locus-tag	class	description
AM571_RS00010	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AM571_RS00015	COG0424	maF-like protein
AM571_RS00020	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AM571_RS00025	COG0237	dephospho-CoA kinase activity
AM571_RS00030	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM571_RS00035	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AM571_RS00040	COG3030	protein affecting phage T7 exclusion by the F plasmid
AM571_RS00050	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AM571_RS00075	COG0179	Fumarylacetoacetate (FAA) hydrolase
AM571_RS00095	COG0135	phosphoribosylanthranilate isomerase activity
AM571_RS00100	COG0133	tryptophan synthase activity
AM571_RS00105	COG0159	tryptophan synthase activity
AM571_RS00110	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AM571_RS00115	COG0285	dihydrofolate synthase activity
AM571_RS00130	COG2887	Belongs to the helicase family. UvrD subfamily
AM571_RS00135	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AM571_RS00140	COG3178	'Phosphotransferase
AM571_RS00145	COG2205	protein histidine kinase activity
AM571_RS00150	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AM571_RS00160	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AM571_RS00160	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM571_RS00170	COG0642	Histidine kinase
AM571_RS00175	COG0745	RESPONSE REGULATOR receiver
AM571_RS00180	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AM571_RS00195	COG1072	(Pantothenic acid kinase))
AM571_RS00200	COG0140	phosphoribosyl-ATP diphosphatase activity
AM571_RS00205	COG0107	imidazoleglycerol-phosphate synthase activity
AM571_RS00210	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AM571_RS00215	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AM571_RS00225	COG0131	Imidazoleglycerol-phosphate dehydratase
AM571_RS00230	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AM571_RS00240	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AM571_RS00270	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AM571_RS00280	COG1643	Atp-dependent helicase
AM571_RS00285	COG2423	ornithine cyclodeaminase activity
AM571_RS00320	COG4372	Transposase
AM571_RS00330	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AM571_RS00335	COG4372	Transposase
AM571_RS00340	COG3436	PFAM IS66 Orf2 family protein
AM571_RS00355	COG2963	transposase activity
AM571_RS00360	COG3436	PFAM IS66 Orf2 family protein
AM571_RS00375	COG0662	Cupin 2, conserved barrel domain protein
AM571_RS00385	COG0444	Belongs to the ABC transporter superfamily
AM571_RS00395	COG0601	transmembrane transport
AM571_RS00400	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AM571_RS00405	COG0747	negative chemotaxis
AM571_RS00410	COG0583	DNA-binding transcription factor activity
AM571_RS00420	COG3436	PFAM IS66 Orf2 family protein
AM571_RS00425	COG0583	DNA-binding transcription factor activity
AM571_RS00430	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AM571_RS00435	COG3485	protocatechuate 3,4-dioxygenase
AM571_RS00440	COG0667	Aldo Keto reductase
AM571_RS00450	COG1335	isochorismatase
AM571_RS00455	COG3845	ABC transporter
AM571_RS00460	COG1335	isochorismatase
AM571_RS00465	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM571_RS00470	COG1079	Belongs to the binding-protein-dependent transport system permease family
AM571_RS00490	COG1309	transcriptional regulator
AM571_RS00495	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM571_RS00510	COG2182	Extracellular solute-binding protein
AM571_RS00515	COG1609	Transcriptional regulator
AM571_RS00525	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AM571_RS00530	COG0673	inositol 2-dehydrogenase activity
AM571_RS00545	COG0673	inositol 2-dehydrogenase activity
AM571_RS00550	COG1309	transcriptional regulator
AM571_RS00560	COG1175	transmembrane transport
AM571_RS00565	COG0395	ABC-type sugar transport system, permease component
AM571_RS00575	COG3842	ATPase activity
AM571_RS00590	COG0246	Mannitol dehydrogenase
AM571_RS00595	COG1904	glucuronate isomerase
AM571_RS00600	COG2900	Belongs to the SlyX family
AM571_RS00605	COG1012	belongs to the aldehyde dehydrogenase family
AM571_RS00610	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AM571_RS00630	COG0539	negative regulation of cytoplasmic translation
AM571_RS00635	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AM571_RS00655	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AM571_RS00690	COG3474	cytochrome
AM571_RS00695	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AM571_RS00700	COG1605	Chorismate mutase
AM571_RS00700	COG0077	Prephenate dehydratase
AM571_RS00715	COG2378	regulation of single-species biofilm formation
AM571_RS00720	COG2816	NAD+ diphosphatase activity
AM571_RS00735	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AM571_RS00740	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AM571_RS00755	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AM571_RS00775	COG0779	Required for maturation of 30S ribosomal subunits
AM571_RS00790	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AM571_RS00795	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AM571_RS00800	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AM571_RS00810	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AM571_RS00815	COG1185	polyribonucleotide nucleotidyltransferase activity
AM571_RS00820	COG2813	Specifically methylates the guanine in position
AM571_RS00825	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AM571_RS00835	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AM571_RS00875	COG1396	sequence-specific DNA binding
AM571_RS00885	COG0484	heat shock protein binding
AM571_RS00890	COG0443	Heat shock 70 kDa protein
AM571_RS00895	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AM571_RS00910	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AM571_RS00925	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AM571_RS00925	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AM571_RS00935	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AM571_RS00940	COG3454	Phosphonate metabolism
AM571_RS00945	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AM571_RS00955	COG4778	phosphonate C-P lyase system protein PhnL
AM571_RS00960	COG4107	phosphonate C-P lyase system protein PhnK
AM571_RS00965	COG3627	carbon phosphorus lyase activity
AM571_RS00970	COG3626	phosphonate metabolism
AM571_RS00975	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
AM571_RS00980	COG3624	Phosphonate C-P lyase system protein PhnG
AM571_RS00985	COG2188	Transcriptional regulator
AM571_RS00990	COG0588	phosphoglycerate mutase activity
AM571_RS00995	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AM571_RS01000	COG1132	(ABC) transporter
AM571_RS01005	COG0837	glucose binding
AM571_RS01010	COG1803	Methylglyoxal synthase
AM571_RS01015	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
AM571_RS01025	COG4166	transmembrane transport
AM571_RS01030	COG4174	ABC transporter (Permease)
AM571_RS01035	COG4239	(ABC) transporter, permease
AM571_RS01040	COG4172	Belongs to the ABC transporter superfamily
AM571_RS01055	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AM571_RS01070	COG0174	glutamine synthetase
AM571_RS01095	COG1744	ABC transporter substrate-binding protein PnrA-like
AM571_RS01100	COG3845	ABC transporter
AM571_RS01105	COG4603	Belongs to the binding-protein-dependent transport system permease family
AM571_RS01110	COG1079	Belongs to the binding-protein-dependent transport system permease family
AM571_RS01125	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AM571_RS01130	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AM571_RS01140	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AM571_RS01145	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AM571_RS01150	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AM571_RS01185	COG4964	Belongs to the GSP D family
AM571_RS01215	COG1280	lysine exporter protein (LysE YggA)
AM571_RS01225	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AM571_RS01235	COG0791	NLP P60 protein
AM571_RS01240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM571_RS01255	COG0583	DNA-binding transcription factor activity
AM571_RS01270	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AM571_RS01285	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AM571_RS01310	COG3220	belongs to the UPF0276 family
AM571_RS01325	COG4944	Protein of unknown function (DUF1109)
AM571_RS01375	COG0481	GTPase activity
AM571_RS01380	COG1396	sequence-specific DNA binding
AM571_RS01395	COG2137	regulation of response to DNA damage stimulus
AM571_RS01425	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AM571_RS01445	COG0596	Alpha beta hydrolase
AM571_RS01470	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM571_RS01470	COG1017	nitric oxide dioxygenase activity
AM571_RS01475	COG0625	glutathione transferase activity
AM571_RS01490	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AM571_RS01495	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AM571_RS01500	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AM571_RS01505	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM571_RS01505	COG0072	phenylalanine-tRNA ligase activity
AM571_RS01515	COG3685	Protein conserved in bacteria
AM571_RS01525	COG0456	acetyltransferase
AM571_RS01565	COG1570	exodeoxyribonuclease VII activity
AM571_RS01570	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM571_RS01575	COG1846	Transcriptional regulator
AM571_RS01580	COG0697	spore germination
AM571_RS01585	COG2309	aminopeptidase activity
AM571_RS01605	COG1393	Belongs to the ArsC family
AM571_RS01615	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AM571_RS01635	COG0628	permease
AM571_RS01640	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AM571_RS01640	COG0519	Catalyzes the synthesis of GMP from XMP
AM571_RS01680	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AM571_RS01690	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AM571_RS01700	COG1968	undecaprenyl-diphosphatase activity
AM571_RS01715	COG0284	orotidine-5'-phosphate decarboxylase activity
AM571_RS01725	COG3963	phosphatidate phosphatase activity
AM571_RS01735	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AM571_RS01745	COG0189	ligase activity
AM571_RS01750	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AM571_RS01760	COG1335	isochorismatase
AM571_RS01770	COG1522	sequence-specific DNA binding
AM571_RS01780	COG0756	dUTP diphosphatase activity
AM571_RS01785	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AM571_RS01795	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AM571_RS01800	COG0640	Transcriptional regulator
AM571_RS01805	COG0583	DNA-binding transcription factor activity
AM571_RS01810	COG0625	glutathione transferase activity
AM571_RS01815	COG3119	arylsulfatase activity
AM571_RS01825	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AM571_RS01830	COG1877	trehalose-phosphatase activity
AM571_RS01845	COG2807	transmembrane transport
AM571_RS01850	COG2186	Transcriptional regulator
AM571_RS01860	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AM571_RS01880	COG2814	Major facilitator Superfamily
AM571_RS01890	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AM571_RS01910	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AM571_RS01915	COG2986	histidine ammonia-lyase
AM571_RS01920	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AM571_RS01925	COG2226	methyltransferase
AM571_RS01930	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AM571_RS01935	COG1024	Enoyl-CoA hydratase
AM571_RS01940	COG0268	Binds directly to 16S ribosomal RNA
AM571_RS01945	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AM571_RS01965	COG4774	siderophore transport
AM571_RS01980	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AM571_RS01985	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AM571_RS01995	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AM571_RS02000	COG1420	regulation of RNA biosynthetic process
AM571_RS02005	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AM571_RS02015	COG0071	Belongs to the small heat shock protein (HSP20) family
AM571_RS02025	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AM571_RS02030	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AM571_RS02035	COG1396	sequence-specific DNA binding
AM571_RS02040	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AM571_RS02050	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AM571_RS02055	COG1702	phosphate starvation-inducible protein PhoH
AM571_RS02060	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AM571_RS02075	COG0456	acetyltransferase
AM571_RS02085	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AM571_RS02095	COG0180	Tryptophanyl-tRNA synthetase
AM571_RS02125	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AM571_RS02130	COG0281	malic enzyme
AM571_RS02130	COG0280	phosphate acetyltransferase
AM571_RS02140	COG0784	Response regulator, receiver
AM571_RS02140	COG2205	protein histidine kinase activity
AM571_RS02140	COG5002	protein histidine kinase activity
AM571_RS02145	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AM571_RS02150	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM571_RS02155	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AM571_RS02155	COG0116	Belongs to the methyltransferase superfamily
AM571_RS02175	COG0776	regulation of translation
AM571_RS02180	COG0616	signal peptide processing
AM571_RS02180	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AM571_RS02190	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AM571_RS02195	COG1137	ATPase activity
AM571_RS02210	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AM571_RS02215	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM571_RS02220	COG0840	transmembrane signaling receptor activity
AM571_RS02225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM571_RS02235	COG0840	transmembrane signaling receptor activity
AM571_RS02240	COG0242	peptide deformylase activity
AM571_RS02250	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AM571_RS02255	COG0101	tRNA pseudouridine synthase activity
AM571_RS02265	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AM571_RS02270	COG2171	N-acyltransferase activity
AM571_RS02285	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AM571_RS02285	COG2169	Transcriptional regulator
AM571_RS02295	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AM571_RS02310	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AM571_RS02315	COG0706	membrane insertase activity
AM571_RS02320	COG0594	ribonuclease P activity
AM571_RS02325	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AM571_RS02330	COG0840	transmembrane signaling receptor activity
AM571_RS02360	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AM571_RS02365	COG1309	transcriptional regulator
AM571_RS02375	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM571_RS02380	COG1028	Short-chain dehydrogenase reductase Sdr
AM571_RS02385	COG3938	Belongs to the proline racemase family
AM571_RS02395	COG1940	carbohydrate kinase activity
AM571_RS02415	COG1072	(Pantothenic acid kinase))
AM571_RS02420	COG0418	dihydroorotase activity
AM571_RS02430	COG0702	epimerase
AM571_RS02440	COG3174	membrane
AM571_RS02445	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AM571_RS02480	COG0166	Belongs to the GPI family
AM571_RS02485	COG0318	PFAM AMP-dependent synthetase and ligase
AM571_RS02505	COG1174	glycine betaine transport
AM571_RS02510	COG1125	glycine betaine transport
AM571_RS02515	COG1174	glycine betaine transport
AM571_RS02520	COG1732	Glycine betaine
AM571_RS02530	COG0583	DNA-binding transcription factor activity
AM571_RS02535	COG3142	Participates in the control of copper homeostasis
AM571_RS02540	COG1063	alcohol dehydrogenase
AM571_RS02545	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM571_RS02570	COG2721	sulfolactate sulfo-lyase activity
AM571_RS02580	COG1028	Short-chain dehydrogenase reductase Sdr
AM571_RS02585	COG1376	ErfK ybiS ycfS ynhG family protein
AM571_RS02610	COG0300	oxidoreductase activity
AM571_RS02680	COG4964	Belongs to the GSP D family
AM571_RS02740	COG2326	polyphosphate kinase activity
AM571_RS02745	COG5002	protein histidine kinase activity
AM571_RS02755	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AM571_RS02760	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AM571_RS02765	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AM571_RS02770	COG2967	ApaG domain
AM571_RS02780	COG0717	Belongs to the dCTP deaminase family
AM571_RS02790	COG0840	transmembrane signaling receptor activity
AM571_RS02800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM571_RS02835	COG0167	dihydroorotate dehydrogenase activity
AM571_RS02845	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AM571_RS02855	COG4566	intracellular signal transduction
AM571_RS02860	COG4566	intracellular signal transduction
AM571_RS02895	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM571_RS02900	COG1959	2 iron, 2 sulfur cluster binding
AM571_RS02910	COG1201	RNA secondary structure unwinding
AM571_RS02935	COG0589	response to stress
AM571_RS02940	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AM571_RS02955	COG0730	response to heat
AM571_RS02975	COG1522	sequence-specific DNA binding
AM571_RS02990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM571_RS02995	COG0697	spore germination
AM571_RS03005	COG1960	acyl-CoA dehydrogenase activity
AM571_RS03010	COG0183	Belongs to the thiolase family
AM571_RS03015	COG1024	Enoyl-CoA hydratase
AM571_RS03015	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM571_RS03025	COG1278	Cold shock
AM571_RS03030	COG0784	Response regulator, receiver
AM571_RS03030	COG2198	Histidine kinase
AM571_RS03030	COG2205	protein histidine kinase activity
AM571_RS03035	COG1970	mechanosensitive ion channel activity
AM571_RS03040	COG0436	Aminotransferase
AM571_RS03050	COG1024	Enoyl-CoA hydratase
AM571_RS03095	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AM571_RS03105	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AM571_RS03110	COG5328	Belongs to the UPF0262 family
AM571_RS03115	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AM571_RS03120	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AM571_RS03125	COG0424	maF-like protein
AM571_RS03130	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AM571_RS03185	COG1595	DNA-templated transcription, initiation
AM571_RS03210	COG3474	cytochrome
AM571_RS03225	COG1733	regulation of RNA biosynthetic process
AM571_RS03245	COG0583	DNA-binding transcription factor activity
AM571_RS03270	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM571_RS03330	COG1215	transferase activity, transferring glycosyl groups
AM571_RS03335	COG0346	lactoylglutathione lyase activity
AM571_RS03340	COG2205	protein histidine kinase activity
AM571_RS03345	COG0784	Response regulator, receiver
AM571_RS03350	COG4251	negative regulation of phosphorylation
AM571_RS03360	COG2197	response regulator
AM571_RS03370	COG4251	negative regulation of phosphorylation
AM571_RS03385	COG4651	solute:proton antiporter activity
AM571_RS03385	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AM571_RS03395	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AM571_RS03400	COG0840	transmembrane signaling receptor activity
AM571_RS03410	COG0745	RESPONSE REGULATOR receiver
AM571_RS03415	COG2198	Histidine kinase
AM571_RS03415	COG0643	Histidine kinase
AM571_RS03420	COG0835	chemotaxis
AM571_RS03425	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AM571_RS03430	COG2201	protein-glutamate methylesterase activity
AM571_RS03435	COG0745	RESPONSE REGULATOR receiver
AM571_RS03440	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AM571_RS03450	COG1766	The M ring may be actively involved in energy transduction
AM571_RS03455	COG2771	luxR family
AM571_RS03470	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AM571_RS03475	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AM571_RS03480	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AM571_RS03485	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AM571_RS03490	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AM571_RS03495	COG4786	Flagellar basal body rod
AM571_RS03500	COG1157	protein secretion by the type III secretion system
AM571_RS03510	COG1815	bacterial-type flagellum-dependent cell motility
AM571_RS03515	COG1558	bacterial-type flagellum-dependent cell motility
AM571_RS03520	COG1677	Flagellar hook-basal body complex protein FliE
AM571_RS03525	COG4786	Flagellar basal body rod
AM571_RS03530	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
AM571_RS03535	COG1706	bacterial-type flagellum-dependent cell motility
AM571_RS03545	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AM571_RS03555	COG1338	Plays a role in the flagellum-specific transport system
AM571_RS03575	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AM571_RS03580	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AM571_RS03590	COG1360	Flagellar Motor Protein
AM571_RS03615	COG1749	Flagellar hook protein flgE
AM571_RS03635	COG5443	negative regulation of bacterial-type flagellum assembly
AM571_RS03645	COG4794	Type iii secretion
AM571_RS03650	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AM571_RS03655	COG1684	flagellar biosynthetic protein fliR
AM571_RS03695	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AM571_RS03705	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AM571_RS03710	COG1609	Transcriptional regulator
AM571_RS03715	COG1653	transport
AM571_RS03720	COG1175	transmembrane transport
AM571_RS03725	COG0395	ABC-type sugar transport system, permease component
AM571_RS03730	COG0366	Alpha amylase catalytic
AM571_RS03735	COG3842	ATPase activity
AM571_RS03745	COG0129	dihydroxy-acid dehydratase activity
AM571_RS03750	COG0363	glucosamine-6-phosphate deaminase activity
AM571_RS03755	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AM571_RS03760	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM571_RS03770	COG2081	HI0933 family
AM571_RS03775	COG0840	transmembrane signaling receptor activity
AM571_RS03775	COG2972	Histidine kinase
AM571_RS03780	COG2972	Histidine kinase
AM571_RS03780	COG0840	transmembrane signaling receptor activity
AM571_RS03805	COG2224	Isocitrate lyase
AM571_RS03815	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AM571_RS03820	COG3842	ATPase activity
AM571_RS03825	COG1176	ABC-type spermidine putrescine transport system, permease component I
AM571_RS03830	COG1177	transmembrane transport
AM571_RS03840	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AM571_RS03845	COG2205	protein histidine kinase activity
AM571_RS03890	COG1959	2 iron, 2 sulfur cluster binding
AM571_RS03895	COG0747	negative chemotaxis
AM571_RS03900	COG0601	transmembrane transport
AM571_RS03905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM571_RS03910	COG0444	Belongs to the ABC transporter superfamily
AM571_RS03915	COG4608	Belongs to the ABC transporter superfamily
AM571_RS03920	COG3265	gluconokinase activity
AM571_RS03925	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM571_RS03930	COG1755	Isoprenylcysteine carboxyl methyltransferase
AM571_RS03945	COG1595	DNA-templated transcription, initiation
AM571_RS03965	COG0488	(ABC) transporter
AM571_RS03970	COG2195	Cleaves the N-terminal amino acid of tripeptides
AM571_RS03975	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AM571_RS04015	COG5002	protein histidine kinase activity
AM571_RS04015	COG0784	Response regulator, receiver
AM571_RS04050	COG0640	Transcriptional regulator
AM571_RS04055	COG2186	Transcriptional regulator
AM571_RS04065	COG0747	negative chemotaxis
AM571_RS04070	COG0601	transmembrane transport
AM571_RS04075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM571_RS04080	COG4172	Belongs to the ABC transporter superfamily
AM571_RS04090	COG1609	Transcriptional regulator
AM571_RS04095	COG1653	transport
AM571_RS04105	COG1175	transmembrane transport
AM571_RS04110	COG3842	ATPase activity
AM571_RS04145	COG3047	cAMP biosynthetic process
AM571_RS04145	COG2885	chlorophyll binding
AM571_RS04185	COG3971	2-oxopent-4-enoate hydratase activity
AM571_RS04190	COG3485	protocatechuate 3,4-dioxygenase
AM571_RS04205	COG0765	amino acid transport
AM571_RS04210	COG0765	amino acid transport
AM571_RS04215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM571_RS04220	COG1126	abc transporter atp-binding protein
AM571_RS04225	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AM571_RS04235	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AM571_RS04240	COG0673	inositol 2-dehydrogenase activity
AM571_RS04245	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AM571_RS04270	COG0248	Ppx GppA phosphatase
AM571_RS04275	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AM571_RS04285	COG0477	Major facilitator Superfamily
AM571_RS04305	COG0412	Dienelactone hydrolase
AM571_RS04315	COG0583	DNA-binding transcription factor activity
AM571_RS04340	COG0306	phosphate transporter
AM571_RS04350	COG0583	DNA-binding transcription factor activity
AM571_RS04355	COG0277	FAD linked oxidase domain protein
AM571_RS04360	COG0277	FAD linked oxidase domain protein
AM571_RS04370	COG0247	lactate metabolic process
AM571_RS04380	COG1388	LysM domain
AM571_RS04380	COG1376	ErfK ybiS ycfS ynhG family protein
AM571_RS04385	COG1376	ErfK ybiS ycfS ynhG family protein
AM571_RS04390	COG2818	Glycosylase
AM571_RS04405	COG0667	Aldo Keto reductase
AM571_RS04415	COG0124	histidyl-tRNA synthetase
AM571_RS04420	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AM571_RS04425	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AM571_RS04430	COG2259	Doxx family
AM571_RS04435	COG0625	glutathione transferase activity
AM571_RS04445	COG0459	protein refolding
AM571_RS04450	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AM571_RS04460	COG0196	riboflavin kinase activity
AM571_RS04475	COG0590	tRNA wobble adenosine to inosine editing
AM571_RS04480	COG1187	pseudouridine synthase activity
AM571_RS04485	COG0742	ribosomal rna small subunit methyltransferase
AM571_RS04495	COG0475	glutathione-regulated potassium exporter activity
AM571_RS04495	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AM571_RS04500	COG0312	modulator of DNA gyrase
AM571_RS04505	COG0483	inositol monophosphate 1-phosphatase activity
AM571_RS04515	COG1519	Transferase
AM571_RS04520	COG0546	phosphoglycolate phosphatase activity
AM571_RS04525	COG1663	tetraacyldisaccharide 4'-kinase activity
AM571_RS04535	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AM571_RS04540	COG0745	RESPONSE REGULATOR receiver
AM571_RS04545	COG5001	Diguanylate cyclase
AM571_RS04555	COG3386	PFAM SMP-30 Gluconolaconase
AM571_RS04560	COG0800	Aldolase
AM571_RS04565	COG3734	2-keto-3-deoxy-galactonokinase
AM571_RS04570	COG1028	Short-chain dehydrogenase reductase Sdr
AM571_RS04575	COG1414	Transcriptional regulator
AM571_RS04580	COG2197	response regulator
AM571_RS04590	COG0489	protein tyrosine kinase activity
AM571_RS04600	COG0598	Magnesium transport protein CorA
AM571_RS04605	COG3158	transport of potassium into the cell
AM571_RS04620	COG0356	it plays a direct role in the translocation of protons across the membrane
AM571_RS04625	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AM571_RS04630	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AM571_RS04635	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AM571_RS04655	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AM571_RS04675	COG0521	Mo-molybdopterin cofactor biosynthetic process
AM571_RS04680	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AM571_RS04690	COG0142	geranyltranstransferase activity
AM571_RS04705	COG1914	H( )-stimulated, divalent metal cation uptake system
AM571_RS04720	COG0752	glycyl-tRNA synthetase alpha subunit
AM571_RS04725	COG1704	LemA family
AM571_RS04730	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AM571_RS04740	COG0151	Belongs to the GarS family
AM571_RS04750	COG1683	Conserved Protein
AM571_RS04755	COG0751	glycine-tRNA ligase activity
AM571_RS04760	COG2183	response to ionizing radiation
AM571_RS04765	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AM571_RS04780	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AM571_RS04800	COG0009	L-threonylcarbamoyladenylate synthase
AM571_RS04810	COG4638	Rieske (2fe-2S)
AM571_RS04825	COG1960	acyl-CoA dehydrogenase activity
AM571_RS04845	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AM571_RS04855	COG0840	transmembrane signaling receptor activity
AM571_RS04860	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AM571_RS04865	COG1741	Belongs to the pirin family
AM571_RS04875	COG1722	exodeoxyribonuclease VII activity
AM571_RS04880	COG0123	including yeast histone deacetylase and acetoin utilization protein
AM571_RS04890	COG1268	BioY protein
AM571_RS04895	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AM571_RS04900	COG1122	ATPase activity
AM571_RS04905	COG3214	Protein conserved in bacteria
AM571_RS04910	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AM571_RS04910	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AM571_RS04915	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AM571_RS04935	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AM571_RS04940	COG0484	heat shock protein binding
AM571_RS04950	COG0259	pyridoxamine-phosphate oxidase activity
AM571_RS04960	COG1686	Belongs to the peptidase S11 family
AM571_RS04975	COG0312	modulator of DNA gyrase
AM571_RS04985	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AM571_RS04985	COG1565	acr, cog1565
AM571_RS04990	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AM571_RS04995	COG0109	protoheme IX farnesyltransferase activity
AM571_RS05000	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AM571_RS05020	COG3346	SURF1 family
AM571_RS05025	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AM571_RS05030	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AM571_RS05035	COG0328	RNA-DNA hybrid ribonuclease activity
AM571_RS05045	COG2186	Transcriptional regulator
AM571_RS05050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM571_RS05055	COG0765	amino acid transport
AM571_RS05060	COG0765	amino acid transport
AM571_RS05075	COG2186	Transcriptional regulator
AM571_RS05090	COG0803	Belongs to the bacterial solute-binding protein 9 family
AM571_RS05095	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM571_RS05100	COG1121	(ABC) transporter
AM571_RS05115	COG0678	peroxiredoxin activity
AM571_RS05115	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AM571_RS05125	COG1678	Uncharacterized ACR, COG1678
AM571_RS05140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM571_RS05145	COG0612	Peptidase, M16
AM571_RS05160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM571_RS05180	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AM571_RS05205	COG1196	nuclear chromosome segregation
AM571_RS05210	COG0574	Belongs to the PEP-utilizing enzyme family
AM571_RS05210	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM571_RS05240	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM571_RS05285	COG0175	sulfate reduction
AM571_RS05290	COG0175	sulfate reduction
AM571_RS05295	COG1959	2 iron, 2 sulfur cluster binding
AM571_RS05310	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AM571_RS05315	COG1012	belongs to the aldehyde dehydrogenase family
AM571_RS05320	COG1309	transcriptional regulator
AM571_RS05340	COG3321	synthase
AM571_RS05340	COG1028	Short-chain dehydrogenase reductase Sdr
AM571_RS05340	COG0604	alcohol dehydrogenase
AM571_RS05380	COG0625	glutathione transferase activity
AM571_RS05390	COG0583	DNA-binding transcription factor activity
AM571_RS05400	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AM571_RS05405	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AM571_RS05415	COG0625	glutathione transferase activity
AM571_RS05435	COG1793	dna ligase
AM571_RS05450	COG1376	ErfK ybiS ycfS ynhG family protein
AM571_RS05455	COG1376	ErfK ybiS ycfS ynhG family protein
AM571_RS05460	COG3409	Peptidoglycan-binding domain 1 protein
AM571_RS05460	COG3773	Cell wall hydrolase
AM571_RS05475	COG1846	Transcriptional regulator
AM571_RS05480	COG1764	response to oxidative stress
AM571_RS05485	COG1846	Transcriptional regulator
AM571_RS05525	COG0488	(ABC) transporter
AM571_RS05530	COG2824	Alkylphosphonate utilization operon protein PhnA
AM571_RS05535	COG0433	COG0433 Predicted ATPase
AM571_RS05545	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AM571_RS05550	COG4106	trans-aconitate 2-methyltransferase activity
AM571_RS05565	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AM571_RS05580	COG0753	catalase activity
AM571_RS05585	COG2814	Major facilitator Superfamily
AM571_RS05590	COG0730	response to heat
AM571_RS05625	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AM571_RS05655	COG2010	Cytochrome c
AM571_RS05690	COG4993	Dehydrogenase
AM571_RS05695	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AM571_RS05745	COG2514	catechol 2,3-dioxygenase activity
AM571_RS05755	COG1272	protein, Hemolysin III
AM571_RS05765	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AM571_RS05775	COG2111	Na H antiporter
AM571_RS05775	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AM571_RS05780	COG2111	Na H antiporter
AM571_RS05785	COG1006	Multisubunit Na H antiporter MnhC subunit
AM571_RS05795	COG0651	ATP synthesis coupled electron transport
AM571_RS05800	COG1863	multisubunit Na H antiporter MnhE subunit
AM571_RS05805	COG2212	antiporter activity
AM571_RS05810	COG1320	monovalent cation:proton antiporter activity
AM571_RS05815	COG4957	zinc ion binding
AM571_RS05830	COG1959	2 iron, 2 sulfur cluster binding
AM571_RS05850	COG2166	iron-sulfur cluster assembly
AM571_RS05865	COG2205	protein histidine kinase activity
AM571_RS05950	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AM571_RS05955	COG2983	Belongs to the UPF0260 family
AM571_RS05995	COG4235	cytochrome complex assembly
AM571_RS06000	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AM571_RS06005	COG1138	Cytochrome C-type biogenesis protein
AM571_RS06010	COG3088	subunit of a heme lyase
AM571_RS06030	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM571_RS06035	COG0745	RESPONSE REGULATOR receiver
AM571_RS06040	COG2205	protein histidine kinase activity
AM571_RS06045	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AM571_RS06050	COG2205	protein histidine kinase activity
AM571_RS06050	COG2202	Pas domain
AM571_RS06055	COG0308	aminopeptidase N
AM571_RS06060	COG3290	protein histidine kinase activity
AM571_RS06060	COG0840	transmembrane signaling receptor activity
AM571_RS06080	COG1573	uracil-dna glycosylase
AM571_RS06085	COG0443	Heat shock 70 kDa protein
AM571_RS06120	COG2239	Acts as a magnesium transporter
AM571_RS06130	COG1733	regulation of RNA biosynthetic process
AM571_RS06135	COG2814	Major facilitator Superfamily
AM571_RS06155	COG0174	glutamine synthetase
AM571_RS06165	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AM571_RS06170	COG0463	Glycosyl transferase, family 2
AM571_RS06180	COG4941	Belongs to the sigma-70 factor family
AM571_RS06190	COG3795	YCII-related domain
AM571_RS06205	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AM571_RS06210	COG0625	glutathione transferase activity
AM571_RS06225	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AM571_RS06260	COG3718	enzyme involved in inositol metabolism
AM571_RS06265	COG1082	Xylose isomerase domain protein TIM barrel
AM571_RS06270	COG3962	Belongs to the TPP enzyme family
AM571_RS06275	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM571_RS06285	COG0673	inositol 2-dehydrogenase activity
AM571_RS06320	COG0596	Alpha beta hydrolase
AM571_RS06320	COG2945	thiolester hydrolase activity
AM571_RS06325	COG0741	lytic transglycosylase activity
AM571_RS06330	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM571_RS06335	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AM571_RS06350	COG1758	RNA polymerase activity
AM571_RS06370	COG0736	holo-[acyl-carrier-protein] synthase activity
AM571_RS06375	COG0681	Belongs to the peptidase S26 family
AM571_RS06380	COG0571	ribonuclease III activity
AM571_RS06385	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AM571_RS06395	COG1381	Involved in DNA repair and RecF pathway recombination
AM571_RS06410	COG1418	mRNA catabolic process
AM571_RS06415	COG5001	Diguanylate cyclase
AM571_RS06415	COG3300	MHYT domain
AM571_RS06425	COG2032	superoxide dismutase activity
AM571_RS06435	COG0668	transmembrane transport
AM571_RS06445	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AM571_RS06470	COG1051	belongs to the nudix hydrolase family
AM571_RS06475	COG1742	UPF0060 membrane protein
AM571_RS06485	COG1183	phosphatidylcholine synthase activity
AM571_RS06490	COG0688	phosphatidylethanolamine metabolic process
AM571_RS06495	COG5265	(ABC) transporter
AM571_RS06500	COG1388	LysM domain
AM571_RS06515	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AM571_RS06540	COG0215	cysteine-tRNA ligase activity
AM571_RS06550	COG4221	oxidoreductase activity
AM571_RS06555	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AM571_RS06560	COG1286	toxin biosynthetic process
AM571_RS06570	COG1280	lysine exporter protein (LysE YggA)
AM571_RS06575	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AM571_RS06580	COG0305	Participates in initiation and elongation during chromosome replication
AM571_RS06595	COG0359	binds to the 23S rRNA
AM571_RS06605	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AM571_RS06610	COG0360	Binds together with S18 to 16S ribosomal RNA
AM571_RS06615	COG0667	Aldo Keto reductase
AM571_RS06620	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AM571_RS06630	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AM571_RS06635	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM571_RS06640	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AM571_RS06645	COG1561	YicC-like family, N-terminal region
AM571_RS06650	COG0194	GDP metabolic process
AM571_RS06655	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AM571_RS06660	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AM571_RS06670	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AM571_RS06685	COG0671	phosphoesterase, PA-phosphatase related
AM571_RS06690	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AM571_RS06700	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AM571_RS06710	COG0488	(ABC) transporter
AM571_RS06715	COG0105	UTP biosynthetic process
AM571_RS06735	COG0314	molybdopterin synthase activity
AM571_RS06755	COG0322	excinuclease ABC activity
AM571_RS06760	COG1028	Short-chain dehydrogenase reductase Sdr
AM571_RS06775	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AM571_RS06780	COG0243	molybdopterin cofactor binding
AM571_RS06795	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AM571_RS06800	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AM571_RS06805	COG0628	permease
AM571_RS06830	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AM571_RS06835	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AM571_RS06840	COG2132	Multicopper oxidase
AM571_RS06845	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AM571_RS06855	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AM571_RS06870	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AM571_RS06880	COG0113	porphobilinogen synthase activity
AM571_RS06900	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AM571_RS06905	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AM571_RS06910	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AM571_RS06910	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AM571_RS06935	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AM571_RS06940	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AM571_RS06945	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AM571_RS06965	COG0416	fatty acid biosynthetic process
AM571_RS06970	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AM571_RS06975	COG0776	regulation of translation
AM571_RS06990	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM571_RS06995	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AM571_RS07030	COG0629	single-stranded DNA binding
AM571_RS07350	COG0297	glycogen (starch) synthase activity
AM571_RS07375	COG1612	heme a metabolic process
AM571_RS07385	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AM571_RS07390	COG0010	Belongs to the arginase family
AM571_RS07400	COG1522	sequence-specific DNA binding
AM571_RS07405	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AM571_RS07410	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AM571_RS07440	COG1832	CoA-binding protein
AM571_RS07460	COG2124	cytochrome p450
AM571_RS07465	COG3706	GGDEF domain
AM571_RS07470	COG0740	serine-type endopeptidase activity
AM571_RS07475	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AM571_RS07480	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AM571_RS07485	COG0776	regulation of translation
AM571_RS07495	COG0667	Aldo Keto reductase
AM571_RS07515	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM571_RS07520	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM571_RS07525	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM571_RS07530	COG0649	NAD binding
AM571_RS07540	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AM571_RS07545	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AM571_RS07550	COG3743	rRNA binding
AM571_RS07550	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AM571_RS07560	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AM571_RS07565	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM571_RS07575	COG0713	ATP synthesis coupled electron transport
AM571_RS07590	COG1007	ATP synthesis coupled electron transport
AM571_RS07595	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AM571_RS07595	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AM571_RS07605	COG0346	lactoylglutathione lyase activity
AM571_RS07615	COG0442	prolyl-tRNA aminoacylation
AM571_RS07625	COG1136	(ABC) transporter
AM571_RS07655	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AM571_RS07675	COG0784	Response regulator, receiver
AM571_RS07685	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AM571_RS07690	COG0477	Major facilitator Superfamily
AM571_RS07700	COG0557	exoribonuclease II activity
AM571_RS07705	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AM571_RS07710	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AM571_RS07720	COG0540	Belongs to the ATCase OTCase family
AM571_RS07725	COG1960	acyl-CoA dehydrogenase activity
AM571_RS07745	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AM571_RS07750	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AM571_RS07755	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AM571_RS07760	COG0154	amidase activity
AM571_RS07770	COG3811	Belongs to the UPF0386 family
AM571_RS07780	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AM571_RS07800	COG4765	Protein conserved in bacteria
AM571_RS07805	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AM571_RS07815	COG0511	ligase activity, forming carbon-carbon bonds
AM571_RS07820	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AM571_RS07830	COG0436	Aminotransferase
AM571_RS07845	COG1530	ribonuclease E activity
AM571_RS07850	COG0860	N-Acetylmuramoyl-L-alanine amidase
AM571_RS07855	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AM571_RS07870	COG1132	(ABC) transporter
AM571_RS07875	COG0477	Major facilitator Superfamily
AM571_RS07890	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AM571_RS07920	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM571_RS07940	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AM571_RS07955	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AM571_RS07960	COG0250	Participates in transcription elongation, termination and antitermination
AM571_RS07965	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AM571_RS07970	COG0081	regulation of translation
AM571_RS07975	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AM571_RS07980	COG0222	ribosome binding
AM571_RS07985	COG0085	RNA polymerase activity
AM571_RS07990	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AM571_RS08005	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AM571_RS08010	COG0049	tRNA binding
AM571_RS08015	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AM571_RS08020	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AM571_RS08025	COG0051	transcription antitermination factor activity, RNA binding
AM571_RS08030	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AM571_RS08035	COG0088	Forms part of the polypeptide exit tunnel
AM571_RS08040	COG0089	rRNA binding
AM571_RS08045	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AM571_RS08050	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AM571_RS08055	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AM571_RS08060	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AM571_RS08065	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AM571_RS08070	COG0255	Belongs to the universal ribosomal protein uL29 family
AM571_RS08075	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AM571_RS08080	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AM571_RS08085	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AM571_RS08090	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AM571_RS08095	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AM571_RS08100	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AM571_RS08105	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AM571_RS08110	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AM571_RS08115	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AM571_RS08120	COG1841	ribosomal large subunit assembly
AM571_RS08125	COG0200	Binds to the 23S rRNA
AM571_RS08135	COG0563	adenylate kinase activity
AM571_RS08140	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AM571_RS08145	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AM571_RS08150	COG0202	RNA polymerase activity
AM571_RS08155	COG0203	ribosomal protein L17
AM571_RS08165	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AM571_RS08170	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AM571_RS08175	COG0129	dihydroxy-acid dehydratase activity
AM571_RS08190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM571_RS08195	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AM571_RS08205	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AM571_RS08215	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AM571_RS08220	COG1028	Short-chain dehydrogenase reductase Sdr
AM571_RS08225	COG0583	DNA-binding transcription factor activity
AM571_RS08235	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AM571_RS08285	COG2132	Multicopper oxidase
AM571_RS08315	COG3038	cytochrome b561
AM571_RS08340	COG0789	Transcriptional regulator
AM571_RS08375	COG1129	ABC transporter
AM571_RS08380	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM571_RS08385	COG1737	Transcriptional regulator
AM571_RS08390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM571_RS08395	COG1609	Transcriptional regulator
AM571_RS08400	COG0673	inositol 2-dehydrogenase activity
AM571_RS08410	COG1024	Enoyl-CoA hydratase
AM571_RS08415	COG1012	belongs to the aldehyde dehydrogenase family
AM571_RS08420	COG1653	transport
AM571_RS08425	COG1175	transmembrane transport
AM571_RS08430	COG0395	ABC-type sugar transport system, permease component
AM571_RS08435	COG3842	ATPase activity
AM571_RS08450	COG0673	inositol 2-dehydrogenase activity
AM571_RS08455	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AM571_RS08460	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AM571_RS08460	COG1672	PFAM Archaeal ATPase
AM571_RS08490	COG1917	Cupin 2, conserved barrel domain protein
AM571_RS08490	COG4977	sequence-specific DNA binding
AM571_RS08530	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AM571_RS08545	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AM571_RS08555	COG1546	Belongs to the CinA family
AM571_RS08555	COG1058	Belongs to the CinA family
AM571_RS08580	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AM571_RS08620	COG1733	regulation of RNA biosynthetic process
AM571_RS08625	COG2085	NADP oxidoreductase coenzyme F420-dependent
AM571_RS08630	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AM571_RS08635	COG0583	DNA-binding transcription factor activity
AM571_RS08640	COG0737	Belongs to the 5'-nucleotidase family
AM571_RS08655	COG1522	sequence-specific DNA binding
AM571_RS08660	COG0686	Belongs to the AlaDH PNT family
AM571_RS08675	COG2897	thiosulfate sulfurtransferase activity
AM571_RS08690	COG1028	Short-chain dehydrogenase reductase Sdr
AM571_RS08850	COG0582	viral genome integration into host DNA
AM571_RS08865	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AM571_RS08875	COG0525	valine-tRNA ligase activity
AM571_RS08905	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AM571_RS08910	COG0018	arginyl-trna synthetase
AM571_RS08925	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AM571_RS08930	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AM571_RS08935	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AM571_RS08940	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AM571_RS08945	COG0805	protein transport
AM571_RS08950	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AM571_RS08955	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AM571_RS08960	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AM571_RS08965	COG0739	heme binding
AM571_RS08975	COG1862	Preprotein translocase
AM571_RS09000	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AM571_RS09035	COG2197	response regulator
AM571_RS09050	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AM571_RS09055	COG1215	transferase activity, transferring glycosyl groups
AM571_RS09100	COG0544	peptidyl-prolyl cis-trans isomerase activity
AM571_RS09115	COG3920	Histidine kinase
AM571_RS09120	COG0024	Methionine aminopeptidase
AM571_RS09140	COG3243	poly(R)-hydroxyalkanoic acid synthase
AM571_RS09150	COG0436	Aminotransferase
AM571_RS09160	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AM571_RS09165	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AM571_RS09170	COG1091	dTDP-4-dehydrorhamnose reductase activity
AM571_RS09175	COG1088	dTDP-glucose 4,6-dehydratase activity
AM571_RS09180	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
AM571_RS09195	COG0673	inositol 2-dehydrogenase activity
AM571_RS09200	COG1181	Belongs to the D-alanine--D-alanine ligase family
AM571_RS09220	COG1216	Glycosyl transferase, family 2
AM571_RS09220	COG0463	Glycosyl transferase, family 2
AM571_RS09260	COG1278	Cold shock
AM571_RS09335	COG1126	abc transporter atp-binding protein
AM571_RS09340	COG0765	amino acid transport
AM571_RS09345	COG4597	amino acid ABC transporter
AM571_RS09350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM571_RS09355	COG0626	cystathionine gamma-synthase activity
AM571_RS09370	COG2267	carboxylic ester hydrolase activity
AM571_RS09395	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AM571_RS09405	COG0537	adenosine 5'-monophosphoramidase activity
AM571_RS09415	COG0512	Glutamine amidotransferase of anthranilate synthase
AM571_RS09435	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AM571_RS09440	COG0052	Belongs to the universal ribosomal protein uS2 family
AM571_RS09445	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AM571_RS09450	COG0528	UMP kinase activity
AM571_RS09455	COG0233	cytoplasmic translational termination
AM571_RS09460	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AM571_RS09470	COG0750	zinc metalloprotease
AM571_RS09475	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM571_RS09480	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AM571_RS09485	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AM571_RS09490	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AM571_RS09495	COG3494	Protein of unknown function (DUF1009)
AM571_RS09500	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AM571_RS09505	COG0372	Belongs to the citrate synthase family
AM571_RS09515	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AM571_RS09525	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AM571_RS09535	COG0148	phosphopyruvate hydratase activity
AM571_RS09545	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AM571_RS09550	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM571_RS09550	COG0022	dehydrogenase e1 component
AM571_RS09555	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM571_RS09570	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM571_RS09585	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AM571_RS09595	COG2867	negative regulation of translational initiation
AM571_RS09605	COG1546	Belongs to the CinA family
AM571_RS09605	COG1058	Belongs to the CinA family
AM571_RS09610	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AM571_RS09610	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AM571_RS09620	COG3852	Histidine kinase
AM571_RS09625	COG2204	response regulator
AM571_RS09630	COG5000	phosphorelay sensor kinase activity
AM571_RS09635	COG2204	response regulator
AM571_RS09645	COG1923	regulation of RNA biosynthetic process
AM571_RS09650	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AM571_RS09655	COG3956	TIGRFAM MazG family protein
AM571_RS09675	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM571_RS09685	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM571_RS09690	COG0785	Cytochrome C biogenesis protein
AM571_RS09705	COG1484	DNA-dependent DNA replication
AM571_RS09710	COG4584	PFAM Integrase catalytic
AM571_RS09765	COG1566	PFAM secretion protein HlyD family protein
AM571_RS09770	COG1136	(ABC) transporter
AM571_RS09770	COG0577	efflux transmembrane transporter activity
AM571_RS09775	COG1136	(ABC) transporter
AM571_RS09775	COG0577	efflux transmembrane transporter activity
AM571_RS09780	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM571_RS09795	COG1183	phosphatidylcholine synthase activity
AM571_RS09805	COG3845	ABC transporter
AM571_RS09810	COG4603	Belongs to the binding-protein-dependent transport system permease family
AM571_RS09815	COG1079	Belongs to the binding-protein-dependent transport system permease family
AM571_RS09825	COG1879	ABC-type sugar transport system periplasmic component
AM571_RS09830	COG1129	ABC transporter
AM571_RS09835	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM571_RS09840	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM571_RS09845	COG2186	Transcriptional regulator
AM571_RS09850	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AM571_RS09855	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AM571_RS09865	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AM571_RS09875	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AM571_RS09885	COG4166	transmembrane transport
AM571_RS09900	COG0174	glutamine synthetase
AM571_RS09905	COG0347	Belongs to the P(II) protein family
AM571_RS09910	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AM571_RS09910	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AM571_RS09920	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AM571_RS09925	COG0629	single-stranded DNA binding
AM571_RS09945	COG2095	MarC family integral membrane protein
AM571_RS09950	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AM571_RS09960	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AM571_RS09975	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AM571_RS09980	COG0343	queuine tRNA-ribosyltransferase activity
AM571_RS09990	COG2814	Major facilitator Superfamily
AM571_RS10015	COG0640	Transcriptional regulator
AM571_RS10025	COG2801	Transposase and inactivated derivatives
AM571_RS10030	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AM571_RS10070	COG2010	Cytochrome c
AM571_RS10085	COG3278	Belongs to the heme-copper respiratory oxidase family
AM571_RS10095	COG3547	Transposase (IS116 IS110 IS902 family)
AM571_RS10100	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AM571_RS10105	COG2801	Transposase and inactivated derivatives
AM571_RS10110	COG2801	Transposase and inactivated derivatives
AM571_RS10115	COG3547	Transposase (IS116 IS110 IS902 family)
AM571_RS10120	COG2226	methyltransferase
AM571_RS10125	COG0321	lipoyl(octanoyl) transferase activity
AM571_RS10125	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AM571_RS10130	COG0084	hydrolase, TatD family'
AM571_RS10135	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM571_RS10140	COG0730	response to heat
AM571_RS10150	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AM571_RS10215	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AM571_RS10220	COG0134	indole-3-glycerol-phosphate synthase activity
AM571_RS10225	COG0315	cyclic pyranopterin monophosphate synthase activity
AM571_RS10245	COG0513	Belongs to the DEAD box helicase family
AM571_RS10260	COG0372	Belongs to the citrate synthase family
AM571_RS10265	COG0372	Belongs to the citrate synthase family
AM571_RS10270	COG0504	CTP synthase activity
AM571_RS10280	COG0149	triose-phosphate isomerase activity
AM571_RS10290	COG0187	DNA topoisomerase II activity
AM571_RS10305	COG0628	permease
AM571_RS10340	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AM571_RS10350	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AM571_RS10360	COG0302	gtp cyclohydrolase
AM571_RS10365	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AM571_RS10370	COG1752	Esterase of the alpha-beta hydrolase superfamily
AM571_RS10375	COG2239	Acts as a magnesium transporter
AM571_RS10415	COG1686	Belongs to the peptidase S11 family
AM571_RS10430	COG1760	l-serine dehydratase
AM571_RS10455	COG2239	Acts as a magnesium transporter
AM571_RS10460	COG0242	peptide deformylase activity
AM571_RS10475	COG0321	lipoyl(octanoyl) transferase activity
AM571_RS10490	COG4770	biotin carboxylase activity
AM571_RS10500	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AM571_RS10505	COG1671	Belongs to the UPF0178 family
AM571_RS10510	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AM571_RS10520	COG2259	Doxx family
AM571_RS10525	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AM571_RS10540	COG0546	phosphoglycolate phosphatase activity
AM571_RS10545	COG0564	pseudouridine synthase activity
AM571_RS10550	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AM571_RS10570	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AM571_RS10575	COG0509	glycine decarboxylation via glycine cleavage system
AM571_RS10580	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AM571_RS10580	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AM571_RS10600	COG1309	transcriptional regulator
AM571_RS10610	COG0316	Belongs to the HesB IscA family
AM571_RS10615	COG2151	metal-sulfur cluster biosynthetic enzyme
AM571_RS10620	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AM571_RS10625	COG0719	Fe-S assembly protein
AM571_RS10630	COG0396	ATPase activity
AM571_RS10635	COG0719	Fe-S assembly protein
AM571_RS10645	COG2945	thiolester hydrolase activity
AM571_RS10655	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AM571_RS10660	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AM571_RS10670	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AM571_RS10675	COG2833	Protein of unknown function (DUF455)
AM571_RS10680	COG1196	nuclear chromosome segregation
AM571_RS10680	COG0741	lytic transglycosylase activity
AM571_RS10680	COG0739	heme binding
AM571_RS10685	COG0513	Belongs to the DEAD box helicase family
AM571_RS10705	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AM571_RS10705	COG3608	succinylglutamate desuccinylase aspartoacylase
AM571_RS10720	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AM571_RS10725	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM571_RS10745	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AM571_RS10765	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AM571_RS10770	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AM571_RS10780	COG0047	phosphoribosylformylglycinamidine synthase activity
AM571_RS10795	COG2186	Transcriptional regulator
AM571_RS10800	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AM571_RS10820	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AM571_RS10825	COG2814	Major facilitator Superfamily
AM571_RS10830	COG2814	Major facilitator Superfamily
AM571_RS10840	COG0483	inositol monophosphate 1-phosphatase activity
AM571_RS10845	COG0037	tRNA processing
AM571_RS10850	COG2066	Belongs to the glutaminase family
AM571_RS10855	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AM571_RS10870	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AM571_RS10875	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AM571_RS10885	COG0538	isocitrate dehydrogenase activity
AM571_RS10905	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AM571_RS10910	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AM571_RS10915	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM571_RS10920	COG2313	pseudouridylate synthase activity
AM571_RS10935	COG3344	reverse transcriptase
AM571_RS10950	COG3106	COG3106 Predicted ATPase
AM571_RS10955	COG3768	UPF0283 membrane protein
AM571_RS10965	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AM571_RS10985	COG0633	Ferredoxin
AM571_RS11010	COG1127	ABC transporter
AM571_RS11015	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AM571_RS11020	COG4948	Mandelate Racemase Muconate Lactonizing
AM571_RS11025	COG2814	Major facilitator Superfamily
AM571_RS11035	COG0281	malic enzyme
AM571_RS11035	COG0280	phosphate acetyltransferase
AM571_RS11045	COG0778	Nitroreductase
AM571_RS11050	COG0823	Involved in the tonB-independent uptake of proteins
AM571_RS11060	COG1368	sulfuric ester hydrolase activity
AM571_RS11075	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AM571_RS11095	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AM571_RS11100	COG0546	phosphoglycolate phosphatase activity
AM571_RS11105	COG2989	Protein conserved in bacteria
AM571_RS11110	COG0114	fumarate hydratase activity
AM571_RS11115	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AM571_RS11115	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AM571_RS11125	COG3706	GGDEF domain
AM571_RS11140	COG1846	Transcriptional regulator
AM571_RS11155	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AM571_RS11165	COG3237	CsbD-like
AM571_RS11185	COG0746	molybdenum cofactor guanylyltransferase activity
AM571_RS11190	COG1763	Mo-molybdopterin cofactor biosynthetic process
AM571_RS11200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM571_RS11215	COG5425	PFAM Usg family protein
AM571_RS11240	COG1116	anion transmembrane transporter activity
AM571_RS11245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM571_RS11250	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM571_RS11255	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM571_RS11260	COG2084	Dehydrogenase
AM571_RS11270	COG1522	sequence-specific DNA binding
AM571_RS11275	COG1573	uracil-dna glycosylase
AM571_RS11285	COG2205	protein histidine kinase activity
AM571_RS11285	COG2202	Pas domain
AM571_RS11290	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AM571_RS11300	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AM571_RS11305	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AM571_RS11355	COG0842	Transport permease protein
AM571_RS11360	COG1131	(ABC) transporter
AM571_RS11375	COG2329	Antibiotic biosynthesis monooxygenase
AM571_RS11395	COG1607	acyl-coa hydrolase
AM571_RS11405	COG1028	Short-chain dehydrogenase reductase Sdr
AM571_RS11440	COG4178	(ABC) transporter
AM571_RS11460	COG3795	YCII-related domain
AM571_RS11480	COG0556	nucleotide-excision repair
AM571_RS11485	COG0484	heat shock protein binding
AM571_RS11495	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM571_RS11580	COG1028	Short-chain dehydrogenase reductase Sdr
AM571_RS11585	COG3842	ATPase activity
AM571_RS11600	COG1177	transmembrane transport
AM571_RS11610	COG1063	alcohol dehydrogenase
AM571_RS11645	COG0179	Fumarylacetoacetate (FAA) hydrolase
AM571_RS11655	COG0735	belongs to the Fur family
AM571_RS11660	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM571_RS11665	COG1121	(ABC) transporter
AM571_RS11685	COG0456	acetyltransferase
AM571_RS11690	COG3507	Belongs to the glycosyl hydrolase 43 family
AM571_RS11695	COG0667	Aldo Keto reductase
AM571_RS11700	COG0673	inositol 2-dehydrogenase activity
AM571_RS11720	COG0395	ABC-type sugar transport system, permease component
AM571_RS11725	COG1175	transmembrane transport
AM571_RS11740	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AM571_RS11770	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM571_RS11780	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AM571_RS11785	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AM571_RS11850	COG1492	cobalamin metabolic process
AM571_RS11870	COG0583	DNA-binding transcription factor activity
AM571_RS11895	COG0745	RESPONSE REGULATOR receiver
AM571_RS11900	COG0745	RESPONSE REGULATOR receiver
AM571_RS11905	COG0704	Plays a role in the regulation of phosphate uptake
AM571_RS11910	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AM571_RS11920	COG0573	inorganic phosphate transmembrane transporter activity
AM571_RS11925	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AM571_RS11930	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AM571_RS11945	COG3639	organic phosphonate transmembrane transporter activity
AM571_RS12100	COG2963	transposase activity
AM571_RS12105	COG3436	PFAM IS66 Orf2 family protein
AM571_RS12110	COG2433	Pfam Transposase IS66
AM571_RS12190	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AM571_RS12245	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM571_RS12280	COG0745	RESPONSE REGULATOR receiver
AM571_RS12290	COG3264	Mechanosensitive ion channel
AM571_RS12290	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AM571_RS12300	COG0745	RESPONSE REGULATOR receiver
AM571_RS12305	COG0477	Major facilitator Superfamily
AM571_RS12315	COG0697	spore germination
AM571_RS12375	COG1566	PFAM secretion protein HlyD family protein
AM571_RS12390	COG0628	permease
AM571_RS12435	COG0384	phenazine biosynthesis protein PhzF
AM571_RS12450	COG3842	ATPase activity
AM571_RS12455	COG4149	molybdate abc transporter
AM571_RS12465	COG0667	Aldo Keto reductase
AM571_RS12470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM571_RS12480	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AM571_RS12490	COG2207	Transcriptional regulator
AM571_RS12505	COG1064	alcohol dehydrogenase
AM571_RS12510	COG1252	NADH dehydrogenase
AM571_RS12515	COG1522	sequence-specific DNA binding
AM571_RS12520	COG1794	racemase activity, acting on amino acids and derivatives
AM571_RS12525	COG0456	acetyltransferase
AM571_RS12525	COG1846	Transcriptional regulator
AM571_RS12530	COG1309	transcriptional regulator
AM571_RS12535	COG2814	Major facilitator Superfamily
AM571_RS12540	COG1733	regulation of RNA biosynthetic process
AM571_RS12550	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AM571_RS12560	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AM571_RS12570	COG0488	(ABC) transporter
AM571_RS12625	COG0656	L-ascorbic acid biosynthetic process
AM571_RS12630	COG0440	acetolactate synthase activity
AM571_RS12635	COG0028	Belongs to the TPP enzyme family
AM571_RS12650	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AM571_RS12655	COG0560	Phosphoserine phosphatase
AM571_RS12675	COG0330	HflC and HflK could
AM571_RS12700	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AM571_RS12730	COG0277	FAD linked oxidase domain protein
AM571_RS12735	COG0667	Aldo Keto reductase
AM571_RS12740	COG0583	DNA-binding transcription factor activity
AM571_RS12745	COG3180	Ammonia monooxygenase
AM571_RS12765	COG2885	chlorophyll binding
AM571_RS12770	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AM571_RS12775	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM571_RS12785	COG0210	DNA helicase
AM571_RS12810	COG1335	isochorismatase
AM571_RS12830	COG0006	proline dipeptidase activity
AM571_RS12835	COG2264	protein methyltransferase activity
AM571_RS12845	COG1999	signal sequence binding
AM571_RS12850	COG0835	chemotaxis
AM571_RS12870	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AM571_RS12880	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM571_RS12890	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AM571_RS12895	COG0849	cell division
AM571_RS12900	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AM571_RS12905	COG1181	Belongs to the D-alanine--D-alanine ligase family
AM571_RS12915	COG0477	Major facilitator Superfamily
AM571_RS12920	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AM571_RS12925	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AM571_RS12930	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AM571_RS12940	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AM571_RS12945	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AM571_RS12955	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AM571_RS12970	COG0275	rRNA processing
AM571_RS12975	COG2001	Belongs to the MraZ family
AM571_RS12995	COG3023	N-Acetylmuramoyl-L-alanine amidase
AM571_RS13010	COG1280	lysine exporter protein (LysE YggA)
AM571_RS13045	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AM571_RS13050	COG2226	methyltransferase
AM571_RS13065	COG2267	carboxylic ester hydrolase activity
AM571_RS13070	COG0697	spore germination
AM571_RS13075	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AM571_RS13080	COG0028	Belongs to the TPP enzyme family
AM571_RS13085	COG0251	oxidation-reduction process
AM571_RS13100	COG1376	ErfK ybiS ycfS ynhG family protein
AM571_RS13105	COG1192	Involved in chromosome partitioning
AM571_RS13120	COG0174	glutamine synthetase
AM571_RS13155	COG3842	ATPase activity
AM571_RS13175	COG0673	inositol 2-dehydrogenase activity
AM571_RS13180	COG0395	ABC-type sugar transport system, permease component
AM571_RS13185	COG1175	transmembrane transport
AM571_RS13195	COG2971	BadF BadG BcrA BcrD
AM571_RS13200	COG2188	Transcriptional regulator
AM571_RS13215	COG4702	Belongs to the UPF0303 family
AM571_RS13230	COG2968	Membrane
AM571_RS13260	COG0432	Pfam Uncharacterised protein family UPF0047
AM571_RS13265	COG5507	3-demethylubiquinone-9 3-methyltransferase
AM571_RS13280	COG3448	diguanylate cyclase activity
AM571_RS13280	COG4175	Glycine betaine
AM571_RS13290	COG0697	spore germination
AM571_RS13295	COG1917	Cupin 2, conserved barrel domain protein
AM571_RS13295	COG2207	Transcriptional regulator
AM571_RS13310	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM571_RS13315	COG1063	alcohol dehydrogenase
AM571_RS13320	COG0156	8-amino-7-oxononanoate synthase activity
AM571_RS13325	COG0514	ATP-dependent DNA helicase (RecQ)
AM571_RS13330	COG0358	DNA primase activity
AM571_RS13350	COG0505	Belongs to the CarA family
AM571_RS13360	COG0534	Mate efflux family protein
AM571_RS13370	COG2321	neutral zinc metallopeptidase
AM571_RS13375	COG1063	alcohol dehydrogenase
AM571_RS13380	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AM571_RS13390	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AM571_RS13405	COG1522	sequence-specific DNA binding
AM571_RS13410	COG0492	ferredoxin-NADP+ reductase activity
AM571_RS13415	COG0583	DNA-binding transcription factor activity
AM571_RS13425	COG1902	pentaerythritol trinitrate reductase activity
AM571_RS13455	COG2133	pyrroloquinoline quinone binding
AM571_RS13465	COG1278	Cold shock
AM571_RS13475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM571_RS13490	COG1846	Transcriptional regulator
AM571_RS13495	COG0745	RESPONSE REGULATOR receiver
AM571_RS13500	COG2205	protein histidine kinase activity
AM571_RS13510	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM571_RS13530	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AM571_RS13555	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AM571_RS13570	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AM571_RS13575	COG3300	MHYT domain
AM571_RS13575	COG5001	Diguanylate cyclase
AM571_RS13585	COG0193	aminoacyl-tRNA hydrolase activity
AM571_RS13600	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AM571_RS13605	COG0012	GTP binding
AM571_RS13620	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AM571_RS13625	COG2857	Cytochrome c1
AM571_RS13625	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AM571_RS13640	COG1132	(ABC) transporter
AM571_RS13650	COG1132	(ABC) transporter
AM571_RS13655	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AM571_RS13660	COG1283	sodium-dependent phosphate transmembrane transporter activity
AM571_RS13670	COG0408	coproporphyrinogen oxidase activity
AM571_RS13685	COG0617	tRNA 3'-terminal CCA addition
AM571_RS13700	COG0714	Associated with various cellular activities
AM571_RS13725	COG0435	Glutathione S-transferase
AM571_RS13760	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AM571_RS13765	COG3135	benzoate transporter
AM571_RS13770	COG3344	reverse transcriptase
AM571_RS13775	COG0740	serine-type endopeptidase activity
AM571_RS13785	COG3416	Protein conserved in bacteria
AM571_RS13790	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AM571_RS13795	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AM571_RS13810	COG0512	Glutamine amidotransferase of anthranilate synthase
AM571_RS13810	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AM571_RS13830	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AM571_RS13835	COG2197	response regulator
AM571_RS13850	COG1435	thymidine kinase activity
AM571_RS13865	COG3448	diguanylate cyclase activity
AM571_RS13865	COG4175	Glycine betaine
AM571_RS13880	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AM571_RS13895	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AM571_RS13900	COG0366	Alpha amylase catalytic
AM571_RS13910	COG0601	transmembrane transport
AM571_RS13915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM571_RS13925	COG4608	Belongs to the ABC transporter superfamily
AM571_RS13940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM571_RS13955	COG1846	Transcriptional regulator
AM571_RS13965	COG1160	GTP binding
AM571_RS13985	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AM571_RS13995	COG0024	Methionine aminopeptidase
AM571_RS14010	COG4941	Belongs to the sigma-70 factor family
AM571_RS14015	COG3795	YCII-related domain
AM571_RS14025	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AM571_RS14030	COG1028	Short-chain dehydrogenase reductase Sdr
AM571_RS14040	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AM571_RS14055	COG0583	DNA-binding transcription factor activity
AM571_RS14070	COG0402	S-adenosylhomocysteine deaminase activity
AM571_RS14120	COG2095	MarC family integral membrane protein
AM571_RS14130	COG2351	hydroxyisourate hydrolase activity
AM571_RS14135	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
AM571_RS14150	COG4266	Belongs to the allantoicase family
AM571_RS14155	COG3648	Uricase
AM571_RS14155	COG3195	allantoin biosynthetic process
AM571_RS14190	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AM571_RS14190	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM571_RS14195	COG5002	protein histidine kinase activity
AM571_RS14195	COG2205	protein histidine kinase activity
AM571_RS14195	COG0784	Response regulator, receiver
AM571_RS14205	COG0513	Belongs to the DEAD box helicase family
AM571_RS14210	COG1032	radical SAM domain protein
AM571_RS14220	COG0673	inositol 2-dehydrogenase activity
AM571_RS14250	COG4214	carbohydrate transport
AM571_RS14260	COG1012	belongs to the aldehyde dehydrogenase family
AM571_RS14265	COG0129	dihydroxy-acid dehydratase activity
AM571_RS14305	COG2308	Evidence 4 Homologs of previously reported genes of
AM571_RS14315	COG4213	ABC transporter substrate-binding protein
AM571_RS14320	COG4214	carbohydrate transport
AM571_RS14325	COG1129	ABC transporter
AM571_RS14335	COG3415	Transposase
AM571_RS14335	COG2801	Transposase and inactivated derivatives
AM571_RS14345	COG0702	epimerase
AM571_RS14350	COG0583	DNA-binding transcription factor activity
AM571_RS14370	COG0798	PFAM Bile acid sodium symporter
AM571_RS14375	COG1393	Belongs to the ArsC family
AM571_RS14380	COG0431	NADPH-dependent FMN reductase
AM571_RS14390	COG0640	Transcriptional regulator
AM571_RS14410	COG1511	domain protein
AM571_RS14410	COG3264	Mechanosensitive ion channel
AM571_RS14435	COG2197	response regulator
AM571_RS14515	COG1596	polysaccharide export
AM571_RS14520	COG0438	transferase activity, transferring glycosyl groups
AM571_RS14525	COG0673	inositol 2-dehydrogenase activity
AM571_RS14530	COG2076	Multidrug Resistance protein
AM571_RS14540	COG2346	COG2346, Truncated hemoglobins
AM571_RS14555	COG2329	Antibiotic biosynthesis monooxygenase
AM571_RS14585	COG3720	iron ion transport
AM571_RS14590	COG4558	Periplasmic binding protein
AM571_RS14595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM571_RS14600	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AM571_RS14625	COG0784	Response regulator, receiver
AM571_RS14635	COG0493	'glutamate synthase
AM571_RS14645	COG2207	Transcriptional regulator
AM571_RS14655	COG0598	Magnesium transport protein CorA
AM571_RS14660	COG0604	alcohol dehydrogenase
AM571_RS14660	COG1028	Short-chain dehydrogenase reductase Sdr
AM571_RS14660	COG3321	synthase
AM571_RS14670	COG4251	negative regulation of phosphorylation
AM571_RS14675	COG1309	transcriptional regulator
AM571_RS14705	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM571_RS14710	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM571_RS14715	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM571_RS14730	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AM571_RS14735	COG0830	nickel cation binding
AM571_RS14740	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AM571_RS14745	COG3706	GGDEF domain
AM571_RS14750	COG0804	urea catabolic process
AM571_RS14755	COG1442	glycosyl transferase family 8
AM571_RS14760	COG3755	Protein conserved in bacteria
AM571_RS14765	COG0832	Belongs to the urease beta subunit family
AM571_RS14770	COG3813	Protein conserved in bacteria
AM571_RS14810	COG2198	Histidine kinase
AM571_RS14810	COG0784	Response regulator, receiver
AM571_RS14810	COG5002	protein histidine kinase activity
AM571_RS14815	COG0745	RESPONSE REGULATOR receiver
AM571_RS14830	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AM571_RS14835	COG0683	leucine binding
AM571_RS14860	COG0559	Belongs to the binding-protein-dependent transport system permease family
AM571_RS14885	COG1218	3'(2'),5'-bisphosphate nucleotidase
AM571_RS14945	COG0564	pseudouridine synthase activity
AM571_RS14950	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM571_RS14960	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AM571_RS14985	COG0346	lactoylglutathione lyase activity
AM571_RS14990	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AM571_RS14995	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AM571_RS15000	COG0662	Cupin 2, conserved barrel domain protein
AM571_RS15000	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AM571_RS15005	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AM571_RS15010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM571_RS15020	COG0129	dihydroxy-acid dehydratase activity
AM571_RS15030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM571_RS15045	COG1028	Short-chain dehydrogenase reductase Sdr
AM571_RS15055	COG2094	Belongs to the DNA glycosylase MPG family
AM571_RS15065	COG1566	PFAM secretion protein HlyD family protein
AM571_RS15085	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AM571_RS15090	COG3307	-O-antigen
AM571_RS15095	COG1596	polysaccharide export
AM571_RS15110	COG1215	transferase activity, transferring glycosyl groups
AM571_RS15115	COG0463	Glycosyl transferase, family 2
AM571_RS15120	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AM571_RS15125	COG2273	Hydrolase Family 16
AM571_RS15130	COG1215	transferase activity, transferring glycosyl groups
AM571_RS15135	COG1215	transferase activity, transferring glycosyl groups
AM571_RS15140	COG1215	transferase activity, transferring glycosyl groups
AM571_RS15145	COG0489	protein tyrosine kinase activity
AM571_RS15145	COG3206	protein involved in exopolysaccharide biosynthesis
AM571_RS15150	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AM571_RS15160	COG1959	2 iron, 2 sulfur cluster binding
AM571_RS15165	COG0583	DNA-binding transcription factor activity
AM571_RS15170	COG2186	Transcriptional regulator
AM571_RS15175	COG0747	negative chemotaxis
AM571_RS15190	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM571_RS15195	COG0444	Belongs to the ABC transporter superfamily
AM571_RS15205	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM571_RS15210	COG1063	alcohol dehydrogenase
AM571_RS15215	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AM571_RS15225	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AM571_RS15240	COG1733	regulation of RNA biosynthetic process
AM571_RS15255	COG1672	PFAM Archaeal ATPase
AM571_RS15255	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AM571_RS15265	COG0673	inositol 2-dehydrogenase activity
AM571_RS15270	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AM571_RS15285	COG2186	Transcriptional regulator
AM571_RS15305	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AM571_RS15310	COG1252	NADH dehydrogenase
AM571_RS15325	COG3220	belongs to the UPF0276 family
AM571_RS15340	COG1028	Short-chain dehydrogenase reductase Sdr
AM571_RS15345	COG0583	DNA-binding transcription factor activity
AM571_RS15355	COG2814	Major facilitator Superfamily
AM571_RS15370	COG1132	(ABC) transporter
AM571_RS15390	COG0438	transferase activity, transferring glycosyl groups
AM571_RS15420	COG1368	sulfuric ester hydrolase activity
AM571_RS15425	COG1028	Short-chain dehydrogenase reductase Sdr
AM571_RS15430	COG0156	8-amino-7-oxononanoate synthase activity
AM571_RS15435	COG0604	alcohol dehydrogenase
AM571_RS15435	COG1028	Short-chain dehydrogenase reductase Sdr
AM571_RS15435	COG3321	synthase
AM571_RS15465	COG2433	Pfam Transposase IS66
AM571_RS15470	COG3436	PFAM IS66 Orf2 family protein
AM571_RS15475	COG2963	transposase activity
AM571_RS15530	COG0765	amino acid transport
AM571_RS15535	COG4215	(ABC) transporter
AM571_RS15545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM571_RS15585	COG3436	PFAM IS66 Orf2 family protein
AM571_RS15590	COG2963	transposase activity
AM571_RS15595	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AM571_RS15640	COG1396	sequence-specific DNA binding
AM571_RS15665	COG3505	Type IV secretory pathway VirD4
AM571_RS15680	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AM571_RS15680	COG1672	PFAM Archaeal ATPase
AM571_RS15695	COG3360	Dodecin
AM571_RS15750	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
AM571_RS15755	COG2948	multi-organism process
AM571_RS15760	COG3504	Conjugal transfer protein
AM571_RS15765	COG3736	Type IV secretory pathway, component VirB8
AM571_RS15775	COG3704	protein secretion by the type IV secretion system
AM571_RS15790	COG3451	type IV secretory pathway VirB4
AM571_RS15795	COG3702	type iv secretory pathway
AM571_RS15800	COG3838	Conjugal transfer protein Trbc
AM571_RS15820	COG1278	Cold shock
AM571_RS15830	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM571_RS15855	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM571_RS15865	COG1063	alcohol dehydrogenase
AM571_RS15870	COG0673	inositol 2-dehydrogenase activity
AM571_RS15885	COG5654	RES domain protein
AM571_RS15890	COG2188	Transcriptional regulator
AM571_RS15895	COG1653	transport
AM571_RS15920	COG0673	inositol 2-dehydrogenase activity
AM571_RS15930	COG0395	ABC-type sugar transport system, permease component
AM571_RS15940	COG3842	ATPase activity
AM571_RS15975	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM571_RS16030	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AM571_RS16035	COG1741	Belongs to the pirin family
AM571_RS16055	COG1335	isochorismatase
AM571_RS16060	COG0583	DNA-binding transcription factor activity
AM571_RS16075	COG0300	oxidoreductase activity
AM571_RS16080	COG0583	DNA-binding transcription factor activity
AM571_RS16095	COG0667	Aldo Keto reductase
AM571_RS16100	COG0583	DNA-binding transcription factor activity
AM571_RS16130	COG4372	Transposase
AM571_RS16135	COG3436	PFAM IS66 Orf2 family protein
AM571_RS16140	COG2963	transposase activity
AM571_RS16185	COG1187	pseudouridine synthase activity
AM571_RS16195	COG0471	metal ion transport
AM571_RS16195	COG3273	potassium ion transport
AM571_RS16200	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AM571_RS16205	COG1309	transcriptional regulator
AM571_RS16210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM571_RS16215	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM571_RS16225	COG1609	Transcriptional regulator
AM571_RS16235	COG1176	ABC-type spermidine putrescine transport system, permease component I
AM571_RS16240	COG1177	transmembrane transport
AM571_RS16255	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AM571_RS16260	COG1473	amidohydrolase
AM571_RS16290	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AM571_RS16340	COG0598	Magnesium transport protein CorA
AM571_RS16365	COG1484	DNA-dependent DNA replication
AM571_RS16370	COG4584	PFAM Integrase catalytic
AM571_RS16380	COG2801	Transposase and inactivated derivatives
AM571_RS16380	COG3415	Transposase
AM571_RS16400	COG1475	DNA binding
AM571_RS16505	COG4373	Mu-like prophage FluMu protein gp28
AM571_RS16510	COG4383	Mu-like prophage protein gp29
AM571_RS16515	COG2369	cell adhesion
AM571_RS16545	COG4397	Mu-like prophage major head subunit gpT
AM571_RS16665	COG3685	Protein conserved in bacteria
AM571_RS16685	COG0482	sulfurtransferase activity
AM571_RS16690	COG0668	transmembrane transport
AM571_RS16710	COG0789	Transcriptional regulator
AM571_RS16725	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AM571_RS16745	COG1845	cytochrome c oxidase, subunit III
AM571_RS16750	COG1845	cytochrome c oxidase, subunit III
AM571_RS16755	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AM571_RS16760	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AM571_RS16770	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AM571_RS16775	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM571_RS16780	COG0037	tRNA processing
AM571_RS16790	COG2885	chlorophyll binding
AM571_RS16795	COG0823	Involved in the tonB-independent uptake of proteins
AM571_RS16815	COG0824	Thioesterase
AM571_RS16840	COG1692	metallophosphoesterase
AM571_RS16855	COG0217	transcriptional regulatory protein
AM571_RS16860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM571_RS16865	COG0840	transmembrane signaling receptor activity
AM571_RS16870	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AM571_RS16885	COG0632	four-way junction helicase activity
AM571_RS16890	COG2255	four-way junction helicase activity
AM571_RS16895	COG1408	metallophosphoesterase
AM571_RS16905	COG2318	DinB family
AM571_RS16920	COG0668	transmembrane transport
AM571_RS16925	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AM571_RS16940	COG2814	Major facilitator Superfamily
AM571_RS16945	COG0583	DNA-binding transcription factor activity
AM571_RS16980	COG0126	phosphoglycerate kinase activity
AM571_RS16985	COG3588	fructose-bisphosphate aldolase
AM571_RS16990	COG0384	phenazine biosynthesis protein PhzF
AM571_RS17010	COG0254	rRNA binding
AM571_RS17015	COG1132	(ABC) transporter
AM571_RS17030	COG3422	double-strand break repair
AM571_RS17050	COG0483	inositol monophosphate 1-phosphatase activity
AM571_RS17070	COG0640	Transcriptional regulator
AM571_RS17085	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AM571_RS17090	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AM571_RS17095	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AM571_RS17100	COG0457	Tetratricopeptide repeat
AM571_RS17105	COG0596	Alpha beta hydrolase
AM571_RS17105	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM571_RS17130	COG0583	DNA-binding transcription factor activity
AM571_RS17135	COG1942	4-Oxalocrotonate Tautomerase
AM571_RS17145	COG1280	lysine exporter protein (LysE YggA)
AM571_RS17150	COG0469	pyruvate kinase activity
AM571_RS17170	COG3750	Belongs to the UPF0335 family
AM571_RS17175	COG3108	Peptidase M15
AM571_RS17205	COG5310	Homospermidine synthase
AM571_RS17215	COG0737	Belongs to the 5'-nucleotidase family
AM571_RS17220	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AM571_RS17225	COG0330	HflC and HflK could
AM571_RS17245	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AM571_RS17250	COG2951	lytic endotransglycosylase activity
AM571_RS17265	COG0067	glutamate synthase
AM571_RS17265	COG0070	glutamate synthase
AM571_RS17265	COG0069	glutamate synthase activity
AM571_RS17290	COG0071	Belongs to the small heat shock protein (HSP20) family
AM571_RS17335	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AM571_RS17335	COG2755	lipolytic protein G-D-S-L family
AM571_RS17355	COG1285	pathogenesis
AM571_RS17420	COG2308	Evidence 4 Homologs of previously reported genes of
AM571_RS17420	COG2307	Protein conserved in bacteria
AM571_RS17435	COG0058	SHG alpha-glucan phosphorylase activity
AM571_RS17440	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AM571_RS17445	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AM571_RS17450	COG0297	glycogen (starch) synthase activity
AM571_RS17455	COG0033	Phosphoglucomutase
AM571_RS17460	COG1523	belongs to the glycosyl hydrolase 13 family
AM571_RS17475	COG0446	pyridine nucleotide-disulphide oxidoreductase
AM571_RS17475	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AM571_RS17485	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM571_RS17505	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AM571_RS17515	COG1278	Cold shock
AM571_RS17520	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AM571_RS17570	COG5001	Diguanylate cyclase
AM571_RS17585	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AM571_RS17590	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AM571_RS17605	COG1609	Transcriptional regulator
AM571_RS17610	COG1846	Transcriptional regulator
AM571_RS17620	COG0523	cobalamin synthesis protein
AM571_RS17640	COG0456	acetyltransferase
AM571_RS17650	COG0583	DNA-binding transcription factor activity
AM571_RS17680	COG0800	Aldolase
AM571_RS17685	COG2954	triphosphatase activity
AM571_RS17695	COG1054	Belongs to the UPF0176 family
AM571_RS17700	COG3300	MHYT domain
AM571_RS17700	COG5001	Diguanylate cyclase
AM571_RS17705	COG1464	Belongs to the NlpA lipoprotein family
AM571_RS17710	COG2011	ABC-type metal ion transport system permease component
AM571_RS17715	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AM571_RS17725	COG0673	inositol 2-dehydrogenase activity
AM571_RS17735	COG1879	ABC-type sugar transport system periplasmic component
AM571_RS17740	COG1172	Belongs to the binding-protein-dependent transport system permease family
AM571_RS17745	COG1129	ABC transporter
AM571_RS17750	COG1609	Transcriptional regulator
AM571_RS17755	COG2115	Belongs to the xylose isomerase family
AM571_RS17760	COG1070	Carbohydrate kinase
AM571_RS17765	COG1609	Transcriptional regulator
AM571_RS17780	COG1309	transcriptional regulator
AM571_RS17790	COG1253	flavin adenine dinucleotide binding
AM571_RS17795	COG0471	metal ion transport
AM571_RS17795	COG3273	potassium ion transport
AM571_RS17800	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AM571_RS17805	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AM571_RS17815	COG0583	DNA-binding transcription factor activity
AM571_RS17820	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AM571_RS17825	COG3842	ATPase activity
AM571_RS17830	COG1176	ABC-type spermidine putrescine transport system, permease component I
AM571_RS17835	COG1177	transmembrane transport
AM571_RS17855	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AM571_RS17905	COG0395	ABC-type sugar transport system, permease component
AM571_RS17910	COG1175	transmembrane transport
AM571_RS17940	COG1940	carbohydrate kinase activity
AM571_RS17960	COG1764	response to oxidative stress
AM571_RS17965	COG4948	Mandelate Racemase Muconate Lactonizing
AM571_RS17975	COG1028	Short-chain dehydrogenase reductase Sdr
AM571_RS17980	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AM571_RS17995	COG3842	ATPase activity
AM571_RS18000	COG0395	ABC-type sugar transport system, permease component
AM571_RS18005	COG1175	transmembrane transport
AM571_RS18010	COG1653	transport
AM571_RS18020	COG0392	lysyltransferase activity
AM571_RS18025	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM571_RS18045	COG0395	ABC-type sugar transport system, permease component
AM571_RS18055	COG3842	ATPase activity
AM571_RS18100	COG4191	Histidine kinase
AM571_RS18105	COG4566	intracellular signal transduction
AM571_RS18110	COG4566	intracellular signal transduction
AM571_RS18125	COG3395	kinase activity
AM571_RS18130	COG3622	Belongs to the hyi family
AM571_RS18135	COG2084	Dehydrogenase
AM571_RS18145	COG1609	Transcriptional regulator
AM571_RS18150	COG4178	(ABC) transporter
AM571_RS18155	COG0517	IMP dehydrogenase activity
AM571_RS18155	COG0617	tRNA 3'-terminal CCA addition
AM571_RS18155	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AM571_RS18160	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AM571_RS18165	COG3459	Glycosyltransferase 36 associated
AM571_RS18175	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AM571_RS18210	COG0387	Pfam Sodium calcium exchanger
AM571_RS18265	COG1846	Transcriptional regulator
AM571_RS18295	COG0297	glycogen (starch) synthase activity
AM571_RS18340	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AM571_RS18345	COG3842	ATPase activity
AM571_RS18350	COG0395	ABC-type sugar transport system, permease component
AM571_RS18365	COG1309	transcriptional regulator
AM571_RS18385	COG0626	cystathionine gamma-synthase activity
AM571_RS18420	COG4372	Transposase
AM571_RS18425	COG3436	PFAM IS66 Orf2 family protein
AM571_RS18430	COG2963	transposase activity
AM571_RS18475	COG0542	response to heat
AM571_RS18490	COG2890	protein-(glutamine-N5) methyltransferase activity
AM571_RS18495	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AM571_RS18500	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
AM571_RS18505	COG0527	aspartate kinase activity
AM571_RS18515	COG2323	membrane
AM571_RS18530	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AM571_RS18540	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM571_RS18550	COG2226	methyltransferase
AM571_RS18565	COG0494	nUDIX hydrolase
AM571_RS18570	COG0456	acetyltransferase
AM571_RS18575	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AM571_RS18580	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM571_RS18585	COG0653	protein targeting
AM571_RS18600	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AM571_RS18605	COG0667	Aldo Keto reductase
AM571_RS18645	COG4651	solute:proton antiporter activity
AM571_RS18645	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AM571_RS18675	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AM571_RS18685	COG0300	oxidoreductase activity
AM571_RS18710	COG2086	electron transfer activity
AM571_RS18715	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AM571_RS18720	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM571_RS18725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AM571_RS18730	COG0165	Argininosuccinate lyase
AM571_RS18765	COG2884	Cell division ATP-binding protein ftsE
AM571_RS18785	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AM571_RS18795	COG0287	Prephenate dehydrogenase
AM571_RS18800	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AM571_RS18805	COG2226	methyltransferase
AM571_RS18810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM571_RS18830	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AM571_RS18870	COG4536	flavin adenine dinucleotide binding
AM571_RS18875	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AM571_RS18880	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AM571_RS18885	COG4974	Belongs to the 'phage' integrase family
AM571_RS18890	COG0825	malonyl-CoA metabolic process
AM571_RS18895	COG3034	peptidoglycan biosynthetic process
AM571_RS18905	COG0523	cobalamin synthesis protein
AM571_RS18910	COG1686	Belongs to the peptidase S11 family
AM571_RS18915	COG1473	amidohydrolase
AM571_RS18930	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AM571_RS18945	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AM571_RS18955	COG1335	isochorismatase
AM571_RS18960	COG1917	Cupin 2, conserved barrel domain protein
AM571_RS18960	COG4977	sequence-specific DNA binding
AM571_RS18965	COG2207	Transcriptional regulator
AM571_RS18975	COG0583	DNA-binding transcription factor activity
AM571_RS18980	COG0346	lactoylglutathione lyase activity
AM571_RS18985	COG0400	carboxylic ester hydrolase activity
AM571_RS18990	COG2719	SpoVR family
AM571_RS18995	COG2718	Belongs to the UPF0229 family
AM571_RS19000	COG2766	serine protein kinase
AM571_RS19015	COG2823	Periplasmic or secreted lipoprotein
AM571_RS19025	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AM571_RS19030	COG0156	8-amino-7-oxononanoate synthase activity
AM571_RS19070	COG0010	Belongs to the arginase family
AM571_RS19075	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AM571_RS19080	COG0835	chemotaxis
AM571_RS19090	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AM571_RS19095	COG3383	formate dehydrogenase (NAD+) activity
AM571_RS19110	COG0583	DNA-binding transcription factor activity
AM571_RS19115	COG0640	Transcriptional regulator
AM571_RS19120	COG1028	Short-chain dehydrogenase reductase Sdr
AM571_RS19130	COG0789	Transcriptional regulator
AM571_RS19145	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AM571_RS19155	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AM571_RS19160	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AM571_RS19165	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AM571_RS19170	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AM571_RS19190	COG4974	Belongs to the 'phage' integrase family
AM571_RS19205	COG1280	lysine exporter protein (LysE YggA)
AM571_RS19210	COG1028	Short-chain dehydrogenase reductase Sdr
AM571_RS19220	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM571_RS19235	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AM571_RS19240	COG0045	succinate-CoA ligase (ADP-forming) activity
AM571_RS19245	COG0039	L-malate dehydrogenase activity
AM571_RS19250	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AM571_RS19255	COG2845	Protein of unknown function (DUF459)
AM571_RS19300	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AM571_RS19305	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AM571_RS19310	COG0181	hydroxymethylbilane synthase activity
AM571_RS19345	COG1872	DUF167
AM571_RS19350	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AM571_RS19360	COG1217	gtp-binding protein TYPA
AM571_RS19370	COG0339	signal peptide processing
AM571_RS19385	COG0137	argininosuccinate synthase activity
AM571_RS19400	COG0410	ABC transporter
AM571_RS19405	COG4120	Belongs to the binding-protein-dependent transport system permease family
AM571_RS19415	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AM571_RS19430	COG2154	pterin-4-alpha-carbinolamine dehydratase
AM571_RS19435	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AM571_RS19445	COG4181	ATPase activity
AM571_RS19455	COG0670	Belongs to the BI1 family
AM571_RS19475	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AM571_RS19480	COG4133	protoheme IX ABC transporter activity
AM571_RS19485	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AM571_RS19490	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AM571_RS19510	COG2917	probably involved in intracellular septation
AM571_RS19515	COG0552	protein localization to endoplasmic reticulum
AM571_RS19520	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AM571_RS19525	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AM571_RS19530	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AM571_RS19535	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AM571_RS19540	COG0287	Prephenate dehydrogenase
AM571_RS19540	COG1605	Chorismate mutase
AM571_RS19545	COG0228	four-way junction DNA binding
AM571_RS19550	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AM571_RS19555	COG0336	Belongs to the RNA methyltransferase TrmD family
AM571_RS19560	COG0335	large ribosomal subunit rRNA binding
AM571_RS19570	COG0765	amino acid transport
AM571_RS19575	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AM571_RS19585	COG0656	L-ascorbic acid biosynthetic process
AM571_RS19595	COG0745	RESPONSE REGULATOR receiver
AM571_RS19610	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AM571_RS19615	COG1674	ftsk spoiiie
AM571_RS19620	COG0004	ammonium transporteR
AM571_RS19625	COG0347	Belongs to the P(II) protein family
AM571_RS19630	COG1946	Acyl-CoA thioesterase
AM571_RS19635	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM571_RS19640	COG2835	tetraacyldisaccharide 4'-kinase activity
AM571_RS19650	COG3118	belongs to the thioredoxin family
AM571_RS19670	COG3842	ATPase activity
AM571_RS19685	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AM571_RS19690	COG1012	belongs to the aldehyde dehydrogenase family
AM571_RS19695	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM571_RS19700	COG5383	Protein conserved in bacteria
AM571_RS19720	COG1216	Glycosyl transferase, family 2
AM571_RS19745	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AM571_RS19755	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AM571_RS19770	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AM571_RS19775	COG4821	SIS domain
AM571_RS19780	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AM571_RS19785	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AM571_RS19790	COG2188	Transcriptional regulator
AM571_RS19800	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AM571_RS19805	COG4178	(ABC) transporter
AM571_RS19810	COG0488	(ABC) transporter
AM571_RS19830	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
AM571_RS19840	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM571_RS19845	COG1329	Transcriptional regulator
AM571_RS19850	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AM571_RS19880	COG1028	Short-chain dehydrogenase reductase Sdr
AM571_RS19885	COG0183	Belongs to the thiolase family
AM571_RS19890	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
AM571_RS19900	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AM571_RS19910	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AM571_RS19915	COG0142	geranyltranstransferase activity
AM571_RS19920	COG3177	Filamentation induced by cAMP protein fic
AM571_RS19930	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AM571_RS19935	COG2223	nitrite transmembrane transporter activity
AM571_RS19945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM571_RS19950	COG0765	amino acid transport
AM571_RS19955	COG1126	abc transporter atp-binding protein
AM571_RS19970	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AM571_RS19980	COG1132	(ABC) transporter
AM571_RS20000	COG3459	Glycosyltransferase 36 associated
AM571_RS20010	COG4608	Belongs to the ABC transporter superfamily
AM571_RS20015	COG0444	Belongs to the ABC transporter superfamily
AM571_RS20020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM571_RS20025	COG0601	transmembrane transport
AM571_RS20030	COG0747	negative chemotaxis
AM571_RS20060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM571_RS20070	COG1609	Transcriptional regulator
AM571_RS20075	COG0395	ABC-type sugar transport system, permease component
AM571_RS20080	COG1175	transmembrane transport
AM571_RS20090	COG3842	ATPase activity
AM571_RS20120	COG0583	DNA-binding transcription factor activity
AM571_RS20185	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AM571_RS20190	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AM571_RS20210	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AM571_RS20215	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AM571_RS20220	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AM571_RS20225	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AM571_RS20250	COG0596	Alpha beta hydrolase
AM571_RS20260	COG0583	DNA-binding transcription factor activity
AM571_RS20265	COG2205	protein histidine kinase activity
AM571_RS20290	COG0725	ABC transporter, periplasmic molybdate-binding protein
AM571_RS20295	COG4149	molybdate abc transporter
AM571_RS20300	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AM571_RS20310	COG0799	negative regulation of ribosome biogenesis
AM571_RS20315	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AM571_RS20325	COG0793	Belongs to the peptidase S41A family
AM571_RS20335	COG0494	nUDIX hydrolase
AM571_RS20340	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AM571_RS20365	COG0587	DNA-directed DNA polymerase activity
AM571_RS20400	COG0066	3-isopropylmalate dehydratase activity
AM571_RS20405	COG0473	3-isopropylmalate dehydrogenase activity
AM571_RS20410	COG0671	phosphoesterase, PA-phosphatase related
AM571_RS20420	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AM571_RS20430	COG0288	reversible hydration of carbon dioxide
AM571_RS20435	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AM571_RS20440	COG2902	Dehydrogenase
AM571_RS20445	COG2270	Major facilitator Superfamily
AM571_RS20450	COG0138	bifunctional purine biosynthesis protein purh
AM571_RS20465	COG0501	Belongs to the peptidase M48B family
AM571_RS20475	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AM571_RS20500	COG0495	leucyl-tRNA aminoacylation
AM571_RS20525	COG0357	Ribosomal RNA small subunit methyltransferase G
AM571_RS20530	COG0445	tRNA wobble uridine modification
AM571_RS20535	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AM571_RS20540	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AM571_RS20545	COG1981	membrane
AM571_RS20640	COG1074	ATP-dependent DNA helicase activity
AM571_RS20645	COG2887	Belongs to the helicase family. UvrD subfamily
AM571_RS20915	COG1079	Belongs to the binding-protein-dependent transport system permease family
AM571_RS21080	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AM571_RS21105	COG0539	negative regulation of cytoplasmic translation
AM571_RS21405	COG1674	ftsk spoiiie
AM571_RS21465	COG0837	glucose binding
AM571_RS21680	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AM571_RS22180	COG0583	DNA-binding transcription factor activity
AM571_RS22270	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AM571_RS22405	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AM571_RS22485	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AM571_RS23030	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM571_RS23325	COG1185	polyribonucleotide nucleotidyltransferase activity
AM571_RS23335	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AM571_RS23425	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AM571_RS23475	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AM571_RS23475	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AM571_RS23570	COG4174	ABC transporter (Permease)
AM571_RS23575	COG4239	(ABC) transporter, permease
AM571_RS23590	COG4172	Belongs to the ABC transporter superfamily
AM571_RS23595	COG4172	Belongs to the ABC transporter superfamily
AM571_RS24090	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AM571_RS24090	COG0519	Catalyzes the synthesis of GMP from XMP
AM571_RS24325	COG2807	transmembrane transport
AM571_RS24330	COG2807	transmembrane transport
AM571_RS24530	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AM571_RS24555	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AM571_RS24710	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AM571_RS25020	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AM571_RS25150	COG4372	Transposase
AM571_RS25240	COG0667	Aldo Keto reductase
AM571_RS25270	COG1079	Belongs to the binding-protein-dependent transport system permease family
AM571_RS25440	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AM571_RS25690	COG0443	Heat shock 70 kDa protein
AM571_RS25775	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AM571_RS25795	COG3626	phosphonate metabolism
AM571_RS26165	COG0481	GTPase activity
AM571_RS26420	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AM571_RS26420	COG0519	Catalyzes the synthesis of GMP from XMP
AM571_RS27000	COG0101	tRNA pseudouridine synthase activity
AM571_RS27130	COG3938	Belongs to the proline racemase family
AM571_RS27280	COG1732	Glycine betaine
AM571_RS27355	COG1028	Short-chain dehydrogenase reductase Sdr
AM571_RS27440	COG4964	Belongs to the GSP D family
AM571_RS27595	COG0167	dihydroorotate dehydrogenase activity
AM571_RS27615	COG0515	serine threonine protein kinase
AM571_RS27615	COG2815	serine threonine protein kinase
AM571_RS27740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM571_RS28135	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AM571_RS28160	COG2198	Histidine kinase
AM571_RS28160	COG0643	Histidine kinase
AM571_RS28690	COG0488	(ABC) transporter
AM571_RS29055	COG0277	FAD linked oxidase domain protein
AM571_RS29190	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AM571_RS29800	COG1196	nuclear chromosome segregation
AM571_RS29805	COG1196	nuclear chromosome segregation
AM571_RS29925	COG1012	belongs to the aldehyde dehydrogenase family
AM571_RS30135	COG0488	(ABC) transporter
AM571_RS30225	COG0730	response to heat
AM571_RS30405	COG2111	Na H antiporter
AM571_RS30405	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AM571_RS30515	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AM571_RS30940	COG0681	Belongs to the peptidase S26 family
AM571_RS31065	COG1611	Belongs to the LOG family
AM571_RS31145	COG0305	Participates in initiation and elongation during chromosome replication
AM571_RS31200	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AM571_RS31555	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AM571_RS31915	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AM571_RS32145	COG0557	exoribonuclease II activity
AM571_RS32255	COG1530	ribonuclease E activity
AM571_RS32255	COG1530	ribonuclease E activity
AM571_RS32340	COG0085	RNA polymerase activity
AM571_RS32695	COG0673	inositol 2-dehydrogenase activity
AM571_RS32725	COG1012	belongs to the aldehyde dehydrogenase family
AM571_RS32850	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AM571_RS32855	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AM571_RS33215	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AM571_RS33245	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AM571_RS33840	COG5000	phosphorelay sensor kinase activity
AM571_RS33880	COG1648	precorrin-2 dehydrogenase activity
AM571_RS33880	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AM571_RS34060	COG4166	transmembrane transport
AM571_RS34275	COG2801	Transposase and inactivated derivatives
AM571_RS34380	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AM571_RS34450	COG0149	triose-phosphate isomerase activity
AM571_RS34500	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AM571_RS34590	COG4770	biotin carboxylase activity
AM571_RS34595	COG4770	biotin carboxylase activity
AM571_RS34655	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AM571_RS34655	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AM571_RS34720	COG0719	Fe-S assembly protein
AM571_RS34755	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AM571_RS34840	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AM571_RS35425	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate