locus-tag	class	description
CJO83_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CJO83_RS00010	COG0592	DNA-directed DNA polymerase activity
CJO83_RS00125	COG3781	membrane
CJO83_RS00135	COG0840	transmembrane signaling receptor activity
CJO83_RS00150	COG0765	amino acid transport
CJO83_RS00155	COG1126	abc transporter atp-binding protein
CJO83_RS00160	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CJO83_RS00180	COG0642	Histidine kinase
CJO83_RS00195	COG2814	Major facilitator Superfamily
CJO83_RS00215	COG1959	2 iron, 2 sulfur cluster binding
CJO83_RS00240	COG0745	RESPONSE REGULATOR receiver
CJO83_RS00245	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CJO83_RS00265	COG5001	Diguanylate cyclase
CJO83_RS00265	COG2203	Gaf domain
CJO83_RS00265	COG3706	GGDEF domain
CJO83_RS00265	COG4251	negative regulation of phosphorylation
CJO83_RS00275	COG2205	protein histidine kinase activity
CJO83_RS00280	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CJO83_RS00285	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CJO83_RS00290	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CJO83_RS00325	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CJO83_RS00335	COG1116	anion transmembrane transporter activity
CJO83_RS00345	COG1254	Belongs to the acylphosphatase family
CJO83_RS00355	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CJO83_RS00360	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CJO83_RS00380	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CJO83_RS00385	COG2894	cell division
CJO83_RS00390	COG0850	regulation of cytokinetic process
CJO83_RS00395	COG0737	Belongs to the 5'-nucleotidase family
CJO83_RS00405	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CJO83_RS00430	COG2154	pterin-4-alpha-carbinolamine dehydratase
CJO83_RS00435	COG3186	Phenylalanine-4-hydroxylase
CJO83_RS00450	COG2423	ornithine cyclodeaminase activity
CJO83_RS00455	COG3047	cAMP biosynthetic process
CJO83_RS00465	COG2217	Heavy metal translocating P-type atpase
CJO83_RS00470	COG0789	Transcriptional regulator
CJO83_RS00475	COG2267	carboxylic ester hydrolase activity
CJO83_RS00540	COG3530	Putative quorum-sensing-regulated virulence factor
CJO83_RS00545	COG0583	DNA-binding transcription factor activity
CJO83_RS00565	COG0445	tRNA wobble uridine modification
CJO83_RS00570	COG0357	Ribosomal RNA small subunit methyltransferase G
CJO83_RS00575	COG1192	Involved in chromosome partitioning
CJO83_RS00580	COG1475	DNA binding
CJO83_RS00590	COG0356	it plays a direct role in the translocation of protons across the membrane
CJO83_RS00600	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CJO83_RS00605	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CJO83_RS00610	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CJO83_RS00615	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CJO83_RS00620	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CJO83_RS00625	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CJO83_RS00640	COG1832	CoA-binding protein
CJO83_RS00660	COG0625	glutathione transferase activity
CJO83_RS00690	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CJO83_RS00695	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CJO83_RS00700	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CJO83_RS00700	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CJO83_RS00700	COG0506	proline dehydrogenase activity
CJO83_RS00705	COG0683	leucine binding
CJO83_RS00715	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CJO83_RS00720	COG1297	OPT oligopeptide transporter protein
CJO83_RS00725	COG1760	l-serine dehydratase
CJO83_RS00730	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CJO83_RS00730	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CJO83_RS00735	COG0509	glycine decarboxylation via glycine cleavage system
CJO83_RS00740	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CJO83_RS00760	COG0210	DNA helicase
CJO83_RS00780	COG2197	response regulator
CJO83_RS00785	COG3916	Acyl-homoserine-lactone synthase
CJO83_RS00795	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CJO83_RS00800	COG2084	Dehydrogenase
CJO83_RS00805	COG3622	Belongs to the hyi family
CJO83_RS00810	COG3960	tartronate-semialdehyde synthase activity
CJO83_RS00815	COG0583	DNA-binding transcription factor activity
CJO83_RS00830	COG1739	Uncharacterized protein family UPF0029
CJO83_RS00840	COG1301	dicarboxylic acid transport
CJO83_RS00845	COG4266	Belongs to the allantoicase family
CJO83_RS00855	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CJO83_RS00880	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CJO83_RS00895	COG0792	nuclease activity
CJO83_RS00910	COG0446	pyridine nucleotide-disulphide oxidoreductase
CJO83_RS00920	COG4654	Cytochrome c, class I
CJO83_RS00945	COG2010	Cytochrome c
CJO83_RS00950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CJO83_RS00955	COG0737	Belongs to the 5'-nucleotidase family
CJO83_RS01015	COG3311	Transcriptional regulator
CJO83_RS01075	COG3609	addiction module antidote protein, CC2985 family
CJO83_RS01100	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CJO83_RS01200	COG2916	Histone family protein nucleoid-structuring protein H-NS
CJO83_RS01210	COG3039	Transposase
CJO83_RS01300	COG2831	hemolysin activation secretion protein
CJO83_RS01310	COG3668	Plasmid stabilization system
CJO83_RS01350	COG0529	Catalyzes the synthesis of activated sulfate
CJO83_RS01365	COG0457	Tetratricopeptide repeat
CJO83_RS01390	COG0493	'glutamate synthase
CJO83_RS01405	COG3385	transposase activity
CJO83_RS01410	COG1278	Cold shock
CJO83_RS01430	COG3039	Transposase
CJO83_RS01480	COG4251	negative regulation of phosphorylation
CJO83_RS01480	COG3706	GGDEF domain
CJO83_RS01480	COG2203	Gaf domain
CJO83_RS01480	COG5001	Diguanylate cyclase
CJO83_RS01495	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CJO83_RS01505	COG1028	Short-chain dehydrogenase reductase Sdr
CJO83_RS01515	COG0840	transmembrane signaling receptor activity
CJO83_RS01540	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CJO83_RS01550	COG3284	Transcriptional regulator
CJO83_RS01560	COG4303	Ethanolamine ammonia lyase large subunit
CJO83_RS01565	COG4302	ethanolamine ammonia-lyase activity
CJO83_RS01570	COG2925	Exonuclease
CJO83_RS01685	COG1522	sequence-specific DNA binding
CJO83_RS01695	COG1404	Belongs to the peptidase S8 family
CJO83_RS01720	COG0475	glutathione-regulated potassium exporter activity
CJO83_RS01720	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CJO83_RS01755	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CJO83_RS01760	COG3385	transposase activity
CJO83_RS01770	COG0745	RESPONSE REGULATOR receiver
CJO83_RS01825	COG2197	response regulator
CJO83_RS01830	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CJO83_RS01865	COG2814	Major facilitator Superfamily
CJO83_RS01870	COG0668	transmembrane transport
CJO83_RS01885	COG0745	RESPONSE REGULATOR receiver
CJO83_RS01890	COG2205	protein histidine kinase activity
CJO83_RS01920	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CJO83_RS01925	COG2336	PFAM SpoVT AbrB
CJO83_RS01945	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CJO83_RS01960	COG0395	ABC-type sugar transport system, permease component
CJO83_RS01970	COG3842	ATPase activity
CJO83_RS01975	COG3842	ATPase activity
CJO83_RS01985	COG1349	DNA-binding transcription factor activity
CJO83_RS02035	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CJO83_RS02055	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CJO83_RS02060	COG0081	regulation of translation
CJO83_RS02065	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CJO83_RS02070	COG0222	ribosome binding
CJO83_RS02075	COG0085	RNA polymerase activity
CJO83_RS02080	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CJO83_RS02085	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
CJO83_RS02090	COG3234	Protein of unknown function (DUF1175)
CJO83_RS02095	COG2373	Large extracellular alpha-helical protein
CJO83_RS02100	COG5445	Predicted secreted protein (DUF2300)
CJO83_RS02105	COG4676	Protein conserved in bacteria
CJO83_RS02110	COG4676	Protein conserved in bacteria
CJO83_RS02120	COG0514	ATP-dependent DNA helicase (RecQ)
CJO83_RS02125	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CJO83_RS02130	COG0049	tRNA binding
CJO83_RS02135	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CJO83_RS02140	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CJO83_RS02145	COG0051	transcription antitermination factor activity, RNA binding
CJO83_RS02150	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CJO83_RS02155	COG0088	Forms part of the polypeptide exit tunnel
CJO83_RS02160	COG0089	rRNA binding
CJO83_RS02165	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CJO83_RS02170	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CJO83_RS02175	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CJO83_RS02180	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CJO83_RS02185	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CJO83_RS02190	COG0255	Belongs to the universal ribosomal protein uL29 family
CJO83_RS02195	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CJO83_RS02200	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CJO83_RS02205	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CJO83_RS02210	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CJO83_RS02215	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CJO83_RS02220	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CJO83_RS02225	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CJO83_RS02230	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CJO83_RS02235	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CJO83_RS02240	COG1841	ribosomal large subunit assembly
CJO83_RS02245	COG0200	Binds to the 23S rRNA
CJO83_RS02250	COG0201	protein transport
CJO83_RS02255	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CJO83_RS02260	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CJO83_RS02265	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CJO83_RS02270	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CJO83_RS02275	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CJO83_RS02280	COG0202	RNA polymerase activity
CJO83_RS02285	COG0203	ribosomal protein L17
CJO83_RS02295	COG4232	protein-disulfide reductase activity
CJO83_RS02305	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CJO83_RS02315	COG1333	cytochrome c biogenesis protein
CJO83_RS02320	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CJO83_RS02340	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CJO83_RS02345	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CJO83_RS02360	COG1965	Belongs to the frataxin family
CJO83_RS02365	COG3385	transposase activity
CJO83_RS02400	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CJO83_RS02405	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CJO83_RS02410	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CJO83_RS02415	COG3047	cAMP biosynthetic process
CJO83_RS02425	COG0067	glutamate synthase
CJO83_RS02425	COG0069	glutamate synthase activity
CJO83_RS02425	COG0070	glutamate synthase
CJO83_RS02440	COG1127	ABC transporter
CJO83_RS02445	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CJO83_RS02450	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CJO83_RS02470	COG1131	(ABC) transporter
CJO83_RS02475	COG0842	Transport permease protein
CJO83_RS02485	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CJO83_RS02490	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CJO83_RS02495	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CJO83_RS02500	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CJO83_RS02505	COG0131	Imidazoleglycerol-phosphate dehydratase
CJO83_RS02510	COG2095	MarC family integral membrane protein
CJO83_RS02515	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CJO83_RS02520	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CJO83_RS02525	COG0107	imidazoleglycerol-phosphate synthase activity
CJO83_RS02530	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CJO83_RS02535	COG0140	phosphoribosyl-ATP diphosphatase activity
CJO83_RS02545	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CJO83_RS02550	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CJO83_RS02555	COG0805	protein transport
CJO83_RS02560	COG3842	ATPase activity
CJO83_RS02570	COG1840	ABC-type Fe3 transport system, periplasmic component
CJO83_RS02590	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CJO83_RS02595	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CJO83_RS02600	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CJO83_RS02605	COG1970	mechanosensitive ion channel activity
CJO83_RS02610	COG0723	plastoquinol--plastocyanin reductase activity
CJO83_RS02615	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CJO83_RS02620	COG2857	Cytochrome c1
CJO83_RS02625	COG0625	glutathione transferase activity
CJO83_RS02630	COG2969	positive regulation of protein catabolic process
CJO83_RS02655	COG0405	Gamma-glutamyltransferase
CJO83_RS02660	COG4774	siderophore transport
CJO83_RS02665	COG3712	iron ion homeostasis
CJO83_RS02675	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CJO83_RS02690	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CJO83_RS02695	COG0488	(ABC) transporter
CJO83_RS02715	COG2943	transferase activity, transferring hexosyl groups
CJO83_RS02715	COG3416	Protein conserved in bacteria
CJO83_RS02720	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CJO83_RS02735	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CJO83_RS02740	COG2890	protein-(glutamine-N5) methyltransferase activity
CJO83_RS02750	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CJO83_RS02755	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CJO83_RS02765	COG0012	GTP binding
CJO83_RS02790	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CJO83_RS02800	COG0604	alcohol dehydrogenase
CJO83_RS02810	COG1289	transmembrane transporter activity
CJO83_RS02825	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CJO83_RS02835	COG0134	indole-3-glycerol-phosphate synthase activity
CJO83_RS02840	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CJO83_RS02850	COG0512	Glutamine amidotransferase of anthranilate synthase
CJO83_RS02860	COG0546	phosphoglycolate phosphatase activity
CJO83_RS02865	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CJO83_RS02870	COG2967	ApaG domain
CJO83_RS02890	COG2050	protein possibly involved in aromatic compounds catabolism
CJO83_RS02895	COG1024	Enoyl-CoA hydratase
CJO83_RS02900	COG1024	Enoyl-CoA hydratase
CJO83_RS02930	COG1473	amidohydrolase
CJO83_RS02940	COG0601	transmembrane transport
CJO83_RS02945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CJO83_RS02950	COG0444	Belongs to the ABC transporter superfamily
CJO83_RS02955	COG4608	Belongs to the ABC transporter superfamily
CJO83_RS02960	COG3385	transposase activity
CJO83_RS02970	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CJO83_RS02970	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CJO83_RS02975	COG1105	Belongs to the carbohydrate kinase PfkB family
CJO83_RS02980	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CJO83_RS02980	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CJO83_RS02985	COG1609	Transcriptional regulator
CJO83_RS02990	COG0243	molybdopterin cofactor binding
CJO83_RS03000	COG0318	PFAM AMP-dependent synthetase and ligase
CJO83_RS03005	COG0477	Major facilitator Superfamily
CJO83_RS03010	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CJO83_RS03015	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
CJO83_RS03020	COG2001	Belongs to the MraZ family
CJO83_RS03025	COG0275	rRNA processing
CJO83_RS03040	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CJO83_RS03045	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CJO83_RS03050	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CJO83_RS03055	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CJO83_RS03065	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CJO83_RS03070	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CJO83_RS03075	COG1181	Belongs to the D-alanine--D-alanine ligase family
CJO83_RS03080	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CJO83_RS03095	COG0678	peroxiredoxin activity
CJO83_RS03100	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CJO83_RS03110	COG0739	heme binding
CJO83_RS03115	COG0653	protein targeting
CJO83_RS03120	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CJO83_RS03130	COG0494	nUDIX hydrolase
CJO83_RS03135	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CJO83_RS03140	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CJO83_RS03145	COG0237	dephospho-CoA kinase activity
CJO83_RS03155	COG1459	type II secretion system
CJO83_RS03165	COG4536	flavin adenine dinucleotide binding
CJO83_RS03175	COG0142	geranyltranstransferase activity
CJO83_RS03180	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CJO83_RS03185	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CJO83_RS03190	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CJO83_RS03195	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CJO83_RS03205	COG0494	nUDIX hydrolase
CJO83_RS03210	COG0442	prolyl-tRNA aminoacylation
CJO83_RS03215	COG0741	lytic transglycosylase activity
CJO83_RS03225	COG2095	MarC family integral membrane protein
CJO83_RS03230	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CJO83_RS03235	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CJO83_RS03260	COG3023	N-Acetylmuramoyl-L-alanine amidase
CJO83_RS03390	COG3039	Transposase
CJO83_RS03425	COG1522	sequence-specific DNA binding
CJO83_RS03435	COG0840	transmembrane signaling receptor activity
CJO83_RS03480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CJO83_RS03485	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CJO83_RS03495	COG2264	protein methyltransferase activity
CJO83_RS03505	COG0511	ligase activity, forming carbon-carbon bonds
CJO83_RS03510	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CJO83_RS03515	COG3118	belongs to the thioredoxin family
CJO83_RS03525	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CJO83_RS03530	COG3150	esterase
CJO83_RS03535	COG3161	chorismate lyase activity
CJO83_RS03540	COG0557	exoribonuclease II activity
CJO83_RS03550	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CJO83_RS03555	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CJO83_RS03570	COG0284	orotidine-5'-phosphate decarboxylase activity
CJO83_RS03580	COG1546	Belongs to the CinA family
CJO83_RS03580	COG1058	Belongs to the CinA family
CJO83_RS03585	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CJO83_RS03595	COG0280	phosphate acetyltransferase
CJO83_RS03595	COG0281	malic enzyme
CJO83_RS03615	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CJO83_RS03625	COG0583	DNA-binding transcription factor activity
CJO83_RS03630	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CJO83_RS03645	COG1129	ABC transporter
CJO83_RS03665	COG1028	Short-chain dehydrogenase reductase Sdr
CJO83_RS03670	COG0800	Aldolase
CJO83_RS03675	COG4948	Mandelate Racemase Muconate Lactonizing
CJO83_RS03680	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CJO83_RS03685	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CJO83_RS03690	COG0583	DNA-binding transcription factor activity
CJO83_RS03695	COG0735	belongs to the Fur family
CJO83_RS03700	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CJO83_RS03705	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CJO83_RS03710	COG0495	leucyl-tRNA aminoacylation
CJO83_RS03720	COG1466	dna polymerase III delta subunit
CJO83_RS03725	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CJO83_RS03730	COG1981	membrane
CJO83_RS03740	COG2204	response regulator
CJO83_RS03745	COG4191	Histidine kinase
CJO83_RS03750	COG4191	Histidine kinase
CJO83_RS03775	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CJO83_RS03815	COG0482	sulfurtransferase activity
CJO83_RS03820	COG0069	glutamate synthase activity
CJO83_RS03825	COG0625	glutathione transferase activity
CJO83_RS03835	COG3038	cytochrome b561
CJO83_RS03840	COG2353	YceI-like domain
CJO83_RS03845	COG2353	YceI-like domain
CJO83_RS03850	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CJO83_RS03855	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CJO83_RS03860	COG1862	Preprotein translocase
CJO83_RS03865	COG0343	queuine tRNA-ribosyltransferase activity
CJO83_RS03870	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CJO83_RS03875	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CJO83_RS03915	COG1522	sequence-specific DNA binding
CJO83_RS03920	COG1473	amidohydrolase
CJO83_RS03925	COG1819	glycosyl
CJO83_RS03950	COG3039	Transposase
CJO83_RS03980	COG1278	Cold shock
CJO83_RS04070	COG0783	Belongs to the Dps family
CJO83_RS04075	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CJO83_RS04135	COG0386	Belongs to the glutathione peroxidase family
CJO83_RS04155	COG1346	cytolysis
CJO83_RS04160	COG1380	Effector of murein hydrolase LrgA
CJO83_RS04165	COG0247	lactate metabolic process
CJO83_RS04170	COG0277	FAD linked oxidase domain protein
CJO83_RS04175	COG0277	FAD linked oxidase domain protein
CJO83_RS04180	COG0583	DNA-binding transcription factor activity
CJO83_RS04185	COG0277	FAD linked oxidase domain protein
CJO83_RS04190	COG2096	Adenosyltransferase
CJO83_RS04195	COG0668	transmembrane transport
CJO83_RS04205	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CJO83_RS04210	COG0312	modulator of DNA gyrase
CJO83_RS04215	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CJO83_RS04225	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CJO83_RS04240	COG1404	Belongs to the peptidase S8 family
CJO83_RS04250	COG0497	DNA recombination
CJO83_RS04255	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CJO83_RS04260	COG1420	regulation of RNA biosynthetic process
CJO83_RS04270	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CJO83_RS04275	COG2986	histidine ammonia-lyase
CJO83_RS04280	COG0010	Belongs to the arginase family
CJO83_RS04285	COG1228	amidohydrolase
CJO83_RS04290	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CJO83_RS04310	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CJO83_RS04320	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CJO83_RS04325	COG0443	Heat shock 70 kDa protein
CJO83_RS04330	COG0484	heat shock protein binding
CJO83_RS04335	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CJO83_RS04335	COG0512	Glutamine amidotransferase of anthranilate synthase
CJO83_RS04340	COG1122	ATPase activity
CJO83_RS04345	COG4662	Binding-protein-dependent transport system inner membrane component
CJO83_RS04350	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CJO83_RS04360	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CJO83_RS04375	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CJO83_RS04380	COG0628	permease
CJO83_RS04385	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CJO83_RS04400	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CJO83_RS04400	COG2169	Transcriptional regulator
CJO83_RS04420	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CJO83_RS04420	COG2169	Transcriptional regulator
CJO83_RS04425	COG0456	acetyltransferase
CJO83_RS04430	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CJO83_RS04435	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CJO83_RS04440	COG3008	intermembrane lipid transfer
CJO83_RS04455	COG0586	Pfam SNARE associated Golgi protein
CJO83_RS04465	COG0728	peptidoglycan biosynthetic process
CJO83_RS04470	COG0268	Binds directly to 16S ribosomal RNA
CJO83_RS04480	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CJO83_RS04490	COG0137	argininosuccinate synthase activity
CJO83_RS04495	COG3123	guanosine phosphorylase activity
CJO83_RS04505	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CJO83_RS04510	COG1666	GTP binding
CJO83_RS04525	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CJO83_RS04535	COG4974	Belongs to the 'phage' integrase family
CJO83_RS04550	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CJO83_RS04555	COG0802	atpase or kinase
CJO83_RS04560	COG0860	N-Acetylmuramoyl-L-alanine amidase
CJO83_RS04570	COG0583	DNA-binding transcription factor activity
CJO83_RS04590	COG0563	adenylate kinase activity
CJO83_RS04595	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CJO83_RS04600	COG2835	tetraacyldisaccharide 4'-kinase activity
CJO83_RS04605	COG1663	tetraacyldisaccharide 4'-kinase activity
CJO83_RS04615	COG0811	peptide transport
CJO83_RS04620	COG1570	exodeoxyribonuclease VII activity
CJO83_RS04625	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CJO83_RS04670	COG2610	gluconate transmembrane transporter activity
CJO83_RS04725	COG1473	amidohydrolase
CJO83_RS04760	COG1028	Short-chain dehydrogenase reductase Sdr
CJO83_RS04765	COG2321	neutral zinc metallopeptidase
CJO83_RS04780	COG2259	Doxx family
CJO83_RS04790	COG0583	DNA-binding transcription factor activity
CJO83_RS04795	COG0583	DNA-binding transcription factor activity
CJO83_RS04815	COG1858	cytochrome C peroxidase
CJO83_RS04835	COG0582	viral genome integration into host DNA
CJO83_RS04915	COG1278	Cold shock
CJO83_RS04920	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CJO83_RS04925	COG0542	response to heat
CJO83_RS04930	COG0756	dUTP diphosphatase activity
CJO83_RS04935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CJO83_RS04940	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CJO83_RS04950	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CJO83_RS04955	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CJO83_RS04960	COG0196	riboflavin kinase activity
CJO83_RS04965	COG5002	protein histidine kinase activity
CJO83_RS04965	COG0784	Response regulator, receiver
CJO83_RS04970	COG2197	response regulator
CJO83_RS04975	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CJO83_RS04980	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CJO83_RS04980	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CJO83_RS04990	COG1511	domain protein
CJO83_RS04990	COG3264	Mechanosensitive ion channel
CJO83_RS05000	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CJO83_RS05010	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CJO83_RS05015	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CJO83_RS05020	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CJO83_RS05025	COG2003	Belongs to the UPF0758 family
CJO83_RS05030	COG1047	Peptidyl-prolyl cis-trans
CJO83_RS05035	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CJO83_RS05070	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CJO83_RS05105	COG2084	Dehydrogenase
CJO83_RS05115	COG0583	DNA-binding transcription factor activity
CJO83_RS05125	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CJO83_RS05135	COG0175	sulfate reduction
CJO83_RS05145	COG2895	sulfate adenylyltransferase (ATP) activity
CJO83_RS05175	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CJO83_RS05190	COG3385	transposase activity
CJO83_RS05195	COG0129	dihydroxy-acid dehydratase activity
CJO83_RS05200	COG0583	DNA-binding transcription factor activity
CJO83_RS05205	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CJO83_RS05235	COG4206	TonB-dependent receptor
CJO83_RS05245	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CJO83_RS05250	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CJO83_RS05255	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CJO83_RS05265	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CJO83_RS05275	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CJO83_RS05285	COG1492	cobalamin metabolic process
CJO83_RS05300	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CJO83_RS05305	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CJO83_RS05320	COG2911	Protein conserved in bacteria
CJO83_RS05330	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CJO83_RS05330	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CJO83_RS05335	COG2885	chlorophyll binding
CJO83_RS05335	COG3047	cAMP biosynthetic process
CJO83_RS05340	COG0489	protein tyrosine kinase activity
CJO83_RS05370	COG3383	formate dehydrogenase (NAD+) activity
CJO83_RS05370	COG0243	molybdopterin cofactor binding
CJO83_RS05375	COG0437	4 iron, 4 sulfur cluster binding
CJO83_RS05395	COG2032	superoxide dismutase activity
CJO83_RS05400	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CJO83_RS05405	COG0717	Belongs to the dCTP deaminase family
CJO83_RS05450	COG0165	Argininosuccinate lyase
CJO83_RS05475	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CJO83_RS05480	COG0181	hydroxymethylbilane synthase activity
CJO83_RS05505	COG2271	Major facilitator Superfamily
CJO83_RS05520	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CJO83_RS05560	COG0492	ferredoxin-NADP+ reductase activity
CJO83_RS05565	COG1674	ftsk spoiiie
CJO83_RS05570	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CJO83_RS05580	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CJO83_RS05585	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CJO83_RS05595	COG0582	viral genome integration into host DNA
CJO83_RS05725	COG0556	nucleotide-excision repair
CJO83_RS05760	COG5377	YqaJ viral recombinase family
CJO83_RS05855	COG1846	Transcriptional regulator
CJO83_RS05865	COG2814	Major facilitator Superfamily
CJO83_RS05875	COG1028	Short-chain dehydrogenase reductase Sdr
CJO83_RS05880	COG1522	sequence-specific DNA binding
CJO83_RS05890	COG1522	sequence-specific DNA binding
CJO83_RS05900	COG2814	Major facilitator Superfamily
CJO83_RS05915	COG2197	response regulator
CJO83_RS05970	COG2165	general secretion pathway protein
CJO83_RS06040	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CJO83_RS06090	COG1253	flavin adenine dinucleotide binding
CJO83_RS06145	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CJO83_RS06160	COG0765	amino acid transport
CJO83_RS06165	COG0765	amino acid transport
CJO83_RS06170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CJO83_RS06180	COG1414	Transcriptional regulator
CJO83_RS06190	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CJO83_RS06195	COG0183	Belongs to the thiolase family
CJO83_RS06205	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CJO83_RS06210	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CJO83_RS06225	COG0411	ABC transporter
CJO83_RS06235	COG0683	leucine binding
CJO83_RS06250	COG2342	PFAM TM1410 hypothetical-related protein
CJO83_RS06275	COG0525	valine-tRNA ligase activity
CJO83_RS06280	COG0210	DNA helicase
CJO83_RS06290	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CJO83_RS06300	COG1611	Belongs to the LOG family
CJO83_RS06305	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CJO83_RS06305	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CJO83_RS06310	COG1252	NADH dehydrogenase
CJO83_RS06315	COG0412	Dienelactone hydrolase
CJO83_RS06325	COG3385	transposase activity
CJO83_RS06345	COG1722	exodeoxyribonuclease VII activity
CJO83_RS06350	COG0142	geranyltranstransferase activity
CJO83_RS06355	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CJO83_RS06360	COG1469	GTP cyclohydrolase I activity
CJO83_RS06365	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CJO83_RS06370	COG2081	HI0933 family
CJO83_RS06375	COG1610	YqeY-like protein
CJO83_RS06395	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CJO83_RS06405	COG0426	domain, Protein
CJO83_RS06405	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CJO83_RS06410	COG0513	Belongs to the DEAD box helicase family
CJO83_RS06415	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CJO83_RS06420	COG0583	DNA-binding transcription factor activity
CJO83_RS06425	COG1741	Belongs to the pirin family
CJO83_RS06435	COG1054	Belongs to the UPF0176 family
CJO83_RS06455	COG0463	Glycosyl transferase, family 2
CJO83_RS06465	COG1132	(ABC) transporter
CJO83_RS06485	COG1530	ribonuclease E activity
CJO83_RS06490	COG0424	maF-like protein
CJO83_RS06495	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CJO83_RS06500	COG0799	negative regulation of ribosome biogenesis
CJO83_RS06510	COG0408	coproporphyrinogen oxidase activity
CJO83_RS06515	COG0151	Belongs to the GarS family
CJO83_RS06520	COG0217	transcriptional regulatory protein
CJO83_RS06525	COG0433	COG0433 Predicted ATPase
CJO83_RS06530	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CJO83_RS06535	COG0697	spore germination
CJO83_RS06540	COG1028	Short-chain dehydrogenase reductase Sdr
CJO83_RS06545	COG1803	Methylglyoxal synthase
CJO83_RS06595	COG4603	Belongs to the binding-protein-dependent transport system permease family
CJO83_RS06600	COG3845	ABC transporter
CJO83_RS06605	COG2814	Major facilitator Superfamily
CJO83_RS06610	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CJO83_RS06615	COG1984	allophanate hydrolase subunit 2
CJO83_RS06620	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CJO83_RS06635	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CJO83_RS06640	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CJO83_RS06655	COG1234	tRNA 3'-trailer cleavage
CJO83_RS06665	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CJO83_RS06670	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CJO83_RS06675	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CJO83_RS06685	COG4991	sh3 domain protein
CJO83_RS06685	COG0515	serine threonine protein kinase
CJO83_RS06685	COG3064	Membrane
CJO83_RS06690	COG1561	YicC-like family, N-terminal region
CJO83_RS06695	COG0194	GDP metabolic process
CJO83_RS06700	COG1758	RNA polymerase activity
CJO83_RS06705	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CJO83_RS06735	COG1652	LysM domain
CJO83_RS06745	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CJO83_RS06770	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CJO83_RS06775	COG3842	ATPase activity
CJO83_RS06785	COG1733	regulation of RNA biosynthetic process
CJO83_RS06795	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CJO83_RS06820	COG0246	Mannitol dehydrogenase
CJO83_RS06825	COG1070	Carbohydrate kinase
CJO83_RS06830	COG2390	Transcriptional regulator
CJO83_RS06840	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CJO83_RS06845	COG0308	aminopeptidase N
CJO83_RS06855	COG0280	phosphate acetyltransferase
CJO83_RS06855	COG0281	malic enzyme
CJO83_RS06865	COG3195	allantoin biosynthetic process
CJO83_RS06865	COG3648	Uricase
CJO83_RS06880	COG2233	PERMEase
CJO83_RS06890	COG2351	hydroxyisourate hydrolase activity
CJO83_RS06905	COG3039	Transposase
CJO83_RS06910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CJO83_RS06925	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CJO83_RS06930	COG1012	belongs to the aldehyde dehydrogenase family
CJO83_RS06940	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CJO83_RS06950	COG1126	abc transporter atp-binding protein
CJO83_RS06955	COG0765	amino acid transport
CJO83_RS06960	COG0765	amino acid transport
CJO83_RS06970	COG2186	Transcriptional regulator
CJO83_RS06990	COG2119	membrane
CJO83_RS06995	COG0402	S-adenosylhomocysteine deaminase activity
CJO83_RS07000	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CJO83_RS07010	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CJO83_RS07035	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CJO83_RS07060	COG1309	transcriptional regulator
CJO83_RS07070	COG0438	transferase activity, transferring glycosyl groups
CJO83_RS07105	COG0028	Belongs to the TPP enzyme family
CJO83_RS07115	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CJO83_RS07120	COG0688	phosphatidylethanolamine metabolic process
CJO83_RS07125	COG1183	phosphatidylcholine synthase activity
CJO83_RS07130	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CJO83_RS07140	COG0683	leucine binding
CJO83_RS07145	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CJO83_RS07150	COG1185	polyribonucleotide nucleotidyltransferase activity
CJO83_RS07165	COG0149	triose-phosphate isomerase activity
CJO83_RS07170	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CJO83_RS07180	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CJO83_RS07185	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CJO83_RS07190	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CJO83_RS07195	COG0649	NAD binding
CJO83_RS07210	COG1034	ATP synthesis coupled electron transport
CJO83_RS07215	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CJO83_RS07220	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CJO83_RS07230	COG0713	ATP synthesis coupled electron transport
CJO83_RS07245	COG1007	ATP synthesis coupled electron transport
CJO83_RS07270	COG1960	acyl-CoA dehydrogenase activity
CJO83_RS07275	COG2030	dehydratase
CJO83_RS07275	COG1012	belongs to the aldehyde dehydrogenase family
CJO83_RS07310	COG0829	nickel cation binding
CJO83_RS07315	COG0831	urea catabolic process
CJO83_RS07325	COG0832	Belongs to the urease beta subunit family
CJO83_RS07330	COG0804	urea catabolic process
CJO83_RS07335	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CJO83_RS07340	COG0830	nickel cation binding
CJO83_RS07345	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CJO83_RS07370	COG0625	glutathione transferase activity
CJO83_RS07375	COG1960	acyl-CoA dehydrogenase activity
CJO83_RS07405	COG1024	Enoyl-CoA hydratase
CJO83_RS07410	COG1250	3-hydroxyacyl-CoA dehydrogenase
CJO83_RS07415	COG0625	glutathione transferase activity
CJO83_RS07420	COG0436	Aminotransferase
CJO83_RS07430	COG3022	response to hydroperoxide
CJO83_RS07435	COG2866	Carboxypeptidase
CJO83_RS07445	COG0747	negative chemotaxis
CJO83_RS07460	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CJO83_RS07485	COG0039	L-malate dehydrogenase activity
CJO83_RS07490	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CJO83_RS07495	COG2009	succinate dehydrogenase
CJO83_RS07500	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CJO83_RS07505	COG1053	succinate dehydrogenase
CJO83_RS07510	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CJO83_RS07515	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CJO83_RS07520	COG0372	Belongs to the citrate synthase family
CJO83_RS07525	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CJO83_RS07530	COG0066	3-isopropylmalate dehydratase activity
CJO83_RS07535	COG0473	3-isopropylmalate dehydrogenase activity
CJO83_RS07550	COG0101	tRNA pseudouridine synthase activity
CJO83_RS07555	COG0135	phosphoribosylanthranilate isomerase activity
CJO83_RS07560	COG0133	tryptophan synthase activity
CJO83_RS07570	COG0159	tryptophan synthase activity
CJO83_RS07575	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CJO83_RS07580	COG0285	dihydrofolate synthase activity
CJO83_RS07600	COG0842	Transport permease protein
CJO83_RS07605	COG1131	(ABC) transporter
CJO83_RS07635	COG3193	protein, possibly involved in utilization of glycolate and propanediol
CJO83_RS07680	COG1301	dicarboxylic acid transport
CJO83_RS07685	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CJO83_RS07700	COG0697	spore germination
CJO83_RS07705	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CJO83_RS07710	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CJO83_RS07720	COG3039	Transposase
CJO83_RS07730	COG2197	response regulator
CJO83_RS07735	COG0840	transmembrane signaling receptor activity
CJO83_RS07775	COG0747	negative chemotaxis
CJO83_RS07795	COG0601	transmembrane transport
CJO83_RS07800	COG2072	flavoprotein involved in K transport
CJO83_RS07845	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CJO83_RS07855	COG0582	viral genome integration into host DNA
CJO83_RS07885	COG0656	L-ascorbic acid biosynthetic process
CJO83_RS07890	COG2304	oxidoreductase activity
CJO83_RS07905	COG0589	response to stress
CJO83_RS07940	COG0328	RNA-DNA hybrid ribonuclease activity
CJO83_RS07945	COG2226	methyltransferase
CJO83_RS07950	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CJO83_RS07955	COG1388	LysM domain
CJO83_RS07955	COG0741	lytic transglycosylase activity
CJO83_RS07960	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CJO83_RS07965	COG0505	Belongs to the CarA family
CJO83_RS07975	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CJO83_RS07980	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CJO83_RS07990	COG1534	Rna-binding protein
CJO83_RS07995	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CJO83_RS08000	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CJO83_RS08005	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CJO83_RS08010	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CJO83_RS08015	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CJO83_RS08020	COG0573	inorganic phosphate transmembrane transporter activity
CJO83_RS08025	COG0581	inorganic phosphate transmembrane transporter activity
CJO83_RS08030	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CJO83_RS08040	COG0745	RESPONSE REGULATOR receiver
CJO83_RS08050	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CJO83_RS08055	COG0248	Ppx GppA phosphatase
CJO83_RS08080	COG0730	response to heat
CJO83_RS08090	COG0640	Transcriptional regulator
CJO83_RS08100	COG5001	Diguanylate cyclase
CJO83_RS08100	COG3300	MHYT domain
CJO83_RS08235	COG0277	FAD linked oxidase domain protein
CJO83_RS08250	COG1295	ribonuclease BN
CJO83_RS08275	COG0477	Major facilitator Superfamily
CJO83_RS08280	COG0545	Peptidyl-prolyl cis-trans isomerase
CJO83_RS08285	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CJO83_RS08295	COG1028	Short-chain dehydrogenase reductase Sdr
CJO83_RS08300	COG4566	intracellular signal transduction
CJO83_RS08315	COG1028	Short-chain dehydrogenase reductase Sdr
CJO83_RS08325	COG0251	oxidation-reduction process
CJO83_RS08330	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CJO83_RS08340	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CJO83_RS08345	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CJO83_RS08350	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CJO83_RS08355	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CJO83_RS08360	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CJO83_RS08365	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CJO83_RS08365	COG0072	phenylalanine-tRNA ligase activity
CJO83_RS08370	COG0776	regulation of translation
CJO83_RS08395	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CJO83_RS08400	COG0531	amino acid
CJO83_RS08420	COG1846	Transcriptional regulator
CJO83_RS08430	COG0402	S-adenosylhomocysteine deaminase activity
CJO83_RS08435	COG0339	signal peptide processing
CJO83_RS08440	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CJO83_RS08445	COG4566	intracellular signal transduction
CJO83_RS08460	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CJO83_RS08465	COG0508	dehydrogenase complex catalyzes the overall conversion of
CJO83_RS08475	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CJO83_RS08490	COG0123	including yeast histone deacetylase and acetoin utilization protein
CJO83_RS08515	COG1414	Transcriptional regulator
CJO83_RS08540	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CJO83_RS08545	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CJO83_RS08565	COG0167	dihydroorotate dehydrogenase activity
CJO83_RS08575	COG3158	transport of potassium into the cell
CJO83_RS08585	COG2183	response to ionizing radiation
CJO83_RS08600	COG1199	ATP-dependent helicase activity
CJO83_RS08610	COG0564	pseudouridine synthase activity
CJO83_RS08625	COG3243	poly(R)-hydroxyalkanoic acid synthase
CJO83_RS08630	COG0183	Belongs to the thiolase family
CJO83_RS08635	COG1028	Short-chain dehydrogenase reductase Sdr
CJO83_RS08645	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CJO83_RS08650	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CJO83_RS08655	COG0183	Belongs to the thiolase family
CJO83_RS08670	COG0560	Phosphoserine phosphatase
CJO83_RS08680	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CJO83_RS08685	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CJO83_RS08690	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CJO83_RS08695	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CJO83_RS08700	COG0450	alkyl hydroperoxide reductase
CJO83_RS08730	COG1562	ergosterol biosynthetic process
CJO83_RS08735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CJO83_RS08755	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CJO83_RS08755	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CJO83_RS08760	COG0544	peptidyl-prolyl cis-trans isomerase activity
CJO83_RS08765	COG0740	serine-type endopeptidase activity
CJO83_RS08770	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CJO83_RS08775	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CJO83_RS08780	COG0776	regulation of translation
CJO83_RS08795	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CJO83_RS08800	COG3385	transposase activity
CJO83_RS08815	COG4181	ATPase activity
CJO83_RS08820	COG0166	Belongs to the GPI family
CJO83_RS08825	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CJO83_RS08835	COG0047	phosphoribosylformylglycinamidine synthase activity
CJO83_RS08835	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CJO83_RS08855	COG0535	radical SAM domain protein
CJO83_RS08875	COG0583	DNA-binding transcription factor activity
CJO83_RS08880	COG1028	Short-chain dehydrogenase reductase Sdr
CJO83_RS08890	COG1176	ABC-type spermidine putrescine transport system, permease component I
CJO83_RS08900	COG3842	ATPase activity
CJO83_RS08905	COG0642	Histidine kinase
CJO83_RS08915	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CJO83_RS08920	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CJO83_RS08945	COG1126	abc transporter atp-binding protein
CJO83_RS08950	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CJO83_RS08960	COG2917	probably involved in intracellular septation
CJO83_RS08965	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CJO83_RS08970	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CJO83_RS08975	COG0318	PFAM AMP-dependent synthetase and ligase
CJO83_RS08985	COG0559	Belongs to the binding-protein-dependent transport system permease family
CJO83_RS09015	COG0833	amino acid
CJO83_RS09020	COG0833	amino acid
CJO83_RS09030	COG1335	isochorismatase
CJO83_RS09035	COG0183	Belongs to the thiolase family
CJO83_RS09045	COG1028	Short-chain dehydrogenase reductase Sdr
CJO83_RS09060	COG2130	NADP-dependent
CJO83_RS09080	COG0596	Alpha beta hydrolase
CJO83_RS09115	COG2831	hemolysin activation secretion protein
CJO83_RS09135	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CJO83_RS09140	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CJO83_RS09145	COG0470	DNA polymerase III
CJO83_RS09155	COG0084	hydrolase, TatD family'
CJO83_RS09165	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CJO83_RS09170	COG1609	Transcriptional regulator
CJO83_RS09175	COG1840	ABC-type Fe3 transport system, periplasmic component
CJO83_RS09185	COG4208	sulfate ABC transporter
CJO83_RS09190	COG3842	ATPase activity
CJO83_RS09195	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CJO83_RS09200	COG3023	N-Acetylmuramoyl-L-alanine amidase
CJO83_RS09235	COG0038	chloride channel
CJO83_RS09240	COG2226	methyltransferase
CJO83_RS09250	COG3433	isochorismatase activity
CJO83_RS09250	COG2226	methyltransferase
CJO83_RS09250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CJO83_RS09255	COG4771	TonB-dependent receptor
CJO83_RS09260	COG1132	(ABC) transporter
CJO83_RS09260	COG2375	cellular response to nickel ion
CJO83_RS09275	COG3433	isochorismatase activity
CJO83_RS09275	COG2226	methyltransferase
CJO83_RS09275	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CJO83_RS09295	COG0456	acetyltransferase
CJO83_RS09340	COG0179	Fumarylacetoacetate (FAA) hydrolase
CJO83_RS09385	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CJO83_RS09415	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CJO83_RS09435	COG2801	Transposase and inactivated derivatives
CJO83_RS09465	COG2814	Major facilitator Superfamily
CJO83_RS09490	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CJO83_RS09500	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CJO83_RS09545	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CJO83_RS09550	COG0156	8-amino-7-oxononanoate synthase activity
CJO83_RS09585	COG3045	CreA protein
CJO83_RS09620	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CJO83_RS09635	COG0840	transmembrane signaling receptor activity
CJO83_RS09645	COG3387	PFAM Glycoside hydrolase 15-related
CJO83_RS09670	COG0488	(ABC) transporter
CJO83_RS09675	COG1619	proteins homologs of microcin C7 resistance protein MccF
CJO83_RS09685	COG0720	synthase
CJO83_RS09690	COG0602	queuosine metabolic process
CJO83_RS09710	COG3550	peptidyl-serine autophosphorylation
CJO83_RS09730	COG3485	protocatechuate 3,4-dioxygenase
CJO83_RS09735	COG3485	protocatechuate 3,4-dioxygenase
CJO83_RS09740	COG0583	DNA-binding transcription factor activity
CJO83_RS09790	COG0519	Catalyzes the synthesis of GMP from XMP
CJO83_RS09790	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CJO83_RS09805	COG0697	spore germination
CJO83_RS09815	COG2914	Belongs to the UPF0125 (RnfH) family
CJO83_RS09820	COG2867	negative regulation of translational initiation
CJO83_RS09825	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CJO83_RS09830	COG0330	HflC and HflK could
CJO83_RS09845	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CJO83_RS09850	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CJO83_RS09855	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CJO83_RS09860	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CJO83_RS09865	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CJO83_RS09870	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CJO83_RS09875	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CJO83_RS09890	COG0750	zinc metalloprotease
CJO83_RS09895	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CJO83_RS09900	COG0575	Belongs to the CDS family
CJO83_RS09905	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CJO83_RS09910	COG0233	cytoplasmic translational termination
CJO83_RS09915	COG0528	UMP kinase activity
CJO83_RS09920	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CJO83_RS09925	COG0052	Belongs to the universal ribosomal protein uS2 family
CJO83_RS09930	COG0024	Methionine aminopeptidase
CJO83_RS09935	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CJO83_RS09940	COG1187	pseudouridine synthase activity
CJO83_RS09950	COG0242	peptide deformylase activity
CJO83_RS09955	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CJO83_RS09970	COG0596	Alpha beta hydrolase
CJO83_RS09985	COG2171	N-acyltransferase activity
CJO83_RS09995	COG1393	Belongs to the ArsC family
CJO83_RS10000	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CJO83_RS10010	COG2890	protein-(glutamine-N5) methyltransferase activity
CJO83_RS10015	COG0302	gtp cyclohydrolase
CJO83_RS10040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CJO83_RS10045	COG0601	transmembrane transport
CJO83_RS10050	COG0747	negative chemotaxis
CJO83_RS10055	COG4172	Belongs to the ABC transporter superfamily
CJO83_RS10070	COG0488	(ABC) transporter
CJO83_RS10080	COG1683	Conserved Protein
CJO83_RS10085	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CJO83_RS10095	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CJO83_RS10100	COG0477	Major facilitator Superfamily
CJO83_RS10105	COG1573	uracil-dna glycosylase
CJO83_RS10110	COG0456	acetyltransferase
CJO83_RS10115	COG1214	PFAM Peptidase M22, glycoprotease
CJO83_RS10125	COG2814	Major facilitator Superfamily
CJO83_RS10135	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CJO83_RS10150	COG0583	DNA-binding transcription factor activity
CJO83_RS10160	COG2224	Isocitrate lyase
CJO83_RS10180	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CJO83_RS10195	COG3275	phosphorelay sensor kinase activity
CJO83_RS10220	COG0583	DNA-binding transcription factor activity
CJO83_RS10225	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CJO83_RS10230	COG4208	sulfate ABC transporter
CJO83_RS10255	COG1116	anion transmembrane transporter activity
CJO83_RS10260	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CJO83_RS10265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CJO83_RS10270	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CJO83_RS10275	COG0431	NADPH-dependent FMN reductase
CJO83_RS10280	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CJO83_RS10285	COG2985	domain, Protein
CJO83_RS10290	COG0281	malic enzyme
CJO83_RS10305	COG4191	Histidine kinase
CJO83_RS10315	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CJO83_RS10325	COG0542	response to heat
CJO83_RS10335	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CJO83_RS10340	COG0314	molybdopterin synthase activity
CJO83_RS10345	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CJO83_RS10350	COG0303	'Molybdopterin
CJO83_RS10355	COG1573	uracil-dna glycosylase
CJO83_RS10370	COG0436	Aminotransferase
CJO83_RS10380	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CJO83_RS10385	COG2076	Multidrug Resistance protein
CJO83_RS10390	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CJO83_RS10405	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CJO83_RS10405	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CJO83_RS10415	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CJO83_RS10420	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CJO83_RS10430	COG0791	NLP P60 protein
CJO83_RS10435	COG0306	phosphate transporter
CJO83_RS10445	COG0305	Participates in initiation and elongation during chromosome replication
CJO83_RS10450	COG0359	binds to the 23S rRNA
CJO83_RS10455	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CJO83_RS10465	COG0360	Binds together with S18 to 16S ribosomal RNA
CJO83_RS10480	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CJO83_RS10495	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CJO83_RS10520	COG1024	Enoyl-CoA hydratase
CJO83_RS10530	COG1217	gtp-binding protein TYPA
CJO83_RS10545	COG1566	PFAM secretion protein HlyD family protein
CJO83_RS10550	COG2814	Major facilitator Superfamily
CJO83_RS10555	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CJO83_RS10560	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CJO83_RS10565	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CJO83_RS10570	COG2251	uridine kinase activity
CJO83_RS10570	COG0195	Participates in both transcription termination and antitermination
CJO83_RS10575	COG0779	Required for maturation of 30S ribosomal subunits
CJO83_RS10580	COG1187	pseudouridine synthase activity
CJO83_RS10585	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CJO83_RS10595	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CJO83_RS10630	COG3278	Belongs to the heme-copper respiratory oxidase family
CJO83_RS10640	COG2217	Heavy metal translocating P-type atpase
CJO83_RS10650	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CJO83_RS10655	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CJO83_RS10660	COG0508	dehydrogenase complex catalyzes the overall conversion of
CJO83_RS10665	COG0567	Dehydrogenase, E1 component
CJO83_RS10670	COG0584	glycerophosphoryl diester phosphodiesterase
CJO83_RS10675	COG3842	ATPase activity
CJO83_RS10685	COG1175	transmembrane transport
CJO83_RS10690	COG1653	transport
CJO83_RS10705	COG2204	response regulator
CJO83_RS10720	COG0174	glutamine synthetase
CJO83_RS10730	COG1546	Belongs to the CinA family
CJO83_RS10730	COG1058	Belongs to the CinA family
CJO83_RS10755	COG1643	Atp-dependent helicase
CJO83_RS10760	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CJO83_RS10760	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CJO83_RS10765	COG1737	Transcriptional regulator
CJO83_RS10770	COG0673	inositol 2-dehydrogenase activity
CJO83_RS10780	COG0673	inositol 2-dehydrogenase activity
CJO83_RS10790	COG1082	Xylose isomerase domain protein TIM barrel
CJO83_RS10795	COG1172	Belongs to the binding-protein-dependent transport system permease family
CJO83_RS10800	COG1129	ABC transporter
CJO83_RS10810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CJO83_RS10815	COG3962	Belongs to the TPP enzyme family
CJO83_RS10825	COG3718	enzyme involved in inositol metabolism
CJO83_RS10835	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CJO83_RS10845	COG1953	Uracil, thiamine, allantoin
CJO83_RS10850	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CJO83_RS10855	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CJO83_RS10860	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CJO83_RS10865	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CJO83_RS10870	COG0557	exoribonuclease II activity
CJO83_RS10880	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CJO83_RS10885	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CJO83_RS10890	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CJO83_RS10900	COG0330	HflC and HflK could
CJO83_RS10905	COG0330	HflC and HflK could
CJO83_RS10910	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CJO83_RS10915	COG1923	regulation of RNA biosynthetic process
CJO83_RS10920	COG1160	GTP binding
CJO83_RS10930	COG2976	Protein conserved in bacteria
CJO83_RS10935	COG0124	histidyl-tRNA synthetase
CJO83_RS10940	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CJO83_RS10955	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CJO83_RS10960	COG0105	UTP biosynthetic process
CJO83_RS10970	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CJO83_RS10990	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CJO83_RS10995	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CJO83_RS11000	COG3321	synthase
CJO83_RS11000	COG1028	Short-chain dehydrogenase reductase Sdr
CJO83_RS11000	COG0604	alcohol dehydrogenase
CJO83_RS11005	COG1902	pentaerythritol trinitrate reductase activity
CJO83_RS11010	COG1309	transcriptional regulator
CJO83_RS11015	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CJO83_RS11025	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CJO83_RS11030	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CJO83_RS11045	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CJO83_RS11050	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CJO83_RS11055	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CJO83_RS11065	COG1074	ATP-dependent DNA helicase activity
CJO83_RS11080	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CJO83_RS11085	COG2204	response regulator
CJO83_RS11090	COG2197	response regulator
CJO83_RS11095	COG3228	Belongs to the MtfA family
CJO83_RS11105	COG0254	rRNA binding
CJO83_RS11115	COG0534	Mate efflux family protein
CJO83_RS11150	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CJO83_RS11155	COG1752	Esterase of the alpha-beta hydrolase superfamily
CJO83_RS11160	COG0791	NLP P60 protein
CJO83_RS11165	COG4172	Belongs to the ABC transporter superfamily
CJO83_RS11170	COG4239	(ABC) transporter, permease
CJO83_RS11175	COG4174	ABC transporter (Permease)
CJO83_RS11180	COG4166	transmembrane transport
CJO83_RS11195	COG0527	aspartate kinase activity
CJO83_RS11200	COG0037	tRNA processing
CJO83_RS11205	COG0825	malonyl-CoA metabolic process
CJO83_RS11210	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CJO83_RS11215	COG0215	cysteine-tRNA ligase activity
CJO83_RS11230	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CJO83_RS11235	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CJO83_RS11240	COG1045	serine acetyltransferase
CJO83_RS11250	COG0483	inositol monophosphate 1-phosphatase activity
CJO83_RS11255	COG1396	sequence-specific DNA binding
CJO83_RS11265	COG2258	MOSC domain
CJO83_RS11275	COG0840	transmembrane signaling receptor activity
CJO83_RS11285	COG2814	Major facilitator Superfamily
CJO83_RS11290	COG0583	DNA-binding transcription factor activity
CJO83_RS11295	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CJO83_RS11310	COG2850	peptidyl-arginine hydroxylation
CJO83_RS11315	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CJO83_RS11315	COG0321	lipoyl(octanoyl) transferase activity
CJO83_RS11320	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CJO83_RS11325	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CJO83_RS11335	COG0180	Tryptophanyl-tRNA synthetase
CJO83_RS11340	COG1994	Peptidase M50
CJO83_RS11345	COG0009	L-threonylcarbamoyladenylate synthase
CJO83_RS11350	COG0613	PHP domain protein
CJO83_RS11355	COG0492	ferredoxin-NADP+ reductase activity
CJO83_RS11370	COG3011	Protein conserved in bacteria
CJO83_RS11375	COG2267	carboxylic ester hydrolase activity
CJO83_RS11380	COG2833	Protein of unknown function (DUF455)
CJO83_RS11390	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CJO83_RS11400	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CJO83_RS11405	COG0148	phosphopyruvate hydratase activity
CJO83_RS11415	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CJO83_RS11420	COG0504	CTP synthase activity
CJO83_RS11445	COG2308	Evidence 4 Homologs of previously reported genes of
CJO83_RS11455	COG0084	hydrolase, TatD family'
CJO83_RS11460	COG1136	(ABC) transporter
CJO83_RS11475	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CJO83_RS11480	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CJO83_RS11505	COG2855	membrane
CJO83_RS11510	COG0583	DNA-binding transcription factor activity
CJO83_RS11580	COG0436	Aminotransferase
CJO83_RS11590	COG0583	DNA-binding transcription factor activity
CJO83_RS11595	COG2271	Major facilitator Superfamily
CJO83_RS11635	COG0625	glutathione transferase activity
CJO83_RS11640	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CJO83_RS11650	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CJO83_RS11660	COG2271	Major facilitator Superfamily
CJO83_RS11670	COG2186	Transcriptional regulator
CJO83_RS11675	COG3385	transposase activity
CJO83_RS11685	COG0745	RESPONSE REGULATOR receiver
CJO83_RS11695	COG5002	protein histidine kinase activity
CJO83_RS11705	COG0745	RESPONSE REGULATOR receiver
CJO83_RS11730	COG0322	excinuclease ABC activity
CJO83_RS11740	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CJO83_RS11750	COG0736	holo-[acyl-carrier-protein] synthase activity
CJO83_RS11755	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CJO83_RS11760	COG1381	Involved in DNA repair and RecF pathway recombination
CJO83_RS11765	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CJO83_RS11770	COG0571	ribonuclease III activity
CJO83_RS11780	COG0681	Belongs to the peptidase S26 family
CJO83_RS11785	COG0481	GTPase activity
CJO83_RS11795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CJO83_RS11820	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CJO83_RS11825	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CJO83_RS11830	COG1028	Short-chain dehydrogenase reductase Sdr
CJO83_RS11840	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CJO83_RS11845	COG0416	fatty acid biosynthetic process
CJO83_RS11850	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CJO83_RS11855	COG1399	metal-binding, possibly nucleic acid-binding protein
CJO83_RS11860	COG0424	maF-like protein
CJO83_RS11870	COG0616	signal peptide processing
CJO83_RS11870	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CJO83_RS11880	COG0546	phosphoglycolate phosphatase activity
CJO83_RS11890	COG1530	ribonuclease E activity
CJO83_RS11895	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CJO83_RS11900	COG0746	molybdenum cofactor guanylyltransferase activity
CJO83_RS11915	COG1322	Protein conserved in bacteria
CJO83_RS11935	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CJO83_RS11945	COG1028	Short-chain dehydrogenase reductase Sdr
CJO83_RS11950	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CJO83_RS11960	COG3385	transposase activity
CJO83_RS11975	COG0443	Heat shock 70 kDa protein
CJO83_RS11980	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CJO83_RS11990	COG0316	Belongs to the HesB IscA family
CJO83_RS11995	COG0822	iron-sulfur transferase activity
CJO83_RS12000	COG1104	cysteine desulfurase activity
CJO83_RS12010	COG1879	ABC-type sugar transport system periplasmic component
CJO83_RS12020	COG1172	Belongs to the binding-protein-dependent transport system permease family
CJO83_RS12025	COG1609	Transcriptional regulator
CJO83_RS12030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CJO83_RS12040	COG0556	nucleotide-excision repair
CJO83_RS12055	COG1309	transcriptional regulator
CJO83_RS12060	COG2878	Part of a membrane complex involved in electron transport
CJO83_RS12065	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CJO83_RS12070	COG0778	Nitroreductase
CJO83_RS12075	COG3039	Transposase
CJO83_RS12095	COG3385	transposase activity
CJO83_RS12110	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CJO83_RS12150	COG0326	Molecular chaperone. Has ATPase activity
CJO83_RS12155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CJO83_RS12160	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CJO83_RS12165	COG0697	spore germination
CJO83_RS12175	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CJO83_RS12180	COG0625	glutathione transferase activity
CJO83_RS12195	COG1620	l-lactate permease
CJO83_RS12215	COG0741	lytic transglycosylase activity
CJO83_RS12225	COG0488	(ABC) transporter
CJO83_RS12265	COG0513	Belongs to the DEAD box helicase family
CJO83_RS12270	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CJO83_RS12280	COG0861	Integral membrane protein TerC family
CJO83_RS12290	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CJO83_RS12295	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CJO83_RS12300	COG0312	modulator of DNA gyrase
CJO83_RS12305	COG3028	Belongs to the UPF0307 family
CJO83_RS12310	COG0521	Mo-molybdopterin cofactor biosynthetic process
CJO83_RS12315	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CJO83_RS12320	COG0501	Belongs to the peptidase M48B family
CJO83_RS12325	COG1162	GTPase activity
CJO83_RS12335	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CJO83_RS12340	COG0494	nUDIX hydrolase
CJO83_RS12345	COG0335	large ribosomal subunit rRNA binding
CJO83_RS12350	COG0336	Belongs to the RNA methyltransferase TrmD family
CJO83_RS12355	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CJO83_RS12360	COG0228	four-way junction DNA binding
CJO83_RS12395	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CJO83_RS12400	COG1960	acyl-CoA dehydrogenase activity
CJO83_RS12420	COG2011	ABC-type metal ion transport system permease component
CJO83_RS12425	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CJO83_RS12430	COG0123	including yeast histone deacetylase and acetoin utilization protein
CJO83_RS12435	COG2951	lytic endotransglycosylase activity
CJO83_RS12440	COG3385	transposase activity
CJO83_RS12455	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CJO83_RS12460	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CJO83_RS12470	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CJO83_RS12480	COG0776	regulation of translation
CJO83_RS12490	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CJO83_RS12495	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CJO83_RS12500	COG0287	Prephenate dehydrogenase
CJO83_RS12505	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CJO83_RS12510	COG1605	Chorismate mutase
CJO83_RS12510	COG0077	Prephenate dehydratase
CJO83_RS12515	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CJO83_RS12540	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CJO83_RS12600	COG3039	Transposase
CJO83_RS12680	COG3039	Transposase
CJO83_RS12850	COG1309	transcriptional regulator
CJO83_RS12855	COG1028	Short-chain dehydrogenase reductase Sdr
CJO83_RS12860	COG0604	alcohol dehydrogenase
CJO83_RS12895	COG0778	Nitroreductase
CJO83_RS12910	COG4305	rare lipoprotein A
CJO83_RS12940	COG1280	lysine exporter protein (LysE YggA)
CJO83_RS12955	COG0425	Belongs to the sulfur carrier protein TusA family
CJO83_RS12970	COG1942	4-Oxalocrotonate Tautomerase
CJO83_RS12975	COG0235	Class ii aldolase
CJO83_RS12980	COG0477	Major facilitator Superfamily
CJO83_RS12995	COG0330	HflC and HflK could
CJO83_RS13020	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CJO83_RS13025	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CJO83_RS13050	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CJO83_RS13080	COG4681	YaeQ
CJO83_RS13095	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CJO83_RS13105	COG0318	PFAM AMP-dependent synthetase and ligase
CJO83_RS13110	COG3118	belongs to the thioredoxin family
CJO83_RS13120	COG2703	oxygen carrier activity
CJO83_RS13125	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CJO83_RS13130	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CJO83_RS13135	COG2982	Protein involved in outer membrane biogenesis
CJO83_RS13160	COG0259	pyridoxamine-phosphate oxidase activity
CJO83_RS13165	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CJO83_RS13175	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CJO83_RS13180	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CJO83_RS13190	COG1522	sequence-specific DNA binding
CJO83_RS13195	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CJO83_RS13205	COG3483	tryptophan 2,3-dioxygenase activity
CJO83_RS13215	COG1960	acyl-CoA dehydrogenase activity
CJO83_RS13220	COG2252	PERMEase
CJO83_RS13225	COG0450	alkyl hydroperoxide reductase
CJO83_RS13230	COG4575	ribosome binding
CJO83_RS13250	COG1136	(ABC) transporter
CJO83_RS13255	COG0390	transport system, permease component
CJO83_RS13280	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CJO83_RS13285	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CJO83_RS13290	COG0745	RESPONSE REGULATOR receiver
CJO83_RS13300	COG3385	transposase activity
CJO83_RS13310	COG2391	methyltransferase activity
CJO83_RS13315	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CJO83_RS13330	COG0823	Involved in the tonB-independent uptake of proteins
CJO83_RS13350	COG0824	Thioesterase
CJO83_RS13355	COG4221	oxidoreductase activity
CJO83_RS13360	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CJO83_RS13365	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CJO83_RS13430	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CJO83_RS13430	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CJO83_RS13445	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CJO83_RS13450	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CJO83_RS13455	COG0436	Aminotransferase
CJO83_RS13465	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CJO83_RS13495	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CJO83_RS13500	COG1902	pentaerythritol trinitrate reductase activity
CJO83_RS13505	COG1968	undecaprenyl-diphosphatase activity
CJO83_RS13530	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CJO83_RS13535	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CJO83_RS13535	COG0425	Belongs to the sulfur carrier protein TusA family
CJO83_RS13555	COG0859	PFAM glycosyl transferase family 9
CJO83_RS13570	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CJO83_RS13605	COG1088	dTDP-glucose 4,6-dehydratase activity
CJO83_RS13610	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CJO83_RS13625	COG0540	Belongs to the ATCase OTCase family
CJO83_RS13630	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CJO83_RS13635	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CJO83_RS13640	COG1678	Uncharacterized ACR, COG1678
CJO83_RS13645	COG1187	pseudouridine synthase activity
CJO83_RS13655	COG0643	Histidine kinase
CJO83_RS13655	COG0784	Response regulator, receiver
CJO83_RS13655	COG2198	Histidine kinase
CJO83_RS13660	COG0840	transmembrane signaling receptor activity
CJO83_RS13680	COG1773	rubredoxin
CJO83_RS13685	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CJO83_RS13690	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CJO83_RS13700	COG1704	LemA family
CJO83_RS13745	COG4964	Belongs to the GSP D family
CJO83_RS13810	COG4269	membrane
CJO83_RS13815	COG0459	protein refolding
CJO83_RS13820	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CJO83_RS13840	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CJO83_RS13845	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
CJO83_RS13855	COG2974	May be involved in recombination
CJO83_RS13885	COG0697	spore germination
CJO83_RS13925	COG0840	transmembrane signaling receptor activity
CJO83_RS13930	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CJO83_RS13950	COG2995	paraquat-inducible protein a
CJO83_RS13955	COG3008	intermembrane lipid transfer
CJO83_RS13955	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CJO83_RS13965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CJO83_RS14030	COG0738	Major facilitator superfamily
CJO83_RS14035	COG2027	D-alanyl-D-alanine carboxypeptidase
CJO83_RS14040	COG1763	Mo-molybdopterin cofactor biosynthetic process
CJO83_RS14060	COG0546	phosphoglycolate phosphatase activity
CJO83_RS14070	COG0009	L-threonylcarbamoyladenylate synthase
CJO83_RS14075	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CJO83_RS14080	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CJO83_RS14085	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CJO83_RS14095	COG0469	pyruvate kinase activity
CJO83_RS14100	COG0126	phosphoglycerate kinase activity
CJO83_RS14130	COG0859	PFAM glycosyl transferase family 9
CJO83_RS14140	COG0429	hydrolase of the alpha beta-hydrolase fold
CJO83_RS14150	COG4783	chaperone-mediated protein folding
CJO83_RS14155	COG0315	cyclic pyranopterin monophosphate synthase activity
CJO83_RS14165	COG4969	Belongs to the N-Me-Phe pilin family
CJO83_RS14175	COG0861	Integral membrane protein TerC family
CJO83_RS14185	COG0045	succinate-CoA ligase (ADP-forming) activity
CJO83_RS14195	COG2137	regulation of response to DNA damage stimulus
CJO83_RS14200	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CJO83_RS14210	COG0642	Histidine kinase
CJO83_RS14220	COG0477	Major facilitator Superfamily
CJO83_RS14330	COG0513	Belongs to the DEAD box helicase family
CJO83_RS14360	COG0318	PFAM AMP-dependent synthetase and ligase
CJO83_RS14385	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CJO83_RS14390	COG1702	phosphate starvation-inducible protein PhoH
CJO83_RS14395	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CJO83_RS14400	COG4535	Mg2 and Co2 transporter CorC
CJO83_RS14405	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CJO83_RS14410	COG0752	glycyl-tRNA synthetase alpha subunit
CJO83_RS14420	COG0751	glycine-tRNA ligase activity
CJO83_RS14425	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CJO83_RS14430	COG0204	Acyl-transferase
CJO83_RS14445	COG0346	lactoylglutathione lyase activity
CJO83_RS14450	COG0697	spore germination
CJO83_RS14455	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CJO83_RS14460	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CJO83_RS14465	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CJO83_RS14470	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CJO83_RS14490	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CJO83_RS14500	COG0006	proline dipeptidase activity
CJO83_RS14505	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CJO83_RS14515	COG4680	protein conserved in bacteria
CJO83_RS14530	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CJO83_RS14535	COG0138	bifunctional purine biosynthesis protein purh
CJO83_RS14540	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CJO83_RS14550	COG0632	four-way junction helicase activity
CJO83_RS14555	COG2255	four-way junction helicase activity
CJO83_RS14570	COG1490	D-aminoacyl-tRNA deacylase activity
CJO83_RS14575	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CJO83_RS14580	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CJO83_RS14585	COG0316	Belongs to the HesB IscA family
CJO83_RS14600	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CJO83_RS14605	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CJO83_RS14625	COG0418	dihydroorotase activity
CJO83_RS14635	COG0473	3-isopropylmalate dehydrogenase activity
CJO83_RS14640	COG0121	glutamine amidotransferase
CJO83_RS14645	COG1126	abc transporter atp-binding protein
CJO83_RS14650	COG0765	amino acid transport
CJO83_RS14655	COG0765	amino acid transport
CJO83_RS14665	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CJO83_RS14675	COG5265	(ABC) transporter
CJO83_RS14685	COG1024	Enoyl-CoA hydratase
CJO83_RS14690	COG0183	Belongs to the thiolase family
CJO83_RS14695	COG1250	3-hydroxyacyl-CoA dehydrogenase
CJO83_RS14695	COG1024	Enoyl-CoA hydratase
CJO83_RS14700	COG1960	acyl-CoA dehydrogenase activity
CJO83_RS14715	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CJO83_RS14720	COG3568	Endonuclease Exonuclease Phosphatase
CJO83_RS14725	COG0494	nUDIX hydrolase
CJO83_RS14735	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CJO83_RS14760	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CJO83_RS14775	COG2226	methyltransferase
CJO83_RS14785	COG4178	(ABC) transporter
CJO83_RS14800	COG1238	metal cluster binding
CJO83_RS14805	COG0700	Nucleoside recognition
CJO83_RS14820	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CJO83_RS14825	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CJO83_RS14825	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CJO83_RS14855	COG0318	PFAM AMP-dependent synthetase and ligase
CJO83_RS14860	COG3265	gluconokinase activity
CJO83_RS14875	COG2391	methyltransferase activity
CJO83_RS14890	COG1028	Short-chain dehydrogenase reductase Sdr
CJO83_RS14905	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CJO83_RS14930	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CJO83_RS14960	COG0629	single-stranded DNA binding
CJO83_RS14965	COG2814	Major facilitator Superfamily
CJO83_RS14980	COG1280	lysine exporter protein (LysE YggA)
CJO83_RS14985	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CJO83_RS14990	COG0693	protein deglycase activity
CJO83_RS15015	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CJO83_RS15030	COG1137	ATPase activity
CJO83_RS15035	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CJO83_RS15040	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CJO83_RS15050	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CJO83_RS15060	COG1660	Displays ATPase and GTPase activities
CJO83_RS15070	COG1194	a g-specific adenine glycosylase
CJO83_RS15080	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CJO83_RS15090	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CJO83_RS15095	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CJO83_RS15105	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CJO83_RS15110	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CJO83_RS15115	COG0193	aminoacyl-tRNA hydrolase activity
CJO83_RS15125	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CJO83_RS15130	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CJO83_RS15135	COG0742	ribosomal rna small subunit methyltransferase
CJO83_RS15140	COG0612	Peptidase, M16
CJO83_RS15145	COG0612	Peptidase, M16
CJO83_RS15160	COG0625	glutathione transferase activity
CJO83_RS15170	COG3707	response regulator
CJO83_RS15180	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CJO83_RS15185	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CJO83_RS15190	COG1116	anion transmembrane transporter activity
CJO83_RS15195	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CJO83_RS15200	COG1741	Belongs to the pirin family
CJO83_RS15210	COG5001	Diguanylate cyclase
CJO83_RS15210	COG3300	MHYT domain
CJO83_RS15215	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CJO83_RS15220	COG1999	signal sequence binding
CJO83_RS15225	COG0109	protoheme IX farnesyltransferase activity
CJO83_RS15230	COG1612	heme a metabolic process
CJO83_RS15260	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
CJO83_RS15265	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CJO83_RS15280	COG2226	methyltransferase
CJO83_RS15285	COG1040	competence protein
CJO83_RS15295	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CJO83_RS15300	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CJO83_RS15305	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CJO83_RS15310	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CJO83_RS15315	COG0588	phosphoglycerate mutase activity
CJO83_RS15320	COG0793	Belongs to the peptidase S41A family
CJO83_RS15340	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CJO83_RS15345	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CJO83_RS15355	COG0189	ligase activity
CJO83_RS15365	COG0004	ammonium transporteR
CJO83_RS15395	COG3039	Transposase
CJO83_RS15435	COG3039	Transposase
CJO83_RS15535	COG3039	Transposase
CJO83_RS15560	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CJO83_RS15570	COG2204	response regulator
CJO83_RS15575	COG4191	Histidine kinase
CJO83_RS15580	COG1301	dicarboxylic acid transport
CJO83_RS15585	COG3411	Ferredoxin
CJO83_RS15595	COG1686	Belongs to the peptidase S11 family
CJO83_RS15600	COG2921	Belongs to the UPF0250 family
CJO83_RS15605	COG0583	DNA-binding transcription factor activity
CJO83_RS15615	COG0321	lipoyl(octanoyl) transferase activity
CJO83_RS15620	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CJO83_RS15665	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CJO83_RS15670	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CJO83_RS15670	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CJO83_RS15675	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CJO83_RS15685	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CJO83_RS15710	COG1024	Enoyl-CoA hydratase
CJO83_RS15740	COG2267	carboxylic ester hydrolase activity
CJO83_RS15760	COG1410	methionine synthase
CJO83_RS15760	COG0646	methionine synthase
CJO83_RS15765	COG3039	Transposase
CJO83_RS15775	COG2197	response regulator
CJO83_RS15800	COG0018	arginyl-trna synthetase
CJO83_RS15810	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CJO83_RS15815	COG4221	oxidoreductase activity
CJO83_RS15860	COG2329	Antibiotic biosynthesis monooxygenase
CJO83_RS15870	COG0789	Transcriptional regulator
CJO83_RS15875	COG1960	acyl-CoA dehydrogenase activity
CJO83_RS15880	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
CJO83_RS15885	COG0288	reversible hydration of carbon dioxide
CJO83_RS15890	COG0183	Belongs to the thiolase family
CJO83_RS15895	COG1028	Short-chain dehydrogenase reductase Sdr
CJO83_RS15900	COG1960	acyl-CoA dehydrogenase activity
CJO83_RS15915	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CJO83_RS15920	COG3012	SEC-C Motif Domain Protein
CJO83_RS15925	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CJO83_RS15935	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CJO83_RS15940	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CJO83_RS15945	COG4770	biotin carboxylase activity
CJO83_RS15960	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CJO83_RS15990	COG0596	Alpha beta hydrolase
CJO83_RS16025	COG3039	Transposase
CJO83_RS16035	COG1250	3-hydroxyacyl-CoA dehydrogenase
CJO83_RS16040	COG0583	DNA-binding transcription factor activity
CJO83_RS16075	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CJO83_RS16075	COG1703	isobutyryl-CoA mutase activity
CJO83_RS16075	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CJO83_RS16120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CJO83_RS16130	COG0430	RNA-3'-phosphate cyclase activity
CJO83_RS16135	COG3541	Predicted nucleotidyltransferase
CJO83_RS16140	COG1690	Belongs to the RtcB family
CJO83_RS16150	COG4650	regulator
CJO83_RS16165	COG1254	Belongs to the acylphosphatase family
CJO83_RS16185	COG2814	Major facilitator Superfamily
CJO83_RS16190	COG1028	Short-chain dehydrogenase reductase Sdr
CJO83_RS16195	COG0583	DNA-binding transcription factor activity
CJO83_RS16200	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CJO83_RS16200	COG0519	Catalyzes the synthesis of GMP from XMP
CJO83_RS16215	COG1733	regulation of RNA biosynthetic process
CJO83_RS16255	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CJO83_RS16265	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CJO83_RS16270	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CJO83_RS16275	COG0071	Belongs to the small heat shock protein (HSP20) family
CJO83_RS16290	COG3038	cytochrome b561
CJO83_RS16310	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CJO83_RS16315	COG1063	alcohol dehydrogenase
CJO83_RS16325	COG2197	response regulator
CJO83_RS16330	COG3851	Histidine kinase
CJO83_RS16335	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CJO83_RS16370	COG3039	Transposase
CJO83_RS16375	COG0589	response to stress
CJO83_RS16380	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CJO83_RS16400	COG0589	response to stress
CJO83_RS16410	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CJO83_RS16415	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CJO83_RS16425	COG0037	tRNA processing
CJO83_RS16430	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CJO83_RS16435	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CJO83_RS16435	COG0546	phosphoglycolate phosphatase activity
CJO83_RS16460	COG0493	'glutamate synthase
CJO83_RS16475	COG0842	Transport permease protein
CJO83_RS16480	COG1131	(ABC) transporter
CJO83_RS16495	COG1012	belongs to the aldehyde dehydrogenase family
CJO83_RS16500	COG0583	DNA-binding transcription factor activity
CJO83_RS16505	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CJO83_RS16530	COG2223	nitrite transmembrane transporter activity
CJO83_RS16545	COG0697	spore germination
CJO83_RS16570	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CJO83_RS16590	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CJO83_RS16595	COG4682	membrane
CJO83_RS16600	COG0708	Exodeoxyribonuclease III
CJO83_RS16605	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CJO83_RS16610	COG2326	polyphosphate kinase activity
CJO83_RS16615	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CJO83_RS16620	COG1560	Kdo2-lipid A biosynthetic process
CJO83_RS16630	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CJO83_RS16650	COG0517	IMP dehydrogenase activity
CJO83_RS16660	COG1522	sequence-specific DNA binding
CJO83_RS16705	COG1960	acyl-CoA dehydrogenase activity
CJO83_RS16740	COG2070	2-Nitropropane dioxygenase
CJO83_RS16745	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CJO83_RS16760	COG2022	thiamine diphosphate biosynthetic process
CJO83_RS16770	COG2764	glyoxalase bleomycin resistance protein dioxygenase
CJO83_RS16810	COG0351	phosphomethylpyrimidine kinase
CJO83_RS16820	COG1785	Belongs to the alkaline phosphatase family
CJO83_RS16825	COG1785	Belongs to the alkaline phosphatase family
CJO83_RS16840	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CJO83_RS16845	COG1950	PFAM Membrane protein of
CJO83_RS16850	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CJO83_RS16860	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CJO83_RS16880	COG0617	tRNA 3'-terminal CCA addition
CJO83_RS16890	COG3246	L-lysine catabolic process to acetate
CJO83_RS16895	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CJO83_RS16920	COG2204	response regulator
CJO83_RS16925	COG5000	phosphorelay sensor kinase activity
CJO83_RS16940	COG0501	Belongs to the peptidase M48B family
CJO83_RS16950	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CJO83_RS16960	COG0242	peptide deformylase activity
CJO83_RS16965	COG1652	LysM domain
CJO83_RS16970	COG0758	DNA mediated transformation
CJO83_RS16985	COG0583	DNA-binding transcription factor activity
CJO83_RS16990	COG0318	PFAM AMP-dependent synthetase and ligase
CJO83_RS16995	COG0772	Belongs to the SEDS family
CJO83_RS17000	COG0768	penicillin binding
CJO83_RS17010	COG1792	Involved in formation and maintenance of cell shape
CJO83_RS17015	COG1077	Cell shape determining protein MreB Mrl
CJO83_RS17020	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CJO83_RS17025	COG0154	amidase activity
CJO83_RS17040	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CJO83_RS17050	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CJO83_RS17055	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CJO83_RS17075	COG0523	cobalamin synthesis protein
CJO83_RS17090	COG0747	negative chemotaxis
CJO83_RS17095	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CJO83_RS17100	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CJO83_RS17110	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CJO83_RS17140	COG1595	DNA-templated transcription, initiation
CJO83_RS17145	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CJO83_RS17160	COG3385	transposase activity
CJO83_RS17170	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CJO83_RS17180	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CJO83_RS17200	COG2879	small protein
CJO83_RS17205	COG1966	Carbon starvation protein
CJO83_RS17220	COG3622	Belongs to the hyi family
CJO83_RS17230	COG0745	RESPONSE REGULATOR receiver
CJO83_RS17235	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CJO83_RS17245	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CJO83_RS17250	COG3384	dioxygenase
CJO83_RS17265	COG1309	transcriptional regulator
CJO83_RS17270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CJO83_RS17275	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CJO83_RS17285	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CJO83_RS17300	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CJO83_RS17305	COG0706	membrane insertase activity
CJO83_RS17310	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CJO83_RS17315	COG0594	ribonuclease P activity
CJO83_RS17320	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CJO83_RS17330	COG3385	transposase activity
CJO83_RS17335	COG1278	Cold shock
CJO83_RS17360	COG0477	Major facilitator Superfamily
CJO83_RS17365	COG4191	Histidine kinase
CJO83_RS17375	COG4377	Putative membrane peptidase family (DUF2324)
CJO83_RS17385	COG5002	protein histidine kinase activity
CJO83_RS17385	COG5001	Diguanylate cyclase
CJO83_RS17385	COG3447	MASE1 domain protein
CJO83_RS17425	COG0038	chloride channel
CJO83_RS17440	COG1881	PFAM PEBP family protein
CJO83_RS17470	COG2916	Histone family protein nucleoid-structuring protein H-NS
CJO83_RS17475	COG3039	Transposase
CJO83_RS17500	COG1028	Short-chain dehydrogenase reductase Sdr
CJO83_RS17510	COG1024	Enoyl-CoA hydratase
CJO83_RS17515	COG1960	acyl-CoA dehydrogenase activity
CJO83_RS17555	COG3039	Transposase
CJO83_RS17575	COG3039	Transposase
CJO83_RS17590	COG0477	Major facilitator Superfamily
CJO83_RS17595	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CJO83_RS17600	COG3657	addiction module killer protein
CJO83_RS17605	COG2814	Major facilitator Superfamily
CJO83_RS17645	COG0725	ABC transporter, periplasmic molybdate-binding protein
CJO83_RS17660	COG0714	Associated with various cellular activities
CJO83_RS17675	COG0288	reversible hydration of carbon dioxide
CJO83_RS17680	COG0659	secondary active sulfate transmembrane transporter activity
CJO83_RS17725	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CJO83_RS17735	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
CJO83_RS17740	COG2944	sequence-specific DNA binding
CJO83_RS17755	COG3039	Transposase
CJO83_RS17765	COG0210	DNA helicase
CJO83_RS17785	COG3039	Transposase
CJO83_RS17795	COG0697	spore germination
CJO83_RS17810	COG0446	pyridine nucleotide-disulphide oxidoreductase
CJO83_RS17810	COG1902	pentaerythritol trinitrate reductase activity
CJO83_RS17820	COG4677	pectinesterase activity
CJO83_RS17835	COG4968	Prepilin-type N-terminal cleavage methylation domain
CJO83_RS17850	COG4796	Type ii and iii secretion system protein
CJO83_RS17875	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CJO83_RS17905	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CJO83_RS17915	COG0534	Mate efflux family protein
CJO83_RS17920	COG3251	PFAM MbtH domain protein
CJO83_RS17930	COG0529	Catalyzes the synthesis of activated sulfate
CJO83_RS17965	COG1104	cysteine desulfurase activity
CJO83_RS18030	COG2706	6-phosphogluconolactonase activity
CJO83_RS18060	COG0730	response to heat
CJO83_RS18095	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CJO83_RS18105	COG0028	Belongs to the TPP enzyme family
CJO83_RS18120	COG1607	acyl-coa hydrolase
CJO83_RS18160	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CJO83_RS18175	COG3039	Transposase
CJO83_RS18190	COG3039	Transposase
CJO83_RS18240	COG1846	Transcriptional regulator
CJO83_RS18245	COG1024	Enoyl-CoA hydratase
CJO83_RS18250	COG1012	belongs to the aldehyde dehydrogenase family
CJO83_RS18280	COG0657	acetylesterase activity
CJO83_RS18290	COG2814	Major facilitator Superfamily
CJO83_RS18300	COG1640	4-alpha-glucanotransferase
CJO83_RS18305	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CJO83_RS18320	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CJO83_RS18325	COG0366	Alpha amylase catalytic
CJO83_RS18330	COG0366	Alpha amylase catalytic
CJO83_RS18335	COG0297	glycogen (starch) synthase activity
CJO83_RS18340	COG3720	iron ion transport
CJO83_RS18345	COG4771	TonB-dependent receptor
CJO83_RS18355	COG3634	alkyl hydroperoxide reductase activity
CJO83_RS18360	COG0735	belongs to the Fur family
CJO83_RS18380	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CJO83_RS18380	COG1918	ferrous iron import across plasma membrane
CJO83_RS18390	COG5001	Diguanylate cyclase
CJO83_RS18390	COG5002	protein histidine kinase activity
CJO83_RS18390	COG3447	MASE1 domain protein
CJO83_RS18400	COG0840	transmembrane signaling receptor activity
CJO83_RS18420	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CJO83_RS18435	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CJO83_RS18445	COG0456	acetyltransferase
CJO83_RS18445	COG0454	-acetyltransferase
CJO83_RS18490	COG3039	Transposase
CJO83_RS18525	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
CJO83_RS18540	COG3706	GGDEF domain
CJO83_RS18545	COG0531	amino acid
CJO83_RS18550	COG0534	Mate efflux family protein
CJO83_RS18565	COG2197	response regulator
CJO83_RS18575	COG0726	polysaccharide deacetylase
CJO83_RS18575	COG1649	PFAM Uncharacterised BCR, COG1649
CJO83_RS18580	COG1215	transferase activity, transferring glycosyl groups
CJO83_RS18595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CJO83_RS18600	COG2274	protein secretion by the type I secretion system
CJO83_RS18635	COG3039	Transposase
CJO83_RS18640	COG0840	transmembrane signaling receptor activity
CJO83_RS18650	COG1028	Short-chain dehydrogenase reductase Sdr
CJO83_RS18660	COG2070	2-Nitropropane dioxygenase
CJO83_RS18665	COG0583	DNA-binding transcription factor activity
CJO83_RS18670	COG1695	Transcriptional regulator
CJO83_RS18685	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CJO83_RS18690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CJO83_RS18695	COG0745	RESPONSE REGULATOR receiver
CJO83_RS18700	COG5002	protein histidine kinase activity
CJO83_RS18700	COG3850	Histidine kinase
CJO83_RS18715	COG0589	response to stress
CJO83_RS18740	COG0789	Transcriptional regulator
CJO83_RS18750	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CJO83_RS18775	COG1764	response to oxidative stress
CJO83_RS18790	COG0473	3-isopropylmalate dehydrogenase activity
CJO83_RS18825	COG2916	Histone family protein nucleoid-structuring protein H-NS
CJO83_RS18835	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CJO83_RS18845	COG3039	Transposase
CJO83_RS18870	COG1815	bacterial-type flagellum-dependent cell motility
CJO83_RS18880	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CJO83_RS18885	COG1749	Flagellar hook protein flgE
CJO83_RS18890	COG4787	bacterial-type flagellum-dependent cell motility
CJO83_RS18900	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CJO83_RS18935	COG2226	methyltransferase
CJO83_RS18950	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CJO83_RS18955	COG1028	Short-chain dehydrogenase reductase Sdr
CJO83_RS18965	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CJO83_RS18985	COG2986	histidine ammonia-lyase
CJO83_RS18995	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CJO83_RS19005	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CJO83_RS19015	COG0204	Acyl-transferase
CJO83_RS19030	COG1987	bacterial-type flagellum assembly
CJO83_RS19035	COG1338	Plays a role in the flagellum-specific transport system
CJO83_RS19065	COG2197	response regulator
CJO83_RS19095	COG1846	Transcriptional regulator
CJO83_RS19110	COG1677	Flagellar hook-basal body complex protein FliE
CJO83_RS19120	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CJO83_RS19155	COG4251	negative regulation of phosphorylation
CJO83_RS19155	COG3706	GGDEF domain
CJO83_RS19155	COG2203	Gaf domain
CJO83_RS19155	COG5001	Diguanylate cyclase
CJO83_RS19165	COG5001	Diguanylate cyclase
CJO83_RS19165	COG3706	GGDEF domain
CJO83_RS19165	COG2203	Gaf domain
CJO83_RS19165	COG4251	negative regulation of phosphorylation
CJO83_RS19185	COG3385	transposase activity
CJO83_RS19205	COG0318	PFAM AMP-dependent synthetase and ligase
CJO83_RS19255	COG2223	nitrite transmembrane transporter activity
CJO83_RS19280	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CJO83_RS19285	COG2423	ornithine cyclodeaminase activity
CJO83_RS19290	COG4264	IucA IucC family
CJO83_RS19295	COG2814	Major facilitator Superfamily
CJO83_RS19300	COG4264	IucA IucC family
CJO83_RS19305	COG4264	IucA IucC family
CJO83_RS19315	COG0019	diaminopimelate decarboxylase activity
CJO83_RS19360	COG1902	pentaerythritol trinitrate reductase activity
CJO83_RS19370	COG0583	DNA-binding transcription factor activity
CJO83_RS19375	COG1126	abc transporter atp-binding protein
CJO83_RS19380	COG0765	amino acid transport
CJO83_RS19385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CJO83_RS19390	COG1522	sequence-specific DNA binding
CJO83_RS19395	COG2423	ornithine cyclodeaminase activity
CJO83_RS19420	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CJO83_RS19455	COG0537	adenosine 5'-monophosphoramidase activity
CJO83_RS19460	COG0786	glutamate:sodium symporter activity
CJO83_RS19500	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CJO83_RS19510	COG0840	transmembrane signaling receptor activity
CJO83_RS19525	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CJO83_RS19545	COG0668	transmembrane transport
CJO83_RS19580	COG3706	GGDEF domain
CJO83_RS19585	COG1914	H( )-stimulated, divalent metal cation uptake system
CJO83_RS19615	COG2910	NAD(P)H-binding
CJO83_RS19660	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CJO83_RS19700	COG3039	Transposase
CJO83_RS19730	COG3039	Transposase
CJO83_RS19775	COG1858	cytochrome C peroxidase
CJO83_RS19780	COG1730	sister chromatid segregation
CJO83_RS19805	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
CJO83_RS19825	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CJO83_RS19965	COG1649	PFAM Uncharacterised BCR, COG1649
CJO83_RS20065	COG2197	response regulator
CJO83_RS20070	COG3916	Acyl-homoserine-lactone synthase
CJO83_RS20085	COG0525	valine-tRNA ligase activity
CJO83_RS20110	COG0318	PFAM AMP-dependent synthetase and ligase
CJO83_RS20115	COG2192	nodulation
CJO83_RS20130	COG0300	oxidoreductase activity
CJO83_RS20130	COG0318	PFAM AMP-dependent synthetase and ligase
CJO83_RS20130	COG3321	synthase
CJO83_RS20130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CJO83_RS20130	COG1028	Short-chain dehydrogenase reductase Sdr
CJO83_RS20145	COG0436	Aminotransferase
CJO83_RS20160	COG2814	Major facilitator Superfamily
CJO83_RS20175	COG0587	DNA-directed DNA polymerase activity
CJO83_RS20180	COG3620	sequence-specific DNA binding
CJO83_RS20185	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CJO83_RS20195	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CJO83_RS20210	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CJO83_RS20225	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CJO83_RS20230	COG4206	TonB-dependent receptor
CJO83_RS20245	COG0579	oxidoreductase
CJO83_RS20255	COG1309	transcriptional regulator
CJO83_RS20265	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CJO83_RS20290	COG0583	DNA-binding transcription factor activity
CJO83_RS20300	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CJO83_RS20305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CJO83_RS20315	COG2271	Major facilitator Superfamily
CJO83_RS20325	COG2721	sulfolactate sulfo-lyase activity
CJO83_RS20330	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CJO83_RS20345	COG2271	Major facilitator Superfamily
CJO83_RS20350	COG1051	belongs to the nudix hydrolase family
CJO83_RS20350	COG1056	cytidyltransferase-related domain
CJO83_RS20375	COG0840	transmembrane signaling receptor activity
CJO83_RS20425	COG1595	DNA-templated transcription, initiation
CJO83_RS20435	COG2197	response regulator
CJO83_RS20440	COG0745	RESPONSE REGULATOR receiver
CJO83_RS20480	COG4790	Type iii secretion
CJO83_RS20495	COG4789	Type iii secretion
CJO83_RS20500	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CJO83_RS20545	COG2207	Transcriptional regulator
CJO83_RS20550	COG1450	Type ii and iii secretion system protein
CJO83_RS20580	COG5434	Belongs to the glycosyl hydrolase 28 family
CJO83_RS20600	COG1674	ftsk spoiiie
CJO83_RS20645	COG1942	4-Oxalocrotonate Tautomerase
CJO83_RS20650	COG4569	acetaldehyde dehydrogenase (acetylating) activity
CJO83_RS20655	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CJO83_RS20660	COG2271	Major facilitator Superfamily
CJO83_RS20670	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CJO83_RS20690	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CJO83_RS20715	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CJO83_RS20720	COG0583	DNA-binding transcription factor activity
CJO83_RS20740	COG1309	transcriptional regulator
CJO83_RS20750	COG3039	Transposase
CJO83_RS20760	COG2853	Lipoprotein
CJO83_RS20765	COG0745	RESPONSE REGULATOR receiver
CJO83_RS20775	COG2801	Transposase and inactivated derivatives
CJO83_RS20785	COG3039	Transposase
CJO83_RS20870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CJO83_RS20890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CJO83_RS20895	COG1126	abc transporter atp-binding protein
CJO83_RS20900	COG0765	amino acid transport
CJO83_RS20905	COG0765	amino acid transport
CJO83_RS20910	COG4221	oxidoreductase activity
CJO83_RS20915	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CJO83_RS20925	COG1984	allophanate hydrolase subunit 2
CJO83_RS20930	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CJO83_RS20940	COG0511	ligase activity, forming carbon-carbon bonds
CJO83_RS20950	COG0436	Aminotransferase
CJO83_RS20955	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CJO83_RS20965	COG3265	gluconokinase activity
CJO83_RS20970	COG1028	Short-chain dehydrogenase reductase Sdr
CJO83_RS20975	COG1063	alcohol dehydrogenase
CJO83_RS20995	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CJO83_RS21035	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
CJO83_RS21040	COG3604	Transcriptional regulator
CJO83_RS21045	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CJO83_RS21055	COG1396	sequence-specific DNA binding
CJO83_RS21085	COG3154	lipid carrier protein
CJO83_RS21090	COG0826	peptidase U32
CJO83_RS21095	COG0826	peptidase U32
CJO83_RS21110	COG2223	nitrite transmembrane transporter activity
CJO83_RS21115	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CJO83_RS21120	COG1140	nitrate reductase beta subunit
CJO83_RS21125	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CJO83_RS21130	COG2181	nitrate reductase activity
CJO83_RS21135	COG1763	Mo-molybdopterin cofactor biosynthetic process
CJO83_RS21140	COG3850	Histidine kinase
CJO83_RS21145	COG2197	response regulator
CJO83_RS21165	COG0352	thiamine-phosphate diphosphorylase activity
CJO83_RS21170	COG0477	Major facilitator Superfamily
CJO83_RS21175	COG1454	alcohol dehydrogenase
CJO83_RS21190	COG1999	signal sequence binding
CJO83_RS21210	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CJO83_RS21215	COG1301	dicarboxylic acid transport
CJO83_RS21225	COG0583	DNA-binding transcription factor activity
CJO83_RS21265	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CJO83_RS21275	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CJO83_RS21295	COG0110	maltose O-acetyltransferase activity
CJO83_RS21310	COG2244	polysaccharide biosynthetic process
CJO83_RS21315	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CJO83_RS21320	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CJO83_RS21325	COG0489	protein tyrosine kinase activity
CJO83_RS21325	COG3206	protein involved in exopolysaccharide biosynthesis
CJO83_RS21330	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CJO83_RS21335	COG1596	polysaccharide export
CJO83_RS21380	COG0840	transmembrane signaling receptor activity
CJO83_RS21420	COG3220	belongs to the UPF0276 family
CJO83_RS21455	COG0745	RESPONSE REGULATOR receiver
CJO83_RS21480	COG2223	nitrite transmembrane transporter activity
CJO83_RS21485	COG0243	molybdopterin cofactor binding
CJO83_RS21495	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CJO83_RS21500	COG5001	Diguanylate cyclase
CJO83_RS21500	COG3300	MHYT domain
CJO83_RS21505	COG3158	transport of potassium into the cell
CJO83_RS21510	COG1278	Cold shock
CJO83_RS21525	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CJO83_RS21535	COG4689	acetoacetate decarboxylase
CJO83_RS21540	COG1028	Short-chain dehydrogenase reductase Sdr
CJO83_RS21550	COG0673	inositol 2-dehydrogenase activity
CJO83_RS21580	COG3039	Transposase
CJO83_RS21605	COG3210	domain, Protein
CJO83_RS21615	COG2831	hemolysin activation secretion protein
CJO83_RS21625	COG0673	inositol 2-dehydrogenase activity
CJO83_RS21730	COG2197	response regulator
CJO83_RS21755	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CJO83_RS21760	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CJO83_RS21765	COG1877	trehalose-phosphatase activity
CJO83_RS21770	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CJO83_RS21775	COG1846	Transcriptional regulator
CJO83_RS21780	COG1764	response to oxidative stress
CJO83_RS21795	COG0583	DNA-binding transcription factor activity
CJO83_RS21805	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CJO83_RS21850	COG2030	dehydratase
CJO83_RS21870	COG3321	synthase
CJO83_RS21870	COG1028	Short-chain dehydrogenase reductase Sdr
CJO83_RS21870	COG0604	alcohol dehydrogenase
CJO83_RS21880	COG0583	DNA-binding transcription factor activity
CJO83_RS21890	COG1064	alcohol dehydrogenase
CJO83_RS21915	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
CJO83_RS21945	COG1064	alcohol dehydrogenase
CJO83_RS21955	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CJO83_RS21960	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CJO83_RS21965	COG0640	Transcriptional regulator
CJO83_RS21975	COG3039	Transposase
CJO83_RS22000	COG5444	nuclease activity
CJO83_RS22020	COG2197	response regulator
CJO83_RS22030	COG2066	Belongs to the glutaminase family
CJO83_RS22035	COG4149	molybdate abc transporter
CJO83_RS22040	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CJO83_RS22055	COG5001	Diguanylate cyclase
CJO83_RS22055	COG3300	MHYT domain
CJO83_RS22075	COG3813	Protein conserved in bacteria
CJO83_RS22095	COG0745	RESPONSE REGULATOR receiver
CJO83_RS22100	COG2205	protein histidine kinase activity
CJO83_RS22130	COG1858	cytochrome C peroxidase
CJO83_RS22150	COG1253	flavin adenine dinucleotide binding
CJO83_RS22155	COG1858	cytochrome C peroxidase
CJO83_RS22185	COG2205	protein histidine kinase activity
CJO83_RS22185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CJO83_RS22200	COG2274	protein secretion by the type I secretion system
CJO83_RS22225	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CJO83_RS22240	COG0800	Aldolase
CJO83_RS22245	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CJO83_RS22250	COG2197	response regulator
CJO83_RS22315	COG1294	oxidase, subunit
CJO83_RS22320	COG1271	oxidase subunit
CJO83_RS22325	COG5001	Diguanylate cyclase
CJO83_RS22325	COG3300	MHYT domain
CJO83_RS22330	COG0840	transmembrane signaling receptor activity
CJO83_RS22340	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CJO83_RS22355	COG0534	Mate efflux family protein
CJO83_RS22370	COG0243	molybdopterin cofactor binding
CJO83_RS22375	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CJO83_RS22385	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CJO83_RS22390	COG2223	nitrite transmembrane transporter activity
CJO83_RS22395	COG0840	transmembrane signaling receptor activity
CJO83_RS22400	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CJO83_RS22410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CJO83_RS22435	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CJO83_RS22440	COG0436	Aminotransferase
CJO83_RS22445	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CJO83_RS22445	COG0473	3-isopropylmalate dehydrogenase activity
CJO83_RS22475	COG3039	Transposase
CJO83_RS22485	COG2951	lytic endotransglycosylase activity
CJO83_RS22495	COG1271	oxidase subunit
CJO83_RS22500	COG1294	oxidase, subunit
CJO83_RS22505	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CJO83_RS22515	COG0251	oxidation-reduction process
CJO83_RS22550	COG3550	peptidyl-serine autophosphorylation
CJO83_RS22570	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CJO83_RS22590	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CJO83_RS22595	COG0730	response to heat
CJO83_RS22600	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CJO83_RS22615	COG0730	response to heat
CJO83_RS22645	COG0668	transmembrane transport
CJO83_RS22650	COG1742	UPF0060 membrane protein
CJO83_RS22670	COG0477	Major facilitator Superfamily
CJO83_RS22675	COG0114	fumarate hydratase activity
CJO83_RS22700	COG1621	beta-fructofuranosidase activity
CJO83_RS22710	COG1609	Transcriptional regulator
CJO83_RS22745	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CJO83_RS22765	COG3766	membrane
CJO83_RS22785	COG0683	leucine binding
CJO83_RS22810	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CJO83_RS22885	COG0840	transmembrane signaling receptor activity
CJO83_RS22890	COG0567	Dehydrogenase, E1 component
CJO83_RS22895	COG0204	Acyl-transferase
CJO83_RS22910	COG4263	nitrous-oxide reductase activity
CJO83_RS22960	COG2831	hemolysin activation secretion protein
CJO83_RS22995	COG2824	Alkylphosphonate utilization operon protein PhnA
CJO83_RS23005	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CJO83_RS23015	COG0762	integral membrane protein
CJO83_RS23040	COG1191	sigma factor activity
CJO83_RS23055	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CJO83_RS23065	COG1309	transcriptional regulator
CJO83_RS23070	COG2271	Major facilitator Superfamily
CJO83_RS23075	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CJO83_RS23080	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CJO83_RS23085	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CJO83_RS23095	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CJO83_RS23100	COG0745	RESPONSE REGULATOR receiver
CJO83_RS23105	COG2201	protein-glutamate methylesterase activity
CJO83_RS23110	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CJO83_RS23120	COG0840	transmembrane signaling receptor activity
CJO83_RS23125	COG0835	chemotaxis
CJO83_RS23135	COG0745	RESPONSE REGULATOR receiver
CJO83_RS23140	COG1360	Flagellar Motor Protein
CJO83_RS23175	COG0477	Major facilitator Superfamily
CJO83_RS23180	COG2267	carboxylic ester hydrolase activity
CJO83_RS23185	COG1028	Short-chain dehydrogenase reductase Sdr
CJO83_RS23185	COG3321	synthase
CJO83_RS23185	COG0300	oxidoreductase activity
CJO83_RS23185	COG0318	PFAM AMP-dependent synthetase and ligase
CJO83_RS23185	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CJO83_RS23195	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CJO83_RS23205	COG0644	oxidoreductase
CJO83_RS23210	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CJO83_RS23215	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CJO83_RS23245	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CJO83_RS23245	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CJO83_RS23280	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CJO83_RS23280	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CJO83_RS23285	COG1045	serine acetyltransferase
CJO83_RS23295	COG2205	protein histidine kinase activity
CJO83_RS23320	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CJO83_RS23330	COG0469	pyruvate kinase activity
CJO83_RS23340	COG0583	DNA-binding transcription factor activity
CJO83_RS23355	COG2205	protein histidine kinase activity
CJO83_RS23360	COG0745	RESPONSE REGULATOR receiver
CJO83_RS23370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CJO83_RS23380	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CJO83_RS23405	COG1136	(ABC) transporter
CJO83_RS23410	COG0577	efflux transmembrane transporter activity
CJO83_RS23410	COG1136	(ABC) transporter
CJO83_RS23430	COG3039	Transposase
CJO83_RS23465	COG0667	Aldo Keto reductase
CJO83_RS23535	COG2192	nodulation
CJO83_RS23550	COG2192	nodulation
CJO83_RS23575	COG4651	solute:proton antiporter activity
CJO83_RS23575	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CJO83_RS23600	COG3039	Transposase
CJO83_RS23625	COG3256	nitric oxide reductase
CJO83_RS23630	COG2188	Transcriptional regulator
CJO83_RS23635	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CJO83_RS23640	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CJO83_RS23675	COG0583	DNA-binding transcription factor activity
CJO83_RS23755	COG0705	Rhomboid family
CJO83_RS23780	COG3491	Belongs to the iron ascorbate-dependent oxidoreductase family
CJO83_RS23800	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CJO83_RS23815	COG3210	domain, Protein
CJO83_RS23860	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CJO83_RS23865	COG0642	Histidine kinase
CJO83_RS23885	COG0837	glucose binding
CJO83_RS23905	COG0589	response to stress
CJO83_RS23920	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CJO83_RS23925	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CJO83_RS23935	COG1845	cytochrome c oxidase, subunit III
CJO83_RS23960	COG2271	Major facilitator Superfamily
CJO83_RS23975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CJO83_RS23985	COG0765	amino acid transport
CJO83_RS23990	COG0010	Belongs to the arginase family
CJO83_RS23995	COG2197	response regulator
CJO83_RS24030	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CJO83_RS24035	COG1012	belongs to the aldehyde dehydrogenase family
CJO83_RS24045	COG0583	DNA-binding transcription factor activity
CJO83_RS24070	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CJO83_RS24075	COG2814	Major facilitator Superfamily
CJO83_RS24090	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CJO83_RS24155	COG1012	belongs to the aldehyde dehydrogenase family
CJO83_RS24160	COG0473	3-isopropylmalate dehydrogenase activity
CJO83_RS24170	COG2271	Major facilitator Superfamily
CJO83_RS24175	COG2721	sulfolactate sulfo-lyase activity
CJO83_RS24185	COG1475	DNA binding
CJO83_RS24195	COG3969	phosphoadenosine phosphosulfate
CJO83_RS24200	COG5295	Hep Hag repeat protein
CJO83_RS24200	COG5295	Hep Hag repeat protein
CJO83_RS24210	COG0784	Response regulator, receiver
CJO83_RS24210	COG2205	protein histidine kinase activity
CJO83_RS24215	COG3706	GGDEF domain
CJO83_RS24215	COG4251	negative regulation of phosphorylation
CJO83_RS24215	COG5001	Diguanylate cyclase
CJO83_RS24215	COG2203	Gaf domain
CJO83_RS24260	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
CJO83_RS24270	COG4213	ABC transporter substrate-binding protein
CJO83_RS24275	COG1129	ABC transporter
CJO83_RS24280	COG4214	carbohydrate transport
CJO83_RS24285	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CJO83_RS24290	COG1609	Transcriptional regulator
CJO83_RS24300	COG2207	Transcriptional regulator
CJO83_RS24380	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CJO83_RS24390	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CJO83_RS24400	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CJO83_RS24425	COG2204	response regulator
CJO83_RS24440	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CJO83_RS24460	COG2205	protein histidine kinase activity
CJO83_RS24470	COG2252	PERMEase