locus-tag	class	description
AMK01_RS00010	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AMK01_RS00015	COG0424	maF-like protein
AMK01_RS00020	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AMK01_RS00025	COG0237	dephospho-CoA kinase activity
AMK01_RS00030	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AMK01_RS00035	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AMK01_RS00050	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AMK01_RS00080	COG0435	Glutathione S-transferase
AMK01_RS00085	COG0179	Fumarylacetoacetate (FAA) hydrolase
AMK01_RS00105	COG0135	phosphoribosylanthranilate isomerase activity
AMK01_RS00110	COG0133	tryptophan synthase activity
AMK01_RS00115	COG0159	tryptophan synthase activity
AMK01_RS00120	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AMK01_RS00125	COG0285	dihydrofolate synthase activity
AMK01_RS00140	COG2887	Belongs to the helicase family. UvrD subfamily
AMK01_RS00145	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AMK01_RS00150	COG3178	'Phosphotransferase
AMK01_RS00155	COG2205	protein histidine kinase activity
AMK01_RS00160	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AMK01_RS00165	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMK01_RS00170	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMK01_RS00170	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AMK01_RS00180	COG0642	Histidine kinase
AMK01_RS00185	COG0745	RESPONSE REGULATOR receiver
AMK01_RS00190	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AMK01_RS00205	COG1072	(Pantothenic acid kinase))
AMK01_RS00210	COG0140	phosphoribosyl-ATP diphosphatase activity
AMK01_RS00215	COG0107	imidazoleglycerol-phosphate synthase activity
AMK01_RS00220	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AMK01_RS00235	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AMK01_RS00245	COG0131	Imidazoleglycerol-phosphate dehydratase
AMK01_RS00250	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AMK01_RS00255	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AMK01_RS00265	COG2124	cytochrome p450
AMK01_RS00270	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AMK01_RS00285	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AMK01_RS00295	COG1643	Atp-dependent helicase
AMK01_RS00300	COG2423	ornithine cyclodeaminase activity
AMK01_RS00345	COG2197	response regulator
AMK01_RS00360	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AMK01_RS00365	COG1215	transferase activity, transferring glycosyl groups
AMK01_RS00380	COG2182	Extracellular solute-binding protein
AMK01_RS00400	COG0673	inositol 2-dehydrogenase activity
AMK01_RS00415	COG0673	inositol 2-dehydrogenase activity
AMK01_RS00420	COG1309	transcriptional regulator
AMK01_RS00430	COG1175	transmembrane transport
AMK01_RS00435	COG0395	ABC-type sugar transport system, permease component
AMK01_RS00445	COG3842	ATPase activity
AMK01_RS00460	COG0246	Mannitol dehydrogenase
AMK01_RS00465	COG1904	glucuronate isomerase
AMK01_RS00470	COG2900	Belongs to the SlyX family
AMK01_RS00475	COG1012	belongs to the aldehyde dehydrogenase family
AMK01_RS00480	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AMK01_RS00500	COG0539	negative regulation of cytoplasmic translation
AMK01_RS00505	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AMK01_RS00635	COG0582	viral genome integration into host DNA
AMK01_RS00675	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AMK01_RS00685	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AMK01_RS00700	COG2813	Specifically methylates the guanine in position
AMK01_RS00705	COG1185	polyribonucleotide nucleotidyltransferase activity
AMK01_RS00710	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AMK01_RS00715	COG2267	carboxylic ester hydrolase activity
AMK01_RS00720	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AMK01_RS00725	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AMK01_RS00730	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AMK01_RS00745	COG0779	Required for maturation of 30S ribosomal subunits
AMK01_RS00750	COG2814	Major facilitator Superfamily
AMK01_RS00765	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AMK01_RS00770	COG2258	MOSC domain
AMK01_RS00775	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AMK01_RS00780	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AMK01_RS00795	COG2816	NAD+ diphosphatase activity
AMK01_RS00800	COG2378	regulation of single-species biofilm formation
AMK01_RS00815	COG1605	Chorismate mutase
AMK01_RS00815	COG0077	Prephenate dehydratase
AMK01_RS00820	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AMK01_RS00825	COG3474	cytochrome
AMK01_RS00830	COG0679	Auxin Efflux Carrier
AMK01_RS00835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AMK01_RS00860	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AMK01_RS00865	COG1396	sequence-specific DNA binding
AMK01_RS00875	COG0484	heat shock protein binding
AMK01_RS00880	COG0443	Heat shock 70 kDa protein
AMK01_RS00885	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AMK01_RS00895	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AMK01_RS00900	COG5001	Diguanylate cyclase
AMK01_RS00900	COG3300	MHYT domain
AMK01_RS00910	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AMK01_RS00910	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AMK01_RS00915	COG1674	ftsk spoiiie
AMK01_RS00920	COG0456	acetyltransferase
AMK01_RS00920	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AMK01_RS00925	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AMK01_RS00930	COG3454	Phosphonate metabolism
AMK01_RS00935	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AMK01_RS00940	COG3639	organic phosphonate transmembrane transporter activity
AMK01_RS00945	COG3639	organic phosphonate transmembrane transporter activity
AMK01_RS00955	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AMK01_RS00965	COG4778	phosphonate C-P lyase system protein PhnL
AMK01_RS00970	COG4107	phosphonate C-P lyase system protein PhnK
AMK01_RS00975	COG3627	carbon phosphorus lyase activity
AMK01_RS00980	COG3626	phosphonate metabolism
AMK01_RS00985	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
AMK01_RS00990	COG3624	Phosphonate C-P lyase system protein PhnG
AMK01_RS00995	COG2188	Transcriptional regulator
AMK01_RS01000	COG0588	phosphoglycerate mutase activity
AMK01_RS01005	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AMK01_RS01010	COG1132	(ABC) transporter
AMK01_RS01015	COG0837	glucose binding
AMK01_RS01020	COG1803	Methylglyoxal synthase
AMK01_RS01025	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
AMK01_RS01030	COG4166	transmembrane transport
AMK01_RS01035	COG4174	ABC transporter (Permease)
AMK01_RS01040	COG4239	(ABC) transporter, permease
AMK01_RS01045	COG4172	Belongs to the ABC transporter superfamily
AMK01_RS01060	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AMK01_RS01090	COG1744	ABC transporter substrate-binding protein PnrA-like
AMK01_RS01095	COG3845	ABC transporter
AMK01_RS01100	COG1079	Belongs to the binding-protein-dependent transport system permease family
AMK01_RS01105	COG1079	Belongs to the binding-protein-dependent transport system permease family
AMK01_RS01115	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AMK01_RS01120	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AMK01_RS01125	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AMK01_RS01130	COG3577	Aspartyl protease
AMK01_RS01135	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AMK01_RS01140	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AMK01_RS01145	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AMK01_RS01180	COG4964	Belongs to the GSP D family
AMK01_RS01210	COG1280	lysine exporter protein (LysE YggA)
AMK01_RS01220	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AMK01_RS01235	COG0154	amidase activity
AMK01_RS01240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AMK01_RS01250	COG0747	negative chemotaxis
AMK01_RS01265	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AMK01_RS01275	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AMK01_RS01285	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AMK01_RS01300	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AMK01_RS01310	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
AMK01_RS01325	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AMK01_RS01335	COG2089	acid synthase
AMK01_RS01340	COG0028	Belongs to the TPP enzyme family
AMK01_RS01345	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AMK01_RS01365	COG0318	PFAM AMP-dependent synthetase and ligase
AMK01_RS01415	COG0481	GTPase activity
AMK01_RS01425	COG1396	sequence-specific DNA binding
AMK01_RS01445	COG2137	regulation of response to DNA damage stimulus
AMK01_RS01475	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AMK01_RS01475	COG0596	Alpha beta hydrolase
AMK01_RS01480	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AMK01_RS01485	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AMK01_RS01490	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AMK01_RS01495	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AMK01_RS01500	COG0072	phenylalanine-tRNA ligase activity
AMK01_RS01500	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMK01_RS01510	COG0667	Aldo Keto reductase
AMK01_RS01520	COG3685	Protein conserved in bacteria
AMK01_RS01530	COG0456	acetyltransferase
AMK01_RS01565	COG1570	exodeoxyribonuclease VII activity
AMK01_RS01570	COG2249	NAD(P)H dehydrogenase (quinone) activity
AMK01_RS01575	COG1846	Transcriptional regulator
AMK01_RS01580	COG0697	spore germination
AMK01_RS01585	COG2309	aminopeptidase activity
AMK01_RS01590	COG0625	glutathione transferase activity
AMK01_RS01600	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AMK01_RS01605	COG1393	Belongs to the ArsC family
AMK01_RS01615	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AMK01_RS01620	COG4221	oxidoreductase activity
AMK01_RS01625	COG1028	Short-chain dehydrogenase reductase Sdr
AMK01_RS01635	COG0583	DNA-binding transcription factor activity
AMK01_RS01640	COG2207	Transcriptional regulator
AMK01_RS01645	COG1881	PFAM PEBP family protein
AMK01_RS01655	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AMK01_RS01670	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AMK01_RS01670	COG0519	Catalyzes the synthesis of GMP from XMP
AMK01_RS01715	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AMK01_RS01725	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AMK01_RS01735	COG1968	undecaprenyl-diphosphatase activity
AMK01_RS01755	COG0284	orotidine-5'-phosphate decarboxylase activity
AMK01_RS01765	COG3963	phosphatidate phosphatase activity
AMK01_RS01780	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AMK01_RS01785	COG0792	nuclease activity
AMK01_RS01795	COG0189	ligase activity
AMK01_RS01810	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AMK01_RS01820	COG0697	spore germination
AMK01_RS01825	COG1522	sequence-specific DNA binding
AMK01_RS01835	COG0756	dUTP diphosphatase activity
AMK01_RS01840	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AMK01_RS01870	COG2807	transmembrane transport
AMK01_RS01885	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AMK01_RS01895	COG0583	DNA-binding transcription factor activity
AMK01_RS01900	COG2814	Major facilitator Superfamily
AMK01_RS01910	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AMK01_RS01930	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AMK01_RS01940	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AMK01_RS01945	COG2226	methyltransferase
AMK01_RS01950	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AMK01_RS01955	COG1024	Enoyl-CoA hydratase
AMK01_RS01960	COG0268	Binds directly to 16S ribosomal RNA
AMK01_RS01965	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AMK01_RS01975	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AMK01_RS01980	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AMK01_RS01990	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AMK01_RS01995	COG1420	regulation of RNA biosynthetic process
AMK01_RS02000	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AMK01_RS02005	COG1957	nucleoside hydrolase
AMK01_RS02010	COG0071	Belongs to the small heat shock protein (HSP20) family
AMK01_RS02035	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AMK01_RS02040	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AMK01_RS02050	COG1396	sequence-specific DNA binding
AMK01_RS02055	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AMK01_RS02065	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AMK01_RS02070	COG1702	phosphate starvation-inducible protein PhoH
AMK01_RS02075	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AMK01_RS02100	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AMK01_RS02110	COG0180	Tryptophanyl-tRNA synthetase
AMK01_RS02140	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AMK01_RS02145	COG0281	malic enzyme
AMK01_RS02145	COG0280	phosphate acetyltransferase
AMK01_RS02155	COG5002	protein histidine kinase activity
AMK01_RS02155	COG0784	Response regulator, receiver
AMK01_RS02155	COG2205	protein histidine kinase activity
AMK01_RS02160	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AMK01_RS02170	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AMK01_RS02170	COG0116	Belongs to the methyltransferase superfamily
AMK01_RS02195	COG0776	regulation of translation
AMK01_RS02210	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AMK01_RS02215	COG1137	ATPase activity
AMK01_RS02225	COG0697	spore germination
AMK01_RS02230	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AMK01_RS02235	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMK01_RS02240	COG0840	transmembrane signaling receptor activity
AMK01_RS02245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AMK01_RS02255	COG0840	transmembrane signaling receptor activity
AMK01_RS02260	COG0242	peptide deformylase activity
AMK01_RS02275	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AMK01_RS02280	COG0101	tRNA pseudouridine synthase activity
AMK01_RS02290	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AMK01_RS02295	COG2171	N-acyltransferase activity
AMK01_RS02315	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AMK01_RS02315	COG2169	Transcriptional regulator
AMK01_RS02325	COG1304	FMN binding
AMK01_RS02340	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AMK01_RS02345	COG5484	DNA packaging
AMK01_RS02355	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AMK01_RS02360	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AMK01_RS02365	COG0706	membrane insertase activity
AMK01_RS02370	COG0594	ribonuclease P activity
AMK01_RS02375	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AMK01_RS02380	COG0840	transmembrane signaling receptor activity
AMK01_RS02430	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AMK01_RS02435	COG0667	Aldo Keto reductase
AMK01_RS02445	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AMK01_RS02450	COG3938	Belongs to the proline racemase family
AMK01_RS02470	COG1309	transcriptional regulator
AMK01_RS02490	COG5001	Diguanylate cyclase
AMK01_RS02490	COG3300	MHYT domain
AMK01_RS02495	COG0604	alcohol dehydrogenase
AMK01_RS02505	COG3546	catalase activity
AMK01_RS02535	COG1072	(Pantothenic acid kinase))
AMK01_RS02540	COG0418	dihydroorotase activity
AMK01_RS02555	COG1309	transcriptional regulator
AMK01_RS02560	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AMK01_RS02570	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AMK01_RS02575	COG0166	Belongs to the GPI family
AMK01_RS02580	COG0318	PFAM AMP-dependent synthetase and ligase
AMK01_RS02600	COG1174	glycine betaine transport
AMK01_RS02605	COG1125	glycine betaine transport
AMK01_RS02610	COG1174	glycine betaine transport
AMK01_RS02615	COG1732	Glycine betaine
AMK01_RS02620	COG0583	DNA-binding transcription factor activity
AMK01_RS02625	COG3142	Participates in the control of copper homeostasis
AMK01_RS02630	COG1063	alcohol dehydrogenase
AMK01_RS02635	COG1172	Belongs to the binding-protein-dependent transport system permease family
AMK01_RS02660	COG2721	sulfolactate sulfo-lyase activity
AMK01_RS02670	COG4178	(ABC) transporter
AMK01_RS02675	COG0477	Major facilitator Superfamily
AMK01_RS02705	COG2326	polyphosphate kinase activity
AMK01_RS02710	COG5002	protein histidine kinase activity
AMK01_RS02715	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AMK01_RS02720	COG0573	inorganic phosphate transmembrane transporter activity
AMK01_RS02730	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AMK01_RS02735	COG0704	Plays a role in the regulation of phosphate uptake
AMK01_RS02740	COG0745	RESPONSE REGULATOR receiver
AMK01_RS02750	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AMK01_RS02755	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AMK01_RS02760	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AMK01_RS02765	COG2967	ApaG domain
AMK01_RS02775	COG0717	Belongs to the dCTP deaminase family
AMK01_RS02800	COG4221	oxidoreductase activity
AMK01_RS02815	COG0840	transmembrane signaling receptor activity
AMK01_RS02825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMK01_RS02860	COG0167	dihydroorotate dehydrogenase activity
AMK01_RS02865	COG0534	Mate efflux family protein
AMK01_RS02890	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AMK01_RS02895	COG1959	2 iron, 2 sulfur cluster binding
AMK01_RS02905	COG1201	RNA secondary structure unwinding
AMK01_RS02940	COG0730	response to heat
AMK01_RS02955	COG1960	acyl-CoA dehydrogenase activity
AMK01_RS02960	COG0183	Belongs to the thiolase family
AMK01_RS02965	COG1250	3-hydroxyacyl-CoA dehydrogenase
AMK01_RS02965	COG1024	Enoyl-CoA hydratase
AMK01_RS02970	COG1278	Cold shock
AMK01_RS03000	COG2205	protein histidine kinase activity
AMK01_RS03000	COG0784	Response regulator, receiver
AMK01_RS03000	COG2198	Histidine kinase
AMK01_RS03005	COG1970	mechanosensitive ion channel activity
AMK01_RS03010	COG0436	Aminotransferase
AMK01_RS03020	COG5001	Diguanylate cyclase
AMK01_RS03030	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AMK01_RS03075	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AMK01_RS03085	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AMK01_RS03090	COG5328	Belongs to the UPF0262 family
AMK01_RS03095	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AMK01_RS03100	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AMK01_RS03105	COG0424	maF-like protein
AMK01_RS03110	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AMK01_RS03125	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AMK01_RS03160	COG3220	belongs to the UPF0276 family
AMK01_RS03185	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AMK01_RS03200	COG0251	oxidation-reduction process
AMK01_RS03205	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AMK01_RS03215	COG0444	Belongs to the ABC transporter superfamily
AMK01_RS03220	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AMK01_RS03240	COG2186	Transcriptional regulator
AMK01_RS03245	COG1609	Transcriptional regulator
AMK01_RS03260	COG1172	Belongs to the binding-protein-dependent transport system permease family
AMK01_RS03270	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AMK01_RS03280	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AMK01_RS03310	COG0346	lactoylglutathione lyase activity
AMK01_RS03315	COG4251	negative regulation of phosphorylation
AMK01_RS03325	COG4251	negative regulation of phosphorylation
AMK01_RS03335	COG2197	response regulator
AMK01_RS03360	COG4651	solute:proton antiporter activity
AMK01_RS03360	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AMK01_RS03370	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AMK01_RS03375	COG0840	transmembrane signaling receptor activity
AMK01_RS03385	COG0745	RESPONSE REGULATOR receiver
AMK01_RS03390	COG0643	Histidine kinase
AMK01_RS03390	COG2198	Histidine kinase
AMK01_RS03395	COG0835	chemotaxis
AMK01_RS03400	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AMK01_RS03405	COG2201	protein-glutamate methylesterase activity
AMK01_RS03410	COG0745	RESPONSE REGULATOR receiver
AMK01_RS03415	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AMK01_RS03425	COG1766	The M ring may be actively involved in energy transduction
AMK01_RS03430	COG2771	luxR family
AMK01_RS03445	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AMK01_RS03450	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AMK01_RS03455	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AMK01_RS03460	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AMK01_RS03465	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AMK01_RS03470	COG4786	Flagellar basal body rod
AMK01_RS03475	COG1157	protein secretion by the type III secretion system
AMK01_RS03485	COG1815	bacterial-type flagellum-dependent cell motility
AMK01_RS03490	COG1558	bacterial-type flagellum-dependent cell motility
AMK01_RS03495	COG1677	Flagellar hook-basal body complex protein FliE
AMK01_RS03500	COG4786	Flagellar basal body rod
AMK01_RS03505	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
AMK01_RS03510	COG1706	bacterial-type flagellum-dependent cell motility
AMK01_RS03520	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AMK01_RS03530	COG1338	Plays a role in the flagellum-specific transport system
AMK01_RS03540	COG1522	sequence-specific DNA binding
AMK01_RS03565	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AMK01_RS03600	COG1749	Flagellar hook protein flgE
AMK01_RS03605	COG1256	bacterial-type flagellum assembly
AMK01_RS03620	COG5443	negative regulation of bacterial-type flagellum assembly
AMK01_RS03630	COG4794	Type iii secretion
AMK01_RS03635	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AMK01_RS03640	COG1684	flagellar biosynthetic protein fliR
AMK01_RS03665	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AMK01_RS03675	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AMK01_RS03680	COG1609	Transcriptional regulator
AMK01_RS03685	COG1653	transport
AMK01_RS03690	COG1175	transmembrane transport
AMK01_RS03695	COG0395	ABC-type sugar transport system, permease component
AMK01_RS03700	COG0366	Alpha amylase catalytic
AMK01_RS03705	COG3842	ATPase activity
AMK01_RS03715	COG0129	dihydroxy-acid dehydratase activity
AMK01_RS03720	COG0363	glucosamine-6-phosphate deaminase activity
AMK01_RS03725	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AMK01_RS03730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AMK01_RS03735	COG0174	glutamine synthetase
AMK01_RS03740	COG2081	HI0933 family
AMK01_RS03745	COG2972	Histidine kinase
AMK01_RS03745	COG0840	transmembrane signaling receptor activity
AMK01_RS03750	COG0840	transmembrane signaling receptor activity
AMK01_RS03770	COG2224	Isocitrate lyase
AMK01_RS03780	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AMK01_RS03785	COG3842	ATPase activity
AMK01_RS03790	COG1176	ABC-type spermidine putrescine transport system, permease component I
AMK01_RS03795	COG1177	transmembrane transport
AMK01_RS03805	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AMK01_RS03810	COG2205	protein histidine kinase activity
AMK01_RS03825	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AMK01_RS03850	COG1959	2 iron, 2 sulfur cluster binding
AMK01_RS03855	COG0747	negative chemotaxis
AMK01_RS03860	COG0601	transmembrane transport
AMK01_RS03865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AMK01_RS03870	COG0444	Belongs to the ABC transporter superfamily
AMK01_RS03875	COG4608	Belongs to the ABC transporter superfamily
AMK01_RS03880	COG3265	gluconokinase activity
AMK01_RS03885	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AMK01_RS03890	COG1755	Isoprenylcysteine carboxyl methyltransferase
AMK01_RS03920	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AMK01_RS03945	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMK01_RS03950	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AMK01_RS03960	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AMK01_RS03965	COG2089	acid synthase
AMK01_RS03970	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
AMK01_RS03985	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AMK01_RS04015	COG1442	glycosyl transferase family 8
AMK01_RS04030	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMK01_RS04035	COG2813	Specifically methylates the guanine in position
AMK01_RS04050	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AMK01_RS04060	COG0477	Major facilitator Superfamily
AMK01_RS04090	COG0583	DNA-binding transcription factor activity
AMK01_RS04115	COG0306	phosphate transporter
AMK01_RS04125	COG0583	DNA-binding transcription factor activity
AMK01_RS04130	COG0277	FAD linked oxidase domain protein
AMK01_RS04135	COG0277	FAD linked oxidase domain protein
AMK01_RS04140	COG0247	lactate metabolic process
AMK01_RS04155	COG1376	ErfK ybiS ycfS ynhG family protein
AMK01_RS04155	COG1388	LysM domain
AMK01_RS04160	COG1376	ErfK ybiS ycfS ynhG family protein
AMK01_RS04165	COG2818	Glycosylase
AMK01_RS04180	COG0667	Aldo Keto reductase
AMK01_RS04200	COG0124	histidyl-tRNA synthetase
AMK01_RS04205	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AMK01_RS04210	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AMK01_RS04215	COG2259	Doxx family
AMK01_RS04220	COG0625	glutathione transferase activity
AMK01_RS04230	COG0459	protein refolding
AMK01_RS04235	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AMK01_RS04245	COG0196	riboflavin kinase activity
AMK01_RS04260	COG0590	tRNA wobble adenosine to inosine editing
AMK01_RS04265	COG1187	pseudouridine synthase activity
AMK01_RS04270	COG0742	ribosomal rna small subunit methyltransferase
AMK01_RS04275	COG1752	Esterase of the alpha-beta hydrolase superfamily
AMK01_RS04295	COG0312	modulator of DNA gyrase
AMK01_RS04300	COG0483	inositol monophosphate 1-phosphatase activity
AMK01_RS04310	COG1519	Transferase
AMK01_RS04320	COG1663	tetraacyldisaccharide 4'-kinase activity
AMK01_RS04330	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AMK01_RS04335	COG0745	RESPONSE REGULATOR receiver
AMK01_RS04340	COG5001	Diguanylate cyclase
AMK01_RS04340	COG3300	MHYT domain
AMK01_RS04350	COG3386	PFAM SMP-30 Gluconolaconase
AMK01_RS04355	COG0800	Aldolase
AMK01_RS04360	COG3734	2-keto-3-deoxy-galactonokinase
AMK01_RS04365	COG1028	Short-chain dehydrogenase reductase Sdr
AMK01_RS04370	COG1414	Transcriptional regulator
AMK01_RS04375	COG2197	response regulator
AMK01_RS04380	COG0489	protein tyrosine kinase activity
AMK01_RS04385	COG0598	Magnesium transport protein CorA
AMK01_RS04390	COG3158	transport of potassium into the cell
AMK01_RS04405	COG0356	it plays a direct role in the translocation of protons across the membrane
AMK01_RS04415	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AMK01_RS04420	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AMK01_RS04425	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AMK01_RS04445	COG0521	Mo-molybdopterin cofactor biosynthetic process
AMK01_RS04450	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AMK01_RS04460	COG0142	geranyltranstransferase activity
AMK01_RS04475	COG1914	H( )-stimulated, divalent metal cation uptake system
AMK01_RS04490	COG0752	glycyl-tRNA synthetase alpha subunit
AMK01_RS04495	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AMK01_RS04500	COG1704	LemA family
AMK01_RS04505	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AMK01_RS04515	COG0151	Belongs to the GarS family
AMK01_RS04530	COG1683	Conserved Protein
AMK01_RS04535	COG0751	glycine-tRNA ligase activity
AMK01_RS04540	COG2183	response to ionizing radiation
AMK01_RS04545	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AMK01_RS04550	COG0406	alpha-ribazole phosphatase activity
AMK01_RS04580	COG0009	L-threonylcarbamoyladenylate synthase
AMK01_RS04590	COG4638	Rieske (2fe-2S)
AMK01_RS04610	COG1960	acyl-CoA dehydrogenase activity
AMK01_RS04625	COG1028	Short-chain dehydrogenase reductase Sdr
AMK01_RS04630	COG1733	regulation of RNA biosynthetic process
AMK01_RS04635	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AMK01_RS04645	COG0840	transmembrane signaling receptor activity
AMK01_RS04650	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AMK01_RS04660	COG1741	Belongs to the pirin family
AMK01_RS04670	COG1722	exodeoxyribonuclease VII activity
AMK01_RS04675	COG0123	including yeast histone deacetylase and acetoin utilization protein
AMK01_RS04685	COG1802	Transcriptional regulator
AMK01_RS04695	COG0318	PFAM AMP-dependent synthetase and ligase
AMK01_RS04705	COG0662	Cupin 2, conserved barrel domain protein
AMK01_RS04710	COG0583	DNA-binding transcription factor activity
AMK01_RS04725	COG1268	BioY protein
AMK01_RS04730	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AMK01_RS04735	COG1122	ATPase activity
AMK01_RS04740	COG3214	Protein conserved in bacteria
AMK01_RS04745	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AMK01_RS04745	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AMK01_RS04750	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AMK01_RS04775	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AMK01_RS04780	COG0484	heat shock protein binding
AMK01_RS04790	COG0259	pyridoxamine-phosphate oxidase activity
AMK01_RS04800	COG1686	Belongs to the peptidase S11 family
AMK01_RS04810	COG0306	phosphate transporter
AMK01_RS04815	COG1392	Phosphate transport regulator
AMK01_RS04830	COG0312	modulator of DNA gyrase
AMK01_RS04845	COG1565	acr, cog1565
AMK01_RS04845	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AMK01_RS04850	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AMK01_RS04855	COG0109	protoheme IX farnesyltransferase activity
AMK01_RS04860	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AMK01_RS04870	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AMK01_RS04885	COG3346	SURF1 family
AMK01_RS04890	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AMK01_RS04895	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AMK01_RS04900	COG0328	RNA-DNA hybrid ribonuclease activity
AMK01_RS04920	COG1678	Uncharacterized ACR, COG1678
AMK01_RS04930	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AMK01_RS04930	COG0678	peroxiredoxin activity
AMK01_RS04940	COG1121	(ABC) transporter
AMK01_RS04945	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AMK01_RS04950	COG0803	Belongs to the bacterial solute-binding protein 9 family
AMK01_RS04970	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AMK01_RS04975	COG0612	Peptidase, M16
AMK01_RS04990	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AMK01_RS04995	COG2814	Major facilitator Superfamily
AMK01_RS05040	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AMK01_RS05055	COG1194	a g-specific adenine glycosylase
AMK01_RS05080	COG1196	nuclear chromosome segregation
AMK01_RS05085	COG0625	glutathione transferase activity
AMK01_RS05090	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AMK01_RS05090	COG0574	Belongs to the PEP-utilizing enzyme family
AMK01_RS05150	COG1715	Restriction endonuclease
AMK01_RS05170	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AMK01_RS05175	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
AMK01_RS05215	COG0318	PFAM AMP-dependent synthetase and ligase
AMK01_RS05215	COG0204	Acyl-transferase
AMK01_RS05225	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AMK01_RS05245	COG1733	regulation of RNA biosynthetic process
AMK01_RS05335	COG0640	Transcriptional regulator
AMK01_RS05340	COG1028	Short-chain dehydrogenase reductase Sdr
AMK01_RS05370	COG1028	Short-chain dehydrogenase reductase Sdr
AMK01_RS05375	COG2207	Transcriptional regulator
AMK01_RS05420	COG0659	secondary active sulfate transmembrane transporter activity
AMK01_RS05425	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AMK01_RS05465	COG0640	Transcriptional regulator
AMK01_RS05480	COG0640	Transcriptional regulator
AMK01_RS05645	COG0110	maltose O-acetyltransferase activity
AMK01_RS05715	COG4106	trans-aconitate 2-methyltransferase activity
AMK01_RS05740	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AMK01_RS05745	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AMK01_RS05760	COG1609	Transcriptional regulator
AMK01_RS05765	COG0583	DNA-binding transcription factor activity
AMK01_RS05810	COG0175	sulfate reduction
AMK01_RS05815	COG0175	sulfate reduction
AMK01_RS05820	COG1959	2 iron, 2 sulfur cluster binding
AMK01_RS05825	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AMK01_RS05830	COG1012	belongs to the aldehyde dehydrogenase family
AMK01_RS05835	COG1309	transcriptional regulator
AMK01_RS05850	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AMK01_RS05870	COG2814	Major facilitator Superfamily
AMK01_RS05885	COG1349	DNA-binding transcription factor activity
AMK01_RS05910	COG1129	ABC transporter
AMK01_RS05910	COG0842	Transport permease protein
AMK01_RS05940	COG0583	DNA-binding transcription factor activity
AMK01_RS05945	COG0435	Glutathione S-transferase
AMK01_RS05955	COG1881	PFAM PEBP family protein
AMK01_RS05970	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AMK01_RS05970	COG1672	PFAM Archaeal ATPase
AMK01_RS05985	COG0584	glycerophosphoryl diester phosphodiesterase
AMK01_RS05990	COG0596	Alpha beta hydrolase
AMK01_RS06000	COG1793	dna ligase
AMK01_RS06010	COG1376	ErfK ybiS ycfS ynhG family protein
AMK01_RS06015	COG1376	ErfK ybiS ycfS ynhG family protein
AMK01_RS06020	COG1278	Cold shock
AMK01_RS06030	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AMK01_RS06040	COG1846	Transcriptional regulator
AMK01_RS06045	COG1764	response to oxidative stress
AMK01_RS06070	COG0488	(ABC) transporter
AMK01_RS06075	COG0488	(ABC) transporter
AMK01_RS06085	COG0433	COG0433 Predicted ATPase
AMK01_RS06095	COG1051	belongs to the nudix hydrolase family
AMK01_RS06105	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AMK01_RS06110	COG4106	trans-aconitate 2-methyltransferase activity
AMK01_RS06115	COG1253	flavin adenine dinucleotide binding
AMK01_RS06130	COG1064	alcohol dehydrogenase
AMK01_RS06135	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AMK01_RS06140	COG0583	DNA-binding transcription factor activity
AMK01_RS06165	COG0625	glutathione transferase activity
AMK01_RS06175	COG2814	Major facilitator Superfamily
AMK01_RS06185	COG0730	response to heat
AMK01_RS06200	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AMK01_RS06215	COG1280	lysine exporter protein (LysE YggA)
AMK01_RS06235	COG0583	DNA-binding transcription factor activity
AMK01_RS06245	COG2010	Cytochrome c
AMK01_RS06285	COG4993	Dehydrogenase
AMK01_RS06290	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AMK01_RS06295	COG0477	Major facilitator Superfamily
AMK01_RS06335	COG2514	catechol 2,3-dioxygenase activity
AMK01_RS06345	COG1272	protein, Hemolysin III
AMK01_RS06360	COG5425	PFAM Usg family protein
AMK01_RS06365	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AMK01_RS06370	COG0459	protein refolding
AMK01_RS06380	COG0438	transferase activity, transferring glycosyl groups
AMK01_RS06395	COG0071	Belongs to the small heat shock protein (HSP20) family
AMK01_RS06400	COG0071	Belongs to the small heat shock protein (HSP20) family
AMK01_RS06410	COG0519	Catalyzes the synthesis of GMP from XMP
AMK01_RS06415	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AMK01_RS06425	COG4957	zinc ion binding
AMK01_RS06430	COG2166	iron-sulfur cluster assembly
AMK01_RS06440	COG2205	protein histidine kinase activity
AMK01_RS06450	COG0840	transmembrane signaling receptor activity
AMK01_RS06475	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AMK01_RS06480	COG2983	Belongs to the UPF0260 family
AMK01_RS06490	COG4221	oxidoreductase activity
AMK01_RS06510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AMK01_RS06525	COG0625	glutathione transferase activity
AMK01_RS06540	COG1309	transcriptional regulator
AMK01_RS06580	COG4235	cytochrome complex assembly
AMK01_RS06585	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AMK01_RS06590	COG1138	Cytochrome C-type biogenesis protein
AMK01_RS06595	COG3088	subunit of a heme lyase
AMK01_RS06605	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AMK01_RS06610	COG0745	RESPONSE REGULATOR receiver
AMK01_RS06615	COG2205	protein histidine kinase activity
AMK01_RS06620	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AMK01_RS06625	COG2205	protein histidine kinase activity
AMK01_RS06625	COG2202	Pas domain
AMK01_RS06630	COG0308	aminopeptidase N
AMK01_RS06655	COG0443	Heat shock 70 kDa protein
AMK01_RS06685	COG1376	ErfK ybiS ycfS ynhG family protein
AMK01_RS06700	COG2239	Acts as a magnesium transporter
AMK01_RS06705	COG2814	Major facilitator Superfamily
AMK01_RS06715	COG0174	glutamine synthetase
AMK01_RS06725	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AMK01_RS06730	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AMK01_RS06735	COG0463	Glycosyl transferase, family 2
AMK01_RS06740	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AMK01_RS06750	COG4941	Belongs to the sigma-70 factor family
AMK01_RS06760	COG3795	YCII-related domain
AMK01_RS06765	COG3795	YCII-related domain
AMK01_RS06775	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AMK01_RS06800	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AMK01_RS06845	COG3718	enzyme involved in inositol metabolism
AMK01_RS06850	COG1082	Xylose isomerase domain protein TIM barrel
AMK01_RS06860	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AMK01_RS06870	COG0673	inositol 2-dehydrogenase activity
AMK01_RS06890	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AMK01_RS06900	COG0297	glycogen (starch) synthase activity
AMK01_RS06910	COG1215	transferase activity, transferring glycosyl groups
AMK01_RS06945	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMK01_RS06960	COG2197	response regulator
AMK01_RS06970	COG0673	inositol 2-dehydrogenase activity
AMK01_RS06985	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMK01_RS06990	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AMK01_RS07010	COG0523	cobalamin synthesis protein
AMK01_RS07020	COG0523	cobalamin synthesis protein
AMK01_RS07050	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AMK01_RS07055	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AMK01_RS07065	COG1758	RNA polymerase activity
AMK01_RS07085	COG0736	holo-[acyl-carrier-protein] synthase activity
AMK01_RS07090	COG0681	Belongs to the peptidase S26 family
AMK01_RS07095	COG0571	ribonuclease III activity
AMK01_RS07100	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AMK01_RS07105	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AMK01_RS07115	COG1381	Involved in DNA repair and RecF pathway recombination
AMK01_RS07120	COG0656	L-ascorbic acid biosynthetic process
AMK01_RS07130	COG1418	mRNA catabolic process
AMK01_RS07135	COG5001	Diguanylate cyclase
AMK01_RS07135	COG3300	MHYT domain
AMK01_RS07145	COG2032	superoxide dismutase activity
AMK01_RS07150	COG0668	transmembrane transport
AMK01_RS07160	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AMK01_RS07165	COG0354	folic acid binding
AMK01_RS07185	COG1051	belongs to the nudix hydrolase family
AMK01_RS07190	COG1742	UPF0060 membrane protein
AMK01_RS07205	COG0688	phosphatidylethanolamine metabolic process
AMK01_RS07210	COG0640	Transcriptional regulator
AMK01_RS07220	COG0740	serine-type endopeptidase activity
AMK01_RS07225	COG5265	(ABC) transporter
AMK01_RS07245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AMK01_RS07265	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AMK01_RS07290	COG2852	Protein conserved in bacteria
AMK01_RS07295	COG0215	cysteine-tRNA ligase activity
AMK01_RS07305	COG4221	oxidoreductase activity
AMK01_RS07310	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AMK01_RS07315	COG1286	toxin biosynthetic process
AMK01_RS07325	COG1280	lysine exporter protein (LysE YggA)
AMK01_RS07330	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AMK01_RS07350	COG0305	Participates in initiation and elongation during chromosome replication
AMK01_RS07355	COG0359	binds to the 23S rRNA
AMK01_RS07365	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AMK01_RS07370	COG0360	Binds together with S18 to 16S ribosomal RNA
AMK01_RS07375	COG0667	Aldo Keto reductase
AMK01_RS07385	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AMK01_RS07395	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AMK01_RS07400	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AMK01_RS07405	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AMK01_RS07410	COG1561	YicC-like family, N-terminal region
AMK01_RS07415	COG0194	GDP metabolic process
AMK01_RS07420	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AMK01_RS07425	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AMK01_RS07435	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AMK01_RS07450	COG0671	phosphoesterase, PA-phosphatase related
AMK01_RS07455	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AMK01_RS07470	COG1505	serine-type exopeptidase activity
AMK01_RS07480	COG0488	(ABC) transporter
AMK01_RS07500	COG0105	UTP biosynthetic process
AMK01_RS07520	COG0314	molybdopterin synthase activity
AMK01_RS07530	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AMK01_RS07535	COG0322	excinuclease ABC activity
AMK01_RS07540	COG1028	Short-chain dehydrogenase reductase Sdr
AMK01_RS07555	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AMK01_RS07560	COG0243	molybdopterin cofactor binding
AMK01_RS07565	COG0494	nUDIX hydrolase
AMK01_RS07570	COG3454	Phosphonate metabolism
AMK01_RS07575	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AMK01_RS07580	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AMK01_RS07585	COG0628	permease
AMK01_RS07595	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AMK01_RS07610	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AMK01_RS07615	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AMK01_RS07620	COG2132	Multicopper oxidase
AMK01_RS07625	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AMK01_RS07635	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AMK01_RS07655	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AMK01_RS07665	COG0113	porphobilinogen synthase activity
AMK01_RS07685	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AMK01_RS07690	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AMK01_RS07695	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AMK01_RS07695	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AMK01_RS07705	COG0519	Catalyzes the synthesis of GMP from XMP
AMK01_RS07720	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AMK01_RS07725	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AMK01_RS07730	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AMK01_RS07750	COG0416	fatty acid biosynthetic process
AMK01_RS07755	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AMK01_RS07760	COG0776	regulation of translation
AMK01_RS07790	COG1215	transferase activity, transferring glycosyl groups
AMK01_RS07800	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AMK01_RS07810	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AMK01_RS07830	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AMK01_RS07850	COG1940	carbohydrate kinase activity
AMK01_RS07870	COG1175	transmembrane transport
AMK01_RS07875	COG0395	ABC-type sugar transport system, permease component
AMK01_RS07890	COG0297	glycogen (starch) synthase activity
AMK01_RS07915	COG1612	heme a metabolic process
AMK01_RS07925	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AMK01_RS07930	COG0010	Belongs to the arginase family
AMK01_RS07940	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AMK01_RS07945	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AMK01_RS07965	COG1832	CoA-binding protein
AMK01_RS08005	COG3300	MHYT domain
AMK01_RS08005	COG5001	Diguanylate cyclase
AMK01_RS08015	COG3706	GGDEF domain
AMK01_RS08020	COG0740	serine-type endopeptidase activity
AMK01_RS08025	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AMK01_RS08030	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AMK01_RS08035	COG0776	regulation of translation
AMK01_RS08040	COG0697	spore germination
AMK01_RS08045	COG0667	Aldo Keto reductase
AMK01_RS08065	COG0386	Belongs to the glutathione peroxidase family
AMK01_RS08090	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMK01_RS08095	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMK01_RS08100	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMK01_RS08105	COG0649	NAD binding
AMK01_RS08115	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AMK01_RS08120	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AMK01_RS08125	COG3743	rRNA binding
AMK01_RS08125	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AMK01_RS08135	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AMK01_RS08140	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMK01_RS08150	COG0713	ATP synthesis coupled electron transport
AMK01_RS08165	COG1007	ATP synthesis coupled electron transport
AMK01_RS08170	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AMK01_RS08170	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AMK01_RS08180	COG0346	lactoylglutathione lyase activity
AMK01_RS08190	COG0442	prolyl-tRNA aminoacylation
AMK01_RS08200	COG1136	(ABC) transporter
AMK01_RS08220	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AMK01_RS08240	COG0784	Response regulator, receiver
AMK01_RS08250	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AMK01_RS08255	COG0477	Major facilitator Superfamily
AMK01_RS08265	COG0557	exoribonuclease II activity
AMK01_RS08270	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AMK01_RS08275	COG0758	DNA mediated transformation
AMK01_RS08280	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AMK01_RS08290	COG0540	Belongs to the ATCase OTCase family
AMK01_RS08295	COG1960	acyl-CoA dehydrogenase activity
AMK01_RS08300	COG1530	ribonuclease E activity
AMK01_RS08305	COG0860	N-Acetylmuramoyl-L-alanine amidase
AMK01_RS08310	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AMK01_RS08330	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AMK01_RS08350	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AMK01_RS08365	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AMK01_RS08370	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMK01_RS08380	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AMK01_RS08390	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AMK01_RS08395	COG0081	regulation of translation
AMK01_RS08400	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AMK01_RS08405	COG0222	ribosome binding
AMK01_RS08410	COG0085	RNA polymerase activity
AMK01_RS08415	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AMK01_RS08425	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AMK01_RS08430	COG0049	tRNA binding
AMK01_RS08435	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AMK01_RS08440	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AMK01_RS08445	COG0051	transcription antitermination factor activity, RNA binding
AMK01_RS08450	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AMK01_RS08455	COG0088	Forms part of the polypeptide exit tunnel
AMK01_RS08460	COG0089	rRNA binding
AMK01_RS08465	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AMK01_RS08470	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AMK01_RS08475	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AMK01_RS08480	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AMK01_RS08485	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AMK01_RS08490	COG0255	Belongs to the universal ribosomal protein uL29 family
AMK01_RS08495	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AMK01_RS08500	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AMK01_RS08505	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AMK01_RS08510	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AMK01_RS08515	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AMK01_RS08520	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AMK01_RS08525	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AMK01_RS08530	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AMK01_RS08535	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AMK01_RS08540	COG1841	ribosomal large subunit assembly
AMK01_RS08545	COG0200	Binds to the 23S rRNA
AMK01_RS08555	COG0563	adenylate kinase activity
AMK01_RS08560	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AMK01_RS08565	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AMK01_RS08570	COG0202	RNA polymerase activity
AMK01_RS08575	COG0203	ribosomal protein L17
AMK01_RS08590	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AMK01_RS08595	COG0129	dihydroxy-acid dehydratase activity
AMK01_RS08610	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AMK01_RS08615	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AMK01_RS08625	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AMK01_RS08630	COG1028	Short-chain dehydrogenase reductase Sdr
AMK01_RS08635	COG0583	DNA-binding transcription factor activity
AMK01_RS08655	COG5002	protein histidine kinase activity
AMK01_RS08660	COG1609	Transcriptional regulator
AMK01_RS08670	COG1024	Enoyl-CoA hydratase
AMK01_RS08675	COG1012	belongs to the aldehyde dehydrogenase family
AMK01_RS08680	COG1653	transport
AMK01_RS08685	COG1175	transmembrane transport
AMK01_RS08690	COG0395	ABC-type sugar transport system, permease component
AMK01_RS08695	COG3842	ATPase activity
AMK01_RS08710	COG0673	inositol 2-dehydrogenase activity
AMK01_RS08715	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AMK01_RS08745	COG2197	response regulator
AMK01_RS08795	COG1522	sequence-specific DNA binding
AMK01_RS08800	COG1522	sequence-specific DNA binding
AMK01_RS08810	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AMK01_RS08820	COG0625	glutathione transferase activity
AMK01_RS08860	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AMK01_RS08865	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AMK01_RS08875	COG1058	Belongs to the CinA family
AMK01_RS08875	COG1546	Belongs to the CinA family
AMK01_RS08890	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AMK01_RS08900	COG3706	GGDEF domain
AMK01_RS08905	COG1028	Short-chain dehydrogenase reductase Sdr
AMK01_RS08915	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AMK01_RS08920	COG0583	DNA-binding transcription factor activity
AMK01_RS08925	COG0737	Belongs to the 5'-nucleotidase family
AMK01_RS08940	COG1522	sequence-specific DNA binding
AMK01_RS08945	COG0686	Belongs to the AlaDH PNT family
AMK01_RS08960	COG2897	thiosulfate sulfurtransferase activity
AMK01_RS08970	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AMK01_RS08975	COG3806	Anti-sigma factor
AMK01_RS08980	COG0300	oxidoreductase activity
AMK01_RS08990	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AMK01_RS08995	COG0243	molybdopterin cofactor binding
AMK01_RS09005	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AMK01_RS09015	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AMK01_RS09020	COG3707	response regulator
AMK01_RS09025	COG0450	alkyl hydroperoxide reductase
AMK01_RS09080	COG3237	CsbD-like
AMK01_RS09130	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AMK01_RS09140	COG0525	valine-tRNA ligase activity
AMK01_RS09165	COG0316	Belongs to the HesB IscA family
AMK01_RS09170	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AMK01_RS09175	COG0018	arginyl-trna synthetase
AMK01_RS09185	COG1472	Belongs to the glycosyl hydrolase 3 family
AMK01_RS09190	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AMK01_RS09195	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AMK01_RS09200	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AMK01_RS09205	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AMK01_RS09210	COG0805	protein transport
AMK01_RS09215	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AMK01_RS09220	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AMK01_RS09225	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AMK01_RS09245	COG0739	heme binding
AMK01_RS09255	COG1862	Preprotein translocase
AMK01_RS09280	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AMK01_RS09310	COG0544	peptidyl-prolyl cis-trans isomerase activity
AMK01_RS09320	COG1032	radical SAM domain protein
AMK01_RS09345	COG2003	Belongs to the UPF0758 family
AMK01_RS09350	COG0024	Methionine aminopeptidase
AMK01_RS09365	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AMK01_RS09370	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AMK01_RS09375	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AMK01_RS09380	COG0154	amidase activity
AMK01_RS09425	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AMK01_RS09445	COG4765	Protein conserved in bacteria
AMK01_RS09455	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AMK01_RS09465	COG0511	ligase activity, forming carbon-carbon bonds
AMK01_RS09470	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AMK01_RS09480	COG0436	Aminotransferase
AMK01_RS09490	COG3243	poly(R)-hydroxyalkanoic acid synthase
AMK01_RS09500	COG0436	Aminotransferase
AMK01_RS09515	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AMK01_RS09545	COG1278	Cold shock
AMK01_RS09585	COG1126	abc transporter atp-binding protein
AMK01_RS09590	COG0765	amino acid transport
AMK01_RS09595	COG4597	amino acid ABC transporter
AMK01_RS09600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMK01_RS09605	COG0626	cystathionine gamma-synthase activity
AMK01_RS09620	COG2267	carboxylic ester hydrolase activity
AMK01_RS09640	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AMK01_RS09650	COG0537	adenosine 5'-monophosphoramidase activity
AMK01_RS09695	COG0052	Belongs to the universal ribosomal protein uS2 family
AMK01_RS09700	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AMK01_RS09705	COG0528	UMP kinase activity
AMK01_RS09710	COG0233	cytoplasmic translational termination
AMK01_RS09715	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AMK01_RS09725	COG0750	zinc metalloprotease
AMK01_RS09735	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AMK01_RS09740	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AMK01_RS09745	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AMK01_RS09750	COG3494	Protein of unknown function (DUF1009)
AMK01_RS09755	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AMK01_RS09770	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AMK01_RS09780	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AMK01_RS09785	COG0148	phosphopyruvate hydratase activity
AMK01_RS09795	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AMK01_RS09800	COG0022	dehydrogenase e1 component
AMK01_RS09800	COG0508	dehydrogenase complex catalyzes the overall conversion of
AMK01_RS09805	COG0508	dehydrogenase complex catalyzes the overall conversion of
AMK01_RS09820	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AMK01_RS09835	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AMK01_RS09845	COG2867	negative regulation of translational initiation
AMK01_RS09855	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AMK01_RS09855	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AMK01_RS09870	COG2204	response regulator
AMK01_RS09895	COG0583	DNA-binding transcription factor activity
AMK01_RS09900	COG2814	Major facilitator Superfamily
AMK01_RS09905	COG0583	DNA-binding transcription factor activity
AMK01_RS09910	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AMK01_RS09915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMK01_RS09920	COG4597	amino acid ABC transporter
AMK01_RS09925	COG0765	amino acid transport
AMK01_RS09930	COG1126	abc transporter atp-binding protein
AMK01_RS09935	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AMK01_RS09940	COG0667	Aldo Keto reductase
AMK01_RS09970	COG0436	Aminotransferase
AMK01_RS09990	COG1028	Short-chain dehydrogenase reductase Sdr
AMK01_RS09995	COG3836	Belongs to the HpcH HpaI aldolase family
AMK01_RS10000	COG5000	phosphorelay sensor kinase activity
AMK01_RS10005	COG2204	response regulator
AMK01_RS10010	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AMK01_RS10015	COG1923	regulation of RNA biosynthetic process
AMK01_RS10020	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AMK01_RS10025	COG3956	TIGRFAM MazG family protein
AMK01_RS10035	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AMK01_RS10035	COG1648	precorrin-2 dehydrogenase activity
AMK01_RS10055	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AMK01_RS10060	COG0679	Auxin Efflux Carrier
AMK01_RS10065	COG0785	Cytochrome C biogenesis protein
AMK01_RS10160	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AMK01_RS10225	COG4245	von Willebrand factor, type A
AMK01_RS10270	COG3436	PFAM IS66 Orf2 family protein
AMK01_RS10275	COG4372	Transposase
AMK01_RS10355	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AMK01_RS10380	COG5265	(ABC) transporter
AMK01_RS10415	COG1028	Short-chain dehydrogenase reductase Sdr
AMK01_RS10425	COG2207	Transcriptional regulator
AMK01_RS10440	COG2249	NAD(P)H dehydrogenase (quinone) activity
AMK01_RS10450	COG0402	S-adenosylhomocysteine deaminase activity
AMK01_RS10460	COG1116	anion transmembrane transporter activity
AMK01_RS10500	COG1653	transport
AMK01_RS10505	COG1175	transmembrane transport
AMK01_RS10510	COG0395	ABC-type sugar transport system, permease component
AMK01_RS10515	COG3842	ATPase activity
AMK01_RS10525	COG2186	Transcriptional regulator
AMK01_RS10535	COG2113	Glycine betaine
AMK01_RS10540	COG4176	ABC-type proline glycine betaine transport system permease component
AMK01_RS10545	COG4175	Glycine betaine
AMK01_RS10545	COG0517	IMP dehydrogenase activity
AMK01_RS10550	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AMK01_RS10555	COG1312	Catalyzes the dehydration of D-mannonate
AMK01_RS10560	COG2186	Transcriptional regulator
AMK01_RS10565	COG0747	negative chemotaxis
AMK01_RS10570	COG0601	transmembrane transport
AMK01_RS10575	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AMK01_RS10580	COG0444	Belongs to the ABC transporter superfamily
AMK01_RS10585	COG4608	Belongs to the ABC transporter superfamily
AMK01_RS10590	COG0431	NADPH-dependent FMN reductase
AMK01_RS10595	COG1609	Transcriptional regulator
AMK01_RS10610	COG1175	transmembrane transport
AMK01_RS10615	COG0395	ABC-type sugar transport system, permease component
AMK01_RS10645	COG0577	efflux transmembrane transporter activity
AMK01_RS10645	COG1136	(ABC) transporter
AMK01_RS10650	COG1136	(ABC) transporter
AMK01_RS10650	COG0577	efflux transmembrane transporter activity
AMK01_RS10670	COG1183	phosphatidylcholine synthase activity
AMK01_RS10680	COG3845	ABC transporter
AMK01_RS10690	COG1079	Belongs to the binding-protein-dependent transport system permease family
AMK01_RS10700	COG1879	ABC-type sugar transport system periplasmic component
AMK01_RS10705	COG1129	ABC transporter
AMK01_RS10710	COG1172	Belongs to the binding-protein-dependent transport system permease family
AMK01_RS10715	COG1172	Belongs to the binding-protein-dependent transport system permease family
AMK01_RS10720	COG2186	Transcriptional regulator
AMK01_RS10725	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AMK01_RS10730	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AMK01_RS10740	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AMK01_RS10750	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AMK01_RS10760	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AMK01_RS10760	COG0237	dephospho-CoA kinase activity
AMK01_RS10770	COG4166	transmembrane transport
AMK01_RS10785	COG0174	glutamine synthetase
AMK01_RS10790	COG0347	Belongs to the P(II) protein family
AMK01_RS10800	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AMK01_RS10800	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AMK01_RS10810	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AMK01_RS10815	COG0629	single-stranded DNA binding
AMK01_RS10825	COG2095	MarC family integral membrane protein
AMK01_RS10830	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AMK01_RS10845	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AMK01_RS10860	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AMK01_RS10865	COG0343	queuine tRNA-ribosyltransferase activity
AMK01_RS10875	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AMK01_RS10890	COG0483	inositol monophosphate 1-phosphatase activity
AMK01_RS10895	COG3842	ATPase activity
AMK01_RS10905	COG1840	ABC-type Fe3 transport system, periplasmic component
AMK01_RS10910	COG1840	ABC-type Fe3 transport system, periplasmic component
AMK01_RS10920	COG0784	Response regulator, receiver
AMK01_RS10920	COG4191	Histidine kinase
AMK01_RS10980	COG1802	Transcriptional regulator
AMK01_RS10995	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AMK01_RS11015	COG2801	Transposase and inactivated derivatives
AMK01_RS11025	COG0668	transmembrane transport
AMK01_RS11040	COG0861	Integral membrane protein TerC family
AMK01_RS11045	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AMK01_RS11045	COG0321	lipoyl(octanoyl) transferase activity
AMK01_RS11050	COG0084	hydrolase, TatD family'
AMK01_RS11055	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMK01_RS11060	COG0730	response to heat
AMK01_RS11070	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AMK01_RS11140	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AMK01_RS11145	COG0134	indole-3-glycerol-phosphate synthase activity
AMK01_RS11150	COG0315	cyclic pyranopterin monophosphate synthase activity
AMK01_RS11170	COG0513	Belongs to the DEAD box helicase family
AMK01_RS11185	COG0372	Belongs to the citrate synthase family
AMK01_RS11190	COG0372	Belongs to the citrate synthase family
AMK01_RS11195	COG0504	CTP synthase activity
AMK01_RS11205	COG0149	triose-phosphate isomerase activity
AMK01_RS11215	COG0187	DNA topoisomerase II activity
AMK01_RS11225	COG0628	permease
AMK01_RS11260	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AMK01_RS11270	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AMK01_RS11275	COG0822	iron-sulfur transferase activity
AMK01_RS11280	COG0302	gtp cyclohydrolase
AMK01_RS11285	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AMK01_RS11290	COG1752	Esterase of the alpha-beta hydrolase superfamily
AMK01_RS11315	COG2267	carboxylic ester hydrolase activity
AMK01_RS11330	COG1686	Belongs to the peptidase S11 family
AMK01_RS11345	COG1760	l-serine dehydratase
AMK01_RS11365	COG2239	Acts as a magnesium transporter
AMK01_RS11370	COG0242	peptide deformylase activity
AMK01_RS11395	COG0321	lipoyl(octanoyl) transferase activity
AMK01_RS11410	COG4770	biotin carboxylase activity
AMK01_RS11415	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AMK01_RS11420	COG2153	protein acetylation
AMK01_RS11425	COG1671	Belongs to the UPF0178 family
AMK01_RS11435	COG2259	Doxx family
AMK01_RS11440	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AMK01_RS11455	COG0546	phosphoglycolate phosphatase activity
AMK01_RS11465	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AMK01_RS11485	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AMK01_RS11490	COG0509	glycine decarboxylation via glycine cleavage system
AMK01_RS11495	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AMK01_RS11495	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AMK01_RS11510	COG0316	Belongs to the HesB IscA family
AMK01_RS11515	COG2151	metal-sulfur cluster biosynthetic enzyme
AMK01_RS11520	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AMK01_RS11525	COG0719	Fe-S assembly protein
AMK01_RS11530	COG0396	ATPase activity
AMK01_RS11540	COG0719	Fe-S assembly protein
AMK01_RS11550	COG2945	thiolester hydrolase activity
AMK01_RS11560	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AMK01_RS11565	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AMK01_RS11585	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AMK01_RS11590	COG2833	Protein of unknown function (DUF455)
AMK01_RS11595	COG0741	lytic transglycosylase activity
AMK01_RS11595	COG0739	heme binding
AMK01_RS11595	COG1196	nuclear chromosome segregation
AMK01_RS11600	COG0513	Belongs to the DEAD box helicase family
AMK01_RS11615	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AMK01_RS11640	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AMK01_RS11670	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AMK01_RS11675	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AMK01_RS11680	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
AMK01_RS11685	COG0047	phosphoribosylformylglycinamidine synthase activity
AMK01_RS11700	COG2186	Transcriptional regulator
AMK01_RS11710	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AMK01_RS11720	COG0673	inositol 2-dehydrogenase activity
AMK01_RS11725	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AMK01_RS11735	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AMK01_RS11740	COG1126	abc transporter atp-binding protein
AMK01_RS11745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMK01_RS11750	COG0765	amino acid transport
AMK01_RS11770	COG3485	protocatechuate 3,4-dioxygenase
AMK01_RS11775	COG3971	2-oxopent-4-enoate hydratase activity
AMK01_RS11805	COG2814	Major facilitator Superfamily
AMK01_RS11810	COG2814	Major facilitator Superfamily
AMK01_RS11820	COG0483	inositol monophosphate 1-phosphatase activity
AMK01_RS11825	COG0483	inositol monophosphate 1-phosphatase activity
AMK01_RS11830	COG0037	tRNA processing
AMK01_RS11835	COG2066	Belongs to the glutaminase family
AMK01_RS11840	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AMK01_RS11850	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AMK01_RS11855	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AMK01_RS11870	COG0538	isocitrate dehydrogenase activity
AMK01_RS11895	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AMK01_RS11900	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AMK01_RS11910	COG2313	pseudouridylate synthase activity
AMK01_RS11940	COG3106	COG3106 Predicted ATPase
AMK01_RS11945	COG3768	UPF0283 membrane protein
AMK01_RS11955	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AMK01_RS11975	COG0633	Ferredoxin
AMK01_RS12000	COG1686	Belongs to the peptidase S11 family
AMK01_RS12015	COG1127	ABC transporter
AMK01_RS12025	COG4948	Mandelate Racemase Muconate Lactonizing
AMK01_RS12030	COG2814	Major facilitator Superfamily
AMK01_RS12055	COG0280	phosphate acetyltransferase
AMK01_RS12055	COG0281	malic enzyme
AMK01_RS12070	COG4941	Belongs to the sigma-70 factor family
AMK01_RS12075	COG3795	YCII-related domain
AMK01_RS12085	COG0778	Nitroreductase
AMK01_RS12090	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AMK01_RS12095	COG0823	Involved in the tonB-independent uptake of proteins
AMK01_RS12115	COG1132	(ABC) transporter
AMK01_RS12120	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AMK01_RS12140	COG1254	Belongs to the acylphosphatase family
AMK01_RS12150	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AMK01_RS12155	COG0546	phosphoglycolate phosphatase activity
AMK01_RS12160	COG2989	Protein conserved in bacteria
AMK01_RS12165	COG0114	fumarate hydratase activity
AMK01_RS12175	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AMK01_RS12175	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AMK01_RS12180	COG3706	GGDEF domain
AMK01_RS12195	COG1846	Transcriptional regulator
AMK01_RS12210	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AMK01_RS12215	COG2226	methyltransferase
AMK01_RS12225	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMK01_RS12230	COG1120	ATPase activity
AMK01_RS12235	COG2390	Transcriptional regulator
AMK01_RS12240	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AMK01_RS12245	COG3958	Transketolase
AMK01_RS12250	COG3959	Transketolase, thiamine diphosphate binding domain
AMK01_RS12255	COG1172	Belongs to the binding-protein-dependent transport system permease family
AMK01_RS12260	COG1879	ABC-type sugar transport system periplasmic component
AMK01_RS12265	COG1129	ABC transporter
AMK01_RS12270	COG1028	Short-chain dehydrogenase reductase Sdr
AMK01_RS12275	COG1028	Short-chain dehydrogenase reductase Sdr
AMK01_RS12280	COG1028	Short-chain dehydrogenase reductase Sdr
AMK01_RS12290	COG0746	molybdenum cofactor guanylyltransferase activity
AMK01_RS12295	COG1763	Mo-molybdopterin cofactor biosynthetic process
AMK01_RS12310	COG0667	Aldo Keto reductase
AMK01_RS12320	COG1764	response to oxidative stress
AMK01_RS12325	COG2205	protein histidine kinase activity
AMK01_RS12355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMK01_RS12360	COG4215	(ABC) transporter
AMK01_RS12370	COG5425	PFAM Usg family protein
AMK01_RS12435	COG2084	Dehydrogenase
AMK01_RS12450	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
AMK01_RS12455	COG0583	DNA-binding transcription factor activity
AMK01_RS12465	COG1522	sequence-specific DNA binding
AMK01_RS12470	COG1573	uracil-dna glycosylase
AMK01_RS12480	COG2202	Pas domain
AMK01_RS12480	COG2205	protein histidine kinase activity
AMK01_RS12490	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AMK01_RS12495	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AMK01_RS12510	COG2814	Major facilitator Superfamily
AMK01_RS12525	COG1028	Short-chain dehydrogenase reductase Sdr
AMK01_RS12530	COG0842	Transport permease protein
AMK01_RS12535	COG1131	(ABC) transporter
AMK01_RS12545	COG3507	Belongs to the glycosyl hydrolase 43 family
AMK01_RS12550	COG0667	Aldo Keto reductase
AMK01_RS12575	COG0395	ABC-type sugar transport system, permease component
AMK01_RS12580	COG1175	transmembrane transport
AMK01_RS12620	COG0277	FAD linked oxidase domain protein
AMK01_RS12625	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AMK01_RS12660	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AMK01_RS12670	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AMK01_RS12675	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AMK01_RS12760	COG1492	cobalamin metabolic process
AMK01_RS12780	COG0583	DNA-binding transcription factor activity
AMK01_RS12800	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AMK01_RS12805	COG1285	pathogenesis
AMK01_RS12825	COG1566	PFAM secretion protein HlyD family protein
AMK01_RS12840	COG0668	transmembrane transport
AMK01_RS12885	COG0745	RESPONSE REGULATOR receiver
AMK01_RS12900	COG0640	Transcriptional regulator
AMK01_RS12910	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AMK01_RS12915	COG1393	Belongs to the ArsC family
AMK01_RS12920	COG0431	NADPH-dependent FMN reductase
AMK01_RS12935	COG3264	Mechanosensitive ion channel
AMK01_RS12935	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AMK01_RS12945	COG0745	RESPONSE REGULATOR receiver
AMK01_RS12950	COG2814	Major facilitator Superfamily
AMK01_RS12960	COG1175	transmembrane transport
AMK01_RS12965	COG0395	ABC-type sugar transport system, permease component
AMK01_RS12980	COG3842	ATPase activity
AMK01_RS12990	COG1461	Dihydroxyacetone kinase
AMK01_RS12995	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
AMK01_RS13015	COG2376	Dihydroxyacetone kinase
AMK01_RS13025	COG1846	Transcriptional regulator
AMK01_RS13040	COG1764	response to oxidative stress
AMK01_RS13080	COG1607	acyl-coa hydrolase
AMK01_RS13105	COG0702	epimerase
AMK01_RS13120	COG0784	Response regulator, receiver
AMK01_RS13125	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMK01_RS13145	COG3152	Membrane
AMK01_RS13155	COG0556	nucleotide-excision repair
AMK01_RS13170	COG2135	peptidase activity
AMK01_RS13175	COG0456	acetyltransferase
AMK01_RS13190	COG1278	Cold shock
AMK01_RS13195	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AMK01_RS13200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AMK01_RS13230	COG5002	protein histidine kinase activity
AMK01_RS13235	COG0745	RESPONSE REGULATOR receiver
AMK01_RS13285	COG2354	Protein conserved in bacteria
AMK01_RS13295	COG0702	epimerase
AMK01_RS13300	COG0137	argininosuccinate synthase activity
AMK01_RS13330	COG0456	acetyltransferase
AMK01_RS13340	COG1917	Cupin 2, conserved barrel domain protein
AMK01_RS13340	COG2207	Transcriptional regulator
AMK01_RS13370	COG3158	transport of potassium into the cell
AMK01_RS13400	COG1136	(ABC) transporter
AMK01_RS13410	COG1917	Cupin 2, conserved barrel domain protein
AMK01_RS13410	COG2207	Transcriptional regulator
AMK01_RS13425	COG1845	cytochrome c oxidase, subunit III
AMK01_RS13430	COG1845	cytochrome c oxidase, subunit III
AMK01_RS13435	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AMK01_RS13440	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AMK01_RS13460	COG3453	Protein conserved in bacteria
AMK01_RS13460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AMK01_RS13485	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AMK01_RS13580	COG5001	Diguanylate cyclase
AMK01_RS13580	COG3300	MHYT domain
AMK01_RS13595	COG2208	phosphoserine phosphatase activity
AMK01_RS13630	COG1063	alcohol dehydrogenase
AMK01_RS13650	COG0395	ABC-type sugar transport system, permease component
AMK01_RS13665	COG1846	Transcriptional regulator
AMK01_RS13665	COG1940	carbohydrate kinase activity
AMK01_RS13685	COG0697	spore germination
AMK01_RS13690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AMK01_RS13695	COG2204	response regulator
AMK01_RS13700	COG4191	Histidine kinase
AMK01_RS13740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMK01_RS13760	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AMK01_RS13895	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AMK01_RS13900	COG1121	(ABC) transporter
AMK01_RS13925	COG1253	flavin adenine dinucleotide binding
AMK01_RS13955	COG0384	phenazine biosynthesis protein PhzF
AMK01_RS13980	COG0395	ABC-type sugar transport system, permease component
AMK01_RS13995	COG1846	Transcriptional regulator
AMK01_RS14000	COG0667	Aldo Keto reductase
AMK01_RS14005	COG5634	Uncharacterized conserved protein (DUF2278)
AMK01_RS14010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AMK01_RS14015	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AMK01_RS14065	COG1260	myo-inositol-1-phosphate synthase
AMK01_RS14090	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AMK01_RS14105	COG1069	ribulokinase activity
AMK01_RS14110	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AMK01_RS14125	COG1175	transmembrane transport
AMK01_RS14135	COG3842	ATPase activity
AMK01_RS14150	COG0463	Glycosyl transferase, family 2
AMK01_RS14155	COG2207	Transcriptional regulator
AMK01_RS14160	COG1064	alcohol dehydrogenase
AMK01_RS14175	COG1522	sequence-specific DNA binding
AMK01_RS14180	COG1794	racemase activity, acting on amino acids and derivatives
AMK01_RS14185	COG1846	Transcriptional regulator
AMK01_RS14185	COG0456	acetyltransferase
AMK01_RS14190	COG1309	transcriptional regulator
AMK01_RS14195	COG2814	Major facilitator Superfamily
AMK01_RS14200	COG1733	regulation of RNA biosynthetic process
AMK01_RS14210	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AMK01_RS14220	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AMK01_RS14245	COG0668	transmembrane transport
AMK01_RS14300	COG0656	L-ascorbic acid biosynthetic process
AMK01_RS14305	COG0440	acetolactate synthase activity
AMK01_RS14310	COG0028	Belongs to the TPP enzyme family
AMK01_RS14320	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AMK01_RS14335	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AMK01_RS14340	COG3830	Belongs to the UPF0237 family
AMK01_RS14340	COG0560	Phosphoserine phosphatase
AMK01_RS14345	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AMK01_RS14350	COG0330	HflC and HflK could
AMK01_RS14355	COG0330	HflC and HflK could
AMK01_RS14365	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AMK01_RS14395	COG0277	FAD linked oxidase domain protein
AMK01_RS14400	COG0667	Aldo Keto reductase
AMK01_RS14410	COG3180	Ammonia monooxygenase
AMK01_RS14425	COG2885	chlorophyll binding
AMK01_RS14430	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AMK01_RS14435	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMK01_RS14450	COG2719	SpoVR family
AMK01_RS14455	COG2718	Belongs to the UPF0229 family
AMK01_RS14460	COG2766	serine protein kinase
AMK01_RS14480	COG1335	isochorismatase
AMK01_RS14505	COG0006	proline dipeptidase activity
AMK01_RS14520	COG2264	protein methyltransferase activity
AMK01_RS14525	COG1999	signal sequence binding
AMK01_RS14530	COG0840	transmembrane signaling receptor activity
AMK01_RS14530	COG2972	Histidine kinase
AMK01_RS14535	COG0835	chemotaxis
AMK01_RS14555	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AMK01_RS14570	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AMK01_RS14580	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AMK01_RS14585	COG0849	cell division
AMK01_RS14590	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AMK01_RS14595	COG1181	Belongs to the D-alanine--D-alanine ligase family
AMK01_RS14605	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AMK01_RS14610	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AMK01_RS14615	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AMK01_RS14625	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AMK01_RS14630	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AMK01_RS14640	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AMK01_RS14655	COG0275	rRNA processing
AMK01_RS14660	COG2001	Belongs to the MraZ family
AMK01_RS14685	COG3023	N-Acetylmuramoyl-L-alanine amidase
AMK01_RS14690	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AMK01_RS14700	COG1280	lysine exporter protein (LysE YggA)
AMK01_RS14725	COG3757	hydrolase, family 25
AMK01_RS14740	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AMK01_RS14760	COG2267	carboxylic ester hydrolase activity
AMK01_RS14765	COG0697	spore germination
AMK01_RS14770	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AMK01_RS14775	COG0028	Belongs to the TPP enzyme family
AMK01_RS14780	COG0251	oxidation-reduction process
AMK01_RS14795	COG1376	ErfK ybiS ycfS ynhG family protein
AMK01_RS14800	COG1192	Involved in chromosome partitioning
AMK01_RS14815	COG0174	glutamine synthetase
AMK01_RS14845	COG2011	ABC-type metal ion transport system permease component
AMK01_RS14850	COG3842	ATPase activity
AMK01_RS14860	COG0673	inositol 2-dehydrogenase activity
AMK01_RS14865	COG0395	ABC-type sugar transport system, permease component
AMK01_RS14870	COG1175	transmembrane transport
AMK01_RS14880	COG2971	BadF BadG BcrA BcrD
AMK01_RS14885	COG2188	Transcriptional regulator
AMK01_RS14910	COG4702	Belongs to the UPF0303 family
AMK01_RS14915	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AMK01_RS14925	COG0395	ABC-type sugar transport system, permease component
AMK01_RS14930	COG1176	ABC-type spermidine putrescine transport system, permease component I
AMK01_RS14940	COG3842	ATPase activity
AMK01_RS15025	COG2968	Membrane
AMK01_RS15040	COG0432	Pfam Uncharacterised protein family UPF0047
AMK01_RS15070	COG2207	Transcriptional regulator
AMK01_RS15070	COG1917	Cupin 2, conserved barrel domain protein
AMK01_RS15090	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AMK01_RS15100	COG1063	alcohol dehydrogenase
AMK01_RS15105	COG0156	8-amino-7-oxononanoate synthase activity
AMK01_RS15115	COG0358	DNA primase activity
AMK01_RS15130	COG0505	Belongs to the CarA family
AMK01_RS15145	COG0534	Mate efflux family protein
AMK01_RS15155	COG0667	Aldo Keto reductase
AMK01_RS15160	COG2321	neutral zinc metallopeptidase
AMK01_RS15170	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AMK01_RS15185	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AMK01_RS15195	COG1301	dicarboxylic acid transport
AMK01_RS15200	COG4191	Histidine kinase
AMK01_RS15205	COG2204	response regulator
AMK01_RS15210	COG1522	sequence-specific DNA binding
AMK01_RS15215	COG0492	ferredoxin-NADP+ reductase activity
AMK01_RS15220	COG0583	DNA-binding transcription factor activity
AMK01_RS15230	COG2814	Major facilitator Superfamily
AMK01_RS15235	COG1902	pentaerythritol trinitrate reductase activity
AMK01_RS15250	COG0583	DNA-binding transcription factor activity
AMK01_RS15255	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AMK01_RS15255	COG0456	acetyltransferase
AMK01_RS15265	COG0387	Pfam Sodium calcium exchanger
AMK01_RS15280	COG1442	glycosyl transferase family 8
AMK01_RS15310	COG2133	pyrroloquinoline quinone binding
AMK01_RS15325	COG1278	Cold shock
AMK01_RS15340	COG0745	RESPONSE REGULATOR receiver
AMK01_RS15345	COG1846	Transcriptional regulator
AMK01_RS15365	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AMK01_RS15370	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMK01_RS15390	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AMK01_RS15400	COG1496	oxidoreductase activity
AMK01_RS15415	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AMK01_RS15425	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AMK01_RS15430	COG3300	MHYT domain
AMK01_RS15430	COG5001	Diguanylate cyclase
AMK01_RS15440	COG0193	aminoacyl-tRNA hydrolase activity
AMK01_RS15450	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AMK01_RS15475	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AMK01_RS15480	COG2857	Cytochrome c1
AMK01_RS15480	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AMK01_RS15500	COG1132	(ABC) transporter
AMK01_RS15510	COG1132	(ABC) transporter
AMK01_RS15515	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AMK01_RS15520	COG1283	sodium-dependent phosphate transmembrane transporter activity
AMK01_RS15530	COG0408	coproporphyrinogen oxidase activity
AMK01_RS15545	COG0617	tRNA 3'-terminal CCA addition
AMK01_RS15560	COG0714	Associated with various cellular activities
AMK01_RS15580	COG0454	-acetyltransferase
AMK01_RS15590	COG0435	Glutathione S-transferase
AMK01_RS15620	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AMK01_RS15625	COG3135	benzoate transporter
AMK01_RS15630	COG0740	serine-type endopeptidase activity
AMK01_RS15635	COG3416	Protein conserved in bacteria
AMK01_RS15640	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AMK01_RS15645	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AMK01_RS15660	COG0512	Glutamine amidotransferase of anthranilate synthase
AMK01_RS15660	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AMK01_RS15675	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AMK01_RS15685	COG2197	response regulator
AMK01_RS15705	COG1435	thymidine kinase activity
AMK01_RS15720	COG4175	Glycine betaine
AMK01_RS15735	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AMK01_RS15755	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AMK01_RS15760	COG0366	Alpha amylase catalytic
AMK01_RS15770	COG0601	transmembrane transport
AMK01_RS15775	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AMK01_RS15785	COG4608	Belongs to the ABC transporter superfamily
AMK01_RS15795	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AMK01_RS15815	COG1160	GTP binding
AMK01_RS15835	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AMK01_RS15855	COG0024	Methionine aminopeptidase
AMK01_RS15870	COG4941	Belongs to the sigma-70 factor family
AMK01_RS15875	COG3795	YCII-related domain
AMK01_RS15885	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AMK01_RS15890	COG1028	Short-chain dehydrogenase reductase Sdr
AMK01_RS15900	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AMK01_RS15915	COG0583	DNA-binding transcription factor activity
AMK01_RS15930	COG0402	S-adenosylhomocysteine deaminase activity
AMK01_RS15945	COG0671	phosphoesterase, PA-phosphatase related
AMK01_RS15945	COG2453	phosphatase
AMK01_RS15950	COG2267	carboxylic ester hydrolase activity
AMK01_RS15955	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AMK01_RS15960	COG1842	Phage shock protein A
AMK01_RS15970	COG2268	Band 7 protein
AMK01_RS15980	COG2351	hydroxyisourate hydrolase activity
AMK01_RS15985	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
AMK01_RS16015	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AMK01_RS16015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AMK01_RS16020	COG5002	protein histidine kinase activity
AMK01_RS16020	COG2205	protein histidine kinase activity
AMK01_RS16020	COG0784	Response regulator, receiver
AMK01_RS16030	COG0477	Major facilitator Superfamily
AMK01_RS16035	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AMK01_RS16040	COG1609	Transcriptional regulator
AMK01_RS16045	COG4335	DNA alkylation repair
AMK01_RS16050	COG0513	Belongs to the DEAD box helicase family
AMK01_RS16070	COG2308	Evidence 4 Homologs of previously reported genes of
AMK01_RS16095	COG0129	dihydroxy-acid dehydratase activity
AMK01_RS16100	COG1012	belongs to the aldehyde dehydrogenase family
AMK01_RS16110	COG4214	carbohydrate transport
AMK01_RS16145	COG0673	inositol 2-dehydrogenase activity
AMK01_RS16155	COG4213	ABC transporter substrate-binding protein
AMK01_RS16160	COG4214	carbohydrate transport
AMK01_RS16165	COG1129	ABC transporter
AMK01_RS16205	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AMK01_RS16210	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AMK01_RS16270	COG2856	Zn peptidase
AMK01_RS16375	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AMK01_RS16395	COG0346	lactoylglutathione lyase activity
AMK01_RS16400	COG0583	DNA-binding transcription factor activity
AMK01_RS16410	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AMK01_RS16415	COG2755	lipolytic protein G-D-S-L family
AMK01_RS16415	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AMK01_RS16425	COG0723	plastoquinol--plastocyanin reductase activity
AMK01_RS16430	COG3108	Peptidase M15
AMK01_RS16465	COG1172	Belongs to the binding-protein-dependent transport system permease family
AMK01_RS16470	COG1129	ABC transporter
AMK01_RS16495	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMK01_RS16505	COG1215	transferase activity, transferring glycosyl groups
AMK01_RS16510	COG1216	Glycosyl transferase, family 2
AMK01_RS16520	COG1442	glycosyl transferase family 8
AMK01_RS16520	COG1216	Glycosyl transferase, family 2
AMK01_RS16555	COG1396	sequence-specific DNA binding
AMK01_RS16610	COG0463	Glycosyl transferase, family 2
AMK01_RS16615	COG1215	transferase activity, transferring glycosyl groups
AMK01_RS16650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMK01_RS16655	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
AMK01_RS16675	COG0489	protein tyrosine kinase activity
AMK01_RS16675	COG3206	protein involved in exopolysaccharide biosynthesis
AMK01_RS16700	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AMK01_RS16705	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AMK01_RS16715	COG0400	carboxylic ester hydrolase activity
AMK01_RS16720	COG0346	lactoylglutathione lyase activity
AMK01_RS16725	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AMK01_RS16730	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AMK01_RS16735	COG0662	Cupin 2, conserved barrel domain protein
AMK01_RS16735	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AMK01_RS16750	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMK01_RS16760	COG1309	transcriptional regulator
AMK01_RS16765	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMK01_RS16770	COG1131	(ABC) transporter
AMK01_RS16775	COG0842	Transport permease protein
AMK01_RS16780	COG0842	Transport permease protein
AMK01_RS16800	COG2076	Multidrug Resistance protein
AMK01_RS16810	COG2346	COG2346, Truncated hemoglobins
AMK01_RS16835	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AMK01_RS16865	COG0784	Response regulator, receiver
AMK01_RS16885	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AMK01_RS16895	COG0366	Alpha amylase catalytic
AMK01_RS16900	COG4977	sequence-specific DNA binding
AMK01_RS16910	COG1309	transcriptional regulator
AMK01_RS16920	COG2852	Protein conserved in bacteria
AMK01_RS16940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AMK01_RS16945	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AMK01_RS16950	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AMK01_RS16965	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AMK01_RS16970	COG0830	nickel cation binding
AMK01_RS16975	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AMK01_RS16980	COG3706	GGDEF domain
AMK01_RS16990	COG0804	urea catabolic process
AMK01_RS16995	COG1442	glycosyl transferase family 8
AMK01_RS17000	COG3755	Protein conserved in bacteria
AMK01_RS17005	COG0832	Belongs to the urease beta subunit family
AMK01_RS17010	COG3813	Protein conserved in bacteria
AMK01_RS17020	COG0829	nickel cation binding
AMK01_RS17060	COG2205	protein histidine kinase activity
AMK01_RS17060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMK01_RS17070	COG0683	leucine binding
AMK01_RS17095	COG0559	Belongs to the binding-protein-dependent transport system permease family
AMK01_RS17180	COG0564	pseudouridine synthase activity
AMK01_RS17185	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AMK01_RS17195	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AMK01_RS17210	COG0129	dihydroxy-acid dehydratase activity
AMK01_RS17225	COG0657	acetylesterase activity
AMK01_RS17235	COG1028	Short-chain dehydrogenase reductase Sdr
AMK01_RS17250	COG2094	Belongs to the DNA glycosylase MPG family
AMK01_RS17275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMK01_RS17285	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AMK01_RS17295	COG1959	2 iron, 2 sulfur cluster binding
AMK01_RS17300	COG1028	Short-chain dehydrogenase reductase Sdr
AMK01_RS17320	COG3842	ATPase activity
AMK01_RS17325	COG0395	ABC-type sugar transport system, permease component
AMK01_RS17330	COG1175	transmembrane transport
AMK01_RS17335	COG1653	transport
AMK01_RS17340	COG1940	carbohydrate kinase activity
AMK01_RS17340	COG1846	Transcriptional regulator
AMK01_RS17345	COG1653	transport
AMK01_RS17380	COG2244	polysaccharide biosynthetic process
AMK01_RS17385	COG0438	transferase activity, transferring glycosyl groups
AMK01_RS17405	COG0489	protein tyrosine kinase activity
AMK01_RS17415	COG1596	polysaccharide export
AMK01_RS17455	COG2132	Multicopper oxidase
AMK01_RS17470	COG0713	ATP synthesis coupled electron transport
AMK01_RS17475	COG0651	ATP synthesis coupled electron transport
AMK01_RS17485	COG0651	ATP synthesis coupled electron transport
AMK01_RS17505	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMK01_RS17510	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMK01_RS17515	COG0649	NAD binding
AMK01_RS17540	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMK01_RS17545	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AMK01_RS17590	COG1187	pseudouridine synthase activity
AMK01_RS17600	COG3273	potassium ion transport
AMK01_RS17600	COG0471	metal ion transport
AMK01_RS17605	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AMK01_RS17610	COG1309	transcriptional regulator
AMK01_RS17620	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMK01_RS17640	COG1176	ABC-type spermidine putrescine transport system, permease component I
AMK01_RS17645	COG1177	transmembrane transport
AMK01_RS17660	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AMK01_RS17680	COG1028	Short-chain dehydrogenase reductase Sdr
AMK01_RS17685	COG0277	FAD linked oxidase domain protein
AMK01_RS17695	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AMK01_RS17700	COG1473	amidohydrolase
AMK01_RS17730	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AMK01_RS17755	COG3300	MHYT domain
AMK01_RS17755	COG5001	Diguanylate cyclase
AMK01_RS17760	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AMK01_RS17765	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AMK01_RS17780	COG0683	leucine binding
AMK01_RS17820	COG0482	sulfurtransferase activity
AMK01_RS17830	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AMK01_RS17845	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AMK01_RS17850	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AMK01_RS17855	COG0037	tRNA processing
AMK01_RS17865	COG2885	chlorophyll binding
AMK01_RS17870	COG0823	Involved in the tonB-independent uptake of proteins
AMK01_RS17880	COG0848	biopolymer transport protein
AMK01_RS17890	COG0824	Thioesterase
AMK01_RS17915	COG1692	metallophosphoesterase
AMK01_RS17930	COG0217	transcriptional regulatory protein
AMK01_RS17935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMK01_RS17940	COG0840	transmembrane signaling receptor activity
AMK01_RS17945	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AMK01_RS17960	COG0632	four-way junction helicase activity
AMK01_RS17965	COG2255	four-way junction helicase activity
AMK01_RS17970	COG1408	metallophosphoesterase
AMK01_RS17975	COG0494	nUDIX hydrolase
AMK01_RS17980	COG2318	DinB family
AMK01_RS17990	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AMK01_RS17990	COG0392	lysyltransferase activity
AMK01_RS18000	COG0668	transmembrane transport
AMK01_RS18005	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AMK01_RS18070	COG0126	phosphoglycerate kinase activity
AMK01_RS18075	COG3588	fructose-bisphosphate aldolase
AMK01_RS18080	COG0384	phenazine biosynthesis protein PhzF
AMK01_RS18100	COG0254	rRNA binding
AMK01_RS18105	COG1132	(ABC) transporter
AMK01_RS18115	COG3422	double-strand break repair
AMK01_RS18140	COG0483	inositol monophosphate 1-phosphatase activity
AMK01_RS18145	COG2201	protein-glutamate methylesterase activity
AMK01_RS18155	COG0835	chemotaxis
AMK01_RS18165	COG0840	transmembrane signaling receptor activity
AMK01_RS18170	COG0835	chemotaxis
AMK01_RS18210	COG0640	Transcriptional regulator
AMK01_RS18225	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AMK01_RS18230	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AMK01_RS18235	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AMK01_RS18240	COG0457	Tetratricopeptide repeat
AMK01_RS18260	COG0583	DNA-binding transcription factor activity
AMK01_RS18265	COG1942	4-Oxalocrotonate Tautomerase
AMK01_RS18275	COG1280	lysine exporter protein (LysE YggA)
AMK01_RS18280	COG0469	pyruvate kinase activity
AMK01_RS18300	COG3750	Belongs to the UPF0335 family
AMK01_RS18305	COG3108	Peptidase M15
AMK01_RS18335	COG5310	Homospermidine synthase
AMK01_RS18340	COG0737	Belongs to the 5'-nucleotidase family
AMK01_RS18345	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AMK01_RS18350	COG0330	HflC and HflK could
AMK01_RS18370	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AMK01_RS18375	COG2951	lytic endotransglycosylase activity
AMK01_RS18395	COG0070	glutamate synthase
AMK01_RS18395	COG0069	glutamate synthase activity
AMK01_RS18395	COG0067	glutamate synthase
AMK01_RS18415	COG0071	Belongs to the small heat shock protein (HSP20) family
AMK01_RS18520	COG2308	Evidence 4 Homologs of previously reported genes of
AMK01_RS18520	COG2307	Protein conserved in bacteria
AMK01_RS18535	COG0058	SHG alpha-glucan phosphorylase activity
AMK01_RS18540	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AMK01_RS18545	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AMK01_RS18550	COG0297	glycogen (starch) synthase activity
AMK01_RS18555	COG0033	Phosphoglucomutase
AMK01_RS18580	COG0446	pyridine nucleotide-disulphide oxidoreductase
AMK01_RS18580	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AMK01_RS18590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AMK01_RS18615	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AMK01_RS18625	COG2202	Pas domain
AMK01_RS18625	COG3920	Histidine kinase
AMK01_RS18660	COG5001	Diguanylate cyclase
AMK01_RS18675	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AMK01_RS18680	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AMK01_RS18685	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AMK01_RS18690	COG1609	Transcriptional regulator
AMK01_RS18695	COG1846	Transcriptional regulator
AMK01_RS18705	COG0523	cobalamin synthesis protein
AMK01_RS18725	COG3706	GGDEF domain
AMK01_RS18745	COG0583	DNA-binding transcription factor activity
AMK01_RS18775	COG0800	Aldolase
AMK01_RS18780	COG2954	triphosphatase activity
AMK01_RS18790	COG1054	Belongs to the UPF0176 family
AMK01_RS18810	COG0673	inositol 2-dehydrogenase activity
AMK01_RS18820	COG1879	ABC-type sugar transport system periplasmic component
AMK01_RS18825	COG1172	Belongs to the binding-protein-dependent transport system permease family
AMK01_RS18830	COG1129	ABC transporter
AMK01_RS18835	COG1609	Transcriptional regulator
AMK01_RS18840	COG2115	Belongs to the xylose isomerase family
AMK01_RS18845	COG1070	Carbohydrate kinase
AMK01_RS18850	COG1609	Transcriptional regulator
AMK01_RS18875	COG1253	flavin adenine dinucleotide binding
AMK01_RS18880	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AMK01_RS18885	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AMK01_RS18895	COG0583	DNA-binding transcription factor activity
AMK01_RS18900	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AMK01_RS18905	COG3842	ATPase activity
AMK01_RS18910	COG1176	ABC-type spermidine putrescine transport system, permease component I
AMK01_RS18915	COG1177	transmembrane transport
AMK01_RS18920	COG1012	belongs to the aldehyde dehydrogenase family
AMK01_RS18945	COG1595	DNA-templated transcription, initiation
AMK01_RS18960	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AMK01_RS19020	COG1175	transmembrane transport
AMK01_RS19040	COG1940	carbohydrate kinase activity
AMK01_RS19065	COG1764	response to oxidative stress
AMK01_RS19070	COG1028	Short-chain dehydrogenase reductase Sdr
AMK01_RS19085	COG1129	ABC transporter
AMK01_RS19095	COG2186	Transcriptional regulator
AMK01_RS19100	COG4948	Mandelate Racemase Muconate Lactonizing
AMK01_RS19110	COG1028	Short-chain dehydrogenase reductase Sdr
AMK01_RS19120	COG1609	Transcriptional regulator
AMK01_RS19130	COG1028	Short-chain dehydrogenase reductase Sdr
AMK01_RS19135	COG3386	PFAM SMP-30 Gluconolaconase
AMK01_RS19145	COG3842	ATPase activity
AMK01_RS19150	COG0395	ABC-type sugar transport system, permease component
AMK01_RS19155	COG1175	transmembrane transport
AMK01_RS19160	COG1653	transport
AMK01_RS19165	COG1609	Transcriptional regulator
AMK01_RS19170	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AMK01_RS19175	COG0720	synthase
AMK01_RS19180	COG0602	queuosine metabolic process
AMK01_RS19190	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AMK01_RS19200	COG1780	Probably involved in ribonucleotide reductase function
AMK01_RS19230	COG1012	belongs to the aldehyde dehydrogenase family
AMK01_RS19240	COG0693	protein deglycase activity
AMK01_RS19255	COG0387	Pfam Sodium calcium exchanger
AMK01_RS19295	COG0542	response to heat
AMK01_RS19305	COG2890	protein-(glutamine-N5) methyltransferase activity
AMK01_RS19310	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AMK01_RS19320	COG0527	aspartate kinase activity
AMK01_RS19325	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AMK01_RS19335	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AMK01_RS19350	COG2267	carboxylic ester hydrolase activity
AMK01_RS19350	COG2226	methyltransferase
AMK01_RS19365	COG0494	nUDIX hydrolase
AMK01_RS19375	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AMK01_RS19380	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AMK01_RS19385	COG0653	protein targeting
AMK01_RS19400	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AMK01_RS19405	COG0667	Aldo Keto reductase
AMK01_RS19435	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AMK01_RS19435	COG4651	solute:proton antiporter activity
AMK01_RS19465	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AMK01_RS19475	COG0300	oxidoreductase activity
AMK01_RS19495	COG2086	electron transfer activity
AMK01_RS19505	COG1250	3-hydroxyacyl-CoA dehydrogenase
AMK01_RS19510	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AMK01_RS19515	COG0165	Argininosuccinate lyase
AMK01_RS19540	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AMK01_RS19540	COG0037	tRNA processing
AMK01_RS19550	COG2884	Cell division ATP-binding protein ftsE
AMK01_RS19570	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AMK01_RS19585	COG0287	Prephenate dehydrogenase
AMK01_RS19590	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AMK01_RS19595	COG2226	methyltransferase
AMK01_RS19600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AMK01_RS19620	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AMK01_RS19630	COG0563	adenylate kinase activity
AMK01_RS19660	COG4536	flavin adenine dinucleotide binding
AMK01_RS19665	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AMK01_RS19670	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AMK01_RS19675	COG4974	Belongs to the 'phage' integrase family
AMK01_RS19680	COG0825	malonyl-CoA metabolic process
AMK01_RS19685	COG3034	peptidoglycan biosynthetic process
AMK01_RS19695	COG0523	cobalamin synthesis protein
AMK01_RS19700	COG1686	Belongs to the peptidase S11 family
AMK01_RS19705	COG1473	amidohydrolase
AMK01_RS19740	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AMK01_RS19760	COG1175	transmembrane transport
AMK01_RS19775	COG0156	8-amino-7-oxononanoate synthase activity
AMK01_RS19785	COG0729	surface antigen
AMK01_RS19800	COG0010	Belongs to the arginase family
AMK01_RS19805	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AMK01_RS19810	COG0835	chemotaxis
AMK01_RS19815	COG2223	nitrite transmembrane transporter activity
AMK01_RS19825	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AMK01_RS19830	COG3383	formate dehydrogenase (NAD+) activity
AMK01_RS19845	COG0583	DNA-binding transcription factor activity
AMK01_RS19850	COG0640	Transcriptional regulator
AMK01_RS19855	COG1028	Short-chain dehydrogenase reductase Sdr
AMK01_RS19860	COG0789	Transcriptional regulator
AMK01_RS19865	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AMK01_RS19870	COG1116	anion transmembrane transporter activity
AMK01_RS19875	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AMK01_RS19890	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AMK01_RS19900	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AMK01_RS19905	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AMK01_RS19910	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AMK01_RS19915	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AMK01_RS19930	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AMK01_RS19945	COG4974	Belongs to the 'phage' integrase family
AMK01_RS19955	COG3038	cytochrome b561
AMK01_RS19970	COG1028	Short-chain dehydrogenase reductase Sdr
AMK01_RS19985	COG0508	dehydrogenase complex catalyzes the overall conversion of
AMK01_RS20000	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AMK01_RS20005	COG0045	succinate-CoA ligase (ADP-forming) activity
AMK01_RS20010	COG0039	L-malate dehydrogenase activity
AMK01_RS20015	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AMK01_RS20020	COG2845	Protein of unknown function (DUF459)
AMK01_RS20065	COG2350	Protein conserved in bacteria
AMK01_RS20070	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AMK01_RS20075	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AMK01_RS20080	COG0181	hydroxymethylbilane synthase activity
AMK01_RS20105	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AMK01_RS20120	COG1872	DUF167
AMK01_RS20125	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AMK01_RS20135	COG1217	gtp-binding protein TYPA
AMK01_RS20140	COG0339	signal peptide processing
AMK01_RS20165	COG0137	argininosuccinate synthase activity
AMK01_RS20185	COG4120	Belongs to the binding-protein-dependent transport system permease family
AMK01_RS20195	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AMK01_RS20205	COG1595	DNA-templated transcription, initiation
AMK01_RS20215	COG2154	pterin-4-alpha-carbinolamine dehydratase
AMK01_RS20225	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AMK01_RS20235	COG4181	ATPase activity
AMK01_RS20245	COG0670	Belongs to the BI1 family
AMK01_RS20265	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AMK01_RS20270	COG4133	protoheme IX ABC transporter activity
AMK01_RS20275	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AMK01_RS20280	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AMK01_RS20300	COG2917	probably involved in intracellular septation
AMK01_RS20305	COG0552	protein localization to endoplasmic reticulum
AMK01_RS20310	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AMK01_RS20315	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AMK01_RS20325	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AMK01_RS20330	COG0287	Prephenate dehydrogenase
AMK01_RS20330	COG1605	Chorismate mutase
AMK01_RS20335	COG0228	four-way junction DNA binding
AMK01_RS20340	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AMK01_RS20345	COG0336	Belongs to the RNA methyltransferase TrmD family
AMK01_RS20350	COG0335	large ribosomal subunit rRNA binding
AMK01_RS20360	COG0765	amino acid transport
AMK01_RS20365	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AMK01_RS20370	COG0656	L-ascorbic acid biosynthetic process
AMK01_RS20380	COG0745	RESPONSE REGULATOR receiver
AMK01_RS20395	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AMK01_RS20400	COG1674	ftsk spoiiie
AMK01_RS20405	COG0004	ammonium transporteR
AMK01_RS20410	COG0347	Belongs to the P(II) protein family
AMK01_RS20415	COG1946	Acyl-CoA thioesterase
AMK01_RS20420	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AMK01_RS20425	COG2835	tetraacyldisaccharide 4'-kinase activity
AMK01_RS20480	COG1129	ABC transporter
AMK01_RS20485	COG4211	Belongs to the binding-protein-dependent transport system permease family
AMK01_RS20500	COG0601	transmembrane transport
AMK01_RS20505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AMK01_RS20510	COG0444	Belongs to the ABC transporter superfamily
AMK01_RS20515	COG4608	Belongs to the ABC transporter superfamily
AMK01_RS20525	COG3459	Glycosyltransferase 36 associated
AMK01_RS20540	COG1132	(ABC) transporter
AMK01_RS20550	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AMK01_RS20560	COG1126	abc transporter atp-binding protein
AMK01_RS20565	COG0765	amino acid transport
AMK01_RS20570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMK01_RS20575	COG1349	DNA-binding transcription factor activity
AMK01_RS20580	COG2223	nitrite transmembrane transporter activity
AMK01_RS20585	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AMK01_RS20590	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AMK01_RS20595	COG0142	geranyltranstransferase activity
AMK01_RS20600	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AMK01_RS20615	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AMK01_RS20625	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
AMK01_RS20630	COG0183	Belongs to the thiolase family
AMK01_RS20660	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AMK01_RS20665	COG1329	Transcriptional regulator
AMK01_RS20670	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AMK01_RS20680	COG2814	Major facilitator Superfamily
AMK01_RS20695	COG0488	(ABC) transporter
AMK01_RS20700	COG4178	(ABC) transporter
AMK01_RS20705	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AMK01_RS20715	COG2188	Transcriptional regulator
AMK01_RS20720	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AMK01_RS20725	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AMK01_RS20730	COG4821	SIS domain
AMK01_RS20740	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AMK01_RS20750	COG1509	lysine 2,3-aminomutase activity
AMK01_RS20755	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AMK01_RS20765	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AMK01_RS20780	COG0438	transferase activity, transferring glycosyl groups
AMK01_RS20805	COG5383	Protein conserved in bacteria
AMK01_RS20810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AMK01_RS20815	COG1012	belongs to the aldehyde dehydrogenase family
AMK01_RS20830	COG3842	ATPase activity
AMK01_RS20855	COG0477	Major facilitator Superfamily
AMK01_RS20860	COG0583	DNA-binding transcription factor activity
AMK01_RS20870	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AMK01_RS20875	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AMK01_RS20895	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AMK01_RS20900	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AMK01_RS20905	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AMK01_RS20910	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AMK01_RS20915	COG0725	ABC transporter, periplasmic molybdate-binding protein
AMK01_RS20920	COG4149	molybdate abc transporter
AMK01_RS20925	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AMK01_RS20935	COG0799	negative regulation of ribosome biogenesis
AMK01_RS20940	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AMK01_RS20950	COG0793	Belongs to the peptidase S41A family
AMK01_RS20960	COG0494	nUDIX hydrolase
AMK01_RS20975	COG0587	DNA-directed DNA polymerase activity
AMK01_RS21015	COG0066	3-isopropylmalate dehydratase activity
AMK01_RS21025	COG0473	3-isopropylmalate dehydrogenase activity
AMK01_RS21030	COG0671	phosphoesterase, PA-phosphatase related
AMK01_RS21045	COG1136	(ABC) transporter
AMK01_RS21055	COG1785	Belongs to the alkaline phosphatase family
AMK01_RS21065	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AMK01_RS21080	COG0288	reversible hydration of carbon dioxide
AMK01_RS21095	COG2902	Dehydrogenase
AMK01_RS21100	COG2270	Major facilitator Superfamily
AMK01_RS21105	COG0138	bifunctional purine biosynthesis protein purh
AMK01_RS21115	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AMK01_RS21115	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AMK01_RS21120	COG0501	Belongs to the peptidase M48B family
AMK01_RS21130	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AMK01_RS21150	COG0495	leucyl-tRNA aminoacylation
AMK01_RS21175	COG0357	Ribosomal RNA small subunit methyltransferase G
AMK01_RS21180	COG0445	tRNA wobble uridine modification
AMK01_RS21185	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AMK01_RS21190	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AMK01_RS21195	COG1981	membrane
AMK01_RS21400	COG0642	Histidine kinase
AMK01_RS21855	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AMK01_RS21950	COG2258	MOSC domain
AMK01_RS22410	COG0747	negative chemotaxis
AMK01_RS22465	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AMK01_RS22560	COG0318	PFAM AMP-dependent synthetase and ligase
AMK01_RS22795	COG1074	ATP-dependent DNA helicase activity
AMK01_RS22820	COG2205	protein histidine kinase activity
AMK01_RS22845	COG2205	protein histidine kinase activity
AMK01_RS22940	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AMK01_RS24015	COG0072	phenylalanine-tRNA ligase activity
AMK01_RS24015	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMK01_RS24375	COG2807	transmembrane transport
AMK01_RS24410	COG2814	Major facilitator Superfamily
AMK01_RS24480	COG1024	Enoyl-CoA hydratase
AMK01_RS24575	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AMK01_RS24655	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AMK01_RS24820	COG0642	Histidine kinase
AMK01_RS24975	COG1215	transferase activity, transferring glycosyl groups
AMK01_RS24995	COG2182	Extracellular solute-binding protein
AMK01_RS25115	COG1904	glucuronate isomerase
AMK01_RS25340	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AMK01_RS25480	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AMK01_RS25540	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AMK01_RS25545	COG3454	Phosphonate metabolism
AMK01_RS25595	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AMK01_RS25605	COG1132	(ABC) transporter
AMK01_RS25895	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AMK01_RS26065	COG0667	Aldo Keto reductase
AMK01_RS26120	COG1570	exodeoxyribonuclease VII activity
AMK01_RS26275	COG1968	undecaprenyl-diphosphatase activity
AMK01_RS26730	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AMK01_RS26790	COG0840	transmembrane signaling receptor activity
AMK01_RS27190	COG2205	protein histidine kinase activity
AMK01_RS27290	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AMK01_RS27490	COG0673	inositol 2-dehydrogenase activity
AMK01_RS27740	COG0582	viral genome integration into host DNA
AMK01_RS28345	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AMK01_RS28365	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AMK01_RS28425	COG0318	PFAM AMP-dependent synthetase and ligase
AMK01_RS29060	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AMK01_RS29075	COG0280	phosphate acetyltransferase
AMK01_RS29075	COG0281	malic enzyme
AMK01_RS29130	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AMK01_RS29515	COG3142	Participates in the control of copper homeostasis
AMK01_RS29635	COG2205	protein histidine kinase activity
AMK01_RS29700	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMK01_RS29840	COG1960	acyl-CoA dehydrogenase activity
AMK01_RS29920	COG0210	DNA helicase
AMK01_RS30135	COG4251	negative regulation of phosphorylation
AMK01_RS30275	COG1157	protein secretion by the type III secretion system