locus-tag	class	description
CJO93_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CJO93_RS00010	COG0592	DNA-directed DNA polymerase activity
CJO93_RS00025	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CJO93_RS00050	COG5297	Belongs to the glycosyl hydrolase family 6
CJO93_RS00055	COG3039	Transposase
CJO93_RS00110	COG4104	PAAR repeat-containing protein
CJO93_RS00130	COG3039	Transposase
CJO93_RS00165	COG3781	membrane
CJO93_RS00190	COG0765	amino acid transport
CJO93_RS00195	COG1126	abc transporter atp-binding protein
CJO93_RS00200	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CJO93_RS00220	COG0642	Histidine kinase
CJO93_RS00230	COG2814	Major facilitator Superfamily
CJO93_RS00245	COG1959	2 iron, 2 sulfur cluster binding
CJO93_RS00270	COG0745	RESPONSE REGULATOR receiver
CJO93_RS00275	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CJO93_RS00295	COG4251	negative regulation of phosphorylation
CJO93_RS00295	COG2203	Gaf domain
CJO93_RS00295	COG3706	GGDEF domain
CJO93_RS00295	COG5001	Diguanylate cyclase
CJO93_RS00305	COG2205	protein histidine kinase activity
CJO93_RS00310	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CJO93_RS00315	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CJO93_RS00320	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CJO93_RS00355	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CJO93_RS00365	COG1116	anion transmembrane transporter activity
CJO93_RS00375	COG1254	Belongs to the acylphosphatase family
CJO93_RS00385	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CJO93_RS00390	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CJO93_RS00405	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CJO93_RS00410	COG2894	cell division
CJO93_RS00415	COG0850	regulation of cytokinetic process
CJO93_RS00420	COG0737	Belongs to the 5'-nucleotidase family
CJO93_RS00430	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CJO93_RS00455	COG2154	pterin-4-alpha-carbinolamine dehydratase
CJO93_RS00460	COG3186	Phenylalanine-4-hydroxylase
CJO93_RS00475	COG2423	ornithine cyclodeaminase activity
CJO93_RS00480	COG3047	cAMP biosynthetic process
CJO93_RS00490	COG2217	Heavy metal translocating P-type atpase
CJO93_RS00495	COG0789	Transcriptional regulator
CJO93_RS00500	COG2267	carboxylic ester hydrolase activity
CJO93_RS00565	COG3530	Putative quorum-sensing-regulated virulence factor
CJO93_RS00570	COG0583	DNA-binding transcription factor activity
CJO93_RS00590	COG0445	tRNA wobble uridine modification
CJO93_RS00595	COG0357	Ribosomal RNA small subunit methyltransferase G
CJO93_RS00600	COG1192	Involved in chromosome partitioning
CJO93_RS00605	COG1475	DNA binding
CJO93_RS00615	COG0356	it plays a direct role in the translocation of protons across the membrane
CJO93_RS00625	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CJO93_RS00630	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CJO93_RS00635	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CJO93_RS00640	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CJO93_RS00645	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CJO93_RS00650	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CJO93_RS00665	COG1832	CoA-binding protein
CJO93_RS00685	COG0625	glutathione transferase activity
CJO93_RS00715	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CJO93_RS00720	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CJO93_RS00725	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CJO93_RS00725	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CJO93_RS00725	COG0506	proline dehydrogenase activity
CJO93_RS00730	COG0683	leucine binding
CJO93_RS00740	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CJO93_RS00745	COG1297	OPT oligopeptide transporter protein
CJO93_RS00750	COG1760	l-serine dehydratase
CJO93_RS00755	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CJO93_RS00755	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CJO93_RS00760	COG0509	glycine decarboxylation via glycine cleavage system
CJO93_RS00765	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CJO93_RS00785	COG0210	DNA helicase
CJO93_RS00805	COG2197	response regulator
CJO93_RS00810	COG3916	Acyl-homoserine-lactone synthase
CJO93_RS00820	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CJO93_RS00825	COG2084	Dehydrogenase
CJO93_RS00830	COG3622	Belongs to the hyi family
CJO93_RS00835	COG3960	tartronate-semialdehyde synthase activity
CJO93_RS00840	COG0583	DNA-binding transcription factor activity
CJO93_RS00855	COG1739	Uncharacterized protein family UPF0029
CJO93_RS00865	COG1301	dicarboxylic acid transport
CJO93_RS00870	COG4266	Belongs to the allantoicase family
CJO93_RS00880	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CJO93_RS00910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CJO93_RS00925	COG0792	nuclease activity
CJO93_RS00940	COG0446	pyridine nucleotide-disulphide oxidoreductase
CJO93_RS00950	COG4654	Cytochrome c, class I
CJO93_RS00975	COG2010	Cytochrome c
CJO93_RS00980	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CJO93_RS00985	COG0737	Belongs to the 5'-nucleotidase family
CJO93_RS01010	COG3039	Transposase
CJO93_RS01055	COG3311	Transcriptional regulator
CJO93_RS01165	COG3209	COG3209 Rhs family protein
CJO93_RS01180	COG3436	PFAM IS66 Orf2 family protein
CJO93_RS01220	COG4942	peptidase
CJO93_RS01265	COG4974	Belongs to the 'phage' integrase family
CJO93_RS01290	COG3210	domain, Protein
CJO93_RS01300	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CJO93_RS01370	COG3039	Transposase
CJO93_RS01395	COG0529	Catalyzes the synthesis of activated sulfate
CJO93_RS01410	COG0457	Tetratricopeptide repeat
CJO93_RS01435	COG0493	'glutamate synthase
CJO93_RS01450	COG3385	transposase activity
CJO93_RS01455	COG1278	Cold shock
CJO93_RS01475	COG3039	Transposase
CJO93_RS01535	COG5001	Diguanylate cyclase
CJO93_RS01535	COG4251	negative regulation of phosphorylation
CJO93_RS01535	COG3706	GGDEF domain
CJO93_RS01535	COG2203	Gaf domain
CJO93_RS01550	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CJO93_RS01560	COG1028	Short-chain dehydrogenase reductase Sdr
CJO93_RS01570	COG0840	transmembrane signaling receptor activity
CJO93_RS01595	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CJO93_RS01605	COG3284	Transcriptional regulator
CJO93_RS01615	COG4303	Ethanolamine ammonia lyase large subunit
CJO93_RS01620	COG4302	ethanolamine ammonia-lyase activity
CJO93_RS01625	COG2925	Exonuclease
CJO93_RS01735	COG1522	sequence-specific DNA binding
CJO93_RS01745	COG1404	Belongs to the peptidase S8 family
CJO93_RS01755	COG3385	transposase activity
CJO93_RS01775	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CJO93_RS01775	COG0475	glutathione-regulated potassium exporter activity
CJO93_RS01805	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CJO93_RS01810	COG3385	transposase activity
CJO93_RS01820	COG0745	RESPONSE REGULATOR receiver
CJO93_RS01875	COG2197	response regulator
CJO93_RS01880	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CJO93_RS01915	COG2814	Major facilitator Superfamily
CJO93_RS01920	COG0668	transmembrane transport
CJO93_RS01935	COG0745	RESPONSE REGULATOR receiver
CJO93_RS01940	COG2205	protein histidine kinase activity
CJO93_RS01970	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CJO93_RS01975	COG2336	PFAM SpoVT AbrB
CJO93_RS01995	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CJO93_RS02010	COG0395	ABC-type sugar transport system, permease component
CJO93_RS02020	COG3842	ATPase activity
CJO93_RS02025	COG3842	ATPase activity
CJO93_RS02035	COG1349	DNA-binding transcription factor activity
CJO93_RS02085	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CJO93_RS02105	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CJO93_RS02110	COG0081	regulation of translation
CJO93_RS02115	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CJO93_RS02120	COG0222	ribosome binding
CJO93_RS02125	COG0085	RNA polymerase activity
CJO93_RS02130	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CJO93_RS02135	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
CJO93_RS02140	COG3234	Protein of unknown function (DUF1175)
CJO93_RS02145	COG2373	Large extracellular alpha-helical protein
CJO93_RS02150	COG5445	Predicted secreted protein (DUF2300)
CJO93_RS02155	COG4676	Protein conserved in bacteria
CJO93_RS02160	COG4676	Protein conserved in bacteria
CJO93_RS02170	COG0514	ATP-dependent DNA helicase (RecQ)
CJO93_RS02175	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CJO93_RS02180	COG0049	tRNA binding
CJO93_RS02185	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CJO93_RS02190	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CJO93_RS02195	COG0051	transcription antitermination factor activity, RNA binding
CJO93_RS02200	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CJO93_RS02205	COG0088	Forms part of the polypeptide exit tunnel
CJO93_RS02210	COG0089	rRNA binding
CJO93_RS02215	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CJO93_RS02220	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CJO93_RS02225	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CJO93_RS02230	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CJO93_RS02235	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CJO93_RS02240	COG0255	Belongs to the universal ribosomal protein uL29 family
CJO93_RS02245	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CJO93_RS02250	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CJO93_RS02255	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CJO93_RS02260	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CJO93_RS02265	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CJO93_RS02270	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CJO93_RS02275	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CJO93_RS02280	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CJO93_RS02285	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CJO93_RS02290	COG1841	ribosomal large subunit assembly
CJO93_RS02295	COG0200	Binds to the 23S rRNA
CJO93_RS02300	COG0201	protein transport
CJO93_RS02305	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CJO93_RS02310	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CJO93_RS02315	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CJO93_RS02320	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CJO93_RS02325	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CJO93_RS02330	COG0202	RNA polymerase activity
CJO93_RS02335	COG0203	ribosomal protein L17
CJO93_RS02345	COG4232	protein-disulfide reductase activity
CJO93_RS02355	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CJO93_RS02365	COG1333	cytochrome c biogenesis protein
CJO93_RS02370	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CJO93_RS02390	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CJO93_RS02395	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CJO93_RS02410	COG1965	Belongs to the frataxin family
CJO93_RS02415	COG3385	transposase activity
CJO93_RS02450	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CJO93_RS02455	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CJO93_RS02460	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CJO93_RS02465	COG3047	cAMP biosynthetic process
CJO93_RS02475	COG0070	glutamate synthase
CJO93_RS02475	COG0069	glutamate synthase activity
CJO93_RS02475	COG0067	glutamate synthase
CJO93_RS02490	COG1127	ABC transporter
CJO93_RS02495	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CJO93_RS02500	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CJO93_RS02520	COG1131	(ABC) transporter
CJO93_RS02535	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CJO93_RS02540	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CJO93_RS02545	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CJO93_RS02550	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CJO93_RS02555	COG0131	Imidazoleglycerol-phosphate dehydratase
CJO93_RS02560	COG2095	MarC family integral membrane protein
CJO93_RS02565	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CJO93_RS02570	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CJO93_RS02575	COG0107	imidazoleglycerol-phosphate synthase activity
CJO93_RS02580	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CJO93_RS02585	COG0140	phosphoribosyl-ATP diphosphatase activity
CJO93_RS02595	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CJO93_RS02600	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CJO93_RS02605	COG0805	protein transport
CJO93_RS02610	COG3385	transposase activity
CJO93_RS02615	COG3842	ATPase activity
CJO93_RS02625	COG1840	ABC-type Fe3 transport system, periplasmic component
CJO93_RS02645	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CJO93_RS02650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CJO93_RS02655	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CJO93_RS02660	COG1970	mechanosensitive ion channel activity
CJO93_RS02665	COG0723	plastoquinol--plastocyanin reductase activity
CJO93_RS02670	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CJO93_RS02675	COG2857	Cytochrome c1
CJO93_RS02680	COG0625	glutathione transferase activity
CJO93_RS02685	COG2969	positive regulation of protein catabolic process
CJO93_RS02710	COG0405	Gamma-glutamyltransferase
CJO93_RS02715	COG4774	siderophore transport
CJO93_RS02720	COG3712	iron ion homeostasis
CJO93_RS02730	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CJO93_RS02745	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CJO93_RS02750	COG0488	(ABC) transporter
CJO93_RS02770	COG3416	Protein conserved in bacteria
CJO93_RS02770	COG2943	transferase activity, transferring hexosyl groups
CJO93_RS02775	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CJO93_RS02790	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CJO93_RS02795	COG2890	protein-(glutamine-N5) methyltransferase activity
CJO93_RS02805	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CJO93_RS02810	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CJO93_RS02820	COG0012	GTP binding
CJO93_RS02845	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CJO93_RS02855	COG0604	alcohol dehydrogenase
CJO93_RS02865	COG1289	transmembrane transporter activity
CJO93_RS02880	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CJO93_RS02890	COG0134	indole-3-glycerol-phosphate synthase activity
CJO93_RS02895	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CJO93_RS02905	COG0512	Glutamine amidotransferase of anthranilate synthase
CJO93_RS02915	COG0546	phosphoglycolate phosphatase activity
CJO93_RS02920	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CJO93_RS02925	COG2967	ApaG domain
CJO93_RS02945	COG2050	protein possibly involved in aromatic compounds catabolism
CJO93_RS02950	COG1024	Enoyl-CoA hydratase
CJO93_RS02955	COG1024	Enoyl-CoA hydratase
CJO93_RS02985	COG1473	amidohydrolase
CJO93_RS02995	COG0601	transmembrane transport
CJO93_RS03000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CJO93_RS03005	COG0444	Belongs to the ABC transporter superfamily
CJO93_RS03010	COG4608	Belongs to the ABC transporter superfamily
CJO93_RS03020	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CJO93_RS03020	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CJO93_RS03025	COG1105	Belongs to the carbohydrate kinase PfkB family
CJO93_RS03030	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CJO93_RS03030	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CJO93_RS03035	COG1609	Transcriptional regulator
CJO93_RS03040	COG0243	molybdopterin cofactor binding
CJO93_RS03050	COG0318	PFAM AMP-dependent synthetase and ligase
CJO93_RS03055	COG0477	Major facilitator Superfamily
CJO93_RS03060	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CJO93_RS03065	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
CJO93_RS03070	COG2001	Belongs to the MraZ family
CJO93_RS03075	COG0275	rRNA processing
CJO93_RS03090	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CJO93_RS03095	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CJO93_RS03100	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CJO93_RS03105	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CJO93_RS03120	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CJO93_RS03125	COG1181	Belongs to the D-alanine--D-alanine ligase family
CJO93_RS03130	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CJO93_RS03145	COG0678	peroxiredoxin activity
CJO93_RS03150	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CJO93_RS03160	COG0739	heme binding
CJO93_RS03165	COG0653	protein targeting
CJO93_RS03170	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CJO93_RS03180	COG0494	nUDIX hydrolase
CJO93_RS03185	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CJO93_RS03190	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CJO93_RS03195	COG0237	dephospho-CoA kinase activity
CJO93_RS03205	COG1459	type II secretion system
CJO93_RS03215	COG4536	flavin adenine dinucleotide binding
CJO93_RS03225	COG0142	geranyltranstransferase activity
CJO93_RS03230	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CJO93_RS03235	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CJO93_RS03240	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CJO93_RS03245	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CJO93_RS03255	COG0494	nUDIX hydrolase
CJO93_RS03260	COG0442	prolyl-tRNA aminoacylation
CJO93_RS03265	COG0741	lytic transglycosylase activity
CJO93_RS03275	COG2095	MarC family integral membrane protein
CJO93_RS03280	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CJO93_RS03285	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CJO93_RS03310	COG3023	N-Acetylmuramoyl-L-alanine amidase
CJO93_RS03335	COG1522	sequence-specific DNA binding
CJO93_RS03345	COG0840	transmembrane signaling receptor activity
CJO93_RS03390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CJO93_RS03395	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CJO93_RS03405	COG2264	protein methyltransferase activity
CJO93_RS03415	COG0511	ligase activity, forming carbon-carbon bonds
CJO93_RS03420	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CJO93_RS03425	COG3118	belongs to the thioredoxin family
CJO93_RS03435	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CJO93_RS03440	COG3150	esterase
CJO93_RS03445	COG3161	chorismate lyase activity
CJO93_RS03450	COG0557	exoribonuclease II activity
CJO93_RS03460	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CJO93_RS03465	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CJO93_RS03480	COG0284	orotidine-5'-phosphate decarboxylase activity
CJO93_RS03490	COG1546	Belongs to the CinA family
CJO93_RS03490	COG1058	Belongs to the CinA family
CJO93_RS03495	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CJO93_RS03505	COG0280	phosphate acetyltransferase
CJO93_RS03505	COG0281	malic enzyme
CJO93_RS03525	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CJO93_RS03535	COG0583	DNA-binding transcription factor activity
CJO93_RS03540	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CJO93_RS03555	COG1129	ABC transporter
CJO93_RS03575	COG1028	Short-chain dehydrogenase reductase Sdr
CJO93_RS03580	COG0800	Aldolase
CJO93_RS03585	COG4948	Mandelate Racemase Muconate Lactonizing
CJO93_RS03590	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CJO93_RS03595	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CJO93_RS03600	COG0583	DNA-binding transcription factor activity
CJO93_RS03605	COG0735	belongs to the Fur family
CJO93_RS03610	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CJO93_RS03615	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CJO93_RS03620	COG0495	leucyl-tRNA aminoacylation
CJO93_RS03630	COG1466	dna polymerase III delta subunit
CJO93_RS03635	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CJO93_RS03640	COG1981	membrane
CJO93_RS03650	COG2204	response regulator
CJO93_RS03655	COG4191	Histidine kinase
CJO93_RS03660	COG4191	Histidine kinase
CJO93_RS03685	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CJO93_RS03725	COG0482	sulfurtransferase activity
CJO93_RS03730	COG0069	glutamate synthase activity
CJO93_RS03735	COG0625	glutathione transferase activity
CJO93_RS03745	COG3038	cytochrome b561
CJO93_RS03750	COG2353	YceI-like domain
CJO93_RS03755	COG2353	YceI-like domain
CJO93_RS03760	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CJO93_RS03765	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CJO93_RS03770	COG1862	Preprotein translocase
CJO93_RS03775	COG0343	queuine tRNA-ribosyltransferase activity
CJO93_RS03780	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CJO93_RS03785	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CJO93_RS03825	COG1522	sequence-specific DNA binding
CJO93_RS03830	COG1473	amidohydrolase
CJO93_RS03835	COG1819	glycosyl
CJO93_RS03855	COG3039	Transposase
CJO93_RS03900	COG1278	Cold shock
CJO93_RS03990	COG0783	Belongs to the Dps family
CJO93_RS03995	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CJO93_RS04055	COG0386	Belongs to the glutathione peroxidase family
CJO93_RS04075	COG1346	cytolysis
CJO93_RS04080	COG1380	Effector of murein hydrolase LrgA
CJO93_RS04085	COG0247	lactate metabolic process
CJO93_RS04090	COG0277	FAD linked oxidase domain protein
CJO93_RS04095	COG0277	FAD linked oxidase domain protein
CJO93_RS04100	COG0583	DNA-binding transcription factor activity
CJO93_RS04105	COG0277	FAD linked oxidase domain protein
CJO93_RS04110	COG2096	Adenosyltransferase
CJO93_RS04115	COG0668	transmembrane transport
CJO93_RS04125	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CJO93_RS04130	COG0312	modulator of DNA gyrase
CJO93_RS04135	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CJO93_RS04145	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CJO93_RS04160	COG1404	Belongs to the peptidase S8 family
CJO93_RS04170	COG0497	DNA recombination
CJO93_RS04175	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CJO93_RS04180	COG1420	regulation of RNA biosynthetic process
CJO93_RS04195	COG2986	histidine ammonia-lyase
CJO93_RS04200	COG0010	Belongs to the arginase family
CJO93_RS04205	COG1228	amidohydrolase
CJO93_RS04210	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CJO93_RS04230	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CJO93_RS04240	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CJO93_RS04245	COG0443	Heat shock 70 kDa protein
CJO93_RS04250	COG0484	heat shock protein binding
CJO93_RS04255	COG0512	Glutamine amidotransferase of anthranilate synthase
CJO93_RS04255	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CJO93_RS04260	COG1122	ATPase activity
CJO93_RS04265	COG4662	Binding-protein-dependent transport system inner membrane component
CJO93_RS04270	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CJO93_RS04280	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CJO93_RS04295	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CJO93_RS04300	COG0628	permease
CJO93_RS04305	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CJO93_RS04320	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CJO93_RS04320	COG2169	Transcriptional regulator
CJO93_RS04340	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CJO93_RS04340	COG2169	Transcriptional regulator
CJO93_RS04345	COG0456	acetyltransferase
CJO93_RS04350	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CJO93_RS04355	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CJO93_RS04360	COG3008	intermembrane lipid transfer
CJO93_RS04375	COG0586	Pfam SNARE associated Golgi protein
CJO93_RS04390	COG0268	Binds directly to 16S ribosomal RNA
CJO93_RS04400	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CJO93_RS04425	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CJO93_RS04430	COG1666	GTP binding
CJO93_RS04440	COG2366	antibiotic biosynthetic process
CJO93_RS04445	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CJO93_RS04455	COG4974	Belongs to the 'phage' integrase family
CJO93_RS04470	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CJO93_RS04475	COG0802	atpase or kinase
CJO93_RS04480	COG0860	N-Acetylmuramoyl-L-alanine amidase
CJO93_RS04490	COG0583	DNA-binding transcription factor activity
CJO93_RS04510	COG0563	adenylate kinase activity
CJO93_RS04515	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CJO93_RS04520	COG2835	tetraacyldisaccharide 4'-kinase activity
CJO93_RS04525	COG1663	tetraacyldisaccharide 4'-kinase activity
CJO93_RS04535	COG0811	peptide transport
CJO93_RS04540	COG1570	exodeoxyribonuclease VII activity
CJO93_RS04545	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CJO93_RS04590	COG2610	gluconate transmembrane transporter activity
CJO93_RS04625	COG1473	amidohydrolase
CJO93_RS04660	COG1028	Short-chain dehydrogenase reductase Sdr
CJO93_RS04665	COG2321	neutral zinc metallopeptidase
CJO93_RS04680	COG2259	Doxx family
CJO93_RS04690	COG0583	DNA-binding transcription factor activity
CJO93_RS04695	COG0583	DNA-binding transcription factor activity
CJO93_RS04715	COG1858	cytochrome C peroxidase
CJO93_RS04750	COG1278	Cold shock
CJO93_RS04755	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CJO93_RS04760	COG0542	response to heat
CJO93_RS04765	COG0756	dUTP diphosphatase activity
CJO93_RS04770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CJO93_RS04775	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CJO93_RS04785	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CJO93_RS04790	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CJO93_RS04795	COG0196	riboflavin kinase activity
CJO93_RS04800	COG0784	Response regulator, receiver
CJO93_RS04800	COG5002	protein histidine kinase activity
CJO93_RS04810	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CJO93_RS04815	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CJO93_RS04815	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CJO93_RS04825	COG1511	domain protein
CJO93_RS04825	COG3264	Mechanosensitive ion channel
CJO93_RS04835	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CJO93_RS04845	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CJO93_RS04850	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CJO93_RS04855	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CJO93_RS04860	COG2003	Belongs to the UPF0758 family
CJO93_RS04865	COG1047	Peptidyl-prolyl cis-trans
CJO93_RS04870	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CJO93_RS04905	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CJO93_RS04940	COG2084	Dehydrogenase
CJO93_RS04950	COG0583	DNA-binding transcription factor activity
CJO93_RS04960	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CJO93_RS04970	COG0175	sulfate reduction
CJO93_RS04980	COG2895	sulfate adenylyltransferase (ATP) activity
CJO93_RS05010	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CJO93_RS05025	COG3385	transposase activity
CJO93_RS05030	COG0129	dihydroxy-acid dehydratase activity
CJO93_RS05035	COG0583	DNA-binding transcription factor activity
CJO93_RS05040	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CJO93_RS05070	COG4206	TonB-dependent receptor
CJO93_RS05080	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CJO93_RS05085	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CJO93_RS05090	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CJO93_RS05100	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CJO93_RS05110	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CJO93_RS05120	COG1492	cobalamin metabolic process
CJO93_RS05135	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CJO93_RS05140	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CJO93_RS05155	COG2911	Protein conserved in bacteria
CJO93_RS05165	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CJO93_RS05165	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CJO93_RS05170	COG3047	cAMP biosynthetic process
CJO93_RS05170	COG2885	chlorophyll binding
CJO93_RS05175	COG0489	protein tyrosine kinase activity
CJO93_RS05205	COG0243	molybdopterin cofactor binding
CJO93_RS05205	COG3383	formate dehydrogenase (NAD+) activity
CJO93_RS05210	COG0437	4 iron, 4 sulfur cluster binding
CJO93_RS05230	COG2032	superoxide dismutase activity
CJO93_RS05235	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CJO93_RS05240	COG0717	Belongs to the dCTP deaminase family
CJO93_RS05285	COG0165	Argininosuccinate lyase
CJO93_RS05310	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CJO93_RS05315	COG0181	hydroxymethylbilane synthase activity
CJO93_RS05340	COG2271	Major facilitator Superfamily
CJO93_RS05355	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CJO93_RS05395	COG0492	ferredoxin-NADP+ reductase activity
CJO93_RS05400	COG1674	ftsk spoiiie
CJO93_RS05405	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CJO93_RS05415	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CJO93_RS05420	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CJO93_RS05445	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CJO93_RS05455	COG0582	viral genome integration into host DNA
CJO93_RS05465	COG1846	Transcriptional regulator
CJO93_RS05475	COG2814	Major facilitator Superfamily
CJO93_RS05485	COG1028	Short-chain dehydrogenase reductase Sdr
CJO93_RS05500	COG2197	response regulator
CJO93_RS05555	COG2165	general secretion pathway protein
CJO93_RS05625	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CJO93_RS05670	COG1253	flavin adenine dinucleotide binding
CJO93_RS05710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CJO93_RS05725	COG0765	amino acid transport
CJO93_RS05730	COG0765	amino acid transport
CJO93_RS05735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CJO93_RS05745	COG1414	Transcriptional regulator
CJO93_RS05755	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CJO93_RS05770	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CJO93_RS05775	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CJO93_RS05790	COG0411	ABC transporter
CJO93_RS05800	COG0683	leucine binding
CJO93_RS05815	COG2342	PFAM TM1410 hypothetical-related protein
CJO93_RS05825	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CJO93_RS05840	COG0525	valine-tRNA ligase activity
CJO93_RS05845	COG0210	DNA helicase
CJO93_RS05855	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CJO93_RS05865	COG1611	Belongs to the LOG family
CJO93_RS05870	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CJO93_RS05870	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CJO93_RS05875	COG1252	NADH dehydrogenase
CJO93_RS05880	COG0412	Dienelactone hydrolase
CJO93_RS05890	COG3385	transposase activity
CJO93_RS05910	COG1722	exodeoxyribonuclease VII activity
CJO93_RS05915	COG0142	geranyltranstransferase activity
CJO93_RS05920	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CJO93_RS05925	COG1469	GTP cyclohydrolase I activity
CJO93_RS05930	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CJO93_RS05935	COG2081	HI0933 family
CJO93_RS05940	COG1610	YqeY-like protein
CJO93_RS05960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CJO93_RS05970	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CJO93_RS05970	COG0426	domain, Protein
CJO93_RS05975	COG0513	Belongs to the DEAD box helicase family
CJO93_RS05980	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CJO93_RS05985	COG0583	DNA-binding transcription factor activity
CJO93_RS05990	COG1741	Belongs to the pirin family
CJO93_RS06000	COG1054	Belongs to the UPF0176 family
CJO93_RS06020	COG0463	Glycosyl transferase, family 2
CJO93_RS06030	COG1132	(ABC) transporter
CJO93_RS06050	COG1530	ribonuclease E activity
CJO93_RS06055	COG0424	maF-like protein
CJO93_RS06060	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CJO93_RS06065	COG0799	negative regulation of ribosome biogenesis
CJO93_RS06075	COG0408	coproporphyrinogen oxidase activity
CJO93_RS06080	COG0151	Belongs to the GarS family
CJO93_RS06085	COG0217	transcriptional regulatory protein
CJO93_RS06090	COG0433	COG0433 Predicted ATPase
CJO93_RS06095	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CJO93_RS06100	COG0697	spore germination
CJO93_RS06105	COG1028	Short-chain dehydrogenase reductase Sdr
CJO93_RS06110	COG1803	Methylglyoxal synthase
CJO93_RS06165	COG3845	ABC transporter
CJO93_RS06170	COG2814	Major facilitator Superfamily
CJO93_RS06175	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CJO93_RS06180	COG1984	allophanate hydrolase subunit 2
CJO93_RS06185	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CJO93_RS06200	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CJO93_RS06205	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CJO93_RS06220	COG1234	tRNA 3'-trailer cleavage
CJO93_RS06230	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CJO93_RS06235	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CJO93_RS06240	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CJO93_RS06250	COG4991	sh3 domain protein
CJO93_RS06250	COG3064	Membrane
CJO93_RS06250	COG0515	serine threonine protein kinase
CJO93_RS06255	COG1561	YicC-like family, N-terminal region
CJO93_RS06260	COG0194	GDP metabolic process
CJO93_RS06265	COG1758	RNA polymerase activity
CJO93_RS06270	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CJO93_RS06300	COG1652	LysM domain
CJO93_RS06310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CJO93_RS06335	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CJO93_RS06340	COG3842	ATPase activity
CJO93_RS06350	COG1733	regulation of RNA biosynthetic process
CJO93_RS06355	COG0166	Belongs to the GPI family
CJO93_RS06355	COG0166	Belongs to the GPI family
CJO93_RS06360	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CJO93_RS06385	COG0246	Mannitol dehydrogenase
CJO93_RS06390	COG1070	Carbohydrate kinase
CJO93_RS06395	COG2390	Transcriptional regulator
CJO93_RS06405	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CJO93_RS06410	COG0308	aminopeptidase N
CJO93_RS06420	COG0280	phosphate acetyltransferase
CJO93_RS06420	COG0281	malic enzyme
CJO93_RS06430	COG3195	allantoin biosynthetic process
CJO93_RS06430	COG3648	Uricase
CJO93_RS06445	COG2233	PERMEase
CJO93_RS06455	COG2351	hydroxyisourate hydrolase activity
CJO93_RS06470	COG3039	Transposase
CJO93_RS06475	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CJO93_RS06480	COG2271	Major facilitator Superfamily
CJO93_RS06485	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CJO93_RS06500	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CJO93_RS06510	COG1126	abc transporter atp-binding protein
CJO93_RS06515	COG0765	amino acid transport
CJO93_RS06520	COG0765	amino acid transport
CJO93_RS06530	COG2186	Transcriptional regulator
CJO93_RS06550	COG2119	membrane
CJO93_RS06555	COG0402	S-adenosylhomocysteine deaminase activity
CJO93_RS06560	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CJO93_RS06570	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CJO93_RS06595	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CJO93_RS06620	COG1309	transcriptional regulator
CJO93_RS06630	COG0438	transferase activity, transferring glycosyl groups
CJO93_RS06665	COG0028	Belongs to the TPP enzyme family
CJO93_RS06675	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CJO93_RS06680	COG0688	phosphatidylethanolamine metabolic process
CJO93_RS06685	COG1183	phosphatidylcholine synthase activity
CJO93_RS06690	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CJO93_RS06700	COG0683	leucine binding
CJO93_RS06705	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CJO93_RS06710	COG1185	polyribonucleotide nucleotidyltransferase activity
CJO93_RS06725	COG0149	triose-phosphate isomerase activity
CJO93_RS06730	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CJO93_RS06740	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CJO93_RS06745	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CJO93_RS06750	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CJO93_RS06755	COG0649	NAD binding
CJO93_RS06770	COG1034	ATP synthesis coupled electron transport
CJO93_RS06775	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CJO93_RS06780	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CJO93_RS06790	COG0713	ATP synthesis coupled electron transport
CJO93_RS06805	COG1007	ATP synthesis coupled electron transport
CJO93_RS06840	COG1960	acyl-CoA dehydrogenase activity
CJO93_RS06845	COG1012	belongs to the aldehyde dehydrogenase family
CJO93_RS06845	COG2030	dehydratase
CJO93_RS06880	COG0829	nickel cation binding
CJO93_RS06885	COG0831	urea catabolic process
CJO93_RS06895	COG0832	Belongs to the urease beta subunit family
CJO93_RS06900	COG0804	urea catabolic process
CJO93_RS06905	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CJO93_RS06910	COG0830	nickel cation binding
CJO93_RS06915	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CJO93_RS06945	COG0625	glutathione transferase activity
CJO93_RS06950	COG1960	acyl-CoA dehydrogenase activity
CJO93_RS06980	COG1024	Enoyl-CoA hydratase
CJO93_RS06985	COG1250	3-hydroxyacyl-CoA dehydrogenase
CJO93_RS06990	COG0625	glutathione transferase activity
CJO93_RS06995	COG0436	Aminotransferase
CJO93_RS07005	COG3022	response to hydroperoxide
CJO93_RS07010	COG2866	Carboxypeptidase
CJO93_RS07020	COG0747	negative chemotaxis
CJO93_RS07035	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CJO93_RS07060	COG0039	L-malate dehydrogenase activity
CJO93_RS07065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CJO93_RS07075	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CJO93_RS07080	COG1053	succinate dehydrogenase
CJO93_RS07085	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CJO93_RS07090	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CJO93_RS07095	COG0372	Belongs to the citrate synthase family
CJO93_RS07100	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CJO93_RS07105	COG0066	3-isopropylmalate dehydratase activity
CJO93_RS07110	COG0473	3-isopropylmalate dehydrogenase activity
CJO93_RS07125	COG0101	tRNA pseudouridine synthase activity
CJO93_RS07130	COG0135	phosphoribosylanthranilate isomerase activity
CJO93_RS07135	COG0133	tryptophan synthase activity
CJO93_RS07145	COG0159	tryptophan synthase activity
CJO93_RS07150	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CJO93_RS07155	COG0285	dihydrofolate synthase activity
CJO93_RS07175	COG0842	Transport permease protein
CJO93_RS07180	COG1131	(ABC) transporter
CJO93_RS07210	COG3193	protein, possibly involved in utilization of glycolate and propanediol
CJO93_RS07255	COG1301	dicarboxylic acid transport
CJO93_RS07260	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CJO93_RS07275	COG0697	spore germination
CJO93_RS07280	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CJO93_RS07285	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CJO93_RS07305	COG2197	response regulator
CJO93_RS07310	COG0840	transmembrane signaling receptor activity
CJO93_RS07350	COG0747	negative chemotaxis
CJO93_RS07370	COG0601	transmembrane transport
CJO93_RS07375	COG2072	flavoprotein involved in K transport
CJO93_RS07420	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CJO93_RS07435	COG0582	viral genome integration into host DNA
CJO93_RS07465	COG0656	L-ascorbic acid biosynthetic process
CJO93_RS07470	COG2304	oxidoreductase activity
CJO93_RS07485	COG0589	response to stress
CJO93_RS07520	COG0328	RNA-DNA hybrid ribonuclease activity
CJO93_RS07525	COG2226	methyltransferase
CJO93_RS07530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CJO93_RS07535	COG1388	LysM domain
CJO93_RS07535	COG0741	lytic transglycosylase activity
CJO93_RS07540	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CJO93_RS07545	COG0505	Belongs to the CarA family
CJO93_RS07555	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CJO93_RS07560	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CJO93_RS07570	COG1534	Rna-binding protein
CJO93_RS07575	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CJO93_RS07580	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CJO93_RS07585	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CJO93_RS07590	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CJO93_RS07595	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CJO93_RS07600	COG0573	inorganic phosphate transmembrane transporter activity
CJO93_RS07605	COG0581	inorganic phosphate transmembrane transporter activity
CJO93_RS07610	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CJO93_RS07620	COG0745	RESPONSE REGULATOR receiver
CJO93_RS07630	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CJO93_RS07635	COG0248	Ppx GppA phosphatase
CJO93_RS07660	COG0730	response to heat
CJO93_RS07670	COG0640	Transcriptional regulator
CJO93_RS07745	COG0277	FAD linked oxidase domain protein
CJO93_RS07760	COG1295	ribonuclease BN
CJO93_RS07785	COG0477	Major facilitator Superfamily
CJO93_RS07790	COG0545	Peptidyl-prolyl cis-trans isomerase
CJO93_RS07795	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CJO93_RS07805	COG1028	Short-chain dehydrogenase reductase Sdr
CJO93_RS07810	COG4566	intracellular signal transduction
CJO93_RS07825	COG1028	Short-chain dehydrogenase reductase Sdr
CJO93_RS07835	COG0251	oxidation-reduction process
CJO93_RS07840	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CJO93_RS07850	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CJO93_RS07855	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CJO93_RS07860	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CJO93_RS07865	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CJO93_RS07870	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CJO93_RS07875	COG0072	phenylalanine-tRNA ligase activity
CJO93_RS07875	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CJO93_RS07880	COG0776	regulation of translation
CJO93_RS07910	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CJO93_RS07915	COG0531	amino acid
CJO93_RS07935	COG1846	Transcriptional regulator
CJO93_RS07945	COG0402	S-adenosylhomocysteine deaminase activity
CJO93_RS07950	COG0339	signal peptide processing
CJO93_RS07955	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CJO93_RS07960	COG4566	intracellular signal transduction
CJO93_RS07975	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CJO93_RS07980	COG0508	dehydrogenase complex catalyzes the overall conversion of
CJO93_RS07990	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CJO93_RS08005	COG0123	including yeast histone deacetylase and acetoin utilization protein
CJO93_RS08030	COG1414	Transcriptional regulator
CJO93_RS08055	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CJO93_RS08060	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CJO93_RS08080	COG0167	dihydroorotate dehydrogenase activity
CJO93_RS08090	COG3158	transport of potassium into the cell
CJO93_RS08100	COG2183	response to ionizing radiation
CJO93_RS08115	COG1199	ATP-dependent helicase activity
CJO93_RS08125	COG0564	pseudouridine synthase activity
CJO93_RS08140	COG3243	poly(R)-hydroxyalkanoic acid synthase
CJO93_RS08145	COG0183	Belongs to the thiolase family
CJO93_RS08150	COG1028	Short-chain dehydrogenase reductase Sdr
CJO93_RS08160	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CJO93_RS08165	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CJO93_RS08170	COG0183	Belongs to the thiolase family
CJO93_RS08185	COG0560	Phosphoserine phosphatase
CJO93_RS08195	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CJO93_RS08200	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CJO93_RS08205	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CJO93_RS08210	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CJO93_RS08215	COG0450	alkyl hydroperoxide reductase
CJO93_RS08245	COG1562	ergosterol biosynthetic process
CJO93_RS08250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CJO93_RS08265	COG0582	viral genome integration into host DNA
CJO93_RS08275	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CJO93_RS08330	COG1396	sequence-specific DNA binding
CJO93_RS08440	COG4386	tail sheath protein
CJO93_RS08470	COG4228	DNA circulation
CJO93_RS08485	COG4381	Mu-like prophage protein gp46
CJO93_RS08540	COG1652	LysM domain
CJO93_RS08550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CJO93_RS08550	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CJO93_RS08555	COG0544	peptidyl-prolyl cis-trans isomerase activity
CJO93_RS08560	COG0740	serine-type endopeptidase activity
CJO93_RS08565	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CJO93_RS08570	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CJO93_RS08575	COG0776	regulation of translation
CJO93_RS08590	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CJO93_RS08595	COG3385	transposase activity
CJO93_RS08610	COG4181	ATPase activity
CJO93_RS08615	COG0166	Belongs to the GPI family
CJO93_RS08620	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CJO93_RS08630	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CJO93_RS08630	COG0047	phosphoribosylformylglycinamidine synthase activity
CJO93_RS08650	COG0535	radical SAM domain protein
CJO93_RS08670	COG0583	DNA-binding transcription factor activity
CJO93_RS08675	COG1028	Short-chain dehydrogenase reductase Sdr
CJO93_RS08685	COG1176	ABC-type spermidine putrescine transport system, permease component I
CJO93_RS08695	COG3842	ATPase activity
CJO93_RS08700	COG0642	Histidine kinase
CJO93_RS08710	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CJO93_RS08715	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CJO93_RS08745	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CJO93_RS08755	COG2917	probably involved in intracellular septation
CJO93_RS08760	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CJO93_RS08765	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CJO93_RS08770	COG0318	PFAM AMP-dependent synthetase and ligase
CJO93_RS08780	COG0559	Belongs to the binding-protein-dependent transport system permease family
CJO93_RS08810	COG0833	amino acid
CJO93_RS08815	COG0833	amino acid
CJO93_RS08825	COG1335	isochorismatase
CJO93_RS08830	COG0183	Belongs to the thiolase family
CJO93_RS08835	COG1960	acyl-CoA dehydrogenase activity
CJO93_RS08840	COG1028	Short-chain dehydrogenase reductase Sdr
CJO93_RS08855	COG2130	NADP-dependent
CJO93_RS08875	COG0596	Alpha beta hydrolase
CJO93_RS08930	COG4974	Belongs to the 'phage' integrase family
CJO93_RS08980	COG0745	RESPONSE REGULATOR receiver
CJO93_RS08990	COG2801	Transposase and inactivated derivatives
CJO93_RS09020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CJO93_RS09040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CJO93_RS09045	COG1126	abc transporter atp-binding protein
CJO93_RS09050	COG0765	amino acid transport
CJO93_RS09055	COG0765	amino acid transport
CJO93_RS09060	COG4221	oxidoreductase activity
CJO93_RS09065	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CJO93_RS09075	COG1984	allophanate hydrolase subunit 2
CJO93_RS09080	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CJO93_RS09090	COG0511	ligase activity, forming carbon-carbon bonds
CJO93_RS09100	COG0436	Aminotransferase
CJO93_RS09105	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CJO93_RS09115	COG3265	gluconokinase activity
CJO93_RS09120	COG1028	Short-chain dehydrogenase reductase Sdr
CJO93_RS09125	COG1063	alcohol dehydrogenase
CJO93_RS09145	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CJO93_RS09180	COG0519	Catalyzes the synthesis of GMP from XMP
CJO93_RS09180	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CJO93_RS09195	COG0697	spore germination
CJO93_RS09205	COG2914	Belongs to the UPF0125 (RnfH) family
CJO93_RS09210	COG2867	negative regulation of translational initiation
CJO93_RS09215	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CJO93_RS09220	COG0330	HflC and HflK could
CJO93_RS09235	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CJO93_RS09240	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CJO93_RS09245	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CJO93_RS09250	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CJO93_RS09255	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CJO93_RS09260	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CJO93_RS09265	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CJO93_RS09285	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CJO93_RS09290	COG0575	Belongs to the CDS family
CJO93_RS09295	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CJO93_RS09300	COG0233	cytoplasmic translational termination
CJO93_RS09305	COG0528	UMP kinase activity
CJO93_RS09310	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CJO93_RS09315	COG0052	Belongs to the universal ribosomal protein uS2 family
CJO93_RS09320	COG0024	Methionine aminopeptidase
CJO93_RS09325	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CJO93_RS09330	COG1187	pseudouridine synthase activity
CJO93_RS09340	COG0242	peptide deformylase activity
CJO93_RS09345	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CJO93_RS09360	COG0596	Alpha beta hydrolase
CJO93_RS09375	COG2171	N-acyltransferase activity
CJO93_RS09385	COG1393	Belongs to the ArsC family
CJO93_RS09390	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CJO93_RS09400	COG2890	protein-(glutamine-N5) methyltransferase activity
CJO93_RS09405	COG0302	gtp cyclohydrolase
CJO93_RS09430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CJO93_RS09435	COG0601	transmembrane transport
CJO93_RS09440	COG0747	negative chemotaxis
CJO93_RS09445	COG4172	Belongs to the ABC transporter superfamily
CJO93_RS09460	COG0488	(ABC) transporter
CJO93_RS09470	COG1683	Conserved Protein
CJO93_RS09475	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CJO93_RS09485	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CJO93_RS09490	COG0477	Major facilitator Superfamily
CJO93_RS09495	COG1573	uracil-dna glycosylase
CJO93_RS09500	COG0456	acetyltransferase
CJO93_RS09505	COG1214	PFAM Peptidase M22, glycoprotease
CJO93_RS09515	COG2814	Major facilitator Superfamily
CJO93_RS09525	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CJO93_RS09540	COG0583	DNA-binding transcription factor activity
CJO93_RS09550	COG2224	Isocitrate lyase
CJO93_RS09570	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CJO93_RS09585	COG3275	phosphorelay sensor kinase activity
CJO93_RS09600	COG0583	DNA-binding transcription factor activity
CJO93_RS09605	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CJO93_RS09610	COG4208	sulfate ABC transporter
CJO93_RS09635	COG1116	anion transmembrane transporter activity
CJO93_RS09640	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CJO93_RS09645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CJO93_RS09650	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CJO93_RS09655	COG0431	NADPH-dependent FMN reductase
CJO93_RS09660	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CJO93_RS09665	COG2985	domain, Protein
CJO93_RS09670	COG0281	malic enzyme
CJO93_RS09685	COG4191	Histidine kinase
CJO93_RS09695	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CJO93_RS09705	COG0542	response to heat
CJO93_RS09715	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CJO93_RS09720	COG0314	molybdopterin synthase activity
CJO93_RS09725	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CJO93_RS09730	COG0303	'Molybdopterin
CJO93_RS09735	COG1573	uracil-dna glycosylase
CJO93_RS09750	COG0436	Aminotransferase
CJO93_RS09760	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CJO93_RS09765	COG2076	Multidrug Resistance protein
CJO93_RS09770	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CJO93_RS09785	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CJO93_RS09785	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CJO93_RS09800	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CJO93_RS09810	COG0791	NLP P60 protein
CJO93_RS09815	COG0306	phosphate transporter
CJO93_RS09825	COG0305	Participates in initiation and elongation during chromosome replication
CJO93_RS09830	COG0359	binds to the 23S rRNA
CJO93_RS09835	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CJO93_RS09845	COG0360	Binds together with S18 to 16S ribosomal RNA
CJO93_RS09860	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CJO93_RS09875	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CJO93_RS09900	COG1024	Enoyl-CoA hydratase
CJO93_RS09910	COG1217	gtp-binding protein TYPA
CJO93_RS09925	COG1566	PFAM secretion protein HlyD family protein
CJO93_RS09930	COG2814	Major facilitator Superfamily
CJO93_RS09935	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CJO93_RS09940	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CJO93_RS09945	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CJO93_RS09950	COG2251	uridine kinase activity
CJO93_RS09950	COG0195	Participates in both transcription termination and antitermination
CJO93_RS09955	COG0779	Required for maturation of 30S ribosomal subunits
CJO93_RS09960	COG1187	pseudouridine synthase activity
CJO93_RS09965	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CJO93_RS09975	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CJO93_RS10010	COG3278	Belongs to the heme-copper respiratory oxidase family
CJO93_RS10020	COG2217	Heavy metal translocating P-type atpase
CJO93_RS10030	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CJO93_RS10035	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CJO93_RS10040	COG0508	dehydrogenase complex catalyzes the overall conversion of
CJO93_RS10045	COG0567	Dehydrogenase, E1 component
CJO93_RS10050	COG0584	glycerophosphoryl diester phosphodiesterase
CJO93_RS10055	COG3842	ATPase activity
CJO93_RS10065	COG1175	transmembrane transport
CJO93_RS10070	COG1653	transport
CJO93_RS10085	COG2204	response regulator
CJO93_RS10100	COG0174	glutamine synthetase
CJO93_RS10110	COG1546	Belongs to the CinA family
CJO93_RS10110	COG1058	Belongs to the CinA family
CJO93_RS10135	COG1643	Atp-dependent helicase
CJO93_RS10140	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CJO93_RS10140	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CJO93_RS10145	COG1737	Transcriptional regulator
CJO93_RS10150	COG0673	inositol 2-dehydrogenase activity
CJO93_RS10160	COG0673	inositol 2-dehydrogenase activity
CJO93_RS10170	COG1082	Xylose isomerase domain protein TIM barrel
CJO93_RS10175	COG1172	Belongs to the binding-protein-dependent transport system permease family
CJO93_RS10180	COG1129	ABC transporter
CJO93_RS10190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CJO93_RS10195	COG3962	Belongs to the TPP enzyme family
CJO93_RS10205	COG3718	enzyme involved in inositol metabolism
CJO93_RS10215	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CJO93_RS10225	COG1953	Uracil, thiamine, allantoin
CJO93_RS10230	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CJO93_RS10235	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CJO93_RS10245	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CJO93_RS10250	COG0557	exoribonuclease II activity
CJO93_RS10260	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CJO93_RS10265	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CJO93_RS10270	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CJO93_RS10280	COG0330	HflC and HflK could
CJO93_RS10285	COG0330	HflC and HflK could
CJO93_RS10290	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CJO93_RS10295	COG1923	regulation of RNA biosynthetic process
CJO93_RS10300	COG1160	GTP binding
CJO93_RS10310	COG2976	Protein conserved in bacteria
CJO93_RS10315	COG0124	histidyl-tRNA synthetase
CJO93_RS10320	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CJO93_RS10335	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CJO93_RS10340	COG0105	UTP biosynthetic process
CJO93_RS10350	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CJO93_RS10370	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CJO93_RS10375	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CJO93_RS10380	COG1028	Short-chain dehydrogenase reductase Sdr
CJO93_RS10380	COG3321	synthase
CJO93_RS10380	COG0604	alcohol dehydrogenase
CJO93_RS10385	COG1902	pentaerythritol trinitrate reductase activity
CJO93_RS10390	COG1309	transcriptional regulator
CJO93_RS10395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CJO93_RS10405	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CJO93_RS10410	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CJO93_RS10425	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CJO93_RS10430	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CJO93_RS10435	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CJO93_RS10445	COG1074	ATP-dependent DNA helicase activity
CJO93_RS10460	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CJO93_RS10465	COG2204	response regulator
CJO93_RS10470	COG2197	response regulator
CJO93_RS10475	COG3228	Belongs to the MtfA family
CJO93_RS10485	COG0254	rRNA binding
CJO93_RS10495	COG0534	Mate efflux family protein
CJO93_RS10530	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CJO93_RS10535	COG1752	Esterase of the alpha-beta hydrolase superfamily
CJO93_RS10540	COG0791	NLP P60 protein
CJO93_RS10545	COG4172	Belongs to the ABC transporter superfamily
CJO93_RS10550	COG4239	(ABC) transporter, permease
CJO93_RS10555	COG4174	ABC transporter (Permease)
CJO93_RS10560	COG4166	transmembrane transport
CJO93_RS10575	COG0527	aspartate kinase activity
CJO93_RS10580	COG0037	tRNA processing
CJO93_RS10585	COG0825	malonyl-CoA metabolic process
CJO93_RS10590	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CJO93_RS10595	COG0215	cysteine-tRNA ligase activity
CJO93_RS10610	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CJO93_RS10615	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CJO93_RS10620	COG1045	serine acetyltransferase
CJO93_RS10630	COG0483	inositol monophosphate 1-phosphatase activity
CJO93_RS10635	COG1396	sequence-specific DNA binding
CJO93_RS10645	COG2258	MOSC domain
CJO93_RS10650	COG0840	transmembrane signaling receptor activity
CJO93_RS10655	COG0840	transmembrane signaling receptor activity
CJO93_RS10665	COG2814	Major facilitator Superfamily
CJO93_RS10670	COG0583	DNA-binding transcription factor activity
CJO93_RS10675	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CJO93_RS10690	COG2850	peptidyl-arginine hydroxylation
CJO93_RS10695	COG1234	tRNA 3'-trailer cleavage
CJO93_RS10700	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CJO93_RS10705	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CJO93_RS10715	COG0180	Tryptophanyl-tRNA synthetase
CJO93_RS10720	COG1994	Peptidase M50
CJO93_RS10725	COG0009	L-threonylcarbamoyladenylate synthase
CJO93_RS10730	COG0613	PHP domain protein
CJO93_RS10735	COG0492	ferredoxin-NADP+ reductase activity
CJO93_RS10750	COG3011	Protein conserved in bacteria
CJO93_RS10755	COG2267	carboxylic ester hydrolase activity
CJO93_RS10760	COG2833	Protein of unknown function (DUF455)
CJO93_RS10770	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CJO93_RS10780	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CJO93_RS10785	COG0148	phosphopyruvate hydratase activity
CJO93_RS10795	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CJO93_RS10800	COG0504	CTP synthase activity
CJO93_RS10805	COG2267	carboxylic ester hydrolase activity
CJO93_RS10825	COG2308	Evidence 4 Homologs of previously reported genes of
CJO93_RS10835	COG0084	hydrolase, TatD family'
CJO93_RS10840	COG1136	(ABC) transporter
CJO93_RS10855	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CJO93_RS10860	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CJO93_RS10885	COG2855	membrane
CJO93_RS10890	COG0583	DNA-binding transcription factor activity
CJO93_RS10970	COG0436	Aminotransferase
CJO93_RS10980	COG0583	DNA-binding transcription factor activity
CJO93_RS10985	COG2271	Major facilitator Superfamily
CJO93_RS11025	COG0625	glutathione transferase activity
CJO93_RS11030	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CJO93_RS11040	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CJO93_RS11050	COG2271	Major facilitator Superfamily
CJO93_RS11060	COG2186	Transcriptional regulator
CJO93_RS11065	COG3385	transposase activity
CJO93_RS11075	COG0745	RESPONSE REGULATOR receiver
CJO93_RS11085	COG5002	protein histidine kinase activity
CJO93_RS11095	COG0745	RESPONSE REGULATOR receiver
CJO93_RS11120	COG0322	excinuclease ABC activity
CJO93_RS11130	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CJO93_RS11140	COG0736	holo-[acyl-carrier-protein] synthase activity
CJO93_RS11145	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CJO93_RS11155	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CJO93_RS11160	COG0571	ribonuclease III activity
CJO93_RS11170	COG0681	Belongs to the peptidase S26 family
CJO93_RS11175	COG0481	GTPase activity
CJO93_RS11185	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CJO93_RS11210	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CJO93_RS11215	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CJO93_RS11220	COG1028	Short-chain dehydrogenase reductase Sdr
CJO93_RS11230	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CJO93_RS11235	COG0416	fatty acid biosynthetic process
CJO93_RS11240	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CJO93_RS11245	COG1399	metal-binding, possibly nucleic acid-binding protein
CJO93_RS11250	COG0424	maF-like protein
CJO93_RS11260	COG0616	signal peptide processing
CJO93_RS11260	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CJO93_RS11270	COG0546	phosphoglycolate phosphatase activity
CJO93_RS11280	COG1530	ribonuclease E activity
CJO93_RS11285	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CJO93_RS11290	COG0746	molybdenum cofactor guanylyltransferase activity
CJO93_RS11305	COG1322	Protein conserved in bacteria
CJO93_RS11310	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CJO93_RS11325	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CJO93_RS11335	COG1028	Short-chain dehydrogenase reductase Sdr
CJO93_RS11340	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CJO93_RS11350	COG3385	transposase activity
CJO93_RS11365	COG0443	Heat shock 70 kDa protein
CJO93_RS11370	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CJO93_RS11380	COG0316	Belongs to the HesB IscA family
CJO93_RS11385	COG0822	iron-sulfur transferase activity
CJO93_RS11390	COG1104	cysteine desulfurase activity
CJO93_RS11400	COG1879	ABC-type sugar transport system periplasmic component
CJO93_RS11410	COG1172	Belongs to the binding-protein-dependent transport system permease family
CJO93_RS11415	COG1609	Transcriptional regulator
CJO93_RS11420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CJO93_RS11430	COG0556	nucleotide-excision repair
CJO93_RS11445	COG1309	transcriptional regulator
CJO93_RS11450	COG2878	Part of a membrane complex involved in electron transport
CJO93_RS11455	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CJO93_RS11460	COG0778	Nitroreductase
CJO93_RS11495	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CJO93_RS11535	COG0326	Molecular chaperone. Has ATPase activity
CJO93_RS11540	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CJO93_RS11545	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CJO93_RS11550	COG0697	spore germination
CJO93_RS11560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CJO93_RS11565	COG0625	glutathione transferase activity
CJO93_RS11580	COG1620	l-lactate permease
CJO93_RS11600	COG0741	lytic transglycosylase activity
CJO93_RS11610	COG0488	(ABC) transporter
CJO93_RS11650	COG0513	Belongs to the DEAD box helicase family
CJO93_RS11655	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CJO93_RS11665	COG0861	Integral membrane protein TerC family
CJO93_RS11675	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CJO93_RS11685	COG0312	modulator of DNA gyrase
CJO93_RS11690	COG3028	Belongs to the UPF0307 family
CJO93_RS11695	COG0521	Mo-molybdopterin cofactor biosynthetic process
CJO93_RS11700	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CJO93_RS11705	COG0501	Belongs to the peptidase M48B family
CJO93_RS11710	COG1162	GTPase activity
CJO93_RS11720	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CJO93_RS11725	COG0494	nUDIX hydrolase
CJO93_RS11730	COG0335	large ribosomal subunit rRNA binding
CJO93_RS11735	COG0336	Belongs to the RNA methyltransferase TrmD family
CJO93_RS11740	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CJO93_RS11745	COG0228	four-way junction DNA binding
CJO93_RS11780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CJO93_RS11785	COG1960	acyl-CoA dehydrogenase activity
CJO93_RS11805	COG2011	ABC-type metal ion transport system permease component
CJO93_RS11810	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CJO93_RS11815	COG0123	including yeast histone deacetylase and acetoin utilization protein
CJO93_RS11820	COG2951	lytic endotransglycosylase activity
CJO93_RS11835	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CJO93_RS11840	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CJO93_RS11850	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CJO93_RS11860	COG0776	regulation of translation
CJO93_RS11870	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CJO93_RS11875	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CJO93_RS11880	COG0287	Prephenate dehydrogenase
CJO93_RS11885	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CJO93_RS11890	COG1605	Chorismate mutase
CJO93_RS11890	COG0077	Prephenate dehydratase
CJO93_RS11895	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CJO93_RS11920	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CJO93_RS12055	COG4221	oxidoreductase activity
CJO93_RS12065	COG2085	NADP oxidoreductase coenzyme F420-dependent
CJO93_RS12140	COG3039	Transposase
CJO93_RS12210	COG1309	transcriptional regulator
CJO93_RS12215	COG1028	Short-chain dehydrogenase reductase Sdr
CJO93_RS12220	COG0604	alcohol dehydrogenase
CJO93_RS12265	COG3039	Transposase
CJO93_RS12270	COG3039	Transposase
CJO93_RS12275	COG0778	Nitroreductase
CJO93_RS12290	COG4305	rare lipoprotein A
CJO93_RS12310	COG1280	lysine exporter protein (LysE YggA)
CJO93_RS12325	COG0425	Belongs to the sulfur carrier protein TusA family
CJO93_RS12340	COG1942	4-Oxalocrotonate Tautomerase
CJO93_RS12345	COG0235	Class ii aldolase
CJO93_RS12350	COG0477	Major facilitator Superfamily
CJO93_RS12365	COG0330	HflC and HflK could
CJO93_RS12390	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CJO93_RS12395	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CJO93_RS12420	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CJO93_RS12450	COG4681	YaeQ
CJO93_RS12465	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CJO93_RS12475	COG0318	PFAM AMP-dependent synthetase and ligase
CJO93_RS12480	COG3118	belongs to the thioredoxin family
CJO93_RS12490	COG2703	oxygen carrier activity
CJO93_RS12495	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CJO93_RS12500	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CJO93_RS12505	COG2982	Protein involved in outer membrane biogenesis
CJO93_RS12530	COG0259	pyridoxamine-phosphate oxidase activity
CJO93_RS12535	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CJO93_RS12545	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CJO93_RS12550	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CJO93_RS12560	COG1522	sequence-specific DNA binding
CJO93_RS12565	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CJO93_RS12575	COG3483	tryptophan 2,3-dioxygenase activity
CJO93_RS12585	COG1960	acyl-CoA dehydrogenase activity
CJO93_RS12590	COG2252	PERMEase
CJO93_RS12595	COG0450	alkyl hydroperoxide reductase
CJO93_RS12600	COG4575	ribosome binding
CJO93_RS12620	COG1136	(ABC) transporter
CJO93_RS12625	COG0390	transport system, permease component
CJO93_RS12650	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CJO93_RS12655	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CJO93_RS12660	COG0745	RESPONSE REGULATOR receiver
CJO93_RS12670	COG3385	transposase activity
CJO93_RS12685	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CJO93_RS12700	COG0823	Involved in the tonB-independent uptake of proteins
CJO93_RS12720	COG0824	Thioesterase
CJO93_RS12725	COG4221	oxidoreductase activity
CJO93_RS12730	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CJO93_RS12735	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CJO93_RS12800	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CJO93_RS12800	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CJO93_RS12815	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CJO93_RS12820	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CJO93_RS12825	COG0436	Aminotransferase
CJO93_RS12835	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CJO93_RS12865	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CJO93_RS12870	COG1902	pentaerythritol trinitrate reductase activity
CJO93_RS12875	COG1968	undecaprenyl-diphosphatase activity
CJO93_RS12900	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CJO93_RS12905	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CJO93_RS12905	COG0425	Belongs to the sulfur carrier protein TusA family
CJO93_RS12925	COG0859	PFAM glycosyl transferase family 9
CJO93_RS12940	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CJO93_RS12975	COG1088	dTDP-glucose 4,6-dehydratase activity
CJO93_RS12980	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CJO93_RS12995	COG0540	Belongs to the ATCase OTCase family
CJO93_RS13000	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CJO93_RS13005	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CJO93_RS13010	COG1678	Uncharacterized ACR, COG1678
CJO93_RS13015	COG1187	pseudouridine synthase activity
CJO93_RS13025	COG0784	Response regulator, receiver
CJO93_RS13025	COG2198	Histidine kinase
CJO93_RS13025	COG0643	Histidine kinase
CJO93_RS13030	COG0840	transmembrane signaling receptor activity
CJO93_RS13050	COG1773	rubredoxin
CJO93_RS13055	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CJO93_RS13060	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CJO93_RS13070	COG1704	LemA family
CJO93_RS13115	COG4964	Belongs to the GSP D family
CJO93_RS13175	COG4269	membrane
CJO93_RS13180	COG0459	protein refolding
CJO93_RS13185	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CJO93_RS13205	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CJO93_RS13210	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
CJO93_RS13215	COG2974	May be involved in recombination
CJO93_RS13240	COG0697	spore germination
CJO93_RS13280	COG0840	transmembrane signaling receptor activity
CJO93_RS13285	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CJO93_RS13305	COG2995	paraquat-inducible protein a
CJO93_RS13310	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CJO93_RS13310	COG3008	intermembrane lipid transfer
CJO93_RS13320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CJO93_RS13385	COG0738	Major facilitator superfamily
CJO93_RS13390	COG2027	D-alanyl-D-alanine carboxypeptidase
CJO93_RS13395	COG1763	Mo-molybdopterin cofactor biosynthetic process
CJO93_RS13415	COG0546	phosphoglycolate phosphatase activity
CJO93_RS13425	COG0009	L-threonylcarbamoyladenylate synthase
CJO93_RS13430	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CJO93_RS13435	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CJO93_RS13440	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CJO93_RS13450	COG0469	pyruvate kinase activity
CJO93_RS13455	COG0126	phosphoglycerate kinase activity
CJO93_RS13485	COG0859	PFAM glycosyl transferase family 9
CJO93_RS13495	COG0429	hydrolase of the alpha beta-hydrolase fold
CJO93_RS13505	COG4783	chaperone-mediated protein folding
CJO93_RS13510	COG0315	cyclic pyranopterin monophosphate synthase activity
CJO93_RS13520	COG4969	Belongs to the N-Me-Phe pilin family
CJO93_RS13525	COG4969	Belongs to the N-Me-Phe pilin family
CJO93_RS13530	COG0861	Integral membrane protein TerC family
CJO93_RS13540	COG0045	succinate-CoA ligase (ADP-forming) activity
CJO93_RS13550	COG2137	regulation of response to DNA damage stimulus
CJO93_RS13555	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CJO93_RS13575	COG0477	Major facilitator Superfamily
CJO93_RS13620	COG0513	Belongs to the DEAD box helicase family
CJO93_RS13645	COG0318	PFAM AMP-dependent synthetase and ligase
CJO93_RS13655	COG3039	Transposase
CJO93_RS13675	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CJO93_RS13680	COG1702	phosphate starvation-inducible protein PhoH
CJO93_RS13685	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CJO93_RS13690	COG4535	Mg2 and Co2 transporter CorC
CJO93_RS13695	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CJO93_RS13700	COG0752	glycyl-tRNA synthetase alpha subunit
CJO93_RS13710	COG0751	glycine-tRNA ligase activity
CJO93_RS13715	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CJO93_RS13720	COG0204	Acyl-transferase
CJO93_RS13730	COG0346	lactoylglutathione lyase activity
CJO93_RS13735	COG0697	spore germination
CJO93_RS13740	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CJO93_RS13745	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CJO93_RS13750	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CJO93_RS13755	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CJO93_RS13775	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CJO93_RS13785	COG0006	proline dipeptidase activity
CJO93_RS13790	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CJO93_RS13800	COG4680	protein conserved in bacteria
CJO93_RS13815	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CJO93_RS13820	COG0138	bifunctional purine biosynthesis protein purh
CJO93_RS13825	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CJO93_RS13835	COG0632	four-way junction helicase activity
CJO93_RS13840	COG2255	four-way junction helicase activity
CJO93_RS13855	COG1490	D-aminoacyl-tRNA deacylase activity
CJO93_RS13860	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CJO93_RS13865	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CJO93_RS13870	COG0316	Belongs to the HesB IscA family
CJO93_RS13885	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CJO93_RS13890	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CJO93_RS13910	COG0418	dihydroorotase activity
CJO93_RS13920	COG0473	3-isopropylmalate dehydrogenase activity
CJO93_RS13925	COG0121	glutamine amidotransferase
CJO93_RS13930	COG1126	abc transporter atp-binding protein
CJO93_RS13935	COG0765	amino acid transport
CJO93_RS13940	COG0765	amino acid transport
CJO93_RS13950	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CJO93_RS13960	COG5265	(ABC) transporter
CJO93_RS13970	COG1024	Enoyl-CoA hydratase
CJO93_RS13975	COG0183	Belongs to the thiolase family
CJO93_RS13980	COG1250	3-hydroxyacyl-CoA dehydrogenase
CJO93_RS13980	COG1024	Enoyl-CoA hydratase
CJO93_RS13985	COG1960	acyl-CoA dehydrogenase activity
CJO93_RS14000	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CJO93_RS14005	COG3568	Endonuclease Exonuclease Phosphatase
CJO93_RS14010	COG0494	nUDIX hydrolase
CJO93_RS14020	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CJO93_RS14045	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CJO93_RS14060	COG2226	methyltransferase
CJO93_RS14070	COG4178	(ABC) transporter
CJO93_RS14085	COG1238	metal cluster binding
CJO93_RS14090	COG0700	Nucleoside recognition
CJO93_RS14105	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CJO93_RS14110	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CJO93_RS14110	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CJO93_RS14140	COG0318	PFAM AMP-dependent synthetase and ligase
CJO93_RS14145	COG3265	gluconokinase activity
CJO93_RS14160	COG2391	methyltransferase activity
CJO93_RS14175	COG1028	Short-chain dehydrogenase reductase Sdr
CJO93_RS14190	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CJO93_RS14215	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CJO93_RS14255	COG0629	single-stranded DNA binding
CJO93_RS14260	COG2814	Major facilitator Superfamily
CJO93_RS14275	COG1280	lysine exporter protein (LysE YggA)
CJO93_RS14280	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CJO93_RS14285	COG0693	protein deglycase activity
CJO93_RS14310	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CJO93_RS14325	COG1137	ATPase activity
CJO93_RS14330	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CJO93_RS14335	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CJO93_RS14345	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CJO93_RS14355	COG1660	Displays ATPase and GTPase activities
CJO93_RS14365	COG1194	a g-specific adenine glycosylase
CJO93_RS14375	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CJO93_RS14385	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CJO93_RS14390	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CJO93_RS14400	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CJO93_RS14405	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CJO93_RS14410	COG0193	aminoacyl-tRNA hydrolase activity
CJO93_RS14425	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CJO93_RS14430	COG0742	ribosomal rna small subunit methyltransferase
CJO93_RS14435	COG0612	Peptidase, M16
CJO93_RS14440	COG0612	Peptidase, M16
CJO93_RS14455	COG0625	glutathione transferase activity
CJO93_RS14465	COG3707	response regulator
CJO93_RS14475	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CJO93_RS14480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CJO93_RS14485	COG1116	anion transmembrane transporter activity
CJO93_RS14490	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CJO93_RS14495	COG1741	Belongs to the pirin family
CJO93_RS14510	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CJO93_RS14515	COG1999	signal sequence binding
CJO93_RS14520	COG0109	protoheme IX farnesyltransferase activity
CJO93_RS14525	COG1612	heme a metabolic process
CJO93_RS14555	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
CJO93_RS14560	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CJO93_RS14575	COG2226	methyltransferase
CJO93_RS14580	COG1040	competence protein
CJO93_RS14590	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CJO93_RS14595	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CJO93_RS14600	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CJO93_RS14605	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CJO93_RS14610	COG0588	phosphoglycerate mutase activity
CJO93_RS14615	COG0793	Belongs to the peptidase S41A family
CJO93_RS14635	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CJO93_RS14640	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CJO93_RS14650	COG0189	ligase activity
CJO93_RS14660	COG0004	ammonium transporteR
CJO93_RS14700	COG3039	Transposase
CJO93_RS14840	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CJO93_RS14850	COG2204	response regulator
CJO93_RS14855	COG4191	Histidine kinase
CJO93_RS14860	COG1301	dicarboxylic acid transport
CJO93_RS14865	COG3411	Ferredoxin
CJO93_RS14875	COG1686	Belongs to the peptidase S11 family
CJO93_RS14880	COG2921	Belongs to the UPF0250 family
CJO93_RS14885	COG0583	DNA-binding transcription factor activity
CJO93_RS14895	COG0321	lipoyl(octanoyl) transferase activity
CJO93_RS14900	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CJO93_RS14945	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CJO93_RS14950	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CJO93_RS14950	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CJO93_RS14955	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CJO93_RS14965	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CJO93_RS14990	COG1024	Enoyl-CoA hydratase
CJO93_RS15020	COG2267	carboxylic ester hydrolase activity
CJO93_RS15040	COG1410	methionine synthase
CJO93_RS15040	COG0646	methionine synthase
CJO93_RS15050	COG2197	response regulator
CJO93_RS15075	COG0018	arginyl-trna synthetase
CJO93_RS15085	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CJO93_RS15090	COG4221	oxidoreductase activity
CJO93_RS15100	COG3039	Transposase
CJO93_RS15135	COG2329	Antibiotic biosynthesis monooxygenase
CJO93_RS15145	COG0789	Transcriptional regulator
CJO93_RS15150	COG1960	acyl-CoA dehydrogenase activity
CJO93_RS15155	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
CJO93_RS15160	COG0288	reversible hydration of carbon dioxide
CJO93_RS15165	COG0183	Belongs to the thiolase family
CJO93_RS15170	COG1028	Short-chain dehydrogenase reductase Sdr
CJO93_RS15175	COG1960	acyl-CoA dehydrogenase activity
CJO93_RS15190	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CJO93_RS15195	COG3012	SEC-C Motif Domain Protein
CJO93_RS15200	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CJO93_RS15210	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CJO93_RS15215	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CJO93_RS15225	COG4770	biotin carboxylase activity
CJO93_RS15240	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CJO93_RS15270	COG0596	Alpha beta hydrolase
CJO93_RS15310	COG1250	3-hydroxyacyl-CoA dehydrogenase
CJO93_RS15315	COG0583	DNA-binding transcription factor activity
CJO93_RS15350	COG1703	isobutyryl-CoA mutase activity
CJO93_RS15350	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CJO93_RS15350	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CJO93_RS15405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CJO93_RS15415	COG0430	RNA-3'-phosphate cyclase activity
CJO93_RS15420	COG3541	Predicted nucleotidyltransferase
CJO93_RS15425	COG1690	Belongs to the RtcB family
CJO93_RS15435	COG4650	regulator
CJO93_RS15450	COG1254	Belongs to the acylphosphatase family
CJO93_RS15465	COG2814	Major facilitator Superfamily
CJO93_RS15470	COG1028	Short-chain dehydrogenase reductase Sdr
CJO93_RS15475	COG0583	DNA-binding transcription factor activity
CJO93_RS15480	COG0519	Catalyzes the synthesis of GMP from XMP
CJO93_RS15480	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CJO93_RS15495	COG1733	regulation of RNA biosynthetic process
CJO93_RS15550	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CJO93_RS15555	COG0071	Belongs to the small heat shock protein (HSP20) family
CJO93_RS15570	COG3038	cytochrome b561
CJO93_RS15590	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CJO93_RS15605	COG2197	response regulator
CJO93_RS15610	COG3851	Histidine kinase
CJO93_RS15615	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CJO93_RS15645	COG0589	response to stress
CJO93_RS15650	COG3039	Transposase
CJO93_RS15655	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CJO93_RS15675	COG0589	response to stress
CJO93_RS15685	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CJO93_RS15690	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CJO93_RS15700	COG0037	tRNA processing
CJO93_RS15705	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CJO93_RS15710	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CJO93_RS15710	COG0546	phosphoglycolate phosphatase activity
CJO93_RS15735	COG0493	'glutamate synthase
CJO93_RS15750	COG0842	Transport permease protein
CJO93_RS15755	COG1131	(ABC) transporter
CJO93_RS15770	COG1012	belongs to the aldehyde dehydrogenase family
CJO93_RS15775	COG0583	DNA-binding transcription factor activity
CJO93_RS15780	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CJO93_RS15805	COG2223	nitrite transmembrane transporter activity
CJO93_RS15820	COG0697	spore germination
CJO93_RS15845	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CJO93_RS15865	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CJO93_RS15870	COG4682	membrane
CJO93_RS15875	COG0708	Exodeoxyribonuclease III
CJO93_RS15880	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CJO93_RS15885	COG2326	polyphosphate kinase activity
CJO93_RS15890	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CJO93_RS15895	COG1560	Kdo2-lipid A biosynthetic process
CJO93_RS15905	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CJO93_RS15925	COG0517	IMP dehydrogenase activity
CJO93_RS15935	COG1522	sequence-specific DNA binding
CJO93_RS15980	COG1960	acyl-CoA dehydrogenase activity
CJO93_RS16015	COG2070	2-Nitropropane dioxygenase
CJO93_RS16020	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CJO93_RS16035	COG2022	thiamine diphosphate biosynthetic process
CJO93_RS16045	COG2764	glyoxalase bleomycin resistance protein dioxygenase
CJO93_RS16070	COG0351	phosphomethylpyrimidine kinase
CJO93_RS16080	COG1785	Belongs to the alkaline phosphatase family
CJO93_RS16085	COG1785	Belongs to the alkaline phosphatase family
CJO93_RS16100	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CJO93_RS16105	COG1950	PFAM Membrane protein of
CJO93_RS16110	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CJO93_RS16120	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CJO93_RS16140	COG0617	tRNA 3'-terminal CCA addition
CJO93_RS16145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CJO93_RS16150	COG3246	L-lysine catabolic process to acetate
CJO93_RS16155	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CJO93_RS16185	COG5000	phosphorelay sensor kinase activity
CJO93_RS16200	COG0501	Belongs to the peptidase M48B family
CJO93_RS16210	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CJO93_RS16220	COG0242	peptide deformylase activity
CJO93_RS16225	COG1652	LysM domain
CJO93_RS16230	COG0758	DNA mediated transformation
CJO93_RS16245	COG0583	DNA-binding transcription factor activity
CJO93_RS16250	COG0318	PFAM AMP-dependent synthetase and ligase
CJO93_RS16255	COG0772	Belongs to the SEDS family
CJO93_RS16260	COG0768	penicillin binding
CJO93_RS16270	COG1792	Involved in formation and maintenance of cell shape
CJO93_RS16275	COG1077	Cell shape determining protein MreB Mrl
CJO93_RS16280	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CJO93_RS16285	COG0154	amidase activity
CJO93_RS16300	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CJO93_RS16310	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CJO93_RS16315	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CJO93_RS16335	COG0523	cobalamin synthesis protein
CJO93_RS16350	COG0747	negative chemotaxis
CJO93_RS16355	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CJO93_RS16360	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CJO93_RS16370	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CJO93_RS16400	COG1595	DNA-templated transcription, initiation
CJO93_RS16405	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CJO93_RS16420	COG3385	transposase activity
CJO93_RS16430	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CJO93_RS16440	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CJO93_RS16450	COG3385	transposase activity
CJO93_RS16465	COG2879	small protein
CJO93_RS16470	COG1966	Carbon starvation protein
CJO93_RS16485	COG3622	Belongs to the hyi family
CJO93_RS16495	COG0745	RESPONSE REGULATOR receiver
CJO93_RS16500	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CJO93_RS16510	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CJO93_RS16515	COG3384	dioxygenase
CJO93_RS16530	COG1309	transcriptional regulator
CJO93_RS16535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CJO93_RS16540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CJO93_RS16550	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CJO93_RS16565	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CJO93_RS16570	COG0706	membrane insertase activity
CJO93_RS16575	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CJO93_RS16580	COG0594	ribonuclease P activity
CJO93_RS16585	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CJO93_RS16595	COG1278	Cold shock
CJO93_RS16620	COG0477	Major facilitator Superfamily
CJO93_RS16625	COG4191	Histidine kinase
CJO93_RS16635	COG4377	Putative membrane peptidase family (DUF2324)
CJO93_RS16670	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CJO93_RS16715	COG3039	Transposase
CJO93_RS16730	COG1607	acyl-coa hydrolase
CJO93_RS16760	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CJO93_RS16770	COG0534	Mate efflux family protein
CJO93_RS16775	COG3251	PFAM MbtH domain protein
CJO93_RS16785	COG0529	Catalyzes the synthesis of activated sulfate
CJO93_RS16820	COG3039	Transposase
CJO93_RS16850	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CJO93_RS16865	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CJO93_RS16885	COG0318	PFAM AMP-dependent synthetase and ligase
CJO93_RS16900	COG0028	Belongs to the TPP enzyme family
CJO93_RS16945	COG1846	Transcriptional regulator
CJO93_RS16950	COG1024	Enoyl-CoA hydratase
CJO93_RS16955	COG1012	belongs to the aldehyde dehydrogenase family
CJO93_RS16985	COG0657	acetylesterase activity
CJO93_RS16995	COG2814	Major facilitator Superfamily
CJO93_RS17005	COG1640	4-alpha-glucanotransferase
CJO93_RS17010	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CJO93_RS17025	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CJO93_RS17030	COG0366	Alpha amylase catalytic
CJO93_RS17035	COG0366	Alpha amylase catalytic
CJO93_RS17040	COG0297	glycogen (starch) synthase activity
CJO93_RS17045	COG3720	iron ion transport
CJO93_RS17050	COG4771	TonB-dependent receptor
CJO93_RS17060	COG3634	alkyl hydroperoxide reductase activity
CJO93_RS17065	COG0735	belongs to the Fur family
CJO93_RS17085	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CJO93_RS17085	COG1918	ferrous iron import across plasma membrane
CJO93_RS17105	COG0840	transmembrane signaling receptor activity
CJO93_RS17125	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CJO93_RS17140	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CJO93_RS17150	COG0454	-acetyltransferase
CJO93_RS17150	COG0456	acetyltransferase
CJO93_RS17190	COG3039	Transposase
CJO93_RS17220	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
CJO93_RS17235	COG3706	GGDEF domain
CJO93_RS17240	COG0531	amino acid
CJO93_RS17245	COG0534	Mate efflux family protein
CJO93_RS17260	COG2197	response regulator
CJO93_RS17270	COG0726	polysaccharide deacetylase
CJO93_RS17270	COG1649	PFAM Uncharacterised BCR, COG1649
CJO93_RS17275	COG1215	transferase activity, transferring glycosyl groups
CJO93_RS17290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CJO93_RS17295	COG2274	protein secretion by the type I secretion system
CJO93_RS17330	COG0840	transmembrane signaling receptor activity
CJO93_RS17340	COG1028	Short-chain dehydrogenase reductase Sdr
CJO93_RS17350	COG2070	2-Nitropropane dioxygenase
CJO93_RS17355	COG0583	DNA-binding transcription factor activity
CJO93_RS17360	COG1695	Transcriptional regulator
CJO93_RS17375	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CJO93_RS17380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CJO93_RS17385	COG0745	RESPONSE REGULATOR receiver
CJO93_RS17390	COG2205	protein histidine kinase activity
CJO93_RS17405	COG0589	response to stress
CJO93_RS17440	COG0789	Transcriptional regulator
CJO93_RS17450	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CJO93_RS17475	COG1764	response to oxidative stress
CJO93_RS17490	COG0473	3-isopropylmalate dehydrogenase activity
CJO93_RS17525	COG2916	Histone family protein nucleoid-structuring protein H-NS
CJO93_RS17530	COG2188	Transcriptional regulator
CJO93_RS17535	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CJO93_RS17550	COG3039	Transposase
CJO93_RS17575	COG1815	bacterial-type flagellum-dependent cell motility
CJO93_RS17585	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CJO93_RS17590	COG1749	Flagellar hook protein flgE
CJO93_RS17595	COG4787	bacterial-type flagellum-dependent cell motility
CJO93_RS17605	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CJO93_RS17610	COG1706	bacterial-type flagellum-dependent cell motility
CJO93_RS17620	COG1256	bacterial-type flagellum assembly
CJO93_RS17640	COG2226	methyltransferase
CJO93_RS17655	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CJO93_RS17660	COG1028	Short-chain dehydrogenase reductase Sdr
CJO93_RS17670	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CJO93_RS17690	COG2986	histidine ammonia-lyase
CJO93_RS17700	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CJO93_RS17710	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CJO93_RS17720	COG0204	Acyl-transferase
CJO93_RS17735	COG1987	bacterial-type flagellum assembly
CJO93_RS17740	COG1338	Plays a role in the flagellum-specific transport system
CJO93_RS17770	COG2197	response regulator
CJO93_RS17800	COG1846	Transcriptional regulator
CJO93_RS17815	COG1677	Flagellar hook-basal body complex protein FliE
CJO93_RS17825	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CJO93_RS17860	COG2203	Gaf domain
CJO93_RS17860	COG3706	GGDEF domain
CJO93_RS17860	COG5001	Diguanylate cyclase
CJO93_RS17860	COG4251	negative regulation of phosphorylation
CJO93_RS17870	COG2203	Gaf domain
CJO93_RS17870	COG5001	Diguanylate cyclase
CJO93_RS17870	COG4251	negative regulation of phosphorylation
CJO93_RS17870	COG3706	GGDEF domain
CJO93_RS17890	COG3385	transposase activity
CJO93_RS17910	COG0318	PFAM AMP-dependent synthetase and ligase
CJO93_RS17970	COG4774	siderophore transport
CJO93_RS17985	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CJO93_RS17990	COG2423	ornithine cyclodeaminase activity
CJO93_RS17995	COG4264	IucA IucC family
CJO93_RS18000	COG2814	Major facilitator Superfamily
CJO93_RS18005	COG4264	IucA IucC family
CJO93_RS18010	COG4264	IucA IucC family
CJO93_RS18020	COG0019	diaminopimelate decarboxylase activity
CJO93_RS18100	COG0583	DNA-binding transcription factor activity
CJO93_RS18105	COG1126	abc transporter atp-binding protein
CJO93_RS18110	COG0765	amino acid transport
CJO93_RS18115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CJO93_RS18120	COG1522	sequence-specific DNA binding
CJO93_RS18125	COG2423	ornithine cyclodeaminase activity
CJO93_RS18150	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CJO93_RS18185	COG0537	adenosine 5'-monophosphoramidase activity
CJO93_RS18190	COG0786	glutamate:sodium symporter activity
CJO93_RS18240	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CJO93_RS18250	COG0840	transmembrane signaling receptor activity
CJO93_RS18265	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CJO93_RS18285	COG0668	transmembrane transport
CJO93_RS18325	COG3039	Transposase
CJO93_RS18345	COG3039	Transposase
CJO93_RS18350	COG5297	Belongs to the glycosyl hydrolase family 6
CJO93_RS18380	COG0300	oxidoreductase activity
CJO93_RS18420	COG3706	GGDEF domain
CJO93_RS18425	COG1914	H( )-stimulated, divalent metal cation uptake system
CJO93_RS18430	COG0443	Heat shock 70 kDa protein
CJO93_RS18450	COG2910	NAD(P)H-binding
CJO93_RS18495	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CJO93_RS18535	COG3039	Transposase
CJO93_RS18540	COG3039	Transposase
CJO93_RS18545	COG3039	Transposase
CJO93_RS18560	COG0402	S-adenosylhomocysteine deaminase activity
CJO93_RS18605	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CJO93_RS18695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CJO93_RS18710	COG0835	chemotaxis
CJO93_RS18710	COG0784	Response regulator, receiver
CJO93_RS18735	COG1404	Belongs to the peptidase S8 family
CJO93_RS18745	COG3396	Phenylacetate-CoA oxygenase
CJO93_RS18750	COG3460	Phenylacetate-CoA oxygenase
CJO93_RS18755	COG3396	Phenylacetate-CoA oxygenase
CJO93_RS18760	COG2151	metal-sulfur cluster biosynthetic enzyme
CJO93_RS18765	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CJO93_RS18795	COG0778	Nitroreductase
CJO93_RS18800	COG1797	cobyrinic acid a,c-diamide synthase activity
CJO93_RS18835	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
CJO93_RS18840	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
CJO93_RS18845	COG1648	precorrin-2 dehydrogenase activity
CJO93_RS18845	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CJO93_RS18865	COG3411	Ferredoxin
CJO93_RS18870	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CJO93_RS18890	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CJO93_RS18895	COG4941	Belongs to the sigma-70 factor family
CJO93_RS18910	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CJO93_RS18915	COG3251	PFAM MbtH domain protein
CJO93_RS18970	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CJO93_RS18975	COG1024	Enoyl-CoA hydratase
CJO93_RS18980	COG1024	Enoyl-CoA hydratase
CJO93_RS18995	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CJO93_RS19000	COG1960	acyl-CoA dehydrogenase activity
CJO93_RS19010	COG5002	protein histidine kinase activity
CJO93_RS19015	COG0745	RESPONSE REGULATOR receiver
CJO93_RS19040	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CJO93_RS19055	COG1846	Transcriptional regulator
CJO93_RS19070	COG1335	isochorismatase
CJO93_RS19080	COG2814	Major facilitator Superfamily
CJO93_RS19095	COG2818	Glycosylase
CJO93_RS19100	COG2807	transmembrane transport
CJO93_RS19125	COG1024	Enoyl-CoA hydratase
CJO93_RS19150	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CJO93_RS19155	COG0583	DNA-binding transcription factor activity
CJO93_RS19160	COG0259	pyridoxamine-phosphate oxidase activity
CJO93_RS19165	COG0019	diaminopimelate decarboxylase activity
CJO93_RS19170	COG0134	indole-3-glycerol-phosphate synthase activity
CJO93_RS19205	COG1960	acyl-CoA dehydrogenase activity
CJO93_RS19225	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CJO93_RS19240	COG3483	tryptophan 2,3-dioxygenase activity
CJO93_RS19250	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CJO93_RS19265	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CJO93_RS19270	COG1690	Belongs to the RtcB family
CJO93_RS19355	COG1858	cytochrome C peroxidase
CJO93_RS19360	COG1730	sister chromatid segregation
CJO93_RS19385	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
CJO93_RS19410	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CJO93_RS19540	COG3039	Transposase
CJO93_RS19560	COG1649	PFAM Uncharacterised BCR, COG1649
CJO93_RS19660	COG2197	response regulator
CJO93_RS19665	COG3916	Acyl-homoserine-lactone synthase
CJO93_RS19680	COG0525	valine-tRNA ligase activity
CJO93_RS19705	COG0318	PFAM AMP-dependent synthetase and ligase
CJO93_RS19710	COG2192	nodulation
CJO93_RS19715	COG3039	Transposase
CJO93_RS19730	COG3321	synthase
CJO93_RS19730	COG1028	Short-chain dehydrogenase reductase Sdr
CJO93_RS19730	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CJO93_RS19730	COG0300	oxidoreductase activity
CJO93_RS19730	COG0318	PFAM AMP-dependent synthetase and ligase
CJO93_RS19745	COG0436	Aminotransferase
CJO93_RS19780	COG0587	DNA-directed DNA polymerase activity
CJO93_RS19785	COG3620	sequence-specific DNA binding
CJO93_RS19790	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CJO93_RS19800	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CJO93_RS19815	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CJO93_RS19830	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CJO93_RS19850	COG0579	oxidoreductase
CJO93_RS19860	COG1309	transcriptional regulator
CJO93_RS19870	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CJO93_RS19895	COG0583	DNA-binding transcription factor activity
CJO93_RS19905	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CJO93_RS19910	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CJO93_RS19920	COG2271	Major facilitator Superfamily
CJO93_RS19930	COG2721	sulfolactate sulfo-lyase activity
CJO93_RS19935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CJO93_RS19950	COG2271	Major facilitator Superfamily
CJO93_RS19955	COG1056	cytidyltransferase-related domain
CJO93_RS19955	COG1051	belongs to the nudix hydrolase family
CJO93_RS19980	COG0840	transmembrane signaling receptor activity
CJO93_RS20030	COG1595	DNA-templated transcription, initiation
CJO93_RS20040	COG2197	response regulator
CJO93_RS20045	COG0745	RESPONSE REGULATOR receiver
CJO93_RS20085	COG4790	Type iii secretion
CJO93_RS20100	COG4789	Type iii secretion
CJO93_RS20105	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CJO93_RS20150	COG2207	Transcriptional regulator
CJO93_RS20155	COG1450	Type ii and iii secretion system protein
CJO93_RS20160	COG4886	Leucine-rich repeat (LRR) protein
CJO93_RS20185	COG5434	Belongs to the glycosyl hydrolase 28 family
CJO93_RS20205	COG1674	ftsk spoiiie
CJO93_RS20225	COG4974	Belongs to the 'phage' integrase family
CJO93_RS20275	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CJO93_RS20350	COG0179	Fumarylacetoacetate (FAA) hydrolase
CJO93_RS20410	COG3433	isochorismatase activity
CJO93_RS20410	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CJO93_RS20410	COG2226	methyltransferase
CJO93_RS20425	COG2375	cellular response to nickel ion
CJO93_RS20425	COG1132	(ABC) transporter
CJO93_RS20430	COG4771	TonB-dependent receptor
CJO93_RS20435	COG2226	methyltransferase
CJO93_RS20435	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CJO93_RS20435	COG3433	isochorismatase activity
CJO93_RS20445	COG2226	methyltransferase
CJO93_RS20450	COG0038	chloride channel
CJO93_RS20495	COG3023	N-Acetylmuramoyl-L-alanine amidase
CJO93_RS20500	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CJO93_RS20505	COG3842	ATPase activity
CJO93_RS20510	COG4208	sulfate ABC transporter
CJO93_RS20520	COG1840	ABC-type Fe3 transport system, periplasmic component
CJO93_RS20525	COG1609	Transcriptional regulator
CJO93_RS20540	COG0084	hydrolase, TatD family'
CJO93_RS20550	COG0470	DNA polymerase III
CJO93_RS20555	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CJO93_RS20560	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CJO93_RS20580	COG2831	hemolysin activation secretion protein
CJO93_RS20615	COG4974	Belongs to the 'phage' integrase family
CJO93_RS20800	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CJO93_RS20805	COG0156	8-amino-7-oxononanoate synthase activity
CJO93_RS20840	COG3045	CreA protein
CJO93_RS20875	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CJO93_RS20895	COG0840	transmembrane signaling receptor activity
CJO93_RS20905	COG3387	PFAM Glycoside hydrolase 15-related
CJO93_RS20930	COG0488	(ABC) transporter
CJO93_RS20935	COG1619	proteins homologs of microcin C7 resistance protein MccF
CJO93_RS20945	COG0720	synthase
CJO93_RS20950	COG0602	queuosine metabolic process
CJO93_RS20970	COG3550	peptidyl-serine autophosphorylation
CJO93_RS20990	COG3485	protocatechuate 3,4-dioxygenase
CJO93_RS20995	COG3485	protocatechuate 3,4-dioxygenase
CJO93_RS21000	COG0583	DNA-binding transcription factor activity
CJO93_RS21055	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
CJO93_RS21060	COG3604	Transcriptional regulator
CJO93_RS21065	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CJO93_RS21075	COG1396	sequence-specific DNA binding
CJO93_RS21105	COG3154	lipid carrier protein
CJO93_RS21115	COG0826	peptidase U32
CJO93_RS21120	COG0826	peptidase U32
CJO93_RS21135	COG2223	nitrite transmembrane transporter activity
CJO93_RS21140	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CJO93_RS21145	COG1140	nitrate reductase beta subunit
CJO93_RS21150	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CJO93_RS21155	COG2181	nitrate reductase activity
CJO93_RS21160	COG1763	Mo-molybdopterin cofactor biosynthetic process
CJO93_RS21165	COG3850	Histidine kinase
CJO93_RS21170	COG2197	response regulator
CJO93_RS21190	COG0352	thiamine-phosphate diphosphorylase activity
CJO93_RS21195	COG0477	Major facilitator Superfamily
CJO93_RS21200	COG1454	alcohol dehydrogenase
CJO93_RS21210	COG3039	Transposase
CJO93_RS21220	COG1999	signal sequence binding
CJO93_RS21240	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CJO93_RS21245	COG1301	dicarboxylic acid transport
CJO93_RS21290	COG3039	Transposase
CJO93_RS21305	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CJO93_RS21315	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CJO93_RS21335	COG0110	maltose O-acetyltransferase activity
CJO93_RS21350	COG2244	polysaccharide biosynthetic process
CJO93_RS21355	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CJO93_RS21360	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CJO93_RS21365	COG0489	protein tyrosine kinase activity
CJO93_RS21365	COG3206	protein involved in exopolysaccharide biosynthesis
CJO93_RS21370	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CJO93_RS21375	COG1596	polysaccharide export
CJO93_RS21420	COG0840	transmembrane signaling receptor activity
CJO93_RS21460	COG3220	belongs to the UPF0276 family
CJO93_RS21495	COG0745	RESPONSE REGULATOR receiver
CJO93_RS21520	COG2223	nitrite transmembrane transporter activity
CJO93_RS21525	COG0243	molybdopterin cofactor binding
CJO93_RS21535	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CJO93_RS21540	COG3300	MHYT domain
CJO93_RS21540	COG5001	Diguanylate cyclase
CJO93_RS21545	COG3158	transport of potassium into the cell
CJO93_RS21550	COG1278	Cold shock
CJO93_RS21560	COG3385	transposase activity
CJO93_RS21570	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CJO93_RS21580	COG4689	acetoacetate decarboxylase
CJO93_RS21585	COG1028	Short-chain dehydrogenase reductase Sdr
CJO93_RS21650	COG3210	domain, Protein
CJO93_RS21680	COG2831	hemolysin activation secretion protein
CJO93_RS21690	COG0673	inositol 2-dehydrogenase activity
CJO93_RS21745	COG4964	Belongs to the GSP D family
CJO93_RS21785	COG2197	response regulator
CJO93_RS21810	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CJO93_RS21815	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CJO93_RS21820	COG1877	trehalose-phosphatase activity
CJO93_RS21825	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CJO93_RS21830	COG1846	Transcriptional regulator
CJO93_RS21835	COG1764	response to oxidative stress
CJO93_RS21850	COG0583	DNA-binding transcription factor activity
CJO93_RS21860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CJO93_RS21905	COG2030	dehydratase
CJO93_RS21915	COG0604	alcohol dehydrogenase
CJO93_RS21915	COG3321	synthase
CJO93_RS21915	COG1028	Short-chain dehydrogenase reductase Sdr
CJO93_RS21925	COG0583	DNA-binding transcription factor activity
CJO93_RS21930	COG3039	Transposase
CJO93_RS21940	COG1064	alcohol dehydrogenase
CJO93_RS21965	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
CJO93_RS22000	COG1064	alcohol dehydrogenase
CJO93_RS22010	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CJO93_RS22015	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CJO93_RS22020	COG0640	Transcriptional regulator
CJO93_RS22070	COG5444	nuclease activity
CJO93_RS22090	COG2197	response regulator
CJO93_RS22100	COG2066	Belongs to the glutaminase family
CJO93_RS22105	COG4149	molybdate abc transporter
CJO93_RS22110	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CJO93_RS22125	COG5001	Diguanylate cyclase
CJO93_RS22125	COG3300	MHYT domain
CJO93_RS22145	COG3813	Protein conserved in bacteria
CJO93_RS22165	COG2205	protein histidine kinase activity
CJO93_RS22195	COG1858	cytochrome C peroxidase
CJO93_RS22215	COG1253	flavin adenine dinucleotide binding
CJO93_RS22220	COG1858	cytochrome C peroxidase
CJO93_RS22250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CJO93_RS22250	COG2205	protein histidine kinase activity
CJO93_RS22265	COG2274	protein secretion by the type I secretion system
CJO93_RS22290	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CJO93_RS22305	COG0800	Aldolase
CJO93_RS22310	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CJO93_RS22315	COG2197	response regulator
CJO93_RS22380	COG1294	oxidase, subunit
CJO93_RS22385	COG1271	oxidase subunit
CJO93_RS22390	COG3300	MHYT domain
CJO93_RS22390	COG5001	Diguanylate cyclase
CJO93_RS22395	COG0840	transmembrane signaling receptor activity
CJO93_RS22405	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CJO93_RS22415	COG0534	Mate efflux family protein
CJO93_RS22430	COG0243	molybdopterin cofactor binding
CJO93_RS22435	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CJO93_RS22445	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CJO93_RS22450	COG2223	nitrite transmembrane transporter activity
CJO93_RS22455	COG0840	transmembrane signaling receptor activity
CJO93_RS22460	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CJO93_RS22470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CJO93_RS22495	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CJO93_RS22500	COG0436	Aminotransferase
CJO93_RS22505	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CJO93_RS22505	COG0473	3-isopropylmalate dehydrogenase activity
CJO93_RS22540	COG3039	Transposase
CJO93_RS22550	COG2951	lytic endotransglycosylase activity
CJO93_RS22560	COG1271	oxidase subunit
CJO93_RS22565	COG1294	oxidase, subunit
CJO93_RS22570	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CJO93_RS22580	COG0251	oxidation-reduction process
CJO93_RS22615	COG3550	peptidyl-serine autophosphorylation
CJO93_RS22635	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CJO93_RS22655	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CJO93_RS22660	COG0730	response to heat
CJO93_RS22665	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CJO93_RS22675	COG0583	DNA-binding transcription factor activity
CJO93_RS22680	COG0730	response to heat
CJO93_RS22710	COG3039	Transposase
CJO93_RS22715	COG0668	transmembrane transport
CJO93_RS22720	COG1742	UPF0060 membrane protein
CJO93_RS22745	COG0477	Major facilitator Superfamily
CJO93_RS22750	COG0114	fumarate hydratase activity
CJO93_RS22775	COG1621	beta-fructofuranosidase activity
CJO93_RS22785	COG1609	Transcriptional regulator
CJO93_RS22820	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CJO93_RS22840	COG3766	membrane
CJO93_RS22860	COG0683	leucine binding
CJO93_RS22885	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CJO93_RS22975	COG0840	transmembrane signaling receptor activity
CJO93_RS22980	COG0567	Dehydrogenase, E1 component
CJO93_RS22985	COG0204	Acyl-transferase
CJO93_RS23000	COG4263	nitrous-oxide reductase activity
CJO93_RS23050	COG2831	hemolysin activation secretion protein
CJO93_RS23085	COG2824	Alkylphosphonate utilization operon protein PhnA
CJO93_RS23105	COG0762	integral membrane protein
CJO93_RS23130	COG1191	sigma factor activity
CJO93_RS23145	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CJO93_RS23155	COG1309	transcriptional regulator
CJO93_RS23160	COG2271	Major facilitator Superfamily
CJO93_RS23165	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CJO93_RS23170	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CJO93_RS23175	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CJO93_RS23185	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CJO93_RS23190	COG0745	RESPONSE REGULATOR receiver
CJO93_RS23195	COG2201	protein-glutamate methylesterase activity
CJO93_RS23200	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CJO93_RS23210	COG0840	transmembrane signaling receptor activity
CJO93_RS23215	COG0835	chemotaxis
CJO93_RS23225	COG0745	RESPONSE REGULATOR receiver
CJO93_RS23230	COG1360	Flagellar Motor Protein
CJO93_RS23265	COG0477	Major facilitator Superfamily
CJO93_RS23285	COG0776	regulation of translation
CJO93_RS23305	COG3039	Transposase
CJO93_RS23320	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CJO93_RS23330	COG0644	oxidoreductase
CJO93_RS23335	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CJO93_RS23340	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CJO93_RS23370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CJO93_RS23370	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CJO93_RS23405	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CJO93_RS23405	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CJO93_RS23410	COG1045	serine acetyltransferase
CJO93_RS23430	COG2205	protein histidine kinase activity
CJO93_RS23455	COG3039	Transposase
CJO93_RS23475	COG3039	Transposase
CJO93_RS23500	COG3039	Transposase
CJO93_RS23525	COG0667	Aldo Keto reductase
CJO93_RS23595	COG2192	nodulation
CJO93_RS23610	COG2192	nodulation
CJO93_RS23635	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CJO93_RS23635	COG4651	solute:proton antiporter activity
CJO93_RS23680	COG3256	nitric oxide reductase
CJO93_RS23685	COG2188	Transcriptional regulator
CJO93_RS23690	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CJO93_RS23695	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CJO93_RS23730	COG0583	DNA-binding transcription factor activity
CJO93_RS23840	COG3491	Belongs to the iron ascorbate-dependent oxidoreductase family
CJO93_RS23860	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CJO93_RS23870	COG3210	domain, Protein
CJO93_RS23915	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CJO93_RS23920	COG0642	Histidine kinase
CJO93_RS23940	COG0837	glucose binding
CJO93_RS23950	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CJO93_RS23960	COG0589	response to stress
CJO93_RS23975	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CJO93_RS23980	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CJO93_RS23990	COG1845	cytochrome c oxidase, subunit III
CJO93_RS24015	COG2271	Major facilitator Superfamily
CJO93_RS24030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CJO93_RS24040	COG0765	amino acid transport
CJO93_RS24045	COG0010	Belongs to the arginase family
CJO93_RS24050	COG2197	response regulator
CJO93_RS24075	COG4677	pectinesterase activity
CJO93_RS24085	COG0446	pyridine nucleotide-disulphide oxidoreductase
CJO93_RS24085	COG1902	pentaerythritol trinitrate reductase activity
CJO93_RS24100	COG0697	spore germination
CJO93_RS24145	COG0210	DNA helicase
CJO93_RS24150	COG3039	Transposase
CJO93_RS24165	COG2944	sequence-specific DNA binding
CJO93_RS24175	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CJO93_RS24220	COG0659	secondary active sulfate transmembrane transporter activity
CJO93_RS24225	COG0288	reversible hydration of carbon dioxide
CJO93_RS24240	COG0714	Associated with various cellular activities
CJO93_RS24255	COG0725	ABC transporter, periplasmic molybdate-binding protein
CJO93_RS24290	COG2814	Major facilitator Superfamily
CJO93_RS24295	COG3657	addiction module killer protein
CJO93_RS24300	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CJO93_RS24305	COG0477	Major facilitator Superfamily
CJO93_RS24340	COG4968	Prepilin-type N-terminal cleavage methylation domain
CJO93_RS24350	COG4796	Type ii and iii secretion system protein
CJO93_RS24375	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CJO93_RS24405	COG3039	Transposase
CJO93_RS24455	COG0038	chloride channel
CJO93_RS24470	COG1881	PFAM PEBP family protein
CJO93_RS24500	COG2916	Histone family protein nucleoid-structuring protein H-NS
CJO93_RS24525	COG1028	Short-chain dehydrogenase reductase Sdr
CJO93_RS24535	COG1024	Enoyl-CoA hydratase
CJO93_RS24540	COG1960	acyl-CoA dehydrogenase activity
CJO93_RS24615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CJO93_RS24620	COG1012	belongs to the aldehyde dehydrogenase family
CJO93_RS24630	COG0583	DNA-binding transcription factor activity
CJO93_RS24655	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CJO93_RS24660	COG2814	Major facilitator Superfamily
CJO93_RS24675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CJO93_RS24750	COG1012	belongs to the aldehyde dehydrogenase family
CJO93_RS24755	COG0473	3-isopropylmalate dehydrogenase activity
CJO93_RS24765	COG2271	Major facilitator Superfamily
CJO93_RS24770	COG2721	sulfolactate sulfo-lyase activity
CJO93_RS24780	COG1475	DNA binding
CJO93_RS24790	COG3969	phosphoadenosine phosphosulfate
CJO93_RS24795	COG5295	Hep Hag repeat protein
CJO93_RS24805	COG0784	Response regulator, receiver
CJO93_RS24805	COG2205	protein histidine kinase activity
CJO93_RS24810	COG4251	negative regulation of phosphorylation
CJO93_RS24810	COG2203	Gaf domain
CJO93_RS24810	COG5001	Diguanylate cyclase
CJO93_RS24810	COG3706	GGDEF domain
CJO93_RS24870	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
CJO93_RS24880	COG4213	ABC transporter substrate-binding protein
CJO93_RS24885	COG1129	ABC transporter
CJO93_RS24890	COG4214	carbohydrate transport
CJO93_RS24895	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CJO93_RS24900	COG1609	Transcriptional regulator
CJO93_RS24910	COG2207	Transcriptional regulator
CJO93_RS24990	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CJO93_RS25000	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CJO93_RS25010	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CJO93_RS25040	COG2204	response regulator
CJO93_RS25055	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CJO93_RS25075	COG2205	protein histidine kinase activity
CJO93_RS25085	COG2252	PERMEase