2018 IPR023606 CoA-transferase family III domain CDC59_RS05035 993cee935dc39c0f60b098ca77d1516a 406 Pfam PF02515 CoA-transferase family III 4 382 5.1E-137 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 CDC59_RS05035 993cee935dc39c0f60b098ca77d1516a 406 Gene3D G3DSA:3.40.50.10540 1 406 3.5E-163 T 29-03-2018 IPR023606 CoA-transferase family III domain CDC59_RS13000 c62a23640a2e2e2eeab52d8341a59abe 207 Pfam PF02660 Glycerol-3-phosphate acyltransferase 14 192 1.1E-47 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CDC59_RS13000 c62a23640a2e2e2eeab52d8341a59abe 207 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 9 201 19.839 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CDC59_RS13000 c62a23640a2e2e2eeab52d8341a59abe 207 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 8 202 2.0E-56 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CDC59_RS13000 c62a23640a2e2e2eeab52d8341a59abe 207 SMART SM01207 12 193 3.8E-81 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CDC59_RS17770 73600672dc8c6fa5eca7720bae366609 773 SUPERFAMILY SSF51445 183 623 2.81E-128 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CDC59_RS17770 73600672dc8c6fa5eca7720bae366609 773 SUPERFAMILY SSF51445 685 757 2.81E-128 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CDC59_RS17770 73600672dc8c6fa5eca7720bae366609 773 Gene3D G3DSA:3.20.20.80 179 763 8.2E-139 T 29-03-2018 CDC59_RS17770 73600672dc8c6fa5eca7720bae366609 773 TIGRFAM TIGR00217 malQ: 4-alpha-glucanotransferase 141 667 2.6E-86 T 29-03-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 CDC59_RS17770 73600672dc8c6fa5eca7720bae366609 773 Pfam PF02446 4-alpha-glucanotransferase 205 741 9.6E-104 T 29-03-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 CDC59_RS01105 218936603292d720b65f87b13572aedc 336 SUPERFAMILY SSF49785 180 334 8.93E-56 T 29-03-2018 IPR008979 Galactose-binding domain-like CDC59_RS01105 218936603292d720b65f87b13572aedc 336 TIGRFAM TIGR02961 allantoicase: allantoicase 17 333 4.1E-140 T 29-03-2018 IPR005164 Allantoicase GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 CDC59_RS01105 218936603292d720b65f87b13572aedc 336 Pfam PF03561 Allantoicase repeat 193 333 1.0E-47 T 29-03-2018 IPR015908 Allantoicase domain GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 CDC59_RS01105 218936603292d720b65f87b13572aedc 336 Pfam PF03561 Allantoicase repeat 26 170 5.7E-47 T 29-03-2018 IPR015908 Allantoicase domain GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 CDC59_RS01105 218936603292d720b65f87b13572aedc 336 PIRSF PIRSF016516 1 336 6.1E-151 T 29-03-2018 IPR005164 Allantoicase GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 CDC59_RS01105 218936603292d720b65f87b13572aedc 336 SUPERFAMILY SSF49785 12 173 3.49E-59 T 29-03-2018 IPR008979 Galactose-binding domain-like CDC59_RS01105 218936603292d720b65f87b13572aedc 336 Hamap MF_00813 Probable allantoicase [alc]. 6 336 47.932 T 29-03-2018 IPR005164 Allantoicase GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 CDC59_RS01105 218936603292d720b65f87b13572aedc 336 Gene3D G3DSA:2.60.120.260 6 173 8.4E-62 T 29-03-2018 IPR008979 Galactose-binding domain-like CDC59_RS01105 218936603292d720b65f87b13572aedc 336 Gene3D G3DSA:2.60.120.260 174 336 6.6E-62 T 29-03-2018 IPR008979 Galactose-binding domain-like CDC59_RS16975 c884d942001b5e5b87811748c774e9f4 242 Pfam PF07702 UTRA domain 100 230 1.0E-20 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CDC59_RS16975 c884d942001b5e5b87811748c774e9f4 242 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 30 44 3.6E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDC59_RS16975 c884d942001b5e5b87811748c774e9f4 242 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 44 60 3.6E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDC59_RS16975 c884d942001b5e5b87811748c774e9f4 242 Gene3D G3DSA:1.10.10.10 1 77 1.2E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS16975 c884d942001b5e5b87811748c774e9f4 242 SUPERFAMILY SSF64288 58 237 7.85E-27 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CDC59_RS16975 c884d942001b5e5b87811748c774e9f4 242 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 70 4.1E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDC59_RS16975 c884d942001b5e5b87811748c774e9f4 242 SMART SM00345 11 70 6.3E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDC59_RS16975 c884d942001b5e5b87811748c774e9f4 242 SMART SM00866 94 231 6.0E-14 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CDC59_RS16975 c884d942001b5e5b87811748c774e9f4 242 Gene3D G3DSA:3.40.1410.10 97 237 1.4E-24 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CDC59_RS16975 c884d942001b5e5b87811748c774e9f4 242 SUPERFAMILY SSF46785 2 73 3.58E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS21235 d9b7906ecc49ff36855ed4692937720b 248 Pfam PF06314 Acetoacetate decarboxylase (ADC) 13 245 5.1E-80 T 29-03-2018 IPR010451 Acetoacetate decarboxylase GO:0016829 KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 CDC59_RS21235 d9b7906ecc49ff36855ed4692937720b 248 Hamap MF_00597 Probable acetoacetate decarboxylase [adc]. 7 246 57.396 T 29-03-2018 IPR023653 Acetoacetate decarboxylase, bacterial GO:0016831 KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 CDC59_RS21235 d9b7906ecc49ff36855ed4692937720b 248 Gene3D G3DSA:2.40.400.10 7 248 1.0E-64 T 29-03-2018 IPR023375 Acetoacetate decarboxylase beta barrel domain KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 CDC59_RS21235 d9b7906ecc49ff36855ed4692937720b 248 SUPERFAMILY SSF160104 2 245 6.54E-89 T 29-03-2018 IPR023375 Acetoacetate decarboxylase beta barrel domain KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 CDC59_RS19255 7c36ece571f0a40f6d81d97a9ae4d03b 1665 Pfam PF05088 Bacterial NAD-glutamate dehydrogenase 76 1660 0.0 T 29-03-2018 IPR028971 NAD-glutamate dehydrogenase GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 CDC59_RS19255 7c36ece571f0a40f6d81d97a9ae4d03b 1665 Gene3D G3DSA:3.40.50.720 999 1307 5.3E-52 T 29-03-2018 CDC59_RS19255 7c36ece571f0a40f6d81d97a9ae4d03b 1665 SUPERFAMILY SSF53223 825 1002 2.21E-25 T 29-03-2018 CDC59_RS19255 7c36ece571f0a40f6d81d97a9ae4d03b 1665 SUPERFAMILY SSF51735 1144 1348 2.3E-34 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS19255 7c36ece571f0a40f6d81d97a9ae4d03b 1665 SUPERFAMILY SSF51735 1006 1108 2.3E-34 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS19255 7c36ece571f0a40f6d81d97a9ae4d03b 1665 PIRSF PIRSF036761 3 591 6.6E-145 T 29-03-2018 IPR007780 NAD-glutamate dehydrogenase, bacteria GO:0004352|GO:0019551 CDC59_RS19255 7c36ece571f0a40f6d81d97a9ae4d03b 1665 PIRSF PIRSF036761 579 1665 0.0 T 29-03-2018 IPR007780 NAD-glutamate dehydrogenase, bacteria GO:0004352|GO:0019551 CDC59_RS08335 9f420dea02972b6baf4d111e8309ad07 669 Gene3D G3DSA:3.40.1190.20 11 341 2.5E-58 T 29-03-2018 IPR029056 Ribokinase-like CDC59_RS08335 9f420dea02972b6baf4d111e8309ad07 669 Pfam PF00294 pfkB family carbohydrate kinase 12 328 6.8E-47 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB CDC59_RS08335 9f420dea02972b6baf4d111e8309ad07 669 TIGRFAM TIGR04382 myo_inos_iolC_N: 5-dehydro-2-deoxygluconokinase 11 335 1.9E-114 T 29-03-2018 IPR030830 5-Dehydro-2-deoxygluconokinase KEGG: 00562+2.7.1.92 CDC59_RS08335 9f420dea02972b6baf4d111e8309ad07 669 Pfam PF09863 Uncharacterized protein conserved in bacteria (DUF2090) 331 640 5.6E-131 T 29-03-2018 IPR018659 Protein of unknown function DUF2090 CDC59_RS08335 9f420dea02972b6baf4d111e8309ad07 669 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 280 293 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CDC59_RS08335 9f420dea02972b6baf4d111e8309ad07 669 SUPERFAMILY SSF53613 10 333 2.34E-66 T 29-03-2018 IPR029056 Ribokinase-like CDC59_RS08335 9f420dea02972b6baf4d111e8309ad07 669 Gene3D G3DSA:3.20.20.70 350 655 1.1E-59 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS22105 0ca65547934e148077c25bda4dc54efa 216 SUPERFAMILY SSF89562 16 177 1.11E-48 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CDC59_RS22105 0ca65547934e148077c25bda4dc54efa 216 Pfam PF03737 Aldolase/RraA 19 167 6.5E-41 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CDC59_RS22105 0ca65547934e148077c25bda4dc54efa 216 Gene3D G3DSA:3.50.30.40 12 187 2.4E-53 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CDC59_RS11195 302b07f82b82ad9e9ca66f5c326b824f 635 SUPERFAMILY SSF53474 418 430 1.88E-25 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS11195 302b07f82b82ad9e9ca66f5c326b824f 635 SUPERFAMILY SSF53474 294 389 1.88E-25 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS11195 302b07f82b82ad9e9ca66f5c326b824f 635 SUPERFAMILY SSF53474 68 260 1.88E-25 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS11195 302b07f82b82ad9e9ca66f5c326b824f 635 Pfam PF08840 BAAT / Acyl-CoA thioester hydrolase C terminal 205 433 2.2E-58 T 29-03-2018 IPR014940 BAAT/Acyl-CoA thioester hydrolase C-terminal CDC59_RS11195 302b07f82b82ad9e9ca66f5c326b824f 635 Pfam PF04775 Acyl-CoA thioester hydrolase/BAAT N-terminal region 19 139 1.8E-33 T 29-03-2018 IPR006862 Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase CDC59_RS11195 302b07f82b82ad9e9ca66f5c326b824f 635 Gene3D G3DSA:3.40.50.1820 129 432 4.7E-24 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS11195 302b07f82b82ad9e9ca66f5c326b824f 635 Gene3D G3DSA:1.20.1290.10 497 621 2.5E-12 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CDC59_RS11195 302b07f82b82ad9e9ca66f5c326b824f 635 SUPERFAMILY SSF69118 471 610 1.76E-17 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CDC59_RS19135 8f4b98aa6017f101f132184e59e7496a 284 SMART SM00382 43 232 2.9E-19 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS19135 8f4b98aa6017f101f132184e59e7496a 284 SUPERFAMILY SSF52540 19 254 2.97E-73 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS19135 8f4b98aa6017f101f132184e59e7496a 284 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS19135 8f4b98aa6017f101f132184e59e7496a 284 PIRSF PIRSF039085 15 260 5.3E-99 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CDC59_RS19135 8f4b98aa6017f101f132184e59e7496a 284 Pfam PF00005 ABC transporter 34 184 1.2E-36 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS19135 8f4b98aa6017f101f132184e59e7496a 284 Gene3D G3DSA:3.40.50.300 16 272 2.2E-73 T 29-03-2018 CDC59_RS02040 ebb729b5bbbcecd09693dfb2b544e99a 280 Gene3D G3DSA:1.10.3720.10 5 269 2.3E-39 T 29-03-2018 CDC59_RS02040 ebb729b5bbbcecd09693dfb2b544e99a 280 SUPERFAMILY SSF161098 10 279 6.45E-63 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS02040 ebb729b5bbbcecd09693dfb2b544e99a 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 96 272 3.2E-11 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS03110 bf4d4d77053953712c78d9d7d4bc12f3 482 Gene3D G3DSA:3.40.1190.10 101 324 4.3E-50 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CDC59_RS03110 bf4d4d77053953712c78d9d7d4bc12f3 482 SUPERFAMILY SSF53623 111 326 2.09E-45 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CDC59_RS03110 bf4d4d77053953712c78d9d7d4bc12f3 482 SUPERFAMILY SSF63418 13 108 1.01E-24 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CDC59_RS03110 bf4d4d77053953712c78d9d7d4bc12f3 482 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 9 461 32.773 T 29-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDC59_RS03110 bf4d4d77053953712c78d9d7d4bc12f3 482 SUPERFAMILY SSF53244 328 460 9.16E-40 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CDC59_RS03110 bf4d4d77053953712c78d9d7d4bc12f3 482 Pfam PF02875 Mur ligase family, glutamate ligase domain 328 405 3.1E-14 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CDC59_RS03110 bf4d4d77053953712c78d9d7d4bc12f3 482 Pfam PF01225 Mur ligase family, catalytic domain 30 106 1.2E-12 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CDC59_RS03110 bf4d4d77053953712c78d9d7d4bc12f3 482 Gene3D G3DSA:3.40.1390.10 6 100 1.6E-28 T 29-03-2018 CDC59_RS03110 bf4d4d77053953712c78d9d7d4bc12f3 482 Pfam PF08245 Mur ligase middle domain 116 308 1.2E-38 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CDC59_RS03110 bf4d4d77053953712c78d9d7d4bc12f3 482 Gene3D G3DSA:3.90.190.20 328 472 4.6E-48 T 29-03-2018 CDC59_RS03110 bf4d4d77053953712c78d9d7d4bc12f3 482 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 35 460 1.3E-127 T 29-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDC59_RS15695 6e22ee0af73a8fd72f427a67b8593513 229 Pfam PF13417 Glutathione S-transferase, N-terminal domain 9 78 4.8E-12 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CDC59_RS15695 6e22ee0af73a8fd72f427a67b8593513 229 Gene3D G3DSA:1.20.1050.10 98 206 3.0E-18 T 29-03-2018 CDC59_RS15695 6e22ee0af73a8fd72f427a67b8593513 229 SUPERFAMILY SSF47616 82 199 4.26E-17 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like CDC59_RS15695 6e22ee0af73a8fd72f427a67b8593513 229 Gene3D G3DSA:3.40.30.10 1 97 3.8E-24 T 29-03-2018 CDC59_RS15695 6e22ee0af73a8fd72f427a67b8593513 229 SUPERFAMILY SSF52833 2 85 5.72E-20 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS09865 46505a30e5dd1d85662c3aab0e4050fc 265 SUPERFAMILY SSF161098 2 253 3.36E-47 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS09865 46505a30e5dd1d85662c3aab0e4050fc 265 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 78 250 4.4E-16 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS09865 46505a30e5dd1d85662c3aab0e4050fc 265 Gene3D G3DSA:1.10.3720.10 5 260 1.3E-38 T 29-03-2018 CDC59_RS18105 e055bb405a118b68109a4868e264e84e 134 SUPERFAMILY SSF52540 31 105 9.74E-8 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS18105 e055bb405a118b68109a4868e264e84e 134 Pfam PF13087 AAA domain 19 100 1.8E-9 T 29-03-2018 CDC59_RS18105 e055bb405a118b68109a4868e264e84e 134 Gene3D G3DSA:3.40.50.300 4 110 5.0E-15 T 29-03-2018 CDC59_RS00145 57c37cff4fccccdf93d7e20d6157a211 252 Pfam PF08238 Sel1 repeat 114 148 1.5E-5 T 29-03-2018 IPR006597 Sel1-like repeat CDC59_RS00145 57c37cff4fccccdf93d7e20d6157a211 252 Pfam PF08238 Sel1 repeat 150 184 3.6E-10 T 29-03-2018 IPR006597 Sel1-like repeat CDC59_RS00145 57c37cff4fccccdf93d7e20d6157a211 252 Pfam PF08238 Sel1 repeat 187 222 2.0E-6 T 29-03-2018 IPR006597 Sel1-like repeat CDC59_RS00145 57c37cff4fccccdf93d7e20d6157a211 252 Pfam PF08238 Sel1 repeat 79 110 3.5E-5 T 29-03-2018 IPR006597 Sel1-like repeat CDC59_RS00145 57c37cff4fccccdf93d7e20d6157a211 252 Gene3D G3DSA:2.60.40.1180 202 240 0.0047 T 29-03-2018 CDC59_RS00145 57c37cff4fccccdf93d7e20d6157a211 252 Gene3D G3DSA:2.60.40.1180 49 144 3.4E-16 T 29-03-2018 CDC59_RS00145 57c37cff4fccccdf93d7e20d6157a211 252 Gene3D G3DSA:2.60.40.1180 145 201 2.2E-16 T 29-03-2018 CDC59_RS00145 57c37cff4fccccdf93d7e20d6157a211 252 SMART SM00671 185 222 6.8E-6 T 29-03-2018 IPR006597 Sel1-like repeat CDC59_RS00145 57c37cff4fccccdf93d7e20d6157a211 252 SMART SM00671 149 184 4.7E-8 T 29-03-2018 IPR006597 Sel1-like repeat CDC59_RS00145 57c37cff4fccccdf93d7e20d6157a211 252 SMART SM00671 77 112 7.9E-4 T 29-03-2018 IPR006597 Sel1-like repeat CDC59_RS00145 57c37cff4fccccdf93d7e20d6157a211 252 SMART SM00671 113 148 3.7E-5 T 29-03-2018 IPR006597 Sel1-like repeat CDC59_RS00145 57c37cff4fccccdf93d7e20d6157a211 252 SUPERFAMILY SSF81901 47 235 7.24E-41 T 29-03-2018 CDC59_RS09025 055381467134aadb62663f0c94496f27 307 Gene3D G3DSA:1.10.3720.10 3 293 7.0E-45 T 29-03-2018 CDC59_RS09025 055381467134aadb62663f0c94496f27 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 304 5.0E-42 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS09025 055381467134aadb62663f0c94496f27 307 SUPERFAMILY SSF161098 90 288 9.94E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS06940 5bf9d9aa1e8175be7a0e9c6d5dfad2c8 783 SUPERFAMILY SSF101904 526 768 1.26E-45 T 29-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal CDC59_RS06940 5bf9d9aa1e8175be7a0e9c6d5dfad2c8 783 TIGRFAM TIGR01062 parC_Gneg: DNA topoisomerase IV, A subunit 15 711 2.0E-226 T 29-03-2018 CDC59_RS06940 5bf9d9aa1e8175be7a0e9c6d5dfad2c8 783 Gene3D G3DSA:2.120.10.90 519 772 3.5E-45 T 29-03-2018 CDC59_RS06940 5bf9d9aa1e8175be7a0e9c6d5dfad2c8 783 Gene3D G3DSA:1.10.268.10 372 511 6.6E-41 T 29-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDC59_RS06940 5bf9d9aa1e8175be7a0e9c6d5dfad2c8 783 SMART SM00434 17 489 3.2E-214 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDC59_RS06940 5bf9d9aa1e8175be7a0e9c6d5dfad2c8 783 SUPERFAMILY SSF56719 37 511 3.14E-149 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CDC59_RS06940 5bf9d9aa1e8175be7a0e9c6d5dfad2c8 783 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 38 488 4.9E-132 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDC59_RS06940 5bf9d9aa1e8175be7a0e9c6d5dfad2c8 783 Gene3D G3DSA:3.90.199.10 40 293 1.5E-111 T 29-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 CDC59_RS06940 5bf9d9aa1e8175be7a0e9c6d5dfad2c8 783 Hamap MF_00936 DNA topoisomerase 4 subunit A [parC]. 10 773 32.956 T 29-03-2018 IPR005742 DNA topoisomerase IV, subunit A, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CDC59_RS06940 5bf9d9aa1e8175be7a0e9c6d5dfad2c8 783 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 678 718 4.5E-7 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CDC59_RS13505 c7eeba06638a83b571d0e9b807848502 298 Gene3D G3DSA:2.60.120.10 9 271 5.8E-87 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CDC59_RS13505 c7eeba06638a83b571d0e9b807848502 298 Pfam PF02678 Pirin 30 130 1.6E-36 T 29-03-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 CDC59_RS13505 c7eeba06638a83b571d0e9b807848502 298 PIRSF PIRSF006232 11 298 6.0E-105 T 29-03-2018 IPR012093 Pirin Reactome: R-HSA-8935690 CDC59_RS13505 c7eeba06638a83b571d0e9b807848502 298 SUPERFAMILY SSF51182 14 297 2.14E-90 T 29-03-2018 IPR011051 RmlC-like cupin domain CDC59_RS13505 c7eeba06638a83b571d0e9b807848502 298 Pfam PF05726 Pirin C-terminal cupin domain 185 298 1.0E-33 T 29-03-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 CDC59_RS22720 0e2d1fd94fbea3db2a6fcb26f0d43536 198 Pfam PF02581 Thiamine monophosphate synthase 10 189 3.1E-45 T 29-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CDC59_RS22720 0e2d1fd94fbea3db2a6fcb26f0d43536 198 Gene3D G3DSA:3.20.20.70 1 198 1.1E-35 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS22720 0e2d1fd94fbea3db2a6fcb26f0d43536 198 SUPERFAMILY SSF51391 4 193 8.24E-51 T 29-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CDC59_RS10410 6ad97c62d5de461ba5bd332d7da504d7 248 TIGRFAM TIGR00667 aat: leucyl/phenylalanyl-tRNA--protein transferase 36 224 2.1E-54 T 29-03-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 CDC59_RS10410 6ad97c62d5de461ba5bd332d7da504d7 248 Hamap MF_00688 Leucyl/phenylalanyl-tRNA--protein transferase [aat]. 1 248 95.615 T 29-03-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 CDC59_RS10410 6ad97c62d5de461ba5bd332d7da504d7 248 SUPERFAMILY SSF55729 2 231 4.93E-83 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDC59_RS10410 6ad97c62d5de461ba5bd332d7da504d7 248 Pfam PF03588 Leucyl/phenylalanyl-tRNA protein transferase 36 210 4.7E-69 T 29-03-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 CDC59_RS06890 ac765385d4aea8754abdf3ee82ed74d5 496 Pfam PF00654 Voltage gated chloride channel 112 464 9.9E-69 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CDC59_RS06890 ac765385d4aea8754abdf3ee82ed74d5 496 SUPERFAMILY SSF81340 45 481 1.06E-82 T 29-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 CDC59_RS06890 ac765385d4aea8754abdf3ee82ed74d5 496 Gene3D G3DSA:1.10.3080.10 45 485 2.6E-68 T 29-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 CDC59_RS06890 ac765385d4aea8754abdf3ee82ed74d5 496 PRINTS PR00762 Chloride channel signature 432 451 3.9E-19 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CDC59_RS06890 ac765385d4aea8754abdf3ee82ed74d5 496 PRINTS PR00762 Chloride channel signature 214 233 3.9E-19 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CDC59_RS06890 ac765385d4aea8754abdf3ee82ed74d5 496 PRINTS PR00762 Chloride channel signature 123 140 3.9E-19 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CDC59_RS06890 ac765385d4aea8754abdf3ee82ed74d5 496 PRINTS PR00762 Chloride channel signature 382 402 3.9E-19 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CDC59_RS06890 ac765385d4aea8754abdf3ee82ed74d5 496 PRINTS PR00762 Chloride channel signature 414 430 3.9E-19 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CDC59_RS14350 baf0c40d7675f45655447afcf5dbbfed 377 Gene3D G3DSA:1.20.120.140 3 167 1.1E-17 T 29-03-2018 CDC59_RS14350 baf0c40d7675f45655447afcf5dbbfed 377 Pfam PF00448 SRP54-type protein, GTPase domain 177 377 7.8E-71 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CDC59_RS14350 baf0c40d7675f45655447afcf5dbbfed 377 SMART SM00382 176 355 3.1E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS14350 baf0c40d7675f45655447afcf5dbbfed 377 Pfam PF02881 SRP54-type protein, helical bundle domain 96 158 2.1E-11 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CDC59_RS14350 baf0c40d7675f45655447afcf5dbbfed 377 SMART SM00963 87 163 2.5E-17 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CDC59_RS14350 baf0c40d7675f45655447afcf5dbbfed 377 SUPERFAMILY SSF52540 175 376 1.81E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS14350 baf0c40d7675f45655447afcf5dbbfed 377 SMART SM00962 177 377 1.0E-108 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CDC59_RS14350 baf0c40d7675f45655447afcf5dbbfed 377 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 106 376 4.9E-101 T 29-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 CDC59_RS14350 baf0c40d7675f45655447afcf5dbbfed 377 Gene3D G3DSA:3.40.50.300 175 377 2.8E-36 T 29-03-2018 CDC59_RS14350 baf0c40d7675f45655447afcf5dbbfed 377 SUPERFAMILY SSF47364 82 157 4.19E-18 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CDC59_RS14350 baf0c40d7675f45655447afcf5dbbfed 377 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 106 377 59.027 T 29-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 CDC59_RS14350 baf0c40d7675f45655447afcf5dbbfed 377 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 350 363 - T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CDC59_RS02920 eb4f4a119c81c174580f46127cb458f5 514 Gene3D G3DSA:3.60.120.10 13 504 3.5E-164 T 29-03-2018 IPR005801 ADC synthase GO:0009058 CDC59_RS02920 eb4f4a119c81c174580f46127cb458f5 514 Pfam PF04715 Anthranilate synthase component I, N terminal region 26 172 2.7E-36 T 29-03-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CDC59_RS02920 eb4f4a119c81c174580f46127cb458f5 514 Pfam PF00425 chorismate binding enzyme 221 494 2.8E-92 T 29-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal CDC59_RS02920 eb4f4a119c81c174580f46127cb458f5 514 PRINTS PR00095 Anthranilate synthase component I signature 356 369 5.4E-24 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CDC59_RS02920 eb4f4a119c81c174580f46127cb458f5 514 PRINTS PR00095 Anthranilate synthase component I signature 342 355 5.4E-24 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CDC59_RS02920 eb4f4a119c81c174580f46127cb458f5 514 PRINTS PR00095 Anthranilate synthase component I signature 436 450 5.4E-24 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CDC59_RS02920 eb4f4a119c81c174580f46127cb458f5 514 PRINTS PR00095 Anthranilate synthase component I signature 451 465 5.4E-24 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CDC59_RS02920 eb4f4a119c81c174580f46127cb458f5 514 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 25 502 3.8E-162 T 29-03-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CDC59_RS02920 eb4f4a119c81c174580f46127cb458f5 514 SUPERFAMILY SSF56322 14 502 9.94E-155 T 29-03-2018 IPR005801 ADC synthase GO:0009058 CDC59_RS23000 68558c1b5eaffb984f4fc58647fd3caa 477 Pfam PF00149 Calcineurin-like phosphoesterase 52 334 3.3E-10 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CDC59_RS23000 68558c1b5eaffb984f4fc58647fd3caa 477 PIRSF PIRSF036767 12 477 2.4E-191 T 29-03-2018 IPR017064 Acid sphingomyelinase-like phosphodiesterase, predicted GO:0004767|GO:0005615|GO:0006685 CDC59_RS23000 68558c1b5eaffb984f4fc58647fd3caa 477 SUPERFAMILY SSF56300 50 376 1.56E-26 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CDC59_RS23000 68558c1b5eaffb984f4fc58647fd3caa 477 Gene3D G3DSA:3.60.21.10 50 384 1.2E-24 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CDC59_RS17685 09aae3c3beb7df78f63c629c98def5c4 301 SUPERFAMILY SSF53850 90 294 2.48E-37 T 29-03-2018 CDC59_RS17685 09aae3c3beb7df78f63c629c98def5c4 301 Pfam PF03466 LysR substrate binding domain 97 294 2.7E-17 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS17685 09aae3c3beb7df78f63c629c98def5c4 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 1.7E-15 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS17685 09aae3c3beb7df78f63c629c98def5c4 301 Gene3D G3DSA:3.40.190.10 217 301 2.3E-4 T 29-03-2018 CDC59_RS17685 09aae3c3beb7df78f63c629c98def5c4 301 Gene3D G3DSA:3.40.190.10 83 216 8.5E-22 T 29-03-2018 CDC59_RS17685 09aae3c3beb7df78f63c629c98def5c4 301 Gene3D G3DSA:1.10.10.10 1 82 8.7E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS17685 09aae3c3beb7df78f63c629c98def5c4 301 SUPERFAMILY SSF46785 3 85 1.9E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS17955 a54943a5147ebbcf4598d047026cb40d 226 SUPERFAMILY SSF51182 122 221 2.51E-14 T 29-03-2018 IPR011051 RmlC-like cupin domain CDC59_RS17955 a54943a5147ebbcf4598d047026cb40d 226 Gene3D G3DSA:2.60.120.10 3 126 5.7E-22 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CDC59_RS17955 a54943a5147ebbcf4598d047026cb40d 226 Pfam PF12973 ChrR Cupin-like domain 19 109 5.3E-37 T 29-03-2018 IPR025979 ChrR-like cupin domain CDC59_RS17955 a54943a5147ebbcf4598d047026cb40d 226 Pfam PF12973 ChrR Cupin-like domain 133 212 3.7E-8 T 29-03-2018 IPR025979 ChrR-like cupin domain CDC59_RS17955 a54943a5147ebbcf4598d047026cb40d 226 SUPERFAMILY SSF51182 4 124 1.17E-32 T 29-03-2018 IPR011051 RmlC-like cupin domain CDC59_RS17730 6367cf35601caf3947210d583170487c 492 Gene3D G3DSA:3.40.605.10 14 276 4.8E-86 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CDC59_RS17730 6367cf35601caf3947210d583170487c 492 Pfam PF00171 Aldehyde dehydrogenase family 24 481 1.8E-152 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CDC59_RS17730 6367cf35601caf3947210d583170487c 492 Gene3D G3DSA:3.40.309.10 277 466 3.2E-61 T 29-03-2018 CDC59_RS17730 6367cf35601caf3947210d583170487c 492 SUPERFAMILY SSF53720 15 483 4.84E-148 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CDC59_RS14525 bde2f75849c2f32fdc662b9146747e27 159 Pfam PF00210 Ferritin-like domain 8 144 3.3E-39 T 29-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 CDC59_RS14525 bde2f75849c2f32fdc662b9146747e27 159 Gene3D G3DSA:1.20.1260.10 1 78 3.8E-17 T 29-03-2018 IPR012347 Ferritin-related CDC59_RS14525 bde2f75849c2f32fdc662b9146747e27 159 Gene3D G3DSA:1.20.5.420 85 138 1.6E-24 T 29-03-2018 CDC59_RS14525 bde2f75849c2f32fdc662b9146747e27 159 PRINTS PR00601 Bacterioferritin signature 23 43 9.9E-69 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CDC59_RS14525 bde2f75849c2f32fdc662b9146747e27 159 PRINTS PR00601 Bacterioferritin signature 65 85 9.9E-69 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CDC59_RS14525 bde2f75849c2f32fdc662b9146747e27 159 PRINTS PR00601 Bacterioferritin signature 107 127 9.9E-69 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CDC59_RS14525 bde2f75849c2f32fdc662b9146747e27 159 PRINTS PR00601 Bacterioferritin signature 128 149 9.9E-69 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CDC59_RS14525 bde2f75849c2f32fdc662b9146747e27 159 PRINTS PR00601 Bacterioferritin signature 86 106 9.9E-69 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CDC59_RS14525 bde2f75849c2f32fdc662b9146747e27 159 PRINTS PR00601 Bacterioferritin signature 3 22 9.9E-69 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CDC59_RS14525 bde2f75849c2f32fdc662b9146747e27 159 PRINTS PR00601 Bacterioferritin signature 44 64 9.9E-69 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CDC59_RS14525 bde2f75849c2f32fdc662b9146747e27 159 PIRSF PIRSF002560 1 157 7.0E-74 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CDC59_RS14525 bde2f75849c2f32fdc662b9146747e27 159 TIGRFAM TIGR00754 bfr: bacterioferritin 1 155 3.9E-76 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CDC59_RS14525 bde2f75849c2f32fdc662b9146747e27 159 SUPERFAMILY SSF47240 1 157 4.17E-56 T 29-03-2018 IPR009078 Ferritin-like superfamily CDC59_RS14525 bde2f75849c2f32fdc662b9146747e27 159 ProSitePatterns PS00549 Bacterioferritin signature. 1 19 - T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CDC59_RS15585 7072297cb9e89189f7e8c0411e0edaf1 182 Gene3D G3DSA:3.90.1340.10 2 54 1.6E-18 T 29-03-2018 IPR011083 Phage tail collar domain CDC59_RS15585 7072297cb9e89189f7e8c0411e0edaf1 182 SUPERFAMILY SSF88874 3 176 9.42E-43 T 29-03-2018 CDC59_RS15585 7072297cb9e89189f7e8c0411e0edaf1 182 Gene3D G3DSA:4.10.1070.10 55 165 1.0E-4 T 29-03-2018 CDC59_RS15585 7072297cb9e89189f7e8c0411e0edaf1 182 Pfam PF07484 Phage Tail Collar Domain 6 62 3.5E-24 T 29-03-2018 IPR011083 Phage tail collar domain CDC59_RS14015 6c21ab91b07cb747b046e11239133b4e 277 Pfam PF14819 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term 15 126 2.7E-48 T 29-03-2018 IPR029139 NADPH-dependent 7-cyano-7-deazaguanine reductase, N-terminal KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 CDC59_RS14015 6c21ab91b07cb747b046e11239133b4e 277 Hamap MF_00817 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 277 159.529 T 29-03-2018 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 CDC59_RS14015 6c21ab91b07cb747b046e11239133b4e 277 TIGRFAM TIGR03138 QueF: queuine synthase 4 277 6.2E-125 T 29-03-2018 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 CDC59_RS14015 6c21ab91b07cb747b046e11239133b4e 277 PIRSF PIRSF004750 1 277 1.5E-128 T 29-03-2018 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 CDC59_RS14015 6c21ab91b07cb747b046e11239133b4e 277 Pfam PF14489 QueF-like protein 190 263 1.5E-26 T 29-03-2018 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 CDC59_RS14015 6c21ab91b07cb747b046e11239133b4e 277 Gene3D G3DSA:3.30.1130.10 15 131 1.3E-41 T 29-03-2018 CDC59_RS14015 6c21ab91b07cb747b046e11239133b4e 277 Gene3D G3DSA:3.30.1130.10 139 277 1.3E-45 T 29-03-2018 CDC59_RS14015 6c21ab91b07cb747b046e11239133b4e 277 SUPERFAMILY SSF55620 180 262 3.41E-8 T 29-03-2018 CDC59_RS21430 856ada5d971dde70aac4c9fcb9d0a059 263 Pfam PF11180 Protein of unknown function (DUF2968) 82 254 5.8E-70 T 29-03-2018 IPR021350 Protein of unknown function DUF2968 CDC59_RS21430 856ada5d971dde70aac4c9fcb9d0a059 263 Gene3D G3DSA:1.20.5.170 155 254 9.0E-6 T 29-03-2018 CDC59_RS20175 c607cc432c74b53c26b8c83d1ee5e538 86 Pfam PF01313 Bacterial export proteins, family 3 6 77 1.2E-18 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CDC59_RS20175 c607cc432c74b53c26b8c83d1ee5e538 86 TIGRFAM TIGR01403 fliQ_rel_III: type III secretion protein, HrpO family 5 84 1.4E-30 T 29-03-2018 IPR006306 Type III secretion protein HrpO GO:0006810|GO:0016021 CDC59_RS20175 c607cc432c74b53c26b8c83d1ee5e538 86 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 5.4E-18 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CDC59_RS20175 c607cc432c74b53c26b8c83d1ee5e538 86 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 5.4E-18 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CDC59_RS20175 c607cc432c74b53c26b8c83d1ee5e538 86 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 5.4E-18 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CDC59_RS15330 8d535072fc95454e9d2720fe2fb264c9 482 Gene3D G3DSA:1.20.1600.10 22 482 1.3E-104 T 29-03-2018 CDC59_RS15330 8d535072fc95454e9d2720fe2fb264c9 482 SUPERFAMILY SSF56954 70 482 8.89E-109 T 29-03-2018 CDC59_RS15330 8d535072fc95454e9d2720fe2fb264c9 482 SUPERFAMILY SSF56954 5 34 8.89E-109 T 29-03-2018 CDC59_RS15330 8d535072fc95454e9d2720fe2fb264c9 482 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 14 481 7.9E-130 T 29-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 CDC59_RS15330 8d535072fc95454e9d2720fe2fb264c9 482 Pfam PF02321 Outer membrane efflux protein 79 270 5.9E-28 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CDC59_RS15330 8d535072fc95454e9d2720fe2fb264c9 482 Pfam PF02321 Outer membrane efflux protein 297 479 1.4E-29 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CDC59_RS14185 b0879ebfd550cefa3bdda98eb4c13212 197 Gene3D G3DSA:3.40.50.2020 19 196 6.3E-38 T 29-03-2018 CDC59_RS14185 b0879ebfd550cefa3bdda98eb4c13212 197 SUPERFAMILY SSF53271 26 194 2.88E-49 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CDC59_RS14185 b0879ebfd550cefa3bdda98eb4c13212 197 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 25 192 2.4E-62 T 29-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 CDC59_RS14185 b0879ebfd550cefa3bdda98eb4c13212 197 Pfam PF00156 Phosphoribosyl transferase domain 72 173 4.4E-14 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CDC59_RS14185 b0879ebfd550cefa3bdda98eb4c13212 197 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 25 194 37.184 T 29-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 CDC59_RS04520 c63ba12ab0f19cdbe6d625151eadb5ce 438 SUPERFAMILY SSF53756 60 431 1.02E-14 T 29-03-2018 CDC59_RS04520 c63ba12ab0f19cdbe6d625151eadb5ce 438 Pfam PF00534 Glycosyl transferases group 1 320 412 1.4E-7 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CDC59_RS04520 c63ba12ab0f19cdbe6d625151eadb5ce 438 Gene3D G3DSA:3.40.50.2000 225 419 4.4E-16 T 29-03-2018 CDC59_RS04520 c63ba12ab0f19cdbe6d625151eadb5ce 438 Pfam PF04413 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) 34 214 3.0E-61 T 29-03-2018 IPR007507 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 CDC59_RS20355 02dc2ddf88e71543c8e2203a235a0843 318 SUPERFAMILY SSF51735 6 313 2.76E-57 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS20355 02dc2ddf88e71543c8e2203a235a0843 318 Gene3D G3DSA:3.40.50.720 5 313 3.8E-44 T 29-03-2018 CDC59_RS20355 02dc2ddf88e71543c8e2203a235a0843 318 Pfam PF01370 NAD dependent epimerase/dehydratase family 8 244 8.3E-26 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CDC59_RS03675 ca15d277a6cdaa8b8855cf4d5c370189 168 SUPERFAMILY SSF55811 5 148 9.61E-25 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CDC59_RS03675 ca15d277a6cdaa8b8855cf4d5c370189 168 Pfam PF00293 NUDIX domain 9 121 4.2E-12 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CDC59_RS03675 ca15d277a6cdaa8b8855cf4d5c370189 168 Gene3D G3DSA:3.90.79.10 3 157 9.5E-26 T 29-03-2018 CDC59_RS21605 304c1a979397237a25e85de229aac5d8 360 Gene3D G3DSA:3.40.50.1820 31 338 3.3E-45 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS21605 304c1a979397237a25e85de229aac5d8 360 SUPERFAMILY SSF53474 32 335 6.37E-56 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS21605 304c1a979397237a25e85de229aac5d8 360 Pfam PF07859 alpha/beta hydrolase fold 108 312 2.4E-54 T 29-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CDC59_RS17550 499f64bb5c2a5f7d3457fafcb0aee13f 264 Pfam PF01925 Sulfite exporter TauE/SafE 13 260 2.0E-43 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CDC59_RS04260 8f060d18e297fb6ae68291b8dec90dc3 308 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 53 60 - T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CDC59_RS04260 8f060d18e297fb6ae68291b8dec90dc3 308 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 8 304 1.8E-107 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CDC59_RS04260 8f060d18e297fb6ae68291b8dec90dc3 308 SUPERFAMILY SSF53671 6 304 1.57E-103 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CDC59_RS04260 8f060d18e297fb6ae68291b8dec90dc3 308 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 8 148 9.4E-50 T 29-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 CDC59_RS04260 8f060d18e297fb6ae68291b8dec90dc3 308 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 154 302 3.9E-49 T 29-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 CDC59_RS04260 8f060d18e297fb6ae68291b8dec90dc3 308 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 7 305 76.007 T 29-03-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 CDC59_RS04260 8f060d18e297fb6ae68291b8dec90dc3 308 Gene3D G3DSA:3.40.50.1370 6 164 2.8E-62 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CDC59_RS04260 8f060d18e297fb6ae68291b8dec90dc3 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 269 292 6.7E-26 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CDC59_RS04260 8f060d18e297fb6ae68291b8dec90dc3 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 257 266 6.7E-26 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CDC59_RS04260 8f060d18e297fb6ae68291b8dec90dc3 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 6.7E-26 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CDC59_RS04260 8f060d18e297fb6ae68291b8dec90dc3 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 53 72 6.7E-26 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CDC59_RS04260 8f060d18e297fb6ae68291b8dec90dc3 308 Gene3D G3DSA:3.40.50.1370 165 306 7.4E-49 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CDC59_RS04260 8f060d18e297fb6ae68291b8dec90dc3 308 PRINTS PR00102 Ornithine carbamoyltransferase signature 283 294 5.4E-29 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CDC59_RS04260 8f060d18e297fb6ae68291b8dec90dc3 308 PRINTS PR00102 Ornithine carbamoyltransferase signature 84 97 5.4E-29 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CDC59_RS04260 8f060d18e297fb6ae68291b8dec90dc3 308 PRINTS PR00102 Ornithine carbamoyltransferase signature 51 65 5.4E-29 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CDC59_RS04260 8f060d18e297fb6ae68291b8dec90dc3 308 PRINTS PR00102 Ornithine carbamoyltransferase signature 124 138 5.4E-29 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CDC59_RS04260 8f060d18e297fb6ae68291b8dec90dc3 308 PRINTS PR00102 Ornithine carbamoyltransferase signature 221 231 5.4E-29 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CDC59_RS06535 a7644408d90f9d6fcf032db3cf8c8e06 320 Gene3D G3DSA:3.20.20.370 2 314 1.3E-61 T 29-03-2018 CDC59_RS06535 a7644408d90f9d6fcf032db3cf8c8e06 320 Pfam PF01522 Polysaccharide deacetylase 76 164 1.1E-11 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CDC59_RS06535 a7644408d90f9d6fcf032db3cf8c8e06 320 SUPERFAMILY SSF88713 5 310 7.23E-90 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CDC59_RS06535 a7644408d90f9d6fcf032db3cf8c8e06 320 TIGRFAM TIGR03212 uraD_N-term-dom: putative urate catabolism protein 6 310 4.0E-159 T 29-03-2018 IPR017625 PuuE allantoinase/chitin deacetylase 1 CDC59_RS00700 4a1dd60f12907a43f4e720c97ac1bb53 555 SUPERFAMILY SSF51905 472 532 1.04E-88 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS00700 4a1dd60f12907a43f4e720c97ac1bb53 555 SUPERFAMILY SSF51905 3 288 1.04E-88 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS00700 4a1dd60f12907a43f4e720c97ac1bb53 555 Pfam PF05199 GMC oxidoreductase 387 525 4.0E-42 T 29-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 CDC59_RS00700 4a1dd60f12907a43f4e720c97ac1bb53 555 Pfam PF00732 GMC oxidoreductase 4 295 5.0E-79 T 29-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CDC59_RS00700 4a1dd60f12907a43f4e720c97ac1bb53 555 Gene3D G3DSA:4.10.450.10 35 103 1.9E-29 T 29-03-2018 CDC59_RS00700 4a1dd60f12907a43f4e720c97ac1bb53 555 SUPERFAMILY SSF54373 290 473 2.06E-63 T 29-03-2018 CDC59_RS00700 4a1dd60f12907a43f4e720c97ac1bb53 555 PIRSF PIRSF000137 1 539 1.5E-151 T 29-03-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CDC59_RS00700 4a1dd60f12907a43f4e720c97ac1bb53 555 Gene3D G3DSA:3.30.560.10 104 488 1.5E-104 T 29-03-2018 CDC59_RS03150 f801d4da8522dfa1e3258d9dcfe830a1 410 SMART SM00842 9 195 1.5E-107 T 29-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 CDC59_RS03150 f801d4da8522dfa1e3258d9dcfe830a1 410 Gene3D G3DSA:3.30.420.40 257 351 9.1E-20 T 29-03-2018 CDC59_RS03150 f801d4da8522dfa1e3258d9dcfe830a1 410 Gene3D G3DSA:3.30.420.40 196 256 1.5E-8 T 29-03-2018 CDC59_RS03150 f801d4da8522dfa1e3258d9dcfe830a1 410 PIRSF PIRSF003101 1 410 7.4E-151 T 29-03-2018 IPR020823 Cell division protein FtsA GO:0007049 CDC59_RS03150 f801d4da8522dfa1e3258d9dcfe830a1 410 Pfam PF14450 Cell division protein FtsA 206 373 1.7E-25 T 29-03-2018 CDC59_RS03150 f801d4da8522dfa1e3258d9dcfe830a1 410 Pfam PF14450 Cell division protein FtsA 10 192 1.3E-11 T 29-03-2018 CDC59_RS03150 f801d4da8522dfa1e3258d9dcfe830a1 410 Gene3D G3DSA:3.30.420.40 2 185 1.4E-38 T 29-03-2018 CDC59_RS03150 f801d4da8522dfa1e3258d9dcfe830a1 410 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 9 376 8.6E-147 T 29-03-2018 IPR020823 Cell division protein FtsA GO:0007049 CDC59_RS03150 f801d4da8522dfa1e3258d9dcfe830a1 410 Pfam PF02491 SHS2 domain inserted in FTSA 84 161 1.5E-32 T 29-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 CDC59_RS03150 f801d4da8522dfa1e3258d9dcfe830a1 410 Hamap MF_02033 Cell division protein FtsA [ftsA]. 5 410 31.207 T 29-03-2018 IPR020823 Cell division protein FtsA GO:0007049 CDC59_RS03150 f801d4da8522dfa1e3258d9dcfe830a1 410 SUPERFAMILY SSF53067 197 375 3.16E-48 T 29-03-2018 CDC59_RS03150 f801d4da8522dfa1e3258d9dcfe830a1 410 SUPERFAMILY SSF53067 7 196 2.75E-63 T 29-03-2018 CDC59_RS22855 ae4e5fbc06afa0ae81e38f7ce36e0ccc 302 Gene3D G3DSA:1.10.10.10 7 88 4.0E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS22855 ae4e5fbc06afa0ae81e38f7ce36e0ccc 302 Pfam PF03466 LysR substrate binding domain 98 287 2.5E-20 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS22855 ae4e5fbc06afa0ae81e38f7ce36e0ccc 302 SUPERFAMILY SSF53850 99 290 3.44E-21 T 29-03-2018 CDC59_RS22855 ae4e5fbc06afa0ae81e38f7ce36e0ccc 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 13 72 8.9E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS22855 ae4e5fbc06afa0ae81e38f7ce36e0ccc 302 Gene3D G3DSA:3.40.190.10 89 283 3.5E-16 T 29-03-2018 CDC59_RS22855 ae4e5fbc06afa0ae81e38f7ce36e0ccc 302 SUPERFAMILY SSF46785 12 113 1.34E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS13600 9ebee7c38e3d8ddd2e361bd7d02a581b 325 Gene3D G3DSA:1.20.58.180 219 308 5.3E-31 T 29-03-2018 CDC59_RS13600 9ebee7c38e3d8ddd2e361bd7d02a581b 325 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 4 306 1.1E-143 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CDC59_RS13600 9ebee7c38e3d8ddd2e361bd7d02a581b 325 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 3 313 2.5E-148 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CDC59_RS13600 9ebee7c38e3d8ddd2e361bd7d02a581b 325 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 108 132 1.5E-57 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CDC59_RS13600 9ebee7c38e3d8ddd2e361bd7d02a581b 325 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 56 71 1.5E-57 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CDC59_RS13600 9ebee7c38e3d8ddd2e361bd7d02a581b 325 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 134 154 1.5E-57 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CDC59_RS13600 9ebee7c38e3d8ddd2e361bd7d02a581b 325 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 157 172 1.5E-57 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CDC59_RS13600 9ebee7c38e3d8ddd2e361bd7d02a581b 325 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 77 97 1.5E-57 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CDC59_RS13600 9ebee7c38e3d8ddd2e361bd7d02a581b 325 Gene3D G3DSA:3.30.930.10 1 217 2.2E-86 T 29-03-2018 CDC59_RS13600 9ebee7c38e3d8ddd2e361bd7d02a581b 325 SUPERFAMILY SSF55681 3 306 2.24E-124 T 29-03-2018 CDC59_RS13600 9ebee7c38e3d8ddd2e361bd7d02a581b 325 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 2 307 60.188 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CDC59_RS04745 c359402a7add7633fdd8c4b821728534 434 TIGRFAM TIGR02800 propeller_TolB: Tol-Pal system beta propeller repeat protein TolB 24 430 1.8E-156 T 29-03-2018 IPR014167 Tol-Pal system beta propeller repeat-containing protein, TolB GO:0017038|GO:0042597 CDC59_RS04745 c359402a7add7633fdd8c4b821728534 434 Pfam PF04052 TolB amino-terminal domain 33 131 7.8E-25 T 29-03-2018 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 CDC59_RS04745 c359402a7add7633fdd8c4b821728534 434 Pfam PF07676 WD40-like Beta Propeller Repeat 328 363 8.3E-9 T 29-03-2018 IPR011659 WD40-like Beta Propeller CDC59_RS04745 c359402a7add7633fdd8c4b821728534 434 Pfam PF07676 WD40-like Beta Propeller Repeat 239 271 4.5E-9 T 29-03-2018 IPR011659 WD40-like Beta Propeller CDC59_RS04745 c359402a7add7633fdd8c4b821728534 434 Pfam PF07676 WD40-like Beta Propeller Repeat 374 401 0.041 T 29-03-2018 IPR011659 WD40-like Beta Propeller CDC59_RS04745 c359402a7add7633fdd8c4b821728534 434 Pfam PF07676 WD40-like Beta Propeller Repeat 280 316 5.4E-14 T 29-03-2018 IPR011659 WD40-like Beta Propeller CDC59_RS04745 c359402a7add7633fdd8c4b821728534 434 Pfam PF07676 WD40-like Beta Propeller Repeat 197 228 7.7E-7 T 29-03-2018 IPR011659 WD40-like Beta Propeller CDC59_RS04745 c359402a7add7633fdd8c4b821728534 434 Gene3D G3DSA:2.60.120.20 235 278 5.9E-11 T 29-03-2018 CDC59_RS04745 c359402a7add7633fdd8c4b821728534 434 Gene3D G3DSA:2.60.120.20 279 319 6.0E-15 T 29-03-2018 CDC59_RS04745 c359402a7add7633fdd8c4b821728534 434 Gene3D G3DSA:2.60.120.20 172 234 3.5E-7 T 29-03-2018 CDC59_RS04745 c359402a7add7633fdd8c4b821728534 434 SUPERFAMILY SSF52964 41 164 7.45E-32 T 29-03-2018 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 CDC59_RS04745 c359402a7add7633fdd8c4b821728534 434 Hamap MF_00671 Protein TolB [tolB]. 14 429 34.762 T 29-03-2018 IPR014167 Tol-Pal system beta propeller repeat-containing protein, TolB GO:0017038|GO:0042597 CDC59_RS04745 c359402a7add7633fdd8c4b821728534 434 Gene3D G3DSA:2.130.10.10 320 431 1.2E-14 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CDC59_RS04745 c359402a7add7633fdd8c4b821728534 434 SUPERFAMILY SSF69304 161 431 6.93E-58 T 29-03-2018 CDC59_RS04745 c359402a7add7633fdd8c4b821728534 434 Gene3D G3DSA:3.40.50.10070 32 167 9.2E-30 T 29-03-2018 CDC59_RS17960 ed18b0229b1e874af45a791d19bc8b05 114 SUPERFAMILY SSF69118 2 106 1.57E-26 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CDC59_RS17960 ed18b0229b1e874af45a791d19bc8b05 114 Gene3D G3DSA:1.20.1290.10 6 113 7.4E-22 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CDC59_RS17960 ed18b0229b1e874af45a791d19bc8b05 114 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 41 91 3.0E-17 T 29-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CDC59_RS17960 ed18b0229b1e874af45a791d19bc8b05 114 Pfam PF02627 Carboxymuconolactone decarboxylase family 24 106 3.7E-19 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CDC59_RS00485 d298e6918b9ac944d9fc791206a3668a 376 Pfam PF13609 Gram-negative porin 13 352 1.6E-44 T 29-03-2018 CDC59_RS00485 d298e6918b9ac944d9fc791206a3668a 376 SUPERFAMILY SSF56935 28 376 1.89E-56 T 29-03-2018 CDC59_RS00485 d298e6918b9ac944d9fc791206a3668a 376 Gene3D G3DSA:2.40.160.10 29 376 7.6E-52 T 29-03-2018 CDC59_RS02010 0751612a004b760c4af0f5e60134bdac 137 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 6 129 10.011 T 29-03-2018 IPR022907 VapC family GO:0004540 CDC59_RS02010 0751612a004b760c4af0f5e60134bdac 137 Pfam PF01850 PIN domain 7 116 5.9E-15 T 29-03-2018 IPR002716 PIN domain CDC59_RS02010 0751612a004b760c4af0f5e60134bdac 137 SUPERFAMILY SSF88723 7 130 7.29E-20 T 29-03-2018 IPR029060 PIN domain-like CDC59_RS02010 0751612a004b760c4af0f5e60134bdac 137 Gene3D G3DSA:3.40.50.1010 4 136 2.1E-17 T 29-03-2018 IPR029060 PIN domain-like CDC59_RS08410 afaf18f66cd033efd36bbc90f8670087 169 Gene3D G3DSA:1.20.1170.10 6 169 3.4E-5 T 29-03-2018 CDC59_RS21240 4e359c86512e8b190d3060522cbc6e62 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 1.2E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS21240 4e359c86512e8b190d3060522cbc6e62 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.2E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS21240 4e359c86512e8b190d3060522cbc6e62 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 1.2E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS21240 4e359c86512e8b190d3060522cbc6e62 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.2E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS21240 4e359c86512e8b190d3060522cbc6e62 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.2E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS21240 4e359c86512e8b190d3060522cbc6e62 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 1.2E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS21240 4e359c86512e8b190d3060522cbc6e62 261 Pfam PF00106 short chain dehydrogenase 7 198 1.4E-53 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS21240 4e359c86512e8b190d3060522cbc6e62 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 2.0E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS21240 4e359c86512e8b190d3060522cbc6e62 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 2.0E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS21240 4e359c86512e8b190d3060522cbc6e62 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 2.0E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS21240 4e359c86512e8b190d3060522cbc6e62 261 TIGRFAM TIGR01963 PHB_DH: 3-hydroxybutyrate dehydrogenase 7 261 4.5E-106 T 29-03-2018 IPR011294 3-hydroxybutyrate dehydrogenase GO:0003858|GO:0055114 CDC59_RS21240 4e359c86512e8b190d3060522cbc6e62 261 SUPERFAMILY SSF51735 1 260 8.24E-74 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS21240 4e359c86512e8b190d3060522cbc6e62 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CDC59_RS21240 4e359c86512e8b190d3060522cbc6e62 261 Gene3D G3DSA:3.40.50.720 1 261 8.0E-66 T 29-03-2018 CDC59_RS08785 c31a40e8e0b11f42190a1b78e2f7cb89 85 Pfam PF02597 ThiS family 6 85 3.0E-18 T 29-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 CDC59_RS08785 c31a40e8e0b11f42190a1b78e2f7cb89 85 TIGRFAM TIGR01682 moaD: molybdopterin converting factor, subunit 1 3 85 1.6E-27 T 29-03-2018 IPR010034 Molybdopterin converting factor, subunit 1 GO:0006777 Reactome: R-HSA-947581 CDC59_RS08785 c31a40e8e0b11f42190a1b78e2f7cb89 85 SUPERFAMILY SSF54285 1 83 2.24E-20 T 29-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CDC59_RS08785 c31a40e8e0b11f42190a1b78e2f7cb89 85 Gene3D G3DSA:3.10.20.30 3 85 5.6E-19 T 29-03-2018 IPR012675 Beta-grasp domain CDC59_RS03505 94c69c8acdd917c46b1992b3cad0c503 192 PIRSF PIRSF006162 32 192 9.2E-37 T 29-03-2018 IPR026037 Phosphatidylglycerophosphatase A KEGG: 00564+3.1.3.27|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 CDC59_RS03505 94c69c8acdd917c46b1992b3cad0c503 192 Pfam PF04608 Phosphatidylglycerophosphatase A 43 189 1.1E-45 T 29-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 CDC59_RS03505 94c69c8acdd917c46b1992b3cad0c503 192 SUPERFAMILY SSF101307 36 190 7.19E-32 T 29-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 CDC59_RS03505 94c69c8acdd917c46b1992b3cad0c503 192 Gene3D G3DSA:1.10.3760.10 69 192 1.5E-32 T 29-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 CDC59_RS05205 92ceb01ad5019b5355ba76d2f8b83901 111 Pfam PF13272 Putative 2/3 transmembrane domain holin 6 110 1.8E-37 T 29-03-2018 IPR025140 Putative 2/3 transmembrane domain holin CDC59_RS19550 81c680f8efd1e7259de667123d7936f7 268 Gene3D G3DSA:3.40.50.720 1 124 8.6E-13 T 29-03-2018 CDC59_RS19550 81c680f8efd1e7259de667123d7936f7 268 PIRSF PIRSF005227 1 268 1.6E-84 T 29-03-2018 IPR011182 L-aspartate dehydrogenase GO:0009435|GO:0033735|GO:0055114 KEGG: 00760+1.4.1.21 CDC59_RS19550 81c680f8efd1e7259de667123d7936f7 268 SUPERFAMILY SSF51735 1 154 2.87E-19 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS19550 81c680f8efd1e7259de667123d7936f7 268 SUPERFAMILY SSF55347 125 238 1.77E-31 T 29-03-2018 CDC59_RS19550 81c680f8efd1e7259de667123d7936f7 268 Gene3D G3DSA:3.30.360.10 125 237 1.9E-37 T 29-03-2018 CDC59_RS19550 81c680f8efd1e7259de667123d7936f7 268 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 8 120 4.1E-26 T 29-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 CDC59_RS19550 81c680f8efd1e7259de667123d7936f7 268 Hamap MF_01265 Probable L-aspartate dehydrogenase [nadX]. 1 268 37.397 T 29-03-2018 IPR020626 L-aspartate dehydrogenase, prokaryotic GO:0009435|GO:0033735|GO:0055114 KEGG: 00760+1.4.1.21 CDC59_RS19550 81c680f8efd1e7259de667123d7936f7 268 Pfam PF01958 Domain of unknown function DUF108 169 256 1.5E-32 T 29-03-2018 IPR002811 Aspartate dehydrogenase GO:0006742|GO:0016491|GO:0019363|GO:0055114 KEGG: 00760+1.4.1.21 CDC59_RS13250 cdf54ab8f6be46292cbeac04010f6fff 425 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 313 329 5.7E-18 T 29-03-2018 CDC59_RS13250 cdf54ab8f6be46292cbeac04010f6fff 425 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 298 313 5.7E-18 T 29-03-2018 CDC59_RS13250 cdf54ab8f6be46292cbeac04010f6fff 425 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 5.7E-18 T 29-03-2018 CDC59_RS13250 cdf54ab8f6be46292cbeac04010f6fff 425 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 156 171 5.7E-18 T 29-03-2018 CDC59_RS13250 cdf54ab8f6be46292cbeac04010f6fff 425 SUPERFAMILY SSF51905 285 373 6.87E-53 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS13250 cdf54ab8f6be46292cbeac04010f6fff 425 SUPERFAMILY SSF51905 1 177 6.87E-53 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS13250 cdf54ab8f6be46292cbeac04010f6fff 425 SUPERFAMILY SSF54373 182 289 1.69E-30 T 29-03-2018 CDC59_RS13250 cdf54ab8f6be46292cbeac04010f6fff 425 Gene3D G3DSA:3.50.50.60 1 364 1.5E-36 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS13250 cdf54ab8f6be46292cbeac04010f6fff 425 Pfam PF01494 FAD binding domain 2 358 5.0E-19 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 CDC59_RS17865 84ea5b9466789a02a98afb5eb8472774 103 Pfam PF04023 FeoA domain 1 76 3.5E-18 T 29-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CDC59_RS17865 84ea5b9466789a02a98afb5eb8472774 103 SMART SM00899 1 77 1.9E-18 T 29-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CDC59_RS17865 84ea5b9466789a02a98afb5eb8472774 103 Gene3D G3DSA:2.30.30.90 1 86 2.5E-21 T 29-03-2018 CDC59_RS17865 84ea5b9466789a02a98afb5eb8472774 103 SUPERFAMILY SSF50037 6 76 2.15E-13 T 29-03-2018 IPR008988 Transcriptional repressor, C-terminal CDC59_RS03530 c54a451904e4317858c5ea5bd9e42f22 188 Pfam PF06078 Bacterial protein of unknown function (DUF937) 47 182 2.0E-16 T 29-03-2018 IPR009282 Protein of unknown function DUF937 CDC59_RS03530 c54a451904e4317858c5ea5bd9e42f22 188 SUPERFAMILY SSF140804 81 187 9.81E-26 T 29-03-2018 IPR027405 YidB-like CDC59_RS03530 c54a451904e4317858c5ea5bd9e42f22 188 Gene3D G3DSA:1.10.10.690 77 188 1.5E-31 T 29-03-2018 CDC59_RS08535 e0a27787d4329d840c70f2fc912dfb52 242 SUPERFAMILY SSF46785 160 237 4.7E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS08535 e0a27787d4329d840c70f2fc912dfb52 242 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 187 203 5.5E-10 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CDC59_RS08535 e0a27787d4329d840c70f2fc912dfb52 242 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 203 218 5.5E-10 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CDC59_RS08535 e0a27787d4329d840c70f2fc912dfb52 242 Pfam PF00027 Cyclic nucleotide-binding domain 44 127 1.7E-13 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CDC59_RS08535 e0a27787d4329d840c70f2fc912dfb52 242 SUPERFAMILY SSF51206 17 156 2.62E-27 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like CDC59_RS08535 e0a27787d4329d840c70f2fc912dfb52 242 Gene3D G3DSA:2.60.120.10 18 157 8.8E-17 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CDC59_RS08535 e0a27787d4329d840c70f2fc912dfb52 242 SMART SM00419 181 229 1.2E-13 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CDC59_RS08535 e0a27787d4329d840c70f2fc912dfb52 242 SMART SM00100 24 142 2.3E-9 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CDC59_RS08535 e0a27787d4329d840c70f2fc912dfb52 242 Pfam PF13545 Crp-like helix-turn-helix domain 162 235 7.4E-19 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CDC59_RS08535 e0a27787d4329d840c70f2fc912dfb52 242 Gene3D G3DSA:1.10.10.10 158 238 8.8E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS08340 165b4360171d36bf90e48bfd908cce33 620 SUPERFAMILY SSF52467 185 386 2.12E-43 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CDC59_RS08340 165b4360171d36bf90e48bfd908cce33 620 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 224 354 7.8E-33 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CDC59_RS08340 165b4360171d36bf90e48bfd908cce33 620 SUPERFAMILY SSF52518 4 214 2.57E-30 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CDC59_RS08340 165b4360171d36bf90e48bfd908cce33 620 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 421 576 2.2E-34 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CDC59_RS08340 165b4360171d36bf90e48bfd908cce33 620 Gene3D G3DSA:3.40.50.970 376 588 8.1E-35 T 29-03-2018 CDC59_RS08340 165b4360171d36bf90e48bfd908cce33 620 Gene3D G3DSA:3.40.50.1220 225 375 7.3E-42 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CDC59_RS08340 165b4360171d36bf90e48bfd908cce33 620 Gene3D G3DSA:3.40.50.970 2 224 4.4E-43 T 29-03-2018 CDC59_RS08340 165b4360171d36bf90e48bfd908cce33 620 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 10 202 4.7E-40 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CDC59_RS08340 165b4360171d36bf90e48bfd908cce33 620 SUPERFAMILY SSF52518 399 602 2.03E-47 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CDC59_RS08340 165b4360171d36bf90e48bfd908cce33 620 TIGRFAM TIGR04377 myo_inos_iolD: 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase 8 619 1.2E-270 T 29-03-2018 IPR030817 3,5/4-Trihydroxycyclohexa-1,2-dione hydrolase GO:0016823|GO:0019310|GO:0030976 KEGG: 00562+3.7.1.22 CDC59_RS08340 165b4360171d36bf90e48bfd908cce33 620 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 457 476 - T 29-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CDC59_RS08590 3d29f543fe7a61beb0e3439558de69c0 515 SUPERFAMILY SSF56954 26 489 1.29E-95 T 29-03-2018 CDC59_RS08590 3d29f543fe7a61beb0e3439558de69c0 515 Gene3D G3DSA:1.20.1600.10 8 494 3.4E-90 T 29-03-2018 CDC59_RS08590 3d29f543fe7a61beb0e3439558de69c0 515 Pfam PF02321 Outer membrane efflux protein 87 277 2.2E-23 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CDC59_RS08590 3d29f543fe7a61beb0e3439558de69c0 515 Pfam PF02321 Outer membrane efflux protein 310 486 4.4E-23 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CDC59_RS08590 3d29f543fe7a61beb0e3439558de69c0 515 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 32 488 3.2E-168 T 29-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 CDC59_RS23155 309fbf1ba417af19085dfeabf30c4f9e 446 Gene3D G3DSA:3.40.830.10 1 299 1.5E-55 T 29-03-2018 CDC59_RS23155 309fbf1ba417af19085dfeabf30c4f9e 446 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 7 271 1.7E-66 T 29-03-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 CDC59_RS23155 309fbf1ba417af19085dfeabf30c4f9e 446 SUPERFAMILY SSF53213 2 280 6.41E-93 T 29-03-2018 CDC59_RS23155 309fbf1ba417af19085dfeabf30c4f9e 446 Pfam PF07746 Aromatic-ring-opening dioxygenase LigAB, LigA subunit 324 410 1.6E-32 T 29-03-2018 IPR011986 Extradiol ring-cleavage dioxygenase LigAB, LigA subunit CDC59_RS23155 309fbf1ba417af19085dfeabf30c4f9e 446 Gene3D G3DSA:1.10.700.10 301 414 1.8E-37 T 29-03-2018 IPR011986 Extradiol ring-cleavage dioxygenase LigAB, LigA subunit CDC59_RS23155 309fbf1ba417af19085dfeabf30c4f9e 446 SUPERFAMILY SSF48076 296 414 2.09E-45 T 29-03-2018 IPR011986 Extradiol ring-cleavage dioxygenase LigAB, LigA subunit CDC59_RS19890 d758dec4ba2a6e857242178cec346f55 368 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS19890 d758dec4ba2a6e857242178cec346f55 368 TIGRFAM TIGR03265 PhnT2: putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein 14 368 8.8E-147 T 29-03-2018 IPR017666 2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT2 GO:0005524 CDC59_RS19890 d758dec4ba2a6e857242178cec346f55 368 SUPERFAMILY SSF50331 250 343 1.59E-5 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CDC59_RS19890 d758dec4ba2a6e857242178cec346f55 368 Gene3D G3DSA:2.40.50.140 293 349 0.0012 T 29-03-2018 CDC59_RS19890 d758dec4ba2a6e857242178cec346f55 368 Gene3D G3DSA:3.40.50.300 13 282 3.4E-72 T 29-03-2018 CDC59_RS19890 d758dec4ba2a6e857242178cec346f55 368 SMART SM00382 41 224 7.8E-20 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS19890 d758dec4ba2a6e857242178cec346f55 368 Pfam PF00005 ABC transporter 32 174 1.8E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS19890 d758dec4ba2a6e857242178cec346f55 368 Pfam PF08402 TOBE domain 293 339 1.7E-6 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CDC59_RS19890 d758dec4ba2a6e857242178cec346f55 368 SUPERFAMILY SSF52540 17 256 5.73E-85 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS23715 75519539e68b4519ab7164ccbf6d04d9 346 Pfam PF13377 Periplasmic binding protein-like domain 178 341 7.6E-39 T 29-03-2018 CDC59_RS23715 75519539e68b4519ab7164ccbf6d04d9 346 Pfam PF00356 Bacterial regulatory proteins, lacI family 9 54 2.1E-19 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDC59_RS23715 75519539e68b4519ab7164ccbf6d04d9 346 Gene3D G3DSA:1.10.260.40 22 60 3.5E-24 T 29-03-2018 CDC59_RS23715 75519539e68b4519ab7164ccbf6d04d9 346 SUPERFAMILY SSF47413 7 64 1.59E-19 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDC59_RS23715 75519539e68b4519ab7164ccbf6d04d9 346 ProSitePatterns PS00356 LacI-type HTH domain signature. 10 28 - T 29-03-2018 CDC59_RS23715 75519539e68b4519ab7164ccbf6d04d9 346 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 19 29 4.7E-5 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDC59_RS23715 75519539e68b4519ab7164ccbf6d04d9 346 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 9 19 4.7E-5 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDC59_RS23715 75519539e68b4519ab7164ccbf6d04d9 346 Gene3D G3DSA:3.40.50.2300 61 182 4.9E-26 T 29-03-2018 CDC59_RS23715 75519539e68b4519ab7164ccbf6d04d9 346 Gene3D G3DSA:1.10.10.10 1 21 0.0016 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS23715 75519539e68b4519ab7164ccbf6d04d9 346 SUPERFAMILY SSF53822 67 345 4.56E-70 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CDC59_RS23715 75519539e68b4519ab7164ccbf6d04d9 346 Gene3D G3DSA:3.40.50.2300 183 315 5.8E-48 T 29-03-2018 CDC59_RS23715 75519539e68b4519ab7164ccbf6d04d9 346 SMART SM00354 7 77 6.5E-28 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDC59_RS23065 d21f15e0e42f861c307dcaa7ce9568da 328 Pfam PF05598 Transposase domain (DUF772) 51 126 5.1E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS23065 d21f15e0e42f861c307dcaa7ce9568da 328 Pfam PF01609 Transposase DDE domain 138 312 2.4E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS21520 d21f15e0e42f861c307dcaa7ce9568da 328 Pfam PF05598 Transposase domain (DUF772) 51 126 5.1E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS21520 d21f15e0e42f861c307dcaa7ce9568da 328 Pfam PF01609 Transposase DDE domain 138 312 2.4E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS18065 d21f15e0e42f861c307dcaa7ce9568da 328 Pfam PF05598 Transposase domain (DUF772) 51 126 5.1E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS18065 d21f15e0e42f861c307dcaa7ce9568da 328 Pfam PF01609 Transposase DDE domain 138 312 2.4E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS22210 d21f15e0e42f861c307dcaa7ce9568da 328 Pfam PF05598 Transposase domain (DUF772) 51 126 5.1E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS22210 d21f15e0e42f861c307dcaa7ce9568da 328 Pfam PF01609 Transposase DDE domain 138 312 2.4E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS09690 d21f15e0e42f861c307dcaa7ce9568da 328 Pfam PF05598 Transposase domain (DUF772) 51 126 5.1E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS09690 d21f15e0e42f861c307dcaa7ce9568da 328 Pfam PF01609 Transposase DDE domain 138 312 2.4E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS13075 4de26a5ae9b25a54153fdf03c034d012 142 SUPERFAMILY SSF53098 14 90 5.61E-14 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDC59_RS13075 4de26a5ae9b25a54153fdf03c034d012 142 Pfam PF00665 Integrase core domain 23 77 9.2E-10 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CDC59_RS13075 4de26a5ae9b25a54153fdf03c034d012 142 Gene3D G3DSA:3.30.420.10 11 113 5.2E-12 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDC59_RS08125 c033d932274de5be46f8fb6027e739dc 289 SUPERFAMILY SSF56219 5 286 2.75E-31 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CDC59_RS08125 c033d932274de5be46f8fb6027e739dc 289 Gene3D G3DSA:3.60.10.10 4 286 9.5E-31 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CDC59_RS08125 c033d932274de5be46f8fb6027e739dc 289 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 6 278 1.9E-9 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CDC59_RS14165 a8320efb54bf12fcf4b088b41fa5ebfd 954 Gene3D G3DSA:3.40.50.300 628 953 3.0E-53 T 29-03-2018 CDC59_RS14165 a8320efb54bf12fcf4b088b41fa5ebfd 954 Gene3D G3DSA:3.40.50.300 422 627 7.1E-22 T 29-03-2018 CDC59_RS14165 a8320efb54bf12fcf4b088b41fa5ebfd 954 ProSitePatterns PS00211 ABC transporters family signature. 841 855 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS14165 a8320efb54bf12fcf4b088b41fa5ebfd 954 Gene3D G3DSA:3.30.190.20 127 256 7.6E-41 T 29-03-2018 CDC59_RS14165 a8320efb54bf12fcf4b088b41fa5ebfd 954 Gene3D G3DSA:1.10.8.280 294 413 5.9E-36 T 29-03-2018 CDC59_RS14165 a8320efb54bf12fcf4b088b41fa5ebfd 954 ProSitePatterns PS00211 ABC transporters family signature. 499 513 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS14165 a8320efb54bf12fcf4b088b41fa5ebfd 954 Gene3D G3DSA:3.40.50.300 35 110 2.0E-4 T 29-03-2018 CDC59_RS14165 a8320efb54bf12fcf4b088b41fa5ebfd 954 Gene3D G3DSA:3.40.50.300 2 34 8.5E-4 T 29-03-2018 CDC59_RS14165 a8320efb54bf12fcf4b088b41fa5ebfd 954 SUPERFAMILY SSF52540 630 924 1.82E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS14165 a8320efb54bf12fcf4b088b41fa5ebfd 954 SUPERFAMILY SSF52540 1 204 1.81E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS14165 a8320efb54bf12fcf4b088b41fa5ebfd 954 SUPERFAMILY SSF52540 442 581 1.81E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS14165 a8320efb54bf12fcf4b088b41fa5ebfd 954 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 4 936 0.0 T 29-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 CDC59_RS14165 a8320efb54bf12fcf4b088b41fa5ebfd 954 Hamap MF_00205 UvrABC system protein A [uvrA]. 1 951 22.334 T 29-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 CDC59_RS12225 f19352f2e36fbeaaa776d3ddab73bb4e 228 Gene3D G3DSA:3.30.70.20 113 192 2.0E-12 T 29-03-2018 CDC59_RS12225 f19352f2e36fbeaaa776d3ddab73bb4e 228 Gene3D G3DSA:3.30.70.20 20 69 5.2E-8 T 29-03-2018 CDC59_RS12225 f19352f2e36fbeaaa776d3ddab73bb4e 228 Pfam PF13247 4Fe-4S dicluster domain 53 124 2.9E-10 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CDC59_RS12225 f19352f2e36fbeaaa776d3ddab73bb4e 228 PRINTS PR00354 7Fe ferredoxin signature 83 100 1.0E-5 T 29-03-2018 IPR000813 7Fe ferredoxin GO:0009055 CDC59_RS12225 f19352f2e36fbeaaa776d3ddab73bb4e 228 PRINTS PR00354 7Fe ferredoxin signature 56 66 1.0E-5 T 29-03-2018 IPR000813 7Fe ferredoxin GO:0009055 CDC59_RS12225 f19352f2e36fbeaaa776d3ddab73bb4e 228 PRINTS PR00354 7Fe ferredoxin signature 66 76 1.0E-5 T 29-03-2018 IPR000813 7Fe ferredoxin GO:0009055 CDC59_RS12225 f19352f2e36fbeaaa776d3ddab73bb4e 228 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 88 99 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CDC59_RS12225 f19352f2e36fbeaaa776d3ddab73bb4e 228 Gene3D G3DSA:3.30.70.20 70 112 5.7E-19 T 29-03-2018 CDC59_RS12225 f19352f2e36fbeaaa776d3ddab73bb4e 228 SUPERFAMILY SSF54862 1 181 3.03E-50 T 29-03-2018 CDC59_RS12225 f19352f2e36fbeaaa776d3ddab73bb4e 228 Gene3D G3DSA:3.30.70.20 2 19 0.041 T 29-03-2018 CDC59_RS21210 aa389b43e22d03f61a22f482fa79bb89 68 Gene3D G3DSA:2.40.50.140 6 68 1.4E-7 T 29-03-2018 CDC59_RS21210 aa389b43e22d03f61a22f482fa79bb89 68 SUPERFAMILY SSF50249 24 67 6.61E-5 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDC59_RS10905 e860e13eaff193b4c232be28d6937b84 235 Gene3D G3DSA:1.20.58.220 123 232 2.4E-25 T 29-03-2018 CDC59_RS10905 e860e13eaff193b4c232be28d6937b84 235 Gene3D G3DSA:1.20.58.220 2 116 1.5E-26 T 29-03-2018 CDC59_RS10905 e860e13eaff193b4c232be28d6937b84 235 PIRSF PIRSF003107 3 225 1.9E-60 T 29-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 CDC59_RS10905 e860e13eaff193b4c232be28d6937b84 235 SUPERFAMILY SSF109755 8 229 6.17E-67 T 29-03-2018 CDC59_RS10905 e860e13eaff193b4c232be28d6937b84 235 Pfam PF01895 PhoU domain 127 210 1.4E-15 T 29-03-2018 IPR026022 PhoU domain CDC59_RS10905 e860e13eaff193b4c232be28d6937b84 235 Pfam PF01895 PhoU domain 22 109 5.3E-19 T 29-03-2018 IPR026022 PhoU domain CDC59_RS10905 e860e13eaff193b4c232be28d6937b84 235 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 8 220 2.8E-67 T 29-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 CDC59_RS12050 ae2a474a8242b104fbc7922b4a656975 149 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 16 135 1.9E-12 T 29-03-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 CDC59_RS12050 ae2a474a8242b104fbc7922b4a656975 149 Gene3D G3DSA:3.40.50.300 41 65 2.6E-4 T 29-03-2018 CDC59_RS12050 ae2a474a8242b104fbc7922b4a656975 149 Gene3D G3DSA:3.40.50.300 66 144 4.3E-14 T 29-03-2018 CDC59_RS12050 ae2a474a8242b104fbc7922b4a656975 149 SMART SM00382 48 143 3.7E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS12050 ae2a474a8242b104fbc7922b4a656975 149 SUPERFAMILY SSF52540 13 132 3.88E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS02520 ade05091746cec345266dc01a931639b 279 Pfam PF00005 ABC transporter 29 176 3.2E-24 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS02520 ade05091746cec345266dc01a931639b 279 SUPERFAMILY SSF52540 9 239 9.25E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS02520 ade05091746cec345266dc01a931639b 279 SMART SM00382 36 250 4.7E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS02520 ade05091746cec345266dc01a931639b 279 Gene3D G3DSA:3.40.50.300 6 253 1.6E-59 T 29-03-2018 CDC59_RS02520 ade05091746cec345266dc01a931639b 279 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS02340 36fd6242dd5f1cefed23e1d78423951d 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 26.956 T 29-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CDC59_RS02340 36fd6242dd5f1cefed23e1d78423951d 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 1.9E-26 T 29-03-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 CDC59_RS02340 36fd6242dd5f1cefed23e1d78423951d 72 SUPERFAMILY SSF50249 1 70 9.71E-27 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDC59_RS02340 36fd6242dd5f1cefed23e1d78423951d 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 70 2.7E-36 T 29-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CDC59_RS02340 36fd6242dd5f1cefed23e1d78423951d 72 Gene3D G3DSA:2.40.50.140 1 72 4.0E-34 T 29-03-2018 CDC59_RS05800 869bbecca9cc2370738525dd497ed598 259 Gene3D G3DSA:3.40.50.1820 20 258 1.0E-28 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS05800 869bbecca9cc2370738525dd497ed598 259 Pfam PF12697 Alpha/beta hydrolase family 36 249 2.6E-21 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS05800 869bbecca9cc2370738525dd497ed598 259 SUPERFAMILY SSF53474 31 252 1.54E-30 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS16205 3f5355fd35aca8f4f1d705dc9aa479a5 136 SUPERFAMILY SSF54637 3 134 1.24E-35 T 29-03-2018 IPR029069 HotDog domain CDC59_RS16205 3f5355fd35aca8f4f1d705dc9aa479a5 136 Gene3D G3DSA:3.10.129.10 1 136 9.7E-24 T 29-03-2018 CDC59_RS16205 3f5355fd35aca8f4f1d705dc9aa479a5 136 ProSitePatterns PS01328 4-hydroxybenzoyl-CoA thioesterase family active site. 10 27 - T 29-03-2018 IPR008272 4-hydroxybenzoyl-CoA thioesterase, active site GO:0016787 CDC59_RS16205 3f5355fd35aca8f4f1d705dc9aa479a5 136 Pfam PF13279 Thioesterase-like superfamily 12 131 1.5E-6 T 29-03-2018 CDC59_RS20480 c0c3904193cb1c175fa1f114b09c5199 249 Gene3D G3DSA:1.10.3720.10 7 232 6.7E-40 T 29-03-2018 CDC59_RS20480 c0c3904193cb1c175fa1f114b09c5199 249 SUPERFAMILY SSF161098 25 215 4.06E-41 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS20480 c0c3904193cb1c175fa1f114b09c5199 249 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 28 120 4.4E-22 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CDC59_RS20480 c0c3904193cb1c175fa1f114b09c5199 249 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 44 226 1.9E-16 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS08030 16df529b0293b95d1237604c4bc9717c 1177 Pfam PF00580 UvrD/REP helicase N-terminal domain 21 472 2.0E-45 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CDC59_RS08030 16df529b0293b95d1237604c4bc9717c 1177 Gene3D G3DSA:3.40.50.300 13 477 4.2E-47 T 29-03-2018 CDC59_RS08030 16df529b0293b95d1237604c4bc9717c 1177 Gene3D G3DSA:3.90.320.10 920 1154 2.1E-5 T 29-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 CDC59_RS08030 16df529b0293b95d1237604c4bc9717c 1177 Gene3D G3DSA:3.40.50.300 563 919 7.3E-37 T 29-03-2018 CDC59_RS08030 16df529b0293b95d1237604c4bc9717c 1177 Pfam PF13361 UvrD-like helicase C-terminal domain 814 914 1.1E-10 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CDC59_RS08030 16df529b0293b95d1237604c4bc9717c 1177 SUPERFAMILY SSF52540 819 843 2.95E-98 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS08030 16df529b0293b95d1237604c4bc9717c 1177 SUPERFAMILY SSF52540 21 81 2.95E-98 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS08030 16df529b0293b95d1237604c4bc9717c 1177 SUPERFAMILY SSF52540 546 791 2.95E-98 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS08030 16df529b0293b95d1237604c4bc9717c 1177 SUPERFAMILY SSF52540 892 917 2.95E-98 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS08030 16df529b0293b95d1237604c4bc9717c 1177 SUPERFAMILY SSF52540 121 201 2.95E-98 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS08030 16df529b0293b95d1237604c4bc9717c 1177 SUPERFAMILY SSF52540 358 513 2.95E-98 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS08030 16df529b0293b95d1237604c4bc9717c 1177 Pfam PF12705 PD-(D/E)XK nuclease superfamily 1008 1139 1.9E-6 T 29-03-2018 CDC59_RS01275 428a0706569b0512dfde7580a68fd26c 184 Gene3D G3DSA:3.40.50.300 3 173 2.6E-41 T 29-03-2018 CDC59_RS01275 428a0706569b0512dfde7580a68fd26c 184 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 3 175 32.793 T 29-03-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CDC59_RS01275 428a0706569b0512dfde7580a68fd26c 184 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 6 168 1.2E-64 T 29-03-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CDC59_RS01275 428a0706569b0512dfde7580a68fd26c 184 Pfam PF01583 Adenylylsulphate kinase 5 159 1.8E-62 T 29-03-2018 CDC59_RS01275 428a0706569b0512dfde7580a68fd26c 184 SUPERFAMILY SSF52540 4 171 7.91E-33 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS20030 37adbed5e9e648c782dff3f06d641bcc 282 Pfam PF01370 NAD dependent epimerase/dehydratase family 24 182 2.1E-18 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CDC59_RS20030 37adbed5e9e648c782dff3f06d641bcc 282 Gene3D G3DSA:3.40.50.720 21 245 1.7E-34 T 29-03-2018 CDC59_RS20030 37adbed5e9e648c782dff3f06d641bcc 282 SUPERFAMILY SSF51735 22 248 4.28E-39 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS03330 a0da0fb2645713f18c5c6477138f2f17 987 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 292 365 2.8E-21 T 29-03-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CDC59_RS03330 a0da0fb2645713f18c5c6477138f2f17 987 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 752 774 - T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CDC59_RS03330 a0da0fb2645713f18c5c6477138f2f17 987 SUPERFAMILY SSF48168 156 367 6.54E-61 T 29-03-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CDC59_RS03330 a0da0fb2645713f18c5c6477138f2f17 987 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 295 911 4.5E-210 T 29-03-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CDC59_RS03330 a0da0fb2645713f18c5c6477138f2f17 987 SUPERFAMILY SSF51998 843 911 6.41E-180 T 29-03-2018 CDC59_RS03330 a0da0fb2645713f18c5c6477138f2f17 987 SUPERFAMILY SSF51998 368 812 6.41E-180 T 29-03-2018 CDC59_RS03330 a0da0fb2645713f18c5c6477138f2f17 987 Pfam PF03477 ATP cone domain 37 133 1.1E-15 T 29-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 CDC59_RS03330 a0da0fb2645713f18c5c6477138f2f17 987 PRINTS PR01183 Ribonucleotide reductase large chain signature 659 681 5.9E-44 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CDC59_RS03330 a0da0fb2645713f18c5c6477138f2f17 987 PRINTS PR01183 Ribonucleotide reductase large chain signature 444 463 5.9E-44 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CDC59_RS03330 a0da0fb2645713f18c5c6477138f2f17 987 PRINTS PR01183 Ribonucleotide reductase large chain signature 579 590 5.9E-44 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CDC59_RS03330 a0da0fb2645713f18c5c6477138f2f17 987 PRINTS PR01183 Ribonucleotide reductase large chain signature 687 710 5.9E-44 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CDC59_RS03330 a0da0fb2645713f18c5c6477138f2f17 987 PRINTS PR01183 Ribonucleotide reductase large chain signature 763 790 5.9E-44 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CDC59_RS03330 a0da0fb2645713f18c5c6477138f2f17 987 PRINTS PR01183 Ribonucleotide reductase large chain signature 621 644 5.9E-44 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CDC59_RS03330 a0da0fb2645713f18c5c6477138f2f17 987 Pfam PF02867 Ribonucleotide reductase, barrel domain 369 908 4.2E-182 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CDC59_RS03330 a0da0fb2645713f18c5c6477138f2f17 987 Gene3D G3DSA:3.20.70.20 274 915 1.3E-211 T 29-03-2018 CDC59_RS19365 cb9e3e189eded4ed84811226c82349fb 268 Gene3D G3DSA:3.20.20.70 10 263 5.3E-66 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS19365 cb9e3e189eded4ed84811226c82349fb 268 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 2 261 35.209 T 29-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 CDC59_RS19365 cb9e3e189eded4ed84811226c82349fb 268 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 55 73 - T 29-03-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 CDC59_RS19365 cb9e3e189eded4ed84811226c82349fb 268 SUPERFAMILY SSF51366 11 261 8.01E-87 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CDC59_RS19365 cb9e3e189eded4ed84811226c82349fb 268 Pfam PF00218 Indole-3-glycerol phosphate synthase 4 258 2.5E-91 T 29-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 CDC59_RS06635 b6f7cce8acd0380895ed75f5f83d6e9b 346 Pfam PF02625 XdhC and CoxI family 21 79 1.6E-20 T 29-03-2018 IPR003777 XdhC- CoxI CDC59_RS06635 b6f7cce8acd0380895ed75f5f83d6e9b 346 SUPERFAMILY SSF51735 169 270 4.55E-6 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS06635 b6f7cce8acd0380895ed75f5f83d6e9b 346 TIGRFAM TIGR02964 xanthine_xdhC: xanthine dehydrogenase accessory protein XdhC 29 319 4.4E-102 T 29-03-2018 IPR014308 Xanthine dehydrogenase accessory protein XdhC CDC59_RS06635 b6f7cce8acd0380895ed75f5f83d6e9b 346 Pfam PF13478 XdhC Rossmann domain 177 318 3.1E-35 T 29-03-2018 IPR027051 XdhC Rossmann domain CDC59_RS06635 b6f7cce8acd0380895ed75f5f83d6e9b 346 Gene3D G3DSA:3.40.50.20 174 262 8.7E-7 T 29-03-2018 CDC59_RS13580 9d93bea1717ab0e5820ca1c4999a0c73 254 Pfam PF02130 Uncharacterized protein family UPF0054 127 245 8.5E-31 T 29-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CDC59_RS13580 9d93bea1717ab0e5820ca1c4999a0c73 254 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 215 225 - T 29-03-2018 IPR020549 Endoribonuclease YbeY, conserved site CDC59_RS13580 9d93bea1717ab0e5820ca1c4999a0c73 254 SUPERFAMILY SSF55486 130 251 1.64E-39 T 29-03-2018 CDC59_RS13580 9d93bea1717ab0e5820ca1c4999a0c73 254 Gene3D G3DSA:3.40.390.30 103 254 2.4E-41 T 29-03-2018 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 CDC59_RS13580 9d93bea1717ab0e5820ca1c4999a0c73 254 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 105 249 21.322 T 29-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CDC59_RS13580 9d93bea1717ab0e5820ca1c4999a0c73 254 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 143 246 1.5E-33 T 29-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CDC59_RS22775 63325402fea7c9de6dc074d555dd62c1 609 TIGRFAM TIGR01196 edd: phosphogluconate dehydratase 7 603 1.4E-304 T 29-03-2018 IPR004786 6-phosphogluconate dehydratase GO:0004456|GO:0009255 KEGG: 00030+4.2.1.12 CDC59_RS22775 63325402fea7c9de6dc074d555dd62c1 609 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 156 166 - T 29-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CDC59_RS22775 63325402fea7c9de6dc074d555dd62c1 609 SUPERFAMILY SSF52016 421 604 1.65E-60 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CDC59_RS22775 63325402fea7c9de6dc074d555dd62c1 609 SUPERFAMILY SSF143975 3 420 2.35E-149 T 29-03-2018 CDC59_RS22775 63325402fea7c9de6dc074d555dd62c1 609 Pfam PF00920 Dehydratase family 67 600 4.6E-169 T 29-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CDC59_RS22775 63325402fea7c9de6dc074d555dd62c1 609 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 507 518 - T 29-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CDC59_RS15295 9383d5adcae8c52d7dad3a9288fd6620 313 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 305 1.7E-60 T 29-03-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CDC59_RS15295 9383d5adcae8c52d7dad3a9288fd6620 313 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 180 302 3.7E-20 T 29-03-2018 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CDC59_RS15295 9383d5adcae8c52d7dad3a9288fd6620 313 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 153 3.1E-37 T 29-03-2018 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CDC59_RS15295 9383d5adcae8c52d7dad3a9288fd6620 313 Gene3D G3DSA:3.40.50.720 1 179 2.0E-28 T 29-03-2018 CDC59_RS15295 9383d5adcae8c52d7dad3a9288fd6620 313 Gene3D G3DSA:1.10.1040.10 180 313 3.1E-25 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CDC59_RS15295 9383d5adcae8c52d7dad3a9288fd6620 313 SUPERFAMILY SSF51735 1 136 3.07E-12 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS15295 9383d5adcae8c52d7dad3a9288fd6620 313 SUPERFAMILY SSF48179 180 304 1.84E-25 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CDC59_RS13905 3f42313d83861e50d5b59ba77f8f00c6 422 Gene3D G3DSA:3.30.870.10 16 191 3.0E-31 T 29-03-2018 CDC59_RS13905 3f42313d83861e50d5b59ba77f8f00c6 422 SUPERFAMILY SSF56024 229 399 5.38E-35 T 29-03-2018 CDC59_RS13905 3f42313d83861e50d5b59ba77f8f00c6 422 Gene3D G3DSA:3.30.870.10 232 398 6.3E-29 T 29-03-2018 CDC59_RS13905 3f42313d83861e50d5b59ba77f8f00c6 422 Pfam PF13091 PLD-like domain 253 375 4.1E-24 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CDC59_RS13905 3f42313d83861e50d5b59ba77f8f00c6 422 Pfam PF13091 PLD-like domain 38 144 2.4E-12 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CDC59_RS13905 3f42313d83861e50d5b59ba77f8f00c6 422 Hamap MF_01917 Cardiolipin synthase B [clsB]. 16 422 47.089 T 29-03-2018 IPR030872 Cardiolipin synthase B GO:0008808|GO:0032049 CDC59_RS13905 3f42313d83861e50d5b59ba77f8f00c6 422 SUPERFAMILY SSF56024 14 186 3.66E-43 T 29-03-2018 CDC59_RS13905 3f42313d83861e50d5b59ba77f8f00c6 422 SMART SM00155 324 351 0.028 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CDC59_RS13905 3f42313d83861e50d5b59ba77f8f00c6 422 SMART SM00155 121 148 5.8E-5 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CDC59_RS13905 3f42313d83861e50d5b59ba77f8f00c6 422 PIRSF PIRSF000850 297 390 1.9 T 29-03-2018 CDC59_RS13905 3f42313d83861e50d5b59ba77f8f00c6 422 PIRSF PIRSF000850 19 162 1.2E-7 T 29-03-2018 CDC59_RS13905 3f42313d83861e50d5b59ba77f8f00c6 422 PIRSF PIRSF000850 230 308 2.1 T 29-03-2018 CDC59_RS01745 2070c70c739298c738086539ba427ff3 228 Pfam PF11356 Type II secretion system protein C 69 129 3.0E-6 T 29-03-2018 IPR024961 Type II secretion system protein C, N-terminal CDC59_RS18795 6d682d5d8420315cb9a584998f9a7835 589 PRINTS PR00301 70kDa heat shock protein signature 349 369 5.1E-47 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CDC59_RS18795 6d682d5d8420315cb9a584998f9a7835 589 PRINTS PR00301 70kDa heat shock protein signature 374 393 5.1E-47 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CDC59_RS18795 6d682d5d8420315cb9a584998f9a7835 589 PRINTS PR00301 70kDa heat shock protein signature 130 150 5.1E-47 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CDC59_RS18795 6d682d5d8420315cb9a584998f9a7835 589 PRINTS PR00301 70kDa heat shock protein signature 463 479 5.1E-47 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CDC59_RS18795 6d682d5d8420315cb9a584998f9a7835 589 PRINTS PR00301 70kDa heat shock protein signature 47 59 5.1E-47 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CDC59_RS18795 6d682d5d8420315cb9a584998f9a7835 589 PRINTS PR00301 70kDa heat shock protein signature 19 32 5.1E-47 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CDC59_RS18795 6d682d5d8420315cb9a584998f9a7835 589 PRINTS PR00301 70kDa heat shock protein signature 318 334 5.1E-47 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CDC59_RS18795 6d682d5d8420315cb9a584998f9a7835 589 PRINTS PR00301 70kDa heat shock protein signature 189 199 5.1E-47 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CDC59_RS18795 6d682d5d8420315cb9a584998f9a7835 589 Gene3D G3DSA:3.30.420.40 18 187 2.2E-56 T 29-03-2018 CDC59_RS18795 6d682d5d8420315cb9a584998f9a7835 589 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 321 335 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CDC59_RS18795 6d682d5d8420315cb9a584998f9a7835 589 Gene3D G3DSA:3.30.420.40 188 347 1.1E-36 T 29-03-2018 CDC59_RS18795 6d682d5d8420315cb9a584998f9a7835 589 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 23 30 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CDC59_RS18795 6d682d5d8420315cb9a584998f9a7835 589 SUPERFAMILY SSF53067 178 364 4.41E-46 T 29-03-2018 CDC59_RS18795 6d682d5d8420315cb9a584998f9a7835 589 SUPERFAMILY SSF100920 373 534 3.53E-35 T 29-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CDC59_RS18795 6d682d5d8420315cb9a584998f9a7835 589 SUPERFAMILY SSF53067 20 175 1.25E-48 T 29-03-2018 CDC59_RS18795 6d682d5d8420315cb9a584998f9a7835 589 Pfam PF00012 Hsp70 protein 97 552 2.4E-115 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CDC59_RS18795 6d682d5d8420315cb9a584998f9a7835 589 Pfam PF00012 Hsp70 protein 20 92 2.7E-16 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CDC59_RS18795 6d682d5d8420315cb9a584998f9a7835 589 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 183 196 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CDC59_RS18795 6d682d5d8420315cb9a584998f9a7835 589 Gene3D G3DSA:2.60.34.10 355 543 3.8E-40 T 29-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CDC59_RS00795 0efe5e5d8e8a21b692d23b47d837a4b2 647 Pfam PF13932 GidA associated domain 403 626 4.4E-75 T 29-03-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 CDC59_RS00795 0efe5e5d8e8a21b692d23b47d837a4b2 647 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 7 631 1.0E-272 T 29-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 CDC59_RS00795 0efe5e5d8e8a21b692d23b47d837a4b2 647 SUPERFAMILY SSF51905 6 66 6.64E-49 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS00795 0efe5e5d8e8a21b692d23b47d837a4b2 647 SUPERFAMILY SSF51905 97 262 6.64E-49 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS00795 0efe5e5d8e8a21b692d23b47d837a4b2 647 SMART SM01228 556 627 8.4E-44 T 29-03-2018 CDC59_RS00795 0efe5e5d8e8a21b692d23b47d837a4b2 647 Pfam PF01134 Glucose inhibited division protein A 8 400 2.8E-165 T 29-03-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 CDC59_RS00795 0efe5e5d8e8a21b692d23b47d837a4b2 647 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 5 634 42.672 T 29-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 CDC59_RS00795 0efe5e5d8e8a21b692d23b47d837a4b2 647 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 274 288 - T 29-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 CDC59_RS00795 0efe5e5d8e8a21b692d23b47d837a4b2 647 Gene3D G3DSA:3.50.50.60 5 265 3.4E-77 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS00795 0efe5e5d8e8a21b692d23b47d837a4b2 647 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 369 392 - T 29-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 CDC59_RS07635 5481a4b8e4752a8c5d8097cde94d96a9 247 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS07635 5481a4b8e4752a8c5d8097cde94d96a9 247 Gene3D G3DSA:3.40.50.300 19 247 4.0E-62 T 29-03-2018 CDC59_RS07635 5481a4b8e4752a8c5d8097cde94d96a9 247 SMART SM00382 51 246 2.8E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS07635 5481a4b8e4752a8c5d8097cde94d96a9 247 TIGRFAM TIGR02211 LolD_lipo_ex: lipoprotein releasing system, ATP-binding protein 22 241 4.4E-95 T 29-03-2018 IPR011924 Lipoprotein releasing system, ATP-binding protein GO:0005524|GO:0006810|GO:0016020 CDC59_RS07635 5481a4b8e4752a8c5d8097cde94d96a9 247 SUPERFAMILY SSF52540 22 242 1.24E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS07635 5481a4b8e4752a8c5d8097cde94d96a9 247 Pfam PF00005 ABC transporter 42 190 1.0E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS09640 3d53f9992bb6ec49a74e9c9d85352bf9 196 Pfam PF01613 Flavin reductase like domain 20 153 8.7E-17 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CDC59_RS09640 3d53f9992bb6ec49a74e9c9d85352bf9 196 Gene3D G3DSA:2.30.110.10 9 195 5.4E-39 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CDC59_RS09640 3d53f9992bb6ec49a74e9c9d85352bf9 196 SUPERFAMILY SSF50475 4 186 1.62E-37 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CDC59_RS09640 3d53f9992bb6ec49a74e9c9d85352bf9 196 SMART SM00903 15 162 1.1E-17 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CDC59_RS12590 c9d0b93192f7cbd5361451fc59cec89d 382 SUPERFAMILY SSF142754 45 355 1.96E-107 T 29-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CDC59_RS12590 c9d0b93192f7cbd5361451fc59cec89d 382 Hamap MF_00567 Quinolinate synthase A [nadA]. 6 361 66.065 T 29-03-2018 IPR023513 Quinolinate synthase A, type 1 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CDC59_RS12590 c9d0b93192f7cbd5361451fc59cec89d 382 Gene3D G3DSA:3.40.50.10800 225 337 4.3E-33 T 29-03-2018 CDC59_RS12590 c9d0b93192f7cbd5361451fc59cec89d 382 Gene3D G3DSA:3.40.50.10800 134 224 2.1E-17 T 29-03-2018 CDC59_RS12590 c9d0b93192f7cbd5361451fc59cec89d 382 Pfam PF02445 Quinolinate synthetase A protein 48 354 6.6E-104 T 29-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CDC59_RS12590 c9d0b93192f7cbd5361451fc59cec89d 382 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 42 355 4.1E-110 T 29-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CDC59_RS12590 c9d0b93192f7cbd5361451fc59cec89d 382 Gene3D G3DSA:3.40.50.10800 41 126 2.4E-17 T 29-03-2018 CDC59_RS08950 f90df6bf7fa8c872961c0b2039268389 156 Pfam PF08982 Domain of unknown function (DUF1857) 8 152 1.4E-29 T 29-03-2018 IPR015075 Acetylaranotin biosynthesis cluster protein L CDC59_RS08950 f90df6bf7fa8c872961c0b2039268389 156 Gene3D G3DSA:3.30.530.20 2 154 1.1E-36 T 29-03-2018 IPR023393 START-like domain CDC59_RS08950 f90df6bf7fa8c872961c0b2039268389 156 SUPERFAMILY SSF55961 2 150 3.85E-46 T 29-03-2018 CDC59_RS12085 9f087aaea2e003daed279b1dcfd88147 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 1.3E-43 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CDC59_RS12085 9f087aaea2e003daed279b1dcfd88147 112 PIRSF PIRSF039144 1 112 2.3E-55 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CDC59_RS12085 9f087aaea2e003daed279b1dcfd88147 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 29-03-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 CDC59_RS12085 9f087aaea2e003daed279b1dcfd88147 112 PRINTS PR00340 P-II protein signature 83 103 7.1E-45 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CDC59_RS12085 9f087aaea2e003daed279b1dcfd88147 112 PRINTS PR00340 P-II protein signature 2 17 7.1E-45 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CDC59_RS12085 9f087aaea2e003daed279b1dcfd88147 112 PRINTS PR00340 P-II protein signature 23 41 7.1E-45 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CDC59_RS12085 9f087aaea2e003daed279b1dcfd88147 112 PRINTS PR00340 P-II protein signature 52 75 7.1E-45 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CDC59_RS12085 9f087aaea2e003daed279b1dcfd88147 112 SUPERFAMILY SSF54913 1 112 5.4E-46 T 29-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta CDC59_RS12085 9f087aaea2e003daed279b1dcfd88147 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 29-03-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 CDC59_RS12085 9f087aaea2e003daed279b1dcfd88147 112 Gene3D G3DSA:3.30.70.120 1 108 2.7E-49 T 29-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CDC59_RS12085 9f087aaea2e003daed279b1dcfd88147 112 SMART SM00938 4 105 3.6E-66 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CDC59_RS17580 ba274f39650be001a4a9cfbb22c843eb 254 Gene3D G3DSA:3.40.50.1820 2 246 2.7E-30 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS17580 ba274f39650be001a4a9cfbb22c843eb 254 SUPERFAMILY SSF53474 13 242 1.09E-44 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS17580 ba274f39650be001a4a9cfbb22c843eb 254 Pfam PF00975 Thioesterase domain 19 233 6.8E-41 T 29-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CDC59_RS14670 36c28d4caaf6ad7ffbd2e1dfba545de4 333 SUPERFAMILY SSF102114 64 330 3.01E-67 T 29-03-2018 CDC59_RS14670 36c28d4caaf6ad7ffbd2e1dfba545de4 333 Gene3D G3DSA:3.20.20.70 44 331 3.7E-26 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS14670 36c28d4caaf6ad7ffbd2e1dfba545de4 333 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 43 85 7.8E-7 T 29-03-2018 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CDC59_RS14670 36c28d4caaf6ad7ffbd2e1dfba545de4 333 TIGRFAM TIGR00510 lipA: lipoyl synthase 45 326 5.1E-129 T 29-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CDC59_RS14670 36c28d4caaf6ad7ffbd2e1dfba545de4 333 SMART SM00729 96 304 3.7E-19 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CDC59_RS14670 36c28d4caaf6ad7ffbd2e1dfba545de4 333 Hamap MF_00206 Lipoyl synthase [lipA]. 48 333 152.111 T 29-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CDC59_RS14670 36c28d4caaf6ad7ffbd2e1dfba545de4 333 Pfam PF04055 Radical SAM superfamily 103 262 9.9E-14 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CDC59_RS14670 36c28d4caaf6ad7ffbd2e1dfba545de4 333 PIRSF PIRSF005963 3 333 8.9E-129 T 29-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CDC59_RS13755 69427fc7f11a0653bc7c0cdb2f8ed589 211 Gene3D G3DSA:3.90.280.10 1 204 1.9E-48 T 29-03-2018 IPR008914 Phosphatidylethanolamine-binding protein CDC59_RS13755 69427fc7f11a0653bc7c0cdb2f8ed589 211 Pfam PF01161 Phosphatidylethanolamine-binding protein 31 201 5.3E-38 T 29-03-2018 IPR008914 Phosphatidylethanolamine-binding protein CDC59_RS13755 69427fc7f11a0653bc7c0cdb2f8ed589 211 SUPERFAMILY SSF49777 1 203 3.53E-43 T 29-03-2018 IPR008914 Phosphatidylethanolamine-binding protein CDC59_RS13755 69427fc7f11a0653bc7c0cdb2f8ed589 211 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 81 200 3.2E-18 T 29-03-2018 IPR005247 YbhB/YbcL CDC59_RS11420 9838a63455d9b92db1a595fae273dec9 237 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 10 227 39.961 T 29-03-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 CDC59_RS11420 9838a63455d9b92db1a595fae273dec9 237 SUPERFAMILY SSF51366 10 224 3.92E-54 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CDC59_RS11420 9838a63455d9b92db1a595fae273dec9 237 Gene3D G3DSA:3.20.20.70 9 229 9.6E-64 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS11420 9838a63455d9b92db1a595fae273dec9 237 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 13 222 2.8E-43 T 29-03-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 CDC59_RS19095 9914b44931e50ba07a9d35ab38760a56 243 PIRSF PIRSF036427 3 242 6.3E-63 T 29-03-2018 IPR012382 Precorrin-2 C(20)-methyltransferase GO:0008757|GO:0009236|GO:0030788 CDC59_RS19095 9914b44931e50ba07a9d35ab38760a56 243 TIGRFAM TIGR01467 cobI_cbiL: precorrin-2 C(20)-methyltransferase 5 235 2.2E-73 T 29-03-2018 IPR006364 Precorrin-2 C(20)-methyltransferase domain GO:0008757|GO:0009236 CDC59_RS19095 9914b44931e50ba07a9d35ab38760a56 243 SUPERFAMILY SSF53790 4 238 3.27E-35 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CDC59_RS19095 9914b44931e50ba07a9d35ab38760a56 243 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 6 212 3.2E-41 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CDC59_RS19095 9914b44931e50ba07a9d35ab38760a56 243 Gene3D G3DSA:3.40.1010.10 4 151 2.5E-24 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CDC59_RS21925 d9305ded114c3f34512fc9779edf62d1 301 Pfam PF12945 Flagellar protein YcgR 94 177 4.5E-13 T 29-03-2018 IPR009926 Type III secretion system flagellar brake protein YcgR, N-terminal CDC59_RS21925 d9305ded114c3f34512fc9779edf62d1 301 Gene3D G3DSA:2.30.110.10 91 182 2.0E-16 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CDC59_RS21925 d9305ded114c3f34512fc9779edf62d1 301 Pfam PF07238 PilZ domain 186 291 3.3E-7 T 29-03-2018 IPR009875 PilZ domain GO:0035438 CDC59_RS21925 d9305ded114c3f34512fc9779edf62d1 301 SUPERFAMILY SSF141371 90 187 8.63E-16 T 29-03-2018 CDC59_RS21925 d9305ded114c3f34512fc9779edf62d1 301 Gene3D G3DSA:2.40.10.220 183 296 1.5E-11 T 29-03-2018 CDC59_RS02400 48e95dddf1b5e4e20ef5bffbf06100b1 727 Pfam PF05140 ResB-like family 28 700 1.6E-159 T 29-03-2018 IPR007816 ResB-like domain CDC59_RS21555 07bdcc9812f15cfdfe6a8333ec379a97 323 SUPERFAMILY SSF56349 159 305 1.06E-15 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CDC59_RS21555 07bdcc9812f15cfdfe6a8333ec379a97 323 Gene3D G3DSA:1.10.150.130 20 114 4.7E-9 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal CDC59_RS21555 07bdcc9812f15cfdfe6a8333ec379a97 323 Gene3D G3DSA:1.10.443.10 126 312 1.5E-13 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CDC59_RS21555 07bdcc9812f15cfdfe6a8333ec379a97 323 Pfam PF00589 Phage integrase family 159 300 3.8E-8 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CDC59_RS10460 4bbcfd015b852991cb9f453722aefad6 305 SUPERFAMILY SSF103481 51 159 5.17E-10 T 29-03-2018 CDC59_RS10460 4bbcfd015b852991cb9f453722aefad6 305 Pfam PF00892 EamA-like transporter family 24 157 1.9E-11 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CDC59_RS10460 4bbcfd015b852991cb9f453722aefad6 305 Pfam PF00892 EamA-like transporter family 173 303 7.9E-12 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CDC59_RS10460 4bbcfd015b852991cb9f453722aefad6 305 SUPERFAMILY SSF103481 210 304 5.23E-14 T 29-03-2018 CDC59_RS14175 71423cc0938b59fd79555c2340416b87 554 Gene3D G3DSA:1.20.58.220 435 534 3.2E-9 T 29-03-2018 CDC59_RS14175 71423cc0938b59fd79555c2340416b87 554 SUPERFAMILY SSF109755 320 532 2.51E-33 T 29-03-2018 CDC59_RS14175 71423cc0938b59fd79555c2340416b87 554 TIGRFAM TIGR00704 NaPi_cotrn_rel: Na/Pi-cotransporter II-related protein 1 306 6.4E-77 T 29-03-2018 IPR004633 Na/Pi-cotransporter II-related/YqeW-like protein GO:0016020 CDC59_RS14175 71423cc0938b59fd79555c2340416b87 554 Pfam PF01895 PhoU domain 340 424 8.1E-10 T 29-03-2018 IPR026022 PhoU domain CDC59_RS14175 71423cc0938b59fd79555c2340416b87 554 Pfam PF02690 Na+/Pi-cotransporter 13 147 1.0E-34 T 29-03-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 CDC59_RS14175 71423cc0938b59fd79555c2340416b87 554 Pfam PF02690 Na+/Pi-cotransporter 157 237 2.2E-8 T 29-03-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 CDC59_RS14175 71423cc0938b59fd79555c2340416b87 554 Gene3D G3DSA:1.20.58.220 323 434 1.5E-17 T 29-03-2018 CDC59_RS17205 e2f97a740b6788396481bb4f1e6d7713 326 SMART SM00450 207 306 1.2E-4 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS17205 e2f97a740b6788396481bb4f1e6d7713 326 SUPERFAMILY SSF52821 182 312 2.88E-22 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS17205 e2f97a740b6788396481bb4f1e6d7713 326 Gene3D G3DSA:3.40.250.10 189 324 1.7E-17 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS17205 e2f97a740b6788396481bb4f1e6d7713 326 Pfam PF09335 SNARE associated Golgi protein 30 154 1.1E-15 T 29-03-2018 IPR032816 SNARE associated Golgi protein CDC59_RS17205 e2f97a740b6788396481bb4f1e6d7713 326 Pfam PF00581 Rhodanese-like domain 207 302 1.4E-7 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS09555 c1f5d2d692b80e91c0c7010e7bb1d876 369 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 100 125 - T 29-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 CDC59_RS09555 c1f5d2d692b80e91c0c7010e7bb1d876 369 Gene3D G3DSA:3.30.390.10 1 129 1.8E-35 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CDC59_RS09555 c1f5d2d692b80e91c0c7010e7bb1d876 369 SUPERFAMILY SSF51604 113 367 2.1E-64 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CDC59_RS09555 c1f5d2d692b80e91c0c7010e7bb1d876 369 Gene3D G3DSA:3.20.20.120 130 369 4.5E-56 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CDC59_RS09555 c1f5d2d692b80e91c0c7010e7bb1d876 369 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 191 222 - T 29-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 CDC59_RS09555 c1f5d2d692b80e91c0c7010e7bb1d876 369 SUPERFAMILY SSF54826 2 126 2.55E-35 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CDC59_RS09555 c1f5d2d692b80e91c0c7010e7bb1d876 369 TIGRFAM TIGR02534 mucon_cyclo: muconate and chloromuconate cycloisomerases 2 369 6.6E-177 T 29-03-2018 IPR013370 Muconate/chloromuconate cycloisomerase GO:0018849|GO:0018850|GO:0030145 CDC59_RS09555 c1f5d2d692b80e91c0c7010e7bb1d876 369 SMART SM00922 144 241 2.1E-19 T 29-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CDC59_RS09555 c1f5d2d692b80e91c0c7010e7bb1d876 369 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 5 125 4.4E-35 T 29-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CDC59_RS09555 c1f5d2d692b80e91c0c7010e7bb1d876 369 Pfam PF13378 Enolase C-terminal domain-like 148 361 1.5E-45 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CDC59_RS21935 07aa32ccd8175d499d11eee9e9f1df2e 484 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 15 442 2.2E-152 T 29-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 CDC59_RS21935 07aa32ccd8175d499d11eee9e9f1df2e 484 PIRSF PIRSF006446 8 464 7.3E-174 T 29-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 CDC59_RS12775 6ee11c97ee4282c2890c1b2b8a15b672 542 SUPERFAMILY SSF56235 7 542 2.06E-167 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CDC59_RS12775 6ee11c97ee4282c2890c1b2b8a15b672 542 Pfam PF01019 Gamma-glutamyltranspeptidase 37 537 4.1E-147 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CDC59_RS12775 6ee11c97ee4282c2890c1b2b8a15b672 542 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 119 137 1.2E-36 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CDC59_RS12775 6ee11c97ee4282c2890c1b2b8a15b672 542 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 437 454 1.2E-36 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CDC59_RS12775 6ee11c97ee4282c2890c1b2b8a15b672 542 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 235 251 1.2E-36 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CDC59_RS12775 6ee11c97ee4282c2890c1b2b8a15b672 542 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 137 156 1.2E-36 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CDC59_RS12775 6ee11c97ee4282c2890c1b2b8a15b672 542 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 44 69 1.2E-36 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CDC59_RS12775 6ee11c97ee4282c2890c1b2b8a15b672 542 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 382 400 1.2E-36 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CDC59_RS12775 6ee11c97ee4282c2890c1b2b8a15b672 542 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 264 283 1.2E-36 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CDC59_RS12775 6ee11c97ee4282c2890c1b2b8a15b672 542 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 413 428 1.2E-36 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CDC59_RS12775 6ee11c97ee4282c2890c1b2b8a15b672 542 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 358 376 1.2E-36 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CDC59_RS09370 4ba7aef7f69dc5dd94d3a2d153d24088 304 Pfam PF00753 Metallo-beta-lactamase superfamily 41 229 1.1E-10 T 29-03-2018 IPR001279 Metallo-beta-lactamase CDC59_RS09370 4ba7aef7f69dc5dd94d3a2d153d24088 304 SUPERFAMILY SSF56281 27 252 1.89E-41 T 29-03-2018 IPR001279 Metallo-beta-lactamase CDC59_RS09370 4ba7aef7f69dc5dd94d3a2d153d24088 304 Gene3D G3DSA:3.60.15.10 17 258 1.8E-22 T 29-03-2018 IPR001279 Metallo-beta-lactamase CDC59_RS09370 4ba7aef7f69dc5dd94d3a2d153d24088 304 SMART SM00849 44 229 8.8E-15 T 29-03-2018 IPR001279 Metallo-beta-lactamase CDC59_RS10515 f1f7547e1f9b52fcf7c0fa431bae9d49 289 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 120 1.1E-41 T 29-03-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CDC59_RS10515 f1f7547e1f9b52fcf7c0fa431bae9d49 289 SUPERFAMILY SSF53223 1 121 2.97E-41 T 29-03-2018 CDC59_RS10515 f1f7547e1f9b52fcf7c0fa431bae9d49 289 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 282 38.667 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CDC59_RS10515 f1f7547e1f9b52fcf7c0fa431bae9d49 289 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 124 281 7.4E-69 T 29-03-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CDC59_RS10515 f1f7547e1f9b52fcf7c0fa431bae9d49 289 Gene3D G3DSA:3.40.50.10860 11 139 1.8E-47 T 29-03-2018 CDC59_RS10515 f1f7547e1f9b52fcf7c0fa431bae9d49 289 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 259 267 - T 29-03-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CDC59_RS10515 f1f7547e1f9b52fcf7c0fa431bae9d49 289 ProSitePatterns PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1. 75 100 - T 29-03-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CDC59_RS10515 f1f7547e1f9b52fcf7c0fa431bae9d49 289 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 6.0E-84 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CDC59_RS10515 f1f7547e1f9b52fcf7c0fa431bae9d49 289 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 6.0E-84 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CDC59_RS10515 f1f7547e1f9b52fcf7c0fa431bae9d49 289 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 255 273 6.0E-84 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CDC59_RS10515 f1f7547e1f9b52fcf7c0fa431bae9d49 289 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 6.0E-84 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CDC59_RS10515 f1f7547e1f9b52fcf7c0fa431bae9d49 289 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 238 254 6.0E-84 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CDC59_RS10515 f1f7547e1f9b52fcf7c0fa431bae9d49 289 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 6.0E-84 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CDC59_RS10515 f1f7547e1f9b52fcf7c0fa431bae9d49 289 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 203 232 6.0E-84 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CDC59_RS10515 f1f7547e1f9b52fcf7c0fa431bae9d49 289 Gene3D G3DSA:3.40.50.720 140 263 4.2E-42 T 29-03-2018 CDC59_RS10515 f1f7547e1f9b52fcf7c0fa431bae9d49 289 SUPERFAMILY SSF51735 122 280 1.8E-53 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS01015 174b4bbd0f3d6df0167fe55ca8ec3526 114 Pfam PF07472 Fucose-binding lectin II (PA-IIL) 7 113 2.0E-48 T 29-03-2018 IPR010907 Calcium-mediated lectin CDC59_RS01015 174b4bbd0f3d6df0167fe55ca8ec3526 114 Gene3D G3DSA:2.60.120.400 5 111 2.9E-34 T 29-03-2018 CDC59_RS01015 174b4bbd0f3d6df0167fe55ca8ec3526 114 PIRSF PIRSF029595 1 114 3.3E-66 T 29-03-2018 IPR016927 Lectin, sugar-binding CDC59_RS01015 174b4bbd0f3d6df0167fe55ca8ec3526 114 SUPERFAMILY SSF82026 3 114 1.96E-47 T 29-03-2018 IPR010907 Calcium-mediated lectin CDC59_RS14080 002476a8655541358198a56dfba82911 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 201 221 2.0E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS14080 002476a8655541358198a56dfba82911 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 2.0E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS14080 002476a8655541358198a56dfba82911 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 2.0E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS14080 002476a8655541358198a56dfba82911 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 2.0E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS14080 002476a8655541358198a56dfba82911 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 2.0E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS14080 002476a8655541358198a56dfba82911 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 2.0E-42 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS14080 002476a8655541358198a56dfba82911 238 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 185 4.6E-5 T 29-03-2018 CDC59_RS14080 002476a8655541358198a56dfba82911 238 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 237 3.0E-53 T 29-03-2018 CDC59_RS14080 002476a8655541358198a56dfba82911 238 Gene3D G3DSA:3.40.50.720 1 155 3.6E-44 T 29-03-2018 CDC59_RS14080 002476a8655541358198a56dfba82911 238 SUPERFAMILY SSF51735 2 237 1.31E-71 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS14080 002476a8655541358198a56dfba82911 238 Gene3D G3DSA:3.40.50.720 156 236 2.6E-24 T 29-03-2018 CDC59_RS14080 002476a8655541358198a56dfba82911 238 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 1.3E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS14080 002476a8655541358198a56dfba82911 238 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 1.3E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS14080 002476a8655541358198a56dfba82911 238 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 1.3E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS11810 d5dbd6cad69c5dbea34a523e29a3a422 119 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 22 118 6.0E-38 T 29-03-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS11810 d5dbd6cad69c5dbea34a523e29a3a422 119 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 2 119 20.492 T 29-03-2018 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 CDC59_RS00075 7f122269ee9a818c402c493b47f86826 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 4.3E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDC59_RS00075 7f122269ee9a818c402c493b47f86826 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 4.3E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDC59_RS00075 7f122269ee9a818c402c493b47f86826 219 Pfam PF08361 MAATS-type transcriptional repressor, C-terminal region 83 203 1.3E-43 T 29-03-2018 IPR013572 Transcription regulator MAATS, C-terminal GO:0003677 CDC59_RS00075 7f122269ee9a818c402c493b47f86826 219 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 2.0E-19 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDC59_RS00075 7f122269ee9a818c402c493b47f86826 219 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 58 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CDC59_RS00075 7f122269ee9a818c402c493b47f86826 219 SUPERFAMILY SSF46689 2 75 4.36E-20 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS00075 7f122269ee9a818c402c493b47f86826 219 Gene3D G3DSA:1.10.10.60 2 37 4.2E-18 T 29-03-2018 CDC59_RS00075 7f122269ee9a818c402c493b47f86826 219 SUPERFAMILY SSF48498 82 188 2.27E-12 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CDC59_RS00075 7f122269ee9a818c402c493b47f86826 219 Gene3D G3DSA:1.10.357.10 65 205 1.5E-14 T 29-03-2018 CDC59_RS00075 7f122269ee9a818c402c493b47f86826 219 Gene3D G3DSA:1.10.260.40 38 64 3.9E-14 T 29-03-2018 CDC59_RS05395 f5f0130a6ff8113502dc0a5c70c461cd 308 Pfam PF00106 short chain dehydrogenase 32 142 1.5E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS05395 f5f0130a6ff8113502dc0a5c70c461cd 308 SUPERFAMILY SSF51735 30 276 1.89E-24 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS05395 f5f0130a6ff8113502dc0a5c70c461cd 308 Gene3D G3DSA:3.40.50.720 16 302 5.1E-27 T 29-03-2018 CDC59_RS00835 b6f92ea25001a0f3ac6f20124362e9d2 178 Hamap MF_01416 ATP synthase subunit delta [atpD]. 3 177 18.493 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS00835 b6f92ea25001a0f3ac6f20124362e9d2 178 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 7 175 4.0E-35 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS00835 b6f92ea25001a0f3ac6f20124362e9d2 178 Pfam PF00213 ATP synthase delta (OSCP) subunit 7 175 1.0E-47 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS00835 b6f92ea25001a0f3ac6f20124362e9d2 178 SUPERFAMILY SSF47928 3 105 4.18E-19 T 29-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS00835 b6f92ea25001a0f3ac6f20124362e9d2 178 PRINTS PR00125 ATP synthase delta subunit signature 7 26 1.4E-22 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS00835 b6f92ea25001a0f3ac6f20124362e9d2 178 PRINTS PR00125 ATP synthase delta subunit signature 74 85 1.4E-22 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS00835 b6f92ea25001a0f3ac6f20124362e9d2 178 PRINTS PR00125 ATP synthase delta subunit signature 135 150 1.4E-22 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS00835 b6f92ea25001a0f3ac6f20124362e9d2 178 PRINTS PR00125 ATP synthase delta subunit signature 150 168 1.4E-22 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS00835 b6f92ea25001a0f3ac6f20124362e9d2 178 PRINTS PR00125 ATP synthase delta subunit signature 85 99 1.4E-22 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS00835 b6f92ea25001a0f3ac6f20124362e9d2 178 Gene3D G3DSA:1.10.520.20 2 106 3.5E-24 T 29-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS09540 dacd261b61fee9a36c17f077fa98eff7 166 SUPERFAMILY SSF46785 40 155 1.17E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS09540 dacd261b61fee9a36c17f077fa98eff7 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 100 116 2.3E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS09540 dacd261b61fee9a36c17f077fa98eff7 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 64 80 2.3E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS09540 dacd261b61fee9a36c17f077fa98eff7 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 81 96 2.3E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS09540 dacd261b61fee9a36c17f077fa98eff7 166 Pfam PF01047 MarR family 52 104 4.5E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS09540 dacd261b61fee9a36c17f077fa98eff7 166 Gene3D G3DSA:1.10.10.10 2 159 7.4E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS09540 dacd261b61fee9a36c17f077fa98eff7 166 SMART SM00347 40 140 8.0E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS09540 dacd261b61fee9a36c17f077fa98eff7 166 ProSitePatterns PS01117 MarR-type HTH domain signature. 79 113 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CDC59_RS20630 a5e1d7b4d6e0c76b3f1127d3dff3e0f3 396 Pfam PF05144 Phage replication protein CRI 78 248 9.7E-12 T 29-03-2018 IPR022686 Replication-associated protein G2P, N-terminal GO:0006260 CDC59_RS20630 a5e1d7b4d6e0c76b3f1127d3dff3e0f3 396 TIGRFAM TIGR01629 rep_II_X: phage/plasmid replication protein, gene II/X family 78 347 8.2E-17 T 29-03-2018 IPR006516 Replication-associated protein G2P GO:0006260 CDC59_RS00770 86939916b22066db630b9366d628a5ff 298 Gene3D G3DSA:3.40.190.10 96 181 2.0E-17 T 29-03-2018 CDC59_RS00770 86939916b22066db630b9366d628a5ff 298 Gene3D G3DSA:3.40.190.10 182 269 1.2E-9 T 29-03-2018 CDC59_RS00770 86939916b22066db630b9366d628a5ff 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 66 2.1E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS00770 86939916b22066db630b9366d628a5ff 298 SUPERFAMILY SSF46785 6 116 2.31E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS00770 86939916b22066db630b9366d628a5ff 298 Pfam PF03466 LysR substrate binding domain 92 289 2.4E-30 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS00770 86939916b22066db630b9366d628a5ff 298 Gene3D G3DSA:1.10.10.10 4 91 2.1E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS00770 86939916b22066db630b9366d628a5ff 298 SUPERFAMILY SSF53850 92 291 5.61E-34 T 29-03-2018 CDC59_RS00770 86939916b22066db630b9366d628a5ff 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 1.3E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS00770 86939916b22066db630b9366d628a5ff 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 1.3E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS00770 86939916b22066db630b9366d628a5ff 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 1.3E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS07315 d1c692335e1e174016d5f886b5c9035b 79 Gene3D G3DSA:1.10.1200.10 1 79 3.9E-28 T 29-03-2018 CDC59_RS07315 d1c692335e1e174016d5f886b5c9035b 79 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 41 76 9.0E-14 T 29-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CDC59_RS07315 d1c692335e1e174016d5f886b5c9035b 79 SUPERFAMILY SSF47336 2 76 2.09E-23 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS07315 d1c692335e1e174016d5f886b5c9035b 79 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 1 74 1.0E-35 T 29-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CDC59_RS07315 d1c692335e1e174016d5f886b5c9035b 79 ProSitePatterns PS00012 Phosphopantetheine attachment site. 32 47 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CDC59_RS07315 d1c692335e1e174016d5f886b5c9035b 79 Pfam PF00550 Phosphopantetheine attachment site 6 72 5.8E-17 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS07315 d1c692335e1e174016d5f886b5c9035b 79 Hamap MF_01217 Acyl carrier protein [acpP]. 3 77 22.375 T 29-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CDC59_RS17815 f753ed339dd84d2ebcafd1a1484cc2a8 300 SUPERFAMILY SSF53807 35 295 4.71E-48 T 29-03-2018 CDC59_RS17815 f753ed339dd84d2ebcafd1a1484cc2a8 300 Gene3D G3DSA:3.40.50.1980 34 141 1.6E-22 T 29-03-2018 CDC59_RS17815 f753ed339dd84d2ebcafd1a1484cc2a8 300 Pfam PF01497 Periplasmic binding protein 38 273 2.4E-25 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CDC59_RS17815 f753ed339dd84d2ebcafd1a1484cc2a8 300 Gene3D G3DSA:3.40.50.1980 142 299 7.6E-23 T 29-03-2018 CDC59_RS02590 8199ec9880587f4b959c435736cc8cef 207 Gene3D G3DSA:1.20.1250.20 1 168 5.9E-4 T 29-03-2018 CDC59_RS02590 8199ec9880587f4b959c435736cc8cef 207 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 5 198 4.1E-60 T 29-03-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 CDC59_RS02590 8199ec9880587f4b959c435736cc8cef 207 Pfam PF01914 MarC family integral membrane protein 4 201 1.1E-61 T 29-03-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 CDC59_RS21035 566e0757b5f2ac5d385f8b3d15b03829 310 Gene3D G3DSA:3.40.50.720 5 107 9.4E-8 T 29-03-2018 CDC59_RS21035 566e0757b5f2ac5d385f8b3d15b03829 310 Gene3D G3DSA:3.40.50.720 108 276 1.9E-40 T 29-03-2018 CDC59_RS21035 566e0757b5f2ac5d385f8b3d15b03829 310 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 104 275 9.2E-42 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CDC59_RS21035 566e0757b5f2ac5d385f8b3d15b03829 310 SUPERFAMILY SSF51735 96 276 1.97E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS23055 1cd21c627828848e20fa97b577f5da8c 1143 SUPERFAMILY SSF54523 1024 1143 7.69E-20 T 29-03-2018 CDC59_RS23055 1cd21c627828848e20fa97b577f5da8c 1143 Gene3D G3DSA:2.150.10.10 452 531 7.2E-5 T 29-03-2018 CDC59_RS23055 1cd21c627828848e20fa97b577f5da8c 1143 Gene3D G3DSA:2.150.10.10 554 628 3.5E-5 T 29-03-2018 CDC59_RS23055 1cd21c627828848e20fa97b577f5da8c 1143 Gene3D G3DSA:2.150.10.10 749 851 7.6E-24 T 29-03-2018 CDC59_RS23055 1cd21c627828848e20fa97b577f5da8c 1143 Gene3D G3DSA:2.150.10.10 257 330 1.6E-5 T 29-03-2018 CDC59_RS23055 1cd21c627828848e20fa97b577f5da8c 1143 Gene3D G3DSA:2.150.10.10 160 233 1.1E-5 T 29-03-2018 CDC59_RS23055 1cd21c627828848e20fa97b577f5da8c 1143 Gene3D G3DSA:2.150.10.10 852 921 6.1E-9 T 29-03-2018 CDC59_RS23055 1cd21c627828848e20fa97b577f5da8c 1143 Gene3D G3DSA:2.150.10.10 651 725 1.6E-4 T 29-03-2018 CDC59_RS23055 1cd21c627828848e20fa97b577f5da8c 1143 Gene3D G3DSA:2.150.10.10 930 1041 3.5E-26 T 29-03-2018 CDC59_RS23055 1cd21c627828848e20fa97b577f5da8c 1143 Gene3D G3DSA:2.150.10.10 69 136 3.9E-6 T 29-03-2018 CDC59_RS23055 1cd21c627828848e20fa97b577f5da8c 1143 Gene3D G3DSA:2.150.10.10 1 46 8.2E-6 T 29-03-2018 CDC59_RS23055 1cd21c627828848e20fa97b577f5da8c 1143 SUPERFAMILY SSF101967 863 912 1.18E-5 T 29-03-2018 CDC59_RS23055 1cd21c627828848e20fa97b577f5da8c 1143 Pfam PF05658 Head domain of trimeric autotransporter adhesin 971 995 3.5E-6 T 29-03-2018 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 CDC59_RS23055 1cd21c627828848e20fa97b577f5da8c 1143 Gene3D G3DSA:3.30.1300.30 1042 1143 4.1E-19 T 29-03-2018 CDC59_RS23055 1cd21c627828848e20fa97b577f5da8c 1143 Gene3D G3DSA:2.150.10.10 352 423 8.8E-6 T 29-03-2018 CDC59_RS23055 1cd21c627828848e20fa97b577f5da8c 1143 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1013 1036 1.6E-6 T 29-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 CDC59_RS23055 1cd21c627828848e20fa97b577f5da8c 1143 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 212 256 4.2E-6 T 29-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 CDC59_RS23055 1cd21c627828848e20fa97b577f5da8c 1143 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 704 748 1.1E-7 T 29-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 CDC59_RS23055 1cd21c627828848e20fa97b577f5da8c 1143 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 115 159 1.7E-6 T 29-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 CDC59_RS23055 1cd21c627828848e20fa97b577f5da8c 1143 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 26 69 3.2E-7 T 29-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 CDC59_RS23055 1cd21c627828848e20fa97b577f5da8c 1143 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 891 922 5.2E-10 T 29-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 CDC59_RS23055 1cd21c627828848e20fa97b577f5da8c 1143 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 828 862 2.7E-8 T 29-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 CDC59_RS23055 1cd21c627828848e20fa97b577f5da8c 1143 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 406 450 5.9E-8 T 29-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 CDC59_RS23055 1cd21c627828848e20fa97b577f5da8c 1143 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 607 651 1.8E-8 T 29-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 CDC59_RS23055 1cd21c627828848e20fa97b577f5da8c 1143 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 510 554 2.0E-8 T 29-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 CDC59_RS23055 1cd21c627828848e20fa97b577f5da8c 1143 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 309 353 2.0E-8 T 29-03-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 CDC59_RS23055 1cd21c627828848e20fa97b577f5da8c 1143 Gene3D G3DSA:1.20.5.170 629 650 8.4E-12 T 29-03-2018 CDC59_RS23055 1cd21c627828848e20fa97b577f5da8c 1143 Gene3D G3DSA:1.20.5.170 137 159 5.1E-11 T 29-03-2018 CDC59_RS23055 1cd21c627828848e20fa97b577f5da8c 1143 Gene3D G3DSA:1.20.5.170 331 351 3.2E-12 T 29-03-2018 CDC59_RS23055 1cd21c627828848e20fa97b577f5da8c 1143 Gene3D G3DSA:1.20.5.170 726 748 5.3E-9 T 29-03-2018 CDC59_RS23055 1cd21c627828848e20fa97b577f5da8c 1143 Gene3D G3DSA:1.20.5.170 424 451 3.3E-10 T 29-03-2018 CDC59_RS23055 1cd21c627828848e20fa97b577f5da8c 1143 Gene3D G3DSA:1.20.5.170 234 256 3.1E-11 T 29-03-2018 CDC59_RS23055 1cd21c627828848e20fa97b577f5da8c 1143 Gene3D G3DSA:1.20.5.170 47 68 7.8E-11 T 29-03-2018 CDC59_RS23055 1cd21c627828848e20fa97b577f5da8c 1143 Gene3D G3DSA:1.20.5.170 532 553 3.2E-12 T 29-03-2018 CDC59_RS23055 1cd21c627828848e20fa97b577f5da8c 1143 SUPERFAMILY SSF101967 939 1035 5.62E-23 T 29-03-2018 CDC59_RS23055 1cd21c627828848e20fa97b577f5da8c 1143 Pfam PF03895 YadA-like membrane anchor domain 1085 1143 5.9E-14 T 29-03-2018 IPR005594 YadA-like, C-terminal CDC59_RS23055 1cd21c627828848e20fa97b577f5da8c 1143 SUPERFAMILY SSF101967 738 849 1.09E-22 T 29-03-2018 CDC59_RS16860 35958ca7eed371e892cbd79eb369071f 256 Pfam PF00486 Transcriptional regulatory protein, C terminal 181 252 2.3E-17 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDC59_RS16860 35958ca7eed371e892cbd79eb369071f 256 SMART SM00448 27 137 2.2E-37 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS16860 35958ca7eed371e892cbd79eb369071f 256 Gene3D G3DSA:3.40.50.2300 16 147 4.4E-36 T 29-03-2018 CDC59_RS16860 35958ca7eed371e892cbd79eb369071f 256 Pfam PF00072 Response regulator receiver domain 29 136 3.0E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS16860 35958ca7eed371e892cbd79eb369071f 256 SMART SM00862 178 252 6.9E-20 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDC59_RS16860 35958ca7eed371e892cbd79eb369071f 256 Gene3D G3DSA:1.10.10.10 148 254 1.1E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS16860 35958ca7eed371e892cbd79eb369071f 256 SUPERFAMILY SSF46894 151 253 6.24E-20 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CDC59_RS16860 35958ca7eed371e892cbd79eb369071f 256 SUPERFAMILY SSF52172 22 150 2.99E-39 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS02745 784ef053ee6e9a212ec73cfbfa416b85 185 Gene3D G3DSA:1.10.10.10 88 182 1.3E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS02745 784ef053ee6e9a212ec73cfbfa416b85 185 SUPERFAMILY SSF88659 107 180 2.62E-14 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS02745 784ef053ee6e9a212ec73cfbfa416b85 185 SUPERFAMILY SSF88946 23 107 4.32E-8 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS02745 784ef053ee6e9a212ec73cfbfa416b85 185 Gene3D G3DSA:1.10.1740.10 21 87 3.3E-10 T 29-03-2018 CDC59_RS02745 784ef053ee6e9a212ec73cfbfa416b85 185 Pfam PF08281 Sigma-70, region 4 123 175 1.6E-16 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS02745 784ef053ee6e9a212ec73cfbfa416b85 185 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 25 179 9.3E-22 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS02745 784ef053ee6e9a212ec73cfbfa416b85 185 Pfam PF04542 Sigma-70 region 2 27 90 4.8E-7 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS09185 e48341f9ac73e08a76fcb04c5133bfb8 462 SMART SM00228 220 287 2.0E-9 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CDC59_RS09185 e48341f9ac73e08a76fcb04c5133bfb8 462 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 2 458 3.1E-93 T 29-03-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 CDC59_RS09185 e48341f9ac73e08a76fcb04c5133bfb8 462 Gene3D G3DSA:2.30.42.10 134 217 4.6E-4 T 29-03-2018 CDC59_RS09185 e48341f9ac73e08a76fcb04c5133bfb8 462 Gene3D G3DSA:2.30.42.10 218 306 6.9E-16 T 29-03-2018 CDC59_RS09185 e48341f9ac73e08a76fcb04c5133bfb8 462 SUPERFAMILY SSF50156 221 306 3.29E-14 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CDC59_RS09185 e48341f9ac73e08a76fcb04c5133bfb8 462 SUPERFAMILY SSF50156 93 193 7.1E-8 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CDC59_RS09185 e48341f9ac73e08a76fcb04c5133bfb8 462 Pfam PF02163 Peptidase family M50 6 445 1.3E-74 T 29-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 CDC59_RS03830 2425ec7aa0f8d1b787b84e33f25ef508 322 SUPERFAMILY SSF63829 5 287 2.16E-13 T 29-03-2018 CDC59_RS03830 2425ec7aa0f8d1b787b84e33f25ef508 322 Gene3D G3DSA:2.120.10.30 1 184 1.8E-5 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CDC59_RS03830 2425ec7aa0f8d1b787b84e33f25ef508 322 Gene3D G3DSA:2.120.10.30 185 322 2.1E-7 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CDC59_RS06915 f27696d4d11cd3673984caa01bb2e401 635 SUPERFAMILY SSF52540 314 512 3.41E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS06915 f27696d4d11cd3673984caa01bb2e401 635 Gene3D G3DSA:3.40.50.300 292 551 7.4E-55 T 29-03-2018 CDC59_RS06915 f27696d4d11cd3673984caa01bb2e401 635 Pfam PF00005 ABC transporter 19 185 2.2E-24 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS06915 f27696d4d11cd3673984caa01bb2e401 635 Pfam PF00005 ABC transporter 336 469 2.8E-23 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS06915 f27696d4d11cd3673984caa01bb2e401 635 Pfam PF12848 ABC transporter 224 298 7.0E-10 T 29-03-2018 IPR032781 ABC-transporter extension domain CDC59_RS06915 f27696d4d11cd3673984caa01bb2e401 635 Pfam PF16326 ABC transporter C-terminal domain 561 629 4.2E-20 T 29-03-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 CDC59_RS06915 f27696d4d11cd3673984caa01bb2e401 635 SUPERFAMILY SSF52540 6 231 5.33E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS06915 f27696d4d11cd3673984caa01bb2e401 635 Gene3D G3DSA:3.40.50.300 74 291 8.9E-42 T 29-03-2018 CDC59_RS06915 f27696d4d11cd3673984caa01bb2e401 635 Gene3D G3DSA:3.40.50.300 9 73 5.3E-7 T 29-03-2018 CDC59_RS06915 f27696d4d11cd3673984caa01bb2e401 635 ProSitePatterns PS00211 ABC transporters family signature. 441 455 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS06915 f27696d4d11cd3673984caa01bb2e401 635 SMART SM00382 344 514 7.7E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS06915 f27696d4d11cd3673984caa01bb2e401 635 SMART SM00382 28 230 2.8E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS03450 daa74a18a5fd3e283fa2460adf7a7992 210 Pfam PF05728 Uncharacterised protein family (UPF0227) 4 192 3.8E-69 T 29-03-2018 IPR008886 Uncharacterised protein family UPF0227/Esterase YqiA CDC59_RS03450 daa74a18a5fd3e283fa2460adf7a7992 210 Gene3D G3DSA:3.40.50.1820 3 192 1.2E-18 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS03450 daa74a18a5fd3e283fa2460adf7a7992 210 SUPERFAMILY SSF53474 5 191 1.43E-16 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS03095 e1fcc6870ff03e7da153ae6fe65fdfc5 108 Pfam PF04999 Cell division protein FtsL 2 78 7.4E-18 T 29-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 CDC59_RS03095 e1fcc6870ff03e7da153ae6fe65fdfc5 108 Hamap MF_00910 Cell division protein FtsL [ftsL]. 1 84 16.199 T 29-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 CDC59_RS03095 e1fcc6870ff03e7da153ae6fe65fdfc5 108 TIGRFAM TIGR02209 ftsL_broad: cell division protein FtsL 1 83 3.2E-28 T 29-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 CDC59_RS15615 2e7345b7eebfc6df3a58746d514e9e77 275 Pfam PF05690 Thiazole biosynthesis protein ThiG 15 261 1.4E-107 T 29-03-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 CDC59_RS15615 2e7345b7eebfc6df3a58746d514e9e77 275 Gene3D G3DSA:3.20.20.70 10 274 9.1E-44 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS15615 2e7345b7eebfc6df3a58746d514e9e77 275 SUPERFAMILY SSF110399 11 253 9.55E-81 T 29-03-2018 CDC59_RS15615 2e7345b7eebfc6df3a58746d514e9e77 275 Hamap MF_00443 Thiazole synthase [thiG]. 12 267 41.579 T 29-03-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 CDC59_RS16100 2668a070919b5e9c85c4f3ff6f46389b 409 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 84 322 2.1E-50 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CDC59_RS16100 2668a070919b5e9c85c4f3ff6f46389b 409 Gene3D G3DSA:1.20.1600.10 144 318 5.9E-23 T 29-03-2018 CDC59_RS16100 2668a070919b5e9c85c4f3ff6f46389b 409 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 73 387 8.8E-42 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 CDC59_RS16100 2668a070919b5e9c85c4f3ff6f46389b 409 Pfam PF00529 HlyD membrane-fusion protein of T1SS 27 312 1.5E-6 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 CDC59_RS16100 2668a070919b5e9c85c4f3ff6f46389b 409 Gene3D G3DSA:3.90.1170.30 8 143 6.3E-4 T 29-03-2018 CDC59_RS16100 2668a070919b5e9c85c4f3ff6f46389b 409 SUPERFAMILY SSF111369 98 328 1.19E-21 T 29-03-2018 CDC59_RS10175 f64045bd7b6716be1bce1e91fb08f88f 424 SMART SM00382 114 266 2.0E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS10175 f64045bd7b6716be1bce1e91fb08f88f 424 Gene3D G3DSA:1.10.8.60 318 409 1.2E-30 T 29-03-2018 CDC59_RS10175 f64045bd7b6716be1bce1e91fb08f88f 424 SMART SM01086 318 412 1.1E-33 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CDC59_RS10175 f64045bd7b6716be1bce1e91fb08f88f 424 SUPERFAMILY SSF52540 64 399 1.45E-76 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS10175 f64045bd7b6716be1bce1e91fb08f88f 424 SUPERFAMILY SSF57716 13 48 1.01E-11 T 29-03-2018 CDC59_RS10175 f64045bd7b6716be1bce1e91fb08f88f 424 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 318 393 5.2E-15 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CDC59_RS10175 f64045bd7b6716be1bce1e91fb08f88f 424 Pfam PF07724 AAA domain (Cdc48 subfamily) 115 311 4.6E-49 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CDC59_RS10175 f64045bd7b6716be1bce1e91fb08f88f 424 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 10 412 1.2E-204 T 29-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 CDC59_RS10175 f64045bd7b6716be1bce1e91fb08f88f 424 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 416 53.597 T 29-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 CDC59_RS10175 f64045bd7b6716be1bce1e91fb08f88f 424 SMART SM00994 12 51 8.7E-24 T 29-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 CDC59_RS10175 f64045bd7b6716be1bce1e91fb08f88f 424 Pfam PF06689 ClpX C4-type zinc finger 13 49 1.2E-19 T 29-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 CDC59_RS10175 f64045bd7b6716be1bce1e91fb08f88f 424 Gene3D G3DSA:3.40.50.300 61 316 1.8E-73 T 29-03-2018 CDC59_RS16935 125feedabd25fa58b0085ed1e98557c9 144 Gene3D G3DSA:3.30.300.20 48 144 1.8E-22 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CDC59_RS16935 125feedabd25fa58b0085ed1e98557c9 144 Gene3D G3DSA:2.20.25.10 4 46 4.1E-18 T 29-03-2018 CDC59_RS16935 125feedabd25fa58b0085ed1e98557c9 144 Pfam PF02566 OsmC-like protein 42 139 1.9E-16 T 29-03-2018 IPR003718 OsmC/Ohr family CDC59_RS16935 125feedabd25fa58b0085ed1e98557c9 144 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 6 140 2.6E-47 T 29-03-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 CDC59_RS16935 125feedabd25fa58b0085ed1e98557c9 144 SUPERFAMILY SSF82784 3 142 3.01E-36 T 29-03-2018 IPR003718 OsmC/Ohr family CDC59_RS19090 290976928b881a907aea55c3b945e954 278 SUPERFAMILY SSF53790 2 233 6.28E-65 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CDC59_RS19090 290976928b881a907aea55c3b945e954 278 TIGRFAM TIGR01465 cobM_cbiF: precorrin-4 C11-methyltransferase 3 249 2.2E-105 T 29-03-2018 IPR006362 Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase GO:0009236|GO:0046026 CDC59_RS19090 290976928b881a907aea55c3b945e954 278 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 6 20 - T 29-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CDC59_RS19090 290976928b881a907aea55c3b945e954 278 Gene3D G3DSA:3.30.950.10 121 233 1.7E-27 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CDC59_RS19090 290976928b881a907aea55c3b945e954 278 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 76 109 - T 29-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CDC59_RS19090 290976928b881a907aea55c3b945e954 278 Gene3D G3DSA:3.40.1010.10 1 120 2.5E-29 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CDC59_RS19090 290976928b881a907aea55c3b945e954 278 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 2 208 1.7E-49 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CDC59_RS01645 2b447b7bf2482a7f8dbf719a256c311b 489 Gene3D G3DSA:3.30.420.10 11 207 1.1E-23 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDC59_RS01645 2b447b7bf2482a7f8dbf719a256c311b 489 PIRSF PIRSF000977 10 489 7.8E-203 T 29-03-2018 IPR023607 Exodeoxyribonuclease I GO:0004529 CDC59_RS01645 2b447b7bf2482a7f8dbf719a256c311b 489 SUPERFAMILY SSF53098 16 486 3.72E-121 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDC59_RS01645 2b447b7bf2482a7f8dbf719a256c311b 489 Pfam PF00929 Exonuclease 18 199 3.4E-20 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CDC59_RS01645 2b447b7bf2482a7f8dbf719a256c311b 489 Pfam PF08411 Exonuclease C-terminal 218 485 1.0E-94 T 29-03-2018 IPR013620 Exodeoxyribonuclease I, C-terminal GO:0006281|GO:0008852 CDC59_RS18170 5d6b55cb63d068aa821ab356231d3a8a 440 Gene3D G3DSA:2.60.40.10 22 121 2.5E-15 T 29-03-2018 IPR013783 Immunoglobulin-like fold CDC59_RS18170 5d6b55cb63d068aa821ab356231d3a8a 440 SUPERFAMILY SSF48726 30 102 4.03E-13 T 29-03-2018 IPR007110 Immunoglobulin-like domain CDC59_RS18170 5d6b55cb63d068aa821ab356231d3a8a 440 Pfam PF12006 Protein of unknown function (DUF3500) 125 436 2.3E-70 T 29-03-2018 IPR021889 Protein of unknown function DUF3500 CDC59_RS18170 5d6b55cb63d068aa821ab356231d3a8a 440 Pfam PF13927 Immunoglobulin domain 30 96 2.8E-8 T 29-03-2018 CDC59_RS18170 5d6b55cb63d068aa821ab356231d3a8a 440 SMART SM00409 36 111 5.4E-6 T 29-03-2018 IPR003599 Immunoglobulin subtype CDC59_RS15675 2aea43c30f0f7072accee481a57aeecb 205 SUPERFAMILY SSF50475 26 176 1.36E-22 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CDC59_RS15675 2aea43c30f0f7072accee481a57aeecb 205 Gene3D G3DSA:2.30.110.10 23 179 1.2E-30 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CDC59_RS15675 2aea43c30f0f7072accee481a57aeecb 205 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 33 123 5.8E-16 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CDC59_RS15675 2aea43c30f0f7072accee481a57aeecb 205 TIGRFAM TIGR04025 PPOX_FMN_DR2398: pyridoxamine 5'-phosphate oxidase, FMN-binding family 11 205 2.8E-82 T 29-03-2018 IPR024029 Pyridoxamine 5-phosphate oxidase, FMN-dependent CDC59_RS20255 68002af77423fe79d43b7255c5fe709f 890 Gene3D G3DSA:3.80.10.10 430 885 3.4E-34 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like CDC59_RS20255 68002af77423fe79d43b7255c5fe709f 890 Gene3D G3DSA:3.80.10.10 149 266 1.1E-14 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like CDC59_RS20255 68002af77423fe79d43b7255c5fe709f 890 Pfam PF13855 Leucine rich repeat 491 550 5.9E-10 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS20255 68002af77423fe79d43b7255c5fe709f 890 Pfam PF13855 Leucine rich repeat 376 434 8.4E-8 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS20255 68002af77423fe79d43b7255c5fe709f 890 Pfam PF13855 Leucine rich repeat 283 342 1.9E-9 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS20255 68002af77423fe79d43b7255c5fe709f 890 SUPERFAMILY SSF52058 175 371 5.78E-32 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like CDC59_RS20255 68002af77423fe79d43b7255c5fe709f 890 SMART SM00364 397 417 76.0 T 29-03-2018 CDC59_RS20255 68002af77423fe79d43b7255c5fe709f 890 SMART SM00364 421 440 1.0 T 29-03-2018 CDC59_RS20255 68002af77423fe79d43b7255c5fe709f 890 SMART SM00364 443 462 590.0 T 29-03-2018 CDC59_RS20255 68002af77423fe79d43b7255c5fe709f 890 SMART SM00364 329 348 180.0 T 29-03-2018 CDC59_RS20255 68002af77423fe79d43b7255c5fe709f 890 SMART SM00364 305 325 98.0 T 29-03-2018 CDC59_RS20255 68002af77423fe79d43b7255c5fe709f 890 SUPERFAMILY SSF52058 329 564 3.91E-41 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like CDC59_RS20255 68002af77423fe79d43b7255c5fe709f 890 SMART SM00369 282 304 12.0 T 29-03-2018 IPR003591 Leucine-rich repeat, typical subtype CDC59_RS20255 68002af77423fe79d43b7255c5fe709f 890 SMART SM00369 237 260 70.0 T 29-03-2018 IPR003591 Leucine-rich repeat, typical subtype CDC59_RS20255 68002af77423fe79d43b7255c5fe709f 890 SMART SM00369 490 514 99.0 T 29-03-2018 IPR003591 Leucine-rich repeat, typical subtype CDC59_RS20255 68002af77423fe79d43b7255c5fe709f 890 SMART SM00369 305 328 58.0 T 29-03-2018 IPR003591 Leucine-rich repeat, typical subtype CDC59_RS20255 68002af77423fe79d43b7255c5fe709f 890 SMART SM00369 374 397 1.5 T 29-03-2018 IPR003591 Leucine-rich repeat, typical subtype CDC59_RS20255 68002af77423fe79d43b7255c5fe709f 890 SMART SM00369 329 352 2.7 T 29-03-2018 IPR003591 Leucine-rich repeat, typical subtype CDC59_RS20255 68002af77423fe79d43b7255c5fe709f 890 SMART SM00369 421 446 0.31 T 29-03-2018 IPR003591 Leucine-rich repeat, typical subtype CDC59_RS20255 68002af77423fe79d43b7255c5fe709f 890 Gene3D G3DSA:3.80.10.10 267 331 1.5E-18 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like CDC59_RS20255 68002af77423fe79d43b7255c5fe709f 890 Gene3D G3DSA:3.80.10.10 332 429 8.2E-25 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like CDC59_RS12265 7d4c5a2f55a35d29493aacddb98efdf1 209 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 149 166 6.1E-8 T 29-03-2018 CDC59_RS12265 7d4c5a2f55a35d29493aacddb98efdf1 209 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 167 186 6.1E-8 T 29-03-2018 CDC59_RS12265 7d4c5a2f55a35d29493aacddb98efdf1 209 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 187 207 6.1E-8 T 29-03-2018 CDC59_RS12265 7d4c5a2f55a35d29493aacddb98efdf1 209 Gene3D G3DSA:3.30.1330.60 70 208 3.1E-43 T 29-03-2018 IPR006665 OmpA-like domain CDC59_RS12265 7d4c5a2f55a35d29493aacddb98efdf1 209 Pfam PF00691 OmpA family 104 198 2.1E-23 T 29-03-2018 IPR006665 OmpA-like domain CDC59_RS12265 7d4c5a2f55a35d29493aacddb98efdf1 209 Pfam PF13441 YMGG-like Gly-zipper 24 66 9.1E-8 T 29-03-2018 IPR027367 YMGG-like Gly-zipper CDC59_RS12265 7d4c5a2f55a35d29493aacddb98efdf1 209 SUPERFAMILY SSF103088 92 206 1.57E-39 T 29-03-2018 IPR006665 OmpA-like domain CDC59_RS12265 7d4c5a2f55a35d29493aacddb98efdf1 209 ProSitePatterns PS01068 OmpA-like domain. 136 180 - T 29-03-2018 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 CDC59_RS12265 7d4c5a2f55a35d29493aacddb98efdf1 209 PRINTS PR01021 OMPA domain signature 134 149 1.6E-15 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CDC59_RS12265 7d4c5a2f55a35d29493aacddb98efdf1 209 PRINTS PR01021 OMPA domain signature 149 165 1.6E-15 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CDC59_RS12265 7d4c5a2f55a35d29493aacddb98efdf1 209 PRINTS PR01021 OMPA domain signature 104 126 1.6E-15 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CDC59_RS06730 1c84360682063e15eb7ea9eef9417d81 262 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 228 1.4E-91 T 29-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CDC59_RS06730 1c84360682063e15eb7ea9eef9417d81 262 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 262 109.125 T 29-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CDC59_RS06730 1c84360682063e15eb7ea9eef9417d81 262 Gene3D G3DSA:3.40.1280.10 1 170 1.5E-69 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CDC59_RS06730 1c84360682063e15eb7ea9eef9417d81 262 Gene3D G3DSA:1.10.1270.20 171 259 3.1E-31 T 29-03-2018 CDC59_RS06730 1c84360682063e15eb7ea9eef9417d81 262 PIRSF PIRSF000386 1 257 2.0E-95 T 29-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CDC59_RS06730 1c84360682063e15eb7ea9eef9417d81 262 SUPERFAMILY SSF75217 1 230 2.35E-96 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases CDC59_RS06730 1c84360682063e15eb7ea9eef9417d81 262 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 23 222 8.1E-61 T 29-03-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CDC59_RS11335 6160f315327d25874b3bf861583d4b2b 93 Gene3D G3DSA:2.10.70.10 57 93 4.3E-17 T 29-03-2018 CDC59_RS11335 6160f315327d25874b3bf861583d4b2b 93 Pfam PF10636 Hemin uptake protein hemP 58 93 3.4E-17 T 29-03-2018 IPR019600 Hemin uptake protein HemP CDC59_RS17425 e753e73d2c38055797ef0a6c8b9a7558 256 SUPERFAMILY SSF56300 12 248 2.31E-47 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CDC59_RS17425 e753e73d2c38055797ef0a6c8b9a7558 256 Gene3D G3DSA:3.60.21.10 2 255 1.5E-34 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CDC59_RS17425 e753e73d2c38055797ef0a6c8b9a7558 256 Pfam PF00149 Calcineurin-like phosphoesterase 12 203 2.6E-17 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CDC59_RS17425 e753e73d2c38055797ef0a6c8b9a7558 256 Hamap MF_00905 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [cpdA]. 10 256 34.279 T 29-03-2018 IPR026575 3,5-cyclic adenosine monophosphate phosphodiesterase CpdA GO:0004115 KEGG: 00230+3.1.4.53 CDC59_RS17480 ddab66c0449c6473353e6c2bf8d2f939 291 Gene3D G3DSA:3.40.190.10 185 262 2.0E-10 T 29-03-2018 CDC59_RS17480 ddab66c0449c6473353e6c2bf8d2f939 291 Gene3D G3DSA:3.40.190.10 89 184 6.2E-15 T 29-03-2018 CDC59_RS17480 ddab66c0449c6473353e6c2bf8d2f939 291 SUPERFAMILY SSF53850 86 289 3.12E-25 T 29-03-2018 CDC59_RS17480 ddab66c0449c6473353e6c2bf8d2f939 291 SUPERFAMILY SSF46785 1 85 1.03E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS17480 ddab66c0449c6473353e6c2bf8d2f939 291 Gene3D G3DSA:1.10.10.10 1 83 9.8E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS17480 ddab66c0449c6473353e6c2bf8d2f939 291 Pfam PF03466 LysR substrate binding domain 85 287 1.3E-29 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS17480 ddab66c0449c6473353e6c2bf8d2f939 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 8.4E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS16825 b1154365ab87432446e719433bf60c51 362 Gene3D G3DSA:3.20.20.70 4 360 1.5E-48 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS16825 b1154365ab87432446e719433bf60c51 362 SUPERFAMILY SSF51412 7 335 4.12E-66 T 29-03-2018 CDC59_RS16825 b1154365ab87432446e719433bf60c51 362 Pfam PF03060 Nitronate monooxygenase 7 334 7.4E-76 T 29-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CDC59_RS12995 619cb3757afc0479b92695c2cc323976 163 Gene3D G3DSA:3.90.960.10 1 162 1.1E-35 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CDC59_RS12995 619cb3757afc0479b92695c2cc323976 163 PIRSF PIRSF006181 5 162 1.4E-44 T 29-03-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC CDC59_RS12995 619cb3757afc0479b92695c2cc323976 163 Pfam PF04073 Aminoacyl-tRNA editing domain 38 148 2.6E-23 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CDC59_RS12995 619cb3757afc0479b92695c2cc323976 163 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 10 155 8.3E-47 T 29-03-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC CDC59_RS12995 619cb3757afc0479b92695c2cc323976 163 SUPERFAMILY SSF55826 7 159 8.11E-41 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CDC59_RS00250 626a4ff4ed4522c06e658f0b8fd1090e 328 Pfam PF05598 Transposase domain (DUF772) 51 126 2.7E-23 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS00250 626a4ff4ed4522c06e658f0b8fd1090e 328 Pfam PF01609 Transposase DDE domain 138 312 2.4E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS19010 626a4ff4ed4522c06e658f0b8fd1090e 328 Pfam PF05598 Transposase domain (DUF772) 51 126 2.7E-23 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS19010 626a4ff4ed4522c06e658f0b8fd1090e 328 Pfam PF01609 Transposase DDE domain 138 312 2.4E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS18005 626a4ff4ed4522c06e658f0b8fd1090e 328 Pfam PF05598 Transposase domain (DUF772) 51 126 2.7E-23 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS18005 626a4ff4ed4522c06e658f0b8fd1090e 328 Pfam PF01609 Transposase DDE domain 138 312 2.4E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS18770 626a4ff4ed4522c06e658f0b8fd1090e 328 Pfam PF05598 Transposase domain (DUF772) 51 126 2.7E-23 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS18770 626a4ff4ed4522c06e658f0b8fd1090e 328 Pfam PF01609 Transposase DDE domain 138 312 2.4E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS22365 626a4ff4ed4522c06e658f0b8fd1090e 328 Pfam PF05598 Transposase domain (DUF772) 51 126 2.7E-23 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS22365 626a4ff4ed4522c06e658f0b8fd1090e 328 Pfam PF01609 Transposase DDE domain 138 312 2.4E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS14520 8379e204c3f98e9baf3941b5deb482bb 249 Pfam PF00899 ThiF family 9 242 5.2E-60 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CDC59_RS14520 8379e204c3f98e9baf3941b5deb482bb 249 SUPERFAMILY SSF69572 2 246 6.54E-84 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CDC59_RS14520 8379e204c3f98e9baf3941b5deb482bb 249 Gene3D G3DSA:3.40.50.720 1 247 3.2E-73 T 29-03-2018 CDC59_RS11535 6f73f9aa026e58099033159e5a71038b 542 Gene3D G3DSA:3.10.105.10 321 515 8.2E-46 T 29-03-2018 CDC59_RS11535 6f73f9aa026e58099033159e5a71038b 542 SUPERFAMILY SSF53850 39 525 9.95E-121 T 29-03-2018 CDC59_RS11535 6f73f9aa026e58099033159e5a71038b 542 Gene3D G3DSA:3.90.76.10 52 190 1.7E-31 T 29-03-2018 CDC59_RS11535 6f73f9aa026e58099033159e5a71038b 542 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 86 445 2.7E-91 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CDC59_RS11535 6f73f9aa026e58099033159e5a71038b 542 Gene3D G3DSA:3.40.190.10 191 320 3.0E-35 T 29-03-2018 CDC59_RS11535 6f73f9aa026e58099033159e5a71038b 542 PIRSF PIRSF002741 8 533 1.3E-97 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CDC59_RS19030 e3b23d7f2aa1e9cd2000a8279e5f80e7 143 Pfam PF01638 HxlR-like helix-turn-helix 28 115 2.5E-27 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type CDC59_RS19030 e3b23d7f2aa1e9cd2000a8279e5f80e7 143 Gene3D G3DSA:1.10.10.10 26 127 2.8E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS19030 e3b23d7f2aa1e9cd2000a8279e5f80e7 143 SUPERFAMILY SSF46785 21 125 1.34E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS23295 6dc5e214eb770ef71c01759fb9fbc72e 83 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 3 54 1.1E-19 T 29-03-2018 CDC59_RS23295 6dc5e214eb770ef71c01759fb9fbc72e 83 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 64 1.6E-15 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CDC59_RS23295 6dc5e214eb770ef71c01759fb9fbc72e 83 SUPERFAMILY SSF143120 1 47 5.49E-11 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CDC59_RS23295 6dc5e214eb770ef71c01759fb9fbc72e 83 Gene3D G3DSA:3.40.1620.10 1 49 2.7E-13 T 29-03-2018 CDC59_RS10970 8c6a8ec57b55ada95e3bff989b95fd37 225 PIRSF PIRSF006324 9 224 2.3E-53 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CDC59_RS10970 8c6a8ec57b55ada95e3bff989b95fd37 225 Pfam PF01810 LysE type translocator 22 221 6.0E-46 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CDC59_RS15465 e89c2e6cf7359a5d670a00fcd4701f5a 275 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 41 259 3.8E-74 T 29-03-2018 IPR022488 Polyphosphate kinase-2-related CDC59_RS15465 e89c2e6cf7359a5d670a00fcd4701f5a 275 SUPERFAMILY SSF52540 67 253 3.8E-18 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS15465 e89c2e6cf7359a5d670a00fcd4701f5a 275 Gene3D G3DSA:3.40.50.300 25 271 2.3E-81 T 29-03-2018 CDC59_RS15465 e89c2e6cf7359a5d670a00fcd4701f5a 275 PIRSF PIRSF028756 10 270 6.4E-78 T 29-03-2018 IPR016898 Polyphosphate kinase 2 CDC59_RS15465 e89c2e6cf7359a5d670a00fcd4701f5a 275 TIGRFAM TIGR03709 PPK2_rel_1: polyphosphate:nucleotide phosphotransferase, PPK2 family 11 269 4.9E-112 T 29-03-2018 IPR022300 Polyphosphate:nucleotide phosphotransferase, PPK2 GO:0006797|GO:0016776 CDC59_RS07245 8babb8e331304b676afdc4d3b22d46b0 373 Gene3D G3DSA:3.20.20.70 31 373 1.6E-84 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS07245 8babb8e331304b676afdc4d3b22d46b0 373 SUPERFAMILY SSF102114 36 346 1.03E-77 T 29-03-2018 CDC59_RS07245 8babb8e331304b676afdc4d3b22d46b0 373 Pfam PF13353 4Fe-4S single cluster domain 51 144 1.9E-9 T 29-03-2018 CDC59_RS07245 8babb8e331304b676afdc4d3b22d46b0 373 Pfam PF04055 Radical SAM superfamily 48 217 5.5E-29 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CDC59_RS07245 8babb8e331304b676afdc4d3b22d46b0 373 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 35 373 41.412 T 29-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 CDC59_RS07245 8babb8e331304b676afdc4d3b22d46b0 373 Pfam PF06463 Molybdenum Cofactor Synthesis C 225 351 3.2E-38 T 29-03-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 Reactome: R-HSA-947581 CDC59_RS07245 8babb8e331304b676afdc4d3b22d46b0 373 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 50 61 - T 29-03-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 Reactome: R-HSA-947581 CDC59_RS07245 8babb8e331304b676afdc4d3b22d46b0 373 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 35 373 3.1E-117 T 29-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 CDC59_RS07245 8babb8e331304b676afdc4d3b22d46b0 373 SMART SM00729 44 257 2.8E-8 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CDC59_RS12075 d59e7b8f295cd09051b5cef3e7919416 221 SUPERFAMILY SSF160443 133 216 3.27E-18 T 29-03-2018 IPR002625 Smr domain CDC59_RS12075 d59e7b8f295cd09051b5cef3e7919416 221 SMART SM00463 132 216 8.9E-12 T 29-03-2018 IPR002625 Smr domain CDC59_RS12075 d59e7b8f295cd09051b5cef3e7919416 221 Pfam PF01713 Smr domain 135 216 6.3E-25 T 29-03-2018 IPR002625 Smr domain CDC59_RS13935 07d146519b3210781e64354b81145e0d 112 SMART SM00834 1 42 5.6E-20 T 29-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CDC59_RS13935 07d146519b3210781e64354b81145e0d 112 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 52 3.3E-23 T 29-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CDC59_RS13935 07d146519b3210781e64354b81145e0d 112 Pfam PF09723 Zinc ribbon domain 1 40 1.1E-16 T 29-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CDC59_RS19985 177c0a031605c28d6edd24868355a84a 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 1.2E-21 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS19985 177c0a031605c28d6edd24868355a84a 298 Gene3D G3DSA:1.10.10.10 1 83 5.3E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS19985 177c0a031605c28d6edd24868355a84a 298 SUPERFAMILY SSF53850 91 295 5.79E-35 T 29-03-2018 CDC59_RS19985 177c0a031605c28d6edd24868355a84a 298 Gene3D G3DSA:3.40.190.10 177 268 1.9E-16 T 29-03-2018 CDC59_RS19985 177c0a031605c28d6edd24868355a84a 298 SUPERFAMILY SSF46785 3 86 3.79E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS19985 177c0a031605c28d6edd24868355a84a 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 3.0E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS19985 177c0a031605c28d6edd24868355a84a 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 3.0E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS19985 177c0a031605c28d6edd24868355a84a 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 3.0E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS19985 177c0a031605c28d6edd24868355a84a 298 Gene3D G3DSA:3.40.190.10 89 176 2.8E-16 T 29-03-2018 CDC59_RS19985 177c0a031605c28d6edd24868355a84a 298 Pfam PF03466 LysR substrate binding domain 89 293 3.1E-37 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS22515 ceb7c010105bd12fdbe3ab86799313bc 213 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 25 196 8.5E-15 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain CDC59_RS22515 ceb7c010105bd12fdbe3ab86799313bc 213 SUPERFAMILY SSF52266 3 210 3.21E-22 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain CDC59_RS22515 ceb7c010105bd12fdbe3ab86799313bc 213 Gene3D G3DSA:3.40.50.1110 1 211 8.3E-20 T 29-03-2018 CDC59_RS08330 c8e1d93c888c889ad22c242e0926e56c 340 Gene3D G3DSA:1.10.3470.10 52 334 2.3E-30 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CDC59_RS08330 c8e1d93c888c889ad22c242e0926e56c 340 Pfam PF02653 Branched-chain amino acid transport system / permease component 59 329 1.3E-46 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CDC59_RS01615 7ee6973652b3d91eeed21ac1d17efcfa 331 Gene3D G3DSA:3.40.50.720 119 302 1.5E-55 T 29-03-2018 CDC59_RS01615 7ee6973652b3d91eeed21ac1d17efcfa 331 Gene3D G3DSA:3.40.50.720 1 118 3.3E-28 T 29-03-2018 CDC59_RS01615 7ee6973652b3d91eeed21ac1d17efcfa 331 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 112 299 5.4E-58 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CDC59_RS01615 7ee6973652b3d91eeed21ac1d17efcfa 331 SUPERFAMILY SSF52283 2 137 4.91E-36 T 29-03-2018 CDC59_RS01615 7ee6973652b3d91eeed21ac1d17efcfa 331 SUPERFAMILY SSF51735 104 300 2.13E-60 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS01615 7ee6973652b3d91eeed21ac1d17efcfa 331 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 225 241 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CDC59_RS01615 7ee6973652b3d91eeed21ac1d17efcfa 331 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 4 329 2.5E-28 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CDC59_RS01615 7ee6973652b3d91eeed21ac1d17efcfa 331 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 149 176 - T 29-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 CDC59_RS01615 7ee6973652b3d91eeed21ac1d17efcfa 331 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 196 218 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CDC59_RS01270 288f49000544f34e95ffc66f120391c5 300 SUPERFAMILY SSF53474 132 274 4.61E-16 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS01270 288f49000544f34e95ffc66f120391c5 300 Gene3D G3DSA:3.40.50.1820 14 281 8.9E-15 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS13810 ec24912c1315fac283910057ed79a2e3 271 Pfam PF11227 Protein of unknown function (DUF3025) 57 261 7.2E-79 T 29-03-2018 IPR021390 Protein of unknown function DUF3025 CDC59_RS00515 8763c883dcbd1e4682c8cae4f8b7585a 937 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 24 232 2.3E-96 T 29-03-2018 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 CDC59_RS00515 8763c883dcbd1e4682c8cae4f8b7585a 937 Pfam PF00512 His Kinase A (phospho-acceptor) domain 704 769 7.9E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS00515 8763c883dcbd1e4682c8cae4f8b7585a 937 SUPERFAMILY SSF52402 253 353 2.18E-5 T 29-03-2018 CDC59_RS00515 8763c883dcbd1e4682c8cae4f8b7585a 937 PRINTS PR00344 Bacterial sensor protein C-terminal signature 911 924 3.5E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS00515 8763c883dcbd1e4682c8cae4f8b7585a 937 PRINTS PR00344 Bacterial sensor protein C-terminal signature 854 868 3.5E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS00515 8763c883dcbd1e4682c8cae4f8b7585a 937 PRINTS PR00344 Bacterial sensor protein C-terminal signature 872 882 3.5E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS00515 8763c883dcbd1e4682c8cae4f8b7585a 937 PRINTS PR00344 Bacterial sensor protein C-terminal signature 887 905 3.5E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS00515 8763c883dcbd1e4682c8cae4f8b7585a 937 SMART SM00387 812 927 2.2E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS00515 8763c883dcbd1e4682c8cae4f8b7585a 937 Gene3D G3DSA:3.40.50.620 248 396 2.8E-9 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDC59_RS00515 8763c883dcbd1e4682c8cae4f8b7585a 937 SUPERFAMILY SSF55781 539 687 2.06E-5 T 29-03-2018 IPR029016 GAF domain-like CDC59_RS00515 8763c883dcbd1e4682c8cae4f8b7585a 937 Gene3D G3DSA:1.20.120.620 432 525 3.1E-29 T 29-03-2018 CDC59_RS00515 8763c883dcbd1e4682c8cae4f8b7585a 937 Gene3D G3DSA:3.30.565.10 756 935 7.9E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS00515 8763c883dcbd1e4682c8cae4f8b7585a 937 Gene3D G3DSA:1.10.287.130 695 755 9.7E-16 T 29-03-2018 CDC59_RS00515 8763c883dcbd1e4682c8cae4f8b7585a 937 SMART SM00388 703 770 1.3E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS00515 8763c883dcbd1e4682c8cae4f8b7585a 937 Gene3D G3DSA:3.30.450.40 526 693 2.4E-8 T 29-03-2018 IPR029016 GAF domain-like CDC59_RS00515 8763c883dcbd1e4682c8cae4f8b7585a 937 Pfam PF13493 Domain of unknown function (DUF4118) 433 538 8.9E-33 T 29-03-2018 IPR025201 Sensor protein KdpD, transmembrane domain CDC59_RS00515 8763c883dcbd1e4682c8cae4f8b7585a 937 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 817 925 1.5E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS00515 8763c883dcbd1e4682c8cae4f8b7585a 937 SUPERFAMILY SSF55874 760 925 1.57E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS00515 8763c883dcbd1e4682c8cae4f8b7585a 937 SUPERFAMILY SSF47384 695 770 1.69E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS00515 8763c883dcbd1e4682c8cae4f8b7585a 937 Pfam PF13492 GAF domain 560 684 3.5E-10 T 29-03-2018 IPR003018 GAF domain GO:0005515 CDC59_RS00515 8763c883dcbd1e4682c8cae4f8b7585a 937 Gene3D G3DSA:3.40.50.300 23 150 9.5E-22 T 29-03-2018 CDC59_RS12800 0d3188eae05ea30b3f62f6ef0a1b8a1d 248 SUPERFAMILY SSF51735 3 247 4.81E-74 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS12800 0d3188eae05ea30b3f62f6ef0a1b8a1d 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 247 2.9E-60 T 29-03-2018 CDC59_RS12800 0d3188eae05ea30b3f62f6ef0a1b8a1d 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 6.2E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS12800 0d3188eae05ea30b3f62f6ef0a1b8a1d 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 6.2E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS12800 0d3188eae05ea30b3f62f6ef0a1b8a1d 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 6.2E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS12800 0d3188eae05ea30b3f62f6ef0a1b8a1d 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 6.2E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS12800 0d3188eae05ea30b3f62f6ef0a1b8a1d 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 6.2E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS12800 0d3188eae05ea30b3f62f6ef0a1b8a1d 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 6.2E-38 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS12800 0d3188eae05ea30b3f62f6ef0a1b8a1d 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 1.8E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS12800 0d3188eae05ea30b3f62f6ef0a1b8a1d 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 1.8E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS12800 0d3188eae05ea30b3f62f6ef0a1b8a1d 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 1.8E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS12800 0d3188eae05ea30b3f62f6ef0a1b8a1d 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CDC59_RS12800 0d3188eae05ea30b3f62f6ef0a1b8a1d 248 Gene3D G3DSA:3.40.50.720 37 248 3.7E-62 T 29-03-2018 CDC59_RS12800 0d3188eae05ea30b3f62f6ef0a1b8a1d 248 Gene3D G3DSA:3.40.50.720 1 36 7.2E-7 T 29-03-2018 CDC59_RS10505 19ff0c384f8bff59b78beffb686d487a 857 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 360 483 5.4E-29 T 29-03-2018 IPR000014 PAS domain CDC59_RS10505 19ff0c384f8bff59b78beffb686d487a 857 Pfam PF00989 PAS fold 361 473 2.5E-17 T 29-03-2018 IPR013767 PAS fold GO:0006355 CDC59_RS10505 19ff0c384f8bff59b78beffb686d487a 857 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 741 854 7.4E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS10505 19ff0c384f8bff59b78beffb686d487a 857 Gene3D G3DSA:3.30.565.10 659 855 7.3E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS10505 19ff0c384f8bff59b78beffb686d487a 857 SUPERFAMILY SSF55785 473 604 1.05E-8 T 29-03-2018 IPR000014 PAS domain CDC59_RS10505 19ff0c384f8bff59b78beffb686d487a 857 SUPERFAMILY SSF55874 687 854 1.07E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS10505 19ff0c384f8bff59b78beffb686d487a 857 SUPERFAMILY SSF55785 347 474 7.33E-26 T 29-03-2018 IPR000014 PAS domain CDC59_RS10505 19ff0c384f8bff59b78beffb686d487a 857 SUPERFAMILY SSF47384 621 696 3.92E-7 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS10505 19ff0c384f8bff59b78beffb686d487a 857 Gene3D G3DSA:3.30.450.20 486 658 2.0E-15 T 29-03-2018 CDC59_RS10505 19ff0c384f8bff59b78beffb686d487a 857 SMART SM00388 628 698 3.1E-4 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS10505 19ff0c384f8bff59b78beffb686d487a 857 SMART SM00086 434 476 2.1E-7 T 29-03-2018 IPR001610 PAC motif CDC59_RS10505 19ff0c384f8bff59b78beffb686d487a 857 Gene3D G3DSA:3.30.450.20 349 485 9.9E-29 T 29-03-2018 CDC59_RS10505 19ff0c384f8bff59b78beffb686d487a 857 PRINTS PR00344 Bacterial sensor protein C-terminal signature 786 800 2.4E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS10505 19ff0c384f8bff59b78beffb686d487a 857 PRINTS PR00344 Bacterial sensor protein C-terminal signature 804 814 2.4E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS10505 19ff0c384f8bff59b78beffb686d487a 857 PRINTS PR00344 Bacterial sensor protein C-terminal signature 815 833 2.4E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS10505 19ff0c384f8bff59b78beffb686d487a 857 PRINTS PR00344 Bacterial sensor protein C-terminal signature 840 853 2.4E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS10505 19ff0c384f8bff59b78beffb686d487a 857 SMART SM00091 360 427 7.6E-10 T 29-03-2018 IPR000014 PAS domain CDC59_RS10505 19ff0c384f8bff59b78beffb686d487a 857 SMART SM00091 488 558 79.0 T 29-03-2018 IPR000014 PAS domain CDC59_RS10505 19ff0c384f8bff59b78beffb686d487a 857 Pfam PF13188 PAS domain 489 532 0.006 T 29-03-2018 IPR000014 PAS domain CDC59_RS10505 19ff0c384f8bff59b78beffb686d487a 857 SMART SM00387 740 856 1.6E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS06090 e72a03e4e943b3a214117f7175feea73 293 Pfam PF01738 Dienelactone hydrolase family 64 290 9.0E-61 T 29-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 CDC59_RS06090 e72a03e4e943b3a214117f7175feea73 293 SUPERFAMILY SSF53474 53 290 3.54E-47 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS06090 e72a03e4e943b3a214117f7175feea73 293 Gene3D G3DSA:3.40.50.1820 47 290 1.5E-39 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS12815 3df87e181c26ba34c3c13e4906c3f0d7 310 SUPERFAMILY SSF103481 38 139 6.8E-16 T 29-03-2018 CDC59_RS12815 3df87e181c26ba34c3c13e4906c3f0d7 310 Pfam PF00892 EamA-like transporter family 9 136 3.9E-22 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CDC59_RS12815 3df87e181c26ba34c3c13e4906c3f0d7 310 Pfam PF00892 EamA-like transporter family 150 281 5.2E-20 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CDC59_RS12815 3df87e181c26ba34c3c13e4906c3f0d7 310 SUPERFAMILY SSF103481 186 280 4.71E-17 T 29-03-2018 CDC59_RS14270 33520492b349d5e68cca200d08268be9 382 Pfam PF00633 Helix-hairpin-helix motif 119 147 6.5E-8 T 29-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 CDC59_RS14270 33520492b349d5e68cca200d08268be9 382 SMART SM00478 58 210 5.2E-48 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CDC59_RS14270 33520492b349d5e68cca200d08268be9 382 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 25 292 4.1E-101 T 29-03-2018 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 CDC59_RS14270 33520492b349d5e68cca200d08268be9 382 Gene3D G3DSA:3.90.79.10 249 380 8.2E-16 T 29-03-2018 CDC59_RS14270 33520492b349d5e68cca200d08268be9 382 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 55 186 4.0E-21 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CDC59_RS14270 33520492b349d5e68cca200d08268be9 382 SUPERFAMILY SSF55811 244 376 9.92E-26 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CDC59_RS14270 33520492b349d5e68cca200d08268be9 382 Pfam PF14815 NUDIX domain 261 374 2.3E-24 T 29-03-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CDC59_RS14270 33520492b349d5e68cca200d08268be9 382 ProSitePatterns PS01155 Endonuclease III family signature. 121 150 - T 29-03-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 CDC59_RS14270 33520492b349d5e68cca200d08268be9 382 SUPERFAMILY SSF48150 23 248 1.3E-69 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CDC59_RS14270 33520492b349d5e68cca200d08268be9 382 Gene3D G3DSA:1.10.340.30 40 136 2.9E-34 T 29-03-2018 CDC59_RS14270 33520492b349d5e68cca200d08268be9 382 Gene3D G3DSA:1.10.1670.10 137 248 1.9E-29 T 29-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CDC59_RS22250 88d56a128fbaa2883ebb8040915e542a 178 TIGRFAM TIGR02523 type_IV_pilV: type IV pilus modification protein PilV 8 133 9.4E-17 T 29-03-2018 IPR013362 Pilus modification type IV, PilV CDC59_RS22250 88d56a128fbaa2883ebb8040915e542a 178 Pfam PF07963 Prokaryotic N-terminal methylation motif 5 30 2.1E-5 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS20970 cad02fed004cd7a90e02276d9d272fc8 293 Pfam PF00487 Fatty acid desaturase 23 254 3.6E-25 T 29-03-2018 IPR005804 Fatty acid desaturase domain GO:0006629 CDC59_RS06975 0a52a21e5c9f0b18762606a739908438 213 SUPERFAMILY SSF52833 1 91 1.12E-21 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS06975 0a52a21e5c9f0b18762606a739908438 213 Gene3D G3DSA:1.20.1050.10 97 211 2.3E-26 T 29-03-2018 CDC59_RS06975 0a52a21e5c9f0b18762606a739908438 213 Pfam PF00043 Glutathione S-transferase, C-terminal domain 117 198 2.8E-6 T 29-03-2018 IPR004046 Glutathione S-transferase, C-terminal CDC59_RS06975 0a52a21e5c9f0b18762606a739908438 213 SUPERFAMILY SSF47616 86 209 3.9E-31 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like CDC59_RS06975 0a52a21e5c9f0b18762606a739908438 213 Gene3D G3DSA:3.40.30.10 1 96 3.6E-24 T 29-03-2018 CDC59_RS06975 0a52a21e5c9f0b18762606a739908438 213 Pfam PF13417 Glutathione S-transferase, N-terminal domain 8 85 2.3E-12 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CDC59_RS03405 dcaab6bb096cb3329a838926d36d7075 166 ProSitePatterns PS01265 Tpx family signature. 83 94 - T 29-03-2018 IPR018219 Thiol peroxidase conserved site GO:0016684|GO:0055114 CDC59_RS03405 dcaab6bb096cb3329a838926d36d7075 166 Pfam PF08534 Redoxin 20 162 2.8E-27 T 29-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 CDC59_RS03405 dcaab6bb096cb3329a838926d36d7075 166 Gene3D G3DSA:3.40.30.10 13 166 3.1E-24 T 29-03-2018 CDC59_RS03405 dcaab6bb096cb3329a838926d36d7075 166 Hamap MF_00269 Probable thiol peroxidase [tpx]. 3 166 39.923 T 29-03-2018 IPR002065 Putative thiol peroxidase Tpx GO:0008379|GO:0016209|GO:0055114 CDC59_RS03405 dcaab6bb096cb3329a838926d36d7075 166 SUPERFAMILY SSF52833 1 163 6.48E-44 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS16375 2717ab1d5b3df26f33274cc681e60132 298 TIGRFAM TIGR02317 prpB: methylisocitrate lyase 12 295 3.9E-126 T 29-03-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 CDC59_RS16375 2717ab1d5b3df26f33274cc681e60132 298 Hamap MF_01939 2-methylisocitrate lyase [prpB]. 9 296 49.831 T 29-03-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 CDC59_RS16375 2717ab1d5b3df26f33274cc681e60132 298 Gene3D G3DSA:3.20.20.60 8 298 1.0E-90 T 29-03-2018 CDC59_RS16375 2717ab1d5b3df26f33274cc681e60132 298 Pfam PF13714 Phosphoenolpyruvate phosphomutase 16 257 5.5E-51 T 29-03-2018 CDC59_RS16375 2717ab1d5b3df26f33274cc681e60132 298 ProSitePatterns PS00161 Isocitrate lyase signature. 125 130 - T 29-03-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 CDC59_RS16375 2717ab1d5b3df26f33274cc681e60132 298 SUPERFAMILY SSF51621 7 294 2.42E-99 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CDC59_RS07735 7f46eec10a48aa71bcbd4296728f9689 375 SUPERFAMILY SSF51735 8 158 1.62E-13 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS07735 7f46eec10a48aa71bcbd4296728f9689 375 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 11 138 3.1E-16 T 29-03-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 CDC59_RS07735 7f46eec10a48aa71bcbd4296728f9689 375 Gene3D G3DSA:3.40.50.720 2 157 8.2E-18 T 29-03-2018 CDC59_RS07120 6696713980716d2a29c12aa5d09d003c 347 Pfam PF13377 Periplasmic binding protein-like domain 168 337 2.6E-40 T 29-03-2018 CDC59_RS07120 6696713980716d2a29c12aa5d09d003c 347 Gene3D G3DSA:3.40.50.2300 167 340 1.1E-54 T 29-03-2018 CDC59_RS07120 6696713980716d2a29c12aa5d09d003c 347 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 2.0E-5 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDC59_RS07120 6696713980716d2a29c12aa5d09d003c 347 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 2.0E-5 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDC59_RS07120 6696713980716d2a29c12aa5d09d003c 347 Gene3D G3DSA:1.10.260.40 2 57 1.2E-20 T 29-03-2018 CDC59_RS07120 6696713980716d2a29c12aa5d09d003c 347 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 1.3E-17 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDC59_RS07120 6696713980716d2a29c12aa5d09d003c 347 SUPERFAMILY SSF53822 60 340 2.36E-91 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CDC59_RS07120 6696713980716d2a29c12aa5d09d003c 347 SMART SM00354 1 71 1.2E-31 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDC59_RS07120 6696713980716d2a29c12aa5d09d003c 347 SUPERFAMILY SSF47413 1 59 2.13E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDC59_RS07120 6696713980716d2a29c12aa5d09d003c 347 Gene3D G3DSA:3.40.50.2300 58 166 2.0E-41 T 29-03-2018 CDC59_RS07120 6696713980716d2a29c12aa5d09d003c 347 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 29-03-2018 CDC59_RS14310 daa5e83d844827d592f3a53faf0a4688 203 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 98 186 9.1E-32 T 29-03-2018 IPR020057 Ribosomal protein L25, beta domain CDC59_RS14310 daa5e83d844827d592f3a53faf0a4688 203 Hamap MF_01336 50S ribosomal protein L25 [rplY]. 1 93 21.765 T 29-03-2018 IPR020055 Ribosomal protein L25, short-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 CDC59_RS14310 daa5e83d844827d592f3a53faf0a4688 203 Gene3D G3DSA:2.170.120.20 97 191 3.9E-32 T 29-03-2018 IPR020057 Ribosomal protein L25, beta domain CDC59_RS14310 daa5e83d844827d592f3a53faf0a4688 203 Gene3D G3DSA:2.40.240.10 1 93 1.6E-28 T 29-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CDC59_RS14310 daa5e83d844827d592f3a53faf0a4688 203 SUPERFAMILY SSF50715 2 191 5.41E-57 T 29-03-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CDC59_RS14310 daa5e83d844827d592f3a53faf0a4688 203 Pfam PF01386 Ribosomal L25p family 5 90 9.9E-24 T 29-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 CDC59_RS14310 daa5e83d844827d592f3a53faf0a4688 203 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 1 184 32.111 T 29-03-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 CDC59_RS14310 daa5e83d844827d592f3a53faf0a4688 203 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 6 172 5.2E-45 T 29-03-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 CDC59_RS14310 daa5e83d844827d592f3a53faf0a4688 203 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 1 93 1.0E-46 T 29-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 CDC59_RS20190 96b763ad241f9fe14dc72d9ce00fee5a 197 TIGRFAM TIGR02557 HpaP: type III secretion protein HpaP 1 197 3.6E-69 T 29-03-2018 IPR013390 Type III secretion protein HpaP CDC59_RS20190 96b763ad241f9fe14dc72d9ce00fee5a 197 Pfam PF09483 Type III secretion protein (HpaP) 14 197 9.8E-55 T 29-03-2018 IPR013390 Type III secretion protein HpaP CDC59_RS05580 450cb93ba0e3643800a3f62951370a4b 202 Pfam PF01555 DNA methylase 130 199 2.9E-9 T 29-03-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 CDC59_RS05580 450cb93ba0e3643800a3f62951370a4b 202 Gene3D G3DSA:3.40.50.150 1 202 4.2E-20 T 29-03-2018 CDC59_RS05580 450cb93ba0e3643800a3f62951370a4b 202 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 14 28 3.3E-11 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CDC59_RS05580 450cb93ba0e3643800a3f62951370a4b 202 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 169 187 3.3E-11 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CDC59_RS05580 450cb93ba0e3643800a3f62951370a4b 202 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 150 167 3.3E-11 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CDC59_RS05580 450cb93ba0e3643800a3f62951370a4b 202 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 57 77 3.3E-11 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CDC59_RS05580 450cb93ba0e3643800a3f62951370a4b 202 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 192 202 3.3E-11 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CDC59_RS05580 450cb93ba0e3643800a3f62951370a4b 202 SUPERFAMILY SSF53335 2 199 2.21E-27 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS02450 db6ca6f1a6a24415d4c18bc4621266b7 802 Pfam PF00905 Penicillin binding protein transpeptidase domain 445 690 3.8E-38 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CDC59_RS02450 db6ca6f1a6a24415d4c18bc4621266b7 802 Gene3D G3DSA:1.10.3810.10 69 262 2.8E-78 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 CDC59_RS02450 db6ca6f1a6a24415d4c18bc4621266b7 802 SUPERFAMILY SSF56601 438 755 2.29E-122 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CDC59_RS02450 db6ca6f1a6a24415d4c18bc4621266b7 802 SUPERFAMILY SSF56601 231 253 2.29E-122 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CDC59_RS02450 db6ca6f1a6a24415d4c18bc4621266b7 802 SUPERFAMILY SSF56601 282 333 2.29E-122 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CDC59_RS02450 db6ca6f1a6a24415d4c18bc4621266b7 802 Pfam PF00912 Transglycosylase 77 249 6.4E-63 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 CDC59_RS02450 db6ca6f1a6a24415d4c18bc4621266b7 802 SUPERFAMILY SSF53955 63 271 5.91E-75 T 29-03-2018 IPR023346 Lysozyme-like domain CDC59_RS02450 db6ca6f1a6a24415d4c18bc4621266b7 802 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 86 728 8.7E-189 T 29-03-2018 CDC59_RS02450 db6ca6f1a6a24415d4c18bc4621266b7 802 Pfam PF17092 Penicillin-binding protein OB-like domain 336 441 1.3E-22 T 29-03-2018 IPR031376 Penicillin-binding protein, OB-like domain CDC59_RS02450 db6ca6f1a6a24415d4c18bc4621266b7 802 Gene3D G3DSA:3.40.710.10 263 742 1.2E-121 T 29-03-2018 CDC59_RS15575 ff79bc348426355d14cfee700648ea49 173 Gene3D G3DSA:3.90.1340.10 1 54 3.7E-20 T 29-03-2018 IPR011083 Phage tail collar domain CDC59_RS15575 ff79bc348426355d14cfee700648ea49 173 Pfam PF07484 Phage Tail Collar Domain 7 63 1.2E-24 T 29-03-2018 IPR011083 Phage tail collar domain CDC59_RS15575 ff79bc348426355d14cfee700648ea49 173 Gene3D G3DSA:4.10.1070.10 55 155 2.8E-5 T 29-03-2018 CDC59_RS15575 ff79bc348426355d14cfee700648ea49 173 SUPERFAMILY SSF88874 1 167 2.88E-44 T 29-03-2018 CDC59_RS19950 29aefb4b73442cc2eb68daf525a3e918 215 Gene3D G3DSA:1.10.10.60 1 35 7.4E-15 T 29-03-2018 CDC59_RS19950 29aefb4b73442cc2eb68daf525a3e918 215 ProSitePatterns PS01081 TetR-type HTH domain signature. 13 44 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CDC59_RS19950 29aefb4b73442cc2eb68daf525a3e918 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 2 47 2.1E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDC59_RS19950 29aefb4b73442cc2eb68daf525a3e918 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 45 7.4E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDC59_RS19950 29aefb4b73442cc2eb68daf525a3e918 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 1 14 7.4E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDC59_RS19950 29aefb4b73442cc2eb68daf525a3e918 215 Gene3D G3DSA:1.10.10.60 36 142 1.9E-8 T 29-03-2018 CDC59_RS19950 29aefb4b73442cc2eb68daf525a3e918 215 SUPERFAMILY SSF46689 2 49 7.18E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS19950 29aefb4b73442cc2eb68daf525a3e918 215 SUPERFAMILY SSF48498 68 163 1.51E-6 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CDC59_RS16865 a786969066467928872ea21a803acce8 360 Pfam PF00512 His Kinase A (phospho-acceptor) domain 140 198 1.5E-7 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS16865 a786969066467928872ea21a803acce8 360 SMART SM00388 134 198 1.1E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS16865 a786969066467928872ea21a803acce8 360 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 243 351 2.7E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS16865 a786969066467928872ea21a803acce8 360 Gene3D G3DSA:1.10.287.130 117 181 6.1E-8 T 29-03-2018 CDC59_RS16865 a786969066467928872ea21a803acce8 360 SMART SM00387 242 353 2.1E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS16865 a786969066467928872ea21a803acce8 360 Gene3D G3DSA:3.30.565.10 182 351 4.2E-39 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS16865 a786969066467928872ea21a803acce8 360 SMART SM00304 79 133 2.5E-5 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CDC59_RS16865 a786969066467928872ea21a803acce8 360 PRINTS PR00344 Bacterial sensor protein C-terminal signature 337 350 2.1E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS16865 a786969066467928872ea21a803acce8 360 PRINTS PR00344 Bacterial sensor protein C-terminal signature 278 292 2.1E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS16865 a786969066467928872ea21a803acce8 360 PRINTS PR00344 Bacterial sensor protein C-terminal signature 313 331 2.1E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS16865 a786969066467928872ea21a803acce8 360 PRINTS PR00344 Bacterial sensor protein C-terminal signature 296 306 2.1E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS16865 a786969066467928872ea21a803acce8 360 SUPERFAMILY SSF55874 188 351 5.24E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS16865 a786969066467928872ea21a803acce8 360 SUPERFAMILY SSF47384 117 199 1.14E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS06100 2b375dae8324d0784cf2022a3172f194 296 Gene3D G3DSA:3.40.250.10 2 154 2.6E-28 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS06100 2b375dae8324d0784cf2022a3172f194 296 SUPERFAMILY SSF52821 7 145 2.1E-38 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS06100 2b375dae8324d0784cf2022a3172f194 296 Pfam PF00581 Rhodanese-like domain 169 284 6.8E-9 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS06100 2b375dae8324d0784cf2022a3172f194 296 Pfam PF00581 Rhodanese-like domain 26 136 1.5E-13 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS06100 2b375dae8324d0784cf2022a3172f194 296 Gene3D G3DSA:3.40.250.10 170 296 3.3E-21 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS06100 2b375dae8324d0784cf2022a3172f194 296 ProSitePatterns PS00683 Rhodanese C-terminal signature. 272 282 - T 29-03-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 CDC59_RS06100 2b375dae8324d0784cf2022a3172f194 296 SUPERFAMILY SSF52821 171 295 1.44E-30 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS06100 2b375dae8324d0784cf2022a3172f194 296 SMART SM00450 168 288 8.8E-11 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS06100 2b375dae8324d0784cf2022a3172f194 296 SMART SM00450 14 140 1.3E-17 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS21515 ee43b4bf3dca17f881782b7ac0e9cdc0 430 SMART SM00421 347 404 8.7E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS21515 ee43b4bf3dca17f881782b7ac0e9cdc0 430 Gene3D G3DSA:1.10.10.10 329 406 5.7E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS21515 ee43b4bf3dca17f881782b7ac0e9cdc0 430 Gene3D G3DSA:3.30.450.20 175 317 4.5E-4 T 29-03-2018 CDC59_RS21515 ee43b4bf3dca17f881782b7ac0e9cdc0 430 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 380 392 6.7E-5 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS21515 ee43b4bf3dca17f881782b7ac0e9cdc0 430 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 364 380 6.7E-5 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS21515 ee43b4bf3dca17f881782b7ac0e9cdc0 430 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 350 364 6.7E-5 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS21515 ee43b4bf3dca17f881782b7ac0e9cdc0 430 SUPERFAMILY SSF46894 340 406 2.79E-14 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CDC59_RS21515 ee43b4bf3dca17f881782b7ac0e9cdc0 430 Pfam PF00196 Bacterial regulatory proteins, luxR family 350 403 8.0E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS20510 b40a8fba218cf3079dac990ad474bc47 328 Pfam PF05598 Transposase domain (DUF772) 51 126 6.0E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS20510 b40a8fba218cf3079dac990ad474bc47 328 Pfam PF01609 Transposase DDE domain 138 312 2.4E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS11675 b40a8fba218cf3079dac990ad474bc47 328 Pfam PF05598 Transposase domain (DUF772) 51 126 6.0E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS11675 b40a8fba218cf3079dac990ad474bc47 328 Pfam PF01609 Transposase DDE domain 138 312 2.4E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS15940 b40a8fba218cf3079dac990ad474bc47 328 Pfam PF05598 Transposase domain (DUF772) 51 126 6.0E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS15940 b40a8fba218cf3079dac990ad474bc47 328 Pfam PF01609 Transposase DDE domain 138 312 2.4E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS09680 b40a8fba218cf3079dac990ad474bc47 328 Pfam PF05598 Transposase domain (DUF772) 51 126 6.0E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS09680 b40a8fba218cf3079dac990ad474bc47 328 Pfam PF01609 Transposase DDE domain 138 312 2.4E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS04330 e7b027db5fe0002f39d22bb04aaa5da9 397 Gene3D G3DSA:3.40.50.300 130 371 5.7E-43 T 29-03-2018 CDC59_RS04330 e7b027db5fe0002f39d22bb04aaa5da9 397 SUPERFAMILY SSF52540 132 370 1.02E-35 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS04330 e7b027db5fe0002f39d22bb04aaa5da9 397 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 136 344 9.2E-9 T 29-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CDC59_RS04330 e7b027db5fe0002f39d22bb04aaa5da9 397 SUPERFAMILY SSF52172 1 122 2.42E-12 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS04330 e7b027db5fe0002f39d22bb04aaa5da9 397 Gene3D G3DSA:3.40.50.2300 1 129 3.0E-10 T 29-03-2018 CDC59_RS04905 3d0de9ee11d33b8907ee53cfefbb5b38 212 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 171 212 5.9E-19 T 29-03-2018 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CDC59_RS04905 3d0de9ee11d33b8907ee53cfefbb5b38 212 PIRSF PIRSF000190 1 212 3.0E-83 T 29-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CDC59_RS04905 3d0de9ee11d33b8907ee53cfefbb5b38 212 SUPERFAMILY SSF50475 7 212 4.86E-71 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CDC59_RS04905 3d0de9ee11d33b8907ee53cfefbb5b38 212 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 3 212 6.5E-87 T 29-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CDC59_RS04905 3d0de9ee11d33b8907ee53cfefbb5b38 212 Gene3D G3DSA:2.30.110.10 11 212 1.9E-75 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CDC59_RS04905 3d0de9ee11d33b8907ee53cfefbb5b38 212 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 10 212 40.559 T 29-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CDC59_RS04905 3d0de9ee11d33b8907ee53cfefbb5b38 212 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 181 194 - T 29-03-2018 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CDC59_RS04905 3d0de9ee11d33b8907ee53cfefbb5b38 212 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 33 119 4.7E-29 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CDC59_RS16190 9aec54c8a113688ebffc22df008cc6b8 283 Gene3D G3DSA:3.90.226.10 25 240 1.4E-55 T 29-03-2018 CDC59_RS16190 9aec54c8a113688ebffc22df008cc6b8 283 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 123 143 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CDC59_RS16190 9aec54c8a113688ebffc22df008cc6b8 283 Gene3D G3DSA:1.10.12.10 241 282 1.0E-10 T 29-03-2018 IPR014748 Crontonase, C-terminal CDC59_RS16190 9aec54c8a113688ebffc22df008cc6b8 283 Pfam PF00378 Enoyl-CoA hydratase/isomerase 30 282 3.4E-41 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CDC59_RS16190 9aec54c8a113688ebffc22df008cc6b8 283 SUPERFAMILY SSF52096 20 282 2.02E-72 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CDC59_RS02425 1d50a4c609280ee7dd357ed2c9766a3c 330 Pfam PF00174 Oxidoreductase molybdopterin binding domain 105 260 9.7E-31 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CDC59_RS02425 1d50a4c609280ee7dd357ed2c9766a3c 330 Hamap MF_01206 Protein-methionine-sulfoxide reductase catalytic subunit MsrP [msrP]. 12 330 55.874 T 29-03-2018 IPR022867 Protein-methionine-sulfoxide reductase subunit MsrP GO:0016667|GO:0030091|GO:0043546|GO:0055114 CDC59_RS02425 1d50a4c609280ee7dd357ed2c9766a3c 330 Gene3D G3DSA:3.90.420.10 37 285 1.3E-61 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CDC59_RS02425 1d50a4c609280ee7dd357ed2c9766a3c 330 SUPERFAMILY SSF56524 70 326 5.89E-89 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CDC59_RS16040 dcac30879f28c9d5b81181d5fc842b26 244 SMART SM00382 29 238 9.5E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS16040 dcac30879f28c9d5b81181d5fc842b26 244 SUPERFAMILY SSF52540 4 242 1.22E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS16040 dcac30879f28c9d5b81181d5fc842b26 244 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS16040 dcac30879f28c9d5b81181d5fc842b26 244 Gene3D G3DSA:3.40.50.300 1 242 2.0E-53 T 29-03-2018 CDC59_RS16040 dcac30879f28c9d5b81181d5fc842b26 244 Pfam PF00005 ABC transporter 21 172 5.5E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS02280 c1c5d4c23f503173ee627b583013d2a3 89 Pfam PF00366 Ribosomal protein S17 14 80 8.0E-32 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS02280 c1c5d4c23f503173ee627b583013d2a3 89 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 9 79 6.0E-36 T 29-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS02280 c1c5d4c23f503173ee627b583013d2a3 89 PRINTS PR00973 Ribosomal protein S17 family signature 70 77 5.1E-13 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS02280 c1c5d4c23f503173ee627b583013d2a3 89 PRINTS PR00973 Ribosomal protein S17 family signature 60 70 5.1E-13 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS02280 c1c5d4c23f503173ee627b583013d2a3 89 PRINTS PR00973 Ribosomal protein S17 family signature 28 51 5.1E-13 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS02280 c1c5d4c23f503173ee627b583013d2a3 89 Gene3D G3DSA:2.40.50.140 8 89 6.5E-30 T 29-03-2018 CDC59_RS02280 c1c5d4c23f503173ee627b583013d2a3 89 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 9 84 24.693 T 29-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS02280 c1c5d4c23f503173ee627b583013d2a3 89 SUPERFAMILY SSF50249 9 87 1.24E-31 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDC59_RS02280 c1c5d4c23f503173ee627b583013d2a3 89 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 9 79 3.0E-34 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS02280 c1c5d4c23f503173ee627b583013d2a3 89 ProSitePatterns PS00056 Ribosomal protein S17 signature. 60 72 - T 29-03-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS08220 58f6ae2911990b0f7d5125cebf052d47 194 Gene3D G3DSA:3.40.50.2020 2 182 1.3E-23 T 29-03-2018 CDC59_RS08220 58f6ae2911990b0f7d5125cebf052d47 194 Pfam PF00156 Phosphoribosyl transferase domain 15 161 2.1E-25 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CDC59_RS08220 58f6ae2911990b0f7d5125cebf052d47 194 SUPERFAMILY SSF53271 6 176 2.7E-36 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CDC59_RS08795 6cd9485eff18a8f8bfbbebc88abf55c6 126 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 6 123 17.298 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CDC59_RS08795 6cd9485eff18a8f8bfbbebc88abf55c6 126 TIGRFAM TIGR00494 crcB: protein CrcB 8 120 8.4E-25 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CDC59_RS08795 6cd9485eff18a8f8bfbbebc88abf55c6 126 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 8 118 1.1E-19 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CDC59_RS13690 24814ff4979970f783bd12ce9d10c110 411 TIGRFAM TIGR01984 UbiH: 2-polyprenyl-6-methoxyphenol 4-hydroxylase 12 407 2.9E-134 T 29-03-2018 IPR011295 2-polyprenyl-6-methoxyphenol 4-hydroxylase GO:0006744|GO:0008681 CDC59_RS13690 24814ff4979970f783bd12ce9d10c110 411 SUPERFAMILY SSF51905 10 194 4.9E-34 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS13690 24814ff4979970f783bd12ce9d10c110 411 SUPERFAMILY SSF51905 300 406 4.9E-34 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS13690 24814ff4979970f783bd12ce9d10c110 411 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 12 406 1.2E-108 T 29-03-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 CDC59_RS13690 24814ff4979970f783bd12ce9d10c110 411 Gene3D G3DSA:3.50.50.60 7 340 1.1E-27 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS13690 24814ff4979970f783bd12ce9d10c110 411 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 12 34 3.1E-14 T 29-03-2018 CDC59_RS13690 24814ff4979970f783bd12ce9d10c110 411 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 142 157 3.1E-14 T 29-03-2018 CDC59_RS13690 24814ff4979970f783bd12ce9d10c110 411 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 319 335 3.1E-14 T 29-03-2018 CDC59_RS13690 24814ff4979970f783bd12ce9d10c110 411 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 304 319 3.1E-14 T 29-03-2018 CDC59_RS13690 24814ff4979970f783bd12ce9d10c110 411 Pfam PF01494 FAD binding domain 11 344 4.2E-16 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 CDC59_RS13690 24814ff4979970f783bd12ce9d10c110 411 ProSitePatterns PS01304 ubiH/COQ6 monooxygenase family signature. 318 331 - T 29-03-2018 IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site GO:0016709|GO:0055114 Reactome: R-HSA-2142789 CDC59_RS16385 7654dbcbee22ca4f554b1d608e5fd101 109 PIRSF PIRSF039032 3 107 4.3E-31 T 29-03-2018 IPR009387 Toxin HigB-2 CDC59_RS07130 7915588a44b052e80467b3468fa2cfb0 523 ProSitePatterns PS00211 ABC transporters family signature. 409 423 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS07130 7915588a44b052e80467b3468fa2cfb0 523 SUPERFAMILY SSF52540 276 490 4.25E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS07130 7915588a44b052e80467b3468fa2cfb0 523 SMART SM00382 289 485 0.0016 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS07130 7915588a44b052e80467b3468fa2cfb0 523 SMART SM00382 35 223 8.0E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS07130 7915588a44b052e80467b3468fa2cfb0 523 Pfam PF00005 ABC transporter 281 436 4.3E-17 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS07130 7915588a44b052e80467b3468fa2cfb0 523 Pfam PF00005 ABC transporter 26 175 8.8E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS07130 7915588a44b052e80467b3468fa2cfb0 523 Gene3D G3DSA:3.40.50.300 271 493 3.0E-37 T 29-03-2018 CDC59_RS07130 7915588a44b052e80467b3468fa2cfb0 523 Gene3D G3DSA:3.40.50.300 8 261 7.0E-52 T 29-03-2018 CDC59_RS07130 7915588a44b052e80467b3468fa2cfb0 523 SUPERFAMILY SSF52540 10 236 2.48E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS11465 ac203935eccc1717422a6f62a7c61a0b 233 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 5 108 7.1E-33 T 29-03-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CDC59_RS11465 ac203935eccc1717422a6f62a7c61a0b 233 Pfam PF13534 4Fe-4S dicluster domain 143 216 1.2E-9 T 29-03-2018 CDC59_RS11465 ac203935eccc1717422a6f62a7c61a0b 233 SUPERFAMILY SSF46548 103 230 6.8E-39 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CDC59_RS11465 ac203935eccc1717422a6f62a7c61a0b 233 Gene3D G3DSA:3.10.20.30 1 102 9.2E-32 T 29-03-2018 IPR012675 Beta-grasp domain CDC59_RS11465 ac203935eccc1717422a6f62a7c61a0b 233 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 144 155 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CDC59_RS11465 ac203935eccc1717422a6f62a7c61a0b 233 SUPERFAMILY SSF54292 2 102 2.71E-28 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CDC59_RS11465 ac203935eccc1717422a6f62a7c61a0b 233 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 7 225 5.0E-85 T 29-03-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CDC59_RS11465 ac203935eccc1717422a6f62a7c61a0b 233 Gene3D G3DSA:1.10.1060.10 103 233 3.2E-31 T 29-03-2018 CDC59_RS12070 1c9e50014620371ea79bc3a408476ad7 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 1.1E-78 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CDC59_RS12070 1c9e50014620371ea79bc3a408476ad7 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 142 166 1.1E-78 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CDC59_RS12070 1c9e50014620371ea79bc3a408476ad7 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 127 139 1.1E-78 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CDC59_RS12070 1c9e50014620371ea79bc3a408476ad7 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 197 213 1.1E-78 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CDC59_RS12070 1c9e50014620371ea79bc3a408476ad7 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 243 264 1.1E-78 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CDC59_RS12070 1c9e50014620371ea79bc3a408476ad7 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 39 54 1.1E-78 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CDC59_RS12070 1c9e50014620371ea79bc3a408476ad7 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 282 300 1.1E-78 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CDC59_RS12070 1c9e50014620371ea79bc3a408476ad7 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 105 113 1.1E-78 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CDC59_RS12070 1c9e50014620371ea79bc3a408476ad7 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 60 70 1.1E-78 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CDC59_RS12070 1c9e50014620371ea79bc3a408476ad7 323 SUPERFAMILY SSF51905 1 320 2.16E-53 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS12070 1c9e50014620371ea79bc3a408476ad7 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 272 294 7.7E-41 T 29-03-2018 CDC59_RS12070 1c9e50014620371ea79bc3a408476ad7 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 146 164 7.7E-41 T 29-03-2018 CDC59_RS12070 1c9e50014620371ea79bc3a408476ad7 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 7.7E-41 T 29-03-2018 CDC59_RS12070 1c9e50014620371ea79bc3a408476ad7 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 241 257 7.7E-41 T 29-03-2018 CDC59_RS12070 1c9e50014620371ea79bc3a408476ad7 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 7.7E-41 T 29-03-2018 CDC59_RS12070 1c9e50014620371ea79bc3a408476ad7 323 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 134 154 - T 29-03-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 CDC59_RS12070 1c9e50014620371ea79bc3a408476ad7 323 Gene3D G3DSA:3.50.50.60 267 323 1.1E-7 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS12070 1c9e50014620371ea79bc3a408476ad7 323 Gene3D G3DSA:3.50.50.60 1 145 6.1E-20 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS12070 1c9e50014620371ea79bc3a408476ad7 323 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 6 319 2.8E-116 T 29-03-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 CDC59_RS12070 1c9e50014620371ea79bc3a408476ad7 323 Gene3D G3DSA:3.40.50.720 146 266 1.5E-22 T 29-03-2018 CDC59_RS12070 1c9e50014620371ea79bc3a408476ad7 323 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 307 2.1E-47 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS02235 e28cda5bfff16a5b47955e32de7b0902 220 ProSitePatterns PS00474 Ribosomal protein L3 signature. 104 127 - T 29-03-2018 IPR019926 Ribosomal protein L3, conserved site CDC59_RS02235 e28cda5bfff16a5b47955e32de7b0902 220 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 4 206 1.8E-86 T 29-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS02235 e28cda5bfff16a5b47955e32de7b0902 220 Gene3D G3DSA:4.10.960.10 58 168 2.3E-30 T 29-03-2018 CDC59_RS02235 e28cda5bfff16a5b47955e32de7b0902 220 SUPERFAMILY SSF50447 2 214 3.8E-79 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CDC59_RS02235 e28cda5bfff16a5b47955e32de7b0902 220 Pfam PF00297 Ribosomal protein L3 66 185 7.0E-16 T 29-03-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS02235 e28cda5bfff16a5b47955e32de7b0902 220 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 2 210 38.999 T 29-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS16585 3e322656b2b7f66bea996f472917544f 247 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 107 181 9.6E-11 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CDC59_RS16585 3e322656b2b7f66bea996f472917544f 247 SUPERFAMILY SSF56214 10 98 2.62E-18 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CDC59_RS16585 3e322656b2b7f66bea996f472917544f 247 Gene3D G3DSA:3.90.470.20 2 116 1.4E-20 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CDC59_RS16585 3e322656b2b7f66bea996f472917544f 247 SUPERFAMILY SSF56214 106 212 4.84E-18 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CDC59_RS16585 3e322656b2b7f66bea996f472917544f 247 Gene3D G3DSA:3.90.470.20 117 233 1.8E-8 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CDC59_RS12495 10110d9727c834c01df16944e0ec79c9 139 SMART SM00347 34 137 8.4E-4 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS12495 10110d9727c834c01df16944e0ec79c9 139 SUPERFAMILY SSF46785 6 131 4.07E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS12495 10110d9727c834c01df16944e0ec79c9 139 Gene3D G3DSA:1.10.10.10 3 138 4.9E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS12495 10110d9727c834c01df16944e0ec79c9 139 Pfam PF12802 MarR family 40 101 4.2E-14 T 29-03-2018 CDC59_RS05100 b9241463b82f3959818e5683d844b073 62 Gene3D G3DSA:3.30.429.10 1 62 1.5E-17 T 29-03-2018 CDC59_RS05100 b9241463b82f3959818e5683d844b073 62 SUPERFAMILY SSF55331 2 61 4.06E-19 T 29-03-2018 IPR014347 Tautomerase/MIF superfamily CDC59_RS05100 b9241463b82f3959818e5683d844b073 62 TIGRFAM TIGR00013 taut: 4-oxalocrotonate tautomerase family enzyme 1 59 2.9E-17 T 29-03-2018 IPR018191 4-oxalocrotonate tautomerase, Pseudomonas-type GO:0006725|GO:0016853 CDC59_RS05100 b9241463b82f3959818e5683d844b073 62 Pfam PF01361 Tautomerase enzyme 5 57 2.1E-14 T 29-03-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 CDC59_RS04290 bce46a70574c6a57b6605969d693bfad 412 Gene3D G3DSA:1.20.1250.20 199 412 3.2E-9 T 29-03-2018 CDC59_RS04290 bce46a70574c6a57b6605969d693bfad 412 Pfam PF07690 Major Facilitator Superfamily 28 350 2.0E-24 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDC59_RS04290 bce46a70574c6a57b6605969d693bfad 412 Gene3D G3DSA:1.20.1250.20 1 198 3.8E-19 T 29-03-2018 CDC59_RS04290 bce46a70574c6a57b6605969d693bfad 412 SUPERFAMILY SSF103473 20 392 1.7E-37 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS07110 ac46dc79f7bedba76bdbb6a668257686 693 Gene3D G3DSA:1.20.1080.10 334 593 1.0E-36 T 29-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CDC59_RS07110 ac46dc79f7bedba76bdbb6a668257686 693 Pfam PF10136 Site-specific recombinase 37 678 2.4E-234 T 29-03-2018 IPR011385 Putative site-specific recombinase Gcr CDC59_RS07110 ac46dc79f7bedba76bdbb6a668257686 693 PIRSF PIRSF015380 1 693 2.4E-280 T 29-03-2018 IPR011385 Putative site-specific recombinase Gcr CDC59_RS02865 bd29244c0124e7d74f5439660cbdc725 428 Pfam PF01494 FAD binding domain 16 377 2.0E-25 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 CDC59_RS02865 bd29244c0124e7d74f5439660cbdc725 428 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 16 428 5.1E-128 T 29-03-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 CDC59_RS02865 bd29244c0124e7d74f5439660cbdc725 428 ProSitePatterns PS01304 ubiH/COQ6 monooxygenase family signature. 333 346 - T 29-03-2018 IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site GO:0016709|GO:0055114 Reactome: R-HSA-2142789 CDC59_RS02865 bd29244c0124e7d74f5439660cbdc725 428 Gene3D G3DSA:3.50.50.60 12 356 4.2E-38 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS02865 bd29244c0124e7d74f5439660cbdc725 428 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 16 38 7.5E-20 T 29-03-2018 CDC59_RS02865 bd29244c0124e7d74f5439660cbdc725 428 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 175 190 7.5E-20 T 29-03-2018 CDC59_RS02865 bd29244c0124e7d74f5439660cbdc725 428 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 319 334 7.5E-20 T 29-03-2018 CDC59_RS02865 bd29244c0124e7d74f5439660cbdc725 428 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 334 350 7.5E-20 T 29-03-2018 CDC59_RS02865 bd29244c0124e7d74f5439660cbdc725 428 SUPERFAMILY SSF51905 15 196 3.06E-50 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS02865 bd29244c0124e7d74f5439660cbdc725 428 SUPERFAMILY SSF51905 306 423 3.06E-50 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS21005 fc160366088d824fc0cb287e6c2ae732 318 Gene3D G3DSA:1.10.3720.10 6 305 3.8E-37 T 29-03-2018 CDC59_RS21005 fc160366088d824fc0cb287e6c2ae732 318 SUPERFAMILY SSF161098 97 299 7.46E-18 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS21005 fc160366088d824fc0cb287e6c2ae732 318 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 316 3.9E-29 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS23700 2033d58154a39754f1718d8de460d54a 514 SUPERFAMILY SSF52540 261 489 3.14E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS23700 2033d58154a39754f1718d8de460d54a 514 TIGRFAM TIGR02633 xylG: D-xylose ABC transporter, ATP-binding protein 6 505 3.7E-257 T 29-03-2018 IPR013455 ABC transporter, D-xylose, ATP-binding protein GO:0005524|GO:0015614|GO:0015753|GO:0016020 CDC59_RS23700 2033d58154a39754f1718d8de460d54a 514 SUPERFAMILY SSF52540 6 233 2.71E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS23700 2033d58154a39754f1718d8de460d54a 514 SMART SM00382 290 485 5.6E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS23700 2033d58154a39754f1718d8de460d54a 514 SMART SM00382 31 231 5.1E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS23700 2033d58154a39754f1718d8de460d54a 514 Gene3D G3DSA:3.40.50.300 4 238 9.6E-53 T 29-03-2018 CDC59_RS23700 2033d58154a39754f1718d8de460d54a 514 Gene3D G3DSA:3.40.50.300 260 502 5.6E-32 T 29-03-2018 CDC59_RS23700 2033d58154a39754f1718d8de460d54a 514 Pfam PF00005 ABC transporter 22 175 2.6E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS23700 2033d58154a39754f1718d8de460d54a 514 Pfam PF00005 ABC transporter 282 436 2.4E-15 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS18335 4528a7e70d0429f3e312c51e947164db 1245 Gene3D G3DSA:3.30.2070.10 792 832 3.2E-4 T 29-03-2018 CDC59_RS18335 4528a7e70d0429f3e312c51e947164db 1245 Gene3D G3DSA:3.40.228.10 224 661 1.5E-97 T 29-03-2018 CDC59_RS18335 4528a7e70d0429f3e312c51e947164db 1245 Gene3D G3DSA:2.20.25.90 55 98 1.2E-28 T 29-03-2018 CDC59_RS18335 4528a7e70d0429f3e312c51e947164db 1245 Gene3D G3DSA:2.40.40.20 1046 1235 2.5E-45 T 29-03-2018 CDC59_RS18335 4528a7e70d0429f3e312c51e947164db 1245 SUPERFAMILY SSF50692 1078 1236 5.42E-45 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain CDC59_RS18335 4528a7e70d0429f3e312c51e947164db 1245 SMART SM00926 43 105 1.6E-8 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS18335 4528a7e70d0429f3e312c51e947164db 1245 TIGRFAM TIGR01580 narG: nitrate reductase, alpha subunit 2 1233 0.0 T 29-03-2018 IPR006468 Nitrate reductase, alpha subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.99.4 CDC59_RS18335 4528a7e70d0429f3e312c51e947164db 1245 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 48 66 - T 29-03-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 CDC59_RS18335 4528a7e70d0429f3e312c51e947164db 1245 Gene3D G3DSA:4.10.1200.10 1 26 5.2E-12 T 29-03-2018 CDC59_RS18335 4528a7e70d0429f3e312c51e947164db 1245 SUPERFAMILY SSF53706 4 1068 0.0 T 29-03-2018 CDC59_RS18335 4528a7e70d0429f3e312c51e947164db 1245 Gene3D G3DSA:3.40.50.740 108 212 3.3E-6 T 29-03-2018 CDC59_RS18335 4528a7e70d0429f3e312c51e947164db 1245 Pfam PF01568 Molydopterin dinucleotide binding domain 1086 1200 5.7E-21 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CDC59_RS18335 4528a7e70d0429f3e312c51e947164db 1245 Pfam PF00384 Molybdopterin oxidoreductase 108 830 1.1E-156 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS18335 4528a7e70d0429f3e312c51e947164db 1245 Pfam PF14710 Respiratory nitrate reductase alpha N-terminal 3 40 2.5E-15 T 29-03-2018 IPR028189 Nitrate reductase, alpha subunit, N-terminal KEGG: 00910+1.7.99.4 CDC59_RS04965 eb6861a10830fa306b3df65dac13536a 261 SUPERFAMILY SSF48403 70 257 9.83E-46 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CDC59_RS04965 eb6861a10830fa306b3df65dac13536a 261 Gene3D G3DSA:1.25.40.20 62 157 1.1E-25 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CDC59_RS04965 eb6861a10830fa306b3df65dac13536a 261 Gene3D G3DSA:1.25.40.20 158 259 1.7E-25 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CDC59_RS04965 eb6861a10830fa306b3df65dac13536a 261 Pfam PF12796 Ankyrin repeats (3 copies) 138 233 2.1E-13 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CDC59_RS04965 eb6861a10830fa306b3df65dac13536a 261 Pfam PF12796 Ankyrin repeats (3 copies) 70 129 1.4E-6 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CDC59_RS04965 eb6861a10830fa306b3df65dac13536a 261 SMART SM00248 197 231 0.14 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CDC59_RS04965 eb6861a10830fa306b3df65dac13536a 261 SMART SM00248 164 193 0.066 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CDC59_RS04965 eb6861a10830fa306b3df65dac13536a 261 SMART SM00248 131 160 1.9 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CDC59_RS04965 eb6861a10830fa306b3df65dac13536a 261 SMART SM00248 98 127 0.41 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CDC59_RS04965 eb6861a10830fa306b3df65dac13536a 261 PRINTS PR01415 Ankyrin repeat signature 165 180 7.3E-6 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CDC59_RS04965 eb6861a10830fa306b3df65dac13536a 261 PRINTS PR01415 Ankyrin repeat signature 218 232 7.3E-6 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CDC59_RS11470 4299db099ed0a535b1d4c9db782736a3 592 PIRSF PIRSF000171 3 583 6.9E-42 T 29-03-2018 CDC59_RS11470 4299db099ed0a535b1d4c9db782736a3 592 Pfam PF00890 FAD binding domain 14 409 1.4E-116 T 29-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CDC59_RS11470 4299db099ed0a535b1d4c9db782736a3 592 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 48 57 - T 29-03-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CDC59_RS11470 4299db099ed0a535b1d4c9db782736a3 592 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 387 394 2.5E-6 T 29-03-2018 CDC59_RS11470 4299db099ed0a535b1d4c9db782736a3 592 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 14 36 2.5E-6 T 29-03-2018 CDC59_RS11470 4299db099ed0a535b1d4c9db782736a3 592 Pfam PF02910 Fumarate reductase flavoprotein C-term 466 591 2.2E-39 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CDC59_RS11470 4299db099ed0a535b1d4c9db782736a3 592 Gene3D G3DSA:1.20.58.100 435 544 3.6E-31 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CDC59_RS11470 4299db099ed0a535b1d4c9db782736a3 592 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 14 591 2.3E-241 T 29-03-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CDC59_RS11470 4299db099ed0a535b1d4c9db782736a3 592 SUPERFAMILY SSF46977 456 592 1.22E-45 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CDC59_RS11470 4299db099ed0a535b1d4c9db782736a3 592 Gene3D G3DSA:4.10.80.40 545 592 5.1E-20 T 29-03-2018 CDC59_RS11470 4299db099ed0a535b1d4c9db782736a3 592 SUPERFAMILY SSF56425 241 359 5.53E-44 T 29-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CDC59_RS11470 4299db099ed0a535b1d4c9db782736a3 592 Gene3D G3DSA:3.50.50.60 5 297 1.2E-51 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS11470 4299db099ed0a535b1d4c9db782736a3 592 Gene3D G3DSA:3.50.50.60 308 434 1.5E-17 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS11470 4299db099ed0a535b1d4c9db782736a3 592 SUPERFAMILY SSF51905 9 264 1.14E-78 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS11470 4299db099ed0a535b1d4c9db782736a3 592 SUPERFAMILY SSF51905 363 429 1.14E-78 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS11470 4299db099ed0a535b1d4c9db782736a3 592 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 11 592 8.2E-282 T 29-03-2018 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CDC59_RS03500 66ff50664352b99b31be513c5fee40c7 166 SUPERFAMILY SSF142433 7 161 3.79E-57 T 29-03-2018 IPR008136 CinA, C-terminal CDC59_RS03500 66ff50664352b99b31be513c5fee40c7 166 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 14 157 1.0E-46 T 29-03-2018 IPR008136 CinA, C-terminal CDC59_RS03500 66ff50664352b99b31be513c5fee40c7 166 Gene3D G3DSA:3.90.950.20 2 166 2.3E-60 T 29-03-2018 CDC59_RS03500 66ff50664352b99b31be513c5fee40c7 166 Pfam PF02464 Competence-damaged protein 9 160 2.4E-61 T 29-03-2018 IPR008136 CinA, C-terminal CDC59_RS07865 d2eb71134578b60370d25e9982b34d0c 268 SUPERFAMILY SSF56300 20 250 1.19E-27 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CDC59_RS07865 d2eb71134578b60370d25e9982b34d0c 268 Hamap MF_00575 UDP-2,3-diacylglucosamine hydrolase [lpxH]. 1 268 99.063 T 29-03-2018 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 CDC59_RS07865 d2eb71134578b60370d25e9982b34d0c 268 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 21 231 6.7E-8 T 29-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 CDC59_RS07865 d2eb71134578b60370d25e9982b34d0c 268 Gene3D G3DSA:3.60.21.10 4 264 1.5E-23 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CDC59_RS07865 d2eb71134578b60370d25e9982b34d0c 268 TIGRFAM TIGR01854 lipid_A_lpxH: UDP-2,3-diacylglucosamine diphosphatase 21 245 4.0E-72 T 29-03-2018 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 CDC59_RS08455 52785d58a0604e53a422117cfd5e1d77 365 Pfam PF08402 TOBE domain 284 353 9.7E-7 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CDC59_RS08455 52785d58a0604e53a422117cfd5e1d77 365 SUPERFAMILY SSF50331 236 361 3.68E-26 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CDC59_RS08455 52785d58a0604e53a422117cfd5e1d77 365 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS08455 52785d58a0604e53a422117cfd5e1d77 365 Pfam PF00005 ABC transporter 20 161 9.3E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS08455 52785d58a0604e53a422117cfd5e1d77 365 Gene3D G3DSA:2.40.50.140 294 345 4.6E-14 T 29-03-2018 CDC59_RS08455 52785d58a0604e53a422117cfd5e1d77 365 SMART SM00382 28 219 1.9E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS08455 52785d58a0604e53a422117cfd5e1d77 365 Gene3D G3DSA:3.40.50.300 1 238 4.4E-70 T 29-03-2018 CDC59_RS08455 52785d58a0604e53a422117cfd5e1d77 365 SUPERFAMILY SSF52540 4 244 6.72E-87 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS08455 52785d58a0604e53a422117cfd5e1d77 365 Gene3D G3DSA:2.40.50.100 239 293 9.0E-4 T 29-03-2018 CDC59_RS09890 563c90f1b6ce8f9905b37f98a0623dd2 368 Gene3D G3DSA:3.40.50.970 2 350 6.5E-84 T 29-03-2018 CDC59_RS09890 563c90f1b6ce8f9905b37f98a0623dd2 368 SUPERFAMILY SSF52518 25 352 1.97E-99 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CDC59_RS09890 563c90f1b6ce8f9905b37f98a0623dd2 368 Pfam PF00676 Dehydrogenase E1 component 39 319 2.8E-76 T 29-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 CDC59_RS09890 563c90f1b6ce8f9905b37f98a0623dd2 368 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 11 349 1.1E-143 T 29-03-2018 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 CDC59_RS18970 c0039a367b6478464a5748bf26c89d26 184 Pfam PF01883 Iron-sulfur cluster assembly protein 22 84 1.9E-15 T 29-03-2018 IPR002744 MIP18 family-like CDC59_RS18970 c0039a367b6478464a5748bf26c89d26 184 TIGRFAM TIGR02159 PA_CoA_Oxy4: phenylacetate-CoA oxygenase, PaaJ subunit 30 183 2.7E-59 T 29-03-2018 IPR011883 Phenylacetate-CoA oxygenase, PaaJ subunit CDC59_RS18970 c0039a367b6478464a5748bf26c89d26 184 SUPERFAMILY SSF117916 22 113 1.44E-23 T 29-03-2018 IPR034904 Fe-S cluster assembly domain CDC59_RS18970 c0039a367b6478464a5748bf26c89d26 184 Gene3D G3DSA:3.30.300.130 19 115 8.9E-21 T 29-03-2018 IPR034904 Fe-S cluster assembly domain CDC59_RS13855 54ca7dea68312211c8f31a562e6aade5 433 PIRSF PIRSF000185 27 433 1.2E-163 T 29-03-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 CDC59_RS13855 54ca7dea68312211c8f31a562e6aade5 433 Gene3D G3DSA:3.40.50.10860 55 198 3.1E-54 T 29-03-2018 CDC59_RS13855 54ca7dea68312211c8f31a562e6aade5 433 SMART SM00839 201 430 1.0E-105 T 29-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CDC59_RS13855 54ca7dea68312211c8f31a562e6aade5 433 SUPERFAMILY SSF51735 199 432 5.26E-79 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS13855 54ca7dea68312211c8f31a562e6aade5 433 Gene3D G3DSA:3.40.50.720 199 433 5.0E-82 T 29-03-2018 CDC59_RS13855 54ca7dea68312211c8f31a562e6aade5 433 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 110 124 1.1E-32 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CDC59_RS13855 54ca7dea68312211c8f31a562e6aade5 433 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 190 212 1.1E-32 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CDC59_RS13855 54ca7dea68312211c8f31a562e6aade5 433 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 358 369 1.1E-32 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CDC59_RS13855 54ca7dea68312211c8f31a562e6aade5 433 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 232 252 1.1E-32 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CDC59_RS13855 54ca7dea68312211c8f31a562e6aade5 433 SUPERFAMILY SSF53223 18 201 9.6E-69 T 29-03-2018 CDC59_RS13855 54ca7dea68312211c8f31a562e6aade5 433 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 199 430 2.6E-79 T 29-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CDC59_RS13855 54ca7dea68312211c8f31a562e6aade5 433 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 53 181 3.6E-55 T 29-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CDC59_RS13855 54ca7dea68312211c8f31a562e6aade5 433 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 118 131 - T 29-03-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CDC59_RS04375 966d91e31e91ca0df4043c5637219b46 208 SUPERFAMILY SSF140478 38 195 4.18E-55 T 29-03-2018 IPR023353 LemA-like domain CDC59_RS04375 966d91e31e91ca0df4043c5637219b46 208 Gene3D G3DSA:1.20.1440.20 26 208 2.3E-54 T 29-03-2018 CDC59_RS04375 966d91e31e91ca0df4043c5637219b46 208 Pfam PF04011 LemA family 22 208 4.7E-67 T 29-03-2018 IPR007156 LemA CDC59_RS22535 c8f9d206a3586bc04ba9cfc7e8d22ab0 127 Gene3D G3DSA:3.10.180.10 3 127 6.5E-20 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CDC59_RS22535 c8f9d206a3586bc04ba9cfc7e8d22ab0 127 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 118 1.1E-4 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CDC59_RS22535 c8f9d206a3586bc04ba9cfc7e8d22ab0 127 SUPERFAMILY SSF54593 4 124 2.75E-21 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CDC59_RS08060 2491276df77331cecd5ebf4d3e9091d0 461 Pfam PF04966 Carbohydrate-selective porin, OprB family 78 461 1.7E-75 T 29-03-2018 IPR007049 Carbohydrate-selective porin OprB GO:0005215|GO:0006810|GO:0016021 CDC59_RS08105 fab2f25ee32468e180a56ae5e5a27571 251 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 1 251 39.038 T 29-03-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 CDC59_RS08105 fab2f25ee32468e180a56ae5e5a27571 251 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 1 237 1.2E-65 T 29-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 CDC59_RS08105 fab2f25ee32468e180a56ae5e5a27571 251 Pfam PF01975 Survival protein SurE 3 187 2.9E-58 T 29-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 CDC59_RS08105 fab2f25ee32468e180a56ae5e5a27571 251 Gene3D G3DSA:3.40.1210.10 1 251 5.1E-83 T 29-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 CDC59_RS08105 fab2f25ee32468e180a56ae5e5a27571 251 SUPERFAMILY SSF64167 1 249 1.12E-83 T 29-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 CDC59_RS06670 5da0485d453ff6cc134219037cee3491 249 Gene3D G3DSA:3.40.50.620 1 248 2.9E-88 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDC59_RS06670 5da0485d453ff6cc134219037cee3491 249 Pfam PF01012 Electron transfer flavoprotein domain 29 206 2.3E-45 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CDC59_RS06670 5da0485d453ff6cc134219037cee3491 249 SMART SM00893 23 211 1.1E-68 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CDC59_RS06670 5da0485d453ff6cc134219037cee3491 249 SUPERFAMILY SSF52402 1 242 1.26E-86 T 29-03-2018 CDC59_RS06670 5da0485d453ff6cc134219037cee3491 249 PIRSF PIRSF000090 1 249 3.1E-85 T 29-03-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 CDC59_RS06670 5da0485d453ff6cc134219037cee3491 249 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 155 175 - T 29-03-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 CDC59_RS11405 7d15257d82589d83107b6ffc400a5f69 265 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 14 262 34.028 T 29-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CDC59_RS11405 7d15257d82589d83107b6ffc400a5f69 265 SUPERFAMILY SSF51366 1 251 1.04E-90 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CDC59_RS11405 7d15257d82589d83107b6ffc400a5f69 265 Pfam PF00290 Tryptophan synthase alpha chain 8 257 1.3E-84 T 29-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CDC59_RS11405 7d15257d82589d83107b6ffc400a5f69 265 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 48 61 - T 29-03-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CDC59_RS11405 7d15257d82589d83107b6ffc400a5f69 265 Gene3D G3DSA:3.20.20.70 2 265 4.0E-81 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS11405 7d15257d82589d83107b6ffc400a5f69 265 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 8 259 2.3E-74 T 29-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CDC59_RS12550 842d95cc1586581c8ffc69865e1c80a1 403 Gene3D G3DSA:3.40.50.2300 316 381 5.1E-11 T 29-03-2018 CDC59_RS12550 842d95cc1586581c8ffc69865e1c80a1 403 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 284 302 1.1E-5 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CDC59_RS12550 842d95cc1586581c8ffc69865e1c80a1 403 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 360 375 1.1E-5 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CDC59_RS12550 842d95cc1586581c8ffc69865e1c80a1 403 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 75 91 1.1E-5 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CDC59_RS12550 842d95cc1586581c8ffc69865e1c80a1 403 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 53 69 1.1E-5 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CDC59_RS12550 842d95cc1586581c8ffc69865e1c80a1 403 SUPERFAMILY SSF53822 53 398 2.9E-98 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CDC59_RS12550 842d95cc1586581c8ffc69865e1c80a1 403 Gene3D G3DSA:3.40.50.2300 51 183 2.7E-21 T 29-03-2018 CDC59_RS12550 842d95cc1586581c8ffc69865e1c80a1 403 Pfam PF13458 Periplasmic binding protein 53 392 9.9E-63 T 29-03-2018 IPR028081 Leucine-binding protein domain CDC59_RS12550 842d95cc1586581c8ffc69865e1c80a1 403 Gene3D G3DSA:3.40.50.2300 184 315 4.5E-37 T 29-03-2018 CDC59_RS11620 275b03b0292efc61f89fce08dc55725c 219 Pfam PF04140 Isoprenylcysteine carboxyl methyltransferase (ICMT) family 112 196 7.0E-13 T 29-03-2018 IPR007269 Isoprenylcysteine carboxyl methyltransferase GO:0004671|GO:0006481|GO:0016021 Reactome: R-HSA-163841 CDC59_RS21265 33a8bf9d11bf2ee66cd521af13d55d86 709 Gene3D G3DSA:2.40.170.20 177 708 9.3E-79 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CDC59_RS21265 33a8bf9d11bf2ee66cd521af13d55d86 709 Pfam PF07715 TonB-dependent Receptor Plug Domain 68 164 1.4E-22 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CDC59_RS21265 33a8bf9d11bf2ee66cd521af13d55d86 709 Gene3D G3DSA:2.170.130.10 33 171 3.0E-29 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CDC59_RS21265 33a8bf9d11bf2ee66cd521af13d55d86 709 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 70 708 3.4E-107 T 29-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 CDC59_RS21265 33a8bf9d11bf2ee66cd521af13d55d86 709 SUPERFAMILY SSF56935 36 708 8.7E-130 T 29-03-2018 CDC59_RS21265 33a8bf9d11bf2ee66cd521af13d55d86 709 Pfam PF00593 TonB dependent receptor 236 708 3.1E-60 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CDC59_RS18490 6f27b11c76e403a8b7abb98a403e4e36 199 Pfam PF11159 Protein of unknown function (DUF2939) 14 106 1.5E-25 T 29-03-2018 IPR021330 Protein of unknown function DUF2939 CDC59_RS02370 b5fcc7b48ffb423a5c52b65c2fca4c2c 132 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS02370 b5fcc7b48ffb423a5c52b65c2fca4c2c 132 Gene3D G3DSA:3.90.1030.10 1 117 3.0E-51 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS02370 b5fcc7b48ffb423a5c52b65c2fca4c2c 132 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 27.299 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS02370 b5fcc7b48ffb423a5c52b65c2fca4c2c 132 TIGRFAM TIGR00059 L17: ribosomal protein bL17 7 117 2.3E-47 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS02370 b5fcc7b48ffb423a5c52b65c2fca4c2c 132 SUPERFAMILY SSF64263 1 119 6.54E-52 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS02370 b5fcc7b48ffb423a5c52b65c2fca4c2c 132 Pfam PF01196 Ribosomal protein L17 20 115 1.1E-36 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS15555 fbc19f45d096abf2add53148c54c5939 299 SUPERFAMILY SSF53850 9 271 7.34E-58 T 29-03-2018 CDC59_RS15555 fbc19f45d096abf2add53148c54c5939 299 Gene3D G3DSA:3.40.190.10 166 299 2.6E-17 T 29-03-2018 CDC59_RS15555 fbc19f45d096abf2add53148c54c5939 299 SMART SM00062 39 270 5.6E-53 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CDC59_RS15555 fbc19f45d096abf2add53148c54c5939 299 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 40 268 1.1E-47 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CDC59_RS15555 fbc19f45d096abf2add53148c54c5939 299 Gene3D G3DSA:3.40.190.10 7 165 3.1E-27 T 29-03-2018 CDC59_RS23845 c19b11b3945188177779f51fc08697f8 401 Gene3D G3DSA:3.40.50.880 356 400 0.092 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CDC59_RS23845 c19b11b3945188177779f51fc08697f8 401 Gene3D G3DSA:3.40.50.880 72 271 1.2E-40 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CDC59_RS23845 c19b11b3945188177779f51fc08697f8 401 Pfam PF01965 DJ-1/PfpI family 85 242 1.7E-21 T 29-03-2018 IPR002818 DJ-1/PfpI CDC59_RS23845 c19b11b3945188177779f51fc08697f8 401 SUPERFAMILY SSF52317 86 256 3.32E-40 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CDC59_RS09470 46451ee8b27fbb5bbaf59ce65222bd95 343 Gene3D G3DSA:3.40.50.20 163 256 8.4E-7 T 29-03-2018 CDC59_RS09470 46451ee8b27fbb5bbaf59ce65222bd95 343 Pfam PF02625 XdhC and CoxI family 15 83 7.8E-25 T 29-03-2018 IPR003777 XdhC- CoxI CDC59_RS09470 46451ee8b27fbb5bbaf59ce65222bd95 343 SUPERFAMILY SSF51735 164 270 1.8E-5 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS09470 46451ee8b27fbb5bbaf59ce65222bd95 343 Pfam PF13478 XdhC Rossmann domain 165 306 5.3E-39 T 29-03-2018 IPR027051 XdhC Rossmann domain CDC59_RS09010 7d191e3d2a6ab0ee9987aae4a46f6c7f 320 Gene3D G3DSA:3.60.20.30 188 320 2.6E-45 T 29-03-2018 CDC59_RS09010 7d191e3d2a6ab0ee9987aae4a46f6c7f 320 Pfam PF01112 Asparaginase 4 319 2.4E-118 T 29-03-2018 IPR000246 Peptidase T2, asparaginase 2 GO:0016787 CDC59_RS09010 7d191e3d2a6ab0ee9987aae4a46f6c7f 320 SUPERFAMILY SSF56235 185 317 1.36E-96 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CDC59_RS09010 7d191e3d2a6ab0ee9987aae4a46f6c7f 320 SUPERFAMILY SSF56235 3 155 1.36E-96 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CDC59_RS02210 ca4a6b7baa13e50eae118d79f91c74c1 125 PRINTS PR01034 Ribosomal protein S12 signature 58 77 5.4E-61 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS02210 ca4a6b7baa13e50eae118d79f91c74c1 125 PRINTS PR01034 Ribosomal protein S12 signature 110 122 5.4E-61 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS02210 ca4a6b7baa13e50eae118d79f91c74c1 125 PRINTS PR01034 Ribosomal protein S12 signature 27 42 5.4E-61 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS02210 ca4a6b7baa13e50eae118d79f91c74c1 125 PRINTS PR01034 Ribosomal protein S12 signature 77 94 5.4E-61 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS02210 ca4a6b7baa13e50eae118d79f91c74c1 125 PRINTS PR01034 Ribosomal protein S12 signature 42 57 5.4E-61 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS02210 ca4a6b7baa13e50eae118d79f91c74c1 125 PRINTS PR01034 Ribosomal protein S12 signature 94 110 5.4E-61 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS02210 ca4a6b7baa13e50eae118d79f91c74c1 125 PIRSF PIRSF002133 1 124 2.1E-55 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS02210 ca4a6b7baa13e50eae118d79f91c74c1 125 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 124 4.1E-71 T 29-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS02210 ca4a6b7baa13e50eae118d79f91c74c1 125 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 39.666 T 29-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS02210 ca4a6b7baa13e50eae118d79f91c74c1 125 Pfam PF00164 Ribosomal protein S12/S23 15 123 1.6E-43 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS02210 ca4a6b7baa13e50eae118d79f91c74c1 125 SUPERFAMILY SSF50249 2 123 1.11E-52 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDC59_RS02210 ca4a6b7baa13e50eae118d79f91c74c1 125 Gene3D G3DSA:2.40.50.140 1 125 4.7E-66 T 29-03-2018 CDC59_RS02210 ca4a6b7baa13e50eae118d79f91c74c1 125 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS17695 6cbc061a395723f33a910757adbb9aae 317 SUPERFAMILY SSF54292 206 316 1.57E-27 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CDC59_RS17695 6cbc061a395723f33a910757adbb9aae 317 Gene3D G3DSA:3.40.50.80 98 215 2.2E-22 T 29-03-2018 CDC59_RS17695 6cbc061a395723f33a910757adbb9aae 317 Gene3D G3DSA:3.10.20.30 216 316 1.5E-22 T 29-03-2018 IPR012675 Beta-grasp domain CDC59_RS17695 6cbc061a395723f33a910757adbb9aae 317 SUPERFAMILY SSF52343 99 219 6.68E-29 T 29-03-2018 CDC59_RS17695 6cbc061a395723f33a910757adbb9aae 317 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 240 309 1.9E-12 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CDC59_RS17695 6cbc061a395723f33a910757adbb9aae 317 Gene3D G3DSA:2.40.30.10 1 97 7.1E-16 T 29-03-2018 CDC59_RS17695 6cbc061a395723f33a910757adbb9aae 317 Pfam PF00175 Oxidoreductase NAD-binding domain 106 197 6.7E-7 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CDC59_RS17695 6cbc061a395723f33a910757adbb9aae 317 SUPERFAMILY SSF63380 2 93 1.61E-22 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CDC59_RS17695 6cbc061a395723f33a910757adbb9aae 317 PRINTS PR00409 Phthalate dioxygenase reductase family signature 105 124 4.0E-37 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CDC59_RS17695 6cbc061a395723f33a910757adbb9aae 317 PRINTS PR00409 Phthalate dioxygenase reductase family signature 46 60 4.0E-37 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CDC59_RS17695 6cbc061a395723f33a910757adbb9aae 317 PRINTS PR00409 Phthalate dioxygenase reductase family signature 130 139 4.0E-37 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CDC59_RS17695 6cbc061a395723f33a910757adbb9aae 317 PRINTS PR00409 Phthalate dioxygenase reductase family signature 25 35 4.0E-37 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CDC59_RS17695 6cbc061a395723f33a910757adbb9aae 317 PRINTS PR00409 Phthalate dioxygenase reductase family signature 83 97 4.0E-37 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CDC59_RS17695 6cbc061a395723f33a910757adbb9aae 317 PRINTS PR00409 Phthalate dioxygenase reductase family signature 184 192 4.0E-37 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CDC59_RS17695 6cbc061a395723f33a910757adbb9aae 317 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 268 276 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CDC59_RS17695 6cbc061a395723f33a910757adbb9aae 317 Pfam PF00970 Oxidoreductase FAD-binding domain 4 95 2.4E-5 T 29-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CDC59_RS13390 67725bd9e1449a1401d8faeec5be2aa6 374 SUPERFAMILY SSF53474 49 309 1.58E-33 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS13390 67725bd9e1449a1401d8faeec5be2aa6 374 Gene3D G3DSA:3.40.50.1820 38 370 4.7E-23 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS13390 67725bd9e1449a1401d8faeec5be2aa6 374 Pfam PF00561 alpha/beta hydrolase fold 82 324 4.8E-11 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS13390 67725bd9e1449a1401d8faeec5be2aa6 374 PIRSF PIRSF005211 3 373 3.0E-112 T 29-03-2018 IPR012020 AB hydrolase 4 family CDC59_RS11220 7236cee50c93c29411d7519a93528e1c 240 Gene3D G3DSA:1.10.10.10 126 231 8.0E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS11220 7236cee50c93c29411d7519a93528e1c 240 SMART SM00862 148 224 2.8E-16 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDC59_RS11220 7236cee50c93c29411d7519a93528e1c 240 SUPERFAMILY SSF46894 126 225 1.05E-21 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CDC59_RS11220 7236cee50c93c29411d7519a93528e1c 240 Gene3D G3DSA:3.40.50.2300 1 125 1.2E-11 T 29-03-2018 CDC59_RS11220 7236cee50c93c29411d7519a93528e1c 240 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 224 2.4E-15 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDC59_RS11220 7236cee50c93c29411d7519a93528e1c 240 SUPERFAMILY SSF52172 2 130 9.68E-14 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS20185 a5d4b5953d9c52fa4d341aece14abd28 355 Gene3D G3DSA:2.30.330.10 272 351 3.3E-14 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) CDC59_RS20185 a5d4b5953d9c52fa4d341aece14abd28 355 TIGRFAM TIGR02551 SpaO_YscQ: type III secretion apparatus protein, YscQ/HrcQ family 49 347 6.4E-56 T 29-03-2018 IPR013385 Type III secretion system apparatus protein YscQ/HrcQ/SpaO GO:0030254 CDC59_RS20185 a5d4b5953d9c52fa4d341aece14abd28 355 SUPERFAMILY SSF101801 279 347 4.84E-12 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) CDC59_RS20185 a5d4b5953d9c52fa4d341aece14abd28 355 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 279 348 2.0E-11 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) CDC59_RS13435 8c53743554f19e3693e7b088e1fe9c8f 388 Gene3D G3DSA:3.30.470.20 96 239 1.7E-55 T 29-03-2018 CDC59_RS13435 8c53743554f19e3693e7b088e1fe9c8f 388 Gene3D G3DSA:3.30.1490.20 21 95 1.0E-27 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CDC59_RS13435 8c53743554f19e3693e7b088e1fe9c8f 388 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 385 2.5E-160 T 29-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CDC59_RS13435 8c53743554f19e3693e7b088e1fe9c8f 388 Gene3D G3DSA:3.40.50.261 240 385 2.9E-44 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CDC59_RS13435 8c53743554f19e3693e7b088e1fe9c8f 388 SUPERFAMILY SSF56059 1 238 6.01E-86 T 29-03-2018 CDC59_RS13435 8c53743554f19e3693e7b088e1fe9c8f 388 Pfam PF00549 CoA-ligase 262 382 3.7E-25 T 29-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CDC59_RS13435 8c53743554f19e3693e7b088e1fe9c8f 388 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 257 282 - T 29-03-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CDC59_RS13435 8c53743554f19e3693e7b088e1fe9c8f 388 PIRSF PIRSF001554 1 388 1.6E-153 T 29-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CDC59_RS13435 8c53743554f19e3693e7b088e1fe9c8f 388 SUPERFAMILY SSF52210 241 384 2.22E-53 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CDC59_RS13435 8c53743554f19e3693e7b088e1fe9c8f 388 Pfam PF08442 ATP-grasp domain 2 202 4.9E-81 T 29-03-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CDC59_RS13435 8c53743554f19e3693e7b088e1fe9c8f 388 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 43.93 T 29-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CDC59_RS15310 7ea900ac38b6f5a5dfb5b7b22a1e5aaf 246 Pfam PF00106 short chain dehydrogenase 2 190 5.4E-34 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS15310 7ea900ac38b6f5a5dfb5b7b22a1e5aaf 246 Gene3D G3DSA:3.40.50.720 1 245 1.2E-41 T 29-03-2018 CDC59_RS15310 7ea900ac38b6f5a5dfb5b7b22a1e5aaf 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 3.6E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS15310 7ea900ac38b6f5a5dfb5b7b22a1e5aaf 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 3.6E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS15310 7ea900ac38b6f5a5dfb5b7b22a1e5aaf 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 3.6E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS15310 7ea900ac38b6f5a5dfb5b7b22a1e5aaf 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 3.6E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS15310 7ea900ac38b6f5a5dfb5b7b22a1e5aaf 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 3.6E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS15310 7ea900ac38b6f5a5dfb5b7b22a1e5aaf 246 SUPERFAMILY SSF51735 2 243 2.92E-48 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS03360 4f43ab7cd6977217f9d0cb044e5ffa35 515 Gene3D G3DSA:1.10.287.950 318 515 7.8E-46 T 29-03-2018 CDC59_RS03360 4f43ab7cd6977217f9d0cb044e5ffa35 515 SMART SM00283 266 513 1.6E-88 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CDC59_RS03360 4f43ab7cd6977217f9d0cb044e5ffa35 515 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 325 481 6.7E-51 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CDC59_RS03360 4f43ab7cd6977217f9d0cb044e5ffa35 515 SMART SM01049 33 127 1.9E-32 T 29-03-2018 IPR033480 Single Cache domain 2 CDC59_RS03360 4f43ab7cd6977217f9d0cb044e5ffa35 515 Gene3D G3DSA:1.10.287.950 221 317 3.6E-11 T 29-03-2018 CDC59_RS03360 4f43ab7cd6977217f9d0cb044e5ffa35 515 Gene3D G3DSA:3.30.450.20 27 192 2.6E-42 T 29-03-2018 CDC59_RS03360 4f43ab7cd6977217f9d0cb044e5ffa35 515 Pfam PF17200 Single Cache domain 2 37 183 3.9E-34 T 29-03-2018 IPR033480 Single Cache domain 2 CDC59_RS03360 4f43ab7cd6977217f9d0cb044e5ffa35 515 SUPERFAMILY SSF58104 241 513 1.11E-68 T 29-03-2018 CDC59_RS09580 0c686328182b6c35dd3534d214f24088 341 Gene3D G3DSA:3.40.50.80 203 333 2.5E-27 T 29-03-2018 CDC59_RS09580 0c686328182b6c35dd3534d214f24088 341 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 40 48 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CDC59_RS09580 0c686328182b6c35dd3534d214f24088 341 Gene3D G3DSA:3.10.20.30 1 110 3.6E-25 T 29-03-2018 IPR012675 Beta-grasp domain CDC59_RS09580 0c686328182b6c35dd3534d214f24088 341 SUPERFAMILY SSF54292 1 95 4.45E-28 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CDC59_RS09580 0c686328182b6c35dd3534d214f24088 341 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 212 231 4.9E-5 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CDC59_RS09580 0c686328182b6c35dd3534d214f24088 341 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 301 309 4.9E-5 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CDC59_RS09580 0c686328182b6c35dd3534d214f24088 341 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 154 161 4.9E-5 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CDC59_RS09580 0c686328182b6c35dd3534d214f24088 341 Pfam PF00970 Oxidoreductase FAD-binding domain 111 203 6.6E-18 T 29-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CDC59_RS09580 0c686328182b6c35dd3534d214f24088 341 Pfam PF00175 Oxidoreductase NAD-binding domain 213 315 6.1E-19 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CDC59_RS09580 0c686328182b6c35dd3534d214f24088 341 SUPERFAMILY SSF63380 77 205 1.97E-25 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CDC59_RS09580 0c686328182b6c35dd3534d214f24088 341 Gene3D G3DSA:2.40.30.10 111 202 1.0E-20 T 29-03-2018 CDC59_RS09580 0c686328182b6c35dd3534d214f24088 341 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 10 87 4.3E-16 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CDC59_RS09580 0c686328182b6c35dd3534d214f24088 341 SUPERFAMILY SSF52343 203 336 5.76E-32 T 29-03-2018 CDC59_RS09580 0c686328182b6c35dd3534d214f24088 341 PRINTS PR00410 Phenol hydroxylase reductase family signature 212 231 2.5E-25 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CDC59_RS09580 0c686328182b6c35dd3534d214f24088 341 PRINTS PR00410 Phenol hydroxylase reductase family signature 154 161 2.5E-25 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CDC59_RS09580 0c686328182b6c35dd3534d214f24088 341 PRINTS PR00410 Phenol hydroxylase reductase family signature 237 246 2.5E-25 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CDC59_RS09580 0c686328182b6c35dd3534d214f24088 341 PRINTS PR00410 Phenol hydroxylase reductase family signature 197 206 2.5E-25 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CDC59_RS09580 0c686328182b6c35dd3534d214f24088 341 PRINTS PR00410 Phenol hydroxylase reductase family signature 137 149 2.5E-25 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CDC59_RS09580 0c686328182b6c35dd3534d214f24088 341 PRINTS PR00410 Phenol hydroxylase reductase family signature 301 309 2.5E-25 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CDC59_RS18910 b689a9ca68724e03527b75c4958adda0 160 SUPERFAMILY SSF54523 12 143 2.2E-13 T 29-03-2018 CDC59_RS18910 b689a9ca68724e03527b75c4958adda0 160 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 9 31 9.3E-4 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS18910 b689a9ca68724e03527b75c4958adda0 160 Gene3D G3DSA:3.30.700.10 12 149 1.7E-7 T 29-03-2018 CDC59_RS18910 b689a9ca68724e03527b75c4958adda0 160 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 9 29 - T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS14505 a15092a8ad76a7e04f3167326303b7b0 140 Gene3D G3DSA:3.40.250.10 37 140 2.9E-30 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS14505 a15092a8ad76a7e04f3167326303b7b0 140 SUPERFAMILY SSF52821 26 140 6.42E-35 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS14505 a15092a8ad76a7e04f3167326303b7b0 140 Pfam PF00581 Rhodanese-like domain 42 133 7.3E-19 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS14505 a15092a8ad76a7e04f3167326303b7b0 140 SMART SM00450 40 137 6.8E-27 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS13945 159874acf489d6939f3fc05c1735172b 209 Pfam PF05724 Thiopurine S-methyltransferase (TPMT) 14 206 4.7E-47 T 29-03-2018 IPR008854 TPMT family GO:0008757 KEGG: 00983+2.1.1.67|Reactome: R-HSA-156581 CDC59_RS13945 159874acf489d6939f3fc05c1735172b 209 SUPERFAMILY SSF53335 13 206 2.24E-38 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS13945 159874acf489d6939f3fc05c1735172b 209 Gene3D G3DSA:3.40.50.150 28 191 8.5E-19 T 29-03-2018 CDC59_RS06660 5171184cdab8293c8a49053d18f55de7 217 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 32 215 1.0E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS06660 5171184cdab8293c8a49053d18f55de7 217 SUPERFAMILY SSF161098 7 211 3.92E-47 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS06660 5171184cdab8293c8a49053d18f55de7 217 Gene3D G3DSA:1.10.3720.10 1 217 5.0E-38 T 29-03-2018 CDC59_RS07820 a4c49a95a26a8dab4a0dd3e19b98ce95 271 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 118 135 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CDC59_RS07820 a4c49a95a26a8dab4a0dd3e19b98ce95 271 SUPERFAMILY SSF51430 5 263 1.7E-83 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CDC59_RS07820 a4c49a95a26a8dab4a0dd3e19b98ce95 271 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 33 50 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CDC59_RS07820 a4c49a95a26a8dab4a0dd3e19b98ce95 271 Gene3D G3DSA:3.20.20.100 1 267 2.6E-85 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CDC59_RS07820 a4c49a95a26a8dab4a0dd3e19b98ce95 271 PIRSF PIRSF000097 1 269 2.0E-65 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CDC59_RS07820 a4c49a95a26a8dab4a0dd3e19b98ce95 271 PRINTS PR00069 Aldo-keto reductase signature 190 214 1.1E-45 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CDC59_RS07820 a4c49a95a26a8dab4a0dd3e19b98ce95 271 PRINTS PR00069 Aldo-keto reductase signature 29 53 1.1E-45 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CDC59_RS07820 a4c49a95a26a8dab4a0dd3e19b98ce95 271 PRINTS PR00069 Aldo-keto reductase signature 85 103 1.1E-45 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CDC59_RS07820 a4c49a95a26a8dab4a0dd3e19b98ce95 271 PRINTS PR00069 Aldo-keto reductase signature 153 182 1.1E-45 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CDC59_RS07820 a4c49a95a26a8dab4a0dd3e19b98ce95 271 PRINTS PR00069 Aldo-keto reductase signature 118 135 1.1E-45 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CDC59_RS07820 a4c49a95a26a8dab4a0dd3e19b98ce95 271 Pfam PF00248 Aldo/keto reductase family 11 254 1.3E-50 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CDC59_RS08850 e95e931bdcaded6a50eddc0854834404 307 Pfam PF00563 EAL domain 43 256 5.8E-15 T 29-03-2018 IPR001633 EAL domain CDC59_RS08850 e95e931bdcaded6a50eddc0854834404 307 Gene3D G3DSA:3.20.20.450 34 262 2.4E-20 T 29-03-2018 IPR001633 EAL domain CDC59_RS08850 e95e931bdcaded6a50eddc0854834404 307 SUPERFAMILY SSF141868 61 257 3.27E-18 T 29-03-2018 IPR001633 EAL domain CDC59_RS01075 006de0eb104e03b25c4c80c94798aa84 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 1.2E-15 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS01075 006de0eb104e03b25c4c80c94798aa84 303 Gene3D G3DSA:3.40.190.10 175 264 1.6E-24 T 29-03-2018 CDC59_RS01075 006de0eb104e03b25c4c80c94798aa84 303 SUPERFAMILY SSF53850 91 297 4.34E-43 T 29-03-2018 CDC59_RS01075 006de0eb104e03b25c4c80c94798aa84 303 Gene3D G3DSA:1.10.10.10 3 84 2.4E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS01075 006de0eb104e03b25c4c80c94798aa84 303 Pfam PF03466 LysR substrate binding domain 90 291 7.9E-38 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS01075 006de0eb104e03b25c4c80c94798aa84 303 Gene3D G3DSA:3.40.190.10 86 174 5.5E-17 T 29-03-2018 CDC59_RS01075 006de0eb104e03b25c4c80c94798aa84 303 SUPERFAMILY SSF46785 4 85 2.07E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS19380 e934d49772cf7c054d3cba066744207b 226 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 7 221 1.4E-52 T 29-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein CDC59_RS19380 e934d49772cf7c054d3cba066744207b 226 Pfam PF01168 Alanine racemase, N-terminal domain 25 221 6.5E-23 T 29-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CDC59_RS19380 e934d49772cf7c054d3cba066744207b 226 PIRSF PIRSF004848 1 226 2.0E-63 T 29-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein CDC59_RS19380 e934d49772cf7c054d3cba066744207b 226 Gene3D G3DSA:3.20.20.10 2 226 4.8E-57 T 29-03-2018 IPR029066 PLP-binding barrel CDC59_RS19380 e934d49772cf7c054d3cba066744207b 226 SUPERFAMILY SSF51419 4 219 1.37E-69 T 29-03-2018 IPR029066 PLP-binding barrel CDC59_RS23440 58c65929b2b3f58faabff45598cd7e85 395 Gene3D G3DSA:3.40.50.720 162 393 2.3E-15 T 29-03-2018 CDC59_RS23440 58c65929b2b3f58faabff45598cd7e85 395 Pfam PF00899 ThiF family 173 311 1.4E-8 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CDC59_RS23440 58c65929b2b3f58faabff45598cd7e85 395 SUPERFAMILY SSF69572 175 301 5.89E-14 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CDC59_RS16080 4c4a9536247c73db09819f2583022fe3 547 Pfam PF01566 Natural resistance-associated macrophage protein 71 425 1.8E-86 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CDC59_RS00420 b17421e9de96bccf0e54bf5d6164b264 446 Pfam PF00512 His Kinase A (phospho-acceptor) domain 227 290 2.7E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS00420 b17421e9de96bccf0e54bf5d6164b264 446 SUPERFAMILY SSF47384 210 291 3.73E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS00420 b17421e9de96bccf0e54bf5d6164b264 446 PRINTS PR00344 Bacterial sensor protein C-terminal signature 390 400 7.5E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS00420 b17421e9de96bccf0e54bf5d6164b264 446 PRINTS PR00344 Bacterial sensor protein C-terminal signature 404 422 7.5E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS00420 b17421e9de96bccf0e54bf5d6164b264 446 PRINTS PR00344 Bacterial sensor protein C-terminal signature 372 386 7.5E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS00420 b17421e9de96bccf0e54bf5d6164b264 446 PRINTS PR00344 Bacterial sensor protein C-terminal signature 430 443 7.5E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS00420 b17421e9de96bccf0e54bf5d6164b264 446 Gene3D G3DSA:1.20.5.1040 121 173 2.7E-10 T 29-03-2018 CDC59_RS00420 b17421e9de96bccf0e54bf5d6164b264 446 Gene3D G3DSA:1.20.5.1040 10 64 1.9E-11 T 29-03-2018 CDC59_RS00420 b17421e9de96bccf0e54bf5d6164b264 446 SMART SM00387 335 446 1.0E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS00420 b17421e9de96bccf0e54bf5d6164b264 446 SMART SM00388 226 291 8.0E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS00420 b17421e9de96bccf0e54bf5d6164b264 446 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 337 444 6.8E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS00420 b17421e9de96bccf0e54bf5d6164b264 446 SUPERFAMILY SSF55874 281 444 3.8E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS00420 b17421e9de96bccf0e54bf5d6164b264 446 Gene3D G3DSA:1.10.287.130 216 287 4.1E-13 T 29-03-2018 CDC59_RS00420 b17421e9de96bccf0e54bf5d6164b264 446 Gene3D G3DSA:3.30.565.10 296 446 3.2E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS07780 d392ae67471fda98f18d6240e374953d 261 SMART SM00849 13 172 6.1E-10 T 29-03-2018 IPR001279 Metallo-beta-lactamase CDC59_RS07780 d392ae67471fda98f18d6240e374953d 261 Gene3D G3DSA:3.60.15.10 10 255 1.7E-36 T 29-03-2018 IPR001279 Metallo-beta-lactamase CDC59_RS07780 d392ae67471fda98f18d6240e374953d 261 SUPERFAMILY SSF56281 1 232 1.44E-39 T 29-03-2018 IPR001279 Metallo-beta-lactamase CDC59_RS07780 d392ae67471fda98f18d6240e374953d 261 Pfam PF12706 Beta-lactamase superfamily domain 28 210 8.2E-17 T 29-03-2018 IPR001279 Metallo-beta-lactamase CDC59_RS17025 dc6360b227c655f02fa0da601b463e02 245 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 29-03-2018 IPR019776 Flagellar basal body rod protein, conserved site CDC59_RS17025 dc6360b227c655f02fa0da601b463e02 245 Pfam PF00460 Flagella basal body rod protein 5 35 2.2E-6 T 29-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CDC59_RS17025 dc6360b227c655f02fa0da601b463e02 245 SUPERFAMILY SSF117143 77 203 3.4E-22 T 29-03-2018 CDC59_RS17025 dc6360b227c655f02fa0da601b463e02 245 TIGRFAM TIGR02490 flgF: flagellar basal-body rod protein FlgF 5 221 9.7E-57 T 29-03-2018 IPR012836 Flagellar basal-body rod FlgF GO:0030694|GO:0071973 CDC59_RS17025 dc6360b227c655f02fa0da601b463e02 245 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 121 7.9E-40 T 29-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G CDC59_RS17025 dc6360b227c655f02fa0da601b463e02 245 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 170 241 1.3E-18 T 29-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CDC59_RS03185 fff7c17dfecedb030e455ca7f9e6442a 409 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 16 409 4.7E-125 T 29-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CDC59_RS03185 fff7c17dfecedb030e455ca7f9e6442a 409 Pfam PF01960 ArgJ family 24 409 4.1E-147 T 29-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CDC59_RS03185 fff7c17dfecedb030e455ca7f9e6442a 409 SUPERFAMILY SSF56266 16 406 9.68E-142 T 29-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CDC59_RS03185 fff7c17dfecedb030e455ca7f9e6442a 409 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 24 407 0.0 T 29-03-2018 CDC59_RS03185 fff7c17dfecedb030e455ca7f9e6442a 409 Gene3D G3DSA:3.60.70.12 9 280 1.5E-105 T 29-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CDC59_RS03185 fff7c17dfecedb030e455ca7f9e6442a 409 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 409 161.724 T 29-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CDC59_RS21150 f4560800cb2caf9877923cd58bd7ae71 477 Pfam PF02321 Outer membrane efflux protein 288 470 3.1E-20 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CDC59_RS21150 f4560800cb2caf9877923cd58bd7ae71 477 Pfam PF02321 Outer membrane efflux protein 84 264 1.5E-20 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CDC59_RS21150 f4560800cb2caf9877923cd58bd7ae71 477 SUPERFAMILY SSF56954 74 471 3.66E-67 T 29-03-2018 CDC59_RS21150 f4560800cb2caf9877923cd58bd7ae71 477 SUPERFAMILY SSF56954 25 47 3.66E-67 T 29-03-2018 CDC59_RS21150 f4560800cb2caf9877923cd58bd7ae71 477 Gene3D G3DSA:1.20.1600.10 22 472 3.9E-56 T 29-03-2018 CDC59_RS17615 aa64ee23cc4459401c96a40213ab38fe 164 SUPERFAMILY SSF54637 7 154 2.23E-45 T 29-03-2018 IPR029069 HotDog domain CDC59_RS17615 aa64ee23cc4459401c96a40213ab38fe 164 Pfam PF03061 Thioesterase superfamily 23 95 8.3E-17 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CDC59_RS17615 aa64ee23cc4459401c96a40213ab38fe 164 Gene3D G3DSA:3.10.129.10 1 153 2.9E-49 T 29-03-2018 CDC59_RS07575 31bcf54157440f807331995c8df88038 187 SUPERFAMILY SSF53474 2 162 1.09E-10 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS07575 31bcf54157440f807331995c8df88038 187 Gene3D G3DSA:3.40.50.1820 1 113 1.8E-5 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS07575 31bcf54157440f807331995c8df88038 187 Gene3D G3DSA:3.40.50.1820 114 172 0.019 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS14745 209ea880eec5d114b0397d675ee16a82 292 Pfam PF03099 Biotin/lipoate A/B protein ligase family 70 174 1.8E-11 T 29-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CDC59_RS14745 209ea880eec5d114b0397d675ee16a82 292 SUPERFAMILY SSF50037 237 284 6.41E-7 T 29-03-2018 IPR008988 Transcriptional repressor, C-terminal CDC59_RS14745 209ea880eec5d114b0397d675ee16a82 292 Gene3D G3DSA:3.30.930.10 13 236 9.1E-50 T 29-03-2018 CDC59_RS14745 209ea880eec5d114b0397d675ee16a82 292 Pfam PF02237 Biotin protein ligase C terminal domain 238 284 6.2E-11 T 29-03-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 CDC59_RS14745 209ea880eec5d114b0397d675ee16a82 292 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 67 284 1.1E-39 T 29-03-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 CDC59_RS14745 209ea880eec5d114b0397d675ee16a82 292 SUPERFAMILY SSF55681 19 234 9.77E-40 T 29-03-2018 CDC59_RS14745 209ea880eec5d114b0397d675ee16a82 292 Gene3D G3DSA:2.30.30.100 238 285 1.1E-12 T 29-03-2018 CDC59_RS02815 ee971fdb78583e81e889f1f60607f9f9 309 Pfam PF05175 Methyltransferase small domain 126 219 1.5E-13 T 29-03-2018 IPR007848 Methyltransferase small domain GO:0008168 CDC59_RS02815 ee971fdb78583e81e889f1f60607f9f9 309 Gene3D G3DSA:3.40.50.150 102 304 1.8E-40 T 29-03-2018 CDC59_RS02815 ee971fdb78583e81e889f1f60607f9f9 309 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 207 213 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CDC59_RS02815 ee971fdb78583e81e889f1f60607f9f9 309 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 45 297 1.8E-83 T 29-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 CDC59_RS02815 ee971fdb78583e81e889f1f60607f9f9 309 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 28 300 4.8E-67 T 29-03-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 CDC59_RS02815 ee971fdb78583e81e889f1f60607f9f9 309 SUPERFAMILY SSF53335 31 299 5.53E-56 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS02815 ee971fdb78583e81e889f1f60607f9f9 309 Gene3D G3DSA:1.10.8.10 24 101 3.1E-16 T 29-03-2018 CDC59_RS02815 ee971fdb78583e81e889f1f60607f9f9 309 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 23 302 43.275 T 29-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 CDC59_RS17185 61e2d10cdda816a0a4bf1057532bde65 248 Pfam PF02108 Flagellar assembly protein FliH 94 219 2.3E-34 T 29-03-2018 IPR018035 Flagellar assembly protein FliH/Type III secretion system HrpE CDC59_RS17185 61e2d10cdda816a0a4bf1057532bde65 248 PRINTS PR01003 Flagellar assembly protein FliH signature 184 200 2.2E-15 T 29-03-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 CDC59_RS17185 61e2d10cdda816a0a4bf1057532bde65 248 PRINTS PR01003 Flagellar assembly protein FliH signature 201 226 2.2E-15 T 29-03-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 CDC59_RS17185 61e2d10cdda816a0a4bf1057532bde65 248 PRINTS PR01003 Flagellar assembly protein FliH signature 53 75 2.2E-15 T 29-03-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 CDC59_RS17185 61e2d10cdda816a0a4bf1057532bde65 248 PRINTS PR01003 Flagellar assembly protein FliH signature 115 132 2.2E-15 T 29-03-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 CDC59_RS17185 61e2d10cdda816a0a4bf1057532bde65 248 PRINTS PR01003 Flagellar assembly protein FliH signature 76 94 2.2E-15 T 29-03-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 CDC59_RS17185 61e2d10cdda816a0a4bf1057532bde65 248 PRINTS PR01003 Flagellar assembly protein FliH signature 156 183 2.2E-15 T 29-03-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 CDC59_RS07930 ef65138117754384521392d3862c9dba 374 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 25 64 2.4E-7 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CDC59_RS07930 ef65138117754384521392d3862c9dba 374 SUPERFAMILY SSF161098 155 342 1.44E-23 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS07930 ef65138117754384521392d3862c9dba 374 Gene3D G3DSA:1.10.3720.10 29 348 6.1E-48 T 29-03-2018 CDC59_RS07930 ef65138117754384521392d3862c9dba 374 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 178 359 9.9E-30 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS18815 aac1cef25c8c2b9e537aec15dddc9e31 203 SUPERFAMILY SSF51735 1 201 2.0E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS18815 aac1cef25c8c2b9e537aec15dddc9e31 203 Gene3D G3DSA:3.40.50.720 1 203 7.5E-28 T 29-03-2018 CDC59_RS18815 aac1cef25c8c2b9e537aec15dddc9e31 203 Pfam PF13460 NAD(P)H-binding 7 186 7.9E-35 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS03510 9a6d23a31f8c48975b17599ed69c58bf 332 PIRSF PIRSF005303 9 328 1.0E-78 T 29-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 CDC59_RS03510 9a6d23a31f8c48975b17599ed69c58bf 332 SUPERFAMILY SSF56042 152 312 3.44E-37 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CDC59_RS03510 9a6d23a31f8c48975b17599ed69c58bf 332 Gene3D G3DSA:3.90.650.10 153 329 2.9E-47 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CDC59_RS03510 9a6d23a31f8c48975b17599ed69c58bf 332 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 16 328 2.8E-97 T 29-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 CDC59_RS03510 9a6d23a31f8c48975b17599ed69c58bf 332 Gene3D G3DSA:3.30.1330.10 12 152 1.3E-35 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CDC59_RS03510 9a6d23a31f8c48975b17599ed69c58bf 332 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 14 325 29.235 T 29-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 CDC59_RS03510 9a6d23a31f8c48975b17599ed69c58bf 332 Pfam PF02769 AIR synthase related protein, C-terminal domain 158 311 1.0E-11 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CDC59_RS03510 9a6d23a31f8c48975b17599ed69c58bf 332 Pfam PF00586 AIR synthase related protein, N-terminal domain 37 145 7.3E-24 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CDC59_RS03510 9a6d23a31f8c48975b17599ed69c58bf 332 SUPERFAMILY SSF55326 13 146 6.11E-34 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CDC59_RS07670 4bcdfc3a806b5f0520a2795cb12332ce 273 Pfam PF12697 Alpha/beta hydrolase family 6 253 1.2E-12 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS07670 4bcdfc3a806b5f0520a2795cb12332ce 273 SUPERFAMILY SSF53474 5 259 4.42E-29 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS07670 4bcdfc3a806b5f0520a2795cb12332ce 273 Gene3D G3DSA:3.40.50.1820 2 270 6.8E-28 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS00530 51c2a1d1a49569b44b57553ae5ed9240 590 PIRSF PIRSF001294 1 590 9.3E-249 T 29-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CDC59_RS00530 51c2a1d1a49569b44b57553ae5ed9240 590 Pfam PF03814 Potassium-transporting ATPase A subunit 10 588 4.4E-251 T 29-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CDC59_RS00530 51c2a1d1a49569b44b57553ae5ed9240 590 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 239 589 1.4E-162 T 29-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CDC59_RS00530 51c2a1d1a49569b44b57553ae5ed9240 590 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 1 590 36.655 T 29-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CDC59_RS06435 dba0395674e2b0db26cc61c999ad2296 303 Gene3D G3DSA:3.60.40.10 3 242 3.7E-37 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CDC59_RS06435 dba0395674e2b0db26cc61c999ad2296 303 SUPERFAMILY SSF81606 1 243 2.09E-50 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CDC59_RS06435 dba0395674e2b0db26cc61c999ad2296 303 SMART SM00332 1 241 3.7E-11 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CDC59_RS06435 dba0395674e2b0db26cc61c999ad2296 303 SMART SM00331 7 243 1.1E-13 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CDC59_RS06435 dba0395674e2b0db26cc61c999ad2296 303 Pfam PF13672 Protein phosphatase 2C 9 204 5.0E-11 T 29-03-2018 CDC59_RS01315 5414132986c5e3d97ce7f8d8ee9b43d0 782 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 543 623 1.3E-20 T 29-03-2018 IPR022385 Rhs repeat-associated core GO:0097264 CDC59_RS01315 5414132986c5e3d97ce7f8d8ee9b43d0 782 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 105 144 3.4E-5 T 29-03-2018 IPR006530 YD repeat CDC59_RS01315 5414132986c5e3d97ce7f8d8ee9b43d0 782 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 176 206 1.1E-5 T 29-03-2018 IPR006530 YD repeat CDC59_RS01315 5414132986c5e3d97ce7f8d8ee9b43d0 782 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 35 63 6.5E-7 T 29-03-2018 IPR006530 YD repeat CDC59_RS01315 5414132986c5e3d97ce7f8d8ee9b43d0 782 Pfam PF05593 RHS Repeat 229 267 3.9E-6 T 29-03-2018 IPR031325 RHS repeat CDC59_RS01315 5414132986c5e3d97ce7f8d8ee9b43d0 782 Pfam PF05593 RHS Repeat 125 161 5.9E-11 T 29-03-2018 IPR031325 RHS repeat CDC59_RS01315 5414132986c5e3d97ce7f8d8ee9b43d0 782 Pfam PF05593 RHS Repeat 177 212 6.6E-6 T 29-03-2018 IPR031325 RHS repeat CDC59_RS01315 5414132986c5e3d97ce7f8d8ee9b43d0 782 Pfam PF05593 RHS Repeat 35 66 3.7E-11 T 29-03-2018 IPR031325 RHS repeat CDC59_RS13340 ec13484546ac6e88e876161e12da0313 354 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 139 150 - T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CDC59_RS13340 ec13484546ac6e88e876161e12da0313 354 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 73 85 - T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CDC59_RS13340 ec13484546ac6e88e876161e12da0313 354 TIGRFAM TIGR01521 FruBisAldo_II_B: fructose-bisphosphate aldolase, class II, Calvin cycle subtype 3 349 1.6E-183 T 29-03-2018 IPR006412 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 CDC59_RS13340 ec13484546ac6e88e876161e12da0313 354 Gene3D G3DSA:3.20.20.70 1 331 1.1E-108 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS13340 ec13484546ac6e88e876161e12da0313 354 SUPERFAMILY SSF51569 3 329 2.2E-108 T 29-03-2018 CDC59_RS13340 ec13484546ac6e88e876161e12da0313 354 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 329 2.8E-100 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CDC59_RS13340 ec13484546ac6e88e876161e12da0313 354 Pfam PF01116 Fructose-bisphosphate aldolase class-II 4 328 4.2E-95 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CDC59_RS13340 ec13484546ac6e88e876161e12da0313 354 PIRSF PIRSF001359 1 329 6.2E-86 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CDC59_RS15230 f878d6d8d453c8f872a9f2750751fbe4 285 Pfam PF04773 FecR protein 76 167 3.1E-15 T 29-03-2018 IPR006860 FecR protein CDC59_RS15230 f878d6d8d453c8f872a9f2750751fbe4 285 PIRSF PIRSF018266 8 281 3.9E-58 T 29-03-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component CDC59_RS10580 40a6c8e4f40ff40194a9e620537f213b 119 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 40 88 1.7E-19 T 29-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CDC59_RS10580 40a6c8e4f40ff40194a9e620537f213b 119 Pfam PF02627 Carboxymuconolactone decarboxylase family 23 105 6.7E-21 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CDC59_RS10580 40a6c8e4f40ff40194a9e620537f213b 119 Gene3D G3DSA:1.20.1290.10 2 116 1.5E-24 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CDC59_RS10580 40a6c8e4f40ff40194a9e620537f213b 119 SUPERFAMILY SSF69118 4 110 9.95E-29 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CDC59_RS04545 6c054f8070e21c871809f0fe645cf006 264 SUPERFAMILY SSF48498 108 229 1.05E-23 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CDC59_RS04545 6c054f8070e21c871809f0fe645cf006 264 Gene3D G3DSA:1.10.260.40 63 98 1.1E-13 T 29-03-2018 CDC59_RS04545 6c054f8070e21c871809f0fe645cf006 264 SUPERFAMILY SSF46689 28 108 8.21E-19 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS04545 6c054f8070e21c871809f0fe645cf006 264 Pfam PF16859 Bacterial transcriptional repressor C-terminal 111 197 2.1E-11 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CDC59_RS04545 6c054f8070e21c871809f0fe645cf006 264 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 62 85 2.5E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDC59_RS04545 6c054f8070e21c871809f0fe645cf006 264 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 54 2.5E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDC59_RS04545 6c054f8070e21c871809f0fe645cf006 264 Pfam PF00440 Bacterial regulatory proteins, tetR family 41 87 2.5E-16 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDC59_RS04545 6c054f8070e21c871809f0fe645cf006 264 Gene3D G3DSA:1.10.357.10 99 232 1.2E-27 T 29-03-2018 CDC59_RS04545 6c054f8070e21c871809f0fe645cf006 264 Gene3D G3DSA:1.10.10.60 16 62 2.8E-17 T 29-03-2018 CDC59_RS12315 161b014f8d594b24505e0a5432e7b08a 193 PIRSF PIRSF006135 4 185 3.7E-55 T 29-03-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CDC59_RS12315 161b014f8d594b24505e0a5432e7b08a 193 SUPERFAMILY SSF52540 5 183 6.99E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS12315 161b014f8d594b24505e0a5432e7b08a 193 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 6 181 1.6E-61 T 29-03-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CDC59_RS12315 161b014f8d594b24505e0a5432e7b08a 193 Gene3D G3DSA:3.40.50.300 5 183 1.3E-63 T 29-03-2018 CDC59_RS17920 50218ba236bcd8ebdb61ed9d3cbcdc4c 451 Gene3D G3DSA:3.40.710.10 60 389 1.2E-57 T 29-03-2018 CDC59_RS17920 50218ba236bcd8ebdb61ed9d3cbcdc4c 451 SUPERFAMILY SSF56601 7 366 1.44E-75 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CDC59_RS17920 50218ba236bcd8ebdb61ed9d3cbcdc4c 451 Pfam PF00144 Beta-lactamase 75 358 2.0E-25 T 29-03-2018 IPR001466 Beta-lactamase-related CDC59_RS15620 4b09927e7bd87c0e7ecc17a121c4033d 388 Gene3D G3DSA:3.20.20.70 14 162 0.13 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS15620 4b09927e7bd87c0e7ecc17a121c4033d 388 Gene3D G3DSA:3.20.20.70 177 382 1.9E-29 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS15620 4b09927e7bd87c0e7ecc17a121c4033d 388 SUPERFAMILY SSF51391 167 380 1.44E-49 T 29-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CDC59_RS15620 4b09927e7bd87c0e7ecc17a121c4033d 388 Pfam PF02581 Thiamine monophosphate synthase 182 365 2.5E-48 T 29-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CDC59_RS23365 653acec9e6da4dadff219104736e1028 334 Gene3D G3DSA:3.30.1930.10 188 282 0.0014 T 29-03-2018 CDC59_RS23365 653acec9e6da4dadff219104736e1028 334 Pfam PF03864 Phage major capsid protein E 12 332 5.9E-102 T 29-03-2018 IPR005564 Major capsid protein GpE GO:0019028 CDC59_RS23365 653acec9e6da4dadff219104736e1028 334 Gene3D G3DSA:3.15.30.10 9 174 2.0E-10 T 29-03-2018 CDC59_RS23050 cb7b2564c426da07b4fe0a9063ca7fb0 416 Gene3D G3DSA:3.40.50.620 8 242 4.7E-29 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDC59_RS23050 cb7b2564c426da07b4fe0a9063ca7fb0 416 SUPERFAMILY SSF52402 9 242 3.75E-39 T 29-03-2018 CDC59_RS23050 cb7b2564c426da07b4fe0a9063ca7fb0 416 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 28 244 4.5E-18 T 29-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 CDC59_RS23050 cb7b2564c426da07b4fe0a9063ca7fb0 416 Pfam PF11922 Domain of unknown function (DUF3440) 246 352 2.6E-27 T 29-03-2018 IPR021845 Protein of unknown function DUF3440 CDC59_RS07495 7ea0fd0089217a370899d09750b11561 213 Pfam PF13417 Glutathione S-transferase, N-terminal domain 3 80 5.0E-14 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CDC59_RS07495 7ea0fd0089217a370899d09750b11561 213 SUPERFAMILY SSF52833 1 90 4.4E-23 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS07495 7ea0fd0089217a370899d09750b11561 213 Gene3D G3DSA:1.20.1050.10 98 213 1.7E-27 T 29-03-2018 CDC59_RS07495 7ea0fd0089217a370899d09750b11561 213 Pfam PF14497 Glutathione S-transferase, C-terminal domain 115 201 6.0E-7 T 29-03-2018 IPR004046 Glutathione S-transferase, C-terminal CDC59_RS07495 7ea0fd0089217a370899d09750b11561 213 Gene3D G3DSA:3.40.30.10 1 97 1.3E-28 T 29-03-2018 CDC59_RS07495 7ea0fd0089217a370899d09750b11561 213 TIGRFAM TIGR01262 maiA: maleylacetoacetate isomerase 2 211 9.6E-79 T 29-03-2018 IPR005955 Glutathione S-transferases, class Zeta GO:0003824|GO:0005737|GO:0009072 Reactome: R-HSA-156590|Reactome: R-HSA-71182 CDC59_RS07495 7ea0fd0089217a370899d09750b11561 213 SUPERFAMILY SSF47616 81 210 2.65E-30 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like CDC59_RS01750 0d6fd6d368e864ea58169a20e72688fe 192 Gene3D G3DSA:1.10.238.10 10 54 0.042 T 29-03-2018 CDC59_RS01750 0d6fd6d368e864ea58169a20e72688fe 192 SUPERFAMILY SSF47473 50 165 2.27E-26 T 29-03-2018 IPR011992 EF-hand domain pair CDC59_RS01750 0d6fd6d368e864ea58169a20e72688fe 192 Gene3D G3DSA:1.10.238.10 64 87 1.0E-7 T 29-03-2018 CDC59_RS01750 0d6fd6d368e864ea58169a20e72688fe 192 Gene3D G3DSA:1.10.1330.10 127 176 6.5E-12 T 29-03-2018 CDC59_RS01750 0d6fd6d368e864ea58169a20e72688fe 192 ProSitePatterns PS00018 EF-hand calcium-binding domain. 147 159 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site CDC59_RS01750 0d6fd6d368e864ea58169a20e72688fe 192 Gene3D G3DSA:1.10.238.10 88 126 4.5E-13 T 29-03-2018 CDC59_RS01750 0d6fd6d368e864ea58169a20e72688fe 192 Pfam PF13499 EF-hand domain pair 73 134 1.7E-11 T 29-03-2018 IPR002048 EF-hand domain GO:0005509 CDC59_RS01750 0d6fd6d368e864ea58169a20e72688fe 192 Gene3D G3DSA:1.10.238.10 55 63 0.012 T 29-03-2018 CDC59_RS01750 0d6fd6d368e864ea58169a20e72688fe 192 Pfam PF13202 EF hand 51 66 1.6E-4 T 29-03-2018 IPR002048 EF-hand domain GO:0005509 CDC59_RS01750 0d6fd6d368e864ea58169a20e72688fe 192 Pfam PF13202 EF hand 140 163 1.7E-5 T 29-03-2018 IPR002048 EF-hand domain GO:0005509 CDC59_RS01750 0d6fd6d368e864ea58169a20e72688fe 192 SMART SM00054 72 100 0.0081 T 29-03-2018 IPR002048 EF-hand domain GO:0005509 CDC59_RS01750 0d6fd6d368e864ea58169a20e72688fe 192 SMART SM00054 111 139 0.012 T 29-03-2018 IPR002048 EF-hand domain GO:0005509 CDC59_RS01750 0d6fd6d368e864ea58169a20e72688fe 192 SMART SM00054 140 166 1.1 T 29-03-2018 IPR002048 EF-hand domain GO:0005509 CDC59_RS01750 0d6fd6d368e864ea58169a20e72688fe 192 ProSitePatterns PS00018 EF-hand calcium-binding domain. 120 132 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site CDC59_RS01750 0d6fd6d368e864ea58169a20e72688fe 192 ProSitePatterns PS00018 EF-hand calcium-binding domain. 81 93 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site CDC59_RS18310 671ab82acc75c18b7acda6e30c690858 238 Pfam PF04055 Radical SAM superfamily 41 162 1.3E-13 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CDC59_RS18310 671ab82acc75c18b7acda6e30c690858 238 SUPERFAMILY SSF102114 38 220 1.57E-23 T 29-03-2018 CDC59_RS18310 671ab82acc75c18b7acda6e30c690858 238 Gene3D G3DSA:3.20.20.70 39 232 2.7E-23 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS18310 671ab82acc75c18b7acda6e30c690858 238 Pfam PF13353 4Fe-4S single cluster domain 36 110 2.9E-8 T 29-03-2018 CDC59_RS18310 671ab82acc75c18b7acda6e30c690858 238 TIGRFAM TIGR02495 NrdG2: anaerobic ribonucleoside-triphosphate reductase activating protein 23 208 9.7E-56 T 29-03-2018 IPR012840 Anaerobic ribonucleoside-triphosphate reductase activating protein CDC59_RS02690 76d345b92bc60b9c52a1a67cf657c454 202 Gene3D G3DSA:2.102.10.10 35 202 6.1E-37 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CDC59_RS02690 76d345b92bc60b9c52a1a67cf657c454 202 TIGRFAM TIGR01416 Rieske_proteo: ubiquinol-cytochrome c reductase, iron-sulfur subunit 11 195 9.0E-61 T 29-03-2018 IPR006317 Ubiquinol-cytochrome c reductase, iron-sulphur subunit GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 CDC59_RS02690 76d345b92bc60b9c52a1a67cf657c454 202 Pfam PF00355 Rieske [2Fe-2S] domain 54 182 2.5E-12 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CDC59_RS02690 76d345b92bc60b9c52a1a67cf657c454 202 Gene3D G3DSA:1.20.5.510 5 34 3.2E-12 T 29-03-2018 CDC59_RS02690 76d345b92bc60b9c52a1a67cf657c454 202 PRINTS PR00162 Rieske 2Fe-2S subunit signature 154 166 2.9E-7 T 29-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 CDC59_RS02690 76d345b92bc60b9c52a1a67cf657c454 202 PRINTS PR00162 Rieske 2Fe-2S subunit signature 124 135 2.9E-7 T 29-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 CDC59_RS02690 76d345b92bc60b9c52a1a67cf657c454 202 PRINTS PR00162 Rieske 2Fe-2S subunit signature 167 179 2.9E-7 T 29-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 CDC59_RS02690 76d345b92bc60b9c52a1a67cf657c454 202 Pfam PF10399 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal 1 40 1.2E-8 T 29-03-2018 IPR019470 Ubiquitinol-cytochrome C reductase, Fe-S subunit, TAT signal GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 CDC59_RS02690 76d345b92bc60b9c52a1a67cf657c454 202 SUPERFAMILY SSF50022 31 194 1.34E-36 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CDC59_RS10890 fe615e5394132f5d1c7c53c0b77912bc 724 Gene3D G3DSA:3.30.870.10 320 510 1.1E-22 T 29-03-2018 CDC59_RS10890 fe615e5394132f5d1c7c53c0b77912bc 724 PIRSF PIRSF015589 5 706 1.4E-264 T 29-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 CDC59_RS10890 fe615e5394132f5d1c7c53c0b77912bc 724 SUPERFAMILY SSF143724 112 317 4.71E-60 T 29-03-2018 CDC59_RS10890 fe615e5394132f5d1c7c53c0b77912bc 724 Hamap MF_00347 Polyphosphate kinase [ppk]. 7 693 28.912 T 29-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 CDC59_RS10890 fe615e5394132f5d1c7c53c0b77912bc 724 SUPERFAMILY SSF56024 319 506 6.28E-57 T 29-03-2018 CDC59_RS10890 fe615e5394132f5d1c7c53c0b77912bc 724 Gene3D G3DSA:3.30.1840.10 114 310 1.4E-56 T 29-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 CDC59_RS10890 fe615e5394132f5d1c7c53c0b77912bc 724 Pfam PF13090 Polyphosphate kinase C-terminal domain 334 684 3.9E-155 T 29-03-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 CDC59_RS10890 fe615e5394132f5d1c7c53c0b77912bc 724 Pfam PF13089 Polyphosphate kinase N-terminal domain 10 114 2.3E-33 T 29-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 CDC59_RS10890 fe615e5394132f5d1c7c53c0b77912bc 724 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 9 688 2.1E-292 T 29-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 CDC59_RS10890 fe615e5394132f5d1c7c53c0b77912bc 724 Gene3D G3DSA:3.30.870.10 511 698 4.4E-35 T 29-03-2018 CDC59_RS10890 fe615e5394132f5d1c7c53c0b77912bc 724 SUPERFAMILY SSF140356 9 110 4.05E-33 T 29-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 CDC59_RS10890 fe615e5394132f5d1c7c53c0b77912bc 724 SUPERFAMILY SSF56024 511 691 4.26E-70 T 29-03-2018 CDC59_RS10890 fe615e5394132f5d1c7c53c0b77912bc 724 Gene3D G3DSA:1.20.58.310 11 113 1.1E-32 T 29-03-2018 CDC59_RS10890 fe615e5394132f5d1c7c53c0b77912bc 724 Pfam PF02503 Polyphosphate kinase middle domain 124 324 3.4E-56 T 29-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 CDC59_RS09005 9f9ab2328be04433235338d6fbf0f93f 335 Pfam PF01380 SIS domain 149 272 1.5E-16 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CDC59_RS09005 9f9ab2328be04433235338d6fbf0f93f 335 SUPERFAMILY SSF46689 21 93 1.22E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS09005 9f9ab2328be04433235338d6fbf0f93f 335 Pfam PF01418 Helix-turn-helix domain, rpiR family 22 91 1.2E-12 T 29-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CDC59_RS09005 9f9ab2328be04433235338d6fbf0f93f 335 Gene3D G3DSA:1.10.10.10 16 96 9.2E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS09005 9f9ab2328be04433235338d6fbf0f93f 335 Gene3D G3DSA:3.40.50.10490 102 321 6.8E-28 T 29-03-2018 CDC59_RS09005 9f9ab2328be04433235338d6fbf0f93f 335 SUPERFAMILY SSF53697 115 279 5.56E-26 T 29-03-2018 CDC59_RS15560 f5d41f5fdaf976601900f96554baaedc 553 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 291 446 8.0E-34 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CDC59_RS15560 f5d41f5fdaf976601900f96554baaedc 553 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 180 280 6.7E-16 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CDC59_RS15560 f5d41f5fdaf976601900f96554baaedc 553 Gene3D G3DSA:1.20.140.10 282 456 5.6E-33 T 29-03-2018 CDC59_RS15560 f5d41f5fdaf976601900f96554baaedc 553 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 405 424 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CDC59_RS15560 f5d41f5fdaf976601900f96554baaedc 553 Gene3D G3DSA:2.40.110.10 174 281 6.7E-21 T 29-03-2018 CDC59_RS15560 f5d41f5fdaf976601900f96554baaedc 553 SUPERFAMILY SSF47203 296 449 1.27E-42 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CDC59_RS15560 f5d41f5fdaf976601900f96554baaedc 553 SUPERFAMILY SSF56645 54 298 1.1E-31 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CDC59_RS15765 3369dbfd8dbd09427cfa17cf2204151d 225 PIRSF PIRSF006324 4 225 1.4E-61 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CDC59_RS15765 3369dbfd8dbd09427cfa17cf2204151d 225 Pfam PF01810 LysE type translocator 19 222 4.5E-39 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CDC59_RS21410 dd00f2ff121cf90617f92befc12b4cef 403 SUPERFAMILY SSF48264 33 368 9.95E-42 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CDC59_RS21410 dd00f2ff121cf90617f92befc12b4cef 403 Pfam PF00067 Cytochrome P450 275 356 1.7E-9 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CDC59_RS21410 dd00f2ff121cf90617f92befc12b4cef 403 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 342 351 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CDC59_RS21410 dd00f2ff121cf90617f92befc12b4cef 403 Gene3D G3DSA:1.10.630.10 214 369 3.2E-26 T 29-03-2018 CDC59_RS21410 dd00f2ff121cf90617f92befc12b4cef 403 Gene3D G3DSA:1.10.630.10 30 213 4.1E-5 T 29-03-2018 CDC59_RS00535 5f723dac39880a66552a82dcb63655fe 29 Pfam PF09604 F subunit of K+-transporting ATPase (Potass_KdpF) 6 29 2.0E-11 T 29-03-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 CDC59_RS00535 5f723dac39880a66552a82dcb63655fe 29 TIGRFAM TIGR02115 potass_kdpF: K+-transporting ATPase, F subunit 7 29 5.9E-12 T 29-03-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 CDC59_RS20125 a6c90fed4d4096cc889ba88388bf5d71 169 Gene3D G3DSA:1.10.10.10 79 164 1.6E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS20125 a6c90fed4d4096cc889ba88388bf5d71 169 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 19 161 4.0E-17 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS20125 a6c90fed4d4096cc889ba88388bf5d71 169 Pfam PF04542 Sigma-70 region 2 15 80 5.0E-9 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS20125 a6c90fed4d4096cc889ba88388bf5d71 169 SUPERFAMILY SSF88659 104 164 7.85E-13 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS20125 a6c90fed4d4096cc889ba88388bf5d71 169 Pfam PF08281 Sigma-70, region 4 112 163 5.6E-15 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS20125 a6c90fed4d4096cc889ba88388bf5d71 169 SUPERFAMILY SSF88946 12 77 1.77E-9 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS20125 a6c90fed4d4096cc889ba88388bf5d71 169 Gene3D G3DSA:1.10.1740.10 8 78 6.0E-10 T 29-03-2018 CDC59_RS02840 7c201f63f6220d135a174115712d1214 364 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 364 2.3E-153 T 29-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CDC59_RS02840 7c201f63f6220d135a174115712d1214 364 Gene3D G3DSA:3.10.20.30 264 363 1.0E-43 T 29-03-2018 IPR012675 Beta-grasp domain CDC59_RS02840 7c201f63f6220d135a174115712d1214 364 Pfam PF01926 50S ribosome-binding GTPase 5 115 3.1E-22 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CDC59_RS02840 7c201f63f6220d135a174115712d1214 364 SUPERFAMILY SSF52540 3 302 8.07E-84 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS02840 7c201f63f6220d135a174115712d1214 364 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 364 43.922 T 29-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CDC59_RS02840 7c201f63f6220d135a174115712d1214 364 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 4.4E-34 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CDC59_RS02840 7c201f63f6220d135a174115712d1214 364 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 4.4E-34 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CDC59_RS02840 7c201f63f6220d135a174115712d1214 364 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 4.4E-34 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CDC59_RS02840 7c201f63f6220d135a174115712d1214 364 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 4.4E-34 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CDC59_RS02840 7c201f63f6220d135a174115712d1214 364 Pfam PF06071 Protein of unknown function (DUF933) 280 363 9.7E-38 T 29-03-2018 IPR013029 Domain of unknown function DUF933 Reactome: R-HSA-114608 CDC59_RS02840 7c201f63f6220d135a174115712d1214 364 Gene3D G3DSA:3.40.50.300 2 46 3.1E-8 T 29-03-2018 CDC59_RS02840 7c201f63f6220d135a174115712d1214 364 SUPERFAMILY SSF81271 280 360 1.37E-34 T 29-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CDC59_RS02840 7c201f63f6220d135a174115712d1214 364 PIRSF PIRSF006641 1 364 1.6E-151 T 29-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CDC59_RS02840 7c201f63f6220d135a174115712d1214 364 Gene3D G3DSA:1.10.150.300 110 201 5.9E-27 T 29-03-2018 IPR023192 TGS-like domain Reactome: R-HSA-114608 CDC59_RS07985 598b12c26ba6ae6fc714a13b9323d614 448 Pfam PF01554 MatE 241 401 1.6E-26 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CDC59_RS07985 598b12c26ba6ae6fc714a13b9323d614 448 Pfam PF01554 MatE 15 173 4.2E-24 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CDC59_RS07985 598b12c26ba6ae6fc714a13b9323d614 448 PIRSF PIRSF006603 6 448 3.9E-50 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CDC59_RS07985 598b12c26ba6ae6fc714a13b9323d614 448 TIGRFAM TIGR00797 matE: MATE efflux family protein 15 408 1.0E-70 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CDC59_RS05415 8be59b9b2f1350808731134cc4481cd8 73 Gene3D G3DSA:3.40.50.2300 1 62 1.7E-5 T 29-03-2018 CDC59_RS05415 8be59b9b2f1350808731134cc4481cd8 73 SUPERFAMILY SSF53822 1 47 4.71E-6 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CDC59_RS00755 d691de2d0db357a797b10387efa5dd4f 719 Pfam PF05593 RHS Repeat 636 671 2.1E-8 T 29-03-2018 IPR031325 RHS repeat CDC59_RS00755 d691de2d0db357a797b10387efa5dd4f 719 Pfam PF05593 RHS Repeat 428 465 4.4E-7 T 29-03-2018 IPR031325 RHS repeat CDC59_RS00755 d691de2d0db357a797b10387efa5dd4f 719 Pfam PF05593 RHS Repeat 291 328 4.2E-8 T 29-03-2018 IPR031325 RHS repeat CDC59_RS00755 d691de2d0db357a797b10387efa5dd4f 719 Pfam PF05593 RHS Repeat 657 694 4.8E-6 T 29-03-2018 IPR031325 RHS repeat CDC59_RS00755 d691de2d0db357a797b10387efa5dd4f 719 Pfam PF05593 RHS Repeat 590 628 1.0E-8 T 29-03-2018 IPR031325 RHS repeat CDC59_RS00755 d691de2d0db357a797b10387efa5dd4f 719 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 249 287 2.2E-6 T 29-03-2018 IPR006530 YD repeat CDC59_RS00755 d691de2d0db357a797b10387efa5dd4f 719 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 636 677 2.3E-7 T 29-03-2018 IPR006530 YD repeat CDC59_RS00755 d691de2d0db357a797b10387efa5dd4f 719 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 590 623 1.1E-4 T 29-03-2018 IPR006530 YD repeat CDC59_RS00755 d691de2d0db357a797b10387efa5dd4f 719 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 291 331 1.1E-6 T 29-03-2018 IPR006530 YD repeat CDC59_RS02390 b767c02e08d592cb51b96bd516a0282e 233 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 12 207 26.534 T 29-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 CDC59_RS02390 b767c02e08d592cb51b96bd516a0282e 233 Pfam PF01926 50S ribosome-binding GTPase 26 150 3.6E-17 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CDC59_RS02390 b767c02e08d592cb51b96bd516a0282e 233 SUPERFAMILY SSF52540 15 206 3.08E-30 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS02390 b767c02e08d592cb51b96bd516a0282e 233 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 7 203 6.9E-63 T 29-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 CDC59_RS02390 b767c02e08d592cb51b96bd516a0282e 233 Gene3D G3DSA:3.40.50.300 3 214 2.9E-24 T 29-03-2018 CDC59_RS08935 dfdea3f79214dc6474c285bd0cdd7c40 309 Gene3D G3DSA:3.40.190.10 176 264 1.1E-26 T 29-03-2018 CDC59_RS08935 dfdea3f79214dc6474c285bd0cdd7c40 309 Gene3D G3DSA:3.40.190.10 88 175 4.4E-17 T 29-03-2018 CDC59_RS08935 dfdea3f79214dc6474c285bd0cdd7c40 309 Pfam PF03466 LysR substrate binding domain 90 291 1.4E-48 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS08935 dfdea3f79214dc6474c285bd0cdd7c40 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 4.0E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS08935 dfdea3f79214dc6474c285bd0cdd7c40 309 SUPERFAMILY SSF46785 3 111 2.94E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS08935 dfdea3f79214dc6474c285bd0cdd7c40 309 Gene3D G3DSA:1.10.10.10 2 84 1.3E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS08935 dfdea3f79214dc6474c285bd0cdd7c40 309 SUPERFAMILY SSF53850 91 297 1.81E-50 T 29-03-2018 CDC59_RS09115 095d7277ab69acfddb02fd3349a6e204 403 SMART SM00771 249 378 2.1E-36 T 29-03-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 CDC59_RS09115 095d7277ab69acfddb02fd3349a6e204 403 ProDom PD035754 CELL DIVISION MEMBRANE ZIPA SEPTATION TRANSMEMBRANE HOMOLOG INNER CYCLE ZIPA 255 378 2.0E-7 T 29-03-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 CDC59_RS09115 095d7277ab69acfddb02fd3349a6e204 403 Gene3D G3DSA:3.30.1400.10 250 381 8.8E-25 T 29-03-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 CDC59_RS09115 095d7277ab69acfddb02fd3349a6e204 403 SUPERFAMILY SSF64383 248 385 4.97E-25 T 29-03-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 CDC59_RS09115 095d7277ab69acfddb02fd3349a6e204 403 Pfam PF04354 ZipA, C-terminal FtsZ-binding domain 254 376 2.3E-11 T 29-03-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 CDC59_RS18590 36ee259961f84b6f436f979380a6d956 249 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS18590 36ee259961f84b6f436f979380a6d956 249 Gene3D G3DSA:3.40.50.300 1 239 1.1E-72 T 29-03-2018 CDC59_RS18590 36ee259961f84b6f436f979380a6d956 249 SMART SM00382 30 217 1.3E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS18590 36ee259961f84b6f436f979380a6d956 249 Pfam PF00005 ABC transporter 21 169 1.1E-36 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS18590 36ee259961f84b6f436f979380a6d956 249 PIRSF PIRSF039085 2 246 1.5E-99 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CDC59_RS18590 36ee259961f84b6f436f979380a6d956 249 SUPERFAMILY SSF52540 5 230 7.64E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS13910 e8eb99cbaa0f9f13cf58c635718867b9 248 Gene3D G3DSA:3.60.10.10 1 246 3.3E-32 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CDC59_RS13910 e8eb99cbaa0f9f13cf58c635718867b9 248 SUPERFAMILY SSF56219 2 245 1.16E-49 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CDC59_RS13910 e8eb99cbaa0f9f13cf58c635718867b9 248 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 7 238 5.7E-17 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CDC59_RS23910 d564c5f13f801f3671f3bcaaae02b0c0 323 Pfam PF03631 Virulence factor BrkB 30 287 3.3E-47 T 29-03-2018 IPR017039 Virulence factor BrkB CDC59_RS23910 d564c5f13f801f3671f3bcaaae02b0c0 323 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 24 282 4.2E-25 T 29-03-2018 IPR017039 Virulence factor BrkB CDC59_RS23910 d564c5f13f801f3671f3bcaaae02b0c0 323 PIRSF PIRSF035875 7 303 1.1E-69 T 29-03-2018 IPR017039 Virulence factor BrkB CDC59_RS04955 772b9c33f7e17a98ec3d95f51e2aafd3 280 Pfam PF00085 Thioredoxin 4 104 9.7E-27 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 CDC59_RS04955 772b9c33f7e17a98ec3d95f51e2aafd3 280 Pfam PF14561 Tetratricopeptide repeat 193 279 3.8E-23 T 29-03-2018 CDC59_RS04955 772b9c33f7e17a98ec3d95f51e2aafd3 280 Pfam PF14559 Tetratricopeptide repeat 122 187 2.9E-6 T 29-03-2018 CDC59_RS04955 772b9c33f7e17a98ec3d95f51e2aafd3 280 ProSitePatterns PS00194 Thioredoxin family active site. 23 41 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CDC59_RS04955 772b9c33f7e17a98ec3d95f51e2aafd3 280 PRINTS PR00421 Thioredoxin family signature 22 30 2.2E-5 T 29-03-2018 CDC59_RS04955 772b9c33f7e17a98ec3d95f51e2aafd3 280 PRINTS PR00421 Thioredoxin family signature 30 39 2.2E-5 T 29-03-2018 CDC59_RS04955 772b9c33f7e17a98ec3d95f51e2aafd3 280 PRINTS PR00421 Thioredoxin family signature 70 81 2.2E-5 T 29-03-2018 CDC59_RS04955 772b9c33f7e17a98ec3d95f51e2aafd3 280 Gene3D G3DSA:1.25.40.10 204 280 1.4E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS04955 772b9c33f7e17a98ec3d95f51e2aafd3 280 TIGRFAM TIGR01068 thioredoxin: thioredoxin 5 104 2.0E-31 T 29-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CDC59_RS04955 772b9c33f7e17a98ec3d95f51e2aafd3 280 Gene3D G3DSA:3.40.30.10 1 103 1.7E-30 T 29-03-2018 CDC59_RS04955 772b9c33f7e17a98ec3d95f51e2aafd3 280 SMART SM00028 110 143 0.35 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CDC59_RS04955 772b9c33f7e17a98ec3d95f51e2aafd3 280 SMART SM00028 213 246 43.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CDC59_RS04955 772b9c33f7e17a98ec3d95f51e2aafd3 280 SUPERFAMILY SSF52833 3 108 4.59E-36 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS04955 772b9c33f7e17a98ec3d95f51e2aafd3 280 Gene3D G3DSA:1.25.40.10 104 203 4.2E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS04955 772b9c33f7e17a98ec3d95f51e2aafd3 280 SUPERFAMILY SSF48452 194 243 8.26E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS04955 772b9c33f7e17a98ec3d95f51e2aafd3 280 SUPERFAMILY SSF48452 114 167 8.26E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS20590 1b33d1164cab1f4c7fe70dcf4c09834b 424 Pfam PF05707 Zonular occludens toxin (Zot) 1 212 5.4E-19 T 29-03-2018 IPR008900 Zona occludens toxin CDC59_RS20590 1b33d1164cab1f4c7fe70dcf4c09834b 424 Gene3D G3DSA:3.40.50.300 2 214 1.5E-8 T 29-03-2018 CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 Pfam PF13018 Extended Signal Peptide of Type V secretion system 1 25 1.5E-6 T 29-03-2018 IPR024973 ESPR domain CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 822 852 0.043 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 555 589 0.058 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1786 1827 1.7 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 885 913 0.33 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 957 977 0.37 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1109 1146 5.2E-4 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1256 1279 1.3 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 856 884 0.0086 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 653 691 0.24 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 718 754 3.2E-4 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 979 1014 0.0041 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 630 668 1.5E-4 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 467 504 1.2E-4 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1022 1065 0.006 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 589 629 5.3E-4 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1436 1469 0.15 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1766 1786 0.42 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 505 545 1.1E-5 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 755 795 3.0E-7 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1533 1551 2.4 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1127 1167 0.018 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 796 838 0.0011 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 356 387 2.0 T 29-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 SMART SM00912 87 208 1.4E-40 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 Pfam PF13332 Haemagluttinin repeat 2180 2264 8.2E-7 T 29-03-2018 IPR025157 Hemagglutinin repeat CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 Pfam PF13332 Haemagluttinin repeat 2325 2497 5.8E-45 T 29-03-2018 IPR025157 Hemagglutinin repeat CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 Pfam PF13332 Haemagluttinin repeat 1926 1992 1.3E-11 T 29-03-2018 IPR025157 Hemagglutinin repeat CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 Pfam PF13332 Haemagluttinin repeat 2009 2162 1.1E-4 T 29-03-2018 IPR025157 Hemagglutinin repeat CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 Pfam PF05860 haemagglutination activity domain 72 204 6.6E-31 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 Gene3D G3DSA:2.160.20.10 1082 1297 0.012 T 29-03-2018 IPR012334 Pectin lyase fold CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 Gene3D G3DSA:2.160.20.10 2082 2262 0.026 T 29-03-2018 IPR012334 Pectin lyase fold CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 Pfam PF05594 Haemagluttinin repeat 576 629 0.066 T 29-03-2018 IPR008619 Filamentous haemagglutinin repeat CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 Pfam PF05594 Haemagluttinin repeat 1004 1046 7.5 T 29-03-2018 IPR008619 Filamentous haemagglutinin repeat CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 Pfam PF05594 Haemagluttinin repeat 843 905 0.042 T 29-03-2018 IPR008619 Filamentous haemagglutinin repeat CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 Pfam PF05594 Haemagluttinin repeat 256 353 7.7E-5 T 29-03-2018 IPR008619 Filamentous haemagglutinin repeat CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 Pfam PF05594 Haemagluttinin repeat 470 567 0.0089 T 29-03-2018 IPR008619 Filamentous haemagglutinin repeat CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 Pfam PF05594 Haemagluttinin repeat 719 795 0.24 T 29-03-2018 IPR008619 Filamentous haemagglutinin repeat CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 Pfam PF05594 Haemagluttinin repeat 1760 1811 43.0 T 29-03-2018 IPR008619 Filamentous haemagglutinin repeat CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 Pfam PF05594 Haemagluttinin repeat 380 453 4.2 T 29-03-2018 IPR008619 Filamentous haemagglutinin repeat CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 Pfam PF05594 Haemagluttinin repeat 1107 1167 0.049 T 29-03-2018 IPR008619 Filamentous haemagglutinin repeat CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 TIGRFAM TIGR01901 adhes_NPXG: filamentous hemagglutinin family N-terminal domain 106 201 5.6E-22 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 SUPERFAMILY SSF51126 80 357 2.98E-65 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 Gene3D G3DSA:2.160.20.10 641 770 0.0015 T 29-03-2018 IPR012334 Pectin lyase fold CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 Gene3D G3DSA:2.160.20.10 771 940 6.1E-4 T 29-03-2018 IPR012334 Pectin lyase fold CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 Gene3D G3DSA:2.160.20.10 941 1022 0.003 T 29-03-2018 IPR012334 Pectin lyase fold CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 Gene3D G3DSA:2.160.20.10 457 515 0.021 T 29-03-2018 IPR012334 Pectin lyase fold CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 Gene3D G3DSA:2.160.20.10 1023 1081 0.06 T 29-03-2018 IPR012334 Pectin lyase fold CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 Gene3D G3DSA:2.160.20.10 516 640 6.0E-7 T 29-03-2018 IPR012334 Pectin lyase fold CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 Gene3D G3DSA:2.160.20.10 1524 1824 0.053 T 29-03-2018 IPR012334 Pectin lyase fold CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 Gene3D G3DSA:2.160.20.10 74 365 1.3E-59 T 29-03-2018 IPR012334 Pectin lyase fold CDC59_RS22025 70d7acc26881126d2f457fd1ce3f7281 3095 Gene3D G3DSA:2.160.20.10 366 456 2.7E-6 T 29-03-2018 IPR012334 Pectin lyase fold CDC59_RS04990 f6ba5da2092e1912bde8917e390f5365 938 PIRSF PIRSF035905 1 938 1.5E-260 T 29-03-2018 IPR014600 Uncharacterised conserved protein UCP035905, membrane protein CDC59_RS04990 f6ba5da2092e1912bde8917e390f5365 938 Pfam PF10101 Predicted membrane protein (DUF2339) 169 929 1.7E-165 T 29-03-2018 IPR019286 Protein of unknown function DUF2339, transmembrane CDC59_RS00930 f551e549c60f84fad884214e3458a4c4 768 Pfam PF00270 DEAD/DEAH box helicase 245 388 4.3E-10 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CDC59_RS00930 f551e549c60f84fad884214e3458a4c4 768 Pfam PF00271 Helicase conserved C-terminal domain 540 623 1.5E-6 T 29-03-2018 IPR001650 Helicase, C-terminal CDC59_RS00930 f551e549c60f84fad884214e3458a4c4 768 SMART SM00487 218 421 1.3E-13 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CDC59_RS00930 f551e549c60f84fad884214e3458a4c4 768 Gene3D G3DSA:3.40.50.300 418 651 1.9E-19 T 29-03-2018 CDC59_RS00930 f551e549c60f84fad884214e3458a4c4 768 Hamap MF_00983 Probable primosomal protein N' [priA]. 25 768 23.198 T 29-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 CDC59_RS00930 f551e549c60f84fad884214e3458a4c4 768 Gene3D G3DSA:3.40.50.300 219 390 3.5E-23 T 29-03-2018 CDC59_RS00930 f551e549c60f84fad884214e3458a4c4 768 SUPERFAMILY SSF52540 538 652 2.49E-25 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS00930 f551e549c60f84fad884214e3458a4c4 768 SUPERFAMILY SSF52540 245 295 2.49E-25 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS00930 f551e549c60f84fad884214e3458a4c4 768 TIGRFAM TIGR00595 priA: primosomal protein N' 246 766 5.9E-167 T 29-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 CDC59_RS00930 f551e549c60f84fad884214e3458a4c4 768 SUPERFAMILY SSF52540 201 402 2.06E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS00930 f551e549c60f84fad884214e3458a4c4 768 SMART SM00490 526 623 7.4E-8 T 29-03-2018 IPR001650 Helicase, C-terminal CDC59_RS18035 760a8a9417a9f5602682e6b476629419 113 SUPERFAMILY SSF57783 3 36 5.27E-14 T 29-03-2018 CDC59_RS18035 760a8a9417a9f5602682e6b476629419 113 Pfam PF03831 PhnA domain 47 113 1.1E-32 T 29-03-2018 IPR013988 PhnA protein, C-terminal CDC59_RS18035 760a8a9417a9f5602682e6b476629419 113 SUPERFAMILY SSF82057 43 113 1.14E-27 T 29-03-2018 CDC59_RS18035 760a8a9417a9f5602682e6b476629419 113 Gene3D G3DSA:2.30.30.40 45 112 1.5E-35 T 29-03-2018 CDC59_RS18035 760a8a9417a9f5602682e6b476629419 113 TIGRFAM TIGR00686 phnA: putative alkylphosphonate utilization operon protein PhnA 4 112 1.4E-46 T 29-03-2018 IPR004624 PhnA protein CDC59_RS18035 760a8a9417a9f5602682e6b476629419 113 Gene3D G3DSA:2.20.25.10 2 40 9.4E-18 T 29-03-2018 CDC59_RS18035 760a8a9417a9f5602682e6b476629419 113 Pfam PF08274 PhnA Zinc-Ribbon 3 32 4.8E-16 T 29-03-2018 IPR013987 PhnA protein, N-terminal CDC59_RS03230 85d14ea03502174f2b69babeb5c8105d 425 SMART SM01091 341 419 6.4E-21 T 29-03-2018 IPR005170 Transporter-associated domain CDC59_RS03230 85d14ea03502174f2b69babeb5c8105d 425 Gene3D G3DSA:3.10.580.10 187 336 3.9E-27 T 29-03-2018 CDC59_RS03230 85d14ea03502174f2b69babeb5c8105d 425 Pfam PF01595 Domain of unknown function DUF21 12 183 2.2E-43 T 29-03-2018 IPR002550 Domain of unknown function DUF21 CDC59_RS03230 85d14ea03502174f2b69babeb5c8105d 425 SUPERFAMILY SSF54631 197 332 4.03E-26 T 29-03-2018 CDC59_RS03230 85d14ea03502174f2b69babeb5c8105d 425 Pfam PF03471 Transporter associated domain 344 417 3.8E-14 T 29-03-2018 IPR005170 Transporter-associated domain CDC59_RS03230 85d14ea03502174f2b69babeb5c8105d 425 Pfam PF00571 CBS domain 278 326 1.3E-4 T 29-03-2018 IPR000644 CBS domain CDC59_RS03230 85d14ea03502174f2b69babeb5c8105d 425 Pfam PF00571 CBS domain 206 263 5.1E-4 T 29-03-2018 IPR000644 CBS domain CDC59_RS03230 85d14ea03502174f2b69babeb5c8105d 425 SUPERFAMILY SSF56176 344 422 2.07E-17 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CDC59_RS03230 85d14ea03502174f2b69babeb5c8105d 425 Gene3D G3DSA:3.30.465.10 339 418 5.1E-16 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CDC59_RS00025 5ddef9db64a0954c70da678f027ee2b3 474 Gene3D G3DSA:1.20.120.430 137 294 8.8E-24 T 29-03-2018 CDC59_RS00025 5ddef9db64a0954c70da678f027ee2b3 474 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 17 474 32.356 T 29-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 CDC59_RS00025 5ddef9db64a0954c70da678f027ee2b3 474 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 23 474 3.7E-98 T 29-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 CDC59_RS00025 5ddef9db64a0954c70da678f027ee2b3 474 Pfam PF01926 50S ribosome-binding GTPase 234 355 5.0E-24 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CDC59_RS00025 5ddef9db64a0954c70da678f027ee2b3 474 SUPERFAMILY SSF52540 83 185 1.38E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS00025 5ddef9db64a0954c70da678f027ee2b3 474 SUPERFAMILY SSF52540 219 392 1.38E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS00025 5ddef9db64a0954c70da678f027ee2b3 474 Gene3D G3DSA:3.30.1360.120 8 136 6.5E-44 T 29-03-2018 CDC59_RS00025 5ddef9db64a0954c70da678f027ee2b3 474 Gene3D G3DSA:1.20.120.430 295 474 2.5E-33 T 29-03-2018 CDC59_RS00025 5ddef9db64a0954c70da678f027ee2b3 474 Pfam PF12631 MnmE helical domain 138 471 3.7E-56 T 29-03-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 CDC59_RS00025 5ddef9db64a0954c70da678f027ee2b3 474 Pfam PF10396 GTP-binding protein TrmE N-terminus 18 135 1.7E-38 T 29-03-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 CDC59_RS00025 5ddef9db64a0954c70da678f027ee2b3 474 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 301 319 1.5E-5 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CDC59_RS00025 5ddef9db64a0954c70da678f027ee2b3 474 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 234 254 1.5E-5 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CDC59_RS00025 5ddef9db64a0954c70da678f027ee2b3 474 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 233 362 1.1E-20 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CDC59_RS23695 80afd0d8ea9a77441303ab2e26da4f42 339 TIGRFAM TIGR02634 xylF: D-xylose ABC transporter, D-xylose-binding protein 35 336 1.9E-143 T 29-03-2018 IPR013456 D-xylose ABC transporter, substrate-binding protein GO:0015753|GO:0048029 CDC59_RS23695 80afd0d8ea9a77441303ab2e26da4f42 339 SUPERFAMILY SSF53822 33 323 8.88E-73 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CDC59_RS23695 80afd0d8ea9a77441303ab2e26da4f42 339 Gene3D G3DSA:3.40.50.2300 25 138 5.5E-22 T 29-03-2018 CDC59_RS23695 80afd0d8ea9a77441303ab2e26da4f42 339 Pfam PF13407 Periplasmic binding protein domain 36 292 2.9E-64 T 29-03-2018 IPR025997 Periplasmic binding protein CDC59_RS23695 80afd0d8ea9a77441303ab2e26da4f42 339 Gene3D G3DSA:3.40.50.2300 139 336 4.8E-38 T 29-03-2018 CDC59_RS02890 e79a1b0f0435b3bc5f65841065f6edd1 266 Pfam PF03167 Uracil DNA glycosylase superfamily 87 249 3.3E-22 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CDC59_RS02890 e79a1b0f0435b3bc5f65841065f6edd1 266 SMART SM00986 82 250 1.1E-35 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CDC59_RS02890 e79a1b0f0435b3bc5f65841065f6edd1 266 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 90 99 - T 29-03-2018 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CDC59_RS02890 e79a1b0f0435b3bc5f65841065f6edd1 266 SMART SM00987 82 250 1.1E-35 T 29-03-2018 CDC59_RS02890 e79a1b0f0435b3bc5f65841065f6edd1 266 SUPERFAMILY SSF52141 38 260 4.8E-76 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CDC59_RS02890 e79a1b0f0435b3bc5f65841065f6edd1 266 Gene3D G3DSA:3.40.470.10 29 265 1.9E-85 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CDC59_RS02890 e79a1b0f0435b3bc5f65841065f6edd1 266 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 39 261 37.491 T 29-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CDC59_RS02890 e79a1b0f0435b3bc5f65841065f6edd1 266 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 41 254 1.1E-67 T 29-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CDC59_RS20540 39c8abf95941e19c87738d577f5892b2 260 SUPERFAMILY SSF51735 12 258 2.5E-62 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS20540 39c8abf95941e19c87738d577f5892b2 260 PIRSF PIRSF000094 7 260 1.8E-83 T 29-03-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CDC59_RS20540 39c8abf95941e19c87738d577f5892b2 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 256 2.7E-79 T 29-03-2018 CDC59_RS20540 39c8abf95941e19c87738d577f5892b2 260 Gene3D G3DSA:3.40.50.720 6 260 7.1E-43 T 29-03-2018 CDC59_RS20540 39c8abf95941e19c87738d577f5892b2 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 1.4E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS20540 39c8abf95941e19c87738d577f5892b2 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 1.4E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS20540 39c8abf95941e19c87738d577f5892b2 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 1.4E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS20540 39c8abf95941e19c87738d577f5892b2 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 1.4E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS19840 7563f5848c2ad52f280db1740dcf4636 181 Gene3D G3DSA:1.10.260.40 2 72 6.0E-13 T 29-03-2018 CDC59_RS19840 7563f5848c2ad52f280db1740dcf4636 181 SMART SM00530 7 62 3.7E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDC59_RS19840 7563f5848c2ad52f280db1740dcf4636 181 Pfam PF01381 Helix-turn-helix 9 58 3.0E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDC59_RS19840 7563f5848c2ad52f280db1740dcf4636 181 SUPERFAMILY SSF47413 6 59 2.68E-12 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDC59_RS01770 a9367469fa0830c128e2ba332fede365 664 SUPERFAMILY SSF52743 484 646 2.1E-38 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CDC59_RS01770 a9367469fa0830c128e2ba332fede365 664 SUPERFAMILY SSF52743 101 326 2.1E-38 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CDC59_RS01770 a9367469fa0830c128e2ba332fede365 664 PRINTS PR00723 Subtilisin serine protease family (S8) signature 586 602 5.5E-6 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CDC59_RS01770 a9367469fa0830c128e2ba332fede365 664 PRINTS PR00723 Subtilisin serine protease family (S8) signature 166 185 5.5E-6 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CDC59_RS01770 a9367469fa0830c128e2ba332fede365 664 Gene3D G3DSA:3.40.50.200 154 652 1.7E-40 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CDC59_RS01770 a9367469fa0830c128e2ba332fede365 664 Pfam PF00082 Subtilase family 490 637 6.9E-11 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CDC59_RS14255 32e3ffcd8f63728a2c4ee6eaf21708bc 108 Pfam PF07769 psiF repeat 76 107 5.8E-12 T 29-03-2018 IPR011690 Phosphate-starvation-induced PsiF repeat CDC59_RS14255 32e3ffcd8f63728a2c4ee6eaf21708bc 108 Pfam PF07769 psiF repeat 35 65 2.0E-8 T 29-03-2018 IPR011690 Phosphate-starvation-induced PsiF repeat CDC59_RS19320 76c401ba03c1c189133e14714bdcae78 259 SUPERFAMILY SSF52096 4 242 9.95E-66 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CDC59_RS19320 76c401ba03c1c189133e14714bdcae78 259 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 101 121 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CDC59_RS19320 76c401ba03c1c189133e14714bdcae78 259 Gene3D G3DSA:3.90.226.10 2 251 1.8E-59 T 29-03-2018 CDC59_RS19320 76c401ba03c1c189133e14714bdcae78 259 Pfam PF00378 Enoyl-CoA hydratase/isomerase 12 227 9.3E-36 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CDC59_RS14325 9300e07ccc74f3caa19db826eb4748fa 82 Gene3D G3DSA:3.30.70.20 2 50 9.2E-15 T 29-03-2018 CDC59_RS14325 9300e07ccc74f3caa19db826eb4748fa 82 SUPERFAMILY SSF54862 4 76 2.45E-19 T 29-03-2018 CDC59_RS14325 9300e07ccc74f3caa19db826eb4748fa 82 Gene3D G3DSA:3.30.70.20 51 78 0.052 T 29-03-2018 CDC59_RS14325 9300e07ccc74f3caa19db826eb4748fa 82 Pfam PF12838 4Fe-4S dicluster domain 9 57 2.1E-6 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CDC59_RS14325 9300e07ccc74f3caa19db826eb4748fa 82 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 9 20 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CDC59_RS01325 27723612c44b63299351d8b38b6fb721 725 Pfam PF05593 RHS Repeat 254 290 1.9E-7 T 29-03-2018 IPR031325 RHS repeat CDC59_RS01325 27723612c44b63299351d8b38b6fb721 725 Pfam PF05593 RHS Repeat 642 677 5.8E-9 T 29-03-2018 IPR031325 RHS repeat CDC59_RS01325 27723612c44b63299351d8b38b6fb721 725 Pfam PF05593 RHS Repeat 596 630 1.0E-8 T 29-03-2018 IPR031325 RHS repeat CDC59_RS01325 27723612c44b63299351d8b38b6fb721 725 Pfam PF05593 RHS Repeat 296 332 1.6E-9 T 29-03-2018 IPR031325 RHS repeat CDC59_RS01325 27723612c44b63299351d8b38b6fb721 725 Pfam PF05593 RHS Repeat 663 700 5.9E-6 T 29-03-2018 IPR031325 RHS repeat CDC59_RS01325 27723612c44b63299351d8b38b6fb721 725 Pfam PF05593 RHS Repeat 433 470 4.5E-7 T 29-03-2018 IPR031325 RHS repeat CDC59_RS01325 27723612c44b63299351d8b38b6fb721 725 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 596 629 1.2E-4 T 29-03-2018 IPR006530 YD repeat CDC59_RS01325 27723612c44b63299351d8b38b6fb721 725 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 634 662 8.9E-5 T 29-03-2018 IPR006530 YD repeat CDC59_RS01325 27723612c44b63299351d8b38b6fb721 725 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 296 336 2.4E-8 T 29-03-2018 IPR006530 YD repeat CDC59_RS01325 27723612c44b63299351d8b38b6fb721 725 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 254 294 7.8E-6 T 29-03-2018 IPR006530 YD repeat CDC59_RS19175 1600343483cda5226f20afcd39475688 537 SUPERFAMILY SSF56281 456 488 3.14E-19 T 29-03-2018 IPR001279 Metallo-beta-lactamase CDC59_RS19175 1600343483cda5226f20afcd39475688 537 SUPERFAMILY SSF56281 249 426 3.14E-19 T 29-03-2018 IPR001279 Metallo-beta-lactamase CDC59_RS19175 1600343483cda5226f20afcd39475688 537 Gene3D G3DSA:3.60.15.10 212 497 3.3E-24 T 29-03-2018 IPR001279 Metallo-beta-lactamase CDC59_RS19175 1600343483cda5226f20afcd39475688 537 Pfam PF12706 Beta-lactamase superfamily domain 270 423 3.5E-10 T 29-03-2018 IPR001279 Metallo-beta-lactamase CDC59_RS20135 34ae2036392ee418c1f87b8b9cf6c795 174 SUPERFAMILY SSF46894 96 163 8.16E-20 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CDC59_RS20135 34ae2036392ee418c1f87b8b9cf6c795 174 SMART SM00421 104 161 1.4E-22 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS20135 34ae2036392ee418c1f87b8b9cf6c795 174 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 121 137 2.0E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS20135 34ae2036392ee418c1f87b8b9cf6c795 174 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 107 121 2.0E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS20135 34ae2036392ee418c1f87b8b9cf6c795 174 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 137 149 2.0E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS20135 34ae2036392ee418c1f87b8b9cf6c795 174 Pfam PF00196 Bacterial regulatory proteins, luxR family 106 159 7.6E-18 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS20135 34ae2036392ee418c1f87b8b9cf6c795 174 Gene3D G3DSA:1.10.10.10 96 170 2.4E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS12040 906425c439cc239919684fd22624a1d6 649 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 25 141 2.4E-19 T 29-03-2018 CDC59_RS12040 906425c439cc239919684fd22624a1d6 649 Gene3D G3DSA:3.30.565.10 5 363 3.3E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS12040 906425c439cc239919684fd22624a1d6 649 SUPERFAMILY SSF55874 10 201 9.58E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS13495 63675dad0f2b14259b7aadbf71c1d443 246 Gene3D G3DSA:3.40.50.2300 1 118 8.7E-32 T 29-03-2018 CDC59_RS13495 63675dad0f2b14259b7aadbf71c1d443 246 SMART SM00448 1 113 1.9E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS13495 63675dad0f2b14259b7aadbf71c1d443 246 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 224 1.4E-16 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDC59_RS13495 63675dad0f2b14259b7aadbf71c1d443 246 Pfam PF00072 Response regulator receiver domain 3 114 1.2E-22 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS13495 63675dad0f2b14259b7aadbf71c1d443 246 SMART SM00862 148 224 2.3E-14 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDC59_RS13495 63675dad0f2b14259b7aadbf71c1d443 246 Gene3D G3DSA:1.10.10.10 119 227 3.7E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS13495 63675dad0f2b14259b7aadbf71c1d443 246 SUPERFAMILY SSF52172 1 178 1.25E-32 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS11380 f26a1758be98a7026a0395698705dd00 511 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 2 464 9.1E-156 T 29-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CDC59_RS11380 f26a1758be98a7026a0395698705dd00 511 Gene3D G3DSA:3.60.20.10 145 246 3.4E-18 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CDC59_RS11380 f26a1758be98a7026a0395698705dd00 511 Gene3D G3DSA:3.60.20.10 6 144 5.5E-31 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CDC59_RS11380 f26a1758be98a7026a0395698705dd00 511 Pfam PF00156 Phosphoribosyl transferase domain 280 393 1.2E-11 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CDC59_RS11380 f26a1758be98a7026a0395698705dd00 511 Gene3D G3DSA:3.40.50.2020 276 444 2.4E-36 T 29-03-2018 CDC59_RS11380 f26a1758be98a7026a0395698705dd00 511 SUPERFAMILY SSF53271 251 482 1.31E-72 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CDC59_RS11380 f26a1758be98a7026a0395698705dd00 511 PIRSF PIRSF000485 1 481 5.5E-157 T 29-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CDC59_RS11380 f26a1758be98a7026a0395698705dd00 511 SUPERFAMILY SSF56235 2 258 4.8E-67 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CDC59_RS11380 f26a1758be98a7026a0395698705dd00 511 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 1 464 45.059 T 29-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CDC59_RS11380 f26a1758be98a7026a0395698705dd00 511 Pfam PF13522 Glutamine amidotransferase domain 64 209 3.7E-16 T 29-03-2018 CDC59_RS09130 a2398b44e0c34f843917ba0ee9bf01be 377 SUPERFAMILY SSF53474 70 296 2.95E-10 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS09130 a2398b44e0c34f843917ba0ee9bf01be 377 Gene3D G3DSA:3.40.50.1820 9 361 2.9E-19 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS13975 895ce276999bdf5a543b18b0e45f717d 614 SMART SM00382 420 593 8.9E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS13975 895ce276999bdf5a543b18b0e45f717d 614 Gene3D G3DSA:3.40.50.300 369 593 4.0E-35 T 29-03-2018 CDC59_RS13975 895ce276999bdf5a543b18b0e45f717d 614 Gene3D G3DSA:1.20.1560.10 27 368 5.6E-45 T 29-03-2018 CDC59_RS13975 895ce276999bdf5a543b18b0e45f717d 614 SUPERFAMILY SSF90123 33 363 3.92E-26 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CDC59_RS13975 895ce276999bdf5a543b18b0e45f717d 614 Pfam PF06472 ABC transporter transmembrane region 2 29 316 2.3E-67 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CDC59_RS13975 895ce276999bdf5a543b18b0e45f717d 614 Pfam PF00005 ABC transporter 414 546 1.6E-15 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS13975 895ce276999bdf5a543b18b0e45f717d 614 ProSitePatterns PS00211 ABC transporters family signature. 518 532 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS13975 895ce276999bdf5a543b18b0e45f717d 614 SUPERFAMILY SSF52540 392 585 1.28E-36 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS10070 6e137903e86fc345f52273023301afd2 422 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 233 416 2.7E-8 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS10070 6e137903e86fc345f52273023301afd2 422 Gene3D G3DSA:1.10.3720.10 29 421 1.1E-41 T 29-03-2018 CDC59_RS10070 6e137903e86fc345f52273023301afd2 422 SUPERFAMILY SSF161098 198 410 3.27E-42 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS05960 05c27c92ad5309936dc9ed94a0382d4b 229 Pfam PF01144 Coenzyme A transferase 9 218 1.0E-66 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CDC59_RS05960 05c27c92ad5309936dc9ed94a0382d4b 229 Gene3D G3DSA:3.40.1080.10 2 229 4.3E-79 T 29-03-2018 CDC59_RS05960 05c27c92ad5309936dc9ed94a0382d4b 229 SUPERFAMILY SSF100950 2 225 1.67E-77 T 29-03-2018 CDC59_RS05960 05c27c92ad5309936dc9ed94a0382d4b 229 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 18 33 - T 29-03-2018 IPR004163 Coenzyme A transferase binding site GO:0008152|GO:0008410 Reactome: R-HSA-77108 CDC59_RS05960 05c27c92ad5309936dc9ed94a0382d4b 229 SMART SM00882 6 219 1.6E-80 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CDC59_RS05960 05c27c92ad5309936dc9ed94a0382d4b 229 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 2 220 1.7E-115 T 29-03-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 CDC59_RS23370 4c9e6d792912c107b8e1f77afbd31257 125 Gene3D G3DSA:2.40.300.10 11 119 4.8E-21 T 29-03-2018 CDC59_RS23370 4c9e6d792912c107b8e1f77afbd31257 125 Pfam PF02924 Bacteriophage lambda head decoration protein D 3 119 7.5E-34 T 29-03-2018 IPR004195 Head decoration protein D GO:0019028 CDC59_RS13895 1e7272deffe1650287d0b00c3ef55289 196 Gene3D G3DSA:1.10.357.10 58 192 5.0E-17 T 29-03-2018 CDC59_RS13895 1e7272deffe1650287d0b00c3ef55289 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 55 8.0E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDC59_RS13895 1e7272deffe1650287d0b00c3ef55289 196 Gene3D G3DSA:1.10.10.60 1 57 8.1E-18 T 29-03-2018 CDC59_RS13895 1e7272deffe1650287d0b00c3ef55289 196 SUPERFAMILY SSF46689 2 69 7.18E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS13895 1e7272deffe1650287d0b00c3ef55289 196 SUPERFAMILY SSF48498 77 191 8.9E-20 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CDC59_RS13895 1e7272deffe1650287d0b00c3ef55289 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 5.4E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDC59_RS13895 1e7272deffe1650287d0b00c3ef55289 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 5.4E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDC59_RS00045 6c88ce48e158c1be0120674cf15643dc 284 Gene3D G3DSA:3.60.21.10 35 256 1.7E-20 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CDC59_RS00045 6c88ce48e158c1be0120674cf15643dc 284 SUPERFAMILY SSF56300 59 279 6.08E-26 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CDC59_RS00045 6c88ce48e158c1be0120674cf15643dc 284 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 60 242 1.1E-6 T 29-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 CDC59_RS16610 8b0ebc8bc04875f63fd6042c2cbdfc5d 304 Pfam PF13469 Sulfotransferase family 6 204 1.1E-16 T 29-03-2018 CDC59_RS16610 8b0ebc8bc04875f63fd6042c2cbdfc5d 304 SUPERFAMILY SSF52540 2 253 2.75E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS16610 8b0ebc8bc04875f63fd6042c2cbdfc5d 304 Gene3D G3DSA:3.40.50.300 2 254 8.2E-24 T 29-03-2018 CDC59_RS01395 8b0ebc8bc04875f63fd6042c2cbdfc5d 304 Pfam PF13469 Sulfotransferase family 6 204 1.1E-16 T 29-03-2018 CDC59_RS01395 8b0ebc8bc04875f63fd6042c2cbdfc5d 304 SUPERFAMILY SSF52540 2 253 2.75E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS01395 8b0ebc8bc04875f63fd6042c2cbdfc5d 304 Gene3D G3DSA:3.40.50.300 2 254 8.2E-24 T 29-03-2018 CDC59_RS10440 4778576ccbe89abc97e83e4e0cb423fe 265 SUPERFAMILY SSF55781 70 255 3.27E-43 T 29-03-2018 IPR029016 GAF domain-like CDC59_RS10440 4778576ccbe89abc97e83e4e0cb423fe 265 Pfam PF01614 Bacterial transcriptional regulator 131 251 8.9E-32 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CDC59_RS10440 4778576ccbe89abc97e83e4e0cb423fe 265 SMART SM00346 13 102 1.9E-20 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CDC59_RS10440 4778576ccbe89abc97e83e4e0cb423fe 265 Gene3D G3DSA:1.10.10.10 1 73 1.2E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS10440 4778576ccbe89abc97e83e4e0cb423fe 265 SUPERFAMILY SSF46785 13 84 1.62E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS10440 4778576ccbe89abc97e83e4e0cb423fe 265 Pfam PF09339 IclR helix-turn-helix domain 16 65 7.1E-14 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CDC59_RS10440 4778576ccbe89abc97e83e4e0cb423fe 265 Gene3D G3DSA:3.30.450.40 78 255 2.0E-44 T 29-03-2018 IPR029016 GAF domain-like CDC59_RS00105 8aaaeeb1151c0b7ab3434a40f7c841e5 622 Pfam PF17297 Phosphoenolpyruvate carboxykinase N-terminal domain 26 245 7.6E-105 T 29-03-2018 IPR035078 Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 CDC59_RS00105 8aaaeeb1151c0b7ab3434a40f7c841e5 622 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 273 281 - T 29-03-2018 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 CDC59_RS00105 8aaaeeb1151c0b7ab3434a40f7c841e5 622 Gene3D G3DSA:3.40.449.10 8 248 8.6E-116 T 29-03-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CDC59_RS00105 8aaaeeb1151c0b7ab3434a40f7c841e5 622 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 14 621 51.272 T 29-03-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 CDC59_RS00105 8aaaeeb1151c0b7ab3434a40f7c841e5 622 SUPERFAMILY SSF53795 249 621 8.93E-152 T 29-03-2018 CDC59_RS00105 8aaaeeb1151c0b7ab3434a40f7c841e5 622 PIRSF PIRSF001348 1 622 2.9E-288 T 29-03-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 CDC59_RS00105 8aaaeeb1151c0b7ab3434a40f7c841e5 622 Gene3D G3DSA:3.90.228.20 249 327 3.5E-20 T 29-03-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CDC59_RS00105 8aaaeeb1151c0b7ab3434a40f7c841e5 622 Gene3D G3DSA:3.90.228.20 334 622 2.3E-122 T 29-03-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CDC59_RS00105 8aaaeeb1151c0b7ab3434a40f7c841e5 622 Pfam PF00821 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain 249 620 5.8E-167 T 29-03-2018 IPR035077 Phosphoenolpyruvate carboxykinase, GTP-utilising, C-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 CDC59_RS00105 8aaaeeb1151c0b7ab3434a40f7c841e5 622 SUPERFAMILY SSF68923 9 248 4.45E-102 T 29-03-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CDC59_RS08305 c96cbe8b4db3542ed799f2dad93053f7 103 SUPERFAMILY SSF50022 1 102 3.54E-30 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CDC59_RS08305 c96cbe8b4db3542ed799f2dad93053f7 103 Gene3D G3DSA:2.102.10.10 1 103 1.9E-24 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CDC59_RS08305 c96cbe8b4db3542ed799f2dad93053f7 103 TIGRFAM TIGR02377 MocE_fam_FeS: Rieske [2Fe-2S] domain protein, MocE subfamily 3 102 4.7E-43 T 29-03-2018 IPR012747 MocE Rieske [2Fe-2S] CDC59_RS08305 c96cbe8b4db3542ed799f2dad93053f7 103 Pfam PF00355 Rieske [2Fe-2S] domain 3 88 8.7E-18 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CDC59_RS11125 0def761432024fe2d84450ca308be951 288 SUPERFAMILY SSF55021 6 85 1.04E-19 T 29-03-2018 CDC59_RS11125 0def761432024fe2d84450ca308be951 288 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 112 139 2.7E-55 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CDC59_RS11125 0def761432024fe2d84450ca308be951 288 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 239 261 2.7E-55 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CDC59_RS11125 0def761432024fe2d84450ca308be951 288 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 40 52 2.7E-55 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CDC59_RS11125 0def761432024fe2d84450ca308be951 288 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 90 112 2.7E-55 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CDC59_RS11125 0def761432024fe2d84450ca308be951 288 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 261 286 2.7E-55 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CDC59_RS11125 0def761432024fe2d84450ca308be951 288 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 8 34 2.7E-55 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CDC59_RS11125 0def761432024fe2d84450ca308be951 288 Pfam PF13740 ACT domain 6 38 3.1E-5 T 29-03-2018 CDC59_RS11125 0def761432024fe2d84450ca308be951 288 PIRSF PIRSF036480 3 288 9.9E-109 T 29-03-2018 CDC59_RS11125 0def761432024fe2d84450ca308be951 288 Gene3D G3DSA:3.30.70.260 1 93 6.7E-28 T 29-03-2018 CDC59_RS11125 0def761432024fe2d84450ca308be951 288 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 7 287 7.1E-101 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CDC59_RS11125 0def761432024fe2d84450ca308be951 288 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 3 287 47.981 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CDC59_RS11125 0def761432024fe2d84450ca308be951 288 SUPERFAMILY SSF53328 90 288 3.92E-61 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CDC59_RS11125 0def761432024fe2d84450ca308be951 288 Pfam PF00551 Formyl transferase 90 269 1.1E-36 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CDC59_RS11125 0def761432024fe2d84450ca308be951 288 Gene3D G3DSA:3.40.50.170 94 288 1.6E-56 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CDC59_RS04755 cbfdabff7ac1d761f551d2ba706a596e 257 Gene3D G3DSA:1.25.40.10 142 256 3.6E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS04755 cbfdabff7ac1d761f551d2ba706a596e 257 Pfam PF16331 TolA binding protein trimerisation 61 124 8.6E-18 T 29-03-2018 IPR032519 YbgF, trimerisation domain GO:0070206 CDC59_RS04755 cbfdabff7ac1d761f551d2ba706a596e 257 TIGRFAM TIGR02795 tol_pal_ybgF: tol-pal system protein YbgF 136 253 1.1E-36 T 29-03-2018 IPR014162 Cell division coordinator CpoB, C-terminal CDC59_RS04755 cbfdabff7ac1d761f551d2ba706a596e 257 Pfam PF13525 Outer membrane lipoprotein 137 254 5.2E-11 T 29-03-2018 CDC59_RS04755 cbfdabff7ac1d761f551d2ba706a596e 257 Hamap MF_02066 Cell division coordinator CpoB [cpoB]. 10 256 19.197 T 29-03-2018 IPR034706 Cell division coordinator CpoB GO:0051301 CDC59_RS04755 cbfdabff7ac1d761f551d2ba706a596e 257 Gene3D G3DSA:1.20.5.50 37 141 6.7E-7 T 29-03-2018 CDC59_RS04755 cbfdabff7ac1d761f551d2ba706a596e 257 SUPERFAMILY SSF48452 140 242 2.23E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS09475 996b93554ac988a42974c63b74c9f434 213 SUPERFAMILY SSF55961 1 144 1.08E-42 T 29-03-2018 CDC59_RS09475 996b93554ac988a42974c63b74c9f434 213 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 6 145 1.5E-47 T 29-03-2018 IPR010419 Carbon monoxide dehydrogenase subunit G CDC59_RS09475 996b93554ac988a42974c63b74c9f434 213 Gene3D G3DSA:3.30.530.20 1 160 4.1E-27 T 29-03-2018 IPR023393 START-like domain CDC59_RS04610 8a60207e06382e81d9417f256d709357 503 Gene3D G3DSA:1.20.5.570 476 501 1.0E-16 T 29-03-2018 CDC59_RS04610 8a60207e06382e81d9417f256d709357 503 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 10 447 1.2E-166 T 29-03-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 CDC59_RS04610 8a60207e06382e81d9417f256d709357 503 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 6 471 4.9E-157 T 29-03-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 CDC59_RS04610 8a60207e06382e81d9417f256d709357 503 SUPERFAMILY SSF50475 3 338 1.18E-113 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CDC59_RS04610 8a60207e06382e81d9417f256d709357 503 Hamap MF_01636 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [ubiD]. 1 503 71.984 T 29-03-2018 IPR023677 UbiD decarboxylyase, bacteria GO:0005886|GO:0006744|GO:0008694 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 CDC59_RS04610 8a60207e06382e81d9417f256d709357 503 Gene3D G3DSA:3.40.1670.10 339 475 2.0E-52 T 29-03-2018 CDC59_RS04610 8a60207e06382e81d9417f256d709357 503 SUPERFAMILY SSF143968 339 501 3.92E-66 T 29-03-2018 CDC59_RS09995 cdc6ff2744adaf9434dfd0c92f9b2253 417 Gene3D G3DSA:3.40.50.2300 17 165 8.1E-10 T 29-03-2018 CDC59_RS09995 cdc6ff2744adaf9434dfd0c92f9b2253 417 Gene3D G3DSA:3.40.50.2300 166 349 2.7E-30 T 29-03-2018 CDC59_RS09995 cdc6ff2744adaf9434dfd0c92f9b2253 417 Pfam PF13458 Periplasmic binding protein 31 381 2.9E-70 T 29-03-2018 IPR028081 Leucine-binding protein domain CDC59_RS09995 cdc6ff2744adaf9434dfd0c92f9b2253 417 SUPERFAMILY SSF53822 30 384 1.88E-70 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CDC59_RS00650 08945f80c23504df36aba33bee60898f 101 SUPERFAMILY SSF55248 1 96 4.84E-36 T 29-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 CDC59_RS00650 08945f80c23504df36aba33bee60898f 101 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 5 93 7.2E-32 T 29-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 CDC59_RS00650 08945f80c23504df36aba33bee60898f 101 Gene3D G3DSA:3.30.1360.20 3 101 8.3E-38 T 29-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 CDC59_RS00650 08945f80c23504df36aba33bee60898f 101 Hamap MF_00434 Putative pterin-4-alpha-carbinolamine dehydratase. 2 95 24.118 T 29-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 CDC59_RS02710 67e80cd6fd92db1463dd1a3c37892841 165 Gene3D G3DSA:2.30.30.220 7 103 2.8E-37 T 29-03-2018 IPR007481 Stringent starvation protein B CDC59_RS02710 67e80cd6fd92db1463dd1a3c37892841 165 PIRSF PIRSF005276 1 165 1.2E-53 T 29-03-2018 IPR007481 Stringent starvation protein B CDC59_RS02710 67e80cd6fd92db1463dd1a3c37892841 165 Pfam PF04386 Stringent starvation protein B 5 165 1.9E-36 T 29-03-2018 IPR007481 Stringent starvation protein B CDC59_RS02710 67e80cd6fd92db1463dd1a3c37892841 165 SUPERFAMILY SSF101738 3 116 5.49E-46 T 29-03-2018 IPR007481 Stringent starvation protein B CDC59_RS08195 e96039fd1f6d8515809d6a7164c7586f 461 TIGRFAM TIGR01933 hflK: HflK protein 123 400 1.2E-88 T 29-03-2018 IPR010201 HflK GO:0016021 CDC59_RS08195 e96039fd1f6d8515809d6a7164c7586f 461 Pfam PF12221 Bacterial membrane protein N terminal 29 83 2.6E-12 T 29-03-2018 IPR020980 Menbrane protein HflK, N-terminal CDC59_RS08195 e96039fd1f6d8515809d6a7164c7586f 461 SMART SM00244 121 298 1.3E-26 T 29-03-2018 IPR001107 Band 7 domain CDC59_RS08195 e96039fd1f6d8515809d6a7164c7586f 461 SUPERFAMILY SSF117892 178 305 2.09E-20 T 29-03-2018 IPR001107 Band 7 domain CDC59_RS08195 e96039fd1f6d8515809d6a7164c7586f 461 Pfam PF01145 SPFH domain / Band 7 family 125 313 1.4E-26 T 29-03-2018 IPR001107 Band 7 domain CDC59_RS09505 d5fa664690efb5132dd2294c11e8d15c 157 PIRSF PIRSF003174 2 157 1.8E-61 T 29-03-2018 IPR010292 Uncharacterised protein family CreA CDC59_RS09505 d5fa664690efb5132dd2294c11e8d15c 157 Pfam PF05981 CreA protein 25 149 2.7E-51 T 29-03-2018 IPR010292 Uncharacterised protein family CreA CDC59_RS18390 71d06f3fb3cbc613c3966a38f028107e 210 SUPERFAMILY SSF52833 4 188 1.89E-33 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS18390 71d06f3fb3cbc613c3966a38f028107e 210 Pfam PF01323 DSBA-like thioredoxin domain 5 185 3.9E-29 T 29-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 CDC59_RS18390 71d06f3fb3cbc613c3966a38f028107e 210 Gene3D G3DSA:3.40.30.10 3 189 1.0E-34 T 29-03-2018 CDC59_RS18390 71d06f3fb3cbc613c3966a38f028107e 210 PIRSF PIRSF006386 1 198 1.2E-35 T 29-03-2018 IPR014440 HCCA isomerase/glutathione S-transferase kappa Reactome: R-HSA-156590 CDC59_RS02650 47b44071793f384deae526d2cbf08532 367 Gene3D G3DSA:3.40.190.10 207 334 2.0E-17 T 29-03-2018 CDC59_RS02650 47b44071793f384deae526d2cbf08532 367 SUPERFAMILY SSF53850 50 345 3.3E-56 T 29-03-2018 CDC59_RS02650 47b44071793f384deae526d2cbf08532 367 Pfam PF13416 Bacterial extracellular solute-binding protein 65 320 2.4E-22 T 29-03-2018 CDC59_RS02650 47b44071793f384deae526d2cbf08532 367 Gene3D G3DSA:3.40.190.10 10 206 7.0E-20 T 29-03-2018 CDC59_RS07515 763494cd2f6b6715cc2828878464b012 157 Pfam PF13577 SnoaL-like domain 9 140 3.1E-13 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CDC59_RS07515 763494cd2f6b6715cc2828878464b012 157 SUPERFAMILY SSF54427 1 157 2.05E-49 T 29-03-2018 IPR032710 NTF2-like domain CDC59_RS07515 763494cd2f6b6715cc2828878464b012 157 Gene3D G3DSA:3.10.450.50 1 156 1.5E-32 T 29-03-2018 CDC59_RS07340 79513e6b3edcf38844898a9e4f97ee3a 365 PIRSF PIRSF005427 13 355 1.5E-112 T 29-03-2018 IPR005588 MucB/RseB CDC59_RS07340 79513e6b3edcf38844898a9e4f97ee3a 365 Pfam PF03888 MucB/RseB N-terminal domain 49 222 9.2E-54 T 29-03-2018 IPR033434 MucB/RseB, N-terminal CDC59_RS07340 79513e6b3edcf38844898a9e4f97ee3a 365 Pfam PF17188 MucB/RseB C-terminal domain 245 348 8.1E-27 T 29-03-2018 IPR033436 MucB/RseB, C-terminal CDC59_RS07340 79513e6b3edcf38844898a9e4f97ee3a 365 Gene3D G3DSA:2.50.20.10 48 220 2.7E-16 T 29-03-2018 CDC59_RS04980 d2ec7a86a7106a5007c767d42008c238 117 Gene3D G3DSA:3.10.50.40 1 117 3.1E-47 T 29-03-2018 CDC59_RS04980 d2ec7a86a7106a5007c767d42008c238 117 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 22 115 1.0E-34 T 29-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain CDC59_RS04980 d2ec7a86a7106a5007c767d42008c238 117 SUPERFAMILY SSF54534 3 117 4.32E-45 T 29-03-2018 CDC59_RS18445 e6eac2a0c54b7b2853ab34358098ba18 246 Gene3D G3DSA:3.40.50.1820 2 244 7.1E-27 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS18445 e6eac2a0c54b7b2853ab34358098ba18 246 Pfam PF12697 Alpha/beta hydrolase family 7 237 2.2E-20 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS18445 e6eac2a0c54b7b2853ab34358098ba18 246 PRINTS PR00111 Alpha/beta hydrolase fold signature 85 98 6.0E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS18445 e6eac2a0c54b7b2853ab34358098ba18 246 PRINTS PR00111 Alpha/beta hydrolase fold signature 71 84 6.0E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS18445 e6eac2a0c54b7b2853ab34358098ba18 246 PRINTS PR00111 Alpha/beta hydrolase fold signature 28 43 6.0E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS18445 e6eac2a0c54b7b2853ab34358098ba18 246 SUPERFAMILY SSF53474 5 244 4.75E-30 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS09090 a8497705e5ac8a7d69764dc7a6546150 275 Gene3D G3DSA:1.10.166.10 4 70 2.1E-30 T 29-03-2018 IPR023180 Tetrahydrodipicolinate-N-succinyltransferase, chain A, domain 1 KEGG: 00300+2.3.1.117 CDC59_RS09090 a8497705e5ac8a7d69764dc7a6546150 275 Pfam PF14805 Tetrahydrodipicolinate N-succinyltransferase N-terminal 4 70 2.0E-27 T 29-03-2018 IPR023180 Tetrahydrodipicolinate-N-succinyltransferase, chain A, domain 1 KEGG: 00300+2.3.1.117 CDC59_RS09090 a8497705e5ac8a7d69764dc7a6546150 275 Gene3D G3DSA:2.160.10.10 89 259 2.4E-35 T 29-03-2018 CDC59_RS09090 a8497705e5ac8a7d69764dc7a6546150 275 TIGRFAM TIGR00965 dapD: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 4 274 5.3E-146 T 29-03-2018 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 CDC59_RS09090 a8497705e5ac8a7d69764dc7a6546150 275 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 117 168 0.001 T 29-03-2018 IPR001451 Hexapeptide repeat CDC59_RS09090 a8497705e5ac8a7d69764dc7a6546150 275 Hamap MF_00811 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 2 274 57.292 T 29-03-2018 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 CDC59_RS09090 a8497705e5ac8a7d69764dc7a6546150 275 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 177 211 1.1E-13 T 29-03-2018 IPR001451 Hexapeptide repeat CDC59_RS09090 a8497705e5ac8a7d69764dc7a6546150 275 SUPERFAMILY SSF51161 4 258 1.66E-75 T 29-03-2018 IPR011004 Trimeric LpxA-like CDC59_RS09090 a8497705e5ac8a7d69764dc7a6546150 275 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 136 164 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CDC59_RS06950 db7c83ac5ee3f14ece597885a2886401 181 Pfam PF02417 Chromate transporter 14 176 5.4E-29 T 29-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 CDC59_RS04065 f4403424eacc5d8b2659bf82a71b9d81 371 Pfam PF00762 Ferrochelatase 16 343 4.6E-113 T 29-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CDC59_RS04065 f4403424eacc5d8b2659bf82a71b9d81 371 Hamap MF_00323 Ferrochelatase [hemH]. 15 344 38.26 T 29-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CDC59_RS04065 f4403424eacc5d8b2659bf82a71b9d81 371 Gene3D G3DSA:3.40.50.1400 13 191 1.4E-48 T 29-03-2018 CDC59_RS04065 f4403424eacc5d8b2659bf82a71b9d81 371 SUPERFAMILY SSF53800 14 351 2.35E-107 T 29-03-2018 CDC59_RS04065 f4403424eacc5d8b2659bf82a71b9d81 371 TIGRFAM TIGR00109 hemH: ferrochelatase 15 344 8.1E-92 T 29-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CDC59_RS04065 f4403424eacc5d8b2659bf82a71b9d81 371 Gene3D G3DSA:3.40.50.1400 192 324 3.0E-37 T 29-03-2018 CDC59_RS04065 f4403424eacc5d8b2659bf82a71b9d81 371 ProSitePatterns PS00534 Ferrochelatase signature. 213 231 - T 29-03-2018 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CDC59_RS17130 ec63c8cb6847fd6c8035d9dc05da855f 273 SUPERFAMILY SSF64518 1 272 1.57E-63 T 29-03-2018 CDC59_RS17130 ec63c8cb6847fd6c8035d9dc05da855f 273 PRINTS PR00207 Flagellin signature 111 134 1.4E-12 T 29-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CDC59_RS17130 ec63c8cb6847fd6c8035d9dc05da855f 273 PRINTS PR00207 Flagellin signature 76 95 1.4E-12 T 29-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CDC59_RS17130 ec63c8cb6847fd6c8035d9dc05da855f 273 PRINTS PR00207 Flagellin signature 37 54 1.4E-12 T 29-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CDC59_RS17130 ec63c8cb6847fd6c8035d9dc05da855f 273 Pfam PF00700 Bacterial flagellin C-terminal helical region 188 271 2.3E-19 T 29-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CDC59_RS17130 ec63c8cb6847fd6c8035d9dc05da855f 273 Pfam PF00669 Bacterial flagellin N-terminal helical region 6 141 2.7E-27 T 29-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CDC59_RS17130 ec63c8cb6847fd6c8035d9dc05da855f 273 Gene3D G3DSA:1.20.1330.10 40 244 1.8E-42 T 29-03-2018 CDC59_RS02345 85f7f2aefbf41293b9049134283d0868 38 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 38 18.009 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS02345 85f7f2aefbf41293b9049134283d0868 38 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 38 1.7E-20 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS02345 85f7f2aefbf41293b9049134283d0868 38 SUPERFAMILY SSF57840 1 38 7.98E-17 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS02345 85f7f2aefbf41293b9049134283d0868 38 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 9 38 7.0E-10 T 29-03-2018 CDC59_RS02345 85f7f2aefbf41293b9049134283d0868 38 Pfam PF00444 Ribosomal protein L36 1 38 2.6E-19 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS02345 85f7f2aefbf41293b9049134283d0868 38 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 37 - T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS15715 8dea65bb57b5e73c822e0a6ea7f75276 450 Gene3D G3DSA:3.90.1150.10 257 443 1.8E-51 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS15715 8dea65bb57b5e73c822e0a6ea7f75276 450 PIRSF PIRSF000521 122 440 1.5E-23 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CDC59_RS15715 8dea65bb57b5e73c822e0a6ea7f75276 450 PIRSF PIRSF000521 19 140 2.0E-9 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CDC59_RS15715 8dea65bb57b5e73c822e0a6ea7f75276 450 Gene3D G3DSA:3.90.1150.10 174 256 4.9E-4 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS15715 8dea65bb57b5e73c822e0a6ea7f75276 450 Gene3D G3DSA:3.90.1150.10 3 173 2.5E-42 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS15715 8dea65bb57b5e73c822e0a6ea7f75276 450 Pfam PF00202 Aminotransferase class-III 21 438 8.9E-101 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CDC59_RS15715 8dea65bb57b5e73c822e0a6ea7f75276 450 SUPERFAMILY SSF53383 16 439 1.09E-125 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS15715 8dea65bb57b5e73c822e0a6ea7f75276 450 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 241 278 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CDC59_RS14220 025fb4b08cb5ff245caa00443ade061b 210 Gene3D G3DSA:2.60.450.10 43 205 2.3E-5 T 29-03-2018 CDC59_RS14220 025fb4b08cb5ff245caa00443ade061b 210 TIGRFAM TIGR04409 LptC_YrbK: LPS export ABC transporter periplasmic protein LptC 20 202 1.0E-48 T 29-03-2018 IPR026265 Lipopolysaccharide export system protein LptC GO:0005887|GO:0015221|GO:0015920 CDC59_RS14220 025fb4b08cb5ff245caa00443ade061b 210 Pfam PF06835 Lipopolysaccharide-assembly, LptC-related 24 203 1.1E-44 T 29-03-2018 IPR010664 Lipopolysaccharide assembly, LptC-related CDC59_RS00925 9eb7901963842f6c8d27a053a550a0aa 364 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 7 356 49.125 T 29-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CDC59_RS00925 9eb7901963842f6c8d27a053a550a0aa 364 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 6 354 1.0E-129 T 29-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CDC59_RS00925 9eb7901963842f6c8d27a053a550a0aa 364 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 23 32 - T 29-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CDC59_RS00925 9eb7901963842f6c8d27a053a550a0aa 364 Gene3D G3DSA:3.20.20.210 2 364 1.9E-99 T 29-03-2018 CDC59_RS00925 9eb7901963842f6c8d27a053a550a0aa 364 SUPERFAMILY SSF51726 4 357 9.24E-108 T 29-03-2018 CDC59_RS00925 9eb7901963842f6c8d27a053a550a0aa 364 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 146 162 - T 29-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CDC59_RS00925 9eb7901963842f6c8d27a053a550a0aa 364 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 10 353 4.9E-122 T 29-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CDC59_RS21055 000a4334e4abfb10d25a5d33aaad2632 466 SUPERFAMILY SSF51905 3 333 2.3E-35 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS21055 000a4334e4abfb10d25a5d33aaad2632 466 Gene3D G3DSA:3.50.50.60 272 367 5.8E-6 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS21055 000a4334e4abfb10d25a5d33aaad2632 466 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 9 322 1.1E-19 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS21055 000a4334e4abfb10d25a5d33aaad2632 466 PIRSF PIRSF037495 1 466 3.4E-138 T 29-03-2018 IPR017224 Opine oxidase, subunit A/hydrogen cyanide synthase, subunit B GO:0016491|GO:0055114 CDC59_RS21055 000a4334e4abfb10d25a5d33aaad2632 466 Gene3D G3DSA:3.50.50.60 129 271 2.7E-9 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS21055 000a4334e4abfb10d25a5d33aaad2632 466 Pfam PF04324 BFD-like [2Fe-2S] binding domain 383 435 5.4E-9 T 29-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain CDC59_RS21055 000a4334e4abfb10d25a5d33aaad2632 466 Gene3D G3DSA:3.40.50.720 3 128 1.5E-17 T 29-03-2018 CDC59_RS21055 000a4334e4abfb10d25a5d33aaad2632 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 9 31 1.6E-7 T 29-03-2018 CDC59_RS21055 000a4334e4abfb10d25a5d33aaad2632 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 304 311 1.6E-7 T 29-03-2018 CDC59_RS21055 000a4334e4abfb10d25a5d33aaad2632 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 156 181 1.6E-7 T 29-03-2018 CDC59_RS21055 000a4334e4abfb10d25a5d33aaad2632 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 112 130 6.3E-10 T 29-03-2018 CDC59_RS21055 000a4334e4abfb10d25a5d33aaad2632 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 6.3E-10 T 29-03-2018 CDC59_RS21055 000a4334e4abfb10d25a5d33aaad2632 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 289 311 6.3E-10 T 29-03-2018 CDC59_RS07225 01fa09ef8f8e4d20759ef4b060c757bd 489 Pfam PF02646 RmuC family 180 471 9.7E-82 T 29-03-2018 IPR003798 DNA recombination RmuC CDC59_RS07225 01fa09ef8f8e4d20759ef4b060c757bd 489 SUPERFAMILY SSF58113 32 188 3.92E-6 T 29-03-2018 CDC59_RS07225 01fa09ef8f8e4d20759ef4b060c757bd 489 Gene3D G3DSA:1.20.5.1230 141 463 4.5E-10 T 29-03-2018 CDC59_RS07225 01fa09ef8f8e4d20759ef4b060c757bd 489 Gene3D G3DSA:1.20.5.1230 38 140 0.36 T 29-03-2018 CDC59_RS20980 6279ce87465aad3d377d4a594ae875e1 1497 Gene3D G3DSA:1.20.5.340 272 856 3.2E-4 T 29-03-2018 CDC59_RS11920 256a3e0d62faf6bbb9a019914b4678de 347 Gene3D G3DSA:3.40.50.2000 157 313 4.8E-25 T 29-03-2018 CDC59_RS11920 256a3e0d62faf6bbb9a019914b4678de 347 Pfam PF13439 Glycosyltransferase Family 4 11 162 2.9E-18 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CDC59_RS11920 256a3e0d62faf6bbb9a019914b4678de 347 SUPERFAMILY SSF53756 2 326 5.76E-58 T 29-03-2018 CDC59_RS11920 256a3e0d62faf6bbb9a019914b4678de 347 Pfam PF13692 Glycosyl transferases group 1 177 291 4.2E-15 T 29-03-2018 CDC59_RS09805 38da6e7ad478b7f339ce1bb73a1e1d2f 346 SUPERFAMILY SSF101790 264 340 5.17E-5 T 29-03-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain CDC59_RS09805 38da6e7ad478b7f339ce1bb73a1e1d2f 346 Gene3D G3DSA:3.30.70.1400 125 259 4.1E-16 T 29-03-2018 CDC59_RS09805 38da6e7ad478b7f339ce1bb73a1e1d2f 346 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 207 271 5.5E-26 T 29-03-2018 IPR017703 YgfZ/GcvT conserved site CDC59_RS09805 38da6e7ad478b7f339ce1bb73a1e1d2f 346 PIRSF PIRSF006487 21 334 2.3E-14 T 29-03-2018 CDC59_RS09805 38da6e7ad478b7f339ce1bb73a1e1d2f 346 Gene3D G3DSA:3.30.70.1400 36 124 9.6E-17 T 29-03-2018 CDC59_RS09805 38da6e7ad478b7f339ce1bb73a1e1d2f 346 Pfam PF01571 Aminomethyltransferase folate-binding domain 34 236 1.3E-13 T 29-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal CDC59_RS09805 38da6e7ad478b7f339ce1bb73a1e1d2f 346 SUPERFAMILY SSF103025 14 262 4.55E-60 T 29-03-2018 CDC59_RS00565 00ac6d3716059468b95be0efba7360f9 586 Gene3D G3DSA:1.10.3720.10 318 585 9.4E-18 T 29-03-2018 CDC59_RS00565 00ac6d3716059468b95be0efba7360f9 586 Gene3D G3DSA:1.10.3720.10 30 280 6.2E-20 T 29-03-2018 CDC59_RS00565 00ac6d3716059468b95be0efba7360f9 586 SUPERFAMILY SSF161098 380 571 2.22E-16 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS00565 00ac6d3716059468b95be0efba7360f9 586 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 401 569 1.7E-11 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS00565 00ac6d3716059468b95be0efba7360f9 586 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 262 1.1E-13 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS00565 00ac6d3716059468b95be0efba7360f9 586 SUPERFAMILY SSF161098 71 266 2.35E-21 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS20130 85e23cd95dc8d1f3c9691dc0d5c88146 315 Pfam PF04773 FecR protein 113 203 7.6E-9 T 29-03-2018 IPR006860 FecR protein CDC59_RS20130 85e23cd95dc8d1f3c9691dc0d5c88146 315 Pfam PF16220 Domain of unknown function (DUF4880) 11 51 4.7E-15 T 29-03-2018 IPR032623 FecR, N-terminal CDC59_RS20130 85e23cd95dc8d1f3c9691dc0d5c88146 315 PIRSF PIRSF018266 1 315 4.2E-58 T 29-03-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component CDC59_RS07660 64b16c90730a7f2646ae88ef6776c825 278 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 5 79 4.5E-20 T 29-03-2018 IPR013589 Bacterial transglutaminase-like, N-terminal CDC59_RS07660 64b16c90730a7f2646ae88ef6776c825 278 Gene3D G3DSA:3.90.260.10 145 258 3.2E-7 T 29-03-2018 IPR002931 Transglutaminase-like CDC59_RS07660 64b16c90730a7f2646ae88ef6776c825 278 SMART SM00460 164 229 3.4E-12 T 29-03-2018 IPR002931 Transglutaminase-like CDC59_RS07660 64b16c90730a7f2646ae88ef6776c825 278 Pfam PF01841 Transglutaminase-like superfamily 132 226 4.1E-18 T 29-03-2018 IPR002931 Transglutaminase-like CDC59_RS07660 64b16c90730a7f2646ae88ef6776c825 278 SUPERFAMILY SSF54001 51 273 1.19E-38 T 29-03-2018 CDC59_RS18475 f7492c4bf25937210016409198846ffb 219 Pfam PF13417 Glutathione S-transferase, N-terminal domain 10 78 1.6E-14 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CDC59_RS18475 f7492c4bf25937210016409198846ffb 219 Pfam PF13410 Glutathione S-transferase, C-terminal domain 128 191 2.1E-7 T 29-03-2018 CDC59_RS18475 f7492c4bf25937210016409198846ffb 219 SUPERFAMILY SSF47616 99 205 3.41E-14 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like CDC59_RS18475 f7492c4bf25937210016409198846ffb 219 SUPERFAMILY SSF52833 9 85 2.04E-16 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS18475 f7492c4bf25937210016409198846ffb 219 Gene3D G3DSA:1.20.1050.10 82 195 1.2E-13 T 29-03-2018 CDC59_RS18475 f7492c4bf25937210016409198846ffb 219 Gene3D G3DSA:3.40.30.10 9 81 1.6E-13 T 29-03-2018 CDC59_RS14380 dcecd657a996660c2b40356cb9ab128f 283 Gene3D G3DSA:1.10.3720.10 32 282 5.8E-27 T 29-03-2018 CDC59_RS14380 dcecd657a996660c2b40356cb9ab128f 283 SUPERFAMILY SSF161098 87 268 4.45E-27 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS14380 dcecd657a996660c2b40356cb9ab128f 283 TIGRFAM TIGR01183 ntrB: nitrate ABC transporter, permease protein 75 269 1.1E-73 T 29-03-2018 IPR005889 Nitrate transport permease GO:0015112|GO:0015706|GO:0016021 CDC59_RS14380 dcecd657a996660c2b40356cb9ab128f 283 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 266 1.2E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS21580 b8ccf13237cc951981b37c648e817dae 141 Gene3D G3DSA:2.20.25.10 4 47 3.1E-18 T 29-03-2018 CDC59_RS21580 b8ccf13237cc951981b37c648e817dae 141 SUPERFAMILY SSF82784 1 140 3.93E-44 T 29-03-2018 IPR003718 OsmC/Ohr family CDC59_RS21580 b8ccf13237cc951981b37c648e817dae 141 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 7 139 5.6E-55 T 29-03-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 CDC59_RS21580 b8ccf13237cc951981b37c648e817dae 141 Pfam PF02566 OsmC-like protein 43 138 1.2E-16 T 29-03-2018 IPR003718 OsmC/Ohr family CDC59_RS21580 b8ccf13237cc951981b37c648e817dae 141 Gene3D G3DSA:3.30.300.20 48 141 8.7E-23 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CDC59_RS16900 ac90f707bb92b60ef9b2d1a219e0c582 158 SUPERFAMILY SSF46955 1 115 3.22E-34 T 29-03-2018 IPR009061 Putative DNA-binding domain CDC59_RS16900 ac90f707bb92b60ef9b2d1a219e0c582 158 Gene3D G3DSA:1.10.1660.10 1 56 2.7E-23 T 29-03-2018 CDC59_RS16900 ac90f707bb92b60ef9b2d1a219e0c582 158 Pfam PF13411 MerR HTH family regulatory protein 1 68 1.1E-18 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CDC59_RS16900 ac90f707bb92b60ef9b2d1a219e0c582 158 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 1.2E-8 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CDC59_RS16900 ac90f707bb92b60ef9b2d1a219e0c582 158 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 1.2E-8 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CDC59_RS16900 ac90f707bb92b60ef9b2d1a219e0c582 158 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 1.2E-8 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CDC59_RS16900 ac90f707bb92b60ef9b2d1a219e0c582 158 Gene3D G3DSA:1.10.1660.10 57 150 9.8E-15 T 29-03-2018 CDC59_RS16900 ac90f707bb92b60ef9b2d1a219e0c582 158 SMART SM00422 1 70 7.8E-27 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CDC59_RS16900 ac90f707bb92b60ef9b2d1a219e0c582 158 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CDC59_RS16900 ac90f707bb92b60ef9b2d1a219e0c582 158 TIGRFAM TIGR02047 CadR-PbrR: Cd(II)/Pb(II)-responsive transcriptional regulator 1 127 6.5E-63 T 29-03-2018 IPR011791 Cd(II)/Pb(II)-responsive transcriptional regulator GO:0003677|GO:0003700|GO:0045893|GO:0046872 CDC59_RS04145 dcd07edbac389db171d428ea475d4d6b 517 SUPERFAMILY SSF81891 231 466 1.57E-55 T 29-03-2018 CDC59_RS04145 dcd07edbac389db171d428ea475d4d6b 517 Pfam PF01743 Poly A polymerase head domain 84 233 5.6E-33 T 29-03-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 CDC59_RS04145 dcd07edbac389db171d428ea475d4d6b 517 Hamap MF_00957 Poly(A) polymerase I [pcnB]. 35 501 36.763 T 29-03-2018 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 CDC59_RS04145 dcd07edbac389db171d428ea475d4d6b 517 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 260 322 1.1E-20 T 29-03-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 CDC59_RS04145 dcd07edbac389db171d428ea475d4d6b 517 Gene3D G3DSA:1.10.3090.10 230 497 3.9E-41 T 29-03-2018 CDC59_RS04145 dcd07edbac389db171d428ea475d4d6b 517 SUPERFAMILY SSF81301 178 230 2.72E-36 T 29-03-2018 CDC59_RS04145 dcd07edbac389db171d428ea475d4d6b 517 SUPERFAMILY SSF81301 57 151 2.72E-36 T 29-03-2018 CDC59_RS04145 dcd07edbac389db171d428ea475d4d6b 517 Pfam PF12626 Polymerase A arginine-rich C-terminus 374 498 1.4E-45 T 29-03-2018 IPR025866 Polymerase A arginine-rich C-terminal domain CDC59_RS04145 dcd07edbac389db171d428ea475d4d6b 517 Gene3D G3DSA:3.30.460.10 54 229 1.2E-48 T 29-03-2018 CDC59_RS04145 dcd07edbac389db171d428ea475d4d6b 517 TIGRFAM TIGR01942 pcnB: poly(A) polymerase 54 499 9.1E-147 T 29-03-2018 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 CDC59_RS11430 65f9470d947bbf25dab0ecd3030ee7eb 969 TIGRFAM TIGR03504 FimV_Cterm: FimV C-terminal domain 925 968 9.4E-20 T 29-03-2018 IPR020011 Motility protein FimV, C-terminal CDC59_RS11430 65f9470d947bbf25dab0ecd3030ee7eb 969 Gene3D G3DSA:3.10.350.10 197 288 9.1E-9 T 29-03-2018 CDC59_RS11430 65f9470d947bbf25dab0ecd3030ee7eb 969 TIGRFAM TIGR03505 FimV_core: FimV N-terminal domain 218 290 1.9E-26 T 29-03-2018 IPR020012 Motility protein FimV, N-terminal CDC59_RS11430 65f9470d947bbf25dab0ecd3030ee7eb 969 Gene3D G3DSA:1.25.40.10 591 969 6.9E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS20840 d09aa3e09b0079f8c19adb8e94c56379 375 Gene3D G3DSA:3.40.50.2000 211 357 1.0E-37 T 29-03-2018 CDC59_RS20840 d09aa3e09b0079f8c19adb8e94c56379 375 SUPERFAMILY SSF53756 1 374 1.12E-137 T 29-03-2018 CDC59_RS20840 d09aa3e09b0079f8c19adb8e94c56379 375 Gene3D G3DSA:3.40.50.2000 1 210 1.9E-76 T 29-03-2018 CDC59_RS20840 d09aa3e09b0079f8c19adb8e94c56379 375 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 3 372 1.1E-156 T 29-03-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 CDC59_RS20840 d09aa3e09b0079f8c19adb8e94c56379 375 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 22 370 1.5E-121 T 29-03-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001 CDC59_RS19215 d7d54e951d777c1b8becf6945ed5f992 338 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 13 321 1.5E-41 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CDC59_RS19215 d7d54e951d777c1b8becf6945ed5f992 338 Hamap MF_00807 1-aminocyclopropane-1-carboxylate deaminase [acdS]. 2 338 72.012 T 29-03-2018 IPR020601 1-aminocyclopropane-1-carboxylate deaminase, bacterial GO:0008660|GO:0009310|GO:0030170 KEGG: 00270+3.5.99.7 CDC59_RS19215 d7d54e951d777c1b8becf6945ed5f992 338 SUPERFAMILY SSF53686 5 332 3.02E-99 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CDC59_RS19215 d7d54e951d777c1b8becf6945ed5f992 338 Gene3D G3DSA:3.40.50.1100 153 338 1.6E-26 T 29-03-2018 CDC59_RS19215 d7d54e951d777c1b8becf6945ed5f992 338 PIRSF PIRSF006278 1 338 6.8E-124 T 29-03-2018 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase CDC59_RS19215 d7d54e951d777c1b8becf6945ed5f992 338 Gene3D G3DSA:3.40.50.1100 50 152 4.3E-28 T 29-03-2018 CDC59_RS19215 d7d54e951d777c1b8becf6945ed5f992 338 TIGRFAM TIGR01274 ACC_deam: 1-aminocyclopropane-1-carboxylate deaminase 2 337 1.1E-194 T 29-03-2018 IPR005965 1-aminocyclopropane-1-carboxylate deaminase GO:0008660|GO:0009310|GO:0030170 KEGG: 00270+3.5.99.7 CDC59_RS08005 7d96ccad23d30472bdf3d0de571e919b 222 SUPERFAMILY SSF52172 2 123 2.28E-11 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS08005 7d96ccad23d30472bdf3d0de571e919b 222 Gene3D G3DSA:3.40.50.2300 1 118 4.8E-10 T 29-03-2018 CDC59_RS08005 7d96ccad23d30472bdf3d0de571e919b 222 SMART SM00421 154 211 4.6E-17 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS08005 7d96ccad23d30472bdf3d0de571e919b 222 SUPERFAMILY SSF46894 147 215 2.28E-17 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CDC59_RS08005 7d96ccad23d30472bdf3d0de571e919b 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 171 2.4E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS08005 7d96ccad23d30472bdf3d0de571e919b 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 187 199 2.4E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS08005 7d96ccad23d30472bdf3d0de571e919b 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 187 2.4E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS08005 7d96ccad23d30472bdf3d0de571e919b 222 Gene3D G3DSA:1.10.10.10 119 218 5.4E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS08005 7d96ccad23d30472bdf3d0de571e919b 222 Pfam PF00072 Response regulator receiver domain 5 111 6.7E-7 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS08005 7d96ccad23d30472bdf3d0de571e919b 222 Pfam PF00196 Bacterial regulatory proteins, luxR family 158 211 6.5E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS23800 28072bd2e290a26667d6b1cb86e735a4 112 Pfam PF11604 Copper binding periplasmic protein CusF 46 110 1.7E-22 T 29-03-2018 IPR021647 Copper binding periplasmic protein CusF CDC59_RS22595 f0620237e9ef105a47a317bb069cefb7 536 SUPERFAMILY SSF56425 232 347 6.13E-39 T 29-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CDC59_RS22595 f0620237e9ef105a47a317bb069cefb7 536 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 17 36 5.2E-5 T 29-03-2018 CDC59_RS22595 f0620237e9ef105a47a317bb069cefb7 536 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 349 371 5.2E-5 T 29-03-2018 CDC59_RS22595 f0620237e9ef105a47a317bb069cefb7 536 SUPERFAMILY SSF51905 13 258 1.17E-59 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS22595 f0620237e9ef105a47a317bb069cefb7 536 SUPERFAMILY SSF51905 350 419 1.17E-59 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS22595 f0620237e9ef105a47a317bb069cefb7 536 Gene3D G3DSA:1.20.58.100 408 505 2.1E-15 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CDC59_RS22595 f0620237e9ef105a47a317bb069cefb7 536 Gene3D G3DSA:3.50.50.60 307 402 2.1E-14 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS22595 f0620237e9ef105a47a317bb069cefb7 536 SUPERFAMILY SSF46977 426 508 1.31E-18 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CDC59_RS22595 f0620237e9ef105a47a317bb069cefb7 536 Gene3D G3DSA:3.50.50.60 5 291 2.5E-41 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS22595 f0620237e9ef105a47a317bb069cefb7 536 Pfam PF02910 Fumarate reductase flavoprotein C-term 429 506 1.4E-9 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CDC59_RS22595 f0620237e9ef105a47a317bb069cefb7 536 Pfam PF00890 FAD binding domain 16 386 1.8E-83 T 29-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CDC59_RS22595 f0620237e9ef105a47a317bb069cefb7 536 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 14 502 6.7E-154 T 29-03-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 CDC59_RS04225 76f4c6085393d1ececfc617acf74b2f8 221 Gene3D G3DSA:1.10.760.10 21 123 4.4E-4 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS04225 76f4c6085393d1ececfc617acf74b2f8 221 Pfam PF11769 Protein of unknown function (DUF3313) 20 215 5.7E-50 T 29-03-2018 IPR021747 Protein of unknown function DUF3313 CDC59_RS21620 113882f67cbebdf8181abee01991b304 508 Gene3D G3DSA:1.20.1600.10 31 497 7.7E-101 T 29-03-2018 CDC59_RS21620 113882f67cbebdf8181abee01991b304 508 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 23 494 2.8E-118 T 29-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 CDC59_RS21620 113882f67cbebdf8181abee01991b304 508 SUPERFAMILY SSF56954 16 45 2.22E-111 T 29-03-2018 CDC59_RS21620 113882f67cbebdf8181abee01991b304 508 SUPERFAMILY SSF56954 80 497 2.22E-111 T 29-03-2018 CDC59_RS21620 113882f67cbebdf8181abee01991b304 508 Pfam PF02321 Outer membrane efflux protein 89 281 6.2E-24 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CDC59_RS21620 113882f67cbebdf8181abee01991b304 508 Pfam PF02321 Outer membrane efflux protein 307 491 8.7E-32 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CDC59_RS11120 e034caa3b97db92700f9194a80482148 242 TIGRFAM TIGR01406 dnaQ_proteo: DNA polymerase III, epsilon subunit 2 231 1.4E-86 T 29-03-2018 IPR006309 DNA polymerase 3, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDC59_RS11120 e034caa3b97db92700f9194a80482148 242 Pfam PF00929 Exonuclease 4 165 4.2E-36 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CDC59_RS11120 e034caa3b97db92700f9194a80482148 242 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 4 195 1.1E-59 T 29-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDC59_RS11120 e034caa3b97db92700f9194a80482148 242 SUPERFAMILY SSF53098 1 175 1.56E-56 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDC59_RS11120 e034caa3b97db92700f9194a80482148 242 SMART SM00479 2 174 2.4E-51 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CDC59_RS11120 e034caa3b97db92700f9194a80482148 242 Gene3D G3DSA:3.30.420.10 2 176 2.1E-41 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDC59_RS00080 4c6a2525b70ea64c220ef1cf47877062 297 Pfam PF01734 Patatin-like phospholipase 9 213 2.6E-23 T 29-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 CDC59_RS00080 4c6a2525b70ea64c220ef1cf47877062 297 Gene3D G3DSA:3.40.1090.10 8 219 2.6E-15 T 29-03-2018 CDC59_RS00080 4c6a2525b70ea64c220ef1cf47877062 297 SUPERFAMILY SSF52151 10 261 7.06E-26 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CDC59_RS19875 2de0e9b63600842f13c0d035fe7ca9f5 116 Pfam PF00037 4Fe-4S binding domain 34 56 1.5E-7 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CDC59_RS19875 2de0e9b63600842f13c0d035fe7ca9f5 116 Pfam PF11953 Domain of unknown function (DUF3470) 66 107 1.0E-12 T 29-03-2018 IPR022569 Ferredoxin, C-terminal CDC59_RS19875 2de0e9b63600842f13c0d035fe7ca9f5 116 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CDC59_RS19875 2de0e9b63600842f13c0d035fe7ca9f5 116 SUPERFAMILY SSF54862 2 99 6.58E-23 T 29-03-2018 CDC59_RS19875 2de0e9b63600842f13c0d035fe7ca9f5 116 Gene3D G3DSA:3.30.70.20 2 17 0.15 T 29-03-2018 CDC59_RS19875 2de0e9b63600842f13c0d035fe7ca9f5 116 Gene3D G3DSA:3.30.70.20 46 107 2.2E-8 T 29-03-2018 CDC59_RS19875 2de0e9b63600842f13c0d035fe7ca9f5 116 Gene3D G3DSA:3.30.70.20 18 45 2.8E-10 T 29-03-2018 CDC59_RS19875 2de0e9b63600842f13c0d035fe7ca9f5 116 PRINTS PR00354 7Fe ferredoxin signature 35 52 1.7E-13 T 29-03-2018 IPR000813 7Fe ferredoxin GO:0009055 CDC59_RS19875 2de0e9b63600842f13c0d035fe7ca9f5 116 PRINTS PR00354 7Fe ferredoxin signature 9 19 1.7E-13 T 29-03-2018 IPR000813 7Fe ferredoxin GO:0009055 CDC59_RS19875 2de0e9b63600842f13c0d035fe7ca9f5 116 PRINTS PR00354 7Fe ferredoxin signature 19 29 1.7E-13 T 29-03-2018 IPR000813 7Fe ferredoxin GO:0009055 CDC59_RS02130 322283e2ab089ba7bd957926342763cd 126 Hamap MF_00422 Protein translocase subunit SecE [secE]. 65 120 11.378 T 29-03-2018 IPR022943 Preprotein translocase subunit SecE Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CDC59_RS02130 322283e2ab089ba7bd957926342763cd 126 Gene3D G3DSA:1.20.5.1030 67 118 1.1E-18 T 29-03-2018 CDC59_RS02130 322283e2ab089ba7bd957926342763cd 126 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 68 122 1.3E-18 T 29-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 CDC59_RS02130 322283e2ab089ba7bd957926342763cd 126 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 69 119 2.6E-19 T 29-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CDC59_RS02130 322283e2ab089ba7bd957926342763cd 126 PRINTS PR01650 Bacterial translocase SecE signature 88 108 1.3E-12 T 29-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 CDC59_RS02130 322283e2ab089ba7bd957926342763cd 126 PRINTS PR01650 Bacterial translocase SecE signature 64 84 1.3E-12 T 29-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 CDC59_RS02130 322283e2ab089ba7bd957926342763cd 126 PRINTS PR01650 Bacterial translocase SecE signature 43 64 1.3E-12 T 29-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 CDC59_RS22055 b63e6b872e31839a0ea6d2e18534ba2d 514 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 327 482 6.5E-52 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CDC59_RS22055 b63e6b872e31839a0ea6d2e18534ba2d 514 Gene3D G3DSA:3.40.50.10600 11 131 1.1E-26 T 29-03-2018 CDC59_RS22055 b63e6b872e31839a0ea6d2e18534ba2d 514 SMART SM00283 267 514 3.5E-86 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CDC59_RS22055 b63e6b872e31839a0ea6d2e18534ba2d 514 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 20 114 2.2E-12 T 29-03-2018 IPR000014 PAS domain CDC59_RS22055 b63e6b872e31839a0ea6d2e18534ba2d 514 Pfam PF08447 PAS fold 31 114 1.1E-16 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 CDC59_RS22055 b63e6b872e31839a0ea6d2e18534ba2d 514 SUPERFAMILY SSF55785 21 114 1.73E-25 T 29-03-2018 IPR000014 PAS domain CDC59_RS22055 b63e6b872e31839a0ea6d2e18534ba2d 514 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 365 392 2.8E-48 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS22055 b63e6b872e31839a0ea6d2e18534ba2d 514 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 394 423 2.8E-48 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS22055 b63e6b872e31839a0ea6d2e18534ba2d 514 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 442 471 2.8E-48 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS22055 b63e6b872e31839a0ea6d2e18534ba2d 514 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 288 317 2.8E-48 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS22055 b63e6b872e31839a0ea6d2e18534ba2d 514 Gene3D G3DSA:1.10.287.950 322 514 4.9E-45 T 29-03-2018 CDC59_RS22055 b63e6b872e31839a0ea6d2e18534ba2d 514 Gene3D G3DSA:1.10.287.950 182 321 2.4E-9 T 29-03-2018 CDC59_RS22055 b63e6b872e31839a0ea6d2e18534ba2d 514 SMART SM00086 80 121 0.0023 T 29-03-2018 IPR001610 PAC motif CDC59_RS22055 b63e6b872e31839a0ea6d2e18534ba2d 514 SUPERFAMILY SSF58104 240 514 5.1E-65 T 29-03-2018 CDC59_RS06930 d3c46e559c1fd7dfeaa6f6e7f0d039af 661 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 587 651 7.3E-24 T 29-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 CDC59_RS06930 d3c46e559c1fd7dfeaa6f6e7f0d039af 661 Pfam PF00204 DNA gyrase B 267 403 1.0E-33 T 29-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDC59_RS06930 d3c46e559c1fd7dfeaa6f6e7f0d039af 661 ProSitePatterns PS00177 DNA topoisomerase II signature. 434 442 - T 29-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDC59_RS06930 d3c46e559c1fd7dfeaa6f6e7f0d039af 661 Gene3D G3DSA:3.40.50.670 413 659 6.0E-77 T 29-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDC59_RS06930 d3c46e559c1fd7dfeaa6f6e7f0d039af 661 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 35 177 1.8E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS06930 d3c46e559c1fd7dfeaa6f6e7f0d039af 661 SMART SM00387 29 179 1.2E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS06930 d3c46e559c1fd7dfeaa6f6e7f0d039af 661 PRINTS PR00418 DNA topoisomerase II family signature 114 128 2.3E-58 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDC59_RS06930 d3c46e559c1fd7dfeaa6f6e7f0d039af 661 PRINTS PR00418 DNA topoisomerase II family signature 519 536 2.3E-58 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDC59_RS06930 d3c46e559c1fd7dfeaa6f6e7f0d039af 661 PRINTS PR00418 DNA topoisomerase II family signature 284 297 2.3E-58 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDC59_RS06930 d3c46e559c1fd7dfeaa6f6e7f0d039af 661 PRINTS PR00418 DNA topoisomerase II family signature 501 517 2.3E-58 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDC59_RS06930 d3c46e559c1fd7dfeaa6f6e7f0d039af 661 PRINTS PR00418 DNA topoisomerase II family signature 539 551 2.3E-58 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDC59_RS06930 d3c46e559c1fd7dfeaa6f6e7f0d039af 661 PRINTS PR00418 DNA topoisomerase II family signature 591 607 2.3E-58 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDC59_RS06930 d3c46e559c1fd7dfeaa6f6e7f0d039af 661 PRINTS PR00418 DNA topoisomerase II family signature 33 48 2.3E-58 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDC59_RS06930 d3c46e559c1fd7dfeaa6f6e7f0d039af 661 PRINTS PR00418 DNA topoisomerase II family signature 68 81 2.3E-58 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDC59_RS06930 d3c46e559c1fd7dfeaa6f6e7f0d039af 661 PRINTS PR00418 DNA topoisomerase II family signature 432 446 2.3E-58 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDC59_RS06930 d3c46e559c1fd7dfeaa6f6e7f0d039af 661 Gene3D G3DSA:3.30.565.10 19 222 6.1E-57 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS06930 d3c46e559c1fd7dfeaa6f6e7f0d039af 661 SMART SM00433 35 655 5.5E-186 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CDC59_RS06930 d3c46e559c1fd7dfeaa6f6e7f0d039af 661 SUPERFAMILY SSF56719 406 652 1.36E-74 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CDC59_RS06930 d3c46e559c1fd7dfeaa6f6e7f0d039af 661 SUPERFAMILY SSF55874 7 221 3.01E-55 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS06930 d3c46e559c1fd7dfeaa6f6e7f0d039af 661 Gene3D G3DSA:3.30.230.10 223 409 7.8E-32 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CDC59_RS06930 d3c46e559c1fd7dfeaa6f6e7f0d039af 661 SUPERFAMILY SSF54211 260 405 3.41E-36 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CDC59_RS06930 d3c46e559c1fd7dfeaa6f6e7f0d039af 661 Pfam PF01751 Toprim domain 431 537 2.9E-12 T 29-03-2018 IPR006171 TOPRIM domain CDC59_RS06930 d3c46e559c1fd7dfeaa6f6e7f0d039af 661 Hamap MF_00938 DNA topoisomerase 4 subunit B [parE]. 4 659 43.974 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CDC59_RS06930 d3c46e559c1fd7dfeaa6f6e7f0d039af 661 PRINTS PR01098 Topoisomerase IV subunit B signature 380 405 3.8E-29 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CDC59_RS06930 d3c46e559c1fd7dfeaa6f6e7f0d039af 661 PRINTS PR01098 Topoisomerase IV subunit B signature 329 344 3.8E-29 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CDC59_RS06930 d3c46e559c1fd7dfeaa6f6e7f0d039af 661 PRINTS PR01098 Topoisomerase IV subunit B signature 140 154 3.8E-29 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CDC59_RS06930 d3c46e559c1fd7dfeaa6f6e7f0d039af 661 PRINTS PR01098 Topoisomerase IV subunit B signature 356 379 3.8E-29 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CDC59_RS06930 d3c46e559c1fd7dfeaa6f6e7f0d039af 661 PRINTS PR01098 Topoisomerase IV subunit B signature 466 487 3.8E-29 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CDC59_RS06930 d3c46e559c1fd7dfeaa6f6e7f0d039af 661 PRINTS PR01098 Topoisomerase IV subunit B signature 28 41 3.8E-29 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CDC59_RS06930 d3c46e559c1fd7dfeaa6f6e7f0d039af 661 PRINTS PR01098 Topoisomerase IV subunit B signature 312 328 3.8E-29 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CDC59_RS05445 63fc82d290ae87b9ccd9b0a395d818aa 219 PRINTS PR01021 OMPA domain signature 149 165 7.9E-20 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CDC59_RS05445 63fc82d290ae87b9ccd9b0a395d818aa 219 PRINTS PR01021 OMPA domain signature 104 126 7.9E-20 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CDC59_RS05445 63fc82d290ae87b9ccd9b0a395d818aa 219 PRINTS PR01021 OMPA domain signature 134 149 7.9E-20 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CDC59_RS05445 63fc82d290ae87b9ccd9b0a395d818aa 219 Pfam PF00691 OmpA family 103 187 9.6E-19 T 29-03-2018 IPR006665 OmpA-like domain CDC59_RS05445 63fc82d290ae87b9ccd9b0a395d818aa 219 PRINTS PR01022 Outer membrane protein A signature 191 204 4.0E-5 T 29-03-2018 IPR002368 Outer membrane protein, OmpA GO:0005198|GO:0009279|GO:0016021 CDC59_RS05445 63fc82d290ae87b9ccd9b0a395d818aa 219 PRINTS PR01022 Outer membrane protein A signature 158 177 4.0E-5 T 29-03-2018 IPR002368 Outer membrane protein, OmpA GO:0005198|GO:0009279|GO:0016021 CDC59_RS05445 63fc82d290ae87b9ccd9b0a395d818aa 219 PRINTS PR01022 Outer membrane protein A signature 92 107 4.0E-5 T 29-03-2018 IPR002368 Outer membrane protein, OmpA GO:0005198|GO:0009279|GO:0016021 CDC59_RS05445 63fc82d290ae87b9ccd9b0a395d818aa 219 Gene3D G3DSA:3.30.1330.60 76 219 1.1E-35 T 29-03-2018 IPR006665 OmpA-like domain CDC59_RS05445 63fc82d290ae87b9ccd9b0a395d818aa 219 SUPERFAMILY SSF103088 91 212 8.37E-33 T 29-03-2018 IPR006665 OmpA-like domain CDC59_RS12215 ffa1a1ebba153f9558f49dcad78e2cf7 384 Pfam PF01292 Prokaryotic cytochrome b561 158 338 4.3E-16 T 29-03-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 CDC59_RS12215 ffa1a1ebba153f9558f49dcad78e2cf7 384 SUPERFAMILY SSF81342 152 368 1.1E-41 T 29-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 CDC59_RS12215 ffa1a1ebba153f9558f49dcad78e2cf7 384 Gene3D G3DSA:1.20.950.20 150 371 7.9E-39 T 29-03-2018 CDC59_RS12215 ffa1a1ebba153f9558f49dcad78e2cf7 384 TIGRFAM TIGR01583 formate-DH-gamm: formate dehydrogenase, gamma subunit 155 359 2.2E-48 T 29-03-2018 IPR006471 Formate dehydrogenase, gamma subunit GO:0008863|GO:0009326|GO:0016021|GO:0045333 CDC59_RS12350 435c622a2bd186152ba6c03881e15293 68 Gene3D G3DSA:3.40.50.300 13 68 1.5E-7 T 29-03-2018 CDC59_RS12350 435c622a2bd186152ba6c03881e15293 68 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 24 67 3.5E-7 T 29-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 CDC59_RS03435 21721380b394070631135a64fd945743 174 SUPERFAMILY SSF52833 9 172 2.25E-34 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS03435 21721380b394070631135a64fd945743 174 ProSitePatterns PS00194 Thioredoxin family active site. 66 84 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CDC59_RS03435 21721380b394070631135a64fd945743 174 Gene3D G3DSA:3.40.30.10 24 174 9.5E-30 T 29-03-2018 CDC59_RS03435 21721380b394070631135a64fd945743 174 Pfam PF08534 Redoxin 46 163 5.7E-21 T 29-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 CDC59_RS14510 338a61772233df0604191799f7c11e0c 248 SUPERFAMILY SSF53254 1 245 7.79E-78 T 29-03-2018 IPR029033 Histidine phosphatase superfamily CDC59_RS14510 338a61772233df0604191799f7c11e0c 248 Gene3D G3DSA:3.40.50.1240 1 248 1.4E-65 T 29-03-2018 IPR029033 Histidine phosphatase superfamily CDC59_RS14510 338a61772233df0604191799f7c11e0c 248 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 2 246 1.0E-113 T 29-03-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 CDC59_RS14510 338a61772233df0604191799f7c11e0c 248 PIRSF PIRSF000709 143 238 0.12 T 29-03-2018 CDC59_RS14510 338a61772233df0604191799f7c11e0c 248 PIRSF PIRSF000709 2 110 2.3E-6 T 29-03-2018 CDC59_RS14510 338a61772233df0604191799f7c11e0c 248 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 1 228 44.884 T 29-03-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 CDC59_RS14510 338a61772233df0604191799f7c11e0c 248 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 127 1.2E-28 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CDC59_RS14510 338a61772233df0604191799f7c11e0c 248 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 144 218 7.8E-5 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CDC59_RS14510 338a61772233df0604191799f7c11e0c 248 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 6 15 - T 29-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 CDC59_RS14510 338a61772233df0604191799f7c11e0c 248 SMART SM00855 3 189 1.4E-27 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CDC59_RS03970 017d2c3bbdc4a324e77736a8807ff74d 298 SUPERFAMILY SSF82689 181 276 7.98E-19 T 29-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 CDC59_RS03970 017d2c3bbdc4a324e77736a8807ff74d 298 Gene3D G3DSA:2.30.30.60 129 178 5.1E-14 T 29-03-2018 CDC59_RS03970 017d2c3bbdc4a324e77736a8807ff74d 298 SUPERFAMILY SSF82861 28 111 4.71E-15 T 29-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 CDC59_RS03970 017d2c3bbdc4a324e77736a8807ff74d 298 Gene3D G3DSA:3.30.70.100 179 273 1.5E-10 T 29-03-2018 CDC59_RS03970 017d2c3bbdc4a324e77736a8807ff74d 298 Pfam PF00924 Mechanosensitive ion channel 72 265 4.3E-37 T 29-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 CDC59_RS03970 017d2c3bbdc4a324e77736a8807ff74d 298 SUPERFAMILY SSF50182 114 179 1.96E-16 T 29-03-2018 IPR010920 LSM domain CDC59_RS02625 04196e457ad6049c5c35132503be8565 85 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 3 47 8.0E-23 T 29-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 CDC59_RS02625 04196e457ad6049c5c35132503be8565 85 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 84 23.753 T 29-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 CDC59_RS02625 04196e457ad6049c5c35132503be8565 85 Pfam PF02416 mttA/Hcf106 family 5 49 2.5E-14 T 29-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 CDC59_RS19400 089233bd6f31178efd6bb9f19246e687 385 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 341 360 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CDC59_RS19400 089233bd6f31178efd6bb9f19246e687 385 Gene3D G3DSA:1.10.540.10 3 119 4.0E-24 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CDC59_RS19400 089233bd6f31178efd6bb9f19246e687 385 Gene3D G3DSA:1.20.140.10 215 385 4.9E-56 T 29-03-2018 CDC59_RS19400 089233bd6f31178efd6bb9f19246e687 385 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 123 135 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CDC59_RS19400 089233bd6f31178efd6bb9f19246e687 385 SUPERFAMILY SSF56645 6 241 4.97E-72 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CDC59_RS19400 089233bd6f31178efd6bb9f19246e687 385 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 11 117 2.6E-23 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CDC59_RS19400 089233bd6f31178efd6bb9f19246e687 385 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 215 4.9E-30 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CDC59_RS19400 089233bd6f31178efd6bb9f19246e687 385 SUPERFAMILY SSF47203 228 384 5.32E-51 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CDC59_RS19400 089233bd6f31178efd6bb9f19246e687 385 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 228 383 1.7E-43 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CDC59_RS19400 089233bd6f31178efd6bb9f19246e687 385 Gene3D G3DSA:2.40.110.10 120 214 1.0E-39 T 29-03-2018 CDC59_RS19400 089233bd6f31178efd6bb9f19246e687 385 PIRSF PIRSF016578 12 90 5.4E-4 T 29-03-2018 CDC59_RS19400 089233bd6f31178efd6bb9f19246e687 385 PIRSF PIRSF016578 101 377 2.6E-15 T 29-03-2018 CDC59_RS00135 21a9008ea9b94991eb83b5f04c26e2a7 686 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 463 591 9.2E-35 T 29-03-2018 IPR025299 CstA, C-terminal domain CDC59_RS00135 21a9008ea9b94991eb83b5f04c26e2a7 686 Pfam PF02554 Carbon starvation protein CstA 32 408 5.6E-170 T 29-03-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 CDC59_RS02550 df87d428d5e9ef6dd8457dc7ccaae186 318 SMART SM00382 28 217 2.0E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS02550 df87d428d5e9ef6dd8457dc7ccaae186 318 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS02550 df87d428d5e9ef6dd8457dc7ccaae186 318 Pfam PF00005 ABC transporter 19 161 2.2E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS02550 df87d428d5e9ef6dd8457dc7ccaae186 318 Gene3D G3DSA:3.40.50.300 1 250 6.1E-64 T 29-03-2018 CDC59_RS02550 df87d428d5e9ef6dd8457dc7ccaae186 318 SUPERFAMILY SSF52540 3 225 3.18E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS06805 ed9218b2850256264291f36c29e707c4 348 SUPERFAMILY SSF53335 99 233 3.09E-10 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS06805 ed9218b2850256264291f36c29e707c4 348 SUPERFAMILY SSF53335 281 335 3.09E-10 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS06805 ed9218b2850256264291f36c29e707c4 348 Gene3D G3DSA:3.40.50.150 33 345 1.3E-16 T 29-03-2018 CDC59_RS06805 ed9218b2850256264291f36c29e707c4 348 Pfam PF10017 Histidine-specific methyltransferase, SAM-dependent 47 343 4.2E-98 T 29-03-2018 IPR019257 Histidine-specific methyltransferase, SAM-dependent CDC59_RS06805 ed9218b2850256264291f36c29e707c4 348 TIGRFAM TIGR03438 egtD_ergothio: dimethylhistidine N-methyltransferase 46 343 9.0E-116 T 29-03-2018 IPR035094 Histidine N-alpha-methyltransferase KEGG: 00340+2.1.1.44|MetaCyc: PWY-7255|MetaCyc: PWY-7550 CDC59_RS06805 ed9218b2850256264291f36c29e707c4 348 PIRSF PIRSF018005 10 347 3.2E-142 T 29-03-2018 IPR017804 Methyltransferase EgtD-like CDC59_RS00500 2a500b8f2c92f8663b3dee83b441b3b7 215 SMART SM00448 5 121 2.5E-9 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS00500 2a500b8f2c92f8663b3dee83b441b3b7 215 Gene3D G3DSA:3.40.50.2300 5 139 5.4E-19 T 29-03-2018 CDC59_RS00500 2a500b8f2c92f8663b3dee83b441b3b7 215 SMART SM00421 149 206 4.3E-16 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS00500 2a500b8f2c92f8663b3dee83b441b3b7 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 1.0E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS00500 2a500b8f2c92f8663b3dee83b441b3b7 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 1.0E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS00500 2a500b8f2c92f8663b3dee83b441b3b7 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 1.0E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS00500 2a500b8f2c92f8663b3dee83b441b3b7 215 SUPERFAMILY SSF52172 6 134 4.13E-19 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS00500 2a500b8f2c92f8663b3dee83b441b3b7 215 Pfam PF00072 Response regulator receiver domain 7 115 3.2E-16 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS00500 2a500b8f2c92f8663b3dee83b441b3b7 215 Gene3D G3DSA:1.10.10.10 144 212 1.1E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS00500 2a500b8f2c92f8663b3dee83b441b3b7 215 SUPERFAMILY SSF46894 141 211 1.63E-17 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CDC59_RS00500 2a500b8f2c92f8663b3dee83b441b3b7 215 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 206 1.7E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS23535 7718bec83fc8b2656f878cbd10108c09 251 Gene3D G3DSA:1.20.120.330 26 176 1.3E-10 T 29-03-2018 CDC59_RS13155 f32cf14ead8646f6f85c683cf3c27282 213 Gene3D G3DSA:1.20.1050.10 79 212 2.6E-17 T 29-03-2018 CDC59_RS13155 f32cf14ead8646f6f85c683cf3c27282 213 SUPERFAMILY SSF47616 86 199 3.06E-20 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like CDC59_RS13155 f32cf14ead8646f6f85c683cf3c27282 213 SUPERFAMILY SSF52833 6 88 9.24E-22 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS13155 f32cf14ead8646f6f85c683cf3c27282 213 Pfam PF02798 Glutathione S-transferase, N-terminal domain 7 78 2.6E-13 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CDC59_RS13155 f32cf14ead8646f6f85c683cf3c27282 213 Gene3D G3DSA:3.40.30.10 1 78 3.0E-21 T 29-03-2018 CDC59_RS13155 f32cf14ead8646f6f85c683cf3c27282 213 Pfam PF13410 Glutathione S-transferase, C-terminal domain 133 187 1.2E-7 T 29-03-2018 CDC59_RS17530 a52a1183627af3577a68aa8636d6093c 413 Gene3D G3DSA:1.20.1250.20 11 207 4.3E-28 T 29-03-2018 CDC59_RS17530 a52a1183627af3577a68aa8636d6093c 413 Gene3D G3DSA:1.20.1250.20 214 407 2.1E-17 T 29-03-2018 CDC59_RS17530 a52a1183627af3577a68aa8636d6093c 413 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 16 393 5.3E-91 T 29-03-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 CDC59_RS17530 a52a1183627af3577a68aa8636d6093c 413 Pfam PF07690 Major Facilitator Superfamily 25 364 8.5E-42 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDC59_RS17530 a52a1183627af3577a68aa8636d6093c 413 SUPERFAMILY SSF103473 9 404 2.49E-63 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS10775 86ebb58de5ef32e2aea22cdd09c1d2ae 635 Pfam PF07690 Major Facilitator Superfamily 19 328 1.3E-11 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDC59_RS10775 86ebb58de5ef32e2aea22cdd09c1d2ae 635 SUPERFAMILY SSF103473 12 433 7.32E-30 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS10775 86ebb58de5ef32e2aea22cdd09c1d2ae 635 Gene3D G3DSA:1.20.1250.20 3 209 4.8E-12 T 29-03-2018 CDC59_RS10775 86ebb58de5ef32e2aea22cdd09c1d2ae 635 SMART SM00563 464 580 9.5E-29 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CDC59_RS10775 86ebb58de5ef32e2aea22cdd09c1d2ae 635 Pfam PF01553 Acyltransferase 449 576 1.2E-27 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CDC59_RS10775 86ebb58de5ef32e2aea22cdd09c1d2ae 635 Gene3D G3DSA:1.20.1250.20 219 424 5.5E-18 T 29-03-2018 CDC59_RS10775 86ebb58de5ef32e2aea22cdd09c1d2ae 635 SUPERFAMILY SSF69593 392 615 2.48E-35 T 29-03-2018 CDC59_RS10775 86ebb58de5ef32e2aea22cdd09c1d2ae 635 Gene3D G3DSA:3.40.1130.10 425 631 8.0E-41 T 29-03-2018 CDC59_RS01195 9d7683b117cee975a1802fa4359ed790 152 Gene3D G3DSA:3.40.1260.10 34 152 1.2E-26 T 29-03-2018 CDC59_RS01195 9d7683b117cee975a1802fa4359ed790 152 SUPERFAMILY SSF75169 37 152 4.32E-22 T 29-03-2018 IPR027396 DsrEFH-like CDC59_RS01195 9d7683b117cee975a1802fa4359ed790 152 Pfam PF02635 DsrE/DsrF-like family 56 152 4.0E-13 T 29-03-2018 IPR003787 Sulphur relay, DsrE/F-like protein CDC59_RS23205 ec27b5346ac144f34d7ca93819a9a06f 158 SUPERFAMILY SSF54427 38 152 1.37E-29 T 29-03-2018 IPR032710 NTF2-like domain CDC59_RS23205 ec27b5346ac144f34d7ca93819a9a06f 158 PIRSF PIRSF028470 1 158 6.9E-64 T 29-03-2018 IPR016887 Uncharacterised conserved protein UCP028470, steroid isomerase-related CDC59_RS23205 ec27b5346ac144f34d7ca93819a9a06f 158 Pfam PF08332 Calcium/calmodulin dependent protein kinase II association domain 38 155 9.3E-20 T 29-03-2018 IPR013543 Calcium/calmodulin-dependent protein kinase II, association-domain GO:0004683|GO:0005516|GO:0006468 Reactome: R-HSA-3371571|Reactome: R-HSA-399719|Reactome: R-HSA-438066|Reactome: R-HSA-442729|Reactome: R-HSA-442742|Reactome: R-HSA-442982|Reactome: R-HSA-5576892|Reactome: R-HSA-5578775|Reactome: R-HSA-5673001|Reactome: R-HSA-877300|Reactome: R-HSA-936837 CDC59_RS23205 ec27b5346ac144f34d7ca93819a9a06f 158 TIGRFAM TIGR02246 TIGR02246: conserved hypothetical protein 38 155 2.8E-17 T 29-03-2018 IPR011944 Steroid delta5-4-isomerase KEGG: 00140+5.3.3.1|KEGG: 00984+5.3.3.1|MetaCyc: PWY-2582|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-699|MetaCyc: PWY-7299 CDC59_RS23205 ec27b5346ac144f34d7ca93819a9a06f 158 Gene3D G3DSA:3.10.450.50 20 158 1.4E-25 T 29-03-2018 CDC59_RS20405 4996b95b553de8ae2e2e47ccd49e926e 345 SUPERFAMILY SSF51735 145 309 3.29E-33 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS20405 4996b95b553de8ae2e2e47ccd49e926e 345 SMART SM00829 8 342 0.0028 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CDC59_RS20405 4996b95b553de8ae2e2e47ccd49e926e 345 Gene3D G3DSA:3.90.180.10 2 162 2.0E-45 T 29-03-2018 CDC59_RS20405 4996b95b553de8ae2e2e47ccd49e926e 345 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CDC59_RS20405 4996b95b553de8ae2e2e47ccd49e926e 345 Gene3D G3DSA:3.40.50.720 163 318 2.9E-29 T 29-03-2018 CDC59_RS20405 4996b95b553de8ae2e2e47ccd49e926e 345 SUPERFAMILY SSF50129 2 179 2.74E-50 T 29-03-2018 IPR011032 GroES-like CDC59_RS20405 4996b95b553de8ae2e2e47ccd49e926e 345 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 139 2.0E-29 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CDC59_RS20405 4996b95b553de8ae2e2e47ccd49e926e 345 Pfam PF00107 Zinc-binding dehydrogenase 180 304 5.6E-18 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CDC59_RS09810 8420b54eef1d8b888a7a0a9aeb4196c7 332 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 5 328 6.5E-80 T 29-03-2018 IPR003770 Endolytic murein transglycosylase CDC59_RS09810 8420b54eef1d8b888a7a0a9aeb4196c7 332 Gene3D G3DSA:3.30.160.60 72 106 4.9E-10 T 29-03-2018 CDC59_RS09810 8420b54eef1d8b888a7a0a9aeb4196c7 332 Pfam PF02618 YceG-like family 40 326 6.1E-82 T 29-03-2018 IPR003770 Endolytic murein transglycosylase CDC59_RS09810 8420b54eef1d8b888a7a0a9aeb4196c7 332 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 5 329 33.352 T 29-03-2018 IPR003770 Endolytic murein transglycosylase CDC59_RS09810 8420b54eef1d8b888a7a0a9aeb4196c7 332 Gene3D G3DSA:3.30.160.60 301 331 5.4E-13 T 29-03-2018 CDC59_RS14460 1d292e813877e9a206625dc27a81e3ae 534 Gene3D G3DSA:1.20.210.10 25 534 1.7E-223 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS14460 1d292e813877e9a206625dc27a81e3ae 534 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 30 533 5.1E-212 T 29-03-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 CDC59_RS14460 1d292e813877e9a206625dc27a81e3ae 534 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 257 311 - T 29-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS14460 1d292e813877e9a206625dc27a81e3ae 534 PRINTS PR01165 Cytochrome c oxidase subunit I signature 301 316 1.1E-121 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS14460 1d292e813877e9a206625dc27a81e3ae 534 PRINTS PR01165 Cytochrome c oxidase subunit I signature 325 346 1.1E-121 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS14460 1d292e813877e9a206625dc27a81e3ae 534 PRINTS PR01165 Cytochrome c oxidase subunit I signature 103 127 1.1E-121 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS14460 1d292e813877e9a206625dc27a81e3ae 534 PRINTS PR01165 Cytochrome c oxidase subunit I signature 29 54 1.1E-121 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS14460 1d292e813877e9a206625dc27a81e3ae 534 PRINTS PR01165 Cytochrome c oxidase subunit I signature 146 158 1.1E-121 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS14460 1d292e813877e9a206625dc27a81e3ae 534 PRINTS PR01165 Cytochrome c oxidase subunit I signature 255 276 1.1E-121 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS14460 1d292e813877e9a206625dc27a81e3ae 534 PRINTS PR01165 Cytochrome c oxidase subunit I signature 360 378 1.1E-121 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS14460 1d292e813877e9a206625dc27a81e3ae 534 PRINTS PR01165 Cytochrome c oxidase subunit I signature 76 99 1.1E-121 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS14460 1d292e813877e9a206625dc27a81e3ae 534 PRINTS PR01165 Cytochrome c oxidase subunit I signature 388 407 1.1E-121 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS14460 1d292e813877e9a206625dc27a81e3ae 534 PRINTS PR01165 Cytochrome c oxidase subunit I signature 438 459 1.1E-121 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS14460 1d292e813877e9a206625dc27a81e3ae 534 PRINTS PR01165 Cytochrome c oxidase subunit I signature 175 193 1.1E-121 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS14460 1d292e813877e9a206625dc27a81e3ae 534 PRINTS PR01165 Cytochrome c oxidase subunit I signature 204 223 1.1E-121 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS14460 1d292e813877e9a206625dc27a81e3ae 534 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 38 478 2.3E-152 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS14460 1d292e813877e9a206625dc27a81e3ae 534 SUPERFAMILY SSF81442 26 533 3.14E-194 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS15950 9af9e7b5602f2b3ba43c0dcaf76ed597 371 Gene3D G3DSA:3.10.150.10 253 371 1.9E-29 T 29-03-2018 CDC59_RS15950 9af9e7b5602f2b3ba43c0dcaf76ed597 371 Pfam PF02767 DNA polymerase III beta subunit, central domain 130 248 6.6E-34 T 29-03-2018 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDC59_RS15950 9af9e7b5602f2b3ba43c0dcaf76ed597 371 PIRSF PIRSF000804 1 371 2.3E-113 T 29-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDC59_RS15950 9af9e7b5602f2b3ba43c0dcaf76ed597 371 SUPERFAMILY SSF55979 250 371 3.61E-37 T 29-03-2018 CDC59_RS15950 9af9e7b5602f2b3ba43c0dcaf76ed597 371 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 6 370 1.3E-98 T 29-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDC59_RS15950 9af9e7b5602f2b3ba43c0dcaf76ed597 371 SUPERFAMILY SSF55979 5 117 6.28E-21 T 29-03-2018 CDC59_RS15950 9af9e7b5602f2b3ba43c0dcaf76ed597 371 Gene3D G3DSA:3.10.150.10 125 252 8.9E-31 T 29-03-2018 CDC59_RS15950 9af9e7b5602f2b3ba43c0dcaf76ed597 371 SMART SM00480 18 367 1.4E-112 T 29-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDC59_RS15950 9af9e7b5602f2b3ba43c0dcaf76ed597 371 Gene3D G3DSA:3.10.150.10 2 120 1.6E-22 T 29-03-2018 CDC59_RS15950 9af9e7b5602f2b3ba43c0dcaf76ed597 371 SUPERFAMILY SSF55979 128 249 2.9E-27 T 29-03-2018 CDC59_RS15950 9af9e7b5602f2b3ba43c0dcaf76ed597 371 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 251 370 1.1E-34 T 29-03-2018 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDC59_RS15950 9af9e7b5602f2b3ba43c0dcaf76ed597 371 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 7 119 2.4E-27 T 29-03-2018 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDC59_RS06965 5312471742d3bd866ff6ade0990d344f 427 Gene3D G3DSA:3.30.450.20 282 427 3.3E-11 T 29-03-2018 CDC59_RS06965 5312471742d3bd866ff6ade0990d344f 427 Pfam PF05231 MASE1 13 296 1.1E-57 T 29-03-2018 IPR007895 MASE1 CDC59_RS06965 5312471742d3bd866ff6ade0990d344f 427 SUPERFAMILY SSF55785 294 417 2.79E-9 T 29-03-2018 IPR000014 PAS domain CDC59_RS06965 5312471742d3bd866ff6ade0990d344f 427 Pfam PF08447 PAS fold 331 420 2.4E-6 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 CDC59_RS13745 2ccfe9f6ad066702af4be4ec17cf8045 237 TIGRFAM TIGR00697 TIGR00697: conserved hypothetical integral membrane protein 18 217 1.5E-29 T 29-03-2018 IPR003744 Queuosine precursor transporter CDC59_RS13745 2ccfe9f6ad066702af4be4ec17cf8045 237 Pfam PF02592 Putative vitamin uptake transporter 51 210 1.7E-46 T 29-03-2018 IPR003744 Queuosine precursor transporter CDC59_RS22640 ca1b799285a91e8e028786eeff3b8cce 393 SUPERFAMILY SSF52540 12 275 1.8E-19 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS22640 ca1b799285a91e8e028786eeff3b8cce 393 Gene3D G3DSA:3.40.50.300 12 276 1.4E-4 T 29-03-2018 CDC59_RS22640 ca1b799285a91e8e028786eeff3b8cce 393 Gene3D G3DSA:1.10.10.10 296 379 7.8E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS19910 15bccfce3edddf924a2a8adfda893a66 407 TIGRFAM TIGR03364 HpnW_proposed: FAD dependent oxidoreductase TIGR03364 15 381 9.1E-128 T 29-03-2018 IPR017741 FAD-dependent oxidoreductase, HpnW CDC59_RS19910 15bccfce3edddf924a2a8adfda893a66 407 Gene3D G3DSA:3.30.9.10 194 342 6.7E-7 T 29-03-2018 CDC59_RS19910 15bccfce3edddf924a2a8adfda893a66 407 Gene3D G3DSA:3.50.50.60 1 193 1.2E-17 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS19910 15bccfce3edddf924a2a8adfda893a66 407 Pfam PF01266 FAD dependent oxidoreductase 16 381 5.7E-31 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CDC59_RS19910 15bccfce3edddf924a2a8adfda893a66 407 SUPERFAMILY SSF51905 15 223 3.11E-28 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS19910 15bccfce3edddf924a2a8adfda893a66 407 SUPERFAMILY SSF51905 371 387 3.11E-28 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS03960 74367c0e45868e95517e1c2e11255095 472 Gene3D G3DSA:3.30.465.10 106 249 9.2E-49 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CDC59_RS03960 74367c0e45868e95517e1c2e11255095 472 SUPERFAMILY SSF56176 11 227 2.43E-73 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CDC59_RS03960 74367c0e45868e95517e1c2e11255095 472 Pfam PF01565 FAD binding domain 53 189 3.7E-41 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CDC59_RS03960 74367c0e45868e95517e1c2e11255095 472 Pfam PF02913 FAD linked oxidases, C-terminal domain 227 469 1.3E-60 T 29-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CDC59_RS03960 74367c0e45868e95517e1c2e11255095 472 Gene3D G3DSA:3.30.43.10 3 105 1.3E-25 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CDC59_RS03960 74367c0e45868e95517e1c2e11255095 472 SUPERFAMILY SSF55103 230 470 9.32E-73 T 29-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CDC59_RS03960 74367c0e45868e95517e1c2e11255095 472 Gene3D G3DSA:1.10.45.10 430 469 2.7E-17 T 29-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CDC59_RS22280 a040c3cce4a9c3efc1d4b0fe5e6e2f71 132 Pfam PF03994 Domain of Unknown Function (DUF350) 79 131 5.8E-10 T 29-03-2018 IPR007140 Protein of unknown function DUF350 CDC59_RS22280 a040c3cce4a9c3efc1d4b0fe5e6e2f71 132 Pfam PF03994 Domain of Unknown Function (DUF350) 16 67 5.8E-13 T 29-03-2018 IPR007140 Protein of unknown function DUF350 CDC59_RS05780 3ec5043623a7b053f316c8c7beae5102 434 PIRSF PIRSF000390 33 418 4.3E-67 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CDC59_RS05780 3ec5043623a7b053f316c8c7beae5102 434 SUPERFAMILY SSF53383 41 415 2.13E-70 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS05780 3ec5043623a7b053f316c8c7beae5102 434 Gene3D G3DSA:3.40.640.10 18 273 2.3E-39 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDC59_RS05780 3ec5043623a7b053f316c8c7beae5102 434 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 60 411 3.0E-62 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CDC59_RS05780 3ec5043623a7b053f316c8c7beae5102 434 Gene3D G3DSA:3.90.1150.10 274 426 3.5E-15 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS13835 726826dbb91b525ef61571f819fbd6a4 244 Pfam PF00005 ABC transporter 18 165 3.4E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS13835 726826dbb91b525ef61571f819fbd6a4 244 Gene3D G3DSA:3.40.50.300 1 241 9.6E-68 T 29-03-2018 CDC59_RS13835 726826dbb91b525ef61571f819fbd6a4 244 SUPERFAMILY SSF52540 1 228 1.59E-73 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS13835 726826dbb91b525ef61571f819fbd6a4 244 SMART SM00382 26 213 2.4E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS13835 726826dbb91b525ef61571f819fbd6a4 244 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS13835 726826dbb91b525ef61571f819fbd6a4 244 PIRSF PIRSF039085 1 243 5.1E-100 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CDC59_RS05390 778c7d4bf869b30401da7ace59ce2fbf 357 SUPERFAMILY SSF51395 1 353 3.4E-110 T 29-03-2018 CDC59_RS05390 778c7d4bf869b30401da7ace59ce2fbf 357 Gene3D G3DSA:3.20.20.70 1 357 5.4E-111 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS05390 778c7d4bf869b30401da7ace59ce2fbf 357 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 329 9.0E-79 T 29-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CDC59_RS23865 a24dc8b0efc4a46619f91a5719b324ca 208 Gene3D G3DSA:1.10.1740.10 12 84 4.2E-16 T 29-03-2018 CDC59_RS23865 a24dc8b0efc4a46619f91a5719b324ca 208 Pfam PF08281 Sigma-70, region 4 123 175 8.8E-17 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS23865 a24dc8b0efc4a46619f91a5719b324ca 208 SUPERFAMILY SSF88946 16 96 1.96E-16 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS23865 a24dc8b0efc4a46619f91a5719b324ca 208 SUPERFAMILY SSF88659 120 179 3.36E-16 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS23865 a24dc8b0efc4a46619f91a5719b324ca 208 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 18 177 8.5E-25 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS23865 a24dc8b0efc4a46619f91a5719b324ca 208 Pfam PF04542 Sigma-70 region 2 24 86 2.1E-12 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS23865 a24dc8b0efc4a46619f91a5719b324ca 208 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 43 73 - T 29-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS23865 a24dc8b0efc4a46619f91a5719b324ca 208 Gene3D G3DSA:1.10.10.10 85 182 2.9E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS05880 d08995e0bc7e7e142a1862e627d0a221 436 Gene3D G3DSA:3.20.20.70 143 358 4.1E-25 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS05880 d08995e0bc7e7e142a1862e627d0a221 436 SMART SM01091 347 427 5.6E-27 T 29-03-2018 IPR005170 Transporter-associated domain CDC59_RS05880 d08995e0bc7e7e142a1862e627d0a221 436 Gene3D G3DSA:3.30.465.10 359 426 4.9E-21 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CDC59_RS05880 d08995e0bc7e7e142a1862e627d0a221 436 SUPERFAMILY SSF56176 345 430 7.09E-21 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CDC59_RS05880 d08995e0bc7e7e142a1862e627d0a221 436 SUPERFAMILY SSF54631 198 337 1.18E-22 T 29-03-2018 CDC59_RS05880 d08995e0bc7e7e142a1862e627d0a221 436 Pfam PF00571 CBS domain 284 334 2.9E-6 T 29-03-2018 IPR000644 CBS domain CDC59_RS05880 d08995e0bc7e7e142a1862e627d0a221 436 Pfam PF03471 Transporter associated domain 348 425 1.4E-19 T 29-03-2018 IPR005170 Transporter-associated domain CDC59_RS05880 d08995e0bc7e7e142a1862e627d0a221 436 Pfam PF01595 Domain of unknown function DUF21 5 195 4.6E-41 T 29-03-2018 IPR002550 Domain of unknown function DUF21 CDC59_RS16880 58fd363e738796ef6d8a93d7e09a17a7 155 SUPERFAMILY SSF52402 1 146 1.42E-26 T 29-03-2018 CDC59_RS16880 58fd363e738796ef6d8a93d7e09a17a7 155 PRINTS PR01438 Universal stress protein signature 2 20 2.1E-14 T 29-03-2018 IPR006015 Universal stress protein A CDC59_RS16880 58fd363e738796ef6d8a93d7e09a17a7 155 PRINTS PR01438 Universal stress protein signature 106 118 2.1E-14 T 29-03-2018 IPR006015 Universal stress protein A CDC59_RS16880 58fd363e738796ef6d8a93d7e09a17a7 155 PRINTS PR01438 Universal stress protein signature 124 146 2.1E-14 T 29-03-2018 IPR006015 Universal stress protein A CDC59_RS16880 58fd363e738796ef6d8a93d7e09a17a7 155 Gene3D G3DSA:3.40.50.620 1 150 8.5E-28 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDC59_RS16880 58fd363e738796ef6d8a93d7e09a17a7 155 Pfam PF00582 Universal stress protein family 1 146 6.9E-27 T 29-03-2018 IPR006016 UspA GO:0006950 CDC59_RS02560 fe072ec98d2ad744aca89daa6b4f3432 78 SUPERFAMILY SSF82657 1 77 1.44E-29 T 29-03-2018 IPR002634 BolA protein CDC59_RS02560 fe072ec98d2ad744aca89daa6b4f3432 78 PIRSF PIRSF003113 1 78 1.6E-24 T 29-03-2018 IPR002634 BolA protein CDC59_RS02560 fe072ec98d2ad744aca89daa6b4f3432 78 Gene3D G3DSA:3.30.300.90 2 78 1.4E-29 T 29-03-2018 CDC59_RS02560 fe072ec98d2ad744aca89daa6b4f3432 78 Pfam PF01722 BolA-like protein 23 75 2.2E-20 T 29-03-2018 IPR002634 BolA protein CDC59_RS13040 72320a7ad6899613fcc451993e0a6581 358 Gene3D G3DSA:3.30.2010.10 148 242 5.5E-14 T 29-03-2018 CDC59_RS13040 72320a7ad6899613fcc451993e0a6581 358 Pfam PF01435 Peptidase family M48 164 347 1.2E-22 T 29-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CDC59_RS10750 f2e949e414953fd4eaa655e6c6d1070e 181 Gene3D G3DSA:3.30.450.20 3 122 2.4E-15 T 29-03-2018 CDC59_RS10750 f2e949e414953fd4eaa655e6c6d1070e 181 SMART SM00421 121 178 1.4E-16 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS10750 f2e949e414953fd4eaa655e6c6d1070e 181 SMART SM00091 4 70 0.0031 T 29-03-2018 IPR000014 PAS domain CDC59_RS10750 f2e949e414953fd4eaa655e6c6d1070e 181 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 124 138 1.4E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS10750 f2e949e414953fd4eaa655e6c6d1070e 181 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 166 1.4E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS10750 f2e949e414953fd4eaa655e6c6d1070e 181 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 138 154 1.4E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS10750 f2e949e414953fd4eaa655e6c6d1070e 181 SUPERFAMILY SSF55785 6 113 2.44E-13 T 29-03-2018 IPR000014 PAS domain CDC59_RS10750 f2e949e414953fd4eaa655e6c6d1070e 181 SUPERFAMILY SSF46894 109 180 4.42E-17 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CDC59_RS10750 f2e949e414953fd4eaa655e6c6d1070e 181 Pfam PF13426 PAS domain 14 115 1.3E-10 T 29-03-2018 IPR000014 PAS domain CDC59_RS10750 f2e949e414953fd4eaa655e6c6d1070e 181 ProSitePatterns PS00622 LuxR-type HTH domain signature. 138 165 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS10750 f2e949e414953fd4eaa655e6c6d1070e 181 Gene3D G3DSA:1.10.10.10 123 181 1.1E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS10750 f2e949e414953fd4eaa655e6c6d1070e 181 Pfam PF00196 Bacterial regulatory proteins, luxR family 123 175 9.4E-16 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS10750 f2e949e414953fd4eaa655e6c6d1070e 181 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 6 100 1.6E-10 T 29-03-2018 IPR000014 PAS domain CDC59_RS01485 18924e7926f64e5d6177aff3bb2c6b7b 411 Gene3D G3DSA:3.40.640.10 35 278 1.7E-34 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDC59_RS01485 18924e7926f64e5d6177aff3bb2c6b7b 411 Gene3D G3DSA:3.90.1150.10 279 404 1.4E-8 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS01485 18924e7926f64e5d6177aff3bb2c6b7b 411 SUPERFAMILY SSF53383 9 390 6.74E-63 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS01485 18924e7926f64e5d6177aff3bb2c6b7b 411 Pfam PF00266 Aminotransferase class-V 58 380 2.6E-22 T 29-03-2018 IPR000192 Aminotransferase class V domain CDC59_RS23400 500482a76ca7eb4780451bc284e77727 654 Pfam PF05876 Phage terminase large subunit (GpA) 36 599 5.4E-189 T 29-03-2018 IPR008866 Bacteriophage lambda, GpA CDC59_RS01540 e1021752c34439654b2dac1a2688fb3f 387 Pfam PF13458 Periplasmic binding protein 28 370 5.5E-33 T 29-03-2018 IPR028081 Leucine-binding protein domain CDC59_RS01540 e1021752c34439654b2dac1a2688fb3f 387 Gene3D G3DSA:3.40.50.2300 206 371 1.0E-11 T 29-03-2018 CDC59_RS01540 e1021752c34439654b2dac1a2688fb3f 387 Gene3D G3DSA:3.40.50.2300 24 195 1.4E-13 T 29-03-2018 CDC59_RS01540 e1021752c34439654b2dac1a2688fb3f 387 SUPERFAMILY SSF53822 26 376 1.18E-38 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CDC59_RS14210 7aa612e03e16fc877dacc8fe3b652733 327 Gene3D G3DSA:3.40.50.10490 4 202 6.8E-57 T 29-03-2018 CDC59_RS14210 7aa612e03e16fc877dacc8fe3b652733 327 Pfam PF01380 SIS domain 44 175 2.8E-32 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CDC59_RS14210 7aa612e03e16fc877dacc8fe3b652733 327 Gene3D G3DSA:3.10.580.10 203 325 8.7E-24 T 29-03-2018 CDC59_RS14210 7aa612e03e16fc877dacc8fe3b652733 327 SUPERFAMILY SSF53697 11 324 3.34E-66 T 29-03-2018 CDC59_RS14210 7aa612e03e16fc877dacc8fe3b652733 327 SMART SM00116 213 261 5.0 T 29-03-2018 IPR000644 CBS domain CDC59_RS14210 7aa612e03e16fc877dacc8fe3b652733 327 SMART SM00116 278 326 0.0013 T 29-03-2018 IPR000644 CBS domain CDC59_RS14210 7aa612e03e16fc877dacc8fe3b652733 327 Pfam PF00571 CBS domain 271 324 5.8E-8 T 29-03-2018 IPR000644 CBS domain CDC59_RS14210 7aa612e03e16fc877dacc8fe3b652733 327 Pfam PF00571 CBS domain 204 260 7.5E-6 T 29-03-2018 IPR000644 CBS domain CDC59_RS14210 7aa612e03e16fc877dacc8fe3b652733 327 TIGRFAM TIGR00393 kpsF: sugar isomerase, KpsF/GutQ family 48 317 7.6E-105 T 29-03-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 CDC59_RS14210 7aa612e03e16fc877dacc8fe3b652733 327 PIRSF PIRSF004692 2 327 2.1E-131 T 29-03-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 CDC59_RS23135 46756600e1729dc0c0066e4a21294c38 148 Gene3D G3DSA:1.20.120.330 10 127 2.4E-5 T 29-03-2018 CDC59_RS23135 46756600e1729dc0c0066e4a21294c38 148 Pfam PF14282 FlxA-like protein 8 103 5.1E-20 T 29-03-2018 IPR025577 FlxA-like protein CDC59_RS07220 73dab682a4f0ae36fb71799ac5e8a854 334 Gene3D G3DSA:3.40.50.720 2 113 4.7E-29 T 29-03-2018 CDC59_RS07220 73dab682a4f0ae36fb71799ac5e8a854 334 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 287 5.6E-57 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CDC59_RS07220 73dab682a4f0ae36fb71799ac5e8a854 334 SUPERFAMILY SSF52283 2 135 2.84E-32 T 29-03-2018 CDC59_RS07220 73dab682a4f0ae36fb71799ac5e8a854 334 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 5 310 1.3E-22 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CDC59_RS07220 73dab682a4f0ae36fb71799ac5e8a854 334 Gene3D G3DSA:3.40.50.720 114 290 2.9E-52 T 29-03-2018 CDC59_RS07220 73dab682a4f0ae36fb71799ac5e8a854 334 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 149 176 - T 29-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 CDC59_RS07220 73dab682a4f0ae36fb71799ac5e8a854 334 SUPERFAMILY SSF51735 101 288 3.82E-58 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS07630 a49380be75c288babce8a3bf09926803 416 Pfam PF12704 MacB-like periplasmic core domain 30 243 2.2E-19 T 29-03-2018 IPR025857 MacB-like periplasmic core domain CDC59_RS07630 a49380be75c288babce8a3bf09926803 416 Pfam PF02687 FtsX-like permease family 303 409 2.6E-14 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CDC59_RS07630 a49380be75c288babce8a3bf09926803 416 TIGRFAM TIGR02212 lolCE: lipoprotein releasing system, transmembrane protein, LolC/E family 6 416 1.5E-146 T 29-03-2018 IPR011925 Lipoprotein-releasing system transmembrane protein LolC/E GO:0016021|GO:0042953|GO:0042954 CDC59_RS16970 45dbd3d3c8ad095b0d0d3eb5fd26a9cf 96 Pfam PF00816 H-NS histone family 6 88 8.8E-27 T 29-03-2018 IPR001801 Histone-like protein H-NS GO:0003677|GO:0005622|GO:0006355 CDC59_RS16970 45dbd3d3c8ad095b0d0d3eb5fd26a9cf 96 Gene3D G3DSA:4.10.430.10 63 95 6.7E-15 T 29-03-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 CDC59_RS16970 45dbd3d3c8ad095b0d0d3eb5fd26a9cf 96 SUPERFAMILY SSF81273 60 95 7.06E-10 T 29-03-2018 CDC59_RS16970 45dbd3d3c8ad095b0d0d3eb5fd26a9cf 96 SMART SM00528 57 95 3.0E-9 T 29-03-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 CDC59_RS04165 6b5a0e6d54eefb0bd3ef0608fc1b5d2a 356 SUPERFAMILY SSF56042 182 352 2.09E-60 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CDC59_RS04165 6b5a0e6d54eefb0bd3ef0608fc1b5d2a 356 Pfam PF02769 AIR synthase related protein, C-terminal domain 188 347 3.7E-36 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CDC59_RS04165 6b5a0e6d54eefb0bd3ef0608fc1b5d2a 356 Gene3D G3DSA:3.30.1330.10 44 172 1.1E-52 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CDC59_RS04165 6b5a0e6d54eefb0bd3ef0608fc1b5d2a 356 SUPERFAMILY SSF55326 18 181 9.24E-53 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CDC59_RS04165 6b5a0e6d54eefb0bd3ef0608fc1b5d2a 356 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 18 345 2.8E-137 T 29-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CDC59_RS04165 6b5a0e6d54eefb0bd3ef0608fc1b5d2a 356 Pfam PF00586 AIR synthase related protein, N-terminal domain 71 174 1.7E-15 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CDC59_RS04165 6b5a0e6d54eefb0bd3ef0608fc1b5d2a 356 Gene3D G3DSA:3.90.650.10 182 356 1.6E-63 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CDC59_RS04165 6b5a0e6d54eefb0bd3ef0608fc1b5d2a 356 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 18 355 46.92 T 29-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CDC59_RS11320 e108134faa87df235815c60fcd492a27 221 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 142 219 5.4E-19 T 29-03-2018 IPR006260 TonB, C-terminal GO:0006810 CDC59_RS11320 e108134faa87df235815c60fcd492a27 221 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 145 219 3.9E-16 T 29-03-2018 IPR006260 TonB, C-terminal GO:0006810 CDC59_RS11320 e108134faa87df235815c60fcd492a27 221 PRINTS PR01374 Gram-negative bacterial tonB protein signature 158 176 2.3E-5 T 29-03-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 CDC59_RS11320 e108134faa87df235815c60fcd492a27 221 PRINTS PR01374 Gram-negative bacterial tonB protein signature 137 158 2.3E-5 T 29-03-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 CDC59_RS11320 e108134faa87df235815c60fcd492a27 221 PRINTS PR01374 Gram-negative bacterial tonB protein signature 77 87 2.3E-5 T 29-03-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 CDC59_RS11320 e108134faa87df235815c60fcd492a27 221 Gene3D G3DSA:3.30.1150.10 48 221 1.2E-16 T 29-03-2018 CDC59_RS11320 e108134faa87df235815c60fcd492a27 221 SUPERFAMILY SSF74653 105 220 3.27E-21 T 29-03-2018 CDC59_RS22930 6358c142262654060276d263e4cf64f5 375 Pfam PF13609 Gram-negative porin 11 342 1.7E-46 T 29-03-2018 CDC59_RS22930 6358c142262654060276d263e4cf64f5 375 Gene3D G3DSA:2.40.160.10 12 375 1.2E-58 T 29-03-2018 CDC59_RS22930 6358c142262654060276d263e4cf64f5 375 SUPERFAMILY SSF56935 26 375 4.27E-75 T 29-03-2018 CDC59_RS20675 f6a7649df012adee40d938945a6f15c2 638 Pfam PF00593 TonB dependent receptor 207 634 6.1E-31 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CDC59_RS20675 f6a7649df012adee40d938945a6f15c2 638 SUPERFAMILY SSF56935 24 638 1.39E-84 T 29-03-2018 CDC59_RS20675 f6a7649df012adee40d938945a6f15c2 638 Pfam PF07715 TonB-dependent Receptor Plug Domain 48 153 2.9E-15 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CDC59_RS20675 f6a7649df012adee40d938945a6f15c2 638 Gene3D G3DSA:2.40.170.20 168 638 2.5E-53 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CDC59_RS20675 f6a7649df012adee40d938945a6f15c2 638 Gene3D G3DSA:2.170.130.10 42 167 1.7E-17 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CDC59_RS12295 bc376403edcf3478b6e5c44394720905 293 Gene3D G3DSA:1.10.10.580 218 288 1.6E-14 T 29-03-2018 CDC59_RS12295 bc376403edcf3478b6e5c44394720905 293 Pfam PF02616 Segregation and condensation protein ScpA 73 288 7.9E-34 T 29-03-2018 IPR003768 Segregation and condensation protein A CDC59_RS12295 bc376403edcf3478b6e5c44394720905 293 Hamap MF_01805 Segregation and condensation protein A [scpA]. 56 290 21.038 T 29-03-2018 IPR003768 Segregation and condensation protein A CDC59_RS11150 d383c08e28467a888639b648efca17f1 200 Pfam PF04366 Las17-binding protein actin regulator 113 197 1.2E-14 T 29-03-2018 IPR007461 Ysc84 actin-binding domain CDC59_RS16480 adec902ca1226f7686b9368ac2aefcbb 327 SUPERFAMILY SSF103481 217 308 4.71E-11 T 29-03-2018 CDC59_RS16480 adec902ca1226f7686b9368ac2aefcbb 327 Pfam PF00892 EamA-like transporter family 40 171 9.0E-12 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CDC59_RS16480 adec902ca1226f7686b9368ac2aefcbb 327 SUPERFAMILY SSF103481 87 175 7.98E-10 T 29-03-2018 CDC59_RS13285 25621046881910e03393e2c1657943f2 392 Gene3D G3DSA:1.20.1250.20 210 389 8.2E-11 T 29-03-2018 CDC59_RS13285 25621046881910e03393e2c1657943f2 392 Gene3D G3DSA:1.20.1250.20 14 202 2.5E-14 T 29-03-2018 CDC59_RS13285 25621046881910e03393e2c1657943f2 392 SUPERFAMILY SSF103473 18 386 4.32E-34 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS13285 25621046881910e03393e2c1657943f2 392 Pfam PF07690 Major Facilitator Superfamily 27 345 2.1E-20 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDC59_RS14290 c831e3c5c9ab13e4bd1544a608358d96 209 Pfam PF03550 Outer membrane lipoprotein LolB 46 209 5.7E-38 T 29-03-2018 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 CDC59_RS14290 c831e3c5c9ab13e4bd1544a608358d96 209 TIGRFAM TIGR00548 lolB: outer membrane lipoprotein LolB 42 175 4.7E-19 T 29-03-2018 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 CDC59_RS14290 c831e3c5c9ab13e4bd1544a608358d96 209 Hamap MF_00233 Outer-membrane lipoprotein LolB [lolB]. 7 209 20.489 T 29-03-2018 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 CDC59_RS14290 c831e3c5c9ab13e4bd1544a608358d96 209 Gene3D G3DSA:2.50.20.10 25 209 1.6E-30 T 29-03-2018 CDC59_RS14290 c831e3c5c9ab13e4bd1544a608358d96 209 SUPERFAMILY SSF89392 23 209 9.42E-35 T 29-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX CDC59_RS06350 e3e9a37188f9db3e7bb6bde800ced8ee 384 Gene3D G3DSA:3.40.50.2300 51 169 9.0E-34 T 29-03-2018 CDC59_RS06350 e3e9a37188f9db3e7bb6bde800ced8ee 384 SUPERFAMILY SSF53822 210 297 5.23E-5 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CDC59_RS06350 e3e9a37188f9db3e7bb6bde800ced8ee 384 Gene3D G3DSA:3.40.50.2300 170 384 3.2E-54 T 29-03-2018 CDC59_RS06350 e3e9a37188f9db3e7bb6bde800ced8ee 384 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 54 338 1.1E-66 T 29-03-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 CDC59_RS06715 5c8c042a238b8bd2b4fe159f09a7ad4c 358 Pfam PF07995 Glucose / Sorbosone dehydrogenase 119 351 8.9E-16 T 29-03-2018 IPR012938 Glucose/Sorbosone dehydrogenase CDC59_RS06715 5c8c042a238b8bd2b4fe159f09a7ad4c 358 Gene3D G3DSA:2.120.10.30 14 240 5.8E-35 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CDC59_RS06715 5c8c042a238b8bd2b4fe159f09a7ad4c 358 Gene3D G3DSA:2.120.10.30 241 358 5.1E-23 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CDC59_RS06715 5c8c042a238b8bd2b4fe159f09a7ad4c 358 SUPERFAMILY SSF50952 15 357 6.54E-37 T 29-03-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 CDC59_RS13860 c31bfc1a9ed824f1e2918c420120a2b3 314 Gene3D G3DSA:3.40.190.10 78 188 5.3E-7 T 29-03-2018 CDC59_RS13860 c31bfc1a9ed824f1e2918c420120a2b3 314 SUPERFAMILY SSF46785 1 86 6.36E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS13860 c31bfc1a9ed824f1e2918c420120a2b3 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 4.8E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS13860 c31bfc1a9ed824f1e2918c420120a2b3 314 SUPERFAMILY SSF53850 90 268 9.77E-22 T 29-03-2018 CDC59_RS13860 c31bfc1a9ed824f1e2918c420120a2b3 314 Gene3D G3DSA:3.40.190.10 189 269 1.2E-10 T 29-03-2018 CDC59_RS13860 c31bfc1a9ed824f1e2918c420120a2b3 314 Pfam PF03466 LysR substrate binding domain 91 267 1.6E-20 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS13860 c31bfc1a9ed824f1e2918c420120a2b3 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.8E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS13860 c31bfc1a9ed824f1e2918c420120a2b3 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.8E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS13860 c31bfc1a9ed824f1e2918c420120a2b3 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.8E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS13860 c31bfc1a9ed824f1e2918c420120a2b3 314 Gene3D G3DSA:1.10.10.10 1 77 3.5E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS17090 3a45b68cafb334aee69680cb86313ff8 89 PIRSF PIRSF004669 1 89 5.8E-33 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CDC59_RS17090 3a45b68cafb334aee69680cb86313ff8 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 5.4E-23 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CDC59_RS17090 3a45b68cafb334aee69680cb86313ff8 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 5.4E-23 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CDC59_RS17090 3a45b68cafb334aee69680cb86313ff8 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 5.4E-23 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CDC59_RS17090 3a45b68cafb334aee69680cb86313ff8 89 Pfam PF01313 Bacterial export proteins, family 3 6 78 4.2E-30 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CDC59_RS17090 3a45b68cafb334aee69680cb86313ff8 89 TIGRFAM TIGR01402 fliQ: flagellar biosynthetic protein FliQ 1 87 7.5E-31 T 29-03-2018 IPR006305 Flagellar biosynthesis protein FliQ GO:0016021|GO:0044780 CDC59_RS00395 4cd0464b3574efca8ccefac77f16a219 253 SUPERFAMILY SSF52540 1 235 9.76E-80 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS00395 4cd0464b3574efca8ccefac77f16a219 253 Gene3D G3DSA:3.40.50.300 1 243 2.0E-75 T 29-03-2018 CDC59_RS00395 4cd0464b3574efca8ccefac77f16a219 253 Pfam PF00005 ABC transporter 17 165 1.0E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS00395 4cd0464b3574efca8ccefac77f16a219 253 PIRSF PIRSF039085 1 241 3.0E-121 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CDC59_RS00395 4cd0464b3574efca8ccefac77f16a219 253 SMART SM00382 26 213 9.9E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS00395 4cd0464b3574efca8ccefac77f16a219 253 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS21610 cbf8f39c8344fc75cb9276a50ab9491b 443 SUPERFAMILY SSF111369 58 299 5.49E-62 T 29-03-2018 CDC59_RS21610 cbf8f39c8344fc75cb9276a50ab9491b 443 Gene3D G3DSA:1.20.1600.10 34 299 6.7E-27 T 29-03-2018 CDC59_RS21610 cbf8f39c8344fc75cb9276a50ab9491b 443 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 71 293 1.1E-14 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CDC59_RS21610 cbf8f39c8344fc75cb9276a50ab9491b 443 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 46 374 1.2E-79 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 CDC59_RS22040 16a8371a28ba3edf11cd7b0f2e14919d 113 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 6 111 2.0E-34 T 29-03-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 CDC59_RS22040 16a8371a28ba3edf11cd7b0f2e14919d 113 Pfam PF13806 Rieske-like [2Fe-2S] domain 5 111 1.0E-41 T 29-03-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 CDC59_RS22040 16a8371a28ba3edf11cd7b0f2e14919d 113 Gene3D G3DSA:2.102.10.10 3 113 1.4E-22 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CDC59_RS22040 16a8371a28ba3edf11cd7b0f2e14919d 113 SUPERFAMILY SSF50022 4 111 1.68E-36 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CDC59_RS03205 ce44dad60788484dffd984919475a731 252 Gene3D G3DSA:1.10.3900.10 10 172 1.4E-65 T 29-03-2018 CDC59_RS03205 ce44dad60788484dffd984919475a731 252 Gene3D G3DSA:2.60.440.10 173 250 4.8E-27 T 29-03-2018 IPR027462 Z ring-associated protein D, C-terminal domain CDC59_RS03205 ce44dad60788484dffd984919475a731 252 Pfam PF07072 Cell division protein 16 226 2.8E-82 T 29-03-2018 IPR009777 Cell division protein ZapD CDC59_RS03205 ce44dad60788484dffd984919475a731 252 Hamap MF_01092 Cell division protein ZapD [zapD]. 1 250 33.222 T 29-03-2018 IPR009777 Cell division protein ZapD CDC59_RS03205 ce44dad60788484dffd984919475a731 252 SUPERFAMILY SSF160950 2 250 3.14E-88 T 29-03-2018 IPR009777 Cell division protein ZapD CDC59_RS23025 21faa0036362a15e2a80807b24ab0637 448 SUPERFAMILY SSF103473 5 421 3.27E-85 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS23025 21faa0036362a15e2a80807b24ab0637 448 PIRSF PIRSF002808 1 439 3.7E-39 T 29-03-2018 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 CDC59_RS23025 21faa0036362a15e2a80807b24ab0637 448 Gene3D G3DSA:1.20.1250.20 8 209 1.3E-39 T 29-03-2018 CDC59_RS23025 21faa0036362a15e2a80807b24ab0637 448 Pfam PF07690 Major Facilitator Superfamily 22 384 6.0E-63 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDC59_RS23025 21faa0036362a15e2a80807b24ab0637 448 Gene3D G3DSA:1.20.1250.20 220 423 3.0E-25 T 29-03-2018 CDC59_RS11410 3cabda8e3032a0b558b790f4063bf5b3 272 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 60 80 3.3E-30 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CDC59_RS11410 3cabda8e3032a0b558b790f4063bf5b3 272 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 25 39 3.3E-30 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CDC59_RS11410 3cabda8e3032a0b558b790f4063bf5b3 272 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 229 249 3.3E-30 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CDC59_RS11410 3cabda8e3032a0b558b790f4063bf5b3 272 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 206 224 3.3E-30 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CDC59_RS11410 3cabda8e3032a0b558b790f4063bf5b3 272 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 187 204 3.3E-30 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CDC59_RS11410 3cabda8e3032a0b558b790f4063bf5b3 272 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 29 35 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CDC59_RS11410 3cabda8e3032a0b558b790f4063bf5b3 272 Gene3D G3DSA:3.40.50.150 8 262 2.4E-61 T 29-03-2018 CDC59_RS11410 3cabda8e3032a0b558b790f4063bf5b3 272 SUPERFAMILY SSF53335 9 249 4.13E-65 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS11410 3cabda8e3032a0b558b790f4063bf5b3 272 Pfam PF01555 DNA methylase 26 244 5.6E-50 T 29-03-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 CDC59_RS04400 3668d82d3c3b17863d20b69a0cbdee0c 122 SMART SM00448 4 117 1.6E-39 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS04400 3668d82d3c3b17863d20b69a0cbdee0c 122 SUPERFAMILY SSF52172 5 120 1.57E-38 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS04400 3668d82d3c3b17863d20b69a0cbdee0c 122 Pfam PF00072 Response regulator receiver domain 6 117 3.5E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS04400 3668d82d3c3b17863d20b69a0cbdee0c 122 Gene3D G3DSA:3.40.50.2300 2 121 1.4E-38 T 29-03-2018 CDC59_RS09855 844055ebffe0d9c1393db15fc6d27abc 347 Gene3D G3DSA:3.40.190.10 30 148 9.4E-11 T 29-03-2018 CDC59_RS09855 844055ebffe0d9c1393db15fc6d27abc 347 SUPERFAMILY SSF53850 44 342 4.4E-64 T 29-03-2018 CDC59_RS09855 844055ebffe0d9c1393db15fc6d27abc 347 Gene3D G3DSA:3.40.190.10 149 302 1.3E-33 T 29-03-2018 CDC59_RS09855 844055ebffe0d9c1393db15fc6d27abc 347 Pfam PF13343 Bacterial extracellular solute-binding protein 87 332 5.4E-50 T 29-03-2018 CDC59_RS04625 c7bdc4fbe6f2472f9daf0dc58bacbbbe 155 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 16 147 20.982 T 29-03-2018 IPR011605 NusB antitermination factor GO:0006353 CDC59_RS04625 c7bdc4fbe6f2472f9daf0dc58bacbbbe 155 SUPERFAMILY SSF48013 15 147 4.58E-40 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CDC59_RS04625 c7bdc4fbe6f2472f9daf0dc58bacbbbe 155 Gene3D G3DSA:1.10.940.10 13 150 6.2E-37 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CDC59_RS04625 c7bdc4fbe6f2472f9daf0dc58bacbbbe 155 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 18 145 4.5E-37 T 29-03-2018 IPR011605 NusB antitermination factor GO:0006353 CDC59_RS04625 c7bdc4fbe6f2472f9daf0dc58bacbbbe 155 Pfam PF01029 NusB family 19 143 1.0E-31 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CDC59_RS15175 5a704013d21ee27f1fcb985e3a728b27 347 TIGRFAM TIGR03399 RNA_3prim_cycl: RNA 3'-phosphate cyclase 11 331 3.5E-117 T 29-03-2018 IPR017770 RNA 3'-terminal phosphate cyclase type 1 GO:0003963|GO:0006396 CDC59_RS15175 5a704013d21ee27f1fcb985e3a728b27 347 PIRSF PIRSF005378 8 347 2.9E-107 T 29-03-2018 IPR000228 RNA 3'-terminal phosphate cyclase GO:0006396 CDC59_RS15175 5a704013d21ee27f1fcb985e3a728b27 347 SUPERFAMILY SSF55205 277 339 2.81E-8 T 29-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CDC59_RS15175 5a704013d21ee27f1fcb985e3a728b27 347 Pfam PF01137 RNA 3'-terminal phosphate cyclase 18 333 6.9E-82 T 29-03-2018 IPR023797 RNA 3'-terminal phosphate cyclase domain CDC59_RS15175 5a704013d21ee27f1fcb985e3a728b27 347 ProSitePatterns PS01287 RNA 3'-terminal phosphate cyclase signature. 163 173 - T 29-03-2018 IPR020719 RNA 3'-terminal phosphate cyclase-like, conserved site CDC59_RS15175 5a704013d21ee27f1fcb985e3a728b27 347 Hamap MF_00200 RNA 3'-terminal phosphate cyclase [rtcA]. 10 345 38.222 T 29-03-2018 IPR017770 RNA 3'-terminal phosphate cyclase type 1 GO:0003963|GO:0006396 CDC59_RS15175 5a704013d21ee27f1fcb985e3a728b27 347 Gene3D G3DSA:3.65.10.20 10 342 3.7E-99 T 29-03-2018 IPR023797 RNA 3'-terminal phosphate cyclase domain CDC59_RS15175 5a704013d21ee27f1fcb985e3a728b27 347 Pfam PF05189 RNA 3'-terminal phosphate cyclase (RTC), insert domain 190 281 4.2E-7 T 29-03-2018 IPR013791 RNA 3'-terminal phosphate cyclase, insert domain CDC59_RS15175 5a704013d21ee27f1fcb985e3a728b27 347 SUPERFAMILY SSF52913 191 285 1.96E-21 T 29-03-2018 IPR013791 RNA 3'-terminal phosphate cyclase, insert domain CDC59_RS15175 5a704013d21ee27f1fcb985e3a728b27 347 SUPERFAMILY SSF55205 11 182 3.86E-64 T 29-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CDC59_RS18940 c6b55b05d75b0f3be31fefdddd766244 459 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 35 63 3.7E-7 T 29-03-2018 IPR006530 YD repeat CDC59_RS18940 c6b55b05d75b0f3be31fefdddd766244 459 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 176 205 0.0013 T 29-03-2018 IPR006530 YD repeat CDC59_RS18940 c6b55b05d75b0f3be31fefdddd766244 459 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 116 144 0.0014 T 29-03-2018 IPR006530 YD repeat CDC59_RS18940 c6b55b05d75b0f3be31fefdddd766244 459 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 357 390 5.2E-4 T 29-03-2018 IPR006530 YD repeat CDC59_RS18940 c6b55b05d75b0f3be31fefdddd766244 459 Pfam PF05593 RHS Repeat 19 49 1.7E-5 T 29-03-2018 IPR031325 RHS repeat CDC59_RS18940 c6b55b05d75b0f3be31fefdddd766244 459 Pfam PF05593 RHS Repeat 229 265 1.1E-4 T 29-03-2018 IPR031325 RHS repeat CDC59_RS18940 c6b55b05d75b0f3be31fefdddd766244 459 Pfam PF05593 RHS Repeat 35 66 6.0E-11 T 29-03-2018 IPR031325 RHS repeat CDC59_RS18940 c6b55b05d75b0f3be31fefdddd766244 459 Pfam PF05593 RHS Repeat 125 160 7.2E-10 T 29-03-2018 IPR031325 RHS repeat CDC59_RS18940 c6b55b05d75b0f3be31fefdddd766244 459 Pfam PF05593 RHS Repeat 177 214 7.6E-5 T 29-03-2018 IPR031325 RHS repeat CDC59_RS03935 6c78d7d74a693696e4fa6e21eb21ff3d 125 Pfam PF03788 LrgA family 12 105 2.1E-28 T 29-03-2018 IPR005538 LrgA/CidA family GO:0016021 CDC59_RS00830 e96c91e737fde0be5d72a86ae869289b 156 Gene3D G3DSA:1.20.5.620 62 122 4.2E-9 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CDC59_RS00830 e96c91e737fde0be5d72a86ae869289b 156 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 10 156 1.0E-41 T 29-03-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 CDC59_RS00830 e96c91e737fde0be5d72a86ae869289b 156 SUPERFAMILY SSF81573 62 121 6.41E-11 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CDC59_RS00830 e96c91e737fde0be5d72a86ae869289b 156 Pfam PF00430 ATP synthase B/B' CF(0) 6 136 2.6E-30 T 29-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CDC59_RS00830 e96c91e737fde0be5d72a86ae869289b 156 Hamap MF_01398 ATP synthase subunit b [atpF]. 1 138 12.698 T 29-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CDC59_RS10940 12028ededc67e6ed5f590685b60313a6 628 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 106 591 6.3E-234 T 29-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 CDC59_RS10940 12028ededc67e6ed5f590685b60313a6 628 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 4 597 37.17 T 29-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 CDC59_RS10940 12028ededc67e6ed5f590685b60313a6 628 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 190 322 3.5E-46 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CDC59_RS10940 12028ededc67e6ed5f590685b60313a6 628 Pfam PF01434 Peptidase family M41 384 590 6.8E-78 T 29-03-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 CDC59_RS10940 12028ededc67e6ed5f590685b60313a6 628 ProSitePatterns PS00674 AAA-protein family signature. 293 311 - T 29-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 CDC59_RS10940 12028ededc67e6ed5f590685b60313a6 628 Pfam PF06480 FtsH Extracellular 11 78 2.7E-8 T 29-03-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 CDC59_RS10940 12028ededc67e6ed5f590685b60313a6 628 SUPERFAMILY SSF52540 148 393 1.31E-73 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS10940 12028ededc67e6ed5f590685b60313a6 628 Gene3D G3DSA:1.10.8.60 334 412 1.3E-26 T 29-03-2018 CDC59_RS10940 12028ededc67e6ed5f590685b60313a6 628 Gene3D G3DSA:3.40.50.300 133 333 7.5E-64 T 29-03-2018 CDC59_RS10940 12028ededc67e6ed5f590685b60313a6 628 SUPERFAMILY SSF140990 404 599 1.23E-71 T 29-03-2018 CDC59_RS10940 12028ededc67e6ed5f590685b60313a6 628 SMART SM00382 186 325 2.5E-26 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS13190 b0e9073ef661b217d39e25ca9121d89e 547 Pfam PF02470 MlaD protein 292 396 4.1E-18 T 29-03-2018 IPR003399 Mce/MlaD CDC59_RS13190 b0e9073ef661b217d39e25ca9121d89e 547 Pfam PF02470 MlaD protein 49 139 1.2E-9 T 29-03-2018 IPR003399 Mce/MlaD CDC59_RS13190 b0e9073ef661b217d39e25ca9121d89e 547 Pfam PF02470 MlaD protein 164 224 5.8E-9 T 29-03-2018 IPR003399 Mce/MlaD CDC59_RS01985 9b18f17656efb9c2cb372016f656045b 432 Pfam PF07690 Major Facilitator Superfamily 19 368 1.6E-27 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDC59_RS01985 9b18f17656efb9c2cb372016f656045b 432 SUPERFAMILY SSF103473 10 420 2.09E-64 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS01985 9b18f17656efb9c2cb372016f656045b 432 Gene3D G3DSA:1.20.1250.20 219 427 1.7E-22 T 29-03-2018 CDC59_RS01985 9b18f17656efb9c2cb372016f656045b 432 ProSitePatterns PS00217 Sugar transport proteins signature 2. 123 148 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CDC59_RS01985 9b18f17656efb9c2cb372016f656045b 432 Gene3D G3DSA:1.20.1250.20 9 218 2.2E-23 T 29-03-2018 CDC59_RS15355 dddac698dfee6e3c19e6bac695c4725f 503 SUPERFAMILY SSF53720 18 488 1.01E-131 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CDC59_RS15355 dddac698dfee6e3c19e6bac695c4725f 503 Pfam PF00171 Aldehyde dehydrogenase family 24 480 6.1E-124 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CDC59_RS15355 dddac698dfee6e3c19e6bac695c4725f 503 Gene3D G3DSA:3.40.309.10 271 469 1.5E-49 T 29-03-2018 CDC59_RS15355 dddac698dfee6e3c19e6bac695c4725f 503 Gene3D G3DSA:3.40.605.10 18 270 3.7E-73 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CDC59_RS15355 dddac698dfee6e3c19e6bac695c4725f 503 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 254 261 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CDC59_RS05200 8662098c91a8c7f5daf4a4f429cefc58 210 Gene3D G3DSA:1.10.530.10 12 198 1.0E-24 T 29-03-2018 CDC59_RS05200 8662098c91a8c7f5daf4a4f429cefc58 210 SUPERFAMILY SSF53955 50 206 1.58E-28 T 29-03-2018 IPR023346 Lysozyme-like domain CDC59_RS05200 8662098c91a8c7f5daf4a4f429cefc58 210 Pfam PF01464 Transglycosylase SLT domain 60 160 2.8E-15 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 CDC59_RS00870 400e8395c6723467ace26c132e763b7c 153 SUPERFAMILY SSF51735 12 149 3.5E-41 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS00870 400e8395c6723467ace26c132e763b7c 153 SMART SM00881 17 118 1.3E-25 T 29-03-2018 IPR003781 CoA-binding GO:0048037 CDC59_RS00870 400e8395c6723467ace26c132e763b7c 153 Pfam PF13380 CoA binding domain 21 144 4.1E-40 T 29-03-2018 IPR003781 CoA-binding GO:0048037 CDC59_RS00870 400e8395c6723467ace26c132e763b7c 153 Gene3D G3DSA:3.40.50.720 18 147 6.4E-34 T 29-03-2018 CDC59_RS07305 9a2d399673f388a85fa6f3a6f6a3e03f 309 SUPERFAMILY SSF55048 126 195 9.16E-18 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CDC59_RS07305 9a2d399673f388a85fa6f3a6f6a3e03f 309 SUPERFAMILY SSF52151 196 289 1.92E-70 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CDC59_RS07305 9a2d399673f388a85fa6f3a6f6a3e03f 309 SUPERFAMILY SSF52151 3 126 1.92E-70 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CDC59_RS07305 9a2d399673f388a85fa6f3a6f6a3e03f 309 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 1 288 1.9E-105 T 29-03-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 CDC59_RS07305 9a2d399673f388a85fa6f3a6f6a3e03f 309 PIRSF PIRSF000446 1 309 1.9E-109 T 29-03-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 CDC59_RS07305 9a2d399673f388a85fa6f3a6f6a3e03f 309 Gene3D G3DSA:3.40.366.10 184 309 1.4E-30 T 29-03-2018 CDC59_RS07305 9a2d399673f388a85fa6f3a6f6a3e03f 309 Gene3D G3DSA:3.30.70.250 141 183 7.5E-21 T 29-03-2018 CDC59_RS07305 9a2d399673f388a85fa6f3a6f6a3e03f 309 Pfam PF00698 Acyl transferase domain 5 275 4.0E-36 T 29-03-2018 IPR014043 Acyl transferase CDC59_RS07305 9a2d399673f388a85fa6f3a6f6a3e03f 309 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 6 309 1.0E-36 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CDC59_RS07305 9a2d399673f388a85fa6f3a6f6a3e03f 309 Gene3D G3DSA:3.40.366.10 2 140 2.1E-37 T 29-03-2018 CDC59_RS08210 8804006b9b5812943eb347fdad2e3936 386 TIGRFAM TIGR00443 hisZ_biosyn_reg: ATP phosphoribosyltransferase, regulatory subunit 12 314 1.2E-86 T 29-03-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 CDC59_RS08210 8804006b9b5812943eb347fdad2e3936 386 Pfam PF13393 Histidyl-tRNA synthetase 10 313 3.4E-122 T 29-03-2018 CDC59_RS08210 8804006b9b5812943eb347fdad2e3936 386 Gene3D G3DSA:3.30.930.10 16 305 1.4E-45 T 29-03-2018 CDC59_RS08210 8804006b9b5812943eb347fdad2e3936 386 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 16 364 36.937 T 29-03-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 CDC59_RS08210 8804006b9b5812943eb347fdad2e3936 386 PIRSF PIRSF001549 5 329 2.1E-40 T 29-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 CDC59_RS08210 8804006b9b5812943eb347fdad2e3936 386 SUPERFAMILY SSF55681 4 310 9.05E-59 T 29-03-2018 CDC59_RS13200 d152efb6e8fdb5f998571596f293c508 493 SUPERFAMILY SSF46785 16 87 2.58E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS13200 d152efb6e8fdb5f998571596f293c508 493 Gene3D G3DSA:1.10.10.10 5 85 6.4E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS13200 d152efb6e8fdb5f998571596f293c508 493 Pfam PF00155 Aminotransferase class I and II 163 480 8.5E-32 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CDC59_RS13200 d152efb6e8fdb5f998571596f293c508 493 SUPERFAMILY SSF53383 125 487 6.32E-88 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS13200 d152efb6e8fdb5f998571596f293c508 493 Gene3D G3DSA:3.90.1150.10 394 491 6.0E-24 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS13200 d152efb6e8fdb5f998571596f293c508 493 Gene3D G3DSA:3.40.640.10 142 393 8.4E-51 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDC59_RS13200 d152efb6e8fdb5f998571596f293c508 493 SMART SM00345 24 83 1.6E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDC59_RS13200 d152efb6e8fdb5f998571596f293c508 493 Pfam PF00392 Bacterial regulatory proteins, gntR family 24 83 2.2E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDC59_RS01175 70eb2dfcff95f938afaeaf0f34fea71e 298 SUPERFAMILY SSF103481 41 134 7.19E-10 T 29-03-2018 CDC59_RS01175 70eb2dfcff95f938afaeaf0f34fea71e 298 Pfam PF00892 EamA-like transporter family 148 286 1.3E-16 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CDC59_RS01175 70eb2dfcff95f938afaeaf0f34fea71e 298 Pfam PF00892 EamA-like transporter family 6 131 3.8E-13 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CDC59_RS01175 70eb2dfcff95f938afaeaf0f34fea71e 298 SUPERFAMILY SSF103481 215 290 1.1E-10 T 29-03-2018 CDC59_RS12610 bd611ea1f0ea6f8069ce5e74df238c92 189 Pfam PF13091 PLD-like domain 52 177 3.6E-20 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CDC59_RS12610 bd611ea1f0ea6f8069ce5e74df238c92 189 Gene3D G3DSA:3.30.870.10 37 186 5.1E-21 T 29-03-2018 CDC59_RS12610 bd611ea1f0ea6f8069ce5e74df238c92 189 SUPERFAMILY SSF56024 40 185 2.92E-27 T 29-03-2018 CDC59_RS02410 c96733710e63a061fd03836eaa12cb63 145 PIRSF PIRSF029720 10 145 1.5E-51 T 29-03-2018 IPR014558 Uncharacterised conserved lipoprotein CDC59_RS02410 c96733710e63a061fd03836eaa12cb63 145 Pfam PF03640 Secreted repeat of unknown function 101 144 3.4E-19 T 29-03-2018 IPR005297 Lipoprotein repeat CDC59_RS02410 c96733710e63a061fd03836eaa12cb63 145 Pfam PF03640 Secreted repeat of unknown function 47 88 1.4E-14 T 29-03-2018 IPR005297 Lipoprotein repeat CDC59_RS13845 03845f9c76d9a274a68194e6de11d498 242 SUPERFAMILY SSF161098 23 219 1.7E-41 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS13845 03845f9c76d9a274a68194e6de11d498 242 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 43 234 2.0E-25 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS13845 03845f9c76d9a274a68194e6de11d498 242 Gene3D G3DSA:1.10.3720.10 17 234 2.3E-43 T 29-03-2018 CDC59_RS13845 03845f9c76d9a274a68194e6de11d498 242 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 23 120 4.2E-19 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CDC59_RS19480 99120c77d687d18efc618112403065e6 398 SUPERFAMILY SSF48264 9 398 1.83E-89 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CDC59_RS19480 99120c77d687d18efc618112403065e6 398 PRINTS PR00359 B-class P450 signature 339 348 6.4E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CDC59_RS19480 99120c77d687d18efc618112403065e6 398 PRINTS PR00359 B-class P450 signature 85 96 6.4E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CDC59_RS19480 99120c77d687d18efc618112403065e6 398 PRINTS PR00359 B-class P450 signature 290 317 6.4E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CDC59_RS19480 99120c77d687d18efc618112403065e6 398 PRINTS PR00359 B-class P450 signature 348 359 6.4E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CDC59_RS19480 99120c77d687d18efc618112403065e6 398 PRINTS PR00359 B-class P450 signature 192 214 6.4E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CDC59_RS19480 99120c77d687d18efc618112403065e6 398 PRINTS PR00359 B-class P450 signature 131 147 6.4E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CDC59_RS19480 99120c77d687d18efc618112403065e6 398 PRINTS PR00359 B-class P450 signature 273 284 6.4E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CDC59_RS19480 99120c77d687d18efc618112403065e6 398 PRINTS PR00359 B-class P450 signature 318 333 6.4E-44 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CDC59_RS19480 99120c77d687d18efc618112403065e6 398 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 341 350 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CDC59_RS19480 99120c77d687d18efc618112403065e6 398 Pfam PF00067 Cytochrome P450 274 367 1.7E-15 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CDC59_RS19480 99120c77d687d18efc618112403065e6 398 Pfam PF00067 Cytochrome P450 83 260 1.8E-13 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CDC59_RS19480 99120c77d687d18efc618112403065e6 398 Gene3D G3DSA:1.10.630.10 3 398 2.9E-74 T 29-03-2018 CDC59_RS05610 fbbda89c5203d82c1ccad216f42e20e1 887 Pfam PF02384 N-6 DNA Methylase 343 500 2.2E-5 T 29-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 CDC59_RS05610 fbbda89c5203d82c1ccad216f42e20e1 887 Gene3D G3DSA:3.40.50.150 296 759 1.1E-23 T 29-03-2018 CDC59_RS05610 fbbda89c5203d82c1ccad216f42e20e1 887 SUPERFAMILY SSF53335 150 584 6.66E-48 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS06200 05af26fd25bd2bf506749e69ef968aa9 190 SUPERFAMILY SSF52218 1 184 4.46E-46 T 29-03-2018 IPR029039 Flavoprotein-like domain CDC59_RS06200 05af26fd25bd2bf506749e69ef968aa9 190 Gene3D G3DSA:3.40.50.360 1 190 5.5E-36 T 29-03-2018 IPR029039 Flavoprotein-like domain CDC59_RS06200 05af26fd25bd2bf506749e69ef968aa9 190 ProSitePatterns PS00201 Flavodoxin signature. 6 22 - T 29-03-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 CDC59_RS06200 05af26fd25bd2bf506749e69ef968aa9 190 Pfam PF12724 Flavodoxin domain 6 77 6.0E-10 T 29-03-2018 IPR026816 Flavodoxin domain CDC59_RS15635 2bd810819369b1c137ce5e4c5dce0a7f 304 Pfam PF08543 Phosphomethylpyrimidine kinase 27 281 2.8E-90 T 29-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 CDC59_RS15635 2bd810819369b1c137ce5e4c5dce0a7f 304 SUPERFAMILY SSF53613 17 284 9.98E-77 T 29-03-2018 IPR029056 Ribokinase-like CDC59_RS15635 2bd810819369b1c137ce5e4c5dce0a7f 304 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 20 282 1.9E-91 T 29-03-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CDC59_RS15635 2bd810819369b1c137ce5e4c5dce0a7f 304 Gene3D G3DSA:3.40.1190.20 14 281 1.2E-61 T 29-03-2018 IPR029056 Ribokinase-like CDC59_RS11880 0c8befd1ae7f096b344c2dfeca2c4279 163 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 1 157 1.9E-63 T 29-03-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CDC59_RS11880 0c8befd1ae7f096b344c2dfeca2c4279 163 Gene3D G3DSA:3.30.70.1150 88 159 1.2E-25 T 29-03-2018 CDC59_RS11880 0c8befd1ae7f096b344c2dfeca2c4279 163 Pfam PF10369 Small subunit of acetolactate synthase 84 157 8.6E-26 T 29-03-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CDC59_RS11880 0c8befd1ae7f096b344c2dfeca2c4279 163 Pfam PF13710 ACT domain 12 73 2.0E-15 T 29-03-2018 CDC59_RS11880 0c8befd1ae7f096b344c2dfeca2c4279 163 Gene3D G3DSA:3.30.70.260 1 87 1.2E-24 T 29-03-2018 CDC59_RS11880 0c8befd1ae7f096b344c2dfeca2c4279 163 SUPERFAMILY SSF55021 79 162 3.36E-25 T 29-03-2018 CDC59_RS11880 0c8befd1ae7f096b344c2dfeca2c4279 163 SUPERFAMILY SSF55021 1 76 2.37E-22 T 29-03-2018 CDC59_RS11880 0c8befd1ae7f096b344c2dfeca2c4279 163 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 76 6.0E-37 T 29-03-2018 CDC59_RS13030 0e6619f67a4fd5088d98e79b2c15ca08 354 Pfam PF00881 Nitroreductase family 142 330 1.9E-19 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CDC59_RS13030 0e6619f67a4fd5088d98e79b2c15ca08 354 TIGRFAM TIGR03605 antibiot_sagB: SagB-type dehydrogenase domain 156 329 1.6E-35 T 29-03-2018 IPR020051 SagB-type dehydrogenase domain CDC59_RS13030 0e6619f67a4fd5088d98e79b2c15ca08 354 SUPERFAMILY SSF55469 137 207 1.29E-20 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CDC59_RS13030 0e6619f67a4fd5088d98e79b2c15ca08 354 SUPERFAMILY SSF55469 235 327 1.29E-20 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CDC59_RS13030 0e6619f67a4fd5088d98e79b2c15ca08 354 Gene3D G3DSA:3.40.109.10 101 329 4.4E-38 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CDC59_RS14345 814d8212e0e540382f7740567b356c10 497 Gene3D G3DSA:3.30.830.10 55 278 1.8E-62 T 29-03-2018 CDC59_RS14345 814d8212e0e540382f7740567b356c10 497 Pfam PF05193 Peptidase M16 inactive domain 225 407 6.7E-27 T 29-03-2018 IPR007863 Peptidase M16, C-terminal CDC59_RS14345 814d8212e0e540382f7740567b356c10 497 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 91 114 - T 29-03-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 CDC59_RS14345 814d8212e0e540382f7740567b356c10 497 SUPERFAMILY SSF63411 285 475 1.75E-35 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CDC59_RS14345 814d8212e0e540382f7740567b356c10 497 Gene3D G3DSA:3.30.830.10 286 486 2.4E-37 T 29-03-2018 CDC59_RS14345 814d8212e0e540382f7740567b356c10 497 Pfam PF00675 Insulinase (Peptidase family M16) 72 216 1.1E-25 T 29-03-2018 IPR011765 Peptidase M16, N-terminal CDC59_RS14345 814d8212e0e540382f7740567b356c10 497 SUPERFAMILY SSF63411 58 269 3.48E-59 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CDC59_RS04440 0c5c8eac3eeb707dfa2ef84dfea7d2d4 174 SUPERFAMILY SSF53271 13 153 8.52E-34 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CDC59_RS04440 0c5c8eac3eeb707dfa2ef84dfea7d2d4 174 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 3 169 27.595 T 29-03-2018 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CDC59_RS04440 0c5c8eac3eeb707dfa2ef84dfea7d2d4 174 Gene3D G3DSA:3.40.50.2020 2 158 2.8E-24 T 29-03-2018 CDC59_RS04440 0c5c8eac3eeb707dfa2ef84dfea7d2d4 174 Pfam PF00156 Phosphoribosyl transferase domain 22 135 3.9E-16 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CDC59_RS14410 3bda12d78fd12ec17c394225b290ca54 306 TIGRFAM TIGR02392 rpoH_proteo: alternative sigma factor RpoH 31 303 1.2E-124 T 29-03-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0008270|GO:0009408|GO:0016987 CDC59_RS14410 3bda12d78fd12ec17c394225b290ca54 306 Pfam PF00140 Sigma-70 factor, region 1.2 33 56 6.7E-7 T 29-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS14410 3bda12d78fd12ec17c394225b290ca54 306 SUPERFAMILY SSF88946 31 139 8.9E-43 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS14410 3bda12d78fd12ec17c394225b290ca54 306 Gene3D G3DSA:1.10.601.10 20 139 3.3E-38 T 29-03-2018 CDC59_RS14410 3bda12d78fd12ec17c394225b290ca54 306 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 94 107 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS14410 3bda12d78fd12ec17c394225b290ca54 306 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 65 301 1.4E-32 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS14410 3bda12d78fd12ec17c394225b290ca54 306 Gene3D G3DSA:1.10.10.10 238 305 7.9E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS14410 3bda12d78fd12ec17c394225b290ca54 306 Pfam PF04542 Sigma-70 region 2 70 139 5.8E-19 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS14410 3bda12d78fd12ec17c394225b290ca54 306 SUPERFAMILY SSF88659 207 303 3.92E-15 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS14410 3bda12d78fd12ec17c394225b290ca54 306 Hamap MF_00961 RNA polymerase sigma factor RpoH [rpoH]. 18 304 51.623 T 29-03-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0008270|GO:0009408|GO:0016987 CDC59_RS14410 3bda12d78fd12ec17c394225b290ca54 306 PRINTS PR00046 Major sigma-70 factor signature 272 287 2.1E-16 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS14410 3bda12d78fd12ec17c394225b290ca54 306 PRINTS PR00046 Major sigma-70 factor signature 118 126 2.1E-16 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS14410 3bda12d78fd12ec17c394225b290ca54 306 PRINTS PR00046 Major sigma-70 factor signature 287 298 2.1E-16 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS14410 3bda12d78fd12ec17c394225b290ca54 306 PRINTS PR00046 Major sigma-70 factor signature 94 107 2.1E-16 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS14410 3bda12d78fd12ec17c394225b290ca54 306 Pfam PF04545 Sigma-70, region 4 244 299 9.5E-15 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS14410 3bda12d78fd12ec17c394225b290ca54 306 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 272 298 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CDC59_RS17525 2e5671fab014e175fbffd00eaba57dfb 392 Pfam PF07478 D-ala D-ala ligase C-terminus 186 379 2.8E-9 T 29-03-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDC59_RS17525 2e5671fab014e175fbffd00eaba57dfb 392 Gene3D G3DSA:3.30.470.20 242 388 2.0E-12 T 29-03-2018 CDC59_RS17525 2e5671fab014e175fbffd00eaba57dfb 392 Gene3D G3DSA:3.30.1490.20 143 241 1.6E-11 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CDC59_RS17525 2e5671fab014e175fbffd00eaba57dfb 392 SUPERFAMILY SSF56059 143 380 1.64E-21 T 29-03-2018 CDC59_RS15855 0be63ce268cc420ffc9e70d641294618 334 Pfam PF01738 Dienelactone hydrolase family 97 329 4.6E-16 T 29-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 CDC59_RS15855 0be63ce268cc420ffc9e70d641294618 334 Gene3D G3DSA:3.40.50.1820 23 331 2.3E-29 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS15855 0be63ce268cc420ffc9e70d641294618 334 SUPERFAMILY SSF53474 76 330 1.8E-30 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS09585 4d45346189ede47607019e1298f5d61f 261 SUPERFAMILY SSF51735 9 258 1.06E-63 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS09585 4d45346189ede47607019e1298f5d61f 261 Gene3D G3DSA:3.40.50.720 45 260 3.2E-45 T 29-03-2018 CDC59_RS09585 4d45346189ede47607019e1298f5d61f 261 Gene3D G3DSA:3.40.50.720 2 44 3.6E-7 T 29-03-2018 CDC59_RS09585 4d45346189ede47607019e1298f5d61f 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 1.5E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS09585 4d45346189ede47607019e1298f5d61f 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 223 243 1.5E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS09585 4d45346189ede47607019e1298f5d61f 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.5E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS09585 4d45346189ede47607019e1298f5d61f 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 1.5E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS09585 4d45346189ede47607019e1298f5d61f 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 1.5E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS09585 4d45346189ede47607019e1298f5d61f 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.5E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS09585 4d45346189ede47607019e1298f5d61f 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CDC59_RS09585 4d45346189ede47607019e1298f5d61f 261 Pfam PF00106 short chain dehydrogenase 10 192 6.1E-48 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS09585 4d45346189ede47607019e1298f5d61f 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 2.0E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS09585 4d45346189ede47607019e1298f5d61f 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 2.0E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS09585 4d45346189ede47607019e1298f5d61f 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 2.0E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS16110 8053332e6c8fc322613f79b57dad7564 567 SUPERFAMILY SSF52047 195 400 2.51E-38 T 29-03-2018 CDC59_RS16110 8053332e6c8fc322613f79b57dad7564 567 Gene3D G3DSA:3.80.10.10 349 408 5.5E-9 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like CDC59_RS16110 8053332e6c8fc322613f79b57dad7564 567 Gene3D G3DSA:3.80.10.10 467 539 2.1E-8 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like CDC59_RS16110 8053332e6c8fc322613f79b57dad7564 567 SMART SM00368 362 391 21.0 T 29-03-2018 CDC59_RS16110 8053332e6c8fc322613f79b57dad7564 567 SMART SM00368 413 439 180.0 T 29-03-2018 CDC59_RS16110 8053332e6c8fc322613f79b57dad7564 567 SMART SM00368 242 265 24.0 T 29-03-2018 CDC59_RS16110 8053332e6c8fc322613f79b57dad7564 567 SMART SM00368 266 295 8.6 T 29-03-2018 CDC59_RS16110 8053332e6c8fc322613f79b57dad7564 567 SMART SM00368 461 490 21.0 T 29-03-2018 CDC59_RS16110 8053332e6c8fc322613f79b57dad7564 567 SMART SM00368 314 343 11.0 T 29-03-2018 CDC59_RS16110 8053332e6c8fc322613f79b57dad7564 567 Pfam PF13516 Leucine Rich repeat 461 483 0.42 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS16110 8053332e6c8fc322613f79b57dad7564 567 Pfam PF13516 Leucine Rich repeat 314 336 0.0013 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS16110 8053332e6c8fc322613f79b57dad7564 567 Pfam PF13516 Leucine Rich repeat 224 240 0.6 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS16110 8053332e6c8fc322613f79b57dad7564 567 Pfam PF13516 Leucine Rich repeat 242 264 2.5E-4 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS16110 8053332e6c8fc322613f79b57dad7564 567 Pfam PF13516 Leucine Rich repeat 338 359 9.8E-4 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS16110 8053332e6c8fc322613f79b57dad7564 567 Pfam PF13516 Leucine Rich repeat 362 383 0.073 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS16110 8053332e6c8fc322613f79b57dad7564 567 Pfam PF13516 Leucine Rich repeat 289 312 0.06 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS16110 8053332e6c8fc322613f79b57dad7564 567 Pfam PF13516 Leucine Rich repeat 266 281 1.6 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS16110 8053332e6c8fc322613f79b57dad7564 567 Pfam PF13516 Leucine Rich repeat 509 524 0.038 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 CDC59_RS16110 8053332e6c8fc322613f79b57dad7564 567 Gene3D G3DSA:3.80.10.10 160 348 6.3E-31 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like CDC59_RS16110 8053332e6c8fc322613f79b57dad7564 567 Gene3D G3DSA:3.40.50.2000 409 466 9.4E-8 T 29-03-2018 CDC59_RS16110 8053332e6c8fc322613f79b57dad7564 567 SUPERFAMILY SSF52047 339 536 7.77E-32 T 29-03-2018 CDC59_RS12200 55a2952cfbc96853dfa3e0fcf453ffc3 291 Gene3D G3DSA:3.10.20.10 35 91 1.5E-12 T 29-03-2018 CDC59_RS12200 55a2952cfbc96853dfa3e0fcf453ffc3 291 Pfam PF02634 FdhD/NarQ family 34 267 2.2E-79 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CDC59_RS12200 55a2952cfbc96853dfa3e0fcf453ffc3 291 Gene3D G3DSA:3.40.140.10 133 272 5.9E-51 T 29-03-2018 CDC59_RS12200 55a2952cfbc96853dfa3e0fcf453ffc3 291 SUPERFAMILY SSF53927 18 268 5.72E-71 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CDC59_RS12200 55a2952cfbc96853dfa3e0fcf453ffc3 291 Hamap MF_00187 Sulfurtransferase FdhD [fdhD]. 12 268 27.772 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CDC59_RS12200 55a2952cfbc96853dfa3e0fcf453ffc3 291 PIRSF PIRSF015626 6 272 7.0E-79 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CDC59_RS14500 c4f91a036844a7c9b2185dac8967a44e 85 TIGRFAM TIGR02181 GRX_bact: glutaredoxin 3 4 83 2.1E-33 T 29-03-2018 IPR011900 Glutaredoxin, GrxC GO:0045454 CDC59_RS14500 c4f91a036844a7c9b2185dac8967a44e 85 Pfam PF00462 Glutaredoxin 4 64 8.2E-20 T 29-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 CDC59_RS14500 c4f91a036844a7c9b2185dac8967a44e 85 Gene3D G3DSA:3.40.30.10 1 85 5.9E-26 T 29-03-2018 CDC59_RS14500 c4f91a036844a7c9b2185dac8967a44e 85 ProSitePatterns PS00195 Glutaredoxin active site. 6 22 - T 29-03-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 CDC59_RS14500 c4f91a036844a7c9b2185dac8967a44e 85 SUPERFAMILY SSF52833 1 84 7.9E-25 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS14500 c4f91a036844a7c9b2185dac8967a44e 85 PRINTS PR00160 Glutaredoxin signature 61 74 5.0E-14 T 29-03-2018 IPR014025 Glutaredoxin subgroup CDC59_RS14500 c4f91a036844a7c9b2185dac8967a44e 85 PRINTS PR00160 Glutaredoxin signature 4 22 5.0E-14 T 29-03-2018 IPR014025 Glutaredoxin subgroup CDC59_RS14500 c4f91a036844a7c9b2185dac8967a44e 85 PRINTS PR00160 Glutaredoxin signature 47 60 5.0E-14 T 29-03-2018 IPR014025 Glutaredoxin subgroup CDC59_RS10685 d2c0668cca523deb75d8a789e6cc7e13 809 SUPERFAMILY SSF54991 701 808 1.24E-20 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CDC59_RS10685 d2c0668cca523deb75d8a789e6cc7e13 809 SMART SM00896 706 808 8.3E-32 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CDC59_RS10685 d2c0668cca523deb75d8a789e6cc7e13 809 Gene3D G3DSA:3.30.930.10 492 695 3.9E-41 T 29-03-2018 CDC59_RS10685 d2c0668cca523deb75d8a789e6cc7e13 809 Gene3D G3DSA:3.30.56.10 1 54 1.4E-13 T 29-03-2018 CDC59_RS10685 d2c0668cca523deb75d8a789e6cc7e13 809 SMART SM00873 217 390 1.5E-77 T 29-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CDC59_RS10685 d2c0668cca523deb75d8a789e6cc7e13 809 Pfam PF03484 tRNA synthetase B5 domain 409 474 2.3E-17 T 29-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CDC59_RS10685 d2c0668cca523deb75d8a789e6cc7e13 809 Pfam PF03147 Ferredoxin-fold anticodon binding domain 706 808 3.7E-22 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CDC59_RS10685 d2c0668cca523deb75d8a789e6cc7e13 809 Pfam PF03483 B3/4 domain 218 390 1.6E-59 T 29-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CDC59_RS10685 d2c0668cca523deb75d8a789e6cc7e13 809 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 802 43.458 T 29-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CDC59_RS10685 d2c0668cca523deb75d8a789e6cc7e13 809 Gene3D G3DSA:3.30.56.10 404 478 1.3E-21 T 29-03-2018 CDC59_RS10685 d2c0668cca523deb75d8a789e6cc7e13 809 SUPERFAMILY SSF56037 200 396 3.4E-67 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CDC59_RS10685 d2c0668cca523deb75d8a789e6cc7e13 809 SUPERFAMILY SSF46955 408 478 1.74E-17 T 29-03-2018 IPR009061 Putative DNA-binding domain CDC59_RS10685 d2c0668cca523deb75d8a789e6cc7e13 809 SUPERFAMILY SSF50249 35 202 8.28E-51 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDC59_RS10685 d2c0668cca523deb75d8a789e6cc7e13 809 SUPERFAMILY SSF55681 470 695 1.04E-52 T 29-03-2018 CDC59_RS10685 d2c0668cca523deb75d8a789e6cc7e13 809 Gene3D G3DSA:3.30.70.380 702 808 3.0E-20 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CDC59_RS10685 d2c0668cca523deb75d8a789e6cc7e13 809 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 808 1.7E-225 T 29-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CDC59_RS10685 d2c0668cca523deb75d8a789e6cc7e13 809 Gene3D G3DSA:2.40.50.140 55 159 7.2E-42 T 29-03-2018 CDC59_RS10685 d2c0668cca523deb75d8a789e6cc7e13 809 Gene3D G3DSA:3.50.40.10 200 397 4.5E-65 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CDC59_RS10685 d2c0668cca523deb75d8a789e6cc7e13 809 SMART SM00874 406 474 4.7E-26 T 29-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CDC59_RS10685 d2c0668cca523deb75d8a789e6cc7e13 809 Pfam PF01588 Putative tRNA binding domain 45 150 5.5E-24 T 29-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 CDC59_RS16045 e3c469f4bb2d37cea422a7b7640a3e57 289 Gene3D G3DSA:3.40.190.10 86 172 7.6E-14 T 29-03-2018 CDC59_RS16045 e3c469f4bb2d37cea422a7b7640a3e57 289 Pfam PF03466 LysR substrate binding domain 86 275 1.6E-29 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS16045 e3c469f4bb2d37cea422a7b7640a3e57 289 SUPERFAMILY SSF46785 2 109 2.07E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS16045 e3c469f4bb2d37cea422a7b7640a3e57 289 Gene3D G3DSA:3.40.190.10 173 238 2.1E-6 T 29-03-2018 CDC59_RS16045 e3c469f4bb2d37cea422a7b7640a3e57 289 SUPERFAMILY SSF53850 88 281 3.26E-34 T 29-03-2018 CDC59_RS16045 e3c469f4bb2d37cea422a7b7640a3e57 289 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 3.8E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS16045 e3c469f4bb2d37cea422a7b7640a3e57 289 Gene3D G3DSA:1.10.10.10 1 83 5.2E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS05875 7682b39f2d2a8ba23fe351cb59e5b83a 154 Pfam PF02627 Carboxymuconolactone decarboxylase family 48 133 5.7E-20 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CDC59_RS05875 7682b39f2d2a8ba23fe351cb59e5b83a 154 Gene3D G3DSA:1.20.1290.10 20 154 5.2E-34 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CDC59_RS05875 7682b39f2d2a8ba23fe351cb59e5b83a 154 SUPERFAMILY SSF69118 12 139 3.36E-33 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CDC59_RS03635 374cd5c448dc46b0678864d77b861bea 106 Pfam PF12769 4TM region of pyridine nucleotide transhydrogenase, mitoch 11 94 1.4E-35 T 29-03-2018 IPR024605 NAD(P) transhydrogenase, alpha subunit, C-terminal KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 CDC59_RS08430 c4332ffc6f2d0a7c57fee0c13ba6a8f1 295 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 41 249 5.0E-39 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CDC59_RS08430 c4332ffc6f2d0a7c57fee0c13ba6a8f1 295 Gene3D G3DSA:3.40.50.1000 25 288 1.4E-22 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS08430 c4332ffc6f2d0a7c57fee0c13ba6a8f1 295 SUPERFAMILY SSF56784 41 282 6.28E-29 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS08430 c4332ffc6f2d0a7c57fee0c13ba6a8f1 295 Pfam PF08282 haloacid dehalogenase-like hydrolase 41 104 1.4E-8 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS20005 41cf9f9e6008c8630f7ba2fa458c2b6a 311 Pfam PF00701 Dihydrodipicolinate synthetase family 15 301 1.1E-52 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CDC59_RS20005 41cf9f9e6008c8630f7ba2fa458c2b6a 311 TIGRFAM TIGR03249 KdgD: 5-dehydro-4-deoxyglucarate dehydratase 6 302 2.0E-131 T 29-03-2018 IPR017655 5-dehydro-4-deoxyglucarate dehydratase GO:0016052|GO:0047448 KEGG: 00053+4.2.1.41|MetaCyc: PWY-6486|MetaCyc: PWY-6497|MetaCyc: PWY-6499|MetaCyc: PWY-6501 CDC59_RS20005 41cf9f9e6008c8630f7ba2fa458c2b6a 311 SUPERFAMILY SSF51569 16 302 9.21E-68 T 29-03-2018 CDC59_RS20005 41cf9f9e6008c8630f7ba2fa458c2b6a 311 Gene3D G3DSA:3.20.20.70 2 307 2.5E-69 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS20005 41cf9f9e6008c8630f7ba2fa458c2b6a 311 Hamap MF_00694 Probable 5-dehydro-4-deoxyglucarate dehydratase. 13 304 44.182 T 29-03-2018 IPR017655 5-dehydro-4-deoxyglucarate dehydratase GO:0016052|GO:0047448 KEGG: 00053+4.2.1.41|MetaCyc: PWY-6486|MetaCyc: PWY-6497|MetaCyc: PWY-6499|MetaCyc: PWY-6501 CDC59_RS20005 41cf9f9e6008c8630f7ba2fa458c2b6a 311 PIRSF PIRSF001365 12 310 4.7E-58 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CDC59_RS20005 41cf9f9e6008c8630f7ba2fa458c2b6a 311 SMART SM01130 13 304 1.2E-70 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CDC59_RS08830 9255519f0155007fa4889d42112459be 390 SUPERFAMILY SSF51679 1 357 1.01E-94 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CDC59_RS08830 9255519f0155007fa4889d42112459be 390 Pfam PF00296 Luciferase-like monooxygenase 1 331 2.6E-86 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CDC59_RS08830 9255519f0155007fa4889d42112459be 390 Gene3D G3DSA:3.20.20.30 1 365 1.7E-90 T 29-03-2018 CDC59_RS08830 9255519f0155007fa4889d42112459be 390 Hamap MF_01229 Alkanesulfonate monooxygenase [ssuD]. 2 388 69.568 T 29-03-2018 IPR019911 Alkanesulphonate monooxygenase, FMN-dependent GO:0008726|GO:0055114 KEGG: 00920+1.14.14.5 CDC59_RS08830 9255519f0155007fa4889d42112459be 390 TIGRFAM TIGR03565 alk_sulf_monoox: alkanesulfonate monooxygenase, FMNH(2)-dependent 2 355 1.2E-189 T 29-03-2018 IPR019911 Alkanesulphonate monooxygenase, FMN-dependent GO:0008726|GO:0055114 KEGG: 00920+1.14.14.5 CDC59_RS11155 5c250e91f1cee594b990ee663cafbe0f 383 Pfam PF13458 Periplasmic binding protein 38 373 8.4E-47 T 29-03-2018 IPR028081 Leucine-binding protein domain CDC59_RS11155 5c250e91f1cee594b990ee663cafbe0f 383 Gene3D G3DSA:3.40.50.2300 212 371 2.8E-15 T 29-03-2018 CDC59_RS11155 5c250e91f1cee594b990ee663cafbe0f 383 SUPERFAMILY SSF53822 38 382 1.2E-57 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CDC59_RS11155 5c250e91f1cee594b990ee663cafbe0f 383 Gene3D G3DSA:3.40.50.2300 33 206 6.7E-23 T 29-03-2018 CDC59_RS01065 3acbadc66f95a8f630d31c15133c4645 260 Gene3D G3DSA:3.20.20.150 1 259 1.9E-54 T 29-03-2018 CDC59_RS01065 3acbadc66f95a8f630d31c15133c4645 260 TIGRFAM TIGR03234 OH-pyruv-isom: hydroxypyruvate isomerase 2 253 4.5E-112 T 29-03-2018 IPR017643 Hydroxypyruvate isomerase KEGG: 00630+5.3.1.22 CDC59_RS01065 3acbadc66f95a8f630d31c15133c4645 260 Pfam PF01261 Xylose isomerase-like TIM barrel 21 219 9.5E-33 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CDC59_RS01065 3acbadc66f95a8f630d31c15133c4645 260 PIRSF PIRSF006241 1 260 9.0E-92 T 29-03-2018 IPR026040 Hydroxypyruvate isomerase-like KEGG: 00630+5.3.1.22 CDC59_RS01065 3acbadc66f95a8f630d31c15133c4645 260 SUPERFAMILY SSF51658 1 255 4.28E-82 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CDC59_RS16515 eac9109eae8293c3e85b141a605750fa 127 Gene3D G3DSA:3.40.630.30 2 115 5.0E-17 T 29-03-2018 CDC59_RS16515 eac9109eae8293c3e85b141a605750fa 127 Pfam PF00583 Acetyltransferase (GNAT) family 39 101 2.2E-9 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CDC59_RS16515 eac9109eae8293c3e85b141a605750fa 127 SUPERFAMILY SSF55729 8 105 7.77E-17 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDC59_RS09875 aca4f7ba42c898dc7ac06a3c391f4391 282 SUPERFAMILY SSF56300 1 260 3.19E-51 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CDC59_RS09875 aca4f7ba42c898dc7ac06a3c391f4391 282 Hamap MF_00905 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [cpdA]. 1 264 37.45 T 29-03-2018 IPR026575 3,5-cyclic adenosine monophosphate phosphodiesterase CpdA GO:0004115 KEGG: 00230+3.1.4.53 CDC59_RS09875 aca4f7ba42c898dc7ac06a3c391f4391 282 Pfam PF00149 Calcineurin-like phosphoesterase 1 206 3.1E-20 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CDC59_RS09875 aca4f7ba42c898dc7ac06a3c391f4391 282 Gene3D G3DSA:3.60.21.10 1 259 5.0E-44 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CDC59_RS19420 0b3eb4e2acf897d7e004ffdfee44608a 448 Gene3D G3DSA:2.60.120.10 211 250 1.1E-9 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CDC59_RS19420 0b3eb4e2acf897d7e004ffdfee44608a 448 Gene3D G3DSA:2.60.120.10 290 413 1.2E-50 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CDC59_RS19420 0b3eb4e2acf897d7e004ffdfee44608a 448 TIGRFAM TIGR01015 hmgA: homogentisate 1,2-dioxygenase 21 443 5.0E-206 T 29-03-2018 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 CDC59_RS19420 0b3eb4e2acf897d7e004ffdfee44608a 448 Hamap MF_00334 Homogentisate 1,2-dioxygenase [hmgA]. 21 445 73.908 T 29-03-2018 IPR022950 Homogentisate 1,2-dioxygenase, bacterial GO:0004411|GO:0006559|GO:0006572|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5 CDC59_RS19420 0b3eb4e2acf897d7e004ffdfee44608a 448 Pfam PF04209 homogentisate 1,2-dioxygenase 21 443 4.8E-208 T 29-03-2018 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 CDC59_RS19420 0b3eb4e2acf897d7e004ffdfee44608a 448 SUPERFAMILY SSF51182 20 446 6.89E-177 T 29-03-2018 IPR011051 RmlC-like cupin domain CDC59_RS09405 60ffe92ebc3ae39dbdbe7cb5df1ce30b 183 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 23 164 45.443 T 29-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 CDC59_RS09405 60ffe92ebc3ae39dbdbe7cb5df1ce30b 183 Gene3D G3DSA:3.40.140.10 12 173 2.4E-52 T 29-03-2018 CDC59_RS09405 60ffe92ebc3ae39dbdbe7cb5df1ce30b 183 Pfam PF14437 MafB19-like deaminase 21 164 7.2E-28 T 29-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 CDC59_RS09405 60ffe92ebc3ae39dbdbe7cb5df1ce30b 183 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 68 105 - T 29-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CDC59_RS09405 60ffe92ebc3ae39dbdbe7cb5df1ce30b 183 SUPERFAMILY SSF53927 13 165 5.52E-55 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CDC59_RS08780 b32634580668e216019d36b5cf2f403a 419 Gene3D G3DSA:2.40.340.10 346 417 6.5E-11 T 29-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CDC59_RS08780 b32634580668e216019d36b5cf2f403a 419 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 186 331 2.8E-25 T 29-03-2018 IPR001453 MoaB/Mog domain CDC59_RS08780 b32634580668e216019d36b5cf2f403a 419 SUPERFAMILY SSF53218 184 339 1.96E-41 T 29-03-2018 IPR001453 MoaB/Mog domain CDC59_RS08780 b32634580668e216019d36b5cf2f403a 419 ProSitePatterns PS01079 Molybdenum cofactor biosynthesis proteins signature 2. 262 295 - T 29-03-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 CDC59_RS08780 b32634580668e216019d36b5cf2f403a 419 Pfam PF00994 Probable molybdopterin binding domain 189 333 1.3E-25 T 29-03-2018 IPR001453 MoaB/Mog domain CDC59_RS08780 b32634580668e216019d36b5cf2f403a 419 SMART SM00852 189 335 1.6E-45 T 29-03-2018 IPR001453 MoaB/Mog domain CDC59_RS08780 b32634580668e216019d36b5cf2f403a 419 SUPERFAMILY SSF63867 344 417 7.72E-14 T 29-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CDC59_RS08780 b32634580668e216019d36b5cf2f403a 419 Gene3D G3DSA:3.40.980.10 159 345 1.4E-53 T 29-03-2018 IPR001453 MoaB/Mog domain CDC59_RS08780 b32634580668e216019d36b5cf2f403a 419 SUPERFAMILY SSF63882 11 185 4.06E-49 T 29-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CDC59_RS08780 b32634580668e216019d36b5cf2f403a 419 Pfam PF03453 MoeA N-terminal region (domain I and II) 15 176 5.6E-43 T 29-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CDC59_RS08780 b32634580668e216019d36b5cf2f403a 419 Pfam PF03454 MoeA C-terminal region (domain IV) 350 415 2.0E-9 T 29-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CDC59_RS08780 b32634580668e216019d36b5cf2f403a 419 Gene3D G3DSA:3.90.105.10 33 67 2.7E-12 T 29-03-2018 CDC59_RS08780 b32634580668e216019d36b5cf2f403a 419 Gene3D G3DSA:2.170.190.11 68 150 6.9E-26 T 29-03-2018 CDC59_RS11565 60cb72d141390da738d156a64aba6f5f 218 SUPERFAMILY SSF52833 1 95 5.95E-18 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS11565 60cb72d141390da738d156a64aba6f5f 218 Gene3D G3DSA:3.40.30.10 1 83 1.1E-17 T 29-03-2018 CDC59_RS11565 60cb72d141390da738d156a64aba6f5f 218 Pfam PF13417 Glutathione S-transferase, N-terminal domain 4 74 8.3E-16 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CDC59_RS11565 60cb72d141390da738d156a64aba6f5f 218 Gene3D G3DSA:1.20.1050.10 84 212 3.1E-19 T 29-03-2018 CDC59_RS11565 60cb72d141390da738d156a64aba6f5f 218 SUPERFAMILY SSF47616 72 214 1.04E-19 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like CDC59_RS11565 60cb72d141390da738d156a64aba6f5f 218 Pfam PF13410 Glutathione S-transferase, C-terminal domain 120 188 8.9E-8 T 29-03-2018 CDC59_RS09960 c0a7e95927a50c251c5ba2ea343b398e 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS09960 c0a7e95927a50c251c5ba2ea343b398e 328 Pfam PF05598 Transposase domain (DUF772) 51 126 3.1E-23 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS16510 6f5dc2220a86083ca28fc02ed64f23fe 396 Pfam PF01095 Pectinesterase 81 327 6.0E-30 T 29-03-2018 IPR000070 Pectinesterase, catalytic GO:0005618|GO:0030599|GO:0042545 KEGG: 00040+3.1.1.11|MetaCyc: PWY-1081|MetaCyc: PWY-7246|MetaCyc: PWY-7248 CDC59_RS16510 6f5dc2220a86083ca28fc02ed64f23fe 396 SUPERFAMILY SSF51126 74 395 3.4E-53 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CDC59_RS16510 6f5dc2220a86083ca28fc02ed64f23fe 396 ProSitePatterns PS00503 Pectinesterase signature 2. 254 263 - T 29-03-2018 IPR033131 Pectinesterase, Asp active site KEGG: 00040+3.1.1.11|MetaCyc: PWY-1081|MetaCyc: PWY-7246|MetaCyc: PWY-7248 CDC59_RS16510 6f5dc2220a86083ca28fc02ed64f23fe 396 Gene3D G3DSA:2.160.20.10 72 396 3.4E-60 T 29-03-2018 IPR012334 Pectin lyase fold CDC59_RS04605 ddd920fabbb958916e4f2430f98e2231 505 Pfam PF00171 Aldehyde dehydrogenase family 36 498 1.2E-172 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CDC59_RS04605 ddd920fabbb958916e4f2430f98e2231 505 SUPERFAMILY SSF53720 25 502 4.97E-174 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CDC59_RS04605 ddd920fabbb958916e4f2430f98e2231 505 Gene3D G3DSA:3.40.309.10 293 486 4.5E-74 T 29-03-2018 CDC59_RS04605 ddd920fabbb958916e4f2430f98e2231 505 TIGRFAM TIGR01780 SSADH: succinate-semialdehyde dehydrogenase 47 498 1.8E-215 T 29-03-2018 IPR010102 Succinate semialdehyde dehydrogenase GO:0009013|GO:0009450|GO:0055114 Reactome: R-HSA-916853 CDC59_RS04605 ddd920fabbb958916e4f2430f98e2231 505 Gene3D G3DSA:3.40.605.10 23 292 1.4E-102 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CDC59_RS04605 ddd920fabbb958916e4f2430f98e2231 505 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 302 313 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CDC59_RS04005 8b5f25ff3ce1a3e6b0151520ea6b9cd8 206 Gene3D G3DSA:1.20.1540.10 6 196 4.4E-14 T 29-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CDC59_RS04005 8b5f25ff3ce1a3e6b0151520ea6b9cd8 206 Pfam PF01694 Rhomboid family 42 194 1.3E-6 T 29-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CDC59_RS04005 8b5f25ff3ce1a3e6b0151520ea6b9cd8 206 TIGRFAM TIGR03902 rhom_GG_sort: rhombosortase 32 193 1.7E-42 T 29-03-2018 IPR023826 Rhomboid-like serine protease, proteobacteria CDC59_RS04005 8b5f25ff3ce1a3e6b0151520ea6b9cd8 206 SUPERFAMILY SSF144091 10 194 5.1E-20 T 29-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CDC59_RS20095 bdd879e5d1cdbdb87e51909dd6e20d0f 134 Pfam PF01638 HxlR-like helix-turn-helix 30 115 2.3E-27 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type CDC59_RS20095 bdd879e5d1cdbdb87e51909dd6e20d0f 134 Gene3D G3DSA:1.10.10.10 27 126 2.4E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS20095 bdd879e5d1cdbdb87e51909dd6e20d0f 134 SUPERFAMILY SSF46785 22 124 2.63E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS05940 77df65f6d260839b028bc683ab8920ae 231 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 17 121 7.4E-20 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CDC59_RS05940 77df65f6d260839b028bc683ab8920ae 231 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 37 225 7.9E-24 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS05940 77df65f6d260839b028bc683ab8920ae 231 Gene3D G3DSA:1.10.3720.10 4 230 4.6E-47 T 29-03-2018 CDC59_RS05940 77df65f6d260839b028bc683ab8920ae 231 SUPERFAMILY SSF161098 16 212 2.75E-45 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS05220 7ffe3093476a3d3b7716ea6e6ca5b87b 59 TIGRFAM TIGR04111 BcepMu_gp16: phage-associated protein, BcepMu gp16 family 2 56 1.3E-26 T 29-03-2018 IPR026365 Phage-associated protein, BcepMu gp16 family CDC59_RS15380 769815ba7ea7723996e3a5310de033b9 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 18 35 2.2E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS15380 769815ba7ea7723996e3a5310de033b9 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 93 104 2.2E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS15380 769815ba7ea7723996e3a5310de033b9 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 191 2.2E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS15380 769815ba7ea7723996e3a5310de033b9 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 192 209 2.2E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS15380 769815ba7ea7723996e3a5310de033b9 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 223 243 2.2E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS15380 769815ba7ea7723996e3a5310de033b9 271 Gene3D G3DSA:3.40.50.720 7 267 4.3E-48 T 29-03-2018 CDC59_RS15380 769815ba7ea7723996e3a5310de033b9 271 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 23 258 8.9E-33 T 29-03-2018 CDC59_RS15380 769815ba7ea7723996e3a5310de033b9 271 SUPERFAMILY SSF51735 17 260 1.53E-51 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS06545 b4fd10012be31511310b6045e6317184 468 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 19 445 4.4E-119 T 29-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CDC59_RS06545 b4fd10012be31511310b6045e6317184 468 TIGRFAM TIGR03173 pbuX: xanthine permease 25 447 5.3E-163 T 29-03-2018 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 CDC59_RS06545 b4fd10012be31511310b6045e6317184 468 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 362 382 - T 29-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CDC59_RS06545 b4fd10012be31511310b6045e6317184 468 Pfam PF00860 Permease family 22 415 2.2E-101 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CDC59_RS07510 a88283eb0bf55b8b1424848d506c3c38 103 SUPERFAMILY SSF50022 3 103 1.44E-29 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CDC59_RS07510 a88283eb0bf55b8b1424848d506c3c38 103 Gene3D G3DSA:2.102.10.10 1 103 4.8E-26 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CDC59_RS07510 a88283eb0bf55b8b1424848d506c3c38 103 Pfam PF00355 Rieske [2Fe-2S] domain 4 91 3.1E-19 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CDC59_RS01170 588f91edea997a921caab61d2b8c2831 431 Gene3D G3DSA:3.90.760.10 365 431 1.6E-19 T 29-03-2018 IPR015323 Flavocytochrome c sulphide dehydrogenase, flavin-binding GO:0016491|GO:0050660|GO:0055114 KEGG: 00920+1.8.2.3|MetaCyc: PWY-5274 CDC59_RS01170 588f91edea997a921caab61d2b8c2831 431 Pfam PF09242 Flavocytochrome c sulphide dehydrogenase, flavin-binding 364 430 2.4E-21 T 29-03-2018 IPR015323 Flavocytochrome c sulphide dehydrogenase, flavin-binding GO:0016491|GO:0050660|GO:0055114 KEGG: 00920+1.8.2.3|MetaCyc: PWY-5274 CDC59_RS01170 588f91edea997a921caab61d2b8c2831 431 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 39 343 4.0E-12 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS01170 588f91edea997a921caab61d2b8c2831 431 SUPERFAMILY SSF51905 155 287 2.07E-31 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS01170 588f91edea997a921caab61d2b8c2831 431 Gene3D G3DSA:3.50.50.60 155 287 5.0E-22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS01170 588f91edea997a921caab61d2b8c2831 431 SUPERFAMILY SSF55424 363 431 4.94E-20 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CDC59_RS01170 588f91edea997a921caab61d2b8c2831 431 Gene3D G3DSA:3.50.50.60 26 140 5.3E-11 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS01170 588f91edea997a921caab61d2b8c2831 431 SUPERFAMILY SSF51905 282 359 2.26E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS01170 588f91edea997a921caab61d2b8c2831 431 SUPERFAMILY SSF51905 39 145 2.26E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS19005 a12dea176ade5b6fe37364381f8eec8a 90 Pfam PF07007 Lysozyme inhibitor LprI 3 84 4.2E-15 T 29-03-2018 IPR009739 Lysozyme inhibitor LprI, N-terminal CDC59_RS21270 0e7c0ac6818a7cd9e107cb0f3e404467 326 Pfam PF00294 pfkB family carbohydrate kinase 28 313 1.0E-43 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB CDC59_RS21270 0e7c0ac6818a7cd9e107cb0f3e404467 326 Gene3D G3DSA:3.40.1190.20 28 325 3.6E-53 T 29-03-2018 IPR029056 Ribokinase-like CDC59_RS21270 0e7c0ac6818a7cd9e107cb0f3e404467 326 SUPERFAMILY SSF53613 27 321 4.21E-60 T 29-03-2018 IPR029056 Ribokinase-like CDC59_RS08855 8e2650829857b83a9aa4f2864d1ce45e 222 Pfam PF06821 Serine hydrolase 23 192 3.1E-62 T 29-03-2018 IPR010662 Putative hydrolase RBBP9/YdeN GO:0016787 CDC59_RS08855 8e2650829857b83a9aa4f2864d1ce45e 222 SUPERFAMILY SSF53474 22 191 2.34E-31 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS08855 8e2650829857b83a9aa4f2864d1ce45e 222 Gene3D G3DSA:3.40.50.1820 9 200 2.9E-14 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS13335 d5bf49797918538dd5b83214d8cd395f 308 Gene3D G3DSA:3.30.200.20 21 119 4.9E-31 T 29-03-2018 CDC59_RS13335 d5bf49797918538dd5b83214d8cd395f 308 SUPERFAMILY SSF56104 11 306 8.83E-101 T 29-03-2018 CDC59_RS13335 d5bf49797918538dd5b83214d8cd395f 308 Pfam PF01259 SAICAR synthetase 22 269 1.1E-99 T 29-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CDC59_RS13335 d5bf49797918538dd5b83214d8cd395f 308 Gene3D G3DSA:3.30.470.20 120 255 1.0E-54 T 29-03-2018 CDC59_RS13335 d5bf49797918538dd5b83214d8cd395f 308 ProSitePatterns PS01057 SAICAR synthetase signature 1. 112 126 - T 29-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CDC59_RS13335 d5bf49797918538dd5b83214d8cd395f 308 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 22 304 9.1E-77 T 29-03-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 CDC59_RS13335 d5bf49797918538dd5b83214d8cd395f 308 ProSitePatterns PS01058 SAICAR synthetase signature 2. 211 219 - T 29-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CDC59_RS13335 d5bf49797918538dd5b83214d8cd395f 308 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 19 304 25.283 T 29-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CDC59_RS04575 95e889770ea7acbc7ca07ae0ea6041cc 251 SUPERFAMILY SSF53335 28 249 4.82E-47 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS04575 95e889770ea7acbc7ca07ae0ea6041cc 251 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 36 249 30.273 T 29-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CDC59_RS04575 95e889770ea7acbc7ca07ae0ea6041cc 251 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 65 248 4.8E-53 T 29-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CDC59_RS04575 95e889770ea7acbc7ca07ae0ea6041cc 251 Gene3D G3DSA:3.40.50.150 42 251 9.1E-34 T 29-03-2018 CDC59_RS04575 95e889770ea7acbc7ca07ae0ea6041cc 251 Pfam PF02390 Putative methyltransferase 80 243 1.1E-53 T 29-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CDC59_RS07890 dda8d103a0c9bb895ed03e104927ee40 301 SUPERFAMILY SSF48150 125 296 8.55E-44 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CDC59_RS07890 dda8d103a0c9bb895ed03e104927ee40 301 Gene3D G3DSA:1.10.1670.10 246 300 4.0E-15 T 29-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CDC59_RS07890 dda8d103a0c9bb895ed03e104927ee40 301 SMART SM00478 144 296 7.3E-20 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CDC59_RS07890 dda8d103a0c9bb895ed03e104927ee40 301 Gene3D G3DSA:1.10.340.30 132 243 4.8E-28 T 29-03-2018 CDC59_RS07890 dda8d103a0c9bb895ed03e104927ee40 301 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 141 280 2.8E-14 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CDC59_RS07790 5d1a3f9d7ab73465340914203ee47bdb 409 Gene3D G3DSA:2.60.120.650 22 234 6.3E-31 T 29-03-2018 CDC59_RS07790 5d1a3f9d7ab73465340914203ee47bdb 409 Pfam PF08007 Cupin superfamily protein 31 340 1.4E-97 T 29-03-2018 IPR003347 JmjC domain CDC59_RS07790 5d1a3f9d7ab73465340914203ee47bdb 409 SUPERFAMILY SSF51197 22 313 6.18E-74 T 29-03-2018 CDC59_RS07790 5d1a3f9d7ab73465340914203ee47bdb 409 SMART SM00558 82 247 4.4E-4 T 29-03-2018 IPR003347 JmjC domain CDC59_RS19855 ef2a7381a9bafb0f30543468b18e468a 1114 Gene3D G3DSA:1.20.120.20 49 1088 1.4E-4 T 29-03-2018 CDC59_RS20305 72722a0661eb12ee1e7c3ae41de47e19 296 Pfam PF03466 LysR substrate binding domain 87 284 2.8E-17 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS20305 72722a0661eb12ee1e7c3ae41de47e19 296 SUPERFAMILY SSF53850 90 276 1.81E-21 T 29-03-2018 CDC59_RS20305 72722a0661eb12ee1e7c3ae41de47e19 296 SUPERFAMILY SSF46785 2 101 5.17E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS20305 72722a0661eb12ee1e7c3ae41de47e19 296 Gene3D G3DSA:1.10.10.10 1 82 7.9E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS20305 72722a0661eb12ee1e7c3ae41de47e19 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 60 3.9E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS20305 72722a0661eb12ee1e7c3ae41de47e19 296 Gene3D G3DSA:3.40.190.10 181 263 8.6E-9 T 29-03-2018 CDC59_RS20305 72722a0661eb12ee1e7c3ae41de47e19 296 Gene3D G3DSA:3.40.190.10 83 180 9.7E-14 T 29-03-2018 CDC59_RS20305 72722a0661eb12ee1e7c3ae41de47e19 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 7.2E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS20305 72722a0661eb12ee1e7c3ae41de47e19 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 7.2E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS20305 72722a0661eb12ee1e7c3ae41de47e19 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 7.2E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS00090 400a877c05a70aca9b721db19e010239 296 SUPERFAMILY SSF53213 1 283 4.84E-80 T 29-03-2018 CDC59_RS00090 400a877c05a70aca9b721db19e010239 296 Gene3D G3DSA:3.40.830.10 1 283 8.3E-83 T 29-03-2018 CDC59_RS00090 400a877c05a70aca9b721db19e010239 296 PIRSF PIRSF006157 1 284 1.6E-96 T 29-03-2018 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA-type GO:0008270|GO:0016701|GO:0055114 CDC59_RS00090 400a877c05a70aca9b721db19e010239 296 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 4 282 1.2E-73 T 29-03-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 CDC59_RS07065 a855bf0e7a45479c717dbfe4feb1c07d 312 SUPERFAMILY SSF103481 211 301 1.7E-15 T 29-03-2018 CDC59_RS07065 a855bf0e7a45479c717dbfe4feb1c07d 312 SUPERFAMILY SSF103481 55 152 8.63E-15 T 29-03-2018 CDC59_RS07065 a855bf0e7a45479c717dbfe4feb1c07d 312 Pfam PF00892 EamA-like transporter family 163 297 2.8E-22 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CDC59_RS07065 a855bf0e7a45479c717dbfe4feb1c07d 312 Pfam PF00892 EamA-like transporter family 19 152 1.8E-16 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CDC59_RS20330 6678bcb7d2bea000b233b40a65f7877c 310 Gene3D G3DSA:2.170.270.10 159 292 3.2E-9 T 29-03-2018 CDC59_RS20330 6678bcb7d2bea000b233b40a65f7877c 310 SUPERFAMILY SSF82199 235 292 1.49E-7 T 29-03-2018 CDC59_RS20330 6678bcb7d2bea000b233b40a65f7877c 310 SUPERFAMILY SSF82199 169 204 1.49E-7 T 29-03-2018 CDC59_RS01630 4193f983737e5ff3dc2279f379008284 506 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 294 305 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CDC59_RS01630 4193f983737e5ff3dc2279f379008284 506 Gene3D G3DSA:3.40.309.10 281 474 4.2E-61 T 29-03-2018 CDC59_RS01630 4193f983737e5ff3dc2279f379008284 506 Gene3D G3DSA:3.40.605.10 11 280 8.1E-95 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CDC59_RS01630 4193f983737e5ff3dc2279f379008284 506 SUPERFAMILY SSF53720 12 497 1.57E-160 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CDC59_RS01630 4193f983737e5ff3dc2279f379008284 506 Pfam PF00171 Aldehyde dehydrogenase family 34 493 1.3E-164 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CDC59_RS01630 4193f983737e5ff3dc2279f379008284 506 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 261 268 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CDC59_RS13965 04bc19e3deb23edffd445d38431227ea 243 Gene3D G3DSA:3.40.50.150 15 236 7.3E-41 T 29-03-2018 CDC59_RS13965 04bc19e3deb23edffd445d38431227ea 243 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 11 242 35.319 T 29-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CDC59_RS13965 04bc19e3deb23edffd445d38431227ea 243 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 20 241 4.2E-73 T 29-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CDC59_RS13965 04bc19e3deb23edffd445d38431227ea 243 SUPERFAMILY SSF53335 1 233 2.97E-42 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS13965 04bc19e3deb23edffd445d38431227ea 243 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 151 165 - T 29-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 CDC59_RS13965 04bc19e3deb23edffd445d38431227ea 243 Pfam PF01209 ubiE/COQ5 methyltransferase family 16 240 5.6E-85 T 29-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CDC59_RS13965 04bc19e3deb23edffd445d38431227ea 243 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 31 46 - T 29-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 CDC59_RS13865 e4b98d74609c32da28177dac32d0b909 608 Gene3D G3DSA:3.40.50.300 349 602 3.6E-78 T 29-03-2018 CDC59_RS13865 e4b98d74609c32da28177dac32d0b909 608 ProSitePatterns PS00211 ABC transporters family signature. 498 512 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS13865 e4b98d74609c32da28177dac32d0b909 608 SUPERFAMILY SSF90123 25 341 2.62E-66 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CDC59_RS13865 e4b98d74609c32da28177dac32d0b909 608 SUPERFAMILY SSF52540 350 596 3.26E-92 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS13865 e4b98d74609c32da28177dac32d0b909 608 Pfam PF00005 ABC transporter 379 526 4.3E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS13865 e4b98d74609c32da28177dac32d0b909 608 Gene3D G3DSA:1.20.1560.10 18 348 4.7E-60 T 29-03-2018 CDC59_RS13865 e4b98d74609c32da28177dac32d0b909 608 SMART SM00382 386 587 4.7E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS13865 e4b98d74609c32da28177dac32d0b909 608 Pfam PF00664 ABC transporter transmembrane region 40 312 8.1E-43 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CDC59_RS08485 c54a8b10f23edaf0ccc7e24b01024729 281 Pfam PF04029 2-phosphosulpholactate phosphatase 27 241 2.9E-23 T 29-03-2018 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 CDC59_RS08485 c54a8b10f23edaf0ccc7e24b01024729 281 SUPERFAMILY SSF142823 8 244 7.72E-47 T 29-03-2018 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 CDC59_RS08485 c54a8b10f23edaf0ccc7e24b01024729 281 Gene3D G3DSA:3.90.1560.10 15 250 4.2E-62 T 29-03-2018 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 CDC59_RS14135 6de7419039facfac17943832899993fd 85 Gene3D G3DSA:1.10.287.700 19 84 4.3E-4 T 29-03-2018 CDC59_RS00450 7090595235d69b1bf4be32edaf3ce3ba 170 Gene3D G3DSA:1.10.10.10 1 160 4.6E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS00450 7090595235d69b1bf4be32edaf3ce3ba 170 Pfam PF02082 Transcriptional regulator 1 81 5.2E-24 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type CDC59_RS00450 7090595235d69b1bf4be32edaf3ce3ba 170 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 131 1.1E-35 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type CDC59_RS00450 7090595235d69b1bf4be32edaf3ce3ba 170 SUPERFAMILY SSF46785 2 133 2.24E-39 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS13560 a5e992dcf4f9fde73c310356695be685 333 SUPERFAMILY SSF51905 291 332 1.27E-35 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS13560 a5e992dcf4f9fde73c310356695be685 333 SUPERFAMILY SSF51905 1 203 1.27E-35 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS13560 a5e992dcf4f9fde73c310356695be685 333 Gene3D G3DSA:3.90.660.10 50 292 6.7E-54 T 29-03-2018 CDC59_RS13560 a5e992dcf4f9fde73c310356695be685 333 PRINTS PR00419 Adrenodoxin reductase family signature 5 27 3.7E-6 T 29-03-2018 CDC59_RS13560 a5e992dcf4f9fde73c310356695be685 333 PRINTS PR00419 Adrenodoxin reductase family signature 28 41 3.7E-6 T 29-03-2018 CDC59_RS13560 a5e992dcf4f9fde73c310356695be685 333 Pfam PF01593 Flavin containing amine oxidoreductase 108 284 2.2E-12 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 CDC59_RS13560 a5e992dcf4f9fde73c310356695be685 333 Pfam PF13450 NAD(P)-binding Rossmann-like domain 8 71 3.4E-13 T 29-03-2018 CDC59_RS00785 0c8e7bd5a920602dfd3ac5a48ccd367f 201 Gene3D G3DSA:3.40.50.720 1 201 5.6E-30 T 29-03-2018 CDC59_RS00785 0c8e7bd5a920602dfd3ac5a48ccd367f 201 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 56 67 2.0E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS00785 0c8e7bd5a920602dfd3ac5a48ccd367f 201 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 2.0E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS00785 0c8e7bd5a920602dfd3ac5a48ccd367f 201 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 164 2.0E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS00785 0c8e7bd5a920602dfd3ac5a48ccd367f 201 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 146 2.0E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS00785 0c8e7bd5a920602dfd3ac5a48ccd367f 201 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 26 183 6.5E-17 T 29-03-2018 CDC59_RS00785 0c8e7bd5a920602dfd3ac5a48ccd367f 201 SUPERFAMILY SSF51735 2 192 1.17E-26 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS19165 bb88e3b8e9d7c76c672b18430803f89c 143 Gene3D G3DSA:3.30.70.1060 1 119 4.7E-30 T 29-03-2018 CDC59_RS19165 bb88e3b8e9d7c76c672b18430803f89c 143 SUPERFAMILY SSF54909 1 119 9.65E-29 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CDC59_RS19165 bb88e3b8e9d7c76c672b18430803f89c 143 Pfam PF03795 YCII-related domain 1 110 3.7E-14 T 29-03-2018 IPR005545 YCII-related CDC59_RS23300 c8d9a4fc1aa22d7fbb67b2c301c921ef 137 SUPERFAMILY SSF88723 3 135 4.21E-29 T 29-03-2018 IPR029060 PIN domain-like CDC59_RS23300 c8d9a4fc1aa22d7fbb67b2c301c921ef 137 Pfam PF01850 PIN domain 3 122 6.7E-16 T 29-03-2018 IPR002716 PIN domain CDC59_RS23300 c8d9a4fc1aa22d7fbb67b2c301c921ef 137 Gene3D G3DSA:3.40.50.1010 3 137 4.4E-27 T 29-03-2018 IPR029060 PIN domain-like CDC59_RS23300 c8d9a4fc1aa22d7fbb67b2c301c921ef 137 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 3 129 10.239 T 29-03-2018 IPR022907 VapC family GO:0004540 CDC59_RS19000 3c017a1f90c439fd80967814966ba2a1 163 Pfam PF07007 Lysozyme inhibitor LprI 68 155 4.4E-8 T 29-03-2018 IPR009739 Lysozyme inhibitor LprI, N-terminal CDC59_RS02195 6705cb3add3adbb42b2f2617074bd8ed 281 Pfam PF09906 Uncharacterized protein conserved in bacteria (DUF2135) 220 266 9.7E-20 T 29-03-2018 IPR019220 Domain of unknown function DUF2135 CDC59_RS02195 6705cb3add3adbb42b2f2617074bd8ed 281 PIRSF PIRSF012281 1 280 7.6E-122 T 29-03-2018 IPR012039 Uncharacterised conserved protein UCP012281 CDC59_RS02195 6705cb3add3adbb42b2f2617074bd8ed 281 Gene3D G3DSA:2.60.120.380 23 254 6.7E-5 T 29-03-2018 CDC59_RS01470 a952dbc32e4d7eb026b194a768679f26 171 Pfam PF12680 SnoaL-like domain 57 154 1.0E-10 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CDC59_RS01470 a952dbc32e4d7eb026b194a768679f26 171 Gene3D G3DSA:3.10.450.50 39 159 4.0E-17 T 29-03-2018 CDC59_RS01470 a952dbc32e4d7eb026b194a768679f26 171 SUPERFAMILY SSF54427 45 157 8.53E-18 T 29-03-2018 IPR032710 NTF2-like domain CDC59_RS12335 9aab6d161159d3f53157e5d7ba9a752d 192 Gene3D G3DSA:3.40.50.1240 1 191 2.7E-34 T 29-03-2018 IPR029033 Histidine phosphatase superfamily CDC59_RS12335 9aab6d161159d3f53157e5d7ba9a752d 192 SMART SM00855 2 152 2.3E-12 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CDC59_RS12335 9aab6d161159d3f53157e5d7ba9a752d 192 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 188 1.5E-35 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CDC59_RS12335 9aab6d161159d3f53157e5d7ba9a752d 192 SUPERFAMILY SSF53254 1 191 1.09E-37 T 29-03-2018 IPR029033 Histidine phosphatase superfamily CDC59_RS12335 9aab6d161159d3f53157e5d7ba9a752d 192 TIGRFAM TIGR03162 ribazole_cobC: alpha-ribazole phosphatase 3 175 9.6E-54 T 29-03-2018 IPR017578 Alpha-ribazole phosphatase, CobC GO:0009236|GO:0043755 KEGG: 00860+3.1.3.73|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CDC59_RS22285 d4b61c4c02a527449f1eb8272d5861eb 421 Pfam PF13458 Periplasmic binding protein 41 382 1.6E-72 T 29-03-2018 IPR028081 Leucine-binding protein domain CDC59_RS22285 d4b61c4c02a527449f1eb8272d5861eb 421 Gene3D G3DSA:3.40.50.2300 42 175 7.3E-19 T 29-03-2018 CDC59_RS22285 d4b61c4c02a527449f1eb8272d5861eb 421 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 64 80 4.0E-6 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CDC59_RS22285 d4b61c4c02a527449f1eb8272d5861eb 421 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 105 115 4.0E-6 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CDC59_RS22285 d4b61c4c02a527449f1eb8272d5861eb 421 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 42 58 4.0E-6 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CDC59_RS22285 d4b61c4c02a527449f1eb8272d5861eb 421 SUPERFAMILY SSF53822 41 415 4.37E-82 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CDC59_RS22285 d4b61c4c02a527449f1eb8272d5861eb 421 Gene3D G3DSA:3.40.50.2300 176 318 1.7E-31 T 29-03-2018 CDC59_RS04875 7df4ba84eff8d559e6ae0c9ba18f7900 174 ProSitePatterns PS00519 AsnC-type HTH domain signature. 21 47 - T 29-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site CDC59_RS04875 7df4ba84eff8d559e6ae0c9ba18f7900 174 Gene3D G3DSA:1.10.10.10 4 55 2.3E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS04875 7df4ba84eff8d559e6ae0c9ba18f7900 174 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 6.5E-15 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CDC59_RS04875 7df4ba84eff8d559e6ae0c9ba18f7900 174 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 6.5E-15 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CDC59_RS04875 7df4ba84eff8d559e6ae0c9ba18f7900 174 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 6.5E-15 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CDC59_RS04875 7df4ba84eff8d559e6ae0c9ba18f7900 174 Gene3D G3DSA:3.30.70.920 56 149 3.1E-25 T 29-03-2018 CDC59_RS04875 7df4ba84eff8d559e6ae0c9ba18f7900 174 Pfam PF13412 Winged helix-turn-helix DNA-binding 3 50 2.9E-19 T 29-03-2018 CDC59_RS04875 7df4ba84eff8d559e6ae0c9ba18f7900 174 Pfam PF01037 Lrp/AsnC ligand binding domain 69 143 2.5E-21 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CDC59_RS04875 7df4ba84eff8d559e6ae0c9ba18f7900 174 SUPERFAMILY SSF54909 64 147 1.88E-20 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CDC59_RS04875 7df4ba84eff8d559e6ae0c9ba18f7900 174 SUPERFAMILY SSF46785 2 62 2.32E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS04875 7df4ba84eff8d559e6ae0c9ba18f7900 174 SMART SM00344 3 112 2.1E-38 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CDC59_RS11245 2e631e3a6fce5e38dbbef751d6380278 175 SUPERFAMILY SSF55729 8 154 8.21E-12 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDC59_RS11245 2e631e3a6fce5e38dbbef751d6380278 175 Pfam PF00583 Acetyltransferase (GNAT) family 72 152 3.3E-6 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CDC59_RS11245 2e631e3a6fce5e38dbbef751d6380278 175 Gene3D G3DSA:3.40.630.30 7 164 2.0E-12 T 29-03-2018 CDC59_RS01410 653f88c5a6f429c41d19f72603c3a712 229 Pfam PF00550 Phosphopantetheine attachment site 104 167 1.4E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS01410 653f88c5a6f429c41d19f72603c3a712 229 SUPERFAMILY SSF56801 1 114 8.9E-28 T 29-03-2018 CDC59_RS01410 653f88c5a6f429c41d19f72603c3a712 229 ProSitePatterns PS00012 Phosphopantetheine attachment site. 126 141 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CDC59_RS01410 653f88c5a6f429c41d19f72603c3a712 229 Gene3D G3DSA:1.10.1200.10 106 175 1.1E-25 T 29-03-2018 CDC59_RS01410 653f88c5a6f429c41d19f72603c3a712 229 SUPERFAMILY SSF47336 94 167 2.22E-21 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS01410 653f88c5a6f429c41d19f72603c3a712 229 SMART SM01294 103 167 0.0085 T 29-03-2018 CDC59_RS01410 653f88c5a6f429c41d19f72603c3a712 229 SMART SM00823 Phosphopantetheine attachment site 102 171 8.2E-5 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CDC59_RS01410 653f88c5a6f429c41d19f72603c3a712 229 Pfam PF13193 AMP-binding enzyme C-terminal domain 1 75 4.4E-13 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CDC59_RS01410 653f88c5a6f429c41d19f72603c3a712 229 Gene3D G3DSA:3.30.300.30 1 105 1.9E-33 T 29-03-2018 CDC59_RS00640 f8c0f462d7b0e22a80a2909670c7709e 236 SMART SM00448 1 112 2.4E-36 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS00640 f8c0f462d7b0e22a80a2909670c7709e 236 Gene3D G3DSA:3.40.50.2300 1 119 1.6E-33 T 29-03-2018 CDC59_RS00640 f8c0f462d7b0e22a80a2909670c7709e 236 SUPERFAMILY SSF46894 126 231 6.24E-18 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CDC59_RS00640 f8c0f462d7b0e22a80a2909670c7709e 236 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 230 5.3E-17 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDC59_RS00640 f8c0f462d7b0e22a80a2909670c7709e 236 Gene3D G3DSA:1.10.10.10 120 236 1.1E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS00640 f8c0f462d7b0e22a80a2909670c7709e 236 Pfam PF00072 Response regulator receiver domain 3 113 1.1E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS00640 f8c0f462d7b0e22a80a2909670c7709e 236 SUPERFAMILY SSF52172 1 118 2.28E-37 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS00640 f8c0f462d7b0e22a80a2909670c7709e 236 SMART SM00862 149 230 2.8E-18 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDC59_RS20955 b967e7155b640cc8dc24e4ecef9f1d39 366 Gene3D G3DSA:3.40.50.2300 57 178 5.5E-16 T 29-03-2018 CDC59_RS20955 b967e7155b640cc8dc24e4ecef9f1d39 366 Gene3D G3DSA:3.40.50.2300 179 342 2.6E-7 T 29-03-2018 CDC59_RS20955 b967e7155b640cc8dc24e4ecef9f1d39 366 Pfam PF13407 Periplasmic binding protein domain 60 321 8.1E-22 T 29-03-2018 IPR025997 Periplasmic binding protein CDC59_RS20955 b967e7155b640cc8dc24e4ecef9f1d39 366 SUPERFAMILY SSF53822 57 341 3.73E-29 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CDC59_RS23110 eb77c0d9f2f24d2ff261b6fbbf3d4689 137 SMART SM00448 4 120 7.6E-35 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS23110 eb77c0d9f2f24d2ff261b6fbbf3d4689 137 Gene3D G3DSA:3.40.50.2300 1 136 1.3E-36 T 29-03-2018 CDC59_RS23110 eb77c0d9f2f24d2ff261b6fbbf3d4689 137 Pfam PF00072 Response regulator receiver domain 6 119 1.5E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS23110 eb77c0d9f2f24d2ff261b6fbbf3d4689 137 SUPERFAMILY SSF52172 1 130 1.57E-37 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS17360 385ac470252855dcb5337ec765f5142a 263 SUPERFAMILY SSF51621 8 252 2.79E-64 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CDC59_RS17360 385ac470252855dcb5337ec765f5142a 263 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 20 211 2.8E-30 T 29-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 CDC59_RS17360 385ac470252855dcb5337ec765f5142a 263 Gene3D G3DSA:3.20.20.60 1 255 1.2E-35 T 29-03-2018 CDC59_RS20080 a30674b06cdb22c3a84e5fd0b710697e 231 SUPERFAMILY SSF53955 24 149 3.49E-40 T 29-03-2018 IPR023346 Lysozyme-like domain CDC59_RS20080 a30674b06cdb22c3a84e5fd0b710697e 231 Pfam PF01464 Transglycosylase SLT domain 32 128 5.5E-18 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 CDC59_RS20080 a30674b06cdb22c3a84e5fd0b710697e 231 Gene3D G3DSA:1.10.530.10 25 215 2.3E-20 T 29-03-2018 CDC59_RS07850 c962b9cc694d23f6741122eadbfba5e0 270 PRINTS PR00377 Inositol monophosphatase superfamily signature 60 76 3.3E-60 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CDC59_RS07850 c962b9cc694d23f6741122eadbfba5e0 270 PRINTS PR00377 Inositol monophosphatase superfamily signature 84 100 3.3E-60 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CDC59_RS07850 c962b9cc694d23f6741122eadbfba5e0 270 PRINTS PR00377 Inositol monophosphatase superfamily signature 133 156 3.3E-60 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CDC59_RS07850 c962b9cc694d23f6741122eadbfba5e0 270 PRINTS PR00377 Inositol monophosphatase superfamily signature 211 235 3.3E-60 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CDC59_RS07850 c962b9cc694d23f6741122eadbfba5e0 270 PRINTS PR00377 Inositol monophosphatase superfamily signature 38 58 3.3E-60 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CDC59_RS07850 c962b9cc694d23f6741122eadbfba5e0 270 PRINTS PR00377 Inositol monophosphatase superfamily signature 180 201 3.3E-60 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CDC59_RS07850 c962b9cc694d23f6741122eadbfba5e0 270 Gene3D G3DSA:3.30.540.10 1 152 1.5E-50 T 29-03-2018 CDC59_RS07850 c962b9cc694d23f6741122eadbfba5e0 270 PRINTS PR01959 SuhB family inositol monophosphatase signature 107 126 1.6E-24 T 29-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 CDC59_RS07850 c962b9cc694d23f6741122eadbfba5e0 270 PRINTS PR01959 SuhB family inositol monophosphatase signature 201 213 1.6E-24 T 29-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 CDC59_RS07850 c962b9cc694d23f6741122eadbfba5e0 270 PRINTS PR01959 SuhB family inositol monophosphatase signature 17 39 1.6E-24 T 29-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 CDC59_RS07850 c962b9cc694d23f6741122eadbfba5e0 270 PRINTS PR01959 SuhB family inositol monophosphatase signature 159 185 1.6E-24 T 29-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 CDC59_RS07850 c962b9cc694d23f6741122eadbfba5e0 270 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 214 228 - T 29-03-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 CDC59_RS07850 c962b9cc694d23f6741122eadbfba5e0 270 Pfam PF00459 Inositol monophosphatase family 2 252 5.7E-67 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CDC59_RS07850 c962b9cc694d23f6741122eadbfba5e0 270 SUPERFAMILY SSF56655 1 258 1.06E-81 T 29-03-2018 CDC59_RS07850 c962b9cc694d23f6741122eadbfba5e0 270 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 84 97 - T 29-03-2018 IPR020583 Inositol monophosphatase, metal-binding site CDC59_RS07850 c962b9cc694d23f6741122eadbfba5e0 270 Gene3D G3DSA:3.40.190.80 153 270 1.3E-29 T 29-03-2018 CDC59_RS22200 eea13222daafd8449f2607e261458386 846 Pfam PF00202 Aminotransferase class-III 409 836 1.7E-100 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CDC59_RS22200 eea13222daafd8449f2607e261458386 846 Gene3D G3DSA:3.40.50.720 137 294 1.1E-16 T 29-03-2018 CDC59_RS22200 eea13222daafd8449f2607e261458386 846 Gene3D G3DSA:3.90.1150.10 377 548 6.1E-39 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS22200 eea13222daafd8449f2607e261458386 846 SUPERFAMILY SSF51735 148 274 7.32E-12 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS22200 eea13222daafd8449f2607e261458386 846 SUPERFAMILY SSF53383 787 839 4.26E-119 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS22200 eea13222daafd8449f2607e261458386 846 SUPERFAMILY SSF53383 393 745 4.26E-119 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS22200 eea13222daafd8449f2607e261458386 846 Gene3D G3DSA:3.40.640.10 549 681 1.9E-42 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDC59_RS22200 eea13222daafd8449f2607e261458386 846 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 605 642 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CDC59_RS22200 eea13222daafd8449f2607e261458386 846 Gene3D G3DSA:3.90.1150.10 682 845 1.8E-29 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS06840 2a69585cf4975daab802f7719f28cd5a 256 Gene3D G3DSA:2.120.10.10 41 209 2.8E-4 T 29-03-2018 CDC59_RS21665 faf4e029b10b12c91f8249d4bc382dac 245 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS21665 faf4e029b10b12c91f8249d4bc382dac 245 Pfam PF00005 ABC transporter 28 169 4.6E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS21665 faf4e029b10b12c91f8249d4bc382dac 245 SUPERFAMILY SSF52540 20 222 2.42E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS21665 faf4e029b10b12c91f8249d4bc382dac 245 SMART SM00382 27 218 1.4E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS21665 faf4e029b10b12c91f8249d4bc382dac 245 Gene3D G3DSA:3.40.50.300 7 227 1.7E-53 T 29-03-2018 CDC59_RS14060 befc722f99d5d8d543ec20240b92c33e 318 ProSitePatterns PS01173 Lipolytic enzymes "G-D-X-G" family, putative histidine active site. 79 95 - T 29-03-2018 IPR002168 Lipase, GDXG, putative histidine active site GO:0008152|GO:0016787 Reactome: R-HSA-163560 CDC59_RS14060 befc722f99d5d8d543ec20240b92c33e 318 Pfam PF07859 alpha/beta hydrolase fold 79 281 1.3E-57 T 29-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CDC59_RS14060 befc722f99d5d8d543ec20240b92c33e 318 SUPERFAMILY SSF53474 32 304 5.26E-58 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS14060 befc722f99d5d8d543ec20240b92c33e 318 Gene3D G3DSA:3.40.50.1820 10 314 1.4E-47 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS08315 24862760d5b9cad6a784250112402e6c 350 Pfam PF00356 Bacterial regulatory proteins, lacI family 10 53 6.4E-11 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDC59_RS08315 24862760d5b9cad6a784250112402e6c 350 SUPERFAMILY SSF47413 8 54 4.97E-10 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDC59_RS08315 24862760d5b9cad6a784250112402e6c 350 Gene3D G3DSA:1.10.260.40 1 64 9.8E-14 T 29-03-2018 CDC59_RS08315 24862760d5b9cad6a784250112402e6c 350 SMART SM00354 8 80 2.0E-5 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CDC59_RS08315 24862760d5b9cad6a784250112402e6c 350 Pfam PF13407 Periplasmic binding protein domain 77 327 2.9E-25 T 29-03-2018 IPR025997 Periplasmic binding protein CDC59_RS08315 24862760d5b9cad6a784250112402e6c 350 Gene3D G3DSA:3.40.50.2300 65 177 4.7E-13 T 29-03-2018 CDC59_RS08315 24862760d5b9cad6a784250112402e6c 350 SUPERFAMILY SSF53822 77 346 1.7E-32 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CDC59_RS08315 24862760d5b9cad6a784250112402e6c 350 Gene3D G3DSA:3.40.50.2300 178 350 1.1E-21 T 29-03-2018 CDC59_RS14770 4af6971264d8e726c83053d8df7bc601 235 Gene3D G3DSA:3.40.30.10 76 231 3.8E-35 T 29-03-2018 CDC59_RS14770 4af6971264d8e726c83053d8df7bc601 235 SUPERFAMILY SSF52833 77 229 1.06E-50 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS14770 4af6971264d8e726c83053d8df7bc601 235 PRINTS PR01011 Glutathione peroxidase family signature 96 113 1.4E-11 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CDC59_RS14770 4af6971264d8e726c83053d8df7bc601 235 PRINTS PR01011 Glutathione peroxidase family signature 191 200 1.4E-11 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CDC59_RS14770 4af6971264d8e726c83053d8df7bc601 235 PRINTS PR01011 Glutathione peroxidase family signature 131 147 1.4E-11 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CDC59_RS14770 4af6971264d8e726c83053d8df7bc601 235 ProSitePatterns PS00460 Glutathione peroxidases active site. 98 113 - T 29-03-2018 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 CDC59_RS14770 4af6971264d8e726c83053d8df7bc601 235 Pfam PF00255 Glutathione peroxidase 80 183 4.4E-30 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CDC59_RS14770 4af6971264d8e726c83053d8df7bc601 235 PIRSF PIRSF000303 62 233 2.0E-57 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CDC59_RS13310 b29cb8de715e1ea231501c601c15038d 231 Pfam PF13419 Haloacid dehalogenase-like hydrolase 17 197 7.6E-33 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS13310 b29cb8de715e1ea231501c601c15038d 231 TIGRFAM TIGR01449 PGP_bact: phosphoglycolate phosphatase, bacterial 17 220 6.3E-53 T 29-03-2018 IPR006346 2-phosphoglycolate phosphatase, prokaryotic GO:0008967|GO:0046295 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 CDC59_RS13310 b29cb8de715e1ea231501c601c15038d 231 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 112 191 4.1E-10 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDC59_RS13310 b29cb8de715e1ea231501c601c15038d 231 Gene3D G3DSA:3.40.50.1000 105 225 2.4E-31 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS13310 b29cb8de715e1ea231501c601c15038d 231 Gene3D G3DSA:1.10.150.240 28 104 1.5E-17 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CDC59_RS13310 b29cb8de715e1ea231501c601c15038d 231 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 78 197 1.0E-8 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDC59_RS13310 b29cb8de715e1ea231501c601c15038d 231 SUPERFAMILY SSF56784 14 222 1.97E-51 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS20945 550a85cce3812365821dc36ca97c5faa 255 SUPERFAMILY SSF53474 8 248 7.97E-43 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS20945 550a85cce3812365821dc36ca97c5faa 255 SMART SM00824 Thioesterase 23 241 1.4E-5 T 29-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 CDC59_RS20945 550a85cce3812365821dc36ca97c5faa 255 Gene3D G3DSA:3.40.50.1820 3 251 2.2E-27 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS20945 550a85cce3812365821dc36ca97c5faa 255 Pfam PF00975 Thioesterase domain 20 244 1.3E-45 T 29-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CDC59_RS10095 1d27c16845cf724bff6c44d96ece8429 196 Pfam PF08896 Domain of unknown function (DUF1842) 4 117 1.8E-44 T 29-03-2018 IPR014992 Domain of unknown function DUF1842 CDC59_RS10095 1d27c16845cf724bff6c44d96ece8429 196 Pfam PF08898 Domain of unknown function (DUF1843) 143 194 6.6E-22 T 29-03-2018 IPR014994 Domain of unknown function DUF1843 CDC59_RS11550 b07bc02f469ccc7938f84f937041b5e3 257 Pfam PF03883 Peroxide stress protein YaaA 1 242 1.6E-90 T 29-03-2018 IPR005583 Peroxide stress protein YaaA CDC59_RS11550 b07bc02f469ccc7938f84f937041b5e3 257 Hamap MF_00652 UPF0246 protein YaaA [yaaA]. 1 255 37.876 T 29-03-2018 IPR005583 Peroxide stress protein YaaA CDC59_RS14565 6809983c08e15fa6714c3cb5de63b727 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 3.0E-43 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CDC59_RS14565 6809983c08e15fa6714c3cb5de63b727 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 29-03-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 CDC59_RS14565 6809983c08e15fa6714c3cb5de63b727 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 29-03-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 CDC59_RS14565 6809983c08e15fa6714c3cb5de63b727 112 PRINTS PR00340 P-II protein signature 83 103 5.7E-44 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CDC59_RS14565 6809983c08e15fa6714c3cb5de63b727 112 PRINTS PR00340 P-II protein signature 23 41 5.7E-44 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CDC59_RS14565 6809983c08e15fa6714c3cb5de63b727 112 PRINTS PR00340 P-II protein signature 2 17 5.7E-44 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CDC59_RS14565 6809983c08e15fa6714c3cb5de63b727 112 PRINTS PR00340 P-II protein signature 52 75 5.7E-44 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CDC59_RS14565 6809983c08e15fa6714c3cb5de63b727 112 SUPERFAMILY SSF54913 1 112 2.89E-46 T 29-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta CDC59_RS14565 6809983c08e15fa6714c3cb5de63b727 112 SMART SM00938 4 105 3.2E-67 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CDC59_RS14565 6809983c08e15fa6714c3cb5de63b727 112 Gene3D G3DSA:3.30.70.120 1 109 5.1E-50 T 29-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CDC59_RS14565 6809983c08e15fa6714c3cb5de63b727 112 PIRSF PIRSF039144 1 112 1.7E-54 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CDC59_RS09440 926555ff42f63c36abcd67f9163c5ff0 91 Pfam PF06945 Protein of unknown function (DUF1289) 33 76 1.5E-16 T 29-03-2018 IPR010710 Protein of unknown function DUF1289 CDC59_RS22335 53728e6639d15ef783e18cc579155333 2473 Gene3D G3DSA:1.25.10.10 442 1860 3.1E-15 T 29-03-2018 IPR011989 Armadillo-like helical CDC59_RS22335 53728e6639d15ef783e18cc579155333 2473 SUPERFAMILY SSF48371 293 815 2.46E-13 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 CDC59_RS22335 53728e6639d15ef783e18cc579155333 2473 Gene3D G3DSA:3.30.460.10 2213 2356 0.033 T 29-03-2018 CDC59_RS05335 60d358ae646e2e91705a5afa3756feea 108 Pfam PF10109 Phage tail assembly chaperone proteins, E, or 41 or 14 5 74 1.7E-6 T 29-03-2018 IPR019289 Bacteriophage tail protein Gp41, putative CDC59_RS04525 6590512a17c49adac263214ef41036c6 240 Pfam PF03724 META domain 121 229 7.1E-18 T 29-03-2018 IPR005184 Domain of unknown function DUF306, Meta/HslJ CDC59_RS16225 f66ba2f4f7fa474ea61f748091d584a1 101 TIGRFAM TIGR02684 dnstrm_HI1420: probable addiction module antidote protein 9 98 2.8E-37 T 29-03-2018 IPR014057 Addiction module antidote protein, HI1420 CDC59_RS16225 f66ba2f4f7fa474ea61f748091d584a1 101 SUPERFAMILY SSF47413 38 97 6.75E-10 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDC59_RS16225 f66ba2f4f7fa474ea61f748091d584a1 101 Gene3D G3DSA:1.10.260.40 3 99 1.6E-6 T 29-03-2018 CDC59_RS16225 f66ba2f4f7fa474ea61f748091d584a1 101 Pfam PF01381 Helix-turn-helix 53 96 3.5E-6 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDC59_RS00520 bab7f959c90ff0c974aed836b28a524c 204 PIRSF PIRSF001296 15 204 1.1E-75 T 29-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CDC59_RS00520 bab7f959c90ff0c974aed836b28a524c 204 Hamap MF_00276 Potassium-transporting ATPase KdpC subunit [kdpC]. 16 203 35.95 T 29-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CDC59_RS00520 bab7f959c90ff0c974aed836b28a524c 204 TIGRFAM TIGR00681 kdpC: K+-transporting ATPase, C subunit 19 202 1.2E-69 T 29-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CDC59_RS00520 bab7f959c90ff0c974aed836b28a524c 204 Pfam PF02669 K+-transporting ATPase, c chain 20 201 2.7E-72 T 29-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CDC59_RS08865 c8ae5fa97f9789bdfbd8e148359190bd 327 Gene3D G3DSA:1.10.3720.10 27 289 1.9E-42 T 29-03-2018 CDC59_RS08865 c8ae5fa97f9789bdfbd8e148359190bd 327 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 283 4.6E-16 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS08865 c8ae5fa97f9789bdfbd8e148359190bd 327 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 25 283 2.1E-98 T 29-03-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 CDC59_RS08865 c8ae5fa97f9789bdfbd8e148359190bd 327 TIGRFAM TIGR02140 permease_CysW: sulfate ABC transporter, permease protein CysW 26 285 1.0E-127 T 29-03-2018 IPR011866 Sulphate ABC transporter, permease protein CysW GO:0008272|GO:0015116|GO:0016021 CDC59_RS08865 c8ae5fa97f9789bdfbd8e148359190bd 327 SUPERFAMILY SSF161098 25 276 5.1E-55 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS06700 01dace92ff9b8ce7be4c6792daaf19c2 151 Pfam PF05154 TM2 domain 8 55 2.1E-9 T 29-03-2018 IPR007829 TM2 domain CDC59_RS20365 da3d225614dc1276f686a464752ef685 201 SMART SM00530 23 78 9.4E-16 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDC59_RS20365 da3d225614dc1276f686a464752ef685 201 Gene3D G3DSA:2.60.120.10 89 201 1.2E-11 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CDC59_RS20365 da3d225614dc1276f686a464752ef685 201 SUPERFAMILY SSF51182 71 200 3.45E-20 T 29-03-2018 IPR011051 RmlC-like cupin domain CDC59_RS20365 da3d225614dc1276f686a464752ef685 201 Gene3D G3DSA:1.10.260.40 11 88 7.1E-18 T 29-03-2018 CDC59_RS20365 da3d225614dc1276f686a464752ef685 201 Pfam PF01381 Helix-turn-helix 24 78 1.2E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDC59_RS20365 da3d225614dc1276f686a464752ef685 201 SUPERFAMILY SSF47413 19 84 7.88E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDC59_RS07795 328ddec609da2b06dcd8e50859700fa1 174 Gene3D G3DSA:3.10.50.40 1 168 8.3E-18 T 29-03-2018 CDC59_RS07795 328ddec609da2b06dcd8e50859700fa1 174 SUPERFAMILY SSF54534 2 141 6.68E-29 T 29-03-2018 CDC59_RS17175 6bd9f6dd9f3eb0533484c67bca3f2753 610 TIGRFAM TIGR00206 fliF: flagellar M-ring protein FliF 50 608 7.7E-124 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CDC59_RS17175 6bd9f6dd9f3eb0533484c67bca3f2753 610 Pfam PF01514 Secretory protein of YscJ/FliF family 54 243 6.1E-76 T 29-03-2018 IPR006182 Secretory protein YscJ/FliF CDC59_RS17175 6bd9f6dd9f3eb0533484c67bca3f2753 610 PIRSF PIRSF004862 38 610 2.4E-145 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CDC59_RS17175 6bd9f6dd9f3eb0533484c67bca3f2753 610 Gene3D G3DSA:3.30.70.1530 75 138 9.2E-10 T 29-03-2018 CDC59_RS17175 6bd9f6dd9f3eb0533484c67bca3f2753 610 Pfam PF08345 Flagellar M-ring protein C-terminal 276 469 2.2E-49 T 29-03-2018 IPR013556 Flagellar M-ring C-terminal CDC59_RS17175 6bd9f6dd9f3eb0533484c67bca3f2753 610 PRINTS PR01009 Flagellar M-ring protein signature 289 307 3.1E-39 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CDC59_RS17175 6bd9f6dd9f3eb0533484c67bca3f2753 610 PRINTS PR01009 Flagellar M-ring protein signature 398 422 3.1E-39 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CDC59_RS17175 6bd9f6dd9f3eb0533484c67bca3f2753 610 PRINTS PR01009 Flagellar M-ring protein signature 176 190 3.1E-39 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CDC59_RS17175 6bd9f6dd9f3eb0533484c67bca3f2753 610 PRINTS PR01009 Flagellar M-ring protein signature 219 237 3.1E-39 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CDC59_RS17175 6bd9f6dd9f3eb0533484c67bca3f2753 610 PRINTS PR01009 Flagellar M-ring protein signature 144 162 3.1E-39 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CDC59_RS21710 a9def953a50bb2584665f5f4603292c7 146 SUPERFAMILY SSF52402 1 146 3.43E-26 T 29-03-2018 CDC59_RS21710 a9def953a50bb2584665f5f4603292c7 146 Pfam PF00582 Universal stress protein family 1 146 1.7E-26 T 29-03-2018 IPR006016 UspA GO:0006950 CDC59_RS21710 a9def953a50bb2584665f5f4603292c7 146 PRINTS PR01438 Universal stress protein signature 2 20 9.4E-9 T 29-03-2018 IPR006015 Universal stress protein A CDC59_RS21710 a9def953a50bb2584665f5f4603292c7 146 PRINTS PR01438 Universal stress protein signature 124 146 9.4E-9 T 29-03-2018 IPR006015 Universal stress protein A CDC59_RS21710 a9def953a50bb2584665f5f4603292c7 146 Gene3D G3DSA:3.40.50.620 1 146 4.4E-26 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDC59_RS04000 e0cdf25352639556dcc66d5730e860df 957 Gene3D G3DSA:3.30.460.10 108 286 1.7E-55 T 29-03-2018 CDC59_RS04000 e0cdf25352639556dcc66d5730e860df 957 Gene3D G3DSA:3.30.460.10 655 815 4.5E-51 T 29-03-2018 CDC59_RS04000 e0cdf25352639556dcc66d5730e860df 957 SUPERFAMILY SSF81593 289 456 1.73E-40 T 29-03-2018 CDC59_RS04000 e0cdf25352639556dcc66d5730e860df 957 Hamap MF_00802 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme [glnE]. 22 949 19.371 T 29-03-2018 IPR023057 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme GO:0008882 CDC59_RS04000 e0cdf25352639556dcc66d5730e860df 957 Pfam PF08335 GlnD PII-uridylyltransferase 831 919 6.7E-7 T 29-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 CDC59_RS04000 e0cdf25352639556dcc66d5730e860df 957 Pfam PF08335 GlnD PII-uridylyltransferase 300 456 2.5E-44 T 29-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 CDC59_RS04000 e0cdf25352639556dcc66d5730e860df 957 SUPERFAMILY SSF81301 544 819 1.11E-74 T 29-03-2018 CDC59_RS04000 e0cdf25352639556dcc66d5730e860df 957 Gene3D G3DSA:1.10.4050.10 13 107 0.11 T 29-03-2018 CDC59_RS04000 e0cdf25352639556dcc66d5730e860df 957 Gene3D G3DSA:1.10.4050.10 548 654 4.7E-20 T 29-03-2018 CDC59_RS04000 e0cdf25352639556dcc66d5730e860df 957 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 572 808 2.6E-65 T 29-03-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 CDC59_RS04000 e0cdf25352639556dcc66d5730e860df 957 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 31 266 3.8E-63 T 29-03-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 CDC59_RS04000 e0cdf25352639556dcc66d5730e860df 957 Gene3D G3DSA:1.20.120.330 287 460 9.6E-46 T 29-03-2018 CDC59_RS04000 e0cdf25352639556dcc66d5730e860df 957 SUPERFAMILY SSF81593 822 948 4.0E-28 T 29-03-2018 CDC59_RS04000 e0cdf25352639556dcc66d5730e860df 957 SUPERFAMILY SSF81301 25 288 9.27E-71 T 29-03-2018 CDC59_RS04000 e0cdf25352639556dcc66d5730e860df 957 Gene3D G3DSA:1.20.120.330 816 950 6.0E-31 T 29-03-2018 CDC59_RS17100 d502f076d311d427c2e1854db157d05f 130 TIGRFAM TIGR03500 FliO_TIGR: flagellar biosynthetic protein FliO 14 86 5.5E-23 T 29-03-2018 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 CDC59_RS17100 d502f076d311d427c2e1854db157d05f 130 Pfam PF04347 Flagellar biosynthesis protein, FliO 26 118 2.4E-23 T 29-03-2018 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 CDC59_RS01790 3bd63ce49602fe8c0a03f086ae4839a5 182 Pfam PF02525 Flavodoxin-like fold 5 172 1.1E-44 T 29-03-2018 IPR003680 Flavodoxin-like fold CDC59_RS01790 3bd63ce49602fe8c0a03f086ae4839a5 182 SUPERFAMILY SSF52218 4 176 7.75E-48 T 29-03-2018 IPR029039 Flavoprotein-like domain CDC59_RS01790 3bd63ce49602fe8c0a03f086ae4839a5 182 Gene3D G3DSA:3.40.50.360 1 180 8.8E-41 T 29-03-2018 IPR029039 Flavoprotein-like domain CDC59_RS05765 34041c4dc55123005df2bec85684b100 264 Pfam PF00290 Tryptophan synthase alpha chain 17 246 6.3E-61 T 29-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CDC59_RS05765 34041c4dc55123005df2bec85684b100 264 SUPERFAMILY SSF51366 6 258 6.31E-71 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CDC59_RS05765 34041c4dc55123005df2bec85684b100 264 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 19 259 1.5E-54 T 29-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CDC59_RS05765 34041c4dc55123005df2bec85684b100 264 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 53 66 - T 29-03-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CDC59_RS05765 34041c4dc55123005df2bec85684b100 264 Gene3D G3DSA:3.20.20.70 7 260 7.5E-61 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS05765 34041c4dc55123005df2bec85684b100 264 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 19 262 26.55 T 29-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CDC59_RS12860 67632e622d6124fe83864631da7d8506 255 Pfam PF01925 Sulfite exporter TauE/SafE 13 250 1.1E-35 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CDC59_RS05140 ebd19968abda0b8331d5497eda6cad28 130 ProDom PD456999 SIGNAL PRECURSOR TRANSMEMBRANE MEMBRANE YOHN INTEGRAL EXPORTED SIMILAR LIPOPROTEIN LIPOPROTEIN 73 123 1.0E-20 T 29-03-2018 IPR024572 Nickel/cobalt homeostasis protein RcnB CDC59_RS05140 ebd19968abda0b8331d5497eda6cad28 130 Pfam PF11776 Nickel/cobalt transporter regulator 76 124 2.1E-22 T 29-03-2018 IPR024572 Nickel/cobalt homeostasis protein RcnB CDC59_RS05140 ebd19968abda0b8331d5497eda6cad28 130 Gene3D G3DSA:3.10.450.160 21 129 1.2E-19 T 29-03-2018 CDC59_RS03580 2b9f23dad686485724103230542b8b57 169 Pfam PF04390 Lipopolysaccharide-assembly 36 162 2.1E-14 T 29-03-2018 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 CDC59_RS03580 2b9f23dad686485724103230542b8b57 169 Gene3D G3DSA:3.30.160.150 24 169 2.6E-39 T 29-03-2018 CDC59_RS03580 2b9f23dad686485724103230542b8b57 169 Hamap MF_01186 LPS-assembly lipoprotein LptE [lptE]. 9 167 25.303 T 29-03-2018 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 CDC59_RS17895 3660d993be11f063ead673d5948a7a4a 218 SUPERFAMILY SSF46785 61 172 2.22E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS17895 3660d993be11f063ead673d5948a7a4a 218 Gene3D G3DSA:1.10.10.10 52 162 5.8E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS17895 3660d993be11f063ead673d5948a7a4a 218 Pfam PF03551 Transcriptional regulator PadR-like family 65 133 2.3E-16 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal CDC59_RS15290 cc1b1923130da354d1bf1d52d67a8422 312 Gene3D G3DSA:3.40.50.620 4 231 1.4E-39 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDC59_RS15290 cc1b1923130da354d1bf1d52d67a8422 312 Hamap MF_01850 tRNA 2-thiocytidine biosynthesis protein TtcA [ttcA]. 2 263 56.398 T 29-03-2018 IPR012089 2-thiocytidine tRNA biosynthesis protein, TtcA GO:0008033 CDC59_RS15290 cc1b1923130da354d1bf1d52d67a8422 312 SUPERFAMILY SSF52402 13 227 2.14E-54 T 29-03-2018 CDC59_RS15290 cc1b1923130da354d1bf1d52d67a8422 312 PIRSF PIRSF004976 4 264 2.2E-72 T 29-03-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 CDC59_RS15290 cc1b1923130da354d1bf1d52d67a8422 312 Pfam PF01171 PP-loop family 34 195 1.2E-14 T 29-03-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 CDC59_RS10275 f4f278dd64c412e6340cabc51b049305 397 Gene3D G3DSA:3.40.630.10 4 290 4.0E-58 T 29-03-2018 CDC59_RS10275 f4f278dd64c412e6340cabc51b049305 397 SUPERFAMILY SSF55031 183 289 5.68E-21 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CDC59_RS10275 f4f278dd64c412e6340cabc51b049305 397 Pfam PF01546 Peptidase family M20/M25/M40 76 387 2.8E-37 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CDC59_RS10275 f4f278dd64c412e6340cabc51b049305 397 TIGRFAM TIGR01892 AcOrn-deacetyl: acetylornithine deacetylase (ArgE) 15 386 3.3E-121 T 29-03-2018 IPR010169 Acetylornithine deacetylase ArgE GO:0005737|GO:0006526|GO:0008777 KEGG: 00220+3.5.1.16|MetaCyc: PWY-5154 CDC59_RS10275 f4f278dd64c412e6340cabc51b049305 397 SUPERFAMILY SSF53187 10 182 2.46E-58 T 29-03-2018 CDC59_RS10275 f4f278dd64c412e6340cabc51b049305 397 SUPERFAMILY SSF53187 309 390 2.46E-58 T 29-03-2018 CDC59_RS10275 f4f278dd64c412e6340cabc51b049305 397 Pfam PF07687 Peptidase dimerisation domain 179 288 5.7E-21 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CDC59_RS10275 f4f278dd64c412e6340cabc51b049305 397 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 109 146 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CDC59_RS09835 9e16d1bd83447cc31feaeffd0a54abdd 288 PRINTS PR01415 Ankyrin repeat signature 178 192 1.4E-8 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CDC59_RS09835 9e16d1bd83447cc31feaeffd0a54abdd 288 PRINTS PR01415 Ankyrin repeat signature 130 145 1.4E-8 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CDC59_RS09835 9e16d1bd83447cc31feaeffd0a54abdd 288 SMART SM00248 98 128 34.0 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CDC59_RS09835 9e16d1bd83447cc31feaeffd0a54abdd 288 SMART SM00248 162 191 4.2E-7 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CDC59_RS09835 9e16d1bd83447cc31feaeffd0a54abdd 288 SMART SM00248 64 94 360.0 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CDC59_RS09835 9e16d1bd83447cc31feaeffd0a54abdd 288 SMART SM00248 129 158 7.2E-6 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CDC59_RS09835 9e16d1bd83447cc31feaeffd0a54abdd 288 Pfam PF12796 Ankyrin repeats (3 copies) 106 193 1.0E-21 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CDC59_RS09835 9e16d1bd83447cc31feaeffd0a54abdd 288 Gene3D G3DSA:1.25.40.20 23 107 2.7E-14 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CDC59_RS09835 9e16d1bd83447cc31feaeffd0a54abdd 288 SUPERFAMILY SSF48403 36 216 1.87E-41 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CDC59_RS09835 9e16d1bd83447cc31feaeffd0a54abdd 288 Gene3D G3DSA:1.25.40.20 108 224 1.9E-34 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CDC59_RS07070 77164cade7af4580ddb7118bb722b5b4 590 SUPERFAMILY SSF53474 379 566 2.13E-64 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS07070 77164cade7af4580ddb7118bb722b5b4 590 SUPERFAMILY SSF53474 97 351 2.13E-64 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS07070 77164cade7af4580ddb7118bb722b5b4 590 Gene3D G3DSA:3.40.50.1820 96 540 4.2E-54 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS07070 77164cade7af4580ddb7118bb722b5b4 590 Pfam PF00450 Serine carboxypeptidase 109 290 1.5E-16 T 29-03-2018 IPR001563 Peptidase S10, serine carboxypeptidase GO:0004185|GO:0006508 CDC59_RS12510 786e3b57e46d424358866b3f90983e3f 341 Gene3D G3DSA:3.40.50.720 15 196 4.3E-12 T 29-03-2018 CDC59_RS12510 786e3b57e46d424358866b3f90983e3f 341 SUPERFAMILY SSF51735 152 302 1.86E-25 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS12510 786e3b57e46d424358866b3f90983e3f 341 SUPERFAMILY SSF51735 20 123 1.86E-25 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS12510 786e3b57e46d424358866b3f90983e3f 341 Gene3D G3DSA:3.90.25.10 209 338 1.4E-8 T 29-03-2018 CDC59_RS19965 bb239b614f70a4ca4dc13855bf93bc73 409 SUPERFAMILY SSF111369 51 301 7.19E-89 T 29-03-2018 CDC59_RS19965 bb239b614f70a4ca4dc13855bf93bc73 409 Gene3D G3DSA:1.20.1600.10 76 338 1.4E-31 T 29-03-2018 CDC59_RS19965 bb239b614f70a4ca4dc13855bf93bc73 409 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 40 376 3.2E-85 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 CDC59_RS19965 bb239b614f70a4ca4dc13855bf93bc73 409 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 65 294 2.3E-14 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CDC59_RS23690 978cda7edf171b9d6bb8d917f127e3a3 456 Pfam PF04966 Carbohydrate-selective porin, OprB family 94 456 4.2E-106 T 29-03-2018 IPR007049 Carbohydrate-selective porin OprB GO:0005215|GO:0006810|GO:0016021 CDC59_RS20530 290c83a7b7612742df6516b471aa84e7 313 PIRSF PIRSF000428 6 305 1.6E-89 T 29-03-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CDC59_RS20530 290c83a7b7612742df6516b471aa84e7 313 Pfam PF01515 Phosphate acetyl/butaryl transferase 83 297 1.2E-45 T 29-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CDC59_RS20530 290c83a7b7612742df6516b471aa84e7 313 Gene3D G3DSA:3.40.50.10750 119 274 4.8E-47 T 29-03-2018 CDC59_RS20530 290c83a7b7612742df6516b471aa84e7 313 SUPERFAMILY SSF53659 12 301 2.71E-66 T 29-03-2018 CDC59_RS04765 0ae94caed5deb810f68b6f83cf7e133d 371 Pfam PF04143 Sulphur transport 30 358 1.2E-61 T 29-03-2018 IPR007272 Sulphur transport domain CDC59_RS00850 517abd66367bcfe19d7cdd1bc5b2e652 467 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 79 3.3E-17 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CDC59_RS00850 517abd66367bcfe19d7cdd1bc5b2e652 467 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 339 348 - T 29-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CDC59_RS00850 517abd66367bcfe19d7cdd1bc5b2e652 467 SUPERFAMILY SSF52540 83 353 8.74E-89 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS00850 517abd66367bcfe19d7cdd1bc5b2e652 467 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 466 9.7E-249 T 29-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 CDC59_RS00850 517abd66367bcfe19d7cdd1bc5b2e652 467 Gene3D G3DSA:1.10.1140.10 354 464 1.0E-44 T 29-03-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CDC59_RS00850 517abd66367bcfe19d7cdd1bc5b2e652 467 Gene3D G3DSA:3.40.50.300 82 353 1.0E-89 T 29-03-2018 CDC59_RS00850 517abd66367bcfe19d7cdd1bc5b2e652 467 SUPERFAMILY SSF47917 351 466 2.88E-54 T 29-03-2018 CDC59_RS00850 517abd66367bcfe19d7cdd1bc5b2e652 467 Gene3D G3DSA:2.40.10.170 1 81 3.1E-27 T 29-03-2018 CDC59_RS00850 517abd66367bcfe19d7cdd1bc5b2e652 467 SMART SM00382 148 333 0.001 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS00850 517abd66367bcfe19d7cdd1bc5b2e652 467 SUPERFAMILY SSF50615 3 81 1.23E-23 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CDC59_RS00850 517abd66367bcfe19d7cdd1bc5b2e652 467 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 466 56.495 T 29-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 CDC59_RS00850 517abd66367bcfe19d7cdd1bc5b2e652 467 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 136 348 3.4E-63 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CDC59_RS06765 55453f67ddd2a022e3162cb5fba1f614 219 Pfam PF00929 Exonuclease 31 192 5.6E-34 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CDC59_RS06765 55453f67ddd2a022e3162cb5fba1f614 219 SMART SM00479 29 202 6.1E-24 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CDC59_RS06765 55453f67ddd2a022e3162cb5fba1f614 219 SUPERFAMILY SSF53098 26 201 6.17E-48 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDC59_RS06765 55453f67ddd2a022e3162cb5fba1f614 219 Gene3D G3DSA:3.30.420.10 24 203 6.4E-29 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDC59_RS06765 55453f67ddd2a022e3162cb5fba1f614 219 Hamap MF_00045 Oligoribonuclease [orn]. 25 203 43.935 T 29-03-2018 IPR022894 Oligoribonuclease GO:0000175 CDC59_RS03210 648acc7ae528732d7f9a46668ab19101 204 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 3 195 3.7E-48 T 29-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CDC59_RS03210 648acc7ae528732d7f9a46668ab19101 204 SUPERFAMILY SSF52540 3 197 1.24E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS03210 648acc7ae528732d7f9a46668ab19101 204 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 1 204 27.301 T 29-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CDC59_RS03210 648acc7ae528732d7f9a46668ab19101 204 Pfam PF01121 Dephospho-CoA kinase 3 188 7.3E-56 T 29-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CDC59_RS03210 648acc7ae528732d7f9a46668ab19101 204 Gene3D G3DSA:3.40.50.300 1 198 2.7E-39 T 29-03-2018 CDC59_RS13700 436c157d030509ccb07a76bd98288d7c 100 Pfam PF09907 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system 20 92 4.9E-32 T 29-03-2018 IPR018669 Toxin-antitoxin system, toxin component, HigB, putative GO:0016788 CDC59_RS04405 79424e2d8aefa19e0a45678f482334f5 181 Gene3D G3DSA:2.40.50.180 55 142 2.6E-9 T 29-03-2018 CDC59_RS04405 79424e2d8aefa19e0a45678f482334f5 181 SMART SM00260 32 168 2.2E-4 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CDC59_RS04405 79424e2d8aefa19e0a45678f482334f5 181 Pfam PF01584 CheW-like domain 37 170 3.6E-17 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CDC59_RS04405 79424e2d8aefa19e0a45678f482334f5 181 SUPERFAMILY SSF50341 33 174 2.09E-19 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CDC59_RS20580 9d60b5f1f841a6660ce6a100618a7d8e 143 Pfam PF01724 Domain of unknown function DUF29 5 141 2.9E-46 T 29-03-2018 IPR002636 Protein from unkown function DUF29 CDC59_RS22005 027bb193ce0fe9d2521e18e7d9569ba2 590 Gene3D G3DSA:3.10.20.310 105 177 4.6E-10 T 29-03-2018 CDC59_RS22005 027bb193ce0fe9d2521e18e7d9569ba2 590 Pfam PF08479 POTRA domain, ShlB-type 121 177 2.0E-15 T 29-03-2018 IPR013686 Polypeptide-transport-associated, ShlB-type CDC59_RS22005 027bb193ce0fe9d2521e18e7d9569ba2 590 Pfam PF03865 Haemolysin secretion/activation protein ShlB/FhaC/HecB 236 550 2.1E-107 T 29-03-2018 IPR005565 Haemolysin activator HlyB, C-terminal CDC59_RS22005 027bb193ce0fe9d2521e18e7d9569ba2 590 Gene3D G3DSA:2.40.160.50 204 590 1.1E-48 T 29-03-2018 CDC59_RS22005 027bb193ce0fe9d2521e18e7d9569ba2 590 PIRSF PIRSF029745 2 590 1.6E-145 T 29-03-2018 IPR027282 Two partner secretion pathway transporter GO:0015031 CDC59_RS22005 027bb193ce0fe9d2521e18e7d9569ba2 590 Pfam PF17287 POTRA domain 179 231 5.4E-21 T 29-03-2018 IPR035251 ShlB, POTRA domain CDC59_RS07295 b3140453d66f7144b77e63cdba7a3e2f 354 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 339 157.498 T 29-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 CDC59_RS07295 b3140453d66f7144b77e63cdba7a3e2f 354 Gene3D G3DSA:3.40.718.10 1 336 4.8E-108 T 29-03-2018 CDC59_RS07295 b3140453d66f7144b77e63cdba7a3e2f 354 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 3 335 8.5E-117 T 29-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 CDC59_RS07295 b3140453d66f7144b77e63cdba7a3e2f 354 PIRSF PIRSF002465 1 338 2.4E-131 T 29-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 CDC59_RS07295 b3140453d66f7144b77e63cdba7a3e2f 354 Pfam PF02504 Fatty acid synthesis protein 3 325 2.1E-110 T 29-03-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 CDC59_RS07295 b3140453d66f7144b77e63cdba7a3e2f 354 SUPERFAMILY SSF53659 3 335 1.93E-105 T 29-03-2018 CDC59_RS10240 d466e827b09b604ebc112dbcf8ff750d 240 SMART SM00862 158 234 1.8E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDC59_RS10240 d466e827b09b604ebc112dbcf8ff750d 240 Gene3D G3DSA:1.10.10.10 129 240 4.2E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS10240 d466e827b09b604ebc112dbcf8ff750d 240 Gene3D G3DSA:3.40.50.2300 1 128 9.4E-39 T 29-03-2018 CDC59_RS10240 d466e827b09b604ebc112dbcf8ff750d 240 Pfam PF00486 Transcriptional regulatory protein, C terminal 159 234 8.4E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDC59_RS10240 d466e827b09b604ebc112dbcf8ff750d 240 SMART SM00448 6 117 2.9E-45 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS10240 d466e827b09b604ebc112dbcf8ff750d 240 Pfam PF00072 Response regulator receiver domain 8 117 1.1E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS10240 d466e827b09b604ebc112dbcf8ff750d 240 SUPERFAMILY SSF52172 3 125 6.12E-43 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS10240 d466e827b09b604ebc112dbcf8ff750d 240 SUPERFAMILY SSF46894 135 236 4.25E-29 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CDC59_RS10585 770346a5f5045d601dcb7945457480c5 306 Pfam PF12852 Cupin 2 185 9.4E-32 T 29-03-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain CDC59_RS10585 770346a5f5045d601dcb7945457480c5 306 Gene3D G3DSA:2.60.120.280 17 173 9.0E-17 T 29-03-2018 CDC59_RS10585 770346a5f5045d601dcb7945457480c5 306 Pfam PF12833 Helix-turn-helix domain 224 302 2.2E-20 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CDC59_RS10585 770346a5f5045d601dcb7945457480c5 306 Gene3D G3DSA:1.10.260.40 233 267 0.002 T 29-03-2018 CDC59_RS10585 770346a5f5045d601dcb7945457480c5 306 SMART SM00342 218 301 9.4E-27 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CDC59_RS10585 770346a5f5045d601dcb7945457480c5 306 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 270 285 9.6E-7 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CDC59_RS10585 770346a5f5045d601dcb7945457480c5 306 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 285 301 9.6E-7 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CDC59_RS10585 770346a5f5045d601dcb7945457480c5 306 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 255 297 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CDC59_RS10585 770346a5f5045d601dcb7945457480c5 306 Gene3D G3DSA:1.10.10.60 174 232 0.025 T 29-03-2018 CDC59_RS10585 770346a5f5045d601dcb7945457480c5 306 SUPERFAMILY SSF51215 6 77 2.22E-7 T 29-03-2018 CDC59_RS10585 770346a5f5045d601dcb7945457480c5 306 SUPERFAMILY SSF46689 254 303 3.9E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS10585 770346a5f5045d601dcb7945457480c5 306 SUPERFAMILY SSF46689 202 252 8.51E-6 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS10585 770346a5f5045d601dcb7945457480c5 306 Gene3D G3DSA:1.10.10.60 268 304 6.4E-15 T 29-03-2018 CDC59_RS04160 b2ed67b56471bf70581cd7e7ad5b37f2 356 Pfam PF01594 AI-2E family transporter 15 341 1.7E-55 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like CDC59_RS16635 4bbc82573def4c9c59aac77e1ba1b1bd 494 Gene3D G3DSA:1.25.40.20 36 251 2.2E-30 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CDC59_RS16635 4bbc82573def4c9c59aac77e1ba1b1bd 494 SUPERFAMILY SSF48403 88 489 3.55E-36 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CDC59_RS16635 4bbc82573def4c9c59aac77e1ba1b1bd 494 SMART SM00248 192 221 0.0024 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CDC59_RS16635 4bbc82573def4c9c59aac77e1ba1b1bd 494 SMART SM00248 117 146 3200.0 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CDC59_RS16635 4bbc82573def4c9c59aac77e1ba1b1bd 494 SMART SM00248 433 462 9.9E-5 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CDC59_RS16635 4bbc82573def4c9c59aac77e1ba1b1bd 494 SMART SM00248 323 353 180.0 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CDC59_RS16635 4bbc82573def4c9c59aac77e1ba1b1bd 494 SMART SM00248 393 429 78.0 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CDC59_RS16635 4bbc82573def4c9c59aac77e1ba1b1bd 494 SMART SM00248 149 188 130.0 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CDC59_RS16635 4bbc82573def4c9c59aac77e1ba1b1bd 494 SMART SM00248 83 112 770.0 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CDC59_RS16635 4bbc82573def4c9c59aac77e1ba1b1bd 494 SMART SM00248 359 388 820.0 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CDC59_RS16635 4bbc82573def4c9c59aac77e1ba1b1bd 494 Gene3D G3DSA:1.25.40.20 341 489 3.5E-28 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CDC59_RS16635 4bbc82573def4c9c59aac77e1ba1b1bd 494 Pfam PF13857 Ankyrin repeats (many copies) 420 474 8.1E-10 T 29-03-2018 CDC59_RS16635 4bbc82573def4c9c59aac77e1ba1b1bd 494 Pfam PF13857 Ankyrin repeats (many copies) 179 233 2.9E-6 T 29-03-2018 CDC59_RS16635 4bbc82573def4c9c59aac77e1ba1b1bd 494 Gene3D G3DSA:1.25.40.20 252 340 2.2E-4 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CDC59_RS18355 501a751cdae728c69af9e80d6c3167a4 176 SUPERFAMILY SSF52540 4 162 7.23E-23 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS18355 501a751cdae728c69af9e80d6c3167a4 176 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 4 136 4.6E-45 T 29-03-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 CDC59_RS18355 501a751cdae728c69af9e80d6c3167a4 176 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 4 159 2.8E-45 T 29-03-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 CDC59_RS18355 501a751cdae728c69af9e80d6c3167a4 176 Gene3D G3DSA:3.40.50.300 1 168 3.0E-26 T 29-03-2018 CDC59_RS08265 10bcff9b93caf85379d42f36e1e9803d 91 ProDom PD029191 TRAFFICKING IRON PROBABLE FE2 YGGX FEII 3D-STRUCTURE OXIDATIVE CONTROL DIRECT 1 75 4.0E-39 T 29-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 CDC59_RS08265 10bcff9b93caf85379d42f36e1e9803d 91 Pfam PF04362 Bacterial Fe(2+) trafficking 1 88 1.7E-44 T 29-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 CDC59_RS08265 10bcff9b93caf85379d42f36e1e9803d 91 PIRSF PIRSF029827 1 90 1.8E-41 T 29-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 CDC59_RS08265 10bcff9b93caf85379d42f36e1e9803d 91 SUPERFAMILY SSF111148 1 89 1.12E-40 T 29-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 CDC59_RS08265 10bcff9b93caf85379d42f36e1e9803d 91 Gene3D G3DSA:1.10.3880.10 2 89 3.9E-42 T 29-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 CDC59_RS08265 10bcff9b93caf85379d42f36e1e9803d 91 Hamap MF_00686 Probable Fe(2+)-trafficking protein [yggX]. 1 88 28.929 T 29-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 CDC59_RS21290 3ff325fef7432be84acef112cc04cdf2 482 ProSitePatterns PS00609 Glycosyl hydrolases family 32 active site. 21 34 - T 29-03-2018 IPR018053 Glycoside hydrolase, family 32, active site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 CDC59_RS21290 3ff325fef7432be84acef112cc04cdf2 482 Gene3D G3DSA:2.115.10.20 26 344 1.9E-93 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CDC59_RS21290 3ff325fef7432be84acef112cc04cdf2 482 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 21 326 2.3E-93 T 29-03-2018 IPR013148 Glycosyl hydrolase family 32, N-terminal CDC59_RS21290 3ff325fef7432be84acef112cc04cdf2 482 Gene3D G3DSA:2.60.120.560 345 478 1.1E-19 T 29-03-2018 CDC59_RS21290 3ff325fef7432be84acef112cc04cdf2 482 SMART SM00640 21 441 1.1E-123 T 29-03-2018 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 CDC59_RS21290 3ff325fef7432be84acef112cc04cdf2 482 SUPERFAMILY SSF75005 12 326 5.18E-102 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CDC59_RS21290 3ff325fef7432be84acef112cc04cdf2 482 SUPERFAMILY SSF49899 326 477 3.8E-21 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CDC59_RS21290 3ff325fef7432be84acef112cc04cdf2 482 Pfam PF08244 Glycosyl hydrolases family 32 C terminal 353 474 5.2E-13 T 29-03-2018 IPR013189 Glycosyl hydrolase family 32, C-terminal CDC59_RS21290 3ff325fef7432be84acef112cc04cdf2 482 TIGRFAM TIGR01322 scrB_fam: sucrose-6-phosphate hydrolase 11 451 2.6E-138 T 29-03-2018 IPR006232 Sucrose-6-phosphate hydrolase GO:0004564|GO:0005737|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 CDC59_RS20495 cd0488a543d479972a7c9a5c39e9e7b1 243 Pfam PF10042 Uncharacterized conserved protein (DUF2278) 2 228 6.6E-48 T 29-03-2018 IPR019268 Protein of unknown function DUF2278 CDC59_RS14455 221bf6cb9dcca2688ac41d94bfccfe50 202 PIRSF PIRSF005413 9 201 4.6E-65 T 29-03-2018 IPR007533 Cytochrome c oxidase assembly protein CtaG/Cox11 GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS14455 221bf6cb9dcca2688ac41d94bfccfe50 202 Pfam PF04442 Cytochrome c oxidase assembly protein CtaG/Cox11 43 186 5.2E-48 T 29-03-2018 IPR007533 Cytochrome c oxidase assembly protein CtaG/Cox11 GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS14455 221bf6cb9dcca2688ac41d94bfccfe50 202 Gene3D G3DSA:2.60.370.10 72 190 2.2E-42 T 29-03-2018 IPR023471 Cytochrome c oxidase assembly protein CtaG/Cox11, domain Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS14455 221bf6cb9dcca2688ac41d94bfccfe50 202 SUPERFAMILY SSF110111 70 188 2.75E-45 T 29-03-2018 IPR023471 Cytochrome c oxidase assembly protein CtaG/Cox11, domain Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS15040 49eef7b6c336316f20e4948bb904d5e6 323 SMART SM00849 24 220 1.3E-24 T 29-03-2018 IPR001279 Metallo-beta-lactamase CDC59_RS15040 49eef7b6c336316f20e4948bb904d5e6 323 Pfam PF00753 Metallo-beta-lactamase superfamily 38 220 6.9E-23 T 29-03-2018 IPR001279 Metallo-beta-lactamase CDC59_RS15040 49eef7b6c336316f20e4948bb904d5e6 323 SUPERFAMILY SSF56281 25 241 5.74E-43 T 29-03-2018 IPR001279 Metallo-beta-lactamase CDC59_RS15040 49eef7b6c336316f20e4948bb904d5e6 323 Gene3D G3DSA:3.60.15.10 11 276 2.1E-35 T 29-03-2018 IPR001279 Metallo-beta-lactamase CDC59_RS15040 49eef7b6c336316f20e4948bb904d5e6 323 ProSitePatterns PS00743 Beta-lactamases class B signature 1. 73 93 - T 29-03-2018 IPR001018 Beta-lactamase, class-B, conserved site GO:0008270|GO:0008800|GO:0017001 CDC59_RS10225 6bd050059b056b99bb5313b0646e2e45 394 Pfam PF07394 Protein of unknown function (DUF1501) 38 345 1.1E-36 T 29-03-2018 IPR010869 Protein of unknown function DUF1501 CDC59_RS10225 6bd050059b056b99bb5313b0646e2e45 394 Gene3D G3DSA:3.40.720.10 111 385 8.0E-6 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CDC59_RS10225 6bd050059b056b99bb5313b0646e2e45 394 Pfam PF10518 TAT (twin-arginine translocation) pathway signal sequence 2 23 4.4E-5 T 29-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal CDC59_RS02165 8808011fa31a460f9075b9af4be02ac8 1409 Pfam PF00623 RNA polymerase Rpb1, domain 2 345 397 4.5E-8 T 29-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDC59_RS02165 8808011fa31a460f9075b9af4be02ac8 1409 Pfam PF00623 RNA polymerase Rpb1, domain 2 392 486 1.9E-27 T 29-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDC59_RS02165 8808011fa31a460f9075b9af4be02ac8 1409 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 19 1025 0.0 T 29-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDC59_RS02165 8808011fa31a460f9075b9af4be02ac8 1409 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 10 1383 18.914 T 29-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDC59_RS02165 8808011fa31a460f9075b9af4be02ac8 1409 Pfam PF04997 RNA polymerase Rpb1, domain 1 15 343 8.1E-86 T 29-03-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDC59_RS02165 8808011fa31a460f9075b9af4be02ac8 1409 Gene3D G3DSA:2.40.50.100 913 1015 4.3E-31 T 29-03-2018 CDC59_RS02165 8808011fa31a460f9075b9af4be02ac8 1409 Gene3D G3DSA:2.40.50.100 1016 1046 0.001 T 29-03-2018 CDC59_RS02165 8808011fa31a460f9075b9af4be02ac8 1409 Pfam PF04983 RNA polymerase Rpb1, domain 3 490 650 4.6E-21 T 29-03-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDC59_RS02165 8808011fa31a460f9075b9af4be02ac8 1409 Gene3D G3DSA:2.40.50.100 1174 1219 2.8E-11 T 29-03-2018 CDC59_RS02165 8808011fa31a460f9075b9af4be02ac8 1409 Pfam PF04998 RNA polymerase Rpb1, domain 5 772 1322 1.3E-77 T 29-03-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDC59_RS02165 8808011fa31a460f9075b9af4be02ac8 1409 SMART SM00663 236 515 9.5E-173 T 29-03-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDC59_RS02165 8808011fa31a460f9075b9af4be02ac8 1409 Gene3D G3DSA:2.40.50.100 1047 1116 1.9E-11 T 29-03-2018 CDC59_RS02165 8808011fa31a460f9075b9af4be02ac8 1409 SUPERFAMILY SSF64484 1140 1371 0.0 T 29-03-2018 CDC59_RS02165 8808011fa31a460f9075b9af4be02ac8 1409 SUPERFAMILY SSF64484 16 950 0.0 T 29-03-2018 CDC59_RS02165 8808011fa31a460f9075b9af4be02ac8 1409 Gene3D G3DSA:2.40.50.100 1117 1173 0.01 T 29-03-2018 CDC59_RS02165 8808011fa31a460f9075b9af4be02ac8 1409 Gene3D G3DSA:2.40.40.20 347 489 4.5E-40 T 29-03-2018 CDC59_RS02165 8808011fa31a460f9075b9af4be02ac8 1409 Pfam PF05000 RNA polymerase Rpb1, domain 4 679 769 9.7E-19 T 29-03-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CDC59_RS17655 917fe696f72f76cb5006be9ecab32fd9 288 SUPERFAMILY SSF53850 25 272 1.04E-67 T 29-03-2018 CDC59_RS17655 917fe696f72f76cb5006be9ecab32fd9 288 Gene3D G3DSA:3.40.190.10 40 154 4.5E-36 T 29-03-2018 CDC59_RS17655 917fe696f72f76cb5006be9ecab32fd9 288 SMART SM00062 50 273 4.7E-72 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CDC59_RS17655 917fe696f72f76cb5006be9ecab32fd9 288 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 51 271 2.6E-61 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CDC59_RS17655 917fe696f72f76cb5006be9ecab32fd9 288 SMART SM00079 50 272 0.0026 T 29-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 CDC59_RS17655 917fe696f72f76cb5006be9ecab32fd9 288 Gene3D G3DSA:3.40.190.10 155 278 2.2E-14 T 29-03-2018 CDC59_RS10510 91dbc0dbd9d023702abcbf0f6ff98b6a 210 Pfam PF00072 Response regulator receiver domain 15 125 6.5E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS10510 91dbc0dbd9d023702abcbf0f6ff98b6a 210 SMART SM00421 149 206 1.1E-21 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS10510 91dbc0dbd9d023702abcbf0f6ff98b6a 210 Gene3D G3DSA:1.10.10.10 124 210 1.0E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS10510 91dbc0dbd9d023702abcbf0f6ff98b6a 210 Gene3D G3DSA:3.40.50.2300 2 123 2.4E-29 T 29-03-2018 CDC59_RS10510 91dbc0dbd9d023702abcbf0f6ff98b6a 210 SUPERFAMILY SSF46894 142 208 3.4E-20 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CDC59_RS10510 91dbc0dbd9d023702abcbf0f6ff98b6a 210 SMART SM00448 13 125 6.9E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS10510 91dbc0dbd9d023702abcbf0f6ff98b6a 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 2.5E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS10510 91dbc0dbd9d023702abcbf0f6ff98b6a 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 2.5E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS10510 91dbc0dbd9d023702abcbf0f6ff98b6a 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 2.5E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS10510 91dbc0dbd9d023702abcbf0f6ff98b6a 210 SUPERFAMILY SSF52172 12 161 4.41E-33 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS10510 91dbc0dbd9d023702abcbf0f6ff98b6a 210 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 206 1.0E-20 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS10510 91dbc0dbd9d023702abcbf0f6ff98b6a 210 ProSitePatterns PS00622 LuxR-type HTH domain signature. 166 193 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS16180 3baeb9a1104159a2f3ce54ff0b4e9d8a 257 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 254 7.0E-61 T 29-03-2018 CDC59_RS16180 3baeb9a1104159a2f3ce54ff0b4e9d8a 257 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 176 0.0026 T 29-03-2018 CDC59_RS16180 3baeb9a1104159a2f3ce54ff0b4e9d8a 257 Gene3D G3DSA:3.40.50.720 1 44 1.1E-8 T 29-03-2018 CDC59_RS16180 3baeb9a1104159a2f3ce54ff0b4e9d8a 257 Gene3D G3DSA:3.40.50.720 45 257 3.4E-66 T 29-03-2018 CDC59_RS16180 3baeb9a1104159a2f3ce54ff0b4e9d8a 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 9.9E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS16180 3baeb9a1104159a2f3ce54ff0b4e9d8a 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 9.9E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS16180 3baeb9a1104159a2f3ce54ff0b4e9d8a 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 9.9E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS16180 3baeb9a1104159a2f3ce54ff0b4e9d8a 257 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CDC59_RS16180 3baeb9a1104159a2f3ce54ff0b4e9d8a 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 3.7E-45 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS16180 3baeb9a1104159a2f3ce54ff0b4e9d8a 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 3.7E-45 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS16180 3baeb9a1104159a2f3ce54ff0b4e9d8a 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 3.7E-45 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS16180 3baeb9a1104159a2f3ce54ff0b4e9d8a 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 3.7E-45 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS16180 3baeb9a1104159a2f3ce54ff0b4e9d8a 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 3.7E-45 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS16180 3baeb9a1104159a2f3ce54ff0b4e9d8a 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 3.7E-45 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS16180 3baeb9a1104159a2f3ce54ff0b4e9d8a 257 SUPERFAMILY SSF51735 4 257 4.91E-79 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS02640 2b2fc168e8ebc8207cf74fde368b7a16 358 SMART SM00382 28 217 1.3E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS02640 2b2fc168e8ebc8207cf74fde368b7a16 358 SUPERFAMILY SSF52540 4 247 4.54E-79 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS02640 2b2fc168e8ebc8207cf74fde368b7a16 358 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS02640 2b2fc168e8ebc8207cf74fde368b7a16 358 Gene3D G3DSA:3.40.50.300 3 265 4.2E-71 T 29-03-2018 CDC59_RS02640 2b2fc168e8ebc8207cf74fde368b7a16 358 Pfam PF00005 ABC transporter 19 167 5.4E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS02275 849ee9dcaaa1c9161a19da48a671b841 64 Pfam PF00831 Ribosomal L29 protein 4 60 2.1E-22 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS02275 849ee9dcaaa1c9161a19da48a671b841 64 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 60 4.7E-20 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS02275 849ee9dcaaa1c9161a19da48a671b841 64 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 17.554 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS02275 849ee9dcaaa1c9161a19da48a671b841 64 SUPERFAMILY SSF46561 1 60 1.96E-20 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS02275 849ee9dcaaa1c9161a19da48a671b841 64 Gene3D G3DSA:1.10.287.310 1 64 1.9E-21 T 29-03-2018 CDC59_RS02275 849ee9dcaaa1c9161a19da48a671b841 64 ProSitePatterns PS00579 Ribosomal protein L29 signature. 39 53 - T 29-03-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS10280 b95dd36166114837e088c643960a8ab1 285 Gene3D G3DSA:3.40.50.1000 136 282 9.7E-26 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS10280 b95dd36166114837e088c643960a8ab1 285 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 78 247 3.1E-29 T 29-03-2018 CDC59_RS10280 b95dd36166114837e088c643960a8ab1 285 Gene3D G3DSA:1.10.150.210 88 135 3.9E-23 T 29-03-2018 IPR023190 Phosphoserine phosphatase, domain 2 GO:0004647|GO:0006564 KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|Reactome: R-HSA-977347 CDC59_RS10280 b95dd36166114837e088c643960a8ab1 285 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 76 280 2.3E-65 T 29-03-2018 CDC59_RS10280 b95dd36166114837e088c643960a8ab1 285 Pfam PF13284 Domain of unknown function (DUF4072) 3 52 1.0E-11 T 29-03-2018 IPR025138 Domain of unknown function DUF4072 CDC59_RS10280 b95dd36166114837e088c643960a8ab1 285 SUPERFAMILY SSF56784 75 282 3.39E-47 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS10280 b95dd36166114837e088c643960a8ab1 285 Pfam PF12710 haloacid dehalogenase-like hydrolase 80 247 6.4E-19 T 29-03-2018 CDC59_RS01795 5c357b489659a1d5595972f038fbde3f 632 TIGRFAM TIGR00932 2a37: transporter, monovalent cation:proton antiporter-2 (CPA2) family 14 286 2.5E-85 T 29-03-2018 IPR004771 K+/H+ exchanger GO:0006812|GO:0008324|GO:0016021 CDC59_RS01795 5c357b489659a1d5595972f038fbde3f 632 Pfam PF00999 Sodium/hydrogen exchanger family 12 375 9.7E-67 T 29-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CDC59_RS01795 5c357b489659a1d5595972f038fbde3f 632 SUPERFAMILY SSF51735 404 534 2.76E-34 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS01795 5c357b489659a1d5595972f038fbde3f 632 PRINTS PR00335 TrkA potassium uptake protein signature 450 460 5.1E-7 T 29-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CDC59_RS01795 5c357b489659a1d5595972f038fbde3f 632 PRINTS PR00335 TrkA potassium uptake protein signature 421 435 5.1E-7 T 29-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CDC59_RS01795 5c357b489659a1d5595972f038fbde3f 632 PRINTS PR00335 TrkA potassium uptake protein signature 404 418 5.1E-7 T 29-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CDC59_RS01795 5c357b489659a1d5595972f038fbde3f 632 PRINTS PR00335 TrkA potassium uptake protein signature 461 471 5.1E-7 T 29-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CDC59_RS01795 5c357b489659a1d5595972f038fbde3f 632 Pfam PF02254 TrkA-N domain 405 517 1.5E-23 T 29-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CDC59_RS01795 5c357b489659a1d5595972f038fbde3f 632 Gene3D G3DSA:3.40.50.720 399 562 1.7E-19 T 29-03-2018 CDC59_RS01795 5c357b489659a1d5595972f038fbde3f 632 Gene3D G3DSA:1.20.91.10 213 318 2.9E-13 T 29-03-2018 CDC59_RS03090 e8ffe3fd4186f156d95fda292b50eaf5 319 SUPERFAMILY SSF53335 11 116 5.75E-44 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS03090 e8ffe3fd4186f156d95fda292b50eaf5 319 SUPERFAMILY SSF53335 220 318 5.75E-44 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS03090 e8ffe3fd4186f156d95fda292b50eaf5 319 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 10 318 8.3E-102 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CDC59_RS03090 e8ffe3fd4186f156d95fda292b50eaf5 319 Pfam PF01795 MraW methylase family 9 318 6.4E-98 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CDC59_RS03090 e8ffe3fd4186f156d95fda292b50eaf5 319 Gene3D G3DSA:1.10.150.170 115 222 3.0E-36 T 29-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CDC59_RS03090 e8ffe3fd4186f156d95fda292b50eaf5 319 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 11 319 36.756 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CDC59_RS03090 e8ffe3fd4186f156d95fda292b50eaf5 319 SUPERFAMILY SSF81799 117 220 3.14E-32 T 29-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CDC59_RS03090 e8ffe3fd4186f156d95fda292b50eaf5 319 PIRSF PIRSF004486 5 319 2.3E-94 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CDC59_RS21015 a010f71e3b5c35afda13b37aceb5245e 430 Gene3D G3DSA:3.50.50.60 6 116 2.2E-9 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS21015 a010f71e3b5c35afda13b37aceb5245e 430 Gene3D G3DSA:3.30.9.10 120 196 1.4E-6 T 29-03-2018 CDC59_RS21015 a010f71e3b5c35afda13b37aceb5245e 430 SUPERFAMILY SSF51905 25 256 4.4E-46 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS21015 a010f71e3b5c35afda13b37aceb5245e 430 SUPERFAMILY SSF51905 351 399 4.4E-46 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS21015 a010f71e3b5c35afda13b37aceb5245e 430 Gene3D G3DSA:3.30.9.10 197 350 9.5E-27 T 29-03-2018 CDC59_RS21015 a010f71e3b5c35afda13b37aceb5245e 430 Pfam PF01266 FAD dependent oxidoreductase 26 386 3.0E-61 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CDC59_RS23075 1e413701e983fd7798255ac5c8e7c651 133 SMART SM00448 6 122 4.5E-36 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS23075 1e413701e983fd7798255ac5c8e7c651 133 SUPERFAMILY SSF52172 5 128 5.98E-35 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS23075 1e413701e983fd7798255ac5c8e7c651 133 Gene3D G3DSA:3.40.50.2300 1 131 5.1E-36 T 29-03-2018 CDC59_RS23075 1e413701e983fd7798255ac5c8e7c651 133 Pfam PF00072 Response regulator receiver domain 9 121 7.9E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS21500 5574c5e520eedbb3b026fd7b1a4527d9 353 Pfam PF15984 Bacterial collagen, middle region 80 274 4.8E-63 T 29-03-2018 IPR031929 Bacterial collagen-like protein, middle domain CDC59_RS21500 5574c5e520eedbb3b026fd7b1a4527d9 353 Gene3D G3DSA:1.20.120.20 47 272 1.8E-7 T 29-03-2018 CDC59_RS12415 0ee7f7fe0e05f050b96bc774bae55ad4 506 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 27 148 5.5E-26 T 29-03-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CDC59_RS12415 0ee7f7fe0e05f050b96bc774bae55ad4 506 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 197 497 1.7E-127 T 29-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CDC59_RS12415 0ee7f7fe0e05f050b96bc774bae55ad4 506 SUPERFAMILY SSF53187 190 504 1.73E-125 T 29-03-2018 CDC59_RS12415 0ee7f7fe0e05f050b96bc774bae55ad4 506 Gene3D G3DSA:3.40.220.10 10 173 9.2E-32 T 29-03-2018 CDC59_RS12415 0ee7f7fe0e05f050b96bc774bae55ad4 506 Gene3D G3DSA:3.40.630.10 182 504 1.0E-138 T 29-03-2018 CDC59_RS12415 0ee7f7fe0e05f050b96bc774bae55ad4 506 PRINTS PR00481 Cytosol aminopeptidase signature 382 397 2.4E-54 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CDC59_RS12415 0ee7f7fe0e05f050b96bc774bae55ad4 506 PRINTS PR00481 Cytosol aminopeptidase signature 332 353 2.4E-54 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CDC59_RS12415 0ee7f7fe0e05f050b96bc774bae55ad4 506 PRINTS PR00481 Cytosol aminopeptidase signature 354 374 2.4E-54 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CDC59_RS12415 0ee7f7fe0e05f050b96bc774bae55ad4 506 PRINTS PR00481 Cytosol aminopeptidase signature 273 290 2.4E-54 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CDC59_RS12415 0ee7f7fe0e05f050b96bc774bae55ad4 506 PRINTS PR00481 Cytosol aminopeptidase signature 295 316 2.4E-54 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CDC59_RS12415 0ee7f7fe0e05f050b96bc774bae55ad4 506 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 358 365 - T 29-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CDC59_RS12415 0ee7f7fe0e05f050b96bc774bae55ad4 506 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 11 506 37.544 T 29-03-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 CDC59_RS12415 0ee7f7fe0e05f050b96bc774bae55ad4 506 SUPERFAMILY SSF52949 1 195 2.3E-38 T 29-03-2018 CDC59_RS04985 0f4615c694dca7b207e143371a0ffa60 182 SMART SM01322 1 176 7.5E-124 T 29-03-2018 IPR009822 YaeQ CDC59_RS04985 0f4615c694dca7b207e143371a0ffa60 182 PIRSF PIRSF011484 1 181 2.9E-76 T 29-03-2018 IPR009822 YaeQ CDC59_RS04985 0f4615c694dca7b207e143371a0ffa60 182 SUPERFAMILY SSF52980 2 178 2.44E-74 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CDC59_RS04985 0f4615c694dca7b207e143371a0ffa60 182 Pfam PF07152 YaeQ protein 1 173 7.4E-81 T 29-03-2018 IPR009822 YaeQ CDC59_RS04985 0f4615c694dca7b207e143371a0ffa60 182 Gene3D G3DSA:3.10.640.10 2 177 3.3E-82 T 29-03-2018 CDC59_RS17390 90eae99bd33524b8d906d9953a32717f 328 Pfam PF05598 Transposase domain (DUF772) 51 126 6.0E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS17390 90eae99bd33524b8d906d9953a32717f 328 Pfam PF01609 Transposase DDE domain 138 312 1.8E-31 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS10345 c0c75e2ffcefdfd73a083fad8930b2c0 370 SUPERFAMILY SSF55120 121 364 8.63E-76 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDC59_RS10345 c0c75e2ffcefdfd73a083fad8930b2c0 370 Pfam PF00849 RNA pseudouridylate synthase 137 291 6.6E-34 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDC59_RS10345 c0c75e2ffcefdfd73a083fad8930b2c0 370 SMART SM00363 62 127 1.2E-7 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CDC59_RS10345 c0c75e2ffcefdfd73a083fad8930b2c0 370 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 59 361 6.4E-92 T 29-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDC59_RS10345 c0c75e2ffcefdfd73a083fad8930b2c0 370 Gene3D G3DSA:3.10.290.10 47 119 1.6E-20 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CDC59_RS10345 c0c75e2ffcefdfd73a083fad8930b2c0 370 SUPERFAMILY SSF55174 62 149 2.02E-9 T 29-03-2018 CDC59_RS10345 c0c75e2ffcefdfd73a083fad8930b2c0 370 Gene3D G3DSA:3.30.2350.10 127 365 5.6E-70 T 29-03-2018 CDC59_RS10345 c0c75e2ffcefdfd73a083fad8930b2c0 370 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 179 193 - T 29-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 CDC59_RS10345 c0c75e2ffcefdfd73a083fad8930b2c0 370 Pfam PF01479 S4 domain 62 108 1.8E-9 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CDC59_RS18885 5596f1771c5683a851c68d79af230c68 407 Pfam PF00482 Type II secretion system (T2SS), protein F 278 399 2.8E-19 T 29-03-2018 IPR018076 Type II secretion system F domain CDC59_RS18885 5596f1771c5683a851c68d79af230c68 407 Pfam PF00482 Type II secretion system (T2SS), protein F 77 197 3.5E-22 T 29-03-2018 IPR018076 Type II secretion system F domain CDC59_RS18885 5596f1771c5683a851c68d79af230c68 407 PRINTS PR00812 Bacterial general secretion pathway protein F signature 388 407 8.6E-11 T 29-03-2018 IPR003004 GspF/PilC family CDC59_RS18885 5596f1771c5683a851c68d79af230c68 407 PRINTS PR00812 Bacterial general secretion pathway protein F signature 169 197 8.6E-11 T 29-03-2018 IPR003004 GspF/PilC family CDC59_RS18885 5596f1771c5683a851c68d79af230c68 407 PRINTS PR00812 Bacterial general secretion pathway protein F signature 372 386 8.6E-11 T 29-03-2018 IPR003004 GspF/PilC family CDC59_RS14475 c1432b5976de958177d122239c405a3a 313 Gene3D G3DSA:3.40.50.150 34 294 6.2E-31 T 29-03-2018 CDC59_RS14475 c1432b5976de958177d122239c405a3a 313 SUPERFAMILY SSF53335 13 206 3.84E-32 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS14475 c1432b5976de958177d122239c405a3a 313 Hamap MF_00835 Malonyl-[acyl-carrier protein] O-methyltransferase [bioC]. 7 285 26.293 T 29-03-2018 IPR011814 Malonyl-[acyl-carrier protein] O-methyltransferase BioC GO:0009102|GO:0010340 KEGG: 00670+2.1.1.19|KEGG: 00780+2.1.1.197|MetaCyc: PWY-2201|MetaCyc: PWY-6519 CDC59_RS14475 c1432b5976de958177d122239c405a3a 313 Pfam PF08241 Methyltransferase domain 52 161 3.9E-21 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CDC59_RS17620 243852277843603edc5f1c41b749b6fd 263 Gene3D G3DSA:2.60.120.620 1 254 1.6E-41 T 29-03-2018 CDC59_RS17620 243852277843603edc5f1c41b749b6fd 263 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 22 234 4.1E-39 T 29-03-2018 IPR008775 Phytanoyl-CoA dioxygenase CDC59_RS17620 243852277843603edc5f1c41b749b6fd 263 SUPERFAMILY SSF51197 11 252 4.12E-55 T 29-03-2018 CDC59_RS15985 dac0b4129b685ae0119425834497e2e4 319 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 5 266 5.6E-113 T 29-03-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 CDC59_RS15985 dac0b4129b685ae0119425834497e2e4 319 Gene3D G3DSA:3.90.550.10 1 291 4.8E-56 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDC59_RS15985 dac0b4129b685ae0119425834497e2e4 319 SUPERFAMILY SSF53448 5 279 3.68E-63 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDC59_RS15985 dac0b4129b685ae0119425834497e2e4 319 Pfam PF00483 Nucleotidyl transferase 12 266 1.4E-25 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CDC59_RS18680 c367f44f44fbcd99bf02a9286433f3e9 435 Gene3D G3DSA:1.20.1600.10 45 435 4.3E-53 T 29-03-2018 CDC59_RS18680 c367f44f44fbcd99bf02a9286433f3e9 435 SUPERFAMILY SSF56954 6 434 6.54E-66 T 29-03-2018 CDC59_RS18680 c367f44f44fbcd99bf02a9286433f3e9 435 Pfam PF02321 Outer membrane efflux protein 262 434 5.1E-22 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CDC59_RS18680 c367f44f44fbcd99bf02a9286433f3e9 435 Pfam PF02321 Outer membrane efflux protein 53 227 1.7E-15 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CDC59_RS15690 ab617ebcd1e5cc643b70fa000c345e06 334 Pfam PF01370 NAD dependent epimerase/dehydratase family 7 224 3.9E-14 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CDC59_RS15690 ab617ebcd1e5cc643b70fa000c345e06 334 SUPERFAMILY SSF51735 1 281 3.93E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS15690 ab617ebcd1e5cc643b70fa000c345e06 334 Gene3D G3DSA:3.40.50.720 5 320 5.5E-36 T 29-03-2018 CDC59_RS22305 ee4b4dd0b04dcef3a28f6f4737bcfcf8 236 Pfam PF00005 ABC transporter 20 160 4.6E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS22305 ee4b4dd0b04dcef3a28f6f4737bcfcf8 236 Gene3D G3DSA:3.40.50.300 1 235 6.7E-55 T 29-03-2018 CDC59_RS22305 ee4b4dd0b04dcef3a28f6f4737bcfcf8 236 SUPERFAMILY SSF52540 5 226 5.63E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS22305 ee4b4dd0b04dcef3a28f6f4737bcfcf8 236 SMART SM00382 29 209 1.7E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS23275 8d70643477f359617870c7b9f9a6cdb4 388 Gene3D G3DSA:2.40.30.20 34 111 8.9E-12 T 29-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS06870 e1c6042d8362b949d77eeeba11730487 107 Pfam PF07363 Protein of unknown function (DUF1484) 5 107 1.3E-33 T 29-03-2018 IPR009957 Protein of unknown function DUF1484 CDC59_RS04235 e5e7e508a76fc98b19a15b07ab0804b5 218 Pfam PF09335 SNARE associated Golgi protein 49 173 2.4E-22 T 29-03-2018 IPR032816 SNARE associated Golgi protein CDC59_RS19130 720127eed4bd85676f547644944249a0 357 Pfam PF03824 High-affinity nickel-transport protein 49 336 3.2E-85 T 29-03-2018 IPR011541 Nickel/cobalt transporter, high-affinity GO:0015099|GO:0016021|GO:0035444|GO:0046872 CDC59_RS19130 720127eed4bd85676f547644944249a0 357 TIGRFAM TIGR00802 nico: transition metal uptake transporter, Ni2+-Co2+ transporter (NiCoT) family 52 332 4.5E-119 T 29-03-2018 IPR004688 Transition metal uptake transporter nickel/cobalt GO:0015099|GO:0016021|GO:0035444|GO:0046872 CDC59_RS04620 0603a05af3e44a455317c66922d66f94 394 Pfam PF00155 Aminotransferase class I and II 37 387 1.3E-56 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CDC59_RS04620 0603a05af3e44a455317c66922d66f94 394 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 234 247 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CDC59_RS04620 0603a05af3e44a455317c66922d66f94 394 Gene3D G3DSA:3.90.1150.10 273 394 5.7E-27 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS04620 0603a05af3e44a455317c66922d66f94 394 SUPERFAMILY SSF53383 9 393 1.38E-101 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS04620 0603a05af3e44a455317c66922d66f94 394 Gene3D G3DSA:3.40.640.10 49 272 4.0E-50 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDC59_RS23165 d5cff613c3728c68cf821bea3b14da29 399 Gene3D G3DSA:3.40.190.10 188 281 7.7E-24 T 29-03-2018 CDC59_RS23165 d5cff613c3728c68cf821bea3b14da29 399 SUPERFAMILY SSF46785 5 86 4.69E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS23165 d5cff613c3728c68cf821bea3b14da29 399 SUPERFAMILY SSF53850 189 395 4.97E-40 T 29-03-2018 CDC59_RS23165 d5cff613c3728c68cf821bea3b14da29 399 SUPERFAMILY SSF46785 101 211 2.15E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS23165 d5cff613c3728c68cf821bea3b14da29 399 Gene3D G3DSA:3.40.190.10 282 365 1.5E-19 T 29-03-2018 CDC59_RS23165 d5cff613c3728c68cf821bea3b14da29 399 Gene3D G3DSA:1.10.10.10 1 86 7.2E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS23165 d5cff613c3728c68cf821bea3b14da29 399 Gene3D G3DSA:1.10.10.10 101 183 1.2E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS23165 d5cff613c3728c68cf821bea3b14da29 399 Pfam PF03466 LysR substrate binding domain 188 393 5.6E-38 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS23165 d5cff613c3728c68cf821bea3b14da29 399 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 104 161 4.0E-15 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS23165 d5cff613c3728c68cf821bea3b14da29 399 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 8.8E-13 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS23165 d5cff613c3728c68cf821bea3b14da29 399 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 118 129 2.3E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS23165 d5cff613c3728c68cf821bea3b14da29 399 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 139 150 2.3E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS23165 d5cff613c3728c68cf821bea3b14da29 399 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 129 139 2.3E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS12460 0a3016e5efc2ef2a8a603ac2cda5dd35 182 PIRSF PIRSF030820 1 180 8.4E-66 T 29-03-2018 IPR008318 Uncharacterised conserved protein UCP030820 CDC59_RS12460 0a3016e5efc2ef2a8a603ac2cda5dd35 182 Pfam PF06073 Bacterial protein of unknown function (DUF934) 66 171 3.1E-42 T 29-03-2018 IPR008318 Uncharacterised conserved protein UCP030820 CDC59_RS10050 ba5f1ac1e1907dbf920fb5f039f295bb 232 SMART SM00448 1 112 1.4E-37 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS10050 ba5f1ac1e1907dbf920fb5f039f295bb 232 Gene3D G3DSA:3.40.50.2300 1 120 1.7E-33 T 29-03-2018 CDC59_RS10050 ba5f1ac1e1907dbf920fb5f039f295bb 232 Pfam PF00072 Response regulator receiver domain 3 111 3.7E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS10050 ba5f1ac1e1907dbf920fb5f039f295bb 232 SUPERFAMILY SSF52172 1 170 1.85E-36 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS10050 ba5f1ac1e1907dbf920fb5f039f295bb 232 Gene3D G3DSA:1.10.10.10 121 222 2.0E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS10050 ba5f1ac1e1907dbf920fb5f039f295bb 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 218 4.3E-15 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDC59_RS10050 ba5f1ac1e1907dbf920fb5f039f295bb 232 SMART SM00862 145 218 1.1E-14 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDC59_RS22990 09abbac1263d04f750b96de0fecf6744 396 Gene3D G3DSA:3.90.176.10 183 377 2.5E-10 T 29-03-2018 CDC59_RS22990 09abbac1263d04f750b96de0fecf6744 396 SUPERFAMILY SSF56399 228 364 4.75E-11 T 29-03-2018 CDC59_RS22990 09abbac1263d04f750b96de0fecf6744 396 Gene3D G3DSA:3.40.220.10 17 182 7.5E-5 T 29-03-2018 CDC59_RS07885 9bf60dc963d628b1b65132f750ffa91f 465 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 4 464 4.8E-169 T 29-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 CDC59_RS07885 9bf60dc963d628b1b65132f750ffa91f 465 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 17 317 3.3E-128 T 29-03-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 CDC59_RS07885 9bf60dc963d628b1b65132f750ffa91f 465 Pfam PF09190 DALR domain 348 403 2.0E-18 T 29-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 CDC59_RS07885 9bf60dc963d628b1b65132f750ffa91f 465 SUPERFAMILY SSF52374 4 318 1.64E-97 T 29-03-2018 CDC59_RS07885 9bf60dc963d628b1b65132f750ffa91f 465 SUPERFAMILY SSF47323 321 463 1.83E-33 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CDC59_RS07885 9bf60dc963d628b1b65132f750ffa91f 465 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 4 464 38.696 T 29-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 CDC59_RS07885 9bf60dc963d628b1b65132f750ffa91f 465 Gene3D G3DSA:1.20.120.640 311 396 4.5E-20 T 29-03-2018 CDC59_RS07885 9bf60dc963d628b1b65132f750ffa91f 465 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 196 214 2.4E-29 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CDC59_RS07885 9bf60dc963d628b1b65132f750ffa91f 465 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 63 72 2.4E-29 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CDC59_RS07885 9bf60dc963d628b1b65132f750ffa91f 465 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 227 248 2.4E-29 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CDC59_RS07885 9bf60dc963d628b1b65132f750ffa91f 465 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 27 38 2.4E-29 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CDC59_RS07885 9bf60dc963d628b1b65132f750ffa91f 465 SMART SM00840 348 403 3.9E-26 T 29-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 CDC59_RS07885 9bf60dc963d628b1b65132f750ffa91f 465 Gene3D G3DSA:3.40.50.620 1 310 1.1E-89 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDC59_RS10490 7513608e97aa68fc2e3e3fef0827ce7c 557 Gene3D G3DSA:2.40.50.100 63 98 5.1E-5 T 29-03-2018 CDC59_RS10490 7513608e97aa68fc2e3e3fef0827ce7c 557 Gene3D G3DSA:2.40.50.100 3 62 7.3E-14 T 29-03-2018 CDC59_RS10490 7513608e97aa68fc2e3e3fef0827ce7c 557 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 333 556 1.4E-79 T 29-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CDC59_RS10490 7513608e97aa68fc2e3e3fef0827ce7c 557 TIGRFAM TIGR01348 PDHac_trf_long: dihydrolipoyllysine-residue acetyltransferase 105 557 1.0E-191 T 29-03-2018 IPR006256 Dihydrolipoamide acetyltransferase pyruvate dehydrogenase complex GO:0004742|GO:0006096|GO:0045254 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12 CDC59_RS10490 7513608e97aa68fc2e3e3fef0827ce7c 557 SUPERFAMILY SSF47005 248 289 1.57E-11 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CDC59_RS10490 7513608e97aa68fc2e3e3fef0827ce7c 557 Gene3D G3DSA:2.40.50.100 150 179 7.0E-15 T 29-03-2018 CDC59_RS10490 7513608e97aa68fc2e3e3fef0827ce7c 557 SUPERFAMILY SSF51230 3 97 3.4E-24 T 29-03-2018 IPR011053 Single hybrid motif CDC59_RS10490 7513608e97aa68fc2e3e3fef0827ce7c 557 Gene3D G3DSA:3.30.559.10 319 557 1.5E-80 T 29-03-2018 CDC59_RS10490 7513608e97aa68fc2e3e3fef0827ce7c 557 SUPERFAMILY SSF52777 319 557 1.02E-84 T 29-03-2018 CDC59_RS10490 7513608e97aa68fc2e3e3fef0827ce7c 557 Gene3D G3DSA:3.90.1170.30 180 214 0.0016 T 29-03-2018 CDC59_RS10490 7513608e97aa68fc2e3e3fef0827ce7c 557 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 144 173 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CDC59_RS10490 7513608e97aa68fc2e3e3fef0827ce7c 557 Gene3D G3DSA:4.10.320.10 245 309 8.3E-17 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CDC59_RS10490 7513608e97aa68fc2e3e3fef0827ce7c 557 Pfam PF00364 Biotin-requiring enzyme 6 75 2.5E-21 T 29-03-2018 IPR000089 Biotin/lipoyl attachment CDC59_RS10490 7513608e97aa68fc2e3e3fef0827ce7c 557 Pfam PF00364 Biotin-requiring enzyme 122 193 3.9E-22 T 29-03-2018 IPR000089 Biotin/lipoyl attachment CDC59_RS10490 7513608e97aa68fc2e3e3fef0827ce7c 557 SUPERFAMILY SSF51230 120 209 1.0E-23 T 29-03-2018 IPR011053 Single hybrid motif CDC59_RS10490 7513608e97aa68fc2e3e3fef0827ce7c 557 Gene3D G3DSA:2.40.50.100 118 149 0.014 T 29-03-2018 CDC59_RS10490 7513608e97aa68fc2e3e3fef0827ce7c 557 Pfam PF02817 e3 binding domain 251 285 9.3E-14 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CDC59_RS10490 7513608e97aa68fc2e3e3fef0827ce7c 557 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 28 57 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CDC59_RS22880 d52df59bca734420336b116e5408b0a2 252 SUPERFAMILY SSF46894 166 237 4.76E-18 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CDC59_RS22880 d52df59bca734420336b116e5408b0a2 252 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 197 213 4.6E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS22880 d52df59bca734420336b116e5408b0a2 252 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 197 4.6E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS22880 d52df59bca734420336b116e5408b0a2 252 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 213 225 4.6E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS22880 d52df59bca734420336b116e5408b0a2 252 Gene3D G3DSA:1.10.10.10 138 243 2.5E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS22880 d52df59bca734420336b116e5408b0a2 252 Pfam PF00196 Bacterial regulatory proteins, luxR family 182 235 2.2E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS22880 d52df59bca734420336b116e5408b0a2 252 SMART SM00421 180 237 1.2E-15 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS19735 038aa40e3fb1f088d324070d4c086b4a 328 TIGRFAM TIGR03373 VI_minor_4: type VI secretion-associated protein, BMA_A0400 family 9 135 2.3E-36 T 29-03-2018 IPR017748 Type VI secretion system-associated, BMAA0400 CDC59_RS19735 038aa40e3fb1f088d324070d4c086b4a 328 Pfam PF09867 Uncharacterized protein conserved in bacteria (DUF2094) 10 128 2.9E-25 T 29-03-2018 IPR017748 Type VI secretion system-associated, BMAA0400 CDC59_RS19735 038aa40e3fb1f088d324070d4c086b4a 328 Gene3D G3DSA:3.40.1730.10 6 239 5.9E-31 T 29-03-2018 CDC59_RS14395 7b9fa5eda6fa9e1f9856ebb34750afa6 289 PIRSF PIRSF006232 1 283 2.2E-89 T 29-03-2018 IPR012093 Pirin Reactome: R-HSA-8935690 CDC59_RS14395 7b9fa5eda6fa9e1f9856ebb34750afa6 289 Gene3D G3DSA:2.60.120.10 3 247 8.7E-67 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CDC59_RS14395 7b9fa5eda6fa9e1f9856ebb34750afa6 289 Pfam PF05726 Pirin C-terminal cupin domain 176 274 4.6E-27 T 29-03-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 CDC59_RS14395 7b9fa5eda6fa9e1f9856ebb34750afa6 289 SUPERFAMILY SSF51182 5 285 1.71E-81 T 29-03-2018 IPR011051 RmlC-like cupin domain CDC59_RS14395 7b9fa5eda6fa9e1f9856ebb34750afa6 289 Pfam PF02678 Pirin 18 123 2.6E-36 T 29-03-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 CDC59_RS12390 4b507cf197ab7c4069e89e1a75381ae1 303 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 9 285 6.1E-79 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CDC59_RS12390 4b507cf197ab7c4069e89e1a75381ae1 303 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 6 290 20.421 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CDC59_RS12390 4b507cf197ab7c4069e89e1a75381ae1 303 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 4 291 4.3E-86 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CDC59_RS12390 4b507cf197ab7c4069e89e1a75381ae1 303 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 141 153 - T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CDC59_RS17095 7afea71fb340b3a6e3771b7318376cf2 249 Pfam PF00813 FliP family 52 243 3.3E-76 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CDC59_RS17095 7afea71fb340b3a6e3771b7318376cf2 249 TIGRFAM TIGR01103 fliP: flagellar biosynthetic protein FliP 51 247 3.4E-87 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CDC59_RS17095 7afea71fb340b3a6e3771b7318376cf2 249 ProSitePatterns PS01061 Flagella transport protein fliP family signature 2. 224 236 - T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CDC59_RS17095 7afea71fb340b3a6e3771b7318376cf2 249 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 68 88 9.6E-65 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CDC59_RS17095 7afea71fb340b3a6e3771b7318376cf2 249 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 197 218 9.6E-65 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CDC59_RS17095 7afea71fb340b3a6e3771b7318376cf2 249 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 49 68 9.6E-65 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CDC59_RS17095 7afea71fb340b3a6e3771b7318376cf2 249 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 88 107 9.6E-65 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CDC59_RS17095 7afea71fb340b3a6e3771b7318376cf2 249 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 176 196 9.6E-65 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CDC59_RS17095 7afea71fb340b3a6e3771b7318376cf2 249 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 221 246 9.6E-65 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CDC59_RS17095 7afea71fb340b3a6e3771b7318376cf2 249 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 169 181 1.7E-28 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CDC59_RS17095 7afea71fb340b3a6e3771b7318376cf2 249 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 47 56 1.7E-28 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CDC59_RS17095 7afea71fb340b3a6e3771b7318376cf2 249 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 107 119 1.7E-28 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CDC59_RS17095 7afea71fb340b3a6e3771b7318376cf2 249 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 147 159 1.7E-28 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CDC59_RS17095 7afea71fb340b3a6e3771b7318376cf2 249 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 237 247 1.7E-28 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CDC59_RS17095 7afea71fb340b3a6e3771b7318376cf2 249 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 119 133 1.7E-28 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CDC59_RS19180 280a675eae49d9f402d80323449a18b5 68 Pfam PF03621 MbtH-like protein 7 54 6.4E-20 T 29-03-2018 IPR005153 MbtH-like protein CDC59_RS19180 280a675eae49d9f402d80323449a18b5 68 Gene3D G3DSA:3.90.820.10 4 68 5.5E-28 T 29-03-2018 CDC59_RS19180 280a675eae49d9f402d80323449a18b5 68 SMART SM00923 4 54 6.0E-17 T 29-03-2018 IPR005153 MbtH-like protein CDC59_RS19180 280a675eae49d9f402d80323449a18b5 68 SUPERFAMILY SSF160582 7 67 6.67E-25 T 29-03-2018 CDC59_RS18265 208f0614d05e2aeaaf93f01ee98291cc 346 Gene3D G3DSA:3.40.190.10 35 150 1.1E-6 T 29-03-2018 CDC59_RS18265 208f0614d05e2aeaaf93f01ee98291cc 346 Gene3D G3DSA:3.40.190.10 151 340 2.7E-17 T 29-03-2018 CDC59_RS18265 208f0614d05e2aeaaf93f01ee98291cc 346 SUPERFAMILY SSF53850 39 278 3.38E-23 T 29-03-2018 CDC59_RS18265 208f0614d05e2aeaaf93f01ee98291cc 346 Pfam PF13379 NMT1-like family 35 279 1.3E-18 T 29-03-2018 CDC59_RS04645 0d084400a193950bdca242e3367990da 370 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 6 105 2.0E-19 T 29-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CDC59_RS04645 0d084400a193950bdca242e3367990da 370 PIRSF PIRSF006769 1 367 3.1E-119 T 29-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 CDC59_RS04645 0d084400a193950bdca242e3367990da 370 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 10 360 3.1E-107 T 29-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 CDC59_RS04645 0d084400a193950bdca242e3367990da 370 Pfam PF01872 RibD C-terminal domain 153 341 1.1E-45 T 29-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CDC59_RS04645 0d084400a193950bdca242e3367990da 370 SUPERFAMILY SSF53597 151 365 6.54E-58 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CDC59_RS04645 0d084400a193950bdca242e3367990da 370 Gene3D G3DSA:3.40.140.10 3 130 9.8E-35 T 29-03-2018 CDC59_RS04645 0d084400a193950bdca242e3367990da 370 SUPERFAMILY SSF53927 6 150 1.75E-47 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CDC59_RS04645 0d084400a193950bdca242e3367990da 370 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 94 - T 29-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CDC59_RS04645 0d084400a193950bdca242e3367990da 370 Gene3D G3DSA:3.40.430.10 131 368 5.4E-69 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CDC59_RS04645 0d084400a193950bdca242e3367990da 370 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 152 363 9.2E-53 T 29-03-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 CDC59_RS14665 f5a5fb35ca5b899636b172acc1883986 229 PIRSF PIRSF016262 1 227 5.5E-54 T 29-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CDC59_RS14665 f5a5fb35ca5b899636b172acc1883986 229 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 73 126 2.0E-23 T 29-03-2018 CDC59_RS14665 f5a5fb35ca5b899636b172acc1883986 229 Hamap MF_00013 Octanoyltransferase [lipB]. 3 218 35.437 T 29-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CDC59_RS14665 f5a5fb35ca5b899636b172acc1883986 229 Pfam PF03099 Biotin/lipoate A/B protein ligase family 58 162 1.1E-5 T 29-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CDC59_RS14665 f5a5fb35ca5b899636b172acc1883986 229 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 24 185 1.9E-53 T 29-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CDC59_RS14665 f5a5fb35ca5b899636b172acc1883986 229 Gene3D G3DSA:3.30.930.10 2 228 9.2E-55 T 29-03-2018 CDC59_RS14665 f5a5fb35ca5b899636b172acc1883986 229 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 69 84 - T 29-03-2018 IPR020605 Octanoyltransferase, conserved site GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 CDC59_RS14665 f5a5fb35ca5b899636b172acc1883986 229 SUPERFAMILY SSF55681 4 191 6.88E-60 T 29-03-2018 CDC59_RS07675 ca6135248c7551129b49daca602df132 554 Gene3D G3DSA:3.40.50.880 290 548 2.0E-74 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CDC59_RS07675 ca6135248c7551129b49daca602df132 554 Gene3D G3DSA:3.40.50.300 1 289 3.8E-130 T 29-03-2018 CDC59_RS07675 ca6135248c7551129b49daca602df132 554 Pfam PF00117 Glutamine amidotransferase class-I 305 539 1.3E-54 T 29-03-2018 IPR017926 Glutamine amidotransferase CDC59_RS07675 ca6135248c7551129b49daca602df132 554 Pfam PF06418 CTP synthase N-terminus 3 270 4.7E-125 T 29-03-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CDC59_RS07675 ca6135248c7551129b49daca602df132 554 SUPERFAMILY SSF52540 2 270 3.67E-119 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS07675 ca6135248c7551129b49daca602df132 554 TIGRFAM TIGR00337 PyrG: CTP synthase 1 540 4.4E-239 T 29-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CDC59_RS07675 ca6135248c7551129b49daca602df132 554 SUPERFAMILY SSF52317 292 547 8.74E-85 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CDC59_RS07675 ca6135248c7551129b49daca602df132 554 Hamap MF_01227 CTP synthase [pyrG]. 2 545 51.094 T 29-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CDC59_RS05535 ebc5da8da3f825a9e776761789373c43 370 SUPERFAMILY SSF53955 52 367 7.31E-77 T 29-03-2018 IPR023346 Lysozyme-like domain CDC59_RS05535 ebc5da8da3f825a9e776761789373c43 370 Gene3D G3DSA:1.10.8.350 50 120 9.1E-5 T 29-03-2018 CDC59_RS05535 ebc5da8da3f825a9e776761789373c43 370 Gene3D G3DSA:1.10.8.350 121 231 1.2E-33 T 29-03-2018 CDC59_RS05535 ebc5da8da3f825a9e776761789373c43 370 TIGRFAM TIGR02282 MltB: lytic murein transglycosylase B 59 364 1.2E-120 T 29-03-2018 IPR011757 Lytic transglycosylase MltB CDC59_RS05535 ebc5da8da3f825a9e776761789373c43 370 Pfam PF13406 Transglycosylase SLT domain 56 362 1.8E-84 T 29-03-2018 IPR031304 Transglycosylase SLT domain 2 CDC59_RS05535 ebc5da8da3f825a9e776761789373c43 370 Gene3D G3DSA:1.10.530.10 237 370 8.4E-25 T 29-03-2018 CDC59_RS13970 51b1de88ec16226e49609849f9058441 138 Pfam PF06155 Protein of unknown function (DUF971) 14 98 1.4E-29 T 29-03-2018 IPR010376 Domain of unknown function DUF971 Reactome: R-HSA-71262 CDC59_RS15525 c9c527dd80fc8e167c72b278e558cd3e 507 SUPERFAMILY SSF50974 168 503 5.75E-38 T 29-03-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 CDC59_RS15525 c9c527dd80fc8e167c72b278e558cd3e 507 Gene3D G3DSA:2.130.10.10 355 505 2.7E-20 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CDC59_RS15525 c9c527dd80fc8e167c72b278e558cd3e 507 Gene3D G3DSA:2.130.10.10 108 354 2.1E-18 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CDC59_RS15525 c9c527dd80fc8e167c72b278e558cd3e 507 Pfam PF10282 Lactonase, 7-bladed beta-propeller 354 492 1.1E-17 T 29-03-2018 IPR019405 Lactonase, 7-bladed beta propeller CDC59_RS15525 c9c527dd80fc8e167c72b278e558cd3e 507 Pfam PF10282 Lactonase, 7-bladed beta-propeller 170 256 6.4E-10 T 29-03-2018 IPR019405 Lactonase, 7-bladed beta propeller CDC59_RS13295 eb62fb6f3835b50ba799a694b7079312 513 SUPERFAMILY SSF56601 57 510 1.16E-96 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CDC59_RS13295 eb62fb6f3835b50ba799a694b7079312 513 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 88 489 1.6E-59 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CDC59_RS13295 eb62fb6f3835b50ba799a694b7079312 513 Gene3D G3DSA:3.40.710.10 57 513 3.4E-37 T 29-03-2018 CDC59_RS13295 eb62fb6f3835b50ba799a694b7079312 513 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 100 119 1.9E-19 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CDC59_RS13295 eb62fb6f3835b50ba799a694b7079312 513 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 405 419 1.9E-19 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CDC59_RS13295 eb62fb6f3835b50ba799a694b7079312 513 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 467 480 1.9E-19 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CDC59_RS13295 eb62fb6f3835b50ba799a694b7079312 513 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 390 404 1.9E-19 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CDC59_RS13295 eb62fb6f3835b50ba799a694b7079312 513 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 332 354 1.9E-19 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CDC59_RS13295 eb62fb6f3835b50ba799a694b7079312 513 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 62 506 7.0E-78 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CDC59_RS12330 4d089537d65fa25352eb353059970f7d 313 Gene3D G3DSA:3.40.50.1980 138 302 4.2E-35 T 29-03-2018 CDC59_RS12330 4d089537d65fa25352eb353059970f7d 313 SUPERFAMILY SSF53807 25 293 3.41E-68 T 29-03-2018 CDC59_RS12330 4d089537d65fa25352eb353059970f7d 313 Gene3D G3DSA:3.40.50.1980 25 137 1.5E-30 T 29-03-2018 CDC59_RS12330 4d089537d65fa25352eb353059970f7d 313 Pfam PF01497 Periplasmic binding protein 47 274 3.4E-29 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CDC59_RS12160 507290f27a4c27df7aa4411a57f3da9e 472 SUPERFAMILY SSF103473 20 210 5.75E-66 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS12160 507290f27a4c27df7aa4411a57f3da9e 472 SUPERFAMILY SSF103473 263 466 5.75E-66 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS12160 507290f27a4c27df7aa4411a57f3da9e 472 Gene3D G3DSA:1.20.1250.20 20 213 1.0E-30 T 29-03-2018 CDC59_RS12160 507290f27a4c27df7aa4411a57f3da9e 472 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 30 436 2.6E-74 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CDC59_RS12160 507290f27a4c27df7aa4411a57f3da9e 472 PRINTS PR01036 Tetracycline resistance protein TetB signature 31 55 1.9E-5 T 29-03-2018 CDC59_RS12160 507290f27a4c27df7aa4411a57f3da9e 472 PRINTS PR01036 Tetracycline resistance protein TetB signature 153 177 1.9E-5 T 29-03-2018 CDC59_RS12160 507290f27a4c27df7aa4411a57f3da9e 472 PRINTS PR01036 Tetracycline resistance protein TetB signature 416 435 1.9E-5 T 29-03-2018 CDC59_RS12160 507290f27a4c27df7aa4411a57f3da9e 472 Gene3D G3DSA:1.20.1250.20 267 470 6.6E-25 T 29-03-2018 CDC59_RS12160 507290f27a4c27df7aa4411a57f3da9e 472 Pfam PF07690 Major Facilitator Superfamily 34 425 2.1E-47 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDC59_RS07015 e81edc51c63ecbcbf53cfb4c0a91e891 358 Gene3D G3DSA:1.20.1050.10 250 358 2.5E-22 T 29-03-2018 CDC59_RS07015 e81edc51c63ecbcbf53cfb4c0a91e891 358 SUPERFAMILY SSF55961 6 148 7.27E-43 T 29-03-2018 CDC59_RS07015 e81edc51c63ecbcbf53cfb4c0a91e891 358 Pfam PF13417 Glutathione S-transferase, N-terminal domain 158 228 4.3E-13 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CDC59_RS07015 e81edc51c63ecbcbf53cfb4c0a91e891 358 Gene3D G3DSA:3.30.530.20 1 153 8.8E-33 T 29-03-2018 IPR023393 START-like domain CDC59_RS07015 e81edc51c63ecbcbf53cfb4c0a91e891 358 Gene3D G3DSA:3.40.30.10 154 249 1.3E-21 T 29-03-2018 CDC59_RS07015 e81edc51c63ecbcbf53cfb4c0a91e891 358 SUPERFAMILY SSF47616 220 355 1.95E-23 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like CDC59_RS07015 e81edc51c63ecbcbf53cfb4c0a91e891 358 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 16 146 1.0E-29 T 29-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CDC59_RS07015 e81edc51c63ecbcbf53cfb4c0a91e891 358 SUPERFAMILY SSF52833 152 233 8.13E-19 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS07015 e81edc51c63ecbcbf53cfb4c0a91e891 358 Pfam PF00043 Glutathione S-transferase, C-terminal domain 268 341 4.9E-11 T 29-03-2018 IPR004046 Glutathione S-transferase, C-terminal CDC59_RS14425 2d911d8a2e22fb8bd68f5cf7a8d0a046 363 Pfam PF02628 Cytochrome oxidase assembly protein 31 341 2.4E-89 T 29-03-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 CDC59_RS01145 8300a0e68ff6bb4056a688575a4e0f3d 235 Pfam PF03330 Lytic transglycolase 96 184 6.1E-23 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CDC59_RS01145 8300a0e68ff6bb4056a688575a4e0f3d 235 Gene3D G3DSA:2.40.40.10 82 190 4.8E-21 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CDC59_RS01145 8300a0e68ff6bb4056a688575a4e0f3d 235 SUPERFAMILY SSF50685 97 185 1.57E-9 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CDC59_RS01145 8300a0e68ff6bb4056a688575a4e0f3d 235 Hamap MF_02071 Endolytic peptidoglycan transglycosylase RlpA [rlpA]. 12 188 22.655 T 29-03-2018 IPR034718 Endolytic peptidoglycan transglycosylase RlpA GO:0016829 CDC59_RS01145 8300a0e68ff6bb4056a688575a4e0f3d 235 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 98 203 8.4E-39 T 29-03-2018 IPR012997 Rare lipoprotein A CDC59_RS09160 cbb9be2a5f5f283fc3461fdfaa4b7ede 236 Gene3D G3DSA:3.40.1160.10 1 236 6.4E-43 T 29-03-2018 CDC59_RS09160 cbb9be2a5f5f283fc3461fdfaa4b7ede 236 SUPERFAMILY SSF53633 2 235 4.58E-72 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CDC59_RS09160 cbb9be2a5f5f283fc3461fdfaa4b7ede 236 Hamap MF_01220_B Uridylate kinase [pyrH]. 2 235 44.477 T 29-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 CDC59_RS09160 cbb9be2a5f5f283fc3461fdfaa4b7ede 236 PIRSF PIRSF005650 1 236 1.7E-93 T 29-03-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 CDC59_RS09160 cbb9be2a5f5f283fc3461fdfaa4b7ede 236 Pfam PF00696 Amino acid kinase family 5 214 1.6E-29 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CDC59_RS09160 cbb9be2a5f5f283fc3461fdfaa4b7ede 236 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 4 235 1.1E-101 T 29-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 CDC59_RS08740 35d43b4026cdd6a688e5c0229f271b6a 386 Gene3D G3DSA:3.40.640.10 1 246 1.6E-47 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDC59_RS08740 35d43b4026cdd6a688e5c0229f271b6a 386 SUPERFAMILY SSF53383 12 382 1.13E-104 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS08740 35d43b4026cdd6a688e5c0229f271b6a 386 Gene3D G3DSA:3.90.1150.10 247 386 7.9E-37 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS08740 35d43b4026cdd6a688e5c0229f271b6a 386 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 20 378 1.6E-111 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CDC59_RS08740 35d43b4026cdd6a688e5c0229f271b6a 386 PIRSF PIRSF000390 10 386 1.9E-102 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CDC59_RS00890 1ab5b893918d5ad3b7e5546b2c8a3260 202 Pfam PF00043 Glutathione S-transferase, C-terminal domain 102 189 1.6E-12 T 29-03-2018 IPR004046 Glutathione S-transferase, C-terminal CDC59_RS00890 1ab5b893918d5ad3b7e5546b2c8a3260 202 Gene3D G3DSA:3.40.30.10 1 98 5.8E-16 T 29-03-2018 CDC59_RS00890 1ab5b893918d5ad3b7e5546b2c8a3260 202 SUPERFAMILY SSF47616 82 198 2.05E-25 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like CDC59_RS00890 1ab5b893918d5ad3b7e5546b2c8a3260 202 Gene3D G3DSA:1.20.1050.10 99 200 1.9E-23 T 29-03-2018 CDC59_RS00890 1ab5b893918d5ad3b7e5546b2c8a3260 202 SUPERFAMILY SSF52833 1 77 1.07E-14 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS22155 9fef05c12515250d6305af5408e598a9 140 Pfam PF13564 DoxX-like family 23 128 7.7E-23 T 29-03-2018 IPR032808 DoxX family CDC59_RS17165 50c718b646bb08d9eb0d144d676ec315 462 SUPERFAMILY SSF53448 1 206 2.67E-37 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDC59_RS17165 50c718b646bb08d9eb0d144d676ec315 462 SUPERFAMILY SSF53335 289 449 3.01E-9 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS17165 50c718b646bb08d9eb0d144d676ec315 462 Gene3D G3DSA:3.40.50.150 194 389 2.7E-6 T 29-03-2018 CDC59_RS17165 50c718b646bb08d9eb0d144d676ec315 462 Pfam PF04488 Glycosyltransferase sugar-binding region containing DXD motif 19 97 1.4E-6 T 29-03-2018 IPR007577 Glycosyltransferase, DXD sugar-binding motif CDC59_RS12340 98cf5aa6c588cb4d65720b1837ca609c 258 Pfam PF02654 Cobalamin-5-phosphate synthase 15 249 1.2E-51 T 29-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CDC59_RS12340 98cf5aa6c588cb4d65720b1837ca609c 258 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 258 51.46 T 29-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CDC59_RS12340 98cf5aa6c588cb4d65720b1837ca609c 258 TIGRFAM TIGR00317 cobS: cobalamin 5'-phosphate synthase 10 250 9.5E-35 T 29-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CDC59_RS09745 a65d31c43d96441ceb6d8aaebbbd8d25 336 Pfam PF00107 Zinc-binding dehydrogenase 158 293 1.1E-22 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CDC59_RS09745 a65d31c43d96441ceb6d8aaebbbd8d25 336 Gene3D G3DSA:3.90.180.10 1 148 5.5E-37 T 29-03-2018 CDC59_RS09745 a65d31c43d96441ceb6d8aaebbbd8d25 336 Gene3D G3DSA:3.40.50.720 149 277 1.5E-29 T 29-03-2018 CDC59_RS09745 a65d31c43d96441ceb6d8aaebbbd8d25 336 Pfam PF16884 N-terminal domain of oxidoreductase 7 113 3.6E-42 T 29-03-2018 CDC59_RS09745 a65d31c43d96441ceb6d8aaebbbd8d25 336 SUPERFAMILY SSF51735 123 301 1.22E-48 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS09745 a65d31c43d96441ceb6d8aaebbbd8d25 336 SUPERFAMILY SSF50129 2 164 1.11E-46 T 29-03-2018 IPR011032 GroES-like CDC59_RS09745 a65d31c43d96441ceb6d8aaebbbd8d25 336 SMART SM00829 18 333 2.3E-7 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CDC59_RS11935 f17a1755421ceaf1132881a21c4acd14 194 SUPERFAMILY SSF102405 1 177 6.11E-64 T 29-03-2018 CDC59_RS11935 f17a1755421ceaf1132881a21c4acd14 194 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 2 175 1.9E-66 T 29-03-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG CDC59_RS11935 f17a1755421ceaf1132881a21c4acd14 194 Pfam PF03641 Possible lysine decarboxylase 46 174 8.8E-45 T 29-03-2018 IPR031100 LOG family CDC59_RS11935 f17a1755421ceaf1132881a21c4acd14 194 Gene3D G3DSA:3.40.50.450 1 194 8.4E-65 T 29-03-2018 CDC59_RS00490 1ef80182802984d9039f105e35a1b05d 144 Gene3D G3DSA:3.10.129.10 2 144 2.0E-29 T 29-03-2018 CDC59_RS00490 1ef80182802984d9039f105e35a1b05d 144 Pfam PF03061 Thioesterase superfamily 56 132 6.2E-11 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CDC59_RS00490 1ef80182802984d9039f105e35a1b05d 144 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 31 141 1.8E-19 T 29-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 CDC59_RS00490 1ef80182802984d9039f105e35a1b05d 144 SUPERFAMILY SSF54637 6 140 2.44E-35 T 29-03-2018 IPR029069 HotDog domain CDC59_RS08345 56048fb2ba16472809bc8d9efd7edd93 319 TIGRFAM TIGR04379 myo_inos_iolE: myo-inosose-2 dehydratase 13 306 9.5E-115 T 29-03-2018 IPR030823 IolE/MocC family KEGG: 00562+4.2.1.44 CDC59_RS08345 56048fb2ba16472809bc8d9efd7edd93 319 SUPERFAMILY SSF51658 14 308 1.8E-57 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CDC59_RS08345 56048fb2ba16472809bc8d9efd7edd93 319 Pfam PF01261 Xylose isomerase-like TIM barrel 41 246 2.4E-22 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CDC59_RS08345 56048fb2ba16472809bc8d9efd7edd93 319 Gene3D G3DSA:3.20.20.150 8 311 1.6E-53 T 29-03-2018 CDC59_RS12545 a8633978f6ca9cc0768b276abe6a333d 311 Gene3D G3DSA:1.10.3470.10 1 300 2.5E-55 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CDC59_RS12545 a8633978f6ca9cc0768b276abe6a333d 311 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 295 4.0E-49 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CDC59_RS20800 020e80282bccabdac7b8c99775aa434c 417 Gene3D G3DSA:3.40.50.2000 1 213 1.2E-20 T 29-03-2018 CDC59_RS20800 020e80282bccabdac7b8c99775aa434c 417 SUPERFAMILY SSF53756 2 401 5.1E-58 T 29-03-2018 CDC59_RS20800 020e80282bccabdac7b8c99775aa434c 417 Pfam PF13579 Glycosyl transferase 4-like domain 16 198 2.3E-24 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CDC59_RS20800 020e80282bccabdac7b8c99775aa434c 417 Pfam PF13692 Glycosyl transferases group 1 224 366 8.4E-15 T 29-03-2018 CDC59_RS20800 020e80282bccabdac7b8c99775aa434c 417 Gene3D G3DSA:3.40.50.2000 214 387 3.9E-30 T 29-03-2018 CDC59_RS18495 033d4897726ee767076f2ed83d4ab903 292 SUPERFAMILY SSF53850 92 283 7.84E-30 T 29-03-2018 CDC59_RS18495 033d4897726ee767076f2ed83d4ab903 292 SUPERFAMILY SSF46785 6 114 3.73E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS18495 033d4897726ee767076f2ed83d4ab903 292 Pfam PF03466 LysR substrate binding domain 92 279 2.1E-27 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS18495 033d4897726ee767076f2ed83d4ab903 292 Gene3D G3DSA:1.10.10.10 1 88 4.5E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS18495 033d4897726ee767076f2ed83d4ab903 292 Gene3D G3DSA:3.40.190.10 177 256 3.1E-12 T 29-03-2018 CDC59_RS18495 033d4897726ee767076f2ed83d4ab903 292 Gene3D G3DSA:3.40.190.10 94 176 6.5E-18 T 29-03-2018 CDC59_RS18495 033d4897726ee767076f2ed83d4ab903 292 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 66 9.5E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS18495 033d4897726ee767076f2ed83d4ab903 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 5.1E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS18495 033d4897726ee767076f2ed83d4ab903 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 5.1E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS18495 033d4897726ee767076f2ed83d4ab903 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 5.1E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS18560 c7e942caa7d61bcc8508f83027d53207 1432 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 742 781 1.8E-4 T 29-03-2018 IPR006530 YD repeat CDC59_RS18560 c7e942caa7d61bcc8508f83027d53207 1432 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 577 613 2.0E-4 T 29-03-2018 IPR006530 YD repeat CDC59_RS18560 c7e942caa7d61bcc8508f83027d53207 1432 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 722 750 0.0015 T 29-03-2018 IPR006530 YD repeat CDC59_RS18560 c7e942caa7d61bcc8508f83027d53207 1432 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 529 569 5.2E-8 T 29-03-2018 IPR006530 YD repeat CDC59_RS18560 c7e942caa7d61bcc8508f83027d53207 1432 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 637 677 1.0E-6 T 29-03-2018 IPR006530 YD repeat CDC59_RS18560 c7e942caa7d61bcc8508f83027d53207 1432 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1085 1122 0.0031 T 29-03-2018 IPR006530 YD repeat CDC59_RS18560 c7e942caa7d61bcc8508f83027d53207 1432 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1219 1298 1.8E-23 T 29-03-2018 IPR022385 Rhs repeat-associated core GO:0097264 CDC59_RS18560 c7e942caa7d61bcc8508f83027d53207 1432 Pfam PF03527 RHS protein 1193 1227 6.0E-13 T 29-03-2018 IPR001826 RHS protein CDC59_RS18560 c7e942caa7d61bcc8508f83027d53207 1432 Gene3D G3DSA:2.130.10.10 264 1124 0.0089 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CDC59_RS18560 c7e942caa7d61bcc8508f83027d53207 1432 Pfam PF14412 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH 1311 1389 3.0E-10 T 29-03-2018 IPR032871 AHH domain-containing protein CDC59_RS18560 c7e942caa7d61bcc8508f83027d53207 1432 Pfam PF05593 RHS Repeat 550 587 5.3E-6 T 29-03-2018 IPR031325 RHS repeat CDC59_RS18560 c7e942caa7d61bcc8508f83027d53207 1432 Pfam PF05593 RHS Repeat 642 672 7.1E-5 T 29-03-2018 IPR031325 RHS repeat CDC59_RS18560 c7e942caa7d61bcc8508f83027d53207 1432 Pfam PF05593 RHS Repeat 421 456 2.4E-5 T 29-03-2018 IPR031325 RHS repeat CDC59_RS18560 c7e942caa7d61bcc8508f83027d53207 1432 Pfam PF05593 RHS Repeat 529 566 4.0E-7 T 29-03-2018 IPR031325 RHS repeat CDC59_RS18560 c7e942caa7d61bcc8508f83027d53207 1432 Pfam PF05488 PAAR motif 74 141 2.4E-16 T 29-03-2018 IPR008727 PAAR motif CDC59_RS06425 03631ccec38783afc075b5e7ac5e1995 201 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 2 197 47.273 T 29-03-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 CDC59_RS06425 03631ccec38783afc075b5e7ac5e1995 201 Pfam PF01725 Ham1 family 4 193 7.4E-54 T 29-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 CDC59_RS06425 03631ccec38783afc075b5e7ac5e1995 201 SUPERFAMILY SSF52972 2 195 4.45E-67 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CDC59_RS06425 03631ccec38783afc075b5e7ac5e1995 201 Gene3D G3DSA:3.90.950.10 1 200 4.6E-73 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CDC59_RS06425 03631ccec38783afc075b5e7ac5e1995 201 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 4 195 4.0E-52 T 29-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 CDC59_RS11375 c6d0781b0ac4697482ab93e59b7dcaaf 273 TIGRFAM TIGR01291 nodJ: ABC-2 type transporter, NodJ family 23 271 4.7E-92 T 29-03-2018 IPR005981 ABC-2 type transporter, NodJ GO:0005215|GO:0009877|GO:0015772|GO:0016020 CDC59_RS11375 c6d0781b0ac4697482ab93e59b7dcaaf 273 Pfam PF01061 ABC-2 type transporter 27 237 4.0E-24 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CDC59_RS11375 c6d0781b0ac4697482ab93e59b7dcaaf 273 PIRSF PIRSF006648 2 272 2.2E-25 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CDC59_RS11375 c6d0781b0ac4697482ab93e59b7dcaaf 273 PRINTS PR00164 ABC-2 type transport system membrane protein signature 46 67 5.7E-51 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CDC59_RS11375 c6d0781b0ac4697482ab93e59b7dcaaf 273 PRINTS PR00164 ABC-2 type transport system membrane protein signature 76 98 5.7E-51 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CDC59_RS11375 c6d0781b0ac4697482ab93e59b7dcaaf 273 PRINTS PR00164 ABC-2 type transport system membrane protein signature 158 182 5.7E-51 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CDC59_RS11375 c6d0781b0ac4697482ab93e59b7dcaaf 273 PRINTS PR00164 ABC-2 type transport system membrane protein signature 121 146 5.7E-51 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CDC59_RS11375 c6d0781b0ac4697482ab93e59b7dcaaf 273 PRINTS PR00164 ABC-2 type transport system membrane protein signature 215 234 5.7E-51 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CDC59_RS11375 c6d0781b0ac4697482ab93e59b7dcaaf 273 PRINTS PR00164 ABC-2 type transport system membrane protein signature 195 214 5.7E-51 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CDC59_RS13515 20944a39d97bc3724500d7e22daf0499 549 Hamap MF_00968 ATP-dependent RNA helicase RhlE [rhlE]. 1 515 51.82 T 29-03-2018 IPR028622 ATP-dependent RNA helicase RhlE GO:0004004|GO:0042255 CDC59_RS13515 20944a39d97bc3724500d7e22daf0499 549 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 159 167 - T 29-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site CDC59_RS13515 20944a39d97bc3724500d7e22daf0499 549 Pfam PF00270 DEAD/DEAH box helicase 25 200 4.3E-48 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CDC59_RS13515 20944a39d97bc3724500d7e22daf0499 549 Gene3D G3DSA:3.40.50.300 8 228 7.7E-61 T 29-03-2018 CDC59_RS13515 20944a39d97bc3724500d7e22daf0499 549 SMART SM00490 264 345 6.8E-33 T 29-03-2018 IPR001650 Helicase, C-terminal CDC59_RS13515 20944a39d97bc3724500d7e22daf0499 549 SMART SM00487 20 228 8.4E-62 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CDC59_RS13515 20944a39d97bc3724500d7e22daf0499 549 Pfam PF00271 Helicase conserved C-terminal domain 239 345 9.0E-28 T 29-03-2018 IPR001650 Helicase, C-terminal CDC59_RS13515 20944a39d97bc3724500d7e22daf0499 549 SUPERFAMILY SSF52540 81 366 1.55E-76 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS13515 20944a39d97bc3724500d7e22daf0499 549 Gene3D G3DSA:3.40.50.300 229 538 8.1E-49 T 29-03-2018 CDC59_RS05935 020f44123de0df700e2753db1ef980ab 230 SUPERFAMILY SSF161098 21 208 2.49E-40 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS05935 020f44123de0df700e2753db1ef980ab 230 Gene3D G3DSA:1.10.3720.10 9 228 1.4E-40 T 29-03-2018 CDC59_RS05935 020f44123de0df700e2753db1ef980ab 230 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 23 116 6.4E-25 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CDC59_RS05935 020f44123de0df700e2753db1ef980ab 230 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 40 222 7.4E-16 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS09020 c560f9b2278eb556d5c2c08f599343d2 517 Gene3D G3DSA:3.90.76.10 40 184 3.8E-39 T 29-03-2018 CDC59_RS09020 c560f9b2278eb556d5c2c08f599343d2 517 PIRSF PIRSF002741 20 517 1.5E-111 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CDC59_RS09020 c560f9b2278eb556d5c2c08f599343d2 517 Gene3D G3DSA:3.40.190.10 185 277 8.6E-26 T 29-03-2018 CDC59_RS09020 c560f9b2278eb556d5c2c08f599343d2 517 SUPERFAMILY SSF53850 34 515 2.44E-140 T 29-03-2018 CDC59_RS09020 c560f9b2278eb556d5c2c08f599343d2 517 Gene3D G3DSA:3.10.105.10 278 490 3.2E-55 T 29-03-2018 CDC59_RS09020 c560f9b2278eb556d5c2c08f599343d2 517 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 73 431 1.1E-94 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CDC59_RS00840 ae8f466af78438d6b9057a1b2cd0c162 513 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 3 511 1.1E-249 T 29-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS00840 ae8f466af78438d6b9057a1b2cd0c162 513 PIRSF PIRSF039088 1 513 1.8E-240 T 29-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS00840 ae8f466af78438d6b9057a1b2cd0c162 513 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 27 92 3.3E-16 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CDC59_RS00840 ae8f466af78438d6b9057a1b2cd0c162 513 Gene3D G3DSA:2.40.30.20 3 82 3.9E-34 T 29-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS00840 ae8f466af78438d6b9057a1b2cd0c162 513 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 375 2.4E-73 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CDC59_RS00840 ae8f466af78438d6b9057a1b2cd0c162 513 SUPERFAMILY SSF47917 383 510 3.14E-47 T 29-03-2018 CDC59_RS00840 ae8f466af78438d6b9057a1b2cd0c162 513 SUPERFAMILY SSF52540 96 381 2.25E-94 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS00840 ae8f466af78438d6b9057a1b2cd0c162 513 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 512 50.427 T 29-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS00840 ae8f466af78438d6b9057a1b2cd0c162 513 Gene3D G3DSA:1.20.150.20 384 510 7.3E-48 T 29-03-2018 CDC59_RS00840 ae8f466af78438d6b9057a1b2cd0c162 513 SUPERFAMILY SSF50615 10 94 5.3E-29 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CDC59_RS00840 ae8f466af78438d6b9057a1b2cd0c162 513 Gene3D G3DSA:3.40.50.300 83 375 9.6E-116 T 29-03-2018 CDC59_RS00840 ae8f466af78438d6b9057a1b2cd0c162 513 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 366 375 - T 29-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CDC59_RS00840 ae8f466af78438d6b9057a1b2cd0c162 513 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 382 507 1.3E-45 T 29-03-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS19925 4998d3d3d64125082edc4c01ca32e374 187 Pfam PF13689 Domain of unknown function (DUF4154) 46 184 2.2E-35 T 29-03-2018 IPR025293 Protein of unknown function DUF4154 CDC59_RS12440 95f28a288c87b5ffddfaf657eb7550d5 269 SUPERFAMILY SSF53790 7 252 2.09E-62 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CDC59_RS12440 95f28a288c87b5ffddfaf657eb7550d5 269 Gene3D G3DSA:3.40.1010.10 10 134 1.2E-31 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CDC59_RS12440 95f28a288c87b5ffddfaf657eb7550d5 269 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 11 249 2.8E-88 T 29-03-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CDC59_RS12440 95f28a288c87b5ffddfaf657eb7550d5 269 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 16 30 - T 29-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CDC59_RS12440 95f28a288c87b5ffddfaf657eb7550d5 269 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 90 123 - T 29-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CDC59_RS12440 95f28a288c87b5ffddfaf657eb7550d5 269 Gene3D G3DSA:3.30.950.10 135 269 1.5E-24 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CDC59_RS12440 95f28a288c87b5ffddfaf657eb7550d5 269 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 13 225 1.1E-43 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CDC59_RS09270 c551c8a9d6e34340c65d4603cd80ed8f 145 SUPERFAMILY SSF55961 1 143 4.84E-33 T 29-03-2018 CDC59_RS09270 c551c8a9d6e34340c65d4603cd80ed8f 145 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 10 134 2.2E-29 T 29-03-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 CDC59_RS09270 c551c8a9d6e34340c65d4603cd80ed8f 145 Gene3D G3DSA:3.30.530.20 1 144 2.2E-28 T 29-03-2018 IPR023393 START-like domain CDC59_RS11735 f8ed30210d30b585c31589d9a91bf921 205 SUPERFAMILY SSF55811 30 194 1.19E-45 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CDC59_RS11735 f8ed30210d30b585c31589d9a91bf921 205 Pfam PF00293 NUDIX domain 63 171 9.6E-15 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CDC59_RS11735 f8ed30210d30b585c31589d9a91bf921 205 Gene3D G3DSA:3.90.79.10 11 199 1.9E-35 T 29-03-2018 CDC59_RS07815 77cdfb5bfe0507c16f11cafd5e037748 400 Gene3D G3DSA:1.20.1250.20 192 379 1.2E-19 T 29-03-2018 CDC59_RS07815 77cdfb5bfe0507c16f11cafd5e037748 400 Gene3D G3DSA:1.20.1250.20 3 191 3.6E-25 T 29-03-2018 CDC59_RS07815 77cdfb5bfe0507c16f11cafd5e037748 400 Pfam PF07690 Major Facilitator Superfamily 9 319 2.6E-37 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDC59_RS07815 77cdfb5bfe0507c16f11cafd5e037748 400 SUPERFAMILY SSF103473 3 379 9.02E-60 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS09775 a05d0d1bbb8bc8a8175892d031e2d6ee 322 ProSitePatterns PS01173 Lipolytic enzymes "G-D-X-G" family, putative histidine active site. 84 100 - T 29-03-2018 IPR002168 Lipase, GDXG, putative histidine active site GO:0008152|GO:0016787 Reactome: R-HSA-163560 CDC59_RS09775 a05d0d1bbb8bc8a8175892d031e2d6ee 322 Pfam PF07859 alpha/beta hydrolase fold 84 293 9.9E-77 T 29-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CDC59_RS09775 a05d0d1bbb8bc8a8175892d031e2d6ee 322 Gene3D G3DSA:3.40.50.1820 1 322 2.2E-55 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS09775 a05d0d1bbb8bc8a8175892d031e2d6ee 322 SUPERFAMILY SSF53474 30 318 3.63E-66 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS20905 e0edf67f170a6351f6dbb9ee5bcc7c02 607 SUPERFAMILY SSF52540 338 581 2.4E-84 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS20905 e0edf67f170a6351f6dbb9ee5bcc7c02 607 SUPERFAMILY SSF90123 18 330 1.09E-45 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CDC59_RS20905 e0edf67f170a6351f6dbb9ee5bcc7c02 607 SMART SM00382 372 564 2.1E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS20905 e0edf67f170a6351f6dbb9ee5bcc7c02 607 Pfam PF00005 ABC transporter 363 512 3.7E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS20905 e0edf67f170a6351f6dbb9ee5bcc7c02 607 Pfam PF00664 ABC transporter transmembrane region 65 288 1.6E-18 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CDC59_RS20905 e0edf67f170a6351f6dbb9ee5bcc7c02 607 Gene3D G3DSA:3.40.50.300 334 588 2.9E-68 T 29-03-2018 CDC59_RS20905 e0edf67f170a6351f6dbb9ee5bcc7c02 607 ProSitePatterns PS00211 ABC transporters family signature. 484 498 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS20905 e0edf67f170a6351f6dbb9ee5bcc7c02 607 Gene3D G3DSA:1.20.1560.10 15 333 7.4E-38 T 29-03-2018 CDC59_RS21545 24a82456cbf089c0b88ecfc97b9eb90f 481 SMART SM00086 360 402 1.7E-8 T 29-03-2018 IPR001610 PAC motif CDC59_RS21545 24a82456cbf089c0b88ecfc97b9eb90f 481 SUPERFAMILY SSF55785 290 402 8.03E-22 T 29-03-2018 IPR000014 PAS domain CDC59_RS21545 24a82456cbf089c0b88ecfc97b9eb90f 481 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 285 403 3.7E-12 T 29-03-2018 IPR000014 PAS domain CDC59_RS21545 24a82456cbf089c0b88ecfc97b9eb90f 481 Pfam PF08447 PAS fold 309 395 3.4E-20 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 CDC59_RS21545 24a82456cbf089c0b88ecfc97b9eb90f 481 Gene3D G3DSA:3.30.450.20 243 409 1.7E-28 T 29-03-2018 CDC59_RS21545 24a82456cbf089c0b88ecfc97b9eb90f 481 SMART SM00091 285 353 0.0011 T 29-03-2018 IPR000014 PAS domain CDC59_RS18990 f2d0f7c6e54bec7bf1a99c4f4eb341c6 110 Pfam PF10084 Uncharacterized protein conserved in bacteria (DUF2322) 8 105 4.0E-41 T 29-03-2018 IPR016755 Uncharacterised conserved protein UCP019302 CDC59_RS18990 f2d0f7c6e54bec7bf1a99c4f4eb341c6 110 PIRSF PIRSF019302 6 110 1.8E-46 T 29-03-2018 IPR016755 Uncharacterised conserved protein UCP019302 CDC59_RS15840 6d79eda7598a1fc04fe9f384b18157b8 99 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 20 94 6.8E-17 T 29-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CDC59_RS15840 6d79eda7598a1fc04fe9f384b18157b8 99 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 2 99 22.15 T 29-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CDC59_RS15840 6d79eda7598a1fc04fe9f384b18157b8 99 SUPERFAMILY SSF141000 5 97 2.48E-25 T 29-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CDC59_RS15840 6d79eda7598a1fc04fe9f384b18157b8 99 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 99 5.7E-33 T 29-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CDC59_RS06250 fd1a3c2306a3c04beb97c1c433778a38 489 SMART SM00316 37 119 3.6E-6 T 29-03-2018 IPR022967 RNA-binding domain, S1 CDC59_RS06250 fd1a3c2306a3c04beb97c1c433778a38 489 SUPERFAMILY SSF50249 39 125 1.71E-18 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDC59_RS06250 fd1a3c2306a3c04beb97c1c433778a38 489 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 425 7.3E-154 T 29-03-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 CDC59_RS06250 fd1a3c2306a3c04beb97c1c433778a38 489 Pfam PF10150 Ribonuclease E/G family 121 392 1.5E-102 T 29-03-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 CDC59_RS06250 fd1a3c2306a3c04beb97c1c433778a38 489 Gene3D G3DSA:2.40.50.140 33 124 2.9E-28 T 29-03-2018 CDC59_RS06410 2191090a0b6c2be7fd551696183c4323 210 Gene3D G3DSA:1.20.5.320 101 206 1.8E-5 T 29-03-2018 CDC59_RS06410 2191090a0b6c2be7fd551696183c4323 210 Pfam PF11180 Protein of unknown function (DUF2968) 26 202 1.1E-56 T 29-03-2018 IPR021350 Protein of unknown function DUF2968 CDC59_RS10255 a9907a7e5550f36c2885b0bddaaf633e 175 Gene3D G3DSA:1.20.1290.10 2 175 2.3E-30 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CDC59_RS10255 a9907a7e5550f36c2885b0bddaaf633e 175 Hamap MF_01676 Alkyl hydroperoxide reductase AhpD [ahpD]. 1 175 71.626 T 29-03-2018 IPR004674 Alkylhydroperoxidase AhpD GO:0006979|GO:0032843|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CDC59_RS10255 a9907a7e5550f36c2885b0bddaaf633e 175 Pfam PF02627 Carboxymuconolactone decarboxylase family 100 172 1.0E-11 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CDC59_RS10255 a9907a7e5550f36c2885b0bddaaf633e 175 SUPERFAMILY SSF69118 3 173 8.77E-38 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CDC59_RS21600 d0116a6b056970d8674fe89494d387e2 314 Gene3D G3DSA:3.40.190.10 92 176 1.0E-19 T 29-03-2018 CDC59_RS21600 d0116a6b056970d8674fe89494d387e2 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 3.5E-15 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS21600 d0116a6b056970d8674fe89494d387e2 314 Pfam PF03466 LysR substrate binding domain 88 292 3.6E-45 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS21600 d0116a6b056970d8674fe89494d387e2 314 SUPERFAMILY SSF53850 89 298 2.17E-49 T 29-03-2018 CDC59_RS21600 d0116a6b056970d8674fe89494d387e2 314 Gene3D G3DSA:1.10.10.10 3 90 1.8E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS21600 d0116a6b056970d8674fe89494d387e2 314 SUPERFAMILY SSF46785 4 85 2.51E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS21600 d0116a6b056970d8674fe89494d387e2 314 Gene3D G3DSA:3.40.190.10 177 265 4.2E-26 T 29-03-2018 CDC59_RS08625 62ea18ba24a6f412a03ba07adaa98a7e 130 SUPERFAMILY SSF54427 13 126 1.46E-12 T 29-03-2018 IPR032710 NTF2-like domain CDC59_RS08625 62ea18ba24a6f412a03ba07adaa98a7e 130 Pfam PF14534 Domain of unknown function (DUF4440) 28 119 3.7E-6 T 29-03-2018 IPR027843 Domain of unknown function DUF4440 CDC59_RS08625 62ea18ba24a6f412a03ba07adaa98a7e 130 Gene3D G3DSA:3.10.450.50 12 126 7.1E-28 T 29-03-2018 CDC59_RS21825 96ab25523d034ba0a54377ea85173013 425 Pfam PF14031 Putative serine dehydratase domain 313 410 4.5E-17 T 29-03-2018 IPR026956 D-serine dehydratase-like domain CDC59_RS21825 96ab25523d034ba0a54377ea85173013 425 SMART SM01119 313 412 5.5E-40 T 29-03-2018 IPR026956 D-serine dehydratase-like domain CDC59_RS21825 96ab25523d034ba0a54377ea85173013 425 Gene3D G3DSA:3.20.20.10 31 297 1.4E-36 T 29-03-2018 IPR029066 PLP-binding barrel CDC59_RS21825 96ab25523d034ba0a54377ea85173013 425 SUPERFAMILY SSF51419 55 290 1.78E-27 T 29-03-2018 IPR029066 PLP-binding barrel CDC59_RS21825 96ab25523d034ba0a54377ea85173013 425 Pfam PF01168 Alanine racemase, N-terminal domain 53 259 5.3E-14 T 29-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CDC59_RS19755 456eab5dce98b1c07e09a049e7f1be3d 282 Gene3D G3DSA:3.30.1380.10 148 271 7.1E-18 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CDC59_RS19755 456eab5dce98b1c07e09a049e7f1be3d 282 SUPERFAMILY SSF55166 153 272 2.62E-20 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CDC59_RS19755 456eab5dce98b1c07e09a049e7f1be3d 282 Pfam PF13539 D-alanyl-D-alanine carboxypeptidase 206 271 3.4E-11 T 29-03-2018 CDC59_RS01300 4af865b8ab0da66b879186d3f4811e9c 208 Gene3D G3DSA:1.20.1590.10 13 204 5.5E-27 T 29-03-2018 IPR023381 YP001051499.1-like domain CDC59_RS01300 4af865b8ab0da66b879186d3f4811e9c 208 Pfam PF04222 Protein of unknown function (DUF416) 18 198 2.3E-15 T 29-03-2018 IPR007338 Protein of unknown function DUF416 CDC59_RS06035 d63be26907cc8803a9b900999177420b 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 71 6.8E-32 T 29-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CDC59_RS06035 d63be26907cc8803a9b900999177420b 72 Gene3D G3DSA:2.40.50.140 1 72 7.1E-35 T 29-03-2018 CDC59_RS06035 d63be26907cc8803a9b900999177420b 72 SUPERFAMILY SSF50249 1 71 8.0E-26 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDC59_RS06035 d63be26907cc8803a9b900999177420b 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 1.4E-24 T 29-03-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 CDC59_RS06035 d63be26907cc8803a9b900999177420b 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 25.973 T 29-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CDC59_RS06035 d63be26907cc8803a9b900999177420b 72 SMART SM00316 4 72 0.0026 T 29-03-2018 IPR022967 RNA-binding domain, S1 CDC59_RS10075 985ca31db623c493fdf8fc28771e979c 278 SUPERFAMILY SSF161098 17 271 6.41E-57 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS10075 985ca31db623c493fdf8fc28771e979c 278 Gene3D G3DSA:1.10.3720.10 17 277 2.7E-42 T 29-03-2018 CDC59_RS10075 985ca31db623c493fdf8fc28771e979c 278 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 267 8.1E-17 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS03990 80ab3a2b20a8c95dc315b14c2311af95 289 Gene3D G3DSA:3.60.110.10 8 288 2.6E-77 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CDC59_RS03990 80ab3a2b20a8c95dc315b14c2311af95 289 Pfam PF00795 Carbon-nitrogen hydrolase 24 279 7.0E-52 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CDC59_RS03990 80ab3a2b20a8c95dc315b14c2311af95 289 SUPERFAMILY SSF56317 22 287 3.14E-80 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CDC59_RS09885 1ea3f31c8f2c191f2068308f1de105fd 222 Pfam PF13417 Glutathione S-transferase, N-terminal domain 17 85 1.8E-8 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CDC59_RS09885 1ea3f31c8f2c191f2068308f1de105fd 222 Pfam PF13410 Glutathione S-transferase, C-terminal domain 132 207 2.1E-8 T 29-03-2018 CDC59_RS09885 1ea3f31c8f2c191f2068308f1de105fd 222 Gene3D G3DSA:1.20.1050.10 103 210 8.6E-21 T 29-03-2018 CDC59_RS09885 1ea3f31c8f2c191f2068308f1de105fd 222 SUPERFAMILY SSF47616 89 207 9.52E-21 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like CDC59_RS09885 1ea3f31c8f2c191f2068308f1de105fd 222 SUPERFAMILY SSF52833 12 97 5.38E-17 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS09885 1ea3f31c8f2c191f2068308f1de105fd 222 Gene3D G3DSA:3.40.30.10 1 102 1.5E-20 T 29-03-2018 CDC59_RS20450 f0892fb5f07a46aff0489bfceadae6fb 219 SUPERFAMILY SSF50891 90 214 7.59E-37 T 29-03-2018 IPR029000 Cyclophilin-like domain CDC59_RS20450 f0892fb5f07a46aff0489bfceadae6fb 219 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 8 204 6.6E-57 T 29-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D CDC59_RS20450 f0892fb5f07a46aff0489bfceadae6fb 219 SUPERFAMILY SSF160467 8 95 1.05E-9 T 29-03-2018 CDC59_RS20450 f0892fb5f07a46aff0489bfceadae6fb 219 Gene3D G3DSA:3.30.1360.40 3 84 1.2E-7 T 29-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CDC59_RS20450 f0892fb5f07a46aff0489bfceadae6fb 219 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 11 212 4.9E-56 T 29-03-2018 IPR010016 KipI family CDC59_RS20450 f0892fb5f07a46aff0489bfceadae6fb 219 Gene3D G3DSA:2.40.100.10 88 217 7.7E-38 T 29-03-2018 IPR029000 Cyclophilin-like domain CDC59_RS20450 f0892fb5f07a46aff0489bfceadae6fb 219 SMART SM00796 6 204 3.5E-83 T 29-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D CDC59_RS07405 395a9cb10fb2a1d383f2579f34a7ee59 401 Gene3D G3DSA:3.40.50.720 18 211 6.4E-4 T 29-03-2018 CDC59_RS07405 395a9cb10fb2a1d383f2579f34a7ee59 401 PIRSF PIRSF015557 2 401 1.1E-165 T 29-03-2018 IPR016633 Uncharacterised conserved protein UCP015557 CDC59_RS07405 395a9cb10fb2a1d383f2579f34a7ee59 401 TIGRFAM TIGR03837 efp_adjacent_2: conserved hypothetical protein, PP_1857 family 7 397 8.3E-155 T 29-03-2018 IPR016633 Uncharacterised conserved protein UCP015557 CDC59_RS07405 395a9cb10fb2a1d383f2579f34a7ee59 401 Pfam PF10093 Uncharacterized protein conserved in bacteria (DUF2331) 7 397 8.8E-153 T 29-03-2018 IPR016633 Uncharacterised conserved protein UCP015557 CDC59_RS09285 7b75eb7cfee71f70f2cab7b5d218a8cb 310 SUPERFAMILY SSF103481 215 301 4.45E-6 T 29-03-2018 CDC59_RS09285 7b75eb7cfee71f70f2cab7b5d218a8cb 310 Pfam PF00892 EamA-like transporter family 3 137 1.2E-9 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CDC59_RS02045 2d7e87495a5a7f15e3b35a9b8ddcce85 296 Gene3D G3DSA:1.10.3720.10 8 287 3.8E-41 T 29-03-2018 CDC59_RS02045 2d7e87495a5a7f15e3b35a9b8ddcce85 296 SUPERFAMILY SSF161098 51 275 2.75E-47 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS02045 2d7e87495a5a7f15e3b35a9b8ddcce85 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 82 282 1.2E-17 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS04920 d5b27507d491a72d8e0cb212f391007e 540 SUPERFAMILY SSF51905 211 327 8.91E-56 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS04920 d5b27507d491a72d8e0cb212f391007e 540 SUPERFAMILY SSF51905 480 539 8.91E-56 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS04920 d5b27507d491a72d8e0cb212f391007e 540 SUPERFAMILY SSF51905 8 178 8.91E-56 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS04920 d5b27507d491a72d8e0cb212f391007e 540 Gene3D G3DSA:3.50.50.60 3 540 3.0E-62 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS04920 d5b27507d491a72d8e0cb212f391007e 540 Pfam PF05199 GMC oxidoreductase 417 532 1.1E-19 T 29-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 CDC59_RS04920 d5b27507d491a72d8e0cb212f391007e 540 Pfam PF00732 GMC oxidoreductase 237 322 1.4E-4 T 29-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CDC59_RS04920 d5b27507d491a72d8e0cb212f391007e 540 Pfam PF01266 FAD dependent oxidoreductase 11 43 1.5E-6 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CDC59_RS04920 d5b27507d491a72d8e0cb212f391007e 540 SUPERFAMILY SSF54373 400 473 1.8E-5 T 29-03-2018 CDC59_RS07050 69b84de6d29287800c70b79d5c5ba0a2 115 Gene3D G3DSA:1.10.760.10 6 105 1.6E-17 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS07050 69b84de6d29287800c70b79d5c5ba0a2 115 SUPERFAMILY SSF46626 1 105 7.86E-21 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS14480 ba8ce8673a51a51abe249755f0a79c40 240 Gene3D G3DSA:3.40.50.2020 64 240 6.4E-27 T 29-03-2018 CDC59_RS14480 ba8ce8673a51a51abe249755f0a79c40 240 Pfam PF00156 Phosphoribosyl transferase domain 148 237 3.8E-7 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CDC59_RS14480 ba8ce8673a51a51abe249755f0a79c40 240 SUPERFAMILY SSF53271 62 238 1.19E-38 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CDC59_RS03175 02b080d6c424718e1a4db7bc3c50610b 320 SUPERFAMILY SSF51261 154 289 1.46E-56 T 29-03-2018 IPR011055 Duplicated hybrid motif CDC59_RS03175 02b080d6c424718e1a4db7bc3c50610b 320 Gene3D G3DSA:2.70.70.10 133 294 3.4E-43 T 29-03-2018 CDC59_RS03175 02b080d6c424718e1a4db7bc3c50610b 320 Pfam PF01551 Peptidase family M23 191 285 1.3E-31 T 29-03-2018 IPR016047 Peptidase M23 CDC59_RS05400 9c4d883eafbbdf36d8051b325a326434 284 Gene3D G3DSA:3.40.190.10 173 254 1.1E-23 T 29-03-2018 CDC59_RS05400 9c4d883eafbbdf36d8051b325a326434 284 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 1 57 1.1E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS05400 9c4d883eafbbdf36d8051b325a326434 284 SUPERFAMILY SSF53850 83 283 5.97E-42 T 29-03-2018 CDC59_RS05400 9c4d883eafbbdf36d8051b325a326434 284 Gene3D G3DSA:3.40.190.10 86 172 4.5E-16 T 29-03-2018 CDC59_RS05400 9c4d883eafbbdf36d8051b325a326434 284 Gene3D G3DSA:1.10.10.10 1 78 3.0E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS05400 9c4d883eafbbdf36d8051b325a326434 284 SUPERFAMILY SSF46785 2 106 2.18E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS05400 9c4d883eafbbdf36d8051b325a326434 284 Pfam PF03466 LysR substrate binding domain 83 282 3.8E-40 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS14115 3efbedbec4df90e1d96fa627d3ab14d9 287 Gene3D G3DSA:3.20.20.370 70 280 1.5E-42 T 29-03-2018 CDC59_RS14115 3efbedbec4df90e1d96fa627d3ab14d9 287 Pfam PF01522 Polysaccharide deacetylase 79 198 3.5E-26 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CDC59_RS14115 3efbedbec4df90e1d96fa627d3ab14d9 287 SUPERFAMILY SSF88713 51 271 1.38E-52 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CDC59_RS17020 b36e445930185502c75c20cb34cefa32 401 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 1 383 6.9E-95 T 29-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G CDC59_RS17020 b36e445930185502c75c20cb34cefa32 401 Gene3D G3DSA:2.60.98.20 153 283 4.8E-24 T 29-03-2018 IPR011491 Flagellar hook protein FlgE CDC59_RS17020 b36e445930185502c75c20cb34cefa32 401 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 323 400 2.0E-19 T 29-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CDC59_RS17020 b36e445930185502c75c20cb34cefa32 401 Pfam PF07559 Flagellar basal body protein FlaE 179 282 6.5E-18 T 29-03-2018 IPR011491 Flagellar hook protein FlgE CDC59_RS17020 b36e445930185502c75c20cb34cefa32 401 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 9 29 - T 29-03-2018 IPR019776 Flagellar basal body rod protein, conserved site CDC59_RS17020 b36e445930185502c75c20cb34cefa32 401 Pfam PF00460 Flagella basal body rod protein 3 33 9.3E-12 T 29-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CDC59_RS17020 b36e445930185502c75c20cb34cefa32 401 SUPERFAMILY SSF117143 79 362 1.44E-72 T 29-03-2018 CDC59_RS21050 0f10249fdd9db10fa2c1864c69955484 130 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 28 104 2.8E-24 T 29-03-2018 CDC59_RS21050 0f10249fdd9db10fa2c1864c69955484 130 Gene3D G3DSA:3.10.20.30 23 114 3.6E-6 T 29-03-2018 IPR012675 Beta-grasp domain CDC59_RS21050 0f10249fdd9db10fa2c1864c69955484 130 SUPERFAMILY SSF54292 29 115 1.17E-18 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CDC59_RS04960 a4f3ab010691912ba54a58cf8823bee1 568 Gene3D G3DSA:3.40.50.980 20 215 6.9E-45 T 29-03-2018 CDC59_RS04960 a4f3ab010691912ba54a58cf8823bee1 568 Gene3D G3DSA:3.30.300.30 456 568 8.3E-24 T 29-03-2018 CDC59_RS04960 a4f3ab010691912ba54a58cf8823bee1 568 Gene3D G3DSA:3.40.50.980 216 365 1.6E-41 T 29-03-2018 CDC59_RS04960 a4f3ab010691912ba54a58cf8823bee1 568 Pfam PF13193 AMP-binding enzyme C-terminal domain 468 545 4.8E-19 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CDC59_RS04960 a4f3ab010691912ba54a58cf8823bee1 568 Gene3D G3DSA:2.30.38.10 366 452 1.4E-27 T 29-03-2018 CDC59_RS04960 a4f3ab010691912ba54a58cf8823bee1 568 SUPERFAMILY SSF56801 14 556 1.7E-152 T 29-03-2018 CDC59_RS04960 a4f3ab010691912ba54a58cf8823bee1 568 Pfam PF00501 AMP-binding enzyme 29 458 3.3E-106 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CDC59_RS04960 a4f3ab010691912ba54a58cf8823bee1 568 ProSitePatterns PS00455 Putative AMP-binding domain signature. 210 221 - T 29-03-2018 IPR020845 AMP-binding, conserved site CDC59_RS14155 12d7a7cc1dea399f561c48f60aaa5a7c 178 Hamap MF_00984 Single-stranded DNA-binding protein. 4 111 37.969 T 29-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CDC59_RS14155 12d7a7cc1dea399f561c48f60aaa5a7c 178 Pfam PF00436 Single-strand binding protein family 4 107 1.1E-40 T 29-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 CDC59_RS14155 12d7a7cc1dea399f561c48f60aaa5a7c 178 Gene3D G3DSA:2.40.50.140 1 119 9.5E-44 T 29-03-2018 CDC59_RS14155 12d7a7cc1dea399f561c48f60aaa5a7c 178 SUPERFAMILY SSF50249 3 178 1.06E-60 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDC59_RS14155 12d7a7cc1dea399f561c48f60aaa5a7c 178 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 2 178 6.7E-53 T 29-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CDC59_RS13990 8ecb3808c3eb1750db51836f93273022 193 ProDom PD085709 MEMBRANE RP436 UNCHARACTERIZED INTEGRAL PREDICTED TRANSMEMBRANE 62 150 0.006 T 29-03-2018 IPR020143 Uncharacterised protein family, RP436 CDC59_RS10910 adac7800b66ab5ea78f918e3ebf910b3 263 SUPERFAMILY SSF52540 15 247 1.06E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS10910 adac7800b66ab5ea78f918e3ebf910b3 263 Pfam PF00005 ABC transporter 32 187 6.2E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS10910 adac7800b66ab5ea78f918e3ebf910b3 263 Gene3D G3DSA:3.40.50.300 13 260 1.5E-61 T 29-03-2018 CDC59_RS10910 adac7800b66ab5ea78f918e3ebf910b3 263 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS10910 adac7800b66ab5ea78f918e3ebf910b3 263 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 17 263 4.7E-121 T 29-03-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 CDC59_RS10910 adac7800b66ab5ea78f918e3ebf910b3 263 SMART SM00382 41 251 1.5E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS02245 fc723a4bd6b8499ae26e2708a3b16eae 104 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 12 102 21.604 T 29-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 CDC59_RS02245 fc723a4bd6b8499ae26e2708a3b16eae 104 Pfam PF00276 Ribosomal protein L23 13 99 1.7E-30 T 29-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 CDC59_RS02245 fc723a4bd6b8499ae26e2708a3b16eae 104 Gene3D G3DSA:3.30.70.330 10 104 3.8E-29 T 29-03-2018 CDC59_RS02245 fc723a4bd6b8499ae26e2708a3b16eae 104 SUPERFAMILY SSF54189 8 97 2.12E-29 T 29-03-2018 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS10040 714d08f65dd9d34331501b812bd723d9 264 Gene3D G3DSA:3.40.50.300 1 253 2.3E-48 T 29-03-2018 CDC59_RS10040 714d08f65dd9d34331501b812bd723d9 264 Pfam PF00005 ABC transporter 22 177 2.4E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS10040 714d08f65dd9d34331501b812bd723d9 264 SMART SM00382 31 226 3.1E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS10040 714d08f65dd9d34331501b812bd723d9 264 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS10040 714d08f65dd9d34331501b812bd723d9 264 SUPERFAMILY SSF52540 2 230 6.92E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS15965 8602b69c5a4322038550369afb75722f 67 PRINTS PR00050 Cold shock protein signature 25 34 1.5E-16 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CDC59_RS15965 8602b69c5a4322038550369afb75722f 67 PRINTS PR00050 Cold shock protein signature 40 58 1.5E-16 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CDC59_RS15965 8602b69c5a4322038550369afb75722f 67 PRINTS PR00050 Cold shock protein signature 4 19 1.5E-16 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CDC59_RS15965 8602b69c5a4322038550369afb75722f 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 64 9.9E-29 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CDC59_RS15965 8602b69c5a4322038550369afb75722f 67 Gene3D G3DSA:2.40.50.140 1 66 2.1E-27 T 29-03-2018 CDC59_RS15965 8602b69c5a4322038550369afb75722f 67 PIRSF PIRSF002599 1 67 3.1E-23 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 CDC59_RS15965 8602b69c5a4322038550369afb75722f 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 29-03-2018 IPR019844 Cold-shock conserved site CDC59_RS15965 8602b69c5a4322038550369afb75722f 67 SUPERFAMILY SSF50249 1 65 1.05E-24 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDC59_RS15965 8602b69c5a4322038550369afb75722f 67 SMART SM00357 3 67 2.6E-29 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 CDC59_RS12850 e67b97ca528dc2df9ab640a56d67110e 402 Pfam PF11871 Domain of unknown function (DUF3391) 3 129 1.3E-35 T 29-03-2018 IPR021812 Protein of unknown function DUF3391 CDC59_RS12850 e67b97ca528dc2df9ab640a56d67110e 402 SMART SM00471 156 292 6.1E-10 T 29-03-2018 IPR003607 HD/PDEase domain CDC59_RS12850 e67b97ca528dc2df9ab640a56d67110e 402 Pfam PF13487 HD domain 211 273 2.2E-15 T 29-03-2018 CDC59_RS12850 e67b97ca528dc2df9ab640a56d67110e 402 Gene3D G3DSA:1.10.3210.10 68 324 1.4E-45 T 29-03-2018 CDC59_RS12850 e67b97ca528dc2df9ab640a56d67110e 402 SUPERFAMILY SSF109604 153 321 3.53E-36 T 29-03-2018 CDC59_RS12530 25183fc4aab50d6d6e8fbc5d2238d399 238 Gene3D G3DSA:3.40.50.300 1 238 5.3E-56 T 29-03-2018 CDC59_RS12530 25183fc4aab50d6d6e8fbc5d2238d399 238 SUPERFAMILY SSF52540 4 236 2.0E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS12530 25183fc4aab50d6d6e8fbc5d2238d399 238 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS12530 25183fc4aab50d6d6e8fbc5d2238d399 238 SMART SM00382 30 217 1.3E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS12530 25183fc4aab50d6d6e8fbc5d2238d399 238 PIRSF PIRSF039137 1 238 1.3E-107 T 29-03-2018 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 CDC59_RS12530 25183fc4aab50d6d6e8fbc5d2238d399 238 Pfam PF00005 ABC transporter 22 166 5.7E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS02505 459300175f8af01751532ea738da1c3d 1582 Pfam PF04898 Glutamate synthase central domain 491 775 2.0E-113 T 29-03-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 CDC59_RS02505 459300175f8af01751532ea738da1c3d 1582 Pfam PF01493 GXGXG motif 1314 1499 1.4E-82 T 29-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CDC59_RS02505 459300175f8af01751532ea738da1c3d 1582 SUPERFAMILY SSF51395 484 945 2.36E-268 T 29-03-2018 CDC59_RS02505 459300175f8af01751532ea738da1c3d 1582 SUPERFAMILY SSF51395 973 1268 2.36E-268 T 29-03-2018 CDC59_RS02505 459300175f8af01751532ea738da1c3d 1582 SUPERFAMILY SSF56235 37 462 5.06E-154 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CDC59_RS02505 459300175f8af01751532ea738da1c3d 1582 SUPERFAMILY SSF69336 1282 1569 1.22E-96 T 29-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CDC59_RS02505 459300175f8af01751532ea738da1c3d 1582 Pfam PF00310 Glutamine amidotransferases class-II 37 460 7.8E-186 T 29-03-2018 IPR017932 Glutamine amidotransferase type 2 domain CDC59_RS02505 459300175f8af01751532ea738da1c3d 1582 Pfam PF01645 Conserved region in glutamate synthase 836 1233 7.4E-158 T 29-03-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 CDC59_RS02505 459300175f8af01751532ea738da1c3d 1582 Gene3D G3DSA:3.60.20.10 37 469 3.4E-163 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CDC59_RS02505 459300175f8af01751532ea738da1c3d 1582 Gene3D G3DSA:3.20.20.70 470 818 2.4E-96 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS02505 459300175f8af01751532ea738da1c3d 1582 Gene3D G3DSA:2.160.20.60 1288 1582 3.8E-121 T 29-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CDC59_RS02505 459300175f8af01751532ea738da1c3d 1582 Gene3D G3DSA:3.20.20.70 819 1285 1.4E-169 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS15600 a4e9aa50c31990c8400c6b8df02ab79d 631 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 140 599 4.5E-214 T 29-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CDC59_RS15600 a4e9aa50c31990c8400c6b8df02ab79d 631 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 140 601 57.072 T 29-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CDC59_RS15600 a4e9aa50c31990c8400c6b8df02ab79d 631 Pfam PF13667 ThiC-associated domain 25 100 1.6E-30 T 29-03-2018 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CDC59_RS15600 a4e9aa50c31990c8400c6b8df02ab79d 631 Pfam PF01964 Radical SAM ThiC family 142 596 3.9E-199 T 29-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CDC59_RS03350 454ea5344ca18a96e5c48cfadde17bcb 158 Gene3D G3DSA:3.30.70.920 65 151 8.5E-22 T 29-03-2018 CDC59_RS03350 454ea5344ca18a96e5c48cfadde17bcb 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 4.9E-7 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CDC59_RS03350 454ea5344ca18a96e5c48cfadde17bcb 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 4.9E-7 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CDC59_RS03350 454ea5344ca18a96e5c48cfadde17bcb 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 4.9E-7 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CDC59_RS03350 454ea5344ca18a96e5c48cfadde17bcb 158 Gene3D G3DSA:1.10.10.10 1 64 2.3E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS03350 454ea5344ca18a96e5c48cfadde17bcb 158 Pfam PF13412 Winged helix-turn-helix DNA-binding 3 48 3.8E-12 T 29-03-2018 CDC59_RS03350 454ea5344ca18a96e5c48cfadde17bcb 158 SMART SM00344 3 112 4.5E-38 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CDC59_RS03350 454ea5344ca18a96e5c48cfadde17bcb 158 Pfam PF01037 Lrp/AsnC ligand binding domain 69 142 1.3E-18 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CDC59_RS03350 454ea5344ca18a96e5c48cfadde17bcb 158 SUPERFAMILY SSF54909 64 152 1.61E-16 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CDC59_RS03350 454ea5344ca18a96e5c48cfadde17bcb 158 SUPERFAMILY SSF46785 3 88 1.01E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS20865 9335385b33946ee75e7df8152e67963e 403 Gene3D G3DSA:3.10.490.10 110 372 2.1E-14 T 29-03-2018 CDC59_RS20865 9335385b33946ee75e7df8152e67963e 403 Pfam PF04752 ChaC-like protein 155 223 2.0E-7 T 29-03-2018 IPR006840 Glutathione-specific gamma-glutamylcyclotransferase GO:0003839|GO:0006751 Reactome: R-HSA-174403 CDC59_RS04395 6f2d2fc56bace331b90cb618c29722b8 155 Gene3D G3DSA:3.40.50.2300 23 155 1.9E-31 T 29-03-2018 CDC59_RS04395 6f2d2fc56bace331b90cb618c29722b8 155 SMART SM00448 30 143 3.8E-33 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS04395 6f2d2fc56bace331b90cb618c29722b8 155 SUPERFAMILY SSF52172 24 148 7.54E-35 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS04395 6f2d2fc56bace331b90cb618c29722b8 155 Pfam PF00072 Response regulator receiver domain 32 144 1.1E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS07470 b8c138307011bdabc620b900ef1678eb 432 Gene3D G3DSA:1.20.1250.20 213 428 4.0E-27 T 29-03-2018 CDC59_RS07470 b8c138307011bdabc620b900ef1678eb 432 Gene3D G3DSA:1.20.1250.20 1 202 1.8E-40 T 29-03-2018 CDC59_RS07470 b8c138307011bdabc620b900ef1678eb 432 Pfam PF07690 Major Facilitator Superfamily 15 373 4.6E-54 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDC59_RS07470 b8c138307011bdabc620b900ef1678eb 432 SUPERFAMILY SSF103473 4 414 3.66E-78 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS07470 b8c138307011bdabc620b900ef1678eb 432 PIRSF PIRSF002808 1 428 1.3E-38 T 29-03-2018 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 CDC59_RS18165 7b77cc0b045a58deab577b39978814b2 431 Pfam PF13795 HupE / UreJ protein 197 358 1.6E-43 T 29-03-2018 IPR032809 Putative HupE/UreJ protein CDC59_RS07500 f733d8f9a6403565ba85c88cf751b08b 232 Gene3D G3DSA:3.90.850.10 2 232 1.3E-78 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CDC59_RS07500 f733d8f9a6403565ba85c88cf751b08b 232 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 27 231 1.0E-57 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CDC59_RS07500 f733d8f9a6403565ba85c88cf751b08b 232 SUPERFAMILY SSF56529 22 231 3.92E-72 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CDC59_RS07270 0aa8f90236935e101f0b83a985c93efb 378 SUPERFAMILY SSF52096 263 324 2.22E-42 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CDC59_RS07270 0aa8f90236935e101f0b83a985c93efb 378 SUPERFAMILY SSF52096 107 234 2.22E-42 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CDC59_RS07270 0aa8f90236935e101f0b83a985c93efb 378 Pfam PF01343 Peptidase family S49 186 329 1.0E-38 T 29-03-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 CDC59_RS07270 0aa8f90236935e101f0b83a985c93efb 378 Gene3D G3DSA:3.90.226.10 107 353 3.3E-35 T 29-03-2018 CDC59_RS00570 8f501cbc5b1e5fa2207c7df14dae9ec3 95 ProSitePatterns PS00151 Acylphosphatase signature 2. 35 51 - T 29-03-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CDC59_RS00570 8f501cbc5b1e5fa2207c7df14dae9ec3 95 PRINTS PR00112 Acylphosphatase signature 27 52 3.0E-6 T 29-03-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CDC59_RS00570 8f501cbc5b1e5fa2207c7df14dae9ec3 95 PRINTS PR00112 Acylphosphatase signature 6 21 3.0E-6 T 29-03-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CDC59_RS00570 8f501cbc5b1e5fa2207c7df14dae9ec3 95 Pfam PF00708 Acylphosphatase 9 90 4.3E-21 T 29-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CDC59_RS00570 8f501cbc5b1e5fa2207c7df14dae9ec3 95 Gene3D G3DSA:3.30.70.100 1 95 1.9E-21 T 29-03-2018 CDC59_RS00570 8f501cbc5b1e5fa2207c7df14dae9ec3 95 SUPERFAMILY SSF54975 3 92 2.09E-23 T 29-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CDC59_RS17085 0f4003119269bc16b6896aa4dd6f8f3b 262 Pfam PF01311 Bacterial export proteins, family 1 14 245 6.8E-59 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CDC59_RS17085 0f4003119269bc16b6896aa4dd6f8f3b 262 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 203 222 2.1E-21 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CDC59_RS17085 0f4003119269bc16b6896aa4dd6f8f3b 262 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 181 203 2.1E-21 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CDC59_RS17085 0f4003119269bc16b6896aa4dd6f8f3b 262 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 81 100 2.1E-21 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CDC59_RS17085 0f4003119269bc16b6896aa4dd6f8f3b 262 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 22 43 2.1E-21 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CDC59_RS17085 0f4003119269bc16b6896aa4dd6f8f3b 262 TIGRFAM TIGR01400 fliR: flagellar biosynthetic protein FliR 15 250 1.1E-54 T 29-03-2018 IPR006303 Flagellar biosynthesis protein FliR GO:0016021|GO:0044780 CDC59_RS19415 ae2cb43fb51a8cefce1dd6f2e3d0e503 426 Pfam PF09298 Fumarylacetoacetase N-terminal 22 123 9.9E-30 T 29-03-2018 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 CDC59_RS19415 ae2cb43fb51a8cefce1dd6f2e3d0e503 426 Gene3D G3DSA:3.90.850.10 121 408 6.5E-88 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CDC59_RS19415 ae2cb43fb51a8cefce1dd6f2e3d0e503 426 SUPERFAMILY SSF56529 125 422 3.4E-101 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CDC59_RS19415 ae2cb43fb51a8cefce1dd6f2e3d0e503 426 SUPERFAMILY SSF63433 7 123 5.36E-35 T 29-03-2018 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 CDC59_RS19415 ae2cb43fb51a8cefce1dd6f2e3d0e503 426 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 129 419 9.2E-60 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CDC59_RS19415 ae2cb43fb51a8cefce1dd6f2e3d0e503 426 TIGRFAM TIGR01266 fum_ac_acetase: fumarylacetoacetase 7 422 1.9E-179 T 29-03-2018 IPR005959 Fumarylacetoacetase GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 CDC59_RS19415 ae2cb43fb51a8cefce1dd6f2e3d0e503 426 Gene3D G3DSA:2.30.30.230 7 119 4.6E-33 T 29-03-2018 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 CDC59_RS23480 d2a9fd35ffe5a8548050bb36b39cdac3 769 SMART SM00885 332 476 1.3E-32 T 29-03-2018 IPR014818 Bacteriophage/plasmid primase, P4, C-terminal CDC59_RS23480 d2a9fd35ffe5a8548050bb36b39cdac3 769 Gene3D G3DSA:3.40.50.300 441 659 5.0E-10 T 29-03-2018 CDC59_RS23480 d2a9fd35ffe5a8548050bb36b39cdac3 769 TIGRFAM TIGR01613 primase_Cterm: phage/plasmid primase, P4 family, C-terminal domain 423 729 1.8E-110 T 29-03-2018 IPR006500 DNA primase, phage/plasmid CDC59_RS23480 d2a9fd35ffe5a8548050bb36b39cdac3 769 Gene3D G3DSA:3.40.1360.10 183 302 7.2E-11 T 29-03-2018 CDC59_RS23480 d2a9fd35ffe5a8548050bb36b39cdac3 769 Pfam PF08706 D5 N terminal like 332 474 1.4E-22 T 29-03-2018 IPR014818 Bacteriophage/plasmid primase, P4, C-terminal CDC59_RS22905 ac6e251db3cb4ba289a0b98ff04e7242 411 Gene3D G3DSA:3.90.1150.10 276 410 9.0E-40 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS22905 ac6e251db3cb4ba289a0b98ff04e7242 411 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 6 405 1.1E-103 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CDC59_RS22905 ac6e251db3cb4ba289a0b98ff04e7242 411 Gene3D G3DSA:3.40.640.10 1 270 1.4E-39 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDC59_RS22905 ac6e251db3cb4ba289a0b98ff04e7242 411 SUPERFAMILY SSF53383 26 406 2.53E-86 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS22905 ac6e251db3cb4ba289a0b98ff04e7242 411 PIRSF PIRSF001434 1 409 8.4E-123 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CDC59_RS18085 7b64151a555e82556df4c6138f116423 589 Gene3D G3DSA:3.10.20.310 90 162 1.2E-14 T 29-03-2018 CDC59_RS18085 7b64151a555e82556df4c6138f116423 589 Pfam PF03865 Haemolysin secretion/activation protein ShlB/FhaC/HecB 240 549 8.3E-74 T 29-03-2018 IPR005565 Haemolysin activator HlyB, C-terminal CDC59_RS18085 7b64151a555e82556df4c6138f116423 589 Pfam PF08479 POTRA domain, ShlB-type 87 162 4.1E-23 T 29-03-2018 IPR013686 Polypeptide-transport-associated, ShlB-type CDC59_RS18085 7b64151a555e82556df4c6138f116423 589 PIRSF PIRSF029745 1 589 7.9E-133 T 29-03-2018 IPR027282 Two partner secretion pathway transporter GO:0015031 CDC59_RS18085 7b64151a555e82556df4c6138f116423 589 Pfam PF17287 POTRA domain 163 235 2.4E-15 T 29-03-2018 IPR035251 ShlB, POTRA domain CDC59_RS18085 7b64151a555e82556df4c6138f116423 589 Gene3D G3DSA:2.40.160.50 208 577 2.8E-38 T 29-03-2018 CDC59_RS07895 efaab7d0aac297eafc1542365037a7ee 322 SUPERFAMILY SSF52096 5 316 2.72E-100 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CDC59_RS07895 efaab7d0aac297eafc1542365037a7ee 322 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 113 131 1.8E-45 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CDC59_RS07895 efaab7d0aac297eafc1542365037a7ee 322 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 134 150 1.8E-45 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CDC59_RS07895 efaab7d0aac297eafc1542365037a7ee 322 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 88 99 1.8E-45 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CDC59_RS07895 efaab7d0aac297eafc1542365037a7ee 322 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 197 206 1.8E-45 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CDC59_RS07895 efaab7d0aac297eafc1542365037a7ee 322 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 153 166 1.8E-45 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CDC59_RS07895 efaab7d0aac297eafc1542365037a7ee 322 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 169 182 1.8E-45 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CDC59_RS07895 efaab7d0aac297eafc1542365037a7ee 322 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 6 148 4.2E-65 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CDC59_RS07895 efaab7d0aac297eafc1542365037a7ee 322 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 2 319 7.5E-148 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CDC59_RS07895 efaab7d0aac297eafc1542365037a7ee 322 Gene3D G3DSA:3.90.226.10 12 317 8.1E-66 T 29-03-2018 CDC59_RS07895 efaab7d0aac297eafc1542365037a7ee 322 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 5 316 49.441 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CDC59_RS07755 bf2e5be0c1f2500b12ef2b577e97665f 225 Pfam PF02163 Peptidase family M50 137 190 4.2E-8 T 29-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 CDC59_RS20020 f2b02526f93c0bf7dc41dc392f163ee7 469 SUPERFAMILY SSF51604 162 438 4.04E-78 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CDC59_RS20020 f2b02526f93c0bf7dc41dc392f163ee7 469 Gene3D G3DSA:3.20.20.120 164 437 4.9E-51 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CDC59_RS20020 f2b02526f93c0bf7dc41dc392f163ee7 469 Gene3D G3DSA:3.30.390.10 6 163 9.0E-33 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CDC59_RS20020 f2b02526f93c0bf7dc41dc392f163ee7 469 Pfam PF13378 Enolase C-terminal domain-like 211 428 2.2E-35 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CDC59_RS20020 f2b02526f93c0bf7dc41dc392f163ee7 469 SMART SM00922 208 308 5.2E-14 T 29-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CDC59_RS20020 f2b02526f93c0bf7dc41dc392f163ee7 469 SUPERFAMILY SSF54826 14 160 8.49E-26 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CDC59_RS03890 9963f37c97b6ee34b1f0f883a330fdce 196 TIGRFAM TIGR02523 type_IV_pilV: type IV pilus modification protein PilV 17 160 1.9E-16 T 29-03-2018 IPR013362 Pilus modification type IV, PilV CDC59_RS03890 9963f37c97b6ee34b1f0f883a330fdce 196 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 18 38 - T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS03890 9963f37c97b6ee34b1f0f883a330fdce 196 Gene3D G3DSA:3.30.700.10 21 191 6.1E-4 T 29-03-2018 CDC59_RS03890 9963f37c97b6ee34b1f0f883a330fdce 196 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 17 39 6.9E-5 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS03890 9963f37c97b6ee34b1f0f883a330fdce 196 Pfam PF07963 Prokaryotic N-terminal methylation motif 15 39 4.6E-6 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS10470 7f935cb25691dff11ece1e9a9cec7e36 194 Pfam PF09361 Phasin protein 5 104 1.2E-30 T 29-03-2018 IPR018968 Phasin CDC59_RS10470 7f935cb25691dff11ece1e9a9cec7e36 194 TIGRFAM TIGR01841 phasin: phasin family protein 25 112 2.1E-30 T 29-03-2018 IPR010127 Phasin, subfamily 1 CDC59_RS12635 5e7d9864d9c5fc32f8c3ff28370eaabb 332 SMART SM00904 182 307 1.0E-55 T 29-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CDC59_RS12635 5e7d9864d9c5fc32f8c3ff28370eaabb 332 Pfam PF01687 Riboflavin kinase 183 306 1.8E-35 T 29-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CDC59_RS12635 5e7d9864d9c5fc32f8c3ff28370eaabb 332 PIRSF PIRSF004491 2 309 8.7E-98 T 29-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CDC59_RS12635 5e7d9864d9c5fc32f8c3ff28370eaabb 332 Pfam PF06574 FAD synthetase 11 165 5.9E-56 T 29-03-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CDC59_RS12635 5e7d9864d9c5fc32f8c3ff28370eaabb 332 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 17 75 8.3E-8 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CDC59_RS12635 5e7d9864d9c5fc32f8c3ff28370eaabb 332 SUPERFAMILY SSF52374 15 177 1.15E-37 T 29-03-2018 CDC59_RS12635 5e7d9864d9c5fc32f8c3ff28370eaabb 332 SUPERFAMILY SSF82114 173 307 7.85E-42 T 29-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CDC59_RS12635 5e7d9864d9c5fc32f8c3ff28370eaabb 332 Gene3D G3DSA:2.40.30.30 179 317 7.0E-39 T 29-03-2018 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 CDC59_RS12635 5e7d9864d9c5fc32f8c3ff28370eaabb 332 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 17 306 4.1E-91 T 29-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CDC59_RS12635 5e7d9864d9c5fc32f8c3ff28370eaabb 332 Gene3D G3DSA:3.40.50.620 1 178 2.5E-51 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDC59_RS04125 ec4bf757e22fadec191bf7347abc0eed 235 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 44 226 1.1E-9 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS04125 ec4bf757e22fadec191bf7347abc0eed 235 Gene3D G3DSA:1.10.3720.10 2 233 1.7E-26 T 29-03-2018 CDC59_RS04125 ec4bf757e22fadec191bf7347abc0eed 235 SUPERFAMILY SSF161098 9 225 7.72E-37 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS15580 cb907a6608eff8fc7420593e3a6b3ab7 177 Gene3D G3DSA:4.10.1070.10 55 165 2.2E-6 T 29-03-2018 CDC59_RS15580 cb907a6608eff8fc7420593e3a6b3ab7 177 Gene3D G3DSA:3.90.1340.10 1 54 3.4E-23 T 29-03-2018 IPR011083 Phage tail collar domain CDC59_RS15580 cb907a6608eff8fc7420593e3a6b3ab7 177 SUPERFAMILY SSF88874 1 171 1.27E-49 T 29-03-2018 CDC59_RS15580 cb907a6608eff8fc7420593e3a6b3ab7 177 Pfam PF07484 Phage Tail Collar Domain 6 62 2.3E-27 T 29-03-2018 IPR011083 Phage tail collar domain CDC59_RS19160 4966e695ec19b1b36ece9868ba681ef9 375 Pfam PF01757 Acyltransferase family 9 334 3.5E-27 T 29-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CDC59_RS05920 8547a2fd9b54965d74eecae12c322b19 425 Gene3D G3DSA:3.30.9.10 223 369 1.5E-20 T 29-03-2018 CDC59_RS05920 8547a2fd9b54965d74eecae12c322b19 425 Pfam PF01266 FAD dependent oxidoreductase 3 408 1.4E-62 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CDC59_RS05920 8547a2fd9b54965d74eecae12c322b19 425 Hamap MF_01202 D-amino acid dehydrogenase [dadA]. 1 421 53.817 T 29-03-2018 IPR023080 D-amino acid dehydrogenase DadA GO:0008718|GO:0019478|GO:0055114 CDC59_RS05920 8547a2fd9b54965d74eecae12c322b19 425 Gene3D G3DSA:3.30.9.10 148 222 7.7E-8 T 29-03-2018 CDC59_RS05920 8547a2fd9b54965d74eecae12c322b19 425 SUPERFAMILY SSF54373 272 370 9.16E-11 T 29-03-2018 CDC59_RS05920 8547a2fd9b54965d74eecae12c322b19 425 Gene3D G3DSA:3.40.50.720 2 147 5.7E-11 T 29-03-2018 CDC59_RS05920 8547a2fd9b54965d74eecae12c322b19 425 SUPERFAMILY SSF51905 107 272 2.46E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS05920 8547a2fd9b54965d74eecae12c322b19 425 SUPERFAMILY SSF51905 1 54 2.46E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS05920 8547a2fd9b54965d74eecae12c322b19 425 SUPERFAMILY SSF51905 370 425 2.46E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS20100 9c9f7273b0f74ff1b96791b63d6eef33 288 Gene3D G3DSA:3.40.50.720 4 73 1.9E-6 T 29-03-2018 CDC59_RS20100 9c9f7273b0f74ff1b96791b63d6eef33 288 Gene3D G3DSA:3.40.50.720 78 286 2.7E-10 T 29-03-2018 CDC59_RS20100 9c9f7273b0f74ff1b96791b63d6eef33 288 SUPERFAMILY SSF51735 5 270 6.22E-41 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS20100 9c9f7273b0f74ff1b96791b63d6eef33 288 Pfam PF13460 NAD(P)H-binding 7 181 1.9E-18 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS19540 14ccae4893afb1583dac7a55ca84fcf3 441 Gene3D G3DSA:3.40.50.1820 143 391 6.1E-18 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS19540 14ccae4893afb1583dac7a55ca84fcf3 441 SUPERFAMILY SSF53474 111 338 9.2E-18 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS19540 14ccae4893afb1583dac7a55ca84fcf3 441 Pfam PF01764 Lipase (class 3) 170 306 6.4E-8 T 29-03-2018 IPR002921 Fungal lipase-like domain GO:0006629 Reactome: R-HSA-426048 CDC59_RS21180 c00d97d66fccb1f62192eece3b2a4a3f 779 Gene3D G3DSA:3.40.50.740 318 616 6.4E-50 T 29-03-2018 CDC59_RS21180 c00d97d66fccb1f62192eece3b2a4a3f 779 PIRSF PIRSF000144 1 767 0.0 T 29-03-2018 CDC59_RS21180 c00d97d66fccb1f62192eece3b2a4a3f 779 Gene3D G3DSA:3.40.50.740 110 259 8.3E-41 T 29-03-2018 CDC59_RS21180 c00d97d66fccb1f62192eece3b2a4a3f 779 SUPERFAMILY SSF53706 47 630 3.8E-155 T 29-03-2018 CDC59_RS21180 c00d97d66fccb1f62192eece3b2a4a3f 779 Pfam PF01568 Molydopterin dinucleotide binding domain 649 756 5.4E-8 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CDC59_RS21180 c00d97d66fccb1f62192eece3b2a4a3f 779 Pfam PF00384 Molybdopterin oxidoreductase 109 544 3.0E-28 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS21180 c00d97d66fccb1f62192eece3b2a4a3f 779 SUPERFAMILY SSF50692 645 765 8.59E-14 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain CDC59_RS21180 c00d97d66fccb1f62192eece3b2a4a3f 779 TIGRFAM TIGR01701 Fdhalpha-like: oxidoreductase alpha (molybdopterin) subunit 13 762 1.2E-299 T 29-03-2018 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 CDC59_RS21180 c00d97d66fccb1f62192eece3b2a4a3f 779 Gene3D G3DSA:2.40.40.20 636 773 7.6E-20 T 29-03-2018 CDC59_RS22580 4c7ee9a389db31d0b4224b08cd5607bf 347 SUPERFAMILY SSF56601 68 312 5.63E-12 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CDC59_RS22580 4c7ee9a389db31d0b4224b08cd5607bf 347 Gene3D G3DSA:3.40.710.10 171 325 8.2E-6 T 29-03-2018 CDC59_RS12580 615e4d1aa7dd87876de2cdd323f2e982 533 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 2 511 1.6E-202 T 29-03-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 CDC59_RS12580 615e4d1aa7dd87876de2cdd323f2e982 533 Gene3D G3DSA:3.50.50.60 1 429 6.0E-73 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS12580 615e4d1aa7dd87876de2cdd323f2e982 533 Pfam PF02910 Fumarate reductase flavoprotein C-term 432 512 1.6E-14 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CDC59_RS12580 615e4d1aa7dd87876de2cdd323f2e982 533 Pfam PF00890 FAD binding domain 4 383 3.3E-104 T 29-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CDC59_RS12580 615e4d1aa7dd87876de2cdd323f2e982 533 Gene3D G3DSA:1.20.58.100 430 530 4.0E-27 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CDC59_RS12580 615e4d1aa7dd87876de2cdd323f2e982 533 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 7.9E-8 T 29-03-2018 CDC59_RS12580 615e4d1aa7dd87876de2cdd323f2e982 533 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 346 368 7.9E-8 T 29-03-2018 CDC59_RS12580 615e4d1aa7dd87876de2cdd323f2e982 533 SUPERFAMILY SSF56425 229 344 1.64E-42 T 29-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CDC59_RS12580 615e4d1aa7dd87876de2cdd323f2e982 533 SUPERFAMILY SSF46977 416 517 7.98E-31 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CDC59_RS12580 615e4d1aa7dd87876de2cdd323f2e982 533 SUPERFAMILY SSF51905 2 246 6.48E-74 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS12580 615e4d1aa7dd87876de2cdd323f2e982 533 SUPERFAMILY SSF51905 347 439 6.48E-74 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS17750 8afc5056dd2cfebe83b56ccf2440486d 250 Gene3D G3DSA:3.40.50.150 21 242 1.1E-41 T 29-03-2018 CDC59_RS17750 8afc5056dd2cfebe83b56ccf2440486d 250 SUPERFAMILY SSF53335 7 238 6.04E-45 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS17750 8afc5056dd2cfebe83b56ccf2440486d 250 Pfam PF08241 Methyltransferase domain 46 142 2.1E-23 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CDC59_RS02350 f1da27784e94f6266dc819ebd3cf12dd 121 Gene3D G3DSA:1.10.8.50 1 66 3.7E-23 T 29-03-2018 CDC59_RS02350 f1da27784e94f6266dc819ebd3cf12dd 121 ProSitePatterns PS00646 Ribosomal protein S13 signature. 87 100 - T 29-03-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS02350 f1da27784e94f6266dc819ebd3cf12dd 121 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 119 27.209 T 29-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS02350 f1da27784e94f6266dc819ebd3cf12dd 121 SUPERFAMILY SSF46946 2 114 7.65E-45 T 29-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CDC59_RS02350 f1da27784e94f6266dc819ebd3cf12dd 121 Pfam PF00416 Ribosomal protein S13/S18 3 108 1.5E-30 T 29-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS02350 f1da27784e94f6266dc819ebd3cf12dd 121 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 114 8.5E-53 T 29-03-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS02350 f1da27784e94f6266dc819ebd3cf12dd 121 Gene3D G3DSA:4.10.910.10 86 121 2.9E-25 T 29-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS02350 f1da27784e94f6266dc819ebd3cf12dd 121 PIRSF PIRSF002134 1 121 7.3E-41 T 29-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS02350 f1da27784e94f6266dc819ebd3cf12dd 121 Gene3D G3DSA:4.10.910.10 67 85 1.3E-18 T 29-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CDC59_RS04970 dc1809ff335a445e59b55f811e47342c 246 Pfam PF04752 ChaC-like protein 54 217 1.0E-38 T 29-03-2018 IPR006840 Glutathione-specific gamma-glutamylcyclotransferase GO:0003839|GO:0006751 Reactome: R-HSA-174403 CDC59_RS04970 dc1809ff335a445e59b55f811e47342c 246 Gene3D G3DSA:3.10.490.10 40 226 6.5E-27 T 29-03-2018 CDC59_RS04970 dc1809ff335a445e59b55f811e47342c 246 SUPERFAMILY SSF110857 54 165 8.04E-12 T 29-03-2018 IPR013024 Gamma-glutamyl cyclotransferase-like CDC59_RS08975 58e0c631a6884746311ebdf032367b50 438 Pfam PF07690 Major Facilitator Superfamily 9 358 1.2E-16 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDC59_RS08975 58e0c631a6884746311ebdf032367b50 438 Gene3D G3DSA:1.20.1250.20 219 429 5.7E-7 T 29-03-2018 CDC59_RS08975 58e0c631a6884746311ebdf032367b50 438 SUPERFAMILY SSF103473 5 423 3.27E-23 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS08975 58e0c631a6884746311ebdf032367b50 438 Gene3D G3DSA:1.20.1250.20 1 206 4.2E-15 T 29-03-2018 CDC59_RS12730 6924ada63379193fc046ce58a4cd9309 504 Pfam PF00149 Calcineurin-like phosphoesterase 162 406 5.9E-13 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CDC59_RS12730 6924ada63379193fc046ce58a4cd9309 504 SUPERFAMILY SSF56300 158 488 9.07E-28 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CDC59_RS12730 6924ada63379193fc046ce58a4cd9309 504 Gene3D G3DSA:3.60.21.10 159 491 7.1E-24 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CDC59_RS01590 8574ab6a4471a52d22f29f98e19f8e01 661 Gene3D G3DSA:1.10.287.950 467 661 1.4E-49 T 29-03-2018 CDC59_RS01590 8574ab6a4471a52d22f29f98e19f8e01 661 Gene3D G3DSA:1.10.287.950 357 466 7.1E-17 T 29-03-2018 CDC59_RS01590 8574ab6a4471a52d22f29f98e19f8e01 661 Gene3D G3DSA:3.30.450.20 205 327 1.8E-12 T 29-03-2018 CDC59_RS01590 8574ab6a4471a52d22f29f98e19f8e01 661 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 510 537 3.3E-53 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS01590 8574ab6a4471a52d22f29f98e19f8e01 661 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 433 462 3.3E-53 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS01590 8574ab6a4471a52d22f29f98e19f8e01 661 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 587 616 3.3E-53 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS01590 8574ab6a4471a52d22f29f98e19f8e01 661 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 539 568 3.3E-53 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS01590 8574ab6a4471a52d22f29f98e19f8e01 661 SMART SM00304 359 411 7.0E-12 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CDC59_RS01590 8574ab6a4471a52d22f29f98e19f8e01 661 SUPERFAMILY SSF103190 109 217 1.8E-13 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CDC59_RS01590 8574ab6a4471a52d22f29f98e19f8e01 661 Gene3D G3DSA:3.30.450.20 37 204 1.9E-7 T 29-03-2018 CDC59_RS01590 8574ab6a4471a52d22f29f98e19f8e01 661 SUPERFAMILY SSF58104 379 660 1.57E-72 T 29-03-2018 CDC59_RS01590 8574ab6a4471a52d22f29f98e19f8e01 661 Pfam PF17201 Cache 3/Cache 2 fusion domain 45 335 4.7E-79 T 29-03-2018 IPR033462 Cache 3/Cache 2 fusion domain CDC59_RS01590 8574ab6a4471a52d22f29f98e19f8e01 661 SMART SM00283 412 659 1.2E-92 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CDC59_RS01590 8574ab6a4471a52d22f29f98e19f8e01 661 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 471 627 2.7E-51 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CDC59_RS01590 8574ab6a4471a52d22f29f98e19f8e01 661 Pfam PF00672 HAMP domain 359 406 7.0E-11 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CDC59_RS19615 9ceb635da7f221107e9d7a5756efa15c 262 Pfam PF09850 Type VI secretion system protein DotU 33 230 2.6E-57 T 29-03-2018 IPR017732 Type IV / VI secretion system, DotU CDC59_RS19615 9ceb635da7f221107e9d7a5756efa15c 262 TIGRFAM TIGR03349 IV_VI_DotU: type IV/VI secretion system protein, DotU family 32 237 1.2E-57 T 29-03-2018 IPR017732 Type IV / VI secretion system, DotU CDC59_RS21295 772d204eb631716fd53358829d0da794 465 Pfam PF02378 Phosphotransferase system, EIIC 111 397 1.2E-47 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CDC59_RS21295 772d204eb631716fd53358829d0da794 465 TIGRFAM TIGR01996 PTS-II-BC-sucr: PTS system, sucrose-specific IIBC component 2 449 1.7E-188 T 29-03-2018 IPR010973 Phosphotransferase system, sucrose-specific IIBC component GO:0008982|GO:0009401|GO:0016021 CDC59_RS21295 772d204eb631716fd53358829d0da794 465 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 19 36 - T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CDC59_RS21295 772d204eb631716fd53358829d0da794 465 Pfam PF00367 phosphotransferase system, EIIB 9 41 6.2E-14 T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CDC59_RS21295 772d204eb631716fd53358829d0da794 465 Gene3D G3DSA:3.30.1360.60 4 81 1.5E-22 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CDC59_RS21295 772d204eb631716fd53358829d0da794 465 SUPERFAMILY SSF55604 6 81 7.45E-18 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CDC59_RS12320 fc0a01f94b8def8561683f00ea4a5924 330 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 26 287 1.3E-54 T 29-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 CDC59_RS12320 fc0a01f94b8def8561683f00ea4a5924 330 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 325 100.129 T 29-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 CDC59_RS12320 fc0a01f94b8def8561683f00ea4a5924 330 Pfam PF03186 CobD/Cbib protein 21 304 4.1E-91 T 29-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 CDC59_RS06495 4b3f0fc8d85b63b3be6a3b77cef73e24 160 Pfam PF04972 BON domain 42 101 1.5E-8 T 29-03-2018 IPR007055 BON domain CDC59_RS06495 4b3f0fc8d85b63b3be6a3b77cef73e24 160 Gene3D G3DSA:3.10.350.10 104 160 9.1E-17 T 29-03-2018 CDC59_RS06495 4b3f0fc8d85b63b3be6a3b77cef73e24 160 SMART SM00257 109 158 2.1E-12 T 29-03-2018 IPR018392 LysM domain CDC59_RS06495 4b3f0fc8d85b63b3be6a3b77cef73e24 160 SUPERFAMILY SSF54106 108 158 7.19E-8 T 29-03-2018 IPR018392 LysM domain CDC59_RS06495 4b3f0fc8d85b63b3be6a3b77cef73e24 160 Pfam PF01476 LysM domain 110 158 2.3E-12 T 29-03-2018 IPR018392 LysM domain CDC59_RS06495 4b3f0fc8d85b63b3be6a3b77cef73e24 160 SMART SM00749 40 103 9.7E-4 T 29-03-2018 IPR014004 Transport-associated and nodulation domain, bacteria CDC59_RS20655 8b1cb32cd4ba115b7182f46db20a9882 432 Gene3D G3DSA:1.10.3080.10 2 398 2.1E-61 T 29-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 CDC59_RS20655 8b1cb32cd4ba115b7182f46db20a9882 432 Pfam PF00654 Voltage gated chloride channel 51 381 7.3E-66 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CDC59_RS20655 8b1cb32cd4ba115b7182f46db20a9882 432 SUPERFAMILY SSF81340 3 391 6.41E-84 T 29-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 CDC59_RS17430 1383e843675ac55c79e2f5d95dc9cb7b 373 Pfam PF03824 High-affinity nickel-transport protein 13 363 1.8E-38 T 29-03-2018 IPR011541 Nickel/cobalt transporter, high-affinity GO:0015099|GO:0016021|GO:0035444|GO:0046872 CDC59_RS01550 bd72ce7abacd473e4121aa21213dda17 301 Pfam PF13503 Domain of unknown function (DUF4123) 30 152 1.9E-13 T 29-03-2018 IPR025391 Domain of unknown function DUF4123 CDC59_RS20710 b2ab00b511d8cf78a231fa6520d09fc7 104 Pfam PF02597 ThiS family 5 90 8.3E-18 T 29-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 CDC59_RS20710 b2ab00b511d8cf78a231fa6520d09fc7 104 SUPERFAMILY SSF54285 1 92 5.61E-24 T 29-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CDC59_RS20710 b2ab00b511d8cf78a231fa6520d09fc7 104 Gene3D G3DSA:3.10.20.30 1 90 8.6E-20 T 29-03-2018 IPR012675 Beta-grasp domain CDC59_RS08955 959bd24d22d302469cddf1ecd4960011 89 Pfam PF00887 Acyl CoA binding protein 5 84 1.2E-24 T 29-03-2018 IPR000582 Acyl-CoA-binding protein, ACBP GO:0000062 CDC59_RS08955 959bd24d22d302469cddf1ecd4960011 89 PRINTS PR00689 Acyl-coA-binding protein signature 45 60 2.3E-19 T 29-03-2018 IPR000582 Acyl-CoA-binding protein, ACBP GO:0000062 CDC59_RS08955 959bd24d22d302469cddf1ecd4960011 89 PRINTS PR00689 Acyl-coA-binding protein signature 66 83 2.3E-19 T 29-03-2018 IPR000582 Acyl-CoA-binding protein, ACBP GO:0000062 CDC59_RS08955 959bd24d22d302469cddf1ecd4960011 89 PRINTS PR00689 Acyl-coA-binding protein signature 5 20 2.3E-19 T 29-03-2018 IPR000582 Acyl-CoA-binding protein, ACBP GO:0000062 CDC59_RS08955 959bd24d22d302469cddf1ecd4960011 89 PRINTS PR00689 Acyl-coA-binding protein signature 22 40 2.3E-19 T 29-03-2018 IPR000582 Acyl-CoA-binding protein, ACBP GO:0000062 CDC59_RS08955 959bd24d22d302469cddf1ecd4960011 89 Gene3D G3DSA:1.20.80.10 1 89 1.8E-28 T 29-03-2018 IPR014352 FERM/acyl-CoA-binding protein, 3-helical bundle CDC59_RS08955 959bd24d22d302469cddf1ecd4960011 89 SUPERFAMILY SSF47027 3 85 9.16E-27 T 29-03-2018 IPR000582 Acyl-CoA-binding protein, ACBP GO:0000062 CDC59_RS01695 d5b400f65585eb0925959f3eba4a8027 518 SMART SM00382 260 381 1.0E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS01695 d5b400f65585eb0925959f3eba4a8027 518 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 327 341 - T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CDC59_RS01695 d5b400f65585eb0925959f3eba4a8027 518 Pfam PF00437 Type II/IV secretion system protein 136 399 1.2E-86 T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CDC59_RS01695 d5b400f65585eb0925959f3eba4a8027 518 SUPERFAMILY SSF52540 109 516 7.02E-104 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS01695 d5b400f65585eb0925959f3eba4a8027 518 Gene3D G3DSA:3.40.50.300 233 518 1.2E-65 T 29-03-2018 CDC59_RS01695 d5b400f65585eb0925959f3eba4a8027 518 TIGRFAM TIGR02533 type_II_gspE: type II secretion system protein E 22 516 1.7E-220 T 29-03-2018 IPR013369 Type II secretion system GspE GO:0005524|GO:0008565|GO:0015627|GO:0015628 CDC59_RS01695 d5b400f65585eb0925959f3eba4a8027 518 SUPERFAMILY SSF160246 22 85 7.46E-7 T 29-03-2018 CDC59_RS01695 d5b400f65585eb0925959f3eba4a8027 518 Gene3D G3DSA:3.30.450.90 98 232 3.0E-48 T 29-03-2018 CDC59_RS20990 acd6cd489386bb7fdf9acce0e95df91b 362 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 7 355 7.5E-78 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CDC59_RS20990 acd6cd489386bb7fdf9acce0e95df91b 362 SUPERFAMILY SSF53659 4 358 1.55E-105 T 29-03-2018 CDC59_RS20990 acd6cd489386bb7fdf9acce0e95df91b 362 SMART SM01329 6 355 2.5E-154 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CDC59_RS20990 acd6cd489386bb7fdf9acce0e95df91b 362 Gene3D G3DSA:3.40.718.10 1 212 4.8E-58 T 29-03-2018 CDC59_RS20990 acd6cd489386bb7fdf9acce0e95df91b 362 Gene3D G3DSA:3.40.718.10 213 360 2.4E-50 T 29-03-2018 CDC59_RS20990 acd6cd489386bb7fdf9acce0e95df91b 362 TIGRFAM TIGR02089 TTC: tartrate dehydrogenase 4 358 2.0E-150 T 29-03-2018 IPR011829 Tartrate dehydrogenase GO:0016616|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.93|KEGG: 00650+1.1.1.83 CDC59_RS10445 4a07d99557bc47a6cc97bd6bfa893be9 392 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 147 158 1.7E-12 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CDC59_RS10445 4a07d99557bc47a6cc97bd6bfa893be9 392 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 224 237 1.7E-12 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CDC59_RS10445 4a07d99557bc47a6cc97bd6bfa893be9 392 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 197 214 1.7E-12 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CDC59_RS10445 4a07d99557bc47a6cc97bd6bfa893be9 392 Gene3D G3DSA:3.40.710.10 23 387 3.3E-44 T 29-03-2018 CDC59_RS10445 4a07d99557bc47a6cc97bd6bfa893be9 392 SUPERFAMILY SSF56601 119 357 4.8E-56 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CDC59_RS10445 4a07d99557bc47a6cc97bd6bfa893be9 392 SUPERFAMILY SSF56601 21 39 4.8E-56 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CDC59_RS10445 4a07d99557bc47a6cc97bd6bfa893be9 392 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 117 339 1.2E-56 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CDC59_RS09765 c0f3b400ec8f4fa0719ebc67a7fb7580 311 PRINTS PR00412 Epoxide hydrolase signature 122 135 1.2E-18 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CDC59_RS09765 c0f3b400ec8f4fa0719ebc67a7fb7580 311 PRINTS PR00412 Epoxide hydrolase signature 108 121 1.2E-18 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CDC59_RS09765 c0f3b400ec8f4fa0719ebc67a7fb7580 311 PRINTS PR00412 Epoxide hydrolase signature 43 61 1.2E-18 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CDC59_RS09765 c0f3b400ec8f4fa0719ebc67a7fb7580 311 PRINTS PR00412 Epoxide hydrolase signature 287 309 1.2E-18 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CDC59_RS09765 c0f3b400ec8f4fa0719ebc67a7fb7580 311 PRINTS PR00412 Epoxide hydrolase signature 254 270 1.2E-18 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CDC59_RS09765 c0f3b400ec8f4fa0719ebc67a7fb7580 311 PRINTS PR00111 Alpha/beta hydrolase fold signature 62 77 4.3E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS09765 c0f3b400ec8f4fa0719ebc67a7fb7580 311 PRINTS PR00111 Alpha/beta hydrolase fold signature 122 135 4.3E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS09765 c0f3b400ec8f4fa0719ebc67a7fb7580 311 PRINTS PR00111 Alpha/beta hydrolase fold signature 108 121 4.3E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS09765 c0f3b400ec8f4fa0719ebc67a7fb7580 311 Gene3D G3DSA:3.40.50.1820 20 311 1.6E-53 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS09765 c0f3b400ec8f4fa0719ebc67a7fb7580 311 Pfam PF00561 alpha/beta hydrolase fold 37 298 9.5E-27 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS09765 c0f3b400ec8f4fa0719ebc67a7fb7580 311 SUPERFAMILY SSF53474 17 310 7.96E-67 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS22060 4b8282e9c8b62b15d3ead0da4e73b9ac 238 Gene3D G3DSA:3.40.50.300 3 122 1.7E-12 T 29-03-2018 CDC59_RS22060 4b8282e9c8b62b15d3ead0da4e73b9ac 238 Pfam PF01745 Isopentenyl transferase 4 235 2.2E-103 T 29-03-2018 IPR002648 Adenylate dimethylallyltransferase GO:0004161|GO:0009058 KEGG: 00908+2.5.1.27|MetaCyc: PWY-2681 CDC59_RS22060 4b8282e9c8b62b15d3ead0da4e73b9ac 238 PIRSF PIRSF000507 3 238 6.5E-94 T 29-03-2018 IPR002648 Adenylate dimethylallyltransferase GO:0004161|GO:0009058 KEGG: 00908+2.5.1.27|MetaCyc: PWY-2681 CDC59_RS22060 4b8282e9c8b62b15d3ead0da4e73b9ac 238 SUPERFAMILY SSF52540 5 168 1.4E-6 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS23140 22187466e3b719510ea8d1c7c7b0ffc0 537 SUPERFAMILY SSF52096 156 313 2.03E-18 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CDC59_RS23140 22187466e3b719510ea8d1c7c7b0ffc0 537 Gene3D G3DSA:3.90.226.10 151 455 6.9E-12 T 29-03-2018 CDC59_RS06000 e26f82043ea98c98600275cd8e788250 257 SMART SM00382 36 229 1.8E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS06000 e26f82043ea98c98600275cd8e788250 257 Gene3D G3DSA:3.40.50.300 2 256 1.1E-51 T 29-03-2018 CDC59_RS06000 e26f82043ea98c98600275cd8e788250 257 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 230 252 4.5E-10 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CDC59_RS06000 e26f82043ea98c98600275cd8e788250 257 SUPERFAMILY SSF52540 10 252 4.65E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS06000 e26f82043ea98c98600275cd8e788250 257 Pfam PF00005 ABC transporter 29 182 7.6E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS03080 6ef077d38849149bc9a7ce76cf4cb43d 211 Pfam PF03232 Ubiquinone biosynthesis protein COQ7 51 210 4.7E-44 T 29-03-2018 IPR011566 Ubiquinone biosynthesis protein Coq7 GO:0006744|GO:0055114 Reactome: R-HSA-2142789 CDC59_RS03080 6ef077d38849149bc9a7ce76cf4cb43d 211 SUPERFAMILY SSF47240 46 126 1.71E-17 T 29-03-2018 IPR009078 Ferritin-like superfamily CDC59_RS03080 6ef077d38849149bc9a7ce76cf4cb43d 211 Hamap MF_01658 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase [coq7]. 6 211 33.004 T 29-03-2018 IPR011566 Ubiquinone biosynthesis protein Coq7 GO:0006744|GO:0055114 Reactome: R-HSA-2142789 CDC59_RS03080 6ef077d38849149bc9a7ce76cf4cb43d 211 Gene3D G3DSA:1.20.1260.10 41 184 6.2E-22 T 29-03-2018 IPR012347 Ferritin-related CDC59_RS17690 c2f0df344eb0a575a8b070f46c56c909 342 SUPERFAMILY SSF50022 2 111 4.32E-32 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CDC59_RS17690 c2f0df344eb0a575a8b070f46c56c909 342 Pfam PF00355 Rieske [2Fe-2S] domain 7 86 1.5E-17 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CDC59_RS17690 c2f0df344eb0a575a8b070f46c56c909 342 SUPERFAMILY SSF55961 102 341 4.4E-53 T 29-03-2018 CDC59_RS17690 c2f0df344eb0a575a8b070f46c56c909 342 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 47 69 - T 29-03-2018 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0016705|GO:0051537|GO:0055114 CDC59_RS17690 c2f0df344eb0a575a8b070f46c56c909 342 Gene3D G3DSA:3.90.380.10 107 342 2.7E-43 T 29-03-2018 CDC59_RS17690 c2f0df344eb0a575a8b070f46c56c909 342 Gene3D G3DSA:2.102.10.10 2 106 7.0E-25 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CDC59_RS21880 64dde2fb90d9f77dce6e4487ec625640 245 Gene3D G3DSA:3.40.50.2300 3 125 2.0E-37 T 29-03-2018 CDC59_RS21880 64dde2fb90d9f77dce6e4487ec625640 245 Pfam PF00072 Response regulator receiver domain 6 116 6.0E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS21880 64dde2fb90d9f77dce6e4487ec625640 245 SMART SM00448 4 115 5.9E-40 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS21880 64dde2fb90d9f77dce6e4487ec625640 245 SUPERFAMILY SSF52172 2 127 6.83E-41 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS21880 64dde2fb90d9f77dce6e4487ec625640 245 SMART SM00862 154 230 2.2E-20 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDC59_RS21880 64dde2fb90d9f77dce6e4487ec625640 245 Gene3D G3DSA:1.10.10.10 126 237 1.7E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS21880 64dde2fb90d9f77dce6e4487ec625640 245 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 230 3.9E-21 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDC59_RS21880 64dde2fb90d9f77dce6e4487ec625640 245 SUPERFAMILY SSF46894 132 232 1.16E-24 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CDC59_RS09820 a46f4aa1dd2d9b51ba25956353de49f8 336 Gene3D G3DSA:1.20.272.10 190 336 1.1E-15 T 29-03-2018 CDC59_RS09820 a46f4aa1dd2d9b51ba25956353de49f8 336 Gene3D G3DSA:3.40.50.300 12 181 1.5E-23 T 29-03-2018 CDC59_RS09820 a46f4aa1dd2d9b51ba25956353de49f8 336 SUPERFAMILY SSF52540 7 204 2.49E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS09820 a46f4aa1dd2d9b51ba25956353de49f8 336 Pfam PF13177 DNA polymerase III, delta subunit 18 182 2.5E-39 T 29-03-2018 CDC59_RS09820 a46f4aa1dd2d9b51ba25956353de49f8 336 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 16 209 1.5E-60 T 29-03-2018 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CDC59_RS11875 bc14e998def72efc576c89857b34a4b0 338 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 183 326 2.1E-64 T 29-03-2018 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CDC59_RS11875 bc14e998def72efc576c89857b34a4b0 338 PIRSF PIRSF000116 201 332 1.4E-14 T 29-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CDC59_RS11875 bc14e998def72efc576c89857b34a4b0 338 PIRSF PIRSF000116 2 205 4.9E-50 T 29-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CDC59_RS11875 bc14e998def72efc576c89857b34a4b0 338 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 14 177 1.9E-72 T 29-03-2018 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CDC59_RS11875 bc14e998def72efc576c89857b34a4b0 338 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 14 326 7.9E-132 T 29-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CDC59_RS11875 bc14e998def72efc576c89857b34a4b0 338 SUPERFAMILY SSF51735 1 182 1.35E-73 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS11875 bc14e998def72efc576c89857b34a4b0 338 SUPERFAMILY SSF48179 183 332 2.04E-70 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CDC59_RS11875 bc14e998def72efc576c89857b34a4b0 338 Gene3D G3DSA:1.10.1040.10 61 330 2.1E-112 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CDC59_RS11875 bc14e998def72efc576c89857b34a4b0 338 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 1 328 45.204 T 29-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CDC59_RS15285 47594a52a51b895b201a4171d513a066 299 PIRSF PIRSF028200 1 279 1.4E-96 T 29-03-2018 IPR016875 Uncharacterised conserved protein UCP028200 CDC59_RS11575 4fe7ee8a923d21dc5fb900a208efc4b5 259 SUPERFAMILY SSF52096 4 259 4.1E-73 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CDC59_RS11575 4fe7ee8a923d21dc5fb900a208efc4b5 259 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 102 122 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CDC59_RS11575 4fe7ee8a923d21dc5fb900a208efc4b5 259 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 258 1.4E-52 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CDC59_RS11575 4fe7ee8a923d21dc5fb900a208efc4b5 259 Gene3D G3DSA:3.90.226.10 4 218 1.1E-58 T 29-03-2018 CDC59_RS11575 4fe7ee8a923d21dc5fb900a208efc4b5 259 Gene3D G3DSA:1.10.12.10 219 259 5.0E-13 T 29-03-2018 IPR014748 Crontonase, C-terminal CDC59_RS15305 1f6371de0aa9a2c32504c6e59b0f333c 438 SUPERFAMILY SSF56176 6 182 4.35E-33 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CDC59_RS15305 1f6371de0aa9a2c32504c6e59b0f333c 438 Gene3D G3DSA:3.30.465.10 58 184 4.5E-26 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CDC59_RS15305 1f6371de0aa9a2c32504c6e59b0f333c 438 Pfam PF01565 FAD binding domain 24 150 1.3E-18 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CDC59_RS07585 26d673cbe86f84f8ad747100c798d893 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 69 5.2E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS07585 26d673cbe86f84f8ad747100c798d893 306 Gene3D G3DSA:3.40.190.10 93 182 6.7E-22 T 29-03-2018 CDC59_RS07585 26d673cbe86f84f8ad747100c798d893 306 SUPERFAMILY SSF46785 5 114 1.69E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS07585 26d673cbe86f84f8ad747100c798d893 306 Pfam PF03466 LysR substrate binding domain 90 294 3.1E-46 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS07585 26d673cbe86f84f8ad747100c798d893 306 SUPERFAMILY SSF53850 89 298 3.57E-44 T 29-03-2018 CDC59_RS07585 26d673cbe86f84f8ad747100c798d893 306 Gene3D G3DSA:1.10.10.10 3 90 8.3E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS07585 26d673cbe86f84f8ad747100c798d893 306 Gene3D G3DSA:3.40.190.10 183 266 6.3E-20 T 29-03-2018 CDC59_RS07585 26d673cbe86f84f8ad747100c798d893 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 36 7.1E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS07585 26d673cbe86f84f8ad747100c798d893 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 7.1E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS07585 26d673cbe86f84f8ad747100c798d893 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 46 7.1E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS05930 8c76d4ee5c3fbfd4645dc2bac25a5fa9 249 Gene3D G3DSA:3.40.50.300 1 244 6.9E-72 T 29-03-2018 CDC59_RS05930 8c76d4ee5c3fbfd4645dc2bac25a5fa9 249 SUPERFAMILY SSF52540 3 237 5.2E-79 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS05930 8c76d4ee5c3fbfd4645dc2bac25a5fa9 249 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS05930 8c76d4ee5c3fbfd4645dc2bac25a5fa9 249 Pfam PF00005 ABC transporter 21 167 3.2E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS05930 8c76d4ee5c3fbfd4645dc2bac25a5fa9 249 PIRSF PIRSF039085 1 243 3.0E-105 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CDC59_RS05930 8c76d4ee5c3fbfd4645dc2bac25a5fa9 249 SMART SM00382 28 215 9.3E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS07665 78a91c9f153957de3e9fbb8b3ee1cce2 304 SUPERFAMILY SSF56235 2 240 2.36E-31 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CDC59_RS07665 78a91c9f153957de3e9fbb8b3ee1cce2 304 PIRSF PIRSF009120 1 250 2.6E-121 T 29-03-2018 IPR016545 Uncharacterised conserved protein UCP009120, proteasome-type protease, Sll0069 CDC59_RS07665 78a91c9f153957de3e9fbb8b3ee1cce2 304 Gene3D G3DSA:3.60.20.10 2 223 2.0E-35 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CDC59_RS10875 c64c12498e6506a1a8810d0e33374c9e 157 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 75 4.2E-10 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CDC59_RS10875 c64c12498e6506a1a8810d0e33374c9e 157 PIRSF PIRSF000709 4 80 6.6E-5 T 29-03-2018 CDC59_RS10875 c64c12498e6506a1a8810d0e33374c9e 157 Gene3D G3DSA:3.40.50.1240 1 156 1.2E-21 T 29-03-2018 IPR029033 Histidine phosphatase superfamily CDC59_RS10875 c64c12498e6506a1a8810d0e33374c9e 157 SUPERFAMILY SSF53254 2 138 1.83E-21 T 29-03-2018 IPR029033 Histidine phosphatase superfamily CDC59_RS10875 c64c12498e6506a1a8810d0e33374c9e 157 TIGRFAM TIGR00249 sixA: phosphohistidine phosphatase SixA 1 131 1.3E-22 T 29-03-2018 IPR004449 Phosphohistidine phosphatase SixA GO:0005737|GO:0006464|GO:0008969 CDC59_RS10875 c64c12498e6506a1a8810d0e33374c9e 157 SMART SM00855 2 113 3.4E-7 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CDC59_RS15815 8bde55f678e01c1e163d209cfb11ec13 380 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 333 357 - T 29-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 CDC59_RS15815 8bde55f678e01c1e163d209cfb11ec13 380 Pfam PF01098 Cell cycle protein 22 376 8.8E-98 T 29-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 CDC59_RS15815 8bde55f678e01c1e163d209cfb11ec13 380 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 18 375 1.3E-125 T 29-03-2018 IPR011923 Rod shape-determining protein RodA GO:0008360|GO:0016021 CDC59_RS21100 9fcc29eacff213188f4a90afbb1afae2 1141 Pfam PF01841 Transglutaminase-like superfamily 133 246 6.9E-18 T 29-03-2018 IPR002931 Transglutaminase-like CDC59_RS21100 9fcc29eacff213188f4a90afbb1afae2 1141 Pfam PF09899 Putative amidoligase enzyme (DUF2126) 276 1139 0.0 T 29-03-2018 IPR018667 Domain of unknown function DUF2126 CDC59_RS21100 9fcc29eacff213188f4a90afbb1afae2 1141 Gene3D G3DSA:3.90.260.10 171 272 2.5E-5 T 29-03-2018 IPR002931 Transglutaminase-like CDC59_RS21100 9fcc29eacff213188f4a90afbb1afae2 1141 SMART SM00460 172 248 3.3E-17 T 29-03-2018 IPR002931 Transglutaminase-like CDC59_RS21100 9fcc29eacff213188f4a90afbb1afae2 1141 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 6 84 1.1E-27 T 29-03-2018 IPR013589 Bacterial transglutaminase-like, N-terminal CDC59_RS21100 9fcc29eacff213188f4a90afbb1afae2 1141 SUPERFAMILY SSF54001 8 337 1.82E-72 T 29-03-2018 CDC59_RS11555 8fc760c434974441fd18803a5e7ad052 161 Gene3D G3DSA:3.40.50.1010 9 145 8.5E-15 T 29-03-2018 IPR029060 PIN domain-like CDC59_RS11555 8fc760c434974441fd18803a5e7ad052 161 SMART SM00670 9 130 0.0027 T 29-03-2018 IPR002716 PIN domain CDC59_RS11555 8fc760c434974441fd18803a5e7ad052 161 SUPERFAMILY SSF88723 10 131 5.05E-13 T 29-03-2018 IPR029060 PIN domain-like CDC59_RS11555 8fc760c434974441fd18803a5e7ad052 161 Pfam PF13470 PIN domain 10 127 2.2E-31 T 29-03-2018 IPR002716 PIN domain CDC59_RS11555 8fc760c434974441fd18803a5e7ad052 161 TIGRFAM TIGR00305 TIGR00305: putative toxin-antitoxin system toxin component, PIN family 10 131 8.4E-9 T 29-03-2018 IPR002850 PIN family, putative toxin-antitoxin system toxin component CDC59_RS00160 53f244a2b5b615c28a15781839734a99 403 SUPERFAMILY SSF53474 36 392 1.99E-103 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS00160 53f244a2b5b615c28a15781839734a99 403 Gene3D G3DSA:3.40.50.1820 53 397 2.8E-33 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS00160 53f244a2b5b615c28a15781839734a99 403 Hamap MF_00296 Homoserine O-acetyltransferase [metX]. 31 396 48.474 T 29-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 CDC59_RS00160 53f244a2b5b615c28a15781839734a99 403 TIGRFAM TIGR01392 homoserO_Ac_trn: homoserine O-acetyltransferase 45 393 1.1E-140 T 29-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 CDC59_RS00160 53f244a2b5b615c28a15781839734a99 403 PIRSF PIRSF000443 12 403 1.1E-143 T 29-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 CDC59_RS00160 53f244a2b5b615c28a15781839734a99 403 Pfam PF00561 alpha/beta hydrolase fold 74 383 3.0E-36 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS12430 83567cd060a074af817a4e9edb298e4b 123 Pfam PF01903 CbiX 11 115 1.8E-24 T 29-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 CDC59_RS12430 83567cd060a074af817a4e9edb298e4b 123 Gene3D G3DSA:3.40.50.1400 1 123 3.3E-29 T 29-03-2018 CDC59_RS12430 83567cd060a074af817a4e9edb298e4b 123 SUPERFAMILY SSF53800 5 120 1.96E-28 T 29-03-2018 CDC59_RS10330 647cc711224a809e5428139e9e140a6e 598 Gene3D G3DSA:3.40.50.1820 234 568 2.2E-21 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS10330 647cc711224a809e5428139e9e140a6e 598 TIGRFAM TIGR01838 PHA_synth_I: poly(R)-hydroxyalkanoic acid synthase, class I 73 596 7.7E-232 T 29-03-2018 IPR010963 Poly(R)-hydroxyalkanoic acid synthase, class I GO:0005737|GO:0016746|GO:0042619 CDC59_RS10330 647cc711224a809e5428139e9e140a6e 598 SUPERFAMILY SSF53474 232 534 5.92E-41 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS10330 647cc711224a809e5428139e9e140a6e 598 Pfam PF07167 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus 107 273 4.1E-70 T 29-03-2018 IPR010941 Poly-beta-hydroxybutyrate polymerase, N-terminal domain GO:0042619 CDC59_RS17055 d65fbb67f5b57d28cb614cd4efef1322 316 Gene3D G3DSA:1.20.1330.10 38 289 4.1E-17 T 29-03-2018 CDC59_RS17055 d65fbb67f5b57d28cb614cd4efef1322 316 TIGRFAM TIGR02550 flagell_flgL: flagellar hook-associated protein 3 2 193 5.8E-55 T 29-03-2018 IPR013384 Flagellar hook-associated protein 3 GO:0009424|GO:0071973 CDC59_RS17055 d65fbb67f5b57d28cb614cd4efef1322 316 SUPERFAMILY SSF64518 1 314 1.44E-50 T 29-03-2018 CDC59_RS17055 d65fbb67f5b57d28cb614cd4efef1322 316 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 140 8.5E-13 T 29-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CDC59_RS17055 d65fbb67f5b57d28cb614cd4efef1322 316 Pfam PF00700 Bacterial flagellin C-terminal helical region 234 314 3.4E-5 T 29-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CDC59_RS23650 eb34b7a6e1fd2bad095486bf2129a621 274 Pfam PF08241 Methyltransferase domain 66 164 6.4E-21 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CDC59_RS23650 eb34b7a6e1fd2bad095486bf2129a621 274 Gene3D G3DSA:3.40.50.150 10 274 9.9E-40 T 29-03-2018 CDC59_RS23650 eb34b7a6e1fd2bad095486bf2129a621 274 SUPERFAMILY SSF53335 39 274 4.14E-49 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS06525 b087cd45bb2fb0991ff7d5bf718c3f33 354 Gene3D G3DSA:2.40.160.10 13 354 1.7E-60 T 29-03-2018 CDC59_RS06525 b087cd45bb2fb0991ff7d5bf718c3f33 354 Pfam PF13609 Gram-negative porin 12 336 1.5E-61 T 29-03-2018 CDC59_RS06525 b087cd45bb2fb0991ff7d5bf718c3f33 354 SUPERFAMILY SSF56935 27 354 4.88E-70 T 29-03-2018 CDC59_RS13695 4fda200344f5e7e9c69e39a8c1951196 423 SUPERFAMILY SSF51905 365 422 9.71E-42 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS13695 4fda200344f5e7e9c69e39a8c1951196 423 SUPERFAMILY SSF51905 14 64 9.71E-42 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS13695 4fda200344f5e7e9c69e39a8c1951196 423 SUPERFAMILY SSF51905 117 278 9.71E-42 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS13695 4fda200344f5e7e9c69e39a8c1951196 423 Gene3D G3DSA:3.50.50.60 2 423 2.1E-38 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS13695 4fda200344f5e7e9c69e39a8c1951196 423 Pfam PF01266 FAD dependent oxidoreductase 14 404 3.6E-55 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CDC59_RS13695 4fda200344f5e7e9c69e39a8c1951196 423 SUPERFAMILY SSF54373 280 365 5.49E-14 T 29-03-2018 CDC59_RS13110 c84f2fcbab7011e7e9ad705f1e27b6bd 298 Pfam PF02424 ApbE family 16 272 1.4E-42 T 29-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 CDC59_RS13110 c84f2fcbab7011e7e9ad705f1e27b6bd 298 Gene3D G3DSA:3.10.520.10 16 292 3.2E-30 T 29-03-2018 CDC59_RS13110 c84f2fcbab7011e7e9ad705f1e27b6bd 298 SUPERFAMILY SSF143631 9 278 1.57E-59 T 29-03-2018 IPR003374 ApbE-like domain CDC59_RS15200 5620a409fc517e438809aa1fc0df4930 303 Gene3D G3DSA:3.40.1090.10 2 204 5.1E-46 T 29-03-2018 CDC59_RS15200 5620a409fc517e438809aa1fc0df4930 303 Pfam PF01734 Patatin-like phospholipase 10 178 4.8E-29 T 29-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 CDC59_RS15200 5620a409fc517e438809aa1fc0df4930 303 SUPERFAMILY SSF52151 7 198 4.36E-54 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CDC59_RS00040 d22e97b9b474aaa2664cbd8c741c0773 107 Gene3D G3DSA:3.40.50.2300 2 40 9.4E-9 T 29-03-2018 CDC59_RS00040 d22e97b9b474aaa2664cbd8c741c0773 107 Gene3D G3DSA:3.40.50.2300 41 101 0.0052 T 29-03-2018 CDC59_RS00040 d22e97b9b474aaa2664cbd8c741c0773 107 SUPERFAMILY SSF52788 1 103 3.14E-18 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CDC59_RS00040 d22e97b9b474aaa2664cbd8c741c0773 107 PIRSF PIRSF029416 1 107 3.3E-52 T 29-03-2018 IPR016919 Uncharacterised conserved protein UCP029416, tyrosine-protein phosphatase, Mlr4629 CDC59_RS00275 edfa6a33fdcd4d4836d86267186576fe 201 Gene3D G3DSA:3.40.1000.10 23 200 1.9E-6 T 29-03-2018 CDC59_RS12135 94245218662409c7b662002ae3b3e4dc 175 SUPERFAMILY SSF81342 5 174 2.04E-34 T 29-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 CDC59_RS12135 94245218662409c7b662002ae3b3e4dc 175 Gene3D G3DSA:1.20.950.20 2 175 1.3E-28 T 29-03-2018 CDC59_RS12135 94245218662409c7b662002ae3b3e4dc 175 Pfam PF01292 Prokaryotic cytochrome b561 10 170 1.2E-21 T 29-03-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 CDC59_RS20380 0baf81bac0a180dc5191a18a4c2f178f 250 Gene3D G3DSA:3.40.50.300 36 229 5.9E-7 T 29-03-2018 CDC59_RS20380 0baf81bac0a180dc5191a18a4c2f178f 250 SUPERFAMILY SSF52540 96 189 3.18E-17 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS20380 0baf81bac0a180dc5191a18a4c2f178f 250 SUPERFAMILY SSF52540 25 65 3.18E-17 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS20380 0baf81bac0a180dc5191a18a4c2f178f 250 Pfam PF06414 Zeta toxin 23 209 3.0E-7 T 29-03-2018 IPR010488 Zeta toxin domain GO:0005524|GO:0016301 CDC59_RS20380 0baf81bac0a180dc5191a18a4c2f178f 250 Gene3D G3DSA:3.40.50.300 8 35 0.0029 T 29-03-2018 CDC59_RS15925 2a844d08121ec6151870ce51f8d844ce 178 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 6 177 40.453 T 29-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 CDC59_RS15925 2a844d08121ec6151870ce51f8d844ce 178 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 7 177 2.8E-82 T 29-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 CDC59_RS15925 2a844d08121ec6151870ce51f8d844ce 178 Gene3D G3DSA:3.60.20.10 7 178 3.0E-32 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CDC59_RS15925 2a844d08121ec6151870ce51f8d844ce 178 PIRSF PIRSF039093 1 178 3.7E-84 T 29-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 CDC59_RS15925 2a844d08121ec6151870ce51f8d844ce 178 Pfam PF00227 Proteasome subunit 5 176 1.7E-23 T 29-03-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 CDC59_RS15925 2a844d08121ec6151870ce51f8d844ce 178 SUPERFAMILY SSF56235 3 177 1.93E-57 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CDC59_RS23245 dae456418ae873356b945f347638072d 846 Gene3D G3DSA:2.160.20.10 642 836 0.008 T 29-03-2018 IPR012334 Pectin lyase fold CDC59_RS23245 dae456418ae873356b945f347638072d 846 Gene3D G3DSA:2.160.20.10 33 327 2.2E-37 T 29-03-2018 IPR012334 Pectin lyase fold CDC59_RS23245 dae456418ae873356b945f347638072d 846 Pfam PF05860 haemagglutination activity domain 29 143 3.8E-28 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal CDC59_RS23245 dae456418ae873356b945f347638072d 846 SMART SM00912 44 144 5.2E-17 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal CDC59_RS23245 dae456418ae873356b945f347638072d 846 TIGRFAM TIGR01901 adhes_NPXG: filamentous hemagglutinin family N-terminal domain 61 139 2.7E-21 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal CDC59_RS23245 dae456418ae873356b945f347638072d 846 SUPERFAMILY SSF51126 36 292 3.45E-35 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CDC59_RS01845 f8544382fb0eceaedd9b5fed1ce35049 295 Gene3D G3DSA:1.10.760.10 51 169 1.1E-10 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS01845 f8544382fb0eceaedd9b5fed1ce35049 295 Gene3D G3DSA:1.10.760.10 215 294 9.4E-12 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS01845 f8544382fb0eceaedd9b5fed1ce35049 295 SUPERFAMILY SSF46626 219 291 1.52E-16 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS01845 f8544382fb0eceaedd9b5fed1ce35049 295 SUPERFAMILY SSF46626 80 158 5.87E-16 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS01845 f8544382fb0eceaedd9b5fed1ce35049 295 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 216 290 1.8E-17 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS01845 f8544382fb0eceaedd9b5fed1ce35049 295 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 80 156 4.2E-15 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS01845 f8544382fb0eceaedd9b5fed1ce35049 295 PRINTS PR00607 Class IE cytochrome C signature 266 278 5.9E-15 T 29-03-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 CDC59_RS01845 f8544382fb0eceaedd9b5fed1ce35049 295 PRINTS PR00607 Class IE cytochrome C signature 238 248 5.9E-15 T 29-03-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 CDC59_RS01845 f8544382fb0eceaedd9b5fed1ce35049 295 PRINTS PR00607 Class IE cytochrome C signature 227 238 5.9E-15 T 29-03-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 CDC59_RS01845 f8544382fb0eceaedd9b5fed1ce35049 295 PRINTS PR00607 Class IE cytochrome C signature 280 291 5.9E-15 T 29-03-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 CDC59_RS17555 4710fb506b8cfb137ae1d51a311af2a0 373 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 147 163 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site CDC59_RS17555 4710fb506b8cfb137ae1d51a311af2a0 373 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 150 228 6.3E-18 T 29-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CDC59_RS17555 4710fb506b8cfb137ae1d51a311af2a0 373 Gene3D G3DSA:3.40.47.10 220 373 6.9E-26 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS17555 4710fb506b8cfb137ae1d51a311af2a0 373 Gene3D G3DSA:3.40.47.10 1 219 1.2E-31 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS17555 4710fb506b8cfb137ae1d51a311af2a0 373 SUPERFAMILY SSF53901 2 372 1.36E-43 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS17555 4710fb506b8cfb137ae1d51a311af2a0 373 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 282 371 5.3E-22 T 29-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CDC59_RS13520 83a0e5348dce8b0702b5ac56923b4016 349 SUPERFAMILY SSF46689 6 76 1.13E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS13520 83a0e5348dce8b0702b5ac56923b4016 349 Gene3D G3DSA:1.10.357.10 53 212 1.4E-27 T 29-03-2018 CDC59_RS13520 83a0e5348dce8b0702b5ac56923b4016 349 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 58 1.0E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDC59_RS13520 83a0e5348dce8b0702b5ac56923b4016 349 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 2.0E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDC59_RS13520 83a0e5348dce8b0702b5ac56923b4016 349 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 2.0E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDC59_RS13520 83a0e5348dce8b0702b5ac56923b4016 349 Gene3D G3DSA:1.10.10.60 1 52 6.0E-15 T 29-03-2018 CDC59_RS13520 83a0e5348dce8b0702b5ac56923b4016 349 ProSitePatterns PS01081 TetR-type HTH domain signature. 25 56 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CDC59_RS13520 83a0e5348dce8b0702b5ac56923b4016 349 SUPERFAMILY SSF48498 84 214 2.71E-37 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CDC59_RS03850 23609aea782912985607723c28d60a9f 291 TIGRFAM TIGR01474 ubiA_proteo: 4-hydroxybenzoate polyprenyl transferase 12 287 6.9E-99 T 29-03-2018 IPR006370 4-hydroxybenzoate polyprenyltransferase GO:0004659|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 CDC59_RS03850 23609aea782912985607723c28d60a9f 291 Hamap MF_01635 4-hydroxybenzoate octaprenyltransferase [ubiA]. 6 289 28.489 T 29-03-2018 IPR031103 4-hydroxybenzoate octaprenyltransferase GO:0004659|GO:0006744|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 CDC59_RS03850 23609aea782912985607723c28d60a9f 291 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 68 90 - T 29-03-2018 IPR030470 UbiA prenyltransferase conserved site CDC59_RS03850 23609aea782912985607723c28d60a9f 291 Pfam PF01040 UbiA prenyltransferase family 29 274 1.5E-57 T 29-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 CDC59_RS15610 20f98125fd7a5a51968b96cf8aaba650 71 SUPERFAMILY SSF54285 3 71 8.77E-11 T 29-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CDC59_RS15610 20f98125fd7a5a51968b96cf8aaba650 71 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 5 71 2.3E-10 T 29-03-2018 IPR010035 ThiS, thiamine-biosynthesis CDC59_RS15610 20f98125fd7a5a51968b96cf8aaba650 71 Pfam PF02597 ThiS family 9 71 1.6E-12 T 29-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 CDC59_RS15610 20f98125fd7a5a51968b96cf8aaba650 71 Gene3D G3DSA:3.10.20.30 3 71 9.9E-14 T 29-03-2018 IPR012675 Beta-grasp domain CDC59_RS01125 08bedeb99aabeacd9e354987ac0a3e78 118 SUPERFAMILY SSF52833 2 117 6.19E-29 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS01125 08bedeb99aabeacd9e354987ac0a3e78 118 Pfam PF03960 ArsC family 4 116 9.6E-17 T 29-03-2018 IPR006660 Arsenate reductase-like CDC59_RS01125 08bedeb99aabeacd9e354987ac0a3e78 118 Gene3D G3DSA:3.40.30.10 1 117 1.1E-32 T 29-03-2018 CDC59_RS01125 08bedeb99aabeacd9e354987ac0a3e78 118 TIGRFAM TIGR00014 arsC: arsenate reductase (glutaredoxin) 2 115 3.6E-34 T 29-03-2018 IPR006659 Arsenate reductase GO:0008794|GO:0055114 MetaCyc: PWY-4202|MetaCyc: PWY-4621 CDC59_RS06220 7354dc147457bdcdcdd58d5cb5e00968 306 Pfam PF00535 Glycosyl transferase family 2 3 111 1.2E-15 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CDC59_RS06220 7354dc147457bdcdcdd58d5cb5e00968 306 Gene3D G3DSA:3.90.550.10 1 289 1.7E-28 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDC59_RS06220 7354dc147457bdcdcdd58d5cb5e00968 306 SUPERFAMILY SSF53448 1 235 6.1E-32 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDC59_RS11630 8e843dde393559344f2ef56cff7b3806 202 Pfam PF01810 LysE type translocator 13 198 5.2E-37 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CDC59_RS20705 1fc5eb1588dee01ce40694823edba4b1 626 Pfam PF02515 CoA-transferase family III 307 594 1.2E-55 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 CDC59_RS20705 1fc5eb1588dee01ce40694823edba4b1 626 Pfam PF02515 CoA-transferase family III 66 280 1.5E-15 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 CDC59_RS20705 1fc5eb1588dee01ce40694823edba4b1 626 SUPERFAMILY SSF89796 66 286 4.06E-26 T 29-03-2018 IPR023606 CoA-transferase family III domain CDC59_RS20705 1fc5eb1588dee01ce40694823edba4b1 626 Gene3D G3DSA:3.40.50.10540 64 291 3.7E-24 T 29-03-2018 IPR023606 CoA-transferase family III domain CDC59_RS20705 1fc5eb1588dee01ce40694823edba4b1 626 Gene3D G3DSA:3.40.50.10540 301 623 6.8E-63 T 29-03-2018 IPR023606 CoA-transferase family III domain CDC59_RS20705 1fc5eb1588dee01ce40694823edba4b1 626 SUPERFAMILY SSF89796 303 605 2.35E-62 T 29-03-2018 IPR023606 CoA-transferase family III domain CDC59_RS15255 68f937fc67dad5048b63c741104bd325 352 PRINTS PR00108 Thymidylate synthase family signature 49 70 5.0E-9 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CDC59_RS15255 68f937fc67dad5048b63c741104bd325 352 PRINTS PR00108 Thymidylate synthase family signature 165 191 5.0E-9 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CDC59_RS15255 68f937fc67dad5048b63c741104bd325 352 PRINTS PR00108 Thymidylate synthase family signature 203 220 5.0E-9 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CDC59_RS15255 68f937fc67dad5048b63c741104bd325 352 PRINTS PR00108 Thymidylate synthase family signature 116 135 5.0E-9 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CDC59_RS15255 68f937fc67dad5048b63c741104bd325 352 Pfam PF00303 Thymidylate synthase 53 240 2.3E-28 T 29-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CDC59_RS15255 68f937fc67dad5048b63c741104bd325 352 Gene3D G3DSA:3.30.572.10 14 261 9.7E-45 T 29-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CDC59_RS15255 68f937fc67dad5048b63c741104bd325 352 SUPERFAMILY SSF55831 22 261 3.01E-52 T 29-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CDC59_RS04085 4dd49d68ed5d17fe9233ea2275041766 214 PRINTS PR00773 GrpE protein signature 85 101 1.3E-24 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CDC59_RS04085 4dd49d68ed5d17fe9233ea2275041766 214 PRINTS PR00773 GrpE protein signature 191 210 1.3E-24 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CDC59_RS04085 4dd49d68ed5d17fe9233ea2275041766 214 PRINTS PR00773 GrpE protein signature 113 128 1.3E-24 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CDC59_RS04085 4dd49d68ed5d17fe9233ea2275041766 214 PRINTS PR00773 GrpE protein signature 165 180 1.3E-24 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CDC59_RS04085 4dd49d68ed5d17fe9233ea2275041766 214 Pfam PF01025 GrpE 56 211 4.1E-46 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CDC59_RS04085 4dd49d68ed5d17fe9233ea2275041766 214 SUPERFAMILY SSF51064 158 212 1.7E-17 T 29-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 CDC59_RS04085 4dd49d68ed5d17fe9233ea2275041766 214 SUPERFAMILY SSF58014 63 155 6.8E-22 T 29-03-2018 CDC59_RS04085 4dd49d68ed5d17fe9233ea2275041766 214 Hamap MF_01151 Protein GrpE [grpE]. 12 212 18.97 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CDC59_RS04085 4dd49d68ed5d17fe9233ea2275041766 214 Gene3D G3DSA:3.90.20.20 49 155 1.1E-21 T 29-03-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 CDC59_RS04085 4dd49d68ed5d17fe9233ea2275041766 214 Gene3D G3DSA:2.30.22.10 158 214 1.6E-22 T 29-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 CDC59_RS04085 4dd49d68ed5d17fe9233ea2275041766 214 ProSitePatterns PS01071 grpE protein signature. 168 210 - T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CDC59_RS06130 1a358ff96649de41abec98501a59c059 268 Hamap MF_01527_B GTP cyclohydrolase FolE2 [folE2]. 10 263 37.569 T 29-03-2018 IPR022838 GTP cyclohydrolase FolE2 GO:0003934|GO:0035998 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 CDC59_RS06130 1a358ff96649de41abec98501a59c059 268 Pfam PF02649 Type I GTP cyclohydrolase folE2 10 258 4.1E-92 T 29-03-2018 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 CDC59_RS06130 1a358ff96649de41abec98501a59c059 268 Gene3D G3DSA:3.10.270.10 9 261 9.9E-104 T 29-03-2018 CDC59_RS12345 67f4e4370723a9f3a9d699529609ff85 355 Gene3D G3DSA:1.10.1610.10 1 65 2.5E-30 T 29-03-2018 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CDC59_RS12345 67f4e4370723a9f3a9d699529609ff85 355 Pfam PF02277 Phosphoribosyltransferase 5 342 4.0E-132 T 29-03-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CDC59_RS12345 67f4e4370723a9f3a9d699529609ff85 355 Gene3D G3DSA:3.40.50.10210 66 325 9.6E-104 T 29-03-2018 CDC59_RS12345 67f4e4370723a9f3a9d699529609ff85 355 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 9 342 8.7E-135 T 29-03-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CDC59_RS12345 67f4e4370723a9f3a9d699529609ff85 355 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 7 344 36.821 T 29-03-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CDC59_RS12345 67f4e4370723a9f3a9d699529609ff85 355 SUPERFAMILY SSF52733 3 343 3.4E-119 T 29-03-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CDC59_RS16115 657ac4820e34a181fbf6747c58205d2e 220 PIRSF PIRSF002884 2 220 6.6E-85 T 29-03-2018 IPR007439 Chemotaxis phosphatase, CheZ GO:0003824|GO:0009288|GO:0050920 CDC59_RS16115 657ac4820e34a181fbf6747c58205d2e 220 SUPERFAMILY SSF75708 21 219 2.22E-64 T 29-03-2018 CDC59_RS16115 657ac4820e34a181fbf6747c58205d2e 220 Gene3D G3DSA:1.20.5.590 14 42 5.5E-11 T 29-03-2018 CDC59_RS16115 657ac4820e34a181fbf6747c58205d2e 220 Pfam PF04344 Chemotaxis phosphatase, CheZ 24 220 4.9E-74 T 29-03-2018 IPR007439 Chemotaxis phosphatase, CheZ GO:0003824|GO:0009288|GO:0050920 CDC59_RS16115 657ac4820e34a181fbf6747c58205d2e 220 Gene3D G3DSA:1.10.287.500 44 176 5.9E-18 T 29-03-2018 CDC59_RS01150 aba50628d8f90ac1b3570ddcb5229f30 300 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 97 108 - T 29-03-2018 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CDC59_RS01150 aba50628d8f90ac1b3570ddcb5229f30 300 SUPERFAMILY SSF53790 18 241 4.06E-69 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CDC59_RS01150 aba50628d8f90ac1b3570ddcb5229f30 300 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 20 222 4.3E-28 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CDC59_RS01150 aba50628d8f90ac1b3570ddcb5229f30 300 PIRSF PIRSF005917 9 297 5.7E-90 T 29-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CDC59_RS01150 aba50628d8f90ac1b3570ddcb5229f30 300 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 19 243 32.752 T 29-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CDC59_RS01150 aba50628d8f90ac1b3570ddcb5229f30 300 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 20 293 2.6E-66 T 29-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CDC59_RS01150 aba50628d8f90ac1b3570ddcb5229f30 300 Gene3D G3DSA:3.30.950.10 128 246 3.2E-33 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CDC59_RS01150 aba50628d8f90ac1b3570ddcb5229f30 300 Gene3D G3DSA:3.40.1010.10 17 127 2.2E-36 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CDC59_RS09075 42c1bf56d6feacbe5a522bb1b1c3b0c2 383 Hamap MF_01690 Succinyl-diaminopimelate desuccinylase [dapE]. 2 383 51.385 T 29-03-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 CDC59_RS09075 42c1bf56d6feacbe5a522bb1b1c3b0c2 383 SUPERFAMILY SSF53187 3 186 2.88E-60 T 29-03-2018 CDC59_RS09075 42c1bf56d6feacbe5a522bb1b1c3b0c2 383 SUPERFAMILY SSF53187 300 381 2.88E-60 T 29-03-2018 CDC59_RS09075 42c1bf56d6feacbe5a522bb1b1c3b0c2 383 SUPERFAMILY SSF55031 187 296 5.08E-30 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CDC59_RS09075 42c1bf56d6feacbe5a522bb1b1c3b0c2 383 Pfam PF01546 Peptidase family M20/M25/M40 71 379 5.8E-43 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CDC59_RS09075 42c1bf56d6feacbe5a522bb1b1c3b0c2 383 Gene3D G3DSA:3.30.70.360 190 299 8.4E-29 T 29-03-2018 CDC59_RS09075 42c1bf56d6feacbe5a522bb1b1c3b0c2 383 Gene3D G3DSA:3.40.630.10 2 189 3.4E-31 T 29-03-2018 CDC59_RS09075 42c1bf56d6feacbe5a522bb1b1c3b0c2 383 TIGRFAM TIGR01246 dapE_proteo: succinyl-diaminopimelate desuccinylase 6 381 1.1E-156 T 29-03-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 CDC59_RS09075 42c1bf56d6feacbe5a522bb1b1c3b0c2 383 Pfam PF07687 Peptidase dimerisation domain 183 290 1.3E-26 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CDC59_RS10415 1a86c70a83fda8bbcee62e631fa84da1 257 Pfam PF04376 Arginine-tRNA-protein transferase, N terminus 20 90 2.9E-18 T 29-03-2018 IPR007471 Arginine-tRNA-protein transferase, N-terminal GO:0004057|GO:0016598 MetaCyc: PWY-7799 CDC59_RS10415 1a86c70a83fda8bbcee62e631fa84da1 257 Hamap MF_00689 Putative arginyl-tRNA--protein transferase [ate]. 3 246 44.632 T 29-03-2018 IPR017138 Putative arginyl-tRNA--protein transferase, prokaryotic MetaCyc: PWY-7799 CDC59_RS10415 1a86c70a83fda8bbcee62e631fa84da1 257 SUPERFAMILY SSF55729 86 244 2.15E-14 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDC59_RS10415 1a86c70a83fda8bbcee62e631fa84da1 257 Pfam PF04377 Arginine-tRNA-protein transferase, C terminus 110 237 5.3E-37 T 29-03-2018 IPR007472 Arginine-tRNA-protein transferase, C-terminal GO:0004057|GO:0016598 MetaCyc: PWY-7799 CDC59_RS10415 1a86c70a83fda8bbcee62e631fa84da1 257 PIRSF PIRSF037208 3 255 6.1E-93 T 29-03-2018 IPR017138 Putative arginyl-tRNA--protein transferase, prokaryotic MetaCyc: PWY-7799 CDC59_RS00055 814e72b02d0a9908044f63a1f412deef 70 Pfam PF01165 Ribosomal protein S21 4 56 2.7E-18 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS00055 814e72b02d0a9908044f63a1f412deef 70 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 2 59 3.8E-19 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS00055 814e72b02d0a9908044f63a1f412deef 70 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 19.025 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS00055 814e72b02d0a9908044f63a1f412deef 70 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 1.7E-12 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS00055 814e72b02d0a9908044f63a1f412deef 70 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 1.7E-12 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS00055 814e72b02d0a9908044f63a1f412deef 70 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 1.7E-12 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS00055 814e72b02d0a9908044f63a1f412deef 70 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 1.7E-12 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS00055 814e72b02d0a9908044f63a1f412deef 70 Gene3D G3DSA:1.20.5.1150 16 52 3.6E-15 T 29-03-2018 CDC59_RS00055 814e72b02d0a9908044f63a1f412deef 70 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 15 55 1.0E-14 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS02050 cd5ec358049ff745cca68e8e5f0fc4bc 365 SMART SM00382 34 218 6.1E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS02050 cd5ec358049ff745cca68e8e5f0fc4bc 365 Gene3D G3DSA:2.40.50.140 297 350 2.9E-7 T 29-03-2018 CDC59_RS02050 cd5ec358049ff745cca68e8e5f0fc4bc 365 Gene3D G3DSA:3.40.50.300 1 243 1.2E-57 T 29-03-2018 CDC59_RS02050 cd5ec358049ff745cca68e8e5f0fc4bc 365 SUPERFAMILY SSF50331 243 360 9.72E-17 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CDC59_RS02050 cd5ec358049ff745cca68e8e5f0fc4bc 365 Gene3D G3DSA:2.40.50.100 246 296 2.6E-7 T 29-03-2018 CDC59_RS02050 cd5ec358049ff745cca68e8e5f0fc4bc 365 SUPERFAMILY SSF52540 4 250 3.6E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS02050 cd5ec358049ff745cca68e8e5f0fc4bc 365 Pfam PF08402 TOBE domain 284 353 1.1E-7 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CDC59_RS02050 cd5ec358049ff745cca68e8e5f0fc4bc 365 Pfam PF00005 ABC transporter 25 168 1.1E-23 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS20390 50c152a2bdd44a80f96dacd3c8bb9a02 474 Gene3D G3DSA:3.40.50.1220 301 474 7.3E-81 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CDC59_RS20390 50c152a2bdd44a80f96dacd3c8bb9a02 474 SUPERFAMILY SSF52467 302 474 1.34E-71 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CDC59_RS20390 50c152a2bdd44a80f96dacd3c8bb9a02 474 Pfam PF02233 NAD(P) transhydrogenase beta subunit 7 470 4.9E-187 T 29-03-2018 IPR034300 NADP transhydrogenase beta-like domain KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 CDC59_RS20390 50c152a2bdd44a80f96dacd3c8bb9a02 474 PIRSF PIRSF000204 1 474 2.3E-207 T 29-03-2018 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2 CDC59_RS06800 ca9860b4be2000ee554c910aa56c8354 230 Pfam PF03741 Integral membrane protein TerC family 18 188 9.3E-43 T 29-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 CDC59_RS06800 ca9860b4be2000ee554c910aa56c8354 230 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 16 189 9.7E-67 T 29-03-2018 IPR022301 Integral membrane protein YjbE CDC59_RS17345 cb4e2b3124b1e0e9d28564e2221deb94 407 PRINTS PR01035 Tetracycline resistance protein signature 18 34 1.2E-5 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CDC59_RS17345 cb4e2b3124b1e0e9d28564e2221deb94 407 PRINTS PR01035 Tetracycline resistance protein signature 138 160 1.2E-5 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CDC59_RS17345 cb4e2b3124b1e0e9d28564e2221deb94 407 Gene3D G3DSA:1.20.1250.20 206 402 3.8E-20 T 29-03-2018 CDC59_RS17345 cb4e2b3124b1e0e9d28564e2221deb94 407 Gene3D G3DSA:1.20.1250.20 3 204 9.8E-28 T 29-03-2018 CDC59_RS17345 cb4e2b3124b1e0e9d28564e2221deb94 407 SUPERFAMILY SSF103473 5 393 1.44E-48 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS17345 cb4e2b3124b1e0e9d28564e2221deb94 407 Pfam PF07690 Major Facilitator Superfamily 258 391 1.6E-11 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDC59_RS17345 cb4e2b3124b1e0e9d28564e2221deb94 407 Pfam PF07690 Major Facilitator Superfamily 13 243 3.1E-21 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDC59_RS15705 9652ef963997e3716ea781d305e55b6f 301 Gene3D G3DSA:3.40.190.10 170 301 3.2E-16 T 29-03-2018 CDC59_RS15705 9652ef963997e3716ea781d305e55b6f 301 SMART SM00062 40 272 8.6E-52 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CDC59_RS15705 9652ef963997e3716ea781d305e55b6f 301 SUPERFAMILY SSF53850 11 272 1.78E-56 T 29-03-2018 CDC59_RS15705 9652ef963997e3716ea781d305e55b6f 301 Gene3D G3DSA:3.40.190.10 35 169 4.9E-23 T 29-03-2018 CDC59_RS15705 9652ef963997e3716ea781d305e55b6f 301 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 42 270 1.8E-43 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CDC59_RS01820 4e1b909732af41571740d09f6a896b95 111 Pfam PF07363 Protein of unknown function (DUF1484) 5 111 8.7E-40 T 29-03-2018 IPR009957 Protein of unknown function DUF1484 CDC59_RS11175 298d4ed8f3915d9d5605143b62e21572 317 SUPERFAMILY SSF161098 108 301 1.96E-28 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS11175 298d4ed8f3915d9d5605143b62e21572 317 Gene3D G3DSA:1.10.3720.10 42 317 3.4E-43 T 29-03-2018 CDC59_RS11175 298d4ed8f3915d9d5605143b62e21572 317 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 132 315 6.2E-33 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS11175 298d4ed8f3915d9d5605143b62e21572 317 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 29 75 1.1E-9 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CDC59_RS07490 c925c827aa6f13250c7fee22e00ce292 364 SUPERFAMILY SSF56935 22 364 1.26E-77 T 29-03-2018 CDC59_RS07490 c925c827aa6f13250c7fee22e00ce292 364 Gene3D G3DSA:2.40.160.10 9 364 1.1E-64 T 29-03-2018 CDC59_RS07490 c925c827aa6f13250c7fee22e00ce292 364 Pfam PF13609 Gram-negative porin 7 332 7.1E-47 T 29-03-2018 CDC59_RS15070 b4b2d93c4b10b47ef1238f10e82e8336 195 Pfam PF01381 Helix-turn-helix 11 63 4.7E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDC59_RS15070 b4b2d93c4b10b47ef1238f10e82e8336 195 SUPERFAMILY SSF51182 51 182 2.97E-19 T 29-03-2018 IPR011051 RmlC-like cupin domain CDC59_RS15070 b4b2d93c4b10b47ef1238f10e82e8336 195 Gene3D G3DSA:2.60.120.10 67 192 2.4E-14 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CDC59_RS15070 b4b2d93c4b10b47ef1238f10e82e8336 195 SUPERFAMILY SSF47413 2 70 1.27E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDC59_RS15070 b4b2d93c4b10b47ef1238f10e82e8336 195 SMART SM00530 10 65 3.1E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDC59_RS15070 b4b2d93c4b10b47ef1238f10e82e8336 195 Gene3D G3DSA:1.10.260.40 1 66 8.1E-20 T 29-03-2018 CDC59_RS09480 0b65ff4b7413dae59895b1e1b91b3c16 413 SMART SM00327 220 377 0.0026 T 29-03-2018 IPR002035 von Willebrand factor, type A CDC59_RS09480 0b65ff4b7413dae59895b1e1b91b3c16 413 PIRSF PIRSF010256 1 394 1.1E-143 T 29-03-2018 IPR011195 Uncharacterised conserved protein UCP010256 CDC59_RS09480 0b65ff4b7413dae59895b1e1b91b3c16 413 Pfam PF05762 VWA domain containing CoxE-like protein 164 384 7.4E-80 T 29-03-2018 IPR008912 Uncharacterised protein family CoxE-like CDC59_RS09480 0b65ff4b7413dae59895b1e1b91b3c16 413 Gene3D G3DSA:3.40.50.410 187 392 9.4E-15 T 29-03-2018 IPR002035 von Willebrand factor, type A CDC59_RS09480 0b65ff4b7413dae59895b1e1b91b3c16 413 SUPERFAMILY SSF53300 222 349 8.26E-18 T 29-03-2018 IPR002035 von Willebrand factor, type A CDC59_RS12450 221c183748517676743741f358b8a04b 316 PIRSF PIRSF002936 11 316 1.8E-136 T 29-03-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 CDC59_RS12450 221c183748517676743741f358b8a04b 316 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 40 269 5.9E-46 T 29-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 CDC59_RS12450 221c183748517676743741f358b8a04b 316 Gene3D G3DSA:3.40.50.620 13 281 1.2E-36 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDC59_RS12450 221c183748517676743741f358b8a04b 316 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 20 316 8.7E-120 T 29-03-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 CDC59_RS12450 221c183748517676743741f358b8a04b 316 SUPERFAMILY SSF52402 16 224 2.21E-62 T 29-03-2018 CDC59_RS14905 44618eb06b6328d5c4ecdf1995fabaa9 129 Pfam PF03992 Antibiotic biosynthesis monooxygenase 28 104 9.9E-6 T 29-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CDC59_RS14905 44618eb06b6328d5c4ecdf1995fabaa9 129 Gene3D G3DSA:3.30.70.100 25 122 3.1E-23 T 29-03-2018 CDC59_RS14905 44618eb06b6328d5c4ecdf1995fabaa9 129 SUPERFAMILY SSF54909 19 127 4.47E-32 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CDC59_RS06490 695691e73b7a8bc93c3c2eb7abfb691c 343 SUPERFAMILY SSF53474 40 263 1.61E-31 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS06490 695691e73b7a8bc93c3c2eb7abfb691c 343 Gene3D G3DSA:3.40.50.1820 17 330 7.5E-31 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS06490 695691e73b7a8bc93c3c2eb7abfb691c 343 Pfam PF10503 Esterase PHB depolymerase 70 272 1.5E-68 T 29-03-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 CDC59_RS06490 695691e73b7a8bc93c3c2eb7abfb691c 343 TIGRFAM TIGR01840 esterase_phb: esterase, PHB depolymerase family 72 273 2.9E-36 T 29-03-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 CDC59_RS01040 bdc707e1b6ebb99e36e9bf9ea791637c 365 SUPERFAMILY SSF53822 31 351 9.76E-36 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CDC59_RS01040 bdc707e1b6ebb99e36e9bf9ea791637c 365 Pfam PF13458 Periplasmic binding protein 32 336 7.2E-29 T 29-03-2018 IPR028081 Leucine-binding protein domain CDC59_RS01040 bdc707e1b6ebb99e36e9bf9ea791637c 365 Gene3D G3DSA:3.40.50.2300 20 188 2.0E-13 T 29-03-2018 CDC59_RS01040 bdc707e1b6ebb99e36e9bf9ea791637c 365 Gene3D G3DSA:3.40.50.2300 200 356 1.2E-12 T 29-03-2018 CDC59_RS04185 0e0afacd3ce226f155b544a4e5d24eb5 212 Gene3D G3DSA:1.10.340.30 43 158 6.0E-22 T 29-03-2018 CDC59_RS04185 0e0afacd3ce226f155b544a4e5d24eb5 212 Gene3D G3DSA:1.10.1670.10 160 211 8.6E-16 T 29-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CDC59_RS04185 0e0afacd3ce226f155b544a4e5d24eb5 212 SUPERFAMILY SSF48150 42 209 5.93E-41 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CDC59_RS04185 0e0afacd3ce226f155b544a4e5d24eb5 212 SMART SM00478 55 211 1.0E-14 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CDC59_RS04185 0e0afacd3ce226f155b544a4e5d24eb5 212 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 51 195 1.0E-14 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CDC59_RS16765 91d449c006f71dfc4e9a61ed7c2f71a2 447 TIGRFAM TIGR01843 type_I_hlyD: type I secretion membrane fusion protein, HlyD family 57 447 3.3E-85 T 29-03-2018 IPR010129 Type I secretion membrane fusion protein, HlyD family GO:0015031|GO:0016021 CDC59_RS16765 91d449c006f71dfc4e9a61ed7c2f71a2 447 Gene3D G3DSA:2.40.50.100 90 335 8.8E-17 T 29-03-2018 CDC59_RS16765 91d449c006f71dfc4e9a61ed7c2f71a2 447 Pfam PF13533 Biotin-lipoyl like 107 137 3.4E-8 T 29-03-2018 CDC59_RS16765 91d449c006f71dfc4e9a61ed7c2f71a2 447 Pfam PF13437 HlyD family secretion protein 299 414 2.4E-17 T 29-03-2018 CDC59_RS16765 91d449c006f71dfc4e9a61ed7c2f71a2 447 ProSitePatterns PS00543 HlyD family secretion proteins signature. 411 433 - T 29-03-2018 IPR006144 Secretion protein HlyD, conserved site GO:0008565|GO:0009306|GO:0016020 CDC59_RS16765 91d449c006f71dfc4e9a61ed7c2f71a2 447 SUPERFAMILY SSF111369 102 160 4.71E-6 T 29-03-2018 CDC59_RS16765 91d449c006f71dfc4e9a61ed7c2f71a2 447 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 67 90 6.1E-56 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CDC59_RS16765 91d449c006f71dfc4e9a61ed7c2f71a2 447 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 344 368 6.1E-56 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CDC59_RS16765 91d449c006f71dfc4e9a61ed7c2f71a2 447 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 368 391 6.1E-56 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CDC59_RS16765 91d449c006f71dfc4e9a61ed7c2f71a2 447 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 426 446 6.1E-56 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CDC59_RS16765 91d449c006f71dfc4e9a61ed7c2f71a2 447 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 109 129 6.1E-56 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CDC59_RS16765 91d449c006f71dfc4e9a61ed7c2f71a2 447 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 311 332 6.1E-56 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CDC59_RS16765 91d449c006f71dfc4e9a61ed7c2f71a2 447 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 411 426 6.1E-56 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CDC59_RS20960 192030d297894cf7faf452c8262214c7 524 Gene3D G3DSA:1.10.287.950 315 517 9.8E-49 T 29-03-2018 CDC59_RS20960 192030d297894cf7faf452c8262214c7 524 SUPERFAMILY SSF58104 235 514 1.96E-71 T 29-03-2018 CDC59_RS20960 192030d297894cf7faf452c8262214c7 524 Pfam PF12729 Four helix bundle sensory module for signal transduction 7 186 3.7E-26 T 29-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain CDC59_RS20960 192030d297894cf7faf452c8262214c7 524 SMART SM00304 213 265 2.9E-5 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CDC59_RS20960 192030d297894cf7faf452c8262214c7 524 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 326 481 1.6E-49 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CDC59_RS20960 192030d297894cf7faf452c8262214c7 524 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 287 316 5.4E-55 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS20960 192030d297894cf7faf452c8262214c7 524 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 364 391 5.4E-55 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS20960 192030d297894cf7faf452c8262214c7 524 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 441 470 5.4E-55 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS20960 192030d297894cf7faf452c8262214c7 524 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 393 422 5.4E-55 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS20960 192030d297894cf7faf452c8262214c7 524 SMART SM00283 266 513 1.4E-84 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CDC59_RS20960 192030d297894cf7faf452c8262214c7 524 Gene3D G3DSA:1.20.120.30 25 187 4.4E-24 T 29-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain CDC59_RS17755 15f3a2da8c967adfbd0e7a058a705b7a 302 Gene3D G3DSA:3.20.20.140 18 302 4.3E-40 T 29-03-2018 CDC59_RS17755 15f3a2da8c967adfbd0e7a058a705b7a 302 SUPERFAMILY SSF51556 38 301 7.88E-76 T 29-03-2018 IPR032466 Metal-dependent hydrolase CDC59_RS17755 15f3a2da8c967adfbd0e7a058a705b7a 302 Pfam PF04909 Amidohydrolase 38 301 5.0E-41 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CDC59_RS04725 a262349369508acf651612025612f3ea 134 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 8 122 4.2E-32 T 29-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 CDC59_RS04725 a262349369508acf651612025612f3ea 134 TIGRFAM TIGR02799 thio_ybgC: tol-pal system-associated acyl-CoA thioesterase 4 127 1.4E-48 T 29-03-2018 IPR014166 Tol-Pal system-associated acyl-CoA thioesterase GO:0016790 CDC59_RS04725 a262349369508acf651612025612f3ea 134 Gene3D G3DSA:3.10.129.10 1 134 1.3E-37 T 29-03-2018 CDC59_RS04725 a262349369508acf651612025612f3ea 134 PIRSF PIRSF003230 1 134 5.5E-44 T 29-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 CDC59_RS04725 a262349369508acf651612025612f3ea 134 SUPERFAMILY SSF54637 2 131 3.58E-42 T 29-03-2018 IPR029069 HotDog domain CDC59_RS04725 a262349369508acf651612025612f3ea 134 Pfam PF03061 Thioesterase superfamily 18 102 3.0E-18 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CDC59_RS03460 0473c6fe87dbeb2a3120cbcd0493255a 693 Pfam PF00773 RNB domain 480 523 5.0E-10 T 29-03-2018 CDC59_RS03460 0473c6fe87dbeb2a3120cbcd0493255a 693 Pfam PF00773 RNB domain 241 476 2.5E-32 T 29-03-2018 CDC59_RS03460 0473c6fe87dbeb2a3120cbcd0493255a 693 SUPERFAMILY SSF50249 205 574 4.28E-70 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CDC59_RS03460 0473c6fe87dbeb2a3120cbcd0493255a 693 SMART SM00955 235 525 3.8E-64 T 29-03-2018 CDC59_RS20435 7dc541bfdb0a06a5e0386950cc8d0dd3 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.0E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS20435 7dc541bfdb0a06a5e0386950cc8d0dd3 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.0E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS20435 7dc541bfdb0a06a5e0386950cc8d0dd3 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.0E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS20435 7dc541bfdb0a06a5e0386950cc8d0dd3 313 SUPERFAMILY SSF46785 1 87 1.6E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS20435 7dc541bfdb0a06a5e0386950cc8d0dd3 313 SUPERFAMILY SSF53850 87 297 1.71E-31 T 29-03-2018 CDC59_RS20435 7dc541bfdb0a06a5e0386950cc8d0dd3 313 Pfam PF03466 LysR substrate binding domain 87 293 4.6E-32 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS20435 7dc541bfdb0a06a5e0386950cc8d0dd3 313 Gene3D G3DSA:1.10.10.10 1 83 1.6E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS20435 7dc541bfdb0a06a5e0386950cc8d0dd3 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 8.0E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS20435 7dc541bfdb0a06a5e0386950cc8d0dd3 313 Gene3D G3DSA:3.40.190.10 179 264 3.4E-13 T 29-03-2018 CDC59_RS20435 7dc541bfdb0a06a5e0386950cc8d0dd3 313 Gene3D G3DSA:3.40.190.10 88 178 1.8E-14 T 29-03-2018 CDC59_RS02405 3a5645b9de2a7d36276e11ce86e3516a 395 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 156 393 1.1E-74 T 29-03-2018 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 CDC59_RS02405 3a5645b9de2a7d36276e11ce86e3516a 395 Pfam PF01578 Cytochrome C assembly protein 186 390 2.5E-49 T 29-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 CDC59_RS20460 786700a3e9e617f38219d575fe745874 139 Gene3D G3DSA:2.40.50.100 41 138 4.2E-5 T 29-03-2018 CDC59_RS20460 786700a3e9e617f38219d575fe745874 139 SUPERFAMILY SSF51230 63 136 1.17E-7 T 29-03-2018 IPR011053 Single hybrid motif CDC59_RS13850 f23f9192ed6783afb23cea83b92d2f21 298 Gene3D G3DSA:3.40.190.10 166 298 4.7E-16 T 29-03-2018 CDC59_RS13850 f23f9192ed6783afb23cea83b92d2f21 298 SUPERFAMILY SSF53850 6 269 5.93E-60 T 29-03-2018 CDC59_RS13850 f23f9192ed6783afb23cea83b92d2f21 298 SMART SM00062 37 269 1.2E-55 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CDC59_RS13850 f23f9192ed6783afb23cea83b92d2f21 298 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 38 267 1.3E-46 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CDC59_RS13850 f23f9192ed6783afb23cea83b92d2f21 298 Gene3D G3DSA:3.40.190.10 3 165 2.4E-31 T 29-03-2018 CDC59_RS20850 5d703231845ed78d553ce2cfcd3556f3 145 SUPERFAMILY SSF52788 1 141 1.7E-41 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CDC59_RS20850 5d703231845ed78d553ce2cfcd3556f3 145 SMART SM00226 3 140 8.3E-65 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CDC59_RS20850 5d703231845ed78d553ce2cfcd3556f3 145 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 41 57 2.2E-17 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CDC59_RS20850 5d703231845ed78d553ce2cfcd3556f3 145 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 5 22 2.2E-17 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CDC59_RS20850 5d703231845ed78d553ce2cfcd3556f3 145 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 75 90 2.2E-17 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CDC59_RS20850 5d703231845ed78d553ce2cfcd3556f3 145 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 112 127 2.2E-17 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CDC59_RS20850 5d703231845ed78d553ce2cfcd3556f3 145 Gene3D G3DSA:3.40.50.2300 2 144 1.5E-43 T 29-03-2018 CDC59_RS20850 5d703231845ed78d553ce2cfcd3556f3 145 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 5 138 3.3E-43 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CDC59_RS03720 e5c68db2022a7edd1a928f9ed5c34b58 627 Pfam PF07549 SecD/SecF GG Motif 132 149 2.4E-4 T 29-03-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site CDC59_RS03720 e5c68db2022a7edd1a928f9ed5c34b58 627 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 356 589 8.3E-70 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CDC59_RS03720 e5c68db2022a7edd1a928f9ed5c34b58 627 Pfam PF13721 SecD export protein N-terminal TM region 1 112 1.3E-35 T 29-03-2018 IPR027398 SecD export protein N-terminal TM domain CDC59_RS03720 e5c68db2022a7edd1a928f9ed5c34b58 627 SUPERFAMILY SSF82866 406 605 6.41E-36 T 29-03-2018 CDC59_RS03720 e5c68db2022a7edd1a928f9ed5c34b58 627 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 132 596 3.3E-135 T 29-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 CDC59_RS03720 e5c68db2022a7edd1a928f9ed5c34b58 627 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 2 610 47.761 T 29-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 CDC59_RS03720 e5c68db2022a7edd1a928f9ed5c34b58 627 Gene3D G3DSA:1.20.1640.10 391 602 4.5E-28 T 29-03-2018 CDC59_RS03720 e5c68db2022a7edd1a928f9ed5c34b58 627 Pfam PF02355 Protein export membrane protein 428 599 2.2E-19 T 29-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial CDC59_RS03485 96c1484402ef992aa92b6547c2d94c8f 320 Gene3D G3DSA:1.20.58.340 137 251 2.1E-12 T 29-03-2018 CDC59_RS03485 96c1484402ef992aa92b6547c2d94c8f 320 SUPERFAMILY SSF144083 254 317 2.62E-20 T 29-03-2018 CDC59_RS03485 96c1484402ef992aa92b6547c2d94c8f 320 Gene3D G3DSA:1.20.58.340 252 319 3.0E-19 T 29-03-2018 CDC59_RS03485 96c1484402ef992aa92b6547c2d94c8f 320 Gene3D G3DSA:3.30.460.20 1 133 5.6E-17 T 29-03-2018 CDC59_RS03485 96c1484402ef992aa92b6547c2d94c8f 320 Pfam PF01544 CorA-like Mg2+ transporter protein 29 315 1.8E-59 T 29-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 CDC59_RS03485 96c1484402ef992aa92b6547c2d94c8f 320 SUPERFAMILY SSF143865 1 258 1.29E-37 T 29-03-2018 CDC59_RS03485 96c1484402ef992aa92b6547c2d94c8f 320 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 2 319 7.3E-76 T 29-03-2018 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 CDC59_RS13510 9023c2815257d360e6597b47d7847439 348 SUPERFAMILY SSF56112 16 348 5.54E-81 T 29-03-2018 IPR011009 Protein kinase-like domain CDC59_RS13510 9023c2815257d360e6597b47d7847439 348 Gene3D G3DSA:3.30.200.20 15 117 9.6E-18 T 29-03-2018 CDC59_RS13510 9023c2815257d360e6597b47d7847439 348 Gene3D G3DSA:3.90.1200.10 124 345 1.8E-19 T 29-03-2018 CDC59_RS13510 9023c2815257d360e6597b47d7847439 348 Pfam PF01636 Phosphotransferase enzyme family 46 287 2.6E-38 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase CDC59_RS13510 9023c2815257d360e6597b47d7847439 348 Hamap MF_01497 Stress response kinase A [srkA]. 14 343 47.244 T 29-03-2018 IPR032882 SrkA/RdoA protein kinase GO:0004674|GO:0006468 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CDC59_RS10920 45fe404838d25b62bf2a36638cd1da47 321 SUPERFAMILY SSF161098 32 305 2.99E-31 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS10920 45fe404838d25b62bf2a36638cd1da47 321 Gene3D G3DSA:1.10.3720.10 23 320 6.7E-28 T 29-03-2018 CDC59_RS10920 45fe404838d25b62bf2a36638cd1da47 321 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 310 2.5E-16 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS10920 45fe404838d25b62bf2a36638cd1da47 321 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 20 313 7.2E-91 T 29-03-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 CDC59_RS17155 941bef3b247e5bdae4d7e09fc16e3f5b 147 SMART SM00347 28 126 6.1E-15 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS17155 941bef3b247e5bdae4d7e09fc16e3f5b 147 Gene3D G3DSA:1.10.10.10 1 147 8.3E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS17155 941bef3b247e5bdae4d7e09fc16e3f5b 147 SUPERFAMILY SSF46785 3 142 8.65E-33 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS17155 941bef3b247e5bdae4d7e09fc16e3f5b 147 Pfam PF01047 MarR family 35 93 3.9E-16 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS05330 c0e707e2dd59ae7be1f9bd781cef3706 117 Pfam PF13876 Phage protein (N4 Gp49/phage Sf6 gene 66) family 18 113 3.1E-37 T 29-03-2018 IPR025915 Phage protein (N4 Gp49/phage Sf6 gene 66) family CDC59_RS16450 009e6d9a472550bf7230f292a311fed6 895 Pfam PF05593 RHS Repeat 289 325 2.8E-9 T 29-03-2018 IPR031325 RHS repeat CDC59_RS16450 009e6d9a472550bf7230f292a311fed6 895 Pfam PF05593 RHS Repeat 331 368 9.5E-8 T 29-03-2018 IPR031325 RHS repeat CDC59_RS16450 009e6d9a472550bf7230f292a311fed6 895 Pfam PF05593 RHS Repeat 667 690 1.2E-4 T 29-03-2018 IPR031325 RHS repeat CDC59_RS16450 009e6d9a472550bf7230f292a311fed6 895 Pfam PF05593 RHS Repeat 468 504 2.4E-5 T 29-03-2018 IPR031325 RHS repeat CDC59_RS16450 009e6d9a472550bf7230f292a311fed6 895 Pfam PF05593 RHS Repeat 630 666 2.8E-8 T 29-03-2018 IPR031325 RHS repeat CDC59_RS16450 009e6d9a472550bf7230f292a311fed6 895 Pfam PF05593 RHS Repeat 697 734 2.1E-7 T 29-03-2018 IPR031325 RHS repeat CDC59_RS16450 009e6d9a472550bf7230f292a311fed6 895 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 289 329 2.0E-6 T 29-03-2018 IPR006530 YD repeat CDC59_RS16450 009e6d9a472550bf7230f292a311fed6 895 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 630 663 5.7E-4 T 29-03-2018 IPR006530 YD repeat CDC59_RS16450 009e6d9a472550bf7230f292a311fed6 895 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 667 695 1.6E-4 T 29-03-2018 IPR006530 YD repeat CDC59_RS16450 009e6d9a472550bf7230f292a311fed6 895 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 332 371 1.2E-8 T 29-03-2018 IPR006530 YD repeat CDC59_RS16450 009e6d9a472550bf7230f292a311fed6 895 Pfam PF00754 F5/8 type C domain 776 891 2.0E-12 T 29-03-2018 IPR000421 Coagulation factor 5/8 C-terminal domain CDC59_RS16450 009e6d9a472550bf7230f292a311fed6 895 Gene3D G3DSA:2.60.120.260 773 895 3.9E-17 T 29-03-2018 IPR008979 Galactose-binding domain-like CDC59_RS16450 009e6d9a472550bf7230f292a311fed6 895 SUPERFAMILY SSF49785 776 894 6.03E-18 T 29-03-2018 IPR008979 Galactose-binding domain-like CDC59_RS08095 f90868e0193c785ce1a641c0ccb0ef7f 368 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 5 340 1.9E-88 T 29-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CDC59_RS08095 f90868e0193c785ce1a641c0ccb0ef7f 368 Gene3D G3DSA:3.20.20.70 1 368 1.5E-126 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS08095 f90868e0193c785ce1a641c0ccb0ef7f 368 SUPERFAMILY SSF51395 3 366 9.95E-124 T 29-03-2018 CDC59_RS21315 1d5ee4908319e8cdfae2551e3deb8b36 305 PIRSF PIRSF000126 1 264 5.8E-70 T 29-03-2018 CDC59_RS21315 1d5ee4908319e8cdfae2551e3deb8b36 305 Pfam PF00106 short chain dehydrogenase 10 200 1.6E-43 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS21315 1d5ee4908319e8cdfae2551e3deb8b36 305 Gene3D G3DSA:3.40.50.720 1 266 4.1E-57 T 29-03-2018 CDC59_RS21315 1d5ee4908319e8cdfae2551e3deb8b36 305 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 6.1E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS21315 1d5ee4908319e8cdfae2551e3deb8b36 305 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 6.1E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS21315 1d5ee4908319e8cdfae2551e3deb8b36 305 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 6.1E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS21315 1d5ee4908319e8cdfae2551e3deb8b36 305 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 2.3E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS21315 1d5ee4908319e8cdfae2551e3deb8b36 305 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 2.3E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS21315 1d5ee4908319e8cdfae2551e3deb8b36 305 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 2.3E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS21315 1d5ee4908319e8cdfae2551e3deb8b36 305 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 2.3E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS21315 1d5ee4908319e8cdfae2551e3deb8b36 305 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 2.3E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS21315 1d5ee4908319e8cdfae2551e3deb8b36 305 SUPERFAMILY SSF51735 3 252 1.98E-60 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS17105 3838ba6a4d35d67b81b0415ba970e4bc 153 TIGRFAM TIGR02480 fliN: flagellar motor switch protein FliN 69 144 4.2E-33 T 29-03-2018 IPR012826 Flagellar motor switch FliN GO:0006935|GO:0009288|GO:0016020|GO:0071973 CDC59_RS17105 3838ba6a4d35d67b81b0415ba970e4bc 153 PRINTS PR00956 Flagellar motor switch protein FliN signature 72 88 3.9E-29 T 29-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CDC59_RS17105 3838ba6a4d35d67b81b0415ba970e4bc 153 PRINTS PR00956 Flagellar motor switch protein FliN signature 118 133 3.9E-29 T 29-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CDC59_RS17105 3838ba6a4d35d67b81b0415ba970e4bc 153 PRINTS PR00956 Flagellar motor switch protein FliN signature 105 118 3.9E-29 T 29-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CDC59_RS17105 3838ba6a4d35d67b81b0415ba970e4bc 153 PRINTS PR00956 Flagellar motor switch protein FliN signature 89 105 3.9E-29 T 29-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CDC59_RS17105 3838ba6a4d35d67b81b0415ba970e4bc 153 Gene3D G3DSA:2.30.330.10 58 153 3.1E-31 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) CDC59_RS17105 3838ba6a4d35d67b81b0415ba970e4bc 153 SUPERFAMILY SSF101801 69 151 4.84E-26 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) CDC59_RS17105 3838ba6a4d35d67b81b0415ba970e4bc 153 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 72 142 5.9E-25 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) CDC59_RS16170 b7790f6dc736fa5d6e18395ac7bd197a 220 Pfam PF09849 Uncharacterized protein conserved in bacteria (DUF2076) 1 201 1.5E-41 T 29-03-2018 IPR018648 Protein of unknown function DUF2076 CDC59_RS10520 ecdd9cb92a4c9545754d68baa18521c4 706 SUPERFAMILY SSF55486 14 698 1.71E-192 T 29-03-2018 CDC59_RS10520 ecdd9cb92a4c9545754d68baa18521c4 706 Pfam PF01432 Peptidase family M3 235 696 3.3E-143 T 29-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 CDC59_RS10520 ecdd9cb92a4c9545754d68baa18521c4 706 Gene3D G3DSA:1.20.1050.40 17 149 6.9E-32 T 29-03-2018 IPR024080 Neurolysin/Thimet oligopeptidase, N-terminal CDC59_RS10520 ecdd9cb92a4c9545754d68baa18521c4 706 Gene3D G3DSA:1.10.1370.10 151 451 1.1E-54 T 29-03-2018 CDC59_RS10520 ecdd9cb92a4c9545754d68baa18521c4 706 Gene3D G3DSA:1.10.1370.10 473 705 1.8E-63 T 29-03-2018 CDC59_RS21445 958cfb5058a6720a628ed125c5e8e65c 109 Pfam PF12266 Protein of unknown function (DUF3613) 30 87 3.7E-8 T 29-03-2018 IPR022053 Protein of unknown function DUF3613 CDC59_RS04845 b73cc976527b343955198c981ecf4c14 460 Pfam PF00860 Permease family 39 420 6.3E-69 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CDC59_RS18570 31ee67ea8d262dfd7b9e34a2edff3e9e 150 SUPERFAMILY SSF160631 34 133 3.92E-7 T 29-03-2018 CDC59_RS18570 31ee67ea8d262dfd7b9e34a2edff3e9e 150 Gene3D G3DSA:3.40.1580.10 19 136 6.8E-7 T 29-03-2018 CDC59_RS07710 950eee0f3c415607d58d27d84eb36095 175 Gene3D G3DSA:2.160.10.10 1 175 1.7E-41 T 29-03-2018 CDC59_RS07710 950eee0f3c415607d58d27d84eb36095 175 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 88 122 2.2E-7 T 29-03-2018 IPR001451 Hexapeptide repeat CDC59_RS07710 950eee0f3c415607d58d27d84eb36095 175 SUPERFAMILY SSF51161 4 170 2.22E-46 T 29-03-2018 IPR011004 Trimeric LpxA-like CDC59_RS00800 110d7c0c0614fd086f3842e032d9ae8a 225 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 35 221 5.7E-48 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CDC59_RS00800 110d7c0c0614fd086f3842e032d9ae8a 225 Gene3D G3DSA:3.40.50.150 3 224 1.1E-33 T 29-03-2018 CDC59_RS00800 110d7c0c0614fd086f3842e032d9ae8a 225 SUPERFAMILY SSF53335 18 222 7.56E-38 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS00800 110d7c0c0614fd086f3842e032d9ae8a 225 Pfam PF02527 rRNA small subunit methyltransferase G 31 218 1.3E-48 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CDC59_RS00800 110d7c0c0614fd086f3842e032d9ae8a 225 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 23 220 26.317 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CDC59_RS00800 110d7c0c0614fd086f3842e032d9ae8a 225 PIRSF PIRSF003078 8 224 5.5E-52 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CDC59_RS19360 f6f31d02cb416a1179ecf4d323f80ade 428 SUPERFAMILY SSF51419 45 280 6.87E-30 T 29-03-2018 IPR029066 PLP-binding barrel CDC59_RS19360 f6f31d02cb416a1179ecf4d323f80ade 428 SUPERFAMILY SSF50621 251 415 2.05E-18 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CDC59_RS19360 f6f31d02cb416a1179ecf4d323f80ade 428 Gene3D G3DSA:2.40.37.10 273 415 8.4E-15 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CDC59_RS19360 f6f31d02cb416a1179ecf4d323f80ade 428 Gene3D G3DSA:3.20.20.10 45 272 1.3E-18 T 29-03-2018 IPR029066 PLP-binding barrel CDC59_RS03170 026918a8b74fa591601037345ae0c1a5 169 Pfam PF05258 Protein of unknown function (DUF721) 18 109 8.0E-6 T 29-03-2018 IPR007922 Protein of unknown function DUF721/UPF0232 CDC59_RS14700 fed0e0e92dc358bdb947cd20e19dce3a 638 Pfam PF03421 YopJ Serine/Threonine acetyltransferase 88 275 1.0E-16 T 29-03-2018 IPR005083 Serine/Threonine acetyltransferase, YopJ CDC59_RS14700 fed0e0e92dc358bdb947cd20e19dce3a 638 Pfam PF03421 YopJ Serine/Threonine acetyltransferase 403 571 1.4E-6 T 29-03-2018 IPR005083 Serine/Threonine acetyltransferase, YopJ CDC59_RS07620 6afdb2437ceaf72ca6c78d2d4d4753ad 565 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 23 563 1.6E-145 T 29-03-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 CDC59_RS07620 6afdb2437ceaf72ca6c78d2d4d4753ad 565 Gene3D G3DSA:3.90.1640.10 53 254 3.9E-20 T 29-03-2018 CDC59_RS07620 6afdb2437ceaf72ca6c78d2d4d4753ad 565 Pfam PF01368 DHH family 75 176 2.8E-8 T 29-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CDC59_RS07620 6afdb2437ceaf72ca6c78d2d4d4753ad 565 SUPERFAMILY SSF64182 48 462 1.83E-117 T 29-03-2018 CDC59_RS07620 6afdb2437ceaf72ca6c78d2d4d4753ad 565 Pfam PF02272 DHHA1 domain 319 449 8.6E-26 T 29-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CDC59_RS03995 6feb8b7a64fb4b323ee171bf357a58cb 1425 Pfam PF13502 AsmA-like C-terminal region 1161 1412 1.4E-56 T 29-03-2018 IPR032712 AsmA-like, C-terminal CDC59_RS03995 6feb8b7a64fb4b323ee171bf357a58cb 1425 Pfam PF13116 Protein of unknown function 629 921 4.5E-57 T 29-03-2018 IPR025263 Domain of unknown function DUF3971 CDC59_RS03995 6feb8b7a64fb4b323ee171bf357a58cb 1425 TIGRFAM TIGR02099 TIGR02099: TIGR02099 family protein 60 1417 1.1E-201 T 29-03-2018 IPR011836 Conserved hypothetical protein CHP02099 CDC59_RS22180 7a9a20f49ff3226dd2b94da115d69485 476 Pfam PF00474 Sodium:solute symporter family 38 415 1.2E-22 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CDC59_RS21160 35bde5094ec6064e5c1a4e8d6d0f018e 1031 SUPERFAMILY SSF82693 137 180 3.31E-14 T 29-03-2018 CDC59_RS21160 35bde5094ec6064e5c1a4e8d6d0f018e 1031 SUPERFAMILY SSF82693 266 323 3.31E-14 T 29-03-2018 CDC59_RS21160 35bde5094ec6064e5c1a4e8d6d0f018e 1031 SUPERFAMILY SSF82866 289 487 2.75E-37 T 29-03-2018 CDC59_RS21160 35bde5094ec6064e5c1a4e8d6d0f018e 1031 Gene3D G3DSA:3.30.70.1430 42 141 4.9E-19 T 29-03-2018 CDC59_RS21160 35bde5094ec6064e5c1a4e8d6d0f018e 1031 SUPERFAMILY SSF82714 706 791 1.23E-16 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS21160 35bde5094ec6064e5c1a4e8d6d0f018e 1031 Gene3D G3DSA:1.20.1640.10 808 1014 5.3E-36 T 29-03-2018 CDC59_RS21160 35bde5094ec6064e5c1a4e8d6d0f018e 1031 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 6 1015 1.5E-280 T 29-03-2018 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 CDC59_RS21160 35bde5094ec6064e5c1a4e8d6d0f018e 1031 Gene3D G3DSA:1.20.1640.10 282 496 4.3E-39 T 29-03-2018 CDC59_RS21160 35bde5094ec6064e5c1a4e8d6d0f018e 1031 Gene3D G3DSA:3.30.2090.10 179 266 2.0E-16 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS21160 35bde5094ec6064e5c1a4e8d6d0f018e 1031 SUPERFAMILY SSF82866 789 1014 4.32E-48 T 29-03-2018 CDC59_RS21160 35bde5094ec6064e5c1a4e8d6d0f018e 1031 PRINTS PR00702 Acriflavin resistance protein family signature 437 460 7.9E-29 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS21160 35bde5094ec6064e5c1a4e8d6d0f018e 1031 PRINTS PR00702 Acriflavin resistance protein family signature 462 485 7.9E-29 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS21160 35bde5094ec6064e5c1a4e8d6d0f018e 1031 PRINTS PR00702 Acriflavin resistance protein family signature 383 407 7.9E-29 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS21160 35bde5094ec6064e5c1a4e8d6d0f018e 1031 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 7.9E-29 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS21160 35bde5094ec6064e5c1a4e8d6d0f018e 1031 PRINTS PR00702 Acriflavin resistance protein family signature 12 36 7.9E-29 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS21160 35bde5094ec6064e5c1a4e8d6d0f018e 1031 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 7.9E-29 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS21160 35bde5094ec6064e5c1a4e8d6d0f018e 1031 SUPERFAMILY SSF82714 182 263 4.58E-16 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS21160 35bde5094ec6064e5c1a4e8d6d0f018e 1031 SUPERFAMILY SSF82693 552 645 2.59E-5 T 29-03-2018 CDC59_RS21160 35bde5094ec6064e5c1a4e8d6d0f018e 1031 Gene3D G3DSA:3.30.70.1430 550 651 9.6E-11 T 29-03-2018 CDC59_RS21160 35bde5094ec6064e5c1a4e8d6d0f018e 1031 SUPERFAMILY SSF82693 44 126 2.96E-17 T 29-03-2018 CDC59_RS21160 35bde5094ec6064e5c1a4e8d6d0f018e 1031 Pfam PF00873 AcrB/AcrD/AcrF family 8 1009 1.6E-258 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS21160 35bde5094ec6064e5c1a4e8d6d0f018e 1031 Gene3D G3DSA:3.30.2090.10 705 793 8.3E-20 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS03540 5f7dd7d85bf611b5f1577bab8499b454 141 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 16 130 5.9E-14 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CDC59_RS03540 5f7dd7d85bf611b5f1577bab8499b454 141 SUPERFAMILY SSF54593 10 135 4.3E-29 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CDC59_RS03540 5f7dd7d85bf611b5f1577bab8499b454 141 Gene3D G3DSA:3.10.180.10 8 140 4.3E-29 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CDC59_RS08480 2ee67253bda2d061bd06dc992b902785 365 Pfam PF03969 AFG1-like ATPase 2 354 4.4E-127 T 29-03-2018 IPR005654 ATPase, AFG1-like GO:0005524 CDC59_RS08480 2ee67253bda2d061bd06dc992b902785 365 SUPERFAMILY SSF52540 45 210 1.17E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS08480 2ee67253bda2d061bd06dc992b902785 365 Gene3D G3DSA:3.40.50.300 18 276 8.6E-15 T 29-03-2018 CDC59_RS02930 e7a7577ce9a07065c67cc9625ce52084 242 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 12 222 2.1E-91 T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CDC59_RS02930 e7a7577ce9a07065c67cc9625ce52084 242 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 39 53 - T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CDC59_RS02930 e7a7577ce9a07065c67cc9625ce52084 242 PIRSF PIRSF001461 7 240 1.9E-99 T 29-03-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CDC59_RS02930 e7a7577ce9a07065c67cc9625ce52084 242 SUPERFAMILY SSF51366 10 222 3.36E-68 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CDC59_RS02930 e7a7577ce9a07065c67cc9625ce52084 242 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 146 168 - T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CDC59_RS02930 e7a7577ce9a07065c67cc9625ce52084 242 Pfam PF00834 Ribulose-phosphate 3 epimerase family 12 217 1.4E-87 T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CDC59_RS02930 e7a7577ce9a07065c67cc9625ce52084 242 Gene3D G3DSA:3.20.20.70 2 238 3.7E-83 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS16005 2ba34fe1cc8ef4d7c3edf3a45470a860 265 Pfam PF10086 Putative membrane peptidase family (DUF2324) 19 238 3.3E-76 T 29-03-2018 IPR011397 Uncharacterised conserved protein UCP033101 CDC59_RS16005 2ba34fe1cc8ef4d7c3edf3a45470a860 265 PIRSF PIRSF033101 2 263 5.2E-106 T 29-03-2018 IPR011397 Uncharacterised conserved protein UCP033101 CDC59_RS12100 12d0e763d3dc9d4c20b62803874f238b 407 SUPERFAMILY SSF55729 211 383 6.0E-35 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDC59_RS12100 12d0e763d3dc9d4c20b62803874f238b 407 Pfam PF04339 Peptidogalycan biosysnthesis/recognition 27 404 1.4E-148 T 29-03-2018 IPR007434 Peptidogalycan biosysnthesis/recognition CDC59_RS12100 12d0e763d3dc9d4c20b62803874f238b 407 Gene3D G3DSA:3.40.630.30 210 364 3.2E-34 T 29-03-2018 CDC59_RS12100 12d0e763d3dc9d4c20b62803874f238b 407 Gene3D G3DSA:3.40.630.30 25 209 2.2E-14 T 29-03-2018 CDC59_RS10690 646c2ce9cbc742ca490828c79188e3bf 344 SUPERFAMILY SSF46589 15 100 2.14E-19 T 29-03-2018 IPR010978 tRNA-binding arm GO:0000166 CDC59_RS10690 646c2ce9cbc742ca490828c79188e3bf 344 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 39 343 5.8E-97 T 29-03-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CDC59_RS10690 646c2ce9cbc742ca490828c79188e3bf 344 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 20 88 5.3E-20 T 29-03-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CDC59_RS10690 646c2ce9cbc742ca490828c79188e3bf 344 Gene3D G3DSA:3.30.930.10 8 344 6.0E-85 T 29-03-2018 CDC59_RS10690 646c2ce9cbc742ca490828c79188e3bf 344 SUPERFAMILY SSF55681 93 343 2.9E-74 T 29-03-2018 CDC59_RS10690 646c2ce9cbc742ca490828c79188e3bf 344 Pfam PF01409 tRNA synthetases class II core domain (F) 93 343 5.0E-94 T 29-03-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 CDC59_RS10690 646c2ce9cbc742ca490828c79188e3bf 344 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 9 343 45.8 T 29-03-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 CDC59_RS10020 ccafd8fde29dedaa598f37d62777b915 94 PIRSF PIRSF003113 1 94 2.8E-28 T 29-03-2018 IPR002634 BolA protein CDC59_RS10020 ccafd8fde29dedaa598f37d62777b915 94 Pfam PF01722 BolA-like protein 16 92 1.2E-29 T 29-03-2018 IPR002634 BolA protein CDC59_RS10020 ccafd8fde29dedaa598f37d62777b915 94 Gene3D G3DSA:3.30.300.90 3 94 2.7E-27 T 29-03-2018 CDC59_RS10020 ccafd8fde29dedaa598f37d62777b915 94 SUPERFAMILY SSF82657 6 92 5.49E-28 T 29-03-2018 IPR002634 BolA protein CDC59_RS13385 143ce65ece77160ab6c664c8f0cb0237 146 Gene3D G3DSA:3.10.450.50 8 138 7.0E-17 T 29-03-2018 CDC59_RS13385 143ce65ece77160ab6c664c8f0cb0237 146 SUPERFAMILY SSF54427 8 130 3.6E-21 T 29-03-2018 IPR032710 NTF2-like domain CDC59_RS13385 143ce65ece77160ab6c664c8f0cb0237 146 Pfam PF13474 SnoaL-like domain 12 130 1.5E-23 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CDC59_RS02825 525ba437a93e5c0f0616b555a2e13098 360 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 228 244 - T 29-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CDC59_RS02825 525ba437a93e5c0f0616b555a2e13098 360 SUPERFAMILY SSF75620 12 353 3.01E-135 T 29-03-2018 CDC59_RS02825 525ba437a93e5c0f0616b555a2e13098 360 Gene3D G3DSA:3.30.160.20 209 292 2.0E-32 T 29-03-2018 CDC59_RS02825 525ba437a93e5c0f0616b555a2e13098 360 Pfam PF03462 PCRF domain 13 203 2.6E-71 T 29-03-2018 IPR005139 Peptide chain release factor GO:0006415 CDC59_RS02825 525ba437a93e5c0f0616b555a2e13098 360 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 1 356 1.2E-162 T 29-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 CDC59_RS02825 525ba437a93e5c0f0616b555a2e13098 360 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 5 357 40.406 T 29-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 CDC59_RS02825 525ba437a93e5c0f0616b555a2e13098 360 Pfam PF00472 RF-1 domain 214 321 3.0E-42 T 29-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CDC59_RS02825 525ba437a93e5c0f0616b555a2e13098 360 Gene3D G3DSA:1.20.58.410 4 96 3.7E-15 T 29-03-2018 CDC59_RS02825 525ba437a93e5c0f0616b555a2e13098 360 SMART SM00937 63 178 3.1E-65 T 29-03-2018 IPR005139 Peptide chain release factor GO:0006415 CDC59_RS21450 5423e0caa5634eb975eeae4ad2dd4691 307 Gene3D G3DSA:1.25.40.10 41 146 3.0E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS21450 5423e0caa5634eb975eeae4ad2dd4691 307 SUPERFAMILY SSF48452 68 227 6.78E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS21450 5423e0caa5634eb975eeae4ad2dd4691 307 PIRSF PIRSF029658 4 301 2.4E-94 T 29-03-2018 IPR016931 Uncharacterised conserved protein UCP029658, TPR CDC59_RS21450 5423e0caa5634eb975eeae4ad2dd4691 307 Gene3D G3DSA:1.25.40.10 147 179 2.0E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS21450 5423e0caa5634eb975eeae4ad2dd4691 307 Gene3D G3DSA:1.25.40.10 180 228 1.0E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS23860 128f19926e2fe3e361fa13301c174143 276 Pfam PF13490 Putative zinc-finger 4 37 2.4E-8 T 29-03-2018 IPR027383 Putative zinc-finger CDC59_RS19430 f6dd4e73094988f0d6faaa65d5cbbffa 207 SUPERFAMILY SSF75620 3 196 5.76E-45 T 29-03-2018 CDC59_RS19430 f6dd4e73094988f0d6faaa65d5cbbffa 207 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 115 131 - T 29-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CDC59_RS19430 f6dd4e73094988f0d6faaa65d5cbbffa 207 TIGRFAM TIGR03072 release_prfH: putative peptide chain release factor H 2 201 3.3E-97 T 29-03-2018 IPR017509 Putative peptide chain release factor H CDC59_RS19430 f6dd4e73094988f0d6faaa65d5cbbffa 207 Pfam PF00472 RF-1 domain 106 191 4.2E-25 T 29-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CDC59_RS19430 f6dd4e73094988f0d6faaa65d5cbbffa 207 Gene3D G3DSA:3.30.160.20 101 181 7.1E-25 T 29-03-2018 CDC59_RS19055 4af27d7129f972e3d166e17813d7648b 410 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 14 397 4.6E-104 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CDC59_RS19055 4af27d7129f972e3d166e17813d7648b 410 Gene3D G3DSA:3.40.640.10 10 269 1.5E-44 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDC59_RS19055 4af27d7129f972e3d166e17813d7648b 410 Gene3D G3DSA:3.90.1150.10 270 403 4.6E-39 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS19055 4af27d7129f972e3d166e17813d7648b 410 TIGRFAM TIGR01324 cysta_beta_ly_B: cystathionine beta-lyase 14 397 5.9E-119 T 29-03-2018 IPR006233 Cystathionine beta-lyase, bacterial GO:0004121|GO:0005737|GO:0006520 KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 CDC59_RS19055 4af27d7129f972e3d166e17813d7648b 410 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 211 225 - T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CDC59_RS19055 4af27d7129f972e3d166e17813d7648b 410 SUPERFAMILY SSF53383 62 398 1.33E-97 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS19055 4af27d7129f972e3d166e17813d7648b 410 PIRSF PIRSF001434 1 401 4.6E-125 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CDC59_RS12360 d6c1d6a2af6dc2e434d37914214d16ce 335 Gene3D G3DSA:1.10.3470.10 7 335 3.9E-62 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CDC59_RS12360 d6c1d6a2af6dc2e434d37914214d16ce 335 SUPERFAMILY SSF81345 8 332 1.44E-69 T 29-03-2018 IPR029022 ABC transporter, BtuC-like CDC59_RS12360 d6c1d6a2af6dc2e434d37914214d16ce 335 Pfam PF01032 FecCD transport family 22 332 2.5E-84 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CDC59_RS11820 cd8f71ea247b2b66d608b6f4b531f2bf 116 Pfam PF03840 Preprotein translocase SecG subunit 7 76 1.4E-20 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CDC59_RS11820 cd8f71ea247b2b66d608b6f4b531f2bf 116 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 6 76 3.3E-25 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CDC59_RS11820 cd8f71ea247b2b66d608b6f4b531f2bf 116 PRINTS PR01651 Protein-export SecG membrane protein signature 6 26 1.1E-35 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CDC59_RS11820 cd8f71ea247b2b66d608b6f4b531f2bf 116 PRINTS PR01651 Protein-export SecG membrane protein signature 57 79 1.1E-35 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CDC59_RS11820 cd8f71ea247b2b66d608b6f4b531f2bf 116 PRINTS PR01651 Protein-export SecG membrane protein signature 26 40 1.1E-35 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CDC59_RS11820 cd8f71ea247b2b66d608b6f4b531f2bf 116 PRINTS PR01651 Protein-export SecG membrane protein signature 41 57 1.1E-35 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CDC59_RS10925 3d672798bb0c7829bd347e687d297ac5 343 SUPERFAMILY SSF53850 25 331 7.36E-100 T 29-03-2018 CDC59_RS10925 3d672798bb0c7829bd347e687d297ac5 343 Gene3D G3DSA:3.40.190.10 194 342 5.6E-25 T 29-03-2018 CDC59_RS10925 3d672798bb0c7829bd347e687d297ac5 343 Gene3D G3DSA:3.40.190.10 24 188 2.9E-34 T 29-03-2018 CDC59_RS10925 3d672798bb0c7829bd347e687d297ac5 343 Pfam PF12849 PBP superfamily domain 24 303 1.1E-60 T 29-03-2018 IPR024370 PBP domain CDC59_RS10925 3d672798bb0c7829bd347e687d297ac5 343 PIRSF PIRSF002756 4 334 3.1E-106 T 29-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 CDC59_RS10925 3d672798bb0c7829bd347e687d297ac5 343 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 25 331 5.2E-129 T 29-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 CDC59_RS00680 13456a03ecdf727af0338d8e0b6bef42 66 Pfam PF00403 Heavy-metal-associated domain 3 60 1.8E-14 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CDC59_RS00680 13456a03ecdf727af0338d8e0b6bef42 66 SUPERFAMILY SSF55008 2 63 2.36E-17 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CDC59_RS00680 13456a03ecdf727af0338d8e0b6bef42 66 ProSitePatterns PS01047 Heavy-metal-associated domain. 6 35 - T 29-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CDC59_RS00680 13456a03ecdf727af0338d8e0b6bef42 66 Gene3D G3DSA:3.30.70.100 1 66 3.7E-19 T 29-03-2018 CDC59_RS23130 5a5b72e07fa8b1036539dc70198159bf 105 SUPERFAMILY SSF63592 1 97 2.22E-37 T 29-03-2018 IPR023559 Flagellar transcriptional activator FlhD GO:0044780|GO:0045893 CDC59_RS23130 5a5b72e07fa8b1036539dc70198159bf 105 Pfam PF05247 Flagellar transcriptional activator (FlhD) 1 102 1.4E-42 T 29-03-2018 IPR023559 Flagellar transcriptional activator FlhD GO:0044780|GO:0045893 CDC59_RS23130 5a5b72e07fa8b1036539dc70198159bf 105 ProDom PD015582 ACTIVATOR TRANSCRIPTIONAL TRANSCRIPTION FLAGELLUM FLHD FLAGELLAR DNA-BINDING REGULATION REGULATOR PROBABLE 10 97 7.0E-45 T 29-03-2018 IPR023559 Flagellar transcriptional activator FlhD GO:0044780|GO:0045893 CDC59_RS23130 5a5b72e07fa8b1036539dc70198159bf 105 Gene3D G3DSA:1.10.4000.10 3 102 1.6E-38 T 29-03-2018 CDC59_RS23130 5a5b72e07fa8b1036539dc70198159bf 105 Hamap MF_00725 Flagellar transcriptional regulator FlhD [flhD]. 1 104 27.851 T 29-03-2018 IPR023559 Flagellar transcriptional activator FlhD GO:0044780|GO:0045893 CDC59_RS08380 8e13e60e84735a80834fffc30c8636e2 273 Pfam PF01522 Polysaccharide deacetylase 35 183 5.0E-18 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CDC59_RS08380 8e13e60e84735a80834fffc30c8636e2 273 Gene3D G3DSA:3.20.20.370 33 265 3.3E-32 T 29-03-2018 CDC59_RS08380 8e13e60e84735a80834fffc30c8636e2 273 SUPERFAMILY SSF88713 34 261 2.72E-34 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CDC59_RS04615 9a1617ac1c9a5bb511be2c380374ffa0 405 SUPERFAMILY SSF53955 216 312 2.75E-20 T 29-03-2018 IPR023346 Lysozyme-like domain CDC59_RS04615 9a1617ac1c9a5bb511be2c380374ffa0 405 Pfam PF01464 Transglycosylase SLT domain 227 304 2.7E-14 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 CDC59_RS04615 9a1617ac1c9a5bb511be2c380374ffa0 405 Gene3D G3DSA:1.10.530.10 115 329 6.7E-19 T 29-03-2018 CDC59_RS07140 9cb33b121e71851c0dc234ce6c5e21a4 193 Pfam PF02082 Transcriptional regulator 1 83 2.3E-27 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type CDC59_RS07140 9cb33b121e71851c0dc234ce6c5e21a4 193 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 134 3.5E-43 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type CDC59_RS07140 9cb33b121e71851c0dc234ce6c5e21a4 193 Gene3D G3DSA:1.10.10.10 1 144 4.1E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS07140 9cb33b121e71851c0dc234ce6c5e21a4 193 TIGRFAM TIGR02010 IscR: iron-sulfur cluster assembly transcription factor IscR 1 137 1.6E-66 T 29-03-2018 IPR010242 Transcription factor HTH, IscR GO:0003690|GO:0003700|GO:0006355 CDC59_RS07140 9cb33b121e71851c0dc234ce6c5e21a4 193 SUPERFAMILY SSF46785 2 136 7.05E-36 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS05590 276313a45dbc4b3d45ee46cf669484a1 330 Gene3D G3DSA:1.10.10.60 274 323 5.6E-4 T 29-03-2018 CDC59_RS05590 276313a45dbc4b3d45ee46cf669484a1 330 Pfam PF03090 Replicase family 24 151 1.0E-34 T 29-03-2018 IPR004322 Plasmid replicase, bacterial CDC59_RS05590 276313a45dbc4b3d45ee46cf669484a1 330 Pfam PF08708 Primase C terminal 1 (PriCT-1) 169 237 1.6E-9 T 29-03-2018 IPR014820 Primase, C-terminal 1 CDC59_RS00290 d8b57c92cfcdc25ec46e9ce6f26d0b11 234 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 232 3.0E-20 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDC59_RS00290 d8b57c92cfcdc25ec46e9ce6f26d0b11 234 Pfam PF00072 Response regulator receiver domain 12 120 3.5E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS00290 d8b57c92cfcdc25ec46e9ce6f26d0b11 234 SUPERFAMILY SSF52172 10 191 1.85E-38 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS00290 d8b57c92cfcdc25ec46e9ce6f26d0b11 234 SMART SM00448 10 120 2.1E-35 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS00290 d8b57c92cfcdc25ec46e9ce6f26d0b11 234 SMART SM00862 156 232 6.2E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDC59_RS00290 d8b57c92cfcdc25ec46e9ce6f26d0b11 234 Gene3D G3DSA:1.10.10.10 126 234 5.5E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS00290 d8b57c92cfcdc25ec46e9ce6f26d0b11 234 Gene3D G3DSA:3.40.50.2300 5 125 1.1E-32 T 29-03-2018 CDC59_RS03760 6c4f062beb3295a52fac2ad107687812 316 Pfam PF03466 LysR substrate binding domain 88 299 4.0E-36 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS03760 6c4f062beb3295a52fac2ad107687812 316 SUPERFAMILY SSF46785 1 111 2.41E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS03760 6c4f062beb3295a52fac2ad107687812 316 Gene3D G3DSA:3.40.190.10 89 175 1.7E-10 T 29-03-2018 CDC59_RS03760 6c4f062beb3295a52fac2ad107687812 316 Gene3D G3DSA:1.10.10.10 1 87 1.2E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS03760 6c4f062beb3295a52fac2ad107687812 316 SUPERFAMILY SSF53850 89 304 8.87E-38 T 29-03-2018 CDC59_RS03760 6c4f062beb3295a52fac2ad107687812 316 Gene3D G3DSA:3.40.190.10 176 270 2.1E-23 T 29-03-2018 CDC59_RS03760 6c4f062beb3295a52fac2ad107687812 316 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 1.4E-15 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS04785 dc39e481771d6de3e12624b834c3fc6c 161 Pfam PF05014 Nucleoside 2-deoxyribosyltransferase 5 137 1.8E-43 T 29-03-2018 IPR007710 Nucleoside 2-deoxyribosyltransferase GO:0009159|GO:0050144|GO:0070694 Reactome: R-HSA-74259 CDC59_RS04785 dc39e481771d6de3e12624b834c3fc6c 161 SUPERFAMILY SSF52309 4 159 1.77E-43 T 29-03-2018 CDC59_RS04785 dc39e481771d6de3e12624b834c3fc6c 161 Gene3D G3DSA:3.40.50.450 1 161 4.1E-34 T 29-03-2018 CDC59_RS15875 a551c5713a89a5fa9889c40cbb6cedf0 397 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 179 366 3.3E-29 T 29-03-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 CDC59_RS15875 a551c5713a89a5fa9889c40cbb6cedf0 397 SUPERFAMILY SSF53335 78 393 8.74E-69 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS15875 a551c5713a89a5fa9889c40cbb6cedf0 397 Gene3D G3DSA:3.30.750.80 72 179 5.3E-38 T 29-03-2018 CDC59_RS15875 a551c5713a89a5fa9889c40cbb6cedf0 397 Gene3D G3DSA:2.30.130.10 1 68 5.7E-28 T 29-03-2018 IPR002478 PUA domain GO:0003723 CDC59_RS15875 a551c5713a89a5fa9889c40cbb6cedf0 397 SMART SM00359 2 87 1.9E-14 T 29-03-2018 IPR002478 PUA domain GO:0003723 CDC59_RS15875 a551c5713a89a5fa9889c40cbb6cedf0 397 Gene3D G3DSA:3.40.50.150 184 397 1.1E-34 T 29-03-2018 CDC59_RS15875 a551c5713a89a5fa9889c40cbb6cedf0 397 SUPERFAMILY SSF88697 1 71 7.46E-17 T 29-03-2018 IPR015947 PUA-like domain CDC59_RS19245 effca3fbbdc8d8e3d9bf100d86f0dd9e 377 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 336 355 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CDC59_RS19245 effca3fbbdc8d8e3d9bf100d86f0dd9e 377 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 117 9.5E-39 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CDC59_RS19245 effca3fbbdc8d8e3d9bf100d86f0dd9e 377 Gene3D G3DSA:2.40.110.10 121 216 5.3E-40 T 29-03-2018 CDC59_RS19245 effca3fbbdc8d8e3d9bf100d86f0dd9e 377 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 377 1.3E-49 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CDC59_RS19245 effca3fbbdc8d8e3d9bf100d86f0dd9e 377 SUPERFAMILY SSF56645 2 242 5.24E-85 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CDC59_RS19245 effca3fbbdc8d8e3d9bf100d86f0dd9e 377 PIRSF PIRSF016578 2 110 2.7E-12 T 29-03-2018 CDC59_RS19245 effca3fbbdc8d8e3d9bf100d86f0dd9e 377 PIRSF PIRSF016578 129 377 8.5E-12 T 29-03-2018 CDC59_RS19245 effca3fbbdc8d8e3d9bf100d86f0dd9e 377 Gene3D G3DSA:1.10.540.10 1 120 4.0E-42 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CDC59_RS19245 effca3fbbdc8d8e3d9bf100d86f0dd9e 377 SUPERFAMILY SSF47203 227 377 2.42E-56 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CDC59_RS19245 effca3fbbdc8d8e3d9bf100d86f0dd9e 377 Gene3D G3DSA:1.20.140.10 217 377 2.3E-60 T 29-03-2018 CDC59_RS19245 effca3fbbdc8d8e3d9bf100d86f0dd9e 377 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 217 3.3E-28 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CDC59_RS07940 5d7728c8eef58d79f42fe11b8143268e 222 SUPERFAMILY SSF54001 66 186 1.31E-40 T 29-03-2018 CDC59_RS07940 5d7728c8eef58d79f42fe11b8143268e 222 Pfam PF00877 NlpC/P60 family 79 185 5.4E-28 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CDC59_RS07940 5d7728c8eef58d79f42fe11b8143268e 222 Gene3D G3DSA:3.90.1720.10 64 197 1.3E-35 T 29-03-2018 CDC59_RS22320 05192bf554ff4121c715f7620c422a94 231 Gene3D G3DSA:3.40.50.1820 1 229 2.1E-28 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS22320 05192bf554ff4121c715f7620c422a94 231 Pfam PF01738 Dienelactone hydrolase family 13 225 7.4E-52 T 29-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 CDC59_RS22320 05192bf554ff4121c715f7620c422a94 231 SUPERFAMILY SSF53474 2 226 4.43E-42 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS19145 ce767cef4ecceae4cc28a62fa8d1ef54 261 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 55 242 4.1E-13 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS19145 ce767cef4ecceae4cc28a62fa8d1ef54 261 Gene3D G3DSA:1.10.3720.10 8 244 7.5E-35 T 29-03-2018 CDC59_RS19145 ce767cef4ecceae4cc28a62fa8d1ef54 261 SUPERFAMILY SSF161098 31 227 7.46E-31 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS15685 d0ac43687c9efdd701f6b9b36f19b501 650 Pfam PF01464 Transglycosylase SLT domain 484 587 2.2E-19 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 CDC59_RS15685 d0ac43687c9efdd701f6b9b36f19b501 650 Pfam PF14718 Soluble lytic murein transglycosylase L domain 404 460 2.5E-6 T 29-03-2018 IPR012289 Lytic transglycosylase, superhelical linker GO:0004553|GO:0042597 CDC59_RS15685 d0ac43687c9efdd701f6b9b36f19b501 650 SUPERFAMILY SSF48435 44 474 6.02E-103 T 29-03-2018 IPR016026 Lytic transglycosylase, superhelical U-shaped and linker domain GO:0004553|GO:0042597 CDC59_RS15685 d0ac43687c9efdd701f6b9b36f19b501 650 SUPERFAMILY SSF53955 475 637 2.48E-43 T 29-03-2018 IPR023346 Lysozyme-like domain CDC59_RS15685 d0ac43687c9efdd701f6b9b36f19b501 650 Gene3D G3DSA:1.10.530.10 465 628 4.3E-31 T 29-03-2018 CDC59_RS15685 d0ac43687c9efdd701f6b9b36f19b501 650 Gene3D G3DSA:1.25.20.10 44 385 3.2E-35 T 29-03-2018 CDC59_RS15685 d0ac43687c9efdd701f6b9b36f19b501 650 Gene3D G3DSA:1.10.1240.20 404 464 5.9E-19 T 29-03-2018 IPR012289 Lytic transglycosylase, superhelical linker GO:0004553|GO:0042597 CDC59_RS16420 6798e5703c02363c2ce4a1639791027a 246 SUPERFAMILY SSF56300 1 237 1.08E-50 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CDC59_RS16420 6798e5703c02363c2ce4a1639791027a 246 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 183 4.2E-27 T 29-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 CDC59_RS16420 6798e5703c02363c2ce4a1639791027a 246 PIRSF PIRSF000883 1 245 6.9E-57 T 29-03-2018 IPR011152 Phosphoesterase MJ0912 CDC59_RS16420 6798e5703c02363c2ce4a1639791027a 246 Gene3D G3DSA:3.60.21.10 1 243 8.3E-43 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CDC59_RS22815 de470336245a4f248796efba1f0ebba6 113 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 25 95 4.9E-13 T 29-03-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 CDC59_RS00675 e01459414cb4a477016f1719a449c56c 241 SUPERFAMILY SSF56925 36 241 1.75E-22 T 29-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CDC59_RS00675 e01459414cb4a477016f1719a449c56c 241 Pfam PF03922 OmpW family 25 241 2.7E-37 T 29-03-2018 IPR005618 Outer membrane protein, OmpW GO:0019867 CDC59_RS00675 e01459414cb4a477016f1719a449c56c 241 Gene3D G3DSA:2.40.160.20 22 241 4.8E-32 T 29-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CDC59_RS15360 36caedd9539c415b83588b872ba362a8 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 9.8E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS15360 36caedd9539c415b83588b872ba362a8 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 9.8E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS15360 36caedd9539c415b83588b872ba362a8 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 9.8E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS15360 36caedd9539c415b83588b872ba362a8 309 Gene3D G3DSA:1.10.10.10 1 80 3.1E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS15360 36caedd9539c415b83588b872ba362a8 309 Gene3D G3DSA:3.40.190.10 185 271 4.0E-15 T 29-03-2018 CDC59_RS15360 36caedd9539c415b83588b872ba362a8 309 SUPERFAMILY SSF46785 3 85 4.28E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS15360 36caedd9539c415b83588b872ba362a8 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 2.9E-22 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS15360 36caedd9539c415b83588b872ba362a8 309 SUPERFAMILY SSF53850 94 302 5.07E-26 T 29-03-2018 CDC59_RS15360 36caedd9539c415b83588b872ba362a8 309 Gene3D G3DSA:3.40.190.10 81 184 1.3E-10 T 29-03-2018 CDC59_RS15360 36caedd9539c415b83588b872ba362a8 309 Pfam PF03466 LysR substrate binding domain 92 296 1.6E-26 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS09355 96620fbe8d09b4ce890f98e0034e860d 187 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 7 180 15.569 T 29-03-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 CDC59_RS09355 96620fbe8d09b4ce890f98e0034e860d 187 SUPERFAMILY SSF55144 8 182 7.32E-34 T 29-03-2018 IPR009097 Cyclic phosphodiesterase CDC59_RS09355 96620fbe8d09b4ce890f98e0034e860d 187 Pfam PF02834 LigT like Phosphoesterase 14 98 2.2E-11 T 29-03-2018 IPR014051 Phosphoesterase, HXTX CDC59_RS09355 96620fbe8d09b4ce890f98e0034e860d 187 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 8 178 3.1E-19 T 29-03-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 CDC59_RS09355 96620fbe8d09b4ce890f98e0034e860d 187 Gene3D G3DSA:3.90.1140.10 7 184 1.9E-23 T 29-03-2018 CDC59_RS09105 40fbac1df2f56d4ea3a7bf6beac9846f 347 PRINTS PR00111 Alpha/beta hydrolase fold signature 97 112 5.2E-12 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS09105 40fbac1df2f56d4ea3a7bf6beac9846f 347 PRINTS PR00111 Alpha/beta hydrolase fold signature 156 169 5.2E-12 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS09105 40fbac1df2f56d4ea3a7bf6beac9846f 347 PRINTS PR00111 Alpha/beta hydrolase fold signature 142 155 5.2E-12 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS09105 40fbac1df2f56d4ea3a7bf6beac9846f 347 PRINTS PR00111 Alpha/beta hydrolase fold signature 265 279 5.2E-12 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS09105 40fbac1df2f56d4ea3a7bf6beac9846f 347 PRINTS PR00412 Epoxide hydrolase signature 142 155 5.6E-6 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CDC59_RS09105 40fbac1df2f56d4ea3a7bf6beac9846f 347 PRINTS PR00412 Epoxide hydrolase signature 97 112 5.6E-6 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CDC59_RS09105 40fbac1df2f56d4ea3a7bf6beac9846f 347 PRINTS PR00412 Epoxide hydrolase signature 156 169 5.6E-6 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CDC59_RS09105 40fbac1df2f56d4ea3a7bf6beac9846f 347 PRINTS PR00412 Epoxide hydrolase signature 312 334 5.6E-6 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CDC59_RS09105 40fbac1df2f56d4ea3a7bf6beac9846f 347 SUPERFAMILY SSF53474 36 336 6.89E-61 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS09105 40fbac1df2f56d4ea3a7bf6beac9846f 347 Gene3D G3DSA:3.40.50.1820 25 338 2.8E-61 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS09105 40fbac1df2f56d4ea3a7bf6beac9846f 347 Pfam PF00561 alpha/beta hydrolase fold 74 321 2.6E-22 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS09100 7633d4f15e8c903c81177ba8bdecd655 306 SUPERFAMILY SSF103481 221 304 1.57E-6 T 29-03-2018 CDC59_RS09100 7633d4f15e8c903c81177ba8bdecd655 306 Pfam PF00892 EamA-like transporter family 21 148 3.6E-6 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CDC59_RS09100 7633d4f15e8c903c81177ba8bdecd655 306 Pfam PF00892 EamA-like transporter family 163 299 9.5E-7 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CDC59_RS09100 7633d4f15e8c903c81177ba8bdecd655 306 SUPERFAMILY SSF103481 56 151 8.63E-9 T 29-03-2018 CDC59_RS13630 ae1a86c60ee5f0a7fa3eec36ca320c11 135 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 3 123 6.4E-25 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CDC59_RS13630 ae1a86c60ee5f0a7fa3eec36ca320c11 135 ProSitePatterns PS00934 Glyoxalase I signature 1. 5 26 - T 29-03-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 CDC59_RS13630 ae1a86c60ee5f0a7fa3eec36ca320c11 135 SUPERFAMILY SSF54593 1 128 2.15E-34 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CDC59_RS13630 ae1a86c60ee5f0a7fa3eec36ca320c11 135 TIGRFAM TIGR00068 glyox_I: lactoylglutathione lyase 2 131 7.6E-65 T 29-03-2018 IPR004361 Glyoxalase I GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 CDC59_RS13630 ae1a86c60ee5f0a7fa3eec36ca320c11 135 Gene3D G3DSA:3.10.180.10 1 133 4.6E-37 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CDC59_RS19830 5ddd79570cbc4ae1d93d1e18c193f09a 523 SUPERFAMILY SSF56672 28 239 8.15E-25 T 29-03-2018 CDC59_RS07275 28b551e13e92f44e81d45e780346e3b5 243 Gene3D G3DSA:3.30.950.10 129 238 1.1E-24 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CDC59_RS07275 28b551e13e92f44e81d45e780346e3b5 243 SUPERFAMILY SSF53790 3 238 1.57E-58 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CDC59_RS07275 28b551e13e92f44e81d45e780346e3b5 243 PIRSF PIRSF005917 1 239 2.6E-49 T 29-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CDC59_RS07275 28b551e13e92f44e81d45e780346e3b5 243 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 26 222 3.1E-10 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CDC59_RS07275 28b551e13e92f44e81d45e780346e3b5 243 Gene3D G3DSA:3.40.1010.10 2 128 7.4E-28 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CDC59_RS02270 c6e658ac978ba270bd8459eebf86e5ca 138 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 38.346 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS02270 c6e658ac978ba270bd8459eebf86e5ca 138 SUPERFAMILY SSF54686 1 134 1.57E-53 T 29-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CDC59_RS02270 c6e658ac978ba270bd8459eebf86e5ca 138 Gene3D G3DSA:3.90.1170.10 1 137 5.4E-48 T 29-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CDC59_RS02270 c6e658ac978ba270bd8459eebf86e5ca 138 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 29-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS02270 c6e658ac978ba270bd8459eebf86e5ca 138 PRINTS PR00060 Ribosomal protein L16 signature 58 87 9.1E-39 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS02270 c6e658ac978ba270bd8459eebf86e5ca 138 PRINTS PR00060 Ribosomal protein L16 signature 88 117 9.1E-39 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS02270 c6e658ac978ba270bd8459eebf86e5ca 138 PRINTS PR00060 Ribosomal protein L16 signature 24 36 9.1E-39 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS02270 c6e658ac978ba270bd8459eebf86e5ca 138 PRINTS PR00060 Ribosomal protein L16 signature 42 53 9.1E-39 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS02270 c6e658ac978ba270bd8459eebf86e5ca 138 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 5.5E-59 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS02270 c6e658ac978ba270bd8459eebf86e5ca 138 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 3.0E-48 T 29-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CDC59_RS09980 4a7be28644ccc0558231b28400fdfadf 262 SMART SM00382 32 226 6.2E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS09980 4a7be28644ccc0558231b28400fdfadf 262 Pfam PF00005 ABC transporter 24 179 2.1E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS09980 4a7be28644ccc0558231b28400fdfadf 262 SUPERFAMILY SSF52540 6 248 1.78E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS09980 4a7be28644ccc0558231b28400fdfadf 262 Gene3D G3DSA:3.40.50.300 2 257 3.1E-52 T 29-03-2018 CDC59_RS09980 4a7be28644ccc0558231b28400fdfadf 262 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 226 248 1.2E-10 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CDC59_RS16710 56fc3d613206f4dc8d25ffc9afc4afeb 672 Gene3D G3DSA:3.40.50.2000 451 642 1.1E-22 T 29-03-2018 CDC59_RS16710 56fc3d613206f4dc8d25ffc9afc4afeb 672 Pfam PF13432 Tetratricopeptide repeat 90 153 4.7E-8 T 29-03-2018 CDC59_RS16710 56fc3d613206f4dc8d25ffc9afc4afeb 672 Pfam PF13432 Tetratricopeptide repeat 167 221 4.9E-6 T 29-03-2018 CDC59_RS16710 56fc3d613206f4dc8d25ffc9afc4afeb 672 Pfam PF13844 Glycosyl transferase family 41 306 458 1.2E-37 T 29-03-2018 IPR029489 O-GlcNAc transferase, C-terminal Reactome: R-HSA-3214847|Reactome: R-HSA-5689603 CDC59_RS16710 56fc3d613206f4dc8d25ffc9afc4afeb 672 Pfam PF13844 Glycosyl transferase family 41 467 658 9.7E-50 T 29-03-2018 IPR029489 O-GlcNAc transferase, C-terminal Reactome: R-HSA-3214847|Reactome: R-HSA-5689603 CDC59_RS16710 56fc3d613206f4dc8d25ffc9afc4afeb 672 SUPERFAMILY SSF48452 299 341 6.45E-17 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS16710 56fc3d613206f4dc8d25ffc9afc4afeb 672 SUPERFAMILY SSF48452 551 613 6.45E-17 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS16710 56fc3d613206f4dc8d25ffc9afc4afeb 672 SUPERFAMILY SSF48452 414 489 6.45E-17 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS16710 56fc3d613206f4dc8d25ffc9afc4afeb 672 SUPERFAMILY SSF48452 123 205 6.45E-17 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS16710 56fc3d613206f4dc8d25ffc9afc4afeb 672 SMART SM00028 85 118 1.4 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CDC59_RS16710 56fc3d613206f4dc8d25ffc9afc4afeb 672 SMART SM00028 187 218 170.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CDC59_RS16710 56fc3d613206f4dc8d25ffc9afc4afeb 672 SMART SM00028 119 152 0.0041 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CDC59_RS16710 56fc3d613206f4dc8d25ffc9afc4afeb 672 SMART SM00028 51 84 56.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CDC59_RS16710 56fc3d613206f4dc8d25ffc9afc4afeb 672 SMART SM00028 153 186 0.0041 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CDC59_RS16710 56fc3d613206f4dc8d25ffc9afc4afeb 672 Gene3D G3DSA:1.25.40.10 1 122 4.2E-18 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS16710 56fc3d613206f4dc8d25ffc9afc4afeb 672 Gene3D G3DSA:1.25.40.10 184 246 2.6E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS16710 56fc3d613206f4dc8d25ffc9afc4afeb 672 Gene3D G3DSA:1.10.287.1110 172 183 0.0046 T 29-03-2018 CDC59_RS16710 56fc3d613206f4dc8d25ffc9afc4afeb 672 SUPERFAMILY SSF48452 57 224 3.41E-29 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS16710 56fc3d613206f4dc8d25ffc9afc4afeb 672 Gene3D G3DSA:1.25.40.10 123 171 4.6E-16 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS16125 159c5f000075c674451cc00538b9cb5c 95 SMART SM00528 56 94 5.0E-9 T 29-03-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 CDC59_RS16125 159c5f000075c674451cc00538b9cb5c 95 Gene3D G3DSA:4.10.430.10 62 94 1.3E-14 T 29-03-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 CDC59_RS16125 159c5f000075c674451cc00538b9cb5c 95 SUPERFAMILY SSF81273 59 94 1.88E-9 T 29-03-2018 CDC59_RS16125 159c5f000075c674451cc00538b9cb5c 95 Pfam PF00816 H-NS histone family 6 87 2.8E-24 T 29-03-2018 IPR001801 Histone-like protein H-NS GO:0003677|GO:0005622|GO:0006355 CDC59_RS03345 48fe7f881870ff33df5ae2786e19cbe5 282 SUPERFAMILY SSF103481 199 271 4.18E-11 T 29-03-2018 CDC59_RS03345 48fe7f881870ff33df5ae2786e19cbe5 282 Pfam PF00892 EamA-like transporter family 140 268 8.5E-16 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CDC59_RS03950 514db0216db7f522000c88fa6a121c8d 497 SUPERFAMILY SSF55103 203 472 1.39E-73 T 29-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CDC59_RS03950 514db0216db7f522000c88fa6a121c8d 497 Gene3D G3DSA:1.10.45.10 430 468 4.5E-10 T 29-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CDC59_RS03950 514db0216db7f522000c88fa6a121c8d 497 SUPERFAMILY SSF56176 18 229 4.67E-69 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CDC59_RS03950 514db0216db7f522000c88fa6a121c8d 497 Gene3D G3DSA:3.30.43.10 3 105 9.8E-24 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CDC59_RS03950 514db0216db7f522000c88fa6a121c8d 497 Gene3D G3DSA:3.40.50.280 239 369 3.0E-4 T 29-03-2018 CDC59_RS03950 514db0216db7f522000c88fa6a121c8d 497 Gene3D G3DSA:3.30.465.10 106 238 1.7E-38 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CDC59_RS03950 514db0216db7f522000c88fa6a121c8d 497 Pfam PF02913 FAD linked oxidases, C-terminal domain 228 468 2.9E-64 T 29-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CDC59_RS03950 514db0216db7f522000c88fa6a121c8d 497 Pfam PF01565 FAD binding domain 54 192 2.2E-42 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CDC59_RS03120 0076b13409ab5a3ad65f48faa6dcac30 546 Gene3D G3DSA:3.40.1190.10 150 399 8.3E-66 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CDC59_RS03120 0076b13409ab5a3ad65f48faa6dcac30 546 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 55 538 33.329 T 29-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDC59_RS03120 0076b13409ab5a3ad65f48faa6dcac30 546 SUPERFAMILY SSF53623 169 308 1.7E-47 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CDC59_RS03120 0076b13409ab5a3ad65f48faa6dcac30 546 SUPERFAMILY SSF53623 340 397 1.7E-47 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CDC59_RS03120 0076b13409ab5a3ad65f48faa6dcac30 546 Gene3D G3DSA:3.40.50.720 57 149 9.4E-12 T 29-03-2018 CDC59_RS03120 0076b13409ab5a3ad65f48faa6dcac30 546 SUPERFAMILY SSF53244 399 538 2.52E-42 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CDC59_RS03120 0076b13409ab5a3ad65f48faa6dcac30 546 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 57 536 1.7E-113 T 29-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CDC59_RS03120 0076b13409ab5a3ad65f48faa6dcac30 546 Gene3D G3DSA:3.90.190.20 404 537 3.2E-38 T 29-03-2018 CDC59_RS03120 0076b13409ab5a3ad65f48faa6dcac30 546 Pfam PF02875 Mur ligase family, glutamate ligase domain 401 470 1.7E-6 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CDC59_RS03120 0076b13409ab5a3ad65f48faa6dcac30 546 SUPERFAMILY SSF51984 53 148 1.06E-12 T 29-03-2018 CDC59_RS03120 0076b13409ab5a3ad65f48faa6dcac30 546 Pfam PF08245 Mur ligase middle domain 174 380 4.0E-27 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CDC59_RS11000 5f9a80046faf42f5827780b95d9bf8d3 151 Hamap MF_00042 Ribonuclease H [rnhA]. 1 149 34.236 T 29-03-2018 IPR022892 Ribonuclease HI GO:0004523 CDC59_RS11000 5f9a80046faf42f5827780b95d9bf8d3 151 SUPERFAMILY SSF53098 2 141 1.52E-57 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDC59_RS11000 5f9a80046faf42f5827780b95d9bf8d3 151 Pfam PF00075 RNase H 2 140 5.3E-50 T 29-03-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 CDC59_RS11000 5f9a80046faf42f5827780b95d9bf8d3 151 Gene3D G3DSA:3.30.420.10 1 150 9.9E-53 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDC59_RS10555 48771a0a8006a352b34124e3a0380f19 476 Pfam PF13520 Amino acid permease 26 430 3.1E-65 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CDC59_RS10555 48771a0a8006a352b34124e3a0380f19 476 PIRSF PIRSF006060 6 474 2.3E-94 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CDC59_RS11785 e4ae8f27f971bd32d0ea6f4b176fd12b 431 SUPERFAMILY SSF140490 331 428 4.84E-37 T 29-03-2018 CDC59_RS11785 e4ae8f27f971bd32d0ea6f4b176fd12b 431 Gene3D G3DSA:3.10.560.10 238 331 6.5E-6 T 29-03-2018 CDC59_RS11785 e4ae8f27f971bd32d0ea6f4b176fd12b 431 SUPERFAMILY SSF142019 18 244 3.66E-82 T 29-03-2018 CDC59_RS11785 e4ae8f27f971bd32d0ea6f4b176fd12b 431 SUPERFAMILY SSF142984 246 329 7.19E-26 T 29-03-2018 CDC59_RS11785 e4ae8f27f971bd32d0ea6f4b176fd12b 431 SMART SM00928 334 379 2.7E-24 T 29-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS11785 e4ae8f27f971bd32d0ea6f4b176fd12b 431 TIGRFAM TIGR01959 nuoF_fam: NADH oxidoreductase (quinone), F subunit 20 420 3.4E-193 T 29-03-2018 IPR011537 NADH ubiquinone oxidoreductase, F subunit GO:0010181|GO:0016651|GO:0051287|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS11785 e4ae8f27f971bd32d0ea6f4b176fd12b 431 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 338 419 6.6E-30 T 29-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS11785 e4ae8f27f971bd32d0ea6f4b176fd12b 431 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 53 224 7.5E-46 T 29-03-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS11785 e4ae8f27f971bd32d0ea6f4b176fd12b 431 Pfam PF10531 SLBB domain 248 296 2.5E-14 T 29-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS11785 e4ae8f27f971bd32d0ea6f4b176fd12b 431 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 347 358 - T 29-03-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS08050 c51617689ccf0f2839dd9370d1291e90 99 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 77 3.8E-13 T 29-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CDC59_RS08050 c51617689ccf0f2839dd9370d1291e90 99 SUPERFAMILY SSF54909 1 98 4.54E-26 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CDC59_RS08050 c51617689ccf0f2839dd9370d1291e90 99 Gene3D G3DSA:3.30.70.100 1 96 2.1E-19 T 29-03-2018 CDC59_RS03480 dbdc6d2e35fdc6c48bd469f3be645cbe 385 SUPERFAMILY SSF51126 169 374 1.26E-38 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CDC59_RS03480 dbdc6d2e35fdc6c48bd469f3be645cbe 385 Gene3D G3DSA:2.160.20.10 162 369 2.1E-44 T 29-03-2018 IPR012334 Pectin lyase fold CDC59_RS03480 dbdc6d2e35fdc6c48bd469f3be645cbe 385 Pfam PF03211 Pectate lyase 161 348 6.1E-31 T 29-03-2018 IPR004898 Pectate lyase PlyH/PlyE-like GO:0005576|GO:0030570 KEGG: 00040+4.2.2.2 CDC59_RS08995 059217046533e90a51c79615f9020fd3 368 SUPERFAMILY SSF89796 12 367 8.24E-108 T 29-03-2018 IPR023606 CoA-transferase family III domain CDC59_RS08995 059217046533e90a51c79615f9020fd3 368 Pfam PF02515 CoA-transferase family III 14 356 2.7E-97 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 CDC59_RS08995 059217046533e90a51c79615f9020fd3 368 Gene3D G3DSA:3.40.50.10540 9 368 1.5E-111 T 29-03-2018 IPR023606 CoA-transferase family III domain CDC59_RS12355 4a32261785e19a4dbd299305435f3987 279 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS12355 4a32261785e19a4dbd299305435f3987 279 SMART SM00382 46 235 3.1E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS12355 4a32261785e19a4dbd299305435f3987 279 Pfam PF00005 ABC transporter 38 186 3.0E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS12355 4a32261785e19a4dbd299305435f3987 279 SUPERFAMILY SSF52540 18 249 4.55E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS12355 4a32261785e19a4dbd299305435f3987 279 Gene3D G3DSA:3.40.50.300 19 254 1.4E-51 T 29-03-2018 CDC59_RS07765 fade03cabbbbbbb2aa17e5d3cdc9c6b0 188 Pfam PF13649 Methyltransferase domain 31 106 1.5E-9 T 29-03-2018 CDC59_RS07765 fade03cabbbbbbb2aa17e5d3cdc9c6b0 188 Gene3D G3DSA:3.40.50.150 10 170 3.5E-23 T 29-03-2018 CDC59_RS07765 fade03cabbbbbbb2aa17e5d3cdc9c6b0 188 SUPERFAMILY SSF53335 10 172 4.92E-30 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS15905 6bfccd08c2a0f899c63044df35fd59d4 359 SMART SM00833 265 358 6.4E-16 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CDC59_RS15905 6bfccd08c2a0f899c63044df35fd59d4 359 Gene3D G3DSA:3.30.1220.10 218 359 3.3E-27 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CDC59_RS15905 6bfccd08c2a0f899c63044df35fd59d4 359 SUPERFAMILY SSF90002 265 358 1.1E-25 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CDC59_RS15905 6bfccd08c2a0f899c63044df35fd59d4 359 Gene3D G3DSA:3.40.50.300 2 206 4.6E-48 T 29-03-2018 CDC59_RS15905 6bfccd08c2a0f899c63044df35fd59d4 359 SUPERFAMILY SSF52540 5 206 1.04E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS15905 6bfccd08c2a0f899c63044df35fd59d4 359 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 265 358 4.9E-21 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CDC59_RS15905 6bfccd08c2a0f899c63044df35fd59d4 359 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 6 186 5.4E-55 T 29-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CDC59_RS10405 ffc2f4edde76586cb322d43ec0359454 195 Pfam PF00293 NUDIX domain 38 140 3.6E-13 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CDC59_RS10405 ffc2f4edde76586cb322d43ec0359454 195 Gene3D G3DSA:3.90.79.10 36 183 3.2E-29 T 29-03-2018 CDC59_RS10405 ffc2f4edde76586cb322d43ec0359454 195 ProSitePatterns PS00893 Nudix box signature. 70 91 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CDC59_RS10405 ffc2f4edde76586cb322d43ec0359454 195 SUPERFAMILY SSF55811 2 162 2.03E-41 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CDC59_RS10405 ffc2f4edde76586cb322d43ec0359454 195 PRINTS PR00502 NUDIX hydrolase family signature 65 79 2.4E-5 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CDC59_RS10405 ffc2f4edde76586cb322d43ec0359454 195 PRINTS PR00502 NUDIX hydrolase family signature 79 94 2.4E-5 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CDC59_RS10405 ffc2f4edde76586cb322d43ec0359454 195 Pfam PF14803 Nudix N-terminal 2 34 1.8E-17 T 29-03-2018 IPR029401 Nudix hydrolase, N-terminal KEGG: 00230+3.6.1.13|KEGG: 00740+3.6.1.18 CDC59_RS10405 ffc2f4edde76586cb322d43ec0359454 195 Gene3D G3DSA:2.20.70.10 1 34 1.3E-16 T 29-03-2018 CDC59_RS09150 19686c30322678af846f5fb901f1fee6 247 Pfam PF00318 Ribosomal protein S2 8 223 1.7E-91 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS09150 19686c30322678af846f5fb901f1fee6 247 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 5 16 - T 29-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 CDC59_RS09150 19686c30322678af846f5fb901f1fee6 247 PRINTS PR00395 Ribosomal protein S2 signature 195 209 2.3E-35 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS09150 19686c30322678af846f5fb901f1fee6 247 PRINTS PR00395 Ribosomal protein S2 signature 36 45 2.3E-35 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS09150 19686c30322678af846f5fb901f1fee6 247 PRINTS PR00395 Ribosomal protein S2 signature 174 185 2.3E-35 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS09150 19686c30322678af846f5fb901f1fee6 247 PRINTS PR00395 Ribosomal protein S2 signature 157 174 2.3E-35 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS09150 19686c30322678af846f5fb901f1fee6 247 PRINTS PR00395 Ribosomal protein S2 signature 86 103 2.3E-35 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS09150 19686c30322678af846f5fb901f1fee6 247 PRINTS PR00395 Ribosomal protein S2 signature 5 23 2.3E-35 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS09150 19686c30322678af846f5fb901f1fee6 247 Gene3D G3DSA:3.40.50.10490 4 246 9.7E-89 T 29-03-2018 CDC59_RS09150 19686c30322678af846f5fb901f1fee6 247 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 225 3.1E-98 T 29-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS09150 19686c30322678af846f5fb901f1fee6 247 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 1 224 40.09 T 29-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS09150 19686c30322678af846f5fb901f1fee6 247 SUPERFAMILY SSF52313 5 230 6.54E-92 T 29-03-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain CDC59_RS17395 a9924fc86983f4f7781ff3e9f101a0a6 586 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 457 490 1.4E-4 T 29-03-2018 IPR006530 YD repeat CDC59_RS17395 a9924fc86983f4f7781ff3e9f101a0a6 586 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 503 544 1.8E-7 T 29-03-2018 IPR006530 YD repeat CDC59_RS17395 a9924fc86983f4f7781ff3e9f101a0a6 586 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 116 156 1.3E-7 T 29-03-2018 IPR006530 YD repeat CDC59_RS17395 a9924fc86983f4f7781ff3e9f101a0a6 586 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 158 198 4.5E-8 T 29-03-2018 IPR006530 YD repeat CDC59_RS17395 a9924fc86983f4f7781ff3e9f101a0a6 586 Pfam PF05593 RHS Repeat 457 495 5.1E-9 T 29-03-2018 IPR031325 RHS repeat CDC59_RS17395 a9924fc86983f4f7781ff3e9f101a0a6 586 Pfam PF05593 RHS Repeat 158 195 3.0E-9 T 29-03-2018 IPR031325 RHS repeat CDC59_RS17395 a9924fc86983f4f7781ff3e9f101a0a6 586 Pfam PF05593 RHS Repeat 524 561 3.8E-6 T 29-03-2018 IPR031325 RHS repeat CDC59_RS17395 a9924fc86983f4f7781ff3e9f101a0a6 586 Pfam PF05593 RHS Repeat 116 152 2.3E-8 T 29-03-2018 IPR031325 RHS repeat CDC59_RS17395 a9924fc86983f4f7781ff3e9f101a0a6 586 Pfam PF05593 RHS Repeat 503 538 1.7E-8 T 29-03-2018 IPR031325 RHS repeat CDC59_RS08435 b6c1f177e5c69b29de7a016daecbe8c4 438 Pfam PF13416 Bacterial extracellular solute-binding protein 44 369 2.2E-43 T 29-03-2018 CDC59_RS08435 b6c1f177e5c69b29de7a016daecbe8c4 438 SUPERFAMILY SSF53850 26 424 5.98E-74 T 29-03-2018 CDC59_RS08435 b6c1f177e5c69b29de7a016daecbe8c4 438 Gene3D G3DSA:3.40.190.10 163 438 1.8E-37 T 29-03-2018 CDC59_RS08435 b6c1f177e5c69b29de7a016daecbe8c4 438 Gene3D G3DSA:3.40.190.10 26 162 1.2E-16 T 29-03-2018 CDC59_RS12015 855be2a36f13922c60938289e7eca65c 144 Pfam PF05433 Glycine zipper 2TM domain 52 92 4.1E-10 T 29-03-2018 IPR008816 Glycine zipper 2TM domain GO:0019867 CDC59_RS15835 f2848f2483281a697547f8f29e3a3f96 347 Gene3D G3DSA:3.30.420.40 8 173 1.5E-39 T 29-03-2018 CDC59_RS15835 f2848f2483281a697547f8f29e3a3f96 347 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 9 340 3.4E-156 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CDC59_RS15835 f2848f2483281a697547f8f29e3a3f96 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 137 156 1.9E-63 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CDC59_RS15835 f2848f2483281a697547f8f29e3a3f96 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 305 331 1.9E-63 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CDC59_RS15835 f2848f2483281a697547f8f29e3a3f96 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 73 96 1.9E-63 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CDC59_RS15835 f2848f2483281a697547f8f29e3a3f96 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 53 71 1.9E-63 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CDC59_RS15835 f2848f2483281a697547f8f29e3a3f96 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 192 212 1.9E-63 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CDC59_RS15835 f2848f2483281a697547f8f29e3a3f96 347 Gene3D G3DSA:3.90.640.10 191 256 4.3E-28 T 29-03-2018 CDC59_RS15835 f2848f2483281a697547f8f29e3a3f96 347 SUPERFAMILY SSF53067 154 339 2.82E-48 T 29-03-2018 CDC59_RS15835 f2848f2483281a697547f8f29e3a3f96 347 Gene3D G3DSA:3.30.420.40 257 322 7.0E-8 T 29-03-2018 CDC59_RS15835 f2848f2483281a697547f8f29e3a3f96 347 SUPERFAMILY SSF53067 9 153 2.06E-37 T 29-03-2018 CDC59_RS15835 f2848f2483281a697547f8f29e3a3f96 347 Pfam PF06723 MreB/Mbl protein 11 340 6.0E-150 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CDC59_RS19235 ff8c901207748bfcd171a74b82dbd3e6 515 Gene3D G3DSA:3.40.309.10 281 476 1.5E-59 T 29-03-2018 CDC59_RS19235 ff8c901207748bfcd171a74b82dbd3e6 515 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 292 303 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CDC59_RS19235 ff8c901207748bfcd171a74b82dbd3e6 515 SUPERFAMILY SSF53720 18 500 4.58E-148 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CDC59_RS19235 ff8c901207748bfcd171a74b82dbd3e6 515 Gene3D G3DSA:3.40.605.10 10 280 7.4E-91 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CDC59_RS19235 ff8c901207748bfcd171a74b82dbd3e6 515 Pfam PF00171 Aldehyde dehydrogenase family 30 494 7.4E-143 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CDC59_RS19235 ff8c901207748bfcd171a74b82dbd3e6 515 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 22 498 9.8E-225 T 29-03-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373|Reactome: R-HSA-70895 CDC59_RS09695 1d30e6bed6c84d11d2ae9fecfe149e2a 701 SUPERFAMILY SSF51126 195 270 1.19E-47 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CDC59_RS09695 1d30e6bed6c84d11d2ae9fecfe149e2a 701 SUPERFAMILY SSF51126 384 679 1.19E-47 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CDC59_RS09695 1d30e6bed6c84d11d2ae9fecfe149e2a 701 SUPERFAMILY SSF51126 307 341 1.19E-47 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CDC59_RS09695 1d30e6bed6c84d11d2ae9fecfe149e2a 701 Gene3D G3DSA:2.60.40.10 67 182 4.1E-16 T 29-03-2018 IPR013783 Immunoglobulin-like fold CDC59_RS09695 1d30e6bed6c84d11d2ae9fecfe149e2a 701 Pfam PF00041 Fibronectin type III domain 69 168 1.8E-5 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 CDC59_RS09695 1d30e6bed6c84d11d2ae9fecfe149e2a 701 SUPERFAMILY SSF49265 62 185 1.36E-12 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 CDC59_RS09695 1d30e6bed6c84d11d2ae9fecfe149e2a 701 SMART SM00060 66 171 1.2E-5 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 CDC59_RS09695 1d30e6bed6c84d11d2ae9fecfe149e2a 701 Gene3D G3DSA:2.160.20.10 185 701 3.5E-67 T 29-03-2018 IPR012334 Pectin lyase fold CDC59_RS09695 1d30e6bed6c84d11d2ae9fecfe149e2a 701 Pfam PF00295 Glycosyl hydrolases family 28 404 559 2.0E-16 T 29-03-2018 IPR000743 Glycoside hydrolase, family 28 GO:0004650|GO:0005975 CDC59_RS13065 16606a33c77175b7fdb736670af6c354 417 Gene3D G3DSA:3.30.420.40 185 394 7.3E-30 T 29-03-2018 CDC59_RS13065 16606a33c77175b7fdb736670af6c354 417 PRINTS PR00301 70kDa heat shock protein signature 120 140 5.4E-6 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CDC59_RS13065 16606a33c77175b7fdb736670af6c354 417 PRINTS PR00301 70kDa heat shock protein signature 186 196 5.4E-6 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CDC59_RS13065 16606a33c77175b7fdb736670af6c354 417 PRINTS PR00301 70kDa heat shock protein signature 4 17 5.4E-6 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CDC59_RS13065 16606a33c77175b7fdb736670af6c354 417 PRINTS PR00301 70kDa heat shock protein signature 32 44 5.4E-6 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CDC59_RS13065 16606a33c77175b7fdb736670af6c354 417 SUPERFAMILY SSF53067 6 171 1.32E-30 T 29-03-2018 CDC59_RS13065 16606a33c77175b7fdb736670af6c354 417 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 370 384 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CDC59_RS13065 16606a33c77175b7fdb736670af6c354 417 SUPERFAMILY SSF53067 175 243 8.84E-32 T 29-03-2018 CDC59_RS13065 16606a33c77175b7fdb736670af6c354 417 SUPERFAMILY SSF53067 292 413 8.84E-32 T 29-03-2018 CDC59_RS13065 16606a33c77175b7fdb736670af6c354 417 Gene3D G3DSA:3.30.420.40 2 184 8.1E-36 T 29-03-2018 CDC59_RS13065 16606a33c77175b7fdb736670af6c354 417 Pfam PF00012 Hsp70 protein 6 226 4.1E-15 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CDC59_RS13065 16606a33c77175b7fdb736670af6c354 417 Pfam PF00012 Hsp70 protein 297 389 2.3E-9 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CDC59_RS15115 90006b230991e574a4d94b2a1591f22a 496 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 130 460 1.2E-12 T 29-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CDC59_RS15115 90006b230991e574a4d94b2a1591f22a 496 SUPERFAMILY SSF53590 128 398 2.75E-28 T 29-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CDC59_RS15115 90006b230991e574a4d94b2a1591f22a 496 Gene3D G3DSA:3.90.245.10 121 486 5.2E-33 T 29-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CDC59_RS11645 e9f32b5da3026e66345ad20ce4aa97e4 243 PIRSF PIRSF009467 17 243 3.9E-66 T 29-03-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 CDC59_RS11645 e9f32b5da3026e66345ad20ce4aa97e4 243 Hamap MF_01385 Urease accessory protein UreF [ureF]. 20 243 30.133 T 29-03-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 CDC59_RS11645 e9f32b5da3026e66345ad20ce4aa97e4 243 Pfam PF01730 UreF 52 198 1.2E-38 T 29-03-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 CDC59_RS05110 b26b078e9dff4881e7ed76dfeff901cb 193 Pfam PF00293 NUDIX domain 48 144 4.1E-13 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CDC59_RS05110 b26b078e9dff4881e7ed76dfeff901cb 193 SUPERFAMILY SSF55811 3 166 1.04E-28 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CDC59_RS05110 b26b078e9dff4881e7ed76dfeff901cb 193 Gene3D G3DSA:2.20.70.10 5 29 2.9E-9 T 29-03-2018 CDC59_RS05110 b26b078e9dff4881e7ed76dfeff901cb 193 Gene3D G3DSA:3.90.79.10 30 148 2.5E-19 T 29-03-2018 CDC59_RS05190 4f6dd42b53de20781dc0a7b2fb42210c 122 Gene3D G3DSA:1.20.5.170 4 99 7.6E-8 T 29-03-2018 CDC59_RS10530 d9ff72643d6548489b8622d93b8474e0 269 Gene3D G3DSA:3.60.10.10 1 267 2.2E-52 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CDC59_RS10530 d9ff72643d6548489b8622d93b8474e0 269 ProSitePatterns PS00728 AP endonucleases family 1 signature 3. 223 234 - T 29-03-2018 IPR020848 AP endonuclease 1, conserved site GO:0003677|GO:0004519|GO:0005622|GO:0006281 Reactome: R-HSA-110357|Reactome: R-HSA-110362|Reactome: R-HSA-110373|Reactome: R-HSA-5651801|Reactome: R-HSA-73930|Reactome: R-HSA-73933 CDC59_RS10530 d9ff72643d6548489b8622d93b8474e0 269 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 265 3.1E-74 T 29-03-2018 CDC59_RS10530 d9ff72643d6548489b8622d93b8474e0 269 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 259 2.0E-17 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CDC59_RS10530 d9ff72643d6548489b8622d93b8474e0 269 SUPERFAMILY SSF56219 1 266 8.64E-78 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CDC59_RS10530 d9ff72643d6548489b8622d93b8474e0 269 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 266 1.6E-68 T 29-03-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 CDC59_RS02935 5ca2c55772b748f5bb78f4bcc523f7df 124 SUPERFAMILY SSF110069 5 124 1.7E-49 T 29-03-2018 IPR007474 ApaG domain CDC59_RS02935 5ca2c55772b748f5bb78f4bcc523f7df 124 Pfam PF04379 ApaG domain 16 101 4.5E-35 T 29-03-2018 IPR007474 ApaG domain CDC59_RS02935 5ca2c55772b748f5bb78f4bcc523f7df 124 Gene3D G3DSA:2.60.40.1470 2 124 5.4E-45 T 29-03-2018 IPR007474 ApaG domain CDC59_RS02935 5ca2c55772b748f5bb78f4bcc523f7df 124 Hamap MF_00791 Protein ApaG [apaG]. 1 124 32.536 T 29-03-2018 IPR023065 Uncharacterised protein family ApaG CDC59_RS05740 66f8250365719b2b2d4f3fd2cc72afbd 1033 PRINTS PR00702 Acriflavin resistance protein family signature 383 407 9.6E-52 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS05740 66f8250365719b2b2d4f3fd2cc72afbd 1033 PRINTS PR00702 Acriflavin resistance protein family signature 328 351 9.6E-52 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS05740 66f8250365719b2b2d4f3fd2cc72afbd 1033 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 9.6E-52 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS05740 66f8250365719b2b2d4f3fd2cc72afbd 1033 PRINTS PR00702 Acriflavin resistance protein family signature 355 376 9.6E-52 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS05740 66f8250365719b2b2d4f3fd2cc72afbd 1033 PRINTS PR00702 Acriflavin resistance protein family signature 436 459 9.6E-52 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS05740 66f8250365719b2b2d4f3fd2cc72afbd 1033 PRINTS PR00702 Acriflavin resistance protein family signature 533 550 9.6E-52 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS05740 66f8250365719b2b2d4f3fd2cc72afbd 1033 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 9.6E-52 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS05740 66f8250365719b2b2d4f3fd2cc72afbd 1033 PRINTS PR00702 Acriflavin resistance protein family signature 461 484 9.6E-52 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS05740 66f8250365719b2b2d4f3fd2cc72afbd 1033 SUPERFAMILY SSF82693 139 181 9.94E-9 T 29-03-2018 CDC59_RS05740 66f8250365719b2b2d4f3fd2cc72afbd 1033 SUPERFAMILY SSF82693 267 311 9.94E-9 T 29-03-2018 CDC59_RS05740 66f8250365719b2b2d4f3fd2cc72afbd 1033 SUPERFAMILY SSF82714 695 781 3.01E-8 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS05740 66f8250365719b2b2d4f3fd2cc72afbd 1033 SUPERFAMILY SSF82693 41 131 3.66E-18 T 29-03-2018 CDC59_RS05740 66f8250365719b2b2d4f3fd2cc72afbd 1033 Gene3D G3DSA:3.30.70.1430 548 646 1.5E-13 T 29-03-2018 CDC59_RS05740 66f8250365719b2b2d4f3fd2cc72afbd 1033 Gene3D G3DSA:3.30.2090.10 180 267 3.2E-13 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS05740 66f8250365719b2b2d4f3fd2cc72afbd 1033 Gene3D G3DSA:1.20.1640.10 282 501 1.2E-42 T 29-03-2018 CDC59_RS05740 66f8250365719b2b2d4f3fd2cc72afbd 1033 Gene3D G3DSA:1.20.1640.10 787 1005 1.3E-34 T 29-03-2018 CDC59_RS05740 66f8250365719b2b2d4f3fd2cc72afbd 1033 SUPERFAMILY SSF82714 182 263 1.83E-12 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS05740 66f8250365719b2b2d4f3fd2cc72afbd 1033 Pfam PF00873 AcrB/AcrD/AcrF family 4 1002 1.5E-219 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS05740 66f8250365719b2b2d4f3fd2cc72afbd 1033 Gene3D G3DSA:3.30.70.1430 40 141 7.7E-20 T 29-03-2018 CDC59_RS05740 66f8250365719b2b2d4f3fd2cc72afbd 1033 SUPERFAMILY SSF82866 291 488 3.14E-44 T 29-03-2018 CDC59_RS05740 66f8250365719b2b2d4f3fd2cc72afbd 1033 SUPERFAMILY SSF82866 782 1003 6.8E-46 T 29-03-2018 CDC59_RS05740 66f8250365719b2b2d4f3fd2cc72afbd 1033 SUPERFAMILY SSF82693 547 644 4.81E-10 T 29-03-2018 CDC59_RS05740 66f8250365719b2b2d4f3fd2cc72afbd 1033 Gene3D G3DSA:3.30.2090.10 694 784 1.9E-13 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CDC59_RS03015 c46e087128e60984ec471f61d39bdaea 339 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 245 309 5.1E-18 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CDC59_RS03015 c46e087128e60984ec471f61d39bdaea 339 Pfam PF00005 ABC transporter 31 193 1.4E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS03015 c46e087128e60984ec471f61d39bdaea 339 SUPERFAMILY SSF52540 39 312 3.44E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS03015 c46e087128e60984ec471f61d39bdaea 339 ProSitePatterns PS00211 ABC transporters family signature. 166 180 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS03015 c46e087128e60984ec471f61d39bdaea 339 SMART SM00382 39 243 6.7E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS03015 c46e087128e60984ec471f61d39bdaea 339 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 243 327 3.9E-23 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CDC59_RS03015 c46e087128e60984ec471f61d39bdaea 339 Gene3D G3DSA:3.40.50.300 7 338 1.3E-69 T 29-03-2018 CDC59_RS04275 99493e3e408c50be0d22665bf4f7a30b 349 Pfam PF01734 Patatin-like phospholipase 11 206 2.8E-15 T 29-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 CDC59_RS04275 99493e3e408c50be0d22665bf4f7a30b 349 Gene3D G3DSA:3.40.1090.10 1 237 3.4E-35 T 29-03-2018 CDC59_RS04275 99493e3e408c50be0d22665bf4f7a30b 349 SUPERFAMILY SSF52151 6 85 2.62E-47 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CDC59_RS04275 99493e3e408c50be0d22665bf4f7a30b 349 SUPERFAMILY SSF52151 118 324 2.62E-47 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CDC59_RS11015 f25e9f730ccc71c1f44a93972ea4ba56 122 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 86 119 2.9E-13 T 29-03-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 CDC59_RS11015 f25e9f730ccc71c1f44a93972ea4ba56 122 SUPERFAMILY SSF57716 86 120 6.7E-9 T 29-03-2018 CDC59_RS19210 91c65b64a124146b0a9d54e5954c7171 174 SMART SM00344 24 133 4.8E-43 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CDC59_RS19210 91c65b64a124146b0a9d54e5954c7171 174 Gene3D G3DSA:3.30.70.920 76 170 2.5E-23 T 29-03-2018 CDC59_RS19210 91c65b64a124146b0a9d54e5954c7171 174 SUPERFAMILY SSF46785 23 82 2.05E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS19210 91c65b64a124146b0a9d54e5954c7171 174 SUPERFAMILY SSF54909 84 173 4.56E-20 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CDC59_RS19210 91c65b64a124146b0a9d54e5954c7171 174 ProSitePatterns PS00519 AsnC-type HTH domain signature. 42 68 - T 29-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site CDC59_RS19210 91c65b64a124146b0a9d54e5954c7171 174 Pfam PF01037 Lrp/AsnC ligand binding domain 90 164 2.8E-20 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CDC59_RS19210 91c65b64a124146b0a9d54e5954c7171 174 Gene3D G3DSA:1.10.10.10 24 75 4.3E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS19210 91c65b64a124146b0a9d54e5954c7171 174 Pfam PF13404 AsnC-type helix-turn-helix domain 24 65 3.4E-16 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CDC59_RS19210 91c65b64a124146b0a9d54e5954c7171 174 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 24 40 2.8E-11 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CDC59_RS19210 91c65b64a124146b0a9d54e5954c7171 174 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 40 51 2.8E-11 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CDC59_RS19210 91c65b64a124146b0a9d54e5954c7171 174 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 51 70 2.8E-11 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CDC59_RS10815 bf1328d320a3550b8d04c926c770117b 470 Gene3D G3DSA:3.30.465.10 95 239 5.8E-35 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CDC59_RS10815 bf1328d320a3550b8d04c926c770117b 470 Gene3D G3DSA:1.10.45.10 430 469 1.4E-14 T 29-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CDC59_RS10815 bf1328d320a3550b8d04c926c770117b 470 Pfam PF01565 FAD binding domain 42 178 7.2E-36 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CDC59_RS10815 bf1328d320a3550b8d04c926c770117b 470 SUPERFAMILY SSF56176 4 219 2.62E-74 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CDC59_RS10815 bf1328d320a3550b8d04c926c770117b 470 Gene3D G3DSA:3.30.43.10 1 94 8.4E-26 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CDC59_RS10815 bf1328d320a3550b8d04c926c770117b 470 Pfam PF02913 FAD linked oxidases, C-terminal domain 219 469 1.2E-49 T 29-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CDC59_RS10815 bf1328d320a3550b8d04c926c770117b 470 SUPERFAMILY SSF55103 222 470 1.64E-57 T 29-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CDC59_RS16875 b959c75d85d57b0d8458a0a64ffa879e 147 SUPERFAMILY SSF54427 11 126 8.6E-24 T 29-03-2018 IPR032710 NTF2-like domain CDC59_RS16875 b959c75d85d57b0d8458a0a64ffa879e 147 Pfam PF12680 SnoaL-like domain 17 114 1.4E-13 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CDC59_RS16875 b959c75d85d57b0d8458a0a64ffa879e 147 Gene3D G3DSA:3.10.450.50 3 145 6.6E-28 T 29-03-2018 CDC59_RS01710 f578c70fb16b666b95883c666cf5df99 192 Gene3D G3DSA:3.30.1360.100 110 183 2.2E-17 T 29-03-2018 IPR023229 Type II secretion system protein M, periplasmic domain CDC59_RS01710 f578c70fb16b666b95883c666cf5df99 192 SUPERFAMILY SSF103054 109 185 1.18E-17 T 29-03-2018 IPR023229 Type II secretion system protein M, periplasmic domain CDC59_RS01710 f578c70fb16b666b95883c666cf5df99 192 Pfam PF04612 Type II secretion system (T2SS), protein M 28 184 2.8E-46 T 29-03-2018 IPR007690 Type II secretion system, protein M GO:0009306 CDC59_RS17440 3544e1a5da622fa606a0f3bd40c648fa 320 Pfam PF09828 Chromate resistance exported protein 185 314 1.3E-44 T 29-03-2018 IPR018634 Chromate resistance exported protein CDC59_RS07095 83d76a732565fdab8f8197050919e852 422 PIRSF PIRSF020818 1 421 5.1E-199 T 29-03-2018 IPR010915 Polyhydroxyalkanoate depolymerase CDC59_RS07095 83d76a732565fdab8f8197050919e852 422 Pfam PF06850 PHB de-polymerase C-terminus 211 412 1.7E-96 T 29-03-2018 IPR009656 PHB de-polymerase, C-terminal CDC59_RS07095 83d76a732565fdab8f8197050919e852 422 Gene3D G3DSA:3.40.50.1820 90 412 9.6E-12 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS07095 83d76a732565fdab8f8197050919e852 422 SUPERFAMILY SSF53474 107 410 1.66E-27 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS07095 83d76a732565fdab8f8197050919e852 422 TIGRFAM TIGR01849 PHB_depoly_PhaZ: polyhydroxyalkanoate depolymerase, intracellular 2 412 9.3E-180 T 29-03-2018 IPR010915 Polyhydroxyalkanoate depolymerase CDC59_RS00215 a69349a403aec0ae9191aff7ccdc54c8 71 Pfam PF13490 Putative zinc-finger 10 43 4.2E-8 T 29-03-2018 IPR027383 Putative zinc-finger CDC59_RS15595 e5ff7b298f41cafeeaea16acabb21b4c 390 Gene3D G3DSA:3.20.20.70 4 382 3.9E-29 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS15595 e5ff7b298f41cafeeaea16acabb21b4c 390 Pfam PF03060 Nitronate monooxygenase 14 374 6.2E-33 T 29-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CDC59_RS15595 e5ff7b298f41cafeeaea16acabb21b4c 390 SUPERFAMILY SSF51412 14 329 4.43E-31 T 29-03-2018 CDC59_RS20090 66022eaefaa4960d3ef3d34233247c02 649 Gene3D G3DSA:3.80.10.10 159 261 1.2E-14 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like CDC59_RS20090 66022eaefaa4960d3ef3d34233247c02 649 SUPERFAMILY SSF52058 173 433 5.95E-44 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like CDC59_RS20090 66022eaefaa4960d3ef3d34233247c02 649 Gene3D G3DSA:3.80.10.10 336 437 1.9E-25 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like CDC59_RS20090 66022eaefaa4960d3ef3d34233247c02 649 Gene3D G3DSA:3.80.10.10 262 335 8.3E-18 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like CDC59_RS08900 d0515c475314cae98b57f51cd753d229 575 SUPERFAMILY SSF52518 380 562 3.04E-57 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CDC59_RS08900 d0515c475314cae98b57f51cd753d229 575 Gene3D G3DSA:3.40.50.970 361 568 2.5E-38 T 29-03-2018 CDC59_RS08900 d0515c475314cae98b57f51cd753d229 575 SUPERFAMILY SSF52467 173 370 3.05E-37 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CDC59_RS08900 d0515c475314cae98b57f51cd753d229 575 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 403 553 6.1E-41 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CDC59_RS08900 d0515c475314cae98b57f51cd753d229 575 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 208 345 1.6E-28 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CDC59_RS08900 d0515c475314cae98b57f51cd753d229 575 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 443 462 - T 29-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CDC59_RS08900 d0515c475314cae98b57f51cd753d229 575 SUPERFAMILY SSF52518 18 200 2.08E-53 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CDC59_RS08900 d0515c475314cae98b57f51cd753d229 575 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 21 185 3.0E-52 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CDC59_RS08900 d0515c475314cae98b57f51cd753d229 575 Gene3D G3DSA:3.40.50.1220 203 360 5.6E-35 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CDC59_RS08900 d0515c475314cae98b57f51cd753d229 575 Gene3D G3DSA:3.40.50.970 14 202 4.1E-53 T 29-03-2018 CDC59_RS10015 ab60fbe2a93e1a0979694c294c220b16 186 Pfam PF04279 Intracellular septation protein A 1 175 3.9E-72 T 29-03-2018 IPR006008 Intracellular septation protein A GO:0016021 CDC59_RS10015 ab60fbe2a93e1a0979694c294c220b16 186 TIGRFAM TIGR00997 ispZ: intracellular septation protein A 1 175 3.6E-62 T 29-03-2018 IPR006008 Intracellular septation protein A GO:0016021 CDC59_RS10015 ab60fbe2a93e1a0979694c294c220b16 186 Hamap MF_00189 Probable intracellular septation protein A [yciB]. 1 176 19.629 T 29-03-2018 IPR006008 Intracellular septation protein A GO:0016021 CDC59_RS21660 0dc6f901a3672cf8de53bd86dc3da1be 228 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 24 217 4.6E-23 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS21660 0dc6f901a3672cf8de53bd86dc3da1be 228 Gene3D G3DSA:1.10.3720.10 1 222 6.8E-42 T 29-03-2018 CDC59_RS21660 0dc6f901a3672cf8de53bd86dc3da1be 228 SUPERFAMILY SSF161098 4 215 1.7E-54 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS21660 0dc6f901a3672cf8de53bd86dc3da1be 228 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 10 213 4.9E-75 T 29-03-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 CDC59_RS03570 d6a816675bd423dd69e79f93bf51bdd4 263 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 1 123 3.5E-37 T 29-03-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CDC59_RS03570 d6a816675bd423dd69e79f93bf51bdd4 263 Gene3D G3DSA:3.40.50.720 1 119 7.4E-29 T 29-03-2018 CDC59_RS03570 d6a816675bd423dd69e79f93bf51bdd4 263 PIRSF PIRSF000161 1 263 6.5E-82 T 29-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CDC59_RS03570 d6a816675bd423dd69e79f93bf51bdd4 263 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 1 262 4.9E-90 T 29-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CDC59_RS03570 d6a816675bd423dd69e79f93bf51bdd4 263 Gene3D G3DSA:3.30.360.10 124 232 1.3E-35 T 29-03-2018 CDC59_RS03570 d6a816675bd423dd69e79f93bf51bdd4 263 SUPERFAMILY SSF51735 234 263 6.63E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS03570 d6a816675bd423dd69e79f93bf51bdd4 263 SUPERFAMILY SSF51735 1 124 6.63E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS03570 d6a816675bd423dd69e79f93bf51bdd4 263 SUPERFAMILY SSF55347 125 234 1.16E-35 T 29-03-2018 CDC59_RS03570 d6a816675bd423dd69e79f93bf51bdd4 263 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 148 165 - T 29-03-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CDC59_RS03570 d6a816675bd423dd69e79f93bf51bdd4 263 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 126 261 1.2E-42 T 29-03-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CDC59_RS03570 d6a816675bd423dd69e79f93bf51bdd4 263 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 1 262 35.01 T 29-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CDC59_RS12830 4988682fa15122a72925ca4501a77de4 338 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 38 318 2.6E-21 T 29-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CDC59_RS12305 c3e1d8aa23033b6e5229eab052e147ea 219 Gene3D G3DSA:3.40.50.300 1 72 4.2E-15 T 29-03-2018 CDC59_RS12305 c3e1d8aa23033b6e5229eab052e147ea 219 Gene3D G3DSA:3.40.50.300 73 215 1.6E-15 T 29-03-2018 CDC59_RS12305 c3e1d8aa23033b6e5229eab052e147ea 219 PIRSF PIRSF009320 1 202 8.2E-24 T 29-03-2018 CDC59_RS12305 c3e1d8aa23033b6e5229eab052e147ea 219 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 182 9.7E-15 T 29-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CDC59_RS12305 c3e1d8aa23033b6e5229eab052e147ea 219 SUPERFAMILY SSF52540 1 205 5.89E-32 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS20560 05903c6af1fd9b87bdf965e1fc0b4b12 174 Pfam PF13671 AAA domain 2 119 3.1E-10 T 29-03-2018 CDC59_RS20560 05903c6af1fd9b87bdf965e1fc0b4b12 174 Gene3D G3DSA:3.40.50.300 1 166 3.7E-17 T 29-03-2018 CDC59_RS20560 05903c6af1fd9b87bdf965e1fc0b4b12 174 SUPERFAMILY SSF52540 1 164 2.52E-19 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS14970 5b64206d6c18f414da1e7e6c8b13ed3f 229 Gene3D G3DSA:1.10.150.240 41 85 6.4E-17 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CDC59_RS14970 5b64206d6c18f414da1e7e6c8b13ed3f 229 Gene3D G3DSA:3.40.50.1000 11 40 0.036 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS14970 5b64206d6c18f414da1e7e6c8b13ed3f 229 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 87 198 1.7E-14 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDC59_RS14970 5b64206d6c18f414da1e7e6c8b13ed3f 229 Pfam PF13419 Haloacid dehalogenase-like hydrolase 17 199 2.7E-26 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS14970 5b64206d6c18f414da1e7e6c8b13ed3f 229 SUPERFAMILY SSF56784 13 228 4.79E-54 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS14970 5b64206d6c18f414da1e7e6c8b13ed3f 229 Gene3D G3DSA:3.40.50.1000 86 229 2.0E-28 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS03805 ba7e8f715ec064e556dbb2f17e977027 302 Pfam PF00701 Dihydrodipicolinate synthetase family 2 288 2.9E-47 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CDC59_RS03805 ba7e8f715ec064e556dbb2f17e977027 302 Gene3D G3DSA:3.20.20.70 1 293 4.6E-75 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS03805 ba7e8f715ec064e556dbb2f17e977027 302 PIRSF PIRSF001365 1 301 1.3E-74 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CDC59_RS03805 ba7e8f715ec064e556dbb2f17e977027 302 SMART SM01130 2 291 7.6E-79 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CDC59_RS03805 ba7e8f715ec064e556dbb2f17e977027 302 PRINTS PR00146 Dihydrodipicolinate synthase signature 72 90 3.8E-13 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CDC59_RS03805 ba7e8f715ec064e556dbb2f17e977027 302 PRINTS PR00146 Dihydrodipicolinate synthase signature 129 146 3.8E-13 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CDC59_RS03805 ba7e8f715ec064e556dbb2f17e977027 302 PRINTS PR00146 Dihydrodipicolinate synthase signature 36 57 3.8E-13 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CDC59_RS03805 ba7e8f715ec064e556dbb2f17e977027 302 SUPERFAMILY SSF51569 1 290 9.11E-76 T 29-03-2018 CDC59_RS00115 b1e585e767ca8acccd54218e7a93a825 154 Pfam PF12276 Protein of unknown function (DUF3617) 4 153 4.4E-24 T 29-03-2018 IPR022061 Protein of unknown function DUF3617 CDC59_RS19020 daf404af73192ad5944146fb7d5aa898 437 Gene3D G3DSA:1.20.1250.20 14 214 4.0E-10 T 29-03-2018 CDC59_RS19020 daf404af73192ad5944146fb7d5aa898 437 Gene3D G3DSA:1.20.1250.20 219 421 7.2E-19 T 29-03-2018 CDC59_RS19020 daf404af73192ad5944146fb7d5aa898 437 SUPERFAMILY SSF103473 19 409 2.22E-26 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS19020 daf404af73192ad5944146fb7d5aa898 437 Pfam PF07690 Major Facilitator Superfamily 45 366 4.3E-13 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDC59_RS18450 910455bf0c371073e4ef9daac245433e 220 Pfam PF11445 Protein of unknown function (DUF2894) 12 195 2.9E-69 T 29-03-2018 IPR021549 Protein of unknown function DUF2894 CDC59_RS23785 671a58dc78943e3b7a1fc17b03f92b4b 434 Pfam PF02321 Outer membrane efflux protein 36 221 1.4E-15 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CDC59_RS23785 671a58dc78943e3b7a1fc17b03f92b4b 434 Pfam PF02321 Outer membrane efflux protein 252 418 1.5E-14 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CDC59_RS23785 671a58dc78943e3b7a1fc17b03f92b4b 434 SUPERFAMILY SSF56954 6 418 1.57E-46 T 29-03-2018 CDC59_RS23785 671a58dc78943e3b7a1fc17b03f92b4b 434 Gene3D G3DSA:1.20.1600.10 23 419 1.4E-38 T 29-03-2018 CDC59_RS08595 850870c9d5072aba315739ed5bd1fb62 170 SMART SM00347 45 145 8.4E-25 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS08595 850870c9d5072aba315739ed5bd1fb62 170 Pfam PF01047 MarR family 53 110 2.0E-16 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS08595 850870c9d5072aba315739ed5bd1fb62 170 Gene3D G3DSA:1.10.10.10 17 159 4.8E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS08595 850870c9d5072aba315739ed5bd1fb62 170 SUPERFAMILY SSF46785 23 158 5.1E-35 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS08595 850870c9d5072aba315739ed5bd1fb62 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 85 4.6E-14 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS08595 850870c9d5072aba315739ed5bd1fb62 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 105 121 4.6E-14 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS08595 850870c9d5072aba315739ed5bd1fb62 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 101 4.6E-14 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS08595 850870c9d5072aba315739ed5bd1fb62 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 135 155 4.6E-14 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS08595 850870c9d5072aba315739ed5bd1fb62 170 ProSitePatterns PS01117 MarR-type HTH domain signature. 84 118 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CDC59_RS18510 2dd3a29add11c06c0743361c3a1e3aa1 144 Gene3D G3DSA:2.60.40.10 25 136 2.7E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold CDC59_RS18510 2dd3a29add11c06c0743361c3a1e3aa1 144 Pfam PF07705 CARDB 50 131 9.0E-7 T 29-03-2018 IPR011635 CARDB domain CDC59_RS22095 92fd571a895f49d7aade0b280c57e5e8 230 Pfam PF12728 Helix-turn-helix domain 126 175 2.2E-7 T 29-03-2018 CDC59_RS22095 92fd571a895f49d7aade0b280c57e5e8 230 Gene3D G3DSA:1.10.10.10 126 185 3.9E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS22095 92fd571a895f49d7aade0b280c57e5e8 230 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 126 175 7.7E-11 T 29-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 CDC59_RS21485 b23e525a8ebae3ab7f7b8117e71fd795 159 Pfam PF07811 TadE-like protein 24 66 2.5E-13 T 29-03-2018 IPR012495 TadE-like CDC59_RS05155 ec66ea6b040b3ae8d721b06af665009d 274 Gene3D G3DSA:2.60.40.760 177 253 7.6E-18 T 29-03-2018 IPR007117 Expansin, cellulose-binding-like domain CDC59_RS05155 ec66ea6b040b3ae8d721b06af665009d 274 SUPERFAMILY SSF50685 59 169 8.37E-18 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CDC59_RS05155 ec66ea6b040b3ae8d721b06af665009d 274 Gene3D G3DSA:2.40.40.10 49 176 5.4E-15 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CDC59_RS05155 ec66ea6b040b3ae8d721b06af665009d 274 SUPERFAMILY SSF49590 167 239 2.35E-10 T 29-03-2018 IPR007117 Expansin, cellulose-binding-like domain CDC59_RS18575 d394f19fca953a7d927984709339d8b7 153 SUPERFAMILY SSF49785 56 108 2.2E-9 T 29-03-2018 IPR008979 Galactose-binding domain-like CDC59_RS18575 d394f19fca953a7d927984709339d8b7 153 Gene3D G3DSA:2.60.120.260 28 141 4.6E-11 T 29-03-2018 IPR008979 Galactose-binding domain-like CDC59_RS13875 396e306e084bfffe901f443d36769ef1 254 Gene3D G3DSA:3.90.226.10 2 210 3.3E-58 T 29-03-2018 CDC59_RS13875 396e306e084bfffe901f443d36769ef1 254 Gene3D G3DSA:1.10.12.10 211 245 3.1E-16 T 29-03-2018 IPR014748 Crontonase, C-terminal CDC59_RS13875 396e306e084bfffe901f443d36769ef1 254 Pfam PF00378 Enoyl-CoA hydratase/isomerase 7 251 3.9E-52 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CDC59_RS13875 396e306e084bfffe901f443d36769ef1 254 SUPERFAMILY SSF52096 3 252 6.14E-74 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CDC59_RS10575 72a7a302c6b1104c2e570c26650349e9 317 Pfam PF01263 Aldose 1-epimerase 25 308 7.7E-21 T 29-03-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 CDC59_RS10575 72a7a302c6b1104c2e570c26650349e9 317 Gene3D G3DSA:2.70.98.10 12 312 1.2E-52 T 29-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CDC59_RS10575 72a7a302c6b1104c2e570c26650349e9 317 SUPERFAMILY SSF74650 6 311 4.65E-46 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CDC59_RS01670 b79720a947ac98dabe5fbb2e0ea073e3 57 PRINTS PR00812 Bacterial general secretion pathway protein F signature 21 35 1.1E-8 T 29-03-2018 IPR003004 GspF/PilC family CDC59_RS01670 b79720a947ac98dabe5fbb2e0ea073e3 57 PRINTS PR00812 Bacterial general secretion pathway protein F signature 37 56 1.1E-8 T 29-03-2018 IPR003004 GspF/PilC family CDC59_RS03195 7584ce8c975451e83829eb9518906623 153 PRINTS PR00502 NUDIX hydrolase family signature 54 68 3.5E-7 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CDC59_RS03195 7584ce8c975451e83829eb9518906623 153 PRINTS PR00502 NUDIX hydrolase family signature 68 83 3.5E-7 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CDC59_RS03195 7584ce8c975451e83829eb9518906623 153 ProSitePatterns PS00893 Nudix box signature. 59 80 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CDC59_RS03195 7584ce8c975451e83829eb9518906623 153 Pfam PF00293 NUDIX domain 27 125 1.5E-17 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CDC59_RS03195 7584ce8c975451e83829eb9518906623 153 SUPERFAMILY SSF55811 23 137 1.9E-33 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CDC59_RS03195 7584ce8c975451e83829eb9518906623 153 Gene3D G3DSA:3.90.79.10 19 149 1.2E-26 T 29-03-2018 CDC59_RS06395 dcd880dac79bd2afca3c143c743ce1a8 318 Pfam PF06166 Protein of unknown function (DUF979) 6 316 8.8E-130 T 29-03-2018 IPR009323 Protein of unknown function DUF979 CDC59_RS20225 d5fcd86c6056db72c6016542d1f4070e 297 TIGRFAM TIGR02499 HrpE_YscL_not: type III secretion apparatus protein, HrpE/YscL family 35 206 6.6E-38 T 29-03-2018 IPR012842 Type III secretion system HrpE/YscL CDC59_RS20225 d5fcd86c6056db72c6016542d1f4070e 297 Pfam PF02108 Flagellar assembly protein FliH 90 213 5.4E-11 T 29-03-2018 IPR018035 Flagellar assembly protein FliH/Type III secretion system HrpE CDC59_RS08905 bba5a36a17b27fe2fe97c45e32f2c1c8 168 Gene3D G3DSA:3.50.30.40 4 168 4.6E-44 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CDC59_RS08905 bba5a36a17b27fe2fe97c45e32f2c1c8 168 SUPERFAMILY SSF89562 7 166 2.88E-45 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CDC59_RS08905 bba5a36a17b27fe2fe97c45e32f2c1c8 168 Pfam PF03737 Aldolase/RraA 9 161 3.2E-42 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CDC59_RS08905 bba5a36a17b27fe2fe97c45e32f2c1c8 168 TIGRFAM TIGR01935 NOT-MenG: RraA family 8 161 1.6E-67 T 29-03-2018 IPR010203 Regulator of ribonuclease activity A GO:0008428|GO:0051252 CDC59_RS21490 b2ad4b4f73011d63d190f64530a85bbc 183 Pfam PF01478 Type IV leader peptidase family 14 116 2.6E-15 T 29-03-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 CDC59_RS04640 81e22232e7e1ee4d1b786ebdfe4bbb29 217 Gene3D G3DSA:2.40.30.20 1 91 3.2E-17 T 29-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS04640 81e22232e7e1ee4d1b786ebdfe4bbb29 217 Gene3D G3DSA:2.40.30.20 96 197 7.1E-32 T 29-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS04640 81e22232e7e1ee4d1b786ebdfe4bbb29 217 SUPERFAMILY SSF63380 96 204 2.98E-31 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CDC59_RS04640 81e22232e7e1ee4d1b786ebdfe4bbb29 217 SUPERFAMILY SSF63380 1 92 1.28E-15 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CDC59_RS04640 81e22232e7e1ee4d1b786ebdfe4bbb29 217 PIRSF PIRSF000498 1 212 7.1E-69 T 29-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CDC59_RS04640 81e22232e7e1ee4d1b786ebdfe4bbb29 217 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 203 6.2E-51 T 29-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CDC59_RS04640 81e22232e7e1ee4d1b786ebdfe4bbb29 217 Pfam PF00677 Lumazine binding domain 3 88 5.7E-13 T 29-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CDC59_RS04640 81e22232e7e1ee4d1b786ebdfe4bbb29 217 Pfam PF00677 Lumazine binding domain 102 190 5.2E-23 T 29-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CDC59_RS11795 1fdced1141ba20daf7c977f95f5d22e8 417 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 43 54 - T 29-03-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS11795 1fdced1141ba20daf7c977f95f5d22e8 417 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 1 417 50.301 T 29-03-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS11795 1fdced1141ba20daf7c977f95f5d22e8 417 SUPERFAMILY SSF56762 16 417 3.53E-138 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS11795 1fdced1141ba20daf7c977f95f5d22e8 417 Gene3D G3DSA:1.10.645.10 233 409 3.4E-45 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS11795 1fdced1141ba20daf7c977f95f5d22e8 417 Gene3D G3DSA:1.10.645.10 2 232 3.5E-63 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS11795 1fdced1141ba20daf7c977f95f5d22e8 417 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 120 417 2.8E-123 T 29-03-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS11795 1fdced1141ba20daf7c977f95f5d22e8 417 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 6 417 5.2E-188 T 29-03-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS14930 eb316836a9fa8068d2b5c71e28ebcb2e 226 Gene3D G3DSA:3.40.1050.10 1 219 6.7E-70 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CDC59_RS14930 eb316836a9fa8068d2b5c71e28ebcb2e 226 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 43 50 - T 29-03-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CDC59_RS14930 eb316836a9fa8068d2b5c71e28ebcb2e 226 SMART SM00947 31 194 5.3E-66 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CDC59_RS14930 eb316836a9fa8068d2b5c71e28ebcb2e 226 SUPERFAMILY SSF53056 4 212 3.53E-73 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CDC59_RS14930 eb316836a9fa8068d2b5c71e28ebcb2e 226 Pfam PF00484 Carbonic anhydrase 38 189 4.4E-50 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CDC59_RS01480 0554f2160eb4d55775bc486224eeee32 263 Gene3D G3DSA:3.40.50.720 1 258 1.7E-53 T 29-03-2018 CDC59_RS01480 0554f2160eb4d55775bc486224eeee32 263 SUPERFAMILY SSF51735 6 255 4.14E-53 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS01480 0554f2160eb4d55775bc486224eeee32 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 254 5.5E-35 T 29-03-2018 CDC59_RS01480 0554f2160eb4d55775bc486224eeee32 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 1.3E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS01480 0554f2160eb4d55775bc486224eeee32 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 1.3E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS01480 0554f2160eb4d55775bc486224eeee32 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 1.3E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS01480 0554f2160eb4d55775bc486224eeee32 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.3E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS01480 0554f2160eb4d55775bc486224eeee32 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.3E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS01480 0554f2160eb4d55775bc486224eeee32 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 1.3E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS04245 4b5acee3cbe5f61c1ce8ae1fa343d551 530 PRINTS PR01806 Virulence factor MviN signature 427 444 7.8E-78 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CDC59_RS04245 4b5acee3cbe5f61c1ce8ae1fa343d551 530 PRINTS PR01806 Virulence factor MviN signature 46 65 7.8E-78 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CDC59_RS04245 4b5acee3cbe5f61c1ce8ae1fa343d551 530 PRINTS PR01806 Virulence factor MviN signature 147 171 7.8E-78 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CDC59_RS04245 4b5acee3cbe5f61c1ce8ae1fa343d551 530 PRINTS PR01806 Virulence factor MviN signature 277 303 7.8E-78 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CDC59_RS04245 4b5acee3cbe5f61c1ce8ae1fa343d551 530 PRINTS PR01806 Virulence factor MviN signature 375 394 7.8E-78 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CDC59_RS04245 4b5acee3cbe5f61c1ce8ae1fa343d551 530 PRINTS PR01806 Virulence factor MviN signature 171 192 7.8E-78 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CDC59_RS04245 4b5acee3cbe5f61c1ce8ae1fa343d551 530 PRINTS PR01806 Virulence factor MviN signature 65 81 7.8E-78 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CDC59_RS04245 4b5acee3cbe5f61c1ce8ae1fa343d551 530 Pfam PF03023 MviN-like protein 41 487 5.9E-135 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CDC59_RS04245 4b5acee3cbe5f61c1ce8ae1fa343d551 530 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 16 522 4.2E-139 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CDC59_RS04245 4b5acee3cbe5f61c1ce8ae1fa343d551 530 Hamap MF_02078 Probable lipid II flippase MurJ [murJ]. 16 485 19.796 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CDC59_RS04245 4b5acee3cbe5f61c1ce8ae1fa343d551 530 PIRSF PIRSF002869 11 530 3.3E-154 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CDC59_RS05655 4290d219f2e2eaa00f71db81f4930a58 437 Pfam PF05707 Zonular occludens toxin (Zot) 1 191 1.1E-26 T 29-03-2018 IPR008900 Zona occludens toxin CDC59_RS05655 4290d219f2e2eaa00f71db81f4930a58 437 Gene3D G3DSA:3.40.50.300 2 195 3.6E-11 T 29-03-2018 CDC59_RS09955 d7b6f85b268028dd9524f7cbbb49d14c 143 Pfam PF13328 HD domain 6 88 3.1E-10 T 29-03-2018 IPR003607 HD/PDEase domain CDC59_RS09955 d7b6f85b268028dd9524f7cbbb49d14c 143 SUPERFAMILY SSF109604 3 141 6.8E-23 T 29-03-2018 CDC59_RS19685 1372f89c5aa75ca9747f94752581f215 371 SUPERFAMILY SSF103473 77 136 1.83E-5 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS19685 1372f89c5aa75ca9747f94752581f215 371 Gene3D G3DSA:1.20.1250.20 63 207 9.6E-6 T 29-03-2018 CDC59_RS10840 b80acb3efbc1d8542ac45bf06ac9d510 908 Gene3D G3DSA:3.40.50.300 6 401 5.4E-10 T 29-03-2018 CDC59_RS10840 b80acb3efbc1d8542ac45bf06ac9d510 908 SUPERFAMILY SSF52540 23 93 6.29E-5 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS10840 b80acb3efbc1d8542ac45bf06ac9d510 908 Gene3D G3DSA:1.20.5.50 657 747 0.029 T 29-03-2018 CDC59_RS01685 149180631fcf2db387e8932021be8fa5 403 PRINTS PR00812 Bacterial general secretion pathway protein F signature 367 381 3.8E-27 T 29-03-2018 IPR003004 GspF/PilC family CDC59_RS01685 149180631fcf2db387e8932021be8fa5 403 PRINTS PR00812 Bacterial general secretion pathway protein F signature 65 77 3.8E-27 T 29-03-2018 IPR003004 GspF/PilC family CDC59_RS01685 149180631fcf2db387e8932021be8fa5 403 PRINTS PR00812 Bacterial general secretion pathway protein F signature 383 402 3.8E-27 T 29-03-2018 IPR003004 GspF/PilC family CDC59_RS01685 149180631fcf2db387e8932021be8fa5 403 PRINTS PR00812 Bacterial general secretion pathway protein F signature 164 192 3.8E-27 T 29-03-2018 IPR003004 GspF/PilC family CDC59_RS01685 149180631fcf2db387e8932021be8fa5 403 Pfam PF00482 Type II secretion system (T2SS), protein F 272 394 6.3E-27 T 29-03-2018 IPR018076 Type II secretion system F domain CDC59_RS01685 149180631fcf2db387e8932021be8fa5 403 Pfam PF00482 Type II secretion system (T2SS), protein F 70 192 1.8E-32 T 29-03-2018 IPR018076 Type II secretion system F domain CDC59_RS01685 149180631fcf2db387e8932021be8fa5 403 TIGRFAM TIGR02120 GspF: type II secretion system protein F 4 402 2.4E-169 T 29-03-2018 IPR011850 General secretion pathway protein F GO:0008565|GO:0015627|GO:0015628 CDC59_RS13820 003ed18bb9f052cec332c28d008dfb9d 432 SUPERFAMILY SSF82544 8 431 9.68E-136 T 29-03-2018 CDC59_RS13820 003ed18bb9f052cec332c28d008dfb9d 432 Pfam PF13660 Domain of unknown function (DUF4147) 13 234 1.6E-75 T 29-03-2018 IPR025286 MOFRL-associated domain Reactome: R-HSA-70350 CDC59_RS13820 003ed18bb9f052cec332c28d008dfb9d 432 Gene3D G3DSA:3.40.1480.10 252 432 1.1E-59 T 29-03-2018 IPR007835 MOFRL domain Reactome: R-HSA-70350 CDC59_RS13820 003ed18bb9f052cec332c28d008dfb9d 432 Pfam PF05161 MOFRL family 317 425 2.7E-33 T 29-03-2018 IPR007835 MOFRL domain Reactome: R-HSA-70350 CDC59_RS13820 003ed18bb9f052cec332c28d008dfb9d 432 Gene3D G3DSA:3.40.50.10180 17 251 7.7E-82 T 29-03-2018 CDC59_RS02475 1bbd042f72b12e0ee043f1eace789566 713 Pfam PF00263 Bacterial type II and III secretion system protein 552 706 4.9E-50 T 29-03-2018 IPR004846 Type II/III secretion system GO:0009306 CDC59_RS02475 1bbd042f72b12e0ee043f1eace789566 713 Pfam PF03958 Bacterial type II/III secretion system short domain 390 462 4.0E-11 T 29-03-2018 IPR005644 NolW-like CDC59_RS02475 1bbd042f72b12e0ee043f1eace789566 713 ProSitePatterns PS00875 Bacterial type II secretion system protein D signature. 652 685 - T 29-03-2018 IPR004845 Type II secretion system GspD, conserved site GO:0008565 CDC59_RS02475 1bbd042f72b12e0ee043f1eace789566 713 TIGRFAM TIGR02515 IV_pilus_PilQ: type IV pilus secretin PilQ 291 706 3.8E-156 T 29-03-2018 IPR013355 Type IV pilus secretin PilQ CDC59_RS02475 1bbd042f72b12e0ee043f1eace789566 713 Pfam PF11741 AMIN domain 65 145 5.9E-7 T 29-03-2018 IPR021731 AMIN domain CDC59_RS02475 1bbd042f72b12e0ee043f1eace789566 713 Pfam PF07660 Secretin and TonB N terminus short domain 318 363 1.8E-8 T 29-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 CDC59_RS02475 1bbd042f72b12e0ee043f1eace789566 713 PRINTS PR00811 Bacterial general secretion pathway protein D signature 694 708 3.7E-22 T 29-03-2018 IPR001775 GspD/PilQ family CDC59_RS02475 1bbd042f72b12e0ee043f1eace789566 713 PRINTS PR00811 Bacterial general secretion pathway protein D signature 671 689 3.7E-22 T 29-03-2018 IPR001775 GspD/PilQ family CDC59_RS02475 1bbd042f72b12e0ee043f1eace789566 713 PRINTS PR00811 Bacterial general secretion pathway protein D signature 462 472 3.7E-22 T 29-03-2018 IPR001775 GspD/PilQ family CDC59_RS02475 1bbd042f72b12e0ee043f1eace789566 713 PRINTS PR00811 Bacterial general secretion pathway protein D signature 548 572 3.7E-22 T 29-03-2018 IPR001775 GspD/PilQ family CDC59_RS02475 1bbd042f72b12e0ee043f1eace789566 713 SMART SM00965 316 364 2.1E-9 T 29-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 CDC59_RS20235 8671803ac3ad3b03c345ee4125ee3e40 166 TIGRFAM TIGR02559 HrpB7: type III secretion protein HrpB7 5 161 1.6E-51 T 29-03-2018 IPR013392 Type III secretion protein HrpB7 CDC59_RS20235 8671803ac3ad3b03c345ee4125ee3e40 166 Gene3D G3DSA:1.10.287.620 3 161 1.3E-5 T 29-03-2018 CDC59_RS20235 8671803ac3ad3b03c345ee4125ee3e40 166 Pfam PF09486 Bacterial type III secretion protein (HrpB7) 5 160 4.0E-41 T 29-03-2018 IPR013392 Type III secretion protein HrpB7 CDC59_RS16720 5bc759ee278bc5cbf447799623d3ae91 454 Pfam PF01554 MatE 274 405 3.1E-10 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CDC59_RS16720 5bc759ee278bc5cbf447799623d3ae91 454 Pfam PF01554 MatE 27 183 2.4E-24 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CDC59_RS16720 5bc759ee278bc5cbf447799623d3ae91 454 TIGRFAM TIGR00797 matE: MATE efflux family protein 27 424 1.7E-65 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CDC59_RS20660 815e3b581f597c30f077e37bdc1b6d2c 188 Pfam PF00578 AhpC/TSA family 48 162 1.1E-16 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CDC59_RS20660 815e3b581f597c30f077e37bdc1b6d2c 188 SUPERFAMILY SSF52833 45 187 5.23E-28 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS20660 815e3b581f597c30f077e37bdc1b6d2c 188 Gene3D G3DSA:3.40.30.10 39 186 5.5E-25 T 29-03-2018 CDC59_RS20660 815e3b581f597c30f077e37bdc1b6d2c 188 ProSitePatterns PS00194 Thioredoxin family active site. 76 94 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CDC59_RS12795 c12f0b99975d64bded1735fa52bf0a85 295 SUPERFAMILY SSF55486 58 224 8.7E-5 T 29-03-2018 CDC59_RS12795 c12f0b99975d64bded1735fa52bf0a85 295 Pfam PF04228 Putative neutral zinc metallopeptidase 2 289 6.6E-121 T 29-03-2018 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative CDC59_RS22825 3bb78506d74a19e9dd5a1bf0f2e0623c 337 SUPERFAMILY SSF103088 217 311 2.22E-8 T 29-03-2018 IPR006665 OmpA-like domain CDC59_RS22825 3bb78506d74a19e9dd5a1bf0f2e0623c 337 Gene3D G3DSA:3.30.1330.60 184 331 4.8E-8 T 29-03-2018 IPR006665 OmpA-like domain CDC59_RS22825 3bb78506d74a19e9dd5a1bf0f2e0623c 337 Pfam PF00691 OmpA family 218 306 8.8E-6 T 29-03-2018 IPR006665 OmpA-like domain CDC59_RS14375 e7521ddc2bae3f4e640f195a731b5988 420 Pfam PF13379 NMT1-like family 45 294 2.7E-104 T 29-03-2018 CDC59_RS14375 e7521ddc2bae3f4e640f195a731b5988 420 SUPERFAMILY SSF53850 48 282 6.92E-30 T 29-03-2018 CDC59_RS14375 e7521ddc2bae3f4e640f195a731b5988 420 Gene3D G3DSA:3.40.190.10 46 159 1.1E-8 T 29-03-2018 CDC59_RS14375 e7521ddc2bae3f4e640f195a731b5988 420 Gene3D G3DSA:3.40.190.10 160 376 3.5E-39 T 29-03-2018 CDC59_RS17710 090a77b65ff17549a62e7ceeeaf8f754 484 Pfam PF00171 Aldehyde dehydrogenase family 19 473 2.3E-148 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CDC59_RS17710 090a77b65ff17549a62e7ceeeaf8f754 484 SUPERFAMILY SSF53720 3 479 9.03E-151 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CDC59_RS17710 090a77b65ff17549a62e7ceeeaf8f754 484 Gene3D G3DSA:3.40.309.10 269 457 1.9E-67 T 29-03-2018 CDC59_RS17710 090a77b65ff17549a62e7ceeeaf8f754 484 Gene3D G3DSA:3.40.605.10 1 268 6.8E-84 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CDC59_RS17710 090a77b65ff17549a62e7ceeeaf8f754 484 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 250 257 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CDC59_RS09245 6d2bbf3b94e8e9954ad6a140749d9fe1 279 Pfam PF03618 Kinase/pyrophosphorylase 13 269 8.3E-81 T 29-03-2018 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 CDC59_RS09245 6d2bbf3b94e8e9954ad6a140749d9fe1 279 Hamap MF_01062 Phosphoenolpyruvate synthase regulatory protein [ppsR]. 10 278 75.316 T 29-03-2018 IPR026530 Phosphoenolpyruvate synthase regulatory protein CDC59_RS09245 6d2bbf3b94e8e9954ad6a140749d9fe1 279 Gene3D G3DSA:3.40.50.300 39 277 9.6E-4 T 29-03-2018 CDC59_RS21550 1bbce068bae2c0e4766c11723bebd61b 341 Pfam PF16363 GDP-mannose 4,6 dehydratase 6 325 1.6E-53 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS21550 1bbce068bae2c0e4766c11723bebd61b 341 Gene3D G3DSA:3.40.50.720 1 208 1.2E-37 T 29-03-2018 CDC59_RS21550 1bbce068bae2c0e4766c11723bebd61b 341 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 5 335 1.1E-130 T 29-03-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-70370 CDC59_RS21550 1bbce068bae2c0e4766c11723bebd61b 341 SUPERFAMILY SSF51735 1 336 2.03E-92 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS21550 1bbce068bae2c0e4766c11723bebd61b 341 Gene3D G3DSA:3.90.25.10 209 256 5.1E-10 T 29-03-2018 CDC59_RS21550 1bbce068bae2c0e4766c11723bebd61b 341 Gene3D G3DSA:3.90.25.10 258 338 2.0E-23 T 29-03-2018 CDC59_RS13615 d05bad6aad5aaa6d5139417f50818099 199 Pfam PF13242 HAD-hyrolase-like 103 172 2.3E-9 T 29-03-2018 CDC59_RS13615 d05bad6aad5aaa6d5139417f50818099 199 SUPERFAMILY SSF56784 5 179 1.36E-43 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS13615 d05bad6aad5aaa6d5139417f50818099 199 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 6 144 5.6E-35 T 29-03-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 CDC59_RS13615 d05bad6aad5aaa6d5139417f50818099 199 Gene3D G3DSA:3.40.50.1000 6 183 2.2E-30 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS13615 d05bad6aad5aaa6d5139417f50818099 199 PIRSF PIRSF004682 1 182 4.0E-52 T 29-03-2018 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 CDC59_RS13615 d05bad6aad5aaa6d5139417f50818099 199 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 7 146 1.7E-45 T 29-03-2018 IPR006543 Histidinol-phosphate phosphatase GO:0016791 CDC59_RS12025 3de123f1e46b0657c9c535881e9677bf 290 SUPERFAMILY SSF81301 10 99 1.96E-6 T 29-03-2018 CDC59_RS12025 3de123f1e46b0657c9c535881e9677bf 290 Gene3D G3DSA:3.30.460.10 19 146 5.8E-7 T 29-03-2018 CDC59_RS12025 3de123f1e46b0657c9c535881e9677bf 290 Gene3D G3DSA:1.10.1410.20 147 209 0.0012 T 29-03-2018 CDC59_RS05430 fb49122a49bb23d47b24277125649440 227 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 94 185 8.8E-11 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDC59_RS05430 fb49122a49bb23d47b24277125649440 227 Pfam PF13419 Haloacid dehalogenase-like hydrolase 11 190 1.0E-30 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS05430 fb49122a49bb23d47b24277125649440 227 SUPERFAMILY SSF56784 10 221 6.51E-55 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS05430 fb49122a49bb23d47b24277125649440 227 Gene3D G3DSA:1.10.150.240 23 78 7.2E-13 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CDC59_RS05430 fb49122a49bb23d47b24277125649440 227 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 93 189 9.2E-9 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDC59_RS05430 fb49122a49bb23d47b24277125649440 227 TIGRFAM TIGR01449 PGP_bact: phosphoglycolate phosphatase, bacterial 11 221 3.8E-54 T 29-03-2018 IPR006346 2-phosphoglycolate phosphatase, prokaryotic GO:0008967|GO:0046295 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 CDC59_RS05430 fb49122a49bb23d47b24277125649440 227 Gene3D G3DSA:3.40.50.1000 79 227 5.7E-31 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS09055 206625325a3842537fbcdb92749acc04 338 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 56 334 1.1E-29 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 CDC59_RS09055 206625325a3842537fbcdb92749acc04 338 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 28 238 2.1E-12 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CDC59_RS09055 206625325a3842537fbcdb92749acc04 338 Gene3D G3DSA:2.40.50.100 139 302 4.0E-5 T 29-03-2018 CDC59_RS09055 206625325a3842537fbcdb92749acc04 338 Gene3D G3DSA:3.90.1170.30 2 90 2.9E-4 T 29-03-2018 CDC59_RS09055 206625325a3842537fbcdb92749acc04 338 SUPERFAMILY SSF111369 57 259 8.5E-13 T 29-03-2018 CDC59_RS09055 206625325a3842537fbcdb92749acc04 338 Gene3D G3DSA:1.10.287.470 91 137 0.0019 T 29-03-2018 CDC59_RS19060 e4085a9a0210395448d3daa97161e732 216 TIGRFAM TIGR02476 BluB: 5,6-dimethylbenzimidazole synthase 7 207 5.2E-79 T 29-03-2018 IPR012825 5,6-dimethylbenzimidazole synthase BluB KEGG: 00740+1.13.11.79|MetaCyc: PWY-5508|MetaCyc: PWY-5523 CDC59_RS19060 e4085a9a0210395448d3daa97161e732 216 SUPERFAMILY SSF55469 15 214 2.36E-52 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CDC59_RS19060 e4085a9a0210395448d3daa97161e732 216 Pfam PF00881 Nitroreductase family 19 183 8.3E-30 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CDC59_RS19060 e4085a9a0210395448d3daa97161e732 216 Gene3D G3DSA:3.40.109.10 2 209 6.2E-43 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CDC59_RS06390 f2fff0c1789816931fdfef8b623c71b5 240 Pfam PF06149 Protein of unknown function (DUF969) 7 223 4.1E-85 T 29-03-2018 IPR010374 Protein of unknown function DUF969 CDC59_RS22840 65a44eed4696d6b94eff39aa70380c75 328 Pfam PF05598 Transposase domain (DUF772) 51 126 3.1E-23 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS22840 65a44eed4696d6b94eff39aa70380c75 328 Pfam PF01609 Transposase DDE domain 138 312 2.4E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS20415 be00cf37efbed274aadc1516e50c9c43 179 Gene3D G3DSA:3.40.50.300 2 171 3.1E-29 T 29-03-2018 CDC59_RS20415 be00cf37efbed274aadc1516e50c9c43 179 TIGRFAM TIGR01313 therm_gnt_kin: carbohydrate kinase, thermoresistant glucokinase family 7 162 2.7E-47 T 29-03-2018 IPR006001 Carbohydrate kinase, thermoresistant glucokinase GO:0005975|GO:0016301 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 CDC59_RS20415 be00cf37efbed274aadc1516e50c9c43 179 Pfam PF01202 Shikimate kinase 13 118 5.0E-10 T 29-03-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CDC59_RS20415 be00cf37efbed274aadc1516e50c9c43 179 SUPERFAMILY SSF52540 6 164 5.33E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS20855 468a52f4cf0a52be3dbc3f317018d032 377 Gene3D G3DSA:3.10.560.10 169 257 5.7E-18 T 29-03-2018 CDC59_RS20855 468a52f4cf0a52be3dbc3f317018d032 377 Gene3D G3DSA:3.10.560.10 258 349 5.9E-19 T 29-03-2018 CDC59_RS20855 468a52f4cf0a52be3dbc3f317018d032 377 Gene3D G3DSA:3.30.1950.10 85 168 8.4E-24 T 29-03-2018 CDC59_RS20855 468a52f4cf0a52be3dbc3f317018d032 377 Pfam PF02563 Polysaccharide biosynthesis/export protein 77 173 4.4E-27 T 29-03-2018 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 CDC59_RS20855 468a52f4cf0a52be3dbc3f317018d032 377 Gene3D G3DSA:1.20.5.70 351 369 1.6E-4 T 29-03-2018 CDC59_RS20855 468a52f4cf0a52be3dbc3f317018d032 377 Pfam PF10531 SLBB domain 181 229 1.4E-6 T 29-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS20855 468a52f4cf0a52be3dbc3f317018d032 377 Pfam PF10531 SLBB domain 265 317 9.3E-6 T 29-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS19485 2e044d60d1b6fab4c3e164d8b753982e 303 Pfam PF00892 EamA-like transporter family 153 282 4.7E-12 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CDC59_RS19485 2e044d60d1b6fab4c3e164d8b753982e 303 SUPERFAMILY SSF103481 69 145 1.57E-5 T 29-03-2018 CDC59_RS19485 2e044d60d1b6fab4c3e164d8b753982e 303 SUPERFAMILY SSF103481 190 285 3.53E-12 T 29-03-2018 CDC59_RS21765 2d7c0b7adad2682655d551c168ba8b4a 83 Gene3D G3DSA:3.30.1660.10 4 68 1.3E-30 T 29-03-2018 IPR025543 Dodecin-like CDC59_RS21765 2d7c0b7adad2682655d551c168ba8b4a 83 SUPERFAMILY SSF89807 5 69 6.93E-26 T 29-03-2018 IPR009923 Dodecin CDC59_RS21765 2d7c0b7adad2682655d551c168ba8b4a 83 Pfam PF07311 Dodecin 5 68 1.5E-29 T 29-03-2018 IPR009923 Dodecin CDC59_RS02605 fa747e65d2d9ace97c6feec9b4e502ce 257 Pfam PF00977 Histidine biosynthesis protein 6 239 2.7E-90 T 29-03-2018 IPR006062 Histidine biosynthesis GO:0000105 CDC59_RS02605 fa747e65d2d9ace97c6feec9b4e502ce 257 Gene3D G3DSA:3.20.20.70 5 252 6.2E-68 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS02605 fa747e65d2d9ace97c6feec9b4e502ce 257 SUPERFAMILY SSF51366 2 256 4.87E-87 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CDC59_RS02605 fa747e65d2d9ace97c6feec9b4e502ce 257 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 2 256 4.6E-115 T 29-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 CDC59_RS02605 fa747e65d2d9ace97c6feec9b4e502ce 257 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 2 256 49.536 T 29-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 CDC59_RS06620 1cbc85043b9e4c8c6568390049fbfe33 190 Gene3D G3DSA:1.20.1250.20 4 131 0.0034 T 29-03-2018 CDC59_RS06620 1cbc85043b9e4c8c6568390049fbfe33 190 Pfam PF01169 Uncharacterized protein family UPF0016 107 181 1.4E-22 T 29-03-2018 IPR001727 Gdt1 family CDC59_RS06620 1cbc85043b9e4c8c6568390049fbfe33 190 Pfam PF01169 Uncharacterized protein family UPF0016 7 80 1.2E-18 T 29-03-2018 IPR001727 Gdt1 family CDC59_RS02470 6782c3c0d65af4171b11b09944780972 181 Pfam PF04351 Pilus assembly protein, PilP 36 175 2.3E-39 T 29-03-2018 IPR007446 Pilus assembly protein PilP CDC59_RS02470 6782c3c0d65af4171b11b09944780972 181 PIRSF PIRSF016481 12 180 1.6E-38 T 29-03-2018 IPR007446 Pilus assembly protein PilP CDC59_RS08835 ca6ff0302d99764e6aff796eda2a1a13 268 Gene3D G3DSA:1.10.3720.10 19 262 3.7E-27 T 29-03-2018 CDC59_RS08835 ca6ff0302d99764e6aff796eda2a1a13 268 SUPERFAMILY SSF161098 64 247 2.51E-34 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS08835 ca6ff0302d99764e6aff796eda2a1a13 268 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 256 6.2E-25 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS14650 8352e73b04bb2d20319e45ec2ce2a6c2 97 Hamap MF_00659 UPF0250 protein YbeD [ybeD]. 9 97 23.883 T 29-03-2018 IPR007454 Uncharacterised protein family UPF0250 CDC59_RS14650 8352e73b04bb2d20319e45ec2ce2a6c2 97 Gene3D G3DSA:3.30.70.260 13 97 6.1E-31 T 29-03-2018 CDC59_RS14650 8352e73b04bb2d20319e45ec2ce2a6c2 97 Pfam PF04359 Protein of unknown function (DUF493) 14 97 2.6E-31 T 29-03-2018 IPR007454 Uncharacterised protein family UPF0250 CDC59_RS14650 8352e73b04bb2d20319e45ec2ce2a6c2 97 SUPERFAMILY SSF117991 13 97 6.8E-28 T 29-03-2018 IPR027471 YbeD-like domain CDC59_RS22575 42088e00d5c66bf4f70928455447d6da 208 Pfam PF02525 Flavodoxin-like fold 1 199 1.4E-48 T 29-03-2018 IPR003680 Flavodoxin-like fold CDC59_RS22575 42088e00d5c66bf4f70928455447d6da 208 Gene3D G3DSA:3.40.50.360 1 208 9.1E-45 T 29-03-2018 IPR029039 Flavoprotein-like domain CDC59_RS22575 42088e00d5c66bf4f70928455447d6da 208 SUPERFAMILY SSF52218 1 204 1.92E-55 T 29-03-2018 IPR029039 Flavoprotein-like domain CDC59_RS22575 42088e00d5c66bf4f70928455447d6da 208 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 1 202 31.931 T 29-03-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 CDC59_RS21815 21d1efb13596be17b928f3480d63ee6c 390 Gene3D G3DSA:2.40.50.100 41 76 6.8E-5 T 29-03-2018 CDC59_RS21815 21d1efb13596be17b928f3480d63ee6c 390 Pfam PF13533 Biotin-lipoyl like 63 90 1.9E-6 T 29-03-2018 CDC59_RS21815 21d1efb13596be17b928f3480d63ee6c 390 Pfam PF13437 HlyD family secretion protein 239 358 1.1E-18 T 29-03-2018 CDC59_RS21815 21d1efb13596be17b928f3480d63ee6c 390 Gene3D G3DSA:1.20.1600.10 77 336 3.4E-14 T 29-03-2018 CDC59_RS21815 21d1efb13596be17b928f3480d63ee6c 390 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 67 87 6.5E-43 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CDC59_RS21815 21d1efb13596be17b928f3480d63ee6c 390 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 355 370 6.5E-43 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CDC59_RS21815 21d1efb13596be17b928f3480d63ee6c 390 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 309 332 6.5E-43 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CDC59_RS21815 21d1efb13596be17b928f3480d63ee6c 390 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 285 309 6.5E-43 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CDC59_RS21815 21d1efb13596be17b928f3480d63ee6c 390 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 25 48 6.5E-43 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CDC59_RS21815 21d1efb13596be17b928f3480d63ee6c 390 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 252 273 6.5E-43 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CDC59_RS21815 21d1efb13596be17b928f3480d63ee6c 390 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 370 390 6.5E-43 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CDC59_RS21815 21d1efb13596be17b928f3480d63ee6c 390 ProSitePatterns PS00543 HlyD family secretion proteins signature. 355 377 - T 29-03-2018 IPR006144 Secretion protein HlyD, conserved site GO:0008565|GO:0009306|GO:0016020 CDC59_RS08815 0d954faf243ea1f1abb43000534aeae6 218 SUPERFAMILY SSF52218 1 167 8.93E-32 T 29-03-2018 IPR029039 Flavoprotein-like domain CDC59_RS08815 0d954faf243ea1f1abb43000534aeae6 218 Gene3D G3DSA:3.40.50.360 1 194 4.8E-35 T 29-03-2018 IPR029039 Flavoprotein-like domain CDC59_RS08815 0d954faf243ea1f1abb43000534aeae6 218 Pfam PF03358 NADPH-dependent FMN reductase 1 143 1.1E-32 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CDC59_RS08815 0d954faf243ea1f1abb43000534aeae6 218 TIGRFAM TIGR03567 FMN_reduc_SsuE: FMN reductase 3 171 4.5E-69 T 29-03-2018 IPR020048 NADPH-dependent FMN reductase, SsuE GO:0008752|GO:0046306|GO:0055114 KEGG: 00740+1.5.1.38|MetaCyc: PWY-7723 CDC59_RS08960 77c0e85078c17127613dc711e272040f 243 Gene3D G3DSA:3.30.420.40 2 138 4.3E-35 T 29-03-2018 CDC59_RS08960 77c0e85078c17127613dc711e272040f 243 SUPERFAMILY SSF53067 111 217 2.07E-18 T 29-03-2018 CDC59_RS08960 77c0e85078c17127613dc711e272040f 243 Pfam PF00814 Glycoprotease family 36 132 8.4E-24 T 29-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CDC59_RS08960 77c0e85078c17127613dc711e272040f 243 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 4 219 1.5E-54 T 29-03-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 CDC59_RS08960 77c0e85078c17127613dc711e272040f 243 SUPERFAMILY SSF53067 3 103 5.18E-25 T 29-03-2018 CDC59_RS11515 c332561d57c462cad9485dafd6299de1 483 Pfam PF03972 MmgE/PrpD family 18 466 3.4E-162 T 29-03-2018 IPR005656 MmgE/PrpD GO:0016829 CDC59_RS11515 c332561d57c462cad9485dafd6299de1 483 SUPERFAMILY SSF103378 12 482 1.22E-162 T 29-03-2018 IPR005656 MmgE/PrpD GO:0016829 CDC59_RS11515 c332561d57c462cad9485dafd6299de1 483 Gene3D G3DSA:1.10.4100.10 2 331 3.7E-103 T 29-03-2018 CDC59_RS11515 c332561d57c462cad9485dafd6299de1 483 TIGRFAM TIGR02330 prpD: 2-methylcitrate dehydratase 13 483 3.4E-260 T 29-03-2018 IPR012705 2-methylcitrate dehydratase PrpD GO:0019629|GO:0047547|GO:0051537 KEGG: 00640+4.2.1.79 CDC59_RS11515 c332561d57c462cad9485dafd6299de1 483 Gene3D G3DSA:1.10.4100.10 388 483 6.2E-12 T 29-03-2018 CDC59_RS22800 f3c14faccfc51840860dfb1a0c9f3c1e 586 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 263 317 - T 29-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS22800 f3c14faccfc51840860dfb1a0c9f3c1e 586 SUPERFAMILY SSF81442 15 537 3.66E-154 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS22800 f3c14faccfc51840860dfb1a0c9f3c1e 586 PRINTS PR01165 Cytochrome c oxidase subunit I signature 366 384 3.5E-75 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS22800 f3c14faccfc51840860dfb1a0c9f3c1e 586 PRINTS PR01165 Cytochrome c oxidase subunit I signature 444 465 3.5E-75 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS22800 f3c14faccfc51840860dfb1a0c9f3c1e 586 PRINTS PR01165 Cytochrome c oxidase subunit I signature 18 43 3.5E-75 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS22800 f3c14faccfc51840860dfb1a0c9f3c1e 586 PRINTS PR01165 Cytochrome c oxidase subunit I signature 394 413 3.5E-75 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS22800 f3c14faccfc51840860dfb1a0c9f3c1e 586 PRINTS PR01165 Cytochrome c oxidase subunit I signature 331 352 3.5E-75 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS22800 f3c14faccfc51840860dfb1a0c9f3c1e 586 PRINTS PR01165 Cytochrome c oxidase subunit I signature 261 282 3.5E-75 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS22800 f3c14faccfc51840860dfb1a0c9f3c1e 586 PRINTS PR01165 Cytochrome c oxidase subunit I signature 307 322 3.5E-75 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS22800 f3c14faccfc51840860dfb1a0c9f3c1e 586 PRINTS PR01165 Cytochrome c oxidase subunit I signature 66 89 3.5E-75 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS22800 f3c14faccfc51840860dfb1a0c9f3c1e 586 PRINTS PR01165 Cytochrome c oxidase subunit I signature 94 118 3.5E-75 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS22800 f3c14faccfc51840860dfb1a0c9f3c1e 586 Gene3D G3DSA:1.20.210.10 14 548 2.6E-177 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS22800 f3c14faccfc51840860dfb1a0c9f3c1e 586 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 28 491 3.1E-134 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS22800 f3c14faccfc51840860dfb1a0c9f3c1e 586 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 19 541 8.8E-207 T 29-03-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 CDC59_RS17925 5c161cd892f37d85bbdbe2807c37c6a5 184 Gene3D G3DSA:3.40.630.30 6 176 1.0E-32 T 29-03-2018 CDC59_RS17925 5c161cd892f37d85bbdbe2807c37c6a5 184 Pfam PF13673 Acetyltransferase (GNAT) domain 39 153 5.7E-15 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CDC59_RS17925 5c161cd892f37d85bbdbe2807c37c6a5 184 SUPERFAMILY SSF55729 8 173 1.01E-32 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDC59_RS04750 2ca15f63e2eb1fecd87c90a1ab7f1149 172 Gene3D G3DSA:3.30.1330.60 35 172 3.0E-34 T 29-03-2018 IPR006665 OmpA-like domain CDC59_RS04750 2ca15f63e2eb1fecd87c90a1ab7f1149 172 SUPERFAMILY SSF103088 54 171 2.75E-34 T 29-03-2018 IPR006665 OmpA-like domain CDC59_RS04750 2ca15f63e2eb1fecd87c90a1ab7f1149 172 PRINTS PR01021 OMPA domain signature 117 133 1.7E-16 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CDC59_RS04750 2ca15f63e2eb1fecd87c90a1ab7f1149 172 PRINTS PR01021 OMPA domain signature 102 117 1.7E-16 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CDC59_RS04750 2ca15f63e2eb1fecd87c90a1ab7f1149 172 PRINTS PR01021 OMPA domain signature 72 94 1.7E-16 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CDC59_RS04750 2ca15f63e2eb1fecd87c90a1ab7f1149 172 TIGRFAM TIGR02802 Pal_lipo: peptidoglycan-associated lipoprotein 69 172 1.7E-44 T 29-03-2018 IPR014169 Peptidoglycan-associated lipoprotein GO:0009279 CDC59_RS04750 2ca15f63e2eb1fecd87c90a1ab7f1149 172 ProSitePatterns PS01068 OmpA-like domain. 104 148 - T 29-03-2018 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 CDC59_RS04750 2ca15f63e2eb1fecd87c90a1ab7f1149 172 Pfam PF00691 OmpA family 71 166 5.3E-22 T 29-03-2018 IPR006665 OmpA-like domain CDC59_RS15885 15677f3dcc9ee91e83921a62948a857d 418 Pfam PF10282 Lactonase, 7-bladed beta-propeller 55 416 8.0E-104 T 29-03-2018 IPR019405 Lactonase, 7-bladed beta propeller CDC59_RS15885 15677f3dcc9ee91e83921a62948a857d 418 Gene3D G3DSA:2.130.10.10 321 417 2.0E-8 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CDC59_RS15885 15677f3dcc9ee91e83921a62948a857d 418 Gene3D G3DSA:2.130.10.10 52 191 3.2E-12 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CDC59_RS15885 15677f3dcc9ee91e83921a62948a857d 418 SUPERFAMILY SSF51004 82 416 1.44E-41 T 29-03-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain CDC59_RS15885 15677f3dcc9ee91e83921a62948a857d 418 Gene3D G3DSA:2.120.10.30 192 320 2.8E-18 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CDC59_RS14240 e4999a101756900763296184317b2825 117 Gene3D G3DSA:3.30.160.100 1 104 5.9E-31 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CDC59_RS14240 e4999a101756900763296184317b2825 117 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 4 97 3.9E-25 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CDC59_RS14240 e4999a101756900763296184317b2825 117 SUPERFAMILY SSF69754 1 106 1.44E-32 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CDC59_RS14240 e4999a101756900763296184317b2825 117 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 103 5.9E-28 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CDC59_RS14860 b8a2650277f404c9eece097b7fe89367 146 Pfam PF00072 Response regulator receiver domain 15 127 3.8E-19 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS14860 b8a2650277f404c9eece097b7fe89367 146 Gene3D G3DSA:3.40.50.2300 3 138 7.3E-25 T 29-03-2018 CDC59_RS14860 b8a2650277f404c9eece097b7fe89367 146 SUPERFAMILY SSF52172 11 139 1.02E-23 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS14860 b8a2650277f404c9eece097b7fe89367 146 SMART SM00448 13 127 7.4E-19 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS07455 e39bbdeb5acb52072217e77c8523e4ec 82 Pfam PF04226 Transglycosylase associated protein 33 80 4.2E-14 T 29-03-2018 IPR007341 Transglycosylase-associated protein GO:0016021 CDC59_RS16305 b482a07f79a661bbac1f89d8310b6784 257 Gene3D G3DSA:3.40.190.10 26 122 8.2E-14 T 29-03-2018 CDC59_RS16305 b482a07f79a661bbac1f89d8310b6784 257 Gene3D G3DSA:3.40.190.10 123 216 3.2E-32 T 29-03-2018 CDC59_RS16305 b482a07f79a661bbac1f89d8310b6784 257 PIRSF PIRSF004846 1 257 6.3E-73 T 29-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 CDC59_RS16305 b482a07f79a661bbac1f89d8310b6784 257 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 37 253 2.6E-59 T 29-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 CDC59_RS16305 b482a07f79a661bbac1f89d8310b6784 257 SUPERFAMILY SSF53850 31 257 3.23E-65 T 29-03-2018 CDC59_RS16305 b482a07f79a661bbac1f89d8310b6784 257 Pfam PF13531 Bacterial extracellular solute-binding protein 32 254 2.1E-50 T 29-03-2018 CDC59_RS01165 cf06c76fde36336b5608bfd0bedcb5f8 116 SUPERFAMILY SSF46626 19 111 3.64E-13 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS01165 cf06c76fde36336b5608bfd0bedcb5f8 116 Gene3D G3DSA:1.10.760.10 3 111 4.7E-13 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS08355 abc8f101794e882f9e3d8dbbc5b34d91 278 Pfam PF01261 Xylose isomerase-like TIM barrel 22 207 1.5E-36 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CDC59_RS08355 abc8f101794e882f9e3d8dbbc5b34d91 278 SUPERFAMILY SSF51658 2 246 6.81E-62 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CDC59_RS08355 abc8f101794e882f9e3d8dbbc5b34d91 278 Gene3D G3DSA:3.20.20.150 1 261 7.1E-58 T 29-03-2018 CDC59_RS11940 3ddbed5e98c220a36d53285f4f5c0872 200 Pfam PF01810 LysE type translocator 17 196 1.8E-13 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CDC59_RS05730 d85b617bc8918ce705583c06ef189520 316 Gene3D G3DSA:1.20.1600.10 1 262 1.3E-29 T 29-03-2018 CDC59_RS05730 d85b617bc8918ce705583c06ef189520 316 Gene3D G3DSA:1.20.1600.10 263 315 3.8E-5 T 29-03-2018 CDC59_RS05730 d85b617bc8918ce705583c06ef189520 316 SUPERFAMILY SSF56954 2 304 6.28E-43 T 29-03-2018 CDC59_RS05730 d85b617bc8918ce705583c06ef189520 316 Pfam PF02321 Outer membrane efflux protein 137 262 1.1E-10 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CDC59_RS18530 ac796acb985d3dfae26c8a9fa9159f79 174 Pfam PF07007 Lysozyme inhibitor LprI 32 136 5.4E-15 T 29-03-2018 IPR009739 Lysozyme inhibitor LprI, N-terminal CDC59_RS11460 0e45b1e4b89fb0fcabb60cb6826fe2c7 95 Gene3D G3DSA:1.10.150.250 12 95 3.8E-21 T 29-03-2018 CDC59_RS11460 0e45b1e4b89fb0fcabb60cb6826fe2c7 95 SUPERFAMILY SSF109910 11 90 3.92E-20 T 29-03-2018 IPR005631 Flavinator of succinate dehydrogenase CDC59_RS11460 0e45b1e4b89fb0fcabb60cb6826fe2c7 95 Pfam PF03937 Flavinator of succinate dehydrogenase 18 78 1.2E-20 T 29-03-2018 IPR005631 Flavinator of succinate dehydrogenase CDC59_RS08445 c98b39689a9bbbb0f36d9be9fd89ee21 293 SUPERFAMILY SSF161098 55 282 1.31E-52 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS08445 c98b39689a9bbbb0f36d9be9fd89ee21 293 Gene3D G3DSA:1.10.3720.10 12 293 1.2E-43 T 29-03-2018 CDC59_RS08445 c98b39689a9bbbb0f36d9be9fd89ee21 293 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 292 9.5E-18 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS11910 afdca9d6b9b805a52ab2a90fbaeff56c 339 Gene3D G3DSA:3.40.50.1820 123 339 8.9E-35 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS11910 afdca9d6b9b805a52ab2a90fbaeff56c 339 Pfam PF12697 Alpha/beta hydrolase family 143 298 2.6E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS11910 afdca9d6b9b805a52ab2a90fbaeff56c 339 SUPERFAMILY SSF53474 140 324 7.3E-34 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS12770 82554ebed470984de1f6a3dfe7812374 125 Pfam PF07681 DoxX 13 79 2.2E-10 T 29-03-2018 IPR032808 DoxX family CDC59_RS14260 d95277dfc25ac0665cd54a9caa67f7b0 297 Gene3D G3DSA:3.40.50.300 1 169 1.4E-8 T 29-03-2018 CDC59_RS14260 d95277dfc25ac0665cd54a9caa67f7b0 297 PIRSF PIRSF005052 1 297 9.5E-114 T 29-03-2018 IPR005337 RapZ-like family GO:0005524 CDC59_RS14260 d95277dfc25ac0665cd54a9caa67f7b0 297 SUPERFAMILY SSF52540 1 168 2.66E-9 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS14260 d95277dfc25ac0665cd54a9caa67f7b0 297 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 1 294 39.548 T 29-03-2018 IPR005337 RapZ-like family GO:0005524 CDC59_RS14260 d95277dfc25ac0665cd54a9caa67f7b0 297 Pfam PF03668 P-loop ATPase protein family 1 292 5.8E-93 T 29-03-2018 IPR005337 RapZ-like family GO:0005524 CDC59_RS22570 079a057b62b15b068497ead8ea095f5d 315 Pfam PF03466 LysR substrate binding domain 89 293 9.3E-35 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS22570 079a057b62b15b068497ead8ea095f5d 315 Gene3D G3DSA:3.40.190.10 177 265 1.2E-14 T 29-03-2018 CDC59_RS22570 079a057b62b15b068497ead8ea095f5d 315 Gene3D G3DSA:3.40.190.10 79 176 3.1E-14 T 29-03-2018 CDC59_RS22570 079a057b62b15b068497ead8ea095f5d 315 SUPERFAMILY SSF46785 3 112 2.72E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS22570 079a057b62b15b068497ead8ea095f5d 315 SUPERFAMILY SSF53850 89 296 2.35E-37 T 29-03-2018 CDC59_RS22570 079a057b62b15b068497ead8ea095f5d 315 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 3.3E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS22570 079a057b62b15b068497ead8ea095f5d 315 Gene3D G3DSA:1.10.10.10 2 78 1.2E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS13430 b23c1cf0ec64dd555839ff14fafddc66 293 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 3 293 1.3E-126 T 29-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CDC59_RS13430 b23c1cf0ec64dd555839ff14fafddc66 293 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 157 186 - T 29-03-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site CDC59_RS13430 b23c1cf0ec64dd555839ff14fafddc66 293 Gene3D G3DSA:3.40.50.261 125 293 7.5E-50 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CDC59_RS13430 b23c1cf0ec64dd555839ff14fafddc66 293 SUPERFAMILY SSF51735 1 127 1.34E-35 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS13430 b23c1cf0ec64dd555839ff14fafddc66 293 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 241 254 - T 29-03-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site CDC59_RS13430 b23c1cf0ec64dd555839ff14fafddc66 293 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 293 40.232 T 29-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CDC59_RS13430 b23c1cf0ec64dd555839ff14fafddc66 293 SMART SM00881 4 103 1.1E-28 T 29-03-2018 IPR003781 CoA-binding GO:0048037 CDC59_RS13430 b23c1cf0ec64dd555839ff14fafddc66 293 Gene3D G3DSA:3.40.50.720 1 124 5.0E-39 T 29-03-2018 CDC59_RS13430 b23c1cf0ec64dd555839ff14fafddc66 293 PRINTS PR01798 Succinyl-CoA synthase signature 85 102 1.0E-33 T 29-03-2018 CDC59_RS13430 b23c1cf0ec64dd555839ff14fafddc66 293 PRINTS PR01798 Succinyl-CoA synthase signature 213 226 1.0E-33 T 29-03-2018 CDC59_RS13430 b23c1cf0ec64dd555839ff14fafddc66 293 PRINTS PR01798 Succinyl-CoA synthase signature 245 262 1.0E-33 T 29-03-2018 CDC59_RS13430 b23c1cf0ec64dd555839ff14fafddc66 293 PRINTS PR01798 Succinyl-CoA synthase signature 182 200 1.0E-33 T 29-03-2018 CDC59_RS13430 b23c1cf0ec64dd555839ff14fafddc66 293 PIRSF PIRSF001553 1 293 1.7E-117 T 29-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CDC59_RS13430 b23c1cf0ec64dd555839ff14fafddc66 293 Pfam PF00549 CoA-ligase 156 268 3.1E-15 T 29-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CDC59_RS13430 b23c1cf0ec64dd555839ff14fafddc66 293 SUPERFAMILY SSF52210 128 292 1.28E-52 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CDC59_RS13430 b23c1cf0ec64dd555839ff14fafddc66 293 Pfam PF02629 CoA binding domain 6 102 5.2E-24 T 29-03-2018 IPR003781 CoA-binding GO:0048037 CDC59_RS11275 8048a491befd6fe26f513bc20699818e 660 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 27 658 2.9E-297 T 29-03-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 CDC59_RS11275 8048a491befd6fe26f513bc20699818e 660 ProSitePatterns PS00455 Putative AMP-binding domain signature. 267 278 - T 29-03-2018 IPR020845 AMP-binding, conserved site CDC59_RS11275 8048a491befd6fe26f513bc20699818e 660 Gene3D G3DSA:3.40.50.980 80 272 8.7E-48 T 29-03-2018 CDC59_RS11275 8048a491befd6fe26f513bc20699818e 660 Pfam PF00501 AMP-binding enzyme 95 535 5.9E-97 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CDC59_RS11275 8048a491befd6fe26f513bc20699818e 660 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 32 87 8.3E-21 T 29-03-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 CDC59_RS11275 8048a491befd6fe26f513bc20699818e 660 Gene3D G3DSA:3.30.300.30 529 644 2.4E-26 T 29-03-2018 CDC59_RS11275 8048a491befd6fe26f513bc20699818e 660 SUPERFAMILY SSF56801 15 656 2.09E-174 T 29-03-2018 CDC59_RS11275 8048a491befd6fe26f513bc20699818e 660 Gene3D G3DSA:2.30.38.10 440 528 8.3E-11 T 29-03-2018 CDC59_RS11275 8048a491befd6fe26f513bc20699818e 660 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 9 660 51.509 T 29-03-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 CDC59_RS11275 8048a491befd6fe26f513bc20699818e 660 Pfam PF13193 AMP-binding enzyme C-terminal domain 544 625 2.6E-26 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CDC59_RS11275 8048a491befd6fe26f513bc20699818e 660 Gene3D G3DSA:3.40.50.980 273 439 2.6E-38 T 29-03-2018 CDC59_RS02455 5b88402153c1dbe19d2db548475852b9 356 Pfam PF11104 Type IV pilus assembly protein PilM; 11 354 9.2E-117 T 29-03-2018 IPR005883 Type IV pilus assembly protein PilM CDC59_RS02455 5b88402153c1dbe19d2db548475852b9 356 SUPERFAMILY SSF53067 196 354 9.5E-16 T 29-03-2018 CDC59_RS02455 5b88402153c1dbe19d2db548475852b9 356 Gene3D G3DSA:3.30.420.40 181 319 0.0014 T 29-03-2018 CDC59_RS02455 5b88402153c1dbe19d2db548475852b9 356 SUPERFAMILY SSF53067 9 174 1.91E-12 T 29-03-2018 CDC59_RS02455 5b88402153c1dbe19d2db548475852b9 356 Gene3D G3DSA:3.30.420.40 5 169 2.8E-30 T 29-03-2018 CDC59_RS02455 5b88402153c1dbe19d2db548475852b9 356 PIRSF PIRSF019169 2 356 7.6E-92 T 29-03-2018 IPR005883 Type IV pilus assembly protein PilM CDC59_RS02455 5b88402153c1dbe19d2db548475852b9 356 TIGRFAM TIGR01175 pilM: type IV pilus assembly protein PilM 8 355 1.1E-67 T 29-03-2018 IPR005883 Type IV pilus assembly protein PilM CDC59_RS02455 5b88402153c1dbe19d2db548475852b9 356 SMART SM00842 9 176 1.9E-4 T 29-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 CDC59_RS18260 4ea063658a4865d70fc9725ee9c35757 132 Pfam PF04343 Protein of unknown function, DUF488 12 122 1.4E-13 T 29-03-2018 IPR007438 Protein of unknown function DUF488 CDC59_RS02545 c16970c824f3e1b848536cc0066fab33 104 SUPERFAMILY SSF52091 2 93 6.47E-13 T 29-03-2018 IPR002645 STAS domain CDC59_RS02545 c16970c824f3e1b848536cc0066fab33 104 Gene3D G3DSA:3.30.750.24 1 101 1.5E-13 T 29-03-2018 IPR002645 STAS domain CDC59_RS02545 c16970c824f3e1b848536cc0066fab33 104 Pfam PF13466 STAS domain 2 86 1.1E-20 T 29-03-2018 IPR002645 STAS domain CDC59_RS20010 fcc0405ba125fe91075af4ba0adfd37a 528 Gene3D G3DSA:3.40.309.10 277 455 2.2E-20 T 29-03-2018 CDC59_RS20010 fcc0405ba125fe91075af4ba0adfd37a 528 Pfam PF00171 Aldehyde dehydrogenase family 19 458 1.2E-42 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CDC59_RS20010 fcc0405ba125fe91075af4ba0adfd37a 528 Gene3D G3DSA:3.40.605.10 4 276 3.0E-49 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CDC59_RS20010 fcc0405ba125fe91075af4ba0adfd37a 528 SUPERFAMILY SSF53720 19 519 2.09E-101 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CDC59_RS23460 c9efc24b4dc6d2fa77f8707ae415d595 290 Gene3D G3DSA:3.40.50.300 6 287 1.0E-4 T 29-03-2018 CDC59_RS23460 c9efc24b4dc6d2fa77f8707ae415d595 290 SUPERFAMILY SSF52540 13 65 6.29E-5 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS23460 c9efc24b4dc6d2fa77f8707ae415d595 290 Pfam PF13479 AAA domain 18 253 1.0E-44 T 29-03-2018 CDC59_RS20180 3ff1a5b846f93630b4152bbd9324be45 217 ProSitePatterns PS01061 Flagella transport protein fliP family signature 2. 193 205 - T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CDC59_RS20180 3ff1a5b846f93630b4152bbd9324be45 217 ProSitePatterns PS01060 Flagella transport protein fliP family signature 1. 145 160 - T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CDC59_RS20180 3ff1a5b846f93630b4152bbd9324be45 217 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 49 68 7.5E-63 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CDC59_RS20180 3ff1a5b846f93630b4152bbd9324be45 217 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 190 215 7.5E-63 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CDC59_RS20180 3ff1a5b846f93630b4152bbd9324be45 217 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 166 187 7.5E-63 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CDC59_RS20180 3ff1a5b846f93630b4152bbd9324be45 217 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 145 165 7.5E-63 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CDC59_RS20180 3ff1a5b846f93630b4152bbd9324be45 217 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 10 29 7.5E-63 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CDC59_RS20180 3ff1a5b846f93630b4152bbd9324be45 217 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 29 49 7.5E-63 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CDC59_RS20180 3ff1a5b846f93630b4152bbd9324be45 217 TIGRFAM TIGR01102 yscR: type III secretion apparatus protein, YscR/HrcR family 9 212 5.6E-88 T 29-03-2018 IPR005773 Yop virulence translocation protein R GO:0015031|GO:0016021 CDC59_RS20180 3ff1a5b846f93630b4152bbd9324be45 217 Pfam PF00813 FliP family 14 212 1.5E-61 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CDC59_RS22590 264b65e31d798597f6de0bf216fed25f 113 Pfam PF07369 Protein of unknown function (DUF1488) 16 73 3.9E-10 T 29-03-2018 IPR009962 Protein of unknown function DUF1488 CDC59_RS22590 264b65e31d798597f6de0bf216fed25f 113 SUPERFAMILY SSF160272 15 71 2.62E-6 T 29-03-2018 IPR009962 Protein of unknown function DUF1488 CDC59_RS22590 264b65e31d798597f6de0bf216fed25f 113 Gene3D G3DSA:3.30.160.140 12 74 9.2E-7 T 29-03-2018 IPR009962 Protein of unknown function DUF1488 CDC59_RS02870 6db2fdfbdc848de44f92ee042ee3bd7b 248 Gene3D G3DSA:3.10.450.70 30 93 1.4E-18 T 29-03-2018 CDC59_RS02870 6db2fdfbdc848de44f92ee042ee3bd7b 248 Pfam PF13098 Thioredoxin-like domain 120 240 3.2E-30 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS02870 6db2fdfbdc848de44f92ee042ee3bd7b 248 SUPERFAMILY SSF52833 93 240 5.78E-34 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS02870 6db2fdfbdc848de44f92ee042ee3bd7b 248 Gene3D G3DSA:3.40.30.10 111 248 5.4E-19 T 29-03-2018 CDC59_RS02870 6db2fdfbdc848de44f92ee042ee3bd7b 248 SUPERFAMILY SSF54423 46 94 1.24E-12 T 29-03-2018 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal CDC59_RS02870 6db2fdfbdc848de44f92ee042ee3bd7b 248 Pfam PF10411 Disulfide bond isomerase protein N-terminus 42 91 3.2E-18 T 29-03-2018 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal CDC59_RS00615 775eb281d2d6a486ae8a222f377165b2 325 Gene3D G3DSA:3.40.50.720 1 195 5.2E-38 T 29-03-2018 CDC59_RS00615 775eb281d2d6a486ae8a222f377165b2 325 Pfam PF02558 Ketopantoate reductase PanE/ApbA 4 168 6.5E-27 T 29-03-2018 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CDC59_RS00615 775eb281d2d6a486ae8a222f377165b2 325 SUPERFAMILY SSF48179 197 318 1.63E-26 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CDC59_RS00615 775eb281d2d6a486ae8a222f377165b2 325 SUPERFAMILY SSF51735 3 184 1.35E-17 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS00615 775eb281d2d6a486ae8a222f377165b2 325 Gene3D G3DSA:1.10.1040.10 196 323 1.2E-28 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CDC59_RS00615 775eb281d2d6a486ae8a222f377165b2 325 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 197 317 2.7E-24 T 29-03-2018 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CDC59_RS11615 4fd0eca4510db6e8ca0bb2230e80446c 230 Gene3D G3DSA:1.20.1050.10 146 200 6.4E-17 T 29-03-2018 CDC59_RS11615 4fd0eca4510db6e8ca0bb2230e80446c 230 Gene3D G3DSA:1.20.1050.10 93 145 5.1E-17 T 29-03-2018 CDC59_RS11615 4fd0eca4510db6e8ca0bb2230e80446c 230 Pfam PF00043 Glutathione S-transferase, C-terminal domain 116 196 1.8E-11 T 29-03-2018 IPR004046 Glutathione S-transferase, C-terminal CDC59_RS11615 4fd0eca4510db6e8ca0bb2230e80446c 230 Pfam PF02798 Glutathione S-transferase, N-terminal domain 3 79 5.1E-14 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CDC59_RS11615 4fd0eca4510db6e8ca0bb2230e80446c 230 SUPERFAMILY SSF52833 2 84 1.42E-22 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS11615 4fd0eca4510db6e8ca0bb2230e80446c 230 Gene3D G3DSA:3.40.30.10 1 92 5.2E-26 T 29-03-2018 CDC59_RS11615 4fd0eca4510db6e8ca0bb2230e80446c 230 SUPERFAMILY SSF47616 77 204 1.21E-39 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like CDC59_RS13655 152eb76a39d3f9cf84f446725b4fe921 811 Gene3D G3DSA:2.60.450.10 94 250 4.5E-15 T 29-03-2018 CDC59_RS13655 152eb76a39d3f9cf84f446725b4fe921 811 Pfam PF04453 Organic solvent tolerance protein 342 717 1.3E-106 T 29-03-2018 IPR007543 Organic solvent tolerance protein, C-terminal GO:0010033|GO:0019867|GO:0061024 CDC59_RS13655 152eb76a39d3f9cf84f446725b4fe921 811 Hamap MF_01411 LPS-assembly protein LptD [lptD]. 64 778 20.397 T 29-03-2018 IPR020889 LPS-assembly protein LptD GO:0009279|GO:0010033|GO:0015920|GO:0043165 CDC59_RS15670 8b18ba014e0f457a6500f317e498126e 151 SUPERFAMILY SSF159894 14 112 1.6E-26 T 29-03-2018 CDC59_RS15670 8b18ba014e0f457a6500f317e498126e 151 Gene3D G3DSA:3.30.1460.30 9 113 2.6E-24 T 29-03-2018 CDC59_RS15670 8b18ba014e0f457a6500f317e498126e 151 Pfam PF04993 TfoX N-terminal domain 20 110 1.9E-28 T 29-03-2018 IPR007076 TfoX, N-terminal CDC59_RS11330 ff632a16e428cdac335f393fb046c7d2 137 Pfam PF02472 Biopolymer transport protein ExbD/TolR 13 134 8.3E-30 T 29-03-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 CDC59_RS06310 03ea52f539c8e78b3e2bc2404414f1e4 144 Pfam PF02142 MGS-like domain 28 120 1.5E-17 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CDC59_RS06310 03ea52f539c8e78b3e2bc2404414f1e4 144 PIRSF PIRSF006614 10 144 2.2E-58 T 29-03-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 CDC59_RS06310 03ea52f539c8e78b3e2bc2404414f1e4 144 TIGRFAM TIGR00160 MGSA: methylglyoxal synthase 13 133 4.3E-53 T 29-03-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 CDC59_RS06310 03ea52f539c8e78b3e2bc2404414f1e4 144 ProSitePatterns PS01335 Methylglyoxal synthase active site. 67 75 - T 29-03-2018 IPR018148 Methylglyoxal synthase, active site GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 CDC59_RS06310 03ea52f539c8e78b3e2bc2404414f1e4 144 Hamap MF_00549 Methylglyoxal synthase [mgsA]. 14 133 32.781 T 29-03-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 CDC59_RS06310 03ea52f539c8e78b3e2bc2404414f1e4 144 SUPERFAMILY SSF52335 7 137 4.19E-52 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CDC59_RS06310 03ea52f539c8e78b3e2bc2404414f1e4 144 Gene3D G3DSA:3.40.50.1380 4 144 3.7E-37 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CDC59_RS06310 03ea52f539c8e78b3e2bc2404414f1e4 144 SMART SM00851 27 120 3.9E-26 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CDC59_RS16925 b760b12fb116768e1ca39bf7a37009cf 152 Gene3D G3DSA:1.10.150.120 74 152 4.6E-27 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CDC59_RS16925 b760b12fb116768e1ca39bf7a37009cf 152 SUPERFAMILY SSF54292 2 77 6.69E-25 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CDC59_RS16925 b760b12fb116768e1ca39bf7a37009cf 152 Gene3D G3DSA:3.10.20.30 1 73 8.1E-27 T 29-03-2018 IPR012675 Beta-grasp domain CDC59_RS16925 b760b12fb116768e1ca39bf7a37009cf 152 Pfam PF01799 [2Fe-2S] binding domain 72 144 5.5E-24 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CDC59_RS16925 b760b12fb116768e1ca39bf7a37009cf 152 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 5 54 7.0E-9 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CDC59_RS16925 b760b12fb116768e1ca39bf7a37009cf 152 SUPERFAMILY SSF47741 83 150 4.84E-28 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CDC59_RS16925 b760b12fb116768e1ca39bf7a37009cf 152 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 38 46 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CDC59_RS15455 11fe2519f93115e21a3a65d2f7d24af2 261 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 2 253 7.8E-71 T 29-03-2018 CDC59_RS15455 11fe2519f93115e21a3a65d2f7d24af2 261 SUPERFAMILY SSF56219 2 256 3.93E-73 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CDC59_RS15455 11fe2519f93115e21a3a65d2f7d24af2 261 Gene3D G3DSA:3.60.10.10 1 260 1.4E-51 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CDC59_RS15455 11fe2519f93115e21a3a65d2f7d24af2 261 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 2 255 2.7E-76 T 29-03-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 CDC59_RS15455 11fe2519f93115e21a3a65d2f7d24af2 261 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 29 38 - T 29-03-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 CDC59_RS15455 11fe2519f93115e21a3a65d2f7d24af2 261 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 6 248 2.1E-15 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CDC59_RS21325 41a504f47c3167860799e8d9f3af3315 328 Gene3D G3DSA:3.40.50.1820 19 324 7.7E-37 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS21325 41a504f47c3167860799e8d9f3af3315 328 Pfam PF12146 Serine aminopeptidase, S33 65 305 4.7E-22 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 CDC59_RS21325 41a504f47c3167860799e8d9f3af3315 328 SUPERFAMILY SSF53474 249 320 3.46E-40 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS21325 41a504f47c3167860799e8d9f3af3315 328 SUPERFAMILY SSF53474 37 171 3.46E-40 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS21325 41a504f47c3167860799e8d9f3af3315 328 PRINTS PR00111 Alpha/beta hydrolase fold signature 137 150 5.3E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS21325 41a504f47c3167860799e8d9f3af3315 328 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 105 5.3E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS02765 77a4adfd7f3fa5c93985d86a591e46f7 122 TIGRFAM TIGR02847 CyoD: cytochrome o ubiquinol oxidase subunit IV 26 120 4.9E-38 T 29-03-2018 IPR014210 Cytochrome o ubiquinol oxidase subunit IV GO:0008827|GO:0015990|GO:0016021 CDC59_RS02765 77a4adfd7f3fa5c93985d86a591e46f7 122 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 32 105 9.7E-17 T 29-03-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 CDC59_RS12980 54547483aa05ac9e939c816f5303036a 215 Gene3D G3DSA:3.50.70.10 34 198 1.7E-22 T 29-03-2018 IPR016088 Chalcone isomerase, 3-layer sandwich GO:0009813|GO:0045430 CDC59_RS12980 54547483aa05ac9e939c816f5303036a 215 Pfam PF16036 Chalcone isomerase-like 46 214 4.1E-50 T 29-03-2018 IPR016087 Chalcone isomerase GO:0016872 CDC59_RS12980 54547483aa05ac9e939c816f5303036a 215 SUPERFAMILY SSF54626 45 214 4.58E-27 T 29-03-2018 IPR016087 Chalcone isomerase GO:0016872 CDC59_RS18750 f63eccbe0b318e81965f25796cd13db3 377 Pfam PF00924 Mechanosensitive ion channel 137 336 7.8E-48 T 29-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 CDC59_RS18750 f63eccbe0b318e81965f25796cd13db3 377 Gene3D G3DSA:2.30.30.60 195 244 3.5E-11 T 29-03-2018 CDC59_RS18750 f63eccbe0b318e81965f25796cd13db3 377 Gene3D G3DSA:3.30.70.100 248 335 2.3E-14 T 29-03-2018 CDC59_RS18750 f63eccbe0b318e81965f25796cd13db3 377 SUPERFAMILY SSF50182 180 244 1.41E-12 T 29-03-2018 IPR010920 LSM domain CDC59_RS18750 f63eccbe0b318e81965f25796cd13db3 377 SUPERFAMILY SSF82861 93 178 4.18E-13 T 29-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 CDC59_RS18750 f63eccbe0b318e81965f25796cd13db3 377 SUPERFAMILY SSF82689 246 346 2.48E-16 T 29-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 CDC59_RS01140 41cc9b9f9912b16119a409d7863eaa48 218 SUPERFAMILY SSF56281 6 207 2.17E-55 T 29-03-2018 IPR001279 Metallo-beta-lactamase CDC59_RS01140 41cc9b9f9912b16119a409d7863eaa48 218 Gene3D G3DSA:3.60.15.10 1 217 2.6E-43 T 29-03-2018 IPR001279 Metallo-beta-lactamase CDC59_RS01140 41cc9b9f9912b16119a409d7863eaa48 218 Pfam PF00753 Metallo-beta-lactamase superfamily 9 191 7.0E-33 T 29-03-2018 IPR001279 Metallo-beta-lactamase CDC59_RS01140 41cc9b9f9912b16119a409d7863eaa48 218 SMART SM00849 12 191 3.5E-35 T 29-03-2018 IPR001279 Metallo-beta-lactamase CDC59_RS23710 d4f0abd4c505e911ceedf3a163ba4385 305 SUPERFAMILY SSF51735 9 260 3.11E-29 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS23710 d4f0abd4c505e911ceedf3a163ba4385 305 Pfam PF01370 NAD dependent epimerase/dehydratase family 10 197 2.2E-20 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CDC59_RS23710 d4f0abd4c505e911ceedf3a163ba4385 305 Gene3D G3DSA:3.40.50.720 8 281 1.2E-26 T 29-03-2018 CDC59_RS01185 fbb5ea5e8dc4df2a330afe7d1b5d6058 163 TIGRFAM TIGR04488 SoxY_true_GGCGG: thiosulfate oxidation carrier protein SoxY 15 163 6.7E-50 T 29-03-2018 IPR016568 Sulphur oxidation, SoxY CDC59_RS01185 fbb5ea5e8dc4df2a330afe7d1b5d6058 163 PIRSF PIRSF010312 10 163 3.9E-56 T 29-03-2018 IPR016568 Sulphur oxidation, SoxY CDC59_RS01185 fbb5ea5e8dc4df2a330afe7d1b5d6058 163 Pfam PF13501 Sulfur oxidation protein SoxY 60 161 5.5E-30 T 29-03-2018 IPR032711 Ig-like SoxY domain CDC59_RS14890 cbe0c2df38b7d7ceb9a4b3af979e9647 218 Gene3D G3DSA:3.40.30.10 28 212 5.4E-41 T 29-03-2018 CDC59_RS14890 cbe0c2df38b7d7ceb9a4b3af979e9647 218 Pfam PF01323 DSBA-like thioredoxin domain 49 195 1.2E-12 T 29-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 CDC59_RS14890 cbe0c2df38b7d7ceb9a4b3af979e9647 218 ProSitePatterns PS00194 Thioredoxin family active site. 49 67 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CDC59_RS14890 cbe0c2df38b7d7ceb9a4b3af979e9647 218 PIRSF PIRSF001488 1 217 3.0E-47 T 29-03-2018 IPR023205 Thiol:disulphide interchange protein DsbA/DsbL CDC59_RS14890 cbe0c2df38b7d7ceb9a4b3af979e9647 218 SUPERFAMILY SSF52833 26 213 1.26E-41 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS02005 01575224b8ba468b926831ea0e99bc4c 77 SUPERFAMILY SSF89447 1 72 1.2E-13 T 29-03-2018 CDC59_RS02005 01575224b8ba468b926831ea0e99bc4c 77 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 5 39 7.8E-13 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CDC59_RS02005 01575224b8ba468b926831ea0e99bc4c 77 Gene3D G3DSA:2.10.260.10 1 40 5.3E-15 T 29-03-2018 CDC59_RS02005 01575224b8ba468b926831ea0e99bc4c 77 SMART SM00966 4 50 2.5E-11 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CDC59_RS12645 dc728ee48f8f65e0763675d21ed4d144 174 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 21 174 16.831 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CDC59_RS12645 dc728ee48f8f65e0763675d21ed4d144 174 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 114 129 1.7E-18 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CDC59_RS12645 dc728ee48f8f65e0763675d21ed4d144 174 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 150 166 1.7E-18 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CDC59_RS12645 dc728ee48f8f65e0763675d21ed4d144 174 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 67 75 1.7E-18 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CDC59_RS12645 dc728ee48f8f65e0763675d21ed4d144 174 TIGRFAM TIGR00077 lspA: signal peptidase II 29 170 2.7E-43 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CDC59_RS12645 dc728ee48f8f65e0763675d21ed4d144 174 ProSitePatterns PS00855 Signal peptidases II signature. 117 129 - T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CDC59_RS12645 dc728ee48f8f65e0763675d21ed4d144 174 Pfam PF01252 Signal peptidase (SPase) II 30 169 9.5E-42 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CDC59_RS06175 6beca23c4f27345bb9026e4230bc882b 272 Pfam PF00753 Metallo-beta-lactamase superfamily 28 221 4.9E-19 T 29-03-2018 IPR001279 Metallo-beta-lactamase CDC59_RS06175 6beca23c4f27345bb9026e4230bc882b 272 Gene3D G3DSA:3.60.15.10 23 242 3.0E-23 T 29-03-2018 IPR001279 Metallo-beta-lactamase CDC59_RS06175 6beca23c4f27345bb9026e4230bc882b 272 SMART SM00849 29 221 3.7E-12 T 29-03-2018 IPR001279 Metallo-beta-lactamase CDC59_RS06175 6beca23c4f27345bb9026e4230bc882b 272 SUPERFAMILY SSF56281 29 243 1.15E-27 T 29-03-2018 IPR001279 Metallo-beta-lactamase CDC59_RS11745 b869cd9dbe5e16d0e91f751796e612ef 490 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 6 475 2.5E-136 T 29-03-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 CDC59_RS11745 b869cd9dbe5e16d0e91f751796e612ef 490 Pfam PF00361 Proton-conducting membrane transporter 125 423 1.9E-72 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS11745 b869cd9dbe5e16d0e91f751796e612ef 490 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 4 477 18.039 T 29-03-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 CDC59_RS11745 b869cd9dbe5e16d0e91f751796e612ef 490 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 215 236 1.4E-5 T 29-03-2018 CDC59_RS11745 b869cd9dbe5e16d0e91f751796e612ef 490 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 72 97 1.4E-5 T 29-03-2018 CDC59_RS11745 b869cd9dbe5e16d0e91f751796e612ef 490 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 420 439 1.4E-5 T 29-03-2018 CDC59_RS11745 b869cd9dbe5e16d0e91f751796e612ef 490 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 307 319 1.4E-5 T 29-03-2018 CDC59_RS14910 826162f2b50ac69e751f9b3804e4436f 363 SMART SM00849 42 274 3.7E-19 T 29-03-2018 IPR001279 Metallo-beta-lactamase CDC59_RS14910 826162f2b50ac69e751f9b3804e4436f 363 Pfam PF00753 Metallo-beta-lactamase superfamily 41 274 7.4E-21 T 29-03-2018 IPR001279 Metallo-beta-lactamase CDC59_RS14910 826162f2b50ac69e751f9b3804e4436f 363 Gene3D G3DSA:3.60.15.10 15 296 8.0E-38 T 29-03-2018 IPR001279 Metallo-beta-lactamase CDC59_RS14910 826162f2b50ac69e751f9b3804e4436f 363 SUPERFAMILY SSF56281 25 359 1.05E-66 T 29-03-2018 IPR001279 Metallo-beta-lactamase CDC59_RS00845 ca6918ce052e9eb01306fed3cd0bbf73 291 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 1 291 6.9E-105 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS00845 ca6918ce052e9eb01306fed3cd0bbf73 291 Gene3D G3DSA:3.40.1380.10 27 242 5.0E-73 T 29-03-2018 CDC59_RS00845 ca6918ce052e9eb01306fed3cd0bbf73 291 SUPERFAMILY SSF52943 2 291 1.57E-94 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS00845 ca6918ce052e9eb01306fed3cd0bbf73 291 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 291 36.187 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS00845 ca6918ce052e9eb01306fed3cd0bbf73 291 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 277 290 - T 29-03-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS00845 ca6918ce052e9eb01306fed3cd0bbf73 291 Gene3D G3DSA:1.10.287.80 243 286 7.6E-13 T 29-03-2018 CDC59_RS00845 ca6918ce052e9eb01306fed3cd0bbf73 291 PRINTS PR00126 ATP synthase gamma subunit signature 73 92 1.3E-36 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS00845 ca6918ce052e9eb01306fed3cd0bbf73 291 PRINTS PR00126 ATP synthase gamma subunit signature 166 183 1.3E-36 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS00845 ca6918ce052e9eb01306fed3cd0bbf73 291 PRINTS PR00126 ATP synthase gamma subunit signature 238 257 1.3E-36 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS00845 ca6918ce052e9eb01306fed3cd0bbf73 291 PRINTS PR00126 ATP synthase gamma subunit signature 269 290 1.3E-36 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS00845 ca6918ce052e9eb01306fed3cd0bbf73 291 Pfam PF00231 ATP synthase 4 290 8.1E-95 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CDC59_RS08245 d61f5ebcb009182aedb0e62fe5829543 319 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 13 311 7.0E-98 T 29-03-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 CDC59_RS08245 d61f5ebcb009182aedb0e62fe5829543 319 Hamap MF_00492 Transaldolase [tal]. 1 316 50.57 T 29-03-2018 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 CDC59_RS08245 d61f5ebcb009182aedb0e62fe5829543 319 ProSitePatterns PS01054 Transaldolase signature 1. 30 38 - T 29-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 CDC59_RS08245 d61f5ebcb009182aedb0e62fe5829543 319 Gene3D G3DSA:3.20.20.70 1 314 1.6E-116 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS08245 d61f5ebcb009182aedb0e62fe5829543 319 TIGRFAM TIGR00874 talAB: transaldolase 2 313 7.2E-140 T 29-03-2018 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 CDC59_RS08245 d61f5ebcb009182aedb0e62fe5829543 319 SUPERFAMILY SSF51569 1 314 1.88E-113 T 29-03-2018 CDC59_RS14820 99747ece0276afe542b68ad23e05752f 378 Pfam PF11306 Protein of unknown function (DUF3108) 119 359 2.0E-20 T 29-03-2018 IPR021457 Protein of unknown function DUF3108 CDC59_RS21470 67ae34e09ef8ee34cafdb9bf2f152cee 439 Gene3D G3DSA:3.40.50.2300 16 153 2.7E-8 T 29-03-2018 CDC59_RS21470 67ae34e09ef8ee34cafdb9bf2f152cee 439 Gene3D G3DSA:3.40.50.300 154 393 3.0E-36 T 29-03-2018 CDC59_RS21470 67ae34e09ef8ee34cafdb9bf2f152cee 439 SUPERFAMILY SSF52540 154 391 3.12E-30 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS05350 67f0660586b5ea3c66cc6853512f49a7 351 PIRSF PIRSF004440 2 345 1.3E-41 T 29-03-2018 IPR026276 Baseplate protein GpP CDC59_RS05350 67f0660586b5ea3c66cc6853512f49a7 351 SUPERFAMILY SSF69279 7 172 4.19E-28 T 29-03-2018 CDC59_RS05350 67f0660586b5ea3c66cc6853512f49a7 351 SUPERFAMILY SSF69279 160 333 1.26E-35 T 29-03-2018 CDC59_RS05350 67f0660586b5ea3c66cc6853512f49a7 351 Gene3D G3DSA:2.30.300.10 182 346 3.0E-17 T 29-03-2018 CDC59_RS05350 67f0660586b5ea3c66cc6853512f49a7 351 Gene3D G3DSA:2.30.300.10 2 181 3.4E-26 T 29-03-2018 CDC59_RS06290 8c90383b530ce7c467d4aff7cd4cdebe 529 Pfam PF05872 Bacterial protein of unknown function (DUF853) 5 528 2.7E-250 T 29-03-2018 IPR033186 Helicase HerA-like C-terminal CDC59_RS06290 8c90383b530ce7c467d4aff7cd4cdebe 529 SUPERFAMILY SSF52540 12 368 8.57E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS06290 8c90383b530ce7c467d4aff7cd4cdebe 529 Gene3D G3DSA:3.40.50.300 3 343 2.2E-28 T 29-03-2018 CDC59_RS16760 05ada2de0f0b019373c262247e64c4fb 494 SUPERFAMILY SSF56954 74 483 3.01E-84 T 29-03-2018 CDC59_RS16760 05ada2de0f0b019373c262247e64c4fb 494 PIRSF PIRSF001892 17 490 1.6E-118 T 29-03-2018 IPR028351 Cyclolysin transport protein CyaE GO:0005215 CDC59_RS16760 05ada2de0f0b019373c262247e64c4fb 494 Gene3D G3DSA:1.20.1600.10 75 487 5.5E-78 T 29-03-2018 CDC59_RS16760 05ada2de0f0b019373c262247e64c4fb 494 Pfam PF02321 Outer membrane efflux protein 295 481 5.9E-34 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CDC59_RS16760 05ada2de0f0b019373c262247e64c4fb 494 Pfam PF02321 Outer membrane efflux protein 83 271 3.4E-33 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CDC59_RS16140 1c90ddfd5f93870ed49d6dde78d1586e 758 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 279 723 1.0E-68 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS16140 1c90ddfd5f93870ed49d6dde78d1586e 758 Gene3D G3DSA:1.20.210.10 269 742 5.2E-62 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS16140 1c90ddfd5f93870ed49d6dde78d1586e 758 SUPERFAMILY SSF81442 274 747 1.44E-80 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS16550 235b10501d478f37deb46031edbbdd0b 391 PRINTS PR00812 Bacterial general secretion pathway protein F signature 153 181 6.0E-16 T 29-03-2018 IPR003004 GspF/PilC family CDC59_RS16550 235b10501d478f37deb46031edbbdd0b 391 PRINTS PR00812 Bacterial general secretion pathway protein F signature 54 66 6.0E-16 T 29-03-2018 IPR003004 GspF/PilC family CDC59_RS16550 235b10501d478f37deb46031edbbdd0b 391 PRINTS PR00812 Bacterial general secretion pathway protein F signature 371 390 6.0E-16 T 29-03-2018 IPR003004 GspF/PilC family CDC59_RS16550 235b10501d478f37deb46031edbbdd0b 391 PRINTS PR00812 Bacterial general secretion pathway protein F signature 355 369 6.0E-16 T 29-03-2018 IPR003004 GspF/PilC family CDC59_RS16550 235b10501d478f37deb46031edbbdd0b 391 Pfam PF00482 Type II secretion system (T2SS), protein F 261 382 3.3E-22 T 29-03-2018 IPR018076 Type II secretion system F domain CDC59_RS16550 235b10501d478f37deb46031edbbdd0b 391 Pfam PF00482 Type II secretion system (T2SS), protein F 58 181 5.9E-28 T 29-03-2018 IPR018076 Type II secretion system F domain CDC59_RS22070 209bd338afaa4c727cd63657e9ce12a0 324 SUPERFAMILY SSF51679 28 321 1.53E-65 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CDC59_RS22070 209bd338afaa4c727cd63657e9ce12a0 324 Gene3D G3DSA:3.20.20.30 6 322 3.2E-64 T 29-03-2018 CDC59_RS22070 209bd338afaa4c727cd63657e9ce12a0 324 Pfam PF00296 Luciferase-like monooxygenase 38 266 3.0E-41 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CDC59_RS17045 bc9777af0b6c86ab7ecb5862b870e306 362 Pfam PF10135 Rod binding protein 49 95 5.8E-16 T 29-03-2018 IPR019301 Flagellar protein FlgJ, N-terminal CDC59_RS17045 bc9777af0b6c86ab7ecb5862b870e306 362 PRINTS PR01002 Flagellar protein FlgJ signature 27 50 9.0E-12 T 29-03-2018 CDC59_RS17045 bc9777af0b6c86ab7ecb5862b870e306 362 PRINTS PR01002 Flagellar protein FlgJ signature 52 72 9.0E-12 T 29-03-2018 CDC59_RS17045 bc9777af0b6c86ab7ecb5862b870e306 362 PRINTS PR01002 Flagellar protein FlgJ signature 5 25 9.0E-12 T 29-03-2018 CDC59_RS17045 bc9777af0b6c86ab7ecb5862b870e306 362 Gene3D G3DSA:1.10.530.10 208 362 5.3E-35 T 29-03-2018 CDC59_RS17045 bc9777af0b6c86ab7ecb5862b870e306 362 TIGRFAM TIGR02541 flagell_FlgJ: flagellar rod assembly protein/muramidase FlgJ 11 361 2.2E-97 T 29-03-2018 IPR013377 Peptidoglycan hydrolase FlgJ GO:0016798|GO:0044780 CDC59_RS17045 bc9777af0b6c86ab7ecb5862b870e306 362 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 222 361 1.5E-20 T 29-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CDC59_RS17045 bc9777af0b6c86ab7ecb5862b870e306 362 SMART SM00047 201 362 3.3E-37 T 29-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CDC59_RS10450 5618968359aa9b8ff65784bcdc7758e1 235 Pfam PF00881 Nitroreductase family 18 210 1.6E-38 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CDC59_RS10450 5618968359aa9b8ff65784bcdc7758e1 235 Gene3D G3DSA:3.40.109.10 1 231 1.1E-57 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CDC59_RS10450 5618968359aa9b8ff65784bcdc7758e1 235 SUPERFAMILY SSF55469 15 233 1.02E-52 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CDC59_RS10695 85bd5798541512e3b6c44bbb9521c0a3 118 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 30.191 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS10695 85bd5798541512e3b6c44bbb9521c0a3 118 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 5.3E-50 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS10695 85bd5798541512e3b6c44bbb9521c0a3 118 Gene3D G3DSA:1.10.1900.20 55 116 7.6E-30 T 29-03-2018 IPR035566 Ribosomal protein L20 C-terminal domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS10695 85bd5798541512e3b6c44bbb9521c0a3 118 Pfam PF00453 Ribosomal protein L20 3 109 1.0E-49 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS10695 85bd5798541512e3b6c44bbb9521c0a3 118 PRINTS PR00062 Ribosomal protein L20 signature 42 71 5.1E-40 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS10695 85bd5798541512e3b6c44bbb9521c0a3 118 PRINTS PR00062 Ribosomal protein L20 signature 12 41 5.1E-40 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS10695 85bd5798541512e3b6c44bbb9521c0a3 118 PRINTS PR00062 Ribosomal protein L20 signature 75 101 5.1E-40 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS10695 85bd5798541512e3b6c44bbb9521c0a3 118 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS10695 85bd5798541512e3b6c44bbb9521c0a3 118 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 72 1.0E-22 T 29-03-2018 CDC59_RS10695 85bd5798541512e3b6c44bbb9521c0a3 118 SUPERFAMILY SSF74731 2 115 5.89E-50 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS20500 008f14075a14b8083620b3fc326cad35 1352 Pfam PF04261 Dyp-type peroxidase family 157 394 8.8E-13 T 29-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 CDC59_RS20500 008f14075a14b8083620b3fc326cad35 1352 SUPERFAMILY SSF54909 52 398 3.4E-37 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CDC59_RS20500 008f14075a14b8083620b3fc326cad35 1352 Gene3D G3DSA:3.20.70.20 592 1352 4.5E-144 T 29-03-2018 CDC59_RS20500 008f14075a14b8083620b3fc326cad35 1352 SUPERFAMILY SSF51998 592 1343 3.07E-97 T 29-03-2018 CDC59_RS20500 008f14075a14b8083620b3fc326cad35 1352 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 55 396 8.6E-71 T 29-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 CDC59_RS20500 008f14075a14b8083620b3fc326cad35 1352 Pfam PF02901 Pyruvate formate lyase-like 597 1185 5.0E-135 T 29-03-2018 IPR004184 Pyruvate formate lyase domain GO:0003824 CDC59_RS22445 3957158cf2b35c5a7ef91480b223a443 200 Gene3D G3DSA:1.10.760.10 61 187 1.5E-24 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS22445 3957158cf2b35c5a7ef91480b223a443 200 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 76 158 2.3E-12 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS22445 3957158cf2b35c5a7ef91480b223a443 200 SUPERFAMILY SSF46626 76 188 2.01E-27 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS19455 231d6a9ba2763de2aaa24095597b9a11 294 Gene3D G3DSA:1.10.10.10 11 89 8.4E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS19455 231d6a9ba2763de2aaa24095597b9a11 294 Pfam PF01614 Bacterial transcriptional regulator 149 242 1.8E-4 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CDC59_RS19455 231d6a9ba2763de2aaa24095597b9a11 294 Pfam PF09339 IclR helix-turn-helix domain 30 81 1.5E-14 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CDC59_RS19455 231d6a9ba2763de2aaa24095597b9a11 294 Gene3D G3DSA:3.30.450.40 101 279 5.8E-31 T 29-03-2018 IPR029016 GAF domain-like CDC59_RS19455 231d6a9ba2763de2aaa24095597b9a11 294 SUPERFAMILY SSF55781 94 275 1.05E-26 T 29-03-2018 IPR029016 GAF domain-like CDC59_RS19455 231d6a9ba2763de2aaa24095597b9a11 294 SUPERFAMILY SSF46785 28 102 3.1E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS19455 231d6a9ba2763de2aaa24095597b9a11 294 SMART SM00346 28 118 6.7E-18 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CDC59_RS15185 63330bb2989342a9c8dd7eb625360b46 406 ProSitePatterns PS01288 Uncharacterized protein family UPF0027 signature. 33 62 - T 29-03-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 CDC59_RS15185 63330bb2989342a9c8dd7eb625360b46 406 SUPERFAMILY SSF103365 6 406 4.18E-141 T 29-03-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 CDC59_RS15185 63330bb2989342a9c8dd7eb625360b46 406 Pfam PF01139 tRNA-splicing ligase RtcB 33 406 6.5E-133 T 29-03-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 CDC59_RS19725 2ea4e6978e932f009ae224b783685ea0 359 Pfam PF06812 ImpA, N-terminal, type VI secretion system 10 132 3.9E-38 T 29-03-2018 IPR010657 ImpA, N-terminal CDC59_RS19725 2ea4e6978e932f009ae224b783685ea0 359 TIGRFAM TIGR03363 VI_chp_8: type VI secretion-associated protein, ImpA family 5 349 2.2E-117 T 29-03-2018 IPR017740 Type VI secretion system-associated, ImpA CDC59_RS15035 339b1a102e361a39406304a51b602a58 88 Pfam PF06945 Protein of unknown function (DUF1289) 31 77 3.4E-21 T 29-03-2018 IPR010710 Protein of unknown function DUF1289 CDC59_RS06295 d7c33f0e7d012727a578ba3450445f16 216 Pfam PF14681 Uracil phosphoribosyltransferase 13 214 2.3E-70 T 29-03-2018 CDC59_RS06295 d7c33f0e7d012727a578ba3450445f16 216 SUPERFAMILY SSF53271 11 213 5.68E-61 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CDC59_RS06295 d7c33f0e7d012727a578ba3450445f16 216 Gene3D G3DSA:3.40.50.2020 9 213 4.0E-59 T 29-03-2018 CDC59_RS06295 d7c33f0e7d012727a578ba3450445f16 216 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 12 215 2.6E-76 T 29-03-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CDC59_RS06295 d7c33f0e7d012727a578ba3450445f16 216 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 9 215 43.562 T 29-03-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CDC59_RS06790 f48aa1ffa46ed4650f9114b92b74bb53 264 PRINTS PR00108 Thymidylate synthase family signature 42 63 2.6E-47 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CDC59_RS06790 f48aa1ffa46ed4650f9114b92b74bb53 264 PRINTS PR00108 Thymidylate synthase family signature 115 134 2.6E-47 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CDC59_RS06790 f48aa1ffa46ed4650f9114b92b74bb53 264 PRINTS PR00108 Thymidylate synthase family signature 197 214 2.6E-47 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CDC59_RS06790 f48aa1ffa46ed4650f9114b92b74bb53 264 PRINTS PR00108 Thymidylate synthase family signature 141 156 2.6E-47 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CDC59_RS06790 f48aa1ffa46ed4650f9114b92b74bb53 264 PRINTS PR00108 Thymidylate synthase family signature 159 185 2.6E-47 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CDC59_RS06790 f48aa1ffa46ed4650f9114b92b74bb53 264 Hamap MF_00008 Thymidylate synthase [thyA]. 1 264 39.733 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CDC59_RS06790 f48aa1ffa46ed4650f9114b92b74bb53 264 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 85 264 3.9E-96 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CDC59_RS06790 f48aa1ffa46ed4650f9114b92b74bb53 264 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 3 84 1.9E-40 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CDC59_RS06790 f48aa1ffa46ed4650f9114b92b74bb53 264 Pfam PF00303 Thymidylate synthase 3 264 3.2E-126 T 29-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CDC59_RS06790 f48aa1ffa46ed4650f9114b92b74bb53 264 Gene3D G3DSA:3.30.572.10 1 264 1.1E-132 T 29-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CDC59_RS06790 f48aa1ffa46ed4650f9114b92b74bb53 264 SUPERFAMILY SSF55831 1 264 2.49E-129 T 29-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CDC59_RS06790 f48aa1ffa46ed4650f9114b92b74bb53 264 ProSitePatterns PS00091 Thymidylate synthase active site. 126 154 - T 29-03-2018 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CDC59_RS04630 ca52368bc4f3c1493172def9a6c00498 165 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 14 148 3.7E-48 T 29-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CDC59_RS04630 ca52368bc4f3c1493172def9a6c00498 165 Gene3D G3DSA:3.40.50.960 7 152 1.9E-52 T 29-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CDC59_RS04630 ca52368bc4f3c1493172def9a6c00498 165 SUPERFAMILY SSF52121 6 151 9.81E-52 T 29-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CDC59_RS04630 ca52368bc4f3c1493172def9a6c00498 165 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 15 147 3.2E-38 T 29-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CDC59_RS04630 ca52368bc4f3c1493172def9a6c00498 165 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 10 151 26.894 T 29-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CDC59_RS19140 5aff3d98de40d53520ef40ce37d26e9b 227 SUPERFAMILY SSF161098 14 208 1.31E-31 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS19140 5aff3d98de40d53520ef40ce37d26e9b 227 Gene3D G3DSA:1.10.3720.10 11 226 3.9E-30 T 29-03-2018 CDC59_RS19140 5aff3d98de40d53520ef40ce37d26e9b 227 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 14 116 5.3E-17 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CDC59_RS19140 5aff3d98de40d53520ef40ce37d26e9b 227 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 208 2.6E-12 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS04465 af49e91afb8e2fa6e34027b23bd5aee8 354 SUPERFAMILY SSF51735 3 336 2.23E-91 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS04465 af49e91afb8e2fa6e34027b23bd5aee8 354 Pfam PF16363 GDP-mannose 4,6 dehydratase 5 325 1.0E-99 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS04465 af49e91afb8e2fa6e34027b23bd5aee8 354 Gene3D G3DSA:3.40.50.720 2 195 1.7E-37 T 29-03-2018 CDC59_RS04465 af49e91afb8e2fa6e34027b23bd5aee8 354 Gene3D G3DSA:3.90.25.10 196 354 4.2E-51 T 29-03-2018 CDC59_RS04465 af49e91afb8e2fa6e34027b23bd5aee8 354 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 4 338 4.9E-155 T 29-03-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 CDC59_RS22560 767c0006801b34bfc31e2c1a48852fc0 298 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 47 271 2.0E-53 T 29-03-2018 IPR018713 Domain of unknown function DUF2236 CDC59_RS23450 c3aad889dfe0a89278ebc064631896a7 94 Gene3D G3DSA:1.10.10.10 14 74 5.4E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS23450 c3aad889dfe0a89278ebc064631896a7 94 SUPERFAMILY SSF46955 14 69 6.41E-8 T 29-03-2018 IPR009061 Putative DNA-binding domain CDC59_RS21635 e39b96bdf7dcc4788817312062541b3b 473 Gene3D G3DSA:3.90.79.10 156 328 8.5E-6 T 29-03-2018 CDC59_RS21635 e39b96bdf7dcc4788817312062541b3b 473 ProSitePatterns PS00893 Nudix box signature. 201 222 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CDC59_RS21635 e39b96bdf7dcc4788817312062541b3b 473 SUPERFAMILY SSF55811 184 238 3.79E-5 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CDC59_RS23950 471a723720952d916b3af2a8a71c6e08 286 Gene3D G3DSA:3.40.190.10 1 211 3.8E-5 T 29-03-2018 CDC59_RS15320 a8d268e755924cbf25946e9b917374c8 427 Pfam PF01593 Flavin containing amine oxidoreductase 15 358 3.8E-29 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 CDC59_RS15320 a8d268e755924cbf25946e9b917374c8 427 PRINTS PR00419 Adrenodoxin reductase family signature 28 41 1.8E-7 T 29-03-2018 CDC59_RS15320 a8d268e755924cbf25946e9b917374c8 427 PRINTS PR00419 Adrenodoxin reductase family signature 5 27 1.8E-7 T 29-03-2018 CDC59_RS15320 a8d268e755924cbf25946e9b917374c8 427 Gene3D G3DSA:3.50.50.60 2 407 6.9E-29 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS15320 a8d268e755924cbf25946e9b917374c8 427 SUPERFAMILY SSF51905 5 294 4.26E-46 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS15320 a8d268e755924cbf25946e9b917374c8 427 SUPERFAMILY SSF51905 393 425 4.26E-46 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS23290 b5b9d890617f58f4d3f6cac7887a8b73 1366 TIGRFAM TIGR02675 tape_meas_nterm: tape measure domain 157 231 2.6E-20 T 29-03-2018 IPR013491 Caudovirus, tape measure, N-terminal CDC59_RS14555 0a2eed3098632d3df95139cc4f3c3ae2 431 Pfam PF08886 Glutamate-cysteine ligase 17 422 1.7E-201 T 29-03-2018 IPR011718 Glutamate--cysteine ligase GshA CDC59_RS14555 0a2eed3098632d3df95139cc4f3c3ae2 431 Gene3D G3DSA:3.30.470.20 245 382 0.002 T 29-03-2018 CDC59_RS14555 0a2eed3098632d3df95139cc4f3c3ae2 431 TIGRFAM TIGR02049 gshA_ferroox: glutamate--cysteine ligase 17 425 2.9E-216 T 29-03-2018 IPR011718 Glutamate--cysteine ligase GshA CDC59_RS03340 db77b0fc2c0dfe40d5830113c5719bb9 360 Gene3D G3DSA:3.40.630.10 17 297 5.9E-19 T 29-03-2018 CDC59_RS03340 db77b0fc2c0dfe40d5830113c5719bb9 360 Pfam PF10994 Protein of unknown function (DUF2817) 7 345 1.5E-127 T 29-03-2018 IPR021259 Protein of unknown function DUF2817 CDC59_RS03340 db77b0fc2c0dfe40d5830113c5719bb9 360 SUPERFAMILY SSF53187 186 311 1.61E-20 T 29-03-2018 CDC59_RS03340 db77b0fc2c0dfe40d5830113c5719bb9 360 SUPERFAMILY SSF53187 54 127 1.61E-20 T 29-03-2018 CDC59_RS05435 2dbdf635f212e809a5d2a8eb133bd5df 239 SUPERFAMILY SSF53335 14 235 3.05E-47 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS05435 2dbdf635f212e809a5d2a8eb133bd5df 239 Hamap MF_00472 Ubiquinone biosynthesis O-methyltransferase [ubiG]. 10 235 38.741 T 29-03-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|KEGG: 00340+2.1.1.22|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 CDC59_RS05435 2dbdf635f212e809a5d2a8eb133bd5df 239 TIGRFAM TIGR01983 UbiG: 3-demethylubiquinone-9 3-O-methyltransferase 12 229 4.6E-83 T 29-03-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|KEGG: 00340+2.1.1.22|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 CDC59_RS05435 2dbdf635f212e809a5d2a8eb133bd5df 239 Pfam PF13489 Methyltransferase domain 50 203 2.0E-24 T 29-03-2018 CDC59_RS05435 2dbdf635f212e809a5d2a8eb133bd5df 239 Gene3D G3DSA:3.40.50.150 2 235 9.1E-49 T 29-03-2018 CDC59_RS03755 04ed056e4905645db8d10f46c63759ba 376 SMART SM01119 254 362 4.0E-43 T 29-03-2018 IPR026956 D-serine dehydratase-like domain CDC59_RS03755 04ed056e4905645db8d10f46c63759ba 376 SUPERFAMILY SSF51419 13 247 3.76E-36 T 29-03-2018 IPR029066 PLP-binding barrel CDC59_RS03755 04ed056e4905645db8d10f46c63759ba 376 Gene3D G3DSA:3.20.20.10 15 236 1.2E-43 T 29-03-2018 IPR029066 PLP-binding barrel CDC59_RS03755 04ed056e4905645db8d10f46c63759ba 376 Pfam PF01168 Alanine racemase, N-terminal domain 13 237 1.3E-32 T 29-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CDC59_RS03755 04ed056e4905645db8d10f46c63759ba 376 Pfam PF14031 Putative serine dehydratase domain 254 359 2.7E-21 T 29-03-2018 IPR026956 D-serine dehydratase-like domain CDC59_RS11710 c883e2288fb5f0d057792e3733293a58 162 Pfam PF01575 MaoC like domain 14 117 5.0E-25 T 29-03-2018 IPR002539 MaoC-like domain CDC59_RS11710 c883e2288fb5f0d057792e3733293a58 162 Gene3D G3DSA:3.10.129.10 1 162 4.5E-38 T 29-03-2018 CDC59_RS11710 c883e2288fb5f0d057792e3733293a58 162 SUPERFAMILY SSF54637 7 158 4.42E-36 T 29-03-2018 IPR029069 HotDog domain CDC59_RS14775 297ae6a08b9b41e93d7c5c8b606bf5b3 391 SUPERFAMILY SSF52151 4 273 9.94E-42 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CDC59_RS14775 297ae6a08b9b41e93d7c5c8b606bf5b3 391 Pfam PF01734 Patatin-like phospholipase 7 226 8.9E-23 T 29-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 CDC59_RS14775 297ae6a08b9b41e93d7c5c8b606bf5b3 391 Gene3D G3DSA:3.40.1090.10 2 260 7.0E-35 T 29-03-2018 CDC59_RS01805 d5e0df14536279f55893d25ad62bd99f 264 Pfam PF08874 Domain of unknown function (DUF1835) 4 119 1.5E-27 T 29-03-2018 IPR014973 Protein of unknown function DUF1835 CDC59_RS01805 d5e0df14536279f55893d25ad62bd99f 264 Pfam PF12395 Protein of unknown function 150 253 2.8E-29 T 29-03-2018 IPR022123 Protein of unknown function DUF3658 CDC59_RS04555 7a23aad41f69af1cc1538f6af1ac3f3a 85 Pfam PF03692 Putative zinc- or iron-chelating domain 2 57 1.6E-6 T 29-03-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein CDC59_RS09715 9e6ccd3a2cdf868d0df90dc8cd349d77 210 Pfam PF00857 Isochorismatase family 8 202 3.3E-29 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CDC59_RS09715 9e6ccd3a2cdf868d0df90dc8cd349d77 210 SUPERFAMILY SSF52499 6 207 4.45E-47 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CDC59_RS09715 9e6ccd3a2cdf868d0df90dc8cd349d77 210 Gene3D G3DSA:3.40.50.850 2 209 4.3E-57 T 29-03-2018 CDC59_RS17110 ea05e8f29255fc0dfe7a2d0ceb58ef42 335 TIGRFAM TIGR01397 fliM_switch: flagellar motor switch protein FliM 6 320 4.7E-104 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CDC59_RS17110 ea05e8f29255fc0dfe7a2d0ceb58ef42 335 PRINTS PR00955 Flagellar motor switch protein FliM signature 4 17 3.0E-25 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CDC59_RS17110 ea05e8f29255fc0dfe7a2d0ceb58ef42 335 PRINTS PR00955 Flagellar motor switch protein FliM signature 89 105 3.0E-25 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CDC59_RS17110 ea05e8f29255fc0dfe7a2d0ceb58ef42 335 PRINTS PR00955 Flagellar motor switch protein FliM signature 114 133 3.0E-25 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CDC59_RS17110 ea05e8f29255fc0dfe7a2d0ceb58ef42 335 PRINTS PR00955 Flagellar motor switch protein FliM signature 212 230 3.0E-25 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CDC59_RS17110 ea05e8f29255fc0dfe7a2d0ceb58ef42 335 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 251 320 1.9E-19 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) CDC59_RS17110 ea05e8f29255fc0dfe7a2d0ceb58ef42 335 SUPERFAMILY SSF103039 55 230 1.83E-21 T 29-03-2018 IPR028976 CheC-like domain CDC59_RS17110 ea05e8f29255fc0dfe7a2d0ceb58ef42 335 SUPERFAMILY SSF103039 6 15 1.83E-21 T 29-03-2018 IPR028976 CheC-like domain CDC59_RS17110 ea05e8f29255fc0dfe7a2d0ceb58ef42 335 Pfam PF02154 Flagellar motor switch protein FliM 38 230 3.0E-69 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CDC59_RS17110 ea05e8f29255fc0dfe7a2d0ceb58ef42 335 SUPERFAMILY SSF101801 250 322 2.75E-13 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) CDC59_RS17110 ea05e8f29255fc0dfe7a2d0ceb58ef42 335 Gene3D G3DSA:3.40.1550.10 46 234 1.8E-39 T 29-03-2018 IPR028976 CheC-like domain CDC59_RS17110 ea05e8f29255fc0dfe7a2d0ceb58ef42 335 Gene3D G3DSA:2.30.330.10 239 328 3.5E-16 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) CDC59_RS17110 ea05e8f29255fc0dfe7a2d0ceb58ef42 335 PIRSF PIRSF002888 3 330 1.6E-96 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CDC59_RS06905 4ff690fd005026335a89e51b1f0e8a78 303 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 43 272 1.1E-46 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CDC59_RS06905 4ff690fd005026335a89e51b1f0e8a78 303 Gene3D G3DSA:3.40.190.10 171 303 1.7E-16 T 29-03-2018 CDC59_RS06905 4ff690fd005026335a89e51b1f0e8a78 303 SUPERFAMILY SSF53850 18 275 5.45E-62 T 29-03-2018 CDC59_RS06905 4ff690fd005026335a89e51b1f0e8a78 303 SMART SM00062 42 274 7.4E-51 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CDC59_RS06905 4ff690fd005026335a89e51b1f0e8a78 303 Gene3D G3DSA:3.40.190.10 6 170 6.9E-30 T 29-03-2018 CDC59_RS15805 95b5a6ed7c9a54bf1af32db7c46c5017 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 5.5E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS15805 95b5a6ed7c9a54bf1af32db7c46c5017 312 Pfam PF03466 LysR substrate binding domain 88 293 2.1E-42 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS15805 95b5a6ed7c9a54bf1af32db7c46c5017 312 Gene3D G3DSA:1.10.10.10 3 83 5.8E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS15805 95b5a6ed7c9a54bf1af32db7c46c5017 312 SUPERFAMILY SSF53850 90 294 2.79E-43 T 29-03-2018 CDC59_RS15805 95b5a6ed7c9a54bf1af32db7c46c5017 312 Gene3D G3DSA:3.40.190.10 89 176 1.5E-9 T 29-03-2018 CDC59_RS15805 95b5a6ed7c9a54bf1af32db7c46c5017 312 SUPERFAMILY SSF46785 4 86 6.07E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS15805 95b5a6ed7c9a54bf1af32db7c46c5017 312 Gene3D G3DSA:3.40.190.10 177 265 7.3E-26 T 29-03-2018 CDC59_RS21255 21d221a6a1dcd50c8474dfacc7f81f6b 923 SUPERFAMILY SSF56784 345 383 2.15E-9 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS21255 21d221a6a1dcd50c8474dfacc7f81f6b 923 SUPERFAMILY SSF56784 163 289 2.15E-9 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS21255 21d221a6a1dcd50c8474dfacc7f81f6b 923 Gene3D G3DSA:3.40.50.1000 76 435 2.9E-9 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS11760 71637b11875ee766a75a44b79683a920 101 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 2 101 20.573 T 29-03-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 CDC59_RS11760 71637b11875ee766a75a44b79683a920 101 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 7 96 4.0E-23 T 29-03-2018 CDC59_RS20075 b27cf79acd08639f5360256927d94263 518 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 4 29 3.7E-54 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS20075 b27cf79acd08639f5360256927d94263 518 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 438 467 3.7E-54 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS20075 b27cf79acd08639f5360256927d94263 518 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 390 419 3.7E-54 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS20075 b27cf79acd08639f5360256927d94263 518 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 187 207 3.7E-54 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS20075 b27cf79acd08639f5360256927d94263 518 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 361 388 3.7E-54 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS20075 b27cf79acd08639f5360256927d94263 518 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 284 313 3.7E-54 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS20075 b27cf79acd08639f5360256927d94263 518 Pfam PF12729 Four helix bundle sensory module for signal transduction 4 170 3.3E-16 T 29-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain CDC59_RS20075 b27cf79acd08639f5360256927d94263 518 SUPERFAMILY SSF58104 230 512 2.09E-68 T 29-03-2018 CDC59_RS20075 b27cf79acd08639f5360256927d94263 518 Pfam PF00672 HAMP domain 210 258 5.2E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CDC59_RS20075 b27cf79acd08639f5360256927d94263 518 Gene3D G3DSA:1.10.287.950 24 317 7.5E-16 T 29-03-2018 CDC59_RS20075 b27cf79acd08639f5360256927d94263 518 Gene3D G3DSA:1.10.287.950 318 514 2.3E-46 T 29-03-2018 CDC59_RS20075 b27cf79acd08639f5360256927d94263 518 SMART SM00304 210 262 2.1E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CDC59_RS20075 b27cf79acd08639f5360256927d94263 518 SMART SM00283 263 510 1.7E-79 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CDC59_RS20075 b27cf79acd08639f5360256927d94263 518 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 322 478 5.8E-43 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CDC59_RS21030 64ce32ff49ec6ab1dda61739c132458c 295 Pfam PF13673 Acetyltransferase (GNAT) domain 43 140 7.6E-12 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CDC59_RS21030 64ce32ff49ec6ab1dda61739c132458c 295 Gene3D G3DSA:3.40.630.30 3 133 4.2E-25 T 29-03-2018 CDC59_RS21030 64ce32ff49ec6ab1dda61739c132458c 295 Gene3D G3DSA:3.40.630.30 134 272 3.3E-8 T 29-03-2018 CDC59_RS21030 64ce32ff49ec6ab1dda61739c132458c 295 SUPERFAMILY SSF55729 16 273 6.15E-41 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDC59_RS16995 a995dc6a00e026854b31ef68af1a9be9 106 Pfam PF04316 Anti-sigma-28 factor, FlgM 52 92 1.2E-8 T 29-03-2018 IPR031316 Anti-sigma-28 factor FlgM, C-terminal CDC59_RS16995 a995dc6a00e026854b31ef68af1a9be9 106 Gene3D G3DSA:1.10.287.1160 65 92 4.7E-10 T 29-03-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 CDC59_RS16995 a995dc6a00e026854b31ef68af1a9be9 106 TIGRFAM TIGR03824 FlgM_jcvi: flagellar biosynthesis anti-sigma factor FlgM 2 95 5.2E-16 T 29-03-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 CDC59_RS16995 a995dc6a00e026854b31ef68af1a9be9 106 SUPERFAMILY SSF101498 28 93 2.75E-10 T 29-03-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 CDC59_RS20725 60b83146b2f6b83f01bae12f7f5d826e 119 Pfam PF11162 Protein of unknown function (DUF2946) 3 116 1.3E-10 T 29-03-2018 IPR021333 Protein of unknown function DUF2946 CDC59_RS17290 cd950f9d5ee13934f189dbe6db6bb03d 341 Pfam PF01594 AI-2E family transporter 19 332 1.4E-13 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like CDC59_RS01095 65926e52c17e869e9d0275f9c28ca722 229 SUPERFAMILY SSF48008 80 211 7.06E-25 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CDC59_RS01095 65926e52c17e869e9d0275f9c28ca722 229 SUPERFAMILY SSF46785 13 91 1.78E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS01095 65926e52c17e869e9d0275f9c28ca722 229 Gene3D G3DSA:1.10.10.10 2 76 1.5E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS01095 65926e52c17e869e9d0275f9c28ca722 229 SMART SM00345 15 73 3.2E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDC59_RS01095 65926e52c17e869e9d0275f9c28ca722 229 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 73 1.7E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDC59_RS01095 65926e52c17e869e9d0275f9c28ca722 229 SMART SM00895 83 206 1.8E-17 T 29-03-2018 IPR011711 GntR, C-terminal CDC59_RS01095 65926e52c17e869e9d0275f9c28ca722 229 Pfam PF07729 FCD domain 83 205 4.0E-23 T 29-03-2018 IPR011711 GntR, C-terminal CDC59_RS01095 65926e52c17e869e9d0275f9c28ca722 229 Gene3D G3DSA:1.20.120.530 77 217 2.0E-28 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CDC59_RS12155 9f3f1430a4e05a7201f14df8d76004fc 988 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 241 257 7.8E-54 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CDC59_RS12155 9f3f1430a4e05a7201f14df8d76004fc 988 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 305 320 7.8E-54 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CDC59_RS12155 9f3f1430a4e05a7201f14df8d76004fc 988 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 189 202 7.8E-54 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CDC59_RS12155 9f3f1430a4e05a7201f14df8d76004fc 988 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 456 476 7.8E-54 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CDC59_RS12155 9f3f1430a4e05a7201f14df8d76004fc 988 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 668 697 7.8E-54 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CDC59_RS12155 9f3f1430a4e05a7201f14df8d76004fc 988 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 626 646 7.8E-54 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CDC59_RS12155 9f3f1430a4e05a7201f14df8d76004fc 988 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 807 833 7.8E-54 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CDC59_RS12155 9f3f1430a4e05a7201f14df8d76004fc 988 Hamap MF_00595 Phosphoenolpyruvate carboxylase [ppc]. 52 988 19.525 T 29-03-2018 IPR022805 Phosphoenolpyruvate carboxylase, bacterial/plant-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CDC59_RS12155 9f3f1430a4e05a7201f14df8d76004fc 988 ProSitePatterns PS00393 Phosphoenolpyruvate carboxylase active site 2. 628 640 - T 29-03-2018 IPR033129 Phosphoenolpyruvate carboxylase, His active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CDC59_RS12155 9f3f1430a4e05a7201f14df8d76004fc 988 ProSitePatterns PS00781 Phosphoenolpyruvate carboxylase active site 1. 190 201 - T 29-03-2018 IPR018129 Phosphoenolpyruvate carboxylase, Lys active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CDC59_RS12155 9f3f1430a4e05a7201f14df8d76004fc 988 Pfam PF00311 Phosphoenolpyruvate carboxylase 187 988 2.4E-296 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CDC59_RS12155 9f3f1430a4e05a7201f14df8d76004fc 988 Gene3D G3DSA:1.20.1440.90 335 458 5.0E-30 T 29-03-2018 CDC59_RS12155 9f3f1430a4e05a7201f14df8d76004fc 988 SUPERFAMILY SSF51621 61 988 0.0 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CDC59_RS17985 c5edb7ae375a4f35f2baa8e483ce1f08 572 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 462 479 1.9E-80 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CDC59_RS17985 c5edb7ae375a4f35f2baa8e483ce1f08 572 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 128 146 1.9E-80 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CDC59_RS17985 c5edb7ae375a4f35f2baa8e483ce1f08 572 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 274 293 1.9E-80 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CDC59_RS17985 c5edb7ae375a4f35f2baa8e483ce1f08 572 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 55 80 1.9E-80 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CDC59_RS17985 c5edb7ae375a4f35f2baa8e483ce1f08 572 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 373 391 1.9E-80 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CDC59_RS17985 c5edb7ae375a4f35f2baa8e483ce1f08 572 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 397 415 1.9E-80 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CDC59_RS17985 c5edb7ae375a4f35f2baa8e483ce1f08 572 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 438 453 1.9E-80 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CDC59_RS17985 c5edb7ae375a4f35f2baa8e483ce1f08 572 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 146 165 1.9E-80 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CDC59_RS17985 c5edb7ae375a4f35f2baa8e483ce1f08 572 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 244 260 1.9E-80 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CDC59_RS17985 c5edb7ae375a4f35f2baa8e483ce1f08 572 ProSitePatterns PS00462 Gamma-glutamyltranspeptidase signature. 373 397 - T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CDC59_RS17985 c5edb7ae375a4f35f2baa8e483ce1f08 572 SUPERFAMILY SSF56235 25 572 1.08E-180 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CDC59_RS17985 c5edb7ae375a4f35f2baa8e483ce1f08 572 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 33 534 2.3E-170 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CDC59_RS17985 c5edb7ae375a4f35f2baa8e483ce1f08 572 Pfam PF01019 Gamma-glutamyltranspeptidase 48 565 9.3E-181 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CDC59_RS22380 9863b4232931ad41cf8092804bc6b40e 210 Pfam PF01810 LysE type translocator 17 203 6.0E-17 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CDC59_RS05275 b140d4ccd1601f2172309e86d434cede 151 Pfam PF06252 Protein of unknown function (DUF1018) 27 150 8.2E-11 T 29-03-2018 IPR009363 Bacteriophage Mu, Gp16 CDC59_RS14130 8f2ce57ddb571ff0ce011703c8ac9e77 173 Gene3D G3DSA:3.10.129.10 2 153 8.0E-34 T 29-03-2018 CDC59_RS14130 8f2ce57ddb571ff0ce011703c8ac9e77 173 SUPERFAMILY SSF54637 18 152 6.41E-16 T 29-03-2018 IPR029069 HotDog domain CDC59_RS01665 2688c500e91f91deea49339636bb8063 488 SUPERFAMILY SSF53383 118 483 3.69E-86 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS01665 2688c500e91f91deea49339636bb8063 488 Gene3D G3DSA:3.90.1150.10 386 486 6.6E-21 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS01665 2688c500e91f91deea49339636bb8063 488 Pfam PF00392 Bacterial regulatory proteins, gntR family 26 84 1.5E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDC59_RS01665 2688c500e91f91deea49339636bb8063 488 SUPERFAMILY SSF46785 20 95 3.46E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS01665 2688c500e91f91deea49339636bb8063 488 SMART SM00345 28 86 1.8E-4 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CDC59_RS01665 2688c500e91f91deea49339636bb8063 488 Gene3D G3DSA:1.10.10.10 15 88 1.1E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS01665 2688c500e91f91deea49339636bb8063 488 Gene3D G3DSA:3.40.640.10 138 385 1.1E-44 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDC59_RS01665 2688c500e91f91deea49339636bb8063 488 Pfam PF00155 Aminotransferase class I and II 152 443 6.9E-22 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CDC59_RS20290 5997e7317eb98218bd55196ec7ca958d 302 SUPERFAMILY SSF46785 5 85 2.18E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS20290 5997e7317eb98218bd55196ec7ca958d 302 Gene3D G3DSA:1.10.10.10 1 89 8.4E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS20290 5997e7317eb98218bd55196ec7ca958d 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 68 1.7E-15 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS20290 5997e7317eb98218bd55196ec7ca958d 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 4.8E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS20290 5997e7317eb98218bd55196ec7ca958d 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 4.8E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS20290 5997e7317eb98218bd55196ec7ca958d 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 4.8E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS20290 5997e7317eb98218bd55196ec7ca958d 302 SUPERFAMILY SSF53850 90 295 1.1E-40 T 29-03-2018 CDC59_RS20290 5997e7317eb98218bd55196ec7ca958d 302 Gene3D G3DSA:3.40.190.10 195 302 1.5E-7 T 29-03-2018 CDC59_RS20290 5997e7317eb98218bd55196ec7ca958d 302 Gene3D G3DSA:3.40.190.10 90 194 4.0E-21 T 29-03-2018 CDC59_RS20290 5997e7317eb98218bd55196ec7ca958d 302 Pfam PF03466 LysR substrate binding domain 94 295 1.1E-23 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS01285 8de25bac9d6b94213015c5dbbd98e627 266 SMART SM00028 66 99 420.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CDC59_RS01285 8de25bac9d6b94213015c5dbbd98e627 266 SMART SM00028 32 65 250.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CDC59_RS01285 8de25bac9d6b94213015c5dbbd98e627 266 SMART SM00028 100 133 1.6 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CDC59_RS01285 8de25bac9d6b94213015c5dbbd98e627 266 SMART SM00028 134 167 16.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CDC59_RS01285 8de25bac9d6b94213015c5dbbd98e627 266 Gene3D G3DSA:1.25.40.10 10 55 4.1E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS01285 8de25bac9d6b94213015c5dbbd98e627 266 Pfam PF13431 Tetratricopeptide repeat 55 86 2.5E-6 T 29-03-2018 CDC59_RS01285 8de25bac9d6b94213015c5dbbd98e627 266 Gene3D G3DSA:1.25.40.10 119 176 6.1E-16 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS01285 8de25bac9d6b94213015c5dbbd98e627 266 SUPERFAMILY SSF48452 54 181 1.26E-24 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS01285 8de25bac9d6b94213015c5dbbd98e627 266 Pfam PF13432 Tetratricopeptide repeat 107 162 1.4E-7 T 29-03-2018 CDC59_RS01285 8de25bac9d6b94213015c5dbbd98e627 266 Gene3D G3DSA:1.25.40.10 66 118 7.9E-15 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS01285 8de25bac9d6b94213015c5dbbd98e627 266 Gene3D G3DSA:1.10.287.1110 56 65 0.0042 T 29-03-2018 CDC59_RS01285 8de25bac9d6b94213015c5dbbd98e627 266 Gene3D G3DSA:1.25.40.10 177 241 0.044 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS11970 b292ea2d5321455fa793dfa348d3154a 314 SUPERFAMILY SSF53850 91 300 2.9E-40 T 29-03-2018 CDC59_RS11970 b292ea2d5321455fa793dfa348d3154a 314 Gene3D G3DSA:3.40.190.10 182 273 3.8E-13 T 29-03-2018 CDC59_RS11970 b292ea2d5321455fa793dfa348d3154a 314 Pfam PF03466 LysR substrate binding domain 97 301 2.4E-21 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS11970 b292ea2d5321455fa793dfa348d3154a 314 SUPERFAMILY SSF46785 6 85 3.92E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS11970 b292ea2d5321455fa793dfa348d3154a 314 Gene3D G3DSA:1.10.10.10 1 91 6.4E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS11970 b292ea2d5321455fa793dfa348d3154a 314 Gene3D G3DSA:3.40.190.10 95 181 1.5E-14 T 29-03-2018 CDC59_RS11970 b292ea2d5321455fa793dfa348d3154a 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 67 1.8E-13 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS15345 9c1bb6ce57ce89b0a97c12e51f52d9d1 324 SUPERFAMILY SSF111369 142 258 2.62E-6 T 29-03-2018 CDC59_RS15345 9c1bb6ce57ce89b0a97c12e51f52d9d1 324 Pfam PF13437 HlyD family secretion protein 206 316 6.5E-17 T 29-03-2018 CDC59_RS15345 9c1bb6ce57ce89b0a97c12e51f52d9d1 324 Gene3D G3DSA:2.40.50.100 41 234 2.0E-11 T 29-03-2018 CDC59_RS15345 9c1bb6ce57ce89b0a97c12e51f52d9d1 324 SUPERFAMILY SSF111369 41 121 4.45E-6 T 29-03-2018 CDC59_RS15345 9c1bb6ce57ce89b0a97c12e51f52d9d1 324 Pfam PF13533 Biotin-lipoyl like 43 88 3.4E-8 T 29-03-2018 CDC59_RS23125 10925559790bcc53977c21387a9813d7 186 PIRSF PIRSF003159 1 181 7.5E-84 T 29-03-2018 IPR007944 Flagellar transcriptional activator FlhC GO:0003677|GO:0045893|GO:1902208 CDC59_RS23125 10925559790bcc53977c21387a9813d7 186 Pfam PF05280 Flagellar transcriptional activator (FlhC) 1 172 1.9E-82 T 29-03-2018 IPR007944 Flagellar transcriptional activator FlhC GO:0003677|GO:0045893|GO:1902208 CDC59_RS23125 10925559790bcc53977c21387a9813d7 186 ProDom PD016592 ACTIVATOR TRANSCRIPTIONAL FLAGELLUM FLAGELLAR TRANSCRIPTION FLHC RNA DNA-BINDING REGULATION DNA-DIRECTED 1 185 2.0E-96 T 29-03-2018 IPR007944 Flagellar transcriptional activator FlhC GO:0003677|GO:0045893|GO:1902208 CDC59_RS23125 10925559790bcc53977c21387a9813d7 186 Hamap MF_01891 Flagellar transcriptional regulator FlhC [flhC]. 1 186 42.899 T 29-03-2018 IPR007944 Flagellar transcriptional activator FlhC GO:0003677|GO:0045893|GO:1902208 CDC59_RS23125 10925559790bcc53977c21387a9813d7 186 SUPERFAMILY SSF160930 5 160 1.24E-60 T 29-03-2018 CDC59_RS08115 c7bd92273dceaca889f681412946360f 275 Gene3D G3DSA:3.10.350.10 60 111 8.4E-14 T 29-03-2018 CDC59_RS08115 c7bd92273dceaca889f681412946360f 275 SUPERFAMILY SSF51261 63 272 2.72E-45 T 29-03-2018 IPR011055 Duplicated hybrid motif CDC59_RS08115 c7bd92273dceaca889f681412946360f 275 Gene3D G3DSA:2.70.70.10 112 275 5.9E-36 T 29-03-2018 CDC59_RS08115 c7bd92273dceaca889f681412946360f 275 SMART SM00257 63 107 1.1E-9 T 29-03-2018 IPR018392 LysM domain CDC59_RS08115 c7bd92273dceaca889f681412946360f 275 Pfam PF01476 LysM domain 64 106 3.7E-11 T 29-03-2018 IPR018392 LysM domain CDC59_RS08115 c7bd92273dceaca889f681412946360f 275 Pfam PF01551 Peptidase family M23 176 268 1.6E-28 T 29-03-2018 IPR016047 Peptidase M23 CDC59_RS06055 44e4f797b1db40dec8b96453643c270a 791 Pfam PF00580 UvrD/REP helicase N-terminal domain 8 274 2.5E-74 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CDC59_RS06055 44e4f797b1db40dec8b96453643c270a 791 Gene3D G3DSA:3.40.50.300 405 709 4.2E-47 T 29-03-2018 CDC59_RS06055 44e4f797b1db40dec8b96453643c270a 791 Gene3D G3DSA:3.40.50.300 286 387 1.0E-24 T 29-03-2018 CDC59_RS06055 44e4f797b1db40dec8b96453643c270a 791 SUPERFAMILY SSF52540 556 674 2.26E-170 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS06055 44e4f797b1db40dec8b96453643c270a 791 SUPERFAMILY SSF52540 1 514 2.26E-170 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS06055 44e4f797b1db40dec8b96453643c270a 791 Pfam PF13361 UvrD-like helicase C-terminal domain 280 649 2.8E-68 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CDC59_RS06055 44e4f797b1db40dec8b96453643c270a 791 Gene3D G3DSA:3.40.50.300 142 285 1.4E-29 T 29-03-2018 CDC59_RS06055 44e4f797b1db40dec8b96453643c270a 791 Gene3D G3DSA:3.40.50.300 1 141 1.2E-28 T 29-03-2018 CDC59_RS09410 9277cb4005cca77b12887bdf537a020f 308 Gene3D G3DSA:3.40.50.10740 1 146 6.8E-34 T 29-03-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal domain CDC59_RS09410 9277cb4005cca77b12887bdf537a020f 308 SUPERFAMILY SSF141986 137 294 8.24E-47 T 29-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain CDC59_RS09410 9277cb4005cca77b12887bdf537a020f 308 Pfam PF02016 LD-carboxypeptidase 4 289 9.7E-67 T 29-03-2018 IPR003507 Peptidase family S66 CDC59_RS09410 9277cb4005cca77b12887bdf537a020f 308 SUPERFAMILY SSF52317 3 158 1.1E-32 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CDC59_RS09410 9277cb4005cca77b12887bdf537a020f 308 Gene3D G3DSA:3.50.30.60 147 303 6.6E-47 T 29-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain CDC59_RS09410 9277cb4005cca77b12887bdf537a020f 308 PIRSF PIRSF028757 1 302 1.3E-71 T 29-03-2018 IPR003507 Peptidase family S66 CDC59_RS15150 61603e3f2b999019ea512db5caa822e0 211 PIRSF PIRSF006324 1 210 3.0E-53 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CDC59_RS15150 61603e3f2b999019ea512db5caa822e0 211 Pfam PF01810 LysE type translocator 15 202 2.1E-25 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CDC59_RS22765 4fa57c425135340b4b7df82607f57ac6 234 TIGRFAM TIGR01198 pgl: 6-phosphogluconolactonase 10 226 1.7E-55 T 29-03-2018 IPR005900 6-phosphogluconolactonase, DevB-type GO:0005975|GO:0006098|GO:0017057 KEGG: 00030+3.1.1.31 CDC59_RS22765 4fa57c425135340b4b7df82607f57ac6 234 Gene3D G3DSA:3.40.50.1360 1 234 3.3E-49 T 29-03-2018 CDC59_RS22765 4fa57c425135340b4b7df82607f57ac6 234 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 10 224 1.8E-50 T 29-03-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 CDC59_RS22765 4fa57c425135340b4b7df82607f57ac6 234 SUPERFAMILY SSF100950 4 227 5.92E-51 T 29-03-2018 CDC59_RS02355 1efcea213eda9565a48e67a85a0c23a4 133 Pfam PF00411 Ribosomal protein S11 23 132 3.9E-51 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CDC59_RS02355 1efcea213eda9565a48e67a85a0c23a4 133 SUPERFAMILY SSF53137 18 133 2.35E-47 T 29-03-2018 CDC59_RS02355 1efcea213eda9565a48e67a85a0c23a4 133 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 133 32.922 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CDC59_RS02355 1efcea213eda9565a48e67a85a0c23a4 133 PIRSF PIRSF002131 1 133 3.6E-52 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CDC59_RS02355 1efcea213eda9565a48e67a85a0c23a4 133 Gene3D G3DSA:3.30.420.80 9 133 5.5E-46 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CDC59_RS02355 1efcea213eda9565a48e67a85a0c23a4 133 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 14 130 2.0E-55 T 29-03-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS02355 1efcea213eda9565a48e67a85a0c23a4 133 ProSitePatterns PS00054 Ribosomal protein S11 signature. 101 123 - T 29-03-2018 IPR018102 Ribosomal S11, conserved site CDC59_RS09570 ff11b3e7dbbf24c462f2dc8780e24e02 455 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 95 118 - T 29-03-2018 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0016705|GO:0051537|GO:0055114 CDC59_RS09570 ff11b3e7dbbf24c462f2dc8780e24e02 455 Pfam PF00355 Rieske [2Fe-2S] domain 52 136 5.8E-22 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CDC59_RS09570 ff11b3e7dbbf24c462f2dc8780e24e02 455 TIGRFAM TIGR03229 benzo_1_2_benA: benzoate 1,2-dioxygenase, large subunit 15 447 2.3E-273 T 29-03-2018 IPR017639 Benzoate 1,2-dioxygenase, large subunit CDC59_RS09570 ff11b3e7dbbf24c462f2dc8780e24e02 455 SUPERFAMILY SSF55961 171 450 1.96E-69 T 29-03-2018 CDC59_RS09570 ff11b3e7dbbf24c462f2dc8780e24e02 455 Gene3D G3DSA:2.102.10.10 31 161 1.2E-21 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CDC59_RS09570 ff11b3e7dbbf24c462f2dc8780e24e02 455 Gene3D G3DSA:3.90.380.10 162 453 3.9E-70 T 29-03-2018 CDC59_RS09570 ff11b3e7dbbf24c462f2dc8780e24e02 455 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 109 129 7.2E-47 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CDC59_RS09570 ff11b3e7dbbf24c462f2dc8780e24e02 455 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 67 82 7.2E-47 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CDC59_RS09570 ff11b3e7dbbf24c462f2dc8780e24e02 455 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 155 181 7.2E-47 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CDC59_RS09570 ff11b3e7dbbf24c462f2dc8780e24e02 455 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 37 62 7.2E-47 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CDC59_RS09570 ff11b3e7dbbf24c462f2dc8780e24e02 455 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 88 108 7.2E-47 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CDC59_RS09570 ff11b3e7dbbf24c462f2dc8780e24e02 455 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 196 218 7.2E-47 T 29-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CDC59_RS09570 ff11b3e7dbbf24c462f2dc8780e24e02 455 SUPERFAMILY SSF50022 15 171 1.22E-46 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CDC59_RS09570 ff11b3e7dbbf24c462f2dc8780e24e02 455 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 202 393 2.8E-18 T 29-03-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 CDC59_RS04860 3a0a251dc11ba7679709a0ff7919f58d 294 Pfam PF03301 Tryptophan 2,3-dioxygenase 27 163 4.7E-41 T 29-03-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 CDC59_RS04860 3a0a251dc11ba7679709a0ff7919f58d 294 Pfam PF03301 Tryptophan 2,3-dioxygenase 205 292 2.8E-26 T 29-03-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 CDC59_RS04860 3a0a251dc11ba7679709a0ff7919f58d 294 Hamap MF_01972 Tryptophan 2,3-dioxygenase [kynA]. 31 294 41.56 T 29-03-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 CDC59_RS04860 3a0a251dc11ba7679709a0ff7919f58d 294 SUPERFAMILY SSF140959 37 293 2.35E-105 T 29-03-2018 CDC59_RS04860 3a0a251dc11ba7679709a0ff7919f58d 294 TIGRFAM TIGR03036 trp_2_3_diox: tryptophan 2,3-dioxygenase 31 294 1.4E-138 T 29-03-2018 IPR017485 Tryptophan 2,3-dioxygenase, bacterial GO:0004833|GO:0019441 KEGG: 00380+1.13.11.11 CDC59_RS11045 6a20fb648385ba320b94edccc8fdf34f 313 SUPERFAMILY SSF48431 38 139 5.49E-8 T 29-03-2018 IPR011030 Vitellinogen, superhelical GO:0005319|GO:0006869 Reactome: R-HSA-8866423|Reactome: R-HSA-8963888 CDC59_RS11045 6a20fb648385ba320b94edccc8fdf34f 313 SUPERFAMILY SSF48431 202 272 5.49E-8 T 29-03-2018 IPR011030 Vitellinogen, superhelical GO:0005319|GO:0006869 Reactome: R-HSA-8866423|Reactome: R-HSA-8963888 CDC59_RS11045 6a20fb648385ba320b94edccc8fdf34f 313 Gene3D G3DSA:1.25.10.10 37 303 1.3E-8 T 29-03-2018 IPR011989 Armadillo-like helical CDC59_RS00725 b4946fecfc11d8de5497fea92fe4b0ea 328 Pfam PF02653 Branched-chain amino acid transport system / permease component 32 276 9.4E-33 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CDC59_RS00725 b4946fecfc11d8de5497fea92fe4b0ea 328 Gene3D G3DSA:1.10.3470.10 1 314 4.2E-41 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CDC59_RS03520 8c817a28cc54ba2cb67370823dbe4ecb 143 Pfam PF00545 ribonuclease 57 140 8.8E-30 T 29-03-2018 IPR000026 Guanine-specific ribonuclease N1/T1/U2 GO:0003723|GO:0004521 CDC59_RS03520 8c817a28cc54ba2cb67370823dbe4ecb 143 SUPERFAMILY SSF53933 47 142 1.47E-35 T 29-03-2018 IPR016191 Ribonuclease/ribotoxin GO:0003723|GO:0004540 CDC59_RS03520 8c817a28cc54ba2cb67370823dbe4ecb 143 Gene3D G3DSA:3.10.450.30 47 143 7.1E-33 T 29-03-2018 CDC59_RS15395 72b77a3d3d40a969d489e2c348906fce 314 Pfam PF01435 Peptidase family M48 86 264 3.8E-29 T 29-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CDC59_RS15395 72b77a3d3d40a969d489e2c348906fce 314 Gene3D G3DSA:3.30.2010.10 50 170 2.5E-18 T 29-03-2018 CDC59_RS18290 3a81c92ac644880c745ef331258fba38 294 Pfam PF01136 Peptidase family U32 109 246 7.6E-12 T 29-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 CDC59_RS21590 f95f20a79f4496bdf31ec92a5a44c004 255 Pfam PF14451 Mut7-C ubiquitin 1 80 7.9E-26 T 29-03-2018 IPR027798 Ubiquitin Mut7-C domain CDC59_RS21590 f95f20a79f4496bdf31ec92a5a44c004 255 Pfam PF01927 Mut7-C RNAse domain 86 228 6.0E-47 T 29-03-2018 IPR002782 Mut7-C RNAse domain CDC59_RS15020 561afbf158e9d01f6290334cb34fa2ba 313 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 107 278 1.6E-42 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CDC59_RS15020 561afbf158e9d01f6290334cb34fa2ba 313 Gene3D G3DSA:3.40.50.720 3 125 1.2E-14 T 29-03-2018 CDC59_RS15020 561afbf158e9d01f6290334cb34fa2ba 313 Gene3D G3DSA:3.40.50.720 126 279 1.6E-36 T 29-03-2018 CDC59_RS15020 561afbf158e9d01f6290334cb34fa2ba 313 SUPERFAMILY SSF51735 100 278 2.59E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS02600 74b5573d8d9fd054723a48fdc4b26f63 247 SUPERFAMILY SSF51366 1 240 6.12E-77 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CDC59_RS02600 74b5573d8d9fd054723a48fdc4b26f63 247 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 2 240 36.513 T 29-03-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 CDC59_RS02600 74b5573d8d9fd054723a48fdc4b26f63 247 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 3 236 3.1E-78 T 29-03-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 CDC59_RS02600 74b5573d8d9fd054723a48fdc4b26f63 247 Pfam PF00977 Histidine biosynthesis protein 3 232 5.2E-81 T 29-03-2018 IPR006062 Histidine biosynthesis GO:0000105 CDC59_RS02600 74b5573d8d9fd054723a48fdc4b26f63 247 Gene3D G3DSA:3.20.20.70 2 245 4.1E-61 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS08450 b7a302a0f39ec0c8fa3ce7948eaeb707 282 Gene3D G3DSA:1.10.3720.10 70 280 5.6E-35 T 29-03-2018 CDC59_RS08450 b7a302a0f39ec0c8fa3ce7948eaeb707 282 SUPERFAMILY SSF161098 4 278 4.45E-61 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS08450 b7a302a0f39ec0c8fa3ce7948eaeb707 282 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 277 5.6E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS10780 8320308c2e77f2714bac640028f34043 151 SMART SM00116 79 126 0.088 T 29-03-2018 IPR000644 CBS domain CDC59_RS10780 8320308c2e77f2714bac640028f34043 151 SMART SM00116 13 60 2.2E-7 T 29-03-2018 IPR000644 CBS domain CDC59_RS10780 8320308c2e77f2714bac640028f34043 151 Pfam PF00571 CBS domain 73 125 2.0E-8 T 29-03-2018 IPR000644 CBS domain CDC59_RS10780 8320308c2e77f2714bac640028f34043 151 Pfam PF00571 CBS domain 15 60 5.1E-8 T 29-03-2018 IPR000644 CBS domain CDC59_RS10780 8320308c2e77f2714bac640028f34043 151 SUPERFAMILY SSF54631 1 130 2.65E-28 T 29-03-2018 CDC59_RS10780 8320308c2e77f2714bac640028f34043 151 Gene3D G3DSA:3.10.580.10 1 149 1.7E-25 T 29-03-2018 CDC59_RS02665 afe0ae01af962e25cbab1a8581e41e49 380 SUPERFAMILY SSF53850 59 358 1.61E-47 T 29-03-2018 CDC59_RS02665 afe0ae01af962e25cbab1a8581e41e49 380 Gene3D G3DSA:3.40.190.10 8 192 7.7E-21 T 29-03-2018 CDC59_RS02665 afe0ae01af962e25cbab1a8581e41e49 380 Gene3D G3DSA:3.40.190.10 206 346 1.8E-12 T 29-03-2018 CDC59_RS02665 afe0ae01af962e25cbab1a8581e41e49 380 Pfam PF13531 Bacterial extracellular solute-binding protein 63 320 2.5E-14 T 29-03-2018 CDC59_RS04740 f917ced8c0721a9f393fc9b334269f52 333 Gene3D G3DSA:3.30.1150.10 238 332 7.2E-17 T 29-03-2018 CDC59_RS04740 f917ced8c0721a9f393fc9b334269f52 333 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 272 331 4.5E-9 T 29-03-2018 IPR006260 TonB, C-terminal GO:0006810 CDC59_RS04740 f917ced8c0721a9f393fc9b334269f52 333 Pfam PF13103 TonB C terminal 247 329 2.7E-22 T 29-03-2018 IPR006260 TonB, C-terminal GO:0006810 CDC59_RS04740 f917ced8c0721a9f393fc9b334269f52 333 TIGRFAM TIGR02794 tolA_full: protein TolA 19 331 7.4E-46 T 29-03-2018 IPR014161 Tol-Pal system, TolA GO:0005215|GO:0006810|GO:0016020 CDC59_RS04740 f917ced8c0721a9f393fc9b334269f52 333 SUPERFAMILY SSF74653 242 332 3.66E-18 T 29-03-2018 CDC59_RS00815 5ccdde8dc2e21c8299189c02b4f78a56 192 Pfam PF03899 ATP synthase I chain 78 179 7.4E-18 T 29-03-2018 IPR005598 ATP synthase protein I CDC59_RS02525 77d60874eb4dcb6676bd36f85d26c77b 255 Pfam PF02405 Permease MlaE 41 252 1.5E-75 T 29-03-2018 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 CDC59_RS02525 77d60874eb4dcb6676bd36f85d26c77b 255 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 34 254 6.2E-80 T 29-03-2018 IPR003453 ABC transport permease subunit MlaE, Proteobacteria CDC59_RS01240 2559b05f4535ede06f1387bbd0b4b95c 380 Gene3D G3DSA:3.40.50.150 45 380 9.2E-28 T 29-03-2018 CDC59_RS01240 2559b05f4535ede06f1387bbd0b4b95c 380 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 269 275 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CDC59_RS01240 2559b05f4535ede06f1387bbd0b4b95c 380 SUPERFAMILY SSF53335 173 319 3.96E-29 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS01240 2559b05f4535ede06f1387bbd0b4b95c 380 Pfam PF05175 Methyltransferase small domain 198 318 1.2E-12 T 29-03-2018 IPR007848 Methyltransferase small domain GO:0008168 CDC59_RS10725 348b7d8b3e02e186f22eb2787dcd8e0b 122 Pfam PF01042 Endoribonuclease L-PSP 9 119 7.4E-27 T 29-03-2018 IPR006175 YjgF/YER057c/UK114 family CDC59_RS10725 348b7d8b3e02e186f22eb2787dcd8e0b 122 Gene3D G3DSA:3.30.1330.40 4 122 1.3E-24 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CDC59_RS10725 348b7d8b3e02e186f22eb2787dcd8e0b 122 SUPERFAMILY SSF55298 6 120 4.08E-27 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CDC59_RS10725 348b7d8b3e02e186f22eb2787dcd8e0b 122 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 96 114 - T 29-03-2018 IPR019897 RidA, conserved site CDC59_RS07030 f35fb9ebe8e7cc15c0aaf43befb2db16 291 SUPERFAMILY SSF53335 47 267 4.85E-46 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS07030 f35fb9ebe8e7cc15c0aaf43befb2db16 291 Gene3D G3DSA:3.40.50.150 38 287 1.6E-20 T 29-03-2018 CDC59_RS23430 6c6c6f245a7b5d1769b1c28ca1f7a5be 240 TIGRFAM TIGR03187 DGQHR: DGQHR domain 11 222 5.0E-28 T 29-03-2018 IPR017601 DGQHR-containing domain CDC59_RS23430 6c6c6f245a7b5d1769b1c28ca1f7a5be 240 Pfam PF14072 DNA-sulfur modification-associated 10 161 1.1E-22 T 29-03-2018 IPR017642 DNA sulphur modification protein DndB CDC59_RS13400 ea330569b88f146b01799f1529550afe 568 Gene3D G3DSA:1.25.40.10 210 552 6.3E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS13400 ea330569b88f146b01799f1529550afe 568 Gene3D G3DSA:3.30.2010.10 105 209 9.3E-17 T 29-03-2018 CDC59_RS13400 ea330569b88f146b01799f1529550afe 568 Pfam PF01435 Peptidase family M48 147 323 1.9E-28 T 29-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CDC59_RS13400 ea330569b88f146b01799f1529550afe 568 SUPERFAMILY SSF48452 378 503 2.28E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS12370 89c634fde93fa6e166e7eda945dfd6fb 106 Gene3D G3DSA:1.20.5.340 1 83 6.0E-6 T 29-03-2018 CDC59_RS19940 e4529b1fbdcd908378bc071cd2034e46 554 Hamap MF_00212 Probable malate:quinone oxidoreductase [mqo]. 25 515 53.662 T 29-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 CDC59_RS19940 e4529b1fbdcd908378bc071cd2034e46 554 Gene3D G3DSA:3.50.50.60 21 491 1.8E-15 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS19940 e4529b1fbdcd908378bc071cd2034e46 554 SUPERFAMILY SSF51905 22 88 1.58E-22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS19940 e4529b1fbdcd908378bc071cd2034e46 554 SUPERFAMILY SSF51905 122 355 1.58E-22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS19940 e4529b1fbdcd908378bc071cd2034e46 554 Pfam PF06039 Malate:quinone oxidoreductase (Mqo) 28 515 1.9E-233 T 29-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 CDC59_RS19940 e4529b1fbdcd908378bc071cd2034e46 554 TIGRFAM TIGR01320 mal_quin_oxido: malate dehydrogenase (acceptor) 29 513 9.1E-209 T 29-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 CDC59_RS17005 af7397f61b129f36ff563ba461960e78 153 PIRSF PIRSF002889 1 153 2.8E-37 T 29-03-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 CDC59_RS17005 af7397f61b129f36ff563ba461960e78 153 TIGRFAM TIGR01396 FlgB: flagellar basal-body rod protein FlgB 6 151 4.9E-31 T 29-03-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 CDC59_RS17005 af7397f61b129f36ff563ba461960e78 153 Pfam PF00460 Flagella basal body rod protein 11 39 1.7E-4 T 29-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CDC59_RS12310 fedde5921951a582ea2fb0f058da15bc 495 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 494 214.208 T 29-03-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 CDC59_RS12310 fedde5921951a582ea2fb0f058da15bc 495 Gene3D G3DSA:3.40.50.300 11 248 6.5E-55 T 29-03-2018 CDC59_RS12310 fedde5921951a582ea2fb0f058da15bc 495 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 14 239 4.0E-21 T 29-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CDC59_RS12310 fedde5921951a582ea2fb0f058da15bc 495 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 260 443 7.7E-58 T 29-03-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 CDC59_RS12310 fedde5921951a582ea2fb0f058da15bc 495 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 14 485 1.0E-142 T 29-03-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 CDC59_RS12310 fedde5921951a582ea2fb0f058da15bc 495 Gene3D G3DSA:3.40.50.880 249 484 5.7E-26 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CDC59_RS12310 fedde5921951a582ea2fb0f058da15bc 495 SUPERFAMILY SSF52540 13 246 9.07E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS12310 fedde5921951a582ea2fb0f058da15bc 495 SUPERFAMILY SSF52317 261 453 2.66E-40 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CDC59_RS05055 2506a39ffd3371a745b0b1a7b62defbc 368 PIRSF PIRSF013171 2 368 2.5E-168 T 29-03-2018 IPR009486 Purine nucleoside permease GO:0055085 CDC59_RS05055 2506a39ffd3371a745b0b1a7b62defbc 368 Gene3D G3DSA:3.40.50.1580 52 325 1.8E-18 T 29-03-2018 CDC59_RS05055 2506a39ffd3371a745b0b1a7b62defbc 368 Pfam PF06516 Purine nucleoside permease (NUP) 56 366 3.7E-127 T 29-03-2018 IPR009486 Purine nucleoside permease GO:0055085 CDC59_RS09485 6c921c60c34a3b41ba09138c0db0d7e5 301 SMART SM00382 34 204 8.0E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS09485 6c921c60c34a3b41ba09138c0db0d7e5 301 SUPERFAMILY SSF52540 23 281 1.34E-32 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS09485 6c921c60c34a3b41ba09138c0db0d7e5 301 Pfam PF07728 AAA domain (dynein-related subfamily) 38 195 1.0E-10 T 29-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 CDC59_RS09485 6c921c60c34a3b41ba09138c0db0d7e5 301 Gene3D G3DSA:3.40.50.300 6 238 4.7E-27 T 29-03-2018 CDC59_RS22310 feb03c142e588ff9d92e29c80ef794ac 527 Pfam PF01564 Spermine/spermidine synthase domain 288 462 3.0E-31 T 29-03-2018 CDC59_RS22310 feb03c142e588ff9d92e29c80ef794ac 527 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 201 505 22.828 T 29-03-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 CDC59_RS22310 feb03c142e588ff9d92e29c80ef794ac 527 Gene3D G3DSA:3.40.50.150 285 503 9.9E-40 T 29-03-2018 CDC59_RS22310 feb03c142e588ff9d92e29c80ef794ac 527 SUPERFAMILY SSF53335 232 498 2.04E-63 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS03900 3734934074cebe6f352087156f9e3aa2 178 Pfam PF14341 PilX N-terminal 9 59 2.6E-8 T 29-03-2018 IPR025746 Type 4 fimbrial biogenesis protein PilX, N-terminal domain CDC59_RS21405 ea45c93badaea660cd6f0fc043470f77 236 Pfam PF12840 Helix-turn-helix domain 17 70 1.1E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS21405 ea45c93badaea660cd6f0fc043470f77 236 Gene3D G3DSA:1.10.10.10 3 92 4.3E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS21405 ea45c93badaea660cd6f0fc043470f77 236 SMART SM00418 16 95 3.6E-12 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CDC59_RS21405 ea45c93badaea660cd6f0fc043470f77 236 SUPERFAMILY SSF46785 13 124 1.53E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS21405 ea45c93badaea660cd6f0fc043470f77 236 Gene3D G3DSA:1.10.10.10 93 207 0.37 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS21505 3c933917faebb80d2b954f9d25804659 463 Gene3D G3DSA:1.20.120.20 37 438 1.7E-6 T 29-03-2018 CDC59_RS21505 3c933917faebb80d2b954f9d25804659 463 Pfam PF15984 Bacterial collagen, middle region 108 303 1.2E-69 T 29-03-2018 IPR031929 Bacterial collagen-like protein, middle domain CDC59_RS14640 256f80399e3660e253d61a0713bf127e 215 Gene3D G3DSA:3.40.50.1820 4 209 1.6E-25 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS14640 256f80399e3660e253d61a0713bf127e 215 SUPERFAMILY SSF53474 3 208 6.24E-38 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS14640 256f80399e3660e253d61a0713bf127e 215 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 48 127 1.6E-7 T 29-03-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 CDC59_RS18625 d9d89e57710c2b5d2393406327360769 147 Pfam PF11448 Protein of unknown function (DUF3005) 27 123 8.2E-37 T 29-03-2018 IPR021551 Protein of unknown function DUF3005 CDC59_RS12010 6e9f5d97b20e2d563c48e36826110c85 95 Gene3D G3DSA:3.40.50.280 5 80 5.2E-4 T 29-03-2018 CDC59_RS08715 425d5da2a4bc0f36aa76517c8f6dbbe0 154 PIRSF PIRSF000239 1 154 6.7E-28 T 29-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CDC59_RS08715 425d5da2a4bc0f36aa76517c8f6dbbe0 154 Gene3D G3DSA:3.40.30.10 1 154 6.2E-34 T 29-03-2018 CDC59_RS08715 425d5da2a4bc0f36aa76517c8f6dbbe0 154 SUPERFAMILY SSF52833 3 154 5.44E-49 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS08715 425d5da2a4bc0f36aa76517c8f6dbbe0 154 Pfam PF00578 AhpC/TSA family 7 133 7.2E-33 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CDC59_RS05405 1c061b0c7b66f9003ecef42ae6ea0085 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 12 27 3.8E-5 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CDC59_RS05405 1c061b0c7b66f9003ecef42ae6ea0085 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 3.8E-5 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CDC59_RS05405 1c061b0c7b66f9003ecef42ae6ea0085 111 Gene3D G3DSA:1.10.10.10 1 98 1.4E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS05405 1c061b0c7b66f9003ecef42ae6ea0085 111 Pfam PF12840 Helix-turn-helix domain 10 69 2.6E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS05405 1c061b0c7b66f9003ecef42ae6ea0085 111 SUPERFAMILY SSF46785 3 102 3.14E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS05405 1c061b0c7b66f9003ecef42ae6ea0085 111 SMART SM00418 10 89 3.4E-16 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CDC59_RS06955 294a85db845a076c68239265f8103eef 561 Pfam PF02652 L-lactate permease 15 546 6.7E-151 T 29-03-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 CDC59_RS06955 294a85db845a076c68239265f8103eef 561 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 4 548 1.7E-151 T 29-03-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 CDC59_RS02680 3c69cbfc01f19436f9cd91db742f6220 248 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 2 247 2.6E-58 T 29-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CDC59_RS02680 3c69cbfc01f19436f9cd91db742f6220 248 Gene3D G3DSA:3.40.1390.30 109 219 3.7E-32 T 29-03-2018 CDC59_RS02680 3c69cbfc01f19436f9cd91db742f6220 248 Gene3D G3DSA:3.40.1390.30 1 108 2.1E-23 T 29-03-2018 CDC59_RS02680 3c69cbfc01f19436f9cd91db742f6220 248 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 9 236 4.9E-55 T 29-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CDC59_RS02680 3c69cbfc01f19436f9cd91db742f6220 248 SUPERFAMILY SSF102705 1 247 1.57E-78 T 29-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CDC59_RS15055 713c28534ac1605978712ccf901f78f9 311 Gene3D G3DSA:3.40.50.1820 14 311 1.2E-43 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS15055 713c28534ac1605978712ccf901f78f9 311 SUPERFAMILY SSF53474 20 310 5.9E-68 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS15055 713c28534ac1605978712ccf901f78f9 311 Pfam PF00561 alpha/beta hydrolase fold 46 155 2.0E-16 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS09525 266e561907157491d091f8d0bcb0c160 167 Gene3D G3DSA:3.30.1460.10 28 162 7.6E-6 T 29-03-2018 CDC59_RS04910 f9e09cd38f125e0449c248a66030ce76 742 Gene3D G3DSA:3.20.20.300 76 474 2.3E-86 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CDC59_RS04910 f9e09cd38f125e0449c248a66030ce76 742 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 362 379 - T 29-03-2018 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 CDC59_RS04910 f9e09cd38f125e0449c248a66030ce76 742 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 488 724 7.1E-9 T 29-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CDC59_RS04910 f9e09cd38f125e0449c248a66030ce76 742 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 95 449 3.0E-77 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CDC59_RS04910 f9e09cd38f125e0449c248a66030ce76 742 SUPERFAMILY SSF52279 606 742 4.84E-10 T 29-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CDC59_RS04910 f9e09cd38f125e0449c248a66030ce76 742 SUPERFAMILY SSF52279 488 562 4.84E-10 T 29-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CDC59_RS04910 f9e09cd38f125e0449c248a66030ce76 742 SUPERFAMILY SSF51445 82 487 1.9E-82 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CDC59_RS04910 f9e09cd38f125e0449c248a66030ce76 742 Gene3D G3DSA:3.40.50.1700 475 742 3.8E-18 T 29-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CDC59_RS14415 2da02395bba23eb5175b07fcc1ae3d2e 200 Pfam PF02630 SCO1/SenC 21 178 1.3E-38 T 29-03-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS14415 2da02395bba23eb5175b07fcc1ae3d2e 200 SUPERFAMILY SSF52833 41 199 6.1E-51 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS14415 2da02395bba23eb5175b07fcc1ae3d2e 200 Gene3D G3DSA:3.40.30.10 41 199 1.1E-33 T 29-03-2018 CDC59_RS07365 340833a5478b8d357c9304189348ea8e 122 Pfam PF16137 Domain of unknown function (DUF4845) 36 117 2.1E-18 T 29-03-2018 IPR032314 Protein of unknown function DUF4845 CDC59_RS08515 783370e80854b1b85b8f84e904b07de2 314 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 220 295 4.5E-12 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS08515 783370e80854b1b85b8f84e904b07de2 314 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 135 207 3.7E-11 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS08515 783370e80854b1b85b8f84e904b07de2 314 PRINTS PR00605 Class IC cytochrome C signature 273 295 7.4E-5 T 29-03-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 CDC59_RS08515 783370e80854b1b85b8f84e904b07de2 314 PRINTS PR00605 Class IC cytochrome C signature 143 154 7.4E-5 T 29-03-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 CDC59_RS08515 783370e80854b1b85b8f84e904b07de2 314 PIRSF PIRSF000006 5 302 4.9E-108 T 29-03-2018 IPR004678 Cytochrome c oxidase cbb3-type, subunit III CDC59_RS08515 783370e80854b1b85b8f84e904b07de2 314 SUPERFAMILY SSF46626 219 303 1.67E-23 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS08515 783370e80854b1b85b8f84e904b07de2 314 TIGRFAM TIGR00782 ccoP: cytochrome c oxidase, cbb3-type, subunit III 44 300 1.5E-84 T 29-03-2018 IPR004678 Cytochrome c oxidase cbb3-type, subunit III CDC59_RS08515 783370e80854b1b85b8f84e904b07de2 314 Pfam PF14715 N-terminal domain of cytochrome oxidase-cbb3, FixP 44 89 1.4E-23 T 29-03-2018 IPR032858 Cbb3-type cytochrome c oxidase subunit CcoP, N-terminal CDC59_RS08515 783370e80854b1b85b8f84e904b07de2 314 SUPERFAMILY SSF46626 113 213 1.03E-31 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS08515 783370e80854b1b85b8f84e904b07de2 314 SUPERFAMILY SSF46626 62 85 1.03E-31 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS08515 783370e80854b1b85b8f84e904b07de2 314 Gene3D G3DSA:1.10.760.10 214 314 2.1E-19 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS08515 783370e80854b1b85b8f84e904b07de2 314 Gene3D G3DSA:1.10.760.10 97 213 9.9E-22 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS00200 bd90fcf9479743fe49cdeb816ef221a3 286 Gene3D G3DSA:3.40.50.1000 19 269 1.6E-21 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS00200 bd90fcf9479743fe49cdeb816ef221a3 286 Pfam PF13419 Haloacid dehalogenase-like hydrolase 33 215 4.9E-7 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS00200 bd90fcf9479743fe49cdeb816ef221a3 286 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 31 215 3.7E-16 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CDC59_RS00200 bd90fcf9479743fe49cdeb816ef221a3 286 SUPERFAMILY SSF56784 31 219 2.96E-26 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS20670 35e05e28266fedbb3bb478c48d3507d7 128 Pfam PF11162 Protein of unknown function (DUF2946) 12 125 3.3E-12 T 29-03-2018 IPR021333 Protein of unknown function DUF2946 CDC59_RS00715 e9f67c6e9f512037db6cc5ec0861f56c 406 SUPERFAMILY SSF53822 35 404 3.24E-95 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CDC59_RS00715 e9f67c6e9f512037db6cc5ec0861f56c 406 Pfam PF13458 Periplasmic binding protein 34 369 7.0E-92 T 29-03-2018 IPR028081 Leucine-binding protein domain CDC59_RS00715 e9f67c6e9f512037db6cc5ec0861f56c 406 Gene3D G3DSA:3.40.50.2300 19 165 2.6E-21 T 29-03-2018 CDC59_RS00715 e9f67c6e9f512037db6cc5ec0861f56c 406 Gene3D G3DSA:3.40.50.2300 166 315 5.3E-37 T 29-03-2018 CDC59_RS01945 b1b62d237a0ab3b21db3c766e08ae10f 244 Pfam PF16357 Putative PepSY_TM-like 35 237 1.8E-12 T 29-03-2018 IPR032307 Putative PepSY TM-like protein CDC59_RS15405 75d58a73044b87ad1ef6be52e6125196 195 SUPERFAMILY SSF55469 6 192 1.83E-42 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CDC59_RS15405 75d58a73044b87ad1ef6be52e6125196 195 Pfam PF00881 Nitroreductase family 77 160 5.0E-6 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CDC59_RS15405 75d58a73044b87ad1ef6be52e6125196 195 Pfam PF00881 Nitroreductase family 16 61 3.0E-13 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CDC59_RS15405 75d58a73044b87ad1ef6be52e6125196 195 Gene3D G3DSA:3.40.109.10 2 195 1.2E-36 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CDC59_RS19660 1d60dafb6a8093a94bf9b8828509a5a5 367 Pfam PF06996 Type VI secretion, TssG 19 347 1.2E-90 T 29-03-2018 IPR010732 Type VI secretion, TssG-like CDC59_RS19660 1d60dafb6a8093a94bf9b8828509a5a5 367 TIGRFAM TIGR03347 VI_chp_1: type VI secretion protein, VC_A0111 family 19 348 2.1E-103 T 29-03-2018 IPR010732 Type VI secretion, TssG-like CDC59_RS04760 eb2e8194e290952299008e7642901420 224 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 5 208 1.9E-61 T 29-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CDC59_RS04760 eb2e8194e290952299008e7642901420 224 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 3 221 54.972 T 29-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CDC59_RS04760 eb2e8194e290952299008e7642901420 224 SUPERFAMILY SSF52402 2 223 2.09E-65 T 29-03-2018 CDC59_RS04760 eb2e8194e290952299008e7642901420 224 Pfam PF06508 Queuosine biosynthesis protein QueC 4 215 1.7E-78 T 29-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CDC59_RS04760 eb2e8194e290952299008e7642901420 224 PIRSF PIRSF006293 1 224 9.8E-79 T 29-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CDC59_RS04760 eb2e8194e290952299008e7642901420 224 Gene3D G3DSA:3.40.50.620 2 224 6.4E-53 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDC59_RS15625 e7b7a18b875c449dbba6ce26daa159e9 159 SUPERFAMILY SSF54593 12 150 1.11E-34 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CDC59_RS15625 e7b7a18b875c449dbba6ce26daa159e9 159 Gene3D G3DSA:3.10.180.10 9 145 5.4E-26 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CDC59_RS00880 0aae136475efd8a1b2e84d2b2f946bf0 67 Pfam PF12085 Protein of unknown function (DUF3562) 6 63 6.7E-25 T 29-03-2018 IPR021945 Protein of unknown function DUF3562 CDC59_RS08615 f4368cf40468c0edc705a6345591110b 344 TIGRFAM TIGR00742 yjbN: tRNA dihydrouridine synthase A 11 310 3.4E-136 T 29-03-2018 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 CDC59_RS08615 f4368cf40468c0edc705a6345591110b 344 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 94 112 - T 29-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 CDC59_RS08615 f4368cf40468c0edc705a6345591110b 344 PIRSF PIRSF006621 2 333 9.2E-74 T 29-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CDC59_RS08615 f4368cf40468c0edc705a6345591110b 344 Hamap MF_02041 tRNA-dihydrouridine(20/20a) synthase [dusA]. 6 333 50.329 T 29-03-2018 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 CDC59_RS08615 f4368cf40468c0edc705a6345591110b 344 Gene3D G3DSA:3.20.20.70 9 250 3.0E-43 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS08615 f4368cf40468c0edc705a6345591110b 344 SUPERFAMILY SSF51395 12 311 2.36E-75 T 29-03-2018 CDC59_RS08615 f4368cf40468c0edc705a6345591110b 344 Pfam PF01207 Dihydrouridine synthase (Dus) 15 317 6.8E-81 T 29-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CDC59_RS21725 c0650a16d2de7330893af29823a2e779 533 Pfam PF00672 HAMP domain 246 293 2.1E-13 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CDC59_RS21725 c0650a16d2de7330893af29823a2e779 533 SUPERFAMILY SSF158472 245 293 1.26E-10 T 29-03-2018 CDC59_RS21725 c0650a16d2de7330893af29823a2e779 533 SMART SM00388 298 362 3.4E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS21725 c0650a16d2de7330893af29823a2e779 533 Pfam PF00512 His Kinase A (phospho-acceptor) domain 298 360 1.3E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS21725 c0650a16d2de7330893af29823a2e779 533 SMART SM00387 411 523 7.4E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS21725 c0650a16d2de7330893af29823a2e779 533 SMART SM00304 245 297 9.4E-14 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CDC59_RS21725 c0650a16d2de7330893af29823a2e779 533 PRINTS PR00344 Bacterial sensor protein C-terminal signature 483 501 4.6E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS21725 c0650a16d2de7330893af29823a2e779 533 PRINTS PR00344 Bacterial sensor protein C-terminal signature 466 476 4.6E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS21725 c0650a16d2de7330893af29823a2e779 533 PRINTS PR00344 Bacterial sensor protein C-terminal signature 448 462 4.6E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS21725 c0650a16d2de7330893af29823a2e779 533 Gene3D G3DSA:1.10.287.130 288 357 5.0E-14 T 29-03-2018 CDC59_RS21725 c0650a16d2de7330893af29823a2e779 533 SUPERFAMILY SSF55874 351 525 7.73E-41 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS21725 c0650a16d2de7330893af29823a2e779 533 SUPERFAMILY SSF47384 281 360 4.32E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CDC59_RS21725 c0650a16d2de7330893af29823a2e779 533 Gene3D G3DSA:3.30.565.10 366 532 1.6E-39 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS21725 c0650a16d2de7330893af29823a2e779 533 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 411 520 1.3E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS08155 b67c890705fa56be9b090e24660686d1 367 Pfam PF13464 Domain of unknown function (DUF4115) 292 366 1.7E-19 T 29-03-2018 IPR025194 Domain of unknown function DUF4115 CDC59_RS08155 b67c890705fa56be9b090e24660686d1 367 SUPERFAMILY SSF47413 33 100 6.52E-6 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDC59_RS08155 b67c890705fa56be9b090e24660686d1 367 Gene3D G3DSA:1.10.260.40 22 111 3.8E-10 T 29-03-2018 CDC59_RS08155 b67c890705fa56be9b090e24660686d1 367 Pfam PF13413 Helix-turn-helix domain 38 98 6.9E-17 T 29-03-2018 CDC59_RS22115 60220e94e1630e79ad58f06d1f21b1a2 221 Gene3D G3DSA:3.50.30.40 4 173 9.1E-46 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CDC59_RS22115 60220e94e1630e79ad58f06d1f21b1a2 221 SUPERFAMILY SSF89562 15 181 6.93E-39 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CDC59_RS22115 60220e94e1630e79ad58f06d1f21b1a2 221 Pfam PF03737 Aldolase/RraA 17 171 3.4E-33 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CDC59_RS02290 c768132b52f9bdcc6e29d8aba843c61f 102 Gene3D G3DSA:2.30.30.30 2 90 6.3E-27 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 CDC59_RS02290 c768132b52f9bdcc6e29d8aba843c61f 102 SUPERFAMILY SSF50104 3 97 1.12E-26 T 29-03-2018 IPR008991 Translation protein SH3-like domain CDC59_RS02290 c768132b52f9bdcc6e29d8aba843c61f 102 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 37 99 1.1E-20 T 29-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS02290 c768132b52f9bdcc6e29d8aba843c61f 102 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 2 94 18.751 T 29-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS02290 c768132b52f9bdcc6e29d8aba843c61f 102 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 1 99 1.2E-28 T 29-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS02290 c768132b52f9bdcc6e29d8aba843c61f 102 SMART SM00739 3 30 2.3E-4 T 29-03-2018 IPR005824 KOW CDC59_RS05605 b8b97d4a6a145ecf08b321e4d83bdd9b 639 SMART SM00487 19 213 0.0017 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CDC59_RS05605 b8b97d4a6a145ecf08b321e4d83bdd9b 639 Gene3D G3DSA:3.40.50.300 20 190 4.8E-13 T 29-03-2018 CDC59_RS05605 b8b97d4a6a145ecf08b321e4d83bdd9b 639 SUPERFAMILY SSF52540 35 271 1.65E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS05605 b8b97d4a6a145ecf08b321e4d83bdd9b 639 SUPERFAMILY SSF52540 301 382 1.65E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS05605 b8b97d4a6a145ecf08b321e4d83bdd9b 639 Gene3D G3DSA:3.40.50.300 221 414 1.1E-8 T 29-03-2018 CDC59_RS23385 060d1f50c0a747b86fe718faeb0a4f04 73 Gene3D G3DSA:3.30.1580.10 4 66 4.4E-8 T 29-03-2018 CDC59_RS20470 16410c8ca78a312c69c848f49d87d957 250 SUPERFAMILY SSF51735 7 220 1.98E-59 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS20470 16410c8ca78a312c69c848f49d87d957 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 2.7E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS20470 16410c8ca78a312c69c848f49d87d957 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 2.7E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS20470 16410c8ca78a312c69c848f49d87d957 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 2.7E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS20470 16410c8ca78a312c69c848f49d87d957 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 2.7E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS20470 16410c8ca78a312c69c848f49d87d957 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.7E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS20470 16410c8ca78a312c69c848f49d87d957 250 Pfam PF00106 short chain dehydrogenase 7 185 7.6E-47 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS20470 16410c8ca78a312c69c848f49d87d957 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 164 5.4E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS20470 16410c8ca78a312c69c848f49d87d957 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 125 133 5.4E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS20470 16410c8ca78a312c69c848f49d87d957 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 72 83 5.4E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS20470 16410c8ca78a312c69c848f49d87d957 250 Gene3D G3DSA:3.40.50.720 2 248 4.0E-56 T 29-03-2018 CDC59_RS15845 48a16f6b4455fa954b0123cbc0bd7c62 495 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 9 487 95.604 T 29-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CDC59_RS15845 48a16f6b4455fa954b0123cbc0bd7c62 495 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 11 487 6.5E-178 T 29-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CDC59_RS15845 48a16f6b4455fa954b0123cbc0bd7c62 495 SUPERFAMILY SSF75304 4 493 2.75E-163 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CDC59_RS15845 48a16f6b4455fa954b0123cbc0bd7c62 495 Gene3D G3DSA:3.90.1300.10 1 495 5.9E-176 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CDC59_RS15845 48a16f6b4455fa954b0123cbc0bd7c62 495 Pfam PF01425 Amidase 22 476 2.2E-153 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CDC59_RS15845 48a16f6b4455fa954b0123cbc0bd7c62 495 ProSitePatterns PS00571 Amidases signature. 148 179 - T 29-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CDC59_RS02375 b2a11f8e716606907e329441792c5bec 112 SUPERFAMILY SSF54913 5 107 4.45E-34 T 29-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta CDC59_RS02375 b2a11f8e716606907e329441792c5bec 112 Pfam PF03091 CutA1 divalent ion tolerance protein 9 104 7.2E-32 T 29-03-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 CDC59_RS02375 b2a11f8e716606907e329441792c5bec 112 Gene3D G3DSA:3.30.70.120 1 108 3.0E-34 T 29-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CDC59_RS11715 d3c000680c6548307e36115a3f21fce2 156 Pfam PF01575 MaoC like domain 18 119 1.5E-18 T 29-03-2018 IPR002539 MaoC-like domain CDC59_RS11715 d3c000680c6548307e36115a3f21fce2 156 SUPERFAMILY SSF54637 9 154 5.13E-39 T 29-03-2018 IPR029069 HotDog domain CDC59_RS11715 d3c000680c6548307e36115a3f21fce2 156 Gene3D G3DSA:3.10.129.10 2 147 3.1E-34 T 29-03-2018 CDC59_RS09030 525b0d6012c839fe95e9770116a8e146 299 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 20 73 7.0E-13 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CDC59_RS09030 525b0d6012c839fe95e9770116a8e146 299 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 297 3.6E-32 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS09030 525b0d6012c839fe95e9770116a8e146 299 Gene3D G3DSA:1.10.3720.10 21 286 4.8E-48 T 29-03-2018 CDC59_RS09030 525b0d6012c839fe95e9770116a8e146 299 SUPERFAMILY SSF161098 91 281 3.14E-32 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS22465 42c61ddbbdb9442d497c7ef0f7d42950 296 Pfam PF00561 alpha/beta hydrolase fold 36 278 5.6E-27 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS22465 42c61ddbbdb9442d497c7ef0f7d42950 296 Gene3D G3DSA:3.40.50.1820 6 296 3.1E-51 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS22465 42c61ddbbdb9442d497c7ef0f7d42950 296 SUPERFAMILY SSF53474 13 293 4.45E-68 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS22465 42c61ddbbdb9442d497c7ef0f7d42950 296 PRINTS PR00111 Alpha/beta hydrolase fold signature 238 252 8.8E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS22465 42c61ddbbdb9442d497c7ef0f7d42950 296 PRINTS PR00111 Alpha/beta hydrolase fold signature 61 76 8.8E-6 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS06145 cfb4ba7a6b3f47e882c4cc05383a5c98 149 Gene3D G3DSA:1.10.10.410 91 147 1.5E-19 T 29-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal CDC59_RS06145 cfb4ba7a6b3f47e882c4cc05383a5c98 149 SUPERFAMILY SSF89095 1 146 3.3E-44 T 29-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 CDC59_RS06145 cfb4ba7a6b3f47e882c4cc05383a5c98 149 Gene3D G3DSA:1.10.1510.10 1 90 5.0E-32 T 29-03-2018 CDC59_RS06145 cfb4ba7a6b3f47e882c4cc05383a5c98 149 Pfam PF09424 Yqey-like protein 4 146 4.8E-57 T 29-03-2018 IPR019004 Uncharacterised domain YOR215C, mitochondrial CDC59_RS01085 32a82f7949babbb65f9419048a51b7df 110 Gene3D G3DSA:1.10.260.40 28 108 1.4E-11 T 29-03-2018 CDC59_RS01085 32a82f7949babbb65f9419048a51b7df 110 Pfam PF13560 Helix-turn-helix domain 55 108 6.9E-9 T 29-03-2018 CDC59_RS01085 32a82f7949babbb65f9419048a51b7df 110 SUPERFAMILY SSF47413 55 105 1.23E-9 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDC59_RS01085 32a82f7949babbb65f9419048a51b7df 110 SMART SM00530 54 108 3.4E-4 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDC59_RS01640 f6bec7ebfc76dd4d69d3c31c8b9907ca 270 Hamap MF_00601 Ethanolamine ammonia-lyase light chain [eutC]. 7 252 38.786 T 29-03-2018 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 CDC59_RS01640 f6bec7ebfc76dd4d69d3c31c8b9907ca 270 Pfam PF05985 Ethanolamine ammonia-lyase light chain (EutC) 15 252 1.1E-95 T 29-03-2018 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 CDC59_RS01640 f6bec7ebfc76dd4d69d3c31c8b9907ca 270 PIRSF PIRSF018982 1 261 5.6E-107 T 29-03-2018 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 CDC59_RS04535 0f658274120bfc73022c205c2e3a3f96 110 Pfam PF00581 Rhodanese-like domain 10 101 4.2E-13 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS04535 0f658274120bfc73022c205c2e3a3f96 110 Gene3D G3DSA:3.40.250.10 1 110 2.1E-22 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS04535 0f658274120bfc73022c205c2e3a3f96 110 SMART SM00450 7 105 2.0E-15 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS04535 0f658274120bfc73022c205c2e3a3f96 110 SUPERFAMILY SSF52821 3 106 4.32E-25 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS06345 76e0791166a0c7b69b950ce06e05d1c1 186 Pfam PF13211 Protein of unknown function (DUF4019) 74 164 5.7E-8 T 29-03-2018 IPR025091 Protein of unknown function DUF4019 CDC59_RS06585 1dca6f4b32a85e45efccd4874330db97 125 Gene3D G3DSA:3.30.70.100 8 111 1.1E-17 T 29-03-2018 CDC59_RS06585 1dca6f4b32a85e45efccd4874330db97 125 SUPERFAMILY SSF54909 19 105 1.04E-19 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CDC59_RS06585 1dca6f4b32a85e45efccd4874330db97 125 Pfam PF03992 Antibiotic biosynthesis monooxygenase 20 95 5.2E-13 T 29-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CDC59_RS09880 67e8d003517b5ba714db4d3e8db09fa0 442 PIRSF PIRSF020818 1 416 4.8E-171 T 29-03-2018 IPR010915 Polyhydroxyalkanoate depolymerase CDC59_RS09880 67e8d003517b5ba714db4d3e8db09fa0 442 Pfam PF06850 PHB de-polymerase C-terminus 205 405 1.9E-85 T 29-03-2018 IPR009656 PHB de-polymerase, C-terminal CDC59_RS09880 67e8d003517b5ba714db4d3e8db09fa0 442 TIGRFAM TIGR01849 PHB_depoly_PhaZ: polyhydroxyalkanoate depolymerase, intracellular 6 405 2.8E-155 T 29-03-2018 IPR010915 Polyhydroxyalkanoate depolymerase CDC59_RS09880 67e8d003517b5ba714db4d3e8db09fa0 442 SUPERFAMILY SSF53474 79 401 5.91E-28 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS09880 67e8d003517b5ba714db4d3e8db09fa0 442 Gene3D G3DSA:3.40.50.1820 69 407 1.2E-13 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS00060 36b662c1481fbd337ad2a899906caf87 514 Gene3D G3DSA:1.20.1600.10 26 486 7.9E-102 T 29-03-2018 CDC59_RS00060 36b662c1481fbd337ad2a899906caf87 514 SUPERFAMILY SSF56954 71 482 7.06E-116 T 29-03-2018 CDC59_RS00060 36b662c1481fbd337ad2a899906caf87 514 SUPERFAMILY SSF56954 2 38 7.06E-116 T 29-03-2018 CDC59_RS00060 36b662c1481fbd337ad2a899906caf87 514 Pfam PF02321 Outer membrane efflux protein 80 269 3.8E-24 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CDC59_RS00060 36b662c1481fbd337ad2a899906caf87 514 Pfam PF02321 Outer membrane efflux protein 302 478 1.0E-26 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CDC59_RS00060 36b662c1481fbd337ad2a899906caf87 514 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 18 480 2.9E-120 T 29-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 CDC59_RS06815 2c1c0eda52c907830e15f393e27b1057 603 Gene3D G3DSA:3.40.50.300 12 269 4.0E-58 T 29-03-2018 CDC59_RS06815 2c1c0eda52c907830e15f393e27b1057 603 Pfam PF00270 DEAD/DEAH box helicase 54 243 2.9E-47 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CDC59_RS06815 2c1c0eda52c907830e15f393e27b1057 603 Gene3D G3DSA:3.40.50.300 270 432 6.2E-45 T 29-03-2018 CDC59_RS06815 2c1c0eda52c907830e15f393e27b1057 603 Pfam PF00271 Helicase conserved C-terminal domain 283 388 3.1E-28 T 29-03-2018 IPR001650 Helicase, C-terminal CDC59_RS06815 2c1c0eda52c907830e15f393e27b1057 603 SUPERFAMILY SSF52540 122 409 1.39E-72 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS06815 2c1c0eda52c907830e15f393e27b1057 603 SMART SM00487 49 265 6.9E-58 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CDC59_RS06815 2c1c0eda52c907830e15f393e27b1057 603 SMART SM00490 307 388 5.4E-33 T 29-03-2018 IPR001650 Helicase, C-terminal CDC59_RS06815 2c1c0eda52c907830e15f393e27b1057 603 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 201 209 - T 29-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site CDC59_RS18725 27097ad0e65893518e7f72623a98d222 583 Gene3D G3DSA:1.25.40.10 249 488 4.0E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS18725 27097ad0e65893518e7f72623a98d222 583 SUPERFAMILY SSF48452 43 208 5.81E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS18725 27097ad0e65893518e7f72623a98d222 583 Pfam PF14559 Tetratricopeptide repeat 55 115 1.0E-5 T 29-03-2018 CDC59_RS18725 27097ad0e65893518e7f72623a98d222 583 Gene3D G3DSA:1.25.40.10 25 106 5.9E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS18725 27097ad0e65893518e7f72623a98d222 583 Gene3D G3DSA:1.25.40.10 107 243 6.5E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS18725 27097ad0e65893518e7f72623a98d222 583 Pfam PF13283 Bacteriophage N adsorption protein A C-term 408 579 2.7E-69 T 29-03-2018 IPR025137 Bacteriophage N4 adsorption protein A, C-terminal CDC59_RS07595 b73ad3dbdd715d2bb1d5041ddc0f77ca 164 SMART SM00347 39 142 1.8E-16 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS07595 b73ad3dbdd715d2bb1d5041ddc0f77ca 164 Pfam PF12802 MarR family 44 103 9.7E-11 T 29-03-2018 CDC59_RS07595 b73ad3dbdd715d2bb1d5041ddc0f77ca 164 SUPERFAMILY SSF46785 15 150 2.09E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS07595 b73ad3dbdd715d2bb1d5041ddc0f77ca 164 Gene3D G3DSA:1.10.10.10 14 153 6.7E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS21745 f2b60dd4fcdee83ac24d6f76bfc66a1b 317 Pfam PF09916 Uncharacterized protein conserved in bacteria (DUF2145) 63 273 2.1E-58 T 29-03-2018 IPR014547 Uncharacterised conserved protein UCP028477 CDC59_RS21745 f2b60dd4fcdee83ac24d6f76bfc66a1b 317 PIRSF PIRSF028477 1 307 1.0E-114 T 29-03-2018 IPR014547 Uncharacterised conserved protein UCP028477 CDC59_RS03390 ac9b00c7973a10bb6c7a0b4b1839f090 197 PRINTS PR00624 Histone H5 signature 101 118 5.6E-5 T 29-03-2018 IPR005819 Histone H5 GO:0000786|GO:0003677|GO:0006334 CDC59_RS03390 ac9b00c7973a10bb6c7a0b4b1839f090 197 PRINTS PR00624 Histone H5 signature 69 83 5.6E-5 T 29-03-2018 IPR005819 Histone H5 GO:0000786|GO:0003677|GO:0006334 CDC59_RS03390 ac9b00c7973a10bb6c7a0b4b1839f090 197 PRINTS PR00624 Histone H5 signature 123 142 5.6E-5 T 29-03-2018 IPR005819 Histone H5 GO:0000786|GO:0003677|GO:0006334 CDC59_RS03390 ac9b00c7973a10bb6c7a0b4b1839f090 197 Pfam PF07382 Histone H1-like nucleoprotein HC2 1 196 4.4E-16 T 29-03-2018 IPR009970 Histone H1-like nucleoprotein HC2 GO:0003677|GO:0030261 CDC59_RS07060 73e5dcda879a5033e99d8b29f463f5f8 144 Pfam PF08897 Domain of unknown function (DUF1841) 6 139 3.0E-63 T 29-03-2018 IPR014993 Protein of unknown function DUF1841 CDC59_RS08090 b6b4b0c7429fa094a4669c6bf563cf74 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 1.2E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDC59_RS08090 b6b4b0c7429fa094a4669c6bf563cf74 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 1.2E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDC59_RS08090 b6b4b0c7429fa094a4669c6bf563cf74 209 SUPERFAMILY SSF48498 91 204 8.9E-25 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CDC59_RS08090 b6b4b0c7429fa094a4669c6bf563cf74 209 Gene3D G3DSA:1.10.10.60 13 69 1.1E-18 T 29-03-2018 CDC59_RS08090 b6b4b0c7429fa094a4669c6bf563cf74 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 64 1.2E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDC59_RS08090 b6b4b0c7429fa094a4669c6bf563cf74 209 Gene3D G3DSA:1.10.357.10 70 205 1.5E-28 T 29-03-2018 CDC59_RS08090 b6b4b0c7429fa094a4669c6bf563cf74 209 SUPERFAMILY SSF46689 16 85 3.13E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS08090 b6b4b0c7429fa094a4669c6bf563cf74 209 Pfam PF16925 Bacterial transcriptional repressor C-terminal 94 192 4.3E-8 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CDC59_RS16330 63065b5fa61558bc23f0b2fc922aff32 670 Pfam PF11992 Domain of unknown function (DUF3488) 17 339 1.5E-94 T 29-03-2018 IPR021878 Protein of unknown function DUF3488 CDC59_RS16330 63065b5fa61558bc23f0b2fc922aff32 670 Pfam PF13559 Domain of unknown function (DUF4129) 592 660 1.0E-8 T 29-03-2018 IPR025403 Domain of unknown function DUF4129 CDC59_RS16330 63065b5fa61558bc23f0b2fc922aff32 670 SUPERFAMILY SSF54001 287 611 2.94E-63 T 29-03-2018 CDC59_RS16330 63065b5fa61558bc23f0b2fc922aff32 670 SMART SM00460 416 487 4.2E-25 T 29-03-2018 IPR002931 Transglutaminase-like CDC59_RS16330 63065b5fa61558bc23f0b2fc922aff32 670 Pfam PF01841 Transglutaminase-like superfamily 371 485 1.6E-25 T 29-03-2018 IPR002931 Transglutaminase-like CDC59_RS16330 63065b5fa61558bc23f0b2fc922aff32 670 Gene3D G3DSA:3.90.260.10 394 517 1.3E-20 T 29-03-2018 IPR002931 Transglutaminase-like CDC59_RS11475 6659ae5890ce45f254e91ebf5430e37b 121 SUPERFAMILY SSF81343 10 121 3.43E-31 T 29-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CDC59_RS11475 6659ae5890ce45f254e91ebf5430e37b 121 TIGRFAM TIGR02968 succ_dehyd_anc: succinate dehydrogenase, hydrophobic membrane anchor protein 15 119 2.6E-39 T 29-03-2018 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 CDC59_RS11475 6659ae5890ce45f254e91ebf5430e37b 121 PIRSF PIRSF000169 7 121 2.5E-41 T 29-03-2018 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 CDC59_RS11475 6659ae5890ce45f254e91ebf5430e37b 121 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 4 107 7.6E-15 T 29-03-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CDC59_RS11475 6659ae5890ce45f254e91ebf5430e37b 121 Gene3D G3DSA:1.20.1300.10 9 121 1.9E-21 T 29-03-2018 CDC59_RS22935 cf16cc9fd058b87ec909292ca14f24a7 404 SUPERFAMILY SSF103473 16 403 1.83E-73 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS22935 cf16cc9fd058b87ec909292ca14f24a7 404 Gene3D G3DSA:1.20.1250.20 214 404 1.4E-20 T 29-03-2018 CDC59_RS22935 cf16cc9fd058b87ec909292ca14f24a7 404 Gene3D G3DSA:1.20.1250.20 16 207 6.7E-37 T 29-03-2018 CDC59_RS22935 cf16cc9fd058b87ec909292ca14f24a7 404 ProSitePatterns PS00216 Sugar transport proteins signature 1. 72 89 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CDC59_RS22935 cf16cc9fd058b87ec909292ca14f24a7 404 Pfam PF07690 Major Facilitator Superfamily 23 255 1.3E-35 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDC59_RS17195 37c734a30d198f9063f71db620ac430e 154 TIGRFAM TIGR02473 flagell_FliJ: flagellar export protein FliJ 7 142 7.1E-29 T 29-03-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 CDC59_RS17195 37c734a30d198f9063f71db620ac430e 154 PRINTS PR01004 Flagellar FliJ protein signature 65 86 1.5E-9 T 29-03-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 CDC59_RS17195 37c734a30d198f9063f71db620ac430e 154 PRINTS PR01004 Flagellar FliJ protein signature 6 28 1.5E-9 T 29-03-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 CDC59_RS17195 37c734a30d198f9063f71db620ac430e 154 PRINTS PR01004 Flagellar FliJ protein signature 128 148 1.5E-9 T 29-03-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 CDC59_RS17195 37c734a30d198f9063f71db620ac430e 154 PRINTS PR01004 Flagellar FliJ protein signature 46 63 1.5E-9 T 29-03-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 CDC59_RS17195 37c734a30d198f9063f71db620ac430e 154 PRINTS PR01004 Flagellar FliJ protein signature 88 109 1.5E-9 T 29-03-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 CDC59_RS17195 37c734a30d198f9063f71db620ac430e 154 Pfam PF02050 Flagellar FliJ protein 21 141 9.9E-28 T 29-03-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 CDC59_RS17195 37c734a30d198f9063f71db620ac430e 154 PIRSF PIRSF019404 1 150 2.0E-46 T 29-03-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 CDC59_RS21970 a032d6fd4fc022c959c76bdadd6967bc 365 Pfam PF11380 Stealth protein CR2, conserved region 2 64 163 1.0E-32 T 29-03-2018 IPR021520 Stealth protein CR2, conserved region 2 GO:0016772 CDC59_RS21970 a032d6fd4fc022c959c76bdadd6967bc 365 Pfam PF17101 Stealth protein CR1, conserved region 1 21 46 4.8E-14 T 29-03-2018 IPR031358 Stealth protein CR1, conserved region 1 CDC59_RS20455 1159053d1a042691a53d52b83b99615b 340 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 24 301 4.7E-83 T 29-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CDC59_RS20455 1159053d1a042691a53d52b83b99615b 340 SMART SM00797 23 319 2.8E-138 T 29-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CDC59_RS20455 1159053d1a042691a53d52b83b99615b 340 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 1 326 3.0E-88 T 29-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CDC59_RS20455 1159053d1a042691a53d52b83b99615b 340 SUPERFAMILY SSF50891 196 309 7.59E-12 T 29-03-2018 IPR029000 Cyclophilin-like domain CDC59_RS03005 63d40143f6b7d82976c897fc7e5195c9 325 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 319 3.6E-42 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS03005 63d40143f6b7d82976c897fc7e5195c9 325 Gene3D G3DSA:1.10.3720.10 4 308 9.9E-42 T 29-03-2018 CDC59_RS03005 63d40143f6b7d82976c897fc7e5195c9 325 SUPERFAMILY SSF161098 90 307 1.31E-21 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS23635 1f6452f16520033349197d04c1f17eda 154 Pfam PF03743 Bacterial conjugation TrbI-like protein 48 135 1.2E-7 T 29-03-2018 IPR005498 Type IV secretion system, VirB10 / TraB / TrbI CDC59_RS06180 3bcb61181836150b7119bc8e27132805 495 SUPERFAMILY SSF52540 91 380 3.18E-78 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS06180 3bcb61181836150b7119bc8e27132805 495 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 170 178 - T 29-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site CDC59_RS06180 3bcb61181836150b7119bc8e27132805 495 Pfam PF00271 Helicase conserved C-terminal domain 251 360 2.3E-29 T 29-03-2018 IPR001650 Helicase, C-terminal CDC59_RS06180 3bcb61181836150b7119bc8e27132805 495 SMART SM00487 34 239 4.3E-63 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CDC59_RS06180 3bcb61181836150b7119bc8e27132805 495 SMART SM00490 279 360 9.4E-32 T 29-03-2018 IPR001650 Helicase, C-terminal CDC59_RS06180 3bcb61181836150b7119bc8e27132805 495 Gene3D G3DSA:3.40.50.300 1 242 2.4E-62 T 29-03-2018 CDC59_RS06180 3bcb61181836150b7119bc8e27132805 495 Pfam PF00270 DEAD/DEAH box helicase 39 213 9.2E-55 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CDC59_RS06180 3bcb61181836150b7119bc8e27132805 495 Gene3D G3DSA:3.40.50.300 243 482 3.5E-47 T 29-03-2018 CDC59_RS02725 21fcd0fcd1d4f5374af24c6727bb9092 699 SUPERFAMILY SSF56935 28 699 8.33E-79 T 29-03-2018 CDC59_RS02725 21fcd0fcd1d4f5374af24c6727bb9092 699 Pfam PF00593 TonB dependent receptor 240 697 8.2E-36 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CDC59_RS02725 21fcd0fcd1d4f5374af24c6727bb9092 699 Gene3D G3DSA:2.40.170.20 160 699 1.5E-45 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CDC59_RS02725 21fcd0fcd1d4f5374af24c6727bb9092 699 Pfam PF07715 TonB-dependent Receptor Plug Domain 53 162 2.3E-11 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CDC59_RS02725 21fcd0fcd1d4f5374af24c6727bb9092 699 Gene3D G3DSA:2.170.130.10 26 159 9.7E-13 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CDC59_RS17545 778f65403e3508c7ddf7902c73d7cc0b 717 Gene3D G3DSA:1.25.40.10 537 637 9.1E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS17545 778f65403e3508c7ddf7902c73d7cc0b 717 Gene3D G3DSA:3.10.350.10 202 342 5.5E-9 T 29-03-2018 CDC59_RS17545 778f65403e3508c7ddf7902c73d7cc0b 717 TIGRFAM TIGR03505 FimV_core: FimV N-terminal domain 225 296 1.7E-14 T 29-03-2018 IPR020012 Motility protein FimV, N-terminal CDC59_RS04890 3ed66307277d794c85a603df6473b982 186 Gene3D G3DSA:3.30.1060.10 1 179 3.4E-64 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CDC59_RS04890 3ed66307277d794c85a603df6473b982 186 Pfam PF01625 Peptide methionine sulfoxide reductase 9 165 1.8E-57 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CDC59_RS04890 3ed66307277d794c85a603df6473b982 186 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 7 170 35.716 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CDC59_RS04890 3ed66307277d794c85a603df6473b982 186 SUPERFAMILY SSF55068 5 177 4.19E-68 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CDC59_RS04890 3ed66307277d794c85a603df6473b982 186 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 8 165 1.4E-52 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CDC59_RS16845 a594037636d8f11e6959183705a5b71f 476 Pfam PF02321 Outer membrane efflux protein 283 459 1.4E-27 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CDC59_RS16845 a594037636d8f11e6959183705a5b71f 476 Pfam PF02321 Outer membrane efflux protein 58 250 1.9E-20 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CDC59_RS16845 a594037636d8f11e6959183705a5b71f 476 Gene3D G3DSA:1.20.1600.10 15 467 2.9E-99 T 29-03-2018 CDC59_RS16845 a594037636d8f11e6959183705a5b71f 476 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 9 461 5.2E-119 T 29-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 CDC59_RS16845 a594037636d8f11e6959183705a5b71f 476 SUPERFAMILY SSF56954 4 463 2.49E-109 T 29-03-2018 CDC59_RS02070 42bd93785a8f66929b2d85c45d841f45 285 Pfam PF05235 CHAD domain 19 246 5.3E-44 T 29-03-2018 IPR007899 CHAD domain CDC59_RS02070 42bd93785a8f66929b2d85c45d841f45 285 SMART SM00880 16 279 6.4E-53 T 29-03-2018 IPR007899 CHAD domain CDC59_RS08635 88ed94f63b933154fa314f56ef1b9701 86 SUPERFAMILY SSF51182 19 84 3.31E-10 T 29-03-2018 IPR011051 RmlC-like cupin domain CDC59_RS08635 88ed94f63b933154fa314f56ef1b9701 86 Gene3D G3DSA:2.60.120.10 2 80 3.9E-7 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CDC59_RS22085 d22fe3ecccf5c64af5fd30b5e1adc3cf 272 Gene3D G3DSA:3.40.50.1820 6 268 4.5E-35 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS22085 d22fe3ecccf5c64af5fd30b5e1adc3cf 272 SUPERFAMILY SSF53474 17 265 3.02E-40 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS22085 d22fe3ecccf5c64af5fd30b5e1adc3cf 272 Pfam PF12697 Alpha/beta hydrolase family 35 256 5.3E-20 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS22130 e139f60fca269799babd1e925a9ba7f2 710 Pfam PF14496 C-terminal novel E3 ligase, LRR-interacting 335 548 5.7E-36 T 29-03-2018 IPR029487 Novel E3 ligase domain GO:0004842|GO:0016567 CDC59_RS22130 e139f60fca269799babd1e925a9ba7f2 710 Gene3D G3DSA:1.20.58.360 419 544 1.1E-10 T 29-03-2018 CDC59_RS14605 09dacb1e4ad1db63373f0996b4ea047f 171 SUPERFAMILY SSF52949 3 168 2.35E-64 T 29-03-2018 CDC59_RS14605 09dacb1e4ad1db63373f0996b4ea047f 171 Gene3D G3DSA:3.40.220.10 2 171 2.9E-72 T 29-03-2018 CDC59_RS14605 09dacb1e4ad1db63373f0996b4ea047f 171 Pfam PF01661 Macro domain 24 136 8.5E-45 T 29-03-2018 IPR002589 Macro domain CDC59_RS14605 09dacb1e4ad1db63373f0996b4ea047f 171 SMART SM00506 7 136 1.7E-48 T 29-03-2018 IPR002589 Macro domain CDC59_RS16035 c3936a7c91bd7a6efd2bcfa6af319d82 265 Gene3D G3DSA:3.40.50.300 1 263 3.1E-57 T 29-03-2018 CDC59_RS16035 c3936a7c91bd7a6efd2bcfa6af319d82 265 Pfam PF00005 ABC transporter 17 178 5.2E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS16035 c3936a7c91bd7a6efd2bcfa6af319d82 265 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS16035 c3936a7c91bd7a6efd2bcfa6af319d82 265 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 226 248 8.3E-13 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CDC59_RS16035 c3936a7c91bd7a6efd2bcfa6af319d82 265 SUPERFAMILY SSF52540 2 249 1.6E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS16035 c3936a7c91bd7a6efd2bcfa6af319d82 265 SMART SM00382 26 225 2.9E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS19675 46fde6fc1fd3628cb047300760282ed1 377 Pfam PF13503 Domain of unknown function (DUF4123) 55 199 8.7E-15 T 29-03-2018 IPR025391 Domain of unknown function DUF4123 CDC59_RS15425 d8d2fbdedc7a21231c634db49d61d36c 251 Pfam PF02698 DUF218 domain 69 229 7.3E-29 T 29-03-2018 IPR003848 Domain of unknown function DUF218 CDC59_RS15425 d8d2fbdedc7a21231c634db49d61d36c 251 Gene3D G3DSA:3.40.50.620 62 206 8.9E-29 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDC59_RS14980 2d317845216db0dc353f91cacd86b7ba 535 Pfam PF01039 Carboxyl transferase domain 48 524 6.5E-151 T 29-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 CDC59_RS14980 2d317845216db0dc353f91cacd86b7ba 535 SUPERFAMILY SSF52096 237 517 9.33E-89 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CDC59_RS14980 2d317845216db0dc353f91cacd86b7ba 535 Gene3D G3DSA:3.90.226.10 9 273 3.1E-71 T 29-03-2018 CDC59_RS14980 2d317845216db0dc353f91cacd86b7ba 535 SUPERFAMILY SSF52096 23 271 3.47E-72 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CDC59_RS14980 2d317845216db0dc353f91cacd86b7ba 535 Gene3D G3DSA:3.90.226.10 274 530 8.3E-71 T 29-03-2018 CDC59_RS04900 35feb11922541e0df52ffe9e8c8065af 406 Pfam PF02353 Mycolic acid cyclopropane synthetase 115 385 1.0E-102 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS04900 35feb11922541e0df52ffe9e8c8065af 406 Gene3D G3DSA:3.40.50.150 111 389 4.1E-66 T 29-03-2018 CDC59_RS04900 35feb11922541e0df52ffe9e8c8065af 406 SUPERFAMILY SSF53335 123 389 1.51E-79 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS04900 35feb11922541e0df52ffe9e8c8065af 406 PIRSF PIRSF003085 7 406 1.4E-130 T 29-03-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 CDC59_RS20215 3baed9c6b6c5ee265421d8fba592cafc 269 TIGRFAM TIGR02544 III_secr_YscJ: type III secretion apparatus lipoprotein, YscJ/HrcJ family 15 199 2.1E-68 T 29-03-2018 IPR003282 Type III secretion system lipoprotein HrcJ/YscJ GO:0009306 CDC59_RS20215 3baed9c6b6c5ee265421d8fba592cafc 269 Pfam PF01514 Secretory protein of YscJ/FliF family 14 194 6.9E-29 T 29-03-2018 IPR006182 Secretory protein YscJ/FliF CDC59_RS20215 3baed9c6b6c5ee265421d8fba592cafc 269 Gene3D G3DSA:3.30.70.1530 30 98 1.7E-20 T 29-03-2018 CDC59_RS20215 3baed9c6b6c5ee265421d8fba592cafc 269 PRINTS PR01338 Type III secretion system outer membrane K protein family signature 85 98 4.7E-25 T 29-03-2018 IPR003282 Type III secretion system lipoprotein HrcJ/YscJ GO:0009306 CDC59_RS20215 3baed9c6b6c5ee265421d8fba592cafc 269 PRINTS PR01338 Type III secretion system outer membrane K protein family signature 105 120 4.7E-25 T 29-03-2018 IPR003282 Type III secretion system lipoprotein HrcJ/YscJ GO:0009306 CDC59_RS20215 3baed9c6b6c5ee265421d8fba592cafc 269 PRINTS PR01338 Type III secretion system outer membrane K protein family signature 125 138 4.7E-25 T 29-03-2018 IPR003282 Type III secretion system lipoprotein HrcJ/YscJ GO:0009306 CDC59_RS20215 3baed9c6b6c5ee265421d8fba592cafc 269 PRINTS PR01338 Type III secretion system outer membrane K protein family signature 173 185 4.7E-25 T 29-03-2018 IPR003282 Type III secretion system lipoprotein HrcJ/YscJ GO:0009306 CDC59_RS20215 3baed9c6b6c5ee265421d8fba592cafc 269 PRINTS PR01338 Type III secretion system outer membrane K protein family signature 32 42 4.7E-25 T 29-03-2018 IPR003282 Type III secretion system lipoprotein HrcJ/YscJ GO:0009306 CDC59_RS05870 5e8ba9195902816f048ad70f4664fea6 176 Pfam PF13411 MerR HTH family regulatory protein 6 72 4.6E-13 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CDC59_RS05870 5e8ba9195902816f048ad70f4664fea6 176 SMART SM00422 5 74 3.9E-15 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CDC59_RS05870 5e8ba9195902816f048ad70f4664fea6 176 Gene3D G3DSA:1.10.1660.10 60 154 1.6E-12 T 29-03-2018 CDC59_RS05870 5e8ba9195902816f048ad70f4664fea6 176 Gene3D G3DSA:1.10.1660.10 1 59 4.8E-19 T 29-03-2018 CDC59_RS05870 5e8ba9195902816f048ad70f4664fea6 176 SUPERFAMILY SSF46955 4 115 8.06E-22 T 29-03-2018 IPR009061 Putative DNA-binding domain CDC59_RS12030 51589b77509297b047e10defb5a641c4 389 Pfam PF14279 HNH endonuclease 14 66 6.9E-16 T 29-03-2018 IPR029471 HNH endonuclease 5 CDC59_RS15460 3000dc9cfc445571cf1ede8af37eee24 225 Pfam PF00156 Phosphoribosyl transferase domain 47 161 1.4E-14 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CDC59_RS15460 3000dc9cfc445571cf1ede8af37eee24 225 Gene3D G3DSA:3.40.50.2020 4 200 3.6E-46 T 29-03-2018 CDC59_RS15460 3000dc9cfc445571cf1ede8af37eee24 225 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 225 32.349 T 29-03-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CDC59_RS15460 3000dc9cfc445571cf1ede8af37eee24 225 SUPERFAMILY SSF53271 7 202 3.59E-45 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CDC59_RS15460 3000dc9cfc445571cf1ede8af37eee24 225 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 14 194 2.5E-53 T 29-03-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CDC59_RS15660 1e21889425daee80c689d2b5492f00b7 113 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 1 105 1.7E-31 T 29-03-2018 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV CDC59_RS08085 6031393ddadd5a7b0744a503a2db6d27 263 SUPERFAMILY SSF161098 57 243 8.24E-29 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS08085 6031393ddadd5a7b0744a503a2db6d27 263 Gene3D G3DSA:1.10.3720.10 9 256 1.9E-23 T 29-03-2018 CDC59_RS08085 6031393ddadd5a7b0744a503a2db6d27 263 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 250 2.0E-24 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS02385 4bc448a03a181bc04ba5e7f513c3ab48 331 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 248 264 2.5E-57 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CDC59_RS02385 4bc448a03a181bc04ba5e7f513c3ab48 331 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 273 288 2.5E-57 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CDC59_RS02385 4bc448a03a181bc04ba5e7f513c3ab48 331 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 156 175 2.5E-57 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CDC59_RS02385 4bc448a03a181bc04ba5e7f513c3ab48 331 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 194 213 2.5E-57 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CDC59_RS02385 4bc448a03a181bc04ba5e7f513c3ab48 331 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 303 322 2.5E-57 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CDC59_RS02385 4bc448a03a181bc04ba5e7f513c3ab48 331 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 125 139 2.5E-57 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CDC59_RS02385 4bc448a03a181bc04ba5e7f513c3ab48 331 PIRSF PIRSF001415 1 331 5.4E-145 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CDC59_RS02385 4bc448a03a181bc04ba5e7f513c3ab48 331 SMART SM01004 5 329 4.4E-237 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CDC59_RS02385 4bc448a03a181bc04ba5e7f513c3ab48 331 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 248 260 - T 29-03-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CDC59_RS02385 4bc448a03a181bc04ba5e7f513c3ab48 331 Pfam PF00490 Delta-aminolevulinic acid dehydratase 8 327 1.9E-137 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CDC59_RS02385 4bc448a03a181bc04ba5e7f513c3ab48 331 Gene3D G3DSA:3.20.20.70 1 331 1.4E-147 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS02385 4bc448a03a181bc04ba5e7f513c3ab48 331 SUPERFAMILY SSF51569 4 330 1.9E-142 T 29-03-2018 CDC59_RS04350 18c3831172d0f48b4ab759e1b67fe931 176 Pfam PF01478 Type IV leader peptidase family 12 114 2.6E-15 T 29-03-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 CDC59_RS16120 9faf15b341dede1e77dc2df716b5e4bf 135 SUPERFAMILY SSF52172 5 128 2.42E-35 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS16120 9faf15b341dede1e77dc2df716b5e4bf 135 Gene3D G3DSA:3.40.50.2300 1 134 5.0E-36 T 29-03-2018 CDC59_RS16120 9faf15b341dede1e77dc2df716b5e4bf 135 SMART SM00448 6 122 1.5E-34 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS16120 9faf15b341dede1e77dc2df716b5e4bf 135 Pfam PF00072 Response regulator receiver domain 9 122 2.9E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS03030 82341bed607ca2c2f2552f2ac16e3b46 372 SUPERFAMILY SSF53822 22 371 5.23E-81 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CDC59_RS03030 82341bed607ca2c2f2552f2ac16e3b46 372 Gene3D G3DSA:3.40.50.2300 16 228 6.0E-41 T 29-03-2018 CDC59_RS03030 82341bed607ca2c2f2552f2ac16e3b46 372 Pfam PF13458 Periplasmic binding protein 22 359 2.8E-70 T 29-03-2018 IPR028081 Leucine-binding protein domain CDC59_RS03030 82341bed607ca2c2f2552f2ac16e3b46 372 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 45 61 4.8E-6 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CDC59_RS03030 82341bed607ca2c2f2552f2ac16e3b46 372 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 23 39 4.8E-6 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CDC59_RS03030 82341bed607ca2c2f2552f2ac16e3b46 372 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 254 272 4.8E-6 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CDC59_RS03030 82341bed607ca2c2f2552f2ac16e3b46 372 Gene3D G3DSA:3.40.50.2300 229 360 7.8E-15 T 29-03-2018 CDC59_RS00555 f2043a00efc05ed4de49a14bf0666cf4 336 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 277 291 3.1E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS00555 f2043a00efc05ed4de49a14bf0666cf4 336 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 307 319 3.1E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS00555 f2043a00efc05ed4de49a14bf0666cf4 336 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 291 307 3.1E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS00555 f2043a00efc05ed4de49a14bf0666cf4 336 SUPERFAMILY SSF46894 271 329 6.12E-15 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CDC59_RS00555 f2043a00efc05ed4de49a14bf0666cf4 336 Gene3D G3DSA:1.10.10.10 159 335 5.2E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS00555 f2043a00efc05ed4de49a14bf0666cf4 336 SMART SM00421 274 331 1.2E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS00555 f2043a00efc05ed4de49a14bf0666cf4 336 Gene3D G3DSA:3.30.450.80 1 158 9.2E-6 T 29-03-2018 CDC59_RS00555 f2043a00efc05ed4de49a14bf0666cf4 336 Pfam PF00196 Bacterial regulatory proteins, luxR family 278 327 4.8E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CDC59_RS16300 6a32315235362c78a1bcdb38be9a4cac 78 Pfam PF05488 PAAR motif 10 69 7.7E-15 T 29-03-2018 IPR008727 PAAR motif CDC59_RS16395 7fc7865232ced9ba47a59572998dcb8a 102 SUPERFAMILY SSF143011 16 101 5.23E-23 T 29-03-2018 IPR035095 Toxin RelE-like domain CDC59_RS16395 7fc7865232ced9ba47a59572998dcb8a 102 Pfam PF15738 Bacterial toxin of type II toxin-antitoxin system, YafQ 16 102 9.2E-29 T 29-03-2018 IPR004386 Toxin-antitoxin system, YafQ-like toxin CDC59_RS16395 7fc7865232ced9ba47a59572998dcb8a 102 PIRSF PIRSF006156 13 102 3.8E-20 T 29-03-2018 IPR004386 Toxin-antitoxin system, YafQ-like toxin CDC59_RS16395 7fc7865232ced9ba47a59572998dcb8a 102 Gene3D G3DSA:3.30.2310.20 15 102 1.6E-22 T 29-03-2018 CDC59_RS16395 7fc7865232ced9ba47a59572998dcb8a 102 TIGRFAM TIGR02385 RelE_StbE: addiction module toxin, RelE/StbE family 18 101 1.3E-23 T 29-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family CDC59_RS10005 bd98d4b1f9a9ec0662ffdb188a36e29f 529 Pfam PF02696 Uncharacterized ACR, YdiU/UPF0061 family 27 497 9.3E-132 T 29-03-2018 IPR003846 Uncharacterised protein family UPF0061 CDC59_RS10005 bd98d4b1f9a9ec0662ffdb188a36e29f 529 Hamap MF_00692 UPF0061 protein YdiU [ydiU]. 21 515 45.438 T 29-03-2018 IPR003846 Uncharacterised protein family UPF0061 CDC59_RS10005 bd98d4b1f9a9ec0662ffdb188a36e29f 529 Gene3D G3DSA:1.10.510.10 226 382 3.0E-6 T 29-03-2018 CDC59_RS07210 be4c44517abe7f0cac4adcafefd7aeba 243 Gene3D G3DSA:3.40.50.10420 62 241 5.3E-40 T 29-03-2018 CDC59_RS07210 be4c44517abe7f0cac4adcafefd7aeba 243 Pfam PF02589 LUD domain 144 240 1.5E-29 T 29-03-2018 IPR003741 LUD domain CDC59_RS07210 be4c44517abe7f0cac4adcafefd7aeba 243 SUPERFAMILY SSF100950 64 240 3.6E-39 T 29-03-2018 CDC59_RS20200 d089a026917250cba584a94ae6fed4bf 354 Gene3D G3DSA:3.40.1690.10 213 348 5.8E-48 T 29-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal CDC59_RS20200 d089a026917250cba584a94ae6fed4bf 354 SUPERFAMILY SSF160544 252 346 2.22E-30 T 29-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal CDC59_RS20200 d089a026917250cba584a94ae6fed4bf 354 TIGRFAM TIGR01404 FlhB_rel_III: type III secretion protein, YscU/HrpY family 3 345 2.6E-122 T 29-03-2018 IPR006307 Type III exporter system, secretion apparatus protein BsaZ GO:0009306|GO:0016021 CDC59_RS20200 d089a026917250cba584a94ae6fed4bf 354 Pfam PF01312 FlhB HrpN YscU SpaS Family 3 342 3.4E-108 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CDC59_RS20200 d089a026917250cba584a94ae6fed4bf 354 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 6 28 2.4E-37 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CDC59_RS20200 d089a026917250cba584a94ae6fed4bf 354 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 203 221 2.4E-37 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CDC59_RS20200 d089a026917250cba584a94ae6fed4bf 354 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 268 283 2.4E-37 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CDC59_RS20200 d089a026917250cba584a94ae6fed4bf 354 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 298 319 2.4E-37 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CDC59_RS20200 d089a026917250cba584a94ae6fed4bf 354 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 223 240 2.4E-37 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CDC59_RS10025 9915145e91259f373e23390b7496906d 265 SUPERFAMILY SSF54534 126 223 5.49E-28 T 29-03-2018 CDC59_RS10025 9915145e91259f373e23390b7496906d 265 SUPERFAMILY SSF109998 26 158 1.37E-17 T 29-03-2018 IPR027304 Trigger factor/SurA domain CDC59_RS10025 9915145e91259f373e23390b7496906d 265 Gene3D G3DSA:3.10.50.40 121 246 2.0E-37 T 29-03-2018 CDC59_RS10025 9915145e91259f373e23390b7496906d 265 Pfam PF00639 PPIC-type PPIASE domain 142 219 2.9E-22 T 29-03-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 CDC59_RS22205 2d4ebf2895310fd0bedcb62fedaed7ba 738 Gene3D G3DSA:3.40.50.1220 328 502 3.0E-7 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CDC59_RS22205 2d4ebf2895310fd0bedcb62fedaed7ba 738 Gene3D G3DSA:3.40.50.970 522 684 0.0018 T 29-03-2018 CDC59_RS22205 2d4ebf2895310fd0bedcb62fedaed7ba 738 Gene3D G3DSA:3.40.50.970 101 327 1.5E-7 T 29-03-2018 CDC59_RS16835 bbd443132128e747befee9055521dd3a 178 SUPERFAMILY SSF46785 3 172 4.18E-37 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS16835 bbd443132128e747befee9055521dd3a 178 Gene3D G3DSA:1.10.10.10 1 89 2.6E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS16835 bbd443132128e747befee9055521dd3a 178 Pfam PF03551 Transcriptional regulator PadR-like family 7 76 1.3E-9 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal CDC59_RS16835 bbd443132128e747befee9055521dd3a 178 Pfam PF10400 Virulence activator alpha C-term 90 172 1.7E-22 T 29-03-2018 IPR018309 Transcription regulator PadR, C-terminal CDC59_RS17795 f5e847d72c657ee699489de6d89f7b85 1238 SUPERFAMILY SSF51445 84 374 1.48E-35 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CDC59_RS17795 f5e847d72c657ee699489de6d89f7b85 1238 Gene3D G3DSA:1.20.58.280 651 720 6.5E-19 T 29-03-2018 CDC59_RS17795 f5e847d72c657ee699489de6d89f7b85 1238 Gene3D G3DSA:3.20.20.80 50 410 1.3E-25 T 29-03-2018 CDC59_RS17795 f5e847d72c657ee699489de6d89f7b85 1238 Gene3D G3DSA:3.20.20.80 743 1105 2.1E-62 T 29-03-2018 CDC59_RS17795 f5e847d72c657ee699489de6d89f7b85 1238 Pfam PF00128 Alpha amylase, catalytic domain 767 912 1.0E-4 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CDC59_RS17795 f5e847d72c657ee699489de6d89f7b85 1238 SUPERFAMILY SSF51445 738 1101 1.11E-87 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CDC59_RS17795 f5e847d72c657ee699489de6d89f7b85 1238 SMART SM00642 750 1080 9.4E-5 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CDC59_RS17795 f5e847d72c657ee699489de6d89f7b85 1238 Pfam PF11896 Domain of unknown function (DUF3416) 555 740 3.0E-57 T 29-03-2018 IPR021828 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase, domain N/S GO:0004553 KEGG: 00500+2.4.99.16 CDC59_RS17795 f5e847d72c657ee699489de6d89f7b85 1238 Gene3D G3DSA:2.60.40.1180 1106 1238 8.4E-25 T 29-03-2018 CDC59_RS17795 f5e847d72c657ee699489de6d89f7b85 1238 Hamap MF_02124 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase [glgE]. 552 1229 46.961 T 29-03-2018 IPR026585 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase GO:0016757 KEGG: 00500+2.4.99.16 CDC59_RS17795 f5e847d72c657ee699489de6d89f7b85 1238 Gene3D G3DSA:2.60.40.10 552 650 6.2E-33 T 29-03-2018 IPR013783 Immunoglobulin-like fold CDC59_RS13500 2b7b0be2d0aefbbea29cd2e76849791a 305 Gene3D G3DSA:1.10.10.10 1 83 1.6E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS13500 2b7b0be2d0aefbbea29cd2e76849791a 305 SUPERFAMILY SSF46785 1 86 7.07E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS13500 2b7b0be2d0aefbbea29cd2e76849791a 305 Gene3D G3DSA:3.40.190.10 91 175 2.0E-17 T 29-03-2018 CDC59_RS13500 2b7b0be2d0aefbbea29cd2e76849791a 305 Pfam PF03466 LysR substrate binding domain 87 294 3.0E-37 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS13500 2b7b0be2d0aefbbea29cd2e76849791a 305 Gene3D G3DSA:3.40.190.10 176 266 3.2E-17 T 29-03-2018 CDC59_RS13500 2b7b0be2d0aefbbea29cd2e76849791a 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.4E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS13500 2b7b0be2d0aefbbea29cd2e76849791a 305 SUPERFAMILY SSF53850 89 297 5.61E-40 T 29-03-2018 CDC59_RS09260 ea3c47c8fb5ebfe72e6c811e3641d81e 308 SUPERFAMILY SSF117892 52 186 1.1E-39 T 29-03-2018 IPR001107 Band 7 domain CDC59_RS09260 ea3c47c8fb5ebfe72e6c811e3641d81e 308 Pfam PF01145 SPFH domain / Band 7 family 25 195 3.2E-30 T 29-03-2018 IPR001107 Band 7 domain CDC59_RS09260 ea3c47c8fb5ebfe72e6c811e3641d81e 308 Pfam PF16200 C-terminal region of band_7 244 303 1.1E-25 T 29-03-2018 IPR032435 Band 7, C-terminal extension Reactome: R-HSA-8949664 CDC59_RS09260 ea3c47c8fb5ebfe72e6c811e3641d81e 308 SMART SM00244 21 179 3.7E-57 T 29-03-2018 IPR001107 Band 7 domain CDC59_RS09260 ea3c47c8fb5ebfe72e6c811e3641d81e 308 PRINTS PR00721 Stomatin signature 28 50 2.3E-31 T 29-03-2018 IPR001972 Stomatin family GO:0016020 CDC59_RS09260 ea3c47c8fb5ebfe72e6c811e3641d81e 308 PRINTS PR00721 Stomatin signature 174 195 2.3E-31 T 29-03-2018 IPR001972 Stomatin family GO:0016020 CDC59_RS09260 ea3c47c8fb5ebfe72e6c811e3641d81e 308 PRINTS PR00721 Stomatin signature 155 173 2.3E-31 T 29-03-2018 IPR001972 Stomatin family GO:0016020 CDC59_RS09260 ea3c47c8fb5ebfe72e6c811e3641d81e 308 PRINTS PR00721 Stomatin signature 131 154 2.3E-31 T 29-03-2018 IPR001972 Stomatin family GO:0016020 CDC59_RS09260 ea3c47c8fb5ebfe72e6c811e3641d81e 308 PRINTS PR00721 Stomatin signature 111 128 2.3E-31 T 29-03-2018 IPR001972 Stomatin family GO:0016020 CDC59_RS09260 ea3c47c8fb5ebfe72e6c811e3641d81e 308 PRINTS PR00721 Stomatin signature 76 97 2.3E-31 T 29-03-2018 IPR001972 Stomatin family GO:0016020 CDC59_RS00595 5386983f643f43000d2ca6a3659ab7c9 271 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 3 268 4.2E-105 T 29-03-2018 IPR010223 ATP binding protein MinD, bacterial-type GO:0016887 CDC59_RS00595 5386983f643f43000d2ca6a3659ab7c9 271 Gene3D G3DSA:3.40.50.300 1 258 2.3E-52 T 29-03-2018 CDC59_RS00595 5386983f643f43000d2ca6a3659ab7c9 271 PIRSF PIRSF003092 1 271 1.4E-90 T 29-03-2018 IPR025501 ATP binding protein MinD CDC59_RS00595 5386983f643f43000d2ca6a3659ab7c9 271 SUPERFAMILY SSF52540 1 269 2.28E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS00595 5386983f643f43000d2ca6a3659ab7c9 271 Pfam PF13614 AAA domain 2 159 1.5E-18 T 29-03-2018 IPR025669 AAA domain CDC59_RS00645 f295a0f854211e4b99941b59ef3d586d 76 Pfam PF12512 Protein of unknown function (DUF3717) 6 70 1.5E-30 T 29-03-2018 IPR022191 Protein of unknown function DUF3717 CDC59_RS04735 0c08dd838068a075e4f08bc531bcb2b7 144 TIGRFAM TIGR02801 tolR: protein TolR 14 141 1.2E-40 T 29-03-2018 IPR014168 Biopolymer transport, TolR GO:0015031|GO:0016021 CDC59_RS04735 0c08dd838068a075e4f08bc531bcb2b7 144 Pfam PF02472 Biopolymer transport protein ExbD/TolR 11 142 7.4E-27 T 29-03-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 CDC59_RS09390 63e4d773d65d657bca18e6fbbd4ae1d3 84 Pfam PF13560 Helix-turn-helix domain 10 64 6.6E-11 T 29-03-2018 CDC59_RS09390 63e4d773d65d657bca18e6fbbd4ae1d3 84 SUPERFAMILY SSF47413 9 69 7.88E-15 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDC59_RS09390 63e4d773d65d657bca18e6fbbd4ae1d3 84 SMART SM00530 14 69 1.9E-9 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDC59_RS09390 63e4d773d65d657bca18e6fbbd4ae1d3 84 Gene3D G3DSA:1.10.260.40 3 72 1.3E-12 T 29-03-2018 CDC59_RS15075 71fa816d8a5e4d5e15c1b6d25abf48f4 187 Pfam PF00583 Acetyltransferase (GNAT) family 71 155 1.5E-10 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CDC59_RS15075 71fa816d8a5e4d5e15c1b6d25abf48f4 187 SUPERFAMILY SSF55729 9 182 2.62E-26 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDC59_RS15075 71fa816d8a5e4d5e15c1b6d25abf48f4 187 Gene3D G3DSA:3.40.630.30 5 186 2.1E-30 T 29-03-2018 CDC59_RS09740 d10a5cfc2cc8bf19d956d42b77332fae 440 Gene3D G3DSA:3.40.710.10 127 440 7.5E-53 T 29-03-2018 CDC59_RS09740 d10a5cfc2cc8bf19d956d42b77332fae 440 SUPERFAMILY SSF56601 62 437 3.19E-96 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CDC59_RS09740 d10a5cfc2cc8bf19d956d42b77332fae 440 Pfam PF00144 Beta-lactamase 130 413 2.1E-41 T 29-03-2018 IPR001466 Beta-lactamase-related CDC59_RS15795 349e16095da2ebe6b941e90dc9dc32cc 129 SUPERFAMILY SSF52833 16 93 9.15E-16 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS15795 349e16095da2ebe6b941e90dc9dc32cc 129 Gene3D G3DSA:3.40.30.10 4 108 3.9E-13 T 29-03-2018 CDC59_RS15795 349e16095da2ebe6b941e90dc9dc32cc 129 Pfam PF00085 Thioredoxin 17 83 3.5E-10 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 CDC59_RS10665 eb1ee8d6f74ff6aa0060ff29f8812c46 376 SUPERFAMILY SSF56349 248 367 4.83E-9 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CDC59_RS10665 eb1ee8d6f74ff6aa0060ff29f8812c46 376 Pfam PF13102 Phage integrase SAM-like domain 268 339 1.6E-5 T 29-03-2018 IPR025269 Phage integrase SAM-like domain CDC59_RS10665 eb1ee8d6f74ff6aa0060ff29f8812c46 376 Gene3D G3DSA:1.10.150.130 240 345 4.0E-10 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal CDC59_RS17285 974131af24c630eba016517098ab18cc 224 Pfam PF07077 Protein of unknown function (DUF1345) 45 214 2.3E-60 T 29-03-2018 IPR009781 Protein of unknown function DUF1345 CDC59_RS02185 5f30f58512b6381f18e1892a7c813dbc 576 Pfam PF08486 Stage II sporulation protein 342 398 1.8E-5 T 29-03-2018 IPR013693 Sporulation stage II protein D, amidase enhancer LytB N-terminal CDC59_RS02185 5f30f58512b6381f18e1892a7c813dbc 576 Pfam PF10062 Predicted secreted protein (DUF2300) 434 555 3.5E-36 T 29-03-2018 IPR018748 Domain of unknown function DUF2300, secreted CDC59_RS02185 5f30f58512b6381f18e1892a7c813dbc 576 Pfam PF10062 Predicted secreted protein (DUF2300) 105 228 3.1E-33 T 29-03-2018 IPR018748 Domain of unknown function DUF2300, secreted CDC59_RS02185 5f30f58512b6381f18e1892a7c813dbc 576 SUPERFAMILY SSF56601 72 255 1.31E-5 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CDC59_RS01555 4383f518dac56f4eb7a1bda74eb95c25 457 Gene3D G3DSA:3.30.70.270 278 454 3.8E-53 T 29-03-2018 CDC59_RS01555 4383f518dac56f4eb7a1bda74eb95c25 457 SUPERFAMILY SSF55073 290 446 8.32E-46 T 29-03-2018 IPR029787 Nucleotide cyclase CDC59_RS01555 4383f518dac56f4eb7a1bda74eb95c25 457 SMART SM00267 274 448 5.1E-56 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS01555 4383f518dac56f4eb7a1bda74eb95c25 457 Pfam PF17158 Membrane-associated sensor, integral membrane domain 42 271 7.7E-36 T 29-03-2018 IPR033424 Membrane-associated sensor domain CDC59_RS01555 4383f518dac56f4eb7a1bda74eb95c25 457 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 281 446 1.6E-48 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS01555 4383f518dac56f4eb7a1bda74eb95c25 457 Pfam PF00990 Diguanylate cyclase, GGDEF domain 286 443 3.3E-46 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS01135 1bfd9e6b4bf1deac0ddb7c587eb26726 234 SUPERFAMILY SSF53098 34 217 5.12E-24 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDC59_RS01135 1bfd9e6b4bf1deac0ddb7c587eb26726 234 Gene3D G3DSA:3.30.420.10 37 229 7.9E-13 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDC59_RS07695 5b9203b8b4aae2215c8743598f3c5861 111 Pfam PF04977 Septum formation initiator 11 89 5.3E-26 T 29-03-2018 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 CDC59_RS07695 5b9203b8b4aae2215c8743598f3c5861 111 Hamap MF_00599 Cell division protein FtsB [ftsB]. 1 90 34.227 T 29-03-2018 IPR023081 Cell division protein FtsB CDC59_RS15500 e35d7bfa429c83c2b19d57c711675a52 657 Pfam PF01569 PAP2 superfamily 238 345 7.1E-12 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CDC59_RS15500 e35d7bfa429c83c2b19d57c711675a52 657 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 510 539 8.5E-10 T 29-03-2018 IPR013425 Autotransporter-associated beta strand repeat CDC59_RS15500 e35d7bfa429c83c2b19d57c711675a52 657 SUPERFAMILY SSF48317 229 362 2.22E-24 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CDC59_RS15500 e35d7bfa429c83c2b19d57c711675a52 657 SMART SM00014 231 347 0.001 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CDC59_RS15500 e35d7bfa429c83c2b19d57c711675a52 657 Gene3D G3DSA:1.20.144.10 133 369 7.0E-27 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CDC59_RS15500 e35d7bfa429c83c2b19d57c711675a52 657 Pfam PF12951 Passenger-associated-transport-repeat 510 538 4.6E-7 T 29-03-2018 IPR013425 Autotransporter-associated beta strand repeat CDC59_RS13650 9c8747d22d5f9b024ea6c44186cacea0 495 SUPERFAMILY SSF54534 236 339 1.9E-25 T 29-03-2018 CDC59_RS13650 9c8747d22d5f9b024ea6c44186cacea0 495 SUPERFAMILY SSF54534 350 449 5.63E-31 T 29-03-2018 CDC59_RS13650 9c8747d22d5f9b024ea6c44186cacea0 495 Gene3D G3DSA:1.10.4030.10 83 210 2.4E-21 T 29-03-2018 CDC59_RS13650 9c8747d22d5f9b024ea6c44186cacea0 495 Hamap MF_01183 Chaperone SurA [surA]. 27 492 32.317 T 29-03-2018 IPR023034 Peptidyl-prolyl isomerase SurA GO:0003755|GO:0006457|GO:0030288|GO:0042277|GO:0042710|GO:0043165|GO:0050821|GO:0051082|GO:0051085|GO:0060274 CDC59_RS13650 9c8747d22d5f9b024ea6c44186cacea0 495 Pfam PF09312 SurA N-terminal domain 87 204 1.6E-39 T 29-03-2018 IPR015391 SurA N-terminal CDC59_RS13650 9c8747d22d5f9b024ea6c44186cacea0 495 Gene3D G3DSA:3.10.50.40 348 482 4.4E-32 T 29-03-2018 CDC59_RS13650 9c8747d22d5f9b024ea6c44186cacea0 495 Gene3D G3DSA:3.10.50.40 229 347 1.2E-25 T 29-03-2018 CDC59_RS13650 9c8747d22d5f9b024ea6c44186cacea0 495 Pfam PF00639 PPIC-type PPIASE domain 242 335 6.2E-19 T 29-03-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 CDC59_RS13650 9c8747d22d5f9b024ea6c44186cacea0 495 Pfam PF13616 PPIC-type PPIASE domain 347 446 7.5E-25 T 29-03-2018 CDC59_RS13650 9c8747d22d5f9b024ea6c44186cacea0 495 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 386 406 - T 29-03-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 CDC59_RS13650 9c8747d22d5f9b024ea6c44186cacea0 495 SUPERFAMILY SSF109998 87 265 1.26E-41 T 29-03-2018 IPR027304 Trigger factor/SurA domain CDC59_RS06985 d1d226f8b531e1569f678da98053ec85 156 ProSitePatterns PS00801 Transketolase signature 1. 70 89 - T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CDC59_RS06985 d1d226f8b531e1569f678da98053ec85 156 SUPERFAMILY SSF55298 6 155 8.48E-50 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CDC59_RS06985 d1d226f8b531e1569f678da98053ec85 156 Gene3D G3DSA:3.30.1330.40 1 156 4.7E-27 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CDC59_RS06985 d1d226f8b531e1569f678da98053ec85 156 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 10 155 2.1E-26 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CDC59_RS09345 0fdff858925910dd2589e62e5de42d52 246 Pfam PF00775 Dioxygenase 50 231 1.5E-50 T 29-03-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 CDC59_RS09345 0fdff858925910dd2589e62e5de42d52 246 Pfam PF12391 Protocatechuate 3,4-dioxygenase beta subunit N terminal 13 42 1.7E-14 T 29-03-2018 IPR024756 Protocatechuate 3,4-dioxygenase beta subunit, N-terminal KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3 CDC59_RS09345 0fdff858925910dd2589e62e5de42d52 246 SUPERFAMILY SSF49482 12 241 1.3E-74 T 29-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CDC59_RS09345 0fdff858925910dd2589e62e5de42d52 246 ProSitePatterns PS00083 Intradiol ring-cleavage dioxygenases signature. 83 111 - T 29-03-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 CDC59_RS09345 0fdff858925910dd2589e62e5de42d52 246 Gene3D G3DSA:2.60.130.10 5 241 7.8E-58 T 29-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CDC59_RS09345 0fdff858925910dd2589e62e5de42d52 246 TIGRFAM TIGR02422 protocat_beta: protocatechuate 3,4-dioxygenase, beta subunit 19 240 3.5E-108 T 29-03-2018 IPR012785 Protocatechuate 3,4-dioxygenase, beta subunit GO:0005506|GO:0018578|GO:0019619|GO:0055114 KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3 CDC59_RS03425 08d0d92aa45166ea4ae294efc8aaa6e0 154 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 110 127 - T 29-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CDC59_RS03425 08d0d92aa45166ea4ae294efc8aaa6e0 154 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 83 96 1.5E-20 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CDC59_RS03425 08d0d92aa45166ea4ae294efc8aaa6e0 154 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 115 128 1.5E-20 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CDC59_RS03425 08d0d92aa45166ea4ae294efc8aaa6e0 154 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 100 114 1.5E-20 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CDC59_RS03425 08d0d92aa45166ea4ae294efc8aaa6e0 154 Pfam PF00364 Biotin-requiring enzyme 81 153 3.6E-26 T 29-03-2018 IPR000089 Biotin/lipoyl attachment CDC59_RS03425 08d0d92aa45166ea4ae294efc8aaa6e0 154 SUPERFAMILY SSF51230 79 153 8.25E-26 T 29-03-2018 IPR011053 Single hybrid motif CDC59_RS03425 08d0d92aa45166ea4ae294efc8aaa6e0 154 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 1 153 8.2E-58 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CDC59_RS03425 08d0d92aa45166ea4ae294efc8aaa6e0 154 Gene3D G3DSA:2.40.50.100 4 154 1.6E-21 T 29-03-2018 CDC59_RS19045 ecfac4d41c1de2e97ec3553881b09618 201 SUPERFAMILY SSF51182 10 194 4.59E-41 T 29-03-2018 IPR011051 RmlC-like cupin domain CDC59_RS19045 ecfac4d41c1de2e97ec3553881b09618 201 Gene3D G3DSA:2.60.120.10 2 200 7.4E-28 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CDC59_RS13815 34b3410e6353f902f46c9b0a146f2a5a 344 SUPERFAMILY SSF51556 3 342 1.32E-150 T 29-03-2018 IPR032466 Metal-dependent hydrolase CDC59_RS13815 34b3410e6353f902f46c9b0a146f2a5a 344 PIRSF PIRSF001237 1 344 6.1E-141 T 29-03-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDC59_RS13815 34b3410e6353f902f46c9b0a146f2a5a 344 TIGRFAM TIGR00856 pyrC_dimer: dihydroorotase, homodimeric type 5 342 7.9E-145 T 29-03-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDC59_RS13815 34b3410e6353f902f46c9b0a146f2a5a 344 ProSitePatterns PS00483 Dihydroorotase signature 2. 246 257 - T 29-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDC59_RS13815 34b3410e6353f902f46c9b0a146f2a5a 344 ProSitePatterns PS00482 Dihydroorotase signature 1. 12 20 - T 29-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDC59_RS13815 34b3410e6353f902f46c9b0a146f2a5a 344 Hamap MF_00219 Dihydroorotase [pyrC]. 3 344 44.687 T 29-03-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CDC59_RS13815 34b3410e6353f902f46c9b0a146f2a5a 344 Gene3D G3DSA:3.20.20.140 11 344 2.8E-57 T 29-03-2018 CDC59_RS13815 34b3410e6353f902f46c9b0a146f2a5a 344 Pfam PF01979 Amidohydrolase family 12 311 8.1E-22 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CDC59_RS20280 8a4c328f38945275145a1add8b5f14c6 171 Pfam PF04657 Putative inner membrane exporter, YdcZ 13 149 1.7E-36 T 29-03-2018 IPR006750 Putative inner membrane exporter, YdcZ CDC59_RS03965 84f6d863b85bc7c66f61214a4d9018de 185 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 28 178 2.0E-80 T 29-03-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 CDC59_RS03965 84f6d863b85bc7c66f61214a4d9018de 185 Gene3D G3DSA:1.20.1200.10 17 183 2.0E-62 T 29-03-2018 CDC59_RS03965 84f6d863b85bc7c66f61214a4d9018de 185 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 10 178 1.9E-65 T 29-03-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 CDC59_RS03965 84f6d863b85bc7c66f61214a4d9018de 185 Pfam PF01923 Cobalamin adenosyltransferase 8 165 2.2E-56 T 29-03-2018 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 CDC59_RS03965 84f6d863b85bc7c66f61214a4d9018de 185 SUPERFAMILY SSF89028 7 178 2.35E-61 T 29-03-2018 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 CDC59_RS19905 e4539306659ff85da37f7c56e9aa45a3 339 Gene3D G3DSA:3.40.190.10 150 331 2.0E-26 T 29-03-2018 CDC59_RS19905 e4539306659ff85da37f7c56e9aa45a3 339 Pfam PF13343 Bacterial extracellular solute-binding protein 74 299 2.2E-30 T 29-03-2018 CDC59_RS19905 e4539306659ff85da37f7c56e9aa45a3 339 SUPERFAMILY SSF53850 22 330 1.7E-73 T 29-03-2018 CDC59_RS19905 e4539306659ff85da37f7c56e9aa45a3 339 PIRSF PIRSF002825 1 333 1.3E-93 T 29-03-2018 IPR026045 Ferric binding protein CDC59_RS19905 e4539306659ff85da37f7c56e9aa45a3 339 TIGRFAM TIGR03261 phnS2: putative 2-aminoethylphosphonate ABC transporter, periplasmic 2-aminoethylphosphonate-binding protein 11 337 6.6E-165 T 29-03-2018 IPR017663 ABC transport system, 1-aminoethylphosphonate-binding protein, putative CDC59_RS19905 e4539306659ff85da37f7c56e9aa45a3 339 Gene3D G3DSA:3.40.190.10 24 149 1.1E-16 T 29-03-2018 CDC59_RS01425 4046c6db90e9094b5297e4fb4db8dbc8 484 TIGRFAM TIGR00797 matE: MATE efflux family protein 29 431 4.1E-66 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CDC59_RS01425 4046c6db90e9094b5297e4fb4db8dbc8 484 PIRSF PIRSF006603 5 460 1.4E-104 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CDC59_RS01425 4046c6db90e9094b5297e4fb4db8dbc8 484 Pfam PF01554 MatE 258 418 7.3E-23 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CDC59_RS01425 4046c6db90e9094b5297e4fb4db8dbc8 484 Pfam PF01554 MatE 29 190 3.2E-28 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CDC59_RS00465 e49f7cc158487e28abcf14a3501a0d3f 952 SMART SM00487 163 347 3.2E-5 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CDC59_RS00465 e49f7cc158487e28abcf14a3501a0d3f 952 SUPERFAMILY SSF52540 118 357 1.19E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS00465 e49f7cc158487e28abcf14a3501a0d3f 952 Pfam PF08463 EcoEI R protein C-terminal 798 944 8.7E-13 T 29-03-2018 IPR013670 EcoEI R protein C-terminal domain GO:0003677|GO:0003824|GO:0006304 CDC59_RS00465 e49f7cc158487e28abcf14a3501a0d3f 952 Gene3D G3DSA:3.40.50.300 137 336 1.0E-19 T 29-03-2018 CDC59_RS00465 e49f7cc158487e28abcf14a3501a0d3f 952 Pfam PF04851 Type III restriction enzyme, res subunit 167 320 2.2E-23 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CDC59_RS17115 95010d51b47d6283e602d970b55b464d 165 Pfam PF03748 Flagellar basal body-associated protein FliL 64 165 5.5E-25 T 29-03-2018 IPR005503 Flagellar basal body-associated protein FliL GO:0006935|GO:0009425|GO:0071973 CDC59_RS17115 95010d51b47d6283e602d970b55b464d 165 Gene3D G3DSA:1.20.1000.10 84 165 6.8E-4 T 29-03-2018 CDC59_RS11200 75ad1aff09aeec6fd5685b05a8aabc54 197 Pfam PF02627 Carboxymuconolactone decarboxylase family 57 135 6.7E-13 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CDC59_RS11200 75ad1aff09aeec6fd5685b05a8aabc54 197 TIGRFAM TIGR01926 peroxid_rel: uncharacterized peroxidase-related enzyme 19 193 4.2E-71 T 29-03-2018 IPR010195 Uncharacterised peroxidase-related CDC59_RS11200 75ad1aff09aeec6fd5685b05a8aabc54 197 Gene3D G3DSA:1.20.1290.10 34 195 6.5E-31 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CDC59_RS11200 75ad1aff09aeec6fd5685b05a8aabc54 197 SUPERFAMILY SSF69118 13 191 2.37E-46 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CDC59_RS11200 75ad1aff09aeec6fd5685b05a8aabc54 197 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 75 104 2.5E-9 T 29-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CDC59_RS05105 177dec7f2c6ddb94d371eecfb7c5970c 345 PIRSF PIRSF038940 1 344 2.9E-162 T 29-03-2018 IPR026273 Low specificity L-threonine aldolase GO:0004793|GO:0006567 KEGG: 00260+4.1.2.48 CDC59_RS05105 177dec7f2c6ddb94d371eecfb7c5970c 345 Gene3D G3DSA:3.90.1150.10 248 345 1.1E-20 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS05105 177dec7f2c6ddb94d371eecfb7c5970c 345 SUPERFAMILY SSF53383 1 337 1.38E-101 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS05105 177dec7f2c6ddb94d371eecfb7c5970c 345 Gene3D G3DSA:3.40.640.10 13 247 1.9E-34 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDC59_RS05105 177dec7f2c6ddb94d371eecfb7c5970c 345 Pfam PF01212 Beta-eliminating lyase 4 292 2.9E-79 T 29-03-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 CDC59_RS23875 0408e8b6abe5ac919384b9841d4c4a76 125 Pfam PF13473 Cupredoxin-like domain 19 124 1.0E-13 T 29-03-2018 IPR028096 EfeO-type cupredoxin-like domain CDC59_RS23875 0408e8b6abe5ac919384b9841d4c4a76 125 Gene3D G3DSA:2.60.40.420 18 125 1.2E-21 T 29-03-2018 IPR008972 Cupredoxin CDC59_RS23875 0408e8b6abe5ac919384b9841d4c4a76 125 SUPERFAMILY SSF49503 27 124 2.67E-26 T 29-03-2018 IPR008972 Cupredoxin CDC59_RS22630 015e536235b4f84cb54b056978b58378 421 Gene3D G3DSA:2.120.10.10 150 406 9.8E-21 T 29-03-2018 CDC59_RS22630 015e536235b4f84cb54b056978b58378 421 Gene3D G3DSA:2.120.10.10 108 149 7.7E-8 T 29-03-2018 CDC59_RS22630 015e536235b4f84cb54b056978b58378 421 Gene3D G3DSA:2.120.10.10 29 107 4.6E-6 T 29-03-2018 CDC59_RS22630 015e536235b4f84cb54b056978b58378 421 SUPERFAMILY SSF50939 268 390 3.14E-7 T 29-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 CDC59_RS22630 015e536235b4f84cb54b056978b58378 421 SUPERFAMILY SSF50939 51 310 1.65E-24 T 29-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 CDC59_RS14995 9fbfc1ccdf8a9eec3346a0844aaa8992 360 Hamap MF_01694 Biotin synthase [bioB]. 25 333 42.417 T 29-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CDC59_RS14995 9fbfc1ccdf8a9eec3346a0844aaa8992 360 SMART SM00729 63 275 5.1E-37 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CDC59_RS14995 9fbfc1ccdf8a9eec3346a0844aaa8992 360 TIGRFAM TIGR00433 bioB: biotin synthase 35 330 3.0E-124 T 29-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CDC59_RS14995 9fbfc1ccdf8a9eec3346a0844aaa8992 360 SMART SM00876 240 332 1.4E-48 T 29-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CDC59_RS14995 9fbfc1ccdf8a9eec3346a0844aaa8992 360 PIRSF PIRSF001619 18 339 6.2E-134 T 29-03-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CDC59_RS14995 9fbfc1ccdf8a9eec3346a0844aaa8992 360 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 240 330 1.4E-20 T 29-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CDC59_RS14995 9fbfc1ccdf8a9eec3346a0844aaa8992 360 Gene3D G3DSA:3.20.20.70 24 335 1.1E-58 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS14995 9fbfc1ccdf8a9eec3346a0844aaa8992 360 Pfam PF04055 Radical SAM superfamily 70 222 3.7E-15 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CDC59_RS14995 9fbfc1ccdf8a9eec3346a0844aaa8992 360 SUPERFAMILY SSF102114 25 331 6.93E-91 T 29-03-2018 CDC59_RS18535 b69a88e2fa1b0e235db4366cadcac138 140 Pfam PF07007 Lysozyme inhibitor LprI 43 135 4.7E-14 T 29-03-2018 IPR009739 Lysozyme inhibitor LprI, N-terminal CDC59_RS22750 05af7a0db84bd42cdc99c434241482b3 736 Pfam PF05819 NolX protein 109 203 2.0E-8 T 29-03-2018 IPR008718 NolX GO:0009877 CDC59_RS22750 05af7a0db84bd42cdc99c434241482b3 736 Pfam PF05819 NolX protein 289 584 1.0E-82 T 29-03-2018 IPR008718 NolX GO:0009877 CDC59_RS22750 05af7a0db84bd42cdc99c434241482b3 736 Pfam PF05819 NolX protein 204 293 5.1E-34 T 29-03-2018 IPR008718 NolX GO:0009877 CDC59_RS21715 e1deadfd80d37c16160b5a1608a6d6bc 175 Pfam PF07813 LTXXQ motif family protein 56 155 5.6E-18 T 29-03-2018 IPR012899 LTXXQ motif family protein GO:0042597 CDC59_RS01605 aad3c2e737f1277c94b684d3b73c8209 182 Pfam PF13420 Acetyltransferase (GNAT) domain 21 166 5.0E-16 T 29-03-2018 CDC59_RS01605 aad3c2e737f1277c94b684d3b73c8209 182 SUPERFAMILY SSF55729 18 174 1.11E-30 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDC59_RS01605 aad3c2e737f1277c94b684d3b73c8209 182 Gene3D G3DSA:3.40.630.30 13 180 2.0E-32 T 29-03-2018 CDC59_RS12400 96d97e089721cd37c93d44a72e86391f 557 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 556 5.6E-225 T 29-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CDC59_RS12400 96d97e089721cd37c93d44a72e86391f 557 SUPERFAMILY SSF143975 4 378 7.32E-133 T 29-03-2018 CDC59_RS12400 96d97e089721cd37c93d44a72e86391f 557 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 465 476 - T 29-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CDC59_RS12400 96d97e089721cd37c93d44a72e86391f 557 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 5 557 43.645 T 29-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CDC59_RS12400 96d97e089721cd37c93d44a72e86391f 557 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 123 133 - T 29-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CDC59_RS12400 96d97e089721cd37c93d44a72e86391f 557 Pfam PF00920 Dehydratase family 36 554 1.0E-203 T 29-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CDC59_RS12400 96d97e089721cd37c93d44a72e86391f 557 SUPERFAMILY SSF52016 380 556 6.36E-57 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CDC59_RS16630 6ff01f2c701cc9282630a615fd727aa8 260 SUPERFAMILY SSF48403 82 246 1.52E-29 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CDC59_RS16630 6ff01f2c701cc9282630a615fd727aa8 260 SMART SM00248 85 114 1.1 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CDC59_RS16630 6ff01f2c701cc9282630a615fd727aa8 260 SMART SM00248 222 254 2300.0 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CDC59_RS16630 6ff01f2c701cc9282630a615fd727aa8 260 SMART SM00248 189 218 1.2E-4 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CDC59_RS16630 6ff01f2c701cc9282630a615fd727aa8 260 Pfam PF12796 Ankyrin repeats (3 copies) 161 246 5.2E-10 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CDC59_RS16630 6ff01f2c701cc9282630a615fd727aa8 260 Pfam PF00023 Ankyrin repeat 86 116 0.015 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CDC59_RS16630 6ff01f2c701cc9282630a615fd727aa8 260 Gene3D G3DSA:1.25.40.20 139 254 1.8E-20 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CDC59_RS16630 6ff01f2c701cc9282630a615fd727aa8 260 Gene3D G3DSA:1.25.40.20 48 138 8.9E-13 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CDC59_RS10545 1e91d8747bf9f251c96288f7e608dab3 95 Pfam PF07369 Protein of unknown function (DUF1488) 3 74 1.1E-14 T 29-03-2018 IPR009962 Protein of unknown function DUF1488 CDC59_RS10545 1e91d8747bf9f251c96288f7e608dab3 95 SUPERFAMILY SSF160272 1 73 1.01E-11 T 29-03-2018 IPR009962 Protein of unknown function DUF1488 CDC59_RS10545 1e91d8747bf9f251c96288f7e608dab3 95 Gene3D G3DSA:3.30.160.140 3 77 3.6E-12 T 29-03-2018 IPR009962 Protein of unknown function DUF1488 CDC59_RS13665 c36c50bd4a8fde871c2df5ae880f186a 242 Pfam PF03591 AzlC protein 18 163 8.4E-43 T 29-03-2018 IPR011606 Branched-chain amino acid transport, permease CDC59_RS23375 dabcb622529e0380ab0c17e847aec531 416 SUPERFAMILY SSF52096 58 174 2.49E-25 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CDC59_RS23375 dabcb622529e0380ab0c17e847aec531 416 SUPERFAMILY SSF52096 205 265 2.49E-25 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CDC59_RS23375 dabcb622529e0380ab0c17e847aec531 416 Gene3D G3DSA:3.90.226.10 65 264 3.9E-21 T 29-03-2018 CDC59_RS23375 dabcb622529e0380ab0c17e847aec531 416 Pfam PF01343 Peptidase family S49 128 271 3.5E-31 T 29-03-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 CDC59_RS16855 f5212d5abbe65e055ee10f20693a2b6b 385 Gene3D G3DSA:2.40.50.100 167 356 4.0E-6 T 29-03-2018 CDC59_RS16855 f5212d5abbe65e055ee10f20693a2b6b 385 Gene3D G3DSA:2.40.50.100 61 118 1.2E-16 T 29-03-2018 CDC59_RS16855 f5212d5abbe65e055ee10f20693a2b6b 385 Gene3D G3DSA:1.10.287.470 119 166 1.3E-10 T 29-03-2018 CDC59_RS16855 f5212d5abbe65e055ee10f20693a2b6b 385 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 60 289 9.4E-14 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CDC59_RS16855 f5212d5abbe65e055ee10f20693a2b6b 385 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 37 370 1.5E-79 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 CDC59_RS16855 f5212d5abbe65e055ee10f20693a2b6b 385 SUPERFAMILY SSF111369 49 294 2.88E-69 T 29-03-2018 CDC59_RS09215 32676aa441a47286f0eacd34f18ef152 390 TIGRFAM TIGR00215 lpxB: lipid-A-disaccharide synthase 12 382 4.2E-95 T 29-03-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 CDC59_RS09215 32676aa441a47286f0eacd34f18ef152 390 Pfam PF02684 Lipid-A-disaccharide synthetase 14 374 2.7E-95 T 29-03-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 CDC59_RS09215 32676aa441a47286f0eacd34f18ef152 390 Gene3D G3DSA:3.40.50.2000 30 188 5.2E-6 T 29-03-2018 CDC59_RS09215 32676aa441a47286f0eacd34f18ef152 390 Hamap MF_00392 Lipid-A-disaccharide synthase [lpxB]. 9 385 36.525 T 29-03-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 CDC59_RS09215 32676aa441a47286f0eacd34f18ef152 390 SUPERFAMILY SSF53756 10 352 4.71E-30 T 29-03-2018 CDC59_RS09215 32676aa441a47286f0eacd34f18ef152 390 Gene3D G3DSA:3.40.50.2000 189 378 5.6E-16 T 29-03-2018 CDC59_RS10730 1c7cdba312d8f9c36fbb101d980bb921 289 PRINTS PR00111 Alpha/beta hydrolase fold signature 58 73 9.3E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS10730 1c7cdba312d8f9c36fbb101d980bb921 289 PRINTS PR00111 Alpha/beta hydrolase fold signature 233 247 9.3E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS10730 1c7cdba312d8f9c36fbb101d980bb921 289 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 9.3E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS10730 1c7cdba312d8f9c36fbb101d980bb921 289 Pfam PF12697 Alpha/beta hydrolase family 35 279 8.9E-17 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS10730 1c7cdba312d8f9c36fbb101d980bb921 289 Gene3D G3DSA:3.40.50.1820 13 286 3.5E-44 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS10730 1c7cdba312d8f9c36fbb101d980bb921 289 SUPERFAMILY SSF53474 19 279 1.16E-42 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS20310 7260b4762c09aaebfa9a9b0857feaded 789 Pfam PF07715 TonB-dependent Receptor Plug Domain 175 269 1.3E-5 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CDC59_RS20310 7260b4762c09aaebfa9a9b0857feaded 789 Gene3D G3DSA:2.40.170.20 282 789 1.6E-41 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CDC59_RS20310 7260b4762c09aaebfa9a9b0857feaded 789 SUPERFAMILY SSF56935 164 789 3.66E-74 T 29-03-2018 CDC59_RS20310 7260b4762c09aaebfa9a9b0857feaded 789 Pfam PF00593 TonB dependent receptor 361 786 3.4E-34 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CDC59_RS20310 7260b4762c09aaebfa9a9b0857feaded 789 SMART SM00965 83 134 0.0071 T 29-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 CDC59_RS20310 7260b4762c09aaebfa9a9b0857feaded 789 Gene3D G3DSA:2.170.130.10 141 276 3.4E-10 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CDC59_RS22080 6d5398c75886db99998229f1657aacdc 347 Pfam PF16670 Phosphoinositide phospholipase C, Ca2+-dependent 108 249 3.5E-11 T 29-03-2018 IPR032075 Phosphoinositide phospholipase C, Ca2+-dependent CDC59_RS22080 6d5398c75886db99998229f1657aacdc 347 Gene3D G3DSA:3.20.20.190 29 302 1.6E-15 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CDC59_RS22080 6d5398c75886db99998229f1657aacdc 347 SUPERFAMILY SSF51695 193 216 7.85E-13 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CDC59_RS22080 6d5398c75886db99998229f1657aacdc 347 SUPERFAMILY SSF51695 38 158 7.85E-13 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CDC59_RS01495 44445b43ebf5b0d6dbbd591e476ea6df 369 SUPERFAMILY SSF140959 259 346 9.42E-71 T 29-03-2018 CDC59_RS01495 44445b43ebf5b0d6dbbd591e476ea6df 369 SUPERFAMILY SSF140959 5 199 9.42E-71 T 29-03-2018 CDC59_RS01495 44445b43ebf5b0d6dbbd591e476ea6df 369 Pfam PF03301 Tryptophan 2,3-dioxygenase 4 346 4.8E-67 T 29-03-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 CDC59_RS01495 44445b43ebf5b0d6dbbd591e476ea6df 369 Hamap MF_01972 Tryptophan 2,3-dioxygenase [kynA]. 2 346 34.682 T 29-03-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 CDC59_RS20665 2152763a0db20c040b4039dc849e81f2 353 Gene3D G3DSA:2.40.160.60 35 173 1.5E-4 T 29-03-2018 CDC59_RS05680 1ae341dc666e92f2a57d639db14e3d01 69 Gene3D G3DSA:1.10.1660.10 2 40 8.4E-4 T 29-03-2018 CDC59_RS16945 bbac36c097bcb1024ffa4efa7fe39b20 277 SUPERFAMILY SSF102198 2 260 2.49E-57 T 29-03-2018 CDC59_RS16945 bbac36c097bcb1024ffa4efa7fe39b20 277 Gene3D G3DSA:3.50.30.50 1 263 1.2E-54 T 29-03-2018 CDC59_RS16945 bbac36c097bcb1024ffa4efa7fe39b20 277 Pfam PF04199 Putative cyclase 6 190 1.4E-35 T 29-03-2018 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 CDC59_RS01885 08f34ee10d563385d732708ba15ad473 551 Gene3D G3DSA:3.50.50.60 44 199 8.0E-39 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS01885 08f34ee10d563385d732708ba15ad473 551 Gene3D G3DSA:3.50.50.60 200 527 1.5E-61 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS01885 08f34ee10d563385d732708ba15ad473 551 SUPERFAMILY SSF51905 331 448 6.26E-59 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS01885 08f34ee10d563385d732708ba15ad473 551 SUPERFAMILY SSF51905 44 264 6.26E-59 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS01885 08f34ee10d563385d732708ba15ad473 551 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 47 243 3.9E-16 T 29-03-2018 CDC59_RS12290 3fe752840da68c6c9a5421b93f14c271 62 Pfam PF11943 Protein of unknown function (DUF3460) 4 60 1.5E-28 T 29-03-2018 IPR021853 Protein of unknown function DUF3460 CDC59_RS01980 b3fd9f3cc9496aef2d83e99fa76db0c7 388 Pfam PF13458 Periplasmic binding protein 44 373 2.0E-57 T 29-03-2018 IPR028081 Leucine-binding protein domain CDC59_RS01980 b3fd9f3cc9496aef2d83e99fa76db0c7 388 Gene3D G3DSA:3.40.50.2300 208 376 2.3E-25 T 29-03-2018 CDC59_RS01980 b3fd9f3cc9496aef2d83e99fa76db0c7 388 SUPERFAMILY SSF53822 43 387 2.33E-65 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CDC59_RS01980 b3fd9f3cc9496aef2d83e99fa76db0c7 388 Gene3D G3DSA:3.40.50.2300 35 207 3.5E-22 T 29-03-2018 CDC59_RS08810 cc58968612fd37a3ee97428f0f9bd80a 340 TIGRFAM TIGR00971 3a0106s03: sulfate ABC transporter, sulfate-binding protein 28 334 2.5E-153 T 29-03-2018 IPR005669 Thiosulphate/Sulfate-binding protein GO:0008272|GO:0015419 CDC59_RS08810 cc58968612fd37a3ee97428f0f9bd80a 340 Gene3D G3DSA:3.40.190.10 28 133 2.1E-27 T 29-03-2018 CDC59_RS08810 cc58968612fd37a3ee97428f0f9bd80a 340 Pfam PF13531 Bacterial extracellular solute-binding protein 39 288 1.2E-46 T 29-03-2018 CDC59_RS08810 cc58968612fd37a3ee97428f0f9bd80a 340 ProSitePatterns PS00757 Prokaryotic sulfate-binding proteins signature 2. 153 161 - T 29-03-2018 IPR034408 Sulphate/thiosulphate-binding site GO:1901681 CDC59_RS08810 cc58968612fd37a3ee97428f0f9bd80a 340 Gene3D G3DSA:3.40.190.10 134 337 7.5E-49 T 29-03-2018 CDC59_RS08810 cc58968612fd37a3ee97428f0f9bd80a 340 SUPERFAMILY SSF53850 28 336 2.57E-92 T 29-03-2018 CDC59_RS04090 5352542c17bb0872e297f5280668aa19 140 Gene3D G3DSA:3.40.30.10 15 55 0.092 T 29-03-2018 CDC59_RS04090 5352542c17bb0872e297f5280668aa19 140 Pfam PF00085 Thioredoxin 37 127 9.0E-5 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 CDC59_RS04090 5352542c17bb0872e297f5280668aa19 140 Gene3D G3DSA:3.40.30.10 56 131 8.1E-9 T 29-03-2018 CDC59_RS04090 5352542c17bb0872e297f5280668aa19 140 SUPERFAMILY SSF52833 15 134 1.93E-22 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS08425 5f30384c86090c617529465843580335 108 Gene3D G3DSA:1.20.120.330 2 108 1.4E-5 T 29-03-2018 CDC59_RS18755 7c4e9112e74b43d8033795e865b0f563 87 Pfam PF05488 PAAR motif 7 79 1.4E-24 T 29-03-2018 IPR008727 PAAR motif CDC59_RS05045 f87ef6a764f077febef195a0d54ff1e7 109 Pfam PF01863 Protein of unknown function DUF45 4 99 8.0E-35 T 29-03-2018 IPR002725 Protein of unknown function DUF45 CDC59_RS16390 ecf0653ca9d08155fdc39eb76d0bd670 103 Gene3D G3DSA:1.10.260.40 34 101 1.4E-12 T 29-03-2018 CDC59_RS16390 ecf0653ca9d08155fdc39eb76d0bd670 103 SUPERFAMILY SSF47413 42 90 1.58E-9 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDC59_RS09785 3f16595fea95c515be8e464d8f4ee345 151 SUPERFAMILY SSF55729 15 149 9.22E-43 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDC59_RS09785 3f16595fea95c515be8e464d8f4ee345 151 Gene3D G3DSA:3.40.630.30 11 151 2.8E-38 T 29-03-2018 CDC59_RS09785 3f16595fea95c515be8e464d8f4ee345 151 Pfam PF13673 Acetyltransferase (GNAT) domain 52 150 2.6E-20 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CDC59_RS18710 e3f5b11b25d65bd1eebd42e038b4261d 249 Pfam PF05433 Glycine zipper 2TM domain 161 201 2.8E-9 T 29-03-2018 IPR008816 Glycine zipper 2TM domain GO:0019867 CDC59_RS17840 b6c03376c5db24df2e1567f0e7c896ce 151 SUPERFAMILY SSF46785 7 135 5.66E-39 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS17840 b6c03376c5db24df2e1567f0e7c896ce 151 Gene3D G3DSA:1.10.10.10 3 91 1.3E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS17840 b6c03376c5db24df2e1567f0e7c896ce 151 Pfam PF01475 Ferric uptake regulator family 10 131 2.8E-40 T 29-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CDC59_RS11580 c0fe1ee67047875502a251374ddd22ea 244 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 12 209 9.1E-35 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CDC59_RS11580 c0fe1ee67047875502a251374ddd22ea 244 SMART SM00855 11 172 4.6E-13 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CDC59_RS11580 c0fe1ee67047875502a251374ddd22ea 244 SUPERFAMILY SSF53254 10 213 5.24E-36 T 29-03-2018 IPR029033 Histidine phosphatase superfamily CDC59_RS11580 c0fe1ee67047875502a251374ddd22ea 244 PIRSF PIRSF000709 6 176 1.3E-4 T 29-03-2018 CDC59_RS11580 c0fe1ee67047875502a251374ddd22ea 244 Gene3D G3DSA:3.40.50.1240 9 214 1.2E-31 T 29-03-2018 IPR029033 Histidine phosphatase superfamily CDC59_RS06900 910688cf250b5105ab90e5a05c589fae 321 Pfam PF11004 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase 45 315 3.5E-112 T 29-03-2018 IPR021266 Kdo hydroxylase CDC59_RS07185 d34dacf39810c4b38b020894eebf2eaf 252 Pfam PF05433 Glycine zipper 2TM domain 165 203 3.1E-8 T 29-03-2018 IPR008816 Glycine zipper 2TM domain GO:0019867 CDC59_RS02000 221bd1112f7e7d51ae879b42da969552 535 Gene3D G3DSA:2.60.40.10 423 531 4.5E-29 T 29-03-2018 IPR013783 Immunoglobulin-like fold CDC59_RS02000 221bd1112f7e7d51ae879b42da969552 535 SUPERFAMILY SSF81296 422 530 2.24E-30 T 29-03-2018 IPR014756 Immunoglobulin E-set CDC59_RS02000 221bd1112f7e7d51ae879b42da969552 535 PIRSF PIRSF006281 1 531 9.3E-208 T 29-03-2018 IPR014438 Glucan biosynthesis, periplasmic, MdoG/D CDC59_RS02000 221bd1112f7e7d51ae879b42da969552 535 Pfam PF04349 Periplasmic glucan biosynthesis protein, MdoG 39 527 9.2E-197 T 29-03-2018 IPR007444 Glucan biosynthesis, periplasmic, MdoG C-terminal GO:0016051|GO:0042597 CDC59_RS02000 221bd1112f7e7d51ae879b42da969552 535 SUPERFAMILY SSF74650 39 421 4.39E-151 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CDC59_RS02000 221bd1112f7e7d51ae879b42da969552 535 Hamap MF_01068 Glucans biosynthesis protein D [mdoD]. 1 535 59.89 T 29-03-2018 IPR023724 Glucan biosynthesis, MdoD CDC59_RS02000 221bd1112f7e7d51ae879b42da969552 535 Gene3D G3DSA:2.70.98.10 39 419 1.2E-162 T 29-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CDC59_RS11280 11763a0f1f2f55e4cb9a334cb1930e33 319 Pfam PF00892 EamA-like transporter family 5 135 5.8E-20 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CDC59_RS11280 11763a0f1f2f55e4cb9a334cb1930e33 319 Pfam PF00892 EamA-like transporter family 155 291 2.0E-17 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CDC59_RS11280 11763a0f1f2f55e4cb9a334cb1930e33 319 SUPERFAMILY SSF103481 192 295 7.98E-12 T 29-03-2018 CDC59_RS11280 11763a0f1f2f55e4cb9a334cb1930e33 319 SUPERFAMILY SSF103481 37 137 2.75E-17 T 29-03-2018 CDC59_RS03985 6273fa6a6d8a308638a6f99edfa36342 486 Gene3D G3DSA:3.30.2290.10 25 240 5.0E-55 T 29-03-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal domain CDC59_RS03985 6273fa6a6d8a308638a6f99edfa36342 486 Pfam PF01523 Putative modulator of DNA gyrase 43 337 2.3E-70 T 29-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 CDC59_RS03985 6273fa6a6d8a308638a6f99edfa36342 486 SUPERFAMILY SSF111283 27 485 7.98E-134 T 29-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 CDC59_RS03985 6273fa6a6d8a308638a6f99edfa36342 486 PIRSF PIRSF004919 23 486 9.5E-140 T 29-03-2018 IPR025502 TldD CDC59_RS04490 2fee5ea8ae57d11f80c4f046ddaad991 309 SUPERFAMILY SSF53448 19 232 1.45E-24 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDC59_RS04490 2fee5ea8ae57d11f80c4f046ddaad991 309 Pfam PF00535 Glycosyl transferase family 2 20 160 6.1E-7 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CDC59_RS04490 2fee5ea8ae57d11f80c4f046ddaad991 309 Gene3D G3DSA:3.90.550.10 10 230 1.0E-18 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDC59_RS21655 bd8456ab42d0c6b69ca274d4219ca9c2 304 Hamap MF_00313 Glutaminase [glsA]. 3 304 46.531 T 29-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 CDC59_RS21655 bd8456ab42d0c6b69ca274d4219ca9c2 304 Gene3D G3DSA:3.40.710.10 1 304 6.0E-123 T 29-03-2018 CDC59_RS21655 bd8456ab42d0c6b69ca274d4219ca9c2 304 Pfam PF04960 Glutaminase 21 304 1.6E-109 T 29-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 CDC59_RS21655 bd8456ab42d0c6b69ca274d4219ca9c2 304 SUPERFAMILY SSF56601 2 304 1.48E-113 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CDC59_RS21655 bd8456ab42d0c6b69ca274d4219ca9c2 304 TIGRFAM TIGR03814 Gln_ase: glutaminase A 7 304 2.6E-123 T 29-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 CDC59_RS07565 b878588ef132a36992caa1c26a0bb164 303 SUPERFAMILY SSF109604 35 127 1.51E-12 T 29-03-2018 CDC59_RS07565 b878588ef132a36992caa1c26a0bb164 303 Gene3D G3DSA:1.10.3210.10 17 172 3.3E-14 T 29-03-2018 CDC59_RS07565 b878588ef132a36992caa1c26a0bb164 303 Pfam PF01966 HD domain 77 130 1.1E-4 T 29-03-2018 IPR006674 HD domain CDC59_RS18370 01ca3f7c62ac7c334bf37502c705d72a 299 Gene3D G3DSA:3.40.1130.10 45 228 2.3E-20 T 29-03-2018 CDC59_RS18370 01ca3f7c62ac7c334bf37502c705d72a 299 SMART SM00563 88 230 2.1E-18 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CDC59_RS18370 01ca3f7c62ac7c334bf37502c705d72a 299 Pfam PF01553 Acyltransferase 82 229 6.7E-13 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CDC59_RS18370 01ca3f7c62ac7c334bf37502c705d72a 299 SUPERFAMILY SSF69593 14 290 3.27E-34 T 29-03-2018 CDC59_RS20485 e71d87834ab0dc934596ee0f8ed10e66 244 Pfam PF00005 ABC transporter 17 167 1.7E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS20485 e71d87834ab0dc934596ee0f8ed10e66 244 PIRSF PIRSF039085 1 243 2.2E-108 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CDC59_RS20485 e71d87834ab0dc934596ee0f8ed10e66 244 SUPERFAMILY SSF52540 1 237 1.77E-81 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS20485 e71d87834ab0dc934596ee0f8ed10e66 244 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS20485 e71d87834ab0dc934596ee0f8ed10e66 244 SMART SM00382 26 215 4.1E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS20485 e71d87834ab0dc934596ee0f8ed10e66 244 Gene3D G3DSA:3.40.50.300 1 243 1.7E-73 T 29-03-2018 CDC59_RS05660 73bbb6a9ba5ce7ad591643bd7cd9a702 109 Pfam PF10734 Protein of unknown function (DUF2523) 63 100 1.4E-5 T 29-03-2018 IPR019670 Protein of unkown function DUF2523 CDC59_RS04825 8cb49b1710a8e94f18985e5aa3b2d461 176 Pfam PF11780 Protein of unknown function (DUF3318) 31 169 2.9E-29 T 29-03-2018 IPR021751 Protein of unknown function DUF3318 CDC59_RS18410 972845705148a4078f2fe0fcb05f2962 689 Gene3D G3DSA:1.20.910.10 42 273 0.39 T 29-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CDC59_RS18410 972845705148a4078f2fe0fcb05f2962 689 SMART SM01236 516 625 9.0E-29 T 29-03-2018 CDC59_RS18410 972845705148a4078f2fe0fcb05f2962 689 Gene3D G3DSA:1.20.910.10 448 671 2.0E-21 T 29-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CDC59_RS18410 972845705148a4078f2fe0fcb05f2962 689 Pfam PF14518 Iron-containing redox enzyme 487 667 4.3E-22 T 29-03-2018 IPR028201 PqqC-like protein CDC59_RS12675 f40b501c86c3e74425fe029f48e34154 108 SUPERFAMILY SSF54736 24 107 2.2E-32 T 29-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CDC59_RS12675 f40b501c86c3e74425fe029f48e34154 108 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 25 103 1.2E-34 T 29-03-2018 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 CDC59_RS12675 f40b501c86c3e74425fe029f48e34154 108 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 7 103 28.834 T 29-03-2018 IPR022935 ATP-dependent Clp protease adaptor protein ClpS CDC59_RS12675 f40b501c86c3e74425fe029f48e34154 108 Gene3D G3DSA:3.30.1390.10 15 107 2.3E-34 T 29-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CDC59_RS21045 bc5c251db04c80ad7e6126ab27d6e219 164 SUPERFAMILY SSF54909 69 154 1.72E-17 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CDC59_RS21045 bc5c251db04c80ad7e6126ab27d6e219 164 Pfam PF01037 Lrp/AsnC ligand binding domain 74 146 6.2E-20 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CDC59_RS21045 bc5c251db04c80ad7e6126ab27d6e219 164 Gene3D G3DSA:3.30.70.920 60 153 7.2E-20 T 29-03-2018 CDC59_RS21045 bc5c251db04c80ad7e6126ab27d6e219 164 ProSitePatterns PS00519 AsnC-type HTH domain signature. 25 51 - T 29-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site CDC59_RS21045 bc5c251db04c80ad7e6126ab27d6e219 164 SMART SM00344 7 116 2.8E-43 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CDC59_RS21045 bc5c251db04c80ad7e6126ab27d6e219 164 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 7 23 3.4E-17 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CDC59_RS21045 bc5c251db04c80ad7e6126ab27d6e219 164 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 34 53 3.4E-17 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CDC59_RS21045 bc5c251db04c80ad7e6126ab27d6e219 164 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 23 34 3.4E-17 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CDC59_RS21045 bc5c251db04c80ad7e6126ab27d6e219 164 SUPERFAMILY SSF46785 6 66 6.66E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS21045 bc5c251db04c80ad7e6126ab27d6e219 164 Pfam PF13412 Winged helix-turn-helix DNA-binding 8 53 2.8E-19 T 29-03-2018 CDC59_RS21045 bc5c251db04c80ad7e6126ab27d6e219 164 Gene3D G3DSA:1.10.10.10 1 58 9.9E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS11080 62cc29352c9c7e676085cffb83083619 99 Pfam PF12587 Protein of unknown function (DUF3761) 10 99 4.0E-36 T 29-03-2018 IPR022236 Protein of unknown function DUF3761 CDC59_RS16210 814fdd42f79b6815036a27fea3a91d39 130 SUPERFAMILY SSF55298 2 129 2.67E-31 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CDC59_RS16210 814fdd42f79b6815036a27fea3a91d39 130 Pfam PF01042 Endoribonuclease L-PSP 14 128 2.5E-20 T 29-03-2018 IPR006175 YjgF/YER057c/UK114 family CDC59_RS16210 814fdd42f79b6815036a27fea3a91d39 130 Gene3D G3DSA:3.30.1330.40 1 130 6.9E-29 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CDC59_RS17060 d5154e9b8040297f312d9faee1c58100 247 Pfam PF06912 Protein of unknown function (DUF1275) 25 235 1.1E-37 T 29-03-2018 IPR010699 Protein of unknown function DUF1275 CDC59_RS19260 cf7397605c33b4bbf46af211c10a260c 340 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 43 326 2.3E-46 T 29-03-2018 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system CDC59_RS10140 ec89ea127e5514e275b6891de41fbd48 205 SUPERFAMILY SSF52266 17 199 6.11E-49 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain CDC59_RS10140 ec89ea127e5514e275b6891de41fbd48 205 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 24 182 1.5E-24 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain CDC59_RS10140 ec89ea127e5514e275b6891de41fbd48 205 ProSitePatterns PS01098 Lipolytic enzymes "G-D-S-L" family, serine active site. 22 32 - T 29-03-2018 IPR008265 Lipase, GDSL, active site GO:0006629|GO:0016298 Reactome: R-HSA-1482788|Reactome: R-HSA-975634 CDC59_RS10140 ec89ea127e5514e275b6891de41fbd48 205 Gene3D G3DSA:3.40.50.1110 18 201 1.2E-36 T 29-03-2018 CDC59_RS03430 a1cda976180c292d9d35fe2a0b285063 156 PIRSF PIRSF001399 9 155 3.7E-60 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CDC59_RS03430 a1cda976180c292d9d35fe2a0b285063 156 SUPERFAMILY SSF52304 12 153 5.76E-63 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CDC59_RS03430 a1cda976180c292d9d35fe2a0b285063 156 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 156 73.925 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CDC59_RS03430 a1cda976180c292d9d35fe2a0b285063 156 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 13 152 4.4E-61 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CDC59_RS03430 a1cda976180c292d9d35fe2a0b285063 156 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 13 152 3.0E-71 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CDC59_RS03430 a1cda976180c292d9d35fe2a0b285063 156 Pfam PF01220 Dehydroquinase class II 13 149 3.2E-62 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CDC59_RS03430 a1cda976180c292d9d35fe2a0b285063 156 Gene3D G3DSA:3.40.50.9100 8 154 2.6E-68 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CDC59_RS03430 a1cda976180c292d9d35fe2a0b285063 156 ProSitePatterns PS01029 Dehydroquinase class II signature. 16 33 - T 29-03-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CDC59_RS02820 33615312fbd67f9a47697a3da34701c0 114 Gene3D G3DSA:1.20.120.20 16 114 1.6E-10 T 29-03-2018 CDC59_RS10340 182d7d5acc86819b3e8324b822729991 267 SUPERFAMILY SSF64438 7 265 5.13E-78 T 29-03-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic CDC59_RS10340 182d7d5acc86819b3e8324b822729991 267 Gene3D G3DSA:3.60.140.10 2 267 8.0E-93 T 29-03-2018 CDC59_RS10340 182d7d5acc86819b3e8324b822729991 267 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 44 265 4.7E-55 T 29-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase CDC59_RS10340 182d7d5acc86819b3e8324b822729991 267 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 23 264 2.7E-76 T 29-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase CDC59_RS11230 80923515c52cac2aefbe7ac3408ec231 500 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 332 495 1.2E-38 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CDC59_RS11230 80923515c52cac2aefbe7ac3408ec231 500 SUPERFAMILY SSF58104 250 499 1.96E-58 T 29-03-2018 CDC59_RS11230 80923515c52cac2aefbe7ac3408ec231 500 Gene3D G3DSA:1.10.287.950 327 497 3.4E-37 T 29-03-2018 CDC59_RS11230 80923515c52cac2aefbe7ac3408ec231 500 SMART SM00283 272 498 2.4E-61 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CDC59_RS11230 80923515c52cac2aefbe7ac3408ec231 500 Gene3D G3DSA:1.10.287.950 34 326 2.4E-18 T 29-03-2018 CDC59_RS11230 80923515c52cac2aefbe7ac3408ec231 500 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 447 476 1.1E-37 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS11230 80923515c52cac2aefbe7ac3408ec231 500 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 399 428 1.1E-37 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS11230 80923515c52cac2aefbe7ac3408ec231 500 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 370 397 1.1E-37 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS11230 80923515c52cac2aefbe7ac3408ec231 500 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 293 322 1.1E-37 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CDC59_RS11230 80923515c52cac2aefbe7ac3408ec231 500 Pfam PF12729 Four helix bundle sensory module for signal transduction 5 188 1.6E-10 T 29-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain CDC59_RS08310 98f8504fe9c723a052ff2e150945b7fa 385 Pfam PF00487 Fatty acid desaturase 78 320 5.5E-35 T 29-03-2018 IPR005804 Fatty acid desaturase domain GO:0006629 CDC59_RS23150 922b1c886e144c2c4b75d209b741f9e4 383 SUPERFAMILY SSF89796 7 378 1.14E-118 T 29-03-2018 IPR023606 CoA-transferase family III domain CDC59_RS23150 922b1c886e144c2c4b75d209b741f9e4 383 Gene3D G3DSA:3.40.50.10540 4 382 1.4E-118 T 29-03-2018 IPR023606 CoA-transferase family III domain CDC59_RS23150 922b1c886e144c2c4b75d209b741f9e4 383 Pfam PF02515 CoA-transferase family III 10 371 8.1E-114 T 29-03-2018 IPR003673 CoA-transferase family III GO:0003824 CDC59_RS15350 f01348ed4aa9f6dd1b655ab3ab3d0ddd 240 Gene3D G3DSA:1.10.357.10 65 223 5.2E-17 T 29-03-2018 CDC59_RS15350 f01348ed4aa9f6dd1b655ab3ab3d0ddd 240 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 73 5.0E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDC59_RS15350 f01348ed4aa9f6dd1b655ab3ab3d0ddd 240 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 3.2E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDC59_RS15350 f01348ed4aa9f6dd1b655ab3ab3d0ddd 240 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 3.2E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDC59_RS15350 f01348ed4aa9f6dd1b655ab3ab3d0ddd 240 Gene3D G3DSA:1.10.10.60 1 64 2.8E-20 T 29-03-2018 CDC59_RS15350 f01348ed4aa9f6dd1b655ab3ab3d0ddd 240 SUPERFAMILY SSF48498 110 221 6.67E-10 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CDC59_RS15350 f01348ed4aa9f6dd1b655ab3ab3d0ddd 240 SUPERFAMILY SSF46689 14 89 7.18E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS14215 ffc6d88aecced1772fa49c79e7296a08 195 SUPERFAMILY SSF56784 23 187 2.76E-37 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS14215 ffc6d88aecced1772fa49c79e7296a08 195 PIRSF PIRSF006118 14 189 1.9E-71 T 29-03-2018 IPR010023 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase GO:0019143 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 CDC59_RS14215 ffc6d88aecced1772fa49c79e7296a08 195 TIGRFAM TIGR01670 KdsC-phosphatas: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family 27 179 1.5E-47 T 29-03-2018 IPR010023 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase GO:0019143 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 CDC59_RS14215 ffc6d88aecced1772fa49c79e7296a08 195 Gene3D G3DSA:3.40.50.1000 4 189 5.4E-27 T 29-03-2018 IPR023214 HAD-like domain CDC59_RS14250 66b5d1fa7501717ee606eb51deb70ca8 324 Hamap MF_01249 HPr kinase/phosphorylase [hprK]. 5 313 37.42 T 29-03-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 CDC59_RS14250 66b5d1fa7501717ee606eb51deb70ca8 324 Gene3D G3DSA:3.40.1390.20 6 137 4.0E-31 T 29-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CDC59_RS14250 66b5d1fa7501717ee606eb51deb70ca8 324 Pfam PF02603 HPr Serine kinase N terminus 6 135 4.2E-24 T 29-03-2018 IPR011126 HPr(Ser) kinase/phosphorylase, N-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 CDC59_RS14250 66b5d1fa7501717ee606eb51deb70ca8 324 SUPERFAMILY SSF53795 140 306 1.68E-34 T 29-03-2018 CDC59_RS14250 66b5d1fa7501717ee606eb51deb70ca8 324 Pfam PF07475 HPr Serine kinase C-terminal domain 140 305 4.5E-61 T 29-03-2018 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 CDC59_RS14250 66b5d1fa7501717ee606eb51deb70ca8 324 Gene3D G3DSA:3.40.50.300 143 314 7.2E-39 T 29-03-2018 CDC59_RS14250 66b5d1fa7501717ee606eb51deb70ca8 324 TIGRFAM TIGR00679 hpr-ser: HPr(Ser) kinase/phosphatase 10 309 7.7E-96 T 29-03-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 CDC59_RS14250 66b5d1fa7501717ee606eb51deb70ca8 324 SUPERFAMILY SSF75138 5 137 3.53E-30 T 29-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CDC59_RS02555 810c734c2fbb7d90e36801d59a2bda1f 262 Pfam PF01061 ABC-2 type transporter 15 225 1.9E-37 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CDC59_RS02555 810c734c2fbb7d90e36801d59a2bda1f 262 PRINTS PR00164 ABC-2 type transport system membrane protein signature 202 221 1.6E-8 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CDC59_RS02555 810c734c2fbb7d90e36801d59a2bda1f 262 PRINTS PR00164 ABC-2 type transport system membrane protein signature 64 86 1.6E-8 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CDC59_RS02555 810c734c2fbb7d90e36801d59a2bda1f 262 PRINTS PR00164 ABC-2 type transport system membrane protein signature 182 201 1.6E-8 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CDC59_RS02555 810c734c2fbb7d90e36801d59a2bda1f 262 PIRSF PIRSF006648 11 259 1.9E-20 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CDC59_RS04655 0679cca2247ba986d90281a52aa1bf7e 143 Pfam PF16732 Type IV minor pilin ComP, DNA uptake sequence receptor 35 118 8.1E-7 T 29-03-2018 IPR031982 Type IV minor pilin ComP CDC59_RS04655 0679cca2247ba986d90281a52aa1bf7e 143 Gene3D G3DSA:3.30.700.10 7 133 7.2E-10 T 29-03-2018 CDC59_RS04655 0679cca2247ba986d90281a52aa1bf7e 143 Pfam PF07963 Prokaryotic N-terminal methylation motif 2 26 1.0E-7 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS04655 0679cca2247ba986d90281a52aa1bf7e 143 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 6 26 1.4E-7 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS04655 0679cca2247ba986d90281a52aa1bf7e 143 SUPERFAMILY SSF54523 7 141 1.8E-14 T 29-03-2018 CDC59_RS00875 38997e8fb6f745cfa35312bee4a90005 321 Pfam PF07859 alpha/beta hydrolase fold 79 292 4.9E-66 T 29-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CDC59_RS00875 38997e8fb6f745cfa35312bee4a90005 321 SUPERFAMILY SSF53474 21 312 4.84E-59 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS00875 38997e8fb6f745cfa35312bee4a90005 321 Gene3D G3DSA:3.40.50.1820 1 314 6.8E-53 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS01715 8066970dcb5e6a290f7047745bae29cb 481 Pfam PF05134 Type II secretion system (T2SS), protein L 5 317 7.2E-80 T 29-03-2018 IPR024230 GspL, cytoplasmic actin-ATPase-like domain CDC59_RS01715 8066970dcb5e6a290f7047745bae29cb 481 Pfam PF12693 GspL periplasmic domain 323 479 2.2E-38 T 29-03-2018 IPR025691 GspL periplasmic domain CDC59_RS01715 8066970dcb5e6a290f7047745bae29cb 481 SUPERFAMILY SSF53067 4 165 1.06E-18 T 29-03-2018 CDC59_RS18110 22a4d553535142f3ada7aac1255ff42b 476 Pfam PF00324 Amino acid permease 27 457 1.4E-106 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CDC59_RS18110 22a4d553535142f3ada7aac1255ff42b 476 ProSitePatterns PS00218 Amino acid permeases signature. 52 82 - T 29-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CDC59_RS18110 22a4d553535142f3ada7aac1255ff42b 476 PIRSF PIRSF006060 2 472 8.9E-64 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CDC59_RS19385 38e895efaba2fb308ec121b748786553 238 SMART SM00873 63 210 8.7E-5 T 29-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CDC59_RS19385 38e895efaba2fb308ec121b748786553 238 Pfam PF03483 B3/4 domain 64 195 6.1E-14 T 29-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CDC59_RS19385 38e895efaba2fb308ec121b748786553 238 SUPERFAMILY SSF56037 53 194 2.62E-25 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CDC59_RS19385 38e895efaba2fb308ec121b748786553 238 Gene3D G3DSA:3.50.40.10 60 210 5.9E-20 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CDC59_RS11640 f9f0214ddabd105c4e1bc978f8f1baf1 210 TIGRFAM TIGR00101 ureG: urease accessory protein UreG 9 203 2.8E-100 T 29-03-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 CDC59_RS11640 f9f0214ddabd105c4e1bc978f8f1baf1 210 SUPERFAMILY SSF52540 7 200 4.79E-35 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS11640 f9f0214ddabd105c4e1bc978f8f1baf1 210 Hamap MF_01389 Urease accessory protein UreG [ureG]. 7 205 46.895 T 29-03-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 CDC59_RS11640 f9f0214ddabd105c4e1bc978f8f1baf1 210 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 11 181 8.3E-38 T 29-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CDC59_RS11640 f9f0214ddabd105c4e1bc978f8f1baf1 210 Gene3D G3DSA:3.40.50.300 8 206 4.0E-19 T 29-03-2018 CDC59_RS11640 f9f0214ddabd105c4e1bc978f8f1baf1 210 PIRSF PIRSF005624 2 210 7.8E-48 T 29-03-2018 IPR012202 [NiFe]-hydrogenase/urease maturation factor, Ni2-binding GTPase GO:0003924|GO:0016151 CDC59_RS21805 752723aa5a96121433a39223a9d6ddd5 486 Pfam PF02321 Outer membrane efflux protein 299 469 3.8E-17 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CDC59_RS21805 752723aa5a96121433a39223a9d6ddd5 486 Pfam PF02321 Outer membrane efflux protein 91 272 2.8E-25 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CDC59_RS21805 752723aa5a96121433a39223a9d6ddd5 486 Gene3D G3DSA:1.20.1600.10 41 478 2.6E-60 T 29-03-2018 CDC59_RS21805 752723aa5a96121433a39223a9d6ddd5 486 SUPERFAMILY SSF56954 31 474 3.66E-68 T 29-03-2018 CDC59_RS13930 410e66c8a91b6ae6237da601c650bfcd 245 Pfam PF04367 Protein of unknown function (DUF502) 63 168 4.1E-37 T 29-03-2018 IPR007462 Protein of unknown function DUF502 CDC59_RS08690 5cd5c15a4272f4684ed2a08a86886638 208 SUPERFAMILY SSF109755 123 200 6.93E-5 T 29-03-2018 CDC59_RS08690 5cd5c15a4272f4684ed2a08a86886638 208 Gene3D G3DSA:1.20.58.220 101 207 6.2E-12 T 29-03-2018 CDC59_RS08690 5cd5c15a4272f4684ed2a08a86886638 208 Pfam PF01865 Protein of unknown function DUF47 8 206 7.0E-35 T 29-03-2018 IPR018445 Putative phosphate transport regulator CDC59_RS06995 4e9ff0d8fdeee1665eb032e06fbcce8b 239 SUPERFAMILY SSF55186 98 235 3.01E-29 T 29-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 CDC59_RS06995 4e9ff0d8fdeee1665eb032e06fbcce8b 239 Pfam PF01411 tRNA synthetases class II (A) 17 97 9.5E-8 T 29-03-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 CDC59_RS06995 4e9ff0d8fdeee1665eb032e06fbcce8b 239 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 191 234 3.1E-11 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CDC59_RS06995 4e9ff0d8fdeee1665eb032e06fbcce8b 239 SMART SM00863 191 234 1.6E-12 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CDC59_RS06995 4e9ff0d8fdeee1665eb032e06fbcce8b 239 SUPERFAMILY SSF50447 2 76 6.0E-12 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CDC59_RS06995 4e9ff0d8fdeee1665eb032e06fbcce8b 239 Gene3D G3DSA:3.30.980.10 95 239 3.5E-26 T 29-03-2018 CDC59_RS05625 71b1ecf69b4e7f1e71badaeed6a1088d 426 Gene3D G3DSA:1.10.150.130 76 222 3.5E-5 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal CDC59_RS05625 71b1ecf69b4e7f1e71badaeed6a1088d 426 SUPERFAMILY SSF56349 145 359 3.83E-32 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CDC59_RS05625 71b1ecf69b4e7f1e71badaeed6a1088d 426 Pfam PF00589 Phage integrase family 225 358 8.0E-10 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CDC59_RS05625 71b1ecf69b4e7f1e71badaeed6a1088d 426 Gene3D G3DSA:1.10.443.10 223 424 3.7E-25 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CDC59_RS13980 eea0e1f91a270637f96172397290c78b 147 Pfam PF01230 HIT domain 27 104 1.6E-12 T 29-03-2018 IPR001310 Histidine triad (HIT) protein CDC59_RS13980 eea0e1f91a270637f96172397290c78b 147 SUPERFAMILY SSF54197 7 126 2.01E-36 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 CDC59_RS13980 eea0e1f91a270637f96172397290c78b 147 PIRSF PIRSF000714 8 146 1.4E-39 T 29-03-2018 IPR026026 Histidine triad hydrolase, Hint-type CDC59_RS13980 eea0e1f91a270637f96172397290c78b 147 Gene3D G3DSA:3.30.428.10 2 145 4.0E-29 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 CDC59_RS03495 f5285a66b2e6c520f2459455c2898cfc 409 Pfam PF01545 Cation efflux family 35 324 6.0E-41 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CDC59_RS03495 f5285a66b2e6c520f2459455c2898cfc 409 SUPERFAMILY SSF161111 257 325 1.57E-49 T 29-03-2018 CDC59_RS03495 f5285a66b2e6c520f2459455c2898cfc 409 SUPERFAMILY SSF161111 28 160 1.57E-49 T 29-03-2018 CDC59_RS03495 f5285a66b2e6c520f2459455c2898cfc 409 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 31 399 2.4E-66 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CDC59_RS03495 f5285a66b2e6c520f2459455c2898cfc 409 Gene3D G3DSA:1.20.1510.10 29 324 9.8E-50 T 29-03-2018 CDC59_RS18400 c91ef3896752c6f0aa6e586dfae9fc65 405 Gene3D G3DSA:1.20.91.10 242 323 3.6E-9 T 29-03-2018 CDC59_RS18400 c91ef3896752c6f0aa6e586dfae9fc65 405 Pfam PF00999 Sodium/hydrogen exchanger family 12 387 7.0E-83 T 29-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CDC59_RS14435 4f54235b809d33171b447b2a573160a7 256 Pfam PF02104 SURF1 family 21 231 1.2E-33 T 29-03-2018 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS01815 ae4edb63790921a46e524d3de5ecffed 195 SUPERFAMILY SSF54427 6 138 2.51E-9 T 29-03-2018 IPR032710 NTF2-like domain CDC59_RS01815 ae4edb63790921a46e524d3de5ecffed 195 Gene3D G3DSA:3.10.450.50 2 144 1.2E-7 T 29-03-2018 CDC59_RS10785 b036139feb94c4ef190d2b071ae576ec 444 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 5 422 1.5E-168 T 29-03-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 CDC59_RS10785 b036139feb94c4ef190d2b071ae576ec 444 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 199 213 - T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CDC59_RS10785 b036139feb94c4ef190d2b071ae576ec 444 Gene3D G3DSA:3.90.1150.10 291 437 3.5E-48 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS10785 b036139feb94c4ef190d2b071ae576ec 444 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 7 423 5.1E-128 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CDC59_RS10785 b036139feb94c4ef190d2b071ae576ec 444 Gene3D G3DSA:3.40.640.10 4 289 8.1E-58 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDC59_RS10785 b036139feb94c4ef190d2b071ae576ec 444 SUPERFAMILY SSF53383 5 423 3.52E-119 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS10785 b036139feb94c4ef190d2b071ae576ec 444 PIRSF PIRSF001434 1 426 8.9E-128 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CDC59_RS14610 0ee2bbfdc9b49c344e7a777d03ed8eb7 182 Gene3D G3DSA:3.40.30.10 37 182 1.2E-32 T 29-03-2018 CDC59_RS14610 0ee2bbfdc9b49c344e7a777d03ed8eb7 182 Pfam PF08534 Redoxin 43 168 8.0E-25 T 29-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 CDC59_RS14610 0ee2bbfdc9b49c344e7a777d03ed8eb7 182 SUPERFAMILY SSF52833 41 180 2.23E-35 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS08720 ecaf0f669c59a655d61d16f89257ac0d 297 SUPERFAMILY SSF88713 15 41 8.58E-22 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CDC59_RS08720 ecaf0f669c59a655d61d16f89257ac0d 297 SUPERFAMILY SSF88713 86 267 8.58E-22 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CDC59_RS08720 ecaf0f669c59a655d61d16f89257ac0d 297 Pfam PF01522 Polysaccharide deacetylase 15 170 5.0E-8 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CDC59_RS08720 ecaf0f669c59a655d61d16f89257ac0d 297 Gene3D G3DSA:3.20.20.370 3 279 4.4E-22 T 29-03-2018 CDC59_RS02495 162d1b85c003e3e8e7e53aa94c9a9fde 224 Pfam PF03922 OmpW family 35 224 1.6E-44 T 29-03-2018 IPR005618 Outer membrane protein, OmpW GO:0019867 CDC59_RS02495 162d1b85c003e3e8e7e53aa94c9a9fde 224 SUPERFAMILY SSF56925 35 224 1.15E-29 T 29-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CDC59_RS02495 162d1b85c003e3e8e7e53aa94c9a9fde 224 Gene3D G3DSA:2.40.160.20 34 224 6.0E-29 T 29-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CDC59_RS18485 a33c5a9d8c343e304a0599f00307be24 210 SUPERFAMILY SSF53335 18 204 1.66E-35 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS18485 a33c5a9d8c343e304a0599f00307be24 210 Gene3D G3DSA:3.40.50.150 8 210 2.4E-32 T 29-03-2018 CDC59_RS18485 a33c5a9d8c343e304a0599f00307be24 210 Pfam PF13649 Methyltransferase domain 54 143 9.9E-17 T 29-03-2018 CDC59_RS20685 4639d7e49b81d12a03e921431a86156f 398 Gene3D G3DSA:1.50.10.10 27 380 8.1E-30 T 29-03-2018 CDC59_RS20685 4639d7e49b81d12a03e921431a86156f 398 SUPERFAMILY SSF48208 27 374 1.02E-59 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CDC59_RS05290 e234f983a85f4b2aa0db1d7ef13bae0f 160 Pfam PF10908 Protein of unknown function (DUF2778) 25 149 1.3E-37 T 29-03-2018 IPR021225 Protein of unknown function DUF2778 CDC59_RS07010 b99059b63d7ebd7b8f6def5a80db920c 165 Gene3D G3DSA:3.40.470.10 8 165 8.2E-44 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CDC59_RS07010 b99059b63d7ebd7b8f6def5a80db920c 165 SUPERFAMILY SSF52141 12 163 3.4E-36 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CDC59_RS07010 b99059b63d7ebd7b8f6def5a80db920c 165 TIGRFAM TIGR04274 hypoxanDNAglyco: DNA-deoxyinosine glycosylase 11 159 5.7E-50 T 29-03-2018 IPR026353 Hypoxanthine-DNA glycosylase CDC59_RS07010 b99059b63d7ebd7b8f6def5a80db920c 165 Pfam PF03167 Uracil DNA glycosylase superfamily 16 162 3.2E-6 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CDC59_RS07010 b99059b63d7ebd7b8f6def5a80db920c 165 SMART SM00987 13 163 2.7E-10 T 29-03-2018 CDC59_RS07010 b99059b63d7ebd7b8f6def5a80db920c 165 SMART SM00986 13 163 2.7E-10 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CDC59_RS00480 560dd1604158369c7321a0f9be7cc34b 348 Gene3D G3DSA:3.40.190.10 140 346 1.2E-24 T 29-03-2018 CDC59_RS00480 560dd1604158369c7321a0f9be7cc34b 348 Pfam PF09084 NMT1/THI5 like 56 269 7.0E-22 T 29-03-2018 IPR015168 SsuA/THI5-like CDC59_RS00480 560dd1604158369c7321a0f9be7cc34b 348 SUPERFAMILY SSF53850 41 285 2.32E-35 T 29-03-2018 CDC59_RS00480 560dd1604158369c7321a0f9be7cc34b 348 Gene3D G3DSA:3.40.190.10 35 139 9.8E-9 T 29-03-2018 CDC59_RS05785 0180484088e690cf118e47a9cb46b019 328 Pfam PF01609 Transposase DDE domain 138 312 1.9E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS05785 0180484088e690cf118e47a9cb46b019 328 Pfam PF05598 Transposase domain (DUF772) 51 126 2.8E-22 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS16870 d4d71ca0bd7efbd8ee35ba8bdcf5aaeb 333 Gene3D G3DSA:3.20.20.70 4 325 2.0E-37 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS16870 d4d71ca0bd7efbd8ee35ba8bdcf5aaeb 333 Pfam PF03060 Nitronate monooxygenase 23 307 3.3E-23 T 29-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CDC59_RS16870 d4d71ca0bd7efbd8ee35ba8bdcf5aaeb 333 SUPERFAMILY SSF51412 6 292 4.76E-60 T 29-03-2018 CDC59_RS13790 b0564ac308b7961c4317cec2486de4f3 130 Pfam PF00380 Ribosomal protein S9/S16 10 130 2.7E-44 T 29-03-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 CDC59_RS13790 b0564ac308b7961c4317cec2486de4f3 130 SUPERFAMILY SSF54211 5 130 1.02E-44 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CDC59_RS13790 b0564ac308b7961c4317cec2486de4f3 130 Gene3D G3DSA:3.30.230.10 4 130 4.7E-50 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CDC59_RS13790 b0564ac308b7961c4317cec2486de4f3 130 ProSitePatterns PS00360 Ribosomal protein S9 signature. 69 87 - T 29-03-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 CDC59_RS13790 b0564ac308b7961c4317cec2486de4f3 130 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 130 31.306 T 29-03-2018 IPR023035 Ribosomal protein S9, bacterial/plastid CDC59_RS02845 cf440612416f33584fbb6a36b1eaf28b 127 Pfam PF05400 Flagellar protein FliT 36 121 1.4E-21 T 29-03-2018 IPR008622 Flagellar protein FliT CDC59_RS02845 cf440612416f33584fbb6a36b1eaf28b 127 Gene3D G3DSA:1.20.58.380 20 105 2.2E-25 T 29-03-2018 CDC59_RS19650 b4b5d55c9ec6284cf3998b2a56d64e6f 157 TIGRFAM TIGR03357 VI_zyme: type VI secretion system lysozyme-like protein 5 152 9.8E-34 T 29-03-2018 IPR017737 Type VI secretion system, lysozyme-related protein CDC59_RS19650 b4b5d55c9ec6284cf3998b2a56d64e6f 157 Pfam PF04965 Gene 25-like lysozyme 32 131 8.2E-20 T 29-03-2018 IPR007048 GpW/Gp25/anti-adapter protein IraD CDC59_RS19650 b4b5d55c9ec6284cf3998b2a56d64e6f 157 Gene3D G3DSA:3.10.450.40 4 147 8.5E-24 T 29-03-2018 CDC59_RS19650 b4b5d55c9ec6284cf3998b2a56d64e6f 157 SUPERFAMILY SSF160719 37 145 1.83E-10 T 29-03-2018 CDC59_RS10135 64cc722587efb5c99932dcf20226d6bb 236 Pfam PF00005 ABC transporter 28 177 7.7E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS10135 64cc722587efb5c99932dcf20226d6bb 236 Gene3D G3DSA:3.40.50.300 5 236 2.3E-63 T 29-03-2018 CDC59_RS10135 64cc722587efb5c99932dcf20226d6bb 236 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS10135 64cc722587efb5c99932dcf20226d6bb 236 SMART SM00382 37 230 1.1E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS10135 64cc722587efb5c99932dcf20226d6bb 236 SUPERFAMILY SSF52540 8 231 1.52E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS04775 fde239636c5300fca211ad7d9fcf01f4 372 SUPERFAMILY SSF51569 27 369 5.04E-133 T 29-03-2018 CDC59_RS04775 fde239636c5300fca211ad7d9fcf01f4 372 Gene3D G3DSA:3.20.20.70 28 372 1.3E-128 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS04775 fde239636c5300fca211ad7d9fcf01f4 372 Pfam PF00793 DAHP synthetase I family 64 357 2.5E-97 T 29-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 CDC59_RS04775 fde239636c5300fca211ad7d9fcf01f4 372 PIRSF PIRSF001361 15 372 9.4E-160 T 29-03-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CDC59_RS04775 fde239636c5300fca211ad7d9fcf01f4 372 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 26 370 7.1E-153 T 29-03-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CDC59_RS13440 98d504e67f3e92030e12693feaa30855 208 Pfam PF11136 Protein of unknown function (DUF2889) 13 137 8.5E-45 T 29-03-2018 IPR021312 Protein of unknown function DUF2889 CDC59_RS19595 53b1d48e603155c0cc07526a17d33556 350 Gene3D G3DSA:1.10.3920.10 124 280 7.9E-46 T 29-03-2018 IPR028983 PA2201-like, C-terminal CDC59_RS19595 53b1d48e603155c0cc07526a17d33556 350 Pfam PF08929 Domain of unknown function (DUF1911) 167 272 3.0E-23 T 29-03-2018 IPR015025 Domain of unknown function DUF1911 CDC59_RS19595 53b1d48e603155c0cc07526a17d33556 350 SUPERFAMILY SSF140731 124 280 2.09E-48 T 29-03-2018 IPR028983 PA2201-like, C-terminal CDC59_RS19595 53b1d48e603155c0cc07526a17d33556 350 Pfam PF08928 Domain of unknown function (DUF1910) 18 154 2.1E-6 T 29-03-2018 IPR015024 Domain of unknown function DUF1910 CDC59_RS05305 91598f8fc1a8838cd28764a0cb23b264 84 SUPERFAMILY SSF160059 5 58 1.63E-5 T 29-03-2018 CDC59_RS01510 8d946d311e643b78eb61a351adf38c2d 719 Gene3D G3DSA:3.50.50.60 29 702 9.3E-17 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS01510 8d946d311e643b78eb61a351adf38c2d 719 SUPERFAMILY SSF51905 60 424 1.2E-14 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS01510 8d946d311e643b78eb61a351adf38c2d 719 SUPERFAMILY SSF51905 647 686 1.2E-14 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS01510 8d946d311e643b78eb61a351adf38c2d 719 SUPERFAMILY SSF51905 458 491 1.2E-14 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS01510 8d946d311e643b78eb61a351adf38c2d 719 Pfam PF01593 Flavin containing amine oxidoreductase 123 555 3.0E-4 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 CDC59_RS00235 d7b0ee983a06c0e2727773984025e827 448 PRINTS PR00344 Bacterial sensor protein C-terminal signature 391 409 1.9E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS00235 d7b0ee983a06c0e2727773984025e827 448 PRINTS PR00344 Bacterial sensor protein C-terminal signature 415 428 1.9E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS00235 d7b0ee983a06c0e2727773984025e827 448 PRINTS PR00344 Bacterial sensor protein C-terminal signature 362 376 1.9E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CDC59_RS00235 d7b0ee983a06c0e2727773984025e827 448 Gene3D G3DSA:3.30.565.10 284 438 4.6E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS00235 d7b0ee983a06c0e2727773984025e827 448 SUPERFAMILY SSF55874 291 432 8.38E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS00235 d7b0ee983a06c0e2727773984025e827 448 SMART SM00387 312 431 9.1E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS00235 d7b0ee983a06c0e2727773984025e827 448 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 315 429 4.4E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CDC59_RS01290 5e77cd80da2569b77c7d3b385df3c9cd 110 Pfam PF15581 Immunity protein 58 9 108 4.4E-14 T 29-03-2018 IPR028968 Immunity protein 58 CDC59_RS16650 4f1cc7da2c5c41e01aef557eab3a9336 377 Pfam PF09937 Uncharacterized protein conserved in bacteria (DUF2169) 22 324 2.8E-89 T 29-03-2018 IPR018683 Domain of unknown function DUF2169 CDC59_RS18805 866f505ca8b399acbaebabcfc3c433bd 221 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 217 9.7E-20 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDC59_RS18805 866f505ca8b399acbaebabcfc3c433bd 221 Pfam PF00072 Response regulator receiver domain 4 113 1.3E-22 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS18805 866f505ca8b399acbaebabcfc3c433bd 221 Gene3D G3DSA:1.10.10.10 121 220 1.4E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS18805 866f505ca8b399acbaebabcfc3c433bd 221 SMART SM00862 146 217 6.2E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CDC59_RS18805 866f505ca8b399acbaebabcfc3c433bd 221 SMART SM00448 2 113 3.0E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS18805 866f505ca8b399acbaebabcfc3c433bd 221 SUPERFAMILY SSF52172 4 174 7.62E-34 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS18805 866f505ca8b399acbaebabcfc3c433bd 221 Gene3D G3DSA:3.40.50.2300 2 120 4.6E-29 T 29-03-2018 CDC59_RS19270 4abd328c4709c6d94929e118e159fb4f 530 Gene3D G3DSA:1.20.1250.20 18 209 1.1E-29 T 29-03-2018 CDC59_RS19270 4abd328c4709c6d94929e118e159fb4f 530 Gene3D G3DSA:1.20.1250.20 263 525 8.5E-32 T 29-03-2018 CDC59_RS19270 4abd328c4709c6d94929e118e159fb4f 530 Pfam PF07690 Major Facilitator Superfamily 27 421 3.9E-50 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDC59_RS19270 4abd328c4709c6d94929e118e159fb4f 530 SUPERFAMILY SSF103473 24 213 7.46E-63 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS19270 4abd328c4709c6d94929e118e159fb4f 530 SUPERFAMILY SSF103473 488 521 7.46E-63 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS19270 4abd328c4709c6d94929e118e159fb4f 530 SUPERFAMILY SSF103473 260 431 7.46E-63 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS12535 dd91728f3d3c8caa9f2492d028444a0a 258 Gene3D G3DSA:3.40.50.300 1 257 1.6E-57 T 29-03-2018 CDC59_RS12535 dd91728f3d3c8caa9f2492d028444a0a 258 Pfam PF00005 ABC transporter 23 183 8.1E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS12535 dd91728f3d3c8caa9f2492d028444a0a 258 SMART SM00382 32 238 7.6E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS12535 dd91728f3d3c8caa9f2492d028444a0a 258 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 232 254 2.1E-10 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CDC59_RS12535 dd91728f3d3c8caa9f2492d028444a0a 258 SUPERFAMILY SSF52540 6 254 5.94E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS05310 e072484e5d6ee04f18ccc34f417f4b84 164 Pfam PF07030 Protein of unknown function (DUF1320) 4 144 1.1E-11 T 29-03-2018 IPR009752 Bacteriophage Mu, Gp36 CDC59_RS22600 5cb94b9123122ada1fc750d365253f39 283 Pfam PF01925 Sulfite exporter TauE/SafE 29 276 1.9E-37 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CDC59_RS13825 0e302f10f735e61c2a0c770235fdf280 95 SUPERFAMILY SSF53659 2 86 1.58E-13 T 29-03-2018 CDC59_RS13825 0e302f10f735e61c2a0c770235fdf280 95 Gene3D G3DSA:3.40.718.10 1 94 4.1E-13 T 29-03-2018 CDC59_RS13825 0e302f10f735e61c2a0c770235fdf280 95 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 6 82 5.9E-5 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CDC59_RS05455 77f9900f40989eaac1ad91844a15b569 189 Pfam PF09832 Uncharacterized protein conserved in bacteria (DUF2059) 116 169 7.3E-13 T 29-03-2018 IPR018637 Domain of unknown function DUF2059 CDC59_RS01295 d87f69a8c5a5086cd2edd61325592b7c 127 Pfam PF11042 Protein of unknown function (DUF2750) 21 120 3.6E-26 T 29-03-2018 IPR021284 Protein of unknown function DUF2750 CDC59_RS19125 1f9844868ee20538ae83b4e7848f25e7 109 Gene3D G3DSA:3.40.30.10 3 103 8.9E-24 T 29-03-2018 CDC59_RS19125 1f9844868ee20538ae83b4e7848f25e7 109 SUPERFAMILY SSF52833 6 99 6.82E-23 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS19460 6689ddf4494a5da4862a62193defd399 350 Gene3D G3DSA:1.10.3470.10 97 345 2.0E-23 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CDC59_RS19460 6689ddf4494a5da4862a62193defd399 350 Gene3D G3DSA:1.10.3470.10 3 93 1.1E-4 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CDC59_RS19460 6689ddf4494a5da4862a62193defd399 350 Pfam PF02653 Branched-chain amino acid transport system / permease component 12 335 8.6E-17 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CDC59_RS17575 c33b594bd93d6e14f5db7af5c21a3e9a 188 Gene3D G3DSA:1.20.1550.10 2 176 9.5E-27 T 29-03-2018 IPR023380 Disulphide bond formation protein DsbB-like domain CDC59_RS17575 c33b594bd93d6e14f5db7af5c21a3e9a 188 SUPERFAMILY SSF158442 13 123 1.7E-19 T 29-03-2018 IPR023380 Disulphide bond formation protein DsbB-like domain CDC59_RS17575 c33b594bd93d6e14f5db7af5c21a3e9a 188 Pfam PF02600 Disulfide bond formation protein DsbB 13 90 2.3E-10 T 29-03-2018 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 CDC59_RS01200 2d279859c301a2771703004472dede1a 275 Gene3D G3DSA:1.10.760.10 51 150 1.8E-16 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS01200 2d279859c301a2771703004472dede1a 275 Gene3D G3DSA:1.10.760.10 164 265 2.0E-18 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS01200 2d279859c301a2771703004472dede1a 275 PIRSF PIRSF038455 5 275 5.4E-72 T 29-03-2018 IPR025710 SoxAX cytochrome complex subunit A GO:0009055|GO:0016491|GO:0019417|GO:0020037|GO:0070069 CDC59_RS01200 2d279859c301a2771703004472dede1a 275 SUPERFAMILY SSF46626 36 155 6.58E-24 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS01200 2d279859c301a2771703004472dede1a 275 TIGRFAM TIGR04484 thiosulf_SoxA: sulfur oxidation c-type cytochrome SoxA 49 275 6.0E-74 T 29-03-2018 IPR025710 SoxAX cytochrome complex subunit A GO:0009055|GO:0016491|GO:0019417|GO:0020037|GO:0070069 CDC59_RS01200 2d279859c301a2771703004472dede1a 275 SUPERFAMILY SSF46626 160 274 5.01E-30 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS11660 b6e1638fc38845c16ecc4552ebab9af8 101 TIGRFAM TIGR00192 urease_beta: urease, beta subunit 1 100 3.1E-44 T 29-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CDC59_RS11660 b6e1638fc38845c16ecc4552ebab9af8 101 Pfam PF00699 Urease beta subunit 3 100 1.5E-44 T 29-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CDC59_RS11660 b6e1638fc38845c16ecc4552ebab9af8 101 Hamap MF_01954 Urease subunit beta [ureB]. 1 101 31.51 T 29-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CDC59_RS11660 b6e1638fc38845c16ecc4552ebab9af8 101 Gene3D G3DSA:2.10.150.10 1 101 1.3E-46 T 29-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CDC59_RS11660 b6e1638fc38845c16ecc4552ebab9af8 101 SUPERFAMILY SSF51278 1 101 1.7E-47 T 29-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CDC59_RS03245 da67414cdb15d873feb2b48dedb47688 103 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 103 27.529 T 29-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS03245 da67414cdb15d873feb2b48dedb47688 103 ProSitePatterns PS01169 Ribosomal protein L21 signature. 72 94 - T 29-03-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS03245 da67414cdb15d873feb2b48dedb47688 103 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 102 1.1E-37 T 29-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS03245 da67414cdb15d873feb2b48dedb47688 103 SUPERFAMILY SSF141091 1 102 1.44E-39 T 29-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS03245 da67414cdb15d873feb2b48dedb47688 103 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 101 2.2E-42 T 29-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS15325 2192508e517dd0ee6d90fd5bee99be06 141 Pfam PF04138 GtrA-like protein 20 139 6.4E-18 T 29-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 CDC59_RS08375 bd481bceb9a08a612937477c5347f589 330 Gene3D G3DSA:2.130.10.10 19 115 1.0E-14 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CDC59_RS08375 bd481bceb9a08a612937477c5347f589 330 Gene3D G3DSA:2.130.10.10 116 235 2.4E-21 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CDC59_RS08375 bd481bceb9a08a612937477c5347f589 330 SUPERFAMILY SSF50974 15 323 3.27E-70 T 29-03-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 CDC59_RS08375 bd481bceb9a08a612937477c5347f589 330 Pfam PF10282 Lactonase, 7-bladed beta-propeller 39 303 2.3E-12 T 29-03-2018 IPR019405 Lactonase, 7-bladed beta propeller CDC59_RS08375 bd481bceb9a08a612937477c5347f589 330 Gene3D G3DSA:2.130.10.10 236 325 2.9E-11 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CDC59_RS03465 bdffc7b060d4cdc67dc8b1072e1f675b 304 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 241 284 4.5E-5 T 29-03-2018 IPR006260 TonB, C-terminal GO:0006810 CDC59_RS03465 bdffc7b060d4cdc67dc8b1072e1f675b 304 Gene3D G3DSA:3.30.1150.10 56 304 2.3E-18 T 29-03-2018 CDC59_RS03465 bdffc7b060d4cdc67dc8b1072e1f675b 304 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 241 293 1.2E-7 T 29-03-2018 IPR006260 TonB, C-terminal GO:0006810 CDC59_RS03465 bdffc7b060d4cdc67dc8b1072e1f675b 304 SUPERFAMILY SSF74653 180 295 5.49E-17 T 29-03-2018 CDC59_RS18415 c3b1c3f76d88cf3f76a2c5cd66dc9f05 616 Pfam PF16861 Carbamoyltransferase C-terminus 408 597 3.1E-74 T 29-03-2018 IPR031730 Carbamoyltransferase, C-terminal CDC59_RS18415 c3b1c3f76d88cf3f76a2c5cd66dc9f05 616 SUPERFAMILY SSF53067 6 83 2.33E-21 T 29-03-2018 CDC59_RS18415 c3b1c3f76d88cf3f76a2c5cd66dc9f05 616 SUPERFAMILY SSF53067 134 219 2.33E-21 T 29-03-2018 CDC59_RS18415 c3b1c3f76d88cf3f76a2c5cd66dc9f05 616 SUPERFAMILY SSF53067 257 353 2.33E-21 T 29-03-2018 CDC59_RS18415 c3b1c3f76d88cf3f76a2c5cd66dc9f05 616 Gene3D G3DSA:3.30.420.40 3 154 1.1E-27 T 29-03-2018 CDC59_RS18415 c3b1c3f76d88cf3f76a2c5cd66dc9f05 616 Pfam PF02543 Carbamoyltransferase N-terminus 8 351 7.7E-94 T 29-03-2018 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 CDC59_RS01725 f991ea15309870a0935076d764133e2b 242 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 12 32 - T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS01725 f991ea15309870a0935076d764133e2b 242 SUPERFAMILY SSF54523 14 92 2.79E-9 T 29-03-2018 CDC59_RS01725 f991ea15309870a0935076d764133e2b 242 Gene3D G3DSA:3.30.700.10 14 232 1.5E-7 T 29-03-2018 CDC59_RS01725 f991ea15309870a0935076d764133e2b 242 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 12 33 2.9E-7 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS01725 f991ea15309870a0935076d764133e2b 242 Pfam PF07963 Prokaryotic N-terminal methylation motif 10 33 2.0E-8 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CDC59_RS08800 cba7842101b6ca1bfe4fd5d6788320d7 724 Hamap MF_01906 D-(-)-3-hydroxybutyrate oligomer hydrolase. 3 724 34.251 T 29-03-2018 IPR016582 D-(-)-3-hydroxybutyrate oligomer hydrolase, putative GO:0005615|GO:0019605|GO:0047989 KEGG: 00650+3.1.1.22 CDC59_RS08800 cba7842101b6ca1bfe4fd5d6788320d7 724 PIRSF PIRSF011409 1 724 0.0 T 29-03-2018 IPR016582 D-(-)-3-hydroxybutyrate oligomer hydrolase, putative GO:0005615|GO:0019605|GO:0047989 KEGG: 00650+3.1.1.22 CDC59_RS08800 cba7842101b6ca1bfe4fd5d6788320d7 724 Pfam PF10605 3HB-oligomer hydrolase (3HBOH) 36 723 0.0 T 29-03-2018 IPR016582 D-(-)-3-hydroxybutyrate oligomer hydrolase, putative GO:0005615|GO:0019605|GO:0047989 KEGG: 00650+3.1.1.22 CDC59_RS16060 64c932a4a1cc57bbe8d9400183319fcb 257 Pfam PF12138 Spherulation-specific family 4 29 253 2.4E-46 T 29-03-2018 IPR021986 Spherulation-specific family 4 CDC59_RS16250 8fb741f723f746d75350bc97f7ae18a1 199 Pfam PF00583 Acetyltransferase (GNAT) family 91 161 3.5E-6 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CDC59_RS16250 8fb741f723f746d75350bc97f7ae18a1 199 Gene3D G3DSA:3.40.630.30 15 186 6.8E-21 T 29-03-2018 CDC59_RS16250 8fb741f723f746d75350bc97f7ae18a1 199 SUPERFAMILY SSF55729 20 165 6.03E-20 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDC59_RS00230 e0525d574f386df1945013f8ca88dd80 166 Pfam PF04314 Copper chaperone PCu(A)C 32 133 2.4E-33 T 29-03-2018 IPR007410 Copper chaperone PCuAC CDC59_RS00230 e0525d574f386df1945013f8ca88dd80 166 SUPERFAMILY SSF110087 10 144 1.19E-43 T 29-03-2018 IPR007410 Copper chaperone PCuAC CDC59_RS19070 a4aec7c2f5364def556765aa73414043 200 SUPERFAMILY SSF52540 11 200 2.15E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS19070 a4aec7c2f5364def556765aa73414043 200 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 29 200 3.3E-61 T 29-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 CDC59_RS19070 a4aec7c2f5364def556765aa73414043 200 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 27 200 7.4E-69 T 29-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 CDC59_RS19070 a4aec7c2f5364def556765aa73414043 200 Gene3D G3DSA:3.40.50.300 8 200 1.9E-71 T 29-03-2018 CDC59_RS19070 a4aec7c2f5364def556765aa73414043 200 PIRSF PIRSF015617 3 200 1.7E-71 T 29-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 CDC59_RS22245 c747cae93a637656cc7d2d992eb0cab8 250 Pfam PF16074 Type IV Pilus-assembly protein W 168 232 4.9E-12 T 29-03-2018 IPR032092 Type IV Pilus-assembly protein W GO:0043683 CDC59_RS05355 dbe32b75945949a3ea5e2d627f177a5d 192 Pfam PF06890 Bacteriophage Mu Gp45 protein 26 156 6.2E-26 T 29-03-2018 IPR014462 Phage-associated protein Gp45 CDC59_RS05355 dbe32b75945949a3ea5e2d627f177a5d 192 PIRSF PIRSF012337 3 191 6.7E-28 T 29-03-2018 IPR014462 Phage-associated protein Gp45 CDC59_RS10770 925daa69ed12fcd074643f0690b636f3 144 SUPERFAMILY SSF54534 35 142 3.14E-45 T 29-03-2018 CDC59_RS10770 925daa69ed12fcd074643f0690b636f3 144 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 52 140 9.5E-31 T 29-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain CDC59_RS10770 925daa69ed12fcd074643f0690b636f3 144 Gene3D G3DSA:3.10.50.40 14 143 3.9E-44 T 29-03-2018 CDC59_RS03545 2b934fabf17a9f964b678248b6861b7a 675 SUPERFAMILY SSF52518 358 534 1.82E-64 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CDC59_RS03545 2b934fabf17a9f964b678248b6861b7a 675 SUPERFAMILY SSF52518 15 328 9.9E-122 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CDC59_RS03545 2b934fabf17a9f964b678248b6861b7a 675 SUPERFAMILY SSF52922 542 672 3.8E-44 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CDC59_RS03545 2b934fabf17a9f964b678248b6861b7a 675 Pfam PF02779 Transketolase, pyrimidine binding domain 363 533 8.7E-45 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CDC59_RS03545 2b934fabf17a9f964b678248b6861b7a 675 Gene3D G3DSA:3.40.50.970 1 374 4.4E-124 T 29-03-2018 CDC59_RS03545 2b934fabf17a9f964b678248b6861b7a 675 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 15 343 8.8E-160 T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CDC59_RS03545 2b934fabf17a9f964b678248b6861b7a 675 Gene3D G3DSA:3.40.50.970 375 549 1.0E-39 T 29-03-2018 CDC59_RS03545 2b934fabf17a9f964b678248b6861b7a 675 SMART SM00861 364 534 8.0E-68 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CDC59_RS03545 2b934fabf17a9f964b678248b6861b7a 675 ProSitePatterns PS00801 Transketolase signature 1. 22 42 - T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CDC59_RS03545 2b934fabf17a9f964b678248b6861b7a 675 Pfam PF02780 Transketolase, C-terminal domain 559 663 1.0E-17 T 29-03-2018 IPR033248 Transketolase, C-terminal domain CDC59_RS03545 2b934fabf17a9f964b678248b6861b7a 675 Gene3D G3DSA:3.40.50.920 550 675 4.7E-33 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CDC59_RS03545 2b934fabf17a9f964b678248b6861b7a 675 TIGRFAM TIGR00232 tktlase_bact: transketolase 16 671 8.7E-293 T 29-03-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 CDC59_RS22565 d32b152ae82b5d053381e21524de9fdc 523 Gene3D G3DSA:1.20.1250.20 274 512 4.4E-28 T 29-03-2018 CDC59_RS22565 d32b152ae82b5d053381e21524de9fdc 523 SUPERFAMILY SSF103473 21 217 4.97E-70 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS22565 d32b152ae82b5d053381e21524de9fdc 523 SUPERFAMILY SSF103473 483 506 4.97E-70 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS22565 d32b152ae82b5d053381e21524de9fdc 523 SUPERFAMILY SSF103473 270 441 4.97E-70 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS22565 d32b152ae82b5d053381e21524de9fdc 523 Gene3D G3DSA:1.20.1250.20 33 219 1.3E-32 T 29-03-2018 CDC59_RS22565 d32b152ae82b5d053381e21524de9fdc 523 Pfam PF07690 Major Facilitator Superfamily 39 431 3.2E-53 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDC59_RS22565 d32b152ae82b5d053381e21524de9fdc 523 PRINTS PR01036 Tetracycline resistance protein TetB signature 422 441 5.4E-12 T 29-03-2018 CDC59_RS22565 d32b152ae82b5d053381e21524de9fdc 523 PRINTS PR01036 Tetracycline resistance protein TetB signature 158 182 5.4E-12 T 29-03-2018 CDC59_RS22565 d32b152ae82b5d053381e21524de9fdc 523 PRINTS PR01036 Tetracycline resistance protein TetB signature 224 242 5.4E-12 T 29-03-2018 CDC59_RS22565 d32b152ae82b5d053381e21524de9fdc 523 PRINTS PR01036 Tetracycline resistance protein TetB signature 38 62 5.4E-12 T 29-03-2018 CDC59_RS22565 d32b152ae82b5d053381e21524de9fdc 523 PRINTS PR01036 Tetracycline resistance protein TetB signature 128 148 5.4E-12 T 29-03-2018 CDC59_RS04360 e9aa5b6bd332bd2d625d787adbc3173b 61 Pfam PF04964 Flp/Fap pilin component 12 52 2.1E-12 T 29-03-2018 IPR007047 Flp/Fap pilin component CDC59_RS14275 66d368bca750559a0328d71bc191bba9 647 Pfam PF00350 Dynamin family 58 272 4.4E-14 T 29-03-2018 IPR022812 Dynamin superfamily CDC59_RS14275 66d368bca750559a0328d71bc191bba9 647 Gene3D G3DSA:3.40.50.300 31 445 3.3E-36 T 29-03-2018 CDC59_RS14275 66d368bca750559a0328d71bc191bba9 647 Gene3D G3DSA:3.90.20.10 446 643 3.8E-4 T 29-03-2018 CDC59_RS14275 66d368bca750559a0328d71bc191bba9 647 SUPERFAMILY SSF52540 392 453 6.98E-27 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS14275 66d368bca750559a0328d71bc191bba9 647 SUPERFAMILY SSF52540 181 314 6.98E-27 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS14275 66d368bca750559a0328d71bc191bba9 647 SUPERFAMILY SSF52540 34 119 6.98E-27 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS13550 eda5d6dafd291c0d4cf6d1a0a19550c1 301 Pfam PF07608 Protein of unknown function (DUF1571) 100 301 1.8E-48 T 29-03-2018 IPR011465 Protein of unknown function DUF1571 CDC59_RS01020 0d5336422ef41bea7687f2c0799995d9 167 Pfam PF12306 Inclusion body protein 4 164 9.2E-54 T 29-03-2018 IPR021087 Uncharacterised protein family PixA/AidA CDC59_RS05995 e1a34d2c7df52467f810405ebad06f15 341 Pfam PF02653 Branched-chain amino acid transport system / permease component 53 315 2.0E-35 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CDC59_RS05995 e1a34d2c7df52467f810405ebad06f15 341 Gene3D G3DSA:1.10.3470.10 36 324 9.7E-29 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CDC59_RS13555 774bd83cb75d5787209b52c5e28ceaf2 299 Gene3D G3DSA:2.40.160.20 51 299 1.3E-29 T 29-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CDC59_RS13555 774bd83cb75d5787209b52c5e28ceaf2 299 SUPERFAMILY SSF56925 155 198 1.28E-16 T 29-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CDC59_RS13555 774bd83cb75d5787209b52c5e28ceaf2 299 SUPERFAMILY SSF56925 226 299 1.28E-16 T 29-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CDC59_RS13555 774bd83cb75d5787209b52c5e28ceaf2 299 SUPERFAMILY SSF56925 86 127 1.28E-16 T 29-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CDC59_RS13555 774bd83cb75d5787209b52c5e28ceaf2 299 Pfam PF03922 OmpW family 85 299 5.5E-21 T 29-03-2018 IPR005618 Outer membrane protein, OmpW GO:0019867 CDC59_RS17340 893b6caf73b5ab03d06cd17a59a429f4 633 Pfam PF06276 Ferric iron reductase FhuF-like transporter 439 597 3.0E-18 T 29-03-2018 IPR022770 Ferric iron reductase FhuF domain CDC59_RS17340 893b6caf73b5ab03d06cd17a59a429f4 633 Pfam PF04183 IucA / IucC family 160 400 1.5E-51 T 29-03-2018 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0015343|GO:0019290 CDC59_RS20425 e49833a0bfe7bd63b972029be263728d 224 SUPERFAMILY SSF89562 26 185 3.14E-45 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CDC59_RS20425 e49833a0bfe7bd63b972029be263728d 224 Pfam PF03737 Aldolase/RraA 30 177 1.7E-41 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CDC59_RS20425 e49833a0bfe7bd63b972029be263728d 224 Gene3D G3DSA:3.50.30.40 22 208 4.0E-52 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CDC59_RS06305 8228bc61a2c19bc569d51f1f5e513811 263 Gene3D G3DSA:3.40.50.720 2 260 1.4E-56 T 29-03-2018 CDC59_RS06305 8228bc61a2c19bc569d51f1f5e513811 263 SUPERFAMILY SSF51735 6 258 3.06E-64 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS06305 8228bc61a2c19bc569d51f1f5e513811 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 4.6E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS06305 8228bc61a2c19bc569d51f1f5e513811 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 4.6E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS06305 8228bc61a2c19bc569d51f1f5e513811 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 4.6E-5 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS06305 8228bc61a2c19bc569d51f1f5e513811 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 6.1E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS06305 8228bc61a2c19bc569d51f1f5e513811 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 6.1E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS06305 8228bc61a2c19bc569d51f1f5e513811 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 6.1E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS06305 8228bc61a2c19bc569d51f1f5e513811 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 6.1E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS06305 8228bc61a2c19bc569d51f1f5e513811 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 6.1E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS06305 8228bc61a2c19bc569d51f1f5e513811 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 6.1E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS06305 8228bc61a2c19bc569d51f1f5e513811 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 257 1.1E-40 T 29-03-2018 CDC59_RS00970 ee799a4c024314babf3a0d1522e6e2c1 288 Pfam PF09836 Putative DNA-binding domain 47 114 1.3E-15 T 29-03-2018 IPR018640 Putative DNA-binding domain, bacteria CDC59_RS11825 16a093569d0845de7105414873ad35a5 248 Pfam PF00121 Triosephosphate isomerase 6 245 1.7E-88 T 29-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDC59_RS11825 16a093569d0845de7105414873ad35a5 248 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 4 248 38.524 T 29-03-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDC59_RS11825 16a093569d0845de7105414873ad35a5 248 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 7 240 7.9E-64 T 29-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDC59_RS11825 16a093569d0845de7105414873ad35a5 248 Gene3D G3DSA:3.20.20.70 2 248 6.7E-99 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS11825 16a093569d0845de7105414873ad35a5 248 ProSitePatterns PS00171 Triosephosphate isomerase active site. 165 175 - T 29-03-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDC59_RS11825 16a093569d0845de7105414873ad35a5 248 SUPERFAMILY SSF51351 4 245 7.46E-89 T 29-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CDC59_RS04070 998778288c541c670f023fa366403968 131 SMART SM00363 11 77 3.9E-7 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CDC59_RS04070 998778288c541c670f023fa366403968 131 Gene3D G3DSA:3.10.290.10 4 107 3.1E-25 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CDC59_RS04070 998778288c541c670f023fa366403968 131 Pfam PF01479 S4 domain 11 57 1.2E-12 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CDC59_RS04070 998778288c541c670f023fa366403968 131 PIRSF PIRSF016821 8 131 9.5E-41 T 29-03-2018 IPR025708 Heat shock protein 15 GO:0003677|GO:0003727|GO:0034605|GO:0043023 CDC59_RS04070 998778288c541c670f023fa366403968 131 SUPERFAMILY SSF55174 10 106 2.22E-27 T 29-03-2018 CDC59_RS10755 d3d19fa2babc112aa54ad266f1ca1d97 261 Gene3D G3DSA:3.40.50.720 2 45 2.4E-11 T 29-03-2018 CDC59_RS10755 d3d19fa2babc112aa54ad266f1ca1d97 261 Gene3D G3DSA:3.40.50.720 46 261 9.8E-66 T 29-03-2018 CDC59_RS10755 d3d19fa2babc112aa54ad266f1ca1d97 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 156 184 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CDC59_RS10755 d3d19fa2babc112aa54ad266f1ca1d97 261 SUPERFAMILY SSF51735 5 260 2.98E-79 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS10755 d3d19fa2babc112aa54ad266f1ca1d97 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 260 2.8E-59 T 29-03-2018 CDC59_RS10755 d3d19fa2babc112aa54ad266f1ca1d97 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 157 1.8E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS10755 d3d19fa2babc112aa54ad266f1ca1d97 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 169 188 1.8E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS10755 d3d19fa2babc112aa54ad266f1ca1d97 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 1.8E-11 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS10755 d3d19fa2babc112aa54ad266f1ca1d97 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 159 4.6E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS10755 d3d19fa2babc112aa54ad266f1ca1d97 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 4.6E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS10755 d3d19fa2babc112aa54ad266f1ca1d97 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 224 244 4.6E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS10755 d3d19fa2babc112aa54ad266f1ca1d97 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 190 207 4.6E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS10755 d3d19fa2babc112aa54ad266f1ca1d97 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 4.6E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS10755 d3d19fa2babc112aa54ad266f1ca1d97 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 188 4.6E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS10755 d3d19fa2babc112aa54ad266f1ca1d97 261 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 10 160 0.0046 T 29-03-2018 CDC59_RS01905 b8b13583d9d34b113db5021b204072a7 396 SUPERFAMILY SSF50998 100 330 1.61E-5 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CDC59_RS01905 b8b13583d9d34b113db5021b204072a7 396 Gene3D G3DSA:2.120.10.30 8 328 1.1E-7 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CDC59_RS08545 bd55b6446df664dfcb3072bb23590f65 306 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 11 171 2.2E-33 T 29-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CDC59_RS08545 bd55b6446df664dfcb3072bb23590f65 306 SUPERFAMILY SSF46785 83 158 1.19E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS08545 bd55b6446df664dfcb3072bb23590f65 306 Gene3D G3DSA:1.10.10.10 1 82 1.6E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS08545 bd55b6446df664dfcb3072bb23590f65 306 Pfam PF04079 Segregation and condensation complex subunit ScpB 10 167 8.9E-49 T 29-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CDC59_RS08545 bd55b6446df664dfcb3072bb23590f65 306 SUPERFAMILY SSF46785 1 80 1.77E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS08545 bd55b6446df664dfcb3072bb23590f65 306 Gene3D G3DSA:1.10.10.10 83 175 2.7E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS09520 136f88e519df896f2a93917986e3a3c8 610 Gene3D G3DSA:1.20.58.360 315 542 4.5E-41 T 29-03-2018 CDC59_RS09520 136f88e519df896f2a93917986e3a3c8 610 Pfam PF14496 C-terminal novel E3 ligase, LRR-interacting 238 547 7.4E-33 T 29-03-2018 IPR029487 Novel E3 ligase domain GO:0004842|GO:0016567 CDC59_RS09520 136f88e519df896f2a93917986e3a3c8 610 Gene3D G3DSA:1.20.1270.130 227 313 1.4E-9 T 29-03-2018 CDC59_RS17610 b2fec3b8080533723ad3beb3ba06ecc6 582 Gene3D G3DSA:2.30.38.10 355 453 1.4E-17 T 29-03-2018 CDC59_RS17610 b2fec3b8080533723ad3beb3ba06ecc6 582 Gene3D G3DSA:3.30.300.30 455 580 8.3E-15 T 29-03-2018 CDC59_RS17610 b2fec3b8080533723ad3beb3ba06ecc6 582 SUPERFAMILY SSF56801 10 565 1.07E-110 T 29-03-2018 CDC59_RS17610 b2fec3b8080533723ad3beb3ba06ecc6 582 Gene3D G3DSA:3.40.50.980 6 175 8.5E-38 T 29-03-2018 CDC59_RS17610 b2fec3b8080533723ad3beb3ba06ecc6 582 Gene3D G3DSA:3.40.50.980 176 343 1.9E-37 T 29-03-2018 CDC59_RS17610 b2fec3b8080533723ad3beb3ba06ecc6 582 ProSitePatterns PS00455 Putative AMP-binding domain signature. 170 181 - T 29-03-2018 IPR020845 AMP-binding, conserved site CDC59_RS17610 b2fec3b8080533723ad3beb3ba06ecc6 582 Pfam PF00501 AMP-binding enzyme 20 461 3.8E-85 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CDC59_RS09830 056920217588664740becd803bd811da 267 Pfam PF01026 TatD related DNase 3 263 1.5E-79 T 29-03-2018 IPR001130 TatD family GO:0016788 CDC59_RS09830 056920217588664740becd803bd811da 267 SUPERFAMILY SSF51556 1 263 1.43E-87 T 29-03-2018 IPR032466 Metal-dependent hydrolase CDC59_RS09830 056920217588664740becd803bd811da 267 Gene3D G3DSA:3.20.20.140 1 266 2.4E-84 T 29-03-2018 CDC59_RS09830 056920217588664740becd803bd811da 267 ProSitePatterns PS01090 TatD deoxyribonuclease family signature 2. 134 144 - T 29-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 CDC59_RS09830 056920217588664740becd803bd811da 267 PIRSF PIRSF005902 1 265 2.9E-79 T 29-03-2018 IPR001130 TatD family GO:0016788 CDC59_RS09830 056920217588664740becd803bd811da 267 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 2 10 - T 29-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 CDC59_RS09830 056920217588664740becd803bd811da 267 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 2 263 5.9E-83 T 29-03-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 CDC59_RS21170 16c4ac588bb02fcf8ac1d54622525d0e 458 Pfam PF13520 Amino acid permease 25 434 4.0E-31 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CDC59_RS21170 16c4ac588bb02fcf8ac1d54622525d0e 458 PIRSF PIRSF006060 1 456 1.6E-59 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CDC59_RS20690 33d898c861bacf4ade43301608cc1004 396 Pfam PF07690 Major Facilitator Superfamily 25 323 3.3E-26 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDC59_RS20690 33d898c861bacf4ade43301608cc1004 396 Gene3D G3DSA:1.20.1250.20 13 202 8.4E-21 T 29-03-2018 CDC59_RS20690 33d898c861bacf4ade43301608cc1004 396 Gene3D G3DSA:1.20.1250.20 208 396 3.0E-14 T 29-03-2018 CDC59_RS20690 33d898c861bacf4ade43301608cc1004 396 SUPERFAMILY SSF103473 20 394 1.57E-44 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS06040 b7b03102d31db567127a2175e5bbc319 331 Gene3D G3DSA:3.20.20.80 67 318 8.6E-12 T 29-03-2018 CDC59_RS06040 b7b03102d31db567127a2175e5bbc319 331 SUPERFAMILY SSF51445 73 326 3.31E-21 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CDC59_RS17600 1a4e05620452db1ecd1b14a094739a07 95 Gene3D G3DSA:1.10.1200.10 2 95 3.8E-16 T 29-03-2018 CDC59_RS17600 1a4e05620452db1ecd1b14a094739a07 95 SUPERFAMILY SSF47336 20 94 2.49E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS17600 1a4e05620452db1ecd1b14a094739a07 95 SMART SM01294 26 92 8.1E-4 T 29-03-2018 CDC59_RS17600 1a4e05620452db1ecd1b14a094739a07 95 SMART SM00823 Phosphopantetheine attachment site 25 93 4.2E-13 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CDC59_RS17600 1a4e05620452db1ecd1b14a094739a07 95 Pfam PF00550 Phosphopantetheine attachment site 26 92 9.2E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CDC59_RS02645 debaabd8d87cb8cf7f7d9e3f1f98e8b0 603 SUPERFAMILY SSF161098 317 600 9.35E-39 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS02645 debaabd8d87cb8cf7f7d9e3f1f98e8b0 603 Gene3D G3DSA:1.10.3720.10 320 602 3.3E-33 T 29-03-2018 CDC59_RS02645 debaabd8d87cb8cf7f7d9e3f1f98e8b0 603 Gene3D G3DSA:1.10.3720.10 28 301 2.0E-33 T 29-03-2018 CDC59_RS02645 debaabd8d87cb8cf7f7d9e3f1f98e8b0 603 SUPERFAMILY SSF161098 28 298 1.12E-44 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS02645 debaabd8d87cb8cf7f7d9e3f1f98e8b0 603 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 399 589 2.4E-9 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS02645 debaabd8d87cb8cf7f7d9e3f1f98e8b0 603 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 293 6.9E-13 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS05925 e62a8d09a0187d3c286e4e4b1d3a3426 308 Gene3D G3DSA:3.40.190.10 183 308 1.6E-17 T 29-03-2018 CDC59_RS05925 e62a8d09a0187d3c286e4e4b1d3a3426 308 SMART SM00062 45 279 3.2E-54 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CDC59_RS05925 e62a8d09a0187d3c286e4e4b1d3a3426 308 SUPERFAMILY SSF53850 19 280 2.96E-61 T 29-03-2018 CDC59_RS05925 e62a8d09a0187d3c286e4e4b1d3a3426 308 Gene3D G3DSA:3.40.190.10 9 177 1.8E-31 T 29-03-2018 CDC59_RS05925 e62a8d09a0187d3c286e4e4b1d3a3426 308 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 46 277 4.0E-48 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CDC59_RS07045 dfdfcc621ee6912a8e8991a42ff23b92 290 Gene3D G3DSA:3.40.50.300 12 223 7.6E-31 T 29-03-2018 CDC59_RS07045 dfdfcc621ee6912a8e8991a42ff23b92 290 SMART SM00382 35 193 1.0E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS07045 dfdfcc621ee6912a8e8991a42ff23b92 290 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 39 183 2.8E-13 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CDC59_RS07045 dfdfcc621ee6912a8e8991a42ff23b92 290 SUPERFAMILY SSF52540 17 247 8.77E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS15910 1abc3bef1c738b4c0db4f5fb30315357 139 SUPERFAMILY SSF109635 5 98 4.05E-30 T 29-03-2018 CDC59_RS15910 1abc3bef1c738b4c0db4f5fb30315357 139 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 97 132 4.0E-11 T 29-03-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 CDC59_RS15910 1abc3bef1c738b4c0db4f5fb30315357 139 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 102 126 - T 29-03-2018 IPR020458 Zinc finger, DksA/TraR C4-type conserved site CDC59_RS15910 1abc3bef1c738b4c0db4f5fb30315357 139 Hamap MF_00926 RNA polymerase-binding transcription factor DksA [dksA]. 17 138 28.356 T 29-03-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 CDC59_RS15910 1abc3bef1c738b4c0db4f5fb30315357 139 TIGRFAM TIGR02420 dksA: RNA polymerase-binding protein DksA 21 129 2.8E-43 T 29-03-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 CDC59_RS15910 1abc3bef1c738b4c0db4f5fb30315357 139 SUPERFAMILY SSF57716 99 137 4.85E-8 T 29-03-2018 CDC59_RS22240 a26da89720a19c1cebff84d3777538c9 195 Pfam PF13681 Type IV pilus assembly protein PilX C-term 133 184 5.3E-7 T 29-03-2018 IPR025205 PilX/PilW C-terminal domain CDC59_RS22240 a26da89720a19c1cebff84d3777538c9 195 Pfam PF14341 PilX N-terminal 16 65 1.5E-9 T 29-03-2018 IPR025746 Type 4 fimbrial biogenesis protein PilX, N-terminal domain CDC59_RS17010 1fb7a2630500702b8753dc51db9c4d0e 135 Pfam PF00460 Flagella basal body rod protein 7 37 2.9E-10 T 29-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CDC59_RS17010 1fb7a2630500702b8753dc51db9c4d0e 135 TIGRFAM TIGR01395 FlgC: flagellar basal-body rod protein FlgC 4 135 1.9E-48 T 29-03-2018 IPR006299 Flagellar basal-body rod protein FlgC GO:0030694|GO:0071973 CDC59_RS17010 1fb7a2630500702b8753dc51db9c4d0e 135 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 88 133 1.8E-12 T 29-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CDC59_RS17010 1fb7a2630500702b8753dc51db9c4d0e 135 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 13 33 - T 29-03-2018 IPR019776 Flagellar basal body rod protein, conserved site CDC59_RS04060 4ece1650a8599508aee1edbb0c4c9506 408 Gene3D G3DSA:2.30.40.10 4 78 1.1E-20 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CDC59_RS04060 4ece1650a8599508aee1edbb0c4c9506 408 SUPERFAMILY SSF51556 68 367 3.0E-87 T 29-03-2018 IPR032466 Metal-dependent hydrolase CDC59_RS04060 4ece1650a8599508aee1edbb0c4c9506 408 Pfam PF01979 Amidohydrolase family 66 396 4.9E-18 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CDC59_RS04060 4ece1650a8599508aee1edbb0c4c9506 408 SUPERFAMILY SSF51338 6 68 1.96E-29 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CDC59_RS04060 4ece1650a8599508aee1edbb0c4c9506 408 SUPERFAMILY SSF51338 369 404 1.96E-29 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CDC59_RS04060 4ece1650a8599508aee1edbb0c4c9506 408 Gene3D G3DSA:3.20.20.140 79 367 1.7E-58 T 29-03-2018 CDC59_RS04060 4ece1650a8599508aee1edbb0c4c9506 408 Hamap MF_00372 Imidazolonepropionase [hutI]. 7 407 43.842 T 29-03-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CDC59_RS04060 4ece1650a8599508aee1edbb0c4c9506 408 TIGRFAM TIGR01224 hutI: imidazolonepropionase 29 404 1.4E-141 T 29-03-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CDC59_RS17260 b6a22f3aa1635ff1654362c19d820273 546 Gene3D G3DSA:1.10.357.10 95 271 4.8E-4 T 29-03-2018 CDC59_RS14385 c0d904d884a001139926827356d84a91 268 Gene3D G3DSA:3.40.50.300 1 228 2.6E-58 T 29-03-2018 CDC59_RS14385 c0d904d884a001139926827356d84a91 268 SUPERFAMILY SSF52540 6 227 7.06E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS14385 c0d904d884a001139926827356d84a91 268 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS14385 c0d904d884a001139926827356d84a91 268 Pfam PF00005 ABC transporter 25 167 3.2E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS14385 c0d904d884a001139926827356d84a91 268 SMART SM00382 34 217 1.6E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS14385 c0d904d884a001139926827356d84a91 268 TIGRFAM TIGR01184 ntrCD: nitrate ABC transporter, ATP-binding proteins C and D 25 255 4.9E-102 T 29-03-2018 IPR005890 Nitrate transport ATP-binding subunit C/D GO:0015112|GO:0015706|GO:0016020 CDC59_RS09625 d86cd27a7253b1323b171fc984115f5b 115 Gene3D G3DSA:3.30.1370.10 6 114 0.001 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CDC59_RS20525 5502f18d3e6899f11f46384fed3426de 740 SUPERFAMILY SSF53474 49 382 4.59E-25 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS20525 5502f18d3e6899f11f46384fed3426de 740 Pfam PF11339 Protein of unknown function (DUF3141) 20 605 6.4E-282 T 29-03-2018 IPR024501 Protein of unknown function DUF3141 CDC59_RS20525 5502f18d3e6899f11f46384fed3426de 740 Gene3D G3DSA:3.40.50.1820 32 397 6.6E-15 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS04355 ed6abc097f586407f761c56e69046c07 58 Pfam PF04964 Flp/Fap pilin component 8 52 2.5E-16 T 29-03-2018 IPR007047 Flp/Fap pilin component CDC59_RS02315 cfe3454bdb30e59ace0bdaed79d8c217 118 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 3 118 8.8E-36 T 29-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS02315 cfe3454bdb30e59ace0bdaed79d8c217 118 Gene3D G3DSA:3.30.420.100 1 118 1.2E-34 T 29-03-2018 CDC59_RS02315 cfe3454bdb30e59ace0bdaed79d8c217 118 SUPERFAMILY SSF53137 3 116 5.01E-49 T 29-03-2018 CDC59_RS02315 cfe3454bdb30e59ace0bdaed79d8c217 118 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 1 118 1.6E-36 T 29-03-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CDC59_RS02315 cfe3454bdb30e59ace0bdaed79d8c217 118 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 2 118 25.947 T 29-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CDC59_RS15400 d3aea30f33eb219e9663aa176b1ef071 309 Pfam PF00892 EamA-like transporter family 7 135 3.9E-13 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CDC59_RS15400 d3aea30f33eb219e9663aa176b1ef071 309 Pfam PF00892 EamA-like transporter family 145 275 2.6E-20 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CDC59_RS15400 d3aea30f33eb219e9663aa176b1ef071 309 SUPERFAMILY SSF103481 49 138 4.05E-11 T 29-03-2018 CDC59_RS15400 d3aea30f33eb219e9663aa176b1ef071 309 SUPERFAMILY SSF103481 179 275 2.48E-12 T 29-03-2018 CDC59_RS10525 5c71c2d57b5843eea3d51a14341efb1d 423 SUPERFAMILY SSF51338 361 405 1.11E-14 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CDC59_RS10525 5c71c2d57b5843eea3d51a14341efb1d 423 SUPERFAMILY SSF51338 1 51 1.11E-14 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CDC59_RS10525 5c71c2d57b5843eea3d51a14341efb1d 423 Gene3D G3DSA:3.20.20.140 62 359 1.3E-44 T 29-03-2018 CDC59_RS10525 5c71c2d57b5843eea3d51a14341efb1d 423 Pfam PF07969 Amidohydrolase family 39 399 2.1E-49 T 29-03-2018 IPR013108 Amidohydrolase 3 CDC59_RS10525 5c71c2d57b5843eea3d51a14341efb1d 423 SUPERFAMILY SSF51556 51 370 7.61E-104 T 29-03-2018 IPR032466 Metal-dependent hydrolase CDC59_RS10525 5c71c2d57b5843eea3d51a14341efb1d 423 Gene3D G3DSA:2.30.40.10 1 61 1.9E-12 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CDC59_RS19730 5871ef71061428ad0c3fadcf49ab1eb3 277 PRINTS PR01021 OMPA domain signature 205 220 9.3E-14 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CDC59_RS19730 5871ef71061428ad0c3fadcf49ab1eb3 277 PRINTS PR01021 OMPA domain signature 175 197 9.3E-14 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CDC59_RS19730 5871ef71061428ad0c3fadcf49ab1eb3 277 PRINTS PR01021 OMPA domain signature 220 236 9.3E-14 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CDC59_RS19730 5871ef71061428ad0c3fadcf49ab1eb3 277 SUPERFAMILY SSF103088 166 274 1.96E-34 T 29-03-2018 IPR006665 OmpA-like domain CDC59_RS19730 5871ef71061428ad0c3fadcf49ab1eb3 277 Gene3D G3DSA:3.30.1330.60 106 277 1.7E-38 T 29-03-2018 IPR006665 OmpA-like domain CDC59_RS19730 5871ef71061428ad0c3fadcf49ab1eb3 277 Pfam PF00691 OmpA family 175 269 3.8E-23 T 29-03-2018 IPR006665 OmpA-like domain CDC59_RS22910 67e056bc05649afe7d0dd4345a90b032 398 SUPERFAMILY SSF51905 12 234 1.55E-43 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS22910 67e056bc05649afe7d0dd4345a90b032 398 SUPERFAMILY SSF51905 328 386 1.55E-43 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS22910 67e056bc05649afe7d0dd4345a90b032 398 Pfam PF01266 FAD dependent oxidoreductase 13 367 1.7E-51 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CDC59_RS22910 67e056bc05649afe7d0dd4345a90b032 398 Gene3D G3DSA:3.30.9.10 100 172 2.7E-7 T 29-03-2018 CDC59_RS22910 67e056bc05649afe7d0dd4345a90b032 398 Gene3D G3DSA:3.30.9.10 173 326 1.2E-43 T 29-03-2018 CDC59_RS22910 67e056bc05649afe7d0dd4345a90b032 398 Gene3D G3DSA:3.50.50.60 3 90 5.1E-7 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS07350 c1a5a24331f9dd8ae8099d9340b9026e 91 Gene3D G3DSA:3.40.30.10 1 86 5.7E-7 T 29-03-2018 CDC59_RS07350 c1a5a24331f9dd8ae8099d9340b9026e 91 SUPERFAMILY SSF52833 3 84 3.12E-12 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS07350 c1a5a24331f9dd8ae8099d9340b9026e 91 Pfam PF05768 Glutaredoxin-like domain (DUF836) 3 84 4.0E-17 T 29-03-2018 IPR008554 Glutaredoxin-like CDC59_RS09450 d059861148c04d57a227b11f6aa223e7 411 Pfam PF10009 Uncharacterized protein conserved in bacteria (DUF2252) 15 402 1.3E-90 T 29-03-2018 IPR018721 Protein of unknown function DUF2252 CDC59_RS09450 d059861148c04d57a227b11f6aa223e7 411 SUPERFAMILY SSF56112 18 157 3.06E-5 T 29-03-2018 IPR011009 Protein kinase-like domain CDC59_RS09450 d059861148c04d57a227b11f6aa223e7 411 Gene3D G3DSA:1.10.510.10 3 137 8.1E-6 T 29-03-2018 CDC59_RS14450 5086f725458d7b4e74d12091bcd5d466 70 Pfam PF11174 Protein of unknown function (DUF2970) 14 69 4.7E-26 T 29-03-2018 IPR021344 Protein of unknown function DUF2970 CDC59_RS10385 061e61df06a7af5e067ec9ae5db2afa2 633 Pfam PF02705 K+ potassium transporter 22 554 6.5E-214 T 29-03-2018 IPR003855 Potassium transporter GO:0015079|GO:0016020|GO:0071805 CDC59_RS10385 061e61df06a7af5e067ec9ae5db2afa2 633 Hamap MF_01522 Low affinity potassium transport system protein kup [kup]. 13 633 34.528 T 29-03-2018 IPR023051 Potassium uptake protein, low affinity, Kup CDC59_RS15825 4df6bd138a26440dd44bccff7bda0130 170 PIRSF PIRSF018472 4 164 3.2E-42 T 29-03-2018 IPR026034 Cell shape-determining protein MreD, proteobacterial type CDC59_RS15825 4df6bd138a26440dd44bccff7bda0130 170 Pfam PF04093 rod shape-determining protein MreD 11 149 6.6E-16 T 29-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 CDC59_RS15825 4df6bd138a26440dd44bccff7bda0130 170 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 12 155 2.3E-29 T 29-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 CDC59_RS19290 5fb981bf430e0282f0f120f0f6f57c05 407 Gene3D G3DSA:1.20.1250.20 213 402 1.8E-18 T 29-03-2018 CDC59_RS19290 5fb981bf430e0282f0f120f0f6f57c05 407 SUPERFAMILY SSF103473 19 399 6.28E-37 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS19290 5fb981bf430e0282f0f120f0f6f57c05 407 Pfam PF07690 Major Facilitator Superfamily 43 359 8.1E-17 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDC59_RS19290 5fb981bf430e0282f0f120f0f6f57c05 407 Gene3D G3DSA:1.20.1250.20 19 211 2.6E-11 T 29-03-2018 CDC59_RS08160 70666cdbe36876366b9fa48477ae01c3 431 Pfam PF04551 GcpE protein 34 413 1.2E-112 T 29-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CDC59_RS08160 70666cdbe36876366b9fa48477ae01c3 431 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 23 412 5.7E-119 T 29-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CDC59_RS08160 70666cdbe36876366b9fa48477ae01c3 431 Gene3D G3DSA:3.20.20.70 39 267 3.3E-5 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS08160 70666cdbe36876366b9fa48477ae01c3 431 PIRSF PIRSF004640 16 423 1.5E-127 T 29-03-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CDC59_RS08160 70666cdbe36876366b9fa48477ae01c3 431 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 21 417 28.226 T 29-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CDC59_RS18950 793fb14cc7a7833269b5427ffbb02e8b 664 SUPERFAMILY SSF52743 490 648 6.68E-34 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CDC59_RS18950 793fb14cc7a7833269b5427ffbb02e8b 664 SUPERFAMILY SSF52743 103 327 6.68E-34 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CDC59_RS18950 793fb14cc7a7833269b5427ffbb02e8b 664 Gene3D G3DSA:3.40.50.200 149 655 1.3E-41 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CDC59_RS18950 793fb14cc7a7833269b5427ffbb02e8b 664 Pfam PF00082 Subtilase family 238 636 9.3E-11 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CDC59_RS22540 e8c2f77bb15253a7f33e0eb42c578b94 144 Pfam PF14083 PGDYG protein 40 141 8.6E-52 T 29-03-2018 IPR025688 PGDYG protein CDC59_RS01560 9b304b837fe1d74963110aede0761a0f 199 Pfam PF01569 PAP2 superfamily 57 164 1.0E-13 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CDC59_RS01560 9b304b837fe1d74963110aede0761a0f 199 SUPERFAMILY SSF48317 1 174 5.49E-32 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CDC59_RS01560 9b304b837fe1d74963110aede0761a0f 199 SMART SM00014 56 165 1.8E-11 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CDC59_RS01560 9b304b837fe1d74963110aede0761a0f 199 Gene3D G3DSA:1.20.144.10 4 172 1.1E-17 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CDC59_RS13320 d9b69efd6bef4f6ae4f455e4a82ded20 336 Gene3D G3DSA:3.90.870.10 7 218 1.0E-70 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CDC59_RS13320 d9b69efd6bef4f6ae4f455e4a82ded20 336 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 11 213 2.3E-50 T 29-03-2018 IPR006070 YrdC-like domain GO:0003725 CDC59_RS13320 d9b69efd6bef4f6ae4f455e4a82ded20 336 PIRSF PIRSF004930 1 335 1.2E-100 T 29-03-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 CDC59_RS13320 d9b69efd6bef4f6ae4f455e4a82ded20 336 Pfam PF01300 Telomere recombination 22 203 6.4E-53 T 29-03-2018 IPR006070 YrdC-like domain GO:0003725 CDC59_RS13320 d9b69efd6bef4f6ae4f455e4a82ded20 336 SUPERFAMILY SSF55821 11 213 3.36E-57 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CDC59_RS13320 d9b69efd6bef4f6ae4f455e4a82ded20 336 Pfam PF03481 Putative GTP-binding controlling metal-binding 205 330 1.8E-20 T 29-03-2018 IPR005145 Putative GTP-binding controlling metal-binding domain CDC59_RS14125 1e33c04d78a2eb0939351e16cfbecc8a 273 Gene3D G3DSA:3.40.47.10 9 153 4.0E-8 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS14125 1e33c04d78a2eb0939351e16cfbecc8a 273 Pfam PF13723 Beta-ketoacyl synthase, N-terminal domain 32 224 7.1E-27 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CDC59_RS14125 1e33c04d78a2eb0939351e16cfbecc8a 273 SUPERFAMILY SSF53901 7 154 5.11E-9 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS21095 99932a03b23adfd2bdf160387e711cbc 873 Gene3D G3DSA:3.40.50.720 595 751 0.0012 T 29-03-2018 CDC59_RS21095 99932a03b23adfd2bdf160387e711cbc 873 SUPERFAMILY SSF56059 75 235 1.8E-15 T 29-03-2018 CDC59_RS21095 99932a03b23adfd2bdf160387e711cbc 873 Pfam PF14403 Circularly permuted ATP-grasp type 2 97 496 6.4E-141 T 29-03-2018 IPR025841 Circularly permuted ATP-grasp type 2 CDC59_RS21095 99932a03b23adfd2bdf160387e711cbc 873 Pfam PF04168 A predicted alpha-helical domain with a conserved ER motif. 547 862 1.5E-57 T 29-03-2018 IPR007296 Domain of unknown function DUF403 CDC59_RS14005 26d9d7037292c02f307125dcd1d39626 307 PRINTS PR01320 Inward rectifier K+ channel superfamily signature 282 296 4.9E-15 T 29-03-2018 IPR016449 Potassium channel, inwardly rectifying, Kir GO:0005242|GO:0006813|GO:0016021 CDC59_RS14005 26d9d7037292c02f307125dcd1d39626 307 PRINTS PR01320 Inward rectifier K+ channel superfamily signature 206 224 4.9E-15 T 29-03-2018 IPR016449 Potassium channel, inwardly rectifying, Kir GO:0005242|GO:0006813|GO:0016021 CDC59_RS14005 26d9d7037292c02f307125dcd1d39626 307 PRINTS PR01320 Inward rectifier K+ channel superfamily signature 258 275 4.9E-15 T 29-03-2018 IPR016449 Potassium channel, inwardly rectifying, Kir GO:0005242|GO:0006813|GO:0016021 CDC59_RS14005 26d9d7037292c02f307125dcd1d39626 307 PRINTS PR01320 Inward rectifier K+ channel superfamily signature 86 108 4.9E-15 T 29-03-2018 IPR016449 Potassium channel, inwardly rectifying, Kir GO:0005242|GO:0006813|GO:0016021 CDC59_RS14005 26d9d7037292c02f307125dcd1d39626 307 PRINTS PR01320 Inward rectifier K+ channel superfamily signature 237 257 4.9E-15 T 29-03-2018 IPR016449 Potassium channel, inwardly rectifying, Kir GO:0005242|GO:0006813|GO:0016021 CDC59_RS14005 26d9d7037292c02f307125dcd1d39626 307 SUPERFAMILY SSF81296 118 299 6.06E-60 T 29-03-2018 IPR014756 Immunoglobulin E-set CDC59_RS14005 26d9d7037292c02f307125dcd1d39626 307 Gene3D G3DSA:2.60.40.1400 133 306 4.3E-48 T 29-03-2018 IPR013518 Potassium channel, inwardly rectifying, Kir, cytoplasmic CDC59_RS14005 26d9d7037292c02f307125dcd1d39626 307 Gene3D G3DSA:1.10.287.70 35 132 8.9E-18 T 29-03-2018 CDC59_RS14005 26d9d7037292c02f307125dcd1d39626 307 SUPERFAMILY SSF81324 34 147 2.62E-24 T 29-03-2018 CDC59_RS14005 26d9d7037292c02f307125dcd1d39626 307 Pfam PF01007 Inward rectifier potassium channel 82 299 2.8E-40 T 29-03-2018 IPR016449 Potassium channel, inwardly rectifying, Kir GO:0005242|GO:0006813|GO:0016021 CDC59_RS20210 df0ca89581cca9ab39cdbd7b21304528 128 Pfam PF09487 Bacterial type III secretion protein (HrpB2) 21 128 7.3E-34 T 29-03-2018 IPR013391 Type III secretion protein HrpB2 CDC59_RS20210 df0ca89581cca9ab39cdbd7b21304528 128 TIGRFAM TIGR02558 HrpB2: type III secretion protein HrpB2 9 128 1.3E-47 T 29-03-2018 IPR013391 Type III secretion protein HrpB2 CDC59_RS07800 07e6d3169d3c3f354b2bde81a6333a14 354 Gene3D G3DSA:3.60.21.10 42 288 3.4E-14 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CDC59_RS07800 07e6d3169d3c3f354b2bde81a6333a14 354 SUPERFAMILY SSF56300 44 124 3.29E-11 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CDC59_RS07800 07e6d3169d3c3f354b2bde81a6333a14 354 SUPERFAMILY SSF56300 154 287 3.29E-11 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CDC59_RS14360 d4db9d2ab475f0bcb5292a6c201a5f84 233 Gene3D G3DSA:3.90.850.10 1 233 5.9E-77 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CDC59_RS14360 d4db9d2ab475f0bcb5292a6c201a5f84 233 SUPERFAMILY SSF56529 22 233 1.83E-69 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CDC59_RS14360 d4db9d2ab475f0bcb5292a6c201a5f84 233 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 28 232 4.7E-54 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CDC59_RS14810 bbc18f13082f9c046919c421a4a0ee85 330 Gene3D G3DSA:3.90.850.10 26 316 2.4E-58 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CDC59_RS14810 bbc18f13082f9c046919c421a4a0ee85 330 SUPERFAMILY SSF56529 77 324 1.26E-61 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CDC59_RS14810 bbc18f13082f9c046919c421a4a0ee85 330 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 82 323 2.1E-41 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CDC59_RS02955 e6853e37f5617b2f36c82faf22e5dc50 155 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 28 140 2.1E-26 T 29-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 CDC59_RS02955 e6853e37f5617b2f36c82faf22e5dc50 155 SUPERFAMILY SSF54637 14 146 5.22E-32 T 29-03-2018 IPR029069 HotDog domain CDC59_RS02955 e6853e37f5617b2f36c82faf22e5dc50 155 Pfam PF03061 Thioesterase superfamily 59 133 3.5E-14 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CDC59_RS02955 e6853e37f5617b2f36c82faf22e5dc50 155 TIGRFAM TIGR02286 PaaD: phenylacetic acid degradation protein PaaD 31 141 3.0E-47 T 29-03-2018 IPR011973 Phenylacetic acid degradation protein PaaD GO:0016790 CDC59_RS02955 e6853e37f5617b2f36c82faf22e5dc50 155 Gene3D G3DSA:3.10.129.10 3 144 7.8E-32 T 29-03-2018 CDC59_RS15390 52e9493b621357adec5f1f25b32086b3 426 Gene3D G3DSA:1.20.1250.20 1 200 4.1E-21 T 29-03-2018 CDC59_RS15390 52e9493b621357adec5f1f25b32086b3 426 Gene3D G3DSA:1.20.1250.20 218 420 6.2E-18 T 29-03-2018 CDC59_RS15390 52e9493b621357adec5f1f25b32086b3 426 Pfam PF07690 Major Facilitator Superfamily 19 367 1.1E-23 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDC59_RS15390 52e9493b621357adec5f1f25b32086b3 426 SUPERFAMILY SSF103473 11 414 4.71E-41 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS06225 60103598a8d7f3090b7158638bc718e0 256 SUPERFAMILY SSF53448 4 150 1.41E-26 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDC59_RS06225 60103598a8d7f3090b7158638bc718e0 256 Pfam PF00535 Glycosyl transferase family 2 9 126 5.8E-18 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CDC59_RS06225 60103598a8d7f3090b7158638bc718e0 256 Gene3D G3DSA:3.90.550.10 2 228 2.2E-25 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDC59_RS01875 c3a243081825ac062121059499469678 351 PRINTS PR00111 Alpha/beta hydrolase fold signature 158 171 5.0E-15 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS01875 c3a243081825ac062121059499469678 351 PRINTS PR00111 Alpha/beta hydrolase fold signature 278 292 5.0E-15 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS01875 c3a243081825ac062121059499469678 351 PRINTS PR00111 Alpha/beta hydrolase fold signature 108 123 5.0E-15 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS01875 c3a243081825ac062121059499469678 351 PRINTS PR00111 Alpha/beta hydrolase fold signature 172 185 5.0E-15 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS01875 c3a243081825ac062121059499469678 351 Gene3D G3DSA:3.40.50.1820 51 338 1.7E-46 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS01875 c3a243081825ac062121059499469678 351 Pfam PF00561 alpha/beta hydrolase fold 84 187 3.0E-21 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CDC59_RS01875 c3a243081825ac062121059499469678 351 SUPERFAMILY SSF53474 57 333 1.61E-58 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS18500 4dfa7475865745492090b56e156b05c6 313 SUPERFAMILY SSF103481 61 160 9.15E-13 T 29-03-2018 CDC59_RS18500 4dfa7475865745492090b56e156b05c6 313 SUPERFAMILY SSF103481 213 310 6.67E-11 T 29-03-2018 CDC59_RS18500 4dfa7475865745492090b56e156b05c6 313 Pfam PF00892 EamA-like transporter family 180 307 1.4E-12 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CDC59_RS18500 4dfa7475865745492090b56e156b05c6 313 Pfam PF00892 EamA-like transporter family 29 160 6.0E-15 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CDC59_RS11495 b3b064b32f4efd78c13db679a1a838a5 326 PIRSF PIRSF015582 32 323 9.0E-47 T 29-03-2018 IPR011206 Citrate lyase beta subunit-like CDC59_RS11495 b3b064b32f4efd78c13db679a1a838a5 326 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 46 252 9.3E-13 T 29-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 CDC59_RS11495 b3b064b32f4efd78c13db679a1a838a5 326 SUPERFAMILY SSF51621 32 262 3.09E-41 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CDC59_RS11495 b3b064b32f4efd78c13db679a1a838a5 326 Gene3D G3DSA:3.20.20.60 1 264 2.6E-43 T 29-03-2018 CDC59_RS17605 f23965b5b0602fe96de2d4425d3ef750 578 SUPERFAMILY SSF56645 25 224 1.57E-36 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CDC59_RS17605 f23965b5b0602fe96de2d4425d3ef750 578 Gene3D G3DSA:2.40.110.10 115 212 3.9E-21 T 29-03-2018 CDC59_RS17605 f23965b5b0602fe96de2d4425d3ef750 578 SUPERFAMILY SSF47203 224 372 5.15E-18 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CDC59_RS17605 f23965b5b0602fe96de2d4425d3ef750 578 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 115 211 1.7E-14 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CDC59_RS17605 f23965b5b0602fe96de2d4425d3ef750 578 Gene3D G3DSA:1.20.140.10 213 390 7.0E-24 T 29-03-2018 CDC59_RS17605 f23965b5b0602fe96de2d4425d3ef750 578 Gene3D G3DSA:1.10.540.10 15 114 1.5E-7 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CDC59_RS17605 f23965b5b0602fe96de2d4425d3ef750 578 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 224 370 4.7E-15 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CDC59_RS09060 29b9c839821a7973cd98e0bdfe9d1421 462 SUPERFAMILY SSF56954 7 446 3.92E-46 T 29-03-2018 CDC59_RS09060 29b9c839821a7973cd98e0bdfe9d1421 462 Pfam PF02321 Outer membrane efflux protein 73 245 1.8E-8 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CDC59_RS09060 29b9c839821a7973cd98e0bdfe9d1421 462 Pfam PF02321 Outer membrane efflux protein 276 414 2.2E-7 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CDC59_RS09060 29b9c839821a7973cd98e0bdfe9d1421 462 Gene3D G3DSA:1.20.1600.10 22 450 4.6E-36 T 29-03-2018 CDC59_RS03835 c3e1e71e5041799c84c50b674f7138be 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.3E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS03835 c3e1e71e5041799c84c50b674f7138be 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.3E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS03835 c3e1e71e5041799c84c50b674f7138be 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.3E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS03835 c3e1e71e5041799c84c50b674f7138be 314 Gene3D G3DSA:3.40.190.10 177 274 3.9E-29 T 29-03-2018 CDC59_RS03835 c3e1e71e5041799c84c50b674f7138be 314 Gene3D G3DSA:3.40.190.10 88 176 1.2E-22 T 29-03-2018 CDC59_RS03835 c3e1e71e5041799c84c50b674f7138be 314 SUPERFAMILY SSF53850 88 299 3.19E-42 T 29-03-2018 CDC59_RS03835 c3e1e71e5041799c84c50b674f7138be 314 SUPERFAMILY SSF46785 1 82 3.23E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS03835 c3e1e71e5041799c84c50b674f7138be 314 Gene3D G3DSA:1.10.10.10 1 82 1.0E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS03835 c3e1e71e5041799c84c50b674f7138be 314 Pfam PF03466 LysR substrate binding domain 89 296 5.8E-47 T 29-03-2018 IPR005119 LysR, substrate-binding CDC59_RS03835 c3e1e71e5041799c84c50b674f7138be 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 2.0E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CDC59_RS01345 b5646c4a16c0ae37e0fe45687d70d680 112 Pfam PF07363 Protein of unknown function (DUF1484) 4 111 2.2E-44 T 29-03-2018 IPR009957 Protein of unknown function DUF1484 CDC59_RS18255 c048ffd02be5076532b50b7205c7f1f7 467 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 301 465 1.2E-53 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS18255 c048ffd02be5076532b50b7205c7f1f7 467 SUPERFAMILY SSF55073 310 465 8.63E-49 T 29-03-2018 IPR029787 Nucleotide cyclase CDC59_RS18255 c048ffd02be5076532b50b7205c7f1f7 467 Pfam PF00990 Diguanylate cyclase, GGDEF domain 305 463 2.5E-48 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS18255 c048ffd02be5076532b50b7205c7f1f7 467 SMART SM00267 294 467 5.5E-63 T 29-03-2018 IPR000160 GGDEF domain CDC59_RS18255 c048ffd02be5076532b50b7205c7f1f7 467 Gene3D G3DSA:3.30.70.270 293 467 2.9E-60 T 29-03-2018 CDC59_RS00180 52368a6a190a1d836dbf91e56106c5a1 357 Gene3D G3DSA:1.10.150.20 210 272 2.0E-4 T 29-03-2018 CDC59_RS10955 91a61566bb31bfe236460bd3e12c91be 155 Pfam PF13664 Domain of unknown function (DUF4149) 8 108 8.1E-22 T 29-03-2018 IPR025423 Domain of unknown function DUF4149 CDC59_RS20240 5fa6571a1cebaebf02432e1f7c5f0a21 282 TIGRFAM TIGR01401 fliR_like_III: type III secretion apparatus protein SpaR/YscT/HrcT 17 256 5.7E-66 T 29-03-2018 IPR006304 Type III secretion protein SpaR/YscT GO:0006810|GO:0016021 CDC59_RS20240 5fa6571a1cebaebf02432e1f7c5f0a21 282 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 214 233 1.8E-27 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CDC59_RS20240 5fa6571a1cebaebf02432e1f7c5f0a21 282 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 90 109 1.8E-27 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CDC59_RS20240 5fa6571a1cebaebf02432e1f7c5f0a21 282 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 192 214 1.8E-27 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CDC59_RS20240 5fa6571a1cebaebf02432e1f7c5f0a21 282 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 31 52 1.8E-27 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CDC59_RS20240 5fa6571a1cebaebf02432e1f7c5f0a21 282 Pfam PF01311 Bacterial export proteins, family 1 23 256 2.7E-51 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CDC59_RS12470 6217a01f447d2ad4f7db2ed82ed2668e 257 Pfam PF01925 Sulfite exporter TauE/SafE 7 255 1.4E-42 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CDC59_RS14710 8478d0ffc227eb36bbb7aca590fc131e 700 Pfam PF04185 Phosphoesterase family 48 431 5.9E-112 T 29-03-2018 IPR007312 Phosphoesterase GO:0016788 CDC59_RS14710 8478d0ffc227eb36bbb7aca590fc131e 700 Pfam PF05506 Domain of unknown function (DUF756) 606 685 1.4E-16 T 29-03-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 CDC59_RS14710 8478d0ffc227eb36bbb7aca590fc131e 700 Pfam PF05506 Domain of unknown function (DUF756) 505 591 1.0E-24 T 29-03-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 CDC59_RS14710 8478d0ffc227eb36bbb7aca590fc131e 700 Gene3D G3DSA:3.40.720.10 133 436 3.1E-24 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CDC59_RS14710 8478d0ffc227eb36bbb7aca590fc131e 700 TIGRFAM TIGR03396 PC_PLC: phospholipase C, phosphocholine-specific 5 698 1.1E-259 T 29-03-2018 IPR017767 Bacterial phospholipase C, phosphocholine-specific GO:0034480 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 CDC59_RS03145 26c5b18737f005a7d863ce02a32041da 299 Hamap MF_00911 Cell division protein FtsQ [ftsQ]. 7 247 21.746 T 29-03-2018 IPR026579 Cell division protein FtsQ GO:0090529 CDC59_RS03145 26c5b18737f005a7d863ce02a32041da 299 Pfam PF08478 POTRA domain, FtsQ-type 52 110 7.9E-14 T 29-03-2018 IPR013685 POTRA domain, FtsQ-type CDC59_RS03145 26c5b18737f005a7d863ce02a32041da 299 Gene3D G3DSA:3.40.50.720 21 298 0.0012 T 29-03-2018 CDC59_RS03145 26c5b18737f005a7d863ce02a32041da 299 Pfam PF03799 Cell division protein FtsQ 115 239 2.5E-22 T 29-03-2018 IPR005548 Cell division protein FtsQ/DivIB CDC59_RS14320 1b2b6a716c1d89c49c0d3ad00536e2b9 223 Pfam PF13511 Domain of unknown function (DUF4124) 21 73 2.9E-7 T 29-03-2018 IPR025392 Domain of unknown function DUF4124 CDC59_RS12890 e9579825acb0d50e5fa29ee3cda51e6d 94 SUPERFAMILY SSF47729 3 92 2.06E-30 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CDC59_RS12890 e9579825acb0d50e5fa29ee3cda51e6d 94 Pfam PF00216 Bacterial DNA-binding protein 3 91 1.7E-31 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CDC59_RS12890 e9579825acb0d50e5fa29ee3cda51e6d 94 SMART SM00411 2 91 6.1E-38 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CDC59_RS12890 e9579825acb0d50e5fa29ee3cda51e6d 94 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 47 66 - T 29-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 CDC59_RS12890 e9579825acb0d50e5fa29ee3cda51e6d 94 PRINTS PR01727 Prokaryotic integration host factor signature 75 89 2.7E-14 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CDC59_RS12890 e9579825acb0d50e5fa29ee3cda51e6d 94 PRINTS PR01727 Prokaryotic integration host factor signature 41 56 2.7E-14 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CDC59_RS12890 e9579825acb0d50e5fa29ee3cda51e6d 94 PRINTS PR01727 Prokaryotic integration host factor signature 59 72 2.7E-14 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CDC59_RS12890 e9579825acb0d50e5fa29ee3cda51e6d 94 Gene3D G3DSA:4.10.520.10 1 94 9.9E-33 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CDC59_RS14170 5cd5eadc1bdbe3d40813c7df6d347aef 161 SUPERFAMILY SSF103165 1 161 1.96E-74 T 29-03-2018 IPR007153 Adenosine specific kinase CDC59_RS14170 5cd5eadc1bdbe3d40813c7df6d347aef 161 Gene3D G3DSA:3.40.1520.10 1 160 2.5E-77 T 29-03-2018 IPR007153 Adenosine specific kinase CDC59_RS14170 5cd5eadc1bdbe3d40813c7df6d347aef 161 Pfam PF04008 Adenosine specific kinase 6 160 6.0E-74 T 29-03-2018 IPR007153 Adenosine specific kinase CDC59_RS08790 7d00e85d867b88cbec85a436224f1a31 171 SUPERFAMILY SSF54690 3 149 4.97E-52 T 29-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CDC59_RS08790 7d00e85d867b88cbec85a436224f1a31 171 Gene3D G3DSA:3.90.1170.40 2 149 9.7E-60 T 29-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CDC59_RS08790 7d00e85d867b88cbec85a436224f1a31 171 Pfam PF02391 MoaE protein 7 119 7.5E-37 T 29-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CDC59_RS13960 90ed4a168dcc408b6dcdfe7d98b16f85 348 SUPERFAMILY SSF54427 217 347 1.75E-10 T 29-03-2018 IPR032710 NTF2-like domain CDC59_RS13960 90ed4a168dcc408b6dcdfe7d98b16f85 348 Pfam PF04280 Tim44-like domain 221 346 6.2E-17 T 29-03-2018 IPR007379 Tim44-like domain CDC59_RS13960 90ed4a168dcc408b6dcdfe7d98b16f85 348 SMART SM00978 215 346 6.2E-47 T 29-03-2018 IPR007379 Tim44-like domain CDC59_RS13625 cfcb951ffde01eb3fc0e3be7770eadc1 288 Pfam PF01863 Protein of unknown function DUF45 71 280 2.1E-62 T 29-03-2018 IPR002725 Protein of unknown function DUF45 CDC59_RS22530 69247b842f287f8050581ac6b00c5b50 372 PIRSF PIRSF031982 14 371 4.9E-102 T 29-03-2018 IPR016986 Uncharacterised conserved protein UCP031982, alpha/beta hydrolase, XabL CDC59_RS22530 69247b842f287f8050581ac6b00c5b50 372 SUPERFAMILY SSF53474 52 64 1.61E-29 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS22530 69247b842f287f8050581ac6b00c5b50 372 SUPERFAMILY SSF53474 253 337 1.61E-29 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS22530 69247b842f287f8050581ac6b00c5b50 372 SUPERFAMILY SSF53474 95 198 1.61E-29 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS22530 69247b842f287f8050581ac6b00c5b50 372 Pfam PF03403 Platelet-activating factor acetylhydrolase, isoform II 86 137 2.0E-4 T 29-03-2018 IPR005065 Platelet-activating factor acetylhydrolase-like GO:0003847|GO:0016042 KEGG: 00565+3.1.1.47 CDC59_RS22530 69247b842f287f8050581ac6b00c5b50 372 Gene3D G3DSA:3.40.50.1820 26 371 3.3E-34 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS17905 3c066fee94ef6f33ca27af2482ea4e93 139 Pfam PF12802 MarR family 30 87 5.6E-14 T 29-03-2018 CDC59_RS17905 3c066fee94ef6f33ca27af2482ea4e93 139 SUPERFAMILY SSF46785 3 138 2.87E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS17905 3c066fee94ef6f33ca27af2482ea4e93 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 83 99 3.9E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS17905 3c066fee94ef6f33ca27af2482ea4e93 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 47 63 3.9E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS17905 3c066fee94ef6f33ca27af2482ea4e93 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 64 79 3.9E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS17905 3c066fee94ef6f33ca27af2482ea4e93 139 Gene3D G3DSA:1.10.10.10 1 139 9.4E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS17905 3c066fee94ef6f33ca27af2482ea4e93 139 SMART SM00347 23 123 1.4E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CDC59_RS17905 3c066fee94ef6f33ca27af2482ea4e93 139 ProSitePatterns PS01117 MarR-type HTH domain signature. 62 96 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CDC59_RS16980 dfc86554ff2665941f7e49a8d72e676f 342 Gene3D G3DSA:2.40.160.10 3 342 5.3E-61 T 29-03-2018 CDC59_RS16980 dfc86554ff2665941f7e49a8d72e676f 342 SUPERFAMILY SSF56935 15 342 4.88E-71 T 29-03-2018 CDC59_RS16980 dfc86554ff2665941f7e49a8d72e676f 342 Pfam PF13609 Gram-negative porin 4 324 3.3E-60 T 29-03-2018 CDC59_RS09750 5e0762f5892b2e4c372865a2c2d953fc 282 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 48 228 3.6E-52 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CDC59_RS09750 5e0762f5892b2e4c372865a2c2d953fc 282 Gene3D G3DSA:3.40.225.10 35 276 3.5E-70 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CDC59_RS09750 5e0762f5892b2e4c372865a2c2d953fc 282 SUPERFAMILY SSF53639 42 265 1.06E-70 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CDC59_RS09750 5e0762f5892b2e4c372865a2c2d953fc 282 SMART SM01007 48 228 2.7E-64 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CDC59_RS18790 8bba6521fcc81340252f0a453fe59743 442 PRINTS PR00447 Natural resistance-associated macrophage protein signature 168 189 1.5E-55 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CDC59_RS18790 8bba6521fcc81340252f0a453fe59743 442 PRINTS PR00447 Natural resistance-associated macrophage protein signature 384 403 1.5E-55 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CDC59_RS18790 8bba6521fcc81340252f0a453fe59743 442 PRINTS PR00447 Natural resistance-associated macrophage protein signature 352 369 1.5E-55 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CDC59_RS18790 8bba6521fcc81340252f0a453fe59743 442 PRINTS PR00447 Natural resistance-associated macrophage protein signature 143 162 1.5E-55 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CDC59_RS18790 8bba6521fcc81340252f0a453fe59743 442 PRINTS PR00447 Natural resistance-associated macrophage protein signature 220 243 1.5E-55 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CDC59_RS18790 8bba6521fcc81340252f0a453fe59743 442 PRINTS PR00447 Natural resistance-associated macrophage protein signature 324 343 1.5E-55 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CDC59_RS18790 8bba6521fcc81340252f0a453fe59743 442 PRINTS PR00447 Natural resistance-associated macrophage protein signature 115 141 1.5E-55 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CDC59_RS18790 8bba6521fcc81340252f0a453fe59743 442 Pfam PF01566 Natural resistance-associated macrophage protein 56 414 3.9E-136 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CDC59_RS18790 8bba6521fcc81340252f0a453fe59743 442 Hamap MF_00221 Divalent metal cation transporter MntH [mntH]. 20 440 37.253 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CDC59_RS18790 8bba6521fcc81340252f0a453fe59743 442 TIGRFAM TIGR01197 nramp: metal ion transporter, metal ion (Mn2+/Fe2+) transporter (Nramp) family 34 408 1.1E-111 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CDC59_RS03410 cc32516b241defd2918abe3c0c4e90d3 477 Pfam PF11906 Protein of unknown function (DUF3426) 327 473 5.3E-38 T 29-03-2018 IPR021834 Protein of unknown function DUF3426 CDC59_RS03410 cc32516b241defd2918abe3c0c4e90d3 477 Pfam PF13719 zinc-ribbon domain 9 42 4.1E-13 T 29-03-2018 IPR011723 Zinc finger/thioredoxin putative CDC59_RS03410 cc32516b241defd2918abe3c0c4e90d3 477 TIGRFAM TIGR02098 MJ0042_CXXC: MJ0042 family finger-like domain 8 43 1.0E-16 T 29-03-2018 IPR011723 Zinc finger/thioredoxin putative CDC59_RS18235 660da20676392796d23bc2ead61d518b 145 Pfam PF05232 Chlorhexidine efflux transporter 74 137 2.2E-24 T 29-03-2018 IPR007896 Chlorhexidine efflux transporter CDC59_RS18235 660da20676392796d23bc2ead61d518b 145 Pfam PF05232 Chlorhexidine efflux transporter 7 69 1.1E-22 T 29-03-2018 IPR007896 Chlorhexidine efflux transporter CDC59_RS00900 7bf54a01f4cc42cfc74091faabf58e6f 160 Gene3D G3DSA:3.30.1450.10 37 95 0.044 T 29-03-2018 CDC59_RS02530 452fdfc2f80c1d85ed80d39353a6c423 171 TIGRFAM TIGR04430 OM_asym_MlaD: outer membrane lipid asymmetry maintenance protein MlaD 3 147 2.8E-61 T 29-03-2018 IPR030970 Probable phospholipid ABC transporter-binding protein MlaD GO:0015914 CDC59_RS02530 452fdfc2f80c1d85ed80d39353a6c423 171 Pfam PF02470 MlaD protein 39 116 6.6E-22 T 29-03-2018 IPR003399 Mce/MlaD CDC59_RS22725 ec0e96a9a0af8b5eb4f1e01b5760e5ed 471 SUPERFAMILY SSF103473 52 470 1.05E-44 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS22725 ec0e96a9a0af8b5eb4f1e01b5760e5ed 471 Pfam PF07690 Major Facilitator Superfamily 108 431 8.1E-20 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDC59_RS22725 ec0e96a9a0af8b5eb4f1e01b5760e5ed 471 Gene3D G3DSA:1.20.1250.20 61 274 3.4E-17 T 29-03-2018 CDC59_RS22725 ec0e96a9a0af8b5eb4f1e01b5760e5ed 471 Gene3D G3DSA:1.20.1250.20 284 469 2.3E-10 T 29-03-2018 CDC59_RS21395 24e5c16050d53a8b229c080bc5ae94d2 186 Pfam PF02794 RTX toxin acyltransferase family 23 148 1.2E-42 T 29-03-2018 IPR003996 RTX toxin-activating protein C, bacteria GO:0005737|GO:0009404|GO:0016746 CDC59_RS21395 24e5c16050d53a8b229c080bc5ae94d2 186 PRINTS PR01489 Gram-negative bacterial RTX toxin-activating protein C signature 90 112 9.2E-8 T 29-03-2018 IPR003996 RTX toxin-activating protein C, bacteria GO:0005737|GO:0009404|GO:0016746 CDC59_RS21395 24e5c16050d53a8b229c080bc5ae94d2 186 PRINTS PR01489 Gram-negative bacterial RTX toxin-activating protein C signature 25 41 9.2E-8 T 29-03-2018 IPR003996 RTX toxin-activating protein C, bacteria GO:0005737|GO:0009404|GO:0016746 CDC59_RS08990 45cb9bc2d6072ae29b3d96a892a22954 159 SUPERFAMILY SSF158442 8 153 2.62E-37 T 29-03-2018 IPR023380 Disulphide bond formation protein DsbB-like domain CDC59_RS08990 45cb9bc2d6072ae29b3d96a892a22954 159 Gene3D G3DSA:1.20.1550.10 1 159 4.1E-40 T 29-03-2018 IPR023380 Disulphide bond formation protein DsbB-like domain CDC59_RS08990 45cb9bc2d6072ae29b3d96a892a22954 159 Pfam PF02600 Disulfide bond formation protein DsbB 6 151 3.7E-39 T 29-03-2018 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 CDC59_RS08990 45cb9bc2d6072ae29b3d96a892a22954 159 Hamap MF_00286 Disulfide bond formation protein B [dsbB]. 1 159 20.322 T 29-03-2018 IPR022920 Disulphide bond formation protein DsbB CDC59_RS15065 e6dbf3fc545eacae673f933014edf961 480 SUPERFAMILY SSF160935 36 474 9.42E-99 T 29-03-2018 CDC59_RS15065 e6dbf3fc545eacae673f933014edf961 480 Pfam PF06863 Protein of unknown function (DUF1254) 83 211 7.5E-37 T 29-03-2018 IPR010679 Domain of unknown function DUF1254 CDC59_RS15065 e6dbf3fc545eacae673f933014edf961 480 Pfam PF06742 Protein of unknown function (DUF1214) 354 462 9.8E-24 T 29-03-2018 IPR010621 Domain of unknown function DUF1214 CDC59_RS15065 e6dbf3fc545eacae673f933014edf961 480 Gene3D G3DSA:2.60.40.1610 83 227 1.8E-39 T 29-03-2018 IPR010679 Domain of unknown function DUF1254 CDC59_RS15065 e6dbf3fc545eacae673f933014edf961 480 Gene3D G3DSA:2.60.120.600 301 480 1.6E-34 T 29-03-2018 IPR010621 Domain of unknown function DUF1214 CDC59_RS04195 61a46a98baa0011b73881e1793c58fab 244 Gene3D G3DSA:2.60.120.620 22 244 1.6E-26 T 29-03-2018 CDC59_RS04195 61a46a98baa0011b73881e1793c58fab 244 Pfam PF09859 Oxygenase, catalysing oxidative methylation of damaged DNA 72 243 1.2E-91 T 29-03-2018 IPR018655 Protein of unknown function DUF2086 CDC59_RS15450 cc9de25b263c645513613500b058a8be 166 Pfam PF05360 yiaA/B two helix domain 75 127 3.5E-19 T 29-03-2018 IPR008024 YiaAB two helix CDC59_RS15450 cc9de25b263c645513613500b058a8be 166 Pfam PF05360 yiaA/B two helix domain 12 64 1.1E-21 T 29-03-2018 IPR008024 YiaAB two helix CDC59_RS12240 31232280c38b680b2f2b3a21f328ec00 227 SUPERFAMILY SSF89155 19 225 3.92E-51 T 29-03-2018 IPR020945 DMSO/Nitrate reductase chaperone CDC59_RS12240 31232280c38b680b2f2b3a21f328ec00 227 Pfam PF02613 Nitrate reductase delta subunit 72 194 6.0E-31 T 29-03-2018 IPR020945 DMSO/Nitrate reductase chaperone CDC59_RS12240 31232280c38b680b2f2b3a21f328ec00 227 Gene3D G3DSA:1.10.3480.10 12 227 1.8E-47 T 29-03-2018 IPR020945 DMSO/Nitrate reductase chaperone CDC59_RS03730 880139bc95270d4d1a34a5b104e0029c 383 Gene3D G3DSA:3.20.20.105 1 382 2.7E-150 T 29-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CDC59_RS03730 880139bc95270d4d1a34a5b104e0029c 383 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 4 376 1.1E-156 T 29-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CDC59_RS03730 880139bc95270d4d1a34a5b104e0029c 383 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 4 376 2.7E-150 T 29-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CDC59_RS03730 880139bc95270d4d1a34a5b104e0029c 383 SUPERFAMILY SSF51713 1 376 5.49E-151 T 29-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CDC59_RS03730 880139bc95270d4d1a34a5b104e0029c 383 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 2 377 53.751 T 29-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CDC59_RS03730 880139bc95270d4d1a34a5b104e0029c 383 Pfam PF01702 Queuine tRNA-ribosyltransferase 128 374 3.4E-88 T 29-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CDC59_RS05840 483dfd99378384de0e44fadc7e9799bf 317 Gene3D G3DSA:3.40.50.150 100 315 2.2E-18 T 29-03-2018 CDC59_RS05840 483dfd99378384de0e44fadc7e9799bf 317 SUPERFAMILY SSF53335 115 310 2.21E-18 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS05090 e7b276347d3a42060631bb1b6a59e729 405 Gene3D G3DSA:1.20.1250.20 15 210 7.0E-11 T 29-03-2018 CDC59_RS05090 e7b276347d3a42060631bb1b6a59e729 405 SUPERFAMILY SSF103473 20 401 3.53E-31 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS05090 e7b276347d3a42060631bb1b6a59e729 405 Pfam PF06779 Uncharacterised MFS-type transporter YbfB 32 394 1.3E-121 T 29-03-2018 IPR010645 Uncharacterised MFS-type transporter YbfB CDC59_RS05090 e7b276347d3a42060631bb1b6a59e729 405 Gene3D G3DSA:1.20.1250.20 220 405 2.5E-12 T 29-03-2018 CDC59_RS01780 4255889e4615a30c4d62878435dc62e1 162 Pfam PF14499 Domain of unknown function (DUF4437) 53 138 3.3E-6 T 29-03-2018 IPR028013 Protein of unknown function DUF4437 CDC59_RS01780 4255889e4615a30c4d62878435dc62e1 162 Gene3D G3DSA:2.60.120.10 44 162 1.1E-14 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CDC59_RS01780 4255889e4615a30c4d62878435dc62e1 162 SUPERFAMILY SSF51182 31 159 1.05E-23 T 29-03-2018 IPR011051 RmlC-like cupin domain CDC59_RS11360 8c6465594150f4aa5507cc14b6150b85 162 Pfam PF09361 Phasin protein 6 102 5.4E-18 T 29-03-2018 IPR018968 Phasin CDC59_RS11360 8c6465594150f4aa5507cc14b6150b85 162 TIGRFAM TIGR01841 phasin: phasin family protein 25 111 2.4E-25 T 29-03-2018 IPR010127 Phasin, subfamily 1 CDC59_RS13270 914bdfcd8ecd3196116278cc2fe3b5a7 257 Gene3D G3DSA:3.90.1140.10 41 251 1.5E-14 T 29-03-2018 CDC59_RS13270 914bdfcd8ecd3196116278cc2fe3b5a7 257 Pfam PF06299 Protein of unknown function (DUF1045) 76 235 5.2E-48 T 29-03-2018 IPR009389 Protein of unknown function DUF1045 KEGG: 00030+2.7.4.23|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CDC59_RS11590 bb052e8922ce52a900dc66023780c3d7 136 SUPERFAMILY SSF54593 8 110 5.92E-12 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CDC59_RS11590 bb052e8922ce52a900dc66023780c3d7 136 Gene3D G3DSA:3.10.180.10 5 124 3.3E-12 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CDC59_RS17705 36d39e785e27cb6bf515872a0da694dd 277 SUPERFAMILY SSF52096 8 242 4.32E-68 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CDC59_RS17705 36d39e785e27cb6bf515872a0da694dd 277 Gene3D G3DSA:3.90.226.10 2 275 4.8E-64 T 29-03-2018 CDC59_RS17705 36d39e785e27cb6bf515872a0da694dd 277 Pfam PF00378 Enoyl-CoA hydratase/isomerase 15 264 1.5E-51 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CDC59_RS17705 36d39e785e27cb6bf515872a0da694dd 277 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 110 130 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CDC59_RS09220 dc79d16649217cf5d694b76ef6211520 236 Pfam PF01351 Ribonuclease HII 30 209 6.9E-38 T 29-03-2018 IPR024567 Ribonuclease HII/HIII domain CDC59_RS09220 dc79d16649217cf5d694b76ef6211520 236 SUPERFAMILY SSF53098 27 218 3.03E-68 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDC59_RS09220 dc79d16649217cf5d694b76ef6211520 236 Hamap MF_00052_B Ribonuclease HII [rnhB]. 28 210 36.302 T 29-03-2018 IPR022898 Ribonuclease HII GO:0004523 CDC59_RS09220 dc79d16649217cf5d694b76ef6211520 236 Gene3D G3DSA:3.30.420.10 13 233 1.3E-71 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CDC59_RS23415 a871da8084711d9303ae060d948487df 157 Gene3D G3DSA:1.10.10.10 2 149 2.6E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS23415 a871da8084711d9303ae060d948487df 157 Pfam PF11994 Protein of unknown function (DUF3489) 82 147 3.0E-30 T 29-03-2018 IPR021880 Protein of unknown function DUF3489 CDC59_RS20475 4281e45b9a9eb54d006c10bf3d83c2d2 233 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 44 228 7.7E-18 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS20475 4281e45b9a9eb54d006c10bf3d83c2d2 233 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 17 122 9.7E-16 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CDC59_RS20475 4281e45b9a9eb54d006c10bf3d83c2d2 233 Gene3D G3DSA:1.10.3720.10 3 232 2.2E-37 T 29-03-2018 CDC59_RS20475 4281e45b9a9eb54d006c10bf3d83c2d2 233 SUPERFAMILY SSF161098 17 213 6.41E-36 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS22270 cebda6de6307b4686fc4532d876c7471 482 Gene3D G3DSA:3.90.820.10 1 50 0.029 T 29-03-2018 CDC59_RS22270 cebda6de6307b4686fc4532d876c7471 482 Gene3D G3DSA:3.90.820.10 221 275 4.5E-6 T 29-03-2018 CDC59_RS22270 cebda6de6307b4686fc4532d876c7471 482 Pfam PF13785 Domain of unknown function (DUF4178) 276 408 2.8E-24 T 29-03-2018 IPR025235 Domain of unknown function DUF4178 CDC59_RS22270 cebda6de6307b4686fc4532d876c7471 482 Pfam PF13785 Domain of unknown function (DUF4178) 56 193 2.1E-22 T 29-03-2018 IPR025235 Domain of unknown function DUF4178 CDC59_RS10945 2b34784d1c8115775e4e3838f1d61441 221 Pfam PF01728 FtsJ-like methyltransferase 28 216 4.3E-50 T 29-03-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 CDC59_RS10945 2b34784d1c8115775e4e3838f1d61441 221 Hamap MF_01547 Ribosomal RNA large subunit methyltransferase E [rlmE]. 12 218 30.683 T 29-03-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 KEGG: 00564+2.1.1.16 CDC59_RS10945 2b34784d1c8115775e4e3838f1d61441 221 PIRSF PIRSF005461 1 221 8.8E-67 T 29-03-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 KEGG: 00564+2.1.1.16 CDC59_RS10945 2b34784d1c8115775e4e3838f1d61441 221 Gene3D G3DSA:3.40.50.150 1 221 6.4E-49 T 29-03-2018 CDC59_RS10945 2b34784d1c8115775e4e3838f1d61441 221 SUPERFAMILY SSF53335 27 216 4.38E-35 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS06980 c4de77f967a91faa3ec68c2690070213 396 SUPERFAMILY SSF53383 7 385 5.13E-103 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS06980 c4de77f967a91faa3ec68c2690070213 396 Gene3D G3DSA:3.90.1150.10 264 393 7.6E-32 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS06980 c4de77f967a91faa3ec68c2690070213 396 Pfam PF00155 Aminotransferase class I and II 55 378 1.6E-32 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CDC59_RS06980 c4de77f967a91faa3ec68c2690070213 396 Gene3D G3DSA:3.40.640.10 57 263 1.1E-43 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDC59_RS16050 daa9ab780e49cd5729e6d6cb2fffb24d 106 SUPERFAMILY SSF54909 1 84 1.1E-19 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CDC59_RS16050 daa9ab780e49cd5729e6d6cb2fffb24d 106 Pfam PF03795 YCII-related domain 1 80 1.8E-12 T 29-03-2018 IPR005545 YCII-related CDC59_RS16050 daa9ab780e49cd5729e6d6cb2fffb24d 106 Gene3D G3DSA:3.30.70.1060 1 91 1.1E-15 T 29-03-2018 CDC59_RS07880 81dacce593ac65d6b483e41be744d97c 221 Gene3D G3DSA:1.25.40.10 92 151 2.0E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS07880 81dacce593ac65d6b483e41be744d97c 221 Gene3D G3DSA:1.25.40.10 152 189 0.0014 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS07880 81dacce593ac65d6b483e41be744d97c 221 Gene3D G3DSA:1.25.40.10 36 91 6.7E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS07880 81dacce593ac65d6b483e41be744d97c 221 SUPERFAMILY SSF48452 61 188 3.2E-20 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS07880 81dacce593ac65d6b483e41be744d97c 221 SMART SM00028 85 118 82.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CDC59_RS07880 81dacce593ac65d6b483e41be744d97c 221 SMART SM00028 153 181 50.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CDC59_RS07880 81dacce593ac65d6b483e41be744d97c 221 SMART SM00028 119 152 11.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CDC59_RS09790 6c4a5f16df4d62cdd3272b59fe3055bc 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 25 243 6.7E-42 T 29-03-2018 CDC59_RS09790 6c4a5f16df4d62cdd3272b59fe3055bc 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 20 37 3.3E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS09790 6c4a5f16df4d62cdd3272b59fe3055bc 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 3.3E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS09790 6c4a5f16df4d62cdd3272b59fe3055bc 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 3.3E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS09790 6c4a5f16df4d62cdd3272b59fe3055bc 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 155 3.3E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS09790 6c4a5f16df4d62cdd3272b59fe3055bc 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 184 3.3E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS09790 6c4a5f16df4d62cdd3272b59fe3055bc 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 203 3.3E-28 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS09790 6c4a5f16df4d62cdd3272b59fe3055bc 247 Gene3D G3DSA:3.40.50.720 17 243 6.3E-51 T 29-03-2018 CDC59_RS09790 6c4a5f16df4d62cdd3272b59fe3055bc 247 SUPERFAMILY SSF51735 12 245 6.85E-57 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS13195 18c3afb5760f06e0c03515210e36dbcc 226 SUPERFAMILY SSF159594 35 215 1.39E-23 T 29-03-2018 CDC59_RS13195 18c3afb5760f06e0c03515210e36dbcc 226 Gene3D G3DSA:3.40.50.10610 22 220 3.0E-37 T 29-03-2018 IPR005586 ABC-type transport auxiliary lipoprotein component CDC59_RS13195 18c3afb5760f06e0c03515210e36dbcc 226 Pfam PF03886 ABC-type transport auxiliary lipoprotein component 36 208 2.5E-34 T 29-03-2018 IPR005586 ABC-type transport auxiliary lipoprotein component CDC59_RS01090 3f21b63430cdbda5cd9b97d7185e0579 195 Pfam PF01205 Uncharacterized protein family UPF0029 17 119 2.4E-26 T 29-03-2018 IPR001498 Impact, N-terminal CDC59_RS01090 3f21b63430cdbda5cd9b97d7185e0579 195 Gene3D G3DSA:3.30.70.240 130 193 1.1E-16 T 29-03-2018 CDC59_RS01090 3f21b63430cdbda5cd9b97d7185e0579 195 Gene3D G3DSA:3.30.230.30 2 128 3.0E-39 T 29-03-2018 IPR001498 Impact, N-terminal CDC59_RS01090 3f21b63430cdbda5cd9b97d7185e0579 195 SUPERFAMILY SSF54980 130 193 3.6E-14 T 29-03-2018 IPR035647 EF-G domain III/V-like CDC59_RS01090 3f21b63430cdbda5cd9b97d7185e0579 195 Pfam PF09186 Domain of unknown function (DUF1949) 137 190 2.8E-16 T 29-03-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal CDC59_RS01090 3f21b63430cdbda5cd9b97d7185e0579 195 SUPERFAMILY SSF54211 4 127 2.81E-39 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CDC59_RS14720 66740d9f1307b100e6813ac1cf6aaef8 408 Pfam PF04892 VanZ like family 47 151 2.8E-9 T 29-03-2018 IPR006976 VanZ-like CDC59_RS02630 ff1f7d553d9976c6cc40b1d8877e800b 172 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 21 40 2.1E-14 T 29-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 CDC59_RS02630 ff1f7d553d9976c6cc40b1d8877e800b 172 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 40 58 2.1E-14 T 29-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 CDC59_RS02630 ff1f7d553d9976c6cc40b1d8877e800b 172 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 1 21 2.1E-14 T 29-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 CDC59_RS02630 ff1f7d553d9976c6cc40b1d8877e800b 172 TIGRFAM TIGR01410 tatB: twin arginine-targeting protein translocase TatB 3 74 3.2E-18 T 29-03-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 CDC59_RS02630 ff1f7d553d9976c6cc40b1d8877e800b 172 Pfam PF02416 mttA/Hcf106 family 4 37 1.5E-6 T 29-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 CDC59_RS02630 ff1f7d553d9976c6cc40b1d8877e800b 172 Hamap MF_00237 Sec-independent protein translocase protein TatB [tatB]. 1 142 17.036 T 29-03-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 CDC59_RS10465 9298b407fe9796bb58fa9acaf1bcb72f 324 Pfam PF00850 Histone deacetylase domain 40 285 1.2E-47 T 29-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CDC59_RS10465 9298b407fe9796bb58fa9acaf1bcb72f 324 Gene3D G3DSA:3.40.800.20 3 312 1.2E-61 T 29-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CDC59_RS10465 9298b407fe9796bb58fa9acaf1bcb72f 324 SUPERFAMILY SSF52768 3 284 1.29E-77 T 29-03-2018 CDC59_RS10465 9298b407fe9796bb58fa9acaf1bcb72f 324 PRINTS PR01270 Histone deacetylase superfamily signature 115 138 7.4E-7 T 29-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CDC59_RS10465 9298b407fe9796bb58fa9acaf1bcb72f 324 PRINTS PR01270 Histone deacetylase superfamily signature 227 237 7.4E-7 T 29-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CDC59_RS02700 f621add128c604cbecb1ec4dddc59797 248 SUPERFAMILY SSF46626 189 212 3.06E-53 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS02700 f621add128c604cbecb1ec4dddc59797 248 SUPERFAMILY SSF46626 19 161 3.06E-53 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS02700 f621add128c604cbecb1ec4dddc59797 248 Gene3D G3DSA:1.10.760.10 30 213 1.0E-61 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS02700 f621add128c604cbecb1ec4dddc59797 248 Pfam PF02167 Cytochrome C1 family 37 246 7.4E-22 T 29-03-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 CDC59_RS02700 f621add128c604cbecb1ec4dddc59797 248 Gene3D G3DSA:1.20.5.100 218 247 2.3E-12 T 29-03-2018 CDC59_RS03285 bb7aa22897f684458d81f2ba28c2e648 289 Gene3D G3DSA:2.60.120.620 89 287 6.2E-39 T 29-03-2018 CDC59_RS03285 bb7aa22897f684458d81f2ba28c2e648 289 SMART SM00702 97 281 6.7E-47 T 29-03-2018 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 CDC59_RS03285 bb7aa22897f684458d81f2ba28c2e648 289 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 177 281 9.2E-17 T 29-03-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 CDC59_RS15865 449d4f737e9358049b4b9ee799b4e0c7 232 Gene3D G3DSA:3.30.450.40 36 232 1.5E-12 T 29-03-2018 IPR029016 GAF domain-like CDC59_RS15865 449d4f737e9358049b4b9ee799b4e0c7 232 Pfam PF04340 Protein of unknown function, DUF484 2 230 2.7E-31 T 29-03-2018 IPR007435 Protein of unknown function DUF484 CDC59_RS05965 14c7800e18263db2c3f0687228d865e3 220 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 12 217 9.1E-94 T 29-03-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 CDC59_RS05965 14c7800e18263db2c3f0687228d865e3 220 Pfam PF01144 Coenzyme A transferase 15 205 6.1E-39 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CDC59_RS05965 14c7800e18263db2c3f0687228d865e3 220 Gene3D G3DSA:3.40.1080.10 12 220 2.0E-58 T 29-03-2018 CDC59_RS05965 14c7800e18263db2c3f0687228d865e3 220 SUPERFAMILY SSF100950 12 219 8.37E-69 T 29-03-2018 CDC59_RS05965 14c7800e18263db2c3f0687228d865e3 220 ProSitePatterns PS01274 Coenzyme A transferases signature 2. 53 61 - T 29-03-2018 IPR004164 Coenzyme A transferase active site GO:0008152|GO:0008410 Reactome: R-HSA-77108 CDC59_RS05965 14c7800e18263db2c3f0687228d865e3 220 SMART SM00882 15 212 1.3E-70 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CDC59_RS18695 9f17b8f80c1918b37c9ab0c54d775124 144 SUPERFAMILY SSF54197 4 141 2.78E-43 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 CDC59_RS18695 9f17b8f80c1918b37c9ab0c54d775124 144 Gene3D G3DSA:3.30.428.10 5 141 4.8E-40 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 CDC59_RS18695 9f17b8f80c1918b37c9ab0c54d775124 144 Pfam PF01230 HIT domain 17 113 1.0E-27 T 29-03-2018 IPR001310 Histidine triad (HIT) protein CDC59_RS18695 9f17b8f80c1918b37c9ab0c54d775124 144 PRINTS PR00332 Histidine triad family signature 11 27 2.3E-17 T 29-03-2018 IPR001310 Histidine triad (HIT) protein CDC59_RS18695 9f17b8f80c1918b37c9ab0c54d775124 144 PRINTS PR00332 Histidine triad family signature 32 50 2.3E-17 T 29-03-2018 IPR001310 Histidine triad (HIT) protein CDC59_RS18695 9f17b8f80c1918b37c9ab0c54d775124 144 PRINTS PR00332 Histidine triad family signature 99 109 2.3E-17 T 29-03-2018 IPR001310 Histidine triad (HIT) protein CDC59_RS21185 6f13058a19454d78dc912703f1f9634e 82 Gene3D G3DSA:1.10.10.10 1 82 5.7E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS21185 6f13058a19454d78dc912703f1f9634e 82 SUPERFAMILY SSF46785 13 77 8.19E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS18125 b580078dc461bf6174af1515ba9ec380 341 Gene3D G3DSA:3.50.50.60 1 323 6.0E-20 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS18125 b580078dc461bf6174af1515ba9ec380 341 Pfam PF04820 Tryptophan halogenase 73 330 6.2E-11 T 29-03-2018 IPR006905 Flavin-dependent halogenase CDC59_RS18125 b580078dc461bf6174af1515ba9ec380 341 SUPERFAMILY SSF51905 2 144 9.94E-26 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS18125 b580078dc461bf6174af1515ba9ec380 341 SUPERFAMILY SSF51905 242 320 9.94E-26 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS11740 694edb713699a9a9684b35a2ffaa3275 103 Pfam PF10993 Protein of unknown function (DUF2818) 9 99 1.2E-36 T 29-03-2018 IPR016768 Uncharacterised conserved protein UCP019883, membrane CDC59_RS11740 694edb713699a9a9684b35a2ffaa3275 103 PIRSF PIRSF019883 2 103 8.2E-48 T 29-03-2018 IPR016768 Uncharacterised conserved protein UCP019883, membrane CDC59_RS12420 c01a0c99f4786b3b079c9c522ff9f1a4 372 TIGRFAM TIGR04407 LptF_YjgP: LPS export ABC transporter permease LptF 2 347 1.3E-119 T 29-03-2018 IPR030922 LPS export ABC transporter permease LptF GO:0043190|GO:0055085 CDC59_RS12420 c01a0c99f4786b3b079c9c522ff9f1a4 372 Pfam PF03739 Predicted permease YjgP/YjgQ family 9 346 7.8E-59 T 29-03-2018 IPR005495 Permease LptG/LptF-related GO:0016021 CDC59_RS05360 f39ae5a2d4a1660562aa6bfd9c4a10c2 477 Pfam PF04865 Baseplate J-like protein 190 443 8.6E-41 T 29-03-2018 IPR006949 Baseplate protein J-like CDC59_RS06380 d47eb6669dcfa7b96218c15162af6cf8 353 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 12 333 8.1E-106 T 29-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CDC59_RS06380 d47eb6669dcfa7b96218c15162af6cf8 353 SUPERFAMILY SSF50891 198 314 1.33E-14 T 29-03-2018 IPR029000 Cyclophilin-like domain CDC59_RS06380 d47eb6669dcfa7b96218c15162af6cf8 353 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 35 307 2.7E-94 T 29-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CDC59_RS06380 d47eb6669dcfa7b96218c15162af6cf8 353 SMART SM00797 34 324 7.5E-143 T 29-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CDC59_RS18600 6b3eb2c76cb733c8b898604b460822b8 254 Gene3D G3DSA:3.40.190.10 22 173 4.1E-41 T 29-03-2018 CDC59_RS18600 6b3eb2c76cb733c8b898604b460822b8 254 SUPERFAMILY SSF53850 1 251 5.62E-65 T 29-03-2018 CDC59_RS18600 6b3eb2c76cb733c8b898604b460822b8 254 Gene3D G3DSA:3.40.190.10 174 254 1.8E-14 T 29-03-2018 CDC59_RS18600 6b3eb2c76cb733c8b898604b460822b8 254 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 34 248 2.7E-62 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CDC59_RS18600 6b3eb2c76cb733c8b898604b460822b8 254 SMART SM00062 33 250 6.5E-65 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CDC59_RS18600 6b3eb2c76cb733c8b898604b460822b8 254 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 55 68 - T 29-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 CDC59_RS16245 11573b68eb07507736bfdab40edb16db 183 Gene3D G3DSA:1.10.10.10 15 180 2.6E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS16245 11573b68eb07507736bfdab40edb16db 183 Pfam PF01638 HxlR-like helix-turn-helix 31 120 5.8E-20 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type CDC59_RS16245 11573b68eb07507736bfdab40edb16db 183 SUPERFAMILY SSF46785 20 149 4.23E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS17250 c2045c42a955c4bd82e02fa0c4cc8a72 257 SUPERFAMILY SSF48317 79 248 7.85E-5 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CDC59_RS17250 c2045c42a955c4bd82e02fa0c4cc8a72 257 Pfam PF14378 PAP2 superfamily 90 245 1.7E-12 T 29-03-2018 IPR026841 Inositolphosphotransferase Aur1/Ipt1 CDC59_RS17250 c2045c42a955c4bd82e02fa0c4cc8a72 257 Gene3D G3DSA:1.20.144.10 10 255 2.2E-5 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CDC59_RS16665 701a60260546b3e0b0791bf8dff84cfd 388 Pfam PF15635 GHH signature containing HNH/Endo VII superfamily nuclease toxin 2 269 367 5.0E-15 T 29-03-2018 IPR028917 Tox-GHH2 domain CDC59_RS19645 613ba48e076c4bdea0b8a871a9d874ea 167 Gene3D G3DSA:2.30.110.20 1 163 1.1E-49 T 29-03-2018 IPR008514 Type VI secretion system effector, Hcp CDC59_RS19645 613ba48e076c4bdea0b8a871a9d874ea 167 Pfam PF05638 Type VI secretion system effector, Hcp 5 139 8.4E-39 T 29-03-2018 IPR008514 Type VI secretion system effector, Hcp CDC59_RS19645 613ba48e076c4bdea0b8a871a9d874ea 167 TIGRFAM TIGR03344 VI_effect_Hcp1: type VI secretion system effector, Hcp1 family 15 146 1.2E-24 T 29-03-2018 IPR008514 Type VI secretion system effector, Hcp CDC59_RS19645 613ba48e076c4bdea0b8a871a9d874ea 167 SUPERFAMILY SSF141452 1 162 3.4E-46 T 29-03-2018 IPR008514 Type VI secretion system effector, Hcp CDC59_RS01995 c38784a7fb468b98da9053311bc14ede 421 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 72 399 2.1E-38 T 29-03-2018 CDC59_RS01995 c38784a7fb468b98da9053311bc14ede 421 Gene3D G3DSA:1.50.10.10 25 414 3.4E-28 T 29-03-2018 CDC59_RS01995 c38784a7fb468b98da9053311bc14ede 421 SUPERFAMILY SSF48208 30 403 1.36E-70 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CDC59_RS12555 211db75f9e25f58adee25d2e54574e7d 324 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 17 299 38.567 T 29-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 CDC59_RS12555 211db75f9e25f58adee25d2e54574e7d 324 Gene3D G3DSA:3.40.50.2300 18 305 2.2E-4 T 29-03-2018 CDC59_RS12555 211db75f9e25f58adee25d2e54574e7d 324 Pfam PF02401 LytB protein 19 295 7.7E-94 T 29-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 CDC59_RS12555 211db75f9e25f58adee25d2e54574e7d 324 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 19 297 1.5E-101 T 29-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 CDC59_RS01435 dc7f2ba9e0b735c28422122ae3071841 438 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 139 408 1.3E-56 T 29-03-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 CDC59_RS01435 dc7f2ba9e0b735c28422122ae3071841 438 SUPERFAMILY SSF51445 129 430 1.86E-81 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CDC59_RS01435 dc7f2ba9e0b735c28422122ae3071841 438 Gene3D G3DSA:3.20.20.80 126 437 1.1E-51 T 29-03-2018 CDC59_RS07845 3360049e75a66c7c4e9f761a0760608b 182 Gene3D G3DSA:1.10.260.40 2 63 3.3E-19 T 29-03-2018 CDC59_RS07845 3360049e75a66c7c4e9f761a0760608b 182 SUPERFAMILY SSF47413 4 63 4.02E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDC59_RS07845 3360049e75a66c7c4e9f761a0760608b 182 Gene3D G3DSA:2.60.120.10 64 177 3.7E-15 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CDC59_RS07845 3360049e75a66c7c4e9f761a0760608b 182 Pfam PF01381 Helix-turn-helix 8 59 5.3E-16 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDC59_RS07845 3360049e75a66c7c4e9f761a0760608b 182 Pfam PF07883 Cupin domain 104 173 3.8E-15 T 29-03-2018 IPR013096 Cupin 2, conserved barrel CDC59_RS07845 3360049e75a66c7c4e9f761a0760608b 182 SUPERFAMILY SSF51182 52 177 3.47E-23 T 29-03-2018 IPR011051 RmlC-like cupin domain CDC59_RS07845 3360049e75a66c7c4e9f761a0760608b 182 SMART SM00530 4 59 6.9E-17 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDC59_RS15145 f9cdacccd58541ad4df5b4fdb39a0aaf 329 SUPERFAMILY SSF103481 235 327 1.83E-5 T 29-03-2018 CDC59_RS15145 f9cdacccd58541ad4df5b4fdb39a0aaf 329 Pfam PF00892 EamA-like transporter family 29 161 3.6E-14 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CDC59_RS15145 f9cdacccd58541ad4df5b4fdb39a0aaf 329 SUPERFAMILY SSF103481 68 162 6.8E-8 T 29-03-2018 CDC59_RS03370 22804723bedfada9775f999c969b4a91 359 Pfam PF15984 Bacterial collagen, middle region 88 284 2.6E-58 T 29-03-2018 IPR031929 Bacterial collagen-like protein, middle domain CDC59_RS03370 22804723bedfada9775f999c969b4a91 359 Gene3D G3DSA:1.20.1480.30 56 158 0.0058 T 29-03-2018 CDC59_RS04370 d0b0ac4da462c49d0b28a486ded4eb87 283 Pfam PF04536 TPM domain 41 168 3.9E-34 T 29-03-2018 IPR007621 TPM domain CDC59_RS23115 5ceef6788ed13c0e66fa3f5066672d35 314 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 14 66 2.9E-19 T 29-03-2018 IPR025713 Motility protein B, N-terminal domain CDC59_RS23115 5ceef6788ed13c0e66fa3f5066672d35 314 SUPERFAMILY SSF103088 161 268 1.16E-17 T 29-03-2018 IPR006665 OmpA-like domain CDC59_RS23115 5ceef6788ed13c0e66fa3f5066672d35 314 Pfam PF00691 OmpA family 165 255 2.1E-11 T 29-03-2018 IPR006665 OmpA-like domain CDC59_RS23115 5ceef6788ed13c0e66fa3f5066672d35 314 Gene3D G3DSA:3.30.1330.60 112 300 2.2E-33 T 29-03-2018 IPR006665 OmpA-like domain CDC59_RS04255 250a7de4573feeed082470db8a2ac1ae 107 Pfam PF12112 Protein of unknown function (DUF3579) 5 94 1.9E-38 T 29-03-2018 IPR021969 Protein of unknown function DUF3579 CDC59_RS07125 ef2004f893f220be0595edf6f3dd2a59 350 Gene3D G3DSA:1.10.3470.10 78 336 6.2E-27 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CDC59_RS07125 ef2004f893f220be0595edf6f3dd2a59 350 Pfam PF02653 Branched-chain amino acid transport system / permease component 71 332 2.6E-46 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CDC59_RS19500 991b88645cbb570e0e8a54fa982ef004 177 Pfam PF00583 Acetyltransferase (GNAT) family 21 142 3.1E-7 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CDC59_RS19500 991b88645cbb570e0e8a54fa982ef004 177 Gene3D G3DSA:3.40.630.30 1 170 8.9E-21 T 29-03-2018 CDC59_RS19500 991b88645cbb570e0e8a54fa982ef004 177 SUPERFAMILY SSF55729 1 147 1.13E-21 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDC59_RS20385 a948e5f330f907e6cce0d3de8e73de4b 370 SUPERFAMILY SSF56935 21 370 5.23E-72 T 29-03-2018 CDC59_RS20385 a948e5f330f907e6cce0d3de8e73de4b 370 Pfam PF13609 Gram-negative porin 8 337 2.2E-46 T 29-03-2018 CDC59_RS20385 a948e5f330f907e6cce0d3de8e73de4b 370 Gene3D G3DSA:2.40.160.10 9 370 1.5E-61 T 29-03-2018 CDC59_RS03295 d68ba9d570968733fa5a2849d38453be 182 Gene3D G3DSA:3.40.50.2020 11 182 1.6E-35 T 29-03-2018 CDC59_RS03295 d68ba9d570968733fa5a2849d38453be 182 Pfam PF00156 Phosphoribosyl transferase domain 15 163 1.1E-17 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CDC59_RS03295 d68ba9d570968733fa5a2849d38453be 182 SUPERFAMILY SSF53271 15 180 4.72E-44 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CDC59_RS20720 eab2bbc1681c34282b62187152198f76 389 Gene3D G3DSA:3.40.50.720 10 258 2.1E-63 T 29-03-2018 CDC59_RS20720 eab2bbc1681c34282b62187152198f76 389 Gene3D G3DSA:3.40.250.10 264 386 1.6E-27 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS20720 eab2bbc1681c34282b62187152198f76 389 SMART SM00450 287 384 8.4E-26 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS20720 eab2bbc1681c34282b62187152198f76 389 Pfam PF00899 ThiF family 21 256 8.8E-59 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CDC59_RS20720 eab2bbc1681c34282b62187152198f76 389 Pfam PF00581 Rhodanese-like domain 287 380 4.7E-16 T 29-03-2018 IPR001763 Rhodanese-like domain CDC59_RS20720 eab2bbc1681c34282b62187152198f76 389 SUPERFAMILY SSF69572 7 353 7.32E-90 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CDC59_RS10485 7724ad4a830698b7ea6cdb86eaa6264e 191 Pfam PF00227 Proteasome subunit 2 186 8.6E-10 T 29-03-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 CDC59_RS10485 7724ad4a830698b7ea6cdb86eaa6264e 191 Gene3D G3DSA:3.60.20.10 2 188 1.0E-16 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CDC59_RS10485 7724ad4a830698b7ea6cdb86eaa6264e 191 SUPERFAMILY SSF56235 1 186 5.43E-29 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CDC59_RS01595 4c3c1716fd49a592fa3cdf3d44b3a8e0 266 SUPERFAMILY SSF47240 17 204 1.94E-40 T 29-03-2018 IPR009078 Ferritin-like superfamily CDC59_RS01595 4c3c1716fd49a592fa3cdf3d44b3a8e0 266 Gene3D G3DSA:1.10.620.20 8 229 3.0E-30 T 29-03-2018 CDC59_RS04800 b5a96a88b3b408291eb6d82ba188b1d5 301 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 22 294 1.7E-61 T 29-03-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 CDC59_RS04800 b5a96a88b3b408291eb6d82ba188b1d5 301 SUPERFAMILY SSF51197 27 301 8.7E-81 T 29-03-2018 CDC59_RS04800 b5a96a88b3b408291eb6d82ba188b1d5 301 Gene3D G3DSA:3.60.130.10 15 301 4.7E-67 T 29-03-2018 CDC59_RS05030 e4574a1b244450862ef0f8c6c3f251d7 150 Pfam PF09980 Predicted membrane protein (DUF2214) 4 149 7.5E-55 T 29-03-2018 IPR018706 Protein of unknown function DUF2214, membrane CDC59_RS09730 8024dec4287fd6519b2f0d3ddef3232a 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 258 6.9E-56 T 29-03-2018 CDC59_RS09730 8024dec4287fd6519b2f0d3ddef3232a 260 Gene3D G3DSA:3.40.50.720 51 260 4.8E-58 T 29-03-2018 CDC59_RS09730 8024dec4287fd6519b2f0d3ddef3232a 260 Gene3D G3DSA:3.40.50.720 5 50 6.8E-12 T 29-03-2018 CDC59_RS09730 8024dec4287fd6519b2f0d3ddef3232a 260 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 13 197 3.9E-4 T 29-03-2018 CDC59_RS09730 8024dec4287fd6519b2f0d3ddef3232a 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 153 181 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CDC59_RS09730 8024dec4287fd6519b2f0d3ddef3232a 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 1.4E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS09730 8024dec4287fd6519b2f0d3ddef3232a 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 136 152 1.4E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS09730 8024dec4287fd6519b2f0d3ddef3232a 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 204 1.4E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS09730 8024dec4287fd6519b2f0d3ddef3232a 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 185 1.4E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS09730 8024dec4287fd6519b2f0d3ddef3232a 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 1.4E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS09730 8024dec4287fd6519b2f0d3ddef3232a 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 1.4E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS09730 8024dec4287fd6519b2f0d3ddef3232a 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 150 6.0E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS09730 8024dec4287fd6519b2f0d3ddef3232a 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 6.0E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS09730 8024dec4287fd6519b2f0d3ddef3232a 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 166 185 6.0E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS09730 8024dec4287fd6519b2f0d3ddef3232a 260 SUPERFAMILY SSF51735 7 259 1.93E-76 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS05180 64d19e50f2214f2ebba1252477ce6df1 558 TIGRFAM TIGR01630 psiM2_ORF9: phage uncharacterized protein, C-terminal domain 394 527 4.6E-18 T 29-03-2018 IPR006517 Archaeophage PsiM2, terminase large subunit CDC59_RS12120 8348830d0e0a72685e68f4d7e45aefee 252 Gene3D G3DSA:3.40.50.720 1 42 1.2E-10 T 29-03-2018 CDC59_RS12120 8348830d0e0a72685e68f4d7e45aefee 252 Gene3D G3DSA:3.40.50.720 43 252 1.9E-67 T 29-03-2018 CDC59_RS12120 8348830d0e0a72685e68f4d7e45aefee 252 SUPERFAMILY SSF51735 5 251 5.08E-83 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS12120 8348830d0e0a72685e68f4d7e45aefee 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 249 1.4E-65 T 29-03-2018 CDC59_RS12120 8348830d0e0a72685e68f4d7e45aefee 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 3.1E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS12120 8348830d0e0a72685e68f4d7e45aefee 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 3.1E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS12120 8348830d0e0a72685e68f4d7e45aefee 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 3.1E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS12120 8348830d0e0a72685e68f4d7e45aefee 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.2E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS12120 8348830d0e0a72685e68f4d7e45aefee 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 1.2E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS12120 8348830d0e0a72685e68f4d7e45aefee 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.2E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS12120 8348830d0e0a72685e68f4d7e45aefee 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.2E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS12120 8348830d0e0a72685e68f4d7e45aefee 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.2E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS12120 8348830d0e0a72685e68f4d7e45aefee 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.2E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CDC59_RS21370 af51245bb71442fefcd42ef47a778596 107 SUPERFAMILY SSF160424 7 107 2.22E-12 T 29-03-2018 IPR006728 Protein of unknown function DUF600 CDC59_RS21370 af51245bb71442fefcd42ef47a778596 107 Gene3D G3DSA:3.30.500.20 2 107 1.6E-16 T 29-03-2018 CDC59_RS13315 c9459b060c3a5b0ccb4d3299ae0467f6 347 Pfam PF00657 GDSL-like Lipase/Acylhydrolase 41 334 1.7E-10 T 29-03-2018 IPR001087 GDSL lipase/esterase GO:0016788 CDC59_RS13315 c9459b060c3a5b0ccb4d3299ae0467f6 347 Gene3D G3DSA:3.40.50.1110 24 346 1.7E-53 T 29-03-2018 CDC59_RS13315 c9459b060c3a5b0ccb4d3299ae0467f6 347 SUPERFAMILY SSF52266 312 340 2.75E-19 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain CDC59_RS13315 c9459b060c3a5b0ccb4d3299ae0467f6 347 SUPERFAMILY SSF52266 38 270 2.75E-19 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain CDC59_RS22145 42d3f640b57a855605a2006627f14912 242 Pfam PF01872 RibD C-terminal domain 4 187 2.4E-29 T 29-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CDC59_RS22145 42d3f640b57a855605a2006627f14912 242 SUPERFAMILY SSF53597 3 217 7.4E-33 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CDC59_RS22145 42d3f640b57a855605a2006627f14912 242 Gene3D G3DSA:3.40.430.10 1 229 9.7E-41 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CDC59_RS20600 277a0472bafbea8aa471f0c7cfe4fa5b 114 Pfam PF10734 Protein of unknown function (DUF2523) 69 106 2.4E-8 T 29-03-2018 IPR019670 Protein of unkown function DUF2523 CDC59_RS17150 d2f7e02587ee92cb58d460db8cda990a 118 Pfam PF05400 Flagellar protein FliT 27 112 2.1E-21 T 29-03-2018 IPR008622 Flagellar protein FliT CDC59_RS17150 d2f7e02587ee92cb58d460db8cda990a 118 Gene3D G3DSA:1.20.58.380 11 96 7.9E-24 T 29-03-2018 CDC59_RS04230 e3b969656696478d2e4e7f9770c5a747 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 61 3.2E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDC59_RS04230 e3b969656696478d2e4e7f9770c5a747 211 SUPERFAMILY SSF46689 7 75 1.33E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS04230 e3b969656696478d2e4e7f9770c5a747 211 Gene3D G3DSA:1.10.357.10 9 194 7.7E-23 T 29-03-2018 CDC59_RS05790 866cba5a391aa737014a7993ef360943 89 Pfam PF03235 Protein of unknown function DUF262 13 77 1.2E-18 T 29-03-2018 IPR004919 Domain of unknown function DUF262 CDC59_RS03800 3986f60ede5fec3132ee9a8a75d57d12 442 ProSitePatterns PS00217 Sugar transport proteins signature 2. 115 140 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CDC59_RS03800 3986f60ede5fec3132ee9a8a75d57d12 442 SUPERFAMILY SSF103473 10 436 3.14E-71 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS03800 3986f60ede5fec3132ee9a8a75d57d12 442 Gene3D G3DSA:1.20.1250.20 18 212 2.0E-32 T 29-03-2018 CDC59_RS03800 3986f60ede5fec3132ee9a8a75d57d12 442 Pfam PF00083 Sugar (and other) transporter 51 438 8.0E-54 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CDC59_RS03800 3986f60ede5fec3132ee9a8a75d57d12 442 Gene3D G3DSA:1.20.1250.20 226 441 2.1E-27 T 29-03-2018 CDC59_RS05600 a9fc0a02e74cad49d9212ade1e7c03bf 374 Pfam PF10544 T5orf172 domain 245 352 9.2E-10 T 29-03-2018 IPR018306 Bacteriophage T5, Orf172 DNA-binding CDC59_RS05600 a9fc0a02e74cad49d9212ade1e7c03bf 374 SMART SM00974 260 354 2.0E-17 T 29-03-2018 IPR018306 Bacteriophage T5, Orf172 DNA-binding CDC59_RS14070 b128e0ae2be5ad8f18191ea980cfcd4b 137 Pfam PF04143 Sulphur transport 47 131 1.9E-6 T 29-03-2018 IPR007272 Sulphur transport domain CDC59_RS00015 fc1d28cc63f2cdc1a8d7e3f7b810e5b0 104 SMART SM01234 1 68 1.1E-37 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CDC59_RS00015 fc1d28cc63f2cdc1a8d7e3f7b810e5b0 104 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 5 71 3.9E-26 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CDC59_RS00015 fc1d28cc63f2cdc1a8d7e3f7b810e5b0 104 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 1 69 23.101 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CDC59_RS00015 fc1d28cc63f2cdc1a8d7e3f7b810e5b0 104 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 17 68 1.0E-23 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CDC59_RS00015 fc1d28cc63f2cdc1a8d7e3f7b810e5b0 104 Pfam PF01809 Haemolytic domain 3 68 5.5E-26 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CDC59_RS05795 759d750846d66f29e337437af144c192 193 Gene3D G3DSA:3.40.50.360 1 193 1.8E-25 T 29-03-2018 IPR029039 Flavoprotein-like domain CDC59_RS05795 759d750846d66f29e337437af144c192 193 SUPERFAMILY SSF52218 1 192 4.63E-32 T 29-03-2018 IPR029039 Flavoprotein-like domain CDC59_RS05795 759d750846d66f29e337437af144c192 193 Pfam PF02525 Flavodoxin-like fold 2 187 4.3E-27 T 29-03-2018 IPR003680 Flavodoxin-like fold CDC59_RS00920 2b5ac5a8da8d94659290e2b28e5ef699 158 SUPERFAMILY SSF51182 57 149 6.55E-18 T 29-03-2018 IPR011051 RmlC-like cupin domain CDC59_RS00920 2b5ac5a8da8d94659290e2b28e5ef699 158 Pfam PF07883 Cupin domain 79 138 1.1E-13 T 29-03-2018 IPR013096 Cupin 2, conserved barrel CDC59_RS00920 2b5ac5a8da8d94659290e2b28e5ef699 158 Gene3D G3DSA:2.60.120.10 67 158 5.9E-15 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CDC59_RS11930 1ba0d260f7dd65647ec43a1a8d1af8b6 232 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 8.7E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDC59_RS11930 1ba0d260f7dd65647ec43a1a8d1af8b6 232 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 8.7E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDC59_RS11930 1ba0d260f7dd65647ec43a1a8d1af8b6 232 Pfam PF13972 Bacterial transcriptional repressor 67 213 1.0E-43 T 29-03-2018 IPR025722 Bacterial transcriptional repressor TetR CDC59_RS11930 1ba0d260f7dd65647ec43a1a8d1af8b6 232 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 62 1.4E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CDC59_RS11930 1ba0d260f7dd65647ec43a1a8d1af8b6 232 Gene3D G3DSA:1.10.357.10 10 224 1.2E-26 T 29-03-2018 CDC59_RS11930 1ba0d260f7dd65647ec43a1a8d1af8b6 232 SUPERFAMILY SSF46689 8 78 1.23E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CDC59_RS14570 11bc7b41ebccf2827ff41d6b9b98eb59 270 Pfam PF09694 Bacterial protein of unknown function (Gcw_chp) 37 269 1.4E-65 T 29-03-2018 IPR010239 Conserved hypothetical protein CHP02001 CDC59_RS14570 11bc7b41ebccf2827ff41d6b9b98eb59 270 TIGRFAM TIGR02001 gcw_chp: conserved hypothetical protein 14 269 6.1E-79 T 29-03-2018 IPR010239 Conserved hypothetical protein CHP02001 CDC59_RS02170 e8b650f62f91bea9cc1cb2f611a1dccf 613 Pfam PF09909 Uncharacterized protein conserved in bacteria (DUF2138) 6 571 1.7E-223 T 29-03-2018 IPR018671 Protein of unknown function DUF2138 CDC59_RS18380 7127d59276ea9fce5cf6f878f2c8e384 403 Pfam PF05940 NnrS protein 25 397 1.0E-99 T 29-03-2018 IPR010266 NnrS CDC59_RS17450 7c8f07f444a735bc57a05db92813cdb3 153 Pfam PF09828 Chromate resistance exported protein 3 137 4.6E-49 T 29-03-2018 IPR018634 Chromate resistance exported protein CDC59_RS21775 186c3f442ce01f81aabebc279eb6b3f8 93 Pfam PF11373 Protein of unknown function (DUF3175) 1 81 1.1E-37 T 29-03-2018 IPR021513 Ralstonia phage RSL1, Orf186 CDC59_RS04585 b396f1276d7e213a3a58d1ef6351b1db 249 SUPERFAMILY SSF56317 4 234 1.44E-44 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CDC59_RS04585 b396f1276d7e213a3a58d1ef6351b1db 249 Pfam PF00795 Carbon-nitrogen hydrolase 7 234 3.3E-24 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CDC59_RS04585 b396f1276d7e213a3a58d1ef6351b1db 249 Gene3D G3DSA:3.60.110.10 1 236 5.4E-42 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CDC59_RS12180 bb194df397d83c14b9160b6903044481 239 Pfam PF10099 Anti-sigma-K factor rskA 77 232 8.0E-26 T 29-03-2018 IPR018764 Anti-sigma K factor RskA GO:0005886|GO:0016021 CDC59_RS21025 8c9c73682ce7a873eb631f749eee2d9b 491 Gene3D G3DSA:3.40.309.10 272 469 3.0E-61 T 29-03-2018 CDC59_RS21025 8c9c73682ce7a873eb631f749eee2d9b 491 Gene3D G3DSA:3.40.605.10 2 271 1.7E-87 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CDC59_RS21025 8c9c73682ce7a873eb631f749eee2d9b 491 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 255 262 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CDC59_RS21025 8c9c73682ce7a873eb631f749eee2d9b 491 SUPERFAMILY SSF53720 8 486 1.7E-150 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CDC59_RS21025 8c9c73682ce7a873eb631f749eee2d9b 491 Pfam PF00171 Aldehyde dehydrogenase family 23 483 2.6E-146 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CDC59_RS14865 383226cfe4679da7058281a1e41bbd93 46 Pfam PF08085 Entericidin EcnA/B family 19 39 2.9E-10 T 29-03-2018 IPR012556 Entericidin A/B GO:0009636|GO:0016020 CDC59_RS15750 2b55711f0c38e29cfa8c811f13b4588c 263 Pfam PF14334 Domain of unknown function (DUF4390) 40 196 2.4E-59 T 29-03-2018 IPR025500 Protein of unknown function DUF4390 CDC59_RS02635 9e9d2737ee201032a3610c8495883edb 265 Pfam PF00902 Sec-independent protein translocase protein (TatC) 23 233 4.1E-68 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CDC59_RS02635 9e9d2737ee201032a3610c8495883edb 265 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 19 46 1.6E-44 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CDC59_RS02635 9e9d2737ee201032a3610c8495883edb 265 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 96 114 1.6E-44 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CDC59_RS02635 9e9d2737ee201032a3610c8495883edb 265 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 114 140 1.6E-44 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CDC59_RS02635 9e9d2737ee201032a3610c8495883edb 265 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 166 194 1.6E-44 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CDC59_RS02635 9e9d2737ee201032a3610c8495883edb 265 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 21 238 5.8E-67 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CDC59_RS02635 9e9d2737ee201032a3610c8495883edb 265 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 12 252 18.399 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CDC59_RS05570 4e67848fbb758ebba7f03ea019f3925b 118 SUPERFAMILY SSF47413 12 76 2.95E-16 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDC59_RS05570 4e67848fbb758ebba7f03ea019f3925b 118 SMART SM00530 18 73 2.9E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDC59_RS05570 4e67848fbb758ebba7f03ea019f3925b 118 Gene3D G3DSA:1.10.260.40 2 91 4.4E-19 T 29-03-2018 CDC59_RS05570 4e67848fbb758ebba7f03ea019f3925b 118 Pfam PF01381 Helix-turn-helix 19 73 7.4E-16 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDC59_RS19955 5f7ec14e202f34dfeee3bada70391387 501 SUPERFAMILY SSF56954 2 30 2.88E-116 T 29-03-2018 CDC59_RS19955 5f7ec14e202f34dfeee3bada70391387 501 SUPERFAMILY SSF56954 69 486 2.88E-116 T 29-03-2018 CDC59_RS19955 5f7ec14e202f34dfeee3bada70391387 501 Pfam PF02321 Outer membrane efflux protein 78 268 4.1E-23 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CDC59_RS19955 5f7ec14e202f34dfeee3bada70391387 501 Pfam PF02321 Outer membrane efflux protein 302 481 1.3E-31 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CDC59_RS19955 5f7ec14e202f34dfeee3bada70391387 501 Gene3D G3DSA:1.20.1600.10 18 489 5.5E-107 T 29-03-2018 CDC59_RS19955 5f7ec14e202f34dfeee3bada70391387 501 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 10 483 2.4E-128 T 29-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 CDC59_RS04240 afd692132fc840715cab2ef0ecd781a7 281 Gene3D G3DSA:1.25.40.10 16 280 9.4E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS04240 afd692132fc840715cab2ef0ecd781a7 281 Pfam PF13371 Tetratricopeptide repeat 199 270 3.6E-23 T 29-03-2018 CDC59_RS04240 afd692132fc840715cab2ef0ecd781a7 281 Pfam PF13369 Transglutaminase-like superfamily 42 197 3.1E-47 T 29-03-2018 IPR032698 Protein SirB1, N-terminal Reactome: R-HSA-8951664|Reactome: R-HSA-983168 CDC59_RS19440 394745dce0be871fac75b5e1461a9208 69 Pfam PF10932 Protein of unknown function (DUF2783) 3 60 4.9E-32 T 29-03-2018 IPR021233 Protein of unknown function DUF2783 CDC59_RS04030 51141df2e4267e08cc89263dadca3347 309 Gene3D G3DSA:2.60.200.30 155 276 6.0E-40 T 29-03-2018 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CDC59_RS04030 51141df2e4267e08cc89263dadca3347 309 SUPERFAMILY SSF111331 20 301 4.58E-87 T 29-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CDC59_RS04030 51141df2e4267e08cc89263dadca3347 309 Pfam PF01513 ATP-NAD kinase 73 282 1.9E-57 T 29-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CDC59_RS04030 51141df2e4267e08cc89263dadca3347 309 Hamap MF_00361 NAD kinase [nadK]. 19 299 32.38 T 29-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CDC59_RS04030 51141df2e4267e08cc89263dadca3347 309 Gene3D G3DSA:3.40.50.10330 14 154 1.5E-35 T 29-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CDC59_RS18730 2b4ec1f424b32e3a9d2d487f3d383e3d 419 Gene3D G3DSA:3.40.50.2000 214 357 1.4E-38 T 29-03-2018 CDC59_RS18730 2b4ec1f424b32e3a9d2d487f3d383e3d 419 Gene3D G3DSA:3.40.50.2000 2 213 3.5E-75 T 29-03-2018 CDC59_RS18730 2b4ec1f424b32e3a9d2d487f3d383e3d 419 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 3 372 8.8E-152 T 29-03-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 CDC59_RS18730 2b4ec1f424b32e3a9d2d487f3d383e3d 419 SUPERFAMILY SSF53756 1 372 2.61E-134 T 29-03-2018 CDC59_RS18730 2b4ec1f424b32e3a9d2d487f3d383e3d 419 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 22 371 6.6E-121 T 29-03-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001 CDC59_RS20895 af9d579f08fb0feb7d547978cc4878f7 207 Pfam PF01810 LysE type translocator 17 195 8.6E-16 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CDC59_RS16485 0a60c6341ce39c4e59b52a130af16464 361 Pfam PF04632 Fusaric acid resistance protein family 37 285 3.4E-12 T 29-03-2018 IPR006726 Para-hydroxybenzoic acid efflux pump subunit AaeB/fusaric acid resistance protein GO:0005886|GO:0006810 CDC59_RS09985 48472e051fa540853cc296c6f8037e61 440 Pfam PF02653 Branched-chain amino acid transport system / permease component 53 328 2.8E-30 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CDC59_RS09985 48472e051fa540853cc296c6f8037e61 440 Gene3D G3DSA:1.10.3470.10 19 342 6.7E-27 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CDC59_RS13120 e1260364da6e1fc0164fb9e79e996af6 305 Gene3D G3DSA:2.40.160.40 153 298 4.3E-4 T 29-03-2018 CDC59_RS04480 b925304e0166d3a9aace54548a11beaf 183 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 8 182 2.0E-87 T 29-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CDC59_RS04480 b925304e0166d3a9aace54548a11beaf 183 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 8 177 3.5E-75 T 29-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CDC59_RS04480 b925304e0166d3a9aace54548a11beaf 183 SUPERFAMILY SSF51182 2 180 5.1E-78 T 29-03-2018 IPR011051 RmlC-like cupin domain CDC59_RS04480 b925304e0166d3a9aace54548a11beaf 183 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 4 178 1.1E-84 T 29-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CDC59_RS04480 b925304e0166d3a9aace54548a11beaf 183 Gene3D G3DSA:2.60.120.10 1 181 5.3E-77 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CDC59_RS03280 404f3be2def886aa70c255ccf2deeb59 244 Pfam PF01464 Transglycosylase SLT domain 97 188 1.0E-17 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 CDC59_RS03280 404f3be2def886aa70c255ccf2deeb59 244 SUPERFAMILY SSF53955 89 205 3.44E-29 T 29-03-2018 IPR023346 Lysozyme-like domain CDC59_RS03280 404f3be2def886aa70c255ccf2deeb59 244 Gene3D G3DSA:1.10.530.10 22 219 1.9E-26 T 29-03-2018 CDC59_RS10035 654ed11ea239d1afe6d445c5fba6ed2b 305 Gene3D G3DSA:1.10.3470.10 1 289 3.8E-37 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CDC59_RS10035 654ed11ea239d1afe6d445c5fba6ed2b 305 Pfam PF02653 Branched-chain amino acid transport system / permease component 9 280 1.2E-33 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CDC59_RS20035 057e1664d99b6b4ed18f8e8b072f150d 284 SUPERFAMILY SSF63829 3 277 2.94E-64 T 29-03-2018 CDC59_RS20035 057e1664d99b6b4ed18f8e8b072f150d 284 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 153 173 8.6E-30 T 29-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) CDC59_RS20035 057e1664d99b6b4ed18f8e8b072f150d 284 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 195 212 8.6E-30 T 29-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) CDC59_RS20035 057e1664d99b6b4ed18f8e8b072f150d 284 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 6 23 8.6E-30 T 29-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) CDC59_RS20035 057e1664d99b6b4ed18f8e8b072f150d 284 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 237 255 8.6E-30 T 29-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) CDC59_RS20035 057e1664d99b6b4ed18f8e8b072f150d 284 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 130 152 8.6E-30 T 29-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) CDC59_RS20035 057e1664d99b6b4ed18f8e8b072f150d 284 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 86 107 8.6E-30 T 29-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) CDC59_RS20035 057e1664d99b6b4ed18f8e8b072f150d 284 Gene3D G3DSA:2.120.10.30 2 263 1.3E-38 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CDC59_RS20035 057e1664d99b6b4ed18f8e8b072f150d 284 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 5 255 1.6E-78 T 29-03-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region CDC59_RS04805 e33c70c9646e3e7fb20df1f1f7676b0b 153 Gene3D G3DSA:3.90.79.10 2 151 1.9E-21 T 29-03-2018 CDC59_RS04805 e33c70c9646e3e7fb20df1f1f7676b0b 153 Pfam PF00293 NUDIX domain 7 65 5.1E-13 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CDC59_RS04805 e33c70c9646e3e7fb20df1f1f7676b0b 153 SUPERFAMILY SSF55811 6 130 4.87E-20 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CDC59_RS04540 3f731e0a786db3beaed271543ac2818d 233 SUPERFAMILY SSF53335 18 195 3.77E-42 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS04540 3f731e0a786db3beaed271543ac2818d 233 Gene3D G3DSA:3.40.50.150 12 231 2.6E-32 T 29-03-2018 CDC59_RS04540 3f731e0a786db3beaed271543ac2818d 233 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 27 223 5.1E-31 T 29-03-2018 CDC59_RS15205 4218e9839c4e48770848cae6e3a50613 156 Gene3D G3DSA:2.60.120.10 4 145 8.5E-21 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CDC59_RS15205 4218e9839c4e48770848cae6e3a50613 156 SUPERFAMILY SSF51182 11 135 1.26E-25 T 29-03-2018 IPR011051 RmlC-like cupin domain CDC59_RS15205 4218e9839c4e48770848cae6e3a50613 156 Pfam PF07883 Cupin domain 53 124 2.1E-11 T 29-03-2018 IPR013096 Cupin 2, conserved barrel CDC59_RS12280 05530c6ac563d3c5a805661cf66ae91f 1299 Gene3D G3DSA:2.40.128.110 990 1060 0.013 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CDC59_RS12280 05530c6ac563d3c5a805661cf66ae91f 1299 Pfam PF04357 TamB, inner membrane protein subunit of TAM complex 958 1299 4.8E-58 T 29-03-2018 IPR007452 Translocation and assembly module TamB CDC59_RS15475 1e130a91f98cad3e14624f796a23a639 297 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 4 287 7.1E-59 T 29-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 CDC59_RS15475 1e130a91f98cad3e14624f796a23a639 297 PIRSF PIRSF026649 1 297 2.8E-79 T 29-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 CDC59_RS22235 5342259e41e8382de9a02ff6187a6829 1111 Pfam PF05567 Neisseria PilC beta-propeller domain 519 906 3.1E-45 T 29-03-2018 IPR008707 PilC beta-propeller domain CDC59_RS22235 5342259e41e8382de9a02ff6187a6829 1111 SUPERFAMILY SSF49899 66 195 3.29E-16 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CDC59_RS22235 5342259e41e8382de9a02ff6187a6829 1111 SUPERFAMILY SSF49899 271 369 3.29E-16 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CDC59_RS22235 5342259e41e8382de9a02ff6187a6829 1111 Gene3D G3DSA:2.60.120.200 78 395 8.2E-41 T 29-03-2018 CDC59_RS23005 dc9bd5fb5518d02e3c979b153dd27603 703 Gene3D G3DSA:1.25.40.20 517 692 0.0076 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CDC59_RS23005 dc9bd5fb5518d02e3c979b153dd27603 703 Gene3D G3DSA:1.25.40.20 190 454 1.8E-4 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CDC59_RS23005 dc9bd5fb5518d02e3c979b153dd27603 703 SUPERFAMILY SSF48403 284 367 5.29E-5 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CDC59_RS23005 dc9bd5fb5518d02e3c979b153dd27603 703 SUPERFAMILY SSF48403 612 680 5.29E-5 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CDC59_RS23005 dc9bd5fb5518d02e3c979b153dd27603 703 Pfam PF07906 ShET2 enterotoxin, N-terminal region 5 226 7.2E-26 T 29-03-2018 IPR012927 ShET2 enterotoxin, N-terminal CDC59_RS09175 c5394233a43165a401d1d22685af2ab9 271 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 232 258 - T 29-03-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 CDC59_RS09175 c5394233a43165a401d1d22685af2ab9 271 Pfam PF01148 Cytidylyltransferase family 4 269 1.4E-56 T 29-03-2018 CDC59_RS04995 676b22b42c68a4aa1f92bdf43b5a0b4b 450 Gene3D G3DSA:2.60.120.260 23 226 8.6E-5 T 29-03-2018 IPR008979 Galactose-binding domain-like CDC59_RS04995 676b22b42c68a4aa1f92bdf43b5a0b4b 450 Pfam PF13163 Protein of unknown function (DUF3999) 29 438 1.4E-121 T 29-03-2018 IPR025060 Protein of unknown function DUF3999 CDC59_RS16500 d0ce1d7d726fda9d796b9837c83b3e20 411 SUPERFAMILY SSF51395 2 356 4.58E-102 T 29-03-2018 CDC59_RS16500 d0ce1d7d726fda9d796b9837c83b3e20 411 Gene3D G3DSA:3.20.20.70 1 367 3.9E-109 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CDC59_RS16500 d0ce1d7d726fda9d796b9837c83b3e20 411 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 2 340 1.2E-54 T 29-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CDC59_RS21845 e848c0603a393efb78fc5cccf2e09b73 450 Pfam PF02447 GntP family permease 10 447 4.3E-159 T 29-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CDC59_RS21845 e848c0603a393efb78fc5cccf2e09b73 450 PIRSF PIRSF002746 5 450 4.2E-156 T 29-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CDC59_RS21845 e848c0603a393efb78fc5cccf2e09b73 450 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 10 450 6.5E-150 T 29-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CDC59_RS08495 f353566cdf0c035ea8e083a7d9a3d5e5 57 TIGRFAM TIGR00847 ccoS: cytochrome oxidase maturation protein, cbb3-type 1 46 3.6E-14 T 29-03-2018 IPR004714 Cytochrome oxidase maturation protein cbb3-type CDC59_RS08495 f353566cdf0c035ea8e083a7d9a3d5e5 57 Pfam PF03597 Cytochrome oxidase maturation protein cbb3-type 2 44 9.9E-19 T 29-03-2018 IPR004714 Cytochrome oxidase maturation protein cbb3-type CDC59_RS10455 74213c06b34f41847611a66dc48bc6ed 148 SUPERFAMILY SSF54637 8 143 5.31E-40 T 29-03-2018 IPR029069 HotDog domain CDC59_RS10455 74213c06b34f41847611a66dc48bc6ed 148 Pfam PF03061 Thioesterase superfamily 28 110 4.4E-15 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CDC59_RS10455 74213c06b34f41847611a66dc48bc6ed 148 Gene3D G3DSA:3.10.129.10 1 142 1.7E-40 T 29-03-2018 CDC59_RS00775 fd5f0d701b7ed00e3a2f4e6c6b6c3167 71 ProDom PD056452 UNCHARACTERIZED BACTERIA SIMILAR YPEB CYTOPLASMIC VCA0163 PRODUCT STM2426 GENE YPO2988 14 70 3.0E-26 T 29-03-2018 IPR024530 Putative quorum-sensing-regulated virulence factor CDC59_RS00775 fd5f0d701b7ed00e3a2f4e6c6b6c3167 71 Pfam PF12843 Putative quorum-sensing-regulated virulence factor 3 67 2.1E-30 T 29-03-2018 IPR024530 Putative quorum-sensing-regulated virulence factor CDC59_RS13375 789d4a941a5ef49cdd121ba7773e785a 65 Gene3D G3DSA:2.60.260.40 1 56 1.5E-17 T 29-03-2018 CDC59_RS13375 789d4a941a5ef49cdd121ba7773e785a 65 Pfam PF10276 Zinc-finger domain 30 53 1.3E-9 T 29-03-2018 IPR019401 Zinc finger, CHCC-type Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS23570 ab6289746fb1378a3060a05a9f909600 316 SUPERFAMILY SSF103481 61 163 1.83E-17 T 29-03-2018 CDC59_RS23570 ab6289746fb1378a3060a05a9f909600 316 Pfam PF00892 EamA-like transporter family 31 161 7.8E-25 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CDC59_RS23570 ab6289746fb1378a3060a05a9f909600 316 Pfam PF00892 EamA-like transporter family 178 314 3.2E-18 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CDC59_RS23570 ab6289746fb1378a3060a05a9f909600 316 SUPERFAMILY SSF103481 234 315 1.06E-9 T 29-03-2018 CDC59_RS10285 b19d4890843097c07db17c08419f443f 353 Pfam PF06250 Protein of unknown function (DUF1016) 29 340 2.0E-118 T 29-03-2018 IPR009362 Protein of unknown function DUF1016 CDC59_RS17350 e87471204357371469ae168a4132fb05 611 Pfam PF06276 Ferric iron reductase FhuF-like transporter 441 587 1.1E-30 T 29-03-2018 IPR022770 Ferric iron reductase FhuF domain CDC59_RS17350 e87471204357371469ae168a4132fb05 611 Pfam PF04183 IucA / IucC family 188 412 7.7E-53 T 29-03-2018 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0015343|GO:0019290 CDC59_RS02740 a26dbdd69286f6db6a4c1a8f944a9ecb 274 Pfam PF16344 Domain of unknown function (DUF4974) 182 262 1.2E-7 T 29-03-2018 IPR032508 Protein FecR, C-terminal CDC59_RS02740 a26dbdd69286f6db6a4c1a8f944a9ecb 274 Pfam PF04773 FecR protein 65 155 4.0E-21 T 29-03-2018 IPR006860 FecR protein CDC59_RS02740 a26dbdd69286f6db6a4c1a8f944a9ecb 274 PIRSF PIRSF018266 2 270 1.2E-70 T 29-03-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component CDC59_RS20395 e829abd22fe1c2e1b760d2d8dcf338d9 109 Pfam PF12769 4TM region of pyridine nucleotide transhydrogenase, mitoch 11 94 7.8E-36 T 29-03-2018 IPR024605 NAD(P) transhydrogenase, alpha subunit, C-terminal KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 CDC59_RS00720 f959cd16f9142311a67f7be1a90393ae 294 Pfam PF02653 Branched-chain amino acid transport system / permease component 16 284 9.0E-39 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CDC59_RS00720 f959cd16f9142311a67f7be1a90393ae 294 Gene3D G3DSA:1.10.3470.10 5 287 1.3E-42 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CDC59_RS05160 99577862204153bf9a3d113b796b3eb4 1046 Gene3D G3DSA:3.40.50.1820 327 604 1.1E-4 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CDC59_RS05160 99577862204153bf9a3d113b796b3eb4 1046 Gene3D G3DSA:3.30.460.10 605 745 0.16 T 29-03-2018 CDC59_RS05160 99577862204153bf9a3d113b796b3eb4 1046 Gene3D G3DSA:3.30.460.10 831 975 0.0014 T 29-03-2018 CDC59_RS13100 ea059bd8c83b5bbb5e8593db911e40f6 189 Pfam PF12306 Inclusion body protein 21 186 4.6E-38 T 29-03-2018 IPR021087 Uncharacterised protein family PixA/AidA CDC59_RS23590 6b3dcd4650105e1fb05f2ed74afa6973 519 Gene3D G3DSA:2.100.10.30 365 512 1.3E-24 T 29-03-2018 CDC59_RS23590 6b3dcd4650105e1fb05f2ed74afa6973 519 SUPERFAMILY SSF51101 367 509 4.06E-21 T 29-03-2018 IPR001229 Jacalin-like lectin domain CDC59_RS12375 b8d1b2ef4f3ec7a580e6b248d7a7ffed 105 SUPERFAMILY SSF102829 5 99 5.62E-19 T 29-03-2018 IPR007838 Cell division protein ZapA-like CDC59_RS12375 b8d1b2ef4f3ec7a580e6b248d7a7ffed 105 Pfam PF05164 Cell division protein ZapA 6 93 1.6E-18 T 29-03-2018 IPR007838 Cell division protein ZapA-like CDC59_RS06970 d5d06afa2c6a248ce2eef4934f5c2e0e 220 SUPERFAMILY SSF51197 4 211 3.66E-27 T 29-03-2018 CDC59_RS06970 d5d06afa2c6a248ce2eef4934f5c2e0e 220 Gene3D G3DSA:2.60.120.620 3 219 1.1E-21 T 29-03-2018 CDC59_RS06970 d5d06afa2c6a248ce2eef4934f5c2e0e 220 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 5 200 1.5E-21 T 29-03-2018 IPR008775 Phytanoyl-CoA dioxygenase CDC59_RS14420 b519ff15ae7605da7ffd678dea699df0 310 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 19 300 18.909 T 29-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 CDC59_RS14420 b519ff15ae7605da7ffd678dea699df0 310 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 74 96 - T 29-03-2018 IPR030470 UbiA prenyltransferase conserved site CDC59_RS14420 b519ff15ae7605da7ffd678dea699df0 310 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 22 299 1.1E-89 T 29-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 CDC59_RS14420 b519ff15ae7605da7ffd678dea699df0 310 Pfam PF01040 UbiA prenyltransferase family 35 281 4.7E-58 T 29-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 CDC59_RS09620 ee1e98175e486c8c1dcd51fd32d1e00a 69 Gene3D G3DSA:2.30.30.320 1 69 2.8E-16 T 29-03-2018 IPR023387 DUF1653-like domain CDC59_RS09620 ee1e98175e486c8c1dcd51fd32d1e00a 69 Pfam PF07866 Protein of unknown function (DUF1653) 8 66 2.0E-18 T 29-03-2018 IPR023387 DUF1653-like domain CDC59_RS09770 f84244534d8d3eb3a804735be5e3d6bd 382 Pfam PF00465 Iron-containing alcohol dehydrogenase 9 373 1.5E-104 T 29-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CDC59_RS09770 f84244534d8d3eb3a804735be5e3d6bd 382 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 172 200 - T 29-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 CDC59_RS09770 f84244534d8d3eb3a804735be5e3d6bd 382 SUPERFAMILY SSF56796 5 380 1.44E-107 T 29-03-2018 CDC59_RS09770 f84244534d8d3eb3a804735be5e3d6bd 382 Gene3D G3DSA:3.40.50.1970 8 182 1.6E-42 T 29-03-2018 CDC59_RS09770 f84244534d8d3eb3a804735be5e3d6bd 382 Gene3D G3DSA:1.20.1090.10 183 382 9.6E-51 T 29-03-2018 CDC59_RS10795 24ba7210c1b7849459c044199bf205ec 105 Pfam PF06127 Protein of unknown function (DUF962) 10 102 6.1E-36 T 29-03-2018 IPR009305 Protein of unknown function DUF962 CDC59_RS00165 97444a7c2b6d5dd690b9edf4312447e6 497 Gene3D G3DSA:3.40.605.10 17 282 3.2E-103 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CDC59_RS00165 97444a7c2b6d5dd690b9edf4312447e6 497 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 292 303 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CDC59_RS00165 97444a7c2b6d5dd690b9edf4312447e6 497 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 264 271 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CDC59_RS00165 97444a7c2b6d5dd690b9edf4312447e6 497 SUPERFAMILY SSF53720 12 493 3.93E-173 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CDC59_RS00165 97444a7c2b6d5dd690b9edf4312447e6 497 Gene3D G3DSA:3.40.309.10 283 477 1.4E-75 T 29-03-2018 CDC59_RS00165 97444a7c2b6d5dd690b9edf4312447e6 497 TIGRFAM TIGR01780 SSADH: succinate-semialdehyde dehydrogenase 40 489 1.5E-217 T 29-03-2018 IPR010102 Succinate semialdehyde dehydrogenase GO:0009013|GO:0009450|GO:0055114 Reactome: R-HSA-916853 CDC59_RS00165 97444a7c2b6d5dd690b9edf4312447e6 497 Pfam PF00171 Aldehyde dehydrogenase family 29 491 8.6E-174 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CDC59_RS15490 f39076176584d29f576039adb226ffa2 97 Pfam PF08734 GYD domain 4 92 1.8E-32 T 29-03-2018 IPR014845 Uncharacterised protein GYD CDC59_RS15160 b5643a483555e09df7691554ec2a5972 448 TIGRFAM TIGR00937 2A51: chromate efflux transporter 23 399 1.6E-71 T 29-03-2018 IPR014047 Chromate transporter, long chain CDC59_RS15160 b5643a483555e09df7691554ec2a5972 448 Pfam PF02417 Chromate transporter 18 180 2.5E-36 T 29-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 CDC59_RS15160 b5643a483555e09df7691554ec2a5972 448 Pfam PF02417 Chromate transporter 256 440 5.8E-34 T 29-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 CDC59_RS15160 b5643a483555e09df7691554ec2a5972 448 PIRSF PIRSF004810 1 447 1.4E-129 T 29-03-2018 IPR014047 Chromate transporter, long chain CDC59_RS18830 a80df3e3a890b31f6113d3d3d813e6ff 452 SUPERFAMILY SSF56954 22 447 1.7E-70 T 29-03-2018 CDC59_RS18830 a80df3e3a890b31f6113d3d3d813e6ff 452 Pfam PF02321 Outer membrane efflux protein 68 247 2.8E-18 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CDC59_RS18830 a80df3e3a890b31f6113d3d3d813e6ff 452 Pfam PF02321 Outer membrane efflux protein 273 447 5.9E-27 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CDC59_RS18830 a80df3e3a890b31f6113d3d3d813e6ff 452 Gene3D G3DSA:1.20.1600.10 52 451 1.5E-66 T 29-03-2018 CDC59_RS05120 b5040ac8d247ea880788c35808bc99a0 128 Gene3D G3DSA:1.10.760.10 12 128 6.7E-7 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS05120 b5040ac8d247ea880788c35808bc99a0 128 SUPERFAMILY SSF46626 48 116 1.6E-15 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS07215 f5351d6a985cc949856935e15c38c2a1 469 Pfam PF16980 Putative citrate transport 24 468 3.2E-194 T 29-03-2018 IPR031566 Putative citrate transporter CDC59_RS19630 299036f93c83d3584bc495f10ffa8e85 199 Gene3D G3DSA:1.25.40.10 27 112 5.0E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS19630 299036f93c83d3584bc495f10ffa8e85 199 SUPERFAMILY SSF48452 29 102 2.0E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS14470 33b7bb924db9b965e86e659dbf16b997 171 PIRSF PIRSF032162 1 171 8.3E-61 T 29-03-2018 IPR016990 Uncharacterised conserved protein UCP032162, transmembrane CDC59_RS14470 33b7bb924db9b965e86e659dbf16b997 171 Pfam PF10003 Integral membrane protein (DUF2244) 27 162 4.8E-47 T 29-03-2018 IPR019253 Protein of unknown function DUF2244, transmembrane CDC59_RS07685 b4551e41155213829d906b0e2a324c27 96 SUPERFAMILY SSF54909 1 96 2.84E-27 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CDC59_RS07685 b4551e41155213829d906b0e2a324c27 96 Gene3D G3DSA:3.30.70.100 1 96 9.4E-26 T 29-03-2018 CDC59_RS07685 b4551e41155213829d906b0e2a324c27 96 Pfam PF07045 Domain of unknown function (DUF1330) 4 96 7.7E-34 T 29-03-2018 IPR010753 Domain of unknown function DUF1330 CDC59_RS17035 804de6722a849185823435563a13d474 244 PRINTS PR01008 Flagellar L-ring protein signature 87 99 2.6E-26 T 29-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 CDC59_RS17035 804de6722a849185823435563a13d474 244 PRINTS PR01008 Flagellar L-ring protein signature 158 173 2.6E-26 T 29-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 CDC59_RS17035 804de6722a849185823435563a13d474 244 PRINTS PR01008 Flagellar L-ring protein signature 184 200 2.6E-26 T 29-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 CDC59_RS17035 804de6722a849185823435563a13d474 244 PRINTS PR01008 Flagellar L-ring protein signature 205 219 2.6E-26 T 29-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 CDC59_RS17035 804de6722a849185823435563a13d474 244 PRINTS PR01008 Flagellar L-ring protein signature 221 235 2.6E-26 T 29-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 CDC59_RS17035 804de6722a849185823435563a13d474 244 Hamap MF_00415 Flagellar L-ring protein [flgH]. 18 242 24.784 T 29-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 CDC59_RS17035 804de6722a849185823435563a13d474 244 Pfam PF02107 Flagellar L-ring protein 60 243 5.0E-56 T 29-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 CDC59_RS13145 3dc48fa9b84977029d2bf700814d177c 222 Gene3D G3DSA:3.40.50.720 1 142 1.3E-7 T 29-03-2018 CDC59_RS13145 3dc48fa9b84977029d2bf700814d177c 222 SUPERFAMILY SSF51735 1 204 3.37E-23 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS11040 a0c07ba4f5bfe74922fd82d660bd5aef 548 SUPERFAMILY SSF52833 219 379 2.83E-14 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS11040 a0c07ba4f5bfe74922fd82d660bd5aef 548 Pfam PF02630 SCO1/SenC 223 304 6.7E-5 T 29-03-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS11040 a0c07ba4f5bfe74922fd82d660bd5aef 548 Gene3D G3DSA:3.40.30.10 220 379 1.6E-11 T 29-03-2018 CDC59_RS00150 3ff7a5b556e2d8b78ee19311c562c8e0 173 TIGRFAM TIGR01841 phasin: phasin family protein 27 110 1.9E-25 T 29-03-2018 IPR010127 Phasin, subfamily 1 CDC59_RS00150 3ff7a5b556e2d8b78ee19311c562c8e0 173 Pfam PF09361 Phasin protein 5 101 2.9E-23 T 29-03-2018 IPR018968 Phasin CDC59_RS02610 7c7714ae7e8c3825ad3d6fcdff6ac83e 141 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 5 109 32.402 T 29-03-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CDC59_RS02610 7c7714ae7e8c3825ad3d6fcdff6ac83e 141 SUPERFAMILY SSF141734 4 110 5.36E-47 T 29-03-2018 CDC59_RS02610 7c7714ae7e8c3825ad3d6fcdff6ac83e 141 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 31 105 1.2E-35 T 29-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CDC59_RS02610 7c7714ae7e8c3825ad3d6fcdff6ac83e 141 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 54 107 6.0E-25 T 29-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CDC59_RS10615 1dd00645281e96f457d56c0e43fc6203 190 Gene3D G3DSA:1.10.443.10 2 184 6.1E-22 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CDC59_RS10615 1dd00645281e96f457d56c0e43fc6203 190 SUPERFAMILY SSF56349 6 170 7.95E-23 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CDC59_RS10615 1dd00645281e96f457d56c0e43fc6203 190 Pfam PF00589 Phage integrase family 13 170 1.6E-15 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CDC59_RS15680 1e343066c4f0969d366d1aba666f8c9e 201 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 21 197 2.2E-26 T 29-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CDC59_RS15680 1e343066c4f0969d366d1aba666f8c9e 201 Gene3D G3DSA:3.40.50.10420 9 201 1.7E-46 T 29-03-2018 CDC59_RS15680 1e343066c4f0969d366d1aba666f8c9e 201 PIRSF PIRSF006806 15 200 3.3E-29 T 29-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CDC59_RS15680 1e343066c4f0969d366d1aba666f8c9e 201 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 21 197 2.8E-37 T 29-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CDC59_RS15680 1e343066c4f0969d366d1aba666f8c9e 201 SUPERFAMILY SSF100950 19 201 4.19E-43 T 29-03-2018 CDC59_RS17300 ffe7bd12893d27a5c6ff3ed37660db99 411 SUPERFAMILY SSF103473 21 406 9.68E-55 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS17300 ffe7bd12893d27a5c6ff3ed37660db99 411 Pfam PF07690 Major Facilitator Superfamily 28 368 5.2E-39 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CDC59_RS17300 ffe7bd12893d27a5c6ff3ed37660db99 411 Gene3D G3DSA:1.20.1250.20 18 210 4.3E-20 T 29-03-2018 CDC59_RS17300 ffe7bd12893d27a5c6ff3ed37660db99 411 Gene3D G3DSA:1.20.1250.20 227 411 3.4E-23 T 29-03-2018 CDC59_RS16715 423e2015d6247897de995afd437c108d 543 Pfam PF13520 Amino acid permease 11 426 2.9E-52 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CDC59_RS16715 423e2015d6247897de995afd437c108d 543 PIRSF PIRSF006060 2 530 1.7E-71 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CDC59_RS12560 00b80bc7d73ca1abc9f86f303d847ffe 159 Gene3D G3DSA:3.10.50.40 7 159 2.0E-19 T 29-03-2018 CDC59_RS12560 00b80bc7d73ca1abc9f86f303d847ffe 159 SUPERFAMILY SSF54534 19 158 2.95E-31 T 29-03-2018 CDC59_RS12560 00b80bc7d73ca1abc9f86f303d847ffe 159 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 19 156 6.2E-12 T 29-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain CDC59_RS22500 5600f3d62f0dce8e55a364516c6c030d 462 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 8 429 6.1E-150 T 29-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 CDC59_RS22500 5600f3d62f0dce8e55a364516c6c030d 462 PIRSF PIRSF006446 1 456 3.1E-171 T 29-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 CDC59_RS17935 e4dc156dad41a49f31b83799c34e3ca4 279 Hamap MF_00662 Phosphatidylserine decarboxylase proenzyme [psd]. 10 279 42.61 T 29-03-2018 IPR033178 Phosphatidylserine decarboxylase, prokaryotic type 1 GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 CDC59_RS17935 e4dc156dad41a49f31b83799c34e3ca4 279 Pfam PF02666 Phosphatidylserine decarboxylase 63 278 8.4E-61 T 29-03-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 CDC59_RS17935 e4dc156dad41a49f31b83799c34e3ca4 279 TIGRFAM TIGR00163 PS_decarb: phosphatidylserine decarboxylase 56 278 2.5E-70 T 29-03-2018 IPR033177 Phosphatidylserine decarboxylase GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 CDC59_RS05850 cef747857c57e5dc09a20be81c7a471a 275 Pfam PF06629 MltA-interacting protein MipA 53 274 1.2E-45 T 29-03-2018 IPR010583 MltA-interacting MipA CDC59_RS05850 cef747857c57e5dc09a20be81c7a471a 275 Gene3D G3DSA:2.40.160.20 26 274 3.1E-5 T 29-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CDC59_RS13185 9a464df072030a3f48fb92d58f918d80 243 Pfam PF04403 Paraquat-inducible protein A 77 233 3.0E-54 T 29-03-2018 IPR007498 Paraquat-inducible protein A CDC59_RS21460 087e7153b9f38c1c0d874e2f14a447d8 308 Gene3D G3DSA:1.20.1560.10 5 308 0.002 T 29-03-2018 CDC59_RS21460 087e7153b9f38c1c0d874e2f14a447d8 308 Pfam PF00482 Type II secretion system (T2SS), protein F 141 267 7.7E-13 T 29-03-2018 IPR018076 Type II secretion system F domain CDC59_RS20040 88429faab4df1fea00b2da293ad2c4f6 679 SUPERFAMILY SSF51126 339 520 6.11E-62 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CDC59_RS20040 88429faab4df1fea00b2da293ad2c4f6 679 SUPERFAMILY SSF51126 558 602 6.11E-62 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CDC59_RS20040 88429faab4df1fea00b2da293ad2c4f6 679 SUPERFAMILY SSF51126 137 276 6.11E-62 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CDC59_RS20040 88429faab4df1fea00b2da293ad2c4f6 679 SUPERFAMILY SSF51126 91 109 6.11E-62 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CDC59_RS20040 88429faab4df1fea00b2da293ad2c4f6 679 Gene3D G3DSA:2.160.20.10 97 677 3.2E-74 T 29-03-2018 IPR012334 Pectin lyase fold CDC59_RS20040 88429faab4df1fea00b2da293ad2c4f6 679 ProSitePatterns PS00502 Polygalacturonase active site. 445 459 - T 29-03-2018 IPR000743 Glycoside hydrolase, family 28 GO:0004650|GO:0005975 CDC59_RS20040 88429faab4df1fea00b2da293ad2c4f6 679 Pfam PF00295 Glycosyl hydrolases family 28 350 511 6.5E-15 T 29-03-2018 IPR000743 Glycoside hydrolase, family 28 GO:0004650|GO:0005975 CDC59_RS05410 ff9cb7bebf78b5a84b72abb92be91b13 158 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 14 138 6.8E-25 T 29-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CDC59_RS05410 ff9cb7bebf78b5a84b72abb92be91b13 158 Gene3D G3DSA:3.30.530.20 1 140 3.4E-27 T 29-03-2018 IPR023393 START-like domain CDC59_RS05410 ff9cb7bebf78b5a84b72abb92be91b13 158 SUPERFAMILY SSF55961 2 143 4.84E-32 T 29-03-2018 CDC59_RS02175 4da66209f3796d6c6693db6f1d046045 242 Gene3D G3DSA:3.90.1720.10 35 223 2.7E-10 T 29-03-2018 CDC59_RS02175 4da66209f3796d6c6693db6f1d046045 242 Pfam PF06672 Protein of unknown function (DUF1175) 38 241 3.7E-82 T 29-03-2018 IPR009558 Protein of unknown function DUF1175 CDC59_RS13485 b31fd56906d601088ba3aecce180f82c 398 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 293 309 1.1E-10 T 29-03-2018 CDC59_RS13485 b31fd56906d601088ba3aecce180f82c 398 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 8 30 1.1E-10 T 29-03-2018 CDC59_RS13485 b31fd56906d601088ba3aecce180f82c 398 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 146 161 1.1E-10 T 29-03-2018 CDC59_RS13485 b31fd56906d601088ba3aecce180f82c 398 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 278 293 1.1E-10 T 29-03-2018 CDC59_RS13485 b31fd56906d601088ba3aecce180f82c 398 Pfam PF01494 FAD binding domain 9 336 2.4E-22 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 CDC59_RS13485 b31fd56906d601088ba3aecce180f82c 398 SUPERFAMILY SSF51905 8 167 6.48E-47 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS13485 b31fd56906d601088ba3aecce180f82c 398 SUPERFAMILY SSF51905 265 364 6.48E-47 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS13485 b31fd56906d601088ba3aecce180f82c 398 Gene3D G3DSA:3.50.50.60 8 345 2.7E-37 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS21125 8447183e6db7e593697fc9677c05e8b2 89 Pfam PF10048 Predicted integral membrane protein (DUF2282) 33 82 1.8E-24 T 29-03-2018 IPR018740 Protein of unknown function DUF2282, integral membrane CDC59_RS16335 d20d972c1eca23831333562bda577ec1 214 Gene3D G3DSA:3.40.1050.10 3 205 1.2E-65 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CDC59_RS16335 d20d972c1eca23831333562bda577ec1 214 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 82 102 - T 29-03-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CDC59_RS16335 d20d972c1eca23831333562bda577ec1 214 SMART SM00947 30 192 4.8E-57 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CDC59_RS16335 d20d972c1eca23831333562bda577ec1 214 Pfam PF00484 Carbonic anhydrase 37 188 6.9E-46 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CDC59_RS16335 d20d972c1eca23831333562bda577ec1 214 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 42 49 - T 29-03-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CDC59_RS16335 d20d972c1eca23831333562bda577ec1 214 SUPERFAMILY SSF53056 4 191 3.01E-64 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CDC59_RS19620 a800ff16a16f50a8d4ccf0f3c2e084ce 448 TIGRFAM TIGR03353 VI_chp_4: type VI secretion protein, VC_A0114 family 6 447 2.2E-149 T 29-03-2018 IPR010263 Type VI secretion protein, VC_A0114 CDC59_RS19620 a800ff16a16f50a8d4ccf0f3c2e084ce 448 Pfam PF05936 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE 19 446 2.5E-140 T 29-03-2018 IPR010263 Type VI secretion protein, VC_A0114 CDC59_RS11530 c2316689aeae734aea9b48b072ec34fe 403 Pfam PF11062 Protein of unknown function (DUF2863) 5 402 6.2E-180 T 29-03-2018 IPR021292 Protein of unknown function DUF2863 CDC59_RS15030 c59cab92bf84fea733a618b6758a6b4c 167 Pfam PF04073 Aminoacyl-tRNA editing domain 38 153 1.0E-25 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CDC59_RS15030 c59cab92bf84fea733a618b6758a6b4c 167 Gene3D G3DSA:3.90.960.10 2 166 4.6E-35 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CDC59_RS15030 c59cab92bf84fea733a618b6758a6b4c 167 SUPERFAMILY SSF55826 17 163 7.33E-32 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CDC59_RS19300 a314c6d017e48205778f024cf4f24aa7 51 Pfam PF11752 Protein of unknown function (DUF3309) 3 49 4.1E-20 T 29-03-2018 IPR021738 Protein of unknown function DUF3309 CDC59_RS11025 5915db75458e476faa7ea5ad0489721e 63 Pfam PF11127 Protein of unknown function (DUF2892) 1 61 8.3E-22 T 29-03-2018 IPR021309 Protein of unknown function DUF2892 CDC59_RS05020 02d206ff173df281b4a4005deb080064 500 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 20 438 4.5E-151 T 29-03-2018 IPR002823 Protein of unknown function DUF112, transmembrane CDC59_RS04710 e32cae2dbe2601e1ee8762e798621322 149 Pfam PF03477 ATP cone domain 51 136 1.1E-14 T 29-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 CDC59_RS04710 e32cae2dbe2601e1ee8762e798621322 149 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 149 82.878 T 29-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 CDC59_RS04710 e32cae2dbe2601e1ee8762e798621322 149 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 146 5.5E-56 T 29-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 CDC59_RS06360 7fa92c90d3b76db84c6a58b2128144ca 369 Pfam PF02653 Branched-chain amino acid transport system / permease component 73 353 2.0E-39 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CDC59_RS06360 7fa92c90d3b76db84c6a58b2128144ca 369 Gene3D G3DSA:1.10.3470.10 47 357 4.0E-31 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CDC59_RS21700 b63161de71331c833409fe88e89062b5 82 Pfam PF06906 Protein of unknown function (DUF1272) 1 57 1.1E-30 T 29-03-2018 IPR010696 Protein of unknown function DUF1272 CDC59_RS05560 80296206c8e8b34066c2bfe7e317f39f 293 SUPERFAMILY SSF53335 19 255 6.66E-48 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS05560 80296206c8e8b34066c2bfe7e317f39f 293 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 35 41 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CDC59_RS05560 80296206c8e8b34066c2bfe7e317f39f 293 Pfam PF01555 DNA methylase 32 241 2.8E-34 T 29-03-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 CDC59_RS05560 80296206c8e8b34066c2bfe7e317f39f 293 Gene3D G3DSA:3.40.50.150 3 271 2.8E-41 T 29-03-2018 CDC59_RS05560 80296206c8e8b34066c2bfe7e317f39f 293 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 84 104 9.8E-23 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CDC59_RS05560 80296206c8e8b34066c2bfe7e317f39f 293 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 202 220 9.8E-23 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CDC59_RS05560 80296206c8e8b34066c2bfe7e317f39f 293 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 225 245 9.8E-23 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CDC59_RS05560 80296206c8e8b34066c2bfe7e317f39f 293 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 31 45 9.8E-23 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CDC59_RS05560 80296206c8e8b34066c2bfe7e317f39f 293 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 183 200 9.8E-23 T 29-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CDC59_RS05225 d7c976a5c499df17f966051d63e5e596 370 Gene3D G3DSA:1.20.1170.10 27 298 8.8E-4 T 29-03-2018 CDC59_RS09230 ba47919a7b65ee391dafe8c3de45dadb 291 Gene3D G3DSA:3.90.230.10 10 280 2.4E-26 T 29-03-2018 CDC59_RS09230 ba47919a7b65ee391dafe8c3de45dadb 291 SUPERFAMILY SSF55920 233 270 6.15E-21 T 29-03-2018 IPR000994 Peptidase M24 CDC59_RS09230 ba47919a7b65ee391dafe8c3de45dadb 291 SUPERFAMILY SSF55920 12 204 6.15E-21 T 29-03-2018 IPR000994 Peptidase M24 CDC59_RS09230 ba47919a7b65ee391dafe8c3de45dadb 291 Pfam PF00557 Metallopeptidase family M24 16 263 3.7E-23 T 29-03-2018 IPR000994 Peptidase M24 CDC59_RS04295 1dbef0cfce3b643fe3359bcbcbf3ae57 352 Gene3D G3DSA:3.90.550.10 2 198 2.3E-29 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDC59_RS04295 1dbef0cfce3b643fe3359bcbcbf3ae57 352 Pfam PF00535 Glycosyl transferase family 2 12 174 1.3E-29 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CDC59_RS04295 1dbef0cfce3b643fe3359bcbcbf3ae57 352 SUPERFAMILY SSF53448 5 261 1.41E-35 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDC59_RS08360 8e287252b6611b1e06b97c7e9aefa4f2 342 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 131 229 1.1E-5 T 29-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CDC59_RS08360 8e287252b6611b1e06b97c7e9aefa4f2 342 TIGRFAM TIGR04380 myo_inos_iolG: inositol 2-dehydrogenase 1 326 1.6E-129 T 29-03-2018 IPR030827 Inositol 2-dehydrogenase CDC59_RS08360 8e287252b6611b1e06b97c7e9aefa4f2 342 SUPERFAMILY SSF51735 3 142 1.55E-41 T 29-03-2018 IPR016040 NAD(P)-binding domain CDC59_RS08360 8e287252b6611b1e06b97c7e9aefa4f2 342 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 3 119 8.1E-23 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CDC59_RS08360 8e287252b6611b1e06b97c7e9aefa4f2 342 Gene3D G3DSA:3.40.50.720 1 130 5.3E-37 T 29-03-2018 CDC59_RS08360 8e287252b6611b1e06b97c7e9aefa4f2 342 SUPERFAMILY SSF55347 124 286 8.9E-31 T 29-03-2018 CDC59_RS08360 8e287252b6611b1e06b97c7e9aefa4f2 342 Gene3D G3DSA:3.30.360.10 131 337 6.3E-44 T 29-03-2018 CDC59_RS14120 3cbf3de212551b444425d46d37dba1c4 410 SUPERFAMILY SSF53901 209 402 3.93E-51 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS14120 3cbf3de212551b444425d46d37dba1c4 410 Gene3D G3DSA:3.40.47.10 257 405 1.6E-45 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS14120 3cbf3de212551b444425d46d37dba1c4 410 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 153 169 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site CDC59_RS14120 3cbf3de212551b444425d46d37dba1c4 410 SUPERFAMILY SSF53901 10 237 2.22E-39 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS14120 3cbf3de212551b444425d46d37dba1c4 410 SMART SM00825 Beta-ketoacyl synthase 32 403 3.2E-10 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CDC59_RS14120 3cbf3de212551b444425d46d37dba1c4 410 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 92 237 3.6E-27 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CDC59_RS14120 3cbf3de212551b444425d46d37dba1c4 410 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 253 359 4.6E-27 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CDC59_RS14120 3cbf3de212551b444425d46d37dba1c4 410 Gene3D G3DSA:3.40.47.10 5 243 5.5E-38 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS00325 15bf63699ab2bfbdd0737523c34816a1 88 Gene3D G3DSA:3.40.50.150 1 80 8.3E-4 T 29-03-2018 CDC59_RS11775 22712b21bd1f742155b86a7f293280bb 354 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 18 349 24.661 T 29-03-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS11775 22712b21bd1f742155b86a7f293280bb 354 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 230 243 - T 29-03-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS11775 22712b21bd1f742155b86a7f293280bb 354 Pfam PF00146 NADH dehydrogenase 26 342 5.4E-125 T 29-03-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS14735 e4f0b4ceff0d0b0473e046748a271faa 299 Gene3D G3DSA:3.40.50.300 29 290 1.1E-60 T 29-03-2018 CDC59_RS14735 e4f0b4ceff0d0b0473e046748a271faa 299 SMART SM00382 57 264 1.2E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS14735 e4f0b4ceff0d0b0473e046748a271faa 299 Pfam PF00005 ABC transporter 48 198 3.5E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS14735 e4f0b4ceff0d0b0473e046748a271faa 299 SUPERFAMILY SSF52540 26 273 2.98E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS14735 e4f0b4ceff0d0b0473e046748a271faa 299 ProSitePatterns PS00211 ABC transporters family signature. 170 184 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS11285 f71d1ccb62afc29a1852a156df5d94d5 179 Pfam PF03350 Uncharacterized protein family, UPF0114 15 131 6.7E-37 T 29-03-2018 IPR005134 Uncharacterised protein family UPF0114 CDC59_RS11285 f71d1ccb62afc29a1852a156df5d94d5 179 Hamap MF_00143 UPF0114 protein YqhA [yqhA]. 1 172 91.018 T 29-03-2018 IPR020761 Uncharacterised protein family UPF0114, bacteria CDC59_RS11285 f71d1ccb62afc29a1852a156df5d94d5 179 TIGRFAM TIGR00645 HI0507: TIGR00645 family protein 11 170 7.6E-59 T 29-03-2018 IPR020761 Uncharacterised protein family UPF0114, bacteria CDC59_RS17140 fd0436017fab402aa915a9a1e996c206 685 Pfam PF07195 Flagellar hook-associated protein 2 C-terminus 586 663 9.0E-8 T 29-03-2018 IPR010809 Flagellar hook-associated 2, C-terminal GO:0007155|GO:0009288 CDC59_RS17140 fd0436017fab402aa915a9a1e996c206 685 Pfam PF07195 Flagellar hook-associated protein 2 C-terminus 258 498 4.2E-43 T 29-03-2018 IPR010809 Flagellar hook-associated 2, C-terminal GO:0007155|GO:0009288 CDC59_RS17140 fd0436017fab402aa915a9a1e996c206 685 Gene3D G3DSA:1.20.5.50 585 685 2.5E-4 T 29-03-2018 CDC59_RS17140 fd0436017fab402aa915a9a1e996c206 685 Pfam PF02465 Flagellar hook-associated protein 2 N-terminus 27 122 7.0E-22 T 29-03-2018 IPR003481 Flagellar hook-associated protein 2, N-terminal GO:0009424 CDC59_RS13670 627886cc8ed31afdd66717622d6b8fda 108 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 7 103 1.7E-24 T 29-03-2018 IPR008407 Branched-chain amino acid transport, AzlD CDC59_RS15980 388297c16877239cffb7860c9b2e4073 277 Gene3D G3DSA:1.20.1170.10 7 264 8.6E-4 T 29-03-2018 CDC59_RS16290 2e17bc8e3dcdec9f208bc7643d4c684f 171 Gene3D G3DSA:3.40.50.300 1 167 4.7E-15 T 29-03-2018 CDC59_RS16290 2e17bc8e3dcdec9f208bc7643d4c684f 171 Pfam PF00071 Ras family 39 151 4.2E-5 T 29-03-2018 IPR001806 Small GTPase superfamily GO:0003924|GO:0005525 CDC59_RS16290 2e17bc8e3dcdec9f208bc7643d4c684f 171 SUPERFAMILY SSF52540 2 121 1.28E-14 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS23235 3533c8973488355ee3b5004b782d6d76 281 SUPERFAMILY SSF54534 140 237 2.16E-13 T 29-03-2018 CDC59_RS23235 3533c8973488355ee3b5004b782d6d76 281 Pfam PF13145 PPIC-type PPIASE domain 120 251 6.6E-14 T 29-03-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 CDC59_RS23235 3533c8973488355ee3b5004b782d6d76 281 SUPERFAMILY SSF109998 33 168 4.71E-9 T 29-03-2018 IPR027304 Trigger factor/SurA domain CDC59_RS23235 3533c8973488355ee3b5004b782d6d76 281 Gene3D G3DSA:3.10.50.40 134 260 7.3E-17 T 29-03-2018 CDC59_RS12130 e739d4f201fad483231a174401e84785 88 Pfam PF13670 Peptidase propeptide and YPEB domain 4 85 1.6E-33 T 29-03-2018 IPR025711 PepSY domain CDC59_RS22555 b67fbc530f7f4936890195b084502678 448 Pfam PF13657 HipA N-terminal domain 12 111 1.2E-20 T 29-03-2018 IPR017508 HipA, N-terminal subdomain 1 CDC59_RS22555 b67fbc530f7f4936890195b084502678 448 Pfam PF07804 HipA-like C-terminal domain 159 411 1.2E-45 T 29-03-2018 IPR012893 HipA-like, C-terminal CDC59_RS22555 b67fbc530f7f4936890195b084502678 448 TIGRFAM TIGR03071 couple_hipA: HipA N-terminal domain 11 111 1.2E-25 T 29-03-2018 IPR017508 HipA, N-terminal subdomain 1 CDC59_RS17445 821ef5ea852ba78df0264e64c539fcaf 390 TIGRFAM TIGR00937 2A51: chromate efflux transporter 19 381 6.1E-138 T 29-03-2018 IPR014047 Chromate transporter, long chain CDC59_RS17445 821ef5ea852ba78df0264e64c539fcaf 390 PIRSF PIRSF004810 2 388 1.1E-86 T 29-03-2018 IPR014047 Chromate transporter, long chain CDC59_RS17445 821ef5ea852ba78df0264e64c539fcaf 390 Pfam PF02417 Chromate transporter 14 178 2.8E-32 T 29-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 CDC59_RS17445 821ef5ea852ba78df0264e64c539fcaf 390 Pfam PF02417 Chromate transporter 218 381 7.8E-34 T 29-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 CDC59_RS19655 7bcffe1fab22a21b1e14f799b89b7c22 616 PIRSF PIRSF028304 1 615 8.3E-186 T 29-03-2018 IPR010272 Type VI secretion system, TssF-like CDC59_RS19655 7bcffe1fab22a21b1e14f799b89b7c22 616 TIGRFAM TIGR03359 VI_chp_6: type VI secretion protein, TIGR03359 family 4 615 4.3E-220 T 29-03-2018 IPR010272 Type VI secretion system, TssF-like CDC59_RS19655 7bcffe1fab22a21b1e14f799b89b7c22 616 Pfam PF05947 Type VI secretion system, TssF 5 613 7.3E-206 T 29-03-2018 IPR010272 Type VI secretion system, TssF-like CDC59_RS08285 c142095b20dfdfe4da16238dbcee7b12 345 SUPERFAMILY SSF51658 23 225 2.49E-12 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CDC59_RS08285 c142095b20dfdfe4da16238dbcee7b12 345 Gene3D G3DSA:3.20.20.150 2 327 2.3E-16 T 29-03-2018 CDC59_RS14140 5b5f0bbcb97a2bcf39718759de4a9cb4 164 SUPERFAMILY SSF55961 1 147 1.37E-12 T 29-03-2018 CDC59_RS14140 5b5f0bbcb97a2bcf39718759de4a9cb4 164 Gene3D G3DSA:3.30.530.20 3 159 4.5E-10 T 29-03-2018 IPR023393 START-like domain CDC59_RS02910 de8780b796166ac4065ef758734f6f2a 140 Pfam PF07007 Lysozyme inhibitor LprI 27 129 9.7E-9 T 29-03-2018 IPR009739 Lysozyme inhibitor LprI, N-terminal CDC59_RS22550 71d3650aa7c160d1dd254b3ba2c1fd2b 88 Gene3D G3DSA:1.10.260.40 2 76 4.9E-15 T 29-03-2018 CDC59_RS22550 71d3650aa7c160d1dd254b3ba2c1fd2b 88 Pfam PF01381 Helix-turn-helix 17 67 9.3E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDC59_RS22550 71d3650aa7c160d1dd254b3ba2c1fd2b 88 SMART SM00530 15 70 9.5E-12 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CDC59_RS22550 71d3650aa7c160d1dd254b3ba2c1fd2b 88 SUPERFAMILY SSF47413 7 70 3.75E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDC59_RS13830 05488830f748cddac977a08b85d0e1ce 276 Gene3D G3DSA:3.60.20.10 1 259 3.8E-42 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CDC59_RS13830 05488830f748cddac977a08b85d0e1ce 276 SUPERFAMILY SSF56235 2 251 1.06E-43 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CDC59_RS13830 05488830f748cddac977a08b85d0e1ce 276 Pfam PF13230 Glutamine amidotransferases class-II 1 268 1.2E-127 T 29-03-2018 IPR026869 Putative glutamine amidotransferase type 2 CDC59_RS20965 36575e5a36adb33dec1ceafe2d0b844b 243 Gene3D G3DSA:3.40.630.30 17 212 3.2E-6 T 29-03-2018 CDC59_RS19990 341b9c9b0fe7081b93a6376911ff0b80 89 Pfam PF01402 Ribbon-helix-helix protein, copG family 9 46 9.2E-11 T 29-03-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 CDC59_RS19990 341b9c9b0fe7081b93a6376911ff0b80 89 SUPERFAMILY SSF47598 6 48 1.48E-9 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 CDC59_RS19990 341b9c9b0fe7081b93a6376911ff0b80 89 Gene3D G3DSA:1.10.1220.10 2 52 2.6E-6 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CDC59_RS17810 543d52aa5920579702156f122cbdf39a 368 Gene3D G3DSA:1.10.3470.10 29 367 2.0E-67 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CDC59_RS17810 543d52aa5920579702156f122cbdf39a 368 Pfam PF01032 FecCD transport family 41 363 3.1E-86 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CDC59_RS17810 543d52aa5920579702156f122cbdf39a 368 SUPERFAMILY SSF81345 26 363 1.1E-76 T 29-03-2018 IPR029022 ABC transporter, BtuC-like CDC59_RS08000 fab7ebe6581a516ba3e048320bf66370 287 SUPERFAMILY SSF55486 47 270 2.34E-37 T 29-03-2018 CDC59_RS08000 fab7ebe6581a516ba3e048320bf66370 287 Gene3D G3DSA:3.40.390.10 41 270 2.4E-21 T 29-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CDC59_RS08000 fab7ebe6581a516ba3e048320bf66370 287 Pfam PF06167 Glucose-regulated metallo-peptidase M90 11 268 2.2E-87 T 29-03-2018 IPR010384 MtfA family CDC59_RS15165 9f6ba9f28f82ac65c4762f9642698484 402 SUPERFAMILY SSF53383 6 398 4.21E-106 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CDC59_RS15165 9f6ba9f28f82ac65c4762f9642698484 402 Pfam PF00155 Aminotransferase class I and II 50 392 3.0E-42 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CDC59_RS15165 9f6ba9f28f82ac65c4762f9642698484 402 Gene3D G3DSA:3.40.640.10 57 275 1.1E-50 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CDC59_RS15165 9f6ba9f28f82ac65c4762f9642698484 402 Gene3D G3DSA:3.90.1150.10 276 401 2.8E-28 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CDC59_RS02035 3c2ec9d8b6394aab0b619cd75c6bba9b 93 Pfam PF09928 Predicted small integral membrane protein (DUF2160) 4 92 1.0E-36 T 29-03-2018 IPR018678 Protein of unknown function DUF2160, transmembrane CDC59_RS21975 854cffb9c55d8556a9d738dfce6cc0fc 455 Pfam PF01554 MatE 248 409 5.7E-27 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CDC59_RS21975 854cffb9c55d8556a9d738dfce6cc0fc 455 Pfam PF01554 MatE 19 178 3.3E-35 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CDC59_RS21975 854cffb9c55d8556a9d738dfce6cc0fc 455 TIGRFAM TIGR00797 matE: MATE efflux family protein 19 420 7.4E-76 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CDC59_RS21975 854cffb9c55d8556a9d738dfce6cc0fc 455 PIRSF PIRSF006603 5 453 4.2E-99 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CDC59_RS07035 93b6f82d90c7d77d95288207f11277a1 391 Pfam PF05762 VWA domain containing CoxE-like protein 185 273 1.8E-7 T 29-03-2018 IPR008912 Uncharacterised protein family CoxE-like CDC59_RS01005 7e5e61a5b0095fafaacccb4e82c8a911 218 Gene3D G3DSA:3.90.1240.10 2 218 5.5E-34 T 29-03-2018 CDC59_RS01005 7e5e61a5b0095fafaacccb4e82c8a911 218 Pfam PF14891 Effector protein 16 218 9.3E-36 T 29-03-2018 IPR028208 Effector protein NleD-like CDC59_RS12170 00abb46d2b3b08111d333f6909bb1a89 205 SUPERFAMILY SSF47240 61 204 9.7E-39 T 29-03-2018 IPR009078 Ferritin-like superfamily CDC59_RS12170 00abb46d2b3b08111d333f6909bb1a89 205 Gene3D G3DSA:1.20.1260.10 58 196 6.3E-25 T 29-03-2018 IPR012347 Ferritin-related CDC59_RS12170 00abb46d2b3b08111d333f6909bb1a89 205 Pfam PF13668 Ferritin-like domain 62 195 6.4E-36 T 29-03-2018 CDC59_RS19495 31ce49b1edf520aec97bf63b7095dc3e 200 Pfam PF07040 Protein of unknown function (DUF1326) 11 190 6.6E-55 T 29-03-2018 IPR009758 Protein of unknown function DUF1326 CDC59_RS20820 5a31ea440f7788b66cf2e631957de873 387 Gene3D G3DSA:3.40.50.2000 177 352 2.8E-22 T 29-03-2018 CDC59_RS20820 5a31ea440f7788b66cf2e631957de873 387 Pfam PF00534 Glycosyl transferases group 1 186 345 8.0E-10 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CDC59_RS20820 5a31ea440f7788b66cf2e631957de873 387 SUPERFAMILY SSF53756 120 367 1.78E-31 T 29-03-2018 CDC59_RS08750 0b9796aeafa4b08295fd302e58b09edd 556 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 73 235 3.9E-16 T 29-03-2018 CDC59_RS20975 887f2e832fa548c4df316a4e060c7b2b 254 Pfam PF10118 Predicted metal-dependent hydrolase 12 239 2.2E-33 T 29-03-2018 IPR016516 Uncharacterised conserved protein UCP07580 CDC59_RS08610 a76cccb7e494b3a4aea0b2d92437a667 372 Pfam PF16113 Enoyl-CoA hydratase/isomerase 28 356 2.3E-122 T 29-03-2018 IPR032259 Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type GO:0003860 Reactome: R-HSA-70895 CDC59_RS08610 a76cccb7e494b3a4aea0b2d92437a667 372 SUPERFAMILY SSF52096 271 339 3.45E-66 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CDC59_RS08610 a76cccb7e494b3a4aea0b2d92437a667 372 SUPERFAMILY SSF52096 15 206 3.45E-66 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CDC59_RS08610 a76cccb7e494b3a4aea0b2d92437a667 372 Gene3D G3DSA:3.90.226.10 2 350 1.1E-87 T 29-03-2018 CDC59_RS17740 4e022ad04150479a404500c328e5f180 315 Pfam PF13557 Putative MetA-pathway of phenol degradation 59 311 3.8E-55 T 29-03-2018 IPR025737 MetA-pathway of phenol degradation, putative CDC59_RS06515 496b20944c484e60a0d4234cfdfce495 213 Pfam PF13590 Domain of unknown function (DUF4136) 48 192 1.2E-14 T 29-03-2018 IPR025411 Domain of unknown function DUF4136 CDC59_RS11310 8dfabf0bd30864c2a75a557a10b0ea67 118 Gene3D G3DSA:1.10.10.10 1 96 5.4E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS11310 8dfabf0bd30864c2a75a557a10b0ea67 118 SMART SM00418 10 84 4.8E-14 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CDC59_RS11310 8dfabf0bd30864c2a75a557a10b0ea67 118 SUPERFAMILY SSF46785 8 102 1.63E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS11310 8dfabf0bd30864c2a75a557a10b0ea67 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 12 27 4.1E-7 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CDC59_RS11310 8dfabf0bd30864c2a75a557a10b0ea67 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 44 59 4.1E-7 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CDC59_RS11310 8dfabf0bd30864c2a75a557a10b0ea67 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 59 74 4.1E-7 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CDC59_RS11310 8dfabf0bd30864c2a75a557a10b0ea67 118 Pfam PF12840 Helix-turn-helix domain 11 68 2.8E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS05760 abec17e43eba4a908a2bda134f9c982f 247 Gene3D G3DSA:3.40.50.300 46 210 2.1E-23 T 29-03-2018 CDC59_RS05760 abec17e43eba4a908a2bda134f9c982f 247 Pfam PF00625 Guanylate kinase 57 172 2.6E-12 T 29-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CDC59_RS05760 abec17e43eba4a908a2bda134f9c982f 247 SUPERFAMILY SSF52540 55 218 2.72E-21 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS05760 abec17e43eba4a908a2bda134f9c982f 247 SMART SM00072 53 242 2.5E-4 T 29-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CDC59_RS07725 91688854af08ff10f7ae48034577bbb0 129 Pfam PF04134 Protein of unknown function, DUF393 3 112 2.9E-32 T 29-03-2018 IPR007263 Protein of unknown function DUF393 CDC59_RS07725 91688854af08ff10f7ae48034577bbb0 129 Gene3D G3DSA:3.40.47.10 8 89 0.0012 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CDC59_RS23395 a5b3e5fa8660bdcbf0bc0a6b029b4234 169 Gene3D G3DSA:3.90.20.10 1 146 0.0011 T 29-03-2018 CDC59_RS10810 464c803f4a67a90a14911365c99925b2 130 Pfam PF09842 Predicted membrane protein (DUF2069) 18 118 1.7E-35 T 29-03-2018 IPR018643 Protein of unknown function DUF2069, membrane CDC59_RS03905 3ba12c5432b86ef840dc902eecd86322 1070 Gene3D G3DSA:3.40.50.410 38 325 5.1E-16 T 29-03-2018 IPR002035 von Willebrand factor, type A CDC59_RS03905 3ba12c5432b86ef840dc902eecd86322 1070 Pfam PF05567 Neisseria PilC beta-propeller domain 581 823 9.5E-13 T 29-03-2018 IPR008707 PilC beta-propeller domain CDC59_RS20815 990e59b30936bc66f86acffbafc96fcc 170 SUPERFAMILY SSF51161 5 169 1.52E-39 T 29-03-2018 IPR011004 Trimeric LpxA-like CDC59_RS20815 990e59b30936bc66f86acffbafc96fcc 170 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 116 150 1.1E-10 T 29-03-2018 IPR001451 Hexapeptide repeat CDC59_RS20815 990e59b30936bc66f86acffbafc96fcc 170 Gene3D G3DSA:2.160.10.10 3 170 7.8E-37 T 29-03-2018 CDC59_RS04665 75deacdcd24943b251b3f6981ede02ae 207 Pfam PF13681 Type IV pilus assembly protein PilX C-term 110 202 8.8E-16 T 29-03-2018 IPR025205 PilX/PilW C-terminal domain CDC59_RS18275 8f0836b99740a5ab7983a2e967f6c967 261 Pfam PF00005 ABC transporter 31 170 6.3E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS18275 8f0836b99740a5ab7983a2e967f6c967 261 SMART SM00382 37 220 4.6E-19 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS18275 8f0836b99740a5ab7983a2e967f6c967 261 Gene3D G3DSA:3.40.50.300 6 230 6.6E-59 T 29-03-2018 CDC59_RS18275 8f0836b99740a5ab7983a2e967f6c967 261 SUPERFAMILY SSF52540 9 229 4.33E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS18275 8f0836b99740a5ab7983a2e967f6c967 261 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS23775 94c1b42761f8b88b02f8916bd6960929 278 Pfam PF02673 Bacitracin resistance protein BacA 7 271 3.0E-56 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CDC59_RS06750 fd63a1019d35dfb001a83ec774c84d70 104 Gene3D G3DSA:3.30.70.790 1 73 1.3E-13 T 29-03-2018 CDC59_RS17435 05f3bab8bab970e9070f5ba8b82ad500 90 Pfam PF02583 Metal-sensitive transcriptional repressor 7 86 2.9E-20 T 29-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 CDC59_RS07655 7851b375f7bff2e498ca6aeb786e020a 320 Pfam PF04168 A predicted alpha-helical domain with a conserved ER motif. 1 314 6.3E-105 T 29-03-2018 IPR007296 Domain of unknown function DUF403 CDC59_RS07265 11e38abafdda0ea27b311ae15e13625b 138 Pfam PF00355 Rieske [2Fe-2S] domain 39 100 1.0E-6 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CDC59_RS07265 11e38abafdda0ea27b311ae15e13625b 138 Gene3D G3DSA:2.102.10.10 3 131 1.7E-19 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CDC59_RS07265 11e38abafdda0ea27b311ae15e13625b 138 SUPERFAMILY SSF50022 9 117 1.96E-20 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CDC59_RS05500 7bee657832b845772bad02345a416453 106 Pfam PF06305 Lipopolysaccharide assembly protein A domain 23 84 2.4E-14 T 29-03-2018 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 CDC59_RS08135 637a663b9bd47b946962552c0e98c7d5 233 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 24 225 4.5E-41 T 29-03-2018 IPR006214 Bax inhibitor 1-related CDC59_RS04705 cd34adff7872cb7675699124f73f14dd 206 TIGRFAM TIGR02523 type_IV_pilV: type IV pilus modification protein PilV 9 166 2.8E-50 T 29-03-2018 IPR013362 Pilus modification type IV, PilV CDC59_RS05060 ed45aaffdf2965c385b44acd8567653d 350 Gene3D G3DSA:3.40.50.1580 33 316 7.4E-14 T 29-03-2018 CDC59_RS05060 ed45aaffdf2965c385b44acd8567653d 350 PIRSF PIRSF013171 4 350 1.2E-159 T 29-03-2018 IPR009486 Purine nucleoside permease GO:0055085 CDC59_RS05060 ed45aaffdf2965c385b44acd8567653d 350 Pfam PF06516 Purine nucleoside permease (NUP) 38 347 3.3E-123 T 29-03-2018 IPR009486 Purine nucleoside permease GO:0055085 CDC59_RS18425 54f09db091c9d44823b4ac401ceda847 365 Gene3D G3DSA:3.40.50.1110 82 365 4.5E-17 T 29-03-2018 CDC59_RS18425 54f09db091c9d44823b4ac401ceda847 365 SUPERFAMILY SSF52266 82 158 5.18E-17 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain CDC59_RS18425 54f09db091c9d44823b4ac401ceda847 365 SUPERFAMILY SSF52266 236 268 5.18E-17 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain CDC59_RS18425 54f09db091c9d44823b4ac401ceda847 365 SUPERFAMILY SSF52266 296 363 5.18E-17 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain CDC59_RS22340 36a7c54b6effcaab4adeb8971932c9dc 157 SUPERFAMILY SSF51182 35 152 2.44E-12 T 29-03-2018 IPR011051 RmlC-like cupin domain CDC59_RS22340 36a7c54b6effcaab4adeb8971932c9dc 157 Gene3D G3DSA:2.60.120.10 26 152 1.4E-8 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CDC59_RS09070 8a0972235b17cc032bec925c476bc58a 172 Gene3D G3DSA:2.40.320.10 1 169 9.1E-22 T 29-03-2018 CDC59_RS09070 8a0972235b17cc032bec925c476bc58a 172 SMART SM01118 2 169 4.2E-12 T 29-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 CDC59_RS09070 8a0972235b17cc032bec925c476bc58a 172 ProDom PD009560 CYCLASE ADENYLATE CYCLASE ADENYLYL CYAB LYASE CLASS CYAB-TYPE THERMOPHILIC MJ0240 33 133 0.001 T 29-03-2018 CDC59_RS09070 8a0972235b17cc032bec925c476bc58a 172 Pfam PF01928 CYTH domain 3 160 1.0E-19 T 29-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 CDC59_RS09070 8a0972235b17cc032bec925c476bc58a 172 SUPERFAMILY SSF55154 3 167 4.09E-34 T 29-03-2018 IPR033469 CYTH-like domain Reactome: R-HSA-196819 CDC59_RS01160 6dfc6bb6b51ef6a79515f69e54303f66 272 Pfam PF04972 BON domain 133 198 8.7E-13 T 29-03-2018 IPR007055 BON domain CDC59_RS01160 6dfc6bb6b51ef6a79515f69e54303f66 272 Pfam PF04972 BON domain 75 123 3.2E-11 T 29-03-2018 IPR007055 BON domain CDC59_RS01160 6dfc6bb6b51ef6a79515f69e54303f66 272 SMART SM00749 60 123 5.7E-7 T 29-03-2018 IPR014004 Transport-associated and nodulation domain, bacteria CDC59_RS01160 6dfc6bb6b51ef6a79515f69e54303f66 272 SMART SM00749 138 201 4.6E-12 T 29-03-2018 IPR014004 Transport-associated and nodulation domain, bacteria CDC59_RS04565 eb1c8c5b6002d1f2e575e1396e59ee43 293 Pfam PF02673 Bacitracin resistance protein BacA 9 279 1.8E-88 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CDC59_RS04565 eb1c8c5b6002d1f2e575e1396e59ee43 293 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 9 277 1.4E-70 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CDC59_RS04565 eb1c8c5b6002d1f2e575e1396e59ee43 293 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 4 284 18.238 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CDC59_RS22450 ccfdaa6ae4693280ace291a468e1c424 203 Gene3D G3DSA:1.10.760.10 28 188 3.4E-17 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS22450 ccfdaa6ae4693280ace291a468e1c424 203 SUPERFAMILY SSF46626 15 184 4.6E-21 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS22450 ccfdaa6ae4693280ace291a468e1c424 203 Pfam PF02433 Cytochrome C oxidase, mono-heme subunit/FixO 12 143 4.0E-37 T 29-03-2018 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO CDC59_RS13360 7952961a2921cabb33d80ca414f398f3 107 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 6 104 8.8E-27 T 29-03-2018 IPR008407 Branched-chain amino acid transport, AzlD CDC59_RS07945 c2c7192d7c85193d32556e707ce9834e 319 SUPERFAMILY SSF52151 2 307 2.79E-61 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CDC59_RS07945 c2c7192d7c85193d32556e707ce9834e 319 Gene3D G3DSA:3.40.1090.10 40 263 4.5E-50 T 29-03-2018 CDC59_RS07945 c2c7192d7c85193d32556e707ce9834e 319 Pfam PF01734 Patatin-like phospholipase 55 214 4.9E-28 T 29-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 CDC59_RS01335 3a1f5ec41fa8b5812a66b3a95b504f67 171 Pfam PF11994 Protein of unknown function (DUF3489) 104 170 6.6E-30 T 29-03-2018 IPR021880 Protein of unknown function DUF3489 CDC59_RS14925 bf9790f72a205c37642d9eb87167a368 612 PIRSF PIRSF000719 7 593 4.5E-284 T 29-03-2018 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 CDC59_RS14925 bf9790f72a205c37642d9eb87167a368 612 ProDom PD043552 KINASE KINASE/PHOSPHATASE ISOCITRATE DEHYDROGENASE 3.1.3.- IDH TRANSFERASE IDHK/P HYDROLASE ENZYME 16 591 0.0 T 29-03-2018 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 CDC59_RS14925 bf9790f72a205c37642d9eb87167a368 612 Hamap MF_00747 Isocitrate dehydrogenase kinase/phosphatase [aceK]. 8 588 44.757 T 29-03-2018 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 CDC59_RS14925 bf9790f72a205c37642d9eb87167a368 612 Pfam PF06315 Isocitrate dehydrogenase kinase/phosphatase (AceK) 16 583 2.0E-254 T 29-03-2018 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 CDC59_RS16660 21e2c722d1f24b15ff4efb1bf6a0cf77 128 Pfam PF13665 Domain of unknown function (DUF4150) 22 127 1.8E-32 T 29-03-2018 IPR025425 Domain of unknown function DUF4150 CDC59_RS00620 52c0d9c2e7a6672a2c6c0f7ae3508a61 319 Pfam PF10030 Uncharacterized protein conserved in bacteria (DUF2272) 179 297 1.1E-19 T 29-03-2018 IPR019262 Domain of unknown function DUF2272 CDC59_RS04950 1db2c223f58b0ab0bce7ee11025db1a7 221 Gene3D G3DSA:3.40.30.10 1 218 3.0E-32 T 29-03-2018 CDC59_RS04950 1db2c223f58b0ab0bce7ee11025db1a7 221 Pfam PF01323 DSBA-like thioredoxin domain 5 188 1.5E-14 T 29-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 CDC59_RS04950 1db2c223f58b0ab0bce7ee11025db1a7 221 SUPERFAMILY SSF52833 1 217 1.28E-29 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS03010 3a9b6f97283ca5c5a094603d0d51936b 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 301 1.7E-32 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS03010 3a9b6f97283ca5c5a094603d0d51936b 304 SUPERFAMILY SSF161098 95 285 1.44E-30 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS03010 3a9b6f97283ca5c5a094603d0d51936b 304 Gene3D G3DSA:1.10.3720.10 18 292 5.7E-47 T 29-03-2018 CDC59_RS03010 3a9b6f97283ca5c5a094603d0d51936b 304 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 16 60 8.7E-12 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CDC59_RS16355 28d3bed26cb6b422c50cdfb13fb0a174 419 Pfam PF15984 Bacterial collagen, middle region 125 321 5.6E-66 T 29-03-2018 IPR031929 Bacterial collagen-like protein, middle domain CDC59_RS16355 28d3bed26cb6b422c50cdfb13fb0a174 419 Gene3D G3DSA:1.20.120.20 177 326 0.0029 T 29-03-2018 CDC59_RS21130 84346472391848f6e901f7f134d9910d 292 Pfam PF05114 Protein of unknown function (DUF692) 12 276 2.7E-94 T 29-03-2018 IPR007801 Uncharacterised protein family UPF0276 CDC59_RS21130 84346472391848f6e901f7f134d9910d 292 Gene3D G3DSA:3.20.20.150 8 288 4.4E-69 T 29-03-2018 CDC59_RS19570 1aa06ea02af5824eeb815673d78958ef 408 Pfam PF04116 Fatty acid hydroxylase superfamily 231 364 4.5E-29 T 29-03-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 CDC59_RS21120 7a01ca0f67079bedf1572751b6a78e90 83 Pfam PF00816 H-NS histone family 10 75 7.1E-11 T 29-03-2018 IPR001801 Histone-like protein H-NS GO:0003677|GO:0005622|GO:0006355 CDC59_RS21120 7a01ca0f67079bedf1572751b6a78e90 83 Gene3D G3DSA:4.10.430.10 45 82 3.3E-13 T 29-03-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 CDC59_RS21120 7a01ca0f67079bedf1572751b6a78e90 83 SUPERFAMILY SSF81273 42 82 1.57E-10 T 29-03-2018 CDC59_RS09435 8d5425158e6303ac6db0058f530a12f3 478 SUPERFAMILY SSF53720 5 470 3.53E-160 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CDC59_RS09435 8d5425158e6303ac6db0058f530a12f3 478 Pfam PF00171 Aldehyde dehydrogenase family 13 469 5.2E-165 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CDC59_RS09435 8d5425158e6303ac6db0058f530a12f3 478 Gene3D G3DSA:3.40.605.10 2 262 4.3E-92 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CDC59_RS09435 8d5425158e6303ac6db0058f530a12f3 478 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 244 251 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CDC59_RS09435 8d5425158e6303ac6db0058f530a12f3 478 Gene3D G3DSA:3.40.309.10 263 456 6.1E-68 T 29-03-2018 CDC59_RS18665 9c1be9165adb4e109cdb1a761660f9f8 473 SUPERFAMILY SSF56954 69 457 3.27E-64 T 29-03-2018 CDC59_RS18665 9c1be9165adb4e109cdb1a761660f9f8 473 SUPERFAMILY SSF56954 10 39 3.27E-64 T 29-03-2018 CDC59_RS18665 9c1be9165adb4e109cdb1a761660f9f8 473 Gene3D G3DSA:1.20.1600.10 30 461 2.2E-54 T 29-03-2018 CDC59_RS18665 9c1be9165adb4e109cdb1a761660f9f8 473 Pfam PF02321 Outer membrane efflux protein 78 251 4.5E-6 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CDC59_RS18665 9c1be9165adb4e109cdb1a761660f9f8 473 Pfam PF02321 Outer membrane efflux protein 278 453 2.3E-15 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CDC59_RS17520 515587f3c146e67c5b91024fce4e8e16 245 SMART SM00062 16 236 1.2E-22 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CDC59_RS17520 515587f3c146e67c5b91024fce4e8e16 245 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 20 232 7.6E-20 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CDC59_RS17520 515587f3c146e67c5b91024fce4e8e16 245 Gene3D G3DSA:3.40.190.10 6 114 2.1E-13 T 29-03-2018 CDC59_RS17520 515587f3c146e67c5b91024fce4e8e16 245 SUPERFAMILY SSF53850 17 233 1.09E-31 T 29-03-2018 CDC59_RS17520 515587f3c146e67c5b91024fce4e8e16 245 Gene3D G3DSA:3.40.190.10 115 194 8.7E-11 T 29-03-2018 CDC59_RS21440 dcc19465087c6ff304e146416f623b62 538 Pfam PF09977 Putative Tad-like Flp pilus-assembly 43 127 1.6E-7 T 29-03-2018 IPR018705 Domain of unknown function DUF2134, membrane CDC59_RS15135 208a1f547a3522900457142e8fac86c1 119 Pfam PF04248 Domain of unknown function (DUF427) 19 110 1.9E-32 T 29-03-2018 IPR007361 Domain of unknown function DUF427 CDC59_RS04305 28db1590ea74c252ce5216c44ec2b9c2 345 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 15 61 1.2E-10 T 29-03-2018 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal CDC59_RS14660 a0526f4be538392040415f83eb87df30 119 Pfam PF11142 Protein of unknown function (DUF2917) 10 71 1.9E-17 T 29-03-2018 IPR021317 Protein of unknown function DUF2917 CDC59_RS21785 26c161693de765c548aad559ca8ecea3 424 Gene3D G3DSA:1.20.1250.20 13 209 9.9E-20 T 29-03-2018 CDC59_RS21785 26c161693de765c548aad559ca8ecea3 424 Gene3D G3DSA:1.20.1250.20 224 422 2.2E-11 T 29-03-2018 CDC59_RS21785 26c161693de765c548aad559ca8ecea3 424 Pfam PF05977 Transmembrane secretion effector 18 404 1.3E-38 T 29-03-2018 IPR010290 Transmembrane secretion effector CDC59_RS21785 26c161693de765c548aad559ca8ecea3 424 SUPERFAMILY SSF103473 26 415 8.11E-39 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS13575 835553fa8cc22a29d3853811eed7aa2e 330 SUPERFAMILY SSF52540 117 296 3.06E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS13575 835553fa8cc22a29d3853811eed7aa2e 330 Pfam PF02562 PhoH-like protein 119 321 2.2E-92 T 29-03-2018 IPR003714 PhoH-like protein GO:0005524 CDC59_RS13575 835553fa8cc22a29d3853811eed7aa2e 330 Gene3D G3DSA:3.40.50.300 114 321 7.2E-29 T 29-03-2018 CDC59_RS17820 3c0b0fdeab0d8a7c6ff11f91e1bb8956 379 SUPERFAMILY SSF144064 27 361 3.04E-119 T 29-03-2018 CDC59_RS17820 3c0b0fdeab0d8a7c6ff11f91e1bb8956 379 Gene3D G3DSA:3.40.1570.10 23 195 4.8E-50 T 29-03-2018 CDC59_RS17820 3c0b0fdeab0d8a7c6ff11f91e1bb8956 379 Gene3D G3DSA:3.40.1570.10 207 364 6.9E-50 T 29-03-2018 CDC59_RS17820 3c0b0fdeab0d8a7c6ff11f91e1bb8956 379 Pfam PF05171 Haemin-degrading HemS.ChuX domain 229 361 2.4E-39 T 29-03-2018 IPR007845 Haemin-degrading HemS/ChuX domain GO:0006826 CDC59_RS17820 3c0b0fdeab0d8a7c6ff11f91e1bb8956 379 Pfam PF05171 Haemin-degrading HemS.ChuX domain 46 176 1.1E-35 T 29-03-2018 IPR007845 Haemin-degrading HemS/ChuX domain GO:0006826 CDC59_RS05145 047e63de66560e18cde1a6b0489560c7 120 Pfam PF01638 HxlR-like helix-turn-helix 27 110 4.5E-22 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type CDC59_RS05145 047e63de66560e18cde1a6b0489560c7 120 SUPERFAMILY SSF46785 13 117 7.12E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS05145 047e63de66560e18cde1a6b0489560c7 120 Gene3D G3DSA:1.10.10.10 6 117 3.2E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CDC59_RS01785 d71e67c6e6f4f6a0bb93b8ddabbd2771 231 Pfam PF00583 Acetyltransferase (GNAT) family 84 166 3.7E-7 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CDC59_RS01785 d71e67c6e6f4f6a0bb93b8ddabbd2771 231 Gene3D G3DSA:3.40.630.30 27 195 3.7E-18 T 29-03-2018 CDC59_RS01785 d71e67c6e6f4f6a0bb93b8ddabbd2771 231 SUPERFAMILY SSF55729 32 170 1.08E-17 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CDC59_RS08700 58dee2af61a73422e1e50dc0a4b72746 244 Gene3D G3DSA:3.90.1720.10 56 187 3.9E-35 T 29-03-2018 CDC59_RS08700 58dee2af61a73422e1e50dc0a4b72746 244 SUPERFAMILY SSF54001 58 180 1.65E-39 T 29-03-2018 CDC59_RS08700 58dee2af61a73422e1e50dc0a4b72746 244 Pfam PF00877 NlpC/P60 family 71 178 1.8E-27 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CDC59_RS11995 632303631a7ba2e7295393ae58832c55 456 Pfam PF03432 Relaxase/Mobilisation nuclease domain 74 257 7.6E-7 T 29-03-2018 IPR005094 Endonuclease relaxase, MobA/VirD2 CDC59_RS23705 75d246f3652b998383141da9944ee983 398 Gene3D G3DSA:1.10.3470.10 50 391 7.9E-29 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CDC59_RS23705 75d246f3652b998383141da9944ee983 398 Pfam PF02653 Branched-chain amino acid transport system / permease component 61 387 5.6E-44 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CDC59_RS07055 550c8431939e0fcb170e63dc00ade779 128 SUPERFAMILY SSF46626 4 121 2.68E-17 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS07055 550c8431939e0fcb170e63dc00ade779 128 Gene3D G3DSA:1.10.760.10 13 124 3.3E-15 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS07055 550c8431939e0fcb170e63dc00ade779 128 Pfam PF00034 Cytochrome c 25 120 5.6E-10 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CDC59_RS05050 1fcee71829aeb7d94449374ecb9ffa5e 346 Pfam PF06250 Protein of unknown function (DUF1016) 13 330 1.2E-109 T 29-03-2018 IPR009362 Protein of unknown function DUF1016 CDC59_RS02730 4daec78f85fa51fc2bd0fbcd99520107 626 Pfam PF01019 Gamma-glutamyltranspeptidase 88 621 5.0E-136 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CDC59_RS02730 4daec78f85fa51fc2bd0fbcd99520107 626 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 440 458 4.3E-59 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CDC59_RS02730 4daec78f85fa51fc2bd0fbcd99520107 626 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 524 541 4.3E-59 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CDC59_RS02730 4daec78f85fa51fc2bd0fbcd99520107 626 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 286 302 4.3E-59 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CDC59_RS02730 4daec78f85fa51fc2bd0fbcd99520107 626 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 168 186 4.3E-59 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CDC59_RS02730 4daec78f85fa51fc2bd0fbcd99520107 626 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 186 205 4.3E-59 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CDC59_RS02730 4daec78f85fa51fc2bd0fbcd99520107 626 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 498 513 4.3E-59 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CDC59_RS02730 4daec78f85fa51fc2bd0fbcd99520107 626 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 316 335 4.3E-59 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CDC59_RS02730 4daec78f85fa51fc2bd0fbcd99520107 626 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 95 120 4.3E-59 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CDC59_RS02730 4daec78f85fa51fc2bd0fbcd99520107 626 SUPERFAMILY SSF56235 64 625 3.47E-151 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CDC59_RS12540 eb882a1617450e7a51803a9f85f74754 378 Gene3D G3DSA:1.10.3470.10 7 354 8.7E-44 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CDC59_RS12540 eb882a1617450e7a51803a9f85f74754 378 Pfam PF02653 Branched-chain amino acid transport system / permease component 42 350 2.0E-49 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CDC59_RS03655 6c0713df728f724b77cee1b59d17e97a 380 Pfam PF07786 Protein of unknown function (DUF1624) 7 216 1.2E-14 T 29-03-2018 IPR012429 Domain of unknown function DUF1624 Reactome: R-HSA-2024096|Reactome: R-HSA-6798695 CDC59_RS15830 fad1150e476499d9b9af8aaf540d5023 346 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 9 276 9.5E-48 T 29-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 CDC59_RS15830 fad1150e476499d9b9af8aaf540d5023 346 Pfam PF04085 rod shape-determining protein MreC 127 273 2.4E-36 T 29-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 CDC59_RS19120 b7ddba147ad2f0841966eec1639a7686 1370 Gene3D G3DSA:3.40.50.1980 631 1097 4.7E-5 T 29-03-2018 CDC59_RS19120 b7ddba147ad2f0841966eec1639a7686 1370 Pfam PF02514 CobN/Magnesium Chelatase 121 1346 0.0 T 29-03-2018 IPR003672 CobN/magnesium chelatase GO:0009058 CDC59_RS05705 19fa4c09e8da8baff9dbe3c3aa9c68d6 96 Gene3D G3DSA:1.10.260.40 2 93 2.0E-5 T 29-03-2018 CDC59_RS05705 19fa4c09e8da8baff9dbe3c3aa9c68d6 96 SUPERFAMILY SSF47413 13 60 9.38E-6 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CDC59_RS12825 dc3572ef90eb8b39cdb3cfb0b8311b22 89 Gene3D G3DSA:1.10.357.10 2 84 7.2E-4 T 29-03-2018 CDC59_RS13730 17b17ddef83440816cb438a1597a2edd 378 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 46 367 4.2E-48 T 29-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CDC59_RS13730 17b17ddef83440816cb438a1597a2edd 378 SUPERFAMILY SSF51695 41 373 1.36E-79 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CDC59_RS13730 17b17ddef83440816cb438a1597a2edd 378 Gene3D G3DSA:3.20.20.190 39 374 1.7E-69 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CDC59_RS00220 c7a10a162d533daf4d5386476964a360 78 Pfam PF14375 Cysteine-rich CWC 19 67 5.5E-8 T 29-03-2018 IPR032720 Cysteine-rich CWC CDC59_RS20760 c0982b2075f9276538b84535a5c1dbc7 570 Gene3D G3DSA:3.40.190.10 2 180 2.0E-5 T 29-03-2018 CDC59_RS01720 cc6e866e644b93304c80d373b3c0bf6e 354 Pfam PF03934 Type II secretion system (T2SS), protein K 38 334 5.9E-78 T 29-03-2018 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 CDC59_RS01720 cc6e866e644b93304c80d373b3c0bf6e 354 Gene3D G3DSA:1.10.40.60 244 304 1.3E-10 T 29-03-2018 CDC59_RS01720 cc6e866e644b93304c80d373b3c0bf6e 354 SUPERFAMILY SSF158544 124 240 5.23E-13 T 29-03-2018 CDC59_RS01720 cc6e866e644b93304c80d373b3c0bf6e 354 PIRSF PIRSF002786 8 352 3.3E-74 T 29-03-2018 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 CDC59_RS01720 cc6e866e644b93304c80d373b3c0bf6e 354 Gene3D G3DSA:3.30.1300.30 34 183 1.1E-30 T 29-03-2018 CDC59_RS01720 cc6e866e644b93304c80d373b3c0bf6e 354 SUPERFAMILY SSF54523 46 123 2.35E-5 T 29-03-2018 CDC59_RS01720 cc6e866e644b93304c80d373b3c0bf6e 354 SUPERFAMILY SSF54523 307 335 2.35E-5 T 29-03-2018 CDC59_RS07160 e55896f06a836e65295f77de209d01f8 66 Pfam PF12088 Protein of unknown function (DUF3565) 6 62 2.5E-30 T 29-03-2018 IPR021948 Protein of unknown function DUF3565 CDC59_RS02030 49d7202d9718f8d7d78a306bc9f29466 578 SUPERFAMILY SSF53850 70 519 4.28E-63 T 29-03-2018 CDC59_RS02030 49d7202d9718f8d7d78a306bc9f29466 578 Pfam PF01547 Bacterial extracellular solute-binding protein 89 426 1.4E-11 T 29-03-2018 IPR006059 Solute-binding family 1 GO:0006810 CDC59_RS02030 49d7202d9718f8d7d78a306bc9f29466 578 Gene3D G3DSA:3.40.190.10 192 529 6.3E-31 T 29-03-2018 CDC59_RS02030 49d7202d9718f8d7d78a306bc9f29466 578 PIRSF PIRSF035859 1 577 3.2E-297 T 29-03-2018 IPR014597 ABC transporter, periplasmic substrate-binding protein, predicted GO:0005215 CDC59_RS19560 e8a96ada3cc80ceb6a15f7e4ae7b2d67 413 SUPERFAMILY SSF103473 15 397 3.27E-11 T 29-03-2018 IPR020846 Major facilitator superfamily domain CDC59_RS19560 e8a96ada3cc80ceb6a15f7e4ae7b2d67 413 Pfam PF05977 Transmembrane secretion effector 88 304 7.0E-5 T 29-03-2018 IPR010290 Transmembrane secretion effector CDC59_RS19560 e8a96ada3cc80ceb6a15f7e4ae7b2d67 413 Gene3D G3DSA:1.20.1250.20 5 195 0.075 T 29-03-2018 CDC59_RS19560 e8a96ada3cc80ceb6a15f7e4ae7b2d67 413 Gene3D G3DSA:1.20.1250.20 214 405 0.0056 T 29-03-2018 CDC59_RS14875 0c5c1ec34bfc102f96b51813c3e79679 106 Pfam PF08895 Domain of unknown function (DUF1840) 1 104 1.0E-28 T 29-03-2018 IPR014991 Protein of unknown function DUF1840 CDC59_RS15005 3a99d8f7fe775dfdbee6800e4b37fe5d 140 Pfam PF10908 Protein of unknown function (DUF2778) 10 127 3.5E-32 T 29-03-2018 IPR021225 Protein of unknown function DUF2778 CDC59_RS21455 8c34c11d69520fba4b78af3e5ef9a3c7 326 Pfam PF00482 Type II secretion system (T2SS), protein F 179 305 1.9E-13 T 29-03-2018 IPR018076 Type II secretion system F domain CDC59_RS20825 00a1d7f7911b0325603c0c362ef1867b 418 Pfam PF14897 EpsG family 87 395 2.0E-24 T 29-03-2018 CDC59_RS10605 c979df3ffeb6cbbc87caedb6d1d59e0c 1385 Gene3D G3DSA:1.20.120.560 332 756 0.33 T 29-03-2018 CDC59_RS00335 fb2c0edc90143c17f0a6ffd3aaf57688 377 Pfam PF13503 Domain of unknown function (DUF4123) 55 200 9.2E-15 T 29-03-2018 IPR025391 Domain of unknown function DUF4123 CDC59_RS14195 5c07050cbe2b38aa0cdaf783d44e0641 134 Pfam PF13467 Ribbon-helix-helix domain 16 83 1.6E-24 T 29-03-2018 IPR027373 Ribbon-helix-helix domain CDC59_RS14195 5c07050cbe2b38aa0cdaf783d44e0641 134 Gene3D G3DSA:1.10.3990.20 11 95 2.4E-32 T 29-03-2018 CDC59_RS07335 51f1a1657efabb52a8589d56abef33d0 210 Pfam PF03872 Anti sigma-E protein RseA, N-terminal domain 15 99 1.4E-19 T 29-03-2018 IPR005572 Anti sigma-E protein RseA, N-terminal GO:0016989 CDC59_RS07335 51f1a1657efabb52a8589d56abef33d0 210 SUPERFAMILY SSF89069 14 81 4.18E-14 T 29-03-2018 IPR005572 Anti sigma-E protein RseA, N-terminal GO:0016989 CDC59_RS06630 5ae3d7d73f73bfff9b301eb72e4af98e 345 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 15 337 8.7E-113 T 29-03-2018 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 CDC59_RS06630 5ae3d7d73f73bfff9b301eb72e4af98e 345 Pfam PF00962 Adenosine/AMP deaminase 14 334 6.6E-71 T 29-03-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 CDC59_RS06630 5ae3d7d73f73bfff9b301eb72e4af98e 345 Hamap MF_01962 Adenine deaminase. 10 326 83.864 T 29-03-2018 IPR028892 Adenine deaminase type 2 GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 CDC59_RS06630 5ae3d7d73f73bfff9b301eb72e4af98e 345 Gene3D G3DSA:3.20.20.140 4 345 2.2E-81 T 29-03-2018 CDC59_RS06630 5ae3d7d73f73bfff9b301eb72e4af98e 345 SUPERFAMILY SSF51556 10 343 1.76E-86 T 29-03-2018 IPR032466 Metal-dependent hydrolase CDC59_RS03705 eece5d933d4dd50505c232ebcc794133 188 Pfam PF04264 YceI-like domain 28 184 5.0E-32 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CDC59_RS03705 eece5d933d4dd50505c232ebcc794133 188 SMART SM00867 26 186 8.3E-45 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CDC59_RS03705 eece5d933d4dd50505c232ebcc794133 188 SUPERFAMILY SSF101874 28 187 2.22E-40 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CDC59_RS03705 eece5d933d4dd50505c232ebcc794133 188 Gene3D G3DSA:2.40.128.110 28 188 2.9E-39 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CDC59_RS13955 fc237a8d5525418d3b26b4a34ad18bb9 217 Pfam PF02036 SCP-2 sterol transfer family 22 115 1.1E-8 T 29-03-2018 IPR003033 SCP2 sterol-binding domain CDC59_RS11605 0b6bf3fc86d67933af197f058ff1e46e 166 Pfam PF03061 Thioesterase superfamily 65 146 6.4E-12 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CDC59_RS11605 0b6bf3fc86d67933af197f058ff1e46e 166 Gene3D G3DSA:3.10.129.10 4 160 6.2E-21 T 29-03-2018 CDC59_RS11605 0b6bf3fc86d67933af197f058ff1e46e 166 SUPERFAMILY SSF54637 20 156 8.14E-23 T 29-03-2018 IPR029069 HotDog domain CDC59_RS07285 5f94a35ca20d40e27a159e7d92a4ed0e 179 Pfam PF02620 Uncharacterized ACR, COG1399 71 176 7.1E-21 T 29-03-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD CDC59_RS19435 fa6c443f85e983dfd6b164688ffb5926 379 TIGRFAM TIGR03073 release_rtcB: release factor H-coupled RctB family protein 12 367 3.8E-188 T 29-03-2018 IPR017510 Release factor H-coupled RctB family protein CDC59_RS19435 fa6c443f85e983dfd6b164688ffb5926 379 Pfam PF01139 tRNA-splicing ligase RtcB 126 372 7.4E-59 T 29-03-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 CDC59_RS19435 fa6c443f85e983dfd6b164688ffb5926 379 Pfam PF01139 tRNA-splicing ligase RtcB 29 100 2.5E-11 T 29-03-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 CDC59_RS19435 fa6c443f85e983dfd6b164688ffb5926 379 SUPERFAMILY SSF103365 9 372 3.53E-105 T 29-03-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 CDC59_RS05845 cf34a4b76122919aa10eb64c0043f626 151 Pfam PF06903 VirK protein 33 129 3.0E-35 T 29-03-2018 IPR010694 Uncharacterised protein family VirK CDC59_RS06400 7d246756cf1143828a28c1168d4de284 339 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 44 297 2.1E-33 T 29-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CDC59_RS00370 b23e2023c45e9d7f5e2e8b565fcecadf 64 Pfam PF01062 Bestrophin, RFP-TM, chloride channel 7 39 2.1E-7 T 29-03-2018 IPR021134 Bestrophin/UPF0187 Reactome: R-HSA-2672351 CDC59_RS10230 b1d36b4e27b330a6f3d94e5bc778114f 542 Pfam PF08811 Protein of unknown function (DUF1800) 57 439 3.9E-116 T 29-03-2018 IPR014917 Protein of unknown function DUF1800 CDC59_RS10420 6b778fe340059f12f11b777dd1e718b2 104 Pfam PF05154 TM2 domain 14 82 4.5E-17 T 29-03-2018 IPR007829 TM2 domain CDC59_RS21275 680ffbeaa7a45d58c2776d671a665f08 1728 Pfam PF11725 Pathogenicity factor 265 523 1.0E-4 T 29-03-2018 IPR021085 Pathogenicity factor CDC59_RS21275 680ffbeaa7a45d58c2776d671a665f08 1728 Gene3D G3DSA:2.140.10.30 169 716 6.5E-8 T 29-03-2018 CDC59_RS00255 a1e2dcba4d2e9b3a792386567941e636 153 Gene3D G3DSA:3.30.50.10 1 59 0.0011 T 29-03-2018 IPR013088 Zinc finger, NHR/GATA-type GO:0006355|GO:0008270 CDC59_RS03700 9a4d0465a27432f0e3b6e3ea842c1827 194 Pfam PF01292 Prokaryotic cytochrome b561 21 191 8.8E-31 T 29-03-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 CDC59_RS03700 9a4d0465a27432f0e3b6e3ea842c1827 194 Gene3D G3DSA:1.20.950.20 19 193 9.7E-34 T 29-03-2018 CDC59_RS03700 9a4d0465a27432f0e3b6e3ea842c1827 194 SUPERFAMILY SSF81342 21 191 4.16E-38 T 29-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 CDC59_RS01765 6e31190026f6b119eb090e399c7cb541 163 Pfam PF14317 YcxB-like protein 91 148 3.7E-6 T 29-03-2018 IPR025588 YcxB-like protein CDC59_RS01455 d0d1855587c52bbc5a26aabc70a235c2 392 SUPERFAMILY SSF101898 46 250 7.85E-23 T 29-03-2018 CDC59_RS01455 d0d1855587c52bbc5a26aabc70a235c2 392 Gene3D G3DSA:2.120.10.30 286 389 0.037 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CDC59_RS01455 d0d1855587c52bbc5a26aabc70a235c2 392 Gene3D G3DSA:2.120.10.30 26 174 5.4E-10 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CDC59_RS01455 d0d1855587c52bbc5a26aabc70a235c2 392 Gene3D G3DSA:2.120.10.30 175 262 6.3E-5 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CDC59_RS11665 bd0c8f594acfb60a5fbe23a9614d86c8 205 PIRSF PIRSF016919 8 204 1.9E-51 T 29-03-2018 IPR007038 Hydrogenase/Urease accessory protein HupE/UreJ protein CDC59_RS11665 bd0c8f594acfb60a5fbe23a9614d86c8 205 Pfam PF04955 HupE / UreJ protein 16 200 8.1E-58 T 29-03-2018 IPR007038 Hydrogenase/Urease accessory protein HupE/UreJ protein CDC59_RS03625 7edb0ffb59b005c94fd8b95167cb61c8 345 Gene3D G3DSA:3.40.50.2300 12 216 2.2E-17 T 29-03-2018 CDC59_RS03625 7edb0ffb59b005c94fd8b95167cb61c8 345 Pfam PF00072 Response regulator receiver domain 97 158 5.0E-8 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CDC59_RS03625 7edb0ffb59b005c94fd8b95167cb61c8 345 SUPERFAMILY SSF52172 17 54 7.12E-13 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS03625 7edb0ffb59b005c94fd8b95167cb61c8 345 SUPERFAMILY SSF52172 100 174 7.12E-13 T 29-03-2018 IPR011006 CheY-like superfamily CDC59_RS05515 5ef127625c69086e827348aec5f5b876 315 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 54 77 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CDC59_RS05515 5ef127625c69086e827348aec5f5b876 315 TIGRFAM TIGR02198 rfaE_dom_I: bifunctional protein RfaE, domain I 9 313 3.3E-129 T 29-03-2018 IPR011913 RfaE bifunctional protein, domain I GO:0005975|GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167 CDC59_RS05515 5ef127625c69086e827348aec5f5b876 315 Gene3D G3DSA:3.40.1190.20 3 312 3.5E-61 T 29-03-2018 IPR029056 Ribokinase-like CDC59_RS05515 5ef127625c69086e827348aec5f5b876 315 Pfam PF00294 pfkB family carbohydrate kinase 15 303 1.0E-42 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB CDC59_RS05515 5ef127625c69086e827348aec5f5b876 315 SUPERFAMILY SSF53613 15 312 1.04E-57 T 29-03-2018 IPR029056 Ribokinase-like CDC59_RS08930 a6ee15ffe7725e0cb55c2f2dc9bdcf83 144 Pfam PF00582 Universal stress protein family 1 144 8.2E-29 T 29-03-2018 IPR006016 UspA GO:0006950 CDC59_RS08930 a6ee15ffe7725e0cb55c2f2dc9bdcf83 144 Gene3D G3DSA:3.40.50.620 1 144 4.2E-31 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDC59_RS08930 a6ee15ffe7725e0cb55c2f2dc9bdcf83 144 SUPERFAMILY SSF52402 1 144 4.44E-34 T 29-03-2018 CDC59_RS08930 a6ee15ffe7725e0cb55c2f2dc9bdcf83 144 PRINTS PR01438 Universal stress protein signature 2 20 2.3E-16 T 29-03-2018 IPR006015 Universal stress protein A CDC59_RS08930 a6ee15ffe7725e0cb55c2f2dc9bdcf83 144 PRINTS PR01438 Universal stress protein signature 122 144 2.3E-16 T 29-03-2018 IPR006015 Universal stress protein A CDC59_RS08930 a6ee15ffe7725e0cb55c2f2dc9bdcf83 144 PRINTS PR01438 Universal stress protein signature 104 116 2.3E-16 T 29-03-2018 IPR006015 Universal stress protein A CDC59_RS19335 52db33c85d18cd2c4e8904c424684761 121 Pfam PF16068 Domain of unknown function (DUF4810) 30 112 1.5E-32 T 29-03-2018 IPR014508 Uncharacterised conserved protein withTPR-like repeats CDC59_RS19335 52db33c85d18cd2c4e8904c424684761 121 PIRSF PIRSF020555 1 121 2.5E-60 T 29-03-2018 IPR014508 Uncharacterised conserved protein withTPR-like repeats CDC59_RS05325 6ab916a3136fa6766287a46b3633f7a8 120 Pfam PF10618 Phage tail tube protein 23 110 1.1E-12 T 29-03-2018 IPR019596 Bacteriophage Mu, GpM, tail tube CDC59_RS10375 f922a982398f2824eb01a97a41dd8656 167 Gene3D G3DSA:1.10.287.540 32 78 0.0021 T 29-03-2018 CDC59_RS11895 b1664a21fcd633f7a64240baf73108b6 146 Pfam PF12279 Protein of unknown function (DUF3619) 8 144 5.7E-46 T 29-03-2018 IPR022064 Protein of unknown function DUF3619 CDC59_RS11325 6f5cf216fa757d8468b5a73d7623828a 243 Pfam PF01618 MotA/TolQ/ExbB proton channel family 98 206 3.9E-34 T 29-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 CDC59_RS08695 8a23835b9d4d85cf486c39131153e70f 336 Pfam PF01384 Phosphate transporter family 25 325 1.0E-91 T 29-03-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 CDC59_RS06320 37313255d7e1e19744c13d208c7ff1e9 98 Pfam PF06803 Protein of unknown function (DUF1232) 36 68 6.5E-12 T 29-03-2018 IPR010652 Protein of unknown function DUF1232 CDC59_RS13215 7cf71db5baf493a8a070d5e760ca5497 210 Gene3D G3DSA:2.40.50.140 17 133 5.7E-7 T 29-03-2018 CDC59_RS23755 d82174f2bc72b708dca4d31386db07f9 135 Gene3D G3DSA:2.40.128.20 42 133 1.6E-12 T 29-03-2018 IPR012674 Calycin CDC59_RS00960 5d816dcd7e641fa4133872475087b67c 691 Pfam PF12902 Ferritin-like 33 302 9.8E-25 T 29-03-2018 CDC59_RS03595 1138a3a286d7831720c3eb53594b7050 140 Pfam PF03653 Uncharacterised protein family (UPF0093) 2 140 1.2E-42 T 29-03-2018 IPR005265 Uncharacterised protein family UPF0093 CDC59_RS03595 1138a3a286d7831720c3eb53594b7050 140 PIRSF PIRSF004638 1 140 5.5E-47 T 29-03-2018 IPR005265 Uncharacterised protein family UPF0093 CDC59_RS07730 82cba8b74da1136bfda13376ecd10f2c 180 Pfam PF13761 Domain of unknown function (DUF4166) 17 172 6.1E-38 T 29-03-2018 IPR025311 Domain of unknown function DUF4166 CDC59_RS04300 b639fc01bd7eb92f634e2de0973a938b 441 Pfam PF09594 Glycosyltransferase family 87 111 339 9.1E-34 T 29-03-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 CDC59_RS09975 e7617ea3d5d120d20dfff03c31bed7da 239 SMART SM00382 32 216 1.6E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain CDC59_RS09975 e7617ea3d5d120d20dfff03c31bed7da 239 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CDC59_RS09975 e7617ea3d5d120d20dfff03c31bed7da 239 Gene3D G3DSA:3.40.50.300 1 239 3.6E-55 T 29-03-2018 CDC59_RS09975 e7617ea3d5d120d20dfff03c31bed7da 239 SUPERFAMILY SSF52540 6 233 5.88E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CDC59_RS09975 e7617ea3d5d120d20dfff03c31bed7da 239 Pfam PF00005 ABC transporter 23 167 4.2E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CDC59_RS16940 ca3f8a26ac890e90146d92012a7d99ed 209 Gene3D G3DSA:3.90.550.10 1 198 3.3E-25 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDC59_RS16940 ca3f8a26ac890e90146d92012a7d99ed 209 Pfam PF12804 MobA-like NTP transferase domain 8 172 3.5E-31 T 29-03-2018 IPR025877 MobA-like NTP transferase CDC59_RS16940 ca3f8a26ac890e90146d92012a7d99ed 209 SUPERFAMILY SSF53448 6 196 5.63E-21 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CDC59_RS12650 dc4d475d5013516f75710237ce27c7ce 190 Gene3D G3DSA:3.40.50.620 37 158 9.9E-22 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CDC59_RS12650 dc4d475d5013516f75710237ce27c7ce 190 Pfam PF02698 DUF218 domain 47 181 1.7E-21 T 29-03-2018 IPR003848 Domain of unknown function DUF218 CDC59_RS17645 5e973517c6262f36350d43edae261e08 259 SUPERFAMILY SSF161098 22 219 1.96E-31 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS17645 5e973517c6262f36350d43edae261e08 259 Gene3D G3DSA:1.10.3720.10 17 233 4.8E-27 T 29-03-2018 CDC59_RS17645 5e973517c6262f36350d43edae261e08 259 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 69 216 1.2E-8 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CDC59_RS13780 31079c2d356554c8bd6e5b145475de42 134 Pfam PF04519 Polymer-forming cytoskeletal 13 113 1.8E-26 T 29-03-2018 IPR007607 Protein of unknown function DUF583 CDC59_RS13780 31079c2d356554c8bd6e5b145475de42 134 Gene3D G3DSA:2.160.10.10 38 132 0.0018 T 29-03-2018 CDC59_RS17375 f2b30128f724442fe430097157009436 186 Pfam PF03729 Short repeat of unknown function (DUF308) 72 141 2.6E-9 T 29-03-2018 IPR005325 Protein of unknown function DUF308, membrane CDC59_RS17375 f2b30128f724442fe430097157009436 186 Pfam PF03729 Short repeat of unknown function (DUF308) 14 85 1.8E-9 T 29-03-2018 IPR005325 Protein of unknown function DUF308, membrane CDC59_RS17375 f2b30128f724442fe430097157009436 186 Pfam PF03729 Short repeat of unknown function (DUF308) 129 181 7.6E-4 T 29-03-2018 IPR005325 Protein of unknown function DUF308, membrane CDC59_RS16145 01c471c8047240c3ecff10bd5e7073a5 95 Pfam PF10006 Uncharacterized conserved protein (DUF2249) 10 78 1.3E-28 T 29-03-2018 IPR018720 Domain of unknown function DUF2249 CDC59_RS04310 80c1ef56a2fe88cff80b43868cdeddb2 151 Pfam PF07811 TadE-like protein 21 63 4.2E-16 T 29-03-2018 IPR012495 TadE-like CDC59_RS06860 9ff46854f6eb5d99dd4280bba39e3f0d 76 Pfam PF04606 Ogr/Delta-like zinc finger 4 49 9.7E-12 T 29-03-2018 IPR007684 Zinc finger, Ogr/Delta-type CDC59_RS12255 db9ddcb97555a4aa6177f64cb0d88a5a 173 Pfam PF11749 Protein of unknown function (DUF3305) 17 160 3.7E-52 T 29-03-2018 IPR021736 Protein of unknown function DUF3305 CDC59_RS04670 c0d700e238f0537f08995d34cd427efe 312 Pfam PF16074 Type IV Pilus-assembly protein W 168 303 1.2E-19 T 29-03-2018 IPR032092 Type IV Pilus-assembly protein W GO:0043683 CDC59_RS16165 57b7df56be8e2575d02d46ef3a263c9a 272 Gene3D G3DSA:3.40.710.10 20 265 1.4E-25 T 29-03-2018 CDC59_RS16165 57b7df56be8e2575d02d46ef3a263c9a 272 SUPERFAMILY SSF56601 20 259 1.3E-33 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CDC59_RS16165 57b7df56be8e2575d02d46ef3a263c9a 272 Pfam PF00905 Penicillin binding protein transpeptidase domain 43 256 5.7E-41 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CDC59_RS23945 38ee65fbd6d25461fb89b87cd20bbab6 264 SUPERFAMILY SSF88713 22 165 2.78E-9 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CDC59_RS23945 38ee65fbd6d25461fb89b87cd20bbab6 264 Gene3D G3DSA:3.20.20.370 33 239 5.9E-10 T 29-03-2018 CDC59_RS23945 38ee65fbd6d25461fb89b87cd20bbab6 264 Pfam PF10096 Uncharacterized protein conserved in bacteria (DUF2334) 6 153 1.5E-22 T 29-03-2018 IPR018763 Protein of unknown function DUF2334 CDC59_RS14765 60a596ed348b5176c8f379744a22f457 289 SUPERFAMILY SSF47240 5 276 1.27E-49 T 29-03-2018 IPR009078 Ferritin-like superfamily CDC59_RS14765 60a596ed348b5176c8f379744a22f457 289 Gene3D G3DSA:1.10.620.20 3 200 1.2E-29 T 29-03-2018 CDC59_RS22150 b5c0322ca403e4b1192340133296bb3b 218 SUPERFAMILY SSF142695 28 185 1.24E-49 T 29-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CDC59_RS22150 b5c0322ca403e4b1192340133296bb3b 218 Pfam PF00925 GTP cyclohydrolase II 35 183 9.5E-53 T 29-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CDC59_RS20730 58a816c2843f0f7a4198e1c80effcc37 397 Pfam PF01435 Peptidase family M48 65 134 2.1E-7 T 29-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CDC59_RS20730 58a816c2843f0f7a4198e1c80effcc37 397 Gene3D G3DSA:3.30.2010.10 54 144 3.5E-9 T 29-03-2018 CDC59_RS15480 fa21d686b0002c42804f199cca215357 285 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 4 272 3.4E-33 T 29-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 CDC59_RS15480 fa21d686b0002c42804f199cca215357 285 PIRSF PIRSF026649 1 281 4.2E-69 T 29-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 CDC59_RS04880 21952b04034d935795bd4fb7bf8d6357 68 Pfam PF11278 Protein of unknown function (DUF3079) 1 51 6.4E-34 T 29-03-2018 IPR021430 Protein of unknown function DUF3079 CDC59_RS03305 b61a4d7539b0df00a919e61a831138c0 303 Pfam PF01578 Cytochrome C assembly protein 71 299 2.2E-24 T 29-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 CDC59_RS09800 8e9c64220d12bc5774164878db390e67 96 Pfam PF16290 Domain of unknown function (DUF4936) 6 90 6.0E-30 T 29-03-2018 IPR032556 Protein of unknown function DUF4936 CDC59_RS08540 7d98d3382df4450878e61bc32730ec1d 248 Pfam PF13386 Cytochrome C biogenesis protein transmembrane region 9 227 2.1E-46 T 29-03-2018 CDC59_RS21980 c524f2dbb6e31a736a1560dafb51de71 217 Pfam PF09998 Uncharacterized protein conserved in bacteria (DUF2239) 9 195 1.4E-77 T 29-03-2018 IPR018715 Protein of unknown function DUF2239 CDC59_RS14830 7c142d28d31e4cf9b064274882836901 85 Pfam PF12091 Protein of unknown function (DUF3567) 1 85 1.3E-35 T 29-03-2018 IPR021951 Protein of unknown function DUF3567 CDC59_RS10435 c4dce7077fe8ab88b077a0b40b1e7e02 241 Pfam PF02754 Cysteine-rich domain 132 216 6.4E-14 T 29-03-2018 IPR004017 Cysteine-rich domain CDC59_RS10435 c4dce7077fe8ab88b077a0b40b1e7e02 241 Pfam PF02754 Cysteine-rich domain 3 84 1.2E-15 T 29-03-2018 IPR004017 Cysteine-rich domain CDC59_RS16325 2622da258692bdb02531b6e539728cd0 347 Pfam PF01882 Protein of unknown function DUF58 231 298 2.6E-13 T 29-03-2018 IPR002881 Domain of unknown function DUF58 CDC59_RS18460 97d230272707e1091bf131bc359f5604 698 Gene3D G3DSA:1.20.120.290 381 460 9.4E-21 T 29-03-2018 CDC59_RS18460 97d230272707e1091bf131bc359f5604 698 Gene3D G3DSA:1.20.120.290 309 380 7.7E-13 T 29-03-2018 CDC59_RS18460 97d230272707e1091bf131bc359f5604 698 Gene3D G3DSA:1.20.120.290 461 562 2.0E-5 T 29-03-2018 CDC59_RS18460 97d230272707e1091bf131bc359f5604 698 Pfam PF05650 Domain of unknown function (DUF802) 376 427 8.1E-14 T 29-03-2018 IPR008520 Domain of unknown function DUF802 CDC59_RS18460 97d230272707e1091bf131bc359f5604 698 Pfam PF05650 Domain of unknown function (DUF802) 321 373 8.0E-16 T 29-03-2018 IPR008520 Domain of unknown function DUF802 CDC59_RS09255 23715c792e15276ba15b6b72551e9171 142 Pfam PF01957 NfeD-like C-terminal, partner-binding 7 142 4.8E-9 T 29-03-2018 IPR002810 NfeD-like, C-terminal domain CDC59_RS09255 23715c792e15276ba15b6b72551e9171 142 Gene3D G3DSA:2.40.50.140 72 142 1.6E-7 T 29-03-2018 CDC59_RS03440 2446ca07daf24381d6f3a8df0c1c15b6 224 Gene3D G3DSA:3.30.460.10 72 207 8.4E-5 T 29-03-2018 CDC59_RS08390 3acff64db0241f95a16147e2fee2e575 286 Pfam PF07264 Etoposide-induced protein 2.4 (EI24) 8 218 2.0E-22 T 29-03-2018 CDC59_RS16280 4346e50deba9ee855d8716f213ce7b44 119 Gene3D G3DSA:3.30.450.30 1 118 1.9E-21 T 29-03-2018 CDC59_RS22955 a5872e8ff832e4e3d047874ece8a721a 309 Gene3D G3DSA:1.20.1250.20 71 304 2.4E-7 T 29-03-2018 CDC59_RS13785 f6524dc31376c6ab1dbcbbe34eb165c3 251 Gene3D G3DSA:1.20.5.340 58 123 1.9E-4 T 29-03-2018 CDC59_RS18135 01c0f37a8f9727cd1a3234d86dce8a9d 220 SUPERFAMILY SSF49354 4 122 3.92E-22 T 29-03-2018 IPR008962 PapD-like CDC59_RS18135 01c0f37a8f9727cd1a3234d86dce8a9d 220 Gene3D G3DSA:2.60.40.10 6 125 2.9E-26 T 29-03-2018 IPR013783 Immunoglobulin-like fold CDC59_RS18135 01c0f37a8f9727cd1a3234d86dce8a9d 220 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 7 123 2.2E-20 T 29-03-2018 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 CDC59_RS16455 f661a2fbe6e21e2bfb030bec62f29dd0 756 Pfam PF05593 RHS Repeat 177 214 1.4E-4 T 29-03-2018 IPR031325 RHS repeat CDC59_RS16455 f661a2fbe6e21e2bfb030bec62f29dd0 756 Pfam PF05593 RHS Repeat 125 160 1.3E-9 T 29-03-2018 IPR031325 RHS repeat CDC59_RS16455 f661a2fbe6e21e2bfb030bec62f29dd0 756 Pfam PF05593 RHS Repeat 229 265 1.4E-4 T 29-03-2018 IPR031325 RHS repeat CDC59_RS16455 f661a2fbe6e21e2bfb030bec62f29dd0 756 Pfam PF05593 RHS Repeat 35 66 6.8E-12 T 29-03-2018 IPR031325 RHS repeat CDC59_RS16455 f661a2fbe6e21e2bfb030bec62f29dd0 756 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 558 622 1.1E-19 T 29-03-2018 IPR022385 Rhs repeat-associated core GO:0097264 CDC59_RS16455 f661a2fbe6e21e2bfb030bec62f29dd0 756 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 176 205 0.0026 T 29-03-2018 IPR006530 YD repeat CDC59_RS16455 f661a2fbe6e21e2bfb030bec62f29dd0 756 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 111 144 0.0024 T 29-03-2018 IPR006530 YD repeat CDC59_RS16455 f661a2fbe6e21e2bfb030bec62f29dd0 756 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 35 63 1.4E-7 T 29-03-2018 IPR006530 YD repeat CDC59_RS00740 cb07220287a70cc01e225c7aa9e65993 252 Pfam PF01925 Sulfite exporter TauE/SafE 6 244 7.4E-41 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CDC59_RS04220 bff1031cc3e3e78639e923f0a8daead7 558 Pfam PF02470 MlaD protein 312 415 5.4E-15 T 29-03-2018 IPR003399 Mce/MlaD CDC59_RS04220 bff1031cc3e3e78639e923f0a8daead7 558 Pfam PF02470 MlaD protein 67 154 4.0E-10 T 29-03-2018 IPR003399 Mce/MlaD CDC59_RS04220 bff1031cc3e3e78639e923f0a8daead7 558 Pfam PF02470 MlaD protein 184 241 8.3E-7 T 29-03-2018 IPR003399 Mce/MlaD CDC59_RS04220 bff1031cc3e3e78639e923f0a8daead7 558 Gene3D G3DSA:1.10.287.620 383 544 2.4E-5 T 29-03-2018 CDC59_RS03815 5433510cf62c224ac8e9069e012b0110 314 Pfam PF00892 EamA-like transporter family 162 286 2.9E-8 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CDC59_RS03815 5433510cf62c224ac8e9069e012b0110 314 SUPERFAMILY SSF103481 193 291 4.71E-7 T 29-03-2018 CDC59_RS18515 5a964f9dfa97d5eab6e380a970b19387 199 SMART SM00696 3 69 4.5E-5 T 29-03-2018 IPR006616 DM9 repeat CDC59_RS18515 5a964f9dfa97d5eab6e380a970b19387 199 Pfam PF11901 Protein of unknown function (DUF3421) 7 59 6.3E-8 T 29-03-2018 IPR024518 Domain of unknown function DUF3421 CDC59_RS16990 6923981bd3b4d86b546dac5dfb3771e9 153 SUPERFAMILY SSF140566 4 125 1.83E-20 T 29-03-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 CDC59_RS16990 6923981bd3b4d86b546dac5dfb3771e9 153 Gene3D G3DSA:1.20.58.300 3 125 5.2E-18 T 29-03-2018 CDC59_RS16990 6923981bd3b4d86b546dac5dfb3771e9 153 Pfam PF05130 FlgN protein 2 141 1.5E-27 T 29-03-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 CDC59_RS00035 c8aaff198b546cbc646323fc37f53544 171 Pfam PF04191 Phospholipid methyltransferase 47 147 4.3E-19 T 29-03-2018 IPR007318 Phospholipid methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-1483191 CDC59_RS17355 68fe9b9a0d05f35b9891cc06ff514e16 593 Pfam PF04183 IucA / IucC family 146 388 6.4E-64 T 29-03-2018 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0015343|GO:0019290 CDC59_RS17355 68fe9b9a0d05f35b9891cc06ff514e16 593 Pfam PF06276 Ferric iron reductase FhuF-like transporter 408 578 9.4E-35 T 29-03-2018 IPR022770 Ferric iron reductase FhuF domain CDC59_RS11365 c30660f5dd9653c690c89a267f6a602a 66 Pfam PF05433 Glycine zipper 2TM domain 29 64 2.9E-6 T 29-03-2018 IPR008816 Glycine zipper 2TM domain GO:0019867 CDC59_RS06215 24dc9fc5f21fa375f171b9443946e387 435 Pfam PF04932 O-Antigen ligase 197 352 8.5E-20 T 29-03-2018 IPR007016 O-antigen ligase-related CDC59_RS12250 4856d37ce4d28eee23e39f9172d060ad 197 Pfam PF11748 Protein of unknown function (DUF3306) 5 122 2.9E-38 T 29-03-2018 IPR021735 Protein of unknown function DUF3306 CDC59_RS19405 236d8a656b19eaf8424f1be38d53a0cb 165 Pfam PF09933 Predicted small integral membrane protein (DUF2165) 5 160 1.1E-59 T 29-03-2018 IPR018681 Protein of unknown function DUF2165, transmembrane CDC59_RS14440 56269c246fa77378b6e5a126d0427510 69 Pfam PF11137 Protein of unknown function (DUF2909) 1 60 2.4E-24 T 29-03-2018 IPR021313 Protein of unknown function DUF2909 CDC59_RS15215 f276b4610cce2a8162f463128c30ab34 147 Pfam PF14478 Domain of unknown function (DUF4430) 70 115 2.3E-6 T 29-03-2018 IPR027954 Domain of unknown function DUF4430 Reactome: R-HSA-196741 CDC59_RS05300 f7f347b0fb76e6aafd47dc9f86243d3e 300 Pfam PF10124 Mu-like prophage major head subunit gpT 9 300 7.1E-100 T 29-03-2018 IPR018774 Bacteriophage Mu, GpT CDC59_RS22785 30d3b670d931e04cc2b982c5717df1cb 155 Pfam PF11697 Protein of unknown function (DUF3293) 59 136 1.4E-18 T 29-03-2018 IPR021710 Protein of unknown function DUF3293 CDC59_RS18760 207cf5ab959e185c7382e23a370a58c9 568 Pfam PF11394 Protein of unknown function (DUF2875) 104 561 7.3E-196 T 29-03-2018 IPR021531 Protein of unknown function DUF2875 CDC59_RS12405 6d46a1ac37bbdbcc111c3578b9d21d9e 142 Pfam PF10667 Protein of unknown function (DUF2486) 50 136 1.3E-5 T 29-03-2018 IPR018924 Protein of unknown function DUF2486 CDC59_RS11980 86088e4b030771abc4fd91dcf164cb23 283 Gene3D G3DSA:1.20.120.330 14 162 4.4E-5 T 29-03-2018 CDC59_RS19390 0275551035d11b997786b616ed1dbd5e 298 SUPERFAMILY SSF103481 187 284 1.06E-11 T 29-03-2018 CDC59_RS19390 0275551035d11b997786b616ed1dbd5e 298 SUPERFAMILY SSF103481 40 144 7.19E-15 T 29-03-2018 CDC59_RS19390 0275551035d11b997786b616ed1dbd5e 298 Pfam PF00892 EamA-like transporter family 6 139 9.4E-20 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CDC59_RS19390 0275551035d11b997786b616ed1dbd5e 298 Pfam PF00892 EamA-like transporter family 150 282 5.6E-17 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CDC59_RS10865 6a5a229ec865408b15f8cea85f80f2e7 365 Pfam PF01757 Acyltransferase family 26 330 6.8E-26 T 29-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CDC59_RS19870 104ab648ddad47115f559e7292b23424 177 Pfam PF06127 Protein of unknown function (DUF962) 1 148 1.6E-22 T 29-03-2018 IPR009305 Protein of unknown function DUF962 CDC59_RS17200 be060bd47dea4848f7b5fcad558a6c96 517 PRINTS PR01007 Flagellar hook-length control protein signature 395 413 1.8E-7 T 29-03-2018 IPR001635 Flagellar hook-length control protein FliK GO:0009424|GO:0044780 CDC59_RS17200 be060bd47dea4848f7b5fcad558a6c96 517 PRINTS PR01007 Flagellar hook-length control protein signature 428 451 1.8E-7 T 29-03-2018 IPR001635 Flagellar hook-length control protein FliK GO:0009424|GO:0044780 CDC59_RS17200 be060bd47dea4848f7b5fcad558a6c96 517 PRINTS PR01007 Flagellar hook-length control protein signature 370 392 1.8E-7 T 29-03-2018 IPR001635 Flagellar hook-length control protein FliK GO:0009424|GO:0044780 CDC59_RS17200 be060bd47dea4848f7b5fcad558a6c96 517 PRINTS PR01007 Flagellar hook-length control protein signature 128 145 1.8E-7 T 29-03-2018 IPR001635 Flagellar hook-length control protein FliK GO:0009424|GO:0044780 CDC59_RS17200 be060bd47dea4848f7b5fcad558a6c96 517 Pfam PF02120 Flagellar hook-length control protein FliK 381 462 2.6E-19 T 29-03-2018 IPR021136 Flagellar hook-length control protein-like, C-terminal CDC59_RS18200 9bf57cd814527a12932b21988be7e457 246 PIRSF PIRSF032817 1 246 4.0E-91 T 29-03-2018 IPR017008 Uncharacterised conserved protein UCP032817 CDC59_RS22645 0154acc7fabd42c8273dc761694ebcf0 487 Pfam PF05552 Conserved TM helix 96 144 1.3E-11 T 29-03-2018 IPR008910 Conserved TM helix CDC59_RS22645 0154acc7fabd42c8273dc761694ebcf0 487 Pfam PF05552 Conserved TM helix 279 325 1.2E-13 T 29-03-2018 IPR008910 Conserved TM helix CDC59_RS22645 0154acc7fabd42c8273dc761694ebcf0 487 Pfam PF05552 Conserved TM helix 187 234 3.2E-14 T 29-03-2018 IPR008910 Conserved TM helix CDC59_RS22645 0154acc7fabd42c8273dc761694ebcf0 487 Pfam PF05552 Conserved TM helix 6 53 7.5E-13 T 29-03-2018 IPR008910 Conserved TM helix CDC59_RS12745 14557b6faf6219334a4063f35a76f69b 321 SUPERFAMILY SSF56281 44 320 5.24E-46 T 29-03-2018 IPR001279 Metallo-beta-lactamase CDC59_RS12745 14557b6faf6219334a4063f35a76f69b 321 Pfam PF12706 Beta-lactamase superfamily domain 75 287 1.5E-13 T 29-03-2018 IPR001279 Metallo-beta-lactamase CDC59_RS12745 14557b6faf6219334a4063f35a76f69b 321 Gene3D G3DSA:3.60.15.10 43 321 6.7E-41 T 29-03-2018 IPR001279 Metallo-beta-lactamase CDC59_RS23815 0b5b9578d23e12d73d76471f86bf3957 540 Pfam PF03929 PepSY-associated TM region 11 377 2.0E-56 T 29-03-2018 IPR005625 PepSY-associated TM protein CDC59_RS23120 41d72ae298aabe465d2bb9e8507ca9dc 286 TIGRFAM TIGR03818 MotA1: flagellar motor stator protein MotA 2 281 1.0E-123 T 29-03-2018 IPR022522 Flagellar motor stator, MotA CDC59_RS23120 41d72ae298aabe465d2bb9e8507ca9dc 286 Pfam PF01618 MotA/TolQ/ExbB proton channel family 139 237 1.3E-11 T 29-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 CDC59_RS23120 41d72ae298aabe465d2bb9e8507ca9dc 286 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 205 222 - T 29-03-2018 IPR000540 Flagellar motor protein MotA, conserved site CDC59_RS14740 e86dfafde9d91af6d765ff9bcf16075a 374 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 132 370 2.3E-64 T 29-03-2018 IPR003453 ABC transport permease subunit MlaE, Proteobacteria CDC59_RS14740 e86dfafde9d91af6d765ff9bcf16075a 374 Pfam PF02405 Permease MlaE 159 367 5.7E-66 T 29-03-2018 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 CDC59_RS05820 2bbacfbf43313949f659e34e01aac3a1 159 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 78 146 2.9E-8 T 29-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal CDC59_RS12685 c2aaeb88fa309a53dd009cb5d6dc0514 206 Pfam PF13548 Domain of unknown function (DUF4126) 6 176 4.3E-56 T 29-03-2018 IPR025196 Domain of unknown function DUF4126 CDC59_RS21950 fef60771f8e7567ff147cd96f63717ee 46 Pfam PF08085 Entericidin EcnA/B family 19 39 5.5E-10 T 29-03-2018 IPR012556 Entericidin A/B GO:0009636|GO:0016020 CDC59_RS02785 ee5be8a00b7f308e169c658bbf673d15 106 Pfam PF12778 PXPV repeat (3 copies) 32 53 3.2E-4 T 29-03-2018 IPR024446 PXPV repeat CDC59_RS02785 ee5be8a00b7f308e169c658bbf673d15 106 Pfam PF12778 PXPV repeat (3 copies) 47 65 0.0089 T 29-03-2018 IPR024446 PXPV repeat CDC59_RS03620 41ba2e369e10106777ec93348ed27fa2 467 SUPERFAMILY SSF53335 266 429 3.22E-16 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CDC59_RS03620 41ba2e369e10106777ec93348ed27fa2 467 Gene3D G3DSA:3.40.50.150 231 466 1.8E-13 T 29-03-2018 CDC59_RS03620 41ba2e369e10106777ec93348ed27fa2 467 Pfam PF13649 Methyltransferase domain 289 402 1.3E-9 T 29-03-2018 CDC59_RS18300 44ff2c450355a256a5dc8e507b66fe8f 136 PIRSF PIRSF037181 1 132 5.3E-50 T 29-03-2018 IPR014958 DGC CDC59_RS18300 44ff2c450355a256a5dc8e507b66fe8f 136 Pfam PF08859 DGC domain 8 107 1.4E-31 T 29-03-2018 IPR014958 DGC CDC59_RS19750 23b37211015d4a99b02f6fcb963b12e3 89 Pfam PF05488 PAAR motif 9 80 3.3E-25 T 29-03-2018 IPR008727 PAAR motif CDC59_RS01490 0ab809a755856e2bc66e6798a42fb2d8 484 SUPERFAMILY SSF51905 3 201 4.66E-20 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS01490 0ab809a755856e2bc66e6798a42fb2d8 484 SUPERFAMILY SSF51905 313 354 4.66E-20 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS01490 0ab809a755856e2bc66e6798a42fb2d8 484 Gene3D G3DSA:3.50.50.60 2 354 1.7E-21 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CDC59_RS15250 43f624978f0b44f349a2f7d99610018e 100 Pfam PF13223 Protein of unknown function (DUF4031) 3 78 1.9E-28 T 29-03-2018 IPR025109 Domain of unknown function DUF4031 CDC59_RS04560 90543acbd322e338aeb8250b29132d0f 200 Pfam PF07273 Protein of unknown function (DUF1439) 49 187 8.3E-17 T 29-03-2018 IPR010835 Protein of unknown function DUF1439 CDC59_RS11900 d3aa873453159123db2f81bbd20ce01b 282 Pfam PF11304 Protein of unknown function (DUF3106) 76 175 2.6E-32 T 29-03-2018 IPR021455 Protein of unknown function DUF3106 CDC59_RS19490 97f0e2186d810d0059fa8b6e590c6292 270 Pfam PF09948 Predicted metal-binding integral membrane protein (DUF2182) 70 257 1.8E-59 T 29-03-2018 IPR018688 Protein of unknown function DUF2182, transmembrane, metal-binding CDC59_RS01535 3a79d01db7ea2a51e7954175f1fc9e8d 146 Gene3D G3DSA:1.20.950.20 51 146 4.4E-5 T 29-03-2018 CDC59_RS05895 75169d388e2016c9f3ab8a40d11ac87a 186 Gene3D G3DSA:3.40.50.10070 41 185 5.6E-12 T 29-03-2018 CDC59_RS04930 25bd2ef9df6cb9ba743bcc3bad01b800 749 Pfam PF05170 AsmA family 6 594 9.9E-105 T 29-03-2018 IPR007844 AsmA CDC59_RS20205 2f62e48aaacadc3124229cace5b66df6 161 Gene3D G3DSA:1.25.40.10 7 158 1.7E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CDC59_RS20205 2f62e48aaacadc3124229cace5b66df6 161 TIGRFAM TIGR02561 HrpB1_HrpK: type III secretion protein HrpB1/HrpK 2 158 3.1E-57 T 29-03-2018 IPR013394 Type III secretion system, HrpB1/HrpK CDC59_RS20205 2f62e48aaacadc3124229cace5b66df6 161 Pfam PF09613 Bacterial type III secretion protein (HrpB1_HrpK) 1 128 7.7E-47 T 29-03-2018 IPR013394 Type III secretion system, HrpB1/HrpK CDC59_RS13305 bbd82e42b7c14128fbc8885f8ea4a4b3 288 Pfam PF05655 Pseudomonas avirulence D protein (AvrD) 5 127 3.2E-17 T 29-03-2018 IPR008799 Pseudomonas avirulence D CDC59_RS13305 bbd82e42b7c14128fbc8885f8ea4a4b3 288 Pfam PF05655 Pseudomonas avirulence D protein (AvrD) 189 288 2.3E-22 T 29-03-2018 IPR008799 Pseudomonas avirulence D CDC59_RS15960 8aeb885a4c65dd0dadf8808eda2a3744 356 Pfam PF04796 Plasmid encoded RepA protein 121 299 1.7E-35 T 29-03-2018 IPR006881 Plasmid encoded RepA protein CDC59_RS00140 04cab5bab7a3da1bb6d90929220f5cc9 64 Pfam PF04328 Selenoprotein, putative 5 64 4.1E-30 T 29-03-2018 IPR007423 Selenoprotein, putative CDC59_RS19880 7a6df6d2528a97a67b2e1575ebf29fea 578 Pfam PF10460 Peptidase M30 219 578 1.6E-177 T 29-03-2018 IPR019501 Peptidase M30, hyicolysin CDC59_RS01705 0aa60fc5f21cd3df422347aec8850afc 283 Pfam PF01203 Type II secretion system (T2SS), protein N 64 280 1.6E-41 T 29-03-2018 IPR022792 Type II secretion system, protein N CDC59_RS07625 394adddd01a115502dd86334b340fd8f 359 PIRSF PIRSF015283 1 353 3.5E-126 T 29-03-2018 IPR016631 Regulatory, RpfE CDC59_RS03290 3596e90f258c7275beb0305184ace13f 197 Pfam PF01914 MarC family integral membrane protein 5 192 4.7E-50 T 29-03-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 CDC59_RS03290 3596e90f258c7275beb0305184ace13f 197 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 8 190 6.1E-31 T 29-03-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 CDC59_RS06480 85dca92326a75cbc350973b631eb6cc7 143 Pfam PF12779 YXWGXW repeat (2 copies) 80 104 20.0 T 29-03-2018 IPR024447 YXWGXW repeat CDC59_RS06480 85dca92326a75cbc350973b631eb6cc7 143 Pfam PF12779 YXWGXW repeat (2 copies) 53 75 1.9E-5 T 29-03-2018 IPR024447 YXWGXW repeat CDC59_RS04590 e05263a5fc01ece3ce15a74383e386b0 190 Pfam PF14235 Domain of unknown function (DUF4337) 30 186 8.7E-36 T 29-03-2018 IPR025570 Protein of unknown function DUF4337 CDC59_RS23630 6b7199b324541339edcf9f2f935e9f61 475 Pfam PF09994 Uncharacterized alpha/beta hydrolase domain (DUF2235) 54 157 3.7E-5 T 29-03-2018 IPR018712 Domain of unknown function DUF2235 CDC59_RS23630 6b7199b324541339edcf9f2f935e9f61 475 Pfam PF09994 Uncharacterized alpha/beta hydrolase domain (DUF2235) 193 267 3.5E-5 T 29-03-2018 IPR018712 Domain of unknown function DUF2235 CDC59_RS04320 02eac8872f37b7ab8aff9b866bebb907 325 Pfam PF00482 Type II secretion system (T2SS), protein F 158 282 4.3E-19 T 29-03-2018 IPR018076 Type II secretion system F domain CDC59_RS16340 4e7d801e393f54e39681ea68c1d37146 520 Pfam PF00916 Sulfate permease family 13 373 4.4E-52 T 29-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 CDC59_RS07545 4cf4e0aa64677cfada3e58dc7aae7bfe 310 Pfam PF03547 Membrane transport protein 155 298 7.1E-11 T 29-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 CDC59_RS05255 fee01bc635f06b443b9fa969033f81b2 210 Pfam PF11363 Protein of unknown function (DUF3164) 15 208 3.8E-79 T 29-03-2018 IPR021505 Bacteriophage B3, Orf6 CDC59_RS14430 fb8f89dd726b0a1ec64d4b2756795eaf 215 Gene3D G3DSA:3.40.30.10 134 212 0.035 T 29-03-2018 CDC59_RS14430 fb8f89dd726b0a1ec64d4b2756795eaf 215 Gene3D G3DSA:3.40.30.10 64 133 0.11 T 29-03-2018 CDC59_RS14430 fb8f89dd726b0a1ec64d4b2756795eaf 215 SUPERFAMILY SSF52833 74 210 1.41E-16 T 29-03-2018 IPR012336 Thioredoxin-like fold CDC59_RS05900 729efc78e2e60d984d0ed7a4be855ff0 483 Gene3D G3DSA:3.30.450.40 161 344 6.4E-5 T 29-03-2018 IPR029016 GAF domain-like CDC59_RS05900 729efc78e2e60d984d0ed7a4be855ff0 483 Pfam PF16963 PelD GGDEF domain 355 479 7.3E-46 T 29-03-2018 IPR031583 PelD, GGDEF domain CDC59_RS16025 5ab72d170df634c0f6291d24cd9fb643 293 Gene3D G3DSA:1.10.3470.10 1 282 7.4E-50 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CDC59_RS16025 5ab72d170df634c0f6291d24cd9fb643 293 Pfam PF02653 Branched-chain amino acid transport system / permease component 6 277 2.1E-48 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CDC59_RS05550 6d0ca14d87d7e951927e5b1b53e60df7 243 Pfam PF05229 Spore Coat Protein U domain 30 114 3.4E-8 T 29-03-2018 IPR007893 Spore coat protein U CDC59_RS00945 c06f6b7a11c9c630e8602cb59123dd91 407 Pfam PF00999 Sodium/hydrogen exchanger family 23 349 8.4E-25 T 29-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CDC59_RS05175 08157d53d14210c9536c45800e61cd23 517 Pfam PF06074 Protein of unknown function (DUF935) 34 511 8.0E-136 T 29-03-2018 IPR009279 Protein of unknown function DUF935 CDC59_RS06850 fc057cedb0517ffc81e365f4721dd261 88 Pfam PF05930 Prophage CP4-57 regulatory protein (AlpA) 29 79 9.6E-23 T 29-03-2018 IPR010260 DNA-binding transcriptional activator AlpA CDC59_RS19575 3927f4ff735e081d6aa6adff7d2321e0 818 Gene3D G3DSA:1.25.40.120 175 602 6.1E-4 T 29-03-2018 CDC59_RS12925 4ea793813a4f37174a8581eee429b0a3 143 Pfam PF02472 Biopolymer transport protein ExbD/TolR 8 138 1.1E-27 T 29-03-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 CDC59_RS04915 becb2d3df4902fe837222b2dc7a2814d 172 Pfam PF12318 Membrane bound FAD containing D-sorbitol dehydrogenase 16 167 5.5E-36 T 29-03-2018 IPR024651 FAD-containing D-sorbitol dehydrogenase small subunit CDC59_RS05440 6fa9f688ce792ac14dad127e4da144e5 169 Pfam PF05433 Glycine zipper 2TM domain 79 118 3.9E-11 T 29-03-2018 IPR008816 Glycine zipper 2TM domain GO:0019867 CDC59_RS04315 709d827d7fcd8de0e8549ea39d9cfe04 314 Pfam PF00482 Type II secretion system (T2SS), protein F 168 296 3.7E-18 T 29-03-2018 IPR018076 Type II secretion system F domain CDC59_RS12740 299182a0c5cbc4578a1f020e844205fe 150 Pfam PF02643 Uncharacterized ACR, COG1430 46 145 5.4E-33 T 29-03-2018 IPR003795 Protein of unknown function DUF192 CDC59_RS00735 be5c8d4b172cc0052189da9c7a761fe1 147 Gene3D G3DSA:3.40.630.30 12 139 3.9E-5 T 29-03-2018 CDC59_RS01960 b2bbc4d636db84483dd3f3d130edf6e3 261 Pfam PF06629 MltA-interacting protein MipA 34 261 1.3E-44 T 29-03-2018 IPR010583 MltA-interacting MipA CDC59_RS09795 59c4834b8908e77cf22b994f0c7902b2 272 Pfam PF05742 Transport and Golgi organisation 2 1 249 1.7E-68 T 29-03-2018 IPR008551 Transport and Golgi organisation protein 2 CDC59_RS03930 047977ae20092b2a8e849a25a4843745 243 Pfam PF04172 LrgB-like family 26 238 2.5E-80 T 29-03-2018 IPR007300 CidB/LrgB family CDC59_RS13045 5728aaf03a083b2a25a45c8156a271a9 358 Pfam PF05987 Bacterial protein of unknown function (DUF898) 22 351 2.1E-114 T 29-03-2018 IPR010295 Protein of unknown function DUF898 CDC59_RS13490 8c92befe1aa80912fa269a6fc0389a7f 186 Gene3D G3DSA:3.30.530.20 10 186 1.6E-8 T 29-03-2018 IPR023393 START-like domain CDC59_RS10360 d94251d86d5f35e8bf0462830f971c06 67 Pfam PF04325 Protein of unknown function (DUF465) 14 57 6.7E-12 T 29-03-2018 IPR007420 Protein of unknown function DUF465 CDC59_RS08605 cf04c9c555771ff1b9270876cc420d3d 304 Pfam PF04116 Fatty acid hydroxylase superfamily 96 235 1.3E-27 T 29-03-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 CDC59_RS05340 1ce40e6097898a31ff01ba4c4b67699c 714 Pfam PF10145 Phage-related minor tail protein 203 382 1.9E-20 T 29-03-2018 IPR010090 Phage tail tape measure protein CDC59_RS11905 4102b351faf194f3bb728e809a194704 176 Pfam PF06271 RDD family 22 170 4.4E-25 T 29-03-2018 IPR010432 RDD CDC59_RS16670 8e2297a2481810e63b2afeda064f6541 125 Gene3D G3DSA:2.130.10.10 1 118 5.6E-4 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CDC59_RS12425 bb41273b40fbeafa848a1a93a19175ad 401 Pfam PF03739 Predicted permease YjgP/YjgQ family 12 395 6.0E-63 T 29-03-2018 IPR005495 Permease LptG/LptF-related GO:0016021 CDC59_RS11730 810b979f51028bb1ddeecf601e868608 153 Pfam PF06676 Protein of unknown function (DUF1178) 1 145 4.3E-52 T 29-03-2018 IPR009562 Protein of unknown function DUF1178 CDC59_RS11730 810b979f51028bb1ddeecf601e868608 153 PIRSF PIRSF032131 1 150 1.2E-56 T 29-03-2018 IPR009562 Protein of unknown function DUF1178 CDC59_RS18800 47f80018e287600e1bbae27f6d74615f 630 Gene3D G3DSA:1.10.287.110 5 122 9.0E-6 T 29-03-2018 IPR001623 DnaJ domain CDC59_RS22325 57f1d5fdfbaf17cd31e38b842cfe330c 120 Pfam PF06993 Protein of unknown function (DUF1304) 12 116 1.0E-35 T 29-03-2018 IPR009732 Protein of unknown function DUF1304 CDC59_RS04835 bebea6ff3ef865f060078afc8600e7eb 91 Pfam PF05957 Bacterial protein of unknown function (DUF883) 2 91 4.5E-33 T 29-03-2018 IPR010279 Protein of unknown function DUF883, ElaB CDC59_RS22505 38917be524d689d237ebec453a8923df 343 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 14 333 1.9E-82 T 29-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CDC59_RS16405 72dade4f31f359e4c05b47ecd8a0d51a 277 Pfam PF10001 Uncharacterized protein conserved in bacteria (DUF2242) 53 173 1.5E-52 T 29-03-2018 IPR018718 Protein of unknown function DUF2242 CDC59_RS21870 c40f97a4c2bbca2e0cef1947836e6298 147 Pfam PF03891 Domain of unknown function (DUF333) 98 143 5.5E-19 T 29-03-2018 IPR005590 Protein of unknown function DUF333 CDC59_RS05025 a3b5f7ca8f55202341e21839d8ce7667 161 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 18 153 8.1E-19 T 29-03-2018 IPR009936 Protein of unknown function DUF1468 CDC59_RS14730 cf13ab49ee42d836e9e9390b7de86c6a 333 Pfam PF02470 MlaD protein 38 113 3.8E-13 T 29-03-2018 IPR003399 Mce/MlaD CDC59_RS08525 eacb44a84ae6f4f942ff6abdba3937e0 76 Pfam PF05751 FixH 16 57 3.5E-6 T 29-03-2018 IPR008620 Nitrogen fixation protein FixH CDC59_RS22700 8bcda37476c9f5163fd47f39fabed369 173 Pfam PF09832 Uncharacterized protein conserved in bacteria (DUF2059) 103 152 9.0E-12 T 29-03-2018 IPR018637 Domain of unknown function DUF2059 CDC59_RS00185 2d96d7f25c0ebae5b88278345f035d12 200 Gene3D G3DSA:1.20.120.80 13 186 0.0012 T 29-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CDC59_RS21140 7b6eeb1e6849f53ed26491cb5f0a5565 162 Pfam PF07681 DoxX 31 110 3.7E-17 T 29-03-2018 IPR032808 DoxX family CDC59_RS01225 e29f138c5a51eb76f2379f0dd1046ca1 328 Pfam PF05598 Transposase domain (DUF772) 51 126 2.7E-23 T 29-03-2018 IPR008490 Transposase InsH, N-terminal CDC59_RS01225 e29f138c5a51eb76f2379f0dd1046ca1 328 Pfam PF01609 Transposase DDE domain 138 312 2.4E-29 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CDC59_RS21495 b80f35a191563cda2896b9027b09ce9f 58 Pfam PF04964 Flp/Fap pilin component 8 52 9.6E-20 T 29-03-2018 IPR007047 Flp/Fap pilin component CDC59_RS11765 e8d656a7a707089687c05bc9bf67f60f 210 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 18 165 3.0E-36 T 29-03-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CDC59_RS22620 e0e28be5fc86d83b2a44b6d60d792c17 252 Pfam PF01925 Sulfite exporter TauE/SafE 8 241 2.2E-34 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CDC59_RS22820 d055f545a808862e0f93aaeec162aa0f 593 Pfam PF05819 NolX protein 91 186 2.0E-39 T 29-03-2018 IPR008718 NolX GO:0009877 CDC59_RS22820 d055f545a808862e0f93aaeec162aa0f 593 Pfam PF05819 NolX protein 179 468 7.7E-102 T 29-03-2018 IPR008718 NolX GO:0009877 CDC59_RS13180 d802d86b09b349f23166f1aa51717f0a 271 Pfam PF04403 Paraquat-inducible protein A 89 238 2.5E-39 T 29-03-2018 IPR007498 Paraquat-inducible protein A CDC59_RS18430 7332d75e22c32ae5eba4aa4d52ba345d 523 Pfam PF02543 Carbamoyltransferase N-terminus 269 312 1.5E-12 T 29-03-2018 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 CDC59_RS18430 7332d75e22c32ae5eba4aa4d52ba345d 523 Pfam PF02543 Carbamoyltransferase N-terminus 103 198 3.0E-7 T 29-03-2018 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 CDC59_RS18430 7332d75e22c32ae5eba4aa4d52ba345d 523 Pfam PF16861 Carbamoyltransferase C-terminus 355 516 6.2E-56 T 29-03-2018 IPR031730 Carbamoyltransferase, C-terminal CDC59_RS18140 65b00f9ad57ba9aeafc908ca04c8ca77 797 Pfam PF00577 Outer membrane usher protein 223 706 2.3E-23 T 29-03-2018 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 CDC59_RS04170 5f8ded10c3844fc79d9829fcae740689 144 Gene3D G3DSA:3.40.190.10 4 98 3.4E-4 T 29-03-2018 CDC59_RS10105 38a7611237971d3af9688ad1eb9a0ebe 63 Pfam PF08898 Domain of unknown function (DUF1843) 11 62 7.8E-24 T 29-03-2018 IPR014994 Domain of unknown function DUF1843