locus-tag	class	description
CMV14_RS00015	COG0483	inositol monophosphate 1-phosphatase activity
CMV14_RS00065	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CMV14_RS00070	COG1902	pentaerythritol trinitrate reductase activity
CMV14_RS00095	COG0629	single-stranded DNA binding
CMV14_RS00115	COG4974	Belongs to the 'phage' integrase family
CMV14_RS00120	COG2226	methyltransferase
CMV14_RS00130	COG0539	negative regulation of cytoplasmic translation
CMV14_RS00135	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CMV14_RS00140	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CMV14_RS00175	COG0784	Response regulator, receiver
CMV14_RS00185	COG1760	l-serine dehydratase
CMV14_RS00210	COG4771	TonB-dependent receptor
CMV14_RS00220	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CMV14_RS00265	COG1228	amidohydrolase
CMV14_RS00270	COG0488	(ABC) transporter
CMV14_RS00275	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CMV14_RS00280	COG0318	PFAM AMP-dependent synthetase and ligase
CMV14_RS00285	COG2244	polysaccharide biosynthetic process
CMV14_RS00310	COG2030	dehydratase
CMV14_RS00330	COG1024	Enoyl-CoA hydratase
CMV14_RS00340	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CMV14_RS00340	COG0674	pyruvate-flavodoxin oxidoreductase activity
CMV14_RS00365	COG1764	response to oxidative stress
CMV14_RS00375	COG1566	PFAM secretion protein HlyD family protein
CMV14_RS00380	COG2814	Major facilitator Superfamily
CMV14_RS00395	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CMV14_RS00400	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
CMV14_RS00410	COG4774	siderophore transport
CMV14_RS00430	COG0134	indole-3-glycerol-phosphate synthase activity
CMV14_RS00435	COG0315	cyclic pyranopterin monophosphate synthase activity
CMV14_RS00440	COG0303	'Molybdopterin
CMV14_RS00445	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CMV14_RS00450	COG0658	competence protein
CMV14_RS00450	COG2333	competence protein COMEC
CMV14_RS00455	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CMV14_RS00475	COG2205	protein histidine kinase activity
CMV14_RS00475	COG2202	Pas domain
CMV14_RS00500	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CMV14_RS00530	COG4115	mRNA cleavage
CMV14_RS00550	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CMV14_RS00575	COG0045	succinate-CoA ligase (ADP-forming) activity
CMV14_RS00580	COG2086	electron transfer activity
CMV14_RS00600	COG1573	uracil-dna glycosylase
CMV14_RS00645	COG0745	RESPONSE REGULATOR receiver
CMV14_RS00660	COG0438	transferase activity, transferring glycosyl groups
CMV14_RS00665	COG0673	inositol 2-dehydrogenase activity
CMV14_RS00690	COG2003	Belongs to the UPF0758 family
CMV14_RS00710	COG0481	GTPase activity
CMV14_RS00740	COG0625	glutathione transferase activity
CMV14_RS00745	COG0174	glutamine synthetase
CMV14_RS00750	COG0069	glutamate synthase activity
CMV14_RS00755	COG2218	PFAM glutamate synthase alpha subunit domain protein
CMV14_RS00760	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CMV14_RS00775	COG0446	pyridine nucleotide-disulphide oxidoreductase
CMV14_RS00775	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CMV14_RS00785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CMV14_RS00795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CMV14_RS00800	COG5425	PFAM Usg family protein
CMV14_RS00805	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CMV14_RS00810	COG0459	protein refolding
CMV14_RS00835	COG0205	6-phosphofructokinase activity
CMV14_RS00845	COG2884	Cell division ATP-binding protein ftsE
CMV14_RS00860	COG0204	Acyl-transferase
CMV14_RS00870	COG0287	Prephenate dehydrogenase
CMV14_RS00875	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CMV14_RS00880	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CMV14_RS00885	COG2813	Specifically methylates the guanine in position
CMV14_RS00885	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CMV14_RS00905	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CMV14_RS00915	COG1007	ATP synthesis coupled electron transport
CMV14_RS00930	COG0713	ATP synthesis coupled electron transport
CMV14_RS00940	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CMV14_RS00945	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CMV14_RS00950	COG1034	ATP synthesis coupled electron transport
CMV14_RS00960	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CMV14_RS00975	COG0649	NAD binding
CMV14_RS00980	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CMV14_RS00985	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CMV14_RS00990	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CMV14_RS00995	COG0483	inositol monophosphate 1-phosphatase activity
CMV14_RS01000	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CMV14_RS01005	COG1297	OPT oligopeptide transporter protein
CMV14_RS01025	COG4566	intracellular signal transduction
CMV14_RS01030	COG4191	Histidine kinase
CMV14_RS01040	COG3279	Response regulator of the LytR AlgR family
CMV14_RS01045	COG3275	phosphorelay sensor kinase activity
CMV14_RS01050	COG1301	dicarboxylic acid transport
CMV14_RS01065	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CMV14_RS01070	COG0363	glucosamine-6-phosphate deaminase activity
CMV14_RS01075	COG0129	dihydroxy-acid dehydratase activity
CMV14_RS01080	COG0837	glucose binding
CMV14_RS01085	COG0800	Aldolase
CMV14_RS01100	COG4770	biotin carboxylase activity
CMV14_RS01105	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CMV14_RS01110	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CMV14_RS01110	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CMV14_RS01115	COG0346	lactoylglutathione lyase activity
CMV14_RS01120	COG0183	Belongs to the thiolase family
CMV14_RS01125	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CMV14_RS01130	COG3800	Transcriptional regulator
CMV14_RS01130	COG1396	sequence-specific DNA binding
CMV14_RS01135	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CMV14_RS01140	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CMV14_RS01165	COG0071	Belongs to the small heat shock protein (HSP20) family
CMV14_RS01190	COG0583	DNA-binding transcription factor activity
CMV14_RS01200	COG0655	NAD(P)H dehydrogenase (quinone) activity
CMV14_RS01230	COG1671	Belongs to the UPF0178 family
CMV14_RS01240	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CMV14_RS01275	COG2814	Major facilitator Superfamily
CMV14_RS01290	COG5002	protein histidine kinase activity
CMV14_RS01305	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CMV14_RS01330	COG0546	phosphoglycolate phosphatase activity
CMV14_RS01335	COG0564	pseudouridine synthase activity
CMV14_RS01340	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CMV14_RS01360	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CMV14_RS01365	COG0135	phosphoribosylanthranilate isomerase activity
CMV14_RS01370	COG0133	tryptophan synthase activity
CMV14_RS01375	COG0159	tryptophan synthase activity
CMV14_RS01380	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CMV14_RS01390	COG0114	fumarate hydratase activity
CMV14_RS01405	COG0194	GDP metabolic process
CMV14_RS01415	COG0131	Imidazoleglycerol-phosphate dehydratase
CMV14_RS01420	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CMV14_RS01425	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CMV14_RS01430	COG0107	imidazoleglycerol-phosphate synthase activity
CMV14_RS01440	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CMV14_RS01450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CMV14_RS01465	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CMV14_RS01470	COG0281	malic enzyme
CMV14_RS01470	COG0280	phosphate acetyltransferase
CMV14_RS01490	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CMV14_RS01515	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CMV14_RS01520	COG1127	ABC transporter
CMV14_RS01540	COG0308	aminopeptidase N
CMV14_RS01580	COG2319	Wd-40 repeat
CMV14_RS01585	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CMV14_RS01590	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CMV14_RS01600	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CMV14_RS01605	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CMV14_RS01610	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CMV14_RS01615	COG2119	membrane
CMV14_RS01620	COG0783	Belongs to the Dps family
CMV14_RS01625	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CMV14_RS01670	COG2983	Belongs to the UPF0260 family
CMV14_RS01675	COG1999	signal sequence binding
CMV14_RS01710	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CMV14_RS01715	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CMV14_RS01720	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CMV14_RS01725	COG0237	dephospho-CoA kinase activity
CMV14_RS01730	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CMV14_RS01735	COG0424	maF-like protein
CMV14_RS01740	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CMV14_RS01745	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CMV14_RS01750	COG1981	membrane
CMV14_RS01755	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CMV14_RS01760	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CMV14_RS01780	COG0861	Integral membrane protein TerC family
CMV14_RS01810	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CMV14_RS01815	COG0445	tRNA wobble uridine modification
CMV14_RS01820	COG0357	Ribosomal RNA small subunit methyltransferase G
CMV14_RS01845	COG0495	leucyl-tRNA aminoacylation
CMV14_RS01875	COG1648	precorrin-2 dehydrogenase activity
CMV14_RS01875	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CMV14_RS01880	COG0667	Aldo Keto reductase
CMV14_RS01885	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CMV14_RS01890	COG0019	diaminopimelate decarboxylase activity
CMV14_RS01900	COG0165	Argininosuccinate lyase
CMV14_RS01905	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CMV14_RS01915	COG3384	dioxygenase
CMV14_RS01935	COG1872	DUF167
CMV14_RS01940	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CMV14_RS01945	COG2095	MarC family integral membrane protein
CMV14_RS01960	COG2246	polysaccharide biosynthetic process
CMV14_RS01965	COG0463	Glycosyl transferase, family 2
CMV14_RS01970	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CMV14_RS01985	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
CMV14_RS02000	COG0137	argininosuccinate synthase activity
CMV14_RS02025	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS02030	COG2066	Belongs to the glutaminase family
CMV14_RS02050	COG1201	RNA secondary structure unwinding
CMV14_RS02065	COG1192	Involved in chromosome partitioning
CMV14_RS02070	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CMV14_RS02080	COG1250	3-hydroxyacyl-CoA dehydrogenase
CMV14_RS02085	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CMV14_RS02090	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CMV14_RS02095	COG1278	Cold shock
CMV14_RS02100	COG1253	flavin adenine dinucleotide binding
CMV14_RS02120	COG1592	Rubrerythrin
CMV14_RS02125	COG0247	lactate metabolic process
CMV14_RS02150	COG1846	Transcriptional regulator
CMV14_RS02155	COG1764	response to oxidative stress
CMV14_RS02165	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CMV14_RS02170	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CMV14_RS02180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CMV14_RS02200	COG0501	Belongs to the peptidase M48B family
CMV14_RS02205	COG4269	membrane
CMV14_RS02210	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CMV14_RS02225	COG2171	N-acyltransferase activity
CMV14_RS02235	COG1278	Cold shock
CMV14_RS02240	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CMV14_RS02250	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CMV14_RS02260	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CMV14_RS02275	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CMV14_RS02285	COG2917	probably involved in intracellular septation
CMV14_RS02290	COG0552	protein localization to endoplasmic reticulum
CMV14_RS02295	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CMV14_RS02300	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CMV14_RS02305	COG5001	Diguanylate cyclase
CMV14_RS02305	COG3300	MHYT domain
CMV14_RS02315	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CMV14_RS02320	COG1842	Phage shock protein A
CMV14_RS02365	COG1137	ATPase activity
CMV14_RS02370	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CMV14_RS02375	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CMV14_RS02380	COG0228	four-way junction DNA binding
CMV14_RS02385	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CMV14_RS02410	COG0336	Belongs to the RNA methyltransferase TrmD family
CMV14_RS02415	COG0335	large ribosomal subunit rRNA binding
CMV14_RS02420	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CMV14_RS02430	COG0596	Alpha beta hydrolase
CMV14_RS02440	COG2199	diguanylate cyclase activity
CMV14_RS02445	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CMV14_RS02450	COG0678	peroxiredoxin activity
CMV14_RS02455	COG1216	Glycosyl transferase, family 2
CMV14_RS02455	COG0438	transferase activity, transferring glycosyl groups
CMV14_RS02460	COG1678	Uncharacterized ACR, COG1678
CMV14_RS02470	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CMV14_RS02480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CMV14_RS02485	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CMV14_RS02495	COG2205	protein histidine kinase activity
CMV14_RS02500	COG0802	atpase or kinase
CMV14_RS02505	COG3178	'Phosphotransferase
CMV14_RS02510	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CMV14_RS02520	COG1074	ATP-dependent DNA helicase activity
CMV14_RS02535	COG0625	glutathione transferase activity
CMV14_RS02540	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CMV14_RS02545	COG0653	protein targeting
CMV14_RS02550	COG2832	Protein of unknown function (DUF454)
CMV14_RS02560	COG1160	GTP binding
CMV14_RS02565	COG0425	Belongs to the sulfur carrier protein TusA family
CMV14_RS02585	COG4106	trans-aconitate 2-methyltransferase activity
CMV14_RS02585	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CMV14_RS02595	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CMV14_RS02605	COG0588	phosphoglycerate mutase activity
CMV14_RS02610	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CMV14_RS02615	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CMV14_RS02630	COG0612	Peptidase, M16
CMV14_RS02635	COG0542	response to heat
CMV14_RS02670	COG0457	Tetratricopeptide repeat
CMV14_RS02675	COG4771	TonB-dependent receptor
CMV14_RS02695	COG1570	exodeoxyribonuclease VII activity
CMV14_RS02700	COG0151	Belongs to the GarS family
CMV14_RS02710	COG0352	thiamine-phosphate diphosphorylase activity
CMV14_RS02715	COG3588	fructose-bisphosphate aldolase
CMV14_RS02730	COG0126	phosphoglycerate kinase activity
CMV14_RS02740	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CMV14_RS02790	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CMV14_RS02860	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CMV14_RS02870	COG0484	heat shock protein binding
CMV14_RS02875	COG4191	Histidine kinase
CMV14_RS02875	COG0784	Response regulator, receiver
CMV14_RS02890	COG2166	iron-sulfur cluster assembly
CMV14_RS02895	COG1022	Amp-dependent synthetase and ligase
CMV14_RS02900	COG0405	Gamma-glutamyltransferase
CMV14_RS02905	COG0167	dihydroorotate dehydrogenase activity
CMV14_RS02915	COG0719	Fe-S assembly protein
CMV14_RS02925	COG2852	Protein conserved in bacteria
CMV14_RS02930	COG0396	ATPase activity
CMV14_RS02935	COG0719	Fe-S assembly protein
CMV14_RS02945	COG2151	metal-sulfur cluster biosynthetic enzyme
CMV14_RS02950	COG0316	Belongs to the HesB IscA family
CMV14_RS02955	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CMV14_RS02990	COG0166	Belongs to the GPI family
CMV14_RS03000	COG1187	pseudouridine synthase activity
CMV14_RS03005	COG0742	ribosomal rna small subunit methyltransferase
CMV14_RS03030	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CMV14_RS03035	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CMV14_RS03040	COG0509	glycine decarboxylation via glycine cleavage system
CMV14_RS03045	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CMV14_RS03055	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CMV14_RS03060	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CMV14_RS03065	COG0328	RNA-DNA hybrid ribonuclease activity
CMV14_RS03070	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CMV14_RS03080	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CMV14_RS03085	COG3750	Belongs to the UPF0335 family
CMV14_RS03090	COG0469	pyruvate kinase activity
CMV14_RS03095	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CMV14_RS03105	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CMV14_RS03115	COG2866	Carboxypeptidase
CMV14_RS03120	COG4206	TonB-dependent receptor
CMV14_RS03145	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CMV14_RS03150	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CMV14_RS03150	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CMV14_RS03210	COG1459	type II secretion system
CMV14_RS03265	COG0531	amino acid
CMV14_RS03275	COG0140	phosphoribosyl-ATP diphosphatase activity
CMV14_RS03285	COG0081	regulation of translation
CMV14_RS03290	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CMV14_RS03295	COG0250	Participates in transcription elongation, termination and antitermination
CMV14_RS03315	COG0318	PFAM AMP-dependent synthetase and ligase
CMV14_RS03325	COG1278	Cold shock
CMV14_RS03350	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CMV14_RS03365	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
CMV14_RS03375	COG0793	Belongs to the peptidase S41A family
CMV14_RS03385	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CMV14_RS03390	COG0799	negative regulation of ribosome biogenesis
CMV14_RS03395	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CMV14_RS03425	COG2814	Major facilitator Superfamily
CMV14_RS03430	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CMV14_RS03435	COG0124	histidyl-tRNA synthetase
CMV14_RS03440	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CMV14_RS03445	COG2890	protein-(glutamine-N5) methyltransferase activity
CMV14_RS03460	COG0517	IMP dehydrogenase activity
CMV14_RS03495	COG4771	TonB-dependent receptor
CMV14_RS03500	COG1309	transcriptional regulator
CMV14_RS03515	COG2130	NADP-dependent
CMV14_RS03525	COG0583	DNA-binding transcription factor activity
CMV14_RS03555	COG0438	transferase activity, transferring glycosyl groups
CMV14_RS03600	COG0459	protein refolding
CMV14_RS03605	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CMV14_RS03610	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CMV14_RS03615	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CMV14_RS03620	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CMV14_RS03625	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CMV14_RS03635	COG4771	TonB-dependent receptor
CMV14_RS03640	COG2819	hydrolase of the alpha beta superfamily
CMV14_RS03685	COG1228	amidohydrolase
CMV14_RS03690	COG0402	S-adenosylhomocysteine deaminase activity
CMV14_RS03715	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CMV14_RS03720	COG0583	DNA-binding transcription factor activity
CMV14_RS03730	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CMV14_RS03740	COG0183	Belongs to the thiolase family
CMV14_RS03745	COG1414	Transcriptional regulator
CMV14_RS03765	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CMV14_RS03770	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CMV14_RS03775	COG0435	Glutathione S-transferase
CMV14_RS03780	COG0625	glutathione transferase activity
CMV14_RS03785	COG4771	TonB-dependent receptor
CMV14_RS03805	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CMV14_RS03820	COG4774	siderophore transport
CMV14_RS03830	COG0583	DNA-binding transcription factor activity
CMV14_RS03835	COG0625	glutathione transferase activity
CMV14_RS03840	COG1454	alcohol dehydrogenase
CMV14_RS03855	COG0183	Belongs to the thiolase family
CMV14_RS03860	COG3246	L-lysine catabolic process to acetate
CMV14_RS03880	COG1960	acyl-CoA dehydrogenase activity
CMV14_RS03900	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CMV14_RS03905	COG0633	Ferredoxin
CMV14_RS03925	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS03940	COG1960	acyl-CoA dehydrogenase activity
CMV14_RS03950	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CMV14_RS03965	COG4771	TonB-dependent receptor
CMV14_RS03975	COG1012	belongs to the aldehyde dehydrogenase family
CMV14_RS03995	COG0596	Alpha beta hydrolase
CMV14_RS04000	COG0596	Alpha beta hydrolase
CMV14_RS04005	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CMV14_RS04010	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CMV14_RS04020	COG0667	Aldo Keto reductase
CMV14_RS04025	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CMV14_RS04030	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CMV14_RS04040	COG1309	transcriptional regulator
CMV14_RS04045	COG1960	acyl-CoA dehydrogenase activity
CMV14_RS04050	COG0318	PFAM AMP-dependent synthetase and ligase
CMV14_RS04060	COG2814	Major facilitator Superfamily
CMV14_RS04070	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
CMV14_RS04075	COG1960	acyl-CoA dehydrogenase activity
CMV14_RS04080	COG0583	DNA-binding transcription factor activity
CMV14_RS04095	COG2205	protein histidine kinase activity
CMV14_RS04105	COG0659	secondary active sulfate transmembrane transporter activity
CMV14_RS04115	COG3746	phosphate-selective porin O and P
CMV14_RS04125	COG5002	protein histidine kinase activity
CMV14_RS04130	COG0745	RESPONSE REGULATOR receiver
CMV14_RS04170	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CMV14_RS04175	COG1960	acyl-CoA dehydrogenase activity
CMV14_RS04180	COG0583	DNA-binding transcription factor activity
CMV14_RS04185	COG5507	3-demethylubiquinone-9 3-methyltransferase
CMV14_RS04205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CMV14_RS04215	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CMV14_RS04245	COG1136	(ABC) transporter
CMV14_RS04245	COG0577	efflux transmembrane transporter activity
CMV14_RS04250	COG0577	efflux transmembrane transporter activity
CMV14_RS04250	COG1136	(ABC) transporter
CMV14_RS04265	COG2205	protein histidine kinase activity
CMV14_RS04275	COG0022	dehydrogenase e1 component
CMV14_RS04285	COG0217	transcriptional regulatory protein
CMV14_RS04300	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CMV14_RS04305	COG0632	four-way junction helicase activity
CMV14_RS04310	COG2255	four-way junction helicase activity
CMV14_RS04315	COG0824	Thioesterase
CMV14_RS04320	COG0811	peptide transport
CMV14_RS04335	COG0823	Involved in the tonB-independent uptake of proteins
CMV14_RS04340	COG2885	chlorophyll binding
CMV14_RS04355	COG1446	asparaginase
CMV14_RS04360	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CMV14_RS04365	COG0697	spore germination
CMV14_RS04370	COG0456	acetyltransferase
CMV14_RS04380	COG2076	Multidrug Resistance protein
CMV14_RS04435	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CMV14_RS04445	COG0628	permease
CMV14_RS04455	COG5001	Diguanylate cyclase
CMV14_RS04485	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CMV14_RS04490	COG0085	RNA polymerase activity
CMV14_RS04505	COG4771	TonB-dependent receptor
CMV14_RS04530	COG4771	TonB-dependent receptor
CMV14_RS04535	COG0222	ribosome binding
CMV14_RS04540	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CMV14_RS04545	COG3038	cytochrome b561
CMV14_RS04550	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CMV14_RS04555	COG0488	(ABC) transporter
CMV14_RS04580	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CMV14_RS04590	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CMV14_RS04645	COG0183	Belongs to the thiolase family
CMV14_RS04650	COG0583	DNA-binding transcription factor activity
CMV14_RS04655	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CMV14_RS04665	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CMV14_RS04675	COG1758	RNA polymerase activity
CMV14_RS04685	COG0583	DNA-binding transcription factor activity
CMV14_RS04690	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CMV14_RS04695	COG0450	alkyl hydroperoxide reductase
CMV14_RS04700	COG0583	DNA-binding transcription factor activity
CMV14_RS04715	COG1595	DNA-templated transcription, initiation
CMV14_RS04720	COG0314	molybdopterin synthase activity
CMV14_RS04730	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CMV14_RS04750	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CMV14_RS04765	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CMV14_RS04770	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CMV14_RS04770	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CMV14_RS04775	COG0501	Belongs to the peptidase M48B family
CMV14_RS04795	COG0181	hydroxymethylbilane synthase activity
CMV14_RS04800	COG0534	Mate efflux family protein
CMV14_RS04810	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CMV14_RS04815	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CMV14_RS04835	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CMV14_RS04850	COG1131	(ABC) transporter
CMV14_RS04880	COG0312	modulator of DNA gyrase
CMV14_RS04895	COG0347	Belongs to the P(II) protein family
CMV14_RS04900	COG0004	ammonium transporteR
CMV14_RS04915	COG0514	ATP-dependent DNA helicase (RecQ)
CMV14_RS04925	COG5265	(ABC) transporter
CMV14_RS04940	COG4957	zinc ion binding
CMV14_RS04950	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CMV14_RS04955	COG4569	acetaldehyde dehydrogenase (acetylating) activity
CMV14_RS04960	COG1414	Transcriptional regulator
CMV14_RS04965	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CMV14_RS04970	COG0572	uridine kinase
CMV14_RS04985	COG1960	acyl-CoA dehydrogenase activity
CMV14_RS04990	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CMV14_RS04995	COG0028	Belongs to the TPP enzyme family
CMV14_RS05015	COG0318	PFAM AMP-dependent synthetase and ligase
CMV14_RS05020	COG1960	acyl-CoA dehydrogenase activity
CMV14_RS05045	COG1309	transcriptional regulator
CMV14_RS05050	COG4771	TonB-dependent receptor
CMV14_RS05085	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CMV14_RS05090	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CMV14_RS05110	COG2010	Cytochrome c
CMV14_RS05140	COG0179	Fumarylacetoacetate (FAA) hydrolase
CMV14_RS05145	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CMV14_RS05160	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS05210	COG3047	cAMP biosynthetic process
CMV14_RS05215	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CMV14_RS05220	COG2346	COG2346, Truncated hemoglobins
CMV14_RS05255	COG4191	Histidine kinase
CMV14_RS05285	COG0045	succinate-CoA ligase (ADP-forming) activity
CMV14_RS05285	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CMV14_RS05285	COG1042	CoA-binding domain protein
CMV14_RS05310	COG0071	Belongs to the small heat shock protein (HSP20) family
CMV14_RS05325	COG1136	(ABC) transporter
CMV14_RS05350	COG1063	alcohol dehydrogenase
CMV14_RS05380	COG0446	pyridine nucleotide-disulphide oxidoreductase
CMV14_RS05405	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CMV14_RS05410	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CMV14_RS05415	COG5001	Diguanylate cyclase
CMV14_RS05420	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CMV14_RS05430	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CMV14_RS05440	COG3655	Transcriptional regulator
CMV14_RS05465	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS05475	COG4771	TonB-dependent receptor
CMV14_RS05490	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS05525	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CMV14_RS05550	COG1960	acyl-CoA dehydrogenase activity
CMV14_RS05555	COG1960	acyl-CoA dehydrogenase activity
CMV14_RS05565	COG1250	3-hydroxyacyl-CoA dehydrogenase
CMV14_RS05570	COG1024	Enoyl-CoA hydratase
CMV14_RS05590	COG1053	succinate dehydrogenase
CMV14_RS05605	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS05615	COG4771	TonB-dependent receptor
CMV14_RS05620	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS05630	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS05635	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS05645	COG4638	Rieske (2fe-2S)
CMV14_RS05650	COG0300	oxidoreductase activity
CMV14_RS05665	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS05685	COG0183	Belongs to the thiolase family
CMV14_RS05695	COG1024	Enoyl-CoA hydratase
CMV14_RS05700	COG0183	Belongs to the thiolase family
CMV14_RS05705	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CMV14_RS05710	COG0022	dehydrogenase e1 component
CMV14_RS05715	COG0022	dehydrogenase e1 component
CMV14_RS05715	COG0508	dehydrogenase complex catalyzes the overall conversion of
CMV14_RS05730	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS05740	COG0583	DNA-binding transcription factor activity
CMV14_RS05760	COG0596	Alpha beta hydrolase
CMV14_RS05770	COG2124	cytochrome p450
CMV14_RS05780	COG2124	cytochrome p450
CMV14_RS05785	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS05790	COG2124	cytochrome p450
CMV14_RS05800	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CMV14_RS05805	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CMV14_RS05860	COG1218	3'(2'),5'-bisphosphate nucleotidase
CMV14_RS05870	COG0175	sulfate reduction
CMV14_RS05885	COG1960	acyl-CoA dehydrogenase activity
CMV14_RS05890	COG1960	acyl-CoA dehydrogenase activity
CMV14_RS05905	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS05930	COG1024	Enoyl-CoA hydratase
CMV14_RS05945	COG1024	Enoyl-CoA hydratase
CMV14_RS05955	COG0183	Belongs to the thiolase family
CMV14_RS05960	COG1960	acyl-CoA dehydrogenase activity
CMV14_RS05965	COG1309	transcriptional regulator
CMV14_RS05970	COG0306	phosphate transporter
CMV14_RS05975	COG1392	Phosphate transport regulator
CMV14_RS05995	COG3387	PFAM Glycoside hydrolase 15-related
CMV14_RS06000	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CMV14_RS06015	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CMV14_RS06120	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CMV14_RS06125	COG0594	ribonuclease P activity
CMV14_RS06130	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CMV14_RS06135	COG0706	membrane insertase activity
CMV14_RS06140	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CMV14_RS06155	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CMV14_RS06200	COG0438	transferase activity, transferring glycosyl groups
CMV14_RS06210	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CMV14_RS06225	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
CMV14_RS06260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CMV14_RS06305	COG4584	PFAM Integrase catalytic
CMV14_RS06320	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CMV14_RS06330	COG0579	oxidoreductase
CMV14_RS06340	COG0492	ferredoxin-NADP+ reductase activity
CMV14_RS06350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CMV14_RS06355	COG0019	diaminopimelate decarboxylase activity
CMV14_RS06380	COG3267	Type II secretory pathway component ExeA
CMV14_RS06380	COG3409	Peptidoglycan-binding domain 1 protein
CMV14_RS06400	COG0367	asparagine synthase
CMV14_RS06410	COG0101	tRNA pseudouridine synthase activity
CMV14_RS06415	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CMV14_RS06420	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CMV14_RS06430	COG0242	peptide deformylase activity
CMV14_RS06440	COG3128	pkhd-type hydroxylase
CMV14_RS06450	COG0557	exoribonuclease II activity
CMV14_RS06460	COG0717	Belongs to the dCTP deaminase family
CMV14_RS06465	COG0295	cytidine deaminase activity
CMV14_RS06470	COG5328	Belongs to the UPF0262 family
CMV14_RS06475	COG1566	PFAM secretion protein HlyD family protein
CMV14_RS06485	COG0305	Participates in initiation and elongation during chromosome replication
CMV14_RS06490	COG0175	sulfate reduction
CMV14_RS06510	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CMV14_RS06510	COG1648	precorrin-2 dehydrogenase activity
CMV14_RS06540	COG0583	DNA-binding transcription factor activity
CMV14_RS06555	COG0386	Belongs to the glutathione peroxidase family
CMV14_RS06560	COG1846	Transcriptional regulator
CMV14_RS06565	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CMV14_RS06575	COG0730	response to heat
CMV14_RS06580	COG4774	siderophore transport
CMV14_RS06580	COG1629	transport
CMV14_RS06595	COG0284	orotidine-5'-phosphate decarboxylase activity
CMV14_RS06610	COG1752	Esterase of the alpha-beta hydrolase superfamily
CMV14_RS06640	COG0521	Mo-molybdopterin cofactor biosynthetic process
CMV14_RS06645	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CMV14_RS06685	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CMV14_RS06705	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CMV14_RS06710	COG0424	maF-like protein
CMV14_RS06720	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CMV14_RS06775	COG0445	tRNA wobble uridine modification
CMV14_RS06780	COG2814	Major facilitator Superfamily
CMV14_RS06785	COG4206	TonB-dependent receptor
CMV14_RS06790	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS06800	COG3321	synthase
CMV14_RS06800	COG0604	alcohol dehydrogenase
CMV14_RS06800	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS06805	COG1024	Enoyl-CoA hydratase
CMV14_RS06820	COG1846	Transcriptional regulator
CMV14_RS06850	COG0523	cobalamin synthesis protein
CMV14_RS06855	COG3618	amidohydrolase
CMV14_RS06865	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CMV14_RS06870	COG0583	DNA-binding transcription factor activity
CMV14_RS06880	COG2159	amidohydrolase
CMV14_RS06910	COG1999	signal sequence binding
CMV14_RS06925	COG0318	PFAM AMP-dependent synthetase and ligase
CMV14_RS06950	COG3384	dioxygenase
CMV14_RS06955	COG0251	oxidation-reduction process
CMV14_RS06960	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CMV14_RS06965	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CMV14_RS06965	COG0473	3-isopropylmalate dehydrogenase activity
CMV14_RS06985	COG4948	Mandelate Racemase Muconate Lactonizing
CMV14_RS06995	COG0445	tRNA wobble uridine modification
CMV14_RS07000	COG1012	belongs to the aldehyde dehydrogenase family
CMV14_RS07030	COG4771	TonB-dependent receptor
CMV14_RS07040	COG1024	Enoyl-CoA hydratase
CMV14_RS07045	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CMV14_RS07050	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CMV14_RS07055	COG3971	2-oxopent-4-enoate hydratase activity
CMV14_RS07075	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS07085	COG0179	Fumarylacetoacetate (FAA) hydrolase
CMV14_RS07100	COG4771	TonB-dependent receptor
CMV14_RS07105	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CMV14_RS07110	COG2814	Major facilitator Superfamily
CMV14_RS07115	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CMV14_RS07125	COG0657	acetylesterase activity
CMV14_RS07130	COG0318	PFAM AMP-dependent synthetase and ligase
CMV14_RS07140	COG0438	transferase activity, transferring glycosyl groups
CMV14_RS07155	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CMV14_RS07170	COG1024	Enoyl-CoA hydratase
CMV14_RS07190	COG1024	Enoyl-CoA hydratase
CMV14_RS07200	COG0583	DNA-binding transcription factor activity
CMV14_RS07205	COG0235	Class ii aldolase
CMV14_RS07210	COG2086	electron transfer activity
CMV14_RS07225	COG1024	Enoyl-CoA hydratase
CMV14_RS07230	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS07235	COG0183	Belongs to the thiolase family
CMV14_RS07255	COG1309	transcriptional regulator
CMV14_RS07270	COG1760	l-serine dehydratase
CMV14_RS07285	COG0446	pyridine nucleotide-disulphide oxidoreductase
CMV14_RS07285	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CMV14_RS07295	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CMV14_RS07305	COG1960	acyl-CoA dehydrogenase activity
CMV14_RS07310	COG1960	acyl-CoA dehydrogenase activity
CMV14_RS07315	COG0346	lactoylglutathione lyase activity
CMV14_RS07325	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS07375	COG4771	TonB-dependent receptor
CMV14_RS07380	COG1053	succinate dehydrogenase
CMV14_RS07385	COG4638	Rieske (2fe-2S)
CMV14_RS07400	COG1960	acyl-CoA dehydrogenase activity
CMV14_RS07435	COG2814	Major facilitator Superfamily
CMV14_RS07445	COG0508	dehydrogenase complex catalyzes the overall conversion of
CMV14_RS07445	COG0022	dehydrogenase e1 component
CMV14_RS07465	COG0667	Aldo Keto reductase
CMV14_RS07470	COG1053	succinate dehydrogenase
CMV14_RS07475	COG0022	dehydrogenase e1 component
CMV14_RS07480	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CMV14_RS07485	COG0318	PFAM AMP-dependent synthetase and ligase
CMV14_RS07490	COG4638	Rieske (2fe-2S)
CMV14_RS07495	COG2030	dehydratase
CMV14_RS07520	COG1960	acyl-CoA dehydrogenase activity
CMV14_RS07530	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CMV14_RS07550	COG0183	Belongs to the thiolase family
CMV14_RS07585	COG4771	TonB-dependent receptor
CMV14_RS07595	COG2124	cytochrome p450
CMV14_RS07605	COG1024	Enoyl-CoA hydratase
CMV14_RS07610	COG1024	Enoyl-CoA hydratase
CMV14_RS07620	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CMV14_RS07625	COG4133	protoheme IX ABC transporter activity
CMV14_RS07635	COG2154	pterin-4-alpha-carbinolamine dehydratase
CMV14_RS07705	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CMV14_RS07710	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CMV14_RS07715	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CMV14_RS07735	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CMV14_RS07740	COG0602	queuosine metabolic process
CMV14_RS07755	COG0321	lipoyl(octanoyl) transferase activity
CMV14_RS07770	COG0408	coproporphyrinogen oxidase activity
CMV14_RS07775	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CMV14_RS07795	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CMV14_RS07805	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CMV14_RS07810	COG0012	GTP binding
CMV14_RS07820	COG3647	Membrane
CMV14_RS07825	COG2205	protein histidine kinase activity
CMV14_RS07830	COG3437	response regulator, receiver
CMV14_RS07830	COG2205	protein histidine kinase activity
CMV14_RS07830	COG3850	Histidine kinase
CMV14_RS07830	COG4999	Histidine kinase
CMV14_RS07865	COG0193	aminoacyl-tRNA hydrolase activity
CMV14_RS07870	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CMV14_RS07875	COG0564	pseudouridine synthase activity
CMV14_RS07895	COG1956	GAF domain-containing protein
CMV14_RS07905	COG0508	dehydrogenase complex catalyzes the overall conversion of
CMV14_RS07910	COG1607	acyl-coa hydrolase
CMV14_RS07915	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CMV14_RS07925	COG1686	Belongs to the peptidase S11 family
CMV14_RS07935	COG2989	Protein conserved in bacteria
CMV14_RS07945	COG1324	tolerance protein
CMV14_RS07950	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CMV14_RS07955	COG0049	tRNA binding
CMV14_RS07960	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CMV14_RS07965	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CMV14_RS07970	COG0051	transcription antitermination factor activity, RNA binding
CMV14_RS07975	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CMV14_RS07980	COG0088	Forms part of the polypeptide exit tunnel
CMV14_RS07985	COG0089	rRNA binding
CMV14_RS07990	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CMV14_RS07995	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CMV14_RS08000	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CMV14_RS08005	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CMV14_RS08010	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CMV14_RS08015	COG0255	Belongs to the universal ribosomal protein uL29 family
CMV14_RS08020	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CMV14_RS08025	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CMV14_RS08030	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CMV14_RS08035	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CMV14_RS08040	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CMV14_RS08045	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CMV14_RS08050	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CMV14_RS08055	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CMV14_RS08060	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CMV14_RS08065	COG1841	ribosomal large subunit assembly
CMV14_RS08070	COG0200	Binds to the 23S rRNA
CMV14_RS08075	COG0201	protein transport
CMV14_RS08080	COG0563	adenylate kinase activity
CMV14_RS08090	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CMV14_RS08100	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CMV14_RS08105	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CMV14_RS08110	COG0202	RNA polymerase activity
CMV14_RS08115	COG0203	ribosomal protein L17
CMV14_RS08120	COG1505	serine-type exopeptidase activity
CMV14_RS08140	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CMV14_RS08140	COG0519	Catalyzes the synthesis of GMP from XMP
CMV14_RS08150	COG0183	Belongs to the thiolase family
CMV14_RS08160	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS08180	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CMV14_RS08230	COG1250	3-hydroxyacyl-CoA dehydrogenase
CMV14_RS08235	COG3321	synthase
CMV14_RS08235	COG0604	alcohol dehydrogenase
CMV14_RS08235	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS08240	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CMV14_RS08245	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CMV14_RS08255	COG2204	response regulator
CMV14_RS08280	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS08285	COG2207	Transcriptional regulator
CMV14_RS08285	COG0662	Cupin 2, conserved barrel domain protein
CMV14_RS08315	COG3706	GGDEF domain
CMV14_RS08325	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS08355	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CMV14_RS08375	COG1213	nucleotidyl transferase
CMV14_RS08400	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CMV14_RS08410	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CMV14_RS08420	COG4774	siderophore transport
CMV14_RS08430	COG0039	L-malate dehydrogenase activity
CMV14_RS08435	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CMV14_RS08445	COG0508	dehydrogenase complex catalyzes the overall conversion of
CMV14_RS08450	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CMV14_RS08460	COG0443	Heat shock 70 kDa protein
CMV14_RS08465	COG0436	Aminotransferase
CMV14_RS08495	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CMV14_RS08505	COG1677	Flagellar hook-basal body complex protein FliE
CMV14_RS08515	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CMV14_RS08520	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CMV14_RS08535	COG0489	protein tyrosine kinase activity
CMV14_RS08540	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CMV14_RS08610	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CMV14_RS08620	COG4787	bacterial-type flagellum-dependent cell motility
CMV14_RS08625	COG4786	Flagellar basal body rod
CMV14_RS08630	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CMV14_RS08635	COG1706	bacterial-type flagellum-dependent cell motility
CMV14_RS08650	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CMV14_RS08680	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CMV14_RS08685	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CMV14_RS08700	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CMV14_RS08720	COG0443	Heat shock 70 kDa protein
CMV14_RS08725	COG0484	heat shock protein binding
CMV14_RS08780	COG4452	Inner membrane protein CreD
CMV14_RS08800	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CMV14_RS08810	COG0438	transferase activity, transferring glycosyl groups
CMV14_RS08835	COG0505	Belongs to the CarA family
CMV14_RS08875	COG2204	response regulator
CMV14_RS08885	COG1136	(ABC) transporter
CMV14_RS08885	COG0577	efflux transmembrane transporter activity
CMV14_RS08890	COG0577	efflux transmembrane transporter activity
CMV14_RS08890	COG1136	(ABC) transporter
CMV14_RS08895	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CMV14_RS08920	COG0022	dehydrogenase e1 component
CMV14_RS08920	COG0508	dehydrogenase complex catalyzes the overall conversion of
CMV14_RS08925	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CMV14_RS08965	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CMV14_RS08980	COG0210	DNA helicase
CMV14_RS08985	COG2814	Major facilitator Superfamily
CMV14_RS09005	COG0784	Response regulator, receiver
CMV14_RS09010	COG1301	dicarboxylic acid transport
CMV14_RS09020	COG2957	Belongs to the agmatine deiminase family
CMV14_RS09075	COG0246	Mannitol dehydrogenase
CMV14_RS09080	COG1940	carbohydrate kinase activity
CMV14_RS09100	COG0277	FAD linked oxidase domain protein
CMV14_RS09110	COG2272	Belongs to the type-B carboxylesterase lipase family
CMV14_RS09120	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CMV14_RS09125	COG2814	Major facilitator Superfamily
CMV14_RS09140	COG1309	transcriptional regulator
CMV14_RS09145	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CMV14_RS09175	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CMV14_RS09180	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CMV14_RS09205	COG2169	Transcriptional regulator
CMV14_RS09205	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CMV14_RS09230	COG2354	Protein conserved in bacteria
CMV14_RS09235	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CMV14_RS09240	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CMV14_RS09265	COG3483	tryptophan 2,3-dioxygenase activity
CMV14_RS09280	COG0531	amino acid
CMV14_RS09300	COG2814	Major facilitator Superfamily
CMV14_RS09325	COG1024	Enoyl-CoA hydratase
CMV14_RS09330	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CMV14_RS09335	COG1960	acyl-CoA dehydrogenase activity
CMV14_RS09355	COG4771	TonB-dependent receptor
CMV14_RS09375	COG2124	cytochrome p450
CMV14_RS09380	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS09390	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS09445	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CMV14_RS09455	COG1596	polysaccharide export
CMV14_RS09475	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CMV14_RS09475	COG2755	lipolytic protein G-D-S-L family
CMV14_RS09490	COG1696	Membrane protein involved in D-alanine export
CMV14_RS09505	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CMV14_RS09505	COG1648	precorrin-2 dehydrogenase activity
CMV14_RS09510	COG0243	molybdopterin cofactor binding
CMV14_RS09515	COG2146	nitrite reductase [NAD(P)H] activity
CMV14_RS09520	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CMV14_RS09525	COG2223	nitrite transmembrane transporter activity
CMV14_RS09535	COG1116	anion transmembrane transporter activity
CMV14_RS09540	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CMV14_RS09545	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CMV14_RS09550	COG1116	anion transmembrane transporter activity
CMV14_RS09550	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CMV14_RS09560	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CMV14_RS09565	COG1595	DNA-templated transcription, initiation
CMV14_RS09575	COG1522	sequence-specific DNA binding
CMV14_RS09585	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CMV14_RS09595	COG0745	RESPONSE REGULATOR receiver
CMV14_RS09600	COG5002	protein histidine kinase activity
CMV14_RS09650	COG0308	aminopeptidase N
CMV14_RS09675	COG3321	synthase
CMV14_RS09675	COG0604	alcohol dehydrogenase
CMV14_RS09675	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS09680	COG1960	acyl-CoA dehydrogenase activity
CMV14_RS09695	COG1278	Cold shock
CMV14_RS09715	COG2130	NADP-dependent
CMV14_RS09720	COG1522	sequence-specific DNA binding
CMV14_RS09725	COG1448	Aminotransferase
CMV14_RS09745	COG0129	dihydroxy-acid dehydratase activity
CMV14_RS09755	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS09780	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CMV14_RS09785	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS09800	COG0604	alcohol dehydrogenase
CMV14_RS09810	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS09820	COG2814	Major facilitator Superfamily
CMV14_RS09825	COG2814	Major facilitator Superfamily
CMV14_RS09830	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CMV14_RS09835	COG0583	DNA-binding transcription factor activity
CMV14_RS09840	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CMV14_RS09845	COG4771	TonB-dependent receptor
CMV14_RS09850	COG2072	flavoprotein involved in K transport
CMV14_RS09880	COG0300	oxidoreductase activity
CMV14_RS09890	COG0179	Fumarylacetoacetate (FAA) hydrolase
CMV14_RS09905	COG3246	L-lysine catabolic process to acetate
CMV14_RS09925	COG1522	sequence-specific DNA binding
CMV14_RS09930	COG3246	L-lysine catabolic process to acetate
CMV14_RS09945	COG1414	Transcriptional regulator
CMV14_RS09975	COG3971	2-oxopent-4-enoate hydratase activity
CMV14_RS09995	COG3273	potassium ion transport
CMV14_RS09995	COG0471	metal ion transport
CMV14_RS10005	COG4771	TonB-dependent receptor
CMV14_RS10010	COG1024	Enoyl-CoA hydratase
CMV14_RS10020	COG2814	Major facilitator Superfamily
CMV14_RS10030	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS10040	COG0183	Belongs to the thiolase family
CMV14_RS10045	COG1414	Transcriptional regulator
CMV14_RS10050	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CMV14_RS10055	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CMV14_RS10060	COG0583	DNA-binding transcription factor activity
CMV14_RS10075	COG0022	dehydrogenase e1 component
CMV14_RS10080	COG1960	acyl-CoA dehydrogenase activity
CMV14_RS10085	COG1024	Enoyl-CoA hydratase
CMV14_RS10090	COG0318	PFAM AMP-dependent synthetase and ligase
CMV14_RS10105	COG1960	acyl-CoA dehydrogenase activity
CMV14_RS10110	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS10115	COG1024	Enoyl-CoA hydratase
CMV14_RS10130	COG1902	pentaerythritol trinitrate reductase activity
CMV14_RS10135	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CMV14_RS10155	COG2272	Belongs to the type-B carboxylesterase lipase family
CMV14_RS10175	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CMV14_RS10185	COG2030	dehydratase
CMV14_RS10195	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS10200	COG1960	acyl-CoA dehydrogenase activity
CMV14_RS10205	COG0318	PFAM AMP-dependent synthetase and ligase
CMV14_RS10210	COG1024	Enoyl-CoA hydratase
CMV14_RS10215	COG2070	2-Nitropropane dioxygenase
CMV14_RS10225	COG3335	DDE superfamily endonuclease
CMV14_RS10230	COG2154	pterin-4-alpha-carbinolamine dehydratase
CMV14_RS10250	COG2207	Transcriptional regulator
CMV14_RS10265	COG1309	transcriptional regulator
CMV14_RS10270	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS10280	COG0318	PFAM AMP-dependent synthetase and ligase
CMV14_RS10290	COG3971	2-oxopent-4-enoate hydratase activity
CMV14_RS10295	COG0583	DNA-binding transcription factor activity
CMV14_RS10305	COG4771	TonB-dependent receptor
CMV14_RS10325	COG3246	L-lysine catabolic process to acetate
CMV14_RS10355	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CMV14_RS10370	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CMV14_RS10370	COG0438	transferase activity, transferring glycosyl groups
CMV14_RS10380	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CMV14_RS10400	COG1881	PFAM PEBP family protein
CMV14_RS10415	COG1611	Belongs to the LOG family
CMV14_RS10460	COG0436	Aminotransferase
CMV14_RS10465	COG3243	poly(R)-hydroxyalkanoic acid synthase
CMV14_RS10475	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CMV14_RS10480	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CMV14_RS10490	COG0842	Transport permease protein
CMV14_RS10530	COG0386	Belongs to the glutathione peroxidase family
CMV14_RS10555	COG2967	ApaG domain
CMV14_RS10560	COG0583	DNA-binding transcription factor activity
CMV14_RS10570	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CMV14_RS10590	COG4191	Histidine kinase
CMV14_RS10590	COG0784	Response regulator, receiver
CMV14_RS10605	COG1704	LemA family
CMV14_RS10620	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CMV14_RS10625	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CMV14_RS10630	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CMV14_RS10635	COG0546	phosphoglycolate phosphatase activity
CMV14_RS10675	COG3022	response to hydroperoxide
CMV14_RS10685	COG1522	sequence-specific DNA binding
CMV14_RS10690	COG2202	Pas domain
CMV14_RS10690	COG2205	protein histidine kinase activity
CMV14_RS10720	COG1595	DNA-templated transcription, initiation
CMV14_RS10785	COG0729	surface antigen
CMV14_RS10800	COG1505	serine-type exopeptidase activity
CMV14_RS10805	COG2814	Major facilitator Superfamily
CMV14_RS10810	COG0174	glutamine synthetase
CMV14_RS10820	COG0024	Methionine aminopeptidase
CMV14_RS10825	COG1058	Belongs to the CinA family
CMV14_RS10825	COG1546	Belongs to the CinA family
CMV14_RS10845	COG0557	exoribonuclease II activity
CMV14_RS10865	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CMV14_RS10890	COG2824	Alkylphosphonate utilization operon protein PhnA
CMV14_RS10895	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CMV14_RS10900	COG0745	RESPONSE REGULATOR receiver
CMV14_RS10910	COG0752	glycyl-tRNA synthetase alpha subunit
CMV14_RS10915	COG2852	Protein conserved in bacteria
CMV14_RS10920	COG0751	glycine-tRNA ligase activity
CMV14_RS10925	COG0574	Belongs to the PEP-utilizing enzyme family
CMV14_RS10925	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CMV14_RS10930	COG2311	Membrane
CMV14_RS10950	COG2201	protein-glutamate methylesterase activity
CMV14_RS10960	COG4964	Belongs to the GSP D family
CMV14_RS10990	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CMV14_RS10995	COG0756	dUTP diphosphatase activity
CMV14_RS11000	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CMV14_RS11005	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CMV14_RS11010	COG2226	methyltransferase
CMV14_RS11015	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CMV14_RS11020	COG0268	Binds directly to 16S ribosomal RNA
CMV14_RS11025	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CMV14_RS11055	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CMV14_RS11060	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CMV14_RS11070	COG4974	Belongs to the 'phage' integrase family
CMV14_RS11075	COG0477	Major facilitator Superfamily
CMV14_RS11080	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CMV14_RS11085	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CMV14_RS11090	COG1127	ABC transporter
CMV14_RS11095	COG0678	peroxiredoxin activity
CMV14_RS11100	COG0625	glutathione transferase activity
CMV14_RS11110	COG0438	transferase activity, transferring glycosyl groups
CMV14_RS11120	COG1722	exodeoxyribonuclease VII activity
CMV14_RS11125	COG0142	geranyltranstransferase activity
CMV14_RS11130	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CMV14_RS11140	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CMV14_RS11160	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CMV14_RS11165	COG0105	UTP biosynthetic process
CMV14_RS11170	COG0456	acetyltransferase
CMV14_RS11185	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CMV14_RS11190	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CMV14_RS11205	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CMV14_RS11210	COG0671	phosphoesterase, PA-phosphatase related
CMV14_RS11215	COG0248	Ppx GppA phosphatase
CMV14_RS11220	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CMV14_RS11225	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CMV14_RS11250	COG2945	thiolester hydrolase activity
CMV14_RS11260	COG1104	cysteine desulfurase activity
CMV14_RS11275	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CMV14_RS11295	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CMV14_RS11300	COG0564	pseudouridine synthase activity
CMV14_RS11315	COG0643	Histidine kinase
CMV14_RS11315	COG2198	Histidine kinase
CMV14_RS11320	COG0835	chemotaxis
CMV14_RS11325	COG0745	RESPONSE REGULATOR receiver
CMV14_RS11330	COG2201	protein-glutamate methylesterase activity
CMV14_RS11335	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CMV14_RS11340	COG3023	N-Acetylmuramoyl-L-alanine amidase
CMV14_RS11355	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CMV14_RS11360	COG0009	L-threonylcarbamoyladenylate synthase
CMV14_RS11370	COG0778	Nitroreductase
CMV14_RS11375	COG3104	oligopeptide transport
CMV14_RS11380	COG1228	amidohydrolase
CMV14_RS11385	COG0804	urea catabolic process
CMV14_RS11390	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CMV14_RS11395	COG0352	thiamine-phosphate diphosphorylase activity
CMV14_RS11395	COG0351	phosphomethylpyrimidine kinase
CMV14_RS11400	COG1959	2 iron, 2 sulfur cluster binding
CMV14_RS11405	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CMV14_RS11405	COG1017	nitric oxide dioxygenase activity
CMV14_RS11420	COG0359	binds to the 23S rRNA
CMV14_RS11425	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CMV14_RS11430	COG0360	Binds together with S18 to 16S ribosomal RNA
CMV14_RS11440	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CMV14_RS11450	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CMV14_RS11455	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CMV14_RS11460	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CMV14_RS11490	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CMV14_RS11505	COG3158	transport of potassium into the cell
CMV14_RS11510	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CMV14_RS11530	COG0583	DNA-binding transcription factor activity
CMV14_RS11535	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CMV14_RS11540	COG5001	Diguanylate cyclase
CMV14_RS11565	COG0625	glutathione transferase activity
CMV14_RS11605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CMV14_RS11610	COG3608	succinylglutamate desuccinylase aspartoacylase
CMV14_RS11610	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CMV14_RS11615	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CMV14_RS11625	COG4181	ATPase activity
CMV14_RS11645	COG0604	alcohol dehydrogenase
CMV14_RS11670	COG0343	queuine tRNA-ribosyltransferase activity
CMV14_RS11695	COG0277	FAD linked oxidase domain protein
CMV14_RS11705	COG0513	Belongs to the DEAD box helicase family
CMV14_RS11710	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CMV14_RS11720	COG4251	negative regulation of phosphorylation
CMV14_RS11785	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CMV14_RS11790	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CMV14_RS11805	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CMV14_RS11830	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CMV14_RS11840	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CMV14_RS11845	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CMV14_RS11850	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CMV14_RS11855	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CMV14_RS11860	COG0071	Belongs to the small heat shock protein (HSP20) family
CMV14_RS11865	COG0825	malonyl-CoA metabolic process
CMV14_RS11890	COG0494	nUDIX hydrolase
CMV14_RS11900	COG2353	YceI-like domain
CMV14_RS11905	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CMV14_RS11915	COG0028	Belongs to the TPP enzyme family
CMV14_RS11920	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CMV14_RS11925	COG0560	Phosphoserine phosphatase
CMV14_RS11950	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CMV14_RS11955	COG0540	Belongs to the ATCase OTCase family
CMV14_RS11960	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CMV14_RS11970	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CMV14_RS11975	COG0154	amidase activity
CMV14_RS11980	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CMV14_RS11995	COG0544	peptidyl-prolyl cis-trans isomerase activity
CMV14_RS12005	COG0740	serine-type endopeptidase activity
CMV14_RS12010	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CMV14_RS12015	COG0840	transmembrane signaling receptor activity
CMV14_RS12030	COG0492	ferredoxin-NADP+ reductase activity
CMV14_RS12030	COG3118	belongs to the thioredoxin family
CMV14_RS12055	COG0302	gtp cyclohydrolase
CMV14_RS12065	COG0415	Belongs to the DNA photolyase family
CMV14_RS12070	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CMV14_RS12075	COG4221	oxidoreductase activity
CMV14_RS12080	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CMV14_RS12085	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CMV14_RS12090	COG0789	Transcriptional regulator
CMV14_RS12105	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CMV14_RS12115	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
CMV14_RS12125	COG0586	Pfam SNARE associated Golgi protein
CMV14_RS12130	COG0189	ligase activity
CMV14_RS12135	COG0792	nuclease activity
CMV14_RS12140	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CMV14_RS12150	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CMV14_RS12155	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CMV14_RS12160	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CMV14_RS12165	COG1420	regulation of RNA biosynthetic process
CMV14_RS12180	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CMV14_RS12190	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CMV14_RS12200	COG1040	competence protein
CMV14_RS12205	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CMV14_RS12210	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CMV14_RS12245	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CMV14_RS12280	COG3540	Alkaline phosphatase
CMV14_RS12305	COG0366	Alpha amylase catalytic
CMV14_RS12310	COG1523	belongs to the glycosyl hydrolase 13 family
CMV14_RS12315	COG0033	Phosphoglucomutase
CMV14_RS12320	COG0297	glycogen (starch) synthase activity
CMV14_RS12325	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CMV14_RS12330	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CMV14_RS12335	COG0058	SHG alpha-glucan phosphorylase activity
CMV14_RS12350	COG0531	amino acid
CMV14_RS12360	COG0457	Tetratricopeptide repeat
CMV14_RS12370	COG1012	belongs to the aldehyde dehydrogenase family
CMV14_RS12380	COG3724	N-succinylarginine dihydrolase activity
CMV14_RS12390	COG2860	membrane
CMV14_RS12400	COG1247	-acetyltransferase
CMV14_RS12405	COG0616	signal peptide processing
CMV14_RS12420	COG2308	Evidence 4 Homologs of previously reported genes of
CMV14_RS12425	COG0741	lytic transglycosylase activity
CMV14_RS12430	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CMV14_RS12435	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CMV14_RS12445	COG3590	peptidase
CMV14_RS12455	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CMV14_RS12475	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CMV14_RS12490	COG2264	protein methyltransferase activity
CMV14_RS12540	COG4774	siderophore transport
CMV14_RS12555	COG0582	viral genome integration into host DNA
CMV14_RS12575	COG4584	PFAM Integrase catalytic
CMV14_RS12585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CMV14_RS12590	COG1131	(ABC) transporter
CMV14_RS12595	COG0842	Transport permease protein
CMV14_RS12600	COG0842	Transport permease protein
CMV14_RS12615	COG4771	TonB-dependent receptor
CMV14_RS12620	COG1012	belongs to the aldehyde dehydrogenase family
CMV14_RS12630	COG2814	Major facilitator Superfamily
CMV14_RS12635	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CMV14_RS12645	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CMV14_RS12650	COG4771	TonB-dependent receptor
CMV14_RS12655	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CMV14_RS12660	COG2197	response regulator
CMV14_RS12675	COG3916	Acyl-homoserine-lactone synthase
CMV14_RS12690	COG4959	Type IV secretory pathway protease TraF
CMV14_RS12695	COG0739	heme binding
CMV14_RS12695	COG0741	lytic transglycosylase activity
CMV14_RS12695	COG1196	nuclear chromosome segregation
CMV14_RS12740	COG4227	nucleotidyltransferase activity
CMV14_RS12760	COG0798	PFAM Bile acid sodium symporter
CMV14_RS12770	COG1475	DNA binding
CMV14_RS12805	COG4691	Plasmid stability protein
CMV14_RS12810	COG1487	ribonuclease activity
CMV14_RS12825	COG5489	Protein of unknown function (DUF736)
CMV14_RS12880	COG1192	Involved in chromosome partitioning
CMV14_RS12905	COG0741	lytic transglycosylase activity
CMV14_RS12925	COG4962	Type ii secretion system protein e
CMV14_RS12940	COG3451	type IV secretory pathway VirB4
CMV14_RS12955	COG3846	protein secretion by the type IV secretion system
CMV14_RS12970	COG2948	multi-organism process
CMV14_RS12980	COG0583	DNA-binding transcription factor activity
CMV14_RS13015	COG2948	multi-organism process
CMV14_RS13020	COG3504	Conjugal transfer protein
CMV14_RS13030	COG3846	protein secretion by the type IV secretion system
CMV14_RS13055	COG0210	DNA helicase
CMV14_RS13060	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CMV14_RS13065	COG3451	type IV secretory pathway VirB4
CMV14_RS13075	COG3838	Conjugal transfer protein Trbc
CMV14_RS13080	COG4962	Type ii secretion system protein e
CMV14_RS13120	COG0633	Ferredoxin
CMV14_RS13125	COG2124	cytochrome p450
CMV14_RS13155	COG1476	TRANSCRIPTIONal
CMV14_RS13190	COG4227	nucleotidyltransferase activity
CMV14_RS13210	COG0798	PFAM Bile acid sodium symporter
CMV14_RS13215	COG4227	nucleotidyltransferase activity
CMV14_RS13230	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CMV14_RS13255	COG0326	Molecular chaperone. Has ATPase activity
CMV14_RS13305	COG0772	Belongs to the SEDS family
CMV14_RS13330	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CMV14_RS13340	COG0321	lipoyl(octanoyl) transferase activity
CMV14_RS13340	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CMV14_RS13345	COG0084	hydrolase, TatD family'
CMV14_RS13360	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CMV14_RS13365	COG1686	Belongs to the peptidase S11 family
CMV14_RS13375	COG2951	lytic endotransglycosylase activity
CMV14_RS13400	COG0254	rRNA binding
CMV14_RS13405	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CMV14_RS13420	COG0750	zinc metalloprotease
CMV14_RS13425	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CMV14_RS13435	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CMV14_RS13440	COG0233	cytoplasmic translational termination
CMV14_RS13445	COG0528	UMP kinase activity
CMV14_RS13450	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CMV14_RS13455	COG0052	Belongs to the universal ribosomal protein uS2 family
CMV14_RS13465	COG1183	phosphatidylcholine synthase activity
CMV14_RS13470	COG0688	phosphatidylethanolamine metabolic process
CMV14_RS13475	COG0538	isocitrate dehydrogenase activity
CMV14_RS13480	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CMV14_RS13480	COG4651	solute:proton antiporter activity
CMV14_RS13485	COG0475	glutathione-regulated potassium exporter activity
CMV14_RS13485	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CMV14_RS13490	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CMV14_RS13490	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CMV14_RS13500	COG2814	Major facilitator Superfamily
CMV14_RS13505	COG0138	bifunctional purine biosynthesis protein purh
CMV14_RS13510	COG5002	protein histidine kinase activity
CMV14_RS13515	COG0148	phosphopyruvate hydratase activity
CMV14_RS13550	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CMV14_RS13565	COG0505	Belongs to the CarA family
CMV14_RS13575	COG2827	Endonuclease containing a URI domain
CMV14_RS13585	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CMV14_RS13605	COG1477	protein flavinylation
CMV14_RS13610	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CMV14_RS13615	COG0047	phosphoribosylformylglycinamidine synthase activity
CMV14_RS13625	COG1742	UPF0060 membrane protein
CMV14_RS13650	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CMV14_RS13660	COG1294	oxidase, subunit
CMV14_RS13680	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CMV14_RS13690	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CMV14_RS13705	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CMV14_RS13710	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CMV14_RS13720	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CMV14_RS13720	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CMV14_RS13730	COG2199	diguanylate cyclase activity
CMV14_RS13740	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CMV14_RS13745	COG0745	RESPONSE REGULATOR receiver
CMV14_RS13750	COG2205	protein histidine kinase activity
CMV14_RS13760	COG1660	Displays ATPase and GTPase activities
CMV14_RS13765	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CMV14_RS13775	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CMV14_RS13825	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CMV14_RS13835	COG2003	Belongs to the UPF0758 family
CMV14_RS13850	COG0070	glutamate synthase
CMV14_RS13850	COG0067	glutamate synthase
CMV14_RS13850	COG0069	glutamate synthase activity
CMV14_RS13865	COG1217	gtp-binding protein TYPA
CMV14_RS13885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CMV14_RS13890	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CMV14_RS13905	COG0583	DNA-binding transcription factor activity
CMV14_RS13910	COG3956	TIGRFAM MazG family protein
CMV14_RS13915	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CMV14_RS13920	COG1923	regulation of RNA biosynthetic process
CMV14_RS13925	COG2204	response regulator
CMV14_RS13930	COG5000	phosphorelay sensor kinase activity
CMV14_RS13950	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CMV14_RS13950	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CMV14_RS13955	COG1546	Belongs to the CinA family
CMV14_RS13955	COG1058	Belongs to the CinA family
CMV14_RS13960	COG2867	negative regulation of translational initiation
CMV14_RS13965	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CMV14_RS13970	COG0288	reversible hydration of carbon dioxide
CMV14_RS13980	COG0488	(ABC) transporter
CMV14_RS14005	COG3920	Histidine kinase
CMV14_RS14010	COG0625	glutathione transferase activity
CMV14_RS14030	COG1322	Protein conserved in bacteria
CMV14_RS14035	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CMV14_RS14045	COG0215	cysteine-tRNA ligase activity
CMV14_RS14055	COG1012	belongs to the aldehyde dehydrogenase family
CMV14_RS14085	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CMV14_RS14100	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CMV14_RS14115	COG1987	bacterial-type flagellum assembly
CMV14_RS14120	COG1684	flagellar biosynthetic protein fliR
CMV14_RS14125	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CMV14_RS14150	COG0571	ribonuclease III activity
CMV14_RS14155	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CMV14_RS14200	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CMV14_RS14205	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CMV14_RS14215	COG0659	secondary active sulfate transmembrane transporter activity
CMV14_RS14225	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CMV14_RS14230	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CMV14_RS14235	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CMV14_RS14240	COG2080	2 iron, 2 sulfur cluster binding
CMV14_RS14245	COG4948	Mandelate Racemase Muconate Lactonizing
CMV14_RS14260	COG1132	(ABC) transporter
CMV14_RS14270	COG1024	Enoyl-CoA hydratase
CMV14_RS14275	COG1024	Enoyl-CoA hydratase
CMV14_RS14280	COG1960	acyl-CoA dehydrogenase activity
CMV14_RS14300	COG0784	Response regulator, receiver
CMV14_RS14315	COG0784	Response regulator, receiver
CMV14_RS14330	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CMV14_RS14340	COG2986	histidine ammonia-lyase
CMV14_RS14345	COG1228	amidohydrolase
CMV14_RS14385	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CMV14_RS14390	COG0667	Aldo Keto reductase
CMV14_RS14395	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CMV14_RS14430	COG3932	Exopolysaccharide synthesis, ExoD
CMV14_RS14435	COG0179	Fumarylacetoacetate (FAA) hydrolase
CMV14_RS14470	COG1053	succinate dehydrogenase
CMV14_RS14485	COG3246	L-lysine catabolic process to acetate
CMV14_RS14490	COG0477	Major facilitator Superfamily
CMV14_RS14495	COG1250	3-hydroxyacyl-CoA dehydrogenase
CMV14_RS14515	COG2124	cytochrome p450
CMV14_RS14550	COG2271	Major facilitator Superfamily
CMV14_RS14575	COG1053	succinate dehydrogenase
CMV14_RS14585	COG0625	glutathione transferase activity
CMV14_RS14605	COG1053	succinate dehydrogenase
CMV14_RS14625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CMV14_RS14635	COG0179	Fumarylacetoacetate (FAA) hydrolase
CMV14_RS14650	COG4771	TonB-dependent receptor
CMV14_RS14655	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS14665	COG2267	carboxylic ester hydrolase activity
CMV14_RS14670	COG0318	PFAM AMP-dependent synthetase and ligase
CMV14_RS14675	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CMV14_RS14690	COG0183	Belongs to the thiolase family
CMV14_RS14725	COG3971	2-oxopent-4-enoate hydratase activity
CMV14_RS14730	COG1012	belongs to the aldehyde dehydrogenase family
CMV14_RS14740	COG4774	siderophore transport
CMV14_RS14745	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CMV14_RS14750	COG0196	riboflavin kinase activity
CMV14_RS14835	COG0006	proline dipeptidase activity
CMV14_RS14840	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CMV14_RS14850	COG0113	porphobilinogen synthase activity
CMV14_RS14875	COG0534	Mate efflux family protein
CMV14_RS14880	COG0525	valine-tRNA ligase activity
CMV14_RS14885	COG0823	Involved in the tonB-independent uptake of proteins
CMV14_RS14885	COG1506	peptidase
CMV14_RS14900	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CMV14_RS14920	COG3920	Histidine kinase
CMV14_RS14925	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CMV14_RS14930	COG0581	inorganic phosphate transmembrane transporter activity
CMV14_RS14935	COG0573	inorganic phosphate transmembrane transporter activity
CMV14_RS14940	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CMV14_RS14945	COG3746	phosphate-selective porin O and P
CMV14_RS14960	COG4941	Belongs to the sigma-70 factor family
CMV14_RS14965	COG3795	YCII-related domain
CMV14_RS15000	COG2311	Membrane
CMV14_RS15005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CMV14_RS15010	COG0587	DNA-directed DNA polymerase activity
CMV14_RS15035	COG3077	Addiction module antitoxin, RelB DinJ family
CMV14_RS15055	COG3220	belongs to the UPF0276 family
CMV14_RS15065	COG4944	Protein of unknown function (DUF1109)
CMV14_RS15085	COG1252	NADH dehydrogenase
CMV14_RS15095	COG0784	Response regulator, receiver
CMV14_RS15095	COG4191	Histidine kinase
CMV14_RS15115	COG0583	DNA-binding transcription factor activity
CMV14_RS15120	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS15130	COG2133	pyrroloquinoline quinone binding
CMV14_RS15155	COG2818	Glycosylase
CMV14_RS15165	COG0556	nucleotide-excision repair
CMV14_RS15185	COG0477	Major facilitator Superfamily
CMV14_RS15210	COG3186	Phenylalanine-4-hydroxylase
CMV14_RS15225	COG1230	cation diffusion facilitator family transporter
CMV14_RS15235	COG1899	peptidyl-lysine modification to peptidyl-hypusine
CMV14_RS15255	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CMV14_RS15260	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CMV14_RS15260	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CMV14_RS15270	COG0583	DNA-binding transcription factor activity
CMV14_RS15325	COG0004	ammonium transporteR
CMV14_RS15330	COG0778	Nitroreductase
CMV14_RS15335	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CMV14_RS15345	COG2321	neutral zinc metallopeptidase
CMV14_RS15360	COG0515	serine threonine protein kinase
CMV14_RS15400	COG1793	dna ligase
CMV14_RS15415	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS15420	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CMV14_RS15435	COG1612	heme a metabolic process
CMV14_RS15440	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CMV14_RS15445	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CMV14_RS15500	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CMV14_RS15520	COG1494	fructose-1,6-bisphosphatase
CMV14_RS15535	COG1764	response to oxidative stress
CMV14_RS15555	COG0497	DNA recombination
CMV14_RS15575	COG4999	Histidine kinase
CMV14_RS15575	COG3850	Histidine kinase
CMV14_RS15575	COG2205	protein histidine kinase activity
CMV14_RS15575	COG3437	response regulator, receiver
CMV14_RS15585	COG1794	racemase activity, acting on amino acids and derivatives
CMV14_RS15590	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CMV14_RS15605	COG0513	Belongs to the DEAD box helicase family
CMV14_RS15640	COG1968	undecaprenyl-diphosphatase activity
CMV14_RS15655	COG0582	viral genome integration into host DNA
CMV14_RS15675	COG2948	multi-organism process
CMV14_RS15685	COG3701	Conjugal transfer protein
CMV14_RS15690	COG3846	protein secretion by the type IV secretion system
CMV14_RS15700	COG3451	type IV secretory pathway VirB4
CMV14_RS15715	COG4962	Type ii secretion system protein e
CMV14_RS15740	COG0419	ATPase involved in DNA repair
CMV14_RS15750	COG1104	cysteine desulfurase activity
CMV14_RS15780	COG0798	PFAM Bile acid sodium symporter
CMV14_RS15800	COG4227	nucleotidyltransferase activity
CMV14_RS15840	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CMV14_RS15860	COG0028	Belongs to the TPP enzyme family
CMV14_RS15895	COG4638	Rieske (2fe-2S)
CMV14_RS15955	COG4948	Mandelate Racemase Muconate Lactonizing
CMV14_RS15980	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS15985	COG4773	Receptor
CMV14_RS16005	COG4773	Receptor
CMV14_RS16015	COG1522	sequence-specific DNA binding
CMV14_RS16040	COG2124	cytochrome p450
CMV14_RS16045	COG2207	Transcriptional regulator
CMV14_RS16075	COG4771	TonB-dependent receptor
CMV14_RS16095	COG4584	PFAM Integrase catalytic
CMV14_RS16110	COG1454	alcohol dehydrogenase
CMV14_RS16120	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CMV14_RS16125	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CMV14_RS16135	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CMV14_RS16145	COG1012	belongs to the aldehyde dehydrogenase family
CMV14_RS16155	COG4771	TonB-dependent receptor
CMV14_RS16170	COG4584	PFAM Integrase catalytic
CMV14_RS16175	COG4771	TonB-dependent receptor
CMV14_RS16205	COG0745	RESPONSE REGULATOR receiver
CMV14_RS16225	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS16250	COG0582	viral genome integration into host DNA
CMV14_RS16320	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CMV14_RS16370	COG1802	Transcriptional regulator
CMV14_RS16375	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CMV14_RS16385	COG4771	TonB-dependent receptor
CMV14_RS16390	COG1228	amidohydrolase
CMV14_RS16395	COG2814	Major facilitator Superfamily
CMV14_RS16400	COG0823	Involved in the tonB-independent uptake of proteins
CMV14_RS16400	COG4946	Tricorn protease homolog
CMV14_RS16400	COG1506	peptidase
CMV14_RS16405	COG2423	ornithine cyclodeaminase activity
CMV14_RS16435	COG2814	Major facilitator Superfamily
CMV14_RS16440	COG4771	TonB-dependent receptor
CMV14_RS16445	COG0583	DNA-binding transcription factor activity
CMV14_RS16450	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CMV14_RS16465	COG3158	transport of potassium into the cell
CMV14_RS16475	COG0745	RESPONSE REGULATOR receiver
CMV14_RS16480	COG2205	protein histidine kinase activity
CMV14_RS16490	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CMV14_RS16495	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CMV14_RS16515	COG1301	dicarboxylic acid transport
CMV14_RS16535	COG4774	siderophore transport
CMV14_RS16550	COG1228	amidohydrolase
CMV14_RS16590	COG2124	cytochrome p450
CMV14_RS16610	COG4771	TonB-dependent receptor
CMV14_RS16615	COG2207	Transcriptional regulator
CMV14_RS16620	COG2814	Major facilitator Superfamily
CMV14_RS16630	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS16635	COG0625	glutathione transferase activity
CMV14_RS16640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CMV14_RS16670	COG0625	glutathione transferase activity
CMV14_RS16700	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CMV14_RS16710	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CMV14_RS16720	COG1609	Transcriptional regulator
CMV14_RS16720	COG2207	Transcriptional regulator
CMV14_RS16735	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS16750	COG0667	Aldo Keto reductase
CMV14_RS16765	COG0235	Class ii aldolase
CMV14_RS16770	COG2124	cytochrome p450
CMV14_RS16775	COG3976	FMN-binding domain protein
CMV14_RS16775	COG1053	succinate dehydrogenase
CMV14_RS16785	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS16795	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CMV14_RS16805	COG1053	succinate dehydrogenase
CMV14_RS16810	COG0022	dehydrogenase e1 component
CMV14_RS16820	COG2267	carboxylic ester hydrolase activity
CMV14_RS16840	COG0346	lactoylglutathione lyase activity
CMV14_RS16845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CMV14_RS16855	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS16870	COG0667	Aldo Keto reductase
CMV14_RS16875	COG0572	uridine kinase
CMV14_RS16880	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CMV14_RS16890	COG4977	sequence-specific DNA binding
CMV14_RS16895	COG0596	Alpha beta hydrolase
CMV14_RS16900	COG1012	belongs to the aldehyde dehydrogenase family
CMV14_RS16925	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CMV14_RS16945	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CMV14_RS16950	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CMV14_RS16955	COG0584	glycerophosphoryl diester phosphodiesterase
CMV14_RS16960	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CMV14_RS16980	COG0066	3-isopropylmalate dehydratase activity
CMV14_RS16985	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CMV14_RS16990	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CMV14_RS16995	COG4191	Histidine kinase
CMV14_RS16995	COG0784	Response regulator, receiver
CMV14_RS17025	COG2022	thiamine diphosphate biosynthetic process
CMV14_RS17030	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CMV14_RS17035	COG0511	ligase activity, forming carbon-carbon bonds
CMV14_RS17040	COG0439	Biotin carboxylase
CMV14_RS17045	COG1393	Belongs to the ArsC family
CMV14_RS17050	COG1196	nuclear chromosome segregation
CMV14_RS17080	COG1605	Chorismate mutase
CMV14_RS17080	COG0077	Prephenate dehydratase
CMV14_RS17085	COG3474	cytochrome
CMV14_RS17095	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CMV14_RS17105	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CMV14_RS17110	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CMV14_RS17125	COG0330	HflC and HflK could
CMV14_RS17165	COG0730	response to heat
CMV14_RS17180	COG0175	sulfate reduction
CMV14_RS17200	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CMV14_RS17205	COG5001	Diguanylate cyclase
CMV14_RS17210	COG1393	Belongs to the ArsC family
CMV14_RS17215	COG1496	oxidoreductase activity
CMV14_RS17220	COG1254	Belongs to the acylphosphatase family
CMV14_RS17225	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CMV14_RS17230	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CMV14_RS17235	COG1295	ribonuclease BN
CMV14_RS17240	COG0484	heat shock protein binding
CMV14_RS17290	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CMV14_RS17295	COG0259	pyridoxamine-phosphate oxidase activity
CMV14_RS17300	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CMV14_RS17310	COG0482	sulfurtransferase activity
CMV14_RS17355	COG2733	membrane
CMV14_RS17370	COG0784	Response regulator, receiver
CMV14_RS17370	COG2198	Histidine kinase
CMV14_RS17370	COG2205	protein histidine kinase activity
CMV14_RS17425	COG0670	Belongs to the BI1 family
CMV14_RS17435	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CMV14_RS17440	COG2032	superoxide dismutase activity
CMV14_RS17445	COG2885	chlorophyll binding
CMV14_RS17445	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CMV14_RS17475	COG0187	DNA topoisomerase II activity
CMV14_RS17480	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CMV14_RS17490	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CMV14_RS17500	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CMV14_RS17510	COG2879	small protein
CMV14_RS17515	COG1966	Carbon starvation protein
CMV14_RS17525	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CMV14_RS17535	COG2175	clavaminate synthase activity
CMV14_RS17540	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS17550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CMV14_RS17555	COG1960	acyl-CoA dehydrogenase activity
CMV14_RS17560	COG3971	2-oxopent-4-enoate hydratase activity
CMV14_RS17565	COG0028	Belongs to the TPP enzyme family
CMV14_RS17575	COG1522	sequence-specific DNA binding
CMV14_RS17585	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CMV14_RS17670	COG0037	tRNA processing
CMV14_RS17685	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CMV14_RS17690	COG2070	2-Nitropropane dioxygenase
CMV14_RS17695	COG0527	aspartate kinase activity
CMV14_RS17700	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CMV14_RS17715	COG1482	cell wall glycoprotein biosynthetic process
CMV14_RS17730	COG3275	phosphorelay sensor kinase activity
CMV14_RS17740	COG0473	3-isopropylmalate dehydrogenase activity
CMV14_RS17745	COG1381	Involved in DNA repair and RecF pathway recombination
CMV14_RS17750	COG0322	excinuclease ABC activity
CMV14_RS17760	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CMV14_RS17765	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CMV14_RS17775	COG0356	it plays a direct role in the translocation of protons across the membrane
CMV14_RS17785	COG4771	TonB-dependent receptor
CMV14_RS17795	COG4191	Histidine kinase
CMV14_RS17795	COG0784	Response regulator, receiver
CMV14_RS17825	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CMV14_RS17825	COG0517	IMP dehydrogenase activity
CMV14_RS17830	COG2003	Belongs to the UPF0758 family
CMV14_RS17860	COG2176	DNA-directed DNA polymerase activity
CMV14_RS17865	COG1074	ATP-dependent DNA helicase activity
CMV14_RS17905	COG4227	nucleotidyltransferase activity
CMV14_RS17925	COG0798	PFAM Bile acid sodium symporter
CMV14_RS17940	COG1475	DNA binding
CMV14_RS17945	COG5489	Protein of unknown function (DUF736)
CMV14_RS18030	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CMV14_RS18040	COG0582	viral genome integration into host DNA
CMV14_RS18195	COG2197	response regulator
CMV14_RS18200	COG0842	Transport permease protein
CMV14_RS18205	COG1129	ABC transporter
CMV14_RS18205	COG0842	Transport permease protein
CMV14_RS18210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CMV14_RS18225	COG1137	ATPase activity
CMV14_RS18230	COG3243	poly(R)-hydroxyalkanoic acid synthase
CMV14_RS18240	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CMV14_RS18245	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
CMV14_RS18265	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CMV14_RS18385	COG0210	DNA helicase
CMV14_RS18400	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CMV14_RS18415	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CMV14_RS18430	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CMV14_RS18435	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CMV14_RS18455	COG0432	Pfam Uncharacterised protein family UPF0047
CMV14_RS18515	COG1115	amino acid carrier protein
CMV14_RS18525	COG1045	serine acetyltransferase
CMV14_RS18545	COG1618	nucleotide phosphatase activity, acting on free nucleotides
CMV14_RS18545	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CMV14_RS18555	COG1231	oxidoreductase activity
CMV14_RS18560	COG1012	belongs to the aldehyde dehydrogenase family
CMV14_RS18575	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CMV14_RS18585	COG1309	transcriptional regulator
CMV14_RS18605	COG1024	Enoyl-CoA hydratase
CMV14_RS18615	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS18620	COG2124	cytochrome p450
CMV14_RS18625	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CMV14_RS18650	COG0625	glutathione transferase activity
CMV14_RS18670	COG1309	transcriptional regulator
CMV14_RS18705	COG0673	inositol 2-dehydrogenase activity
CMV14_RS18765	COG0489	protein tyrosine kinase activity
CMV14_RS18765	COG3206	protein involved in exopolysaccharide biosynthesis
CMV14_RS18775	COG4584	PFAM Integrase catalytic
CMV14_RS18800	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CMV14_RS18805	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CMV14_RS18815	COG5410	chromosome segregation
CMV14_RS18855	COG2030	dehydratase
CMV14_RS18860	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS18865	COG0183	Belongs to the thiolase family
CMV14_RS18895	COG1309	transcriptional regulator
CMV14_RS18905	COG2814	Major facilitator Superfamily
CMV14_RS18920	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CMV14_RS18935	COG2197	response regulator
CMV14_RS18940	COG1454	alcohol dehydrogenase
CMV14_RS18955	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CMV14_RS18970	COG0318	PFAM AMP-dependent synthetase and ligase
CMV14_RS18975	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS18980	COG2124	cytochrome p450
CMV14_RS19005	COG1960	acyl-CoA dehydrogenase activity
CMV14_RS19015	COG0183	Belongs to the thiolase family
CMV14_RS19035	COG1960	acyl-CoA dehydrogenase activity
CMV14_RS19055	COG2130	NADP-dependent
CMV14_RS19070	COG1802	Transcriptional regulator
CMV14_RS19075	COG1012	belongs to the aldehyde dehydrogenase family
CMV14_RS19080	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CMV14_RS19175	COG5489	Protein of unknown function (DUF736)
CMV14_RS19220	COG0741	lytic transglycosylase activity
CMV14_RS19240	COG4962	Type ii secretion system protein e
CMV14_RS19255	COG3451	type IV secretory pathway VirB4
CMV14_RS19315	COG0745	RESPONSE REGULATOR receiver
CMV14_RS19320	COG2205	protein histidine kinase activity
CMV14_RS19350	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CMV14_RS19355	COG1309	transcriptional regulator
CMV14_RS19365	COG0402	S-adenosylhomocysteine deaminase activity
CMV14_RS19375	COG1012	belongs to the aldehyde dehydrogenase family
CMV14_RS19380	COG0179	Fumarylacetoacetate (FAA) hydrolase
CMV14_RS19390	COG1802	Transcriptional regulator
CMV14_RS19395	COG4302	ethanolamine ammonia-lyase activity
CMV14_RS19405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CMV14_RS19415	COG0402	S-adenosylhomocysteine deaminase activity
CMV14_RS19420	COG4771	TonB-dependent receptor
CMV14_RS19425	COG1309	transcriptional regulator
CMV14_RS19430	COG2814	Major facilitator Superfamily
CMV14_RS19445	COG1012	belongs to the aldehyde dehydrogenase family
CMV14_RS19450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CMV14_RS19455	COG4771	TonB-dependent receptor
CMV14_RS19480	COG2207	Transcriptional regulator
CMV14_RS19485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CMV14_RS19490	COG0437	4 iron, 4 sulfur cluster binding
CMV14_RS19495	COG0243	molybdopterin cofactor binding
CMV14_RS19500	COG1250	3-hydroxyacyl-CoA dehydrogenase
CMV14_RS19500	COG1024	Enoyl-CoA hydratase
CMV14_RS19505	COG0183	Belongs to the thiolase family
CMV14_RS19515	COG1024	Enoyl-CoA hydratase
CMV14_RS19525	COG4771	TonB-dependent receptor
CMV14_RS19550	COG0235	Class ii aldolase
CMV14_RS19555	COG1024	Enoyl-CoA hydratase
CMV14_RS19560	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS19565	COG0346	lactoylglutathione lyase activity
CMV14_RS19570	COG2814	Major facilitator Superfamily
CMV14_RS19590	COG2086	electron transfer activity
CMV14_RS19595	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CMV14_RS19600	COG1902	pentaerythritol trinitrate reductase activity
CMV14_RS19605	COG2175	clavaminate synthase activity
CMV14_RS19620	COG1960	acyl-CoA dehydrogenase activity
CMV14_RS19640	COG0402	S-adenosylhomocysteine deaminase activity
CMV14_RS19645	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CMV14_RS19660	COG3916	Acyl-homoserine-lactone synthase
CMV14_RS19705	COG4227	nucleotidyltransferase activity
CMV14_RS19750	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CMV14_RS19755	COG2124	cytochrome p450
CMV14_RS19760	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CMV14_RS19775	COG4962	Type ii secretion system protein e
CMV14_RS19780	COG3838	Conjugal transfer protein Trbc
CMV14_RS19790	COG3451	type IV secretory pathway VirB4
CMV14_RS19800	COG3846	protein secretion by the type IV secretion system
CMV14_RS19815	COG2948	multi-organism process
CMV14_RS19845	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CMV14_RS19845	COG2111	Na H antiporter
CMV14_RS19850	COG1006	Multisubunit Na H antiporter MnhC subunit
CMV14_RS19855	COG0651	ATP synthesis coupled electron transport
CMV14_RS19860	COG1863	multisubunit Na H antiporter MnhE subunit
CMV14_RS19865	COG2212	antiporter activity
CMV14_RS19870	COG1320	monovalent cation:proton antiporter activity
CMV14_RS19875	COG1309	transcriptional regulator
CMV14_RS19890	COG0583	DNA-binding transcription factor activity
CMV14_RS19895	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CMV14_RS19900	COG0318	PFAM AMP-dependent synthetase and ligase
CMV14_RS19925	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS19935	COG1309	transcriptional regulator
CMV14_RS19955	COG1024	Enoyl-CoA hydratase
CMV14_RS19965	COG1960	acyl-CoA dehydrogenase activity
CMV14_RS19975	COG2124	cytochrome p450
CMV14_RS19990	COG0583	DNA-binding transcription factor activity
CMV14_RS19995	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS20010	COG2124	cytochrome p450
CMV14_RS20030	COG4221	oxidoreductase activity
CMV14_RS20035	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CMV14_RS20040	COG0477	Major facilitator Superfamily
CMV14_RS20050	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS20060	COG0277	FAD linked oxidase domain protein
CMV14_RS20065	COG0277	FAD linked oxidase domain protein
CMV14_RS20070	COG0247	lactate metabolic process
CMV14_RS20115	COG4221	oxidoreductase activity
CMV14_RS20120	COG0438	transferase activity, transferring glycosyl groups
CMV14_RS20130	COG0840	transmembrane signaling receptor activity
CMV14_RS20135	COG1024	Enoyl-CoA hydratase
CMV14_RS20150	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CMV14_RS20155	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CMV14_RS20170	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CMV14_RS20190	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CMV14_RS20210	COG0746	molybdenum cofactor guanylyltransferase activity
CMV14_RS20215	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CMV14_RS20225	COG3383	formate dehydrogenase (NAD+) activity
CMV14_RS20240	COG0583	DNA-binding transcription factor activity
CMV14_RS20280	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS20320	COG2770	Histidine kinase
CMV14_RS20320	COG2208	phosphoserine phosphatase activity
CMV14_RS20365	COG5001	Diguanylate cyclase
CMV14_RS20365	COG3300	MHYT domain
CMV14_RS20370	COG0412	Dienelactone hydrolase
CMV14_RS20375	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
CMV14_RS20420	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CMV14_RS20420	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CMV14_RS20480	COG0477	Major facilitator Superfamily
CMV14_RS20490	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CMV14_RS20495	COG2201	protein-glutamate methylesterase activity
CMV14_RS20500	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CMV14_RS20510	COG2175	clavaminate synthase activity
CMV14_RS20520	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS20530	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS20540	COG0446	pyridine nucleotide-disulphide oxidoreductase
CMV14_RS20540	COG1902	pentaerythritol trinitrate reductase activity
CMV14_RS20545	COG1024	Enoyl-CoA hydratase
CMV14_RS20575	COG4771	TonB-dependent receptor
CMV14_RS20590	COG0633	Ferredoxin
CMV14_RS20605	COG1309	transcriptional regulator
CMV14_RS20630	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CMV14_RS20635	COG0318	PFAM AMP-dependent synthetase and ligase
CMV14_RS20650	COG4774	siderophore transport
CMV14_RS20670	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS20675	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CMV14_RS20700	COG4774	siderophore transport
CMV14_RS20710	COG0183	Belongs to the thiolase family
CMV14_RS20730	COG2079	MmgE PrpD family protein
CMV14_RS20740	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CMV14_RS20750	COG1960	acyl-CoA dehydrogenase activity
CMV14_RS20755	COG2030	dehydratase
CMV14_RS20760	COG1024	Enoyl-CoA hydratase
CMV14_RS20765	COG1960	acyl-CoA dehydrogenase activity
CMV14_RS20770	COG1960	acyl-CoA dehydrogenase activity
CMV14_RS20780	COG1309	transcriptional regulator
CMV14_RS20790	COG2030	dehydratase
CMV14_RS20800	COG1960	acyl-CoA dehydrogenase activity
CMV14_RS20840	COG0436	Aminotransferase
CMV14_RS20845	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CMV14_RS20860	COG4206	TonB-dependent receptor
CMV14_RS20905	COG3158	transport of potassium into the cell
CMV14_RS20910	COG1522	sequence-specific DNA binding
CMV14_RS20915	COG0686	Belongs to the AlaDH PNT family
CMV14_RS20925	COG3088	subunit of a heme lyase
CMV14_RS20930	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CMV14_RS20935	COG1138	Cytochrome C-type biogenesis protein
CMV14_RS20940	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CMV14_RS20950	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CMV14_RS20970	COG1959	2 iron, 2 sulfur cluster binding
CMV14_RS20990	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CMV14_RS21010	COG1793	dna ligase
CMV14_RS21070	COG1058	Belongs to the CinA family
CMV14_RS21070	COG1546	Belongs to the CinA family
CMV14_RS21075	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CMV14_RS21080	COG2852	Protein conserved in bacteria
CMV14_RS21085	COG5001	Diguanylate cyclase
CMV14_RS21090	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CMV14_RS21100	COG0517	IMP dehydrogenase activity
CMV14_RS21100	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CMV14_RS21105	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CMV14_RS21120	COG3273	potassium ion transport
CMV14_RS21120	COG0471	metal ion transport
CMV14_RS21125	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CMV14_RS21150	COG2001	Belongs to the MraZ family
CMV14_RS21155	COG0275	rRNA processing
CMV14_RS21170	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CMV14_RS21175	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CMV14_RS21180	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CMV14_RS21185	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CMV14_RS21195	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CMV14_RS21200	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CMV14_RS21210	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CMV14_RS21215	COG1181	Belongs to the D-alanine--D-alanine ligase family
CMV14_RS21220	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CMV14_RS21225	COG0849	cell division
CMV14_RS21230	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CMV14_RS21235	COG0457	Tetratricopeptide repeat
CMV14_RS21245	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CMV14_RS21255	COG0018	arginyl-trna synthetase
CMV14_RS21265	COG1472	Belongs to the glycosyl hydrolase 3 family
CMV14_RS21270	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CMV14_RS21275	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CMV14_RS21280	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CMV14_RS21285	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CMV14_RS21290	COG0805	protein transport
CMV14_RS21310	COG0784	Response regulator, receiver
CMV14_RS21320	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CMV14_RS21325	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CMV14_RS21330	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CMV14_RS21340	COG0657	acetylesterase activity
CMV14_RS21345	COG0123	including yeast histone deacetylase and acetoin utilization protein
CMV14_RS21350	COG2833	Protein of unknown function (DUF455)
CMV14_RS21355	COG0739	heme binding
CMV14_RS21360	COG0316	Belongs to the HesB IscA family
CMV14_RS21375	COG1280	lysine exporter protein (LysE YggA)
CMV14_RS21380	COG0456	acetyltransferase
CMV14_RS21445	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CMV14_RS21450	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CMV14_RS21465	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CMV14_RS21470	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CMV14_RS21485	COG1492	cobalamin metabolic process
CMV14_RS21520	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
CMV14_RS21525	COG0109	protoheme IX farnesyltransferase activity
CMV14_RS21530	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CMV14_RS21540	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CMV14_RS21545	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CMV14_RS21550	COG0736	holo-[acyl-carrier-protein] synthase activity
CMV14_RS21555	COG0681	Belongs to the peptidase S26 family
CMV14_RS21565	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CMV14_RS21590	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
CMV14_RS21595	COG1199	ATP-dependent helicase activity
CMV14_RS21595	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CMV14_RS21615	COG4773	Receptor
CMV14_RS21630	COG0776	regulation of translation
CMV14_RS21635	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CMV14_RS21640	COG0416	fatty acid biosynthetic process
CMV14_RS21645	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CMV14_RS21655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CMV14_RS21660	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CMV14_RS21670	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CMV14_RS21680	COG0730	response to heat
CMV14_RS21690	COG1309	transcriptional regulator
CMV14_RS21720	COG5002	protein histidine kinase activity
CMV14_RS21725	COG0704	Plays a role in the regulation of phosphate uptake
CMV14_RS21730	COG0745	RESPONSE REGULATOR receiver
CMV14_RS21745	COG1045	serine acetyltransferase
CMV14_RS21760	COG2239	Acts as a magnesium transporter
CMV14_RS21780	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CMV14_RS21790	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CMV14_RS21795	COG0739	heme binding
CMV14_RS21810	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CMV14_RS21825	COG0590	tRNA wobble adenosine to inosine editing
CMV14_RS21830	COG1253	flavin adenine dinucleotide binding
CMV14_RS21835	COG0776	regulation of translation
CMV14_RS21865	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS21880	COG0784	Response regulator, receiver
CMV14_RS21885	COG1396	sequence-specific DNA binding
CMV14_RS21885	COG3800	Transcriptional regulator
CMV14_RS21890	COG0667	Aldo Keto reductase
CMV14_RS21900	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CMV14_RS21905	COG2198	Histidine kinase
CMV14_RS21905	COG0643	Histidine kinase
CMV14_RS21910	COG2204	response regulator
CMV14_RS21940	COG0488	(ABC) transporter
CMV14_RS21945	COG0287	Prephenate dehydrogenase
CMV14_RS21945	COG1605	Chorismate mutase
CMV14_RS21950	COG0142	geranyltranstransferase activity
CMV14_RS21955	COG1643	Atp-dependent helicase
CMV14_RS21965	COG0442	prolyl-tRNA aminoacylation
CMV14_RS21975	COG1136	(ABC) transporter
CMV14_RS22020	COG1823	symporter activity
CMV14_RS22025	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CMV14_RS22035	COG2885	chlorophyll binding
CMV14_RS22045	COG5487	UPF0391 membrane protein
CMV14_RS22065	COG2365	Tyrosine phosphatase family
CMV14_RS22075	COG0433	COG0433 Predicted ATPase
CMV14_RS22100	COG0626	cystathionine gamma-synthase activity
CMV14_RS22105	COG2897	thiosulfate sulfurtransferase activity
CMV14_RS22110	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CMV14_RS22135	COG1054	Belongs to the UPF0176 family
CMV14_RS22155	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CMV14_RS22160	COG2835	tetraacyldisaccharide 4'-kinase activity
CMV14_RS22170	COG3118	belongs to the thioredoxin family
CMV14_RS22190	COG1475	DNA binding
CMV14_RS22260	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CMV14_RS22290	COG0419	ATPase involved in DNA repair
CMV14_RS22300	COG1104	cysteine desulfurase activity
CMV14_RS22315	COG5489	Protein of unknown function (DUF736)
CMV14_RS22360	COG0741	lytic transglycosylase activity
CMV14_RS22390	COG4962	Type ii secretion system protein e
CMV14_RS22405	COG3451	type IV secretory pathway VirB4
CMV14_RS22435	COG2948	multi-organism process
CMV14_RS22445	COG0583	DNA-binding transcription factor activity
CMV14_RS22450	COG1309	transcriptional regulator
CMV14_RS22480	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CMV14_RS22485	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CMV14_RS22500	COG3118	belongs to the thioredoxin family
CMV14_RS22525	COG0785	Cytochrome C biogenesis protein
CMV14_RS22530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CMV14_RS22540	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CMV14_RS22550	COG1595	DNA-templated transcription, initiation
CMV14_RS22590	COG3220	belongs to the UPF0276 family
CMV14_RS22605	COG1309	transcriptional regulator
CMV14_RS22635	COG4774	siderophore transport
CMV14_RS22645	COG4584	PFAM Integrase catalytic
CMV14_RS22665	COG0625	glutathione transferase activity
CMV14_RS22675	COG0464	growth
CMV14_RS22690	COG1595	DNA-templated transcription, initiation
CMV14_RS22725	COG0633	Ferredoxin
CMV14_RS22735	COG0842	Transport permease protein
CMV14_RS22740	COG1131	(ABC) transporter
CMV14_RS22755	COG0625	glutathione transferase activity
CMV14_RS22770	COG1970	mechanosensitive ion channel activity
CMV14_RS22775	COG1704	LemA family
CMV14_RS22780	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CMV14_RS22810	COG1595	DNA-templated transcription, initiation
CMV14_RS22825	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CMV14_RS22840	COG2840	Smr protein MutS2
CMV14_RS22855	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CMV14_RS22865	COG0180	Tryptophanyl-tRNA synthetase
CMV14_RS22870	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CMV14_RS22870	COG1754	DNA topoisomerase type I activity
CMV14_RS22875	COG0758	DNA mediated transformation
CMV14_RS22880	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CMV14_RS22885	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CMV14_RS22890	COG0156	8-amino-7-oxononanoate synthase activity
CMV14_RS22895	COG0840	transmembrane signaling receptor activity
CMV14_RS22920	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CMV14_RS22925	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CMV14_RS22940	COG1435	thymidine kinase activity
CMV14_RS22955	COG1185	polyribonucleotide nucleotidyltransferase activity
CMV14_RS22960	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CMV14_RS22965	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CMV14_RS22970	COG0753	catalase activity
CMV14_RS22990	COG0739	heme binding
CMV14_RS22995	COG1376	ErfK ybiS ycfS ynhG family protein
CMV14_RS23010	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CMV14_RS23015	COG2081	HI0933 family
CMV14_RS23020	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CMV14_RS23025	COG0513	Belongs to the DEAD box helicase family
CMV14_RS23040	COG1960	acyl-CoA dehydrogenase activity
CMV14_RS23045	COG1024	Enoyl-CoA hydratase
CMV14_RS23045	COG1250	3-hydroxyacyl-CoA dehydrogenase
CMV14_RS23050	COG0183	Belongs to the thiolase family
CMV14_RS23065	COG0318	PFAM AMP-dependent synthetase and ligase
CMV14_RS23110	COG0708	Exodeoxyribonuclease III
CMV14_RS23115	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CMV14_RS23125	COG0196	riboflavin kinase activity
CMV14_RS23130	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CMV14_RS23135	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CMV14_RS23145	COG0601	transmembrane transport
CMV14_RS23150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CMV14_RS23155	COG4172	Belongs to the ABC transporter superfamily
CMV14_RS23170	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CMV14_RS23175	COG0179	Fumarylacetoacetate (FAA) hydrolase
CMV14_RS23190	COG4191	Histidine kinase
CMV14_RS23190	COG0784	Response regulator, receiver
CMV14_RS23195	COG2207	Transcriptional regulator
CMV14_RS23200	COG2267	carboxylic ester hydrolase activity
CMV14_RS23205	COG4774	siderophore transport
CMV14_RS23210	COG2814	Major facilitator Superfamily
CMV14_RS23215	COG1058	Belongs to the CinA family
CMV14_RS23215	COG1546	Belongs to the CinA family
CMV14_RS23255	COG1530	ribonuclease E activity
CMV14_RS23260	COG0860	N-Acetylmuramoyl-L-alanine amidase
CMV14_RS23265	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CMV14_RS23295	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CMV14_RS23315	COG0504	CTP synthase activity
CMV14_RS23325	COG0149	triose-phosphate isomerase activity
CMV14_RS23335	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CMV14_RS23350	COG0330	HflC and HflK could
CMV14_RS23355	COG0330	HflC and HflK could
CMV14_RS23360	COG0489	protein tyrosine kinase activity
CMV14_RS23365	COG1832	CoA-binding protein
CMV14_RS23370	COG1218	3'(2'),5'-bisphosphate nucleotidase
CMV14_RS23375	COG0312	modulator of DNA gyrase
CMV14_RS23380	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CMV14_RS23420	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CMV14_RS23440	COG1215	transferase activity, transferring glycosyl groups
CMV14_RS23475	COG4957	zinc ion binding
CMV14_RS23495	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CMV14_RS23500	COG1702	phosphate starvation-inducible protein PhoH
CMV14_RS23505	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CMV14_RS23520	COG1253	flavin adenine dinucleotide binding
CMV14_RS23530	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CMV14_RS23535	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CMV14_RS23540	COG2084	Dehydrogenase
CMV14_RS23550	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
CMV14_RS23565	COG0646	methionine synthase
CMV14_RS23565	COG1410	methionine synthase
CMV14_RS23580	COG0640	Transcriptional regulator
CMV14_RS23585	COG2853	Lipoprotein
CMV14_RS23595	COG0671	phosphoesterase, PA-phosphatase related
CMV14_RS23640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CMV14_RS23655	COG0072	phenylalanine-tRNA ligase activity
CMV14_RS23660	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CMV14_RS23670	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CMV14_RS23675	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CMV14_RS23735	COG0789	Transcriptional regulator
CMV14_RS23740	COG2226	methyltransferase
CMV14_RS23750	COG0672	)-iron permease
CMV14_RS23755	COG0789	Transcriptional regulator
CMV14_RS23880	COG1230	cation diffusion facilitator family transporter
CMV14_RS23980	COG4227	nucleotidyltransferase activity
CMV14_RS24000	COG0798	PFAM Bile acid sodium symporter
CMV14_RS24005	COG4227	nucleotidyltransferase activity
CMV14_RS24015	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CMV14_RS24025	COG0798	PFAM Bile acid sodium symporter
CMV14_RS24030	COG2153	protein acetylation
CMV14_RS24095	COG1475	DNA binding
CMV14_RS24170	COG3505	Type IV secretory pathway VirD4
CMV14_RS24175	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
CMV14_RS24180	COG2948	multi-organism process
CMV14_RS24185	COG3504	Conjugal transfer protein
CMV14_RS24190	COG3736	Type IV secretory pathway, component VirB8
CMV14_RS24210	COG3451	type IV secretory pathway VirB4
CMV14_RS24240	COG3916	Acyl-homoserine-lactone synthase
CMV14_RS24250	COG2197	response regulator
CMV14_RS24270	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CMV14_RS24275	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CMV14_RS24280	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CMV14_RS24310	COG4584	PFAM Integrase catalytic
CMV14_RS24320	COG4774	siderophore transport
CMV14_RS24350	COG2132	Multicopper oxidase
CMV14_RS24370	COG4566	intracellular signal transduction
CMV14_RS24375	COG4191	Histidine kinase
CMV14_RS24390	COG2132	Multicopper oxidase
CMV14_RS24430	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CMV14_RS24485	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CMV14_RS24570	COG2267	carboxylic ester hydrolase activity
CMV14_RS24580	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CMV14_RS24590	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CMV14_RS24595	COG1127	ABC transporter
CMV14_RS24635	COG4644	lycopene metabolic process
CMV14_RS24670	COG0789	Transcriptional regulator
CMV14_RS24680	COG0672	)-iron permease
CMV14_RS24745	COG4644	lycopene metabolic process
CMV14_RS24780	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CMV14_RS24800	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CMV14_RS24845	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CMV14_RS24895	COG1012	belongs to the aldehyde dehydrogenase family
CMV14_RS24905	COG2132	Multicopper oxidase
CMV14_RS24925	COG3077	Addiction module antitoxin, RelB DinJ family
CMV14_RS24930	COG3041	Addiction module toxin RelE StbE family
CMV14_RS24960	COG1959	2 iron, 2 sulfur cluster binding
CMV14_RS24975	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CMV14_RS24975	COG1017	nitric oxide dioxygenase activity
CMV14_RS24995	COG3278	Belongs to the heme-copper respiratory oxidase family
CMV14_RS25010	COG2010	Cytochrome c
CMV14_RS25065	COG0629	single-stranded DNA binding
CMV14_RS25075	COG1309	transcriptional regulator
CMV14_RS25080	COG1028	Short-chain dehydrogenase reductase Sdr
CMV14_RS25095	COG4566	intracellular signal transduction
CMV14_RS25100	COG4191	Histidine kinase
CMV14_RS25115	COG2132	Multicopper oxidase
CMV14_RS25145	COG2264	protein methyltransferase activity
CMV14_RS25180	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CMV14_RS25195	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CMV14_RS25210	COG0356	it plays a direct role in the translocation of protons across the membrane
CMV14_RS25220	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CMV14_RS25220	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CMV14_RS25225	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CMV14_RS25235	COG4716	Myosin-crossreactive antigen
CMV14_RS25255	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CMV14_RS25260	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CMV14_RS25285	COG2963	transposase activity
CMV14_RS25290	COG3436	PFAM IS66 Orf2 family protein
CMV14_RS25295	COG4372	Transposase
CMV14_RS25455	COG2814	Major facilitator Superfamily
CMV14_RS25500	COG0587	DNA-directed DNA polymerase activity
CMV14_RS25635	COG0629	single-stranded DNA binding
CMV14_RS25730	COG1475	DNA binding
CMV14_RS25765	COG0798	PFAM Bile acid sodium symporter
CMV14_RS25785	COG4227	nucleotidyltransferase activity
CMV14_RS25890	COG4227	nucleotidyltransferase activity
CMV14_RS25905	COG3012	SEC-C Motif Domain Protein
CMV14_RS25965	COG3702	type iv secretory pathway
CMV14_RS25970	COG3451	type IV secretory pathway VirB4
CMV14_RS25995	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
CMV14_RS26030	COG1475	DNA binding
CMV14_RS26035	COG1192	Involved in chromosome partitioning
CMV14_RS26050	COG0629	single-stranded DNA binding
CMV14_RS26060	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CMV14_RS26070	COG1396	sequence-specific DNA binding
CMV14_RS26165	COG1192	Involved in chromosome partitioning
CMV14_RS26215	COG2814	Major facilitator Superfamily
CMV14_RS26245	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs