locus-tag	class	description
RHEC894_RS00010	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
RHEC894_RS00015	COG0424	maF-like protein
RHEC894_RS00020	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
RHEC894_RS00025	COG0237	dephospho-CoA kinase activity
RHEC894_RS00030	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
RHEC894_RS00035	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
RHEC894_RS00040	COG3030	protein affecting phage T7 exclusion by the F plasmid
RHEC894_RS00050	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
RHEC894_RS00080	COG0435	Glutathione S-transferase
RHEC894_RS00105	COG0135	phosphoribosylanthranilate isomerase activity
RHEC894_RS00110	COG0133	tryptophan synthase activity
RHEC894_RS00115	COG0159	tryptophan synthase activity
RHEC894_RS00120	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
RHEC894_RS00125	COG0285	dihydrofolate synthase activity
RHEC894_RS00135	COG1074	ATP-dependent DNA helicase activity
RHEC894_RS00140	COG2887	Belongs to the helicase family. UvrD subfamily
RHEC894_RS00145	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
RHEC894_RS00150	COG3178	'Phosphotransferase
RHEC894_RS00155	COG2205	protein histidine kinase activity
RHEC894_RS00160	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
RHEC894_RS00165	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
RHEC894_RS00170	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RHEC894_RS00170	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
RHEC894_RS00180	COG0642	Histidine kinase
RHEC894_RS00185	COG0745	RESPONSE REGULATOR receiver
RHEC894_RS00190	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
RHEC894_RS00205	COG1072	(Pantothenic acid kinase))
RHEC894_RS00210	COG0140	phosphoribosyl-ATP diphosphatase activity
RHEC894_RS00215	COG0107	imidazoleglycerol-phosphate synthase activity
RHEC894_RS00220	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
RHEC894_RS00235	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
RHEC894_RS00245	COG0131	Imidazoleglycerol-phosphate dehydratase
RHEC894_RS00250	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
RHEC894_RS00255	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
RHEC894_RS00265	COG2124	cytochrome p450
RHEC894_RS00270	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
RHEC894_RS00285	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
RHEC894_RS00295	COG1643	Atp-dependent helicase
RHEC894_RS00300	COG2423	ornithine cyclodeaminase activity
RHEC894_RS00355	COG2197	response regulator
RHEC894_RS00370	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
RHEC894_RS00375	COG1215	transferase activity, transferring glycosyl groups
RHEC894_RS00390	COG2182	Extracellular solute-binding protein
RHEC894_RS00410	COG0673	inositol 2-dehydrogenase activity
RHEC894_RS00425	COG0673	inositol 2-dehydrogenase activity
RHEC894_RS00430	COG1309	transcriptional regulator
RHEC894_RS00440	COG1175	transmembrane transport
RHEC894_RS00445	COG0395	ABC-type sugar transport system, permease component
RHEC894_RS00455	COG3842	ATPase activity
RHEC894_RS00470	COG0246	Mannitol dehydrogenase
RHEC894_RS00475	COG1904	glucuronate isomerase
RHEC894_RS00480	COG2900	Belongs to the SlyX family
RHEC894_RS00485	COG1012	belongs to the aldehyde dehydrogenase family
RHEC894_RS00490	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
RHEC894_RS00510	COG0539	negative regulation of cytoplasmic translation
RHEC894_RS00515	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
RHEC894_RS00545	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
RHEC894_RS00625	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
RHEC894_RS00635	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
RHEC894_RS00650	COG2813	Specifically methylates the guanine in position
RHEC894_RS00655	COG1185	polyribonucleotide nucleotidyltransferase activity
RHEC894_RS00660	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
RHEC894_RS00670	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
RHEC894_RS00675	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
RHEC894_RS00680	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
RHEC894_RS00695	COG0779	Required for maturation of 30S ribosomal subunits
RHEC894_RS00700	COG2814	Major facilitator Superfamily
RHEC894_RS00720	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
RHEC894_RS00725	COG2258	MOSC domain
RHEC894_RS00730	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
RHEC894_RS00735	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
RHEC894_RS00750	COG2816	NAD+ diphosphatase activity
RHEC894_RS00755	COG2378	regulation of single-species biofilm formation
RHEC894_RS00770	COG1605	Chorismate mutase
RHEC894_RS00770	COG0077	Prephenate dehydratase
RHEC894_RS00775	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
RHEC894_RS00780	COG3474	cytochrome
RHEC894_RS00785	COG0679	Auxin Efflux Carrier
RHEC894_RS00790	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RHEC894_RS00815	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
RHEC894_RS00820	COG1396	sequence-specific DNA binding
RHEC894_RS00830	COG0484	heat shock protein binding
RHEC894_RS00835	COG0443	Heat shock 70 kDa protein
RHEC894_RS00840	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
RHEC894_RS00855	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RHEC894_RS00860	COG5001	Diguanylate cyclase
RHEC894_RS00860	COG3300	MHYT domain
RHEC894_RS00875	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RHEC894_RS00875	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RHEC894_RS00880	COG1674	ftsk spoiiie
RHEC894_RS00885	COG1177	transmembrane transport
RHEC894_RS00890	COG1176	ABC-type spermidine putrescine transport system, permease component I
RHEC894_RS00895	COG3842	ATPase activity
RHEC894_RS00905	COG0583	DNA-binding transcription factor activity
RHEC894_RS00910	COG0456	acetyltransferase
RHEC894_RS00910	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
RHEC894_RS00915	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
RHEC894_RS00920	COG3454	Phosphonate metabolism
RHEC894_RS00925	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
RHEC894_RS00930	COG3639	organic phosphonate transmembrane transporter activity
RHEC894_RS00935	COG3639	organic phosphonate transmembrane transporter activity
RHEC894_RS00945	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
RHEC894_RS00955	COG4778	phosphonate C-P lyase system protein PhnL
RHEC894_RS00960	COG4107	phosphonate C-P lyase system protein PhnK
RHEC894_RS00965	COG3627	carbon phosphorus lyase activity
RHEC894_RS00970	COG3626	phosphonate metabolism
RHEC894_RS00975	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
RHEC894_RS00980	COG3624	Phosphonate C-P lyase system protein PhnG
RHEC894_RS00985	COG2188	Transcriptional regulator
RHEC894_RS00990	COG0588	phosphoglycerate mutase activity
RHEC894_RS00995	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
RHEC894_RS01000	COG1132	(ABC) transporter
RHEC894_RS01005	COG0837	glucose binding
RHEC894_RS01010	COG1803	Methylglyoxal synthase
RHEC894_RS01015	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
RHEC894_RS01020	COG4166	transmembrane transport
RHEC894_RS01025	COG4174	ABC transporter (Permease)
RHEC894_RS01030	COG4239	(ABC) transporter, permease
RHEC894_RS01035	COG4172	Belongs to the ABC transporter superfamily
RHEC894_RS01050	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
RHEC894_RS01070	COG4453	Protein conserved in bacteria
RHEC894_RS01085	COG1744	ABC transporter substrate-binding protein PnrA-like
RHEC894_RS01090	COG3845	ABC transporter
RHEC894_RS01095	COG1079	Belongs to the binding-protein-dependent transport system permease family
RHEC894_RS01100	COG1079	Belongs to the binding-protein-dependent transport system permease family
RHEC894_RS01110	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
RHEC894_RS01115	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
RHEC894_RS01120	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
RHEC894_RS01125	COG3577	Aspartyl protease
RHEC894_RS01130	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
RHEC894_RS01135	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
RHEC894_RS01140	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
RHEC894_RS01175	COG4964	Belongs to the GSP D family
RHEC894_RS01205	COG1280	lysine exporter protein (LysE YggA)
RHEC894_RS01215	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
RHEC894_RS01230	COG0154	amidase activity
RHEC894_RS01235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RHEC894_RS01245	COG0747	negative chemotaxis
RHEC894_RS01265	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
RHEC894_RS01275	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
RHEC894_RS01285	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
RHEC894_RS01315	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
RHEC894_RS01320	COG1715	Restriction endonuclease
RHEC894_RS01370	COG0481	GTPase activity
RHEC894_RS01400	COG2137	regulation of response to DNA damage stimulus
RHEC894_RS01425	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
RHEC894_RS01425	COG0596	Alpha beta hydrolase
RHEC894_RS01430	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
RHEC894_RS01435	COG0291	Belongs to the bacterial ribosomal protein bL35 family
RHEC894_RS01440	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
RHEC894_RS01445	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
RHEC894_RS01450	COG0072	phenylalanine-tRNA ligase activity
RHEC894_RS01450	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RHEC894_RS01470	COG3685	Protein conserved in bacteria
RHEC894_RS01480	COG0456	acetyltransferase
RHEC894_RS01515	COG1570	exodeoxyribonuclease VII activity
RHEC894_RS01520	COG1846	Transcriptional regulator
RHEC894_RS01525	COG0697	spore germination
RHEC894_RS01530	COG2309	aminopeptidase activity
RHEC894_RS01535	COG0625	glutathione transferase activity
RHEC894_RS01545	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
RHEC894_RS01550	COG1393	Belongs to the ArsC family
RHEC894_RS01570	COG4221	oxidoreductase activity
RHEC894_RS01580	COG0583	DNA-binding transcription factor activity
RHEC894_RS01585	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
RHEC894_RS01590	COG2207	Transcriptional regulator
RHEC894_RS01595	COG1881	PFAM PEBP family protein
RHEC894_RS01605	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
RHEC894_RS01615	COG0698	ribose 5-phosphate isomerase
RHEC894_RS01620	COG0518	GMP synthase (glutamine-hydrolyzing) activity
RHEC894_RS01620	COG0519	Catalyzes the synthesis of GMP from XMP
RHEC894_RS01670	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
RHEC894_RS01680	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
RHEC894_RS01690	COG1968	undecaprenyl-diphosphatase activity
RHEC894_RS01705	COG0284	orotidine-5'-phosphate decarboxylase activity
RHEC894_RS01715	COG3963	phosphatidate phosphatase activity
RHEC894_RS01735	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
RHEC894_RS01740	COG0792	nuclease activity
RHEC894_RS01750	COG1609	Transcriptional regulator
RHEC894_RS01760	COG1129	ABC transporter
RHEC894_RS01765	COG1172	Belongs to the binding-protein-dependent transport system permease family
RHEC894_RS01770	COG0189	ligase activity
RHEC894_RS01785	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RHEC894_RS01795	COG0783	Belongs to the Dps family
RHEC894_RS01800	COG0697	spore germination
RHEC894_RS01805	COG1522	sequence-specific DNA binding
RHEC894_RS01810	COG0756	dUTP diphosphatase activity
RHEC894_RS01815	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
RHEC894_RS01830	COG2807	transmembrane transport
RHEC894_RS01840	COG1741	Belongs to the pirin family
RHEC894_RS01850	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
RHEC894_RS01860	COG0583	DNA-binding transcription factor activity
RHEC894_RS01865	COG2814	Major facilitator Superfamily
RHEC894_RS01875	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
RHEC894_RS01900	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
RHEC894_RS01910	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
RHEC894_RS01915	COG2226	methyltransferase
RHEC894_RS01920	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
RHEC894_RS01925	COG1024	Enoyl-CoA hydratase
RHEC894_RS01930	COG0268	Binds directly to 16S ribosomal RNA
RHEC894_RS01935	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
RHEC894_RS01945	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RHEC894_RS01950	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
RHEC894_RS01960	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
RHEC894_RS01965	COG1420	regulation of RNA biosynthetic process
RHEC894_RS01970	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
RHEC894_RS01975	COG1957	nucleoside hydrolase
RHEC894_RS01980	COG0071	Belongs to the small heat shock protein (HSP20) family
RHEC894_RS01990	COG0220	tRNA (guanine-N7-)-methyltransferase activity
RHEC894_RS01995	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
RHEC894_RS02000	COG1396	sequence-specific DNA binding
RHEC894_RS02005	COG0815	Transfers the fatty acyl group on membrane lipoproteins
RHEC894_RS02010	COG4535	Mg2 and Co2 transporter CorC
RHEC894_RS02015	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
RHEC894_RS02020	COG1702	phosphate starvation-inducible protein PhoH
RHEC894_RS02025	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RHEC894_RS02050	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
RHEC894_RS02060	COG0180	Tryptophanyl-tRNA synthetase
RHEC894_RS02070	COG2852	Protein conserved in bacteria
RHEC894_RS02090	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
RHEC894_RS02095	COG0281	malic enzyme
RHEC894_RS02095	COG0280	phosphate acetyltransferase
RHEC894_RS02100	COG2207	Transcriptional regulator
RHEC894_RS02115	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
RHEC894_RS02125	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
RHEC894_RS02125	COG0116	Belongs to the methyltransferase superfamily
RHEC894_RS02150	COG0776	regulation of translation
RHEC894_RS02165	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
RHEC894_RS02170	COG1137	ATPase activity
RHEC894_RS02180	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
RHEC894_RS02185	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RHEC894_RS02190	COG0840	transmembrane signaling receptor activity
RHEC894_RS02195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RHEC894_RS02205	COG0242	peptide deformylase activity
RHEC894_RS02220	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
RHEC894_RS02225	COG0101	tRNA pseudouridine synthase activity
RHEC894_RS02235	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RHEC894_RS02240	COG2171	N-acyltransferase activity
RHEC894_RS02260	COG1032	radical SAM domain protein
RHEC894_RS02265	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
RHEC894_RS02265	COG2169	Transcriptional regulator
RHEC894_RS02275	COG1304	FMN binding
RHEC894_RS02290	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
RHEC894_RS02295	COG5484	DNA packaging
RHEC894_RS02305	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
RHEC894_RS02310	COG0218	Necessary for normal cell division and for the maintenance of normal septation
RHEC894_RS02315	COG0706	membrane insertase activity
RHEC894_RS02320	COG0594	ribonuclease P activity
RHEC894_RS02325	COG0230	Belongs to the bacterial ribosomal protein bL34 family
RHEC894_RS02345	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
RHEC894_RS02375	COG3668	Plasmid stabilization system
RHEC894_RS02385	COG1028	Short-chain dehydrogenase reductase Sdr
RHEC894_RS02390	COG0259	pyridoxamine-phosphate oxidase activity
RHEC894_RS02430	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
RHEC894_RS02435	COG1309	transcriptional regulator
RHEC894_RS02440	COG0667	Aldo Keto reductase
RHEC894_RS02445	COG3385	transposase activity
RHEC894_RS02455	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RHEC894_RS02460	COG3938	Belongs to the proline racemase family
RHEC894_RS02480	COG3300	MHYT domain
RHEC894_RS02480	COG5001	Diguanylate cyclase
RHEC894_RS02510	COG1072	(Pantothenic acid kinase))
RHEC894_RS02515	COG0418	dihydroorotase activity
RHEC894_RS02530	COG3385	transposase activity
RHEC894_RS02540	COG1309	transcriptional regulator
RHEC894_RS02545	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
RHEC894_RS02560	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
RHEC894_RS02565	COG0166	Belongs to the GPI family
RHEC894_RS02570	COG0318	PFAM AMP-dependent synthetase and ligase
RHEC894_RS02595	COG1174	glycine betaine transport
RHEC894_RS02600	COG1125	glycine betaine transport
RHEC894_RS02605	COG1174	glycine betaine transport
RHEC894_RS02610	COG1732	Glycine betaine
RHEC894_RS02620	COG0583	DNA-binding transcription factor activity
RHEC894_RS02625	COG3142	Participates in the control of copper homeostasis
RHEC894_RS02630	COG1063	alcohol dehydrogenase
RHEC894_RS02635	COG1172	Belongs to the binding-protein-dependent transport system permease family
RHEC894_RS02660	COG2721	sulfolactate sulfo-lyase activity
RHEC894_RS02670	COG4178	(ABC) transporter
RHEC894_RS02675	COG2814	Major facilitator Superfamily
RHEC894_RS02720	COG2326	polyphosphate kinase activity
RHEC894_RS02725	COG5002	protein histidine kinase activity
RHEC894_RS02730	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
RHEC894_RS02735	COG0573	inorganic phosphate transmembrane transporter activity
RHEC894_RS02745	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
RHEC894_RS02750	COG0704	Plays a role in the regulation of phosphate uptake
RHEC894_RS02755	COG0745	RESPONSE REGULATOR receiver
RHEC894_RS02765	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
RHEC894_RS02770	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
RHEC894_RS02775	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
RHEC894_RS02785	COG2967	ApaG domain
RHEC894_RS02795	COG0717	Belongs to the dCTP deaminase family
RHEC894_RS02815	COG0840	transmembrane signaling receptor activity
RHEC894_RS02820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RHEC894_RS02855	COG0167	dihydroorotate dehydrogenase activity
RHEC894_RS02860	COG0534	Mate efflux family protein
RHEC894_RS02885	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RHEC894_RS02890	COG1959	2 iron, 2 sulfur cluster binding
RHEC894_RS02900	COG1201	RNA secondary structure unwinding
RHEC894_RS02930	COG0730	response to heat
RHEC894_RS02950	COG1960	acyl-CoA dehydrogenase activity
RHEC894_RS02955	COG0183	Belongs to the thiolase family
RHEC894_RS02960	COG1024	Enoyl-CoA hydratase
RHEC894_RS02960	COG1250	3-hydroxyacyl-CoA dehydrogenase
RHEC894_RS02965	COG1278	Cold shock
RHEC894_RS03000	COG2205	protein histidine kinase activity
RHEC894_RS03000	COG0784	Response regulator, receiver
RHEC894_RS03000	COG2198	Histidine kinase
RHEC894_RS03005	COG1970	mechanosensitive ion channel activity
RHEC894_RS03010	COG0436	Aminotransferase
RHEC894_RS03020	COG5001	Diguanylate cyclase
RHEC894_RS03025	COG1024	Enoyl-CoA hydratase
RHEC894_RS03070	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
RHEC894_RS03080	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
RHEC894_RS03085	COG5328	Belongs to the UPF0262 family
RHEC894_RS03090	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
RHEC894_RS03095	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
RHEC894_RS03100	COG0424	maF-like protein
RHEC894_RS03105	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
RHEC894_RS03140	COG4251	negative regulation of phosphorylation
RHEC894_RS03140	COG5001	Diguanylate cyclase
RHEC894_RS03140	COG3706	GGDEF domain
RHEC894_RS03140	COG2203	Gaf domain
RHEC894_RS03145	COG3174	membrane
RHEC894_RS03160	COG0673	inositol 2-dehydrogenase activity
RHEC894_RS03185	COG1609	Transcriptional regulator
RHEC894_RS03190	COG3866	Pectate lyase
RHEC894_RS03200	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
RHEC894_RS03205	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
RHEC894_RS03235	COG0346	lactoylglutathione lyase activity
RHEC894_RS03240	COG4251	negative regulation of phosphorylation
RHEC894_RS03250	COG4251	negative regulation of phosphorylation
RHEC894_RS03260	COG2197	response regulator
RHEC894_RS03285	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
RHEC894_RS03285	COG4651	solute:proton antiporter activity
RHEC894_RS03295	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
RHEC894_RS03300	COG0840	transmembrane signaling receptor activity
RHEC894_RS03310	COG0745	RESPONSE REGULATOR receiver
RHEC894_RS03315	COG2198	Histidine kinase
RHEC894_RS03315	COG0643	Histidine kinase
RHEC894_RS03320	COG0835	chemotaxis
RHEC894_RS03325	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
RHEC894_RS03330	COG2201	protein-glutamate methylesterase activity
RHEC894_RS03335	COG0745	RESPONSE REGULATOR receiver
RHEC894_RS03340	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
RHEC894_RS03350	COG1766	The M ring may be actively involved in energy transduction
RHEC894_RS03355	COG2771	luxR family
RHEC894_RS03370	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
RHEC894_RS03375	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
RHEC894_RS03380	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
RHEC894_RS03385	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
RHEC894_RS03390	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
RHEC894_RS03395	COG4786	Flagellar basal body rod
RHEC894_RS03400	COG1157	protein secretion by the type III secretion system
RHEC894_RS03410	COG1815	bacterial-type flagellum-dependent cell motility
RHEC894_RS03415	COG1558	bacterial-type flagellum-dependent cell motility
RHEC894_RS03420	COG1677	Flagellar hook-basal body complex protein FliE
RHEC894_RS03425	COG4786	Flagellar basal body rod
RHEC894_RS03430	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
RHEC894_RS03435	COG1706	bacterial-type flagellum-dependent cell motility
RHEC894_RS03445	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
RHEC894_RS03455	COG1338	Plays a role in the flagellum-specific transport system
RHEC894_RS03465	COG1522	sequence-specific DNA binding
RHEC894_RS03490	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
RHEC894_RS03525	COG1749	Flagellar hook protein flgE
RHEC894_RS03545	COG5443	negative regulation of bacterial-type flagellum assembly
RHEC894_RS03550	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
RHEC894_RS03555	COG4794	Type iii secretion
RHEC894_RS03560	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
RHEC894_RS03565	COG1684	flagellar biosynthetic protein fliR
RHEC894_RS03590	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
RHEC894_RS03605	COG1609	Transcriptional regulator
RHEC894_RS03610	COG1653	transport
RHEC894_RS03615	COG1175	transmembrane transport
RHEC894_RS03620	COG0395	ABC-type sugar transport system, permease component
RHEC894_RS03625	COG0366	Alpha amylase catalytic
RHEC894_RS03630	COG3842	ATPase activity
RHEC894_RS03640	COG0129	dihydroxy-acid dehydratase activity
RHEC894_RS03645	COG0363	glucosamine-6-phosphate deaminase activity
RHEC894_RS03650	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
RHEC894_RS03655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RHEC894_RS03660	COG0174	glutamine synthetase
RHEC894_RS03665	COG2081	HI0933 family
RHEC894_RS03670	COG2972	Histidine kinase
RHEC894_RS03670	COG0840	transmembrane signaling receptor activity
RHEC894_RS03675	COG0840	transmembrane signaling receptor activity
RHEC894_RS03695	COG2224	Isocitrate lyase
RHEC894_RS03705	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
RHEC894_RS03710	COG3842	ATPase activity
RHEC894_RS03715	COG1176	ABC-type spermidine putrescine transport system, permease component I
RHEC894_RS03720	COG1177	transmembrane transport
RHEC894_RS03730	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RHEC894_RS03735	COG2205	protein histidine kinase activity
RHEC894_RS03770	COG1959	2 iron, 2 sulfur cluster binding
RHEC894_RS03775	COG0747	negative chemotaxis
RHEC894_RS03780	COG0601	transmembrane transport
RHEC894_RS03785	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RHEC894_RS03790	COG0444	Belongs to the ABC transporter superfamily
RHEC894_RS03795	COG4608	Belongs to the ABC transporter superfamily
RHEC894_RS03800	COG3265	gluconokinase activity
RHEC894_RS03805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RHEC894_RS03810	COG1755	Isoprenylcysteine carboxyl methyltransferase
RHEC894_RS03835	COG3300	MHYT domain
RHEC894_RS03835	COG5001	Diguanylate cyclase
RHEC894_RS03870	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RHEC894_RS03875	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
RHEC894_RS03885	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
RHEC894_RS03890	COG2089	acid synthase
RHEC894_RS03895	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
RHEC894_RS03910	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
RHEC894_RS03955	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RHEC894_RS03970	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
RHEC894_RS03980	COG0477	Major facilitator Superfamily
RHEC894_RS04000	COG0583	DNA-binding transcription factor activity
RHEC894_RS04005	COG1028	Short-chain dehydrogenase reductase Sdr
RHEC894_RS04025	COG0583	DNA-binding transcription factor activity
RHEC894_RS04050	COG0306	phosphate transporter
RHEC894_RS04065	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
RHEC894_RS04070	COG0583	DNA-binding transcription factor activity
RHEC894_RS04075	COG0277	FAD linked oxidase domain protein
RHEC894_RS04080	COG0277	FAD linked oxidase domain protein
RHEC894_RS04085	COG0247	lactate metabolic process
RHEC894_RS04100	COG1376	ErfK ybiS ycfS ynhG family protein
RHEC894_RS04100	COG1388	LysM domain
RHEC894_RS04105	COG1376	ErfK ybiS ycfS ynhG family protein
RHEC894_RS04110	COG2818	Glycosylase
RHEC894_RS04125	COG0667	Aldo Keto reductase
RHEC894_RS04145	COG0124	histidyl-tRNA synthetase
RHEC894_RS04150	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
RHEC894_RS04155	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
RHEC894_RS04160	COG2259	Doxx family
RHEC894_RS04165	COG0625	glutathione transferase activity
RHEC894_RS04180	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
RHEC894_RS04190	COG0196	riboflavin kinase activity
RHEC894_RS04205	COG0590	tRNA wobble adenosine to inosine editing
RHEC894_RS04210	COG1187	pseudouridine synthase activity
RHEC894_RS04215	COG0742	ribosomal rna small subunit methyltransferase
RHEC894_RS04230	COG0312	modulator of DNA gyrase
RHEC894_RS04235	COG0483	inositol monophosphate 1-phosphatase activity
RHEC894_RS04245	COG1519	Transferase
RHEC894_RS04255	COG1663	tetraacyldisaccharide 4'-kinase activity
RHEC894_RS04265	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
RHEC894_RS04270	COG0745	RESPONSE REGULATOR receiver
RHEC894_RS04275	COG5001	Diguanylate cyclase
RHEC894_RS04275	COG3300	MHYT domain
RHEC894_RS04285	COG3386	PFAM SMP-30 Gluconolaconase
RHEC894_RS04290	COG0800	Aldolase
RHEC894_RS04295	COG3734	2-keto-3-deoxy-galactonokinase
RHEC894_RS04300	COG1028	Short-chain dehydrogenase reductase Sdr
RHEC894_RS04305	COG1414	Transcriptional regulator
RHEC894_RS04310	COG2197	response regulator
RHEC894_RS04320	COG0489	protein tyrosine kinase activity
RHEC894_RS04330	COG0598	Magnesium transport protein CorA
RHEC894_RS04350	COG0356	it plays a direct role in the translocation of protons across the membrane
RHEC894_RS04360	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
RHEC894_RS04365	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
RHEC894_RS04370	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
RHEC894_RS04395	COG0521	Mo-molybdopterin cofactor biosynthetic process
RHEC894_RS04400	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
RHEC894_RS04410	COG0142	geranyltranstransferase activity
RHEC894_RS04425	COG1914	H( )-stimulated, divalent metal cation uptake system
RHEC894_RS04440	COG0752	glycyl-tRNA synthetase alpha subunit
RHEC894_RS04445	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
RHEC894_RS04450	COG1704	LemA family
RHEC894_RS04455	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
RHEC894_RS04465	COG0151	Belongs to the GarS family
RHEC894_RS04475	COG0751	glycine-tRNA ligase activity
RHEC894_RS04480	COG2183	response to ionizing radiation
RHEC894_RS04485	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
RHEC894_RS04500	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
RHEC894_RS04520	COG0009	L-threonylcarbamoyladenylate synthase
RHEC894_RS04535	COG4638	Rieske (2fe-2S)
RHEC894_RS04555	COG1960	acyl-CoA dehydrogenase activity
RHEC894_RS04570	COG1028	Short-chain dehydrogenase reductase Sdr
RHEC894_RS04575	COG1733	regulation of RNA biosynthetic process
RHEC894_RS04580	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
RHEC894_RS04595	COG0840	transmembrane signaling receptor activity
RHEC894_RS04600	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
RHEC894_RS04610	COG1741	Belongs to the pirin family
RHEC894_RS04620	COG1722	exodeoxyribonuclease VII activity
RHEC894_RS04625	COG0123	including yeast histone deacetylase and acetoin utilization protein
RHEC894_RS04650	COG1268	BioY protein
RHEC894_RS04655	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
RHEC894_RS04660	COG1122	ATPase activity
RHEC894_RS04665	COG3214	Protein conserved in bacteria
RHEC894_RS04670	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RHEC894_RS04670	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RHEC894_RS04675	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
RHEC894_RS04700	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
RHEC894_RS04705	COG0484	heat shock protein binding
RHEC894_RS04715	COG0259	pyridoxamine-phosphate oxidase activity
RHEC894_RS04725	COG1686	Belongs to the peptidase S11 family
RHEC894_RS04740	COG0312	modulator of DNA gyrase
RHEC894_RS04750	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
RHEC894_RS04755	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
RHEC894_RS04760	COG0109	protoheme IX farnesyltransferase activity
RHEC894_RS04765	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
RHEC894_RS04775	COG3385	transposase activity
RHEC894_RS04790	COG3346	SURF1 family
RHEC894_RS04795	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
RHEC894_RS04800	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
RHEC894_RS04805	COG0328	RNA-DNA hybrid ribonuclease activity
RHEC894_RS04830	COG1678	Uncharacterized ACR, COG1678
RHEC894_RS04840	COG0678	peroxiredoxin activity
RHEC894_RS04840	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
RHEC894_RS04850	COG1121	(ABC) transporter
RHEC894_RS04855	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RHEC894_RS04860	COG0803	Belongs to the bacterial solute-binding protein 9 family
RHEC894_RS04890	COG0612	Peptidase, M16
RHEC894_RS04910	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RHEC894_RS04915	COG2814	Major facilitator Superfamily
RHEC894_RS04925	COG2972	Histidine kinase
RHEC894_RS04925	COG0840	transmembrane signaling receptor activity
RHEC894_RS04965	COG2189	Belongs to the N(4) N(6)-methyltransferase family
RHEC894_RS04980	COG1194	a g-specific adenine glycosylase
RHEC894_RS05015	COG1196	nuclear chromosome segregation
RHEC894_RS05035	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
RHEC894_RS05035	COG0574	Belongs to the PEP-utilizing enzyme family
RHEC894_RS05130	COG4372	Transposase
RHEC894_RS05145	COG1028	Short-chain dehydrogenase reductase Sdr
RHEC894_RS05155	COG3385	transposase activity
RHEC894_RS05190	COG4948	Mandelate Racemase Muconate Lactonizing
RHEC894_RS05200	COG0583	DNA-binding transcription factor activity
RHEC894_RS05295	COG0590	tRNA wobble adenosine to inosine editing
RHEC894_RS05305	COG0642	Histidine kinase
RHEC894_RS05320	COG0640	Transcriptional regulator
RHEC894_RS05325	COG1028	Short-chain dehydrogenase reductase Sdr
RHEC894_RS05335	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
RHEC894_RS05455	COG0110	maltose O-acetyltransferase activity
RHEC894_RS05465	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
RHEC894_RS05480	COG0463	Glycosyl transferase, family 2
RHEC894_RS05550	COG1609	Transcriptional regulator
RHEC894_RS05575	COG0175	sulfate reduction
RHEC894_RS05580	COG0175	sulfate reduction
RHEC894_RS05585	COG1959	2 iron, 2 sulfur cluster binding
RHEC894_RS05610	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
RHEC894_RS05615	COG1012	belongs to the aldehyde dehydrogenase family
RHEC894_RS05620	COG1309	transcriptional regulator
RHEC894_RS05635	COG4943	cyclic-guanylate-specific phosphodiesterase activity
RHEC894_RS05640	COG0604	alcohol dehydrogenase
RHEC894_RS05640	COG3321	synthase
RHEC894_RS05645	COG2226	methyltransferase
RHEC894_RS05660	COG1349	DNA-binding transcription factor activity
RHEC894_RS05675	COG0625	glutathione transferase activity
RHEC894_RS05695	COG0583	DNA-binding transcription factor activity
RHEC894_RS05700	COG0435	Glutathione S-transferase
RHEC894_RS05715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RHEC894_RS05720	COG2944	sequence-specific DNA binding
RHEC894_RS05745	COG2203	Gaf domain
RHEC894_RS05745	COG5001	Diguanylate cyclase
RHEC894_RS05745	COG4251	negative regulation of phosphorylation
RHEC894_RS05745	COG3706	GGDEF domain
RHEC894_RS05750	COG0584	glycerophosphoryl diester phosphodiesterase
RHEC894_RS05760	COG0596	Alpha beta hydrolase
RHEC894_RS05765	COG2264	protein methyltransferase activity
RHEC894_RS05780	COG1793	dna ligase
RHEC894_RS05795	COG1376	ErfK ybiS ycfS ynhG family protein
RHEC894_RS05800	COG1376	ErfK ybiS ycfS ynhG family protein
RHEC894_RS05805	COG1278	Cold shock
RHEC894_RS05815	COG0828	Belongs to the bacterial ribosomal protein bS21 family
RHEC894_RS05825	COG1846	Transcriptional regulator
RHEC894_RS05830	COG1764	response to oxidative stress
RHEC894_RS05855	COG0488	(ABC) transporter
RHEC894_RS05865	COG0488	(ABC) transporter
RHEC894_RS05885	COG0433	COG0433 Predicted ATPase
RHEC894_RS05900	COG3609	addiction module antidote protein, CC2985 family
RHEC894_RS05905	COG1051	belongs to the nudix hydrolase family
RHEC894_RS05915	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
RHEC894_RS05920	COG4106	trans-aconitate 2-methyltransferase activity
RHEC894_RS05925	COG1253	flavin adenine dinucleotide binding
RHEC894_RS05940	COG1064	alcohol dehydrogenase
RHEC894_RS05945	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RHEC894_RS05965	COG0583	DNA-binding transcription factor activity
RHEC894_RS05990	COG0625	glutathione transferase activity
RHEC894_RS06000	COG2814	Major facilitator Superfamily
RHEC894_RS06010	COG0730	response to heat
RHEC894_RS06025	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
RHEC894_RS06035	COG3385	transposase activity
RHEC894_RS06045	COG1280	lysine exporter protein (LysE YggA)
RHEC894_RS06055	COG2910	NAD(P)H-binding
RHEC894_RS06065	COG0583	DNA-binding transcription factor activity
RHEC894_RS06075	COG2010	Cytochrome c
RHEC894_RS06105	COG4993	Dehydrogenase
RHEC894_RS06110	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
RHEC894_RS06115	COG0477	Major facilitator Superfamily
RHEC894_RS06160	COG2514	catechol 2,3-dioxygenase activity
RHEC894_RS06170	COG1272	protein, Hemolysin III
RHEC894_RS06175	COG1247	-acetyltransferase
RHEC894_RS06190	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
RHEC894_RS06200	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
RHEC894_RS06200	COG2111	Na H antiporter
RHEC894_RS06205	COG2111	Na H antiporter
RHEC894_RS06210	COG1006	Multisubunit Na H antiporter MnhC subunit
RHEC894_RS06220	COG0651	ATP synthesis coupled electron transport
RHEC894_RS06225	COG1863	multisubunit Na H antiporter MnhE subunit
RHEC894_RS06230	COG2212	antiporter activity
RHEC894_RS06235	COG1320	monovalent cation:proton antiporter activity
RHEC894_RS06240	COG4957	zinc ion binding
RHEC894_RS06245	COG2166	iron-sulfur cluster assembly
RHEC894_RS06255	COG2205	protein histidine kinase activity
RHEC894_RS06295	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
RHEC894_RS06300	COG2983	Belongs to the UPF0260 family
RHEC894_RS06325	COG4221	oxidoreductase activity
RHEC894_RS06330	COG3239	Fatty acid desaturase
RHEC894_RS06340	COG0583	DNA-binding transcription factor activity
RHEC894_RS06345	COG0662	Cupin 2, conserved barrel domain protein
RHEC894_RS06360	COG0583	DNA-binding transcription factor activity
RHEC894_RS06370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RHEC894_RS06385	COG0625	glutathione transferase activity
RHEC894_RS06400	COG1309	transcriptional regulator
RHEC894_RS06440	COG4235	cytochrome complex assembly
RHEC894_RS06445	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
RHEC894_RS06450	COG1138	Cytochrome C-type biogenesis protein
RHEC894_RS06455	COG3088	subunit of a heme lyase
RHEC894_RS06460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RHEC894_RS06465	COG0745	RESPONSE REGULATOR receiver
RHEC894_RS06470	COG2205	protein histidine kinase activity
RHEC894_RS06475	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
RHEC894_RS06480	COG2205	protein histidine kinase activity
RHEC894_RS06480	COG2202	Pas domain
RHEC894_RS06485	COG0308	aminopeptidase N
RHEC894_RS06490	COG0840	transmembrane signaling receptor activity
RHEC894_RS06490	COG3290	protein histidine kinase activity
RHEC894_RS06520	COG0443	Heat shock 70 kDa protein
RHEC894_RS06540	COG1028	Short-chain dehydrogenase reductase Sdr
RHEC894_RS06550	COG1376	ErfK ybiS ycfS ynhG family protein
RHEC894_RS06565	COG2239	Acts as a magnesium transporter
RHEC894_RS06570	COG2814	Major facilitator Superfamily
RHEC894_RS06580	COG0174	glutamine synthetase
RHEC894_RS06595	COG3609	addiction module antidote protein, CC2985 family
RHEC894_RS06600	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
RHEC894_RS06605	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
RHEC894_RS06610	COG0463	Glycosyl transferase, family 2
RHEC894_RS06615	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
RHEC894_RS06625	COG4941	Belongs to the sigma-70 factor family
RHEC894_RS06635	COG3795	YCII-related domain
RHEC894_RS06650	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
RHEC894_RS06670	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
RHEC894_RS06730	COG3718	enzyme involved in inositol metabolism
RHEC894_RS06735	COG1082	Xylose isomerase domain protein TIM barrel
RHEC894_RS06740	COG3962	Belongs to the TPP enzyme family
RHEC894_RS06745	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RHEC894_RS06755	COG0673	inositol 2-dehydrogenase activity
RHEC894_RS06785	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RHEC894_RS06790	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
RHEC894_RS06800	COG1758	RNA polymerase activity
RHEC894_RS06820	COG0736	holo-[acyl-carrier-protein] synthase activity
RHEC894_RS06825	COG0681	Belongs to the peptidase S26 family
RHEC894_RS06830	COG0571	ribonuclease III activity
RHEC894_RS06835	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
RHEC894_RS06840	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RHEC894_RS06850	COG1381	Involved in DNA repair and RecF pathway recombination
RHEC894_RS06855	COG0656	L-ascorbic acid biosynthetic process
RHEC894_RS06865	COG1418	mRNA catabolic process
RHEC894_RS06870	COG3300	MHYT domain
RHEC894_RS06870	COG5001	Diguanylate cyclase
RHEC894_RS06880	COG2032	superoxide dismutase activity
RHEC894_RS06885	COG0668	transmembrane transport
RHEC894_RS06895	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
RHEC894_RS06920	COG1051	belongs to the nudix hydrolase family
RHEC894_RS06925	COG1742	UPF0060 membrane protein
RHEC894_RS06940	COG0688	phosphatidylethanolamine metabolic process
RHEC894_RS06945	COG5265	(ABC) transporter
RHEC894_RS06965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RHEC894_RS06990	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RHEC894_RS07025	COG0215	cysteine-tRNA ligase activity
RHEC894_RS07035	COG4221	oxidoreductase activity
RHEC894_RS07040	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
RHEC894_RS07045	COG1286	toxin biosynthetic process
RHEC894_RS07065	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
RHEC894_RS07085	COG0305	Participates in initiation and elongation during chromosome replication
RHEC894_RS07090	COG0359	binds to the 23S rRNA
RHEC894_RS07100	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
RHEC894_RS07105	COG0360	Binds together with S18 to 16S ribosomal RNA
RHEC894_RS07110	COG0667	Aldo Keto reductase
RHEC894_RS07120	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
RHEC894_RS07130	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RHEC894_RS07135	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
RHEC894_RS07140	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
RHEC894_RS07145	COG1561	YicC-like family, N-terminal region
RHEC894_RS07150	COG0194	GDP metabolic process
RHEC894_RS07155	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
RHEC894_RS07160	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
RHEC894_RS07170	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
RHEC894_RS07185	COG0671	phosphoesterase, PA-phosphatase related
RHEC894_RS07190	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
RHEC894_RS07205	COG1505	serine-type exopeptidase activity
RHEC894_RS07210	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RHEC894_RS07215	COG2079	MmgE PrpD family protein
RHEC894_RS07225	COG0765	amino acid transport
RHEC894_RS07250	COG0488	(ABC) transporter
RHEC894_RS07255	COG3706	GGDEF domain
RHEC894_RS07270	COG0105	UTP biosynthetic process
RHEC894_RS07290	COG0314	molybdopterin synthase activity
RHEC894_RS07305	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
RHEC894_RS07310	COG0322	excinuclease ABC activity
RHEC894_RS07315	COG1028	Short-chain dehydrogenase reductase Sdr
RHEC894_RS07330	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
RHEC894_RS07335	COG0243	molybdopterin cofactor binding
RHEC894_RS07355	COG3454	Phosphonate metabolism
RHEC894_RS07360	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
RHEC894_RS07365	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
RHEC894_RS07370	COG0628	permease
RHEC894_RS07380	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
RHEC894_RS07395	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
RHEC894_RS07400	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
RHEC894_RS07405	COG2132	Multicopper oxidase
RHEC894_RS07415	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
RHEC894_RS07425	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
RHEC894_RS07435	COG3654	unkown
RHEC894_RS07440	COG2336	PFAM SpoVT AbrB
RHEC894_RS07450	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
RHEC894_RS07460	COG0113	porphobilinogen synthase activity
RHEC894_RS07480	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
RHEC894_RS07485	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
RHEC894_RS07490	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RHEC894_RS07490	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RHEC894_RS07500	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
RHEC894_RS07505	COG1091	dTDP-4-dehydrorhamnose reductase activity
RHEC894_RS07510	COG1088	dTDP-glucose 4,6-dehydratase activity
RHEC894_RS07515	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
RHEC894_RS07545	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
RHEC894_RS07550	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RHEC894_RS07555	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
RHEC894_RS07575	COG0416	fatty acid biosynthetic process
RHEC894_RS07580	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
RHEC894_RS07585	COG0776	regulation of translation
RHEC894_RS07615	COG1215	transferase activity, transferring glycosyl groups
RHEC894_RS07625	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
RHEC894_RS07635	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RHEC894_RS07645	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
RHEC894_RS07665	COG1940	carbohydrate kinase activity
RHEC894_RS07685	COG1175	transmembrane transport
RHEC894_RS07690	COG0395	ABC-type sugar transport system, permease component
RHEC894_RS07705	COG0297	glycogen (starch) synthase activity
RHEC894_RS07730	COG1612	heme a metabolic process
RHEC894_RS07740	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
RHEC894_RS07745	COG0010	Belongs to the arginase family
RHEC894_RS07750	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
RHEC894_RS07755	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
RHEC894_RS07770	COG1024	Enoyl-CoA hydratase
RHEC894_RS07785	COG1832	CoA-binding protein
RHEC894_RS07815	COG5001	Diguanylate cyclase
RHEC894_RS07820	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
RHEC894_RS07830	COG0581	inorganic phosphate transmembrane transporter activity
RHEC894_RS07835	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
RHEC894_RS07840	COG2124	cytochrome p450
RHEC894_RS07845	COG3706	GGDEF domain
RHEC894_RS07850	COG0740	serine-type endopeptidase activity
RHEC894_RS07855	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
RHEC894_RS07860	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
RHEC894_RS07865	COG0776	regulation of translation
RHEC894_RS07870	COG0697	spore germination
RHEC894_RS07880	COG0667	Aldo Keto reductase
RHEC894_RS07900	COG0386	Belongs to the glutathione peroxidase family
RHEC894_RS07925	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RHEC894_RS07930	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RHEC894_RS07935	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RHEC894_RS07940	COG0649	NAD binding
RHEC894_RS07950	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
RHEC894_RS07955	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
RHEC894_RS07960	COG3743	rRNA binding
RHEC894_RS07960	COG0261	This protein binds to 23S rRNA in the presence of protein L20
RHEC894_RS07970	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
RHEC894_RS07975	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RHEC894_RS07985	COG0713	ATP synthesis coupled electron transport
RHEC894_RS08000	COG1007	ATP synthesis coupled electron transport
RHEC894_RS08005	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
RHEC894_RS08005	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
RHEC894_RS08015	COG0346	lactoylglutathione lyase activity
RHEC894_RS08025	COG0442	prolyl-tRNA aminoacylation
RHEC894_RS08035	COG1136	(ABC) transporter
RHEC894_RS08055	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
RHEC894_RS08075	COG0784	Response regulator, receiver
RHEC894_RS08085	COG0267	Belongs to the bacterial ribosomal protein bL33 family
RHEC894_RS08090	COG0477	Major facilitator Superfamily
RHEC894_RS08100	COG0557	exoribonuclease II activity
RHEC894_RS08105	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
RHEC894_RS08110	COG0758	DNA mediated transformation
RHEC894_RS08115	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
RHEC894_RS08125	COG0540	Belongs to the ATCase OTCase family
RHEC894_RS08130	COG1960	acyl-CoA dehydrogenase activity
RHEC894_RS08135	COG3385	transposase activity
RHEC894_RS08145	COG1530	ribonuclease E activity
RHEC894_RS08150	COG0860	N-Acetylmuramoyl-L-alanine amidase
RHEC894_RS08155	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
RHEC894_RS08180	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
RHEC894_RS08205	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RHEC894_RS08220	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
RHEC894_RS08225	COG1086	Polysaccharide biosynthesis protein
RHEC894_RS08235	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
RHEC894_RS08245	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
RHEC894_RS08250	COG0081	regulation of translation
RHEC894_RS08255	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
RHEC894_RS08260	COG0222	ribosome binding
RHEC894_RS08265	COG0085	RNA polymerase activity
RHEC894_RS08270	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
RHEC894_RS08280	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
RHEC894_RS08285	COG0049	tRNA binding
RHEC894_RS08290	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
RHEC894_RS08295	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
RHEC894_RS08300	COG0051	transcription antitermination factor activity, RNA binding
RHEC894_RS08305	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
RHEC894_RS08310	COG0088	Forms part of the polypeptide exit tunnel
RHEC894_RS08315	COG0089	rRNA binding
RHEC894_RS08320	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
RHEC894_RS08325	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
RHEC894_RS08330	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
RHEC894_RS08335	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
RHEC894_RS08340	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
RHEC894_RS08345	COG0255	Belongs to the universal ribosomal protein uL29 family
RHEC894_RS08350	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
RHEC894_RS08355	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
RHEC894_RS08360	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
RHEC894_RS08365	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
RHEC894_RS08370	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
RHEC894_RS08375	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
RHEC894_RS08380	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
RHEC894_RS08385	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
RHEC894_RS08390	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
RHEC894_RS08395	COG1841	ribosomal large subunit assembly
RHEC894_RS08400	COG0200	Binds to the 23S rRNA
RHEC894_RS08405	COG0201	protein transport
RHEC894_RS08410	COG0563	adenylate kinase activity
RHEC894_RS08415	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
RHEC894_RS08420	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
RHEC894_RS08425	COG0202	RNA polymerase activity
RHEC894_RS08430	COG0203	ribosomal protein L17
RHEC894_RS08445	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
RHEC894_RS08450	COG0129	dihydroxy-acid dehydratase activity
RHEC894_RS08470	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
RHEC894_RS08500	COG5002	protein histidine kinase activity
RHEC894_RS08505	COG0681	Belongs to the peptidase S26 family
RHEC894_RS08510	COG1609	Transcriptional regulator
RHEC894_RS08520	COG1024	Enoyl-CoA hydratase
RHEC894_RS08525	COG1012	belongs to the aldehyde dehydrogenase family
RHEC894_RS08530	COG1653	transport
RHEC894_RS08535	COG1175	transmembrane transport
RHEC894_RS08540	COG0395	ABC-type sugar transport system, permease component
RHEC894_RS08545	COG3842	ATPase activity
RHEC894_RS08560	COG0673	inositol 2-dehydrogenase activity
RHEC894_RS08565	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
RHEC894_RS08590	COG2197	response regulator
RHEC894_RS08610	COG5001	Diguanylate cyclase
RHEC894_RS08650	COG1522	sequence-specific DNA binding
RHEC894_RS08655	COG1522	sequence-specific DNA binding
RHEC894_RS08665	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
RHEC894_RS08675	COG0625	glutathione transferase activity
RHEC894_RS08695	COG2423	ornithine cyclodeaminase activity
RHEC894_RS08700	COG4948	Mandelate Racemase Muconate Lactonizing
RHEC894_RS08705	COG0583	DNA-binding transcription factor activity
RHEC894_RS08720	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RHEC894_RS08730	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
RHEC894_RS08740	COG1058	Belongs to the CinA family
RHEC894_RS08740	COG1546	Belongs to the CinA family
RHEC894_RS08745	COG0655	NAD(P)H dehydrogenase (quinone) activity
RHEC894_RS08765	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
RHEC894_RS08780	COG3706	GGDEF domain
RHEC894_RS08795	COG1028	Short-chain dehydrogenase reductase Sdr
RHEC894_RS08805	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
RHEC894_RS08810	COG0583	DNA-binding transcription factor activity
RHEC894_RS08815	COG0737	Belongs to the 5'-nucleotidase family
RHEC894_RS08825	COG1028	Short-chain dehydrogenase reductase Sdr
RHEC894_RS08830	COG1028	Short-chain dehydrogenase reductase Sdr
RHEC894_RS08845	COG1522	sequence-specific DNA binding
RHEC894_RS08850	COG0686	Belongs to the AlaDH PNT family
RHEC894_RS08865	COG2897	thiosulfate sulfurtransferase activity
RHEC894_RS08870	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
RHEC894_RS08880	COG3806	Anti-sigma factor
RHEC894_RS08885	COG0300	oxidoreductase activity
RHEC894_RS08890	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
RHEC894_RS08895	COG0415	Belongs to the DNA photolyase family
RHEC894_RS08910	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RHEC894_RS08915	COG0243	molybdopterin cofactor binding
RHEC894_RS08925	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RHEC894_RS08935	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RHEC894_RS08940	COG3707	response regulator
RHEC894_RS08950	COG0450	alkyl hydroperoxide reductase
RHEC894_RS08995	COG0753	catalase activity
RHEC894_RS09050	COG1715	Restriction endonuclease
RHEC894_RS09080	COG0583	DNA-binding transcription factor activity
RHEC894_RS09100	COG0702	epimerase
RHEC894_RS09115	COG1733	regulation of RNA biosynthetic process
RHEC894_RS09125	COG1733	regulation of RNA biosynthetic process
RHEC894_RS09150	COG3846	protein secretion by the type IV secretion system
RHEC894_RS09165	COG3451	type IV secretory pathway VirB4
RHEC894_RS09180	COG4962	Type ii secretion system protein e
RHEC894_RS09200	COG0741	lytic transglycosylase activity
RHEC894_RS09210	COG4959	Type IV secretory pathway protease TraF
RHEC894_RS09225	COG1192	Involved in chromosome partitioning
RHEC894_RS09260	COG5489	Protein of unknown function (DUF736)
RHEC894_RS09295	COG1475	DNA binding
RHEC894_RS09345	COG2175	clavaminate synthase activity
RHEC894_RS09350	COG1196	nuclear chromosome segregation
RHEC894_RS09425	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
RHEC894_RS09435	COG0525	valine-tRNA ligase activity
RHEC894_RS09440	COG2067	long-chain fatty acid transport protein
RHEC894_RS09465	COG0232	Belongs to the dGTPase family. Type 2 subfamily
RHEC894_RS09470	COG0018	arginyl-trna synthetase
RHEC894_RS09480	COG1472	Belongs to the glycosyl hydrolase 3 family
RHEC894_RS09485	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
RHEC894_RS09495	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
RHEC894_RS09500	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
RHEC894_RS09505	COG0805	protein transport
RHEC894_RS09510	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
RHEC894_RS09515	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
RHEC894_RS09520	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
RHEC894_RS09530	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RHEC894_RS09540	COG1862	Preprotein translocase
RHEC894_RS09565	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
RHEC894_RS09595	COG0544	peptidyl-prolyl cis-trans isomerase activity
RHEC894_RS09605	COG1032	radical SAM domain protein
RHEC894_RS09620	COG2003	Belongs to the UPF0758 family
RHEC894_RS09625	COG1304	FMN binding
RHEC894_RS09635	COG2003	Belongs to the UPF0758 family
RHEC894_RS09640	COG0024	Methionine aminopeptidase
RHEC894_RS09655	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
RHEC894_RS09660	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
RHEC894_RS09665	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
RHEC894_RS09670	COG0154	amidase activity
RHEC894_RS09695	COG3811	Belongs to the UPF0386 family
RHEC894_RS09710	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
RHEC894_RS09730	COG4765	Protein conserved in bacteria
RHEC894_RS09745	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
RHEC894_RS09755	COG0511	ligase activity, forming carbon-carbon bonds
RHEC894_RS09760	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
RHEC894_RS09770	COG0436	Aminotransferase
RHEC894_RS09780	COG3243	poly(R)-hydroxyalkanoic acid synthase
RHEC894_RS09790	COG0436	Aminotransferase
RHEC894_RS09805	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
RHEC894_RS09840	COG1278	Cold shock
RHEC894_RS09905	COG1126	abc transporter atp-binding protein
RHEC894_RS09910	COG0765	amino acid transport
RHEC894_RS09915	COG4597	amino acid ABC transporter
RHEC894_RS09920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RHEC894_RS09925	COG0626	cystathionine gamma-synthase activity
RHEC894_RS09940	COG2267	carboxylic ester hydrolase activity
RHEC894_RS09960	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
RHEC894_RS09970	COG0537	adenosine 5'-monophosphoramidase activity
RHEC894_RS09995	COG3853	Toxic anion resistance protein (TelA)
RHEC894_RS10015	COG0052	Belongs to the universal ribosomal protein uS2 family
RHEC894_RS10020	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
RHEC894_RS10025	COG0528	UMP kinase activity
RHEC894_RS10030	COG0233	cytoplasmic translational termination
RHEC894_RS10035	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
RHEC894_RS10045	COG0750	zinc metalloprotease
RHEC894_RS10055	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
RHEC894_RS10060	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
RHEC894_RS10065	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
RHEC894_RS10075	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
RHEC894_RS10085	COG0658	competence protein
RHEC894_RS10085	COG2333	competence protein COMEC
RHEC894_RS10090	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
RHEC894_RS10100	COG2877	3-deoxy-8-phosphooctulonate synthase activity
RHEC894_RS10105	COG0148	phosphopyruvate hydratase activity
RHEC894_RS10115	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
RHEC894_RS10120	COG0508	dehydrogenase complex catalyzes the overall conversion of
RHEC894_RS10120	COG0022	dehydrogenase e1 component
RHEC894_RS10125	COG0508	dehydrogenase complex catalyzes the overall conversion of
RHEC894_RS10140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RHEC894_RS10155	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
RHEC894_RS10160	COG3385	transposase activity
RHEC894_RS10165	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
RHEC894_RS10165	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
RHEC894_RS10170	COG2867	negative regulation of translational initiation
RHEC894_RS10180	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
RHEC894_RS10180	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
RHEC894_RS10195	COG2204	response regulator
RHEC894_RS10200	COG1262	PFAM Formylglycine-generating sulfatase enzyme
RHEC894_RS10215	COG3119	arylsulfatase activity
RHEC894_RS10225	COG0667	Aldo Keto reductase
RHEC894_RS10230	COG3048	D-serine ammonia-lyase activity
RHEC894_RS10240	COG0765	amino acid transport
RHEC894_RS10245	COG4597	amino acid ABC transporter
RHEC894_RS10250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RHEC894_RS10255	COG0583	DNA-binding transcription factor activity
RHEC894_RS10260	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
RHEC894_RS10265	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
RHEC894_RS10275	COG5000	phosphorelay sensor kinase activity
RHEC894_RS10280	COG2204	response regulator
RHEC894_RS10285	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RHEC894_RS10290	COG1923	regulation of RNA biosynthetic process
RHEC894_RS10295	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
RHEC894_RS10300	COG3956	TIGRFAM MazG family protein
RHEC894_RS10330	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RHEC894_RS10335	COG0679	Auxin Efflux Carrier
RHEC894_RS10340	COG0785	Cytochrome C biogenesis protein
RHEC894_RS10360	COG3237	CsbD-like
RHEC894_RS10365	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RHEC894_RS10410	COG2249	NAD(P)H dehydrogenase (quinone) activity
RHEC894_RS10420	COG0402	S-adenosylhomocysteine deaminase activity
RHEC894_RS10430	COG1116	anion transmembrane transporter activity
RHEC894_RS10475	COG1653	transport
RHEC894_RS10480	COG1175	transmembrane transport
RHEC894_RS10485	COG0395	ABC-type sugar transport system, permease component
RHEC894_RS10490	COG3842	ATPase activity
RHEC894_RS10495	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RHEC894_RS10500	COG1312	Catalyzes the dehydration of D-mannonate
RHEC894_RS10505	COG2186	Transcriptional regulator
RHEC894_RS10510	COG0747	negative chemotaxis
RHEC894_RS10515	COG0601	transmembrane transport
RHEC894_RS10520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RHEC894_RS10525	COG0444	Belongs to the ABC transporter superfamily
RHEC894_RS10530	COG4608	Belongs to the ABC transporter superfamily
RHEC894_RS10555	COG0577	efflux transmembrane transporter activity
RHEC894_RS10555	COG1136	(ABC) transporter
RHEC894_RS10560	COG1136	(ABC) transporter
RHEC894_RS10560	COG0577	efflux transmembrane transporter activity
RHEC894_RS10580	COG1183	phosphatidylcholine synthase activity
RHEC894_RS10590	COG3845	ABC transporter
RHEC894_RS10600	COG1079	Belongs to the binding-protein-dependent transport system permease family
RHEC894_RS10610	COG1879	ABC-type sugar transport system periplasmic component
RHEC894_RS10615	COG1129	ABC transporter
RHEC894_RS10620	COG1172	Belongs to the binding-protein-dependent transport system permease family
RHEC894_RS10625	COG1172	Belongs to the binding-protein-dependent transport system permease family
RHEC894_RS10630	COG2186	Transcriptional regulator
RHEC894_RS10635	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
RHEC894_RS10640	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
RHEC894_RS10650	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
RHEC894_RS10660	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
RHEC894_RS10680	COG4166	transmembrane transport
RHEC894_RS10695	COG0174	glutamine synthetase
RHEC894_RS10700	COG0347	Belongs to the P(II) protein family
RHEC894_RS10705	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
RHEC894_RS10705	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
RHEC894_RS10720	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
RHEC894_RS10725	COG0629	single-stranded DNA binding
RHEC894_RS10745	COG2095	MarC family integral membrane protein
RHEC894_RS10750	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
RHEC894_RS10760	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
RHEC894_RS10775	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
RHEC894_RS10780	COG0343	queuine tRNA-ribosyltransferase activity
RHEC894_RS10795	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
RHEC894_RS10815	COG3842	ATPase activity
RHEC894_RS10825	COG1840	ABC-type Fe3 transport system, periplasmic component
RHEC894_RS10830	COG1840	ABC-type Fe3 transport system, periplasmic component
RHEC894_RS10875	COG1175	transmembrane transport
RHEC894_RS10890	COG1609	Transcriptional regulator
RHEC894_RS10895	COG0612	Peptidase, M16
RHEC894_RS10915	COG1956	GAF domain-containing protein
RHEC894_RS10920	COG3585	molybdate ion transport
RHEC894_RS10925	COG2801	Transposase and inactivated derivatives
RHEC894_RS10935	COG0668	transmembrane transport
RHEC894_RS10940	COG0596	Alpha beta hydrolase
RHEC894_RS10980	COG0861	Integral membrane protein TerC family
RHEC894_RS10985	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
RHEC894_RS10985	COG0321	lipoyl(octanoyl) transferase activity
RHEC894_RS10990	COG0084	hydrolase, TatD family'
RHEC894_RS10995	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RHEC894_RS11000	COG0730	response to heat
RHEC894_RS11010	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
RHEC894_RS11035	COG2824	Alkylphosphonate utilization operon protein PhnA
RHEC894_RS11070	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
RHEC894_RS11075	COG0134	indole-3-glycerol-phosphate synthase activity
RHEC894_RS11080	COG0315	cyclic pyranopterin monophosphate synthase activity
RHEC894_RS11085	COG0303	'Molybdopterin
RHEC894_RS11095	COG0513	Belongs to the DEAD box helicase family
RHEC894_RS11110	COG0372	Belongs to the citrate synthase family
RHEC894_RS11115	COG0372	Belongs to the citrate synthase family
RHEC894_RS11120	COG1262	PFAM Formylglycine-generating sulfatase enzyme
RHEC894_RS11130	COG3119	arylsulfatase activity
RHEC894_RS11140	COG0504	CTP synthase activity
RHEC894_RS11150	COG0149	triose-phosphate isomerase activity
RHEC894_RS11160	COG0187	DNA topoisomerase II activity
RHEC894_RS11170	COG0628	permease
RHEC894_RS11190	COG3077	Addiction module antitoxin, RelB DinJ family
RHEC894_RS11215	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
RHEC894_RS11230	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
RHEC894_RS11235	COG0822	iron-sulfur transferase activity
RHEC894_RS11240	COG0302	gtp cyclohydrolase
RHEC894_RS11245	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
RHEC894_RS11250	COG1752	Esterase of the alpha-beta hydrolase superfamily
RHEC894_RS11255	COG2239	Acts as a magnesium transporter
RHEC894_RS11275	COG2267	carboxylic ester hydrolase activity
RHEC894_RS11295	COG1686	Belongs to the peptidase S11 family
RHEC894_RS11310	COG1760	l-serine dehydratase
RHEC894_RS11320	COG1959	2 iron, 2 sulfur cluster binding
RHEC894_RS11340	COG2239	Acts as a magnesium transporter
RHEC894_RS11345	COG0242	peptide deformylase activity
RHEC894_RS11365	COG0321	lipoyl(octanoyl) transferase activity
RHEC894_RS11385	COG4770	biotin carboxylase activity
RHEC894_RS11390	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
RHEC894_RS11395	COG2153	protein acetylation
RHEC894_RS11400	COG1671	Belongs to the UPF0178 family
RHEC894_RS11410	COG2259	Doxx family
RHEC894_RS11415	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
RHEC894_RS11430	COG0546	phosphoglycolate phosphatase activity
RHEC894_RS11440	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
RHEC894_RS11460	COG0404	The glycine cleavage system catalyzes the degradation of glycine
RHEC894_RS11465	COG0509	glycine decarboxylation via glycine cleavage system
RHEC894_RS11470	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
RHEC894_RS11470	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
RHEC894_RS11485	COG0316	Belongs to the HesB IscA family
RHEC894_RS11490	COG2151	metal-sulfur cluster biosynthetic enzyme
RHEC894_RS11495	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
RHEC894_RS11500	COG0719	Fe-S assembly protein
RHEC894_RS11505	COG0396	ATPase activity
RHEC894_RS11515	COG0719	Fe-S assembly protein
RHEC894_RS11520	COG1104	cysteine desulfurase activity
RHEC894_RS11525	COG2945	thiolester hydrolase activity
RHEC894_RS11535	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
RHEC894_RS11540	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
RHEC894_RS11560	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
RHEC894_RS11565	COG2833	Protein of unknown function (DUF455)
RHEC894_RS11570	COG0739	heme binding
RHEC894_RS11570	COG1196	nuclear chromosome segregation
RHEC894_RS11570	COG0741	lytic transglycosylase activity
RHEC894_RS11575	COG0513	Belongs to the DEAD box helicase family
RHEC894_RS11590	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RHEC894_RS11615	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
RHEC894_RS11640	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
RHEC894_RS11645	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
RHEC894_RS11650	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
RHEC894_RS11655	COG0047	phosphoribosylformylglycinamidine synthase activity
RHEC894_RS11670	COG2186	Transcriptional regulator
RHEC894_RS11680	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
RHEC894_RS11705	COG2814	Major facilitator Superfamily
RHEC894_RS11710	COG2814	Major facilitator Superfamily
RHEC894_RS11720	COG0483	inositol monophosphate 1-phosphatase activity
RHEC894_RS11725	COG0483	inositol monophosphate 1-phosphatase activity
RHEC894_RS11730	COG0037	tRNA processing
RHEC894_RS11735	COG2066	Belongs to the glutaminase family
RHEC894_RS11740	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
RHEC894_RS11750	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
RHEC894_RS11755	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
RHEC894_RS11770	COG0538	isocitrate dehydrogenase activity
RHEC894_RS11790	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
RHEC894_RS11795	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
RHEC894_RS11805	COG2313	pseudouridylate synthase activity
RHEC894_RS11835	COG3106	COG3106 Predicted ATPase
RHEC894_RS11840	COG3768	UPF0283 membrane protein
RHEC894_RS11850	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
RHEC894_RS11860	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
RHEC894_RS11870	COG0633	Ferredoxin
RHEC894_RS11895	COG1686	Belongs to the peptidase S11 family
RHEC894_RS11915	COG1127	ABC transporter
RHEC894_RS11925	COG4948	Mandelate Racemase Muconate Lactonizing
RHEC894_RS11930	COG2814	Major facilitator Superfamily
RHEC894_RS11950	COG0740	serine-type endopeptidase activity
RHEC894_RS11960	COG0640	Transcriptional regulator
RHEC894_RS11975	COG1309	transcriptional regulator
RHEC894_RS11985	COG0281	malic enzyme
RHEC894_RS11985	COG0280	phosphate acetyltransferase
RHEC894_RS12000	COG0778	Nitroreductase
RHEC894_RS12005	COG0477	Major facilitator Superfamily
RHEC894_RS12010	COG0840	transmembrane signaling receptor activity
RHEC894_RS12020	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
RHEC894_RS12045	COG0823	Involved in the tonB-independent uptake of proteins
RHEC894_RS12065	COG1132	(ABC) transporter
RHEC894_RS12070	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
RHEC894_RS12105	COG1254	Belongs to the acylphosphatase family
RHEC894_RS12115	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
RHEC894_RS12120	COG0546	phosphoglycolate phosphatase activity
RHEC894_RS12130	COG2989	Protein conserved in bacteria
RHEC894_RS12140	COG0114	fumarate hydratase activity
RHEC894_RS12155	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
RHEC894_RS12155	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
RHEC894_RS12160	COG3706	GGDEF domain
RHEC894_RS12180	COG1846	Transcriptional regulator
RHEC894_RS12200	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
RHEC894_RS12205	COG2226	methyltransferase
RHEC894_RS12215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RHEC894_RS12220	COG1120	ATPase activity
RHEC894_RS12225	COG2390	Transcriptional regulator
RHEC894_RS12230	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
RHEC894_RS12235	COG3958	Transketolase
RHEC894_RS12240	COG3959	Transketolase, thiamine diphosphate binding domain
RHEC894_RS12245	COG1172	Belongs to the binding-protein-dependent transport system permease family
RHEC894_RS12250	COG1879	ABC-type sugar transport system periplasmic component
RHEC894_RS12255	COG1129	ABC transporter
RHEC894_RS12260	COG1028	Short-chain dehydrogenase reductase Sdr
RHEC894_RS12265	COG1028	Short-chain dehydrogenase reductase Sdr
RHEC894_RS12280	COG0746	molybdenum cofactor guanylyltransferase activity
RHEC894_RS12285	COG1763	Mo-molybdopterin cofactor biosynthetic process
RHEC894_RS12295	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
RHEC894_RS12310	COG0667	Aldo Keto reductase
RHEC894_RS12320	COG2205	protein histidine kinase activity
RHEC894_RS12330	COG0596	Alpha beta hydrolase
RHEC894_RS12345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RHEC894_RS12360	COG5425	PFAM Usg family protein
RHEC894_RS12415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RHEC894_RS12425	COG2084	Dehydrogenase
RHEC894_RS12435	COG0583	DNA-binding transcription factor activity
RHEC894_RS12450	COG1522	sequence-specific DNA binding
RHEC894_RS12455	COG1573	uracil-dna glycosylase
RHEC894_RS12475	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
RHEC894_RS12480	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
RHEC894_RS12510	COG1028	Short-chain dehydrogenase reductase Sdr
RHEC894_RS12515	COG0842	Transport permease protein
RHEC894_RS12520	COG1131	(ABC) transporter
RHEC894_RS12525	COG3507	Belongs to the glycosyl hydrolase 43 family
RHEC894_RS12530	COG0667	Aldo Keto reductase
RHEC894_RS12535	COG0673	inositol 2-dehydrogenase activity
RHEC894_RS12555	COG0395	ABC-type sugar transport system, permease component
RHEC894_RS12560	COG1175	transmembrane transport
RHEC894_RS12610	COG3153	acetyltransferase
RHEC894_RS12620	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
RHEC894_RS12655	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
RHEC894_RS12665	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
RHEC894_RS12670	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RHEC894_RS12755	COG1028	Short-chain dehydrogenase reductase Sdr
RHEC894_RS12760	COG1492	cobalamin metabolic process
RHEC894_RS12780	COG0583	DNA-binding transcription factor activity
RHEC894_RS12790	COG1279	arginine transmembrane transporter activity
RHEC894_RS12795	COG0583	DNA-binding transcription factor activity
RHEC894_RS12805	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
RHEC894_RS12810	COG1285	pathogenesis
RHEC894_RS12855	COG0745	RESPONSE REGULATOR receiver
RHEC894_RS12870	COG1393	Belongs to the ArsC family
RHEC894_RS12880	COG3264	Mechanosensitive ion channel
RHEC894_RS12880	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
RHEC894_RS12890	COG0745	RESPONSE REGULATOR receiver
RHEC894_RS12895	COG2814	Major facilitator Superfamily
RHEC894_RS12930	COG1846	Transcriptional regulator
RHEC894_RS12935	COG0494	nUDIX hydrolase
RHEC894_RS12945	COG1764	response to oxidative stress
RHEC894_RS12970	COG1607	acyl-coa hydrolase
RHEC894_RS13000	COG2814	Major facilitator Superfamily
RHEC894_RS13010	COG0702	epimerase
RHEC894_RS13025	COG0784	Response regulator, receiver
RHEC894_RS13065	COG0556	nucleotide-excision repair
RHEC894_RS13090	COG4372	Transposase
RHEC894_RS13110	COG0456	acetyltransferase
RHEC894_RS13125	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
RHEC894_RS13130	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RHEC894_RS13155	COG0431	NADPH-dependent FMN reductase
RHEC894_RS13160	COG1129	ABC transporter
RHEC894_RS13160	COG0842	Transport permease protein
RHEC894_RS13215	COG0702	epimerase
RHEC894_RS13225	COG0137	argininosuccinate synthase activity
RHEC894_RS13230	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
RHEC894_RS13240	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
RHEC894_RS13265	COG0406	alpha-ribazole phosphatase activity
RHEC894_RS13280	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
RHEC894_RS13315	COG3158	transport of potassium into the cell
RHEC894_RS13355	COG1136	(ABC) transporter
RHEC894_RS13365	COG1917	Cupin 2, conserved barrel domain protein
RHEC894_RS13365	COG2207	Transcriptional regulator
RHEC894_RS13380	COG1845	cytochrome c oxidase, subunit III
RHEC894_RS13385	COG1845	cytochrome c oxidase, subunit III
RHEC894_RS13390	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
RHEC894_RS13395	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
RHEC894_RS13420	COG1120	ATPase activity
RHEC894_RS13425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RHEC894_RS13435	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RHEC894_RS13435	COG3453	Protein conserved in bacteria
RHEC894_RS13460	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
RHEC894_RS13480	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RHEC894_RS13505	COG3300	MHYT domain
RHEC894_RS13505	COG5001	Diguanylate cyclase
RHEC894_RS13520	COG2208	phosphoserine phosphatase activity
RHEC894_RS13550	COG3300	MHYT domain
RHEC894_RS13550	COG5001	Diguanylate cyclase
RHEC894_RS13620	COG0395	ABC-type sugar transport system, permease component
RHEC894_RS13635	COG1846	Transcriptional regulator
RHEC894_RS13635	COG1940	carbohydrate kinase activity
RHEC894_RS13655	COG0697	spore germination
RHEC894_RS13660	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RHEC894_RS13665	COG2204	response regulator
RHEC894_RS13670	COG5002	protein histidine kinase activity
RHEC894_RS13695	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
RHEC894_RS13700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RHEC894_RS13730	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
RHEC894_RS13800	COG2329	Antibiotic biosynthesis monooxygenase
RHEC894_RS13805	COG0519	Catalyzes the synthesis of GMP from XMP
RHEC894_RS13860	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RHEC894_RS13865	COG1121	(ABC) transporter
RHEC894_RS13875	COG0523	cobalamin synthesis protein
RHEC894_RS13890	COG1253	flavin adenine dinucleotide binding
RHEC894_RS13930	COG0384	phenazine biosynthesis protein PhzF
RHEC894_RS13945	COG3842	ATPase activity
RHEC894_RS13950	COG1176	ABC-type spermidine putrescine transport system, permease component I
RHEC894_RS13970	COG0667	Aldo Keto reductase
RHEC894_RS13975	COG5634	Uncharacterized conserved protein (DUF2278)
RHEC894_RS13980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RHEC894_RS13985	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RHEC894_RS14015	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
RHEC894_RS14040	COG0463	Glycosyl transferase, family 2
RHEC894_RS14045	COG2207	Transcriptional regulator
RHEC894_RS14050	COG1064	alcohol dehydrogenase
RHEC894_RS14060	COG0446	pyridine nucleotide-disulphide oxidoreductase
RHEC894_RS14075	COG1522	sequence-specific DNA binding
RHEC894_RS14080	COG1794	racemase activity, acting on amino acids and derivatives
RHEC894_RS14085	COG1846	Transcriptional regulator
RHEC894_RS14085	COG0456	acetyltransferase
RHEC894_RS14090	COG1309	transcriptional regulator
RHEC894_RS14095	COG2814	Major facilitator Superfamily
RHEC894_RS14105	COG1733	regulation of RNA biosynthetic process
RHEC894_RS14115	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
RHEC894_RS14125	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
RHEC894_RS14150	COG0668	transmembrane transport
RHEC894_RS14210	COG0656	L-ascorbic acid biosynthetic process
RHEC894_RS14220	COG0440	acetolactate synthase activity
RHEC894_RS14225	COG0028	Belongs to the TPP enzyme family
RHEC894_RS14245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RHEC894_RS14255	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
RHEC894_RS14260	COG0560	Phosphoserine phosphatase
RHEC894_RS14275	COG0330	HflC and HflK could
RHEC894_RS14280	COG0330	HflC and HflK could
RHEC894_RS14290	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
RHEC894_RS14320	COG0277	FAD linked oxidase domain protein
RHEC894_RS14325	COG0667	Aldo Keto reductase
RHEC894_RS14335	COG3180	Ammonia monooxygenase
RHEC894_RS14350	COG2885	chlorophyll binding
RHEC894_RS14355	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
RHEC894_RS14360	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RHEC894_RS14375	COG2719	SpoVR family
RHEC894_RS14380	COG2718	Belongs to the UPF0229 family
RHEC894_RS14385	COG2766	serine protein kinase
RHEC894_RS14410	COG1335	isochorismatase
RHEC894_RS14440	COG0006	proline dipeptidase activity
RHEC894_RS14445	COG2264	protein methyltransferase activity
RHEC894_RS14450	COG1999	signal sequence binding
RHEC894_RS14455	COG0835	chemotaxis
RHEC894_RS14475	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
RHEC894_RS14485	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
RHEC894_RS14495	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
RHEC894_RS14500	COG0849	cell division
RHEC894_RS14505	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
RHEC894_RS14510	COG1181	Belongs to the D-alanine--D-alanine ligase family
RHEC894_RS14520	COG0812	UDP-N-acetylmuramate dehydrogenase activity
RHEC894_RS14525	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
RHEC894_RS14530	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
RHEC894_RS14540	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
RHEC894_RS14545	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
RHEC894_RS14555	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
RHEC894_RS14570	COG0275	rRNA processing
RHEC894_RS14575	COG2001	Belongs to the MraZ family
RHEC894_RS14600	COG3023	N-Acetylmuramoyl-L-alanine amidase
RHEC894_RS14605	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
RHEC894_RS14615	COG1280	lysine exporter protein (LysE YggA)
RHEC894_RS14640	COG3757	hydrolase, family 25
RHEC894_RS14655	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
RHEC894_RS14680	COG0697	spore germination
RHEC894_RS14685	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RHEC894_RS14690	COG0028	Belongs to the TPP enzyme family
RHEC894_RS14695	COG0251	oxidation-reduction process
RHEC894_RS14710	COG1376	ErfK ybiS ycfS ynhG family protein
RHEC894_RS14715	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RHEC894_RS14720	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RHEC894_RS14730	COG1192	Involved in chromosome partitioning
RHEC894_RS14745	COG0174	glutamine synthetase
RHEC894_RS14775	COG2011	ABC-type metal ion transport system permease component
RHEC894_RS14780	COG3842	ATPase activity
RHEC894_RS14790	COG0673	inositol 2-dehydrogenase activity
RHEC894_RS14795	COG0395	ABC-type sugar transport system, permease component
RHEC894_RS14800	COG1175	transmembrane transport
RHEC894_RS14810	COG2971	BadF BadG BcrA BcrD
RHEC894_RS14815	COG2188	Transcriptional regulator
RHEC894_RS14845	COG4702	Belongs to the UPF0303 family
RHEC894_RS14850	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RHEC894_RS14860	COG0395	ABC-type sugar transport system, permease component
RHEC894_RS14865	COG1176	ABC-type spermidine putrescine transport system, permease component I
RHEC894_RS14875	COG3842	ATPase activity
RHEC894_RS14905	COG2827	Endonuclease containing a URI domain
RHEC894_RS14970	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
RHEC894_RS15025	COG2968	Membrane
RHEC894_RS15040	COG0432	Pfam Uncharacterised protein family UPF0047
RHEC894_RS15045	COG3338	carbonate dehydratase activity
RHEC894_RS15050	COG5507	3-demethylubiquinone-9 3-methyltransferase
RHEC894_RS15100	COG2207	Transcriptional regulator
RHEC894_RS15100	COG1917	Cupin 2, conserved barrel domain protein
RHEC894_RS15125	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
RHEC894_RS15135	COG1063	alcohol dehydrogenase
RHEC894_RS15145	COG0514	ATP-dependent DNA helicase (RecQ)
RHEC894_RS15150	COG0358	DNA primase activity
RHEC894_RS15170	COG0505	Belongs to the CarA family
RHEC894_RS15180	COG0534	Mate efflux family protein
RHEC894_RS15190	COG0667	Aldo Keto reductase
RHEC894_RS15195	COG2321	neutral zinc metallopeptidase
RHEC894_RS15200	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
RHEC894_RS15215	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
RHEC894_RS15225	COG3385	transposase activity
RHEC894_RS15230	COG1301	dicarboxylic acid transport
RHEC894_RS15235	COG4191	Histidine kinase
RHEC894_RS15240	COG2204	response regulator
RHEC894_RS15245	COG1522	sequence-specific DNA binding
RHEC894_RS15250	COG0492	ferredoxin-NADP+ reductase activity
RHEC894_RS15255	COG0583	DNA-binding transcription factor activity
RHEC894_RS15265	COG2814	Major facilitator Superfamily
RHEC894_RS15270	COG1902	pentaerythritol trinitrate reductase activity
RHEC894_RS15290	COG1175	transmembrane transport
RHEC894_RS15295	COG0395	ABC-type sugar transport system, permease component
RHEC894_RS15305	COG3842	ATPase activity
RHEC894_RS15310	COG3842	ATPase activity
RHEC894_RS15325	COG0583	DNA-binding transcription factor activity
RHEC894_RS15335	COG0387	Pfam Sodium calcium exchanger
RHEC894_RS15350	COG1442	glycosyl transferase family 8
RHEC894_RS15380	COG2133	pyrroloquinoline quinone binding
RHEC894_RS15395	COG1278	Cold shock
RHEC894_RS15410	COG0745	RESPONSE REGULATOR receiver
RHEC894_RS15415	COG1846	Transcriptional regulator
RHEC894_RS15435	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RHEC894_RS15440	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RHEC894_RS15460	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
RHEC894_RS15485	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
RHEC894_RS15495	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
RHEC894_RS15500	COG3300	MHYT domain
RHEC894_RS15500	COG5001	Diguanylate cyclase
RHEC894_RS15510	COG0193	aminoacyl-tRNA hydrolase activity
RHEC894_RS15520	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
RHEC894_RS15540	COG2030	dehydratase
RHEC894_RS15545	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
RHEC894_RS15550	COG2857	Cytochrome c1
RHEC894_RS15550	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
RHEC894_RS15570	COG1132	(ABC) transporter
RHEC894_RS15590	COG1132	(ABC) transporter
RHEC894_RS15595	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
RHEC894_RS15600	COG1283	sodium-dependent phosphate transmembrane transporter activity
RHEC894_RS15610	COG0408	coproporphyrinogen oxidase activity
RHEC894_RS15625	COG0617	tRNA 3'-terminal CCA addition
RHEC894_RS15640	COG0714	Associated with various cellular activities
RHEC894_RS15660	COG0454	-acetyltransferase
RHEC894_RS15670	COG0435	Glutathione S-transferase
RHEC894_RS15700	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RHEC894_RS15705	COG3135	benzoate transporter
RHEC894_RS15710	COG0740	serine-type endopeptidase activity
RHEC894_RS15715	COG3416	Protein conserved in bacteria
RHEC894_RS15720	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
RHEC894_RS15725	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
RHEC894_RS15745	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
RHEC894_RS15745	COG0512	Glutamine amidotransferase of anthranilate synthase
RHEC894_RS15765	COG2759	Belongs to the formate--tetrahydrofolate ligase family
RHEC894_RS15770	COG2862	Uncharacterized protein family, UPF0114
RHEC894_RS15780	COG2197	response regulator
RHEC894_RS15800	COG1435	thymidine kinase activity
RHEC894_RS15815	COG4175	Glycine betaine
RHEC894_RS15830	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RHEC894_RS15845	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
RHEC894_RS15860	COG0366	Alpha amylase catalytic
RHEC894_RS15870	COG0601	transmembrane transport
RHEC894_RS15875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RHEC894_RS15885	COG4608	Belongs to the ABC transporter superfamily
RHEC894_RS15895	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RHEC894_RS15920	COG1846	Transcriptional regulator
RHEC894_RS15925	COG1160	GTP binding
RHEC894_RS15945	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
RHEC894_RS15955	COG0024	Methionine aminopeptidase
RHEC894_RS15975	COG4941	Belongs to the sigma-70 factor family
RHEC894_RS15980	COG3795	YCII-related domain
RHEC894_RS15985	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
RHEC894_RS15990	COG1028	Short-chain dehydrogenase reductase Sdr
RHEC894_RS16000	COG1529	Aldehyde oxidase and xanthine dehydrogenase
RHEC894_RS16025	COG0583	DNA-binding transcription factor activity
RHEC894_RS16040	COG0402	S-adenosylhomocysteine deaminase activity
RHEC894_RS16045	COG3609	addiction module antidote protein, CC2985 family
RHEC894_RS16065	COG2453	phosphatase
RHEC894_RS16065	COG0671	phosphoesterase, PA-phosphatase related
RHEC894_RS16070	COG2267	carboxylic ester hydrolase activity
RHEC894_RS16075	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
RHEC894_RS16090	COG2268	Band 7 protein
RHEC894_RS16100	COG2351	hydroxyisourate hydrolase activity
RHEC894_RS16105	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
RHEC894_RS16115	COG3195	allantoin biosynthetic process
RHEC894_RS16115	COG3648	Uricase
RHEC894_RS16130	COG2022	thiamine diphosphate biosynthetic process
RHEC894_RS16130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RHEC894_RS16135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RHEC894_RS16135	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
RHEC894_RS16140	COG3609	addiction module antidote protein, CC2985 family
RHEC894_RS16150	COG5002	protein histidine kinase activity
RHEC894_RS16150	COG2205	protein histidine kinase activity
RHEC894_RS16150	COG0784	Response regulator, receiver
RHEC894_RS16165	COG4335	DNA alkylation repair
RHEC894_RS16170	COG0513	Belongs to the DEAD box helicase family
RHEC894_RS16190	COG2308	Evidence 4 Homologs of previously reported genes of
RHEC894_RS16205	COG0129	dihydroxy-acid dehydratase activity
RHEC894_RS16210	COG1012	belongs to the aldehyde dehydrogenase family
RHEC894_RS16220	COG4214	carbohydrate transport
RHEC894_RS16250	COG0673	inositol 2-dehydrogenase activity
RHEC894_RS16260	COG4213	ABC transporter substrate-binding protein
RHEC894_RS16265	COG4214	carbohydrate transport
RHEC894_RS16270	COG1129	ABC transporter
RHEC894_RS16355	COG4372	Transposase
RHEC894_RS16365	COG0495	leucyl-tRNA aminoacylation
RHEC894_RS16375	COG2755	lipolytic protein G-D-S-L family
RHEC894_RS16375	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
RHEC894_RS16400	COG3108	Peptidase M15
RHEC894_RS16425	COG1396	sequence-specific DNA binding
RHEC894_RS16430	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
RHEC894_RS16450	COG0438	transferase activity, transferring glycosyl groups
RHEC894_RS16480	COG0463	Glycosyl transferase, family 2
RHEC894_RS16485	COG1215	transferase activity, transferring glycosyl groups
RHEC894_RS16510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RHEC894_RS16515	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
RHEC894_RS16535	COG3206	protein involved in exopolysaccharide biosynthesis
RHEC894_RS16535	COG0489	protein tyrosine kinase activity
RHEC894_RS16560	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
RHEC894_RS16565	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
RHEC894_RS16580	COG0400	carboxylic ester hydrolase activity
RHEC894_RS16585	COG0346	lactoylglutathione lyase activity
RHEC894_RS16590	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
RHEC894_RS16595	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
RHEC894_RS16595	COG0662	Cupin 2, conserved barrel domain protein
RHEC894_RS16610	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RHEC894_RS16620	COG1309	transcriptional regulator
RHEC894_RS16625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RHEC894_RS16630	COG1131	(ABC) transporter
RHEC894_RS16635	COG0842	Transport permease protein
RHEC894_RS16640	COG0842	Transport permease protein
RHEC894_RS16655	COG0673	inositol 2-dehydrogenase activity
RHEC894_RS16675	COG2346	COG2346, Truncated hemoglobins
RHEC894_RS16720	COG4558	Periplasmic binding protein
RHEC894_RS16725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RHEC894_RS16730	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
RHEC894_RS16755	COG0784	Response regulator, receiver
RHEC894_RS16775	COG0653	protein targeting
RHEC894_RS16780	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
RHEC894_RS16810	COG1309	transcriptional regulator
RHEC894_RS16845	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RHEC894_RS16850	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RHEC894_RS16855	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RHEC894_RS16870	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
RHEC894_RS16875	COG0830	nickel cation binding
RHEC894_RS16880	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
RHEC894_RS16885	COG3706	GGDEF domain
RHEC894_RS16895	COG0804	urea catabolic process
RHEC894_RS16900	COG1442	glycosyl transferase family 8
RHEC894_RS16905	COG3755	Protein conserved in bacteria
RHEC894_RS16910	COG0832	Belongs to the urease beta subunit family
RHEC894_RS16915	COG3813	Protein conserved in bacteria
RHEC894_RS16920	COG0831	urea catabolic process
RHEC894_RS16925	COG0829	nickel cation binding
RHEC894_RS16965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RHEC894_RS16965	COG2205	protein histidine kinase activity
RHEC894_RS16975	COG0683	leucine binding
RHEC894_RS17000	COG0559	Belongs to the binding-protein-dependent transport system permease family
RHEC894_RS17075	COG0564	pseudouridine synthase activity
RHEC894_RS17080	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
RHEC894_RS17090	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
RHEC894_RS17110	COG0129	dihydroxy-acid dehydratase activity
RHEC894_RS17115	COG2084	Dehydrogenase
RHEC894_RS17130	COG0657	acetylesterase activity
RHEC894_RS17145	COG2010	Cytochrome c
RHEC894_RS17195	COG1028	Short-chain dehydrogenase reductase Sdr
RHEC894_RS17210	COG2094	Belongs to the DNA glycosylase MPG family
RHEC894_RS17220	COG1566	PFAM secretion protein HlyD family protein
RHEC894_RS17235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RHEC894_RS17245	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
RHEC894_RS17255	COG1959	2 iron, 2 sulfur cluster binding
RHEC894_RS17260	COG1028	Short-chain dehydrogenase reductase Sdr
RHEC894_RS17265	COG3622	Belongs to the hyi family
RHEC894_RS17280	COG3842	ATPase activity
RHEC894_RS17285	COG0395	ABC-type sugar transport system, permease component
RHEC894_RS17290	COG1175	transmembrane transport
RHEC894_RS17295	COG1653	transport
RHEC894_RS17300	COG1846	Transcriptional regulator
RHEC894_RS17300	COG1940	carbohydrate kinase activity
RHEC894_RS17305	COG1653	transport
RHEC894_RS17325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RHEC894_RS17340	COG2244	polysaccharide biosynthetic process
RHEC894_RS17345	COG0438	transferase activity, transferring glycosyl groups
RHEC894_RS17365	COG0489	protein tyrosine kinase activity
RHEC894_RS17375	COG1596	polysaccharide export
RHEC894_RS17425	COG4993	Dehydrogenase
RHEC894_RS17435	COG2186	Transcriptional regulator
RHEC894_RS17445	COG0702	epimerase
RHEC894_RS17450	COG1129	ABC transporter
RHEC894_RS17455	COG1172	Belongs to the binding-protein-dependent transport system permease family
RHEC894_RS17460	COG2354	Protein conserved in bacteria
RHEC894_RS17465	COG2086	electron transfer activity
RHEC894_RS17470	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RHEC894_RS17480	COG1250	3-hydroxyacyl-CoA dehydrogenase
RHEC894_RS17485	COG1960	acyl-CoA dehydrogenase activity
RHEC894_RS17490	COG0583	DNA-binding transcription factor activity
RHEC894_RS17525	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
RHEC894_RS17540	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
RHEC894_RS17550	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RHEC894_RS17555	COG0410	ABC transporter
RHEC894_RS17565	COG1172	Belongs to the binding-protein-dependent transport system permease family
RHEC894_RS17590	COG0179	Fumarylacetoacetate (FAA) hydrolase
RHEC894_RS17645	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
RHEC894_RS17650	COG3273	potassium ion transport
RHEC894_RS17650	COG0471	metal ion transport
RHEC894_RS17655	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
RHEC894_RS17670	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RHEC894_RS17690	COG1176	ABC-type spermidine putrescine transport system, permease component I
RHEC894_RS17695	COG1177	transmembrane transport
RHEC894_RS17710	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
RHEC894_RS17715	COG1473	amidohydrolase
RHEC894_RS17750	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
RHEC894_RS17775	COG5001	Diguanylate cyclase
RHEC894_RS17775	COG3300	MHYT domain
RHEC894_RS17780	COG0306	phosphate transporter
RHEC894_RS17785	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
RHEC894_RS17810	COG0482	sulfurtransferase activity
RHEC894_RS17815	COG0697	spore germination
RHEC894_RS17825	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RHEC894_RS17845	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
RHEC894_RS17850	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RHEC894_RS17855	COG0037	tRNA processing
RHEC894_RS17865	COG2885	chlorophyll binding
RHEC894_RS17870	COG0823	Involved in the tonB-independent uptake of proteins
RHEC894_RS17885	COG0848	biopolymer transport protein
RHEC894_RS17895	COG0824	Thioesterase
RHEC894_RS17920	COG1692	metallophosphoesterase
RHEC894_RS17935	COG0217	transcriptional regulatory protein
RHEC894_RS17940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RHEC894_RS17945	COG0840	transmembrane signaling receptor activity
RHEC894_RS17950	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
RHEC894_RS17965	COG0632	four-way junction helicase activity
RHEC894_RS17970	COG2255	four-way junction helicase activity
RHEC894_RS17975	COG1408	metallophosphoesterase
RHEC894_RS17980	COG0494	nUDIX hydrolase
RHEC894_RS17995	COG2318	DinB family
RHEC894_RS18005	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
RHEC894_RS18005	COG0392	lysyltransferase activity
RHEC894_RS18015	COG0668	transmembrane transport
RHEC894_RS18020	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
RHEC894_RS18080	COG0126	phosphoglycerate kinase activity
RHEC894_RS18085	COG3588	fructose-bisphosphate aldolase
RHEC894_RS18090	COG0384	phenazine biosynthesis protein PhzF
RHEC894_RS18110	COG0254	rRNA binding
RHEC894_RS18115	COG1132	(ABC) transporter
RHEC894_RS18125	COG3422	double-strand break repair
RHEC894_RS18150	COG0483	inositol monophosphate 1-phosphatase activity
RHEC894_RS18155	COG2201	protein-glutamate methylesterase activity
RHEC894_RS18165	COG0835	chemotaxis
RHEC894_RS18170	COG0840	transmembrane signaling receptor activity
RHEC894_RS18175	COG0840	transmembrane signaling receptor activity
RHEC894_RS18180	COG0835	chemotaxis
RHEC894_RS18185	COG2198	Histidine kinase
RHEC894_RS18185	COG0643	Histidine kinase
RHEC894_RS18220	COG0640	Transcriptional regulator
RHEC894_RS18235	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
RHEC894_RS18240	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
RHEC894_RS18245	COG0257	Belongs to the bacterial ribosomal protein bL36 family
RHEC894_RS18250	COG0457	Tetratricopeptide repeat
RHEC894_RS18275	COG0583	DNA-binding transcription factor activity
RHEC894_RS18280	COG1942	4-Oxalocrotonate Tautomerase
RHEC894_RS18300	COG0469	pyruvate kinase activity
RHEC894_RS18320	COG3750	Belongs to the UPF0335 family
RHEC894_RS18325	COG3108	Peptidase M15
RHEC894_RS18345	COG0512	Glutamine amidotransferase of anthranilate synthase
RHEC894_RS18345	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
RHEC894_RS18360	COG5310	Homospermidine synthase
RHEC894_RS18375	COG0737	Belongs to the 5'-nucleotidase family
RHEC894_RS18380	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
RHEC894_RS18385	COG0330	HflC and HflK could
RHEC894_RS18405	COG0583	DNA-binding transcription factor activity
RHEC894_RS18420	COG4638	Rieske (2fe-2S)
RHEC894_RS18425	COG1210	Utp--glucose-1-phosphate uridylyltransferase
RHEC894_RS18430	COG2951	lytic endotransglycosylase activity
RHEC894_RS18450	COG0070	glutamate synthase
RHEC894_RS18450	COG0069	glutamate synthase activity
RHEC894_RS18450	COG0067	glutamate synthase
RHEC894_RS18470	COG0071	Belongs to the small heat shock protein (HSP20) family
RHEC894_RS18555	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
RHEC894_RS18580	COG2308	Evidence 4 Homologs of previously reported genes of
RHEC894_RS18580	COG2307	Protein conserved in bacteria
RHEC894_RS18595	COG0058	SHG alpha-glucan phosphorylase activity
RHEC894_RS18600	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
RHEC894_RS18605	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
RHEC894_RS18610	COG0297	glycogen (starch) synthase activity
RHEC894_RS18615	COG0033	Phosphoglucomutase
RHEC894_RS18620	COG1523	belongs to the glycosyl hydrolase 13 family
RHEC894_RS18640	COG0404	The glycine cleavage system catalyzes the degradation of glycine
RHEC894_RS18640	COG0446	pyridine nucleotide-disulphide oxidoreductase
RHEC894_RS18650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RHEC894_RS18670	COG0828	Belongs to the bacterial ribosomal protein bS21 family
RHEC894_RS18680	COG2202	Pas domain
RHEC894_RS18680	COG3920	Histidine kinase
RHEC894_RS18715	COG5001	Diguanylate cyclase
RHEC894_RS18720	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
RHEC894_RS18730	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
RHEC894_RS18735	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
RHEC894_RS18765	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RHEC894_RS18770	COG1609	Transcriptional regulator
RHEC894_RS18775	COG1846	Transcriptional regulator
RHEC894_RS18785	COG0523	cobalamin synthesis protein
RHEC894_RS18840	COG0583	DNA-binding transcription factor activity
RHEC894_RS18870	COG0800	Aldolase
RHEC894_RS18875	COG2954	triphosphatase activity
RHEC894_RS18890	COG1054	Belongs to the UPF0176 family
RHEC894_RS18910	COG0673	inositol 2-dehydrogenase activity
RHEC894_RS18920	COG1879	ABC-type sugar transport system periplasmic component
RHEC894_RS18925	COG1172	Belongs to the binding-protein-dependent transport system permease family
RHEC894_RS18930	COG1129	ABC transporter
RHEC894_RS18935	COG1609	Transcriptional regulator
RHEC894_RS18940	COG2115	Belongs to the xylose isomerase family
RHEC894_RS18945	COG1070	Carbohydrate kinase
RHEC894_RS18950	COG1609	Transcriptional regulator
RHEC894_RS18975	COG1253	flavin adenine dinucleotide binding
RHEC894_RS18980	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
RHEC894_RS18985	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
RHEC894_RS19000	COG0583	DNA-binding transcription factor activity
RHEC894_RS19005	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
RHEC894_RS19010	COG3842	ATPase activity
RHEC894_RS19015	COG1176	ABC-type spermidine putrescine transport system, permease component I
RHEC894_RS19020	COG1177	transmembrane transport
RHEC894_RS19080	COG1595	DNA-templated transcription, initiation
RHEC894_RS19095	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
RHEC894_RS19175	COG1940	carbohydrate kinase activity
RHEC894_RS19200	COG1764	response to oxidative stress
RHEC894_RS19210	COG1028	Short-chain dehydrogenase reductase Sdr
RHEC894_RS19225	COG1129	ABC transporter
RHEC894_RS19235	COG2186	Transcriptional regulator
RHEC894_RS19240	COG4948	Mandelate Racemase Muconate Lactonizing
RHEC894_RS19255	COG1609	Transcriptional regulator
RHEC894_RS19265	COG1028	Short-chain dehydrogenase reductase Sdr
RHEC894_RS19270	COG3386	PFAM SMP-30 Gluconolaconase
RHEC894_RS19280	COG3842	ATPase activity
RHEC894_RS19285	COG0395	ABC-type sugar transport system, permease component
RHEC894_RS19290	COG1175	transmembrane transport
RHEC894_RS19295	COG1653	transport
RHEC894_RS19300	COG1609	Transcriptional regulator
RHEC894_RS19305	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
RHEC894_RS19310	COG0720	synthase
RHEC894_RS19315	COG0602	queuosine metabolic process
RHEC894_RS19325	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RHEC894_RS19335	COG1780	Probably involved in ribonucleotide reductase function
RHEC894_RS19340	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
RHEC894_RS19350	COG0789	Transcriptional regulator
RHEC894_RS19355	COG0493	'glutamate synthase
RHEC894_RS19355	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
RHEC894_RS19365	COG1012	belongs to the aldehyde dehydrogenase family
RHEC894_RS19375	COG1028	Short-chain dehydrogenase reductase Sdr
RHEC894_RS19380	COG0387	Pfam Sodium calcium exchanger
RHEC894_RS19430	COG0387	Pfam Sodium calcium exchanger
RHEC894_RS19465	COG2954	triphosphatase activity
RHEC894_RS19495	COG1566	PFAM secretion protein HlyD family protein
RHEC894_RS19510	COG0628	permease
RHEC894_RS19515	COG0668	transmembrane transport
RHEC894_RS19555	COG0542	response to heat
RHEC894_RS19565	COG2890	protein-(glutamine-N5) methyltransferase activity
RHEC894_RS19570	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
RHEC894_RS19580	COG0527	aspartate kinase activity
RHEC894_RS19585	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
RHEC894_RS19605	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RHEC894_RS19620	COG2226	methyltransferase
RHEC894_RS19620	COG2267	carboxylic ester hydrolase activity
RHEC894_RS19635	COG0494	nUDIX hydrolase
RHEC894_RS19640	COG0456	acetyltransferase
RHEC894_RS19645	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
RHEC894_RS19650	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
RHEC894_RS19655	COG0653	protein targeting
RHEC894_RS19670	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RHEC894_RS19675	COG0667	Aldo Keto reductase
RHEC894_RS19705	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
RHEC894_RS19705	COG4651	solute:proton antiporter activity
RHEC894_RS19735	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
RHEC894_RS19745	COG0300	oxidoreductase activity
RHEC894_RS19760	COG3385	transposase activity
RHEC894_RS19775	COG2086	electron transfer activity
RHEC894_RS19780	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
RHEC894_RS19785	COG1250	3-hydroxyacyl-CoA dehydrogenase
RHEC894_RS19790	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RHEC894_RS19795	COG0165	Argininosuccinate lyase
RHEC894_RS19830	COG2884	Cell division ATP-binding protein ftsE
RHEC894_RS19850	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
RHEC894_RS19865	COG0287	Prephenate dehydrogenase
RHEC894_RS19870	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
RHEC894_RS19875	COG2226	methyltransferase
RHEC894_RS19880	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RHEC894_RS19900	COG0227	Belongs to the bacterial ribosomal protein bL28 family
RHEC894_RS19910	COG0563	adenylate kinase activity
RHEC894_RS19940	COG4536	flavin adenine dinucleotide binding
RHEC894_RS19945	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
RHEC894_RS19950	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
RHEC894_RS19955	COG4974	Belongs to the 'phage' integrase family
RHEC894_RS19960	COG0825	malonyl-CoA metabolic process
RHEC894_RS19970	COG2207	Transcriptional regulator
RHEC894_RS19975	COG2272	Belongs to the type-B carboxylesterase lipase family
RHEC894_RS19980	COG0028	Belongs to the TPP enzyme family
RHEC894_RS19985	COG1522	sequence-specific DNA binding
RHEC894_RS20000	COG1335	isochorismatase
RHEC894_RS20015	COG2207	Transcriptional regulator
RHEC894_RS20020	COG1028	Short-chain dehydrogenase reductase Sdr
RHEC894_RS20025	COG3034	peptidoglycan biosynthetic process
RHEC894_RS20035	COG0523	cobalamin synthesis protein
RHEC894_RS20040	COG1686	Belongs to the peptidase S11 family
RHEC894_RS20090	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
RHEC894_RS20110	COG1175	transmembrane transport
RHEC894_RS20125	COG0156	8-amino-7-oxononanoate synthase activity
RHEC894_RS20135	COG0729	surface antigen
RHEC894_RS20150	COG0010	Belongs to the arginase family
RHEC894_RS20155	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
RHEC894_RS20160	COG0835	chemotaxis
RHEC894_RS20175	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
RHEC894_RS20185	COG3383	formate dehydrogenase (NAD+) activity
RHEC894_RS20200	COG0583	DNA-binding transcription factor activity
RHEC894_RS20205	COG0640	Transcriptional regulator
RHEC894_RS20210	COG1028	Short-chain dehydrogenase reductase Sdr
RHEC894_RS20235	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RHEC894_RS20240	COG1116	anion transmembrane transporter activity
RHEC894_RS20245	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RHEC894_RS20260	COG0355	proton-transporting ATP synthase activity, rotational mechanism
RHEC894_RS20270	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
RHEC894_RS20275	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
RHEC894_RS20280	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
RHEC894_RS20285	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
RHEC894_RS20300	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RHEC894_RS20315	COG4974	Belongs to the 'phage' integrase family
RHEC894_RS20325	COG3038	cytochrome b561
RHEC894_RS20340	COG1028	Short-chain dehydrogenase reductase Sdr
RHEC894_RS20355	COG0508	dehydrogenase complex catalyzes the overall conversion of
RHEC894_RS20370	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
RHEC894_RS20375	COG0045	succinate-CoA ligase (ADP-forming) activity
RHEC894_RS20380	COG0039	L-malate dehydrogenase activity
RHEC894_RS20385	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
RHEC894_RS20390	COG2845	Protein of unknown function (DUF459)
RHEC894_RS20395	COG3541	Predicted nucleotidyltransferase
RHEC894_RS20425	COG2264	protein methyltransferase activity
RHEC894_RS20440	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
RHEC894_RS20445	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
RHEC894_RS20450	COG0181	hydroxymethylbilane synthase activity
RHEC894_RS20490	COG1872	DUF167
RHEC894_RS20495	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
RHEC894_RS20505	COG1217	gtp-binding protein TYPA
RHEC894_RS20510	COG0339	signal peptide processing
RHEC894_RS20540	COG0137	argininosuccinate synthase activity
RHEC894_RS20545	COG0300	oxidoreductase activity
RHEC894_RS20555	COG1122	ATPase activity
RHEC894_RS20560	COG4120	Belongs to the binding-protein-dependent transport system permease family
RHEC894_RS20570	COG0820	rRNA (adenine-C2-)-methyltransferase activity
RHEC894_RS20580	COG1595	DNA-templated transcription, initiation
RHEC894_RS20590	COG2154	pterin-4-alpha-carbinolamine dehydratase
RHEC894_RS20600	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
RHEC894_RS20610	COG4181	ATPase activity
RHEC894_RS20620	COG0670	Belongs to the BI1 family
RHEC894_RS20640	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
RHEC894_RS20645	COG4133	protoheme IX ABC transporter activity
RHEC894_RS20655	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RHEC894_RS20660	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RHEC894_RS20685	COG2917	probably involved in intracellular septation
RHEC894_RS20690	COG0552	protein localization to endoplasmic reticulum
RHEC894_RS20695	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RHEC894_RS20700	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
RHEC894_RS20715	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
RHEC894_RS20720	COG1605	Chorismate mutase
RHEC894_RS20720	COG0287	Prephenate dehydrogenase
RHEC894_RS20725	COG0228	four-way junction DNA binding
RHEC894_RS20730	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
RHEC894_RS20735	COG0336	Belongs to the RNA methyltransferase TrmD family
RHEC894_RS20740	COG0335	large ribosomal subunit rRNA binding
RHEC894_RS20750	COG0765	amino acid transport
RHEC894_RS20760	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
RHEC894_RS20770	COG0656	L-ascorbic acid biosynthetic process
RHEC894_RS20780	COG0745	RESPONSE REGULATOR receiver
RHEC894_RS20800	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
RHEC894_RS20805	COG1674	ftsk spoiiie
RHEC894_RS20810	COG0004	ammonium transporteR
RHEC894_RS20815	COG0347	Belongs to the P(II) protein family
RHEC894_RS20820	COG1946	Acyl-CoA thioesterase
RHEC894_RS20825	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RHEC894_RS20830	COG2835	tetraacyldisaccharide 4'-kinase activity
RHEC894_RS20855	COG0517	IMP dehydrogenase activity
RHEC894_RS20855	COG0617	tRNA 3'-terminal CCA addition
RHEC894_RS20855	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
RHEC894_RS20860	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
RHEC894_RS20885	COG0405	Gamma-glutamyltransferase
RHEC894_RS20895	COG3842	ATPase activity
RHEC894_RS20915	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RHEC894_RS20920	COG5383	Protein conserved in bacteria
RHEC894_RS20945	COG0438	transferase activity, transferring glycosyl groups
RHEC894_RS20960	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
RHEC894_RS20970	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RHEC894_RS20975	COG1509	lysine 2,3-aminomutase activity
RHEC894_RS20980	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
RHEC894_RS20985	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
RHEC894_RS20995	COG4821	SIS domain
RHEC894_RS21000	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
RHEC894_RS21005	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
RHEC894_RS21010	COG2188	Transcriptional regulator
RHEC894_RS21020	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
RHEC894_RS21025	COG4178	(ABC) transporter
RHEC894_RS21035	COG0488	(ABC) transporter
RHEC894_RS21060	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
RHEC894_RS21065	COG1329	Transcriptional regulator
RHEC894_RS21070	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
RHEC894_RS21075	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
RHEC894_RS21095	COG1028	Short-chain dehydrogenase reductase Sdr
RHEC894_RS21100	COG0183	Belongs to the thiolase family
RHEC894_RS21105	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
RHEC894_RS21115	COG0333	Belongs to the bacterial ribosomal protein bL32 family
RHEC894_RS21130	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RHEC894_RS21135	COG0142	geranyltranstransferase activity
RHEC894_RS21140	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
RHEC894_RS21145	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
RHEC894_RS21150	COG2223	nitrite transmembrane transporter activity
RHEC894_RS21155	COG1349	DNA-binding transcription factor activity
RHEC894_RS21165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RHEC894_RS21170	COG0765	amino acid transport
RHEC894_RS21175	COG1126	abc transporter atp-binding protein
RHEC894_RS21180	COG0431	NADPH-dependent FMN reductase
RHEC894_RS21185	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
RHEC894_RS21195	COG1132	(ABC) transporter
RHEC894_RS21210	COG3459	Glycosyltransferase 36 associated
RHEC894_RS21220	COG4608	Belongs to the ABC transporter superfamily
RHEC894_RS21225	COG0444	Belongs to the ABC transporter superfamily
RHEC894_RS21230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RHEC894_RS21235	COG0601	transmembrane transport
RHEC894_RS21250	COG4211	Belongs to the binding-protein-dependent transport system permease family
RHEC894_RS21255	COG1129	ABC transporter
RHEC894_RS21305	COG4456	Virulence-associated protein
RHEC894_RS21320	COG0261	This protein binds to 23S rRNA in the presence of protein L20
RHEC894_RS21325	COG0211	Belongs to the bacterial ribosomal protein bL27 family
RHEC894_RS21345	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
RHEC894_RS21350	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
RHEC894_RS21355	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
RHEC894_RS21360	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
RHEC894_RS21375	COG0725	ABC transporter, periplasmic molybdate-binding protein
RHEC894_RS21380	COG4149	molybdate abc transporter
RHEC894_RS21385	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
RHEC894_RS21395	COG0799	negative regulation of ribosome biogenesis
RHEC894_RS21400	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
RHEC894_RS21410	COG0793	Belongs to the peptidase S41A family
RHEC894_RS21420	COG0494	nUDIX hydrolase
RHEC894_RS21435	COG0587	DNA-directed DNA polymerase activity
RHEC894_RS21460	COG2301	Belongs to the HpcH HpaI aldolase family
RHEC894_RS21475	COG0066	3-isopropylmalate dehydratase activity
RHEC894_RS21485	COG0473	3-isopropylmalate dehydrogenase activity
RHEC894_RS21490	COG0671	phosphoesterase, PA-phosphatase related
RHEC894_RS21505	COG1136	(ABC) transporter
RHEC894_RS21515	COG1785	Belongs to the alkaline phosphatase family
RHEC894_RS21520	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
RHEC894_RS21530	COG4251	negative regulation of phosphorylation
RHEC894_RS21530	COG2203	Gaf domain
RHEC894_RS21530	COG3706	GGDEF domain
RHEC894_RS21530	COG5001	Diguanylate cyclase
RHEC894_RS21535	COG0288	reversible hydration of carbon dioxide
RHEC894_RS21550	COG2902	Dehydrogenase
RHEC894_RS21555	COG2270	Major facilitator Superfamily
RHEC894_RS21560	COG0138	bifunctional purine biosynthesis protein purh
RHEC894_RS21575	COG0501	Belongs to the peptidase M48B family
RHEC894_RS21585	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RHEC894_RS21610	COG0495	leucyl-tRNA aminoacylation
RHEC894_RS21635	COG0357	Ribosomal RNA small subunit methyltransferase G
RHEC894_RS21640	COG0445	tRNA wobble uridine modification
RHEC894_RS21645	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
RHEC894_RS21650	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
RHEC894_RS21655	COG1981	membrane
RHEC894_RS21660	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
RHEC894_RS21665	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
RHEC894_RS21685	COG1802	Transcriptional regulator
RHEC894_RS21720	COG0488	(ABC) transporter
RHEC894_RS21765	COG4977	sequence-specific DNA binding
RHEC894_RS21775	COG1309	transcriptional regulator
RHEC894_RS21780	COG0583	DNA-binding transcription factor activity
RHEC894_RS21785	COG2223	nitrite transmembrane transporter activity
RHEC894_RS21800	COG0697	spore germination
RHEC894_RS21805	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
RHEC894_RS21805	COG1672	PFAM Archaeal ATPase
RHEC894_RS21825	COG3842	ATPase activity
RHEC894_RS21840	COG0395	ABC-type sugar transport system, permease component
RHEC894_RS21855	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
RHEC894_RS21860	COG1172	Belongs to the binding-protein-dependent transport system permease family
RHEC894_RS21865	COG1172	Belongs to the binding-protein-dependent transport system permease family
RHEC894_RS21870	COG1129	ABC transporter
RHEC894_RS21900	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
RHEC894_RS21905	COG1454	alcohol dehydrogenase
RHEC894_RS21915	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RHEC894_RS21920	COG0747	negative chemotaxis
RHEC894_RS21925	COG0601	transmembrane transport
RHEC894_RS21930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RHEC894_RS21935	COG0444	Belongs to the ABC transporter superfamily
RHEC894_RS21940	COG4608	Belongs to the ABC transporter superfamily
RHEC894_RS21965	COG2323	membrane
RHEC894_RS21970	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
RHEC894_RS22095	COG0596	Alpha beta hydrolase
RHEC894_RS22105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RHEC894_RS22110	COG4172	Belongs to the ABC transporter superfamily
RHEC894_RS22120	COG0625	glutathione transferase activity
RHEC894_RS22125	COG3609	addiction module antidote protein, CC2985 family
RHEC894_RS22135	COG3842	ATPase activity
RHEC894_RS22150	COG0395	ABC-type sugar transport system, permease component
RHEC894_RS22155	COG1175	transmembrane transport
RHEC894_RS22165	COG1802	Transcriptional regulator
RHEC894_RS22170	COG5441	Belongs to the UPF0261 family
RHEC894_RS22175	COG5564	TIM-barrel signal transduction protein
RHEC894_RS22200	COG4459	periplasmic nitrate reductase
RHEC894_RS22205	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
RHEC894_RS22215	COG0243	molybdopterin cofactor binding
RHEC894_RS22225	COG3005	denitrification pathway
RHEC894_RS22230	COG4589	Belongs to the CDS family
RHEC894_RS22250	COG3845	ABC transporter
RHEC894_RS22260	COG1079	Belongs to the binding-protein-dependent transport system permease family
RHEC894_RS22265	COG0402	S-adenosylhomocysteine deaminase activity
RHEC894_RS22270	COG4106	trans-aconitate 2-methyltransferase activity
RHEC894_RS22280	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
RHEC894_RS22290	COG1176	ABC-type spermidine putrescine transport system, permease component I
RHEC894_RS22300	COG3842	ATPase activity
RHEC894_RS22310	COG3842	ATPase activity
RHEC894_RS22315	COG0395	ABC-type sugar transport system, permease component
RHEC894_RS22335	COG0673	inositol 2-dehydrogenase activity
RHEC894_RS22340	COG1609	Transcriptional regulator
RHEC894_RS22360	COG4213	ABC transporter substrate-binding protein
RHEC894_RS22365	COG1129	ABC transporter
RHEC894_RS22370	COG1172	Belongs to the binding-protein-dependent transport system permease family
RHEC894_RS22380	COG0747	negative chemotaxis
RHEC894_RS22390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RHEC894_RS22405	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
RHEC894_RS22415	COG3706	GGDEF domain
RHEC894_RS22425	COG1609	Transcriptional regulator
RHEC894_RS22430	COG0584	glycerophosphoryl diester phosphodiesterase
RHEC894_RS22435	COG3842	ATPase activity
RHEC894_RS22445	COG1175	transmembrane transport
RHEC894_RS22455	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
RHEC894_RS22465	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RHEC894_RS22480	COG4988	ABC transporter
RHEC894_RS22485	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
RHEC894_RS22490	COG1271	oxidase subunit
RHEC894_RS22495	COG1294	oxidase, subunit
RHEC894_RS22515	COG1309	transcriptional regulator
RHEC894_RS22520	COG2226	methyltransferase
RHEC894_RS22525	COG0667	Aldo Keto reductase
RHEC894_RS22535	COG0395	ABC-type sugar transport system, permease component
RHEC894_RS22565	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
RHEC894_RS22590	COG0346	lactoylglutathione lyase activity
RHEC894_RS22595	COG0673	inositol 2-dehydrogenase activity
RHEC894_RS22600	COG0673	inositol 2-dehydrogenase activity
RHEC894_RS22615	COG2764	glyoxalase bleomycin resistance protein dioxygenase
RHEC894_RS22625	COG1309	transcriptional regulator
RHEC894_RS22630	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
RHEC894_RS22630	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
RHEC894_RS22640	COG2011	ABC-type metal ion transport system permease component
RHEC894_RS22650	COG1464	Belongs to the NlpA lipoprotein family
RHEC894_RS22660	COG2223	nitrite transmembrane transporter activity
RHEC894_RS22665	COG1396	sequence-specific DNA binding
RHEC894_RS22680	COG1192	Involved in chromosome partitioning
RHEC894_RS22685	COG1475	DNA binding
RHEC894_RS22690	COG1414	Transcriptional regulator
RHEC894_RS22710	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
RHEC894_RS22810	COG1028	Short-chain dehydrogenase reductase Sdr
RHEC894_RS22840	COG1473	amidohydrolase
RHEC894_RS22855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RHEC894_RS22860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RHEC894_RS22865	COG4215	(ABC) transporter
RHEC894_RS22875	COG1012	belongs to the aldehyde dehydrogenase family
RHEC894_RS22900	COG3938	Belongs to the proline racemase family
RHEC894_RS22905	COG4176	ABC-type proline glycine betaine transport system permease component
RHEC894_RS22910	COG4176	ABC-type proline glycine betaine transport system permease component
RHEC894_RS22915	COG4175	Glycine betaine
RHEC894_RS22915	COG3448	diguanylate cyclase activity
RHEC894_RS22925	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RHEC894_RS22930	COG1012	belongs to the aldehyde dehydrogenase family
RHEC894_RS22935	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RHEC894_RS22980	COG1024	Enoyl-CoA hydratase
RHEC894_RS23010	COG1475	DNA binding
RHEC894_RS23040	COG0583	DNA-binding transcription factor activity
RHEC894_RS23045	COG5489	Protein of unknown function (DUF736)
RHEC894_RS23065	COG3831	ATPase activity
RHEC894_RS23110	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RHEC894_RS23115	COG0519	Catalyzes the synthesis of GMP from XMP
RHEC894_RS23115	COG0518	GMP synthase (glutamine-hydrolyzing) activity
RHEC894_RS23125	COG4770	biotin carboxylase activity
RHEC894_RS23145	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
RHEC894_RS23150	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
RHEC894_RS23155	COG2188	Transcriptional regulator
RHEC894_RS23160	COG2971	BadF BadG BcrA BcrD
RHEC894_RS23170	COG0483	inositol monophosphate 1-phosphatase activity
RHEC894_RS23175	COG1082	Xylose isomerase domain protein TIM barrel
RHEC894_RS23180	COG1178	ABC-type Fe3 transport system permease component
RHEC894_RS23185	COG3842	ATPase activity
RHEC894_RS23190	COG1840	ABC-type Fe3 transport system, periplasmic component
RHEC894_RS23195	COG1940	carbohydrate kinase activity
RHEC894_RS23200	COG1940	carbohydrate kinase activity
RHEC894_RS23215	COG0395	ABC-type sugar transport system, permease component
RHEC894_RS23220	COG0673	inositol 2-dehydrogenase activity
RHEC894_RS23230	COG0840	transmembrane signaling receptor activity
RHEC894_RS23230	COG2972	Histidine kinase
RHEC894_RS23235	COG0747	negative chemotaxis
RHEC894_RS23240	COG0601	transmembrane transport
RHEC894_RS23250	COG4172	Belongs to the ABC transporter superfamily
RHEC894_RS23270	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
RHEC894_RS23275	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RHEC894_RS23290	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
RHEC894_RS23295	COG0288	reversible hydration of carbon dioxide
RHEC894_RS23300	COG1012	belongs to the aldehyde dehydrogenase family
RHEC894_RS23305	COG1172	Belongs to the binding-protein-dependent transport system permease family
RHEC894_RS23310	COG1129	ABC transporter
RHEC894_RS23315	COG1879	ABC-type sugar transport system periplasmic component
RHEC894_RS23320	COG1984	allophanate hydrolase subunit 2
RHEC894_RS23335	COG0511	ligase activity, forming carbon-carbon bonds
RHEC894_RS23340	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
RHEC894_RS23345	COG0583	DNA-binding transcription factor activity
RHEC894_RS23360	COG1176	ABC-type spermidine putrescine transport system, permease component I
RHEC894_RS23385	COG3842	ATPase activity
RHEC894_RS23390	COG0726	polysaccharide deacetylase
RHEC894_RS23400	COG0523	cobalamin synthesis protein
RHEC894_RS23415	COG2972	Histidine kinase
RHEC894_RS23415	COG0840	transmembrane signaling receptor activity
RHEC894_RS23420	COG0583	DNA-binding transcription factor activity
RHEC894_RS23425	COG1902	pentaerythritol trinitrate reductase activity
RHEC894_RS23430	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
RHEC894_RS23435	COG0583	DNA-binding transcription factor activity
RHEC894_RS23445	COG1942	4-Oxalocrotonate Tautomerase
RHEC894_RS23455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RHEC894_RS23465	COG4215	(ABC) transporter
RHEC894_RS23485	COG0010	Belongs to the arginase family
RHEC894_RS23505	COG1028	Short-chain dehydrogenase reductase Sdr
RHEC894_RS23510	COG1028	Short-chain dehydrogenase reductase Sdr
RHEC894_RS23520	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RHEC894_RS23530	COG0022	dehydrogenase e1 component
RHEC894_RS23535	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
RHEC894_RS23540	COG1172	Belongs to the binding-protein-dependent transport system permease family
RHEC894_RS23545	COG1129	ABC transporter
RHEC894_RS23570	COG0395	ABC-type sugar transport system, permease component
RHEC894_RS23575	COG1175	transmembrane transport
RHEC894_RS23580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RHEC894_RS23600	COG1172	Belongs to the binding-protein-dependent transport system permease family
RHEC894_RS23605	COG1129	ABC transporter
RHEC894_RS23645	COG0765	amino acid transport
RHEC894_RS23650	COG1126	abc transporter atp-binding protein
RHEC894_RS23665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RHEC894_RS23670	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
RHEC894_RS23685	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
RHEC894_RS23690	COG1028	Short-chain dehydrogenase reductase Sdr
RHEC894_RS23710	COG1484	DNA-dependent DNA replication
RHEC894_RS23715	COG4584	PFAM Integrase catalytic
RHEC894_RS23730	COG1028	Short-chain dehydrogenase reductase Sdr
RHEC894_RS23735	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
RHEC894_RS23740	COG1609	Transcriptional regulator
RHEC894_RS23745	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
RHEC894_RS23750	COG1881	PFAM PEBP family protein
RHEC894_RS23855	COG0626	cystathionine gamma-synthase activity
RHEC894_RS23860	COG2076	Multidrug Resistance protein
RHEC894_RS23870	COG1012	belongs to the aldehyde dehydrogenase family
RHEC894_RS23885	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
RHEC894_RS23895	COG0583	DNA-binding transcription factor activity
RHEC894_RS23910	COG0251	oxidation-reduction process
RHEC894_RS23915	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RHEC894_RS23930	COG0318	PFAM AMP-dependent synthetase and ligase
RHEC894_RS23940	COG1802	Transcriptional regulator
RHEC894_RS23965	COG3701	Conjugal transfer protein
RHEC894_RS23970	COG3846	protein secretion by the type IV secretion system
RHEC894_RS23980	COG5314	conjugation
RHEC894_RS23985	COG3451	type IV secretory pathway VirB4
RHEC894_RS24000	COG4962	Type ii secretion system protein e
RHEC894_RS24010	COG1192	Involved in chromosome partitioning
RHEC894_RS24015	COG1475	DNA binding
RHEC894_RS24020	COG0640	Transcriptional regulator
RHEC894_RS24045	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
RHEC894_RS24120	COG1078	dGTPase activity
RHEC894_RS24160	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RHEC894_RS24165	COG0071	Belongs to the small heat shock protein (HSP20) family
RHEC894_RS24170	COG0071	Belongs to the small heat shock protein (HSP20) family
RHEC894_RS24185	COG0438	transferase activity, transferring glycosyl groups
RHEC894_RS24200	COG0459	protein refolding
RHEC894_RS24205	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
RHEC894_RS24210	COG5425	PFAM Usg family protein
RHEC894_RS24220	COG0071	Belongs to the small heat shock protein (HSP20) family
RHEC894_RS24245	COG1335	isochorismatase
RHEC894_RS24250	COG0596	Alpha beta hydrolase
RHEC894_RS24260	COG0596	Alpha beta hydrolase
RHEC894_RS24270	COG3177	Filamentation induced by cAMP protein fic
RHEC894_RS24275	COG0179	Fumarylacetoacetate (FAA) hydrolase
RHEC894_RS24285	COG1609	Transcriptional regulator
RHEC894_RS24310	COG0148	phosphopyruvate hydratase activity
RHEC894_RS24325	COG1063	alcohol dehydrogenase
RHEC894_RS24330	COG0431	NADPH-dependent FMN reductase
RHEC894_RS24340	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RHEC894_RS24345	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
RHEC894_RS24350	COG0583	DNA-binding transcription factor activity
RHEC894_RS24355	COG1960	acyl-CoA dehydrogenase activity
RHEC894_RS24360	COG1250	3-hydroxyacyl-CoA dehydrogenase
RHEC894_RS24375	COG2086	electron transfer activity
RHEC894_RS24385	COG1902	pentaerythritol trinitrate reductase activity
RHEC894_RS24395	COG0604	alcohol dehydrogenase
RHEC894_RS24400	COG1309	transcriptional regulator
RHEC894_RS24405	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RHEC894_RS24510	COG5489	Protein of unknown function (DUF736)
RHEC894_RS24515	COG0776	regulation of translation
RHEC894_RS24530	COG3831	ATPase activity
RHEC894_RS24540	COG3077	Addiction module antitoxin, RelB DinJ family
RHEC894_RS24590	COG4584	PFAM Integrase catalytic
RHEC894_RS24640	COG4669	(LipO)protein
RHEC894_RS24660	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
RHEC894_RS24665	COG4790	Type iii secretion
RHEC894_RS24670	COG1987	bacterial-type flagellum assembly
RHEC894_RS24675	COG4791	protein targeting
RHEC894_RS24680	COG4792	protein secretion
RHEC894_RS24685	COG5297	Belongs to the glycosyl hydrolase family 6
RHEC894_RS24690	COG4789	Type iii secretion
RHEC894_RS24710	COG1396	sequence-specific DNA binding
RHEC894_RS24755	COG0596	Alpha beta hydrolase
RHEC894_RS24760	COG1879	ABC-type sugar transport system periplasmic component
RHEC894_RS24765	COG1129	ABC transporter
RHEC894_RS24770	COG1172	Belongs to the binding-protein-dependent transport system permease family
RHEC894_RS24775	COG1172	Belongs to the binding-protein-dependent transport system permease family
RHEC894_RS24800	COG0840	transmembrane signaling receptor activity
RHEC894_RS24800	COG2972	Histidine kinase
RHEC894_RS24825	COG0840	transmembrane signaling receptor activity
RHEC894_RS24825	COG2972	Histidine kinase
RHEC894_RS24830	COG4213	ABC transporter substrate-binding protein
RHEC894_RS24845	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RHEC894_RS24850	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
RHEC894_RS24860	COG2186	Transcriptional regulator
RHEC894_RS24875	COG1028	Short-chain dehydrogenase reductase Sdr
RHEC894_RS24880	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RHEC894_RS24885	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RHEC894_RS24890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RHEC894_RS24895	COG1879	ABC-type sugar transport system periplasmic component
RHEC894_RS24900	COG0436	Aminotransferase
RHEC894_RS24915	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RHEC894_RS24915	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RHEC894_RS24930	COG1879	ABC-type sugar transport system periplasmic component
RHEC894_RS24935	COG1129	ABC transporter
RHEC894_RS24940	COG1172	Belongs to the binding-protein-dependent transport system permease family
RHEC894_RS24960	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RHEC894_RS24970	COG0840	transmembrane signaling receptor activity
RHEC894_RS24980	COG0459	protein refolding
RHEC894_RS25010	COG3838	Conjugal transfer protein Trbc
RHEC894_RS25015	COG3702	type iv secretory pathway
RHEC894_RS25020	COG3451	type IV secretory pathway VirB4
RHEC894_RS25035	COG3704	protein secretion by the type IV secretion system
RHEC894_RS25045	COG3736	Type IV secretory pathway, component VirB8
RHEC894_RS25050	COG3504	Conjugal transfer protein
RHEC894_RS25055	COG2948	multi-organism process
RHEC894_RS25060	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
RHEC894_RS25100	COG3831	ATPase activity
RHEC894_RS25115	COG2161	toxin-antitoxin pair type II binding
RHEC894_RS25120	COG3505	Type IV secretory pathway VirD4
RHEC894_RS25170	COG1396	sequence-specific DNA binding
RHEC894_RS25175	COG2843	Capsule synthesis protein
RHEC894_RS25235	COG5490	Phasin protein
RHEC894_RS25240	COG5490	Phasin protein
RHEC894_RS25380	COG0535	radical SAM domain protein
RHEC894_RS25400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RHEC894_RS25475	COG2801	Transposase and inactivated derivatives
RHEC894_RS25510	COG1433	Dinitrogenase iron-molybdenum cofactor
RHEC894_RS25515	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
RHEC894_RS25525	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
RHEC894_RS25530	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
RHEC894_RS25555	COG3328	transposase activity
RHEC894_RS25570	COG4372	Transposase
RHEC894_RS25580	COG3328	transposase activity
RHEC894_RS25600	COG1028	Short-chain dehydrogenase reductase Sdr
RHEC894_RS25605	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
RHEC894_RS25615	COG2124	cytochrome p450
RHEC894_RS25635	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
RHEC894_RS25650	COG0316	Belongs to the HesB IscA family
RHEC894_RS25660	COG1104	cysteine desulfurase activity
RHEC894_RS25675	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
RHEC894_RS25680	COG0644	oxidoreductase
RHEC894_RS25695	COG0535	radical SAM domain protein
RHEC894_RS25700	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
RHEC894_RS25705	COG5554	nitrogen fixation
RHEC894_RS25710	COG5554	nitrogen fixation
RHEC894_RS25720	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
RHEC894_RS25770	COG0142	geranyltranstransferase activity
RHEC894_RS25775	COG1304	FMN binding
RHEC894_RS25785	COG1657	PFAM Prenyltransferase squalene oxidase
RHEC894_RS25800	COG1028	Short-chain dehydrogenase reductase Sdr
RHEC894_RS25805	COG2124	cytochrome p450
RHEC894_RS25810	COG2124	cytochrome p450
RHEC894_RS25850	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
RHEC894_RS25855	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RHEC894_RS25890	COG0275	rRNA processing
RHEC894_RS25900	COG1484	DNA-dependent DNA replication
RHEC894_RS26020	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RHEC894_RS26040	COG5490	Phasin protein
RHEC894_RS26050	COG3383	formate dehydrogenase (NAD+) activity
RHEC894_RS26055	COG5420	small protein containing a coiled-coil domain
RHEC894_RS26065	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
RHEC894_RS26070	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
RHEC894_RS26075	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
RHEC894_RS26115	COG2801	Transposase and inactivated derivatives
RHEC894_RS26165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RHEC894_RS26210	COG2274	protein secretion by the type I secretion system
RHEC894_RS26235	COG3594	Acyltransferase
RHEC894_RS26245	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
RHEC894_RS26250	COG5490	Phasin protein
RHEC894_RS26265	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
RHEC894_RS26285	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
RHEC894_RS26295	COG3838	Conjugal transfer protein Trbc
RHEC894_RS26300	COG3916	Acyl-homoserine-lactone synthase
RHEC894_RS26310	COG3916	Acyl-homoserine-lactone synthase
RHEC894_RS26315	COG1192	Involved in chromosome partitioning
RHEC894_RS26320	COG1475	DNA binding
RHEC894_RS26325	COG0640	Transcriptional regulator
RHEC894_RS26335	COG0670	Belongs to the BI1 family
RHEC894_RS26370	COG4953	penicillin-binding protein 1C
RHEC894_RS26375	COG2373	Large extracellular alpha-helical protein
RHEC894_RS26380	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
RHEC894_RS26400	COG2814	Major facilitator Superfamily
RHEC894_RS26410	COG1609	Transcriptional regulator
RHEC894_RS26440	COG4941	Belongs to the sigma-70 factor family
RHEC894_RS26445	COG1132	(ABC) transporter
RHEC894_RS26450	COG1132	(ABC) transporter
RHEC894_RS26470	COG4191	Histidine kinase
RHEC894_RS26470	COG0784	Response regulator, receiver
RHEC894_RS26480	COG3346	SURF1 family
RHEC894_RS26485	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
RHEC894_RS26490	COG1845	cytochrome c oxidase, subunit III
RHEC894_RS26495	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
RHEC894_RS26500	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
RHEC894_RS26525	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
RHEC894_RS26530	COG1522	sequence-specific DNA binding
RHEC894_RS26540	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RHEC894_RS26540	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RHEC894_RS26565	COG0300	oxidoreductase activity
RHEC894_RS26580	COG2378	regulation of single-species biofilm formation
RHEC894_RS26610	COG0747	negative chemotaxis
RHEC894_RS26640	COG5265	(ABC) transporter
RHEC894_RS26665	COG0714	Associated with various cellular activities
RHEC894_RS26685	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
RHEC894_RS26690	COG3474	cytochrome
RHEC894_RS26720	COG1234	tRNA 3'-trailer cleavage
RHEC894_RS26735	COG1082	Xylose isomerase domain protein TIM barrel
RHEC894_RS26735	COG3185	4-Hydroxyphenylpyruvate dioxygenase
RHEC894_RS26755	COG0765	amino acid transport
RHEC894_RS26760	COG1126	abc transporter atp-binding protein
RHEC894_RS26770	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
RHEC894_RS26785	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
RHEC894_RS26790	COG3485	protocatechuate 3,4-dioxygenase
RHEC894_RS26795	COG3485	protocatechuate 3,4-dioxygenase
RHEC894_RS26800	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RHEC894_RS26805	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
RHEC894_RS26815	COG0583	DNA-binding transcription factor activity
RHEC894_RS26825	COG5654	RES domain protein
RHEC894_RS26840	COG3384	dioxygenase
RHEC894_RS26865	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
RHEC894_RS26870	COG2223	nitrite transmembrane transporter activity
RHEC894_RS26890	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
RHEC894_RS26905	COG2986	histidine ammonia-lyase
RHEC894_RS26910	COG1228	amidohydrolase
RHEC894_RS26915	COG0402	S-adenosylhomocysteine deaminase activity
RHEC894_RS26925	COG2188	Transcriptional regulator
RHEC894_RS26950	COG2986	histidine ammonia-lyase
RHEC894_RS26960	COG0671	phosphoesterase, PA-phosphatase related
RHEC894_RS27005	COG1486	melibiose metabolic process
RHEC894_RS27010	COG0747	negative chemotaxis
RHEC894_RS27015	COG0601	transmembrane transport
RHEC894_RS27020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RHEC894_RS27025	COG4172	Belongs to the ABC transporter superfamily
RHEC894_RS27030	COG1486	melibiose metabolic process
RHEC894_RS27085	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
RHEC894_RS27100	COG1595	DNA-templated transcription, initiation
RHEC894_RS27160	COG1136	(ABC) transporter
RHEC894_RS27160	COG0577	efflux transmembrane transporter activity
RHEC894_RS27175	COG0642	Histidine kinase
RHEC894_RS27180	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
RHEC894_RS27185	COG2076	Multidrug Resistance protein
RHEC894_RS27195	COG1647	Serine aminopeptidase, S33
RHEC894_RS27205	COG2076	Multidrug Resistance protein
RHEC894_RS27215	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
RHEC894_RS27220	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
RHEC894_RS27245	COG4608	Belongs to the ABC transporter superfamily
RHEC894_RS27250	COG0444	Belongs to the ABC transporter superfamily
RHEC894_RS27255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RHEC894_RS27295	COG1414	Transcriptional regulator
RHEC894_RS27300	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
RHEC894_RS27300	COG1672	PFAM Archaeal ATPase
RHEC894_RS27330	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
RHEC894_RS27480	COG2186	Transcriptional regulator
RHEC894_RS27485	COG0626	cystathionine gamma-synthase activity
RHEC894_RS27505	COG0395	ABC-type sugar transport system, permease component
RHEC894_RS27510	COG3842	ATPase activity
RHEC894_RS27520	COG1309	transcriptional regulator
RHEC894_RS27525	COG0300	oxidoreductase activity
RHEC894_RS27535	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
RHEC894_RS27540	COG4208	sulfate ABC transporter
RHEC894_RS27550	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
RHEC894_RS27570	COG2205	protein histidine kinase activity
RHEC894_RS27575	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
RHEC894_RS27580	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
RHEC894_RS27585	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
RHEC894_RS27605	COG1063	alcohol dehydrogenase
RHEC894_RS27615	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RHEC894_RS27625	COG1960	acyl-CoA dehydrogenase activity
RHEC894_RS27680	COG1120	ATPase activity
RHEC894_RS27690	COG1070	Carbohydrate kinase
RHEC894_RS27705	COG1172	Belongs to the binding-protein-dependent transport system permease family
RHEC894_RS27725	COG1028	Short-chain dehydrogenase reductase Sdr
RHEC894_RS27725	COG3347	Dehydrogenase
RHEC894_RS27730	COG4952	isomerase
RHEC894_RS27735	COG3964	amidohydrolase
RHEC894_RS27750	COG1028	Short-chain dehydrogenase reductase Sdr
RHEC894_RS27800	COG3119	arylsulfatase activity
RHEC894_RS27805	COG0583	DNA-binding transcription factor activity
RHEC894_RS27830	COG4608	Belongs to the ABC transporter superfamily
RHEC894_RS27835	COG0444	Belongs to the ABC transporter superfamily
RHEC894_RS27840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RHEC894_RS27855	COG1472	Belongs to the glycosyl hydrolase 3 family
RHEC894_RS27865	COG0351	phosphomethylpyrimidine kinase
RHEC894_RS27870	COG0352	thiamine-phosphate diphosphorylase activity
RHEC894_RS27885	COG0747	negative chemotaxis
RHEC894_RS27895	COG0601	transmembrane transport
RHEC894_RS27910	COG1921	L-seryl-tRNASec selenium transferase activity
RHEC894_RS27920	COG3257	ureidoglycine aminohydrolase activity
RHEC894_RS27930	COG2186	Transcriptional regulator
RHEC894_RS27945	COG1027	Aspartate ammonia-lyase
RHEC894_RS27960	COG2813	Specifically methylates the guanine in position
RHEC894_RS27965	COG3938	Belongs to the proline racemase family
RHEC894_RS27975	COG4585	Histidine kinase
RHEC894_RS27980	COG1879	ABC-type sugar transport system periplasmic component
RHEC894_RS27985	COG1129	ABC transporter
RHEC894_RS27990	COG1172	Belongs to the binding-protein-dependent transport system permease family
RHEC894_RS28010	COG1793	dna ligase
RHEC894_RS28030	COG0251	oxidation-reduction process
RHEC894_RS28045	COG0395	ABC-type sugar transport system, permease component
RHEC894_RS28050	COG1175	transmembrane transport
RHEC894_RS28060	COG3842	ATPase activity
RHEC894_RS28065	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RHEC894_RS28070	COG2186	Transcriptional regulator
RHEC894_RS28080	COG3273	potassium ion transport
RHEC894_RS28080	COG0471	metal ion transport
RHEC894_RS28110	COG0673	inositol 2-dehydrogenase activity
RHEC894_RS28120	COG0395	ABC-type sugar transport system, permease component
RHEC894_RS28130	COG3842	ATPase activity
RHEC894_RS28145	COG3385	transposase activity
RHEC894_RS28170	COG1737	Transcriptional regulator
RHEC894_RS28170	COG0837	glucose binding
RHEC894_RS28175	COG1028	Short-chain dehydrogenase reductase Sdr
RHEC894_RS28195	COG1473	amidohydrolase
RHEC894_RS28210	COG0604	alcohol dehydrogenase
RHEC894_RS28210	COG3321	synthase
RHEC894_RS28225	COG4172	Belongs to the ABC transporter superfamily
RHEC894_RS28230	COG0444	Belongs to the ABC transporter superfamily
RHEC894_RS28235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RHEC894_RS28240	COG0601	transmembrane transport
RHEC894_RS28265	COG3459	Glycosyltransferase 36 associated
RHEC894_RS28270	COG2186	Transcriptional regulator
RHEC894_RS28275	COG1028	Short-chain dehydrogenase reductase Sdr
RHEC894_RS28280	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
RHEC894_RS28300	COG0667	Aldo Keto reductase
RHEC894_RS28310	COG0404	The glycine cleavage system catalyzes the degradation of glycine
RHEC894_RS28325	COG2894	cell division
RHEC894_RS28330	COG0850	regulation of cytokinetic process
RHEC894_RS28335	COG0840	transmembrane signaling receptor activity
RHEC894_RS28350	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RHEC894_RS28360	COG0404	The glycine cleavage system catalyzes the degradation of glycine
RHEC894_RS28375	COG1566	PFAM secretion protein HlyD family protein
RHEC894_RS28395	COG1028	Short-chain dehydrogenase reductase Sdr
RHEC894_RS28410	COG1175	transmembrane transport
RHEC894_RS28415	COG0395	ABC-type sugar transport system, permease component
RHEC894_RS28420	COG1653	transport
RHEC894_RS28430	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
RHEC894_RS28445	COG0583	DNA-binding transcription factor activity
RHEC894_RS28450	COG0473	3-isopropylmalate dehydrogenase activity
RHEC894_RS28470	COG0069	glutamate synthase activity
RHEC894_RS28475	COG2218	PFAM glutamate synthase alpha subunit domain protein
RHEC894_RS28480	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
RHEC894_RS28490	COG4977	sequence-specific DNA binding
RHEC894_RS28495	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RHEC894_RS28500	COG4311	Sarcosine oxidase, delta subunit
RHEC894_RS28505	COG0446	pyridine nucleotide-disulphide oxidoreductase
RHEC894_RS28505	COG0404	The glycine cleavage system catalyzes the degradation of glycine
RHEC894_RS28520	COG4650	regulator
RHEC894_RS28550	COG1902	pentaerythritol trinitrate reductase activity
RHEC894_RS28560	COG2814	Major facilitator Superfamily
RHEC894_RS28570	COG0746	molybdenum cofactor guanylyltransferase activity
RHEC894_RS28585	COG2080	2 iron, 2 sulfur cluster binding
RHEC894_RS28590	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
RHEC894_RS28595	COG1529	Aldehyde oxidase and xanthine dehydrogenase
RHEC894_RS28600	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
RHEC894_RS28685	COG1028	Short-chain dehydrogenase reductase Sdr
RHEC894_RS28695	COG1902	pentaerythritol trinitrate reductase activity
RHEC894_RS28700	COG0583	DNA-binding transcription factor activity
RHEC894_RS28715	COG0697	spore germination
RHEC894_RS28775	COG3385	transposase activity
RHEC894_RS28795	COG4948	Mandelate Racemase Muconate Lactonizing
RHEC894_RS28800	COG1028	Short-chain dehydrogenase reductase Sdr
RHEC894_RS28820	COG1396	sequence-specific DNA binding
RHEC894_RS28850	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
RHEC894_RS28855	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
RHEC894_RS28865	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
RHEC894_RS28885	COG1609	Transcriptional regulator
RHEC894_RS28940	COG1192	Involved in chromosome partitioning
RHEC894_RS28945	COG1475	DNA binding
RHEC894_RS28950	COG1414	Transcriptional regulator
RHEC894_RS28960	COG3311	Transcriptional regulator
RHEC894_RS28965	COG0840	transmembrane signaling receptor activity
RHEC894_RS28965	COG2972	Histidine kinase
RHEC894_RS28970	COG1858	cytochrome C peroxidase
RHEC894_RS28985	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
RHEC894_RS29020	COG2197	response regulator
RHEC894_RS29040	COG3842	ATPase activity
RHEC894_RS29070	COG1733	regulation of RNA biosynthetic process
RHEC894_RS29075	COG3321	synthase
RHEC894_RS29075	COG0604	alcohol dehydrogenase
RHEC894_RS29075	COG1028	Short-chain dehydrogenase reductase Sdr
RHEC894_RS29085	COG0318	PFAM AMP-dependent synthetase and ligase
RHEC894_RS29090	COG0183	Belongs to the thiolase family
RHEC894_RS29140	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
RHEC894_RS29195	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RHEC894_RS29205	COG0297	glycogen (starch) synthase activity
RHEC894_RS29210	COG0438	transferase activity, transferring glycosyl groups
RHEC894_RS29215	COG1215	transferase activity, transferring glycosyl groups
RHEC894_RS29240	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RHEC894_RS29245	COG1442	glycosyl transferase family 8
RHEC894_RS29265	COG0673	inositol 2-dehydrogenase activity
RHEC894_RS29285	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
RHEC894_RS29305	COG0523	cobalamin synthesis protein
RHEC894_RS29320	COG1028	Short-chain dehydrogenase reductase Sdr
RHEC894_RS29325	COG0583	DNA-binding transcription factor activity
RHEC894_RS29335	COG0523	cobalamin synthesis protein
RHEC894_RS29345	COG2274	protein secretion by the type I secretion system
RHEC894_RS29375	COG2132	Multicopper oxidase
RHEC894_RS29380	COG4221	oxidoreductase activity
RHEC894_RS29385	COG1028	Short-chain dehydrogenase reductase Sdr
RHEC894_RS29390	COG0277	FAD linked oxidase domain protein
RHEC894_RS29390	COG0247	lactate metabolic process
RHEC894_RS29395	COG2186	Transcriptional regulator
RHEC894_RS29400	COG0028	Belongs to the TPP enzyme family
RHEC894_RS29410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RHEC894_RS29415	COG0436	Aminotransferase
RHEC894_RS29460	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
RHEC894_RS29465	COG1846	Transcriptional regulator
RHEC894_RS29475	COG1012	belongs to the aldehyde dehydrogenase family
RHEC894_RS29500	COG0411	ABC transporter
RHEC894_RS29535	COG3971	2-oxopent-4-enoate hydratase activity
RHEC894_RS29540	COG0179	Fumarylacetoacetate (FAA) hydrolase
RHEC894_RS29560	COG1012	belongs to the aldehyde dehydrogenase family
RHEC894_RS29590	COG5441	Belongs to the UPF0261 family
RHEC894_RS29595	COG1414	Transcriptional regulator
RHEC894_RS29600	COG0531	amino acid
RHEC894_RS29605	COG1012	belongs to the aldehyde dehydrogenase family
RHEC894_RS29610	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RHEC894_RS29635	COG0517	IMP dehydrogenase activity
RHEC894_RS29645	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
RHEC894_RS29685	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RHEC894_RS29705	COG2151	metal-sulfur cluster biosynthetic enzyme
RHEC894_RS29725	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RHEC894_RS29745	COG0745	RESPONSE REGULATOR receiver
RHEC894_RS29750	COG0642	Histidine kinase
RHEC894_RS29770	COG0784	Response regulator, receiver
RHEC894_RS29770	COG4191	Histidine kinase
RHEC894_RS29775	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RHEC894_RS29830	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
RHEC894_RS29835	COG0517	IMP dehydrogenase activity
RHEC894_RS29840	COG0156	8-amino-7-oxononanoate synthase activity
RHEC894_RS29860	COG1522	sequence-specific DNA binding
RHEC894_RS29865	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
RHEC894_RS29870	COG1473	amidohydrolase
RHEC894_RS29880	COG3618	amidohydrolase
RHEC894_RS29885	COG1879	ABC-type sugar transport system periplasmic component
RHEC894_RS29890	COG1172	Belongs to the binding-protein-dependent transport system permease family
RHEC894_RS29895	COG1129	ABC transporter
RHEC894_RS29900	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
RHEC894_RS29905	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
RHEC894_RS29910	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
RHEC894_RS29915	COG3958	Transketolase
RHEC894_RS29920	COG3959	Transketolase, thiamine diphosphate binding domain
RHEC894_RS29925	COG1028	Short-chain dehydrogenase reductase Sdr
RHEC894_RS29930	COG0583	DNA-binding transcription factor activity
RHEC894_RS29935	COG0583	DNA-binding transcription factor activity
RHEC894_RS29945	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
RHEC894_RS29960	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RHEC894_RS29970	COG0601	transmembrane transport
RHEC894_RS29980	COG4172	Belongs to the ABC transporter superfamily
RHEC894_RS29985	COG1414	Transcriptional regulator
RHEC894_RS29990	COG0673	inositol 2-dehydrogenase activity
RHEC894_RS30000	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RHEC894_RS30015	COG0346	lactoylglutathione lyase activity
RHEC894_RS30035	COG1349	DNA-binding transcription factor activity
RHEC894_RS30040	COG1027	Aspartate ammonia-lyase
RHEC894_RS30065	COG2223	nitrite transmembrane transporter activity
RHEC894_RS30085	COG0395	ABC-type sugar transport system, permease component
RHEC894_RS30090	COG1175	transmembrane transport
RHEC894_RS30095	COG1653	transport
RHEC894_RS30100	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
RHEC894_RS30105	COG0028	Belongs to the TPP enzyme family
RHEC894_RS30110	COG0483	inositol monophosphate 1-phosphatase activity
RHEC894_RS30125	COG2515	1-aminocyclopropane-1-carboxylate deaminase
RHEC894_RS30130	COG2207	Transcriptional regulator
RHEC894_RS30140	COG1126	abc transporter atp-binding protein
RHEC894_RS30145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RHEC894_RS30150	COG0765	amino acid transport
RHEC894_RS30180	COG2186	Transcriptional regulator
RHEC894_RS30195	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RHEC894_RS30205	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RHEC894_RS30230	COG1172	Belongs to the binding-protein-dependent transport system permease family
RHEC894_RS30235	COG1129	ABC transporter
RHEC894_RS30260	COG0765	amino acid transport
RHEC894_RS30275	COG2186	Transcriptional regulator
RHEC894_RS30285	COG0765	amino acid transport
RHEC894_RS30290	COG0765	amino acid transport
RHEC894_RS30310	COG1309	transcriptional regulator
RHEC894_RS30320	COG1749	Flagellar hook protein flgE
RHEC894_RS30360	COG0840	transmembrane signaling receptor activity
RHEC894_RS30365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RHEC894_RS30370	COG3833	ABC-type maltose transport systems, permease component
RHEC894_RS30375	COG1175	transmembrane transport
RHEC894_RS30390	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RHEC894_RS30395	COG1414	Transcriptional regulator
RHEC894_RS30400	COG1475	DNA binding
RHEC894_RS30405	COG1192	Involved in chromosome partitioning
RHEC894_RS30415	COG4191	Histidine kinase
RHEC894_RS30420	COG4566	intracellular signal transduction
RHEC894_RS30425	COG0745	RESPONSE REGULATOR receiver
RHEC894_RS30430	COG4566	intracellular signal transduction
RHEC894_RS30445	COG4948	Mandelate Racemase Muconate Lactonizing
RHEC894_RS30455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RHEC894_RS30460	COG0601	transmembrane transport
RHEC894_RS30465	COG0747	negative chemotaxis
RHEC894_RS30470	COG2186	Transcriptional regulator
RHEC894_RS30475	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RHEC894_RS30485	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RHEC894_RS30490	COG0747	negative chemotaxis
RHEC894_RS30495	COG0601	transmembrane transport
RHEC894_RS30500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RHEC894_RS30505	COG0444	Belongs to the ABC transporter superfamily
RHEC894_RS30510	COG4608	Belongs to the ABC transporter superfamily
RHEC894_RS30525	COG1278	Cold shock
RHEC894_RS30540	COG0318	PFAM AMP-dependent synthetase and ligase
RHEC894_RS30550	COG1802	Transcriptional regulator
RHEC894_RS30555	COG0697	spore germination
RHEC894_RS30575	COG0392	lysyltransferase activity
RHEC894_RS30585	COG2972	Histidine kinase
RHEC894_RS30585	COG0840	transmembrane signaling receptor activity
RHEC894_RS30625	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
RHEC894_RS30650	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
RHEC894_RS30690	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RHEC894_RS30695	COG1120	ATPase activity
RHEC894_RS30705	COG1448	Aminotransferase
RHEC894_RS30710	COG0028	Belongs to the TPP enzyme family
RHEC894_RS30715	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
RHEC894_RS30720	COG0366	Alpha amylase catalytic
RHEC894_RS30725	COG0366	Alpha amylase catalytic
RHEC894_RS30735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RHEC894_RS30745	COG0598	Magnesium transport protein CorA
RHEC894_RS30750	COG0840	transmembrane signaling receptor activity
RHEC894_RS30755	COG1953	Uracil, thiamine, allantoin
RHEC894_RS30775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RHEC894_RS30780	COG1309	transcriptional regulator
RHEC894_RS30785	COG1609	Transcriptional regulator
RHEC894_RS30790	COG2207	Transcriptional regulator
RHEC894_RS30800	COG0395	ABC-type sugar transport system, permease component
RHEC894_RS30805	COG1175	transmembrane transport
RHEC894_RS30820	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
RHEC894_RS30840	COG0730	response to heat
RHEC894_RS30860	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RHEC894_RS30860	COG3453	Protein conserved in bacteria
RHEC894_RS30880	COG0702	epimerase
RHEC894_RS30890	COG0840	transmembrane signaling receptor activity
RHEC894_RS30900	COG0395	ABC-type sugar transport system, permease component
RHEC894_RS30905	COG1175	transmembrane transport
RHEC894_RS30925	COG2186	Transcriptional regulator
RHEC894_RS30930	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RHEC894_RS30940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RHEC894_RS30975	COG1175	transmembrane transport
RHEC894_RS30980	COG0395	ABC-type sugar transport system, permease component
RHEC894_RS30990	COG3842	ATPase activity
RHEC894_RS31070	COG0473	3-isopropylmalate dehydrogenase activity
RHEC894_RS31075	COG0235	Class ii aldolase
RHEC894_RS31080	COG1609	Transcriptional regulator
RHEC894_RS31090	COG2084	Dehydrogenase
RHEC894_RS31095	COG3622	Belongs to the hyi family
RHEC894_RS31100	COG3395	kinase activity
RHEC894_RS31115	COG0601	transmembrane transport
RHEC894_RS31120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RHEC894_RS31135	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
RHEC894_RS31140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RHEC894_RS31155	COG0840	transmembrane signaling receptor activity
RHEC894_RS31170	COG1522	sequence-specific DNA binding
RHEC894_RS31175	COG1733	regulation of RNA biosynthetic process
RHEC894_RS31185	COG1028	Short-chain dehydrogenase reductase Sdr
RHEC894_RS31195	COG0583	DNA-binding transcription factor activity
RHEC894_RS31205	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RHEC894_RS31210	COG0006	proline dipeptidase activity
RHEC894_RS31220	COG3938	Belongs to the proline racemase family
RHEC894_RS31225	COG4176	ABC-type proline glycine betaine transport system permease component
RHEC894_RS31230	COG4176	ABC-type proline glycine betaine transport system permease component
RHEC894_RS31235	COG4175	Glycine betaine
RHEC894_RS31235	COG3448	diguanylate cyclase activity
RHEC894_RS31245	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RHEC894_RS31250	COG1012	belongs to the aldehyde dehydrogenase family
RHEC894_RS31255	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RHEC894_RS31260	COG1802	Transcriptional regulator
RHEC894_RS31265	COG3791	Glutathione-dependent formaldehyde-activating
RHEC894_RS31270	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
RHEC894_RS31275	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
RHEC894_RS31285	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
RHEC894_RS31290	COG2086	electron transfer activity
RHEC894_RS31300	COG0446	pyridine nucleotide-disulphide oxidoreductase
RHEC894_RS31300	COG1902	pentaerythritol trinitrate reductase activity
RHEC894_RS31310	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
RHEC894_RS31320	COG4176	ABC-type proline glycine betaine transport system permease component
RHEC894_RS31335	COG3708	Transcriptional regulator
RHEC894_RS31335	COG2207	Transcriptional regulator
RHEC894_RS31345	COG0243	molybdopterin cofactor binding
RHEC894_RS31350	COG4251	negative regulation of phosphorylation
RHEC894_RS31350	COG5001	Diguanylate cyclase
RHEC894_RS31350	COG3706	GGDEF domain
RHEC894_RS31350	COG2203	Gaf domain
RHEC894_RS31355	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RHEC894_RS31365	COG1609	Transcriptional regulator
RHEC894_RS31370	COG0395	ABC-type sugar transport system, permease component
RHEC894_RS31375	COG1175	transmembrane transport
RHEC894_RS31385	COG3842	ATPase activity
RHEC894_RS31390	COG3264	Mechanosensitive ion channel
RHEC894_RS31390	COG1511	domain protein
RHEC894_RS31395	COG5001	Diguanylate cyclase
RHEC894_RS31405	COG1012	belongs to the aldehyde dehydrogenase family
RHEC894_RS31415	COG1024	Enoyl-CoA hydratase
RHEC894_RS31435	COG0583	DNA-binding transcription factor activity
RHEC894_RS31475	COG4953	penicillin-binding protein 1C
RHEC894_RS31485	COG3385	transposase activity
RHEC894_RS31515	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
RHEC894_RS31555	COG2169	Transcriptional regulator
RHEC894_RS31570	COG1137	ATPase activity
RHEC894_RS31595	COG1012	belongs to the aldehyde dehydrogenase family
RHEC894_RS31645	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RHEC894_RS31675	COG3938	Belongs to the proline racemase family
RHEC894_RS31680	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
RHEC894_RS31685	COG1802	Transcriptional regulator
RHEC894_RS31695	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
RHEC894_RS31705	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RHEC894_RS31710	COG2197	response regulator
RHEC894_RS31715	COG0840	transmembrane signaling receptor activity
RHEC894_RS31725	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RHEC894_RS31730	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
RHEC894_RS31735	COG1522	sequence-specific DNA binding
RHEC894_RS31780	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RHEC894_RS31790	COG1063	alcohol dehydrogenase
RHEC894_RS31795	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
RHEC894_RS31805	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
RHEC894_RS31815	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
RHEC894_RS31820	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
RHEC894_RS31840	COG0840	transmembrane signaling receptor activity
RHEC894_RS31855	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RHEC894_RS31875	COG0626	cystathionine gamma-synthase activity
RHEC894_RS31890	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
RHEC894_RS31925	COG4774	siderophore transport
RHEC894_RS31930	COG3706	GGDEF domain
RHEC894_RS31940	COG2885	chlorophyll binding
RHEC894_RS31960	COG0673	inositol 2-dehydrogenase activity
RHEC894_RS31985	COG1609	Transcriptional regulator
RHEC894_RS31995	COG0840	transmembrane signaling receptor activity
RHEC894_RS31995	COG2972	Histidine kinase
RHEC894_RS32005	COG1982	Orn Lys Arg decarboxylase major
RHEC894_RS32010	COG1247	-acetyltransferase
RHEC894_RS32025	COG0673	inositol 2-dehydrogenase activity
RHEC894_RS32035	COG1175	transmembrane transport
RHEC894_RS32040	COG0395	ABC-type sugar transport system, permease component
RHEC894_RS32045	COG1940	carbohydrate kinase activity
RHEC894_RS32055	COG3842	ATPase activity
RHEC894_RS32060	COG1192	Involved in chromosome partitioning
RHEC894_RS32065	COG1475	DNA binding
RHEC894_RS32070	COG1414	Transcriptional regulator