locus-tag	class	description
KIM5_RS00010	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KIM5_RS00015	COG0424	maF-like protein
KIM5_RS00020	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KIM5_RS00025	COG0237	dephospho-CoA kinase activity
KIM5_RS00030	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KIM5_RS00035	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
KIM5_RS00050	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
KIM5_RS00080	COG0179	Fumarylacetoacetate (FAA) hydrolase
KIM5_RS00100	COG0135	phosphoribosylanthranilate isomerase activity
KIM5_RS00105	COG0133	tryptophan synthase activity
KIM5_RS00110	COG0159	tryptophan synthase activity
KIM5_RS00115	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KIM5_RS00120	COG0285	dihydrofolate synthase activity
KIM5_RS00130	COG1074	ATP-dependent DNA helicase activity
KIM5_RS00135	COG2887	Belongs to the helicase family. UvrD subfamily
KIM5_RS00140	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KIM5_RS00145	COG0802	atpase or kinase
KIM5_RS00150	COG2205	protein histidine kinase activity
KIM5_RS00155	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KIM5_RS00160	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KIM5_RS00165	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
KIM5_RS00165	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KIM5_RS00175	COG0642	Histidine kinase
KIM5_RS00180	COG0745	RESPONSE REGULATOR receiver
KIM5_RS00185	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KIM5_RS00200	COG1072	(Pantothenic acid kinase))
KIM5_RS00205	COG0140	phosphoribosyl-ATP diphosphatase activity
KIM5_RS00210	COG0107	imidazoleglycerol-phosphate synthase activity
KIM5_RS00215	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KIM5_RS00230	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KIM5_RS00240	COG0131	Imidazoleglycerol-phosphate dehydratase
KIM5_RS00245	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KIM5_RS00250	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KIM5_RS00260	COG2124	cytochrome p450
KIM5_RS00265	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KIM5_RS00280	COG4948	Mandelate Racemase Muconate Lactonizing
KIM5_RS00295	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
KIM5_RS00305	COG1643	Atp-dependent helicase
KIM5_RS00350	COG2197	response regulator
KIM5_RS00360	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KIM5_RS00365	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KIM5_RS00370	COG1215	transferase activity, transferring glycosyl groups
KIM5_RS00390	COG1609	Transcriptional regulator
KIM5_RS00400	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KIM5_RS00405	COG0673	inositol 2-dehydrogenase activity
KIM5_RS00420	COG0673	inositol 2-dehydrogenase activity
KIM5_RS00425	COG1309	transcriptional regulator
KIM5_RS00435	COG1175	transmembrane transport
KIM5_RS00440	COG0395	ABC-type sugar transport system, permease component
KIM5_RS00450	COG3842	ATPase activity
KIM5_RS00470	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KIM5_RS00505	COG0246	Mannitol dehydrogenase
KIM5_RS00510	COG1904	glucuronate isomerase
KIM5_RS00515	COG2900	Belongs to the SlyX family
KIM5_RS00520	COG1012	belongs to the aldehyde dehydrogenase family
KIM5_RS00525	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KIM5_RS00545	COG0539	negative regulation of cytoplasmic translation
KIM5_RS00550	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KIM5_RS00600	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KIM5_RS00610	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KIM5_RS00615	COG2813	Specifically methylates the guanine in position
KIM5_RS00620	COG1185	polyribonucleotide nucleotidyltransferase activity
KIM5_RS00625	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KIM5_RS00630	COG0596	Alpha beta hydrolase
KIM5_RS00635	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KIM5_RS00640	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KIM5_RS00645	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KIM5_RS00660	COG0779	Required for maturation of 30S ribosomal subunits
KIM5_RS00665	COG2814	Major facilitator Superfamily
KIM5_RS00680	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KIM5_RS00685	COG2258	MOSC domain
KIM5_RS00690	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KIM5_RS00695	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KIM5_RS00710	COG2816	NAD+ diphosphatase activity
KIM5_RS00715	COG2378	regulation of single-species biofilm formation
KIM5_RS00730	COG1605	Chorismate mutase
KIM5_RS00730	COG0077	Prephenate dehydratase
KIM5_RS00735	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
KIM5_RS00740	COG3474	cytochrome
KIM5_RS00745	COG0679	Auxin Efflux Carrier
KIM5_RS00750	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KIM5_RS00775	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KIM5_RS00780	COG1396	sequence-specific DNA binding
KIM5_RS00790	COG0484	heat shock protein binding
KIM5_RS00795	COG0443	Heat shock 70 kDa protein
KIM5_RS00800	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KIM5_RS00815	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KIM5_RS00820	COG5001	Diguanylate cyclase
KIM5_RS00820	COG3300	MHYT domain
KIM5_RS00830	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KIM5_RS00830	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KIM5_RS00835	COG1674	ftsk spoiiie
KIM5_RS00840	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
KIM5_RS00845	COG3454	Phosphonate metabolism
KIM5_RS00850	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
KIM5_RS00860	COG3639	organic phosphonate transmembrane transporter activity
KIM5_RS00865	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
KIM5_RS00870	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KIM5_RS00880	COG4778	phosphonate C-P lyase system protein PhnL
KIM5_RS00885	COG4107	phosphonate C-P lyase system protein PhnK
KIM5_RS00890	COG3627	carbon phosphorus lyase activity
KIM5_RS00895	COG3626	phosphonate metabolism
KIM5_RS00900	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
KIM5_RS00905	COG3624	Phosphonate C-P lyase system protein PhnG
KIM5_RS00910	COG2188	Transcriptional regulator
KIM5_RS00915	COG0588	phosphoglycerate mutase activity
KIM5_RS00920	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KIM5_RS00925	COG1132	(ABC) transporter
KIM5_RS00930	COG0837	glucose binding
KIM5_RS00935	COG1803	Methylglyoxal synthase
KIM5_RS00940	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
KIM5_RS00945	COG4166	transmembrane transport
KIM5_RS00950	COG4174	ABC transporter (Permease)
KIM5_RS00955	COG4239	(ABC) transporter, permease
KIM5_RS00960	COG4172	Belongs to the ABC transporter superfamily
KIM5_RS00965	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KIM5_RS00975	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KIM5_RS00990	COG3609	addiction module antidote protein, CC2985 family
KIM5_RS01010	COG1744	ABC transporter substrate-binding protein PnrA-like
KIM5_RS01015	COG3845	ABC transporter
KIM5_RS01020	COG1079	Belongs to the binding-protein-dependent transport system permease family
KIM5_RS01025	COG1079	Belongs to the binding-protein-dependent transport system permease family
KIM5_RS01035	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KIM5_RS01040	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KIM5_RS01045	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KIM5_RS01055	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KIM5_RS01060	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KIM5_RS01065	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
KIM5_RS01100	COG4964	Belongs to the GSP D family
KIM5_RS01130	COG1280	lysine exporter protein (LysE YggA)
KIM5_RS01140	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KIM5_RS01155	COG0154	amidase activity
KIM5_RS01160	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KIM5_RS01185	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KIM5_RS01195	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KIM5_RS01205	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KIM5_RS01270	COG0481	GTPase activity
KIM5_RS01275	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KIM5_RS01280	COG1396	sequence-specific DNA binding
KIM5_RS01300	COG2137	regulation of response to DNA damage stimulus
KIM5_RS01330	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KIM5_RS01335	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KIM5_RS01340	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KIM5_RS01345	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KIM5_RS01350	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KIM5_RS01350	COG0072	phenylalanine-tRNA ligase activity
KIM5_RS01360	COG0667	Aldo Keto reductase
KIM5_RS01370	COG3685	Protein conserved in bacteria
KIM5_RS01420	COG1570	exodeoxyribonuclease VII activity
KIM5_RS01425	COG2249	NAD(P)H dehydrogenase (quinone) activity
KIM5_RS01430	COG1846	Transcriptional regulator
KIM5_RS01435	COG0697	spore germination
KIM5_RS01440	COG2309	aminopeptidase activity
KIM5_RS01445	COG0625	glutathione transferase activity
KIM5_RS01455	COG0442	prolyl-tRNA aminoacylation
KIM5_RS01460	COG1393	Belongs to the ArsC family
KIM5_RS01470	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KIM5_RS01475	COG4221	oxidoreductase activity
KIM5_RS01480	COG1028	Short-chain dehydrogenase reductase Sdr
KIM5_RS01490	COG0583	DNA-binding transcription factor activity
KIM5_RS01495	COG2207	Transcriptional regulator
KIM5_RS01500	COG1881	PFAM PEBP family protein
KIM5_RS01505	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KIM5_RS01520	COG0519	Catalyzes the synthesis of GMP from XMP
KIM5_RS01520	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KIM5_RS01565	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KIM5_RS01575	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KIM5_RS01585	COG1968	undecaprenyl-diphosphatase activity
KIM5_RS01605	COG0284	orotidine-5'-phosphate decarboxylase activity
KIM5_RS01615	COG3963	phosphatidate phosphatase activity
KIM5_RS01630	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KIM5_RS01635	COG0792	nuclease activity
KIM5_RS01645	COG0189	ligase activity
KIM5_RS01665	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KIM5_RS01675	COG0697	spore germination
KIM5_RS01680	COG1522	sequence-specific DNA binding
KIM5_RS01685	COG0456	acetyltransferase
KIM5_RS01690	COG0756	dUTP diphosphatase activity
KIM5_RS01695	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KIM5_RS01745	COG2807	transmembrane transport
KIM5_RS01760	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KIM5_RS01770	COG2814	Major facilitator Superfamily
KIM5_RS01790	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KIM5_RS01810	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KIM5_RS01815	COG2986	histidine ammonia-lyase
KIM5_RS01820	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KIM5_RS01825	COG2226	methyltransferase
KIM5_RS01830	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KIM5_RS01835	COG1024	Enoyl-CoA hydratase
KIM5_RS01840	COG0268	Binds directly to 16S ribosomal RNA
KIM5_RS01845	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KIM5_RS01855	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KIM5_RS01860	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KIM5_RS01870	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KIM5_RS01875	COG1420	regulation of RNA biosynthetic process
KIM5_RS01880	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KIM5_RS01890	COG0071	Belongs to the small heat shock protein (HSP20) family
KIM5_RS01900	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KIM5_RS01905	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KIM5_RS01910	COG1396	sequence-specific DNA binding
KIM5_RS01915	COG0815	Transfers the fatty acyl group on membrane lipoproteins
KIM5_RS01920	COG1253	flavin adenine dinucleotide binding
KIM5_RS01925	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KIM5_RS01930	COG1702	phosphate starvation-inducible protein PhoH
KIM5_RS01935	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KIM5_RS01960	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KIM5_RS01970	COG0180	Tryptophanyl-tRNA synthetase
KIM5_RS02000	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KIM5_RS02005	COG0281	malic enzyme
KIM5_RS02005	COG0280	phosphate acetyltransferase
KIM5_RS02025	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KIM5_RS02030	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KIM5_RS02035	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KIM5_RS02035	COG0116	Belongs to the methyltransferase superfamily
KIM5_RS02055	COG0776	regulation of translation
KIM5_RS02070	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
KIM5_RS02075	COG1137	ATPase activity
KIM5_RS02085	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KIM5_RS02090	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KIM5_RS02095	COG0840	transmembrane signaling receptor activity
KIM5_RS02100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KIM5_RS02115	COG0242	peptide deformylase activity
KIM5_RS02130	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KIM5_RS02135	COG0101	tRNA pseudouridine synthase activity
KIM5_RS02145	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KIM5_RS02150	COG2171	N-acyltransferase activity
KIM5_RS02170	COG1032	radical SAM domain protein
KIM5_RS02175	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KIM5_RS02175	COG2169	Transcriptional regulator
KIM5_RS02185	COG1304	FMN binding
KIM5_RS02195	COG0640	Transcriptional regulator
KIM5_RS02200	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KIM5_RS02220	COG5484	DNA packaging
KIM5_RS02230	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
KIM5_RS02235	COG3920	Histidine kinase
KIM5_RS02250	COG1278	Cold shock
KIM5_RS02255	COG0218	Necessary for normal cell division and for the maintenance of normal septation
KIM5_RS02260	COG0706	membrane insertase activity
KIM5_RS02265	COG0594	ribonuclease P activity
KIM5_RS02270	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KIM5_RS02275	COG0840	transmembrane signaling receptor activity
KIM5_RS02290	COG0583	DNA-binding transcription factor activity
KIM5_RS02340	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KIM5_RS02345	COG0667	Aldo Keto reductase
KIM5_RS02355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KIM5_RS02360	COG3938	Belongs to the proline racemase family
KIM5_RS02380	COG5001	Diguanylate cyclase
KIM5_RS02380	COG3300	MHYT domain
KIM5_RS02385	COG2267	carboxylic ester hydrolase activity
KIM5_RS02390	COG0604	alcohol dehydrogenase
KIM5_RS02400	COG3546	catalase activity
KIM5_RS02440	COG1072	(Pantothenic acid kinase))
KIM5_RS02445	COG0418	dihydroorotase activity
KIM5_RS02475	COG1309	transcriptional regulator
KIM5_RS02480	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KIM5_RS02495	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
KIM5_RS02500	COG0166	Belongs to the GPI family
KIM5_RS02515	COG0318	PFAM AMP-dependent synthetase and ligase
KIM5_RS02530	COG1174	glycine betaine transport
KIM5_RS02535	COG1125	glycine betaine transport
KIM5_RS02540	COG1174	glycine betaine transport
KIM5_RS02545	COG1732	Glycine betaine
KIM5_RS02555	COG0583	DNA-binding transcription factor activity
KIM5_RS02560	COG3142	Participates in the control of copper homeostasis
KIM5_RS02565	COG1063	alcohol dehydrogenase
KIM5_RS02570	COG1172	Belongs to the binding-protein-dependent transport system permease family
KIM5_RS02595	COG2721	sulfolactate sulfo-lyase activity
KIM5_RS02610	COG4178	(ABC) transporter
KIM5_RS02615	COG0477	Major facilitator Superfamily
KIM5_RS02660	COG2326	polyphosphate kinase activity
KIM5_RS02665	COG5002	protein histidine kinase activity
KIM5_RS02670	COG2852	Protein conserved in bacteria
KIM5_RS02675	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KIM5_RS02680	COG0573	inorganic phosphate transmembrane transporter activity
KIM5_RS02690	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KIM5_RS02695	COG0704	Plays a role in the regulation of phosphate uptake
KIM5_RS02700	COG0745	RESPONSE REGULATOR receiver
KIM5_RS02715	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KIM5_RS02720	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KIM5_RS02725	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KIM5_RS02730	COG2967	ApaG domain
KIM5_RS02740	COG0717	Belongs to the dCTP deaminase family
KIM5_RS02785	COG0840	transmembrane signaling receptor activity
KIM5_RS02785	COG2972	Histidine kinase
KIM5_RS02790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KIM5_RS02825	COG0167	dihydroorotate dehydrogenase activity
KIM5_RS02830	COG0534	Mate efflux family protein
KIM5_RS02855	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KIM5_RS02860	COG1959	2 iron, 2 sulfur cluster binding
KIM5_RS02870	COG1201	RNA secondary structure unwinding
KIM5_RS02895	COG0730	response to heat
KIM5_RS02910	COG1960	acyl-CoA dehydrogenase activity
KIM5_RS02915	COG0183	Belongs to the thiolase family
KIM5_RS02920	COG1024	Enoyl-CoA hydratase
KIM5_RS02920	COG1250	3-hydroxyacyl-CoA dehydrogenase
KIM5_RS02930	COG1278	Cold shock
KIM5_RS02960	COG2198	Histidine kinase
KIM5_RS02960	COG0784	Response regulator, receiver
KIM5_RS02960	COG2205	protein histidine kinase activity
KIM5_RS02965	COG1970	mechanosensitive ion channel activity
KIM5_RS02970	COG0436	Aminotransferase
KIM5_RS02985	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KIM5_RS03025	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KIM5_RS03035	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KIM5_RS03040	COG5328	Belongs to the UPF0262 family
KIM5_RS03045	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KIM5_RS03050	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KIM5_RS03055	COG0424	maF-like protein
KIM5_RS03060	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
KIM5_RS03070	COG1216	Glycosyl transferase, family 2
KIM5_RS03090	COG0251	oxidation-reduction process
KIM5_RS03095	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KIM5_RS03105	COG0444	Belongs to the ABC transporter superfamily
KIM5_RS03110	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KIM5_RS03125	COG2186	Transcriptional regulator
KIM5_RS03130	COG1609	Transcriptional regulator
KIM5_RS03145	COG1172	Belongs to the binding-protein-dependent transport system permease family
KIM5_RS03155	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KIM5_RS03160	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KIM5_RS03190	COG0346	lactoylglutathione lyase activity
KIM5_RS03195	COG4251	negative regulation of phosphorylation
KIM5_RS03205	COG4251	negative regulation of phosphorylation
KIM5_RS03215	COG2197	response regulator
KIM5_RS03225	COG5000	phosphorelay sensor kinase activity
KIM5_RS03240	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KIM5_RS03240	COG4651	solute:proton antiporter activity
KIM5_RS03250	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KIM5_RS03255	COG0840	transmembrane signaling receptor activity
KIM5_RS03265	COG0745	RESPONSE REGULATOR receiver
KIM5_RS03270	COG2198	Histidine kinase
KIM5_RS03270	COG0643	Histidine kinase
KIM5_RS03275	COG0835	chemotaxis
KIM5_RS03280	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KIM5_RS03285	COG2201	protein-glutamate methylesterase activity
KIM5_RS03290	COG0745	RESPONSE REGULATOR receiver
KIM5_RS03295	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
KIM5_RS03305	COG1766	The M ring may be actively involved in energy transduction
KIM5_RS03310	COG2771	luxR family
KIM5_RS03325	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KIM5_RS03330	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KIM5_RS03335	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KIM5_RS03340	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KIM5_RS03345	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KIM5_RS03350	COG4786	Flagellar basal body rod
KIM5_RS03355	COG1157	protein secretion by the type III secretion system
KIM5_RS03365	COG1815	bacterial-type flagellum-dependent cell motility
KIM5_RS03370	COG1558	bacterial-type flagellum-dependent cell motility
KIM5_RS03375	COG1677	Flagellar hook-basal body complex protein FliE
KIM5_RS03380	COG4786	Flagellar basal body rod
KIM5_RS03385	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
KIM5_RS03390	COG1706	bacterial-type flagellum-dependent cell motility
KIM5_RS03400	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
KIM5_RS03410	COG1338	Plays a role in the flagellum-specific transport system
KIM5_RS03430	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KIM5_RS03435	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KIM5_RS03445	COG1360	Flagellar Motor Protein
KIM5_RS03470	COG1749	Flagellar hook protein flgE
KIM5_RS03475	COG1256	bacterial-type flagellum assembly
KIM5_RS03490	COG5443	negative regulation of bacterial-type flagellum assembly
KIM5_RS03505	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KIM5_RS03510	COG1684	flagellar biosynthetic protein fliR
KIM5_RS03535	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
KIM5_RS03545	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KIM5_RS03550	COG1609	Transcriptional regulator
KIM5_RS03555	COG1653	transport
KIM5_RS03560	COG1175	transmembrane transport
KIM5_RS03565	COG0395	ABC-type sugar transport system, permease component
KIM5_RS03570	COG0366	Alpha amylase catalytic
KIM5_RS03575	COG3842	ATPase activity
KIM5_RS03585	COG0129	dihydroxy-acid dehydratase activity
KIM5_RS03590	COG0363	glucosamine-6-phosphate deaminase activity
KIM5_RS03595	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KIM5_RS03600	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KIM5_RS03610	COG2081	HI0933 family
KIM5_RS03615	COG0840	transmembrane signaling receptor activity
KIM5_RS03615	COG2972	Histidine kinase
KIM5_RS03620	COG0840	transmembrane signaling receptor activity
KIM5_RS03640	COG2224	Isocitrate lyase
KIM5_RS03650	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KIM5_RS03655	COG3842	ATPase activity
KIM5_RS03660	COG1176	ABC-type spermidine putrescine transport system, permease component I
KIM5_RS03665	COG1177	transmembrane transport
KIM5_RS03675	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KIM5_RS03680	COG2205	protein histidine kinase activity
KIM5_RS03775	COG3179	chitinase
KIM5_RS04220	COG4269	membrane
KIM5_RS04230	COG1959	2 iron, 2 sulfur cluster binding
KIM5_RS04235	COG0747	negative chemotaxis
KIM5_RS04240	COG0601	transmembrane transport
KIM5_RS04245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KIM5_RS04250	COG0444	Belongs to the ABC transporter superfamily
KIM5_RS04255	COG4608	Belongs to the ABC transporter superfamily
KIM5_RS04260	COG3265	gluconokinase activity
KIM5_RS04265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KIM5_RS04270	COG1755	Isoprenylcysteine carboxyl methyltransferase
KIM5_RS04285	COG1595	DNA-templated transcription, initiation
KIM5_RS04310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KIM5_RS04350	COG0110	maltose O-acetyltransferase activity
KIM5_RS04395	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KIM5_RS04425	COG4372	Transposase
KIM5_RS04435	COG2963	transposase activity
KIM5_RS04475	COG2076	Multidrug Resistance protein
KIM5_RS04490	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KIM5_RS04495	COG0463	Glycosyl transferase, family 2
KIM5_RS04500	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KIM5_RS04505	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KIM5_RS04575	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KIM5_RS04585	COG0477	Major facilitator Superfamily
KIM5_RS04620	COG0583	DNA-binding transcription factor activity
KIM5_RS04650	COG0306	phosphate transporter
KIM5_RS04660	COG0583	DNA-binding transcription factor activity
KIM5_RS04665	COG0277	FAD linked oxidase domain protein
KIM5_RS04670	COG0277	FAD linked oxidase domain protein
KIM5_RS04680	COG0247	lactate metabolic process
KIM5_RS04695	COG1376	ErfK ybiS ycfS ynhG family protein
KIM5_RS04700	COG1376	ErfK ybiS ycfS ynhG family protein
KIM5_RS04705	COG2818	Glycosylase
KIM5_RS04720	COG0667	Aldo Keto reductase
KIM5_RS04730	COG0124	histidyl-tRNA synthetase
KIM5_RS04735	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KIM5_RS04740	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KIM5_RS04745	COG2259	Doxx family
KIM5_RS04750	COG0625	glutathione transferase activity
KIM5_RS04760	COG0459	protein refolding
KIM5_RS04765	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KIM5_RS04775	COG0196	riboflavin kinase activity
KIM5_RS04800	COG0590	tRNA wobble adenosine to inosine editing
KIM5_RS04805	COG1187	pseudouridine synthase activity
KIM5_RS04810	COG0742	ribosomal rna small subunit methyltransferase
KIM5_RS04835	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KIM5_RS04835	COG0475	glutathione-regulated potassium exporter activity
KIM5_RS04840	COG0312	modulator of DNA gyrase
KIM5_RS04845	COG0483	inositol monophosphate 1-phosphatase activity
KIM5_RS04855	COG1519	Transferase
KIM5_RS04865	COG1663	tetraacyldisaccharide 4'-kinase activity
KIM5_RS04880	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KIM5_RS04890	COG3300	MHYT domain
KIM5_RS04890	COG5001	Diguanylate cyclase
KIM5_RS04900	COG3386	PFAM SMP-30 Gluconolaconase
KIM5_RS04905	COG0800	Aldolase
KIM5_RS04910	COG3734	2-keto-3-deoxy-galactonokinase
KIM5_RS04915	COG1028	Short-chain dehydrogenase reductase Sdr
KIM5_RS04920	COG1414	Transcriptional regulator
KIM5_RS04925	COG2197	response regulator
KIM5_RS04935	COG0489	protein tyrosine kinase activity
KIM5_RS04950	COG3158	transport of potassium into the cell
KIM5_RS04965	COG0356	it plays a direct role in the translocation of protons across the membrane
KIM5_RS04975	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KIM5_RS04980	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KIM5_RS04985	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KIM5_RS05005	COG0521	Mo-molybdopterin cofactor biosynthetic process
KIM5_RS05010	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KIM5_RS05020	COG0142	geranyltranstransferase activity
KIM5_RS05035	COG1914	H( )-stimulated, divalent metal cation uptake system
KIM5_RS05050	COG0752	glycyl-tRNA synthetase alpha subunit
KIM5_RS05065	COG1704	LemA family
KIM5_RS05070	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KIM5_RS05080	COG0151	Belongs to the GarS family
KIM5_RS05090	COG0840	transmembrane signaling receptor activity
KIM5_RS05095	COG1683	Conserved Protein
KIM5_RS05100	COG0751	glycine-tRNA ligase activity
KIM5_RS05105	COG2183	response to ionizing radiation
KIM5_RS05110	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KIM5_RS05115	COG0406	alpha-ribazole phosphatase activity
KIM5_RS05125	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KIM5_RS05145	COG0009	L-threonylcarbamoyladenylate synthase
KIM5_RS05160	COG4638	Rieske (2fe-2S)
KIM5_RS05180	COG1960	acyl-CoA dehydrogenase activity
KIM5_RS05195	COG1028	Short-chain dehydrogenase reductase Sdr
KIM5_RS05200	COG1733	regulation of RNA biosynthetic process
KIM5_RS05205	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KIM5_RS05215	COG0840	transmembrane signaling receptor activity
KIM5_RS05220	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KIM5_RS05230	COG1741	Belongs to the pirin family
KIM5_RS05240	COG1722	exodeoxyribonuclease VII activity
KIM5_RS05245	COG0123	including yeast histone deacetylase and acetoin utilization protein
KIM5_RS05255	COG1802	Transcriptional regulator
KIM5_RS05265	COG0318	PFAM AMP-dependent synthetase and ligase
KIM5_RS05280	COG0662	Cupin 2, conserved barrel domain protein
KIM5_RS05285	COG1268	BioY protein
KIM5_RS05290	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KIM5_RS05295	COG1122	ATPase activity
KIM5_RS05300	COG3214	Protein conserved in bacteria
KIM5_RS05305	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KIM5_RS05305	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KIM5_RS05310	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KIM5_RS05330	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KIM5_RS05335	COG0484	heat shock protein binding
KIM5_RS05345	COG0259	pyridoxamine-phosphate oxidase activity
KIM5_RS05355	COG1686	Belongs to the peptidase S11 family
KIM5_RS05370	COG0312	modulator of DNA gyrase
KIM5_RS05380	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KIM5_RS05380	COG1565	acr, cog1565
KIM5_RS05385	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KIM5_RS05390	COG0109	protoheme IX farnesyltransferase activity
KIM5_RS05400	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
KIM5_RS05430	COG3346	SURF1 family
KIM5_RS05435	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KIM5_RS05440	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KIM5_RS05445	COG0328	RNA-DNA hybrid ribonuclease activity
KIM5_RS05465	COG1678	Uncharacterized ACR, COG1678
KIM5_RS05475	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KIM5_RS05475	COG0678	peroxiredoxin activity
KIM5_RS05480	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KIM5_RS05485	COG2814	Major facilitator Superfamily
KIM5_RS05510	COG3485	protocatechuate 3,4-dioxygenase
KIM5_RS05530	COG1121	(ABC) transporter
KIM5_RS05535	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KIM5_RS05565	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KIM5_RS05570	COG0612	Peptidase, M16
KIM5_RS05590	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KIM5_RS05595	COG2814	Major facilitator Superfamily
KIM5_RS05635	COG2189	Belongs to the N(4) N(6)-methyltransferase family
KIM5_RS05650	COG1194	a g-specific adenine glycosylase
KIM5_RS05675	COG1196	nuclear chromosome segregation
KIM5_RS05680	COG0625	glutathione transferase activity
KIM5_RS05690	COG0574	Belongs to the PEP-utilizing enzyme family
KIM5_RS05690	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KIM5_RS05790	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KIM5_RS05900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KIM5_RS05905	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
KIM5_RS05930	COG1733	regulation of RNA biosynthetic process
KIM5_RS05945	COG3300	MHYT domain
KIM5_RS05945	COG5001	Diguanylate cyclase
KIM5_RS05960	COG3273	potassium ion transport
KIM5_RS05960	COG0471	metal ion transport
KIM5_RS06050	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
KIM5_RS06065	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
KIM5_RS06070	COG3842	ATPase activity
KIM5_RS06075	COG0395	ABC-type sugar transport system, permease component
KIM5_RS06090	COG1609	Transcriptional regulator
KIM5_RS06115	COG2207	Transcriptional regulator
KIM5_RS06120	COG1073	alpha beta
KIM5_RS06180	COG1840	ABC-type Fe3 transport system, periplasmic component
KIM5_RS06185	COG1840	ABC-type Fe3 transport system, periplasmic component
KIM5_RS06195	COG3842	ATPase activity
KIM5_RS06200	COG0483	inositol monophosphate 1-phosphatase activity
KIM5_RS06230	COG2169	Transcriptional regulator
KIM5_RS06230	COG1917	Cupin 2, conserved barrel domain protein
KIM5_RS06255	COG0640	Transcriptional regulator
KIM5_RS06260	COG1028	Short-chain dehydrogenase reductase Sdr
KIM5_RS06270	COG2329	Antibiotic biosynthesis monooxygenase
KIM5_RS06280	COG0625	glutathione transferase activity
KIM5_RS06290	COG0640	Transcriptional regulator
KIM5_RS06305	COG0596	Alpha beta hydrolase
KIM5_RS06325	COG1073	alpha beta
KIM5_RS06380	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KIM5_RS06390	COG1609	Transcriptional regulator
KIM5_RS06395	COG0583	DNA-binding transcription factor activity
KIM5_RS06425	COG2895	sulfate adenylyltransferase (ATP) activity
KIM5_RS06430	COG0175	sulfate reduction
KIM5_RS06435	COG0175	sulfate reduction
KIM5_RS06440	COG1959	2 iron, 2 sulfur cluster binding
KIM5_RS06450	COG0583	DNA-binding transcription factor activity
KIM5_RS06470	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
KIM5_RS06475	COG1012	belongs to the aldehyde dehydrogenase family
KIM5_RS06480	COG1309	transcriptional regulator
KIM5_RS06495	COG4943	cyclic-guanylate-specific phosphodiesterase activity
KIM5_RS06505	COG2226	methyltransferase
KIM5_RS06540	COG1349	DNA-binding transcription factor activity
KIM5_RS06560	COG1028	Short-chain dehydrogenase reductase Sdr
KIM5_RS06575	COG0583	DNA-binding transcription factor activity
KIM5_RS06585	COG1392	Phosphate transport regulator
KIM5_RS06590	COG0306	phosphate transporter
KIM5_RS06595	COG0435	Glutathione S-transferase
KIM5_RS06605	COG1881	PFAM PEBP family protein
KIM5_RS06635	COG0596	Alpha beta hydrolase
KIM5_RS06645	COG1793	dna ligase
KIM5_RS06655	COG1376	ErfK ybiS ycfS ynhG family protein
KIM5_RS06660	COG1376	ErfK ybiS ycfS ynhG family protein
KIM5_RS06665	COG1278	Cold shock
KIM5_RS06675	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KIM5_RS06685	COG1846	Transcriptional regulator
KIM5_RS06690	COG1764	response to oxidative stress
KIM5_RS06715	COG0488	(ABC) transporter
KIM5_RS06730	COG0488	(ABC) transporter
KIM5_RS06740	COG0433	COG0433 Predicted ATPase
KIM5_RS06755	COG3609	addiction module antidote protein, CC2985 family
KIM5_RS06760	COG1051	belongs to the nudix hydrolase family
KIM5_RS06770	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KIM5_RS06775	COG0583	DNA-binding transcription factor activity
KIM5_RS06790	COG3842	ATPase activity
KIM5_RS06795	COG1176	ABC-type spermidine putrescine transport system, permease component I
KIM5_RS06815	COG4106	trans-aconitate 2-methyltransferase activity
KIM5_RS06820	COG1253	flavin adenine dinucleotide binding
KIM5_RS06840	COG1064	alcohol dehydrogenase
KIM5_RS06845	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KIM5_RS06855	COG0583	DNA-binding transcription factor activity
KIM5_RS06880	COG0625	glutathione transferase activity
KIM5_RS06890	COG2814	Major facilitator Superfamily
KIM5_RS06900	COG0730	response to heat
KIM5_RS06905	COG2226	methyltransferase
KIM5_RS06915	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KIM5_RS06930	COG1280	lysine exporter protein (LysE YggA)
KIM5_RS06940	COG1082	Xylose isomerase domain protein TIM barrel
KIM5_RS06945	COG0673	inositol 2-dehydrogenase activity
KIM5_RS06955	COG1172	Belongs to the binding-protein-dependent transport system permease family
KIM5_RS06960	COG1129	ABC transporter
KIM5_RS06965	COG1609	Transcriptional regulator
KIM5_RS06975	COG2010	Cytochrome c
KIM5_RS07005	COG4993	Dehydrogenase
KIM5_RS07010	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KIM5_RS07015	COG0477	Major facilitator Superfamily
KIM5_RS07075	COG2514	catechol 2,3-dioxygenase activity
KIM5_RS07085	COG1272	protein, Hemolysin III
KIM5_RS07090	COG1247	-acetyltransferase
KIM5_RS07100	COG5425	PFAM Usg family protein
KIM5_RS07105	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KIM5_RS07110	COG0459	protein refolding
KIM5_RS07120	COG0438	transferase activity, transferring glycosyl groups
KIM5_RS07135	COG0071	Belongs to the small heat shock protein (HSP20) family
KIM5_RS07140	COG0071	Belongs to the small heat shock protein (HSP20) family
KIM5_RS07155	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KIM5_RS07170	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KIM5_RS07180	COG2111	Na H antiporter
KIM5_RS07180	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KIM5_RS07185	COG2111	Na H antiporter
KIM5_RS07190	COG1006	Multisubunit Na H antiporter MnhC subunit
KIM5_RS07200	COG0651	ATP synthesis coupled electron transport
KIM5_RS07205	COG1863	multisubunit Na H antiporter MnhE subunit
KIM5_RS07210	COG2212	antiporter activity
KIM5_RS07215	COG1320	monovalent cation:proton antiporter activity
KIM5_RS07220	COG4957	zinc ion binding
KIM5_RS07225	COG2166	iron-sulfur cluster assembly
KIM5_RS07235	COG2205	protein histidine kinase activity
KIM5_RS07245	COG0840	transmembrane signaling receptor activity
KIM5_RS07270	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KIM5_RS07275	COG2983	Belongs to the UPF0260 family
KIM5_RS07300	COG4221	oxidoreductase activity
KIM5_RS07305	COG3239	Fatty acid desaturase
KIM5_RS07320	COG0583	DNA-binding transcription factor activity
KIM5_RS07335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KIM5_RS07350	COG0625	glutathione transferase activity
KIM5_RS07365	COG1309	transcriptional regulator
KIM5_RS07405	COG4235	cytochrome complex assembly
KIM5_RS07410	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
KIM5_RS07415	COG1138	Cytochrome C-type biogenesis protein
KIM5_RS07420	COG3088	subunit of a heme lyase
KIM5_RS07425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KIM5_RS07430	COG0745	RESPONSE REGULATOR receiver
KIM5_RS07435	COG2205	protein histidine kinase activity
KIM5_RS07440	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KIM5_RS07445	COG2202	Pas domain
KIM5_RS07445	COG2205	protein histidine kinase activity
KIM5_RS07450	COG0308	aminopeptidase N
KIM5_RS07480	COG0443	Heat shock 70 kDa protein
KIM5_RS07515	COG1376	ErfK ybiS ycfS ynhG family protein
KIM5_RS07530	COG2239	Acts as a magnesium transporter
KIM5_RS07535	COG2814	Major facilitator Superfamily
KIM5_RS07545	COG0174	glutamine synthetase
KIM5_RS07555	COG3609	addiction module antidote protein, CC2985 family
KIM5_RS07560	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KIM5_RS07565	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KIM5_RS07570	COG0463	Glycosyl transferase, family 2
KIM5_RS07575	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KIM5_RS07585	COG4941	Belongs to the sigma-70 factor family
KIM5_RS07595	COG3795	YCII-related domain
KIM5_RS07600	COG3795	YCII-related domain
KIM5_RS07610	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KIM5_RS07630	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KIM5_RS07665	COG3718	enzyme involved in inositol metabolism
KIM5_RS07670	COG1082	Xylose isomerase domain protein TIM barrel
KIM5_RS07675	COG3962	Belongs to the TPP enzyme family
KIM5_RS07680	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KIM5_RS07690	COG0673	inositol 2-dehydrogenase activity
KIM5_RS07720	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KIM5_RS07725	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KIM5_RS07735	COG1758	RNA polymerase activity
KIM5_RS07755	COG0736	holo-[acyl-carrier-protein] synthase activity
KIM5_RS07760	COG0681	Belongs to the peptidase S26 family
KIM5_RS07765	COG0571	ribonuclease III activity
KIM5_RS07770	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KIM5_RS07775	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KIM5_RS07785	COG1381	Involved in DNA repair and RecF pathway recombination
KIM5_RS07800	COG1418	mRNA catabolic process
KIM5_RS07815	COG2032	superoxide dismutase activity
KIM5_RS07820	COG0668	transmembrane transport
KIM5_RS07830	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
KIM5_RS07855	COG1051	belongs to the nudix hydrolase family
KIM5_RS07860	COG1742	UPF0060 membrane protein
KIM5_RS07870	COG1183	phosphatidylcholine synthase activity
KIM5_RS07875	COG0688	phosphatidylethanolamine metabolic process
KIM5_RS07880	COG5265	(ABC) transporter
KIM5_RS07900	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KIM5_RS07930	COG0215	cysteine-tRNA ligase activity
KIM5_RS07940	COG4221	oxidoreductase activity
KIM5_RS07945	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KIM5_RS07950	COG1286	toxin biosynthetic process
KIM5_RS07960	COG1280	lysine exporter protein (LysE YggA)
KIM5_RS07965	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KIM5_RS07970	COG0305	Participates in initiation and elongation during chromosome replication
KIM5_RS07975	COG0359	binds to the 23S rRNA
KIM5_RS07985	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KIM5_RS07990	COG0360	Binds together with S18 to 16S ribosomal RNA
KIM5_RS07995	COG0667	Aldo Keto reductase
KIM5_RS08000	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KIM5_RS08010	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KIM5_RS08015	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KIM5_RS08020	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KIM5_RS08025	COG1561	YicC-like family, N-terminal region
KIM5_RS08030	COG0194	GDP metabolic process
KIM5_RS08035	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KIM5_RS08040	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KIM5_RS08050	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
KIM5_RS08065	COG0671	phosphoesterase, PA-phosphatase related
KIM5_RS08070	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KIM5_RS08085	COG1505	serine-type exopeptidase activity
KIM5_RS08095	COG0488	(ABC) transporter
KIM5_RS08100	COG3706	GGDEF domain
KIM5_RS08120	COG0105	UTP biosynthetic process
KIM5_RS08140	COG0314	molybdopterin synthase activity
KIM5_RS08150	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KIM5_RS08155	COG0322	excinuclease ABC activity
KIM5_RS08160	COG1028	Short-chain dehydrogenase reductase Sdr
KIM5_RS08175	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KIM5_RS08180	COG0243	molybdopterin cofactor binding
KIM5_RS08185	COG0494	nUDIX hydrolase
KIM5_RS08190	COG3454	Phosphonate metabolism
KIM5_RS08195	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KIM5_RS08200	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
KIM5_RS08205	COG0628	permease
KIM5_RS08215	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KIM5_RS08220	COG0248	Ppx GppA phosphatase
KIM5_RS08230	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
KIM5_RS08235	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
KIM5_RS08250	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KIM5_RS08260	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KIM5_RS08270	COG3654	unkown
KIM5_RS08275	COG2336	PFAM SpoVT AbrB
KIM5_RS08290	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
KIM5_RS08300	COG0113	porphobilinogen synthase activity
KIM5_RS08320	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KIM5_RS08325	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KIM5_RS08330	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KIM5_RS08330	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KIM5_RS08340	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KIM5_RS08345	COG1091	dTDP-4-dehydrorhamnose reductase activity
KIM5_RS08350	COG1088	dTDP-glucose 4,6-dehydratase activity
KIM5_RS08355	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
KIM5_RS08395	COG1215	transferase activity, transferring glycosyl groups
KIM5_RS08415	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KIM5_RS08420	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KIM5_RS08425	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
KIM5_RS08445	COG0416	fatty acid biosynthetic process
KIM5_RS08450	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KIM5_RS08455	COG0776	regulation of translation
KIM5_RS08505	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KIM5_RS08515	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KIM5_RS08540	COG1653	transport
KIM5_RS08545	COG1175	transmembrane transport
KIM5_RS08550	COG0395	ABC-type sugar transport system, permease component
KIM5_RS08565	COG0297	glycogen (starch) synthase activity
KIM5_RS08590	COG1612	heme a metabolic process
KIM5_RS08600	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KIM5_RS08605	COG0010	Belongs to the arginase family
KIM5_RS08615	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KIM5_RS08620	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KIM5_RS08635	COG1024	Enoyl-CoA hydratase
KIM5_RS08650	COG1832	CoA-binding protein
KIM5_RS08670	COG5001	Diguanylate cyclase
KIM5_RS08675	COG2124	cytochrome p450
KIM5_RS08680	COG3706	GGDEF domain
KIM5_RS08685	COG0740	serine-type endopeptidase activity
KIM5_RS08690	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KIM5_RS08695	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KIM5_RS08700	COG0776	regulation of translation
KIM5_RS08715	COG0667	Aldo Keto reductase
KIM5_RS08735	COG0386	Belongs to the glutathione peroxidase family
KIM5_RS08760	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KIM5_RS08765	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KIM5_RS08770	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KIM5_RS08775	COG0649	NAD binding
KIM5_RS08785	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
KIM5_RS08790	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KIM5_RS08795	COG3743	rRNA binding
KIM5_RS08795	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KIM5_RS08805	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
KIM5_RS08810	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KIM5_RS08820	COG0713	ATP synthesis coupled electron transport
KIM5_RS08835	COG1007	ATP synthesis coupled electron transport
KIM5_RS08840	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
KIM5_RS08840	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
KIM5_RS08850	COG0346	lactoylglutathione lyase activity
KIM5_RS08865	COG0442	prolyl-tRNA aminoacylation
KIM5_RS08875	COG1136	(ABC) transporter
KIM5_RS08895	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KIM5_RS08915	COG0784	Response regulator, receiver
KIM5_RS08925	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KIM5_RS08930	COG0477	Major facilitator Superfamily
KIM5_RS08940	COG0557	exoribonuclease II activity
KIM5_RS08945	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KIM5_RS08950	COG0758	DNA mediated transformation
KIM5_RS08955	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KIM5_RS08965	COG0540	Belongs to the ATCase OTCase family
KIM5_RS08970	COG1960	acyl-CoA dehydrogenase activity
KIM5_RS08980	COG1530	ribonuclease E activity
KIM5_RS08985	COG0860	N-Acetylmuramoyl-L-alanine amidase
KIM5_RS08995	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KIM5_RS09015	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KIM5_RS09040	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KIM5_RS09055	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KIM5_RS09060	COG1086	Polysaccharide biosynthesis protein
KIM5_RS09070	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KIM5_RS09080	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KIM5_RS09085	COG0081	regulation of translation
KIM5_RS09090	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KIM5_RS09095	COG0222	ribosome binding
KIM5_RS09100	COG0085	RNA polymerase activity
KIM5_RS09105	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KIM5_RS09115	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KIM5_RS09120	COG0049	tRNA binding
KIM5_RS09125	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KIM5_RS09130	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KIM5_RS09135	COG0051	transcription antitermination factor activity, RNA binding
KIM5_RS09140	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KIM5_RS09145	COG0088	Forms part of the polypeptide exit tunnel
KIM5_RS09150	COG0089	rRNA binding
KIM5_RS09155	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KIM5_RS09160	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KIM5_RS09165	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KIM5_RS09170	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KIM5_RS09175	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KIM5_RS09180	COG0255	Belongs to the universal ribosomal protein uL29 family
KIM5_RS09185	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KIM5_RS09190	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KIM5_RS09195	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KIM5_RS09200	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KIM5_RS09205	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KIM5_RS09210	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KIM5_RS09215	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KIM5_RS09220	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KIM5_RS09225	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KIM5_RS09230	COG1841	ribosomal large subunit assembly
KIM5_RS09235	COG0200	Binds to the 23S rRNA
KIM5_RS09245	COG0563	adenylate kinase activity
KIM5_RS09250	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KIM5_RS09255	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KIM5_RS09260	COG0202	RNA polymerase activity
KIM5_RS09265	COG0203	ribosomal protein L17
KIM5_RS09275	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
KIM5_RS09280	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KIM5_RS09285	COG0129	dihydroxy-acid dehydratase activity
KIM5_RS09305	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KIM5_RS09315	COG0508	dehydrogenase complex catalyzes the overall conversion of
KIM5_RS09315	COG0596	Alpha beta hydrolase
KIM5_RS09320	COG1028	Short-chain dehydrogenase reductase Sdr
KIM5_RS09325	COG0583	DNA-binding transcription factor activity
KIM5_RS09345	COG5002	protein histidine kinase activity
KIM5_RS09355	COG1609	Transcriptional regulator
KIM5_RS09365	COG1024	Enoyl-CoA hydratase
KIM5_RS09370	COG1012	belongs to the aldehyde dehydrogenase family
KIM5_RS09375	COG1653	transport
KIM5_RS09380	COG1175	transmembrane transport
KIM5_RS09385	COG0395	ABC-type sugar transport system, permease component
KIM5_RS09390	COG3842	ATPase activity
KIM5_RS09405	COG0673	inositol 2-dehydrogenase activity
KIM5_RS09410	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KIM5_RS09440	COG2197	response regulator
KIM5_RS09445	COG4585	Histidine kinase
KIM5_RS09450	COG2226	methyltransferase
KIM5_RS09495	COG1522	sequence-specific DNA binding
KIM5_RS09500	COG1522	sequence-specific DNA binding
KIM5_RS09510	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
KIM5_RS09520	COG0625	glutathione transferase activity
KIM5_RS09555	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KIM5_RS09560	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
KIM5_RS09570	COG1058	Belongs to the CinA family
KIM5_RS09570	COG1546	Belongs to the CinA family
KIM5_RS09585	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KIM5_RS09600	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KIM5_RS09605	COG0583	DNA-binding transcription factor activity
KIM5_RS09610	COG0737	Belongs to the 5'-nucleotidase family
KIM5_RS09625	COG1522	sequence-specific DNA binding
KIM5_RS09630	COG0686	Belongs to the AlaDH PNT family
KIM5_RS09650	COG2897	thiosulfate sulfurtransferase activity
KIM5_RS09665	COG3806	Anti-sigma factor
KIM5_RS09670	COG0300	oxidoreductase activity
KIM5_RS09675	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KIM5_RS09695	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KIM5_RS09700	COG0243	molybdopterin cofactor binding
KIM5_RS09710	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KIM5_RS09720	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KIM5_RS09730	COG0450	alkyl hydroperoxide reductase
KIM5_RS09790	COG3237	CsbD-like
KIM5_RS09825	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KIM5_RS09835	COG0525	valine-tRNA ligase activity
KIM5_RS09860	COG0316	Belongs to the HesB IscA family
KIM5_RS09865	COG0232	Belongs to the dGTPase family. Type 2 subfamily
KIM5_RS09870	COG0018	arginyl-trna synthetase
KIM5_RS09880	COG1472	Belongs to the glycosyl hydrolase 3 family
KIM5_RS09885	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KIM5_RS09890	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KIM5_RS09895	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KIM5_RS09900	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KIM5_RS09905	COG0805	protein transport
KIM5_RS09910	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KIM5_RS09915	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KIM5_RS09920	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KIM5_RS09935	COG1862	Preprotein translocase
KIM5_RS09960	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KIM5_RS09990	COG0544	peptidyl-prolyl cis-trans isomerase activity
KIM5_RS10000	COG1032	radical SAM domain protein
KIM5_RS10025	COG2003	Belongs to the UPF0758 family
KIM5_RS10030	COG0024	Methionine aminopeptidase
KIM5_RS10045	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KIM5_RS10050	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KIM5_RS10055	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KIM5_RS10060	COG0154	amidase activity
KIM5_RS10075	COG3811	Belongs to the UPF0386 family
KIM5_RS10090	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KIM5_RS10110	COG4765	Protein conserved in bacteria
KIM5_RS10115	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KIM5_RS10125	COG0511	ligase activity, forming carbon-carbon bonds
KIM5_RS10130	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KIM5_RS10140	COG0436	Aminotransferase
KIM5_RS10150	COG3243	poly(R)-hydroxyalkanoic acid synthase
KIM5_RS10160	COG0436	Aminotransferase
KIM5_RS10175	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KIM5_RS10185	COG3328	transposase activity
KIM5_RS10210	COG1278	Cold shock
KIM5_RS10280	COG1126	abc transporter atp-binding protein
KIM5_RS10285	COG0765	amino acid transport
KIM5_RS10290	COG4597	amino acid ABC transporter
KIM5_RS10295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KIM5_RS10300	COG0626	cystathionine gamma-synthase activity
KIM5_RS10315	COG2267	carboxylic ester hydrolase activity
KIM5_RS10335	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KIM5_RS10355	COG3971	2-oxopent-4-enoate hydratase activity
KIM5_RS10360	COG3485	protocatechuate 3,4-dioxygenase
KIM5_RS10380	COG0765	amino acid transport
KIM5_RS10385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KIM5_RS10390	COG1126	abc transporter atp-binding protein
KIM5_RS10395	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KIM5_RS10405	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KIM5_RS10410	COG0537	adenosine 5'-monophosphoramidase activity
KIM5_RS10455	COG0052	Belongs to the universal ribosomal protein uS2 family
KIM5_RS10460	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KIM5_RS10465	COG0528	UMP kinase activity
KIM5_RS10470	COG0233	cytoplasmic translational termination
KIM5_RS10475	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KIM5_RS10485	COG0750	zinc metalloprotease
KIM5_RS10495	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KIM5_RS10500	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KIM5_RS10505	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KIM5_RS10510	COG3494	Protein of unknown function (DUF1009)
KIM5_RS10515	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KIM5_RS10525	COG2333	competence protein COMEC
KIM5_RS10525	COG0658	competence protein
KIM5_RS10530	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KIM5_RS10540	COG2877	3-deoxy-8-phosphooctulonate synthase activity
KIM5_RS10545	COG0148	phosphopyruvate hydratase activity
KIM5_RS10555	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KIM5_RS10560	COG0508	dehydrogenase complex catalyzes the overall conversion of
KIM5_RS10560	COG0022	dehydrogenase e1 component
KIM5_RS10565	COG0508	dehydrogenase complex catalyzes the overall conversion of
KIM5_RS10580	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KIM5_RS10595	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KIM5_RS10615	COG2867	negative regulation of translational initiation
KIM5_RS10620	COG1058	Belongs to the CinA family
KIM5_RS10620	COG1546	Belongs to the CinA family
KIM5_RS10625	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KIM5_RS10625	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KIM5_RS10640	COG2204	response regulator
KIM5_RS10665	COG1231	oxidoreductase activity
KIM5_RS10670	COG0583	DNA-binding transcription factor activity
KIM5_RS10675	COG2814	Major facilitator Superfamily
KIM5_RS10680	COG0667	Aldo Keto reductase
KIM5_RS10685	COG5000	phosphorelay sensor kinase activity
KIM5_RS10690	COG2204	response regulator
KIM5_RS10695	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KIM5_RS10700	COG1923	regulation of RNA biosynthetic process
KIM5_RS10705	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KIM5_RS10710	COG3956	TIGRFAM MazG family protein
KIM5_RS10720	COG1648	precorrin-2 dehydrogenase activity
KIM5_RS10720	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KIM5_RS10740	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KIM5_RS10745	COG0679	Auxin Efflux Carrier
KIM5_RS10750	COG0785	Cytochrome C biogenesis protein
KIM5_RS10785	COG1484	DNA-dependent DNA replication
KIM5_RS10790	COG4584	PFAM Integrase catalytic
KIM5_RS10830	COG0582	viral genome integration into host DNA
KIM5_RS10875	COG5265	(ABC) transporter
KIM5_RS10885	COG1879	ABC-type sugar transport system periplasmic component
KIM5_RS10895	COG1172	Belongs to the binding-protein-dependent transport system permease family
KIM5_RS10900	COG1737	Transcriptional regulator
KIM5_RS10945	COG0300	oxidoreductase activity
KIM5_RS10950	COG2207	Transcriptional regulator
KIM5_RS10975	COG1653	transport
KIM5_RS10980	COG1175	transmembrane transport
KIM5_RS10985	COG0395	ABC-type sugar transport system, permease component
KIM5_RS10990	COG3842	ATPase activity
KIM5_RS10995	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KIM5_RS11000	COG1312	Catalyzes the dehydration of D-mannonate
KIM5_RS11005	COG2186	Transcriptional regulator
KIM5_RS11010	COG0747	negative chemotaxis
KIM5_RS11015	COG0601	transmembrane transport
KIM5_RS11020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KIM5_RS11025	COG0444	Belongs to the ABC transporter superfamily
KIM5_RS11035	COG1609	Transcriptional regulator
KIM5_RS11055	COG1175	transmembrane transport
KIM5_RS11060	COG0395	ABC-type sugar transport system, permease component
KIM5_RS11090	COG1136	(ABC) transporter
KIM5_RS11090	COG0577	efflux transmembrane transporter activity
KIM5_RS11095	COG0577	efflux transmembrane transporter activity
KIM5_RS11095	COG1136	(ABC) transporter
KIM5_RS11110	COG1183	phosphatidylcholine synthase activity
KIM5_RS11120	COG3845	ABC transporter
KIM5_RS11130	COG1079	Belongs to the binding-protein-dependent transport system permease family
KIM5_RS11140	COG1879	ABC-type sugar transport system periplasmic component
KIM5_RS11145	COG1129	ABC transporter
KIM5_RS11150	COG1172	Belongs to the binding-protein-dependent transport system permease family
KIM5_RS11155	COG1172	Belongs to the binding-protein-dependent transport system permease family
KIM5_RS11160	COG2186	Transcriptional regulator
KIM5_RS11165	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KIM5_RS11170	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KIM5_RS11180	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KIM5_RS11190	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KIM5_RS11205	COG4166	transmembrane transport
KIM5_RS11220	COG0174	glutamine synthetase
KIM5_RS11225	COG0347	Belongs to the P(II) protein family
KIM5_RS11230	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KIM5_RS11230	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KIM5_RS11245	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KIM5_RS11250	COG0629	single-stranded DNA binding
KIM5_RS11255	COG2095	MarC family integral membrane protein
KIM5_RS11260	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KIM5_RS11270	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KIM5_RS11285	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KIM5_RS11290	COG0343	queuine tRNA-ribosyltransferase activity
KIM5_RS11305	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KIM5_RS11335	COG1175	transmembrane transport
KIM5_RS11350	COG1609	Transcriptional regulator
KIM5_RS11355	COG0612	Peptidase, M16
KIM5_RS11405	COG1802	Transcriptional regulator
KIM5_RS11420	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KIM5_RS11440	COG1522	sequence-specific DNA binding
KIM5_RS11455	COG1473	amidohydrolase
KIM5_RS11470	COG0861	Integral membrane protein TerC family
KIM5_RS11475	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KIM5_RS11475	COG0321	lipoyl(octanoyl) transferase activity
KIM5_RS11480	COG0084	hydrolase, TatD family'
KIM5_RS11485	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KIM5_RS11490	COG0730	response to heat
KIM5_RS11500	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KIM5_RS11550	COG2824	Alkylphosphonate utilization operon protein PhnA
KIM5_RS11585	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KIM5_RS11590	COG0134	indole-3-glycerol-phosphate synthase activity
KIM5_RS11595	COG0315	cyclic pyranopterin monophosphate synthase activity
KIM5_RS11600	COG0303	'Molybdopterin
KIM5_RS11610	COG0513	Belongs to the DEAD box helicase family
KIM5_RS11625	COG0372	Belongs to the citrate synthase family
KIM5_RS11630	COG0372	Belongs to the citrate synthase family
KIM5_RS11640	COG0504	CTP synthase activity
KIM5_RS11650	COG0149	triose-phosphate isomerase activity
KIM5_RS11660	COG0187	DNA topoisomerase II activity
KIM5_RS11670	COG0628	permease
KIM5_RS11705	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KIM5_RS11715	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
KIM5_RS11720	COG0822	iron-sulfur transferase activity
KIM5_RS11725	COG0302	gtp cyclohydrolase
KIM5_RS11730	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KIM5_RS11735	COG1752	Esterase of the alpha-beta hydrolase superfamily
KIM5_RS11775	COG1686	Belongs to the peptidase S11 family
KIM5_RS11790	COG1760	l-serine dehydratase
KIM5_RS11805	COG1250	3-hydroxyacyl-CoA dehydrogenase
KIM5_RS11810	COG1960	acyl-CoA dehydrogenase activity
KIM5_RS11815	COG0583	DNA-binding transcription factor activity
KIM5_RS11820	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KIM5_RS11825	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KIM5_RS11835	COG0431	NADPH-dependent FMN reductase
KIM5_RS11840	COG1063	alcohol dehydrogenase
KIM5_RS11845	COG0683	leucine binding
KIM5_RS11855	COG0148	phosphopyruvate hydratase activity
KIM5_RS11910	COG2239	Acts as a magnesium transporter
KIM5_RS11915	COG0242	peptide deformylase activity
KIM5_RS11935	COG0321	lipoyl(octanoyl) transferase activity
KIM5_RS11950	COG4770	biotin carboxylase activity
KIM5_RS11955	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KIM5_RS11960	COG2153	protein acetylation
KIM5_RS11965	COG1671	Belongs to the UPF0178 family
KIM5_RS11975	COG2259	Doxx family
KIM5_RS11980	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KIM5_RS11995	COG0546	phosphoglycolate phosphatase activity
KIM5_RS12005	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KIM5_RS12030	COG0509	glycine decarboxylation via glycine cleavage system
KIM5_RS12035	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KIM5_RS12035	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KIM5_RS12050	COG0316	Belongs to the HesB IscA family
KIM5_RS12055	COG2151	metal-sulfur cluster biosynthetic enzyme
KIM5_RS12060	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KIM5_RS12065	COG0719	Fe-S assembly protein
KIM5_RS12070	COG0396	ATPase activity
KIM5_RS12080	COG0719	Fe-S assembly protein
KIM5_RS12085	COG1104	cysteine desulfurase activity
KIM5_RS12090	COG2945	thiolester hydrolase activity
KIM5_RS12100	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KIM5_RS12105	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KIM5_RS12125	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KIM5_RS12130	COG2833	Protein of unknown function (DUF455)
KIM5_RS12135	COG0739	heme binding
KIM5_RS12135	COG0741	lytic transglycosylase activity
KIM5_RS12135	COG1196	nuclear chromosome segregation
KIM5_RS12140	COG0513	Belongs to the DEAD box helicase family
KIM5_RS12155	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KIM5_RS12180	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KIM5_RS12210	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KIM5_RS12215	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KIM5_RS12220	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
KIM5_RS12225	COG0047	phosphoribosylformylglycinamidine synthase activity
KIM5_RS12240	COG2186	Transcriptional regulator
KIM5_RS12250	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KIM5_RS12275	COG2814	Major facilitator Superfamily
KIM5_RS12280	COG2814	Major facilitator Superfamily
KIM5_RS12290	COG0483	inositol monophosphate 1-phosphatase activity
KIM5_RS12295	COG0483	inositol monophosphate 1-phosphatase activity
KIM5_RS12300	COG0037	tRNA processing
KIM5_RS12305	COG2066	Belongs to the glutaminase family
KIM5_RS12310	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KIM5_RS12330	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KIM5_RS12335	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
KIM5_RS12350	COG0538	isocitrate dehydrogenase activity
KIM5_RS12370	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KIM5_RS12375	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KIM5_RS12385	COG2313	pseudouridylate synthase activity
KIM5_RS12415	COG3106	COG3106 Predicted ATPase
KIM5_RS12420	COG3768	UPF0283 membrane protein
KIM5_RS12430	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KIM5_RS12440	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KIM5_RS12450	COG0633	Ferredoxin
KIM5_RS12470	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KIM5_RS12475	COG1686	Belongs to the peptidase S11 family
KIM5_RS12495	COG1127	ABC transporter
KIM5_RS12505	COG4948	Mandelate Racemase Muconate Lactonizing
KIM5_RS12510	COG2814	Major facilitator Superfamily
KIM5_RS12520	COG0588	phosphoglycerate mutase activity
KIM5_RS12530	COG0281	malic enzyme
KIM5_RS12530	COG0280	phosphate acetyltransferase
KIM5_RS12535	COG0328	RNA-DNA hybrid ribonuclease activity
KIM5_RS12540	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
KIM5_RS12550	COG0778	Nitroreductase
KIM5_RS12555	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KIM5_RS12560	COG0823	Involved in the tonB-independent uptake of proteins
KIM5_RS12575	COG0590	tRNA wobble adenosine to inosine editing
KIM5_RS12585	COG1132	(ABC) transporter
KIM5_RS12590	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
KIM5_RS12615	COG1254	Belongs to the acylphosphatase family
KIM5_RS12625	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KIM5_RS12630	COG0546	phosphoglycolate phosphatase activity
KIM5_RS12635	COG2989	Protein conserved in bacteria
KIM5_RS12645	COG0114	fumarate hydratase activity
KIM5_RS12650	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KIM5_RS12660	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
KIM5_RS12660	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
KIM5_RS12665	COG3706	GGDEF domain
KIM5_RS12680	COG1846	Transcriptional regulator
KIM5_RS12695	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KIM5_RS12700	COG2226	methyltransferase
KIM5_RS12710	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KIM5_RS12715	COG1120	ATPase activity
KIM5_RS12720	COG2390	Transcriptional regulator
KIM5_RS12725	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KIM5_RS12730	COG3958	Transketolase
KIM5_RS12735	COG3959	Transketolase, thiamine diphosphate binding domain
KIM5_RS12740	COG1172	Belongs to the binding-protein-dependent transport system permease family
KIM5_RS12745	COG1879	ABC-type sugar transport system periplasmic component
KIM5_RS12755	COG1028	Short-chain dehydrogenase reductase Sdr
KIM5_RS12760	COG1028	Short-chain dehydrogenase reductase Sdr
KIM5_RS12775	COG0746	molybdenum cofactor guanylyltransferase activity
KIM5_RS12780	COG1763	Mo-molybdopterin cofactor biosynthetic process
KIM5_RS12785	COG4191	Histidine kinase
KIM5_RS12785	COG0784	Response regulator, receiver
KIM5_RS12790	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
KIM5_RS12800	COG1764	response to oxidative stress
KIM5_RS12805	COG2205	protein histidine kinase activity
KIM5_RS12815	COG0596	Alpha beta hydrolase
KIM5_RS12835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KIM5_RS12840	COG4215	(ABC) transporter
KIM5_RS12850	COG5425	PFAM Usg family protein
KIM5_RS12870	COG0640	Transcriptional regulator
KIM5_RS12910	COG2084	Dehydrogenase
KIM5_RS12920	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KIM5_RS12925	COG0583	DNA-binding transcription factor activity
KIM5_RS12940	COG1522	sequence-specific DNA binding
KIM5_RS12945	COG1573	uracil-dna glycosylase
KIM5_RS12955	COG2202	Pas domain
KIM5_RS12955	COG2205	protein histidine kinase activity
KIM5_RS12965	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
KIM5_RS12970	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
KIM5_RS12985	COG0583	DNA-binding transcription factor activity
KIM5_RS12990	COG1028	Short-chain dehydrogenase reductase Sdr
KIM5_RS12995	COG0842	Transport permease protein
KIM5_RS13000	COG1131	(ABC) transporter
KIM5_RS13005	COG3507	Belongs to the glycosyl hydrolase 43 family
KIM5_RS13010	COG0667	Aldo Keto reductase
KIM5_RS13035	COG0395	ABC-type sugar transport system, permease component
KIM5_RS13040	COG1175	transmembrane transport
KIM5_RS13075	COG1247	-acetyltransferase
KIM5_RS13080	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KIM5_RS13110	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KIM5_RS13120	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KIM5_RS13125	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KIM5_RS13215	COG1492	cobalamin metabolic process
KIM5_RS13235	COG0583	DNA-binding transcription factor activity
KIM5_RS13250	COG0583	DNA-binding transcription factor activity
KIM5_RS13255	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KIM5_RS13260	COG1285	pathogenesis
KIM5_RS13290	COG1566	PFAM secretion protein HlyD family protein
KIM5_RS13310	COG0668	transmembrane transport
KIM5_RS13325	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KIM5_RS13350	COG0745	RESPONSE REGULATOR receiver
KIM5_RS13365	COG0640	Transcriptional regulator
KIM5_RS13375	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KIM5_RS13380	COG1393	Belongs to the ArsC family
KIM5_RS13385	COG0431	NADPH-dependent FMN reductase
KIM5_RS13400	COG3264	Mechanosensitive ion channel
KIM5_RS13400	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
KIM5_RS13410	COG0745	RESPONSE REGULATOR receiver
KIM5_RS13425	COG1175	transmembrane transport
KIM5_RS13430	COG0395	ABC-type sugar transport system, permease component
KIM5_RS13445	COG3842	ATPase activity
KIM5_RS13455	COG1461	Dihydroxyacetone kinase
KIM5_RS13470	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KIM5_RS13480	COG2376	Dihydroxyacetone kinase
KIM5_RS13495	COG1846	Transcriptional regulator
KIM5_RS13500	COG0494	nUDIX hydrolase
KIM5_RS13510	COG1764	response to oxidative stress
KIM5_RS13530	COG1607	acyl-coa hydrolase
KIM5_RS13550	COG0477	Major facilitator Superfamily
KIM5_RS13560	COG0702	epimerase
KIM5_RS13565	COG0583	DNA-binding transcription factor activity
KIM5_RS13575	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KIM5_RS13620	COG0556	nucleotide-excision repair
KIM5_RS13625	COG0456	acetyltransferase
KIM5_RS13635	COG2135	peptidase activity
KIM5_RS13655	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KIM5_RS13660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KIM5_RS13700	COG3850	Histidine kinase
KIM5_RS13700	COG0642	Histidine kinase
KIM5_RS13745	COG2354	Protein conserved in bacteria
KIM5_RS13765	COG0137	argininosuccinate synthase activity
KIM5_RS13775	COG1132	(ABC) transporter
KIM5_RS13795	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KIM5_RS13805	COG0456	acetyltransferase
KIM5_RS13805	COG0454	-acetyltransferase
KIM5_RS13825	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KIM5_RS13830	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KIM5_RS13840	COG3158	transport of potassium into the cell
KIM5_RS13875	COG1136	(ABC) transporter
KIM5_RS13880	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KIM5_RS13885	COG1917	Cupin 2, conserved barrel domain protein
KIM5_RS13885	COG2207	Transcriptional regulator
KIM5_RS13900	COG1845	cytochrome c oxidase, subunit III
KIM5_RS13905	COG1845	cytochrome c oxidase, subunit III
KIM5_RS13910	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KIM5_RS13915	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KIM5_RS13940	COG3453	Protein conserved in bacteria
KIM5_RS13940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KIM5_RS13950	COG2207	Transcriptional regulator
KIM5_RS13960	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KIM5_RS14035	COG5001	Diguanylate cyclase
KIM5_RS14035	COG3300	MHYT domain
KIM5_RS14050	COG2208	phosphoserine phosphatase activity
KIM5_RS14080	COG1335	isochorismatase
KIM5_RS14090	COG5001	Diguanylate cyclase
KIM5_RS14090	COG3300	MHYT domain
KIM5_RS14100	COG3920	Histidine kinase
KIM5_RS14100	COG2202	Pas domain
KIM5_RS14120	COG0395	ABC-type sugar transport system, permease component
KIM5_RS14135	COG1846	Transcriptional regulator
KIM5_RS14135	COG1940	carbohydrate kinase activity
KIM5_RS14150	COG0697	spore germination
KIM5_RS14155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KIM5_RS14160	COG2204	response regulator
KIM5_RS14165	COG5002	protein histidine kinase activity
KIM5_RS14170	COG1214	PFAM Peptidase M22, glycoprotease
KIM5_RS14170	COG0456	acetyltransferase
KIM5_RS14195	COG1028	Short-chain dehydrogenase reductase Sdr
KIM5_RS14205	COG0584	glycerophosphoryl diester phosphodiesterase
KIM5_RS14210	COG3842	ATPase activity
KIM5_RS14220	COG1175	transmembrane transport
KIM5_RS14235	COG0305	Participates in initiation and elongation during chromosome replication
KIM5_RS14240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KIM5_RS14245	COG0583	DNA-binding transcription factor activity
KIM5_RS14265	COG1120	ATPase activity
KIM5_RS14270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KIM5_RS14275	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KIM5_RS14285	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
KIM5_RS14325	COG0583	DNA-binding transcription factor activity
KIM5_RS14415	COG2963	transposase activity
KIM5_RS14425	COG4372	Transposase
KIM5_RS14445	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KIM5_RS14450	COG1121	(ABC) transporter
KIM5_RS14480	COG1253	flavin adenine dinucleotide binding
KIM5_RS14675	COG3547	Transposase (IS116 IS110 IS902 family)
KIM5_RS14685	COG2433	Pfam Transposase IS66
KIM5_RS14690	COG2963	transposase activity
KIM5_RS14770	COG0384	phenazine biosynthesis protein PhzF
KIM5_RS14810	COG1846	Transcriptional regulator
KIM5_RS14815	COG0667	Aldo Keto reductase
KIM5_RS14820	COG5634	Uncharacterized conserved protein (DUF2278)
KIM5_RS14830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KIM5_RS14835	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KIM5_RS14855	COG1260	myo-inositol-1-phosphate synthase
KIM5_RS14895	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KIM5_RS14910	COG1741	Belongs to the pirin family
KIM5_RS14920	COG1335	isochorismatase
KIM5_RS14925	COG0583	DNA-binding transcription factor activity
KIM5_RS14930	COG1028	Short-chain dehydrogenase reductase Sdr
KIM5_RS14935	COG1069	ribulokinase activity
KIM5_RS14945	COG0463	Glycosyl transferase, family 2
KIM5_RS14950	COG2207	Transcriptional regulator
KIM5_RS14955	COG1064	alcohol dehydrogenase
KIM5_RS14960	COG1252	NADH dehydrogenase
KIM5_RS14970	COG1522	sequence-specific DNA binding
KIM5_RS14975	COG1794	racemase activity, acting on amino acids and derivatives
KIM5_RS14980	COG3385	transposase activity
KIM5_RS14985	COG1846	Transcriptional regulator
KIM5_RS14985	COG0456	acetyltransferase
KIM5_RS14990	COG1309	transcriptional regulator
KIM5_RS14995	COG2814	Major facilitator Superfamily
KIM5_RS15005	COG1733	regulation of RNA biosynthetic process
KIM5_RS15015	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KIM5_RS15025	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KIM5_RS15050	COG0668	transmembrane transport
KIM5_RS15100	COG0656	L-ascorbic acid biosynthetic process
KIM5_RS15110	COG0028	Belongs to the TPP enzyme family
KIM5_RS15120	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KIM5_RS15135	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KIM5_RS15140	COG0560	Phosphoserine phosphatase
KIM5_RS15145	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KIM5_RS15150	COG0330	HflC and HflK could
KIM5_RS15155	COG0330	HflC and HflK could
KIM5_RS15165	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KIM5_RS15195	COG0277	FAD linked oxidase domain protein
KIM5_RS15200	COG0667	Aldo Keto reductase
KIM5_RS15205	COG0583	DNA-binding transcription factor activity
KIM5_RS15210	COG3180	Ammonia monooxygenase
KIM5_RS15225	COG2885	chlorophyll binding
KIM5_RS15230	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KIM5_RS15235	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KIM5_RS15250	COG1487	ribonuclease activity
KIM5_RS15260	COG2719	SpoVR family
KIM5_RS15265	COG2718	Belongs to the UPF0229 family
KIM5_RS15270	COG2766	serine protein kinase
KIM5_RS15290	COG1335	isochorismatase
KIM5_RS15320	COG0006	proline dipeptidase activity
KIM5_RS15330	COG2264	protein methyltransferase activity
KIM5_RS15335	COG1999	signal sequence binding
KIM5_RS15340	COG2972	Histidine kinase
KIM5_RS15340	COG0840	transmembrane signaling receptor activity
KIM5_RS15345	COG0835	chemotaxis
KIM5_RS15365	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KIM5_RS15385	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KIM5_RS15395	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KIM5_RS15400	COG0849	cell division
KIM5_RS15405	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KIM5_RS15410	COG1181	Belongs to the D-alanine--D-alanine ligase family
KIM5_RS15420	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KIM5_RS15425	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KIM5_RS15430	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KIM5_RS15440	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KIM5_RS15445	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KIM5_RS15455	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KIM5_RS15470	COG0275	rRNA processing
KIM5_RS15475	COG2001	Belongs to the MraZ family
KIM5_RS15500	COG3023	N-Acetylmuramoyl-L-alanine amidase
KIM5_RS15505	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KIM5_RS15515	COG1280	lysine exporter protein (LysE YggA)
KIM5_RS15545	COG3757	hydrolase, family 25
KIM5_RS15560	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KIM5_RS15585	COG0697	spore germination
KIM5_RS15595	COG0028	Belongs to the TPP enzyme family
KIM5_RS15600	COG0251	oxidation-reduction process
KIM5_RS15615	COG1376	ErfK ybiS ycfS ynhG family protein
KIM5_RS15620	COG1192	Involved in chromosome partitioning
KIM5_RS15635	COG0174	glutamine synthetase
KIM5_RS15665	COG2011	ABC-type metal ion transport system permease component
KIM5_RS15670	COG3842	ATPase activity
KIM5_RS15680	COG0673	inositol 2-dehydrogenase activity
KIM5_RS15685	COG0395	ABC-type sugar transport system, permease component
KIM5_RS15690	COG1175	transmembrane transport
KIM5_RS15700	COG2971	BadF BadG BcrA BcrD
KIM5_RS15705	COG2188	Transcriptional regulator
KIM5_RS15730	COG4702	Belongs to the UPF0303 family
KIM5_RS15735	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KIM5_RS15745	COG0395	ABC-type sugar transport system, permease component
KIM5_RS15750	COG1176	ABC-type spermidine putrescine transport system, permease component I
KIM5_RS15760	COG3842	ATPase activity
KIM5_RS15765	COG2186	Transcriptional regulator
KIM5_RS15920	COG4397	Mu-like prophage major head subunit gpT
KIM5_RS15945	COG4383	Mu-like prophage protein gp29
KIM5_RS16045	COG2842	Transposition protein
KIM5_RS16050	COG2801	Transposase and inactivated derivatives
KIM5_RS16060	COG1475	DNA binding
KIM5_RS16120	COG2968	Membrane
KIM5_RS16135	COG0432	Pfam Uncharacterised protein family UPF0047
KIM5_RS16140	COG5507	3-demethylubiquinone-9 3-methyltransferase
KIM5_RS16165	COG0072	phenylalanine-tRNA ligase activity
KIM5_RS16165	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KIM5_RS16175	COG2207	Transcriptional regulator
KIM5_RS16175	COG1917	Cupin 2, conserved barrel domain protein
KIM5_RS16195	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KIM5_RS16220	COG0358	DNA primase activity
KIM5_RS16240	COG0505	Belongs to the CarA family
KIM5_RS16255	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KIM5_RS16275	COG0534	Mate efflux family protein
KIM5_RS16290	COG2321	neutral zinc metallopeptidase
KIM5_RS16305	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KIM5_RS16320	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KIM5_RS16330	COG1301	dicarboxylic acid transport
KIM5_RS16335	COG4191	Histidine kinase
KIM5_RS16340	COG2204	response regulator
KIM5_RS16345	COG1522	sequence-specific DNA binding
KIM5_RS16350	COG0492	ferredoxin-NADP+ reductase activity
KIM5_RS16355	COG0583	DNA-binding transcription factor activity
KIM5_RS16365	COG1902	pentaerythritol trinitrate reductase activity
KIM5_RS16380	COG0583	DNA-binding transcription factor activity
KIM5_RS16385	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KIM5_RS16395	COG0387	Pfam Sodium calcium exchanger
KIM5_RS16405	COG1442	glycosyl transferase family 8
KIM5_RS16440	COG2133	pyrroloquinoline quinone binding
KIM5_RS16460	COG1278	Cold shock
KIM5_RS16475	COG1733	regulation of RNA biosynthetic process
KIM5_RS16485	COG0745	RESPONSE REGULATOR receiver
KIM5_RS16490	COG1846	Transcriptional regulator
KIM5_RS16505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KIM5_RS16510	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KIM5_RS16530	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KIM5_RS16555	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KIM5_RS16570	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KIM5_RS16575	COG3300	MHYT domain
KIM5_RS16575	COG5001	Diguanylate cyclase
KIM5_RS16585	COG0193	aminoacyl-tRNA hydrolase activity
KIM5_RS16595	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KIM5_RS16620	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KIM5_RS16625	COG2857	Cytochrome c1
KIM5_RS16625	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KIM5_RS16645	COG1132	(ABC) transporter
KIM5_RS16655	COG1132	(ABC) transporter
KIM5_RS16675	COG0408	coproporphyrinogen oxidase activity
KIM5_RS16690	COG0617	tRNA 3'-terminal CCA addition
KIM5_RS16705	COG0714	Associated with various cellular activities
KIM5_RS16725	COG0454	-acetyltransferase
KIM5_RS16735	COG0435	Glutathione S-transferase
KIM5_RS16765	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KIM5_RS16770	COG3135	benzoate transporter
KIM5_RS16775	COG0740	serine-type endopeptidase activity
KIM5_RS16780	COG3416	Protein conserved in bacteria
KIM5_RS16785	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KIM5_RS16790	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KIM5_RS16805	COG0512	Glutamine amidotransferase of anthranilate synthase
KIM5_RS16805	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KIM5_RS16820	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KIM5_RS16825	COG3668	Plasmid stabilization system
KIM5_RS16830	COG2759	Belongs to the formate--tetrahydrofolate ligase family
KIM5_RS16845	COG2197	response regulator
KIM5_RS16865	COG1435	thymidine kinase activity
KIM5_RS16880	COG4175	Glycine betaine
KIM5_RS16895	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KIM5_RS16910	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KIM5_RS16925	COG0366	Alpha amylase catalytic
KIM5_RS16935	COG0601	transmembrane transport
KIM5_RS16940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KIM5_RS16950	COG4608	Belongs to the ABC transporter superfamily
KIM5_RS16960	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KIM5_RS16980	COG0657	acetylesterase activity
KIM5_RS16985	COG1846	Transcriptional regulator
KIM5_RS16990	COG1160	GTP binding
KIM5_RS17010	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
KIM5_RS17020	COG0723	plastoquinol--plastocyanin reductase activity
KIM5_RS17025	COG0024	Methionine aminopeptidase
KIM5_RS17045	COG4941	Belongs to the sigma-70 factor family
KIM5_RS17050	COG3795	YCII-related domain
KIM5_RS17055	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KIM5_RS17060	COG1028	Short-chain dehydrogenase reductase Sdr
KIM5_RS17070	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KIM5_RS17095	COG0583	DNA-binding transcription factor activity
KIM5_RS17110	COG0402	S-adenosylhomocysteine deaminase activity
KIM5_RS17115	COG3609	addiction module antidote protein, CC2985 family
KIM5_RS17135	COG2453	phosphatase
KIM5_RS17135	COG0671	phosphoesterase, PA-phosphatase related
KIM5_RS17140	COG2267	carboxylic ester hydrolase activity
KIM5_RS17145	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KIM5_RS17150	COG1842	Phage shock protein A
KIM5_RS17160	COG2268	Band 7 protein
KIM5_RS17170	COG2351	hydroxyisourate hydrolase activity
KIM5_RS17175	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
KIM5_RS17185	COG3648	Uricase
KIM5_RS17185	COG3195	allantoin biosynthetic process
KIM5_RS17200	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KIM5_RS17205	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KIM5_RS17205	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KIM5_RS17210	COG0018	arginyl-trna synthetase
KIM5_RS17215	COG0784	Response regulator, receiver
KIM5_RS17215	COG5002	protein histidine kinase activity
KIM5_RS17215	COG2205	protein histidine kinase activity
KIM5_RS17225	COG4335	DNA alkylation repair
KIM5_RS17230	COG0513	Belongs to the DEAD box helicase family
KIM5_RS17240	COG2308	Evidence 4 Homologs of previously reported genes of
KIM5_RS17265	COG0129	dihydroxy-acid dehydratase activity
KIM5_RS17270	COG1012	belongs to the aldehyde dehydrogenase family
KIM5_RS17280	COG4214	carbohydrate transport
KIM5_RS17290	COG4213	ABC transporter substrate-binding protein
KIM5_RS17310	COG0673	inositol 2-dehydrogenase activity
KIM5_RS17320	COG4213	ABC transporter substrate-binding protein
KIM5_RS17325	COG4214	carbohydrate transport
KIM5_RS17330	COG1129	ABC transporter
KIM5_RS17345	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KIM5_RS17345	COG2755	lipolytic protein G-D-S-L family
KIM5_RS17365	COG3108	Peptidase M15
KIM5_RS17405	COG1172	Belongs to the binding-protein-dependent transport system permease family
KIM5_RS17410	COG1129	ABC transporter
KIM5_RS17445	COG1216	Glycosyl transferase, family 2
KIM5_RS17450	COG0463	Glycosyl transferase, family 2
KIM5_RS17450	COG1216	Glycosyl transferase, family 2
KIM5_RS17455	COG1132	(ABC) transporter
KIM5_RS17460	COG1216	Glycosyl transferase, family 2
KIM5_RS17460	COG1442	glycosyl transferase family 8
KIM5_RS17500	COG1396	sequence-specific DNA binding
KIM5_RS17505	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KIM5_RS17525	COG0438	transferase activity, transferring glycosyl groups
KIM5_RS17545	COG1215	transferase activity, transferring glycosyl groups
KIM5_RS17555	COG2244	polysaccharide biosynthetic process
KIM5_RS17565	COG1215	transferase activity, transferring glycosyl groups
KIM5_RS17580	COG3594	Acyltransferase
KIM5_RS17600	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KIM5_RS17605	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
KIM5_RS17625	COG0489	protein tyrosine kinase activity
KIM5_RS17625	COG3206	protein involved in exopolysaccharide biosynthesis
KIM5_RS17650	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KIM5_RS17675	COG0400	carboxylic ester hydrolase activity
KIM5_RS17680	COG0346	lactoylglutathione lyase activity
KIM5_RS17685	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KIM5_RS17690	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KIM5_RS17695	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
KIM5_RS17695	COG0662	Cupin 2, conserved barrel domain protein
KIM5_RS17710	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KIM5_RS17720	COG1309	transcriptional regulator
KIM5_RS17725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KIM5_RS17730	COG1131	(ABC) transporter
KIM5_RS17735	COG0842	Transport permease protein
KIM5_RS17740	COG0842	Transport permease protein
KIM5_RS17775	COG2076	Multidrug Resistance protein
KIM5_RS17785	COG2346	COG2346, Truncated hemoglobins
KIM5_RS17825	COG3720	iron ion transport
KIM5_RS17830	COG4558	Periplasmic binding protein
KIM5_RS17835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KIM5_RS17840	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
KIM5_RS17865	COG0784	Response regulator, receiver
KIM5_RS17875	COG0493	'glutamate synthase
KIM5_RS17885	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KIM5_RS17910	COG0653	protein targeting
KIM5_RS17935	COG4251	negative regulation of phosphorylation
KIM5_RS17940	COG1309	transcriptional regulator
KIM5_RS17975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KIM5_RS17980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KIM5_RS17985	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KIM5_RS18005	COG0830	nickel cation binding
KIM5_RS18010	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
KIM5_RS18020	COG0804	urea catabolic process
KIM5_RS18025	COG1442	glycosyl transferase family 8
KIM5_RS18030	COG3755	Protein conserved in bacteria
KIM5_RS18035	COG0832	Belongs to the urease beta subunit family
KIM5_RS18040	COG3813	Protein conserved in bacteria
KIM5_RS18045	COG0831	urea catabolic process
KIM5_RS18050	COG0829	nickel cation binding
KIM5_RS18090	COG0784	Response regulator, receiver
KIM5_RS18090	COG2198	Histidine kinase
KIM5_RS18090	COG2205	protein histidine kinase activity
KIM5_RS18100	COG0683	leucine binding
KIM5_RS18205	COG0564	pseudouridine synthase activity
KIM5_RS18210	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KIM5_RS18220	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KIM5_RS18240	COG0129	dihydroxy-acid dehydratase activity
KIM5_RS18255	COG0657	acetylesterase activity
KIM5_RS18265	COG1028	Short-chain dehydrogenase reductase Sdr
KIM5_RS18280	COG2094	Belongs to the DNA glycosylase MPG family
KIM5_RS18290	COG1566	PFAM secretion protein HlyD family protein
KIM5_RS18305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KIM5_RS18325	COG1959	2 iron, 2 sulfur cluster binding
KIM5_RS18335	COG3622	Belongs to the hyi family
KIM5_RS18350	COG3842	ATPase activity
KIM5_RS18355	COG0395	ABC-type sugar transport system, permease component
KIM5_RS18360	COG1175	transmembrane transport
KIM5_RS18365	COG1653	transport
KIM5_RS18370	COG1846	Transcriptional regulator
KIM5_RS18370	COG1940	carbohydrate kinase activity
KIM5_RS18375	COG1653	transport
KIM5_RS18395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KIM5_RS18410	COG2244	polysaccharide biosynthetic process
KIM5_RS18415	COG0438	transferase activity, transferring glycosyl groups
KIM5_RS18435	COG0489	protein tyrosine kinase activity
KIM5_RS18445	COG1596	polysaccharide export
KIM5_RS18495	COG4993	Dehydrogenase
KIM5_RS18505	COG0839	Belongs to the complex I subunit 6 family
KIM5_RS18510	COG0713	ATP synthesis coupled electron transport
KIM5_RS18515	COG0651	ATP synthesis coupled electron transport
KIM5_RS18525	COG0651	ATP synthesis coupled electron transport
KIM5_RS18545	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KIM5_RS18550	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KIM5_RS18555	COG0649	NAD binding
KIM5_RS18585	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
KIM5_RS18640	COG0471	metal ion transport
KIM5_RS18640	COG3273	potassium ion transport
KIM5_RS18645	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KIM5_RS18650	COG1309	transcriptional regulator
KIM5_RS18655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KIM5_RS18660	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KIM5_RS18680	COG1176	ABC-type spermidine putrescine transport system, permease component I
KIM5_RS18685	COG1177	transmembrane transport
KIM5_RS18700	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KIM5_RS18705	COG1473	amidohydrolase
KIM5_RS18735	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KIM5_RS18760	COG3300	MHYT domain
KIM5_RS18760	COG5001	Diguanylate cyclase
KIM5_RS18770	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KIM5_RS18775	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
KIM5_RS18790	COG0683	leucine binding
KIM5_RS18800	COG0559	Belongs to the binding-protein-dependent transport system permease family
KIM5_RS18830	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KIM5_RS18835	COG3665	Urea carboxylase-associated protein
KIM5_RS18845	COG4770	biotin carboxylase activity
KIM5_RS18870	COG1116	anion transmembrane transporter activity
KIM5_RS18880	COG0402	S-adenosylhomocysteine deaminase activity
KIM5_RS18890	COG2249	NAD(P)H dehydrogenase (quinone) activity
KIM5_RS18915	COG1079	Belongs to the binding-protein-dependent transport system permease family
KIM5_RS18920	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KIM5_RS18925	COG1335	isochorismatase
KIM5_RS18930	COG3845	ABC transporter
KIM5_RS18935	COG1335	isochorismatase
KIM5_RS18965	COG0482	sulfurtransferase activity
KIM5_RS18975	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KIM5_RS18990	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KIM5_RS18995	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KIM5_RS19000	COG0037	tRNA processing
KIM5_RS19010	COG2885	chlorophyll binding
KIM5_RS19015	COG0823	Involved in the tonB-independent uptake of proteins
KIM5_RS19030	COG0848	biopolymer transport protein
KIM5_RS19040	COG0824	Thioesterase
KIM5_RS19065	COG1692	metallophosphoesterase
KIM5_RS19080	COG0217	transcriptional regulatory protein
KIM5_RS19085	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KIM5_RS19090	COG0840	transmembrane signaling receptor activity
KIM5_RS19095	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KIM5_RS19110	COG0632	four-way junction helicase activity
KIM5_RS19125	COG2255	four-way junction helicase activity
KIM5_RS19130	COG1408	metallophosphoesterase
KIM5_RS19140	COG2318	DinB family
KIM5_RS19150	COG0392	lysyltransferase activity
KIM5_RS19150	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KIM5_RS19160	COG0668	transmembrane transport
KIM5_RS19165	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KIM5_RS19185	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KIM5_RS19230	COG0126	phosphoglycerate kinase activity
KIM5_RS19235	COG3588	fructose-bisphosphate aldolase
KIM5_RS19240	COG0384	phenazine biosynthesis protein PhzF
KIM5_RS19265	COG0254	rRNA binding
KIM5_RS19270	COG1132	(ABC) transporter
KIM5_RS19285	COG3422	double-strand break repair
KIM5_RS19310	COG0483	inositol monophosphate 1-phosphatase activity
KIM5_RS19315	COG2201	protein-glutamate methylesterase activity
KIM5_RS19325	COG0835	chemotaxis
KIM5_RS19330	COG0840	transmembrane signaling receptor activity
KIM5_RS19340	COG0835	chemotaxis
KIM5_RS19345	COG2198	Histidine kinase
KIM5_RS19345	COG0643	Histidine kinase
KIM5_RS19380	COG0640	Transcriptional regulator
KIM5_RS19385	COG1522	sequence-specific DNA binding
KIM5_RS19390	COG0460	homoserine dehydrogenase
KIM5_RS19395	COG1012	belongs to the aldehyde dehydrogenase family
KIM5_RS19405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KIM5_RS19425	COG0626	cystathionine gamma-synthase activity
KIM5_RS19435	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KIM5_RS19440	COG1522	sequence-specific DNA binding
KIM5_RS19455	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KIM5_RS19460	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KIM5_RS19465	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KIM5_RS19470	COG0457	Tetratricopeptide repeat
KIM5_RS19490	COG4221	oxidoreductase activity
KIM5_RS19500	COG0583	DNA-binding transcription factor activity
KIM5_RS19505	COG1942	4-Oxalocrotonate Tautomerase
KIM5_RS19515	COG1280	lysine exporter protein (LysE YggA)
KIM5_RS19520	COG0469	pyruvate kinase activity
KIM5_RS19540	COG3750	Belongs to the UPF0335 family
KIM5_RS19545	COG3108	Peptidase M15
KIM5_RS19560	COG0512	Glutamine amidotransferase of anthranilate synthase
KIM5_RS19560	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KIM5_RS19575	COG5310	Homospermidine synthase
KIM5_RS19585	COG0737	Belongs to the 5'-nucleotidase family
KIM5_RS19590	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KIM5_RS19595	COG0330	HflC and HflK could
KIM5_RS19615	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KIM5_RS19620	COG2951	lytic endotransglycosylase activity
KIM5_RS19635	COG0070	glutamate synthase
KIM5_RS19635	COG0067	glutamate synthase
KIM5_RS19635	COG0069	glutamate synthase activity
KIM5_RS19655	COG0071	Belongs to the small heat shock protein (HSP20) family
KIM5_RS19750	COG1473	amidohydrolase
KIM5_RS19765	COG4172	Belongs to the ABC transporter superfamily
KIM5_RS19775	COG0601	transmembrane transport
KIM5_RS19780	COG0583	DNA-binding transcription factor activity
KIM5_RS19820	COG2308	Evidence 4 Homologs of previously reported genes of
KIM5_RS19820	COG2307	Protein conserved in bacteria
KIM5_RS19835	COG0058	SHG alpha-glucan phosphorylase activity
KIM5_RS19840	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KIM5_RS19845	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KIM5_RS19850	COG0297	glycogen (starch) synthase activity
KIM5_RS19855	COG0033	Phosphoglucomutase
KIM5_RS19860	COG1523	belongs to the glycosyl hydrolase 13 family
KIM5_RS19880	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KIM5_RS19880	COG0446	pyridine nucleotide-disulphide oxidoreductase
KIM5_RS19890	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KIM5_RS19910	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KIM5_RS19960	COG5001	Diguanylate cyclase
KIM5_RS19975	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
KIM5_RS19985	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KIM5_RS19990	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KIM5_RS19995	COG1609	Transcriptional regulator
KIM5_RS20000	COG1846	Transcriptional regulator
KIM5_RS20010	COG0523	cobalamin synthesis protein
KIM5_RS20025	COG1045	serine acetyltransferase
KIM5_RS20045	COG0583	DNA-binding transcription factor activity
KIM5_RS20075	COG0800	Aldolase
KIM5_RS20080	COG2954	triphosphatase activity
KIM5_RS20095	COG1054	Belongs to the UPF0176 family
KIM5_RS20115	COG0673	inositol 2-dehydrogenase activity
KIM5_RS20125	COG1879	ABC-type sugar transport system periplasmic component
KIM5_RS20130	COG1172	Belongs to the binding-protein-dependent transport system permease family
KIM5_RS20135	COG1129	ABC transporter
KIM5_RS20140	COG1609	Transcriptional regulator
KIM5_RS20145	COG2115	Belongs to the xylose isomerase family
KIM5_RS20150	COG1070	Carbohydrate kinase
KIM5_RS20170	COG1309	transcriptional regulator
KIM5_RS20180	COG1253	flavin adenine dinucleotide binding
KIM5_RS20185	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KIM5_RS20190	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KIM5_RS20200	COG0583	DNA-binding transcription factor activity
KIM5_RS20205	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KIM5_RS20210	COG3842	ATPase activity
KIM5_RS20215	COG1176	ABC-type spermidine putrescine transport system, permease component I
KIM5_RS20220	COG1177	transmembrane transport
KIM5_RS20245	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KIM5_RS20265	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KIM5_RS20315	COG1175	transmembrane transport
KIM5_RS20335	COG1940	carbohydrate kinase activity
KIM5_RS20360	COG1764	response to oxidative stress
KIM5_RS20365	COG1028	Short-chain dehydrogenase reductase Sdr
KIM5_RS20380	COG1129	ABC transporter
KIM5_RS20390	COG2186	Transcriptional regulator
KIM5_RS20395	COG4948	Mandelate Racemase Muconate Lactonizing
KIM5_RS20405	COG1028	Short-chain dehydrogenase reductase Sdr
KIM5_RS20420	COG1028	Short-chain dehydrogenase reductase Sdr
KIM5_RS20435	COG3842	ATPase activity
KIM5_RS20440	COG0395	ABC-type sugar transport system, permease component
KIM5_RS20445	COG1175	transmembrane transport
KIM5_RS20450	COG1653	transport
KIM5_RS20455	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KIM5_RS20460	COG0720	synthase
KIM5_RS20465	COG0602	queuosine metabolic process
KIM5_RS20475	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KIM5_RS20490	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KIM5_RS20515	COG1012	belongs to the aldehyde dehydrogenase family
KIM5_RS20525	COG1028	Short-chain dehydrogenase reductase Sdr
KIM5_RS20530	COG0387	Pfam Sodium calcium exchanger
KIM5_RS20575	COG0542	response to heat
KIM5_RS20585	COG2890	protein-(glutamine-N5) methyltransferase activity
KIM5_RS20590	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KIM5_RS20600	COG0527	aspartate kinase activity
KIM5_RS20605	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KIM5_RS20615	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KIM5_RS20630	COG2226	methyltransferase
KIM5_RS20645	COG0494	nUDIX hydrolase
KIM5_RS20655	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KIM5_RS20660	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KIM5_RS20665	COG0653	protein targeting
KIM5_RS20680	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KIM5_RS20685	COG0667	Aldo Keto reductase
KIM5_RS20715	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KIM5_RS20715	COG4651	solute:proton antiporter activity
KIM5_RS20745	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KIM5_RS20755	COG0300	oxidoreductase activity
KIM5_RS20775	COG2086	electron transfer activity
KIM5_RS20780	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KIM5_RS20785	COG1250	3-hydroxyacyl-CoA dehydrogenase
KIM5_RS20790	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KIM5_RS20795	COG0165	Argininosuccinate lyase
KIM5_RS20820	COG0037	tRNA processing
KIM5_RS20820	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KIM5_RS20840	COG2884	Cell division ATP-binding protein ftsE
KIM5_RS20860	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
KIM5_RS20875	COG0287	Prephenate dehydrogenase
KIM5_RS20880	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KIM5_RS20885	COG2226	methyltransferase
KIM5_RS20890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KIM5_RS20915	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KIM5_RS20925	COG0563	adenylate kinase activity
KIM5_RS20955	COG4536	flavin adenine dinucleotide binding
KIM5_RS20960	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KIM5_RS20965	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KIM5_RS20975	COG4974	Belongs to the 'phage' integrase family
KIM5_RS20980	COG0825	malonyl-CoA metabolic process
KIM5_RS20985	COG3034	peptidoglycan biosynthetic process
KIM5_RS20995	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KIM5_RS21010	COG2186	Transcriptional regulator
KIM5_RS21015	COG0523	cobalamin synthesis protein
KIM5_RS21020	COG1686	Belongs to the peptidase S11 family
KIM5_RS21060	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KIM5_RS21080	COG1175	transmembrane transport
KIM5_RS21095	COG0156	8-amino-7-oxononanoate synthase activity
KIM5_RS21105	COG0729	surface antigen
KIM5_RS21120	COG0010	Belongs to the arginase family
KIM5_RS21125	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KIM5_RS21130	COG0835	chemotaxis
KIM5_RS21140	COG2223	nitrite transmembrane transporter activity
KIM5_RS21150	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KIM5_RS21155	COG3383	formate dehydrogenase (NAD+) activity
KIM5_RS21170	COG0583	DNA-binding transcription factor activity
KIM5_RS21175	COG0640	Transcriptional regulator
KIM5_RS21180	COG1028	Short-chain dehydrogenase reductase Sdr
KIM5_RS21185	COG0789	Transcriptional regulator
KIM5_RS21190	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KIM5_RS21195	COG1116	anion transmembrane transporter activity
KIM5_RS21200	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KIM5_RS21215	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KIM5_RS21225	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KIM5_RS21230	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KIM5_RS21235	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KIM5_RS21240	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KIM5_RS21255	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KIM5_RS21270	COG4974	Belongs to the 'phage' integrase family
KIM5_RS21285	COG1280	lysine exporter protein (LysE YggA)
KIM5_RS21290	COG1028	Short-chain dehydrogenase reductase Sdr
KIM5_RS21305	COG0508	dehydrogenase complex catalyzes the overall conversion of
KIM5_RS21320	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KIM5_RS21325	COG0045	succinate-CoA ligase (ADP-forming) activity
KIM5_RS21330	COG0039	L-malate dehydrogenase activity
KIM5_RS21335	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KIM5_RS21340	COG2845	Protein of unknown function (DUF459)
KIM5_RS21385	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KIM5_RS21390	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KIM5_RS21395	COG0181	hydroxymethylbilane synthase activity
KIM5_RS21420	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KIM5_RS21435	COG1872	DUF167
KIM5_RS21440	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KIM5_RS21450	COG1217	gtp-binding protein TYPA
KIM5_RS21455	COG0339	signal peptide processing
KIM5_RS21475	COG1764	response to oxidative stress
KIM5_RS21485	COG0583	DNA-binding transcription factor activity
KIM5_RS21510	COG3264	Mechanosensitive ion channel
KIM5_RS21510	COG1511	domain protein
KIM5_RS21515	COG0137	argininosuccinate synthase activity
KIM5_RS21535	COG4120	Belongs to the binding-protein-dependent transport system permease family
KIM5_RS21545	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KIM5_RS21570	COG1595	DNA-templated transcription, initiation
KIM5_RS21580	COG2154	pterin-4-alpha-carbinolamine dehydratase
KIM5_RS21585	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KIM5_RS21590	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KIM5_RS21600	COG4181	ATPase activity
KIM5_RS21610	COG0670	Belongs to the BI1 family
KIM5_RS21630	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KIM5_RS21635	COG4133	protoheme IX ABC transporter activity
KIM5_RS21645	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KIM5_RS21650	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KIM5_RS21670	COG2917	probably involved in intracellular septation
KIM5_RS21675	COG0552	protein localization to endoplasmic reticulum
KIM5_RS21680	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KIM5_RS21685	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KIM5_RS21700	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KIM5_RS21705	COG0287	Prephenate dehydrogenase
KIM5_RS21705	COG1605	Chorismate mutase
KIM5_RS21710	COG0228	four-way junction DNA binding
KIM5_RS21715	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KIM5_RS21720	COG0336	Belongs to the RNA methyltransferase TrmD family
KIM5_RS21725	COG0335	large ribosomal subunit rRNA binding
KIM5_RS21735	COG0765	amino acid transport
KIM5_RS21745	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KIM5_RS21750	COG0656	L-ascorbic acid biosynthetic process
KIM5_RS21760	COG0745	RESPONSE REGULATOR receiver
KIM5_RS21775	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KIM5_RS21780	COG1674	ftsk spoiiie
KIM5_RS21785	COG0004	ammonium transporteR
KIM5_RS21790	COG0347	Belongs to the P(II) protein family
KIM5_RS21800	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KIM5_RS21805	COG2835	tetraacyldisaccharide 4'-kinase activity
KIM5_RS21865	COG1129	ABC transporter
KIM5_RS21870	COG4211	Belongs to the binding-protein-dependent transport system permease family
KIM5_RS21885	COG0601	transmembrane transport
KIM5_RS21890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KIM5_RS21895	COG0444	Belongs to the ABC transporter superfamily
KIM5_RS21910	COG3459	Glycosyltransferase 36 associated
KIM5_RS21925	COG1132	(ABC) transporter
KIM5_RS21935	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KIM5_RS21940	COG0431	NADPH-dependent FMN reductase
KIM5_RS21945	COG1126	abc transporter atp-binding protein
KIM5_RS21950	COG0765	amino acid transport
KIM5_RS21955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KIM5_RS21960	COG1349	DNA-binding transcription factor activity
KIM5_RS21965	COG2223	nitrite transmembrane transporter activity
KIM5_RS21970	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KIM5_RS21975	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KIM5_RS21980	COG0142	geranyltranstransferase activity
KIM5_RS21985	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KIM5_RS22000	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KIM5_RS22010	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
KIM5_RS22015	COG0183	Belongs to the thiolase family
KIM5_RS22045	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KIM5_RS22050	COG1329	Transcriptional regulator
KIM5_RS22055	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KIM5_RS22065	COG0477	Major facilitator Superfamily
KIM5_RS22080	COG0488	(ABC) transporter
KIM5_RS22085	COG4178	(ABC) transporter
KIM5_RS22090	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
KIM5_RS22100	COG2188	Transcriptional regulator
KIM5_RS22105	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KIM5_RS22110	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KIM5_RS22115	COG4821	SIS domain
KIM5_RS22120	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KIM5_RS22135	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KIM5_RS22145	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KIM5_RS22160	COG0438	transferase activity, transferring glycosyl groups
KIM5_RS22170	COG0438	transferase activity, transferring glycosyl groups
KIM5_RS22185	COG5383	Protein conserved in bacteria
KIM5_RS22190	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KIM5_RS22195	COG1012	belongs to the aldehyde dehydrogenase family
KIM5_RS22210	COG3842	ATPase activity
KIM5_RS22240	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KIM5_RS22245	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KIM5_RS22265	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KIM5_RS22270	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KIM5_RS22275	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KIM5_RS22280	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KIM5_RS22285	COG0725	ABC transporter, periplasmic molybdate-binding protein
KIM5_RS22290	COG4149	molybdate abc transporter
KIM5_RS22295	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KIM5_RS22305	COG0799	negative regulation of ribosome biogenesis
KIM5_RS22310	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KIM5_RS22320	COG0793	Belongs to the peptidase S41A family
KIM5_RS22330	COG0494	nUDIX hydrolase
KIM5_RS22345	COG0587	DNA-directed DNA polymerase activity
KIM5_RS22365	COG2301	Belongs to the HpcH HpaI aldolase family
KIM5_RS22380	COG0066	3-isopropylmalate dehydratase activity
KIM5_RS22390	COG0473	3-isopropylmalate dehydrogenase activity
KIM5_RS22395	COG0671	phosphoesterase, PA-phosphatase related
KIM5_RS22410	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KIM5_RS22425	COG0288	reversible hydration of carbon dioxide
KIM5_RS22440	COG2902	Dehydrogenase
KIM5_RS22445	COG2270	Major facilitator Superfamily
KIM5_RS22450	COG0138	bifunctional purine biosynthesis protein purh
KIM5_RS22460	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KIM5_RS22460	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KIM5_RS22465	COG0501	Belongs to the peptidase M48B family
KIM5_RS22475	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KIM5_RS22500	COG0495	leucyl-tRNA aminoacylation
KIM5_RS22525	COG0357	Ribosomal RNA small subunit methyltransferase G
KIM5_RS22530	COG0445	tRNA wobble uridine modification
KIM5_RS22535	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KIM5_RS22540	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KIM5_RS22545	COG1981	membrane
KIM5_RS22550	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KIM5_RS22575	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KIM5_RS22600	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KIM5_RS22630	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KIM5_RS22635	COG0210	DNA helicase
KIM5_RS22765	COG0784	Response regulator, receiver
KIM5_RS22765	COG4191	Histidine kinase
KIM5_RS22795	COG1396	sequence-specific DNA binding
KIM5_RS22875	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KIM5_RS22930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KIM5_RS22955	COG3436	PFAM IS66 Orf2 family protein
KIM5_RS22960	COG3436	PFAM IS66 Orf2 family protein
KIM5_RS22980	COG2132	Multicopper oxidase
KIM5_RS22990	COG1028	Short-chain dehydrogenase reductase Sdr
KIM5_RS22995	COG0300	oxidoreductase activity
KIM5_RS23000	COG4221	oxidoreductase activity
KIM5_RS23005	COG0583	DNA-binding transcription factor activity
KIM5_RS23040	COG1484	DNA-dependent DNA replication
KIM5_RS23045	COG4584	PFAM Integrase catalytic
KIM5_RS23100	COG4669	(LipO)protein
KIM5_RS23120	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KIM5_RS23125	COG4790	Type iii secretion
KIM5_RS23130	COG1987	bacterial-type flagellum assembly
KIM5_RS23135	COG4791	protein targeting
KIM5_RS23140	COG4792	protein secretion
KIM5_RS23145	COG5297	Belongs to the glycosyl hydrolase family 6
KIM5_RS23150	COG4789	Type iii secretion
KIM5_RS23170	COG1396	sequence-specific DNA binding
KIM5_RS23195	COG1358	cellular component organization or biogenesis
KIM5_RS23260	COG0596	Alpha beta hydrolase
KIM5_RS23265	COG1879	ABC-type sugar transport system periplasmic component
KIM5_RS23270	COG1129	ABC transporter
KIM5_RS23275	COG1172	Belongs to the binding-protein-dependent transport system permease family
KIM5_RS23280	COG1172	Belongs to the binding-protein-dependent transport system permease family
KIM5_RS23310	COG0840	transmembrane signaling receptor activity
KIM5_RS23310	COG2972	Histidine kinase
KIM5_RS23335	COG2972	Histidine kinase
KIM5_RS23335	COG0840	transmembrane signaling receptor activity
KIM5_RS23340	COG4213	ABC transporter substrate-binding protein
KIM5_RS23355	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KIM5_RS23360	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KIM5_RS23370	COG2186	Transcriptional regulator
KIM5_RS23380	COG3328	transposase activity
KIM5_RS23385	COG1028	Short-chain dehydrogenase reductase Sdr
KIM5_RS23390	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KIM5_RS23395	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KIM5_RS23405	COG1879	ABC-type sugar transport system periplasmic component
KIM5_RS23410	COG0436	Aminotransferase
KIM5_RS23420	COG0431	NADPH-dependent FMN reductase
KIM5_RS23425	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KIM5_RS23425	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KIM5_RS23445	COG1879	ABC-type sugar transport system periplasmic component
KIM5_RS23450	COG1129	ABC transporter
KIM5_RS23455	COG1172	Belongs to the binding-protein-dependent transport system permease family
KIM5_RS23475	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KIM5_RS23485	COG0840	transmembrane signaling receptor activity
KIM5_RS23495	COG0459	protein refolding
KIM5_RS23525	COG3838	Conjugal transfer protein Trbc
KIM5_RS23530	COG3702	type iv secretory pathway
KIM5_RS23535	COG3451	type IV secretory pathway VirB4
KIM5_RS23550	COG3704	protein secretion by the type IV secretion system
KIM5_RS23560	COG3736	Type IV secretory pathway, component VirB8
KIM5_RS23565	COG3504	Conjugal transfer protein
KIM5_RS23570	COG2948	multi-organism process
KIM5_RS23575	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
KIM5_RS23615	COG3831	ATPase activity
KIM5_RS23630	COG2161	toxin-antitoxin pair type II binding
KIM5_RS23635	COG3505	Type IV secretory pathway VirD4
KIM5_RS23685	COG1396	sequence-specific DNA binding
KIM5_RS23690	COG2843	Capsule synthesis protein
KIM5_RS23730	COG4372	Transposase
KIM5_RS23755	COG5490	Phasin protein
KIM5_RS23900	COG0535	radical SAM domain protein
KIM5_RS23915	COG1028	Short-chain dehydrogenase reductase Sdr
KIM5_RS23920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KIM5_RS23965	COG2801	Transposase and inactivated derivatives
KIM5_RS24000	COG1433	Dinitrogenase iron-molybdenum cofactor
KIM5_RS24005	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
KIM5_RS24010	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
KIM5_RS24015	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
KIM5_RS24020	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
KIM5_RS24060	COG2124	cytochrome p450
KIM5_RS24075	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KIM5_RS24085	COG0316	Belongs to the HesB IscA family
KIM5_RS24095	COG1104	cysteine desulfurase activity
KIM5_RS24110	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KIM5_RS24115	COG0644	oxidoreductase
KIM5_RS24130	COG0535	radical SAM domain protein
KIM5_RS24135	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KIM5_RS24140	COG5554	nitrogen fixation
KIM5_RS24145	COG5554	nitrogen fixation
KIM5_RS24175	COG0142	geranyltranstransferase activity
KIM5_RS24200	COG1304	FMN binding
KIM5_RS24210	COG1657	PFAM Prenyltransferase squalene oxidase
KIM5_RS24220	COG2124	cytochrome p450
KIM5_RS24225	COG1028	Short-chain dehydrogenase reductase Sdr
KIM5_RS24265	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
KIM5_RS24270	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KIM5_RS24280	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KIM5_RS24315	COG2192	nodulation
KIM5_RS24370	COG2192	nodulation
KIM5_RS24375	COG2192	nodulation
KIM5_RS24530	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KIM5_RS24550	COG5490	Phasin protein
KIM5_RS24565	COG3383	formate dehydrogenase (NAD+) activity
KIM5_RS24570	COG5420	small protein containing a coiled-coil domain
KIM5_RS24580	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
KIM5_RS24585	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
KIM5_RS24590	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
KIM5_RS24650	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KIM5_RS24675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KIM5_RS24700	COG2801	Transposase and inactivated derivatives
KIM5_RS24710	COG3436	PFAM IS66 Orf2 family protein
KIM5_RS24715	COG4372	Transposase
KIM5_RS24735	COG2274	protein secretion by the type I secretion system
KIM5_RS24740	COG2801	Transposase and inactivated derivatives
KIM5_RS24760	COG3594	Acyltransferase
KIM5_RS24765	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KIM5_RS24770	COG5490	Phasin protein
KIM5_RS24780	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KIM5_RS24800	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KIM5_RS24815	COG1192	Involved in chromosome partitioning
KIM5_RS24820	COG1475	DNA binding
KIM5_RS24825	COG0640	Transcriptional regulator
KIM5_RS24835	COG0670	Belongs to the BI1 family
KIM5_RS24875	COG4953	penicillin-binding protein 1C
KIM5_RS24885	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KIM5_RS24890	COG3034	peptidoglycan biosynthetic process
KIM5_RS24905	COG2814	Major facilitator Superfamily
KIM5_RS24910	COG1609	Transcriptional regulator
KIM5_RS24925	COG1132	(ABC) transporter
KIM5_RS24935	COG1132	(ABC) transporter
KIM5_RS24965	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KIM5_RS24970	COG1845	cytochrome c oxidase, subunit III
KIM5_RS24975	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KIM5_RS24980	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KIM5_RS25000	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KIM5_RS25000	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KIM5_RS25025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KIM5_RS25035	COG4166	transmembrane transport
KIM5_RS25065	COG1959	2 iron, 2 sulfur cluster binding
KIM5_RS25075	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
KIM5_RS25125	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KIM5_RS25130	COG3485	protocatechuate 3,4-dioxygenase
KIM5_RS25135	COG3485	protocatechuate 3,4-dioxygenase
KIM5_RS25140	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KIM5_RS25145	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KIM5_RS25150	COG0583	DNA-binding transcription factor activity
KIM5_RS25160	COG5654	RES domain protein
KIM5_RS25180	COG0484	heat shock protein binding
KIM5_RS25190	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KIM5_RS25200	COG2986	histidine ammonia-lyase
KIM5_RS25205	COG1228	amidohydrolase
KIM5_RS25210	COG0402	S-adenosylhomocysteine deaminase activity
KIM5_RS25215	COG2188	Transcriptional regulator
KIM5_RS25220	COG2188	Transcriptional regulator
KIM5_RS25245	COG2986	histidine ammonia-lyase
KIM5_RS25255	COG0671	phosphoesterase, PA-phosphatase related
KIM5_RS25265	COG0583	DNA-binding transcription factor activity
KIM5_RS25280	COG3474	cytochrome
KIM5_RS25325	COG1486	melibiose metabolic process
KIM5_RS25330	COG0747	negative chemotaxis
KIM5_RS25335	COG0601	transmembrane transport
KIM5_RS25340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KIM5_RS25345	COG4172	Belongs to the ABC transporter superfamily
KIM5_RS25350	COG1486	melibiose metabolic process
KIM5_RS25370	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KIM5_RS25435	COG2963	transposase activity
KIM5_RS25445	COG4372	Transposase
KIM5_RS25515	COG0793	Belongs to the peptidase S41A family
KIM5_RS25530	COG2199	diguanylate cyclase activity
KIM5_RS25560	COG1672	PFAM Archaeal ATPase
KIM5_RS25560	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
KIM5_RS25565	COG0318	PFAM AMP-dependent synthetase and ligase
KIM5_RS25625	COG1028	Short-chain dehydrogenase reductase Sdr
KIM5_RS25630	COG3842	ATPase activity
KIM5_RS25640	COG1063	alcohol dehydrogenase
KIM5_RS25665	COG2207	Transcriptional regulator
KIM5_RS25710	COG4608	Belongs to the ABC transporter superfamily
KIM5_RS25715	COG0444	Belongs to the ABC transporter superfamily
KIM5_RS25720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KIM5_RS25765	COG1414	Transcriptional regulator
KIM5_RS25775	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KIM5_RS25780	COG0183	Belongs to the thiolase family
KIM5_RS25795	COG1309	transcriptional regulator
KIM5_RS25805	COG0765	amino acid transport
KIM5_RS25815	COG1126	abc transporter atp-binding protein
KIM5_RS25820	COG0673	inositol 2-dehydrogenase activity
KIM5_RS25825	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KIM5_RS25895	COG1573	uracil-dna glycosylase
KIM5_RS25950	COG1238	metal cluster binding
KIM5_RS25970	COG3842	ATPase activity
KIM5_RS25975	COG1840	ABC-type Fe3 transport system, periplasmic component
KIM5_RS25980	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KIM5_RS25985	COG2186	Transcriptional regulator
KIM5_RS25990	COG0626	cystathionine gamma-synthase activity
KIM5_RS25995	COG2182	Extracellular solute-binding protein
KIM5_RS26005	COG0395	ABC-type sugar transport system, permease component
KIM5_RS26010	COG3842	ATPase activity
KIM5_RS26020	COG3409	Peptidoglycan-binding domain 1 protein
KIM5_RS26020	COG3773	Cell wall hydrolase
KIM5_RS26025	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KIM5_RS26030	COG4208	sulfate ABC transporter
KIM5_RS26040	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KIM5_RS26060	COG2205	protein histidine kinase activity
KIM5_RS26065	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
KIM5_RS26070	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
KIM5_RS26075	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KIM5_RS26095	COG1063	alcohol dehydrogenase
KIM5_RS26165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KIM5_RS26175	COG1120	ATPase activity
KIM5_RS26180	COG4774	siderophore transport
KIM5_RS26210	COG1172	Belongs to the binding-protein-dependent transport system permease family
KIM5_RS26230	COG3347	Dehydrogenase
KIM5_RS26230	COG1028	Short-chain dehydrogenase reductase Sdr
KIM5_RS26240	COG4952	isomerase
KIM5_RS26245	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KIM5_RS26255	COG3964	amidohydrolase
KIM5_RS26260	COG4691	Plasmid stability protein
KIM5_RS26270	COG1028	Short-chain dehydrogenase reductase Sdr
KIM5_RS26320	COG3119	arylsulfatase activity
KIM5_RS26325	COG0583	DNA-binding transcription factor activity
KIM5_RS26335	COG3836	Belongs to the HpcH HpaI aldolase family
KIM5_RS26350	COG0444	Belongs to the ABC transporter superfamily
KIM5_RS26355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KIM5_RS26370	COG1472	Belongs to the glycosyl hydrolase 3 family
KIM5_RS26385	COG0352	thiamine-phosphate diphosphorylase activity
KIM5_RS26400	COG0747	negative chemotaxis
KIM5_RS26405	COG0601	transmembrane transport
KIM5_RS26420	COG1921	L-seryl-tRNASec selenium transferase activity
KIM5_RS26430	COG3257	ureidoglycine aminohydrolase activity
KIM5_RS26460	COG2186	Transcriptional regulator
KIM5_RS26475	COG1027	Aspartate ammonia-lyase
KIM5_RS26495	COG1309	transcriptional regulator
KIM5_RS26500	COG2801	Transposase and inactivated derivatives
KIM5_RS26525	COG0154	amidase activity
KIM5_RS26545	COG0683	leucine binding
KIM5_RS26550	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KIM5_RS26565	COG3618	amidohydrolase
KIM5_RS26570	COG1879	ABC-type sugar transport system periplasmic component
KIM5_RS26575	COG1172	Belongs to the binding-protein-dependent transport system permease family
KIM5_RS26580	COG1129	ABC transporter
KIM5_RS26585	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KIM5_RS26590	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KIM5_RS26595	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KIM5_RS26600	COG3958	Transketolase
KIM5_RS26605	COG3959	Transketolase, thiamine diphosphate binding domain
KIM5_RS26610	COG1028	Short-chain dehydrogenase reductase Sdr
KIM5_RS26615	COG0583	DNA-binding transcription factor activity
KIM5_RS26655	COG0673	inositol 2-dehydrogenase activity
KIM5_RS26665	COG0395	ABC-type sugar transport system, permease component
KIM5_RS26675	COG3842	ATPase activity
KIM5_RS26685	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
KIM5_RS26690	COG2155	Conserved Protein
KIM5_RS26715	COG3842	ATPase activity
KIM5_RS26735	COG2207	Transcriptional regulator
KIM5_RS26745	COG0583	DNA-binding transcription factor activity
KIM5_RS26755	COG1028	Short-chain dehydrogenase reductase Sdr
KIM5_RS26780	COG1737	Transcriptional regulator
KIM5_RS26785	COG1028	Short-chain dehydrogenase reductase Sdr
KIM5_RS26825	COG2186	Transcriptional regulator
KIM5_RS26830	COG1028	Short-chain dehydrogenase reductase Sdr
KIM5_RS26835	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
KIM5_RS26860	COG0667	Aldo Keto reductase
KIM5_RS26870	COG2894	cell division
KIM5_RS26875	COG0850	regulation of cytokinetic process
KIM5_RS26890	COG0069	glutamate synthase activity
KIM5_RS26895	COG2218	PFAM glutamate synthase alpha subunit domain protein
KIM5_RS26900	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KIM5_RS26910	COG4977	sequence-specific DNA binding
KIM5_RS26915	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KIM5_RS26920	COG4311	Sarcosine oxidase, delta subunit
KIM5_RS26925	COG0446	pyridine nucleotide-disulphide oxidoreductase
KIM5_RS26925	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KIM5_RS26935	COG4650	regulator
KIM5_RS26960	COG1309	transcriptional regulator
KIM5_RS26975	COG2020	methyltransferase activity
KIM5_RS26980	COG4948	Mandelate Racemase Muconate Lactonizing
KIM5_RS26985	COG1028	Short-chain dehydrogenase reductase Sdr
KIM5_RS27000	COG1396	sequence-specific DNA binding
KIM5_RS27030	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KIM5_RS27035	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KIM5_RS27045	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KIM5_RS27065	COG1609	Transcriptional regulator
KIM5_RS27115	COG1192	Involved in chromosome partitioning
KIM5_RS27120	COG1475	DNA binding
KIM5_RS27125	COG1414	Transcriptional regulator
KIM5_RS27155	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
KIM5_RS27210	COG1028	Short-chain dehydrogenase reductase Sdr
KIM5_RS27215	COG0583	DNA-binding transcription factor activity
KIM5_RS27225	COG1733	regulation of RNA biosynthetic process
KIM5_RS27230	COG3321	synthase
KIM5_RS27230	COG1028	Short-chain dehydrogenase reductase Sdr
KIM5_RS27230	COG0604	alcohol dehydrogenase
KIM5_RS27240	COG0318	PFAM AMP-dependent synthetase and ligase
KIM5_RS27245	COG0183	Belongs to the thiolase family
KIM5_RS27305	COG1609	Transcriptional regulator
KIM5_RS27310	COG1653	transport
KIM5_RS27320	COG1175	transmembrane transport
KIM5_RS27325	COG0395	ABC-type sugar transport system, permease component
KIM5_RS27335	COG3685	Protein conserved in bacteria
KIM5_RS27355	COG3685	Protein conserved in bacteria
KIM5_RS27400	COG3920	Histidine kinase
KIM5_RS27400	COG2202	Pas domain
KIM5_RS27425	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KIM5_RS27435	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KIM5_RS27440	COG1063	alcohol dehydrogenase
KIM5_RS27460	COG2201	protein-glutamate methylesterase activity
KIM5_RS27490	COG3706	GGDEF domain
KIM5_RS27495	COG3920	Histidine kinase
KIM5_RS27500	COG4191	Histidine kinase
KIM5_RS27500	COG0784	Response regulator, receiver
KIM5_RS27535	COG1609	Transcriptional regulator
KIM5_RS27540	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KIM5_RS27545	COG1028	Short-chain dehydrogenase reductase Sdr
KIM5_RS27550	COG3842	ATPase activity
KIM5_RS27560	COG1175	transmembrane transport
KIM5_RS27565	COG0395	ABC-type sugar transport system, permease component
KIM5_RS27575	COG1129	ABC transporter
KIM5_RS27580	COG1172	Belongs to the binding-protein-dependent transport system permease family
KIM5_RS27605	COG1609	Transcriptional regulator
KIM5_RS27625	COG0714	Associated with various cellular activities
KIM5_RS27630	COG2425	protein containing a von Willebrand factor type A (vWA) domain
KIM5_RS27635	COG3552	Protein containing von Willebrand factor type A (VWA) domain
KIM5_RS27650	COG2207	Transcriptional regulator
KIM5_RS27650	COG1917	Cupin 2, conserved barrel domain protein
KIM5_RS27655	COG5001	Diguanylate cyclase
KIM5_RS27655	COG3300	MHYT domain
KIM5_RS27665	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KIM5_RS27680	COG1175	transmembrane transport
KIM5_RS27685	COG3833	ABC-type maltose transport systems, permease component
KIM5_RS27690	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KIM5_RS27715	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KIM5_RS27720	COG2814	Major facilitator Superfamily
KIM5_RS27730	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KIM5_RS27745	COG1454	alcohol dehydrogenase
KIM5_RS27750	COG3485	protocatechuate 3,4-dioxygenase
KIM5_RS27760	COG4948	Mandelate Racemase Muconate Lactonizing
KIM5_RS27765	COG3842	ATPase activity
KIM5_RS27780	COG1653	transport
KIM5_RS27795	COG4948	Mandelate Racemase Muconate Lactonizing
KIM5_RS27800	COG4948	Mandelate Racemase Muconate Lactonizing
KIM5_RS27805	COG3547	Transposase (IS116 IS110 IS902 family)
KIM5_RS27815	COG4372	Transposase
KIM5_RS27850	COG0740	serine-type endopeptidase activity
KIM5_RS27860	COG0640	Transcriptional regulator
KIM5_RS27865	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
KIM5_RS27880	COG0179	Fumarylacetoacetate (FAA) hydrolase
KIM5_RS27890	COG1063	alcohol dehydrogenase
KIM5_RS27930	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KIM5_RS27935	COG0754	glutathionylspermidine amidase activity
KIM5_RS27945	COG3766	membrane
KIM5_RS27960	COG3789	protein conserved in bacteria
KIM5_RS27970	COG3443	Belongs to the bacterial solute-binding protein 9 family
KIM5_RS27985	COG0765	amino acid transport
KIM5_RS27990	COG0765	amino acid transport
KIM5_RS27995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KIM5_RS28000	COG2186	Transcriptional regulator
KIM5_RS28010	COG0765	amino acid transport
KIM5_RS28015	COG0765	amino acid transport
KIM5_RS28025	COG1309	transcriptional regulator
KIM5_RS28030	COG0840	transmembrane signaling receptor activity
KIM5_RS28035	COG3608	succinylglutamate desuccinylase aspartoacylase
KIM5_RS28040	COG0006	proline dipeptidase activity
KIM5_RS28045	COG2423	ornithine cyclodeaminase activity
KIM5_RS28050	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KIM5_RS28055	COG3473	Maleate cis-trans isomerase
KIM5_RS28060	COG0765	amino acid transport
KIM5_RS28065	COG0765	amino acid transport
KIM5_RS28075	COG1126	abc transporter atp-binding protein
KIM5_RS28080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KIM5_RS28085	COG1522	sequence-specific DNA binding
KIM5_RS28090	COG1012	belongs to the aldehyde dehydrogenase family
KIM5_RS28095	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KIM5_RS28135	COG1653	transport
KIM5_RS28140	COG1609	Transcriptional regulator
KIM5_RS28145	COG1414	Transcriptional regulator
KIM5_RS28150	COG1475	DNA binding
KIM5_RS28155	COG1192	Involved in chromosome partitioning
KIM5_RS28175	COG4191	Histidine kinase
KIM5_RS28180	COG4566	intracellular signal transduction
KIM5_RS28185	COG0745	RESPONSE REGULATOR receiver
KIM5_RS28190	COG4566	intracellular signal transduction
KIM5_RS28195	COG0640	Transcriptional regulator
KIM5_RS28220	COG4172	Belongs to the ABC transporter superfamily
KIM5_RS28225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KIM5_RS28230	COG0601	transmembrane transport
KIM5_RS28235	COG0747	negative chemotaxis
KIM5_RS28240	COG2186	Transcriptional regulator
KIM5_RS28245	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KIM5_RS28250	COG3386	PFAM SMP-30 Gluconolaconase
KIM5_RS28255	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KIM5_RS28260	COG0747	negative chemotaxis
KIM5_RS28265	COG0601	transmembrane transport
KIM5_RS28270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KIM5_RS28275	COG0444	Belongs to the ABC transporter superfamily
KIM5_RS28280	COG4608	Belongs to the ABC transporter superfamily
KIM5_RS28285	COG0697	spore germination
KIM5_RS28295	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KIM5_RS28300	COG0392	lysyltransferase activity
KIM5_RS28355	COG1640	4-alpha-glucanotransferase
KIM5_RS28360	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KIM5_RS28405	COG1121	(ABC) transporter
KIM5_RS28410	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KIM5_RS28415	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KIM5_RS28430	COG1120	ATPase activity
KIM5_RS28440	COG1448	Aminotransferase
KIM5_RS28445	COG0028	Belongs to the TPP enzyme family
KIM5_RS28450	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KIM5_RS28455	COG0366	Alpha amylase catalytic
KIM5_RS28460	COG0366	Alpha amylase catalytic
KIM5_RS28470	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KIM5_RS28480	COG0598	Magnesium transport protein CorA
KIM5_RS28490	COG0840	transmembrane signaling receptor activity
KIM5_RS28495	COG1953	Uracil, thiamine, allantoin
KIM5_RS28505	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KIM5_RS28525	COG1609	Transcriptional regulator
KIM5_RS28540	COG0395	ABC-type sugar transport system, permease component
KIM5_RS28545	COG1175	transmembrane transport
KIM5_RS28560	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
KIM5_RS28580	COG0395	ABC-type sugar transport system, permease component
KIM5_RS28585	COG1175	transmembrane transport
KIM5_RS28615	COG2186	Transcriptional regulator
KIM5_RS28620	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KIM5_RS28630	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KIM5_RS28665	COG1175	transmembrane transport
KIM5_RS28670	COG0395	ABC-type sugar transport system, permease component
KIM5_RS28680	COG3842	ATPase activity
KIM5_RS28700	COG5002	protein histidine kinase activity
KIM5_RS28725	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KIM5_RS28730	COG0459	protein refolding
KIM5_RS28740	COG0277	FAD linked oxidase domain protein
KIM5_RS28740	COG0247	lactate metabolic process
KIM5_RS28770	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KIM5_RS28775	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KIM5_RS28785	COG1012	belongs to the aldehyde dehydrogenase family
KIM5_RS28790	COG0473	3-isopropylmalate dehydrogenase activity
KIM5_RS28800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KIM5_RS28810	COG0235	Class ii aldolase
KIM5_RS28815	COG1609	Transcriptional regulator
KIM5_RS28820	COG2084	Dehydrogenase
KIM5_RS28825	COG3622	Belongs to the hyi family
KIM5_RS28830	COG3395	kinase activity
KIM5_RS28850	COG0601	transmembrane transport
KIM5_RS28855	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KIM5_RS28860	COG4172	Belongs to the ABC transporter superfamily
KIM5_RS28870	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KIM5_RS28895	COG1522	sequence-specific DNA binding
KIM5_RS28905	COG0840	transmembrane signaling receptor activity
KIM5_RS28920	COG1522	sequence-specific DNA binding
KIM5_RS28935	COG0583	DNA-binding transcription factor activity
KIM5_RS28965	COG1012	belongs to the aldehyde dehydrogenase family
KIM5_RS28970	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KIM5_RS28975	COG1802	Transcriptional regulator
KIM5_RS28980	COG3791	Glutathione-dependent formaldehyde-activating
KIM5_RS28985	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
KIM5_RS28990	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KIM5_RS29005	COG2086	electron transfer activity
KIM5_RS29015	COG0446	pyridine nucleotide-disulphide oxidoreductase
KIM5_RS29015	COG1902	pentaerythritol trinitrate reductase activity
KIM5_RS29025	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KIM5_RS29035	COG4176	ABC-type proline glycine betaine transport system permease component
KIM5_RS29055	COG2207	Transcriptional regulator
KIM5_RS29055	COG3708	Transcriptional regulator
KIM5_RS29065	COG0243	molybdopterin cofactor binding
KIM5_RS29070	COG5001	Diguanylate cyclase
KIM5_RS29070	COG2203	Gaf domain
KIM5_RS29070	COG3706	GGDEF domain
KIM5_RS29070	COG4251	negative regulation of phosphorylation
KIM5_RS29215	COG0515	serine threonine protein kinase
KIM5_RS29245	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KIM5_RS29250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KIM5_RS29255	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KIM5_RS29325	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KIM5_RS29345	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KIM5_RS29355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KIM5_RS29360	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KIM5_RS29365	COG1522	sequence-specific DNA binding
KIM5_RS29420	COG3961	Belongs to the TPP enzyme family
KIM5_RS29425	COG3300	MHYT domain
KIM5_RS29425	COG5001	Diguanylate cyclase
KIM5_RS29430	COG0840	transmembrane signaling receptor activity
KIM5_RS29435	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KIM5_RS29440	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KIM5_RS29445	COG1116	anion transmembrane transporter activity
KIM5_RS29460	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KIM5_RS29480	COG0626	cystathionine gamma-synthase activity
KIM5_RS29510	COG4774	siderophore transport
KIM5_RS29535	COG2885	chlorophyll binding
KIM5_RS29540	COG0071	Belongs to the small heat shock protein (HSP20) family
KIM5_RS29560	COG0673	inositol 2-dehydrogenase activity
KIM5_RS29585	COG1609	Transcriptional regulator
KIM5_RS29595	COG0583	DNA-binding transcription factor activity
KIM5_RS29630	COG1522	sequence-specific DNA binding
KIM5_RS29640	COG0454	-acetyltransferase
KIM5_RS29650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KIM5_RS29660	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KIM5_RS29670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KIM5_RS29675	COG0601	transmembrane transport
KIM5_RS29690	COG2186	Transcriptional regulator
KIM5_RS29705	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KIM5_RS29735	COG1522	sequence-specific DNA binding
KIM5_RS29740	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KIM5_RS29760	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KIM5_RS29780	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KIM5_RS29815	COG0583	DNA-binding transcription factor activity
KIM5_RS29835	COG0631	protein serine/threonine phosphatase activity
KIM5_RS29850	COG0515	serine threonine protein kinase
KIM5_RS29850	COG2815	serine threonine protein kinase
KIM5_RS29990	COG1028	Short-chain dehydrogenase reductase Sdr
KIM5_RS29995	COG0277	FAD linked oxidase domain protein
KIM5_RS30005	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KIM5_RS30015	COG0492	ferredoxin-NADP+ reductase activity
KIM5_RS30055	COG0730	response to heat
KIM5_RS30080	COG0673	inositol 2-dehydrogenase activity
KIM5_RS30090	COG1175	transmembrane transport
KIM5_RS30095	COG0395	ABC-type sugar transport system, permease component
KIM5_RS30100	COG1940	carbohydrate kinase activity
KIM5_RS30115	COG1192	Involved in chromosome partitioning
KIM5_RS30120	COG1475	DNA binding
KIM5_RS30125	COG1414	Transcriptional regulator
KIM5_RS30140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KIM5_RS30145	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KIM5_RS30150	COG1473	amidohydrolase
KIM5_RS30160	COG1126	abc transporter atp-binding protein
KIM5_RS30165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KIM5_RS30210	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KIM5_RS30215	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
KIM5_RS30220	COG4521	taurine ABC transporter
KIM5_RS30235	COG0300	oxidoreductase activity
KIM5_RS30250	COG2267	carboxylic ester hydrolase activity
KIM5_RS30260	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KIM5_RS30265	COG1012	belongs to the aldehyde dehydrogenase family
KIM5_RS30285	COG1177	transmembrane transport
KIM5_RS30320	COG0395	ABC-type sugar transport system, permease component
KIM5_RS30325	COG1175	transmembrane transport
KIM5_RS30335	COG3250	beta-galactosidase activity
KIM5_RS30340	COG1609	Transcriptional regulator
KIM5_RS30345	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KIM5_RS30350	COG1802	Transcriptional regulator
KIM5_RS30360	COG1609	Transcriptional regulator
KIM5_RS30365	COG0747	negative chemotaxis
KIM5_RS30370	COG0601	transmembrane transport
KIM5_RS30375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KIM5_RS30380	COG0444	Belongs to the ABC transporter superfamily
KIM5_RS30385	COG4608	Belongs to the ABC transporter superfamily
KIM5_RS30390	COG3718	enzyme involved in inositol metabolism
KIM5_RS30405	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KIM5_RS30420	COG2030	dehydratase
KIM5_RS30430	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KIM5_RS30435	COG1960	acyl-CoA dehydrogenase activity
KIM5_RS30465	COG0183	Belongs to the thiolase family
KIM5_RS30470	COG1960	acyl-CoA dehydrogenase activity
KIM5_RS30480	COG0022	dehydrogenase e1 component
KIM5_RS30515	COG1864	DNA RNA non-specific endonuclease
KIM5_RS30515	COG3591	Belongs to the peptidase S1B family
KIM5_RS30525	COG0717	Belongs to the dCTP deaminase family
KIM5_RS30555	COG0753	catalase activity
KIM5_RS30560	COG1858	cytochrome C peroxidase
KIM5_RS30620	COG1172	Belongs to the binding-protein-dependent transport system permease family
KIM5_RS30625	COG1129	ABC transporter
KIM5_RS30665	COG1917	Cupin 2, conserved barrel domain protein
KIM5_RS30665	COG4977	sequence-specific DNA binding
KIM5_RS30670	COG0667	Aldo Keto reductase
KIM5_RS30680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KIM5_RS30685	COG0667	Aldo Keto reductase
KIM5_RS30715	COG3547	Transposase (IS116 IS110 IS902 family)
KIM5_RS30755	COG0840	transmembrane signaling receptor activity
KIM5_RS30770	COG2086	electron transfer activity
KIM5_RS30780	COG1028	Short-chain dehydrogenase reductase Sdr
KIM5_RS30785	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KIM5_RS30795	COG1028	Short-chain dehydrogenase reductase Sdr
KIM5_RS30865	COG4977	sequence-specific DNA binding
KIM5_RS30905	COG0523	cobalamin synthesis protein
KIM5_RS30920	COG0789	Transcriptional regulator
KIM5_RS30930	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KIM5_RS30945	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KIM5_RS30965	COG0071	Belongs to the small heat shock protein (HSP20) family
KIM5_RS30970	COG0071	Belongs to the small heat shock protein (HSP20) family
KIM5_RS31050	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
KIM5_RS31070	COG3609	addiction module antidote protein, CC2985 family
KIM5_RS31080	COG2972	Histidine kinase
KIM5_RS31080	COG0840	transmembrane signaling receptor activity
KIM5_RS31095	COG1172	Belongs to the binding-protein-dependent transport system permease family
KIM5_RS31105	COG0628	permease
KIM5_RS31155	COG1850	ribulose-bisphosphate carboxylase activity
KIM5_RS31165	COG1028	Short-chain dehydrogenase reductase Sdr
KIM5_RS31210	COG3838	Conjugal transfer protein Trbc
KIM5_RS31215	COG3702	type iv secretory pathway
KIM5_RS31220	COG3451	type IV secretory pathway VirB4
KIM5_RS31235	COG3704	protein secretion by the type IV secretion system
KIM5_RS31245	COG3736	Type IV secretory pathway, component VirB8
KIM5_RS31250	COG3504	Conjugal transfer protein
KIM5_RS31255	COG2948	multi-organism process
KIM5_RS31260	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
KIM5_RS31280	COG1475	DNA binding
KIM5_RS31340	COG3505	Type IV secretory pathway VirD4
KIM5_RS31365	COG0745	RESPONSE REGULATOR receiver
KIM5_RS31370	COG0156	8-amino-7-oxononanoate synthase activity
KIM5_RS31385	COG1176	ABC-type spermidine putrescine transport system, permease component I
KIM5_RS31390	COG3842	ATPase activity
KIM5_RS31400	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KIM5_RS31405	COG0028	Belongs to the TPP enzyme family
KIM5_RS31410	COG1028	Short-chain dehydrogenase reductase Sdr
KIM5_RS31415	COG0745	RESPONSE REGULATOR receiver
KIM5_RS31425	COG0330	HflC and HflK could
KIM5_RS31500	COG4964	Belongs to the GSP D family
KIM5_RS31520	COG4608	Belongs to the ABC transporter superfamily
KIM5_RS31525	COG0444	Belongs to the ABC transporter superfamily
KIM5_RS31530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KIM5_RS31535	COG0601	transmembrane transport
KIM5_RS31540	COG0747	negative chemotaxis
KIM5_RS31545	COG1414	Transcriptional regulator
KIM5_RS31560	COG4603	Belongs to the binding-protein-dependent transport system permease family
KIM5_RS31580	COG0625	glutathione transferase activity
KIM5_RS31625	COG1802	Transcriptional regulator
KIM5_RS31645	COG0488	(ABC) transporter
KIM5_RS31685	COG3842	ATPase activity
KIM5_RS31690	COG3842	ATPase activity
KIM5_RS31700	COG0395	ABC-type sugar transport system, permease component
KIM5_RS31715	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KIM5_RS31725	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KIM5_RS31730	COG1454	alcohol dehydrogenase
KIM5_RS31740	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KIM5_RS31745	COG0747	negative chemotaxis
KIM5_RS31750	COG0601	transmembrane transport
KIM5_RS31755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KIM5_RS31760	COG0444	Belongs to the ABC transporter superfamily
KIM5_RS31765	COG4608	Belongs to the ABC transporter superfamily
KIM5_RS31790	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KIM5_RS31795	COG0531	amino acid
KIM5_RS31810	COG4221	oxidoreductase activity
KIM5_RS31840	COG0673	inositol 2-dehydrogenase activity
KIM5_RS31845	COG1063	alcohol dehydrogenase
KIM5_RS31855	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KIM5_RS31890	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
KIM5_RS31895	COG0489	protein tyrosine kinase activity
KIM5_RS31895	COG3206	protein involved in exopolysaccharide biosynthesis
KIM5_RS31900	COG0297	glycogen (starch) synthase activity
KIM5_RS31910	COG1215	transferase activity, transferring glycosyl groups
KIM5_RS31950	COG2197	response regulator
KIM5_RS31960	COG0673	inositol 2-dehydrogenase activity
KIM5_RS31975	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KIM5_RS31980	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KIM5_RS32000	COG0523	cobalamin synthesis protein
KIM5_RS32010	COG0523	cobalamin synthesis protein
KIM5_RS32020	COG2274	protein secretion by the type I secretion system
KIM5_RS32035	COG2161	toxin-antitoxin pair type II binding
KIM5_RS32060	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KIM5_RS32065	COG0667	Aldo Keto reductase
KIM5_RS32075	COG1172	Belongs to the binding-protein-dependent transport system permease family
KIM5_RS32115	COG0584	glycerophosphoryl diester phosphodiesterase
KIM5_RS32120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KIM5_RS32130	COG4608	Belongs to the ABC transporter superfamily
KIM5_RS32140	COG0747	negative chemotaxis
KIM5_RS32150	COG0420	3'-5' exonuclease activity
KIM5_RS32155	COG4717	serine-type aminopeptidase activity
KIM5_RS32185	COG2267	carboxylic ester hydrolase activity
KIM5_RS32190	COG0601	transmembrane transport
KIM5_RS32195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KIM5_RS32210	COG0625	glutathione transferase activity
KIM5_RS32225	COG0395	ABC-type sugar transport system, permease component
KIM5_RS32230	COG1175	transmembrane transport
KIM5_RS32240	COG1802	Transcriptional regulator
KIM5_RS32245	COG5441	Belongs to the UPF0261 family
KIM5_RS32250	COG5564	TIM-barrel signal transduction protein
KIM5_RS32265	COG0484	heat shock protein binding
KIM5_RS32275	COG4589	Belongs to the CDS family
KIM5_RS32300	COG3845	ABC transporter
KIM5_RS32310	COG1079	Belongs to the binding-protein-dependent transport system permease family
KIM5_RS32315	COG0402	S-adenosylhomocysteine deaminase activity
KIM5_RS32325	COG2226	methyltransferase
KIM5_RS32335	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KIM5_RS32350	COG0395	ABC-type sugar transport system, permease component
KIM5_RS32355	COG1175	transmembrane transport
KIM5_RS32370	COG0673	inositol 2-dehydrogenase activity
KIM5_RS32375	COG1609	Transcriptional regulator
KIM5_RS32380	COG0747	negative chemotaxis
KIM5_RS32390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KIM5_RS32405	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KIM5_RS32420	COG1609	Transcriptional regulator
KIM5_RS32425	COG0584	glycerophosphoryl diester phosphodiesterase
KIM5_RS32430	COG3842	ATPase activity
KIM5_RS32440	COG1175	transmembrane transport
KIM5_RS32450	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KIM5_RS32460	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KIM5_RS32475	COG4988	ABC transporter
KIM5_RS32480	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KIM5_RS32485	COG1271	oxidase subunit
KIM5_RS32490	COG1294	oxidase, subunit
KIM5_RS32500	COG0667	Aldo Keto reductase
KIM5_RS32510	COG0395	ABC-type sugar transport system, permease component
KIM5_RS32540	COG0673	inositol 2-dehydrogenase activity
KIM5_RS32545	COG0673	inositol 2-dehydrogenase activity
KIM5_RS32560	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KIM5_RS32560	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KIM5_RS32565	COG2011	ABC-type metal ion transport system permease component
KIM5_RS32575	COG1464	Belongs to the NlpA lipoprotein family
KIM5_RS32580	COG2223	nitrite transmembrane transporter activity
KIM5_RS32585	COG1396	sequence-specific DNA binding
KIM5_RS32590	COG1192	Involved in chromosome partitioning
KIM5_RS32595	COG1475	DNA binding
KIM5_RS32600	COG1414	Transcriptional regulator
KIM5_RS32610	COG1609	Transcriptional regulator
KIM5_RS32615	COG1653	transport
KIM5_RS32620	COG1175	transmembrane transport
KIM5_RS32640	COG1621	beta-fructofuranosidase activity
KIM5_RS32655	COG1116	anion transmembrane transporter activity
KIM5_RS32660	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KIM5_RS32670	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KIM5_RS32680	COG4585	Histidine kinase
KIM5_RS32685	COG1879	ABC-type sugar transport system periplasmic component
KIM5_RS32690	COG1129	ABC transporter
KIM5_RS32695	COG1172	Belongs to the binding-protein-dependent transport system permease family
KIM5_RS32715	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KIM5_RS32725	COG1609	Transcriptional regulator
KIM5_RS32730	COG0395	ABC-type sugar transport system, permease component
KIM5_RS32735	COG1175	transmembrane transport
KIM5_RS32745	COG3842	ATPase activity
KIM5_RS32760	COG3300	MHYT domain
KIM5_RS32760	COG5001	Diguanylate cyclase
KIM5_RS32765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KIM5_RS32785	COG0583	DNA-binding transcription factor activity
KIM5_RS32795	COG3246	L-lysine catabolic process to acetate
KIM5_RS32800	COG1250	3-hydroxyacyl-CoA dehydrogenase
KIM5_RS32800	COG0824	Thioesterase
KIM5_RS32805	COG1960	acyl-CoA dehydrogenase activity
KIM5_RS32815	COG1024	Enoyl-CoA hydratase
KIM5_RS32820	COG0747	negative chemotaxis
KIM5_RS32825	COG0601	transmembrane transport
KIM5_RS32830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KIM5_RS32845	COG0747	negative chemotaxis
KIM5_RS32855	COG0657	acetylesterase activity
KIM5_RS32865	COG2304	oxidoreductase activity
KIM5_RS32885	COG1609	Transcriptional regulator
KIM5_RS32890	COG1063	alcohol dehydrogenase
KIM5_RS32895	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KIM5_RS32900	COG1028	Short-chain dehydrogenase reductase Sdr
KIM5_RS32905	COG3265	gluconokinase activity
KIM5_RS32910	COG2084	Dehydrogenase
KIM5_RS32915	COG1129	ABC transporter
KIM5_RS32920	COG1172	Belongs to the binding-protein-dependent transport system permease family
KIM5_RS32935	COG0840	transmembrane signaling receptor activity
KIM5_RS32960	COG1522	sequence-specific DNA binding
KIM5_RS32995	COG4139	cobalamin transport
KIM5_RS33000	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
KIM5_RS33025	COG1116	anion transmembrane transporter activity
KIM5_RS33040	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KIM5_RS33050	COG1879	ABC-type sugar transport system periplasmic component
KIM5_RS33055	COG1129	ABC transporter
KIM5_RS33065	COG1172	Belongs to the binding-protein-dependent transport system permease family
KIM5_RS33080	COG0251	oxidation-reduction process
KIM5_RS33095	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KIM5_RS33100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KIM5_RS33105	COG1126	abc transporter atp-binding protein
KIM5_RS33110	COG0765	amino acid transport
KIM5_RS33115	COG0765	amino acid transport
KIM5_RS33120	COG4221	oxidoreductase activity
KIM5_RS33130	COG0436	Aminotransferase
KIM5_RS33135	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
KIM5_RS33140	COG1984	allophanate hydrolase subunit 2
KIM5_RS33155	COG0439	Biotin carboxylase
KIM5_RS33160	COG0511	ligase activity, forming carbon-carbon bonds
KIM5_RS33170	COG1609	Transcriptional regulator
KIM5_RS33185	COG1175	transmembrane transport
KIM5_RS33190	COG0395	ABC-type sugar transport system, permease component
KIM5_RS33195	COG3842	ATPase activity
KIM5_RS33210	COG0667	Aldo Keto reductase
KIM5_RS33215	COG0583	DNA-binding transcription factor activity
KIM5_RS33235	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KIM5_RS33260	COG0745	RESPONSE REGULATOR receiver
KIM5_RS33265	COG2205	protein histidine kinase activity
KIM5_RS33270	COG1309	transcriptional regulator
KIM5_RS33275	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
KIM5_RS33280	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KIM5_RS33285	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KIM5_RS33290	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KIM5_RS33300	COG1609	Transcriptional regulator
KIM5_RS33305	COG1063	alcohol dehydrogenase
KIM5_RS33310	COG1028	Short-chain dehydrogenase reductase Sdr
KIM5_RS33320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KIM5_RS33325	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
KIM5_RS33330	COG1028	Short-chain dehydrogenase reductase Sdr
KIM5_RS33340	COG4214	carbohydrate transport
KIM5_RS33360	COG1877	trehalose-phosphatase activity
KIM5_RS33375	COG1192	Involved in chromosome partitioning
KIM5_RS33380	COG1475	DNA binding
KIM5_RS33385	COG1414	Transcriptional regulator