locus-tag	class	description
CHR56_RS00010	COG3750	Belongs to the UPF0335 family
CHR56_RS00125	COG1278	Cold shock
CHR56_RS00170	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CHR56_RS00185	COG0436	Aminotransferase
CHR56_RS00195	COG3243	poly(R)-hydroxyalkanoic acid synthase
CHR56_RS00205	COG0436	Aminotransferase
CHR56_RS00215	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CHR56_RS00220	COG0511	ligase activity, forming carbon-carbon bonds
CHR56_RS00230	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CHR56_RS00240	COG4765	Protein conserved in bacteria
CHR56_RS00260	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CHR56_RS00275	COG3811	Belongs to the UPF0386 family
CHR56_RS00285	COG0154	amidase activity
CHR56_RS00290	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CHR56_RS00295	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CHR56_RS00300	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CHR56_RS00315	COG0024	Methionine aminopeptidase
CHR56_RS00320	COG2003	Belongs to the UPF0758 family
CHR56_RS00335	COG1032	radical SAM domain protein
CHR56_RS00345	COG0544	peptidyl-prolyl cis-trans isomerase activity
CHR56_RS00375	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CHR56_RS00400	COG1862	Preprotein translocase
CHR56_RS00415	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CHR56_RS00420	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CHR56_RS00425	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CHR56_RS00430	COG0805	protein transport
CHR56_RS00435	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CHR56_RS00440	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CHR56_RS00445	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CHR56_RS00450	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CHR56_RS00455	COG1472	Belongs to the glycosyl hydrolase 3 family
CHR56_RS00465	COG0018	arginyl-trna synthetase
CHR56_RS00470	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CHR56_RS00475	COG0316	Belongs to the HesB IscA family
CHR56_RS00500	COG0525	valine-tRNA ligase activity
CHR56_RS00510	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CHR56_RS00565	COG0753	catalase activity
CHR56_RS00595	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CHR56_RS00605	COG1176	ABC-type spermidine putrescine transport system, permease component I
CHR56_RS00610	COG1177	transmembrane transport
CHR56_RS00615	COG3842	ATPase activity
CHR56_RS00640	COG0625	glutathione transferase activity
CHR56_RS00645	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CHR56_RS00650	COG0450	alkyl hydroperoxide reductase
CHR56_RS00660	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CHR56_RS00665	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CHR56_RS00665	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CHR56_RS00670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CHR56_RS00690	COG3707	response regulator
CHR56_RS00695	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CHR56_RS00705	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CHR56_RS00715	COG0243	molybdopterin cofactor binding
CHR56_RS00720	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CHR56_RS00735	COG0415	Belongs to the DNA photolyase family
CHR56_RS00750	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CHR56_RS00755	COG0300	oxidoreductase activity
CHR56_RS00760	COG3806	Anti-sigma factor
CHR56_RS00775	COG2897	thiosulfate sulfurtransferase activity
CHR56_RS00805	COG4221	oxidoreductase activity
CHR56_RS00815	COG0686	Belongs to the AlaDH PNT family
CHR56_RS00820	COG1522	sequence-specific DNA binding
CHR56_RS00840	COG0737	Belongs to the 5'-nucleotidase family
CHR56_RS00845	COG0583	DNA-binding transcription factor activity
CHR56_RS00850	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CHR56_RS00865	COG3706	GGDEF domain
CHR56_RS00875	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CHR56_RS00890	COG0655	NAD(P)H dehydrogenase (quinone) activity
CHR56_RS00895	COG1546	Belongs to the CinA family
CHR56_RS00895	COG1058	Belongs to the CinA family
CHR56_RS00905	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CHR56_RS00915	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CHR56_RS00960	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CHR56_RS01030	COG3119	arylsulfatase activity
CHR56_RS01035	COG0714	Associated with various cellular activities
CHR56_RS01055	COG2304	oxidoreductase activity
CHR56_RS01065	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CHR56_RS01075	COG0668	transmembrane transport
CHR56_RS01085	COG4566	intracellular signal transduction
CHR56_RS01095	COG0784	Response regulator, receiver
CHR56_RS01175	COG0071	Belongs to the small heat shock protein (HSP20) family
CHR56_RS01215	COG2197	response regulator
CHR56_RS01240	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CHR56_RS01330	COG0625	glutathione transferase activity
CHR56_RS01340	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CHR56_RS01350	COG1522	sequence-specific DNA binding
CHR56_RS01355	COG1522	sequence-specific DNA binding
CHR56_RS01405	COG2197	response regulator
CHR56_RS01435	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CHR56_RS01440	COG0673	inositol 2-dehydrogenase activity
CHR56_RS01455	COG3842	ATPase activity
CHR56_RS01460	COG0395	ABC-type sugar transport system, permease component
CHR56_RS01465	COG1175	transmembrane transport
CHR56_RS01470	COG1653	transport
CHR56_RS01475	COG1012	belongs to the aldehyde dehydrogenase family
CHR56_RS01480	COG1024	Enoyl-CoA hydratase
CHR56_RS01490	COG1609	Transcriptional regulator
CHR56_RS01500	COG1473	amidohydrolase
CHR56_RS01505	COG2271	Major facilitator Superfamily
CHR56_RS01515	COG5002	protein histidine kinase activity
CHR56_RS01530	COG0583	DNA-binding transcription factor activity
CHR56_RS01535	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS01540	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CHR56_RS01545	COG0596	Alpha beta hydrolase
CHR56_RS01550	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CHR56_RS01575	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CHR56_RS01595	COG0129	dihydroxy-acid dehydratase activity
CHR56_RS01600	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CHR56_RS01605	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CHR56_RS01615	COG2963	transposase activity
CHR56_RS01620	COG3436	PFAM IS66 Orf2 family protein
CHR56_RS01625	COG4372	Transposase
CHR56_RS01630	COG0203	ribosomal protein L17
CHR56_RS01635	COG0202	RNA polymerase activity
CHR56_RS01640	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CHR56_RS01645	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CHR56_RS01650	COG0563	adenylate kinase activity
CHR56_RS01660	COG0200	Binds to the 23S rRNA
CHR56_RS01665	COG1841	ribosomal large subunit assembly
CHR56_RS01670	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CHR56_RS01675	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CHR56_RS01680	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CHR56_RS01685	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CHR56_RS01690	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CHR56_RS01695	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CHR56_RS01700	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CHR56_RS01705	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CHR56_RS01710	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CHR56_RS01715	COG0255	Belongs to the universal ribosomal protein uL29 family
CHR56_RS01720	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CHR56_RS01725	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CHR56_RS01730	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CHR56_RS01735	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CHR56_RS01740	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CHR56_RS01745	COG0089	rRNA binding
CHR56_RS01750	COG0088	Forms part of the polypeptide exit tunnel
CHR56_RS01755	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CHR56_RS01760	COG0051	transcription antitermination factor activity, RNA binding
CHR56_RS01765	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CHR56_RS01770	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CHR56_RS01775	COG0049	tRNA binding
CHR56_RS01780	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CHR56_RS01790	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CHR56_RS01795	COG0085	RNA polymerase activity
CHR56_RS01800	COG0222	ribosome binding
CHR56_RS01805	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CHR56_RS01810	COG0081	regulation of translation
CHR56_RS01815	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CHR56_RS01825	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CHR56_RS01835	COG1086	Polysaccharide biosynthesis protein
CHR56_RS01840	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CHR56_RS01855	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CHR56_RS01870	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CHR56_RS01890	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CHR56_RS01895	COG0860	N-Acetylmuramoyl-L-alanine amidase
CHR56_RS01900	COG1530	ribonuclease E activity
CHR56_RS01910	COG1960	acyl-CoA dehydrogenase activity
CHR56_RS01915	COG0540	Belongs to the ATCase OTCase family
CHR56_RS01930	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CHR56_RS01935	COG0758	DNA mediated transformation
CHR56_RS01940	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CHR56_RS01945	COG0557	exoribonuclease II activity
CHR56_RS01955	COG0477	Major facilitator Superfamily
CHR56_RS01960	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CHR56_RS01970	COG0784	Response regulator, receiver
CHR56_RS01990	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CHR56_RS02010	COG1136	(ABC) transporter
CHR56_RS02020	COG0442	prolyl-tRNA aminoacylation
CHR56_RS02035	COG0346	lactoylglutathione lyase activity
CHR56_RS02045	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CHR56_RS02045	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CHR56_RS02050	COG1007	ATP synthesis coupled electron transport
CHR56_RS02075	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CHR56_RS02080	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CHR56_RS02090	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CHR56_RS02090	COG3743	rRNA binding
CHR56_RS02095	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CHR56_RS02100	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CHR56_RS02110	COG0649	NAD binding
CHR56_RS02115	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CHR56_RS02120	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CHR56_RS02125	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CHR56_RS02155	COG0386	Belongs to the glutathione peroxidase family
CHR56_RS02175	COG0667	Aldo Keto reductase
CHR56_RS02185	COG0697	spore germination
CHR56_RS02190	COG0776	regulation of translation
CHR56_RS02195	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CHR56_RS02200	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CHR56_RS02205	COG0740	serine-type endopeptidase activity
CHR56_RS02210	COG3706	GGDEF domain
CHR56_RS02215	COG2124	cytochrome p450
CHR56_RS02220	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CHR56_RS02225	COG5001	Diguanylate cyclase
CHR56_RS02255	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CHR56_RS02280	COG1832	CoA-binding protein
CHR56_RS02295	COG1024	Enoyl-CoA hydratase
CHR56_RS02310	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CHR56_RS02315	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CHR56_RS02325	COG0010	Belongs to the arginase family
CHR56_RS02330	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CHR56_RS02340	COG1612	heme a metabolic process
CHR56_RS02365	COG0297	glycogen (starch) synthase activity
CHR56_RS02380	COG0395	ABC-type sugar transport system, permease component
CHR56_RS02385	COG1175	transmembrane transport
CHR56_RS02395	COG0454	-acetyltransferase
CHR56_RS02395	COG0456	acetyltransferase
CHR56_RS02400	COG1940	carbohydrate kinase activity
CHR56_RS02430	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CHR56_RS02440	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CHR56_RS02450	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CHR56_RS02460	COG1215	transferase activity, transferring glycosyl groups
CHR56_RS02490	COG0776	regulation of translation
CHR56_RS02495	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CHR56_RS02500	COG0416	fatty acid biosynthetic process
CHR56_RS02530	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CHR56_RS02535	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CHR56_RS02540	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CHR56_RS02565	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CHR56_RS02565	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CHR56_RS02570	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CHR56_RS02575	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CHR56_RS02595	COG0113	porphobilinogen synthase activity
CHR56_RS02605	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CHR56_RS02615	COG2336	PFAM SpoVT AbrB
CHR56_RS02630	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CHR56_RS02640	COG1309	transcriptional regulator
CHR56_RS02650	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CHR56_RS02660	COG2132	Multicopper oxidase
CHR56_RS02665	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CHR56_RS02670	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CHR56_RS02685	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CHR56_RS02695	COG0628	permease
CHR56_RS02700	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CHR56_RS02705	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CHR56_RS02710	COG3454	Phosphonate metabolism
CHR56_RS02730	COG0243	molybdopterin cofactor binding
CHR56_RS02735	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CHR56_RS02750	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS02755	COG0322	excinuclease ABC activity
CHR56_RS02760	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CHR56_RS02770	COG0314	molybdopterin synthase activity
CHR56_RS02790	COG0105	UTP biosynthetic process
CHR56_RS02810	COG0488	(ABC) transporter
CHR56_RS02830	COG0765	amino acid transport
CHR56_RS02835	COG1126	abc transporter atp-binding protein
CHR56_RS02840	COG2079	MmgE PrpD family protein
CHR56_RS02845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CHR56_RS02850	COG1505	serine-type exopeptidase activity
CHR56_RS02870	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CHR56_RS02875	COG0671	phosphoesterase, PA-phosphatase related
CHR56_RS02890	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CHR56_RS02900	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CHR56_RS02905	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CHR56_RS02910	COG0194	GDP metabolic process
CHR56_RS02915	COG1561	YicC-like family, N-terminal region
CHR56_RS02920	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CHR56_RS02925	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CHR56_RS02930	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CHR56_RS02940	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CHR56_RS02950	COG0667	Aldo Keto reductase
CHR56_RS02955	COG0360	Binds together with S18 to 16S ribosomal RNA
CHR56_RS02960	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CHR56_RS02970	COG0359	binds to the 23S rRNA
CHR56_RS02975	COG0305	Participates in initiation and elongation during chromosome replication
CHR56_RS02995	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CHR56_RS03000	COG1280	lysine exporter protein (LysE YggA)
CHR56_RS03010	COG1286	toxin biosynthetic process
CHR56_RS03015	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CHR56_RS03020	COG4221	oxidoreductase activity
CHR56_RS03030	COG0215	cysteine-tRNA ligase activity
CHR56_RS03055	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CHR56_RS03080	COG5265	(ABC) transporter
CHR56_RS03085	COG0688	phosphatidylethanolamine metabolic process
CHR56_RS03090	COG1183	phosphatidylcholine synthase activity
CHR56_RS03100	COG1742	UPF0060 membrane protein
CHR56_RS03105	COG1051	belongs to the nudix hydrolase family
CHR56_RS03125	COG0354	folic acid binding
CHR56_RS03130	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CHR56_RS03140	COG0668	transmembrane transport
CHR56_RS03145	COG2032	superoxide dismutase activity
CHR56_RS03155	COG3300	MHYT domain
CHR56_RS03155	COG5001	Diguanylate cyclase
CHR56_RS03160	COG1418	mRNA catabolic process
CHR56_RS03170	COG0656	L-ascorbic acid biosynthetic process
CHR56_RS03175	COG1381	Involved in DNA repair and RecF pathway recombination
CHR56_RS03185	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CHR56_RS03190	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CHR56_RS03195	COG0571	ribonuclease III activity
CHR56_RS03200	COG0681	Belongs to the peptidase S26 family
CHR56_RS03205	COG0736	holo-[acyl-carrier-protein] synthase activity
CHR56_RS03225	COG1758	RNA polymerase activity
CHR56_RS03235	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CHR56_RS03240	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CHR56_RS03305	COG0673	inositol 2-dehydrogenase activity
CHR56_RS03315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CHR56_RS03320	COG3962	Belongs to the TPP enzyme family
CHR56_RS03330	COG3718	enzyme involved in inositol metabolism
CHR56_RS03385	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CHR56_RS03405	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CHR56_RS03415	COG3795	YCII-related domain
CHR56_RS03420	COG3795	YCII-related domain
CHR56_RS03430	COG4941	Belongs to the sigma-70 factor family
CHR56_RS03440	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CHR56_RS03445	COG0463	Glycosyl transferase, family 2
CHR56_RS03450	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CHR56_RS03455	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CHR56_RS03480	COG2255	four-way junction helicase activity
CHR56_RS03530	COG4964	Belongs to the GSP D family
CHR56_RS03550	COG0174	glutamine synthetase
CHR56_RS03560	COG2814	Major facilitator Superfamily
CHR56_RS03565	COG1733	regulation of RNA biosynthetic process
CHR56_RS03575	COG2239	Acts as a magnesium transporter
CHR56_RS03590	COG1376	ErfK ybiS ycfS ynhG family protein
CHR56_RS03620	COG0443	Heat shock 70 kDa protein
CHR56_RS03650	COG3290	protein histidine kinase activity
CHR56_RS03650	COG0840	transmembrane signaling receptor activity
CHR56_RS03655	COG0308	aminopeptidase N
CHR56_RS03660	COG2205	protein histidine kinase activity
CHR56_RS03660	COG2202	Pas domain
CHR56_RS03670	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CHR56_RS03675	COG2205	protein histidine kinase activity
CHR56_RS03680	COG0745	RESPONSE REGULATOR receiver
CHR56_RS03685	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CHR56_RS03700	COG3088	subunit of a heme lyase
CHR56_RS03705	COG1138	Cytochrome C-type biogenesis protein
CHR56_RS03715	COG4235	cytochrome complex assembly
CHR56_RS03755	COG1309	transcriptional regulator
CHR56_RS03770	COG0625	glutathione transferase activity
CHR56_RS03785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CHR56_RS03790	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CHR56_RS03795	COG1609	Transcriptional regulator
CHR56_RS03800	COG1082	Xylose isomerase domain protein TIM barrel
CHR56_RS03810	COG0673	inositol 2-dehydrogenase activity
CHR56_RS03820	COG0459	protein refolding
CHR56_RS03825	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CHR56_RS03860	COG0583	DNA-binding transcription factor activity
CHR56_RS03885	COG3239	Fatty acid desaturase
CHR56_RS03890	COG4221	oxidoreductase activity
CHR56_RS03900	COG2983	Belongs to the UPF0260 family
CHR56_RS03905	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CHR56_RS03945	COG2207	Transcriptional regulator
CHR56_RS03955	COG2205	protein histidine kinase activity
CHR56_RS03965	COG2166	iron-sulfur cluster assembly
CHR56_RS03970	COG4957	zinc ion binding
CHR56_RS03975	COG1320	monovalent cation:proton antiporter activity
CHR56_RS03980	COG2212	antiporter activity
CHR56_RS03985	COG1863	multisubunit Na H antiporter MnhE subunit
CHR56_RS03990	COG0651	ATP synthesis coupled electron transport
CHR56_RS03995	COG1006	Multisubunit Na H antiporter MnhC subunit
CHR56_RS04000	COG2111	Na H antiporter
CHR56_RS04005	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CHR56_RS04005	COG2111	Na H antiporter
CHR56_RS04015	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CHR56_RS04030	COG1247	-acetyltransferase
CHR56_RS04035	COG1272	protein, Hemolysin III
CHR56_RS04045	COG2514	catechol 2,3-dioxygenase activity
CHR56_RS04095	COG0477	Major facilitator Superfamily
CHR56_RS04100	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CHR56_RS04105	COG4993	Dehydrogenase
CHR56_RS04140	COG2010	Cytochrome c
CHR56_RS04150	COG1280	lysine exporter protein (LysE YggA)
CHR56_RS04165	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CHR56_RS04180	COG0730	response to heat
CHR56_RS04190	COG2814	Major facilitator Superfamily
CHR56_RS04200	COG0625	glutathione transferase activity
CHR56_RS04225	COG0583	DNA-binding transcription factor activity
CHR56_RS04235	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CHR56_RS04240	COG1064	alcohol dehydrogenase
CHR56_RS04265	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CHR56_RS04285	COG0840	transmembrane signaling receptor activity
CHR56_RS04290	COG1253	flavin adenine dinucleotide binding
CHR56_RS04295	COG4106	trans-aconitate 2-methyltransferase activity
CHR56_RS04300	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CHR56_RS04310	COG1051	belongs to the nudix hydrolase family
CHR56_RS04315	COG3609	addiction module antidote protein, CC2985 family
CHR56_RS04330	COG0433	COG0433 Predicted ATPase
CHR56_RS04335	COG0488	(ABC) transporter
CHR56_RS04345	COG0488	(ABC) transporter
CHR56_RS04370	COG1764	response to oxidative stress
CHR56_RS04375	COG1846	Transcriptional regulator
CHR56_RS04385	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CHR56_RS04395	COG1278	Cold shock
CHR56_RS04400	COG1376	ErfK ybiS ycfS ynhG family protein
CHR56_RS04405	COG1376	ErfK ybiS ycfS ynhG family protein
CHR56_RS04415	COG1793	dna ligase
CHR56_RS04425	COG0596	Alpha beta hydrolase
CHR56_RS04430	COG0584	glycerophosphoryl diester phosphodiesterase
CHR56_RS04455	COG0435	Glutathione S-transferase
CHR56_RS04460	COG0583	DNA-binding transcription factor activity
CHR56_RS04520	COG2226	methyltransferase
CHR56_RS04525	COG0604	alcohol dehydrogenase
CHR56_RS04525	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS04525	COG3321	synthase
CHR56_RS04530	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CHR56_RS04545	COG1309	transcriptional regulator
CHR56_RS04550	COG1012	belongs to the aldehyde dehydrogenase family
CHR56_RS04555	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CHR56_RS04580	COG1959	2 iron, 2 sulfur cluster binding
CHR56_RS04585	COG0175	sulfate reduction
CHR56_RS04590	COG0175	sulfate reduction
CHR56_RS04595	COG2895	sulfate adenylyltransferase (ATP) activity
CHR56_RS04660	COG0438	transferase activity, transferring glycosyl groups
CHR56_RS04680	COG0583	DNA-binding transcription factor activity
CHR56_RS04690	COG0583	DNA-binding transcription factor activity
CHR56_RS04695	COG1609	Transcriptional regulator
CHR56_RS04780	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CHR56_RS04810	COG0823	Involved in the tonB-independent uptake of proteins
CHR56_RS04810	COG1506	peptidase
CHR56_RS04825	COG0640	Transcriptional regulator
CHR56_RS04845	COG1902	pentaerythritol trinitrate reductase activity
CHR56_RS04885	COG3384	dioxygenase
CHR56_RS04900	COG4191	Histidine kinase
CHR56_RS04900	COG0784	Response regulator, receiver
CHR56_RS04910	COG0235	Class ii aldolase
CHR56_RS04925	COG0590	tRNA wobble adenosine to inosine editing
CHR56_RS04940	COG1309	transcriptional regulator
CHR56_RS04950	COG0300	oxidoreductase activity
CHR56_RS05005	COG3385	transposase activity
CHR56_RS05010	COG0640	Transcriptional regulator
CHR56_RS05020	COG0625	glutathione transferase activity
CHR56_RS05050	COG0702	epimerase
CHR56_RS05065	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS05070	COG0640	Transcriptional regulator
CHR56_RS05095	COG0583	DNA-binding transcription factor activity
CHR56_RS05100	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS05105	COG0259	pyridoxamine-phosphate oxidase activity
CHR56_RS05145	COG3119	arylsulfatase activity
CHR56_RS05155	COG0251	oxidation-reduction process
CHR56_RS05180	COG1917	Cupin 2, conserved barrel domain protein
CHR56_RS05180	COG2207	Transcriptional regulator
CHR56_RS05185	COG2863	cytochrome
CHR56_RS05200	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CHR56_RS05205	COG2226	methyltransferase
CHR56_RS05215	COG0740	serine-type endopeptidase activity
CHR56_RS05225	COG0640	Transcriptional regulator
CHR56_RS05240	COG0583	DNA-binding transcription factor activity
CHR56_RS05255	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CHR56_RS05280	COG1309	transcriptional regulator
CHR56_RS05290	COG3415	Transposase
CHR56_RS05295	COG3385	transposase activity
CHR56_RS05310	COG3119	arylsulfatase activity
CHR56_RS05335	COG3385	transposase activity
CHR56_RS05440	COG0285	dihydrofolate synthase activity
CHR56_RS05560	COG0574	Belongs to the PEP-utilizing enzyme family
CHR56_RS05560	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CHR56_RS05570	COG1196	nuclear chromosome segregation
CHR56_RS05595	COG1194	a g-specific adenine glycosylase
CHR56_RS05610	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CHR56_RS05640	COG2972	Histidine kinase
CHR56_RS05640	COG0840	transmembrane signaling receptor activity
CHR56_RS05645	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CHR56_RS05665	COG0612	Peptidase, M16
CHR56_RS05690	COG1960	acyl-CoA dehydrogenase activity
CHR56_RS05750	COG0803	Belongs to the bacterial solute-binding protein 9 family
CHR56_RS05755	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CHR56_RS05760	COG1121	(ABC) transporter
CHR56_RS05780	COG0765	amino acid transport
CHR56_RS05785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHR56_RS05790	COG1126	abc transporter atp-binding protein
CHR56_RS05795	COG2072	flavoprotein involved in K transport
CHR56_RS05820	COG0300	oxidoreductase activity
CHR56_RS05835	COG4221	oxidoreductase activity
CHR56_RS05850	COG0667	Aldo Keto reductase
CHR56_RS05860	COG1902	pentaerythritol trinitrate reductase activity
CHR56_RS05880	COG3485	protocatechuate 3,4-dioxygenase
CHR56_RS05900	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS05905	COG2814	Major facilitator Superfamily
CHR56_RS05910	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CHR56_RS05915	COG0678	peroxiredoxin activity
CHR56_RS05915	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CHR56_RS05925	COG1678	Uncharacterized ACR, COG1678
CHR56_RS05945	COG0328	RNA-DNA hybrid ribonuclease activity
CHR56_RS05950	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CHR56_RS05955	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CHR56_RS05960	COG3346	SURF1 family
CHR56_RS05980	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
CHR56_RS05990	COG0109	protoheme IX farnesyltransferase activity
CHR56_RS05995	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CHR56_RS06000	COG1565	acr, cog1565
CHR56_RS06000	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CHR56_RS06010	COG0312	modulator of DNA gyrase
CHR56_RS06025	COG1686	Belongs to the peptidase S11 family
CHR56_RS06035	COG0259	pyridoxamine-phosphate oxidase activity
CHR56_RS06045	COG0484	heat shock protein binding
CHR56_RS06050	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CHR56_RS06070	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CHR56_RS06075	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CHR56_RS06075	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CHR56_RS06080	COG3214	Protein conserved in bacteria
CHR56_RS06085	COG1122	ATPase activity
CHR56_RS06090	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CHR56_RS06095	COG1268	BioY protein
CHR56_RS06105	COG0596	Alpha beta hydrolase
CHR56_RS06165	COG0123	including yeast histone deacetylase and acetoin utilization protein
CHR56_RS06170	COG1722	exodeoxyribonuclease VII activity
CHR56_RS06180	COG1741	Belongs to the pirin family
CHR56_RS06185	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CHR56_RS06190	COG0840	transmembrane signaling receptor activity
CHR56_RS06205	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CHR56_RS06220	COG1960	acyl-CoA dehydrogenase activity
CHR56_RS06235	COG4638	Rieske (2fe-2S)
CHR56_RS06250	COG0009	L-threonylcarbamoyladenylate synthase
CHR56_RS06270	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CHR56_RS06285	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CHR56_RS06290	COG2183	response to ionizing radiation
CHR56_RS06295	COG0751	glycine-tRNA ligase activity
CHR56_RS06300	COG1683	Conserved Protein
CHR56_RS06305	COG0840	transmembrane signaling receptor activity
CHR56_RS06310	COG0840	transmembrane signaling receptor activity
CHR56_RS06320	COG0151	Belongs to the GarS family
CHR56_RS06330	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CHR56_RS06335	COG1704	LemA family
CHR56_RS06340	COG0752	glycyl-tRNA synthetase alpha subunit
CHR56_RS06355	COG1914	H( )-stimulated, divalent metal cation uptake system
CHR56_RS06370	COG0142	geranyltranstransferase activity
CHR56_RS06380	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CHR56_RS06385	COG0521	Mo-molybdopterin cofactor biosynthetic process
CHR56_RS06405	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CHR56_RS06410	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CHR56_RS06415	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CHR56_RS06425	COG0356	it plays a direct role in the translocation of protons across the membrane
CHR56_RS06440	COG3158	transport of potassium into the cell
CHR56_RS06445	COG0598	Magnesium transport protein CorA
CHR56_RS06455	COG0489	protein tyrosine kinase activity
CHR56_RS06460	COG2197	response regulator
CHR56_RS06465	COG1414	Transcriptional regulator
CHR56_RS06470	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS06475	COG3734	2-keto-3-deoxy-galactonokinase
CHR56_RS06480	COG0800	Aldolase
CHR56_RS06485	COG3386	PFAM SMP-30 Gluconolaconase
CHR56_RS06495	COG5001	Diguanylate cyclase
CHR56_RS06495	COG3300	MHYT domain
CHR56_RS06500	COG0745	RESPONSE REGULATOR receiver
CHR56_RS06505	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CHR56_RS06525	COG1172	Belongs to the binding-protein-dependent transport system permease family
CHR56_RS06535	COG1663	tetraacyldisaccharide 4'-kinase activity
CHR56_RS06545	COG1519	Transferase
CHR56_RS06555	COG0483	inositol monophosphate 1-phosphatase activity
CHR56_RS06560	COG0312	modulator of DNA gyrase
CHR56_RS06585	COG0742	ribosomal rna small subunit methyltransferase
CHR56_RS06590	COG1187	pseudouridine synthase activity
CHR56_RS06595	COG0590	tRNA wobble adenosine to inosine editing
CHR56_RS06610	COG0196	riboflavin kinase activity
CHR56_RS06620	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CHR56_RS06635	COG0625	glutathione transferase activity
CHR56_RS06640	COG2259	Doxx family
CHR56_RS06645	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CHR56_RS06650	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CHR56_RS06655	COG0124	histidyl-tRNA synthetase
CHR56_RS06675	COG0667	Aldo Keto reductase
CHR56_RS06690	COG2818	Glycosylase
CHR56_RS06695	COG1376	ErfK ybiS ycfS ynhG family protein
CHR56_RS06700	COG1376	ErfK ybiS ycfS ynhG family protein
CHR56_RS06700	COG1388	LysM domain
CHR56_RS06715	COG0247	lactate metabolic process
CHR56_RS06720	COG0277	FAD linked oxidase domain protein
CHR56_RS06725	COG0277	FAD linked oxidase domain protein
CHR56_RS06730	COG0583	DNA-binding transcription factor activity
CHR56_RS06740	COG4221	oxidoreductase activity
CHR56_RS06740	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CHR56_RS06740	COG3321	synthase
CHR56_RS06740	COG0604	alcohol dehydrogenase
CHR56_RS06745	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CHR56_RS06760	COG0306	phosphate transporter
CHR56_RS06785	COG0583	DNA-binding transcription factor activity
CHR56_RS06800	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS06805	COG0583	DNA-binding transcription factor activity
CHR56_RS06825	COG1234	tRNA 3'-trailer cleavage
CHR56_RS06830	COG0477	Major facilitator Superfamily
CHR56_RS06845	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CHR56_RS06905	COG2226	methyltransferase
CHR56_RS06910	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CHR56_RS06925	COG4372	Transposase
CHR56_RS06930	COG3436	PFAM IS66 Orf2 family protein
CHR56_RS06935	COG2963	transposase activity
CHR56_RS06940	COG2963	transposase activity
CHR56_RS06950	COG4372	Transposase
CHR56_RS06965	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CHR56_RS06990	COG4106	trans-aconitate 2-methyltransferase activity
CHR56_RS07000	COG0463	Glycosyl transferase, family 2
CHR56_RS07050	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
CHR56_RS07055	COG1088	dTDP-glucose 4,6-dehydratase activity
CHR56_RS07060	COG1091	dTDP-4-dehydrorhamnose reductase activity
CHR56_RS07065	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CHR56_RS07090	COG1755	Isoprenylcysteine carboxyl methyltransferase
CHR56_RS07095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CHR56_RS07100	COG3265	gluconokinase activity
CHR56_RS07105	COG4608	Belongs to the ABC transporter superfamily
CHR56_RS07110	COG0444	Belongs to the ABC transporter superfamily
CHR56_RS07115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHR56_RS07120	COG0601	transmembrane transport
CHR56_RS07125	COG0747	negative chemotaxis
CHR56_RS07130	COG1959	2 iron, 2 sulfur cluster binding
CHR56_RS07190	COG2205	protein histidine kinase activity
CHR56_RS07195	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CHR56_RS07205	COG1177	transmembrane transport
CHR56_RS07210	COG1176	ABC-type spermidine putrescine transport system, permease component I
CHR56_RS07215	COG3842	ATPase activity
CHR56_RS07230	COG2224	Isocitrate lyase
CHR56_RS07250	COG0840	transmembrane signaling receptor activity
CHR56_RS07255	COG2972	Histidine kinase
CHR56_RS07255	COG0840	transmembrane signaling receptor activity
CHR56_RS07260	COG2081	HI0933 family
CHR56_RS07270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CHR56_RS07275	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CHR56_RS07280	COG0363	glucosamine-6-phosphate deaminase activity
CHR56_RS07285	COG0129	dihydroxy-acid dehydratase activity
CHR56_RS07295	COG3842	ATPase activity
CHR56_RS07300	COG0366	Alpha amylase catalytic
CHR56_RS07305	COG0395	ABC-type sugar transport system, permease component
CHR56_RS07310	COG1175	transmembrane transport
CHR56_RS07315	COG1653	transport
CHR56_RS07320	COG1609	Transcriptional regulator
CHR56_RS07335	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CHR56_RS07360	COG1684	flagellar biosynthetic protein fliR
CHR56_RS07365	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CHR56_RS07370	COG4794	Type iii secretion
CHR56_RS07380	COG5443	negative regulation of bacterial-type flagellum assembly
CHR56_RS07400	COG1749	Flagellar hook protein flgE
CHR56_RS07425	COG1360	Flagellar Motor Protein
CHR56_RS07435	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CHR56_RS07460	COG1338	Plays a role in the flagellum-specific transport system
CHR56_RS07470	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CHR56_RS07480	COG1706	bacterial-type flagellum-dependent cell motility
CHR56_RS07485	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
CHR56_RS07490	COG4786	Flagellar basal body rod
CHR56_RS07495	COG1677	Flagellar hook-basal body complex protein FliE
CHR56_RS07500	COG1558	bacterial-type flagellum-dependent cell motility
CHR56_RS07505	COG1815	bacterial-type flagellum-dependent cell motility
CHR56_RS07515	COG1157	protein secretion by the type III secretion system
CHR56_RS07520	COG4786	Flagellar basal body rod
CHR56_RS07525	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CHR56_RS07530	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CHR56_RS07535	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CHR56_RS07540	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CHR56_RS07545	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CHR56_RS07560	COG2771	luxR family
CHR56_RS07565	COG1766	The M ring may be actively involved in energy transduction
CHR56_RS07575	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CHR56_RS07580	COG0745	RESPONSE REGULATOR receiver
CHR56_RS07585	COG2201	protein-glutamate methylesterase activity
CHR56_RS07590	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CHR56_RS07595	COG0835	chemotaxis
CHR56_RS07600	COG0643	Histidine kinase
CHR56_RS07600	COG2198	Histidine kinase
CHR56_RS07605	COG0745	RESPONSE REGULATOR receiver
CHR56_RS07615	COG0840	transmembrane signaling receptor activity
CHR56_RS07620	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CHR56_RS07630	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CHR56_RS07630	COG4651	solute:proton antiporter activity
CHR56_RS07655	COG2197	response regulator
CHR56_RS07665	COG4251	negative regulation of phosphorylation
CHR56_RS07675	COG4251	negative regulation of phosphorylation
CHR56_RS07680	COG0346	lactoylglutathione lyase activity
CHR56_RS07710	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CHR56_RS07715	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CHR56_RS07750	COG0596	Alpha beta hydrolase
CHR56_RS07775	COG2144	transferase activity, transferring acyl groups
CHR56_RS07780	COG0438	transferase activity, transferring glycosyl groups
CHR56_RS07790	COG2072	flavoprotein involved in K transport
CHR56_RS07800	COG1609	Transcriptional regulator
CHR56_RS07825	COG0673	inositol 2-dehydrogenase activity
CHR56_RS07835	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS07845	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
CHR56_RS07850	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CHR56_RS07855	COG1940	carbohydrate kinase activity
CHR56_RS07860	COG1082	Xylose isomerase domain protein TIM barrel
CHR56_RS07870	COG1175	transmembrane transport
CHR56_RS07875	COG0395	ABC-type sugar transport system, permease component
CHR56_RS07885	COG3842	ATPase activity
CHR56_RS07890	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS07910	COG1250	3-hydroxyacyl-CoA dehydrogenase
CHR56_RS07915	COG1960	acyl-CoA dehydrogenase activity
CHR56_RS07920	COG0583	DNA-binding transcription factor activity
CHR56_RS07925	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CHR56_RS07930	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CHR56_RS07940	COG0431	NADPH-dependent FMN reductase
CHR56_RS07945	COG1063	alcohol dehydrogenase
CHR56_RS07950	COG0683	leucine binding
CHR56_RS07960	COG0148	phosphopyruvate hydratase activity
CHR56_RS07985	COG1609	Transcriptional regulator
CHR56_RS07995	COG0179	Fumarylacetoacetate (FAA) hydrolase
CHR56_RS08040	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CHR56_RS08045	COG0424	maF-like protein
CHR56_RS08050	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CHR56_RS08055	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CHR56_RS08060	COG5328	Belongs to the UPF0262 family
CHR56_RS08065	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CHR56_RS08075	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CHR56_RS08120	COG5001	Diguanylate cyclase
CHR56_RS08130	COG0436	Aminotransferase
CHR56_RS08135	COG1970	mechanosensitive ion channel activity
CHR56_RS08140	COG2205	protein histidine kinase activity
CHR56_RS08140	COG2198	Histidine kinase
CHR56_RS08140	COG0784	Response regulator, receiver
CHR56_RS08170	COG1278	Cold shock
CHR56_RS08180	COG1024	Enoyl-CoA hydratase
CHR56_RS08180	COG1250	3-hydroxyacyl-CoA dehydrogenase
CHR56_RS08190	COG0183	Belongs to the thiolase family
CHR56_RS08195	COG1960	acyl-CoA dehydrogenase activity
CHR56_RS08225	COG0730	response to heat
CHR56_RS08250	COG1201	RNA secondary structure unwinding
CHR56_RS08260	COG1959	2 iron, 2 sulfur cluster binding
CHR56_RS08265	COG3547	Transposase (IS116 IS110 IS902 family)
CHR56_RS08270	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CHR56_RS08295	COG0534	Mate efflux family protein
CHR56_RS08300	COG0167	dihydroorotate dehydrogenase activity
CHR56_RS08335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHR56_RS08340	COG0840	transmembrane signaling receptor activity
CHR56_RS08360	COG0717	Belongs to the dCTP deaminase family
CHR56_RS08370	COG2967	ApaG domain
CHR56_RS08375	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CHR56_RS08380	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CHR56_RS08385	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CHR56_RS08395	COG0745	RESPONSE REGULATOR receiver
CHR56_RS08400	COG0704	Plays a role in the regulation of phosphate uptake
CHR56_RS08405	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CHR56_RS08415	COG0573	inorganic phosphate transmembrane transporter activity
CHR56_RS08420	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CHR56_RS08425	COG5002	protein histidine kinase activity
CHR56_RS08430	COG2326	polyphosphate kinase activity
CHR56_RS08455	COG3278	Belongs to the heme-copper respiratory oxidase family
CHR56_RS08470	COG2010	Cytochrome c
CHR56_RS08505	COG0477	Major facilitator Superfamily
CHR56_RS08520	COG2226	methyltransferase
CHR56_RS08540	COG4178	(ABC) transporter
CHR56_RS08560	COG2721	sulfolactate sulfo-lyase activity
CHR56_RS08585	COG1172	Belongs to the binding-protein-dependent transport system permease family
CHR56_RS08590	COG1063	alcohol dehydrogenase
CHR56_RS08600	COG3385	transposase activity
CHR56_RS08605	COG3142	Participates in the control of copper homeostasis
CHR56_RS08610	COG0583	DNA-binding transcription factor activity
CHR56_RS08620	COG1732	Glycine betaine
CHR56_RS08625	COG1174	glycine betaine transport
CHR56_RS08630	COG1125	glycine betaine transport
CHR56_RS08635	COG1174	glycine betaine transport
CHR56_RS08645	COG3250	beta-galactosidase activity
CHR56_RS08655	COG0318	PFAM AMP-dependent synthetase and ligase
CHR56_RS08660	COG0166	Belongs to the GPI family
CHR56_RS08670	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CHR56_RS08675	COG1309	transcriptional regulator
CHR56_RS08690	COG0625	glutathione transferase activity
CHR56_RS08705	COG0418	dihydroorotase activity
CHR56_RS08710	COG1072	(Pantothenic acid kinase))
CHR56_RS08730	COG1940	carbohydrate kinase activity
CHR56_RS08760	COG3300	MHYT domain
CHR56_RS08760	COG5001	Diguanylate cyclase
CHR56_RS08765	COG1309	transcriptional regulator
CHR56_RS08780	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS08785	COG1309	transcriptional regulator
CHR56_RS08790	COG3938	Belongs to the proline racemase family
CHR56_RS08795	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS08800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CHR56_RS08815	COG0667	Aldo Keto reductase
CHR56_RS08820	COG1309	transcriptional regulator
CHR56_RS08825	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CHR56_RS08835	COG0604	alcohol dehydrogenase
CHR56_RS08875	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CHR56_RS08920	COG0840	transmembrane signaling receptor activity
CHR56_RS08925	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CHR56_RS08930	COG0594	ribonuclease P activity
CHR56_RS08935	COG0706	membrane insertase activity
CHR56_RS08940	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CHR56_RS08945	COG1278	Cold shock
CHR56_RS08960	COG3920	Histidine kinase
CHR56_RS08965	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CHR56_RS08975	COG5484	DNA packaging
CHR56_RS08980	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CHR56_RS08985	COG1304	FMN binding
CHR56_RS08995	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CHR56_RS08995	COG2169	Transcriptional regulator
CHR56_RS09020	COG2171	N-acyltransferase activity
CHR56_RS09025	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CHR56_RS09035	COG0101	tRNA pseudouridine synthase activity
CHR56_RS09040	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CHR56_RS09055	COG0242	peptide deformylase activity
CHR56_RS09070	COG0840	transmembrane signaling receptor activity
CHR56_RS09080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CHR56_RS09085	COG0840	transmembrane signaling receptor activity
CHR56_RS09090	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHR56_RS09095	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CHR56_RS09110	COG1137	ATPase activity
CHR56_RS09115	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CHR56_RS09125	COG0616	signal peptide processing
CHR56_RS09125	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CHR56_RS09130	COG0776	regulation of translation
CHR56_RS09155	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CHR56_RS09155	COG0116	Belongs to the methyltransferase superfamily
CHR56_RS09160	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CHR56_RS09165	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CHR56_RS09185	COG0280	phosphate acetyltransferase
CHR56_RS09185	COG0281	malic enzyme
CHR56_RS09190	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CHR56_RS09220	COG0180	Tryptophanyl-tRNA synthetase
CHR56_RS09230	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CHR56_RS09255	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CHR56_RS09260	COG1702	phosphate starvation-inducible protein PhoH
CHR56_RS09265	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CHR56_RS09270	COG4535	Mg2 and Co2 transporter CorC
CHR56_RS09275	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CHR56_RS09280	COG1396	sequence-specific DNA binding
CHR56_RS09285	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CHR56_RS09290	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CHR56_RS09310	COG0071	Belongs to the small heat shock protein (HSP20) family
CHR56_RS09320	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CHR56_RS09325	COG1420	regulation of RNA biosynthetic process
CHR56_RS09330	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CHR56_RS09340	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CHR56_RS09345	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CHR56_RS09355	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CHR56_RS09360	COG0268	Binds directly to 16S ribosomal RNA
CHR56_RS09365	COG1024	Enoyl-CoA hydratase
CHR56_RS09370	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CHR56_RS09375	COG2226	methyltransferase
CHR56_RS09380	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CHR56_RS09385	COG2986	histidine ammonia-lyase
CHR56_RS09390	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CHR56_RS09410	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CHR56_RS09420	COG2814	Major facilitator Superfamily
CHR56_RS09430	COG0583	DNA-binding transcription factor activity
CHR56_RS09440	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS09445	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CHR56_RS09460	COG2807	transmembrane transport
CHR56_RS09490	COG0583	DNA-binding transcription factor activity
CHR56_RS09495	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CHR56_RS09500	COG0756	dUTP diphosphatase activity
CHR56_RS09510	COG1522	sequence-specific DNA binding
CHR56_RS09515	COG0697	spore germination
CHR56_RS09520	COG0783	Belongs to the Dps family
CHR56_RS09540	COG0606	chelatase, subunit chli
CHR56_RS09545	COG0189	ligase activity
CHR56_RS09550	COG1172	Belongs to the binding-protein-dependent transport system permease family
CHR56_RS09565	COG1609	Transcriptional regulator
CHR56_RS09575	COG0792	nuclease activity
CHR56_RS09580	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CHR56_RS09595	COG3963	phosphatidate phosphatase activity
CHR56_RS09605	COG0284	orotidine-5'-phosphate decarboxylase activity
CHR56_RS09625	COG1968	undecaprenyl-diphosphatase activity
CHR56_RS09635	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CHR56_RS09645	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CHR56_RS09650	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CHR56_RS09650	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CHR56_RS09690	COG0519	Catalyzes the synthesis of GMP from XMP
CHR56_RS09690	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CHR56_RS09700	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS09705	COG0583	DNA-binding transcription factor activity
CHR56_RS09710	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CHR56_RS09725	COG1881	PFAM PEBP family protein
CHR56_RS09730	COG2207	Transcriptional regulator
CHR56_RS09745	COG0583	DNA-binding transcription factor activity
CHR56_RS09755	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS09760	COG4221	oxidoreductase activity
CHR56_RS09765	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CHR56_RS09775	COG1393	Belongs to the ArsC family
CHR56_RS09795	COG2309	aminopeptidase activity
CHR56_RS09800	COG2249	NAD(P)H dehydrogenase (quinone) activity
CHR56_RS09805	COG1570	exodeoxyribonuclease VII activity
CHR56_RS09850	COG3685	Protein conserved in bacteria
CHR56_RS09860	COG0667	Aldo Keto reductase
CHR56_RS09870	COG0072	phenylalanine-tRNA ligase activity
CHR56_RS09870	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CHR56_RS09875	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CHR56_RS09880	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CHR56_RS09885	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CHR56_RS09895	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CHR56_RS09900	COG0596	Alpha beta hydrolase
CHR56_RS09900	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CHR56_RS09925	COG2137	regulation of response to DNA damage stimulus
CHR56_RS09955	COG0481	GTPase activity
CHR56_RS09980	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CHR56_RS10020	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CHR56_RS10030	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CHR56_RS10040	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CHR56_RS10060	COG0747	negative chemotaxis
CHR56_RS10070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHR56_RS10075	COG0154	amidase activity
CHR56_RS10090	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CHR56_RS10100	COG1280	lysine exporter protein (LysE YggA)
CHR56_RS10130	COG4964	Belongs to the GSP D family
CHR56_RS10165	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CHR56_RS10170	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CHR56_RS10175	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CHR56_RS10185	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CHR56_RS10190	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CHR56_RS10195	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CHR56_RS10205	COG1079	Belongs to the binding-protein-dependent transport system permease family
CHR56_RS10210	COG4603	Belongs to the binding-protein-dependent transport system permease family
CHR56_RS10215	COG3845	ABC transporter
CHR56_RS10220	COG1744	ABC transporter substrate-binding protein PnrA-like
CHR56_RS10235	COG1522	sequence-specific DNA binding
CHR56_RS10255	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CHR56_RS10270	COG4172	Belongs to the ABC transporter superfamily
CHR56_RS10275	COG4239	(ABC) transporter, permease
CHR56_RS10280	COG4174	ABC transporter (Permease)
CHR56_RS10285	COG4166	transmembrane transport
CHR56_RS10290	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
CHR56_RS10295	COG1803	Methylglyoxal synthase
CHR56_RS10300	COG0837	glucose binding
CHR56_RS10305	COG1132	(ABC) transporter
CHR56_RS10310	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CHR56_RS10315	COG0588	phosphoglycerate mutase activity
CHR56_RS10320	COG2188	Transcriptional regulator
CHR56_RS10325	COG3624	Phosphonate C-P lyase system protein PhnG
CHR56_RS10330	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CHR56_RS10335	COG3626	phosphonate metabolism
CHR56_RS10340	COG3627	carbon phosphorus lyase activity
CHR56_RS10345	COG4107	phosphonate C-P lyase system protein PhnK
CHR56_RS10350	COG4778	phosphonate C-P lyase system protein PhnL
CHR56_RS10360	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CHR56_RS10370	COG3639	organic phosphonate transmembrane transporter activity
CHR56_RS10375	COG3639	organic phosphonate transmembrane transporter activity
CHR56_RS10380	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CHR56_RS10385	COG3454	Phosphonate metabolism
CHR56_RS10390	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CHR56_RS10395	COG0456	acetyltransferase
CHR56_RS10395	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CHR56_RS10400	COG1674	ftsk spoiiie
CHR56_RS10405	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CHR56_RS10405	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CHR56_RS10420	COG3300	MHYT domain
CHR56_RS10420	COG5001	Diguanylate cyclase
CHR56_RS10425	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CHR56_RS10440	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CHR56_RS10445	COG0443	Heat shock 70 kDa protein
CHR56_RS10450	COG0484	heat shock protein binding
CHR56_RS10460	COG1396	sequence-specific DNA binding
CHR56_RS10465	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CHR56_RS10490	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CHR56_RS10495	COG0679	Auxin Efflux Carrier
CHR56_RS10500	COG3474	cytochrome
CHR56_RS10505	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CHR56_RS10510	COG1605	Chorismate mutase
CHR56_RS10510	COG0077	Prephenate dehydratase
CHR56_RS10525	COG2378	regulation of single-species biofilm formation
CHR56_RS10530	COG2816	NAD+ diphosphatase activity
CHR56_RS10545	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CHR56_RS10550	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CHR56_RS10555	COG2258	MOSC domain
CHR56_RS10560	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CHR56_RS10565	COG2951	lytic endotransglycosylase activity
CHR56_RS10575	COG2814	Major facilitator Superfamily
CHR56_RS10580	COG0779	Required for maturation of 30S ribosomal subunits
CHR56_RS10595	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CHR56_RS10600	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CHR56_RS10605	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CHR56_RS10610	COG2267	carboxylic ester hydrolase activity
CHR56_RS10615	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CHR56_RS10620	COG1185	polyribonucleotide nucleotidyltransferase activity
CHR56_RS10625	COG2813	Specifically methylates the guanine in position
CHR56_RS10630	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CHR56_RS10640	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CHR56_RS10695	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CHR56_RS10700	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CHR56_RS10705	COG0539	negative regulation of cytoplasmic translation
CHR56_RS10725	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CHR56_RS10730	COG1012	belongs to the aldehyde dehydrogenase family
CHR56_RS10735	COG2900	Belongs to the SlyX family
CHR56_RS10745	COG1904	glucuronate isomerase
CHR56_RS10750	COG0246	Mannitol dehydrogenase
CHR56_RS10765	COG3842	ATPase activity
CHR56_RS10770	COG0673	inositol 2-dehydrogenase activity
CHR56_RS10775	COG0395	ABC-type sugar transport system, permease component
CHR56_RS10780	COG1175	transmembrane transport
CHR56_RS10790	COG1309	transcriptional regulator
CHR56_RS10795	COG0673	inositol 2-dehydrogenase activity
CHR56_RS10810	COG0673	inositol 2-dehydrogenase activity
CHR56_RS10815	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CHR56_RS10830	COG2182	Extracellular solute-binding protein
CHR56_RS10845	COG1215	transferase activity, transferring glycosyl groups
CHR56_RS10850	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CHR56_RS10865	COG2197	response regulator
CHR56_RS10950	COG2423	ornithine cyclodeaminase activity
CHR56_RS10955	COG1643	Atp-dependent helicase
CHR56_RS10965	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CHR56_RS10985	COG2124	cytochrome p450
CHR56_RS10995	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CHR56_RS11005	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CHR56_RS11010	COG0131	Imidazoleglycerol-phosphate dehydratase
CHR56_RS11020	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CHR56_RS11035	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CHR56_RS11040	COG0107	imidazoleglycerol-phosphate synthase activity
CHR56_RS11045	COG0140	phosphoribosyl-ATP diphosphatase activity
CHR56_RS11050	COG1072	(Pantothenic acid kinase))
CHR56_RS11065	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CHR56_RS11070	COG0745	RESPONSE REGULATOR receiver
CHR56_RS11075	COG0642	Histidine kinase
CHR56_RS11085	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHR56_RS11085	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CHR56_RS11090	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHR56_RS11095	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CHR56_RS11100	COG2205	protein histidine kinase activity
CHR56_RS11105	COG3178	'Phosphotransferase
CHR56_RS11110	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CHR56_RS11115	COG2887	Belongs to the helicase family. UvrD subfamily
CHR56_RS11120	COG1074	ATP-dependent DNA helicase activity
CHR56_RS11130	COG0285	dihydrofolate synthase activity
CHR56_RS11135	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CHR56_RS11140	COG0159	tryptophan synthase activity
CHR56_RS11145	COG0133	tryptophan synthase activity
CHR56_RS11150	COG0135	phosphoribosylanthranilate isomerase activity
CHR56_RS11175	COG0435	Glutathione S-transferase
CHR56_RS11205	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CHR56_RS11215	COG3030	protein affecting phage T7 exclusion by the F plasmid
CHR56_RS11220	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CHR56_RS11225	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CHR56_RS11230	COG0237	dephospho-CoA kinase activity
CHR56_RS11235	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CHR56_RS11240	COG0424	maF-like protein
CHR56_RS11245	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CHR56_RS11255	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CHR56_RS11260	COG1981	membrane
CHR56_RS11265	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CHR56_RS11270	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CHR56_RS11275	COG0445	tRNA wobble uridine modification
CHR56_RS11280	COG0357	Ribosomal RNA small subunit methyltransferase G
CHR56_RS11305	COG0495	leucyl-tRNA aminoacylation
CHR56_RS11310	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CHR56_RS11330	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CHR56_RS11340	COG0501	Belongs to the peptidase M48B family
CHR56_RS11355	COG0138	bifunctional purine biosynthesis protein purh
CHR56_RS11365	COG2270	Major facilitator Superfamily
CHR56_RS11370	COG2902	Dehydrogenase
CHR56_RS11385	COG0288	reversible hydration of carbon dioxide
CHR56_RS11390	COG5001	Diguanylate cyclase
CHR56_RS11390	COG4251	negative regulation of phosphorylation
CHR56_RS11390	COG2203	Gaf domain
CHR56_RS11390	COG3706	GGDEF domain
CHR56_RS11400	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CHR56_RS11410	COG1785	Belongs to the alkaline phosphatase family
CHR56_RS11420	COG1136	(ABC) transporter
CHR56_RS11440	COG0671	phosphoesterase, PA-phosphatase related
CHR56_RS11445	COG0473	3-isopropylmalate dehydrogenase activity
CHR56_RS11455	COG0066	3-isopropylmalate dehydratase activity
CHR56_RS11490	COG0587	DNA-directed DNA polymerase activity
CHR56_RS11505	COG0494	nUDIX hydrolase
CHR56_RS11515	COG0793	Belongs to the peptidase S41A family
CHR56_RS11525	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CHR56_RS11530	COG0799	negative regulation of ribosome biogenesis
CHR56_RS11540	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CHR56_RS11545	COG4149	molybdate abc transporter
CHR56_RS11550	COG0725	ABC transporter, periplasmic molybdate-binding protein
CHR56_RS11555	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CHR56_RS11560	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CHR56_RS11565	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CHR56_RS11570	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CHR56_RS11590	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CHR56_RS11595	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CHR56_RS11650	COG1129	ABC transporter
CHR56_RS11655	COG4211	Belongs to the binding-protein-dependent transport system permease family
CHR56_RS11670	COG0601	transmembrane transport
CHR56_RS11675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHR56_RS11680	COG0444	Belongs to the ABC transporter superfamily
CHR56_RS11685	COG4608	Belongs to the ABC transporter superfamily
CHR56_RS11695	COG3459	Glycosyltransferase 36 associated
CHR56_RS11725	COG1132	(ABC) transporter
CHR56_RS11735	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CHR56_RS11740	COG0431	NADPH-dependent FMN reductase
CHR56_RS11750	COG1126	abc transporter atp-binding protein
CHR56_RS11755	COG0765	amino acid transport
CHR56_RS11760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHR56_RS11765	COG0697	spore germination
CHR56_RS11775	COG2223	nitrite transmembrane transporter activity
CHR56_RS11780	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CHR56_RS11805	COG0142	geranyltranstransferase activity
CHR56_RS11810	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CHR56_RS11825	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CHR56_RS11835	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
CHR56_RS11840	COG0183	Belongs to the thiolase family
CHR56_RS11845	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS11870	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CHR56_RS11875	COG1329	Transcriptional regulator
CHR56_RS11880	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CHR56_RS11905	COG0488	(ABC) transporter
CHR56_RS11915	COG4178	(ABC) transporter
CHR56_RS11920	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CHR56_RS11930	COG2188	Transcriptional regulator
CHR56_RS11935	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CHR56_RS11940	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CHR56_RS11945	COG4821	SIS domain
CHR56_RS11950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CHR56_RS11955	COG1126	abc transporter atp-binding protein
CHR56_RS11960	COG0765	amino acid transport
CHR56_RS11975	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CHR56_RS11990	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CHR56_RS12000	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CHR56_RS12025	COG0438	transferase activity, transferring glycosyl groups
CHR56_RS12040	COG5383	Protein conserved in bacteria
CHR56_RS12045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CHR56_RS12050	COG1012	belongs to the aldehyde dehydrogenase family
CHR56_RS12065	COG3842	ATPase activity
CHR56_RS12075	COG4172	Belongs to the ABC transporter superfamily
CHR56_RS12085	COG0405	Gamma-glutamyltransferase
CHR56_RS12090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHR56_RS12095	COG0601	transmembrane transport
CHR56_RS12100	COG4166	transmembrane transport
CHR56_RS12155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CHR56_RS12170	COG0583	DNA-binding transcription factor activity
CHR56_RS12175	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS12185	COG0582	viral genome integration into host DNA
CHR56_RS12220	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CHR56_RS12270	COG3118	belongs to the thioredoxin family
CHR56_RS12280	COG2835	tetraacyldisaccharide 4'-kinase activity
CHR56_RS12285	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CHR56_RS12290	COG1946	Acyl-CoA thioesterase
CHR56_RS12295	COG0347	Belongs to the P(II) protein family
CHR56_RS12300	COG0004	ammonium transporteR
CHR56_RS12305	COG1674	ftsk spoiiie
CHR56_RS12310	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CHR56_RS12325	COG0745	RESPONSE REGULATOR receiver
CHR56_RS12345	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CHR56_RS12355	COG0765	amino acid transport
CHR56_RS12360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHR56_RS12365	COG0335	large ribosomal subunit rRNA binding
CHR56_RS12370	COG0336	Belongs to the RNA methyltransferase TrmD family
CHR56_RS12375	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CHR56_RS12380	COG0228	four-way junction DNA binding
CHR56_RS12385	COG1605	Chorismate mutase
CHR56_RS12385	COG0287	Prephenate dehydrogenase
CHR56_RS12390	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CHR56_RS12405	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CHR56_RS12410	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CHR56_RS12415	COG0552	protein localization to endoplasmic reticulum
CHR56_RS12420	COG2917	probably involved in intracellular septation
CHR56_RS12440	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CHR56_RS12445	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CHR56_RS12450	COG4133	protoheme IX ABC transporter activity
CHR56_RS12455	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CHR56_RS12475	COG0670	Belongs to the BI1 family
CHR56_RS12485	COG4181	ATPase activity
CHR56_RS12495	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CHR56_RS12500	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CHR56_RS12505	COG2154	pterin-4-alpha-carbinolamine dehydratase
CHR56_RS12515	COG1595	DNA-templated transcription, initiation
CHR56_RS12525	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CHR56_RS12535	COG4120	Belongs to the binding-protein-dependent transport system permease family
CHR56_RS12555	COG0137	argininosuccinate synthase activity
CHR56_RS12560	COG1012	belongs to the aldehyde dehydrogenase family
CHR56_RS12565	COG4221	oxidoreductase activity
CHR56_RS12615	COG0339	signal peptide processing
CHR56_RS12620	COG1217	gtp-binding protein TYPA
CHR56_RS12630	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CHR56_RS12635	COG1872	DUF167
CHR56_RS12650	COG0519	Catalyzes the synthesis of GMP from XMP
CHR56_RS12650	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CHR56_RS12675	COG0181	hydroxymethylbilane synthase activity
CHR56_RS12680	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CHR56_RS12685	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CHR56_RS12725	COG1126	abc transporter atp-binding protein
CHR56_RS12735	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CHR56_RS12740	COG0765	amino acid transport
CHR56_RS12750	COG2186	Transcriptional regulator
CHR56_RS12770	COG2986	histidine ammonia-lyase
CHR56_RS12795	COG0601	transmembrane transport
CHR56_RS12805	COG0747	negative chemotaxis
CHR56_RS12825	COG2423	ornithine cyclodeaminase activity
CHR56_RS12830	COG0765	amino acid transport
CHR56_RS12835	COG0765	amino acid transport
CHR56_RS12840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHR56_RS12860	COG4149	molybdate abc transporter
CHR56_RS12865	COG3842	ATPase activity
CHR56_RS12910	COG2845	Protein of unknown function (DUF459)
CHR56_RS12915	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CHR56_RS12920	COG0039	L-malate dehydrogenase activity
CHR56_RS12925	COG0045	succinate-CoA ligase (ADP-forming) activity
CHR56_RS12935	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CHR56_RS12950	COG0508	dehydrogenase complex catalyzes the overall conversion of
CHR56_RS12965	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS12970	COG1280	lysine exporter protein (LysE YggA)
CHR56_RS12990	COG3038	cytochrome b561
CHR56_RS13005	COG4974	Belongs to the 'phage' integrase family
CHR56_RS13020	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CHR56_RS13030	COG0129	dihydroxy-acid dehydratase activity
CHR56_RS13035	COG0673	inositol 2-dehydrogenase activity
CHR56_RS13045	COG3664	PFAM glycoside hydrolase family 39
CHR56_RS13055	COG0601	transmembrane transport
CHR56_RS13060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHR56_RS13065	COG0444	Belongs to the ABC transporter superfamily
CHR56_RS13070	COG4608	Belongs to the ABC transporter superfamily
CHR56_RS13085	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CHR56_RS13090	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CHR56_RS13095	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CHR56_RS13100	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CHR56_RS13110	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CHR56_RS13125	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CHR56_RS13130	COG1116	anion transmembrane transporter activity
CHR56_RS13135	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CHR56_RS13155	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS13160	COG0640	Transcriptional regulator
CHR56_RS13165	COG0583	DNA-binding transcription factor activity
CHR56_RS13180	COG3383	formate dehydrogenase (NAD+) activity
CHR56_RS13185	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CHR56_RS13200	COG0835	chemotaxis
CHR56_RS13210	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CHR56_RS13215	COG0010	Belongs to the arginase family
CHR56_RS13230	COG0729	surface antigen
CHR56_RS13240	COG0156	8-amino-7-oxononanoate synthase activity
CHR56_RS13255	COG1175	transmembrane transport
CHR56_RS13260	COG0395	ABC-type sugar transport system, permease component
CHR56_RS13275	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CHR56_RS13305	COG0531	amino acid
CHR56_RS13310	COG4302	ethanolamine ammonia-lyase activity
CHR56_RS13315	COG4303	Ethanolamine ammonia lyase large subunit
CHR56_RS13330	COG1686	Belongs to the peptidase S11 family
CHR56_RS13335	COG0523	cobalamin synthesis protein
CHR56_RS13345	COG3034	peptidoglycan biosynthetic process
CHR56_RS13350	COG0825	malonyl-CoA metabolic process
CHR56_RS13355	COG4974	Belongs to the 'phage' integrase family
CHR56_RS13365	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CHR56_RS13370	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CHR56_RS13375	COG4536	flavin adenine dinucleotide binding
CHR56_RS13405	COG0563	adenylate kinase activity
CHR56_RS13415	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CHR56_RS13435	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CHR56_RS13440	COG2226	methyltransferase
CHR56_RS13445	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CHR56_RS13450	COG0287	Prephenate dehydrogenase
CHR56_RS13465	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CHR56_RS13485	COG2884	Cell division ATP-binding protein ftsE
CHR56_RS13520	COG0165	Argininosuccinate lyase
CHR56_RS13525	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CHR56_RS13530	COG1250	3-hydroxyacyl-CoA dehydrogenase
CHR56_RS13535	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CHR56_RS13540	COG2086	electron transfer activity
CHR56_RS13565	COG0300	oxidoreductase activity
CHR56_RS13575	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CHR56_RS13605	COG4651	solute:proton antiporter activity
CHR56_RS13605	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CHR56_RS13645	COG0667	Aldo Keto reductase
CHR56_RS13650	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CHR56_RS13665	COG0653	protein targeting
CHR56_RS13670	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CHR56_RS13680	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CHR56_RS13685	COG0456	acetyltransferase
CHR56_RS13690	COG0494	nUDIX hydrolase
CHR56_RS13705	COG2226	methyltransferase
CHR56_RS13720	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CHR56_RS13730	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CHR56_RS13735	COG0527	aspartate kinase activity
CHR56_RS13745	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CHR56_RS13750	COG2890	protein-(glutamine-N5) methyltransferase activity
CHR56_RS13760	COG0542	response to heat
CHR56_RS13800	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CHR56_RS13805	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CHR56_RS13830	COG0649	NAD binding
CHR56_RS13835	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CHR56_RS13840	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CHR56_RS13860	COG0651	ATP synthesis coupled electron transport
CHR56_RS13870	COG0651	ATP synthesis coupled electron transport
CHR56_RS13875	COG0713	ATP synthesis coupled electron transport
CHR56_RS13890	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CHR56_RS13900	COG3459	Glycosyltransferase 36 associated
CHR56_RS13905	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CHR56_RS13910	COG0516	GMP reductase activity
CHR56_RS13910	COG0517	IMP dehydrogenase activity
CHR56_RS13915	COG4178	(ABC) transporter
CHR56_RS13920	COG0840	transmembrane signaling receptor activity
CHR56_RS13920	COG2972	Histidine kinase
CHR56_RS13945	COG0387	Pfam Sodium calcium exchanger
CHR56_RS13950	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS13960	COG0693	protein deglycase activity
CHR56_RS13970	COG1012	belongs to the aldehyde dehydrogenase family
CHR56_RS13980	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CHR56_RS13985	COG0493	'glutamate synthase
CHR56_RS13985	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CHR56_RS14000	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CHR56_RS14005	COG1780	Probably involved in ribonucleotide reductase function
CHR56_RS14015	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CHR56_RS14025	COG0602	queuosine metabolic process
CHR56_RS14030	COG0720	synthase
CHR56_RS14035	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CHR56_RS14040	COG1609	Transcriptional regulator
CHR56_RS14045	COG1653	transport
CHR56_RS14050	COG1175	transmembrane transport
CHR56_RS14055	COG0395	ABC-type sugar transport system, permease component
CHR56_RS14060	COG3842	ATPase activity
CHR56_RS14070	COG1609	Transcriptional regulator
CHR56_RS14080	COG1653	transport
CHR56_RS14085	COG1175	transmembrane transport
CHR56_RS14090	COG0395	ABC-type sugar transport system, permease component
CHR56_RS14105	COG3386	PFAM SMP-30 Gluconolaconase
CHR56_RS14115	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS14130	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CHR56_RS14135	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS14145	COG4948	Mandelate Racemase Muconate Lactonizing
CHR56_RS14150	COG2186	Transcriptional regulator
CHR56_RS14160	COG1129	ABC transporter
CHR56_RS14175	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS14180	COG1764	response to oxidative stress
CHR56_RS14205	COG1940	carbohydrate kinase activity
CHR56_RS14275	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CHR56_RS14295	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CHR56_RS14310	COG1595	DNA-templated transcription, initiation
CHR56_RS14365	COG1177	transmembrane transport
CHR56_RS14370	COG1176	ABC-type spermidine putrescine transport system, permease component I
CHR56_RS14375	COG3842	ATPase activity
CHR56_RS14380	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CHR56_RS14385	COG0583	DNA-binding transcription factor activity
CHR56_RS14395	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CHR56_RS14400	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CHR56_RS14405	COG1253	flavin adenine dinucleotide binding
CHR56_RS14430	COG1609	Transcriptional regulator
CHR56_RS14435	COG1070	Carbohydrate kinase
CHR56_RS14440	COG2115	Belongs to the xylose isomerase family
CHR56_RS14445	COG1609	Transcriptional regulator
CHR56_RS14450	COG1129	ABC transporter
CHR56_RS14455	COG1172	Belongs to the binding-protein-dependent transport system permease family
CHR56_RS14460	COG1879	ABC-type sugar transport system periplasmic component
CHR56_RS14470	COG0673	inositol 2-dehydrogenase activity
CHR56_RS14490	COG1054	Belongs to the UPF0176 family
CHR56_RS14505	COG2954	triphosphatase activity
CHR56_RS14510	COG0800	Aldolase
CHR56_RS14540	COG0583	DNA-binding transcription factor activity
CHR56_RS14560	COG3706	GGDEF domain
CHR56_RS14580	COG0523	cobalamin synthesis protein
CHR56_RS14590	COG1846	Transcriptional regulator
CHR56_RS14595	COG1609	Transcriptional regulator
CHR56_RS14600	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CHR56_RS14605	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CHR56_RS14610	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CHR56_RS14620	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CHR56_RS14625	COG5001	Diguanylate cyclase
CHR56_RS14660	COG3920	Histidine kinase
CHR56_RS14660	COG2202	Pas domain
CHR56_RS14670	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CHR56_RS14690	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CHR56_RS14705	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CHR56_RS14705	COG0446	pyridine nucleotide-disulphide oxidoreductase
CHR56_RS14725	COG1523	belongs to the glycosyl hydrolase 13 family
CHR56_RS14730	COG0033	Phosphoglucomutase
CHR56_RS14735	COG0297	glycogen (starch) synthase activity
CHR56_RS14740	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CHR56_RS14745	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CHR56_RS14750	COG0058	SHG alpha-glucan phosphorylase activity
CHR56_RS14765	COG2307	Protein conserved in bacteria
CHR56_RS14765	COG2308	Evidence 4 Homologs of previously reported genes of
CHR56_RS14790	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CHR56_RS14890	COG0071	Belongs to the small heat shock protein (HSP20) family
CHR56_RS14910	COG0067	glutamate synthase
CHR56_RS14910	COG0069	glutamate synthase activity
CHR56_RS14910	COG0070	glutamate synthase
CHR56_RS14930	COG2951	lytic endotransglycosylase activity
CHR56_RS14935	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CHR56_RS14955	COG0330	HflC and HflK could
CHR56_RS14960	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CHR56_RS14965	COG0737	Belongs to the 5'-nucleotidase family
CHR56_RS14980	COG5310	Homospermidine synthase
CHR56_RS15010	COG2204	response regulator
CHR56_RS15015	COG3108	Peptidase M15
CHR56_RS15020	COG3750	Belongs to the UPF0335 family
CHR56_RS15040	COG0469	pyruvate kinase activity
CHR56_RS15045	COG1280	lysine exporter protein (LysE YggA)
CHR56_RS15060	COG1942	4-Oxalocrotonate Tautomerase
CHR56_RS15065	COG0583	DNA-binding transcription factor activity
CHR56_RS15080	COG4221	oxidoreductase activity
CHR56_RS15100	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS15110	COG0457	Tetratricopeptide repeat
CHR56_RS15115	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CHR56_RS15120	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CHR56_RS15125	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CHR56_RS15140	COG0640	Transcriptional regulator
CHR56_RS15175	COG0643	Histidine kinase
CHR56_RS15175	COG2198	Histidine kinase
CHR56_RS15180	COG0835	chemotaxis
CHR56_RS15185	COG0840	transmembrane signaling receptor activity
CHR56_RS15190	COG0840	transmembrane signaling receptor activity
CHR56_RS15200	COG0835	chemotaxis
CHR56_RS15210	COG2201	protein-glutamate methylesterase activity
CHR56_RS15215	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS15220	COG1309	transcriptional regulator
CHR56_RS15225	COG0483	inositol monophosphate 1-phosphatase activity
CHR56_RS15250	COG3422	double-strand break repair
CHR56_RS15265	COG1132	(ABC) transporter
CHR56_RS15270	COG0254	rRNA binding
CHR56_RS15295	COG0384	phenazine biosynthesis protein PhzF
CHR56_RS15300	COG3588	fructose-bisphosphate aldolase
CHR56_RS15305	COG0126	phosphoglycerate kinase activity
CHR56_RS15375	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CHR56_RS15380	COG0668	transmembrane transport
CHR56_RS15390	COG0392	lysyltransferase activity
CHR56_RS15390	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CHR56_RS15405	COG0494	nUDIX hydrolase
CHR56_RS15410	COG1408	metallophosphoesterase
CHR56_RS15415	COG2255	four-way junction helicase activity
CHR56_RS15430	COG0632	four-way junction helicase activity
CHR56_RS15435	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CHR56_RS15440	COG0840	transmembrane signaling receptor activity
CHR56_RS15445	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CHR56_RS15450	COG0217	transcriptional regulatory protein
CHR56_RS15465	COG1692	metallophosphoesterase
CHR56_RS15480	COG1090	epimerase
CHR56_RS15495	COG0824	Thioesterase
CHR56_RS15505	COG0848	biopolymer transport protein
CHR56_RS15515	COG0823	Involved in the tonB-independent uptake of proteins
CHR56_RS15520	COG2885	chlorophyll binding
CHR56_RS15530	COG0037	tRNA processing
CHR56_RS15535	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CHR56_RS15540	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CHR56_RS15760	COG1783	phage Terminase large subunit
CHR56_RS15925	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CHR56_RS15935	COG5001	Diguanylate cyclase
CHR56_RS15940	COG0482	sulfurtransferase activity
CHR56_RS15965	COG0559	Belongs to the binding-protein-dependent transport system permease family
CHR56_RS15975	COG0683	leucine binding
CHR56_RS15995	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CHR56_RS16000	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CHR56_RS16005	COG0306	phosphate transporter
CHR56_RS16010	COG5001	Diguanylate cyclase
CHR56_RS16010	COG3300	MHYT domain
CHR56_RS16035	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CHR56_RS16070	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CHR56_RS16090	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CHR56_RS16095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CHR56_RS16100	COG1309	transcriptional regulator
CHR56_RS16105	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CHR56_RS16110	COG0471	metal ion transport
CHR56_RS16110	COG3273	potassium ion transport
CHR56_RS16170	COG1172	Belongs to the binding-protein-dependent transport system permease family
CHR56_RS16175	COG1129	ABC transporter
CHR56_RS16180	COG0702	epimerase
CHR56_RS16190	COG2186	Transcriptional regulator
CHR56_RS16195	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS16220	COG1376	ErfK ybiS ycfS ynhG family protein
CHR56_RS16225	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS16230	COG4993	Dehydrogenase
CHR56_RS16250	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CHR56_RS16285	COG1596	polysaccharide export
CHR56_RS16295	COG0489	protein tyrosine kinase activity
CHR56_RS16315	COG0438	transferase activity, transferring glycosyl groups
CHR56_RS16320	COG2244	polysaccharide biosynthetic process
CHR56_RS16355	COG1653	transport
CHR56_RS16360	COG1940	carbohydrate kinase activity
CHR56_RS16360	COG1846	Transcriptional regulator
CHR56_RS16365	COG1653	transport
CHR56_RS16370	COG1175	transmembrane transport
CHR56_RS16375	COG0395	ABC-type sugar transport system, permease component
CHR56_RS16380	COG3842	ATPase activity
CHR56_RS16395	COG3622	Belongs to the hyi family
CHR56_RS16400	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS16405	COG1959	2 iron, 2 sulfur cluster binding
CHR56_RS16415	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CHR56_RS16425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CHR56_RS16450	COG2094	Belongs to the DNA glycosylase MPG family
CHR56_RS16465	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS16470	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS16480	COG0657	acetylesterase activity
CHR56_RS16495	COG2084	Dehydrogenase
CHR56_RS16500	COG0129	dihydroxy-acid dehydratase activity
CHR56_RS16520	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CHR56_RS16530	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CHR56_RS16535	COG0564	pseudouridine synthase activity
CHR56_RS16620	COG0559	Belongs to the binding-protein-dependent transport system permease family
CHR56_RS16645	COG0683	leucine binding
CHR56_RS16660	COG2205	protein histidine kinase activity
CHR56_RS16660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHR56_RS16685	COG0411	ABC transporter
CHR56_RS16705	COG3813	Protein conserved in bacteria
CHR56_RS16710	COG0832	Belongs to the urease beta subunit family
CHR56_RS16715	COG3755	Protein conserved in bacteria
CHR56_RS16720	COG1442	glycosyl transferase family 8
CHR56_RS16725	COG0804	urea catabolic process
CHR56_RS16735	COG3706	GGDEF domain
CHR56_RS16750	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CHR56_RS16770	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CHR56_RS16775	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CHR56_RS16780	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CHR56_RS16810	COG1309	transcriptional regulator
CHR56_RS16815	COG4251	negative regulation of phosphorylation
CHR56_RS16825	COG0583	DNA-binding transcription factor activity
CHR56_RS16840	COG4977	sequence-specific DNA binding
CHR56_RS16850	COG0493	'glutamate synthase
CHR56_RS16860	COG0784	Response regulator, receiver
CHR56_RS16885	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CHR56_RS16890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CHR56_RS16895	COG4558	Periplasmic binding protein
CHR56_RS16955	COG2076	Multidrug Resistance protein
CHR56_RS16965	COG0673	inositol 2-dehydrogenase activity
CHR56_RS16985	COG0842	Transport permease protein
CHR56_RS16990	COG0842	Transport permease protein
CHR56_RS16995	COG1131	(ABC) transporter
CHR56_RS17000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CHR56_RS17005	COG1309	transcriptional regulator
CHR56_RS17020	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CHR56_RS17035	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CHR56_RS17035	COG0662	Cupin 2, conserved barrel domain protein
CHR56_RS17040	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CHR56_RS17045	COG0346	lactoylglutathione lyase activity
CHR56_RS17050	COG0400	carboxylic ester hydrolase activity
CHR56_RS17065	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CHR56_RS17070	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CHR56_RS17095	COG3206	protein involved in exopolysaccharide biosynthesis
CHR56_RS17095	COG0489	protein tyrosine kinase activity
CHR56_RS17115	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
CHR56_RS17120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CHR56_RS17145	COG1215	transferase activity, transferring glycosyl groups
CHR56_RS17150	COG0463	Glycosyl transferase, family 2
CHR56_RS17200	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CHR56_RS17205	COG1396	sequence-specific DNA binding
CHR56_RS17240	COG1215	transferase activity, transferring glycosyl groups
CHR56_RS17245	COG1132	(ABC) transporter
CHR56_RS17250	COG1442	glycosyl transferase family 8
CHR56_RS17250	COG1216	Glycosyl transferase, family 2
CHR56_RS17265	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CHR56_RS17275	COG3108	Peptidase M15
CHR56_RS17295	COG1129	ABC transporter
CHR56_RS17300	COG4214	carbohydrate transport
CHR56_RS17305	COG4213	ABC transporter substrate-binding protein
CHR56_RS17315	COG0673	inositol 2-dehydrogenase activity
CHR56_RS17345	COG4214	carbohydrate transport
CHR56_RS17360	COG0129	dihydroxy-acid dehydratase activity
CHR56_RS17375	COG2308	Evidence 4 Homologs of previously reported genes of
CHR56_RS17385	COG0513	Belongs to the DEAD box helicase family
CHR56_RS17390	COG4335	DNA alkylation repair
CHR56_RS17400	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CHR56_RS17405	COG0477	Major facilitator Superfamily
CHR56_RS17415	COG2205	protein histidine kinase activity
CHR56_RS17415	COG0784	Response regulator, receiver
CHR56_RS17415	COG5002	protein histidine kinase activity
CHR56_RS17420	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CHR56_RS17420	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CHR56_RS17425	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CHR56_RS17440	COG3648	Uricase
CHR56_RS17440	COG3195	allantoin biosynthetic process
CHR56_RS17450	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
CHR56_RS17455	COG2351	hydroxyisourate hydrolase activity
CHR56_RS17465	COG2268	Band 7 protein
CHR56_RS17480	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CHR56_RS17485	COG2267	carboxylic ester hydrolase activity
CHR56_RS17490	COG2453	phosphatase
CHR56_RS17490	COG0671	phosphoesterase, PA-phosphatase related
CHR56_RS17510	COG0402	S-adenosylhomocysteine deaminase activity
CHR56_RS17525	COG0583	DNA-binding transcription factor activity
CHR56_RS17540	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CHR56_RS17550	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS17555	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CHR56_RS17560	COG3795	YCII-related domain
CHR56_RS17565	COG4941	Belongs to the sigma-70 factor family
CHR56_RS17580	COG0024	Methionine aminopeptidase
CHR56_RS17595	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CHR56_RS17615	COG1160	GTP binding
CHR56_RS17620	COG1846	Transcriptional regulator
CHR56_RS17635	COG0174	glutamine synthetase
CHR56_RS17645	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CHR56_RS17655	COG4608	Belongs to the ABC transporter superfamily
CHR56_RS17665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHR56_RS17670	COG0601	transmembrane transport
CHR56_RS17680	COG0366	Alpha amylase catalytic
CHR56_RS17685	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CHR56_RS17700	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CHR56_RS17715	COG4175	Glycine betaine
CHR56_RS17730	COG1435	thymidine kinase activity
CHR56_RS17750	COG2197	response regulator
CHR56_RS17760	COG2862	Uncharacterized protein family, UPF0114
CHR56_RS17765	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CHR56_RS17780	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CHR56_RS17795	COG4771	TonB-dependent receptor
CHR56_RS17795	COG1629	transport
CHR56_RS17800	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CHR56_RS17800	COG0512	Glutamine amidotransferase of anthranilate synthase
CHR56_RS17820	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CHR56_RS17825	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CHR56_RS17830	COG3416	Protein conserved in bacteria
CHR56_RS17835	COG0740	serine-type endopeptidase activity
CHR56_RS17840	COG3135	benzoate transporter
CHR56_RS17845	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CHR56_RS17855	COG1733	regulation of RNA biosynthetic process
CHR56_RS17890	COG0435	Glutathione S-transferase
CHR56_RS17900	COG0454	-acetyltransferase
CHR56_RS17920	COG0714	Associated with various cellular activities
CHR56_RS17935	COG0617	tRNA 3'-terminal CCA addition
CHR56_RS17950	COG0408	coproporphyrinogen oxidase activity
CHR56_RS17965	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CHR56_RS17970	COG1132	(ABC) transporter
CHR56_RS17980	COG1132	(ABC) transporter
CHR56_RS18000	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CHR56_RS18000	COG2857	Cytochrome c1
CHR56_RS18005	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CHR56_RS18030	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CHR56_RS18040	COG0193	aminoacyl-tRNA hydrolase activity
CHR56_RS18050	COG5001	Diguanylate cyclase
CHR56_RS18050	COG3300	MHYT domain
CHR56_RS18055	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CHR56_RS18065	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CHR56_RS18090	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CHR56_RS18110	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CHR56_RS18115	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CHR56_RS18130	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CHR56_RS18135	COG1846	Transcriptional regulator
CHR56_RS18140	COG0745	RESPONSE REGULATOR receiver
CHR56_RS18150	COG1733	regulation of RNA biosynthetic process
CHR56_RS18165	COG1278	Cold shock
CHR56_RS18180	COG2133	pyrroloquinoline quinone binding
CHR56_RS18200	COG1442	glycosyl transferase family 8
CHR56_RS18210	COG0387	Pfam Sodium calcium exchanger
CHR56_RS18220	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CHR56_RS18220	COG0456	acetyltransferase
CHR56_RS18225	COG0583	DNA-binding transcription factor activity
CHR56_RS18240	COG1902	pentaerythritol trinitrate reductase activity
CHR56_RS18245	COG2814	Major facilitator Superfamily
CHR56_RS18255	COG0583	DNA-binding transcription factor activity
CHR56_RS18260	COG0492	ferredoxin-NADP+ reductase activity
CHR56_RS18265	COG1522	sequence-specific DNA binding
CHR56_RS18270	COG2204	response regulator
CHR56_RS18275	COG4191	Histidine kinase
CHR56_RS18280	COG1301	dicarboxylic acid transport
CHR56_RS18300	COG1573	uracil-dna glycosylase
CHR56_RS18305	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CHR56_RS18325	COG2321	neutral zinc metallopeptidase
CHR56_RS18330	COG0667	Aldo Keto reductase
CHR56_RS18335	COG0583	DNA-binding transcription factor activity
CHR56_RS18345	COG0534	Mate efflux family protein
CHR56_RS18355	COG0505	Belongs to the CarA family
CHR56_RS18375	COG0358	DNA primase activity
CHR56_RS18380	COG0514	ATP-dependent DNA helicase (RecQ)
CHR56_RS18385	COG2226	methyltransferase
CHR56_RS18395	COG1063	alcohol dehydrogenase
CHR56_RS18405	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CHR56_RS18435	COG1917	Cupin 2, conserved barrel domain protein
CHR56_RS18435	COG2207	Transcriptional regulator
CHR56_RS18445	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CHR56_RS18445	COG0072	phenylalanine-tRNA ligase activity
CHR56_RS18495	COG5507	3-demethylubiquinone-9 3-methyltransferase
CHR56_RS18500	COG0432	Pfam Uncharacterised protein family UPF0047
CHR56_RS18515	COG2968	Membrane
CHR56_RS18615	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CHR56_RS18665	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CHR56_RS18695	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CHR56_RS18765	COG1404	Belongs to the peptidase S8 family
CHR56_RS18820	COG3547	Transposase (IS116 IS110 IS902 family)
CHR56_RS18895	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CHR56_RS19000	COG3842	ATPase activity
CHR56_RS19010	COG1176	ABC-type spermidine putrescine transport system, permease component I
CHR56_RS19015	COG0395	ABC-type sugar transport system, permease component
CHR56_RS19025	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CHR56_RS19030	COG4702	Belongs to the UPF0303 family
CHR56_RS19050	COG2188	Transcriptional regulator
CHR56_RS19055	COG2971	BadF BadG BcrA BcrD
CHR56_RS19065	COG1175	transmembrane transport
CHR56_RS19070	COG0395	ABC-type sugar transport system, permease component
CHR56_RS19075	COG0673	inositol 2-dehydrogenase activity
CHR56_RS19090	COG3842	ATPase activity
CHR56_RS19095	COG2011	ABC-type metal ion transport system permease component
CHR56_RS19125	COG0174	glutamine synthetase
CHR56_RS19140	COG1192	Involved in chromosome partitioning
CHR56_RS19145	COG1116	anion transmembrane transporter activity
CHR56_RS19150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CHR56_RS19155	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CHR56_RS19160	COG1376	ErfK ybiS ycfS ynhG family protein
CHR56_RS19175	COG0251	oxidation-reduction process
CHR56_RS19180	COG0028	Belongs to the TPP enzyme family
CHR56_RS19185	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CHR56_RS19190	COG0697	spore germination
CHR56_RS19230	COG3757	hydrolase, family 25
CHR56_RS19255	COG1280	lysine exporter protein (LysE YggA)
CHR56_RS19265	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CHR56_RS19270	COG3023	N-Acetylmuramoyl-L-alanine amidase
CHR56_RS19295	COG2001	Belongs to the MraZ family
CHR56_RS19300	COG0275	rRNA processing
CHR56_RS19315	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CHR56_RS19325	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CHR56_RS19330	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CHR56_RS19340	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CHR56_RS19345	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CHR56_RS19350	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CHR56_RS19360	COG0477	Major facilitator Superfamily
CHR56_RS19365	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CHR56_RS19370	COG1181	Belongs to the D-alanine--D-alanine ligase family
CHR56_RS19375	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CHR56_RS19380	COG0849	cell division
CHR56_RS19385	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CHR56_RS19395	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CHR56_RS19410	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CHR56_RS19430	COG0835	chemotaxis
CHR56_RS19440	COG1999	signal sequence binding
CHR56_RS19445	COG2264	protein methyltransferase activity
CHR56_RS19450	COG0006	proline dipeptidase activity
CHR56_RS19475	COG1335	isochorismatase
CHR56_RS19500	COG2766	serine protein kinase
CHR56_RS19505	COG2718	Belongs to the UPF0229 family
CHR56_RS19510	COG2719	SpoVR family
CHR56_RS19525	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CHR56_RS19530	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CHR56_RS19535	COG2885	chlorophyll binding
CHR56_RS19550	COG3180	Ammonia monooxygenase
CHR56_RS19555	COG0583	DNA-binding transcription factor activity
CHR56_RS19560	COG0667	Aldo Keto reductase
CHR56_RS19565	COG0277	FAD linked oxidase domain protein
CHR56_RS19595	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CHR56_RS19605	COG0330	HflC and HflK could
CHR56_RS19610	COG0330	HflC and HflK could
CHR56_RS19620	COG0560	Phosphoserine phosphatase
CHR56_RS19625	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CHR56_RS19640	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CHR56_RS19650	COG0028	Belongs to the TPP enzyme family
CHR56_RS19655	COG0440	acetolactate synthase activity
CHR56_RS19665	COG0656	L-ascorbic acid biosynthetic process
CHR56_RS19725	COG1846	Transcriptional regulator
CHR56_RS19735	COG0668	transmembrane transport
CHR56_RS19765	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CHR56_RS19775	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CHR56_RS19785	COG1733	regulation of RNA biosynthetic process
CHR56_RS19790	COG2814	Major facilitator Superfamily
CHR56_RS19795	COG1309	transcriptional regulator
CHR56_RS19800	COG1846	Transcriptional regulator
CHR56_RS19800	COG0456	acetyltransferase
CHR56_RS19805	COG1794	racemase activity, acting on amino acids and derivatives
CHR56_RS19810	COG1522	sequence-specific DNA binding
CHR56_RS19815	COG1252	NADH dehydrogenase
CHR56_RS19830	COG1064	alcohol dehydrogenase
CHR56_RS19835	COG2207	Transcriptional regulator
CHR56_RS19850	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CHR56_RS19875	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CHR56_RS19880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CHR56_RS19885	COG5634	Uncharacterized conserved protein (DUF2278)
CHR56_RS19890	COG0667	Aldo Keto reductase
CHR56_RS19900	COG1176	ABC-type spermidine putrescine transport system, permease component I
CHR56_RS19905	COG3842	ATPase activity
CHR56_RS19925	COG0384	phenazine biosynthesis protein PhzF
CHR56_RS19960	COG1253	flavin adenine dinucleotide binding
CHR56_RS19980	COG0523	cobalamin synthesis protein
CHR56_RS19990	COG1121	(ABC) transporter
CHR56_RS19995	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CHR56_RS20120	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CHR56_RS20150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CHR56_RS20160	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CHR56_RS20190	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CHR56_RS20195	COG5002	protein histidine kinase activity
CHR56_RS20200	COG2204	response regulator
CHR56_RS20210	COG0840	transmembrane signaling receptor activity
CHR56_RS20215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CHR56_RS20220	COG0697	spore germination
CHR56_RS20225	COG2329	Antibiotic biosynthesis monooxygenase
CHR56_RS20240	COG1846	Transcriptional regulator
CHR56_RS20240	COG1940	carbohydrate kinase activity
CHR56_RS20255	COG0395	ABC-type sugar transport system, permease component
CHR56_RS20285	COG0501	Belongs to the peptidase M48B family
CHR56_RS20315	COG2208	phosphoserine phosphatase activity
CHR56_RS20320	COG2226	methyltransferase
CHR56_RS20330	COG3300	MHYT domain
CHR56_RS20330	COG5001	Diguanylate cyclase
CHR56_RS20335	COG0583	DNA-binding transcription factor activity
CHR56_RS20340	COG0662	Cupin 2, conserved barrel domain protein
CHR56_RS20410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CHR56_RS20430	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CHR56_RS20445	COG4372	Transposase
CHR56_RS20450	COG3436	PFAM IS66 Orf2 family protein
CHR56_RS20455	COG2963	transposase activity
CHR56_RS20490	COG0667	Aldo Keto reductase
CHR56_RS20495	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CHR56_RS20525	COG2201	protein-glutamate methylesterase activity
CHR56_RS20545	COG3453	Protein conserved in bacteria
CHR56_RS20545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CHR56_RS20560	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CHR56_RS20595	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CHR56_RS20600	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CHR56_RS20605	COG1845	cytochrome c oxidase, subunit III
CHR56_RS20630	COG0833	amino acid
CHR56_RS20660	COG1917	Cupin 2, conserved barrel domain protein
CHR56_RS20660	COG2207	Transcriptional regulator
CHR56_RS20670	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CHR56_RS20675	COG1136	(ABC) transporter
CHR56_RS20675	COG0577	efflux transmembrane transporter activity
CHR56_RS20690	COG0697	spore germination
CHR56_RS20730	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
CHR56_RS20735	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CHR56_RS20755	COG0025	NhaP-type Na H and K H
CHR56_RS20760	COG3158	transport of potassium into the cell
CHR56_RS20765	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CHR56_RS20770	COG2814	Major facilitator Superfamily
CHR56_RS20780	COG0738	Major facilitator superfamily
CHR56_RS20795	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CHR56_RS20825	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CHR56_RS20855	COG1132	(ABC) transporter
CHR56_RS20860	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
CHR56_RS20870	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CHR56_RS20880	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CHR56_RS20890	COG0137	argininosuccinate synthase activity
CHR56_RS20895	COG1522	sequence-specific DNA binding
CHR56_RS20905	COG0702	epimerase
CHR56_RS20925	COG0667	Aldo Keto reductase
CHR56_RS20970	COG0842	Transport permease protein
CHR56_RS20970	COG1129	ABC transporter
CHR56_RS20975	COG0431	NADPH-dependent FMN reductase
CHR56_RS20985	COG3850	Histidine kinase
CHR56_RS20985	COG5002	protein histidine kinase activity
CHR56_RS21005	COG2755	lipolytic protein G-D-S-L family
CHR56_RS21005	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CHR56_RS21040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CHR56_RS21045	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CHR56_RS21095	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
CHR56_RS21125	COG0629	single-stranded DNA binding
CHR56_RS21460	COG0456	acetyltransferase
CHR56_RS21465	COG0556	nucleotide-excision repair
CHR56_RS21480	COG3387	PFAM Glycoside hydrolase 15-related
CHR56_RS21500	COG3152	Membrane
CHR56_RS21545	COG0659	secondary active sulfate transmembrane transporter activity
CHR56_RS21550	COG0583	DNA-binding transcription factor activity
CHR56_RS21560	COG4221	oxidoreductase activity
CHR56_RS21575	COG2814	Major facilitator Superfamily
CHR56_RS21595	COG0667	Aldo Keto reductase
CHR56_RS21630	COG1607	acyl-coa hydrolase
CHR56_RS21655	COG2226	methyltransferase
CHR56_RS21660	COG1764	response to oxidative stress
CHR56_RS21670	COG0494	nUDIX hydrolase
CHR56_RS21675	COG0596	Alpha beta hydrolase
CHR56_RS21680	COG1846	Transcriptional regulator
CHR56_RS21690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHR56_RS21695	COG1126	abc transporter atp-binding protein
CHR56_RS21705	COG0765	amino acid transport
CHR56_RS21710	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CHR56_RS21715	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CHR56_RS21720	COG2375	cellular response to nickel ion
CHR56_RS21735	COG2186	Transcriptional regulator
CHR56_RS21745	COG0596	Alpha beta hydrolase
CHR56_RS21755	COG2249	NAD(P)H dehydrogenase (quinone) activity
CHR56_RS21770	COG2376	Dihydroxyacetone kinase
CHR56_RS21790	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CHR56_RS21795	COG1461	Dihydroxyacetone kinase
CHR56_RS21805	COG3842	ATPase activity
CHR56_RS21820	COG0395	ABC-type sugar transport system, permease component
CHR56_RS21825	COG1175	transmembrane transport
CHR56_RS21840	COG2814	Major facilitator Superfamily
CHR56_RS21845	COG0745	RESPONSE REGULATOR receiver
CHR56_RS21855	COG3264	Mechanosensitive ion channel
CHR56_RS21855	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CHR56_RS21870	COG0431	NADPH-dependent FMN reductase
CHR56_RS21880	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CHR56_RS21885	COG0640	Transcriptional regulator
CHR56_RS21910	COG0745	RESPONSE REGULATOR receiver
CHR56_RS21950	COG0668	transmembrane transport
CHR56_RS21970	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CHR56_RS21980	COG0583	DNA-binding transcription factor activity
CHR56_RS21995	COG0583	DNA-binding transcription factor activity
CHR56_RS22015	COG1492	cobalamin metabolic process
CHR56_RS22020	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS22135	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CHR56_RS22140	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CHR56_RS22150	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CHR56_RS22185	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CHR56_RS22195	COG3153	acetyltransferase
CHR56_RS22225	COG0583	DNA-binding transcription factor activity
CHR56_RS22230	COG0495	leucyl-tRNA aminoacylation
CHR56_RS22245	COG1175	transmembrane transport
CHR56_RS22250	COG0395	ABC-type sugar transport system, permease component
CHR56_RS22275	COG0667	Aldo Keto reductase
CHR56_RS22280	COG3507	Belongs to the glycosyl hydrolase 43 family
CHR56_RS22285	COG1131	(ABC) transporter
CHR56_RS22290	COG0842	Transport permease protein
CHR56_RS22295	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS22320	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CHR56_RS22325	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CHR56_RS22335	COG2202	Pas domain
CHR56_RS22335	COG2205	protein histidine kinase activity
CHR56_RS22345	COG1573	uracil-dna glycosylase
CHR56_RS22350	COG1522	sequence-specific DNA binding
CHR56_RS22365	COG0583	DNA-binding transcription factor activity
CHR56_RS22375	COG2084	Dehydrogenase
CHR56_RS22385	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CHR56_RS22395	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CHR56_RS22400	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CHR56_RS22405	COG1116	anion transmembrane transporter activity
CHR56_RS22445	COG0625	glutathione transferase activity
CHR56_RS22460	COG5425	PFAM Usg family protein
CHR56_RS22475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHR56_RS22485	COG1012	belongs to the aldehyde dehydrogenase family
CHR56_RS22490	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CHR56_RS22495	COG1349	DNA-binding transcription factor activity
CHR56_RS22520	COG2205	protein histidine kinase activity
CHR56_RS22525	COG1764	response to oxidative stress
CHR56_RS22540	COG0667	Aldo Keto reductase
CHR56_RS22555	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
CHR56_RS22560	COG4191	Histidine kinase
CHR56_RS22560	COG0784	Response regulator, receiver
CHR56_RS22565	COG1763	Mo-molybdopterin cofactor biosynthetic process
CHR56_RS22570	COG0746	molybdenum cofactor guanylyltransferase activity
CHR56_RS22580	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS22585	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CHR56_RS22590	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS22595	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS22605	COG1879	ABC-type sugar transport system periplasmic component
CHR56_RS22610	COG1172	Belongs to the binding-protein-dependent transport system permease family
CHR56_RS22615	COG3959	Transketolase, thiamine diphosphate binding domain
CHR56_RS22620	COG3958	Transketolase
CHR56_RS22625	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CHR56_RS22630	COG2390	Transcriptional regulator
CHR56_RS22635	COG1120	ATPase activity
CHR56_RS22640	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CHR56_RS22650	COG2226	methyltransferase
CHR56_RS22655	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CHR56_RS22695	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CHR56_RS22695	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CHR56_RS22705	COG0114	fumarate hydratase activity
CHR56_RS22710	COG2989	Protein conserved in bacteria
CHR56_RS22715	COG0546	phosphoglycolate phosphatase activity
CHR56_RS22720	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CHR56_RS22730	COG1254	Belongs to the acylphosphatase family
CHR56_RS22755	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CHR56_RS22760	COG1132	(ABC) transporter
CHR56_RS22790	COG0823	Involved in the tonB-independent uptake of proteins
CHR56_RS22795	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CHR56_RS22805	COG0840	transmembrane signaling receptor activity
CHR56_RS22810	COG0477	Major facilitator Superfamily
CHR56_RS22815	COG0778	Nitroreductase
CHR56_RS22820	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CHR56_RS22830	COG0384	phenazine biosynthesis protein PhzF
CHR56_RS22835	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS22845	COG0328	RNA-DNA hybrid ribonuclease activity
CHR56_RS22850	COG0281	malic enzyme
CHR56_RS22850	COG0280	phosphate acetyltransferase
CHR56_RS22860	COG0588	phosphoglycerate mutase activity
CHR56_RS22875	COG2814	Major facilitator Superfamily
CHR56_RS22880	COG4948	Mandelate Racemase Muconate Lactonizing
CHR56_RS22890	COG1127	ABC transporter
CHR56_RS22910	COG1686	Belongs to the peptidase S11 family
CHR56_RS22935	COG0633	Ferredoxin
CHR56_RS22945	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CHR56_RS22955	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CHR56_RS22965	COG3768	UPF0283 membrane protein
CHR56_RS22970	COG3106	COG3106 Predicted ATPase
CHR56_RS23000	COG2313	pseudouridylate synthase activity
CHR56_RS23010	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CHR56_RS23015	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CHR56_RS23020	COG1280	lysine exporter protein (LysE YggA)
CHR56_RS23040	COG0538	isocitrate dehydrogenase activity
CHR56_RS23055	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CHR56_RS23060	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CHR56_RS23065	COG2223	nitrite transmembrane transporter activity
CHR56_RS23075	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CHR56_RS23080	COG2066	Belongs to the glutaminase family
CHR56_RS23085	COG0037	tRNA processing
CHR56_RS23090	COG0483	inositol monophosphate 1-phosphatase activity
CHR56_RS23095	COG0483	inositol monophosphate 1-phosphatase activity
CHR56_RS23100	COG0454	-acetyltransferase
CHR56_RS23110	COG2814	Major facilitator Superfamily
CHR56_RS23115	COG2814	Major facilitator Superfamily
CHR56_RS23120	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CHR56_RS23145	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CHR56_RS23155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CHR56_RS23170	COG0047	phosphoribosylformylglycinamidine synthase activity
CHR56_RS23175	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
CHR56_RS23180	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CHR56_RS23185	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CHR56_RS23210	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CHR56_RS23235	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CHR56_RS23250	COG0513	Belongs to the DEAD box helicase family
CHR56_RS23255	COG0739	heme binding
CHR56_RS23255	COG0741	lytic transglycosylase activity
CHR56_RS23255	COG1196	nuclear chromosome segregation
CHR56_RS23260	COG2833	Protein of unknown function (DUF455)
CHR56_RS23265	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CHR56_RS23280	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CHR56_RS23285	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CHR56_RS23300	COG2945	thiolester hydrolase activity
CHR56_RS23305	COG1104	cysteine desulfurase activity
CHR56_RS23310	COG0719	Fe-S assembly protein
CHR56_RS23320	COG0396	ATPase activity
CHR56_RS23325	COG0719	Fe-S assembly protein
CHR56_RS23330	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CHR56_RS23335	COG2151	metal-sulfur cluster biosynthetic enzyme
CHR56_RS23340	COG0316	Belongs to the HesB IscA family
CHR56_RS23350	COG0243	molybdopterin cofactor binding
CHR56_RS23375	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CHR56_RS23375	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CHR56_RS23380	COG0509	glycine decarboxylation via glycine cleavage system
CHR56_RS23405	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CHR56_RS23415	COG0546	phosphoglycolate phosphatase activity
CHR56_RS23430	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CHR56_RS23435	COG2259	Doxx family
CHR56_RS23445	COG1671	Belongs to the UPF0178 family
CHR56_RS23455	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CHR56_RS23460	COG4770	biotin carboxylase activity
CHR56_RS23480	COG0321	lipoyl(octanoyl) transferase activity
CHR56_RS23500	COG0242	peptide deformylase activity
CHR56_RS23505	COG2239	Acts as a magnesium transporter
CHR56_RS23525	COG0698	ribose 5-phosphate isomerase
CHR56_RS23540	COG1760	l-serine dehydratase
CHR56_RS23555	COG1686	Belongs to the peptidase S11 family
CHR56_RS23570	COG2267	carboxylic ester hydrolase activity
CHR56_RS23595	COG1752	Esterase of the alpha-beta hydrolase superfamily
CHR56_RS23600	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CHR56_RS23605	COG0302	gtp cyclohydrolase
CHR56_RS23615	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CHR56_RS23625	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CHR56_RS23660	COG0628	permease
CHR56_RS23670	COG0187	DNA topoisomerase II activity
CHR56_RS23680	COG0149	triose-phosphate isomerase activity
CHR56_RS23690	COG0504	CTP synthase activity
CHR56_RS23700	COG0372	Belongs to the citrate synthase family
CHR56_RS23705	COG0372	Belongs to the citrate synthase family
CHR56_RS23720	COG0513	Belongs to the DEAD box helicase family
CHR56_RS23725	COG2153	protein acetylation
CHR56_RS23740	COG0303	'Molybdopterin
CHR56_RS23745	COG0315	cyclic pyranopterin monophosphate synthase activity
CHR56_RS23750	COG0134	indole-3-glycerol-phosphate synthase activity
CHR56_RS23755	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CHR56_RS23790	COG2824	Alkylphosphonate utilization operon protein PhnA
CHR56_RS23845	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CHR56_RS23855	COG0730	response to heat
CHR56_RS23860	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CHR56_RS23865	COG0084	hydrolase, TatD family'
CHR56_RS23870	COG0321	lipoyl(octanoyl) transferase activity
CHR56_RS23870	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CHR56_RS23875	COG0861	Integral membrane protein TerC family
CHR56_RS23890	COG3174	membrane
CHR56_RS23905	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CHR56_RS23915	COG1984	allophanate hydrolase subunit 2
CHR56_RS23925	COG0583	DNA-binding transcription factor activity
CHR56_RS23940	COG0596	Alpha beta hydrolase
CHR56_RS23945	COG0668	transmembrane transport
CHR56_RS23950	COG1172	Belongs to the binding-protein-dependent transport system permease family
CHR56_RS23955	COG1129	ABC transporter
CHR56_RS23965	COG1609	Transcriptional regulator
CHR56_RS23970	COG0028	Belongs to the TPP enzyme family
CHR56_RS24000	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CHR56_RS24025	COG0612	Peptidase, M16
CHR56_RS24070	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CHR56_RS24080	COG0343	queuine tRNA-ribosyltransferase activity
CHR56_RS24085	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CHR56_RS24100	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CHR56_RS24110	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CHR56_RS24115	COG2095	MarC family integral membrane protein
CHR56_RS24120	COG0629	single-stranded DNA binding
CHR56_RS24125	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CHR56_RS24140	COG2354	Protein conserved in bacteria
CHR56_RS24145	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CHR56_RS24145	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CHR56_RS24150	COG0347	Belongs to the P(II) protein family
CHR56_RS24155	COG0174	glutamine synthetase
CHR56_RS24170	COG4166	transmembrane transport
CHR56_RS24185	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CHR56_RS24195	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CHR56_RS24205	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CHR56_RS24210	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CHR56_RS24215	COG2186	Transcriptional regulator
CHR56_RS24220	COG1172	Belongs to the binding-protein-dependent transport system permease family
CHR56_RS24225	COG1172	Belongs to the binding-protein-dependent transport system permease family
CHR56_RS24230	COG1129	ABC transporter
CHR56_RS24235	COG1879	ABC-type sugar transport system periplasmic component
CHR56_RS24245	COG1079	Belongs to the binding-protein-dependent transport system permease family
CHR56_RS24255	COG3845	ABC transporter
CHR56_RS24265	COG1183	phosphatidylcholine synthase activity
CHR56_RS24285	COG1136	(ABC) transporter
CHR56_RS24285	COG0577	efflux transmembrane transporter activity
CHR56_RS24290	COG0577	efflux transmembrane transporter activity
CHR56_RS24290	COG1136	(ABC) transporter
CHR56_RS24295	COG1566	PFAM secretion protein HlyD family protein
CHR56_RS24375	COG0395	ABC-type sugar transport system, permease component
CHR56_RS24380	COG1175	transmembrane transport
CHR56_RS24400	COG4608	Belongs to the ABC transporter superfamily
CHR56_RS24405	COG0444	Belongs to the ABC transporter superfamily
CHR56_RS24410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHR56_RS24415	COG0601	transmembrane transport
CHR56_RS24425	COG2186	Transcriptional regulator
CHR56_RS24430	COG1312	Catalyzes the dehydration of D-mannonate
CHR56_RS24435	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CHR56_RS24450	COG3842	ATPase activity
CHR56_RS24455	COG0395	ABC-type sugar transport system, permease component
CHR56_RS24460	COG1175	transmembrane transport
CHR56_RS24465	COG1653	transport
CHR56_RS24540	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CHR56_RS24550	COG3237	CsbD-like
CHR56_RS24570	COG0785	Cytochrome C biogenesis protein
CHR56_RS24575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CHR56_RS24580	COG0679	Auxin Efflux Carrier
CHR56_RS24585	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CHR56_RS24595	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CHR56_RS24605	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CHR56_RS24605	COG1648	precorrin-2 dehydrogenase activity
CHR56_RS24615	COG3956	TIGRFAM MazG family protein
CHR56_RS24620	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CHR56_RS24625	COG1923	regulation of RNA biosynthetic process
CHR56_RS24630	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CHR56_RS24635	COG2204	response regulator
CHR56_RS24640	COG5000	phosphorelay sensor kinase activity
CHR56_RS24645	COG0667	Aldo Keto reductase
CHR56_RS24655	COG2204	response regulator
CHR56_RS24675	COG2204	response regulator
CHR56_RS24690	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CHR56_RS24690	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CHR56_RS24695	COG1546	Belongs to the CinA family
CHR56_RS24695	COG1058	Belongs to the CinA family
CHR56_RS24700	COG2867	negative regulation of translational initiation
CHR56_RS24705	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CHR56_RS24715	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CHR56_RS24730	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CHR56_RS24745	COG0508	dehydrogenase complex catalyzes the overall conversion of
CHR56_RS24750	COG0508	dehydrogenase complex catalyzes the overall conversion of
CHR56_RS24750	COG0022	dehydrogenase e1 component
CHR56_RS24755	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CHR56_RS24765	COG0148	phosphopyruvate hydratase activity
CHR56_RS24770	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CHR56_RS24780	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CHR56_RS24795	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CHR56_RS24800	COG3494	Protein of unknown function (DUF1009)
CHR56_RS24805	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CHR56_RS24810	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CHR56_RS24815	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CHR56_RS24820	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CHR56_RS24825	COG0750	zinc metalloprotease
CHR56_RS24835	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CHR56_RS24840	COG0233	cytoplasmic translational termination
CHR56_RS24845	COG0528	UMP kinase activity
CHR56_RS24850	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CHR56_RS24855	COG0052	Belongs to the universal ribosomal protein uS2 family
CHR56_RS24880	COG0537	adenosine 5'-monophosphoramidase activity
CHR56_RS24890	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CHR56_RS24910	COG2267	carboxylic ester hydrolase activity
CHR56_RS24925	COG0626	cystathionine gamma-synthase activity
CHR56_RS24930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHR56_RS24935	COG4597	amino acid ABC transporter
CHR56_RS24940	COG0765	amino acid transport
CHR56_RS24945	COG1126	abc transporter atp-binding protein
CHR56_RS24990	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CHR56_RS25035	COG3420	alginic acid biosynthetic process
CHR56_RS25050	COG2197	response regulator
CHR56_RS25055	COG0463	Glycosyl transferase, family 2
CHR56_RS25055	COG1216	Glycosyl transferase, family 2
CHR56_RS25285	COG3756	Protein conserved in bacteria
CHR56_RS25340	COG3750	Belongs to the UPF0335 family
CHR56_RS25465	COG0022	dehydrogenase e1 component
CHR56_RS25495	COG0583	DNA-binding transcription factor activity
CHR56_RS25500	COG4336	lyase activity
CHR56_RS25510	COG3842	ATPase activity
CHR56_RS25515	COG1176	ABC-type spermidine putrescine transport system, permease component I
CHR56_RS25525	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CHR56_RS25530	COG0022	dehydrogenase e1 component
CHR56_RS25540	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS25555	COG0583	DNA-binding transcription factor activity
CHR56_RS25560	COG0673	inositol 2-dehydrogenase activity
CHR56_RS25570	COG1609	Transcriptional regulator
CHR56_RS25580	COG1082	Xylose isomerase domain protein TIM barrel
CHR56_RS25585	COG1609	Transcriptional regulator
CHR56_RS25595	COG1129	ABC transporter
CHR56_RS25600	COG1172	Belongs to the binding-protein-dependent transport system permease family
CHR56_RS25605	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CHR56_RS25610	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CHR56_RS25615	COG4770	biotin carboxylase activity
CHR56_RS25620	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CHR56_RS25625	COG0277	FAD linked oxidase domain protein
CHR56_RS25630	COG0277	FAD linked oxidase domain protein
CHR56_RS25635	COG0247	lactate metabolic process
CHR56_RS25640	COG1414	Transcriptional regulator
CHR56_RS25645	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CHR56_RS25650	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CHR56_RS25655	COG3616	Alanine racemase, N-terminal domain
CHR56_RS25660	COG2423	ornithine cyclodeaminase activity
CHR56_RS25695	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CHR56_RS25700	COG3842	ATPase activity
CHR56_RS25705	COG3833	ABC-type maltose transport systems, permease component
CHR56_RS25730	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CHR56_RS25735	COG0022	dehydrogenase e1 component
CHR56_RS25735	COG0508	dehydrogenase complex catalyzes the overall conversion of
CHR56_RS25740	COG0508	dehydrogenase complex catalyzes the overall conversion of
CHR56_RS25745	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CHR56_RS25755	COG0840	transmembrane signaling receptor activity
CHR56_RS25755	COG2972	Histidine kinase
CHR56_RS25765	COG2972	Histidine kinase
CHR56_RS25765	COG0840	transmembrane signaling receptor activity
CHR56_RS25770	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CHR56_RS25790	COG3220	belongs to the UPF0276 family
CHR56_RS25835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CHR56_RS25860	COG0559	Belongs to the binding-protein-dependent transport system permease family
CHR56_RS25880	COG1024	Enoyl-CoA hydratase
CHR56_RS25890	COG0318	PFAM AMP-dependent synthetase and ligase
CHR56_RS25895	COG1454	alcohol dehydrogenase
CHR56_RS25910	COG0563	adenylate kinase activity
CHR56_RS25915	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CHR56_RS25935	COG0395	ABC-type sugar transport system, permease component
CHR56_RS25940	COG1175	transmembrane transport
CHR56_RS25950	COG3842	ATPase activity
CHR56_RS25955	COG0346	lactoylglutathione lyase activity
CHR56_RS25965	COG0277	FAD linked oxidase domain protein
CHR56_RS25980	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CHR56_RS26015	COG2086	electron transfer activity
CHR56_RS26070	COG0179	Fumarylacetoacetate (FAA) hydrolase
CHR56_RS26075	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CHR56_RS26080	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CHR56_RS26085	COG1012	belongs to the aldehyde dehydrogenase family
CHR56_RS26100	COG3609	addiction module antidote protein, CC2985 family
CHR56_RS26120	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
CHR56_RS26135	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CHR56_RS26140	COG4977	sequence-specific DNA binding
CHR56_RS26180	COG0523	cobalamin synthesis protein
CHR56_RS26205	COG2022	thiamine diphosphate biosynthetic process
CHR56_RS26245	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CHR56_RS26255	COG2390	Transcriptional regulator
CHR56_RS26260	COG0371	Dehydrogenase
CHR56_RS26275	COG1175	transmembrane transport
CHR56_RS26280	COG0395	ABC-type sugar transport system, permease component
CHR56_RS26290	COG4221	oxidoreductase activity
CHR56_RS26295	COG3842	ATPase activity
CHR56_RS26300	COG3347	Dehydrogenase
CHR56_RS26300	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS26305	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CHR56_RS26325	COG1162	GTPase activity
CHR56_RS26360	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CHR56_RS26365	COG4372	Transposase
CHR56_RS26380	COG4166	transmembrane transport
CHR56_RS26390	COG1609	Transcriptional regulator
CHR56_RS26395	COG1129	ABC transporter
CHR56_RS26400	COG1172	Belongs to the binding-protein-dependent transport system permease family
CHR56_RS26410	COG0673	inositol 2-dehydrogenase activity
CHR56_RS26445	COG0840	transmembrane signaling receptor activity
CHR56_RS26455	COG0402	S-adenosylhomocysteine deaminase activity
CHR56_RS26480	COG2072	flavoprotein involved in K transport
CHR56_RS26485	COG1177	transmembrane transport
CHR56_RS26490	COG1176	ABC-type spermidine putrescine transport system, permease component I
CHR56_RS26495	COG3842	ATPase activity
CHR56_RS26500	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CHR56_RS26505	COG0583	DNA-binding transcription factor activity
CHR56_RS26520	COG0511	ligase activity, forming carbon-carbon bonds
CHR56_RS26525	COG0439	Biotin carboxylase
CHR56_RS26535	COG1984	allophanate hydrolase subunit 2
CHR56_RS26545	COG3842	ATPase activity
CHR56_RS26550	COG1176	ABC-type spermidine putrescine transport system, permease component I
CHR56_RS26560	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS26565	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS26575	COG3842	ATPase activity
CHR56_RS26580	COG0726	polysaccharide deacetylase
CHR56_RS26590	COG0523	cobalamin synthesis protein
CHR56_RS26610	COG1454	alcohol dehydrogenase
CHR56_RS26620	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CHR56_RS26625	COG0411	ABC transporter
CHR56_RS26655	COG1846	Transcriptional regulator
CHR56_RS26660	COG2309	aminopeptidase activity
CHR56_RS26665	COG1335	isochorismatase
CHR56_RS26670	COG3473	Maleate cis-trans isomerase
CHR56_RS26675	COG0596	Alpha beta hydrolase
CHR56_RS26680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CHR56_RS26685	COG2080	2 iron, 2 sulfur cluster binding
CHR56_RS26690	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CHR56_RS26690	COG2010	Cytochrome c
CHR56_RS26705	COG1840	ABC-type Fe3 transport system, periplasmic component
CHR56_RS26710	COG1176	ABC-type spermidine putrescine transport system, permease component I
CHR56_RS26715	COG1177	transmembrane transport
CHR56_RS26720	COG3842	ATPase activity
CHR56_RS26730	COG1846	Transcriptional regulator
CHR56_RS26735	COG1472	Belongs to the glycosyl hydrolase 3 family
CHR56_RS26745	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CHR56_RS26745	COG3608	succinylglutamate desuccinylase aspartoacylase
CHR56_RS26755	COG0746	molybdenum cofactor guanylyltransferase activity
CHR56_RS26830	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CHR56_RS26835	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CHR56_RS26850	COG2188	Transcriptional regulator
CHR56_RS26855	COG1063	alcohol dehydrogenase
CHR56_RS26865	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS26870	COG1733	regulation of RNA biosynthetic process
CHR56_RS26875	COG2085	NADP oxidoreductase coenzyme F420-dependent
CHR56_RS26905	COG0300	oxidoreductase activity
CHR56_RS26955	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS27005	COG2963	transposase activity
CHR56_RS27010	COG3436	PFAM IS66 Orf2 family protein
CHR56_RS27015	COG4372	Transposase
CHR56_RS27065	COG3920	Histidine kinase
CHR56_RS27065	COG2202	Pas domain
CHR56_RS27080	COG0071	Belongs to the small heat shock protein (HSP20) family
CHR56_RS27085	COG0071	Belongs to the small heat shock protein (HSP20) family
CHR56_RS27145	COG3831	ATPase activity
CHR56_RS27160	COG2161	toxin-antitoxin pair type II binding
CHR56_RS27170	COG3505	Type IV secretory pathway VirD4
CHR56_RS27200	COG0745	RESPONSE REGULATOR receiver
CHR56_RS27205	COG0156	8-amino-7-oxononanoate synthase activity
CHR56_RS27215	COG1177	transmembrane transport
CHR56_RS27220	COG1176	ABC-type spermidine putrescine transport system, permease component I
CHR56_RS27225	COG3842	ATPase activity
CHR56_RS27235	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CHR56_RS27245	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS27250	COG0745	RESPONSE REGULATOR receiver
CHR56_RS27255	COG1595	DNA-templated transcription, initiation
CHR56_RS27275	COG1012	belongs to the aldehyde dehydrogenase family
CHR56_RS27285	COG4177	L-phenylalanine transmembrane transporter activity
CHR56_RS27300	COG1137	ATPase activity
CHR56_RS27345	COG1024	Enoyl-CoA hydratase
CHR56_RS27355	COG1012	belongs to the aldehyde dehydrogenase family
CHR56_RS27360	COG2203	Gaf domain
CHR56_RS27360	COG3706	GGDEF domain
CHR56_RS27360	COG4251	negative regulation of phosphorylation
CHR56_RS27360	COG5001	Diguanylate cyclase
CHR56_RS27365	COG0243	molybdopterin cofactor binding
CHR56_RS27390	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CHR56_RS27400	COG4176	ABC-type proline glycine betaine transport system permease component
CHR56_RS27410	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CHR56_RS27420	COG1902	pentaerythritol trinitrate reductase activity
CHR56_RS27420	COG0446	pyridine nucleotide-disulphide oxidoreductase
CHR56_RS27430	COG2086	electron transfer activity
CHR56_RS27445	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CHR56_RS27450	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CHR56_RS27455	COG3791	Glutathione-dependent formaldehyde-activating
CHR56_RS27460	COG1802	Transcriptional regulator
CHR56_RS27465	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CHR56_RS27470	COG1012	belongs to the aldehyde dehydrogenase family
CHR56_RS27475	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CHR56_RS27485	COG4175	Glycine betaine
CHR56_RS27485	COG3448	diguanylate cyclase activity
CHR56_RS27490	COG4176	ABC-type proline glycine betaine transport system permease component
CHR56_RS27495	COG4176	ABC-type proline glycine betaine transport system permease component
CHR56_RS27500	COG3938	Belongs to the proline racemase family
CHR56_RS27510	COG0006	proline dipeptidase activity
CHR56_RS27525	COG0583	DNA-binding transcription factor activity
CHR56_RS27535	COG3706	GGDEF domain
CHR56_RS27535	COG4251	negative regulation of phosphorylation
CHR56_RS27535	COG5001	Diguanylate cyclase
CHR56_RS27535	COG2203	Gaf domain
CHR56_RS27550	COG4221	oxidoreductase activity
CHR56_RS27565	COG1522	sequence-specific DNA binding
CHR56_RS27580	COG4948	Mandelate Racemase Muconate Lactonizing
CHR56_RS27585	COG4948	Mandelate Racemase Muconate Lactonizing
CHR56_RS27600	COG1653	transport
CHR56_RS27615	COG3842	ATPase activity
CHR56_RS27620	COG4948	Mandelate Racemase Muconate Lactonizing
CHR56_RS27645	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CHR56_RS27650	COG1522	sequence-specific DNA binding
CHR56_RS27655	COG4172	Belongs to the ABC transporter superfamily
CHR56_RS27665	COG0601	transmembrane transport
CHR56_RS27690	COG3395	kinase activity
CHR56_RS27695	COG3622	Belongs to the hyi family
CHR56_RS27700	COG2084	Dehydrogenase
CHR56_RS27710	COG1609	Transcriptional regulator
CHR56_RS27715	COG0235	Class ii aldolase
CHR56_RS27725	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CHR56_RS27730	COG1012	belongs to the aldehyde dehydrogenase family
CHR56_RS27735	COG0473	3-isopropylmalate dehydrogenase activity
CHR56_RS27740	COG1012	belongs to the aldehyde dehydrogenase family
CHR56_RS27750	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CHR56_RS27755	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CHR56_RS27805	COG0559	Belongs to the binding-protein-dependent transport system permease family
CHR56_RS27825	COG0436	Aminotransferase
CHR56_RS27830	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CHR56_RS27835	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CHR56_RS27845	COG2186	Transcriptional regulator
CHR56_RS27850	COG0247	lactate metabolic process
CHR56_RS27850	COG0277	FAD linked oxidase domain protein
CHR56_RS27855	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS27860	COG4221	oxidoreductase activity
CHR56_RS27870	COG0459	protein refolding
CHR56_RS27875	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CHR56_RS27930	COG3842	ATPase activity
CHR56_RS27940	COG0395	ABC-type sugar transport system, permease component
CHR56_RS27945	COG1175	transmembrane transport
CHR56_RS27970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CHR56_RS27980	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CHR56_RS27995	COG2186	Transcriptional regulator
CHR56_RS28000	COG1609	Transcriptional regulator
CHR56_RS28015	COG1175	transmembrane transport
CHR56_RS28020	COG0395	ABC-type sugar transport system, permease component
CHR56_RS28035	COG0840	transmembrane signaling receptor activity
CHR56_RS28060	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CHR56_RS28070	COG3842	ATPase activity
CHR56_RS28075	COG1175	transmembrane transport
CHR56_RS28080	COG0395	ABC-type sugar transport system, permease component
CHR56_RS28105	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CHR56_RS28115	COG1953	Uracil, thiamine, allantoin
CHR56_RS28120	COG0840	transmembrane signaling receptor activity
CHR56_RS28130	COG0598	Magnesium transport protein CorA
CHR56_RS28140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CHR56_RS28150	COG0366	Alpha amylase catalytic
CHR56_RS28155	COG0366	Alpha amylase catalytic
CHR56_RS28160	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CHR56_RS28165	COG1120	ATPase activity
CHR56_RS28210	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CHR56_RS28215	COG1640	4-alpha-glucanotransferase
CHR56_RS28265	COG2909	trisaccharide binding
CHR56_RS28270	COG1609	Transcriptional regulator
CHR56_RS28275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHR56_RS28290	COG2972	Histidine kinase
CHR56_RS28290	COG0840	transmembrane signaling receptor activity
CHR56_RS28305	COG0392	lysyltransferase activity
CHR56_RS28310	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CHR56_RS28325	COG0697	spore germination
CHR56_RS28330	COG2814	Major facilitator Superfamily
CHR56_RS28340	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CHR56_RS28380	COG1129	ABC transporter
CHR56_RS28385	COG1172	Belongs to the binding-protein-dependent transport system permease family
CHR56_RS28395	COG0667	Aldo Keto reductase
CHR56_RS28400	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CHR56_RS28410	COG1070	Carbohydrate kinase
CHR56_RS28420	COG1278	Cold shock
CHR56_RS28435	COG0583	DNA-binding transcription factor activity
CHR56_RS28440	COG2855	membrane
CHR56_RS28455	COG2030	dehydratase
CHR56_RS28465	COG2986	histidine ammonia-lyase
CHR56_RS28485	COG1174	glycine betaine transport
CHR56_RS28490	COG1174	glycine betaine transport
CHR56_RS28510	COG3842	ATPase activity
CHR56_RS28520	COG1175	transmembrane transport
CHR56_RS28525	COG0395	ABC-type sugar transport system, permease component
CHR56_RS28550	COG1129	ABC transporter
CHR56_RS28555	COG1172	Belongs to the binding-protein-dependent transport system permease family
CHR56_RS28560	COG1737	Transcriptional regulator
CHR56_RS28565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CHR56_RS28570	COG4608	Belongs to the ABC transporter superfamily
CHR56_RS28575	COG0444	Belongs to the ABC transporter superfamily
CHR56_RS28580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHR56_RS28585	COG0601	transmembrane transport
CHR56_RS28590	COG0747	negative chemotaxis
CHR56_RS28595	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CHR56_RS28600	COG3386	PFAM SMP-30 Gluconolaconase
CHR56_RS28605	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CHR56_RS28610	COG2186	Transcriptional regulator
CHR56_RS28615	COG0747	negative chemotaxis
CHR56_RS28620	COG0601	transmembrane transport
CHR56_RS28625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHR56_RS28630	COG4172	Belongs to the ABC transporter superfamily
CHR56_RS28635	COG4948	Mandelate Racemase Muconate Lactonizing
CHR56_RS28665	COG4566	intracellular signal transduction
CHR56_RS28670	COG0745	RESPONSE REGULATOR receiver
CHR56_RS28675	COG4566	intracellular signal transduction
CHR56_RS28680	COG4191	Histidine kinase
CHR56_RS28730	COG4191	Histidine kinase
CHR56_RS28740	COG2235	arginine
CHR56_RS28755	COG0531	amino acid
CHR56_RS28775	COG1982	Orn Lys Arg decarboxylase major
CHR56_RS28780	COG0531	amino acid
CHR56_RS28805	COG0628	permease
CHR56_RS28835	COG2954	triphosphatase activity
CHR56_RS28855	COG1192	Involved in chromosome partitioning
CHR56_RS28860	COG1475	DNA binding
CHR56_RS28865	COG1414	Transcriptional regulator
CHR56_RS28870	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CHR56_RS28885	COG1175	transmembrane transport
CHR56_RS28890	COG3833	ABC-type maltose transport systems, permease component
CHR56_RS28895	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CHR56_RS28900	COG0395	ABC-type sugar transport system, permease component
CHR56_RS28905	COG1175	transmembrane transport
CHR56_RS28920	COG0657	acetylesterase activity
CHR56_RS28935	COG1349	DNA-binding transcription factor activity
CHR56_RS28945	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CHR56_RS28965	COG2267	carboxylic ester hydrolase activity
CHR56_RS28970	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CHR56_RS28975	COG1940	carbohydrate kinase activity
CHR56_RS28985	COG0840	transmembrane signaling receptor activity
CHR56_RS29030	COG1749	Flagellar hook protein flgE
CHR56_RS29040	COG1309	transcriptional regulator
CHR56_RS29055	COG1024	Enoyl-CoA hydratase
CHR56_RS29060	COG1309	transcriptional regulator
CHR56_RS29065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHR56_RS29070	COG0765	amino acid transport
CHR56_RS29075	COG0765	amino acid transport
CHR56_RS29100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHR56_RS29105	COG0765	amino acid transport
CHR56_RS29110	COG0765	amino acid transport
CHR56_RS29140	COG2826	transposase and inactivated derivatives, IS30 family
CHR56_RS29150	COG1309	transcriptional regulator
CHR56_RS29175	COG1177	transmembrane transport
CHR56_RS29185	COG3842	ATPase activity
CHR56_RS29205	COG2909	trisaccharide binding
CHR56_RS29230	COG1129	ABC transporter
CHR56_RS29235	COG1172	Belongs to the binding-protein-dependent transport system permease family
CHR56_RS29240	COG1172	Belongs to the binding-protein-dependent transport system permease family
CHR56_RS29245	COG3547	Transposase (IS116 IS110 IS902 family)
CHR56_RS29260	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CHR56_RS29265	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CHR56_RS29270	COG1349	DNA-binding transcription factor activity
CHR56_RS29275	COG1879	ABC-type sugar transport system periplasmic component
CHR56_RS29280	COG1172	Belongs to the binding-protein-dependent transport system permease family
CHR56_RS29285	COG1129	ABC transporter
CHR56_RS29320	COG1349	DNA-binding transcription factor activity
CHR56_RS29325	COG0149	triose-phosphate isomerase activity
CHR56_RS29330	COG0698	ribose 5-phosphate isomerase
CHR56_RS29350	COG0395	ABC-type sugar transport system, permease component
CHR56_RS29355	COG1175	transmembrane transport
CHR56_RS29365	COG3842	ATPase activity
CHR56_RS29370	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CHR56_RS29375	COG2186	Transcriptional regulator
CHR56_RS29385	COG0747	negative chemotaxis
CHR56_RS29390	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CHR56_RS29400	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CHR56_RS29420	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CHR56_RS29430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHR56_RS29450	COG1051	belongs to the nudix hydrolase family
CHR56_RS29460	COG3842	ATPase activity
CHR56_RS29465	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
CHR56_RS29470	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CHR56_RS29475	COG0395	ABC-type sugar transport system, permease component
CHR56_RS29480	COG1175	transmembrane transport
CHR56_RS29485	COG2182	Extracellular solute-binding protein
CHR56_RS29490	COG2971	BadF BadG BcrA BcrD
CHR56_RS29495	COG1349	DNA-binding transcription factor activity
CHR56_RS29500	COG1486	melibiose metabolic process
CHR56_RS29510	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CHR56_RS29535	COG3842	ATPase activity
CHR56_RS29545	COG0765	amino acid transport
CHR56_RS29555	COG2186	Transcriptional regulator
CHR56_RS29580	COG1609	Transcriptional regulator
CHR56_RS29595	COG0395	ABC-type sugar transport system, permease component
CHR56_RS29600	COG3842	ATPase activity
CHR56_RS29605	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
CHR56_RS29620	COG1012	belongs to the aldehyde dehydrogenase family
CHR56_RS29645	COG0793	Belongs to the peptidase S41A family
CHR56_RS29655	COG1473	amidohydrolase
CHR56_RS29660	COG1126	abc transporter atp-binding protein
CHR56_RS29665	COG0765	amino acid transport
CHR56_RS29690	COG4585	Histidine kinase
CHR56_RS29695	COG1879	ABC-type sugar transport system periplasmic component
CHR56_RS29700	COG1129	ABC transporter
CHR56_RS29705	COG1172	Belongs to the binding-protein-dependent transport system permease family
CHR56_RS29720	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CHR56_RS29730	COG1846	Transcriptional regulator
CHR56_RS29735	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS29745	COG0583	DNA-binding transcription factor activity
CHR56_RS29755	COG1309	transcriptional regulator
CHR56_RS29770	COG0318	PFAM AMP-dependent synthetase and ligase
CHR56_RS29780	COG1802	Transcriptional regulator
CHR56_RS29815	COG0402	S-adenosylhomocysteine deaminase activity
CHR56_RS29825	COG2249	NAD(P)H dehydrogenase (quinone) activity
CHR56_RS29830	COG0251	oxidation-reduction process
CHR56_RS29835	COG3246	L-lysine catabolic process to acetate
CHR56_RS29845	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CHR56_RS29850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHR56_RS29855	COG0765	amino acid transport
CHR56_RS29860	COG1126	abc transporter atp-binding protein
CHR56_RS29875	COG0840	transmembrane signaling receptor activity
CHR56_RS29875	COG2972	Histidine kinase
CHR56_RS29890	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CHR56_RS29910	COG0626	cystathionine gamma-synthase activity
CHR56_RS29930	COG4774	siderophore transport
CHR56_RS29980	COG0277	FAD linked oxidase domain protein
CHR56_RS29995	COG0601	transmembrane transport
CHR56_RS30000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHR56_RS30005	COG4172	Belongs to the ABC transporter superfamily
CHR56_RS30015	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CHR56_RS30025	COG0431	NADPH-dependent FMN reductase
CHR56_RS30030	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CHR56_RS30050	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CHR56_RS30055	COG3706	GGDEF domain
CHR56_RS30060	COG2186	Transcriptional regulator
CHR56_RS30065	COG0747	negative chemotaxis
CHR56_RS30080	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CHR56_RS30085	COG0444	Belongs to the ABC transporter superfamily
CHR56_RS30115	COG0405	Gamma-glutamyltransferase
CHR56_RS30125	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHR56_RS30130	COG0444	Belongs to the ABC transporter superfamily
CHR56_RS30135	COG4608	Belongs to the ABC transporter superfamily
CHR56_RS30140	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CHR56_RS30165	COG2885	chlorophyll binding
CHR56_RS30190	COG0673	inositol 2-dehydrogenase activity
CHR56_RS30200	COG1175	transmembrane transport
CHR56_RS30205	COG0395	ABC-type sugar transport system, permease component
CHR56_RS30210	COG1940	carbohydrate kinase activity
CHR56_RS30220	COG3842	ATPase activity
CHR56_RS30225	COG2972	Histidine kinase
CHR56_RS30225	COG0840	transmembrane signaling receptor activity
CHR56_RS30230	COG1858	cytochrome C peroxidase
CHR56_RS30240	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CHR56_RS30245	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CHR56_RS30285	COG2197	response regulator
CHR56_RS30305	COG1733	regulation of RNA biosynthetic process
CHR56_RS30310	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS30310	COG3321	synthase
CHR56_RS30310	COG0604	alcohol dehydrogenase
CHR56_RS30320	COG0318	PFAM AMP-dependent synthetase and ligase
CHR56_RS30325	COG0183	Belongs to the thiolase family
CHR56_RS30330	COG5002	protein histidine kinase activity
CHR56_RS30335	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CHR56_RS30355	COG1295	ribonuclease BN
CHR56_RS30365	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CHR56_RS30380	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS30385	COG1461	Dihydroxyacetone kinase
CHR56_RS30390	COG2376	Dihydroxyacetone kinase
CHR56_RS30400	COG0673	inositol 2-dehydrogenase activity
CHR56_RS30405	COG1172	Belongs to the binding-protein-dependent transport system permease family
CHR56_RS30410	COG1129	ABC transporter
CHR56_RS30425	COG0287	Prephenate dehydrogenase
CHR56_RS30440	COG2186	Transcriptional regulator
CHR56_RS30455	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CHR56_RS30465	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CHR56_RS30470	COG1063	alcohol dehydrogenase
CHR56_RS30490	COG1079	Belongs to the binding-protein-dependent transport system permease family
CHR56_RS30505	COG0436	Aminotransferase
CHR56_RS30525	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS30535	COG3961	Belongs to the TPP enzyme family
CHR56_RS30550	COG1082	Xylose isomerase domain protein TIM barrel
CHR56_RS30590	COG1522	sequence-specific DNA binding
CHR56_RS30595	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CHR56_RS30600	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CHR56_RS30610	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CHR56_RS30620	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CHR56_RS30665	COG3838	Conjugal transfer protein Trbc
CHR56_RS30670	COG3702	type iv secretory pathway
CHR56_RS30675	COG3451	type IV secretory pathway VirB4
CHR56_RS30690	COG3704	protein secretion by the type IV secretion system
CHR56_RS30700	COG3736	Type IV secretory pathway, component VirB8
CHR56_RS30705	COG3504	Conjugal transfer protein
CHR56_RS30710	COG2948	multi-organism process
CHR56_RS30715	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
CHR56_RS30760	COG2345	Transcriptional regulator
CHR56_RS30780	COG1401	restriction endodeoxyribonuclease activity
CHR56_RS30840	COG0840	transmembrane signaling receptor activity
CHR56_RS30860	COG0673	inositol 2-dehydrogenase activity
CHR56_RS30865	COG0673	inositol 2-dehydrogenase activity
CHR56_RS30875	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CHR56_RS30885	COG1082	Xylose isomerase domain protein TIM barrel
CHR56_RS30890	COG1172	Belongs to the binding-protein-dependent transport system permease family
CHR56_RS30895	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CHR56_RS30900	COG0022	dehydrogenase e1 component
CHR56_RS30910	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS30930	COG0583	DNA-binding transcription factor activity
CHR56_RS30935	COG4336	lyase activity
CHR56_RS30945	COG3842	ATPase activity
CHR56_RS30980	COG1132	(ABC) transporter
CHR56_RS30985	COG1132	(ABC) transporter
CHR56_RS30995	COG1609	Transcriptional regulator
CHR56_RS31000	COG1609	Transcriptional regulator
CHR56_RS31010	COG2814	Major facilitator Superfamily
CHR56_RS31020	COG0784	Response regulator, receiver
CHR56_RS31035	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CHR56_RS31045	COG4953	penicillin-binding protein 1C
CHR56_RS31080	COG0670	Belongs to the BI1 family
CHR56_RS31090	COG1414	Transcriptional regulator
CHR56_RS31095	COG1475	DNA binding
CHR56_RS31100	COG1192	Involved in chromosome partitioning
CHR56_RS31150	COG1609	Transcriptional regulator
CHR56_RS31170	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CHR56_RS31180	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CHR56_RS31185	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CHR56_RS31220	COG1396	sequence-specific DNA binding
CHR56_RS31235	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS31240	COG4948	Mandelate Racemase Muconate Lactonizing
CHR56_RS31320	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CHR56_RS31345	COG0583	DNA-binding transcription factor activity
CHR56_RS31370	COG2267	carboxylic ester hydrolase activity
CHR56_RS31375	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS31475	COG0446	pyridine nucleotide-disulphide oxidoreductase
CHR56_RS31475	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CHR56_RS31480	COG4311	Sarcosine oxidase, delta subunit
CHR56_RS31485	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CHR56_RS31490	COG4977	sequence-specific DNA binding
CHR56_RS31500	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CHR56_RS31505	COG2218	PFAM glutamate synthase alpha subunit domain protein
CHR56_RS31510	COG0069	glutamate synthase activity
CHR56_RS31525	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CHR56_RS31535	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CHR56_RS31550	COG0840	transmembrane signaling receptor activity
CHR56_RS31555	COG0850	regulation of cytokinetic process
CHR56_RS31560	COG2894	cell division
CHR56_RS31580	COG1278	Cold shock
CHR56_RS31585	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CHR56_RS31595	COG2207	Transcriptional regulator
CHR56_RS31600	COG1280	lysine exporter protein (LysE YggA)
CHR56_RS31605	COG0667	Aldo Keto reductase
CHR56_RS31620	COG0596	Alpha beta hydrolase
CHR56_RS31625	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CHR56_RS31630	COG0745	RESPONSE REGULATOR receiver
CHR56_RS31635	COG2205	protein histidine kinase activity
CHR56_RS31650	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CHR56_RS31655	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS31660	COG2186	Transcriptional regulator
CHR56_RS31665	COG3459	Glycosyltransferase 36 associated
CHR56_RS31685	COG0601	transmembrane transport
CHR56_RS31690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHR56_RS31695	COG0444	Belongs to the ABC transporter superfamily
CHR56_RS31700	COG4172	Belongs to the ABC transporter superfamily
CHR56_RS31720	COG0300	oxidoreductase activity
CHR56_RS31725	COG3321	synthase
CHR56_RS31725	COG0604	alcohol dehydrogenase
CHR56_RS31755	COG1737	Transcriptional regulator
CHR56_RS31780	COG0640	Transcriptional regulator
CHR56_RS31790	COG3842	ATPase activity
CHR56_RS31800	COG0395	ABC-type sugar transport system, permease component
CHR56_RS31810	COG0673	inositol 2-dehydrogenase activity
CHR56_RS31830	COG0583	DNA-binding transcription factor activity
CHR56_RS31835	COG0601	transmembrane transport
CHR56_RS31840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHR56_RS31845	COG4172	Belongs to the ABC transporter superfamily
CHR56_RS31855	COG4166	transmembrane transport
CHR56_RS31860	COG1473	amidohydrolase
CHR56_RS31875	COG3663	DNA glycosylase
CHR56_RS31880	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CHR56_RS31880	COG1017	nitric oxide dioxygenase activity
CHR56_RS31920	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CHR56_RS31940	COG3257	ureidoglycine aminohydrolase activity
CHR56_RS31955	COG4172	Belongs to the ABC transporter superfamily
CHR56_RS31960	COG1921	L-seryl-tRNASec selenium transferase activity
CHR56_RS31975	COG0601	transmembrane transport
CHR56_RS31980	COG0747	negative chemotaxis
CHR56_RS32000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHR56_RS32090	COG3210	domain, Protein
CHR56_RS32105	COG2831	hemolysin activation secretion protein
CHR56_RS32120	COG0352	thiamine-phosphate diphosphorylase activity
CHR56_RS32135	COG1472	Belongs to the glycosyl hydrolase 3 family
CHR56_RS32150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHR56_RS32155	COG0444	Belongs to the ABC transporter superfamily
CHR56_RS32160	COG4608	Belongs to the ABC transporter superfamily
CHR56_RS32180	COG0583	DNA-binding transcription factor activity
CHR56_RS32185	COG3119	arylsulfatase activity
CHR56_RS32225	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS32245	COG3964	amidohydrolase
CHR56_RS32250	COG1595	DNA-templated transcription, initiation
CHR56_RS32255	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CHR56_RS32260	COG4952	isomerase
CHR56_RS32265	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS32265	COG3347	Dehydrogenase
CHR56_RS32270	COG1349	DNA-binding transcription factor activity
CHR56_RS32290	COG1172	Belongs to the binding-protein-dependent transport system permease family
CHR56_RS32320	COG3547	Transposase (IS116 IS110 IS902 family)
CHR56_RS32365	COG1960	acyl-CoA dehydrogenase activity
CHR56_RS32380	COG0583	DNA-binding transcription factor activity
CHR56_RS32390	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CHR56_RS32400	COG1063	alcohol dehydrogenase
CHR56_RS32415	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CHR56_RS32420	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CHR56_RS32425	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CHR56_RS32430	COG2205	protein histidine kinase activity
CHR56_RS32450	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CHR56_RS32460	COG4208	sulfate ABC transporter
CHR56_RS32465	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CHR56_RS32480	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CHR56_RS32485	COG3842	ATPase activity
CHR56_RS32490	COG0395	ABC-type sugar transport system, permease component
CHR56_RS32505	COG0626	cystathionine gamma-synthase activity
CHR56_RS32510	COG1725	Transcriptional regulator
CHR56_RS32515	COG2205	protein histidine kinase activity
CHR56_RS32520	COG0745	RESPONSE REGULATOR receiver
CHR56_RS32575	COG0517	IMP dehydrogenase activity
CHR56_RS32575	COG0516	GMP reductase activity
CHR56_RS32580	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CHR56_RS32585	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CHR56_RS32595	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CHR56_RS32605	COG0071	Belongs to the small heat shock protein (HSP20) family
CHR56_RS32620	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CHR56_RS32625	COG0784	Response regulator, receiver
CHR56_RS32625	COG4191	Histidine kinase
CHR56_RS32670	COG2217	Heavy metal translocating P-type atpase
CHR56_RS32705	COG0640	Transcriptional regulator
CHR56_RS32710	COG3453	Protein conserved in bacteria
CHR56_RS32710	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CHR56_RS32725	COG0583	DNA-binding transcription factor activity
CHR56_RS32745	COG3831	ATPase activity
CHR56_RS32765	COG1573	uracil-dna glycosylase
CHR56_RS32780	COG4191	Histidine kinase
CHR56_RS32780	COG0784	Response regulator, receiver
CHR56_RS32835	COG0183	Belongs to the thiolase family
CHR56_RS32840	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CHR56_RS32850	COG1414	Transcriptional regulator
CHR56_RS32855	COG3511	phospholipase C
CHR56_RS32860	COG1858	cytochrome C peroxidase
CHR56_RS32895	COG4608	Belongs to the ABC transporter superfamily
CHR56_RS32905	COG3831	ATPase activity
CHR56_RS32915	COG2813	Specifically methylates the guanine in position
CHR56_RS32980	COG1126	abc transporter atp-binding protein
CHR56_RS33005	COG4566	intracellular signal transduction
CHR56_RS33010	COG4566	intracellular signal transduction
CHR56_RS33045	COG0628	permease
CHR56_RS33120	COG1486	melibiose metabolic process
CHR56_RS33125	COG4172	Belongs to the ABC transporter superfamily
CHR56_RS33130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHR56_RS33135	COG0601	transmembrane transport
CHR56_RS33140	COG0747	negative chemotaxis
CHR56_RS33145	COG1486	melibiose metabolic process
CHR56_RS33205	COG0671	phosphoesterase, PA-phosphatase related
CHR56_RS33215	COG4566	intracellular signal transduction
CHR56_RS33225	COG3119	arylsulfatase activity
CHR56_RS33255	COG2986	histidine ammonia-lyase
CHR56_RS33285	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CHR56_RS33315	COG0402	S-adenosylhomocysteine deaminase activity
CHR56_RS33320	COG1228	amidohydrolase
CHR56_RS33325	COG2986	histidine ammonia-lyase
CHR56_RS33335	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CHR56_RS33345	COG0484	heat shock protein binding
CHR56_RS33405	COG0730	response to heat
CHR56_RS33415	COG0577	efflux transmembrane transporter activity
CHR56_RS33450	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CHR56_RS33475	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CHR56_RS33475	COG1672	PFAM Archaeal ATPase
CHR56_RS33515	COG5654	RES domain protein
CHR56_RS33525	COG0583	DNA-binding transcription factor activity
CHR56_RS33530	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CHR56_RS33535	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CHR56_RS33540	COG3485	protocatechuate 3,4-dioxygenase
CHR56_RS33545	COG3485	protocatechuate 3,4-dioxygenase
CHR56_RS33555	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS33560	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CHR56_RS33570	COG1126	abc transporter atp-binding protein
CHR56_RS33575	COG0765	amino acid transport
CHR56_RS33580	COG0765	amino acid transport
CHR56_RS33585	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CHR56_RS33595	COG1082	Xylose isomerase domain protein TIM barrel
CHR56_RS33595	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CHR56_RS33610	COG1234	tRNA 3'-trailer cleavage
CHR56_RS33620	COG0596	Alpha beta hydrolase
CHR56_RS33630	COG0438	transferase activity, transferring glycosyl groups
CHR56_RS33660	COG0714	Associated with various cellular activities
CHR56_RS33685	COG1959	2 iron, 2 sulfur cluster binding
CHR56_RS33695	COG5265	(ABC) transporter
CHR56_RS33720	COG4172	Belongs to the ABC transporter superfamily
CHR56_RS33725	COG0747	negative chemotaxis
CHR56_RS33735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHR56_RS33755	COG1132	(ABC) transporter
CHR56_RS33760	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CHR56_RS33760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CHR56_RS33770	COG0477	Major facilitator Superfamily
CHR56_RS33775	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CHR56_RS33780	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CHR56_RS33785	COG1845	cytochrome c oxidase, subunit III
CHR56_RS33790	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CHR56_RS33795	COG3346	SURF1 family
CHR56_RS33800	COG0784	Response regulator, receiver
CHR56_RS33800	COG4191	Histidine kinase
CHR56_RS33815	COG1132	(ABC) transporter
CHR56_RS33820	COG1132	(ABC) transporter
CHR56_RS33845	COG1609	Transcriptional regulator
CHR56_RS33850	COG1879	ABC-type sugar transport system periplasmic component
CHR56_RS33855	COG1129	ABC transporter
CHR56_RS33860	COG1172	Belongs to the binding-protein-dependent transport system permease family
CHR56_RS33895	COG3842	ATPase activity
CHR56_RS33905	COG1176	ABC-type spermidine putrescine transport system, permease component I
CHR56_RS33915	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CHR56_RS33925	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS33935	COG0402	S-adenosylhomocysteine deaminase activity
CHR56_RS33940	COG1079	Belongs to the binding-protein-dependent transport system permease family
CHR56_RS33950	COG3845	ABC transporter
CHR56_RS33970	COG0204	Acyl-transferase
CHR56_RS33970	COG0318	PFAM AMP-dependent synthetase and ligase
CHR56_RS33975	COG4589	Belongs to the CDS family
CHR56_RS33985	COG0484	heat shock protein binding
CHR56_RS34000	COG0625	glutathione transferase activity
CHR56_RS34010	COG4172	Belongs to the ABC transporter superfamily
CHR56_RS34015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHR56_RS34020	COG0601	transmembrane transport
CHR56_RS34025	COG0596	Alpha beta hydrolase
CHR56_RS34090	COG1120	ATPase activity
CHR56_RS34110	COG4774	siderophore transport
CHR56_RS34120	COG1877	trehalose-phosphatase activity
CHR56_RS34140	COG4214	carbohydrate transport
CHR56_RS34150	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS34155	COG5002	protein histidine kinase activity
CHR56_RS34155	COG5000	phosphorelay sensor kinase activity
CHR56_RS34160	COG0745	RESPONSE REGULATOR receiver
CHR56_RS34190	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CHR56_RS34200	COG0583	DNA-binding transcription factor activity
CHR56_RS34205	COG0667	Aldo Keto reductase
CHR56_RS34220	COG3842	ATPase activity
CHR56_RS34225	COG0395	ABC-type sugar transport system, permease component
CHR56_RS34230	COG1175	transmembrane transport
CHR56_RS34235	COG1653	transport
CHR56_RS34265	COG0511	ligase activity, forming carbon-carbon bonds
CHR56_RS34270	COG0439	Biotin carboxylase
CHR56_RS34285	COG1984	allophanate hydrolase subunit 2
CHR56_RS34290	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CHR56_RS34295	COG0436	Aminotransferase
CHR56_RS34305	COG4221	oxidoreductase activity
CHR56_RS34310	COG0765	amino acid transport
CHR56_RS34315	COG0765	amino acid transport
CHR56_RS34320	COG1126	abc transporter atp-binding protein
CHR56_RS34325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHR56_RS34330	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CHR56_RS34345	COG0251	oxidation-reduction process
CHR56_RS34360	COG1172	Belongs to the binding-protein-dependent transport system permease family
CHR56_RS34370	COG1129	ABC transporter
CHR56_RS34375	COG1879	ABC-type sugar transport system periplasmic component
CHR56_RS34385	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CHR56_RS34390	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CHR56_RS34400	COG1116	anion transmembrane transporter activity
CHR56_RS34430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHR56_RS34440	COG1522	sequence-specific DNA binding
CHR56_RS34470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CHR56_RS34475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CHR56_RS34485	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CHR56_RS34505	COG1172	Belongs to the binding-protein-dependent transport system permease family
CHR56_RS34510	COG1129	ABC transporter
CHR56_RS34515	COG2084	Dehydrogenase
CHR56_RS34520	COG3265	gluconokinase activity
CHR56_RS34525	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS34530	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CHR56_RS34535	COG1063	alcohol dehydrogenase
CHR56_RS34540	COG1609	Transcriptional regulator
CHR56_RS34550	COG2304	oxidoreductase activity
CHR56_RS34560	COG0657	acetylesterase activity
CHR56_RS34585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHR56_RS34590	COG0601	transmembrane transport
CHR56_RS34595	COG0747	negative chemotaxis
CHR56_RS34600	COG1024	Enoyl-CoA hydratase
CHR56_RS34610	COG1960	acyl-CoA dehydrogenase activity
CHR56_RS34615	COG0824	Thioesterase
CHR56_RS34615	COG1250	3-hydroxyacyl-CoA dehydrogenase
CHR56_RS34620	COG3246	L-lysine catabolic process to acetate
CHR56_RS34630	COG0583	DNA-binding transcription factor activity
CHR56_RS34645	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHR56_RS34650	COG3300	MHYT domain
CHR56_RS34650	COG5001	Diguanylate cyclase
CHR56_RS34665	COG0436	Aminotransferase
CHR56_RS34680	COG0583	DNA-binding transcription factor activity
CHR56_RS34695	COG0765	amino acid transport
CHR56_RS34700	COG0765	amino acid transport
CHR56_RS34705	COG1126	abc transporter atp-binding protein
CHR56_RS34715	COG1335	isochorismatase
CHR56_RS34720	COG3845	ABC transporter
CHR56_RS34730	COG1335	isochorismatase
CHR56_RS34735	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CHR56_RS34740	COG1079	Belongs to the binding-protein-dependent transport system permease family
CHR56_RS34765	COG1116	anion transmembrane transporter activity
CHR56_RS34770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CHR56_RS34775	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CHR56_RS34780	COG0306	phosphate transporter
CHR56_RS34785	COG1392	Phosphate transport regulator
CHR56_RS34800	COG4603	Belongs to the binding-protein-dependent transport system permease family
CHR56_RS34805	COG3845	ABC transporter
CHR56_RS34820	COG0625	glutathione transferase activity
CHR56_RS34850	COG1070	Carbohydrate kinase
CHR56_RS34855	COG0434	BtpA family
CHR56_RS34860	COG1349	DNA-binding transcription factor activity
CHR56_RS34865	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS34875	COG0395	ABC-type sugar transport system, permease component
CHR56_RS34890	COG2072	flavoprotein involved in K transport
CHR56_RS34930	COG0022	dehydrogenase e1 component
CHR56_RS34940	COG1960	acyl-CoA dehydrogenase activity
CHR56_RS34945	COG0183	Belongs to the thiolase family
CHR56_RS34960	COG1960	acyl-CoA dehydrogenase activity
CHR56_RS34965	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CHR56_RS34975	COG2030	dehydratase
CHR56_RS34990	COG2205	protein histidine kinase activity
CHR56_RS34995	COG0745	RESPONSE REGULATOR receiver
CHR56_RS35020	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CHR56_RS35035	COG3718	enzyme involved in inositol metabolism
CHR56_RS35040	COG4608	Belongs to the ABC transporter superfamily
CHR56_RS35045	COG0444	Belongs to the ABC transporter superfamily
CHR56_RS35050	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHR56_RS35055	COG0601	transmembrane transport
CHR56_RS35060	COG0747	negative chemotaxis
CHR56_RS35065	COG1609	Transcriptional regulator
CHR56_RS35075	COG3547	Transposase (IS116 IS110 IS902 family)
CHR56_RS35095	COG0006	proline dipeptidase activity
CHR56_RS35110	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CHR56_RS35115	COG3842	ATPase activity
CHR56_RS35125	COG0395	ABC-type sugar transport system, permease component
CHR56_RS35130	COG1175	transmembrane transport
CHR56_RS35135	COG1653	transport
CHR56_RS35145	COG1609	Transcriptional regulator
CHR56_RS35150	COG3250	beta-galactosidase activity
CHR56_RS35160	COG1175	transmembrane transport
CHR56_RS35165	COG0395	ABC-type sugar transport system, permease component
CHR56_RS35195	COG3842	ATPase activity
CHR56_RS35200	COG1177	transmembrane transport
CHR56_RS35205	COG1176	ABC-type spermidine putrescine transport system, permease component I
CHR56_RS35220	COG1012	belongs to the aldehyde dehydrogenase family
CHR56_RS35225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CHR56_RS35235	COG2267	carboxylic ester hydrolase activity
CHR56_RS35255	COG4521	taurine ABC transporter
CHR56_RS35265	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CHR56_RS35300	COG1395	domain, Protein
CHR56_RS35330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CHR56_RS35340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHR56_RS35345	COG1126	abc transporter atp-binding protein
CHR56_RS35355	COG1473	amidohydrolase
CHR56_RS35360	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CHR56_RS35365	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CHR56_RS35375	COG3668	Plasmid stabilization system
CHR56_RS35385	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CHR56_RS35390	COG2323	membrane
CHR56_RS35395	COG2186	Transcriptional regulator
CHR56_RS35405	COG4608	Belongs to the ABC transporter superfamily
CHR56_RS35410	COG0444	Belongs to the ABC transporter superfamily
CHR56_RS35415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHR56_RS35420	COG0601	transmembrane transport
CHR56_RS35425	COG0747	negative chemotaxis
CHR56_RS35430	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CHR56_RS35440	COG1454	alcohol dehydrogenase
CHR56_RS35445	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CHR56_RS35460	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CHR56_RS35465	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CHR56_RS35470	COG1116	anion transmembrane transporter activity
CHR56_RS35495	COG1129	ABC transporter
CHR56_RS35500	COG1172	Belongs to the binding-protein-dependent transport system permease family
CHR56_RS35505	COG1172	Belongs to the binding-protein-dependent transport system permease family
CHR56_RS35510	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CHR56_RS35525	COG0395	ABC-type sugar transport system, permease component
CHR56_RS35540	COG3842	ATPase activity
CHR56_RS35600	COG0488	(ABC) transporter
CHR56_RS35635	COG1802	Transcriptional regulator
CHR56_RS35680	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CHR56_RS35685	COG0579	oxidoreductase
CHR56_RS35695	COG2274	protein secretion by the type I secretion system
CHR56_RS35705	COG0523	cobalamin synthesis protein
CHR56_RS35715	COG0523	cobalamin synthesis protein
CHR56_RS35735	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CHR56_RS35740	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CHR56_RS35755	COG0673	inositol 2-dehydrogenase activity
CHR56_RS35765	COG2197	response regulator
CHR56_RS35780	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CHR56_RS35810	COG1215	transferase activity, transferring glycosyl groups
CHR56_RS35820	COG0297	glycogen (starch) synthase activity
CHR56_RS35830	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CHR56_RS35845	COG3485	protocatechuate 3,4-dioxygenase
CHR56_RS35870	COG1137	ATPase activity
CHR56_RS35885	COG3485	protocatechuate 3,4-dioxygenase
CHR56_RS35890	COG0583	DNA-binding transcription factor activity
CHR56_RS35895	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CHR56_RS35900	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CHR56_RS35905	COG1609	Transcriptional regulator
CHR56_RS35910	COG1172	Belongs to the binding-protein-dependent transport system permease family
CHR56_RS35915	COG1129	ABC transporter
CHR56_RS35920	COG1609	Transcriptional regulator
CHR56_RS35930	COG5489	Protein of unknown function (DUF736)
CHR56_RS35935	COG3831	ATPase activity
CHR56_RS35940	COG3916	Acyl-homoserine-lactone synthase
CHR56_RS35945	COG1192	Involved in chromosome partitioning
CHR56_RS35950	COG1475	DNA binding
CHR56_RS35970	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CHR56_RS36010	COG1609	Transcriptional regulator
CHR56_RS36015	COG1653	transport
CHR56_RS36020	COG1175	transmembrane transport
CHR56_RS36025	COG0395	ABC-type sugar transport system, permease component
CHR56_RS36030	COG1621	beta-fructofuranosidase activity
CHR56_RS36035	COG3842	ATPase activity
CHR56_RS36055	COG1609	Transcriptional regulator
CHR56_RS36080	COG0673	inositol 2-dehydrogenase activity
CHR56_RS36125	COG1396	sequence-specific DNA binding
CHR56_RS36130	COG2223	nitrite transmembrane transporter activity
CHR56_RS36140	COG1464	Belongs to the NlpA lipoprotein family
CHR56_RS36150	COG2011	ABC-type metal ion transport system permease component
CHR56_RS36165	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CHR56_RS36165	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CHR56_RS36180	COG0673	inositol 2-dehydrogenase activity
CHR56_RS36185	COG0346	lactoylglutathione lyase activity
CHR56_RS36210	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CHR56_RS36240	COG0395	ABC-type sugar transport system, permease component
CHR56_RS36250	COG0667	Aldo Keto reductase
CHR56_RS36260	COG1294	oxidase, subunit
CHR56_RS36265	COG1271	oxidase subunit
CHR56_RS36270	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CHR56_RS36275	COG4988	ABC transporter
CHR56_RS36290	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CHR56_RS36300	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CHR56_RS36310	COG1175	transmembrane transport
CHR56_RS36325	COG0584	glycerophosphoryl diester phosphodiesterase
CHR56_RS36330	COG1609	Transcriptional regulator
CHR56_RS36340	COG3706	GGDEF domain
CHR56_RS36365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHR56_RS36375	COG0747	negative chemotaxis
CHR56_RS36385	COG1172	Belongs to the binding-protein-dependent transport system permease family
CHR56_RS36390	COG1129	ABC transporter
CHR56_RS36395	COG4213	ABC transporter substrate-binding protein
CHR56_RS36425	COG1609	Transcriptional regulator
CHR56_RS36430	COG0673	inositol 2-dehydrogenase activity
CHR56_RS36445	COG1175	transmembrane transport
CHR56_RS36450	COG0395	ABC-type sugar transport system, permease component
CHR56_RS36460	COG1609	Transcriptional regulator
CHR56_RS36465	COG1879	ABC-type sugar transport system periplasmic component
CHR56_RS36470	COG1129	ABC transporter
CHR56_RS36475	COG1172	Belongs to the binding-protein-dependent transport system permease family
CHR56_RS36525	COG1192	Involved in chromosome partitioning
CHR56_RS36530	COG3916	Acyl-homoserine-lactone synthase
CHR56_RS36535	COG4962	Type ii secretion system protein e
CHR56_RS36540	COG3838	Conjugal transfer protein Trbc
CHR56_RS36545	COG5268	conjugation
CHR56_RS36550	COG3451	type IV secretory pathway VirB4
CHR56_RS36555	COG5314	conjugation
CHR56_RS36565	COG3846	protein secretion by the type IV secretion system
CHR56_RS36570	COG3701	Conjugal transfer protein
CHR56_RS36575	COG3504	Conjugal transfer protein
CHR56_RS36585	COG2948	multi-organism process
CHR56_RS36590	COG2771	luxR family
CHR56_RS36620	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CHR56_RS36625	COG4959	Type IV secretory pathway protease TraF
CHR56_RS36630	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CHR56_RS36645	COG3505	Type IV secretory pathway VirD4
CHR56_RS36660	COG3831	ATPase activity
CHR56_RS36670	COG5489	Protein of unknown function (DUF736)
CHR56_RS36675	COG4227	nucleotidyltransferase activity
CHR56_RS36690	COG1475	DNA binding
CHR56_RS36700	COG2188	Transcriptional regulator
CHR56_RS36705	COG2971	BadF BadG BcrA BcrD
CHR56_RS36725	COG1082	Xylose isomerase domain protein TIM barrel
CHR56_RS36730	COG1178	ABC-type Fe3 transport system permease component
CHR56_RS36735	COG3842	ATPase activity
CHR56_RS36740	COG1840	ABC-type Fe3 transport system, periplasmic component
CHR56_RS36745	COG1940	carbohydrate kinase activity
CHR56_RS36765	COG0395	ABC-type sugar transport system, permease component
CHR56_RS36795	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CHR56_RS36805	COG0584	glycerophosphoryl diester phosphodiesterase
CHR56_RS36845	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CHR56_RS36850	COG0251	oxidation-reduction process
CHR56_RS36875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CHR56_RS36900	COG3328	transposase activity
CHR56_RS36955	COG0154	amidase activity
CHR56_RS37080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CHR56_RS37085	COG2963	transposase activity
CHR56_RS37090	COG3436	PFAM IS66 Orf2 family protein
CHR56_RS37095	COG4372	Transposase
CHR56_RS37100	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CHR56_RS37110	COG2433	Pfam Transposase IS66
CHR56_RS37115	COG3436	PFAM IS66 Orf2 family protein
CHR56_RS37120	COG2963	transposase activity
CHR56_RS37130	COG5554	nitrogen fixation
CHR56_RS37135	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CHR56_RS37160	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CHR56_RS37165	COG2086	electron transfer activity
CHR56_RS37235	COG1454	alcohol dehydrogenase
CHR56_RS37245	COG3243	poly(R)-hydroxyalkanoic acid synthase
CHR56_RS37275	COG1192	Involved in chromosome partitioning
CHR56_RS37300	COG1454	alcohol dehydrogenase
CHR56_RS37310	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CHR56_RS37315	COG0563	adenylate kinase activity
CHR56_RS37350	COG1129	ABC transporter
CHR56_RS37360	COG0559	Belongs to the binding-protein-dependent transport system permease family
CHR56_RS37370	COG1414	Transcriptional regulator
CHR56_RS37380	COG1454	alcohol dehydrogenase
CHR56_RS37390	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CHR56_RS37405	COG0789	Transcriptional regulator
CHR56_RS37415	COG3831	ATPase activity
CHR56_RS37455	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
CHR56_RS37460	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
CHR56_RS37465	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
CHR56_RS37470	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
CHR56_RS37480	COG3383	formate dehydrogenase (NAD+) activity
CHR56_RS37485	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CHR56_RS37520	COG3547	Transposase (IS116 IS110 IS902 family)
CHR56_RS37615	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CHR56_RS37645	COG3161	chorismate lyase activity
CHR56_RS37650	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CHR56_RS37665	COG2022	thiamine diphosphate biosynthetic process
CHR56_RS37675	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CHR56_RS37680	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS37710	COG3293	Transposase
CHR56_RS37740	COG1181	Belongs to the D-alanine--D-alanine ligase family
CHR56_RS37790	COG1917	Cupin 2, conserved barrel domain protein
CHR56_RS37790	COG1396	sequence-specific DNA binding
CHR56_RS37795	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CHR56_RS37830	COG3485	protocatechuate 3,4-dioxygenase
CHR56_RS37840	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CHR56_RS37875	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CHR56_RS37880	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CHR56_RS37895	COG2022	thiamine diphosphate biosynthetic process
CHR56_RS37900	COG1522	sequence-specific DNA binding
CHR56_RS37930	COG2113	Glycine betaine
CHR56_RS37935	COG4176	ABC-type proline glycine betaine transport system permease component
CHR56_RS37965	COG1278	Cold shock
CHR56_RS37980	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CHR56_RS38005	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CHR56_RS38060	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CHR56_RS38090	COG1278	Cold shock
CHR56_RS38100	COG0640	Transcriptional regulator
CHR56_RS38105	COG1475	DNA binding
CHR56_RS38110	COG1192	Involved in chromosome partitioning
CHR56_RS38115	COG3916	Acyl-homoserine-lactone synthase
CHR56_RS38120	COG4962	Type ii secretion system protein e
CHR56_RS38125	COG3838	Conjugal transfer protein Trbc
CHR56_RS38130	COG5268	conjugation
CHR56_RS38135	COG3451	type IV secretory pathway VirB4
CHR56_RS38140	COG5314	conjugation
CHR56_RS38160	COG3504	Conjugal transfer protein
CHR56_RS38190	COG2801	Transposase and inactivated derivatives
CHR56_RS38195	COG2963	transposase activity
CHR56_RS38215	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS38220	COG2814	Major facilitator Superfamily
CHR56_RS38230	COG0179	Fumarylacetoacetate (FAA) hydrolase
CHR56_RS38235	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CHR56_RS38240	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CHR56_RS38250	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CHR56_RS38255	COG1609	Transcriptional regulator
CHR56_RS38270	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CHR56_RS38275	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS38290	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CHR56_RS38300	COG0583	DNA-binding transcription factor activity
CHR56_RS38305	COG0840	transmembrane signaling receptor activity
CHR56_RS38350	COG1073	alpha beta
CHR56_RS38370	COG1881	PFAM PEBP family protein
CHR56_RS38445	COG4372	Transposase
CHR56_RS38450	COG3344	reverse transcriptase
CHR56_RS38485	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CHR56_RS38515	COG1192	Involved in chromosome partitioning
CHR56_RS38520	COG1475	DNA binding
CHR56_RS38525	COG0640	Transcriptional regulator
CHR56_RS38610	COG0776	regulation of translation
CHR56_RS38615	COG3831	ATPase activity
CHR56_RS38645	COG0741	lytic transglycosylase activity
CHR56_RS38660	COG3451	type IV secretory pathway VirB4
CHR56_RS38665	COG0741	lytic transglycosylase activity
CHR56_RS38695	COG2948	multi-organism process
CHR56_RS38700	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
CHR56_RS38765	COG1192	Involved in chromosome partitioning
CHR56_RS38800	COG3842	ATPase activity
CHR56_RS38810	COG0395	ABC-type sugar transport system, permease component
CHR56_RS38815	COG1175	transmembrane transport
CHR56_RS38830	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CHR56_RS38835	COG4211	Belongs to the binding-protein-dependent transport system permease family
CHR56_RS38840	COG1172	Belongs to the binding-protein-dependent transport system permease family
CHR56_RS38845	COG1129	ABC transporter
CHR56_RS38895	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CHR56_RS38900	COG0251	oxidation-reduction process
CHR56_RS38920	COG0460	homoserine dehydrogenase
CHR56_RS38925	COG1012	belongs to the aldehyde dehydrogenase family
CHR56_RS38935	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CHR56_RS38960	COG0765	amino acid transport
CHR56_RS38965	COG1126	abc transporter atp-binding protein
CHR56_RS38980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHR56_RS39010	COG2801	Transposase and inactivated derivatives
CHR56_RS39015	COG2963	transposase activity
CHR56_RS39035	COG1028	Short-chain dehydrogenase reductase Sdr
CHR56_RS39075	COG3750	Belongs to the UPF0335 family
CHR56_RS39180	COG2197	response regulator
CHR56_RS39185	COG0463	Glycosyl transferase, family 2
CHR56_RS39185	COG1216	Glycosyl transferase, family 2