locus-tag	class	description
RSPH17029_RS00030	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
RSPH17029_RS00070	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
RSPH17029_RS00090	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
RSPH17029_RS00095	COG0560	Phosphoserine phosphatase
RSPH17029_RS00100	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
RSPH17029_RS00105	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RSPH17029_RS00115	COG0183	Belongs to the thiolase family
RSPH17029_RS00120	COG4953	penicillin-binding protein 1C
RSPH17029_RS00125	COG2373	Large extracellular alpha-helical protein
RSPH17029_RS00130	COG5002	protein histidine kinase activity
RSPH17029_RS00130	COG0784	Response regulator, receiver
RSPH17029_RS00130	COG2205	protein histidine kinase activity
RSPH17029_RS00140	COG0514	ATP-dependent DNA helicase (RecQ)
RSPH17029_RS00160	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
RSPH17029_RS00170	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
RSPH17029_RS00180	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
RSPH17029_RS00185	COG1335	isochorismatase
RSPH17029_RS00190	COG1028	Short-chain dehydrogenase reductase Sdr
RSPH17029_RS00195	COG3734	2-keto-3-deoxy-galactonokinase
RSPH17029_RS00200	COG0366	Alpha amylase catalytic
RSPH17029_RS00205	COG2271	Major facilitator Superfamily
RSPH17029_RS00215	COG0438	transferase activity, transferring glycosyl groups
RSPH17029_RS00230	COG0288	reversible hydration of carbon dioxide
RSPH17029_RS00240	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
RSPH17029_RS00245	COG0791	NLP P60 protein
RSPH17029_RS00250	COG3214	Protein conserved in bacteria
RSPH17029_RS00275	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
RSPH17029_RS00305	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
RSPH17029_RS00325	COG0625	glutathione transferase activity
RSPH17029_RS00350	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
RSPH17029_RS00370	COG0284	orotidine-5'-phosphate decarboxylase activity
RSPH17029_RS00375	COG1940	carbohydrate kinase activity
RSPH17029_RS00385	COG0542	response to heat
RSPH17029_RS00390	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
RSPH17029_RS00395	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
RSPH17029_RS00435	COG0662	Cupin 2, conserved barrel domain protein
RSPH17029_RS00440	COG0604	alcohol dehydrogenase
RSPH17029_RS00445	COG1309	transcriptional regulator
RSPH17029_RS00450	COG0488	(ABC) transporter
RSPH17029_RS00455	COG1120	ATPase activity
RSPH17029_RS00465	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RSPH17029_RS00470	COG4774	siderophore transport
RSPH17029_RS00475	COG1940	carbohydrate kinase activity
RSPH17029_RS00485	COG1175	transmembrane transport
RSPH17029_RS00490	COG0395	ABC-type sugar transport system, permease component
RSPH17029_RS00500	COG2971	BadF BadG BcrA BcrD
RSPH17029_RS00515	COG1349	DNA-binding transcription factor activity
RSPH17029_RS00530	COG0601	transmembrane transport
RSPH17029_RS00545	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RSPH17029_RS00585	COG1519	Transferase
RSPH17029_RS00610	COG1194	a g-specific adenine glycosylase
RSPH17029_RS00650	COG0019	diaminopimelate decarboxylase activity
RSPH17029_RS00670	COG4172	Belongs to the ABC transporter superfamily
RSPH17029_RS00675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RSPH17029_RS00680	COG0601	transmembrane transport
RSPH17029_RS00685	COG4166	transmembrane transport
RSPH17029_RS00705	COG1309	transcriptional regulator
RSPH17029_RS00710	COG5507	3-demethylubiquinone-9 3-methyltransferase
RSPH17029_RS00720	COG3118	belongs to the thioredoxin family
RSPH17029_RS00735	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RSPH17029_RS00740	COG0154	amidase activity
RSPH17029_RS00745	COG0436	Aminotransferase
RSPH17029_RS00750	COG1674	ftsk spoiiie
RSPH17029_RS00770	COG0405	Gamma-glutamyltransferase
RSPH17029_RS00785	COG1956	GAF domain-containing protein
RSPH17029_RS00800	COG0564	pseudouridine synthase activity
RSPH17029_RS00840	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
RSPH17029_RS00855	COG0133	tryptophan synthase activity
RSPH17029_RS00870	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
RSPH17029_RS00880	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
RSPH17029_RS00885	COG1999	signal sequence binding
RSPH17029_RS00890	COG2205	protein histidine kinase activity
RSPH17029_RS00895	COG2205	protein histidine kinase activity
RSPH17029_RS00905	COG3178	'Phosphotransferase
RSPH17029_RS00910	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
RSPH17029_RS00915	COG2887	Belongs to the helicase family. UvrD subfamily
RSPH17029_RS00920	COG1074	ATP-dependent DNA helicase activity
RSPH17029_RS00945	COG1696	Membrane protein involved in D-alanine export
RSPH17029_RS00975	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
RSPH17029_RS00980	COG0463	Glycosyl transferase, family 2
RSPH17029_RS00990	COG0577	efflux transmembrane transporter activity
RSPH17029_RS00995	COG1136	(ABC) transporter
RSPH17029_RS01035	COG1414	Transcriptional regulator
RSPH17029_RS01045	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
RSPH17029_RS01050	COG3257	ureidoglycine aminohydrolase activity
RSPH17029_RS01060	COG2351	hydroxyisourate hydrolase activity
RSPH17029_RS01075	COG0538	isocitrate dehydrogenase activity
RSPH17029_RS01080	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
RSPH17029_RS01085	COG0318	PFAM AMP-dependent synthetase and ligase
RSPH17029_RS01090	COG0179	Fumarylacetoacetate (FAA) hydrolase
RSPH17029_RS01095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RSPH17029_RS01100	COG0628	permease
RSPH17029_RS01120	COG0174	glutamine synthetase
RSPH17029_RS01125	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
RSPH17029_RS01130	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
RSPH17029_RS01155	COG3038	cytochrome b561
RSPH17029_RS01160	COG0529	Catalyzes the synthesis of activated sulfate
RSPH17029_RS01160	COG2046	Belongs to the sulfate adenylyltransferase family
RSPH17029_RS01165	COG0492	ferredoxin-NADP+ reductase activity
RSPH17029_RS01170	COG1522	sequence-specific DNA binding
RSPH17029_RS01175	COG1496	oxidoreductase activity
RSPH17029_RS01200	COG0745	RESPONSE REGULATOR receiver
RSPH17029_RS01210	COG0835	chemotaxis
RSPH17029_RS01215	COG0835	chemotaxis
RSPH17029_RS01220	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
RSPH17029_RS01225	COG2201	protein-glutamate methylesterase activity
RSPH17029_RS01235	COG0435	Glutathione S-transferase
RSPH17029_RS01240	COG2204	response regulator
RSPH17029_RS01255	COG0281	malic enzyme
RSPH17029_RS01255	COG0280	phosphate acetyltransferase
RSPH17029_RS01260	COG0295	cytidine deaminase activity
RSPH17029_RS01265	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
RSPH17029_RS01270	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
RSPH17029_RS01275	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
RSPH17029_RS01280	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
RSPH17029_RS01310	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
RSPH17029_RS01320	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
RSPH17029_RS01325	COG2186	Transcriptional regulator
RSPH17029_RS01330	COG1802	Transcriptional regulator
RSPH17029_RS01335	COG1063	alcohol dehydrogenase
RSPH17029_RS01340	COG0246	Mannitol dehydrogenase
RSPH17029_RS01345	COG2721	sulfolactate sulfo-lyase activity
RSPH17029_RS01350	COG4191	Histidine kinase
RSPH17029_RS01355	COG2204	response regulator
RSPH17029_RS01360	COG2358	TRAP transporter, solute receptor (TAXI family
RSPH17029_RS01485	COG4974	Belongs to the 'phage' integrase family
RSPH17029_RS01505	COG1609	Transcriptional regulator
RSPH17029_RS01530	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
RSPH17029_RS01540	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
RSPH17029_RS01560	COG0681	Belongs to the peptidase S26 family
RSPH17029_RS01570	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
RSPH17029_RS01595	COG0745	RESPONSE REGULATOR receiver
RSPH17029_RS01600	COG2205	protein histidine kinase activity
RSPH17029_RS01620	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
RSPH17029_RS01630	COG1250	3-hydroxyacyl-CoA dehydrogenase
RSPH17029_RS01650	COG2096	Adenosyltransferase
RSPH17029_RS01660	COG0300	oxidoreductase activity
RSPH17029_RS01670	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
RSPH17029_RS01715	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
RSPH17029_RS01735	COG0697	spore germination
RSPH17029_RS01790	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
RSPH17029_RS01810	COG0697	spore germination
RSPH17029_RS01840	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
RSPH17029_RS01880	COG0255	Belongs to the universal ribosomal protein uL29 family
RSPH17029_RS01940	COG0201	protein transport
RSPH17029_RS01945	COG0563	adenylate kinase activity
RSPH17029_RS01975	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RSPH17029_RS01980	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
RSPH17029_RS01990	COG0564	pseudouridine synthase activity
RSPH17029_RS02000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RSPH17029_RS02005	COG4597	amino acid ABC transporter
RSPH17029_RS02010	COG0765	amino acid transport
RSPH17029_RS02015	COG1126	abc transporter atp-binding protein
RSPH17029_RS02055	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RSPH17029_RS02070	COG0072	phenylalanine-tRNA ligase activity
RSPH17029_RS02070	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RSPH17029_RS02100	COG0469	pyruvate kinase activity
RSPH17029_RS02115	COG4948	Mandelate Racemase Muconate Lactonizing
RSPH17029_RS02145	COG2133	pyrroloquinoline quinone binding
RSPH17029_RS02200	COG1609	Transcriptional regulator
RSPH17029_RS02205	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
RSPH17029_RS02205	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
RSPH17029_RS02210	COG1105	Belongs to the carbohydrate kinase PfkB family
RSPH17029_RS02215	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RSPH17029_RS02215	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RSPH17029_RS02225	COG0789	Transcriptional regulator
RSPH17029_RS02230	COG2217	Heavy metal translocating P-type atpase
RSPH17029_RS02235	COG0629	single-stranded DNA binding
RSPH17029_RS02240	COG0741	lytic transglycosylase activity
RSPH17029_RS02245	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
RSPH17029_RS02250	COG2032	superoxide dismutase activity
RSPH17029_RS02255	COG1862	Preprotein translocase
RSPH17029_RS02260	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RSPH17029_RS02265	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RSPH17029_RS02270	COG3737	Protein of unknown function (DUF498/DUF598)
RSPH17029_RS02275	COG4133	protoheme IX ABC transporter activity
RSPH17029_RS02280	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RSPH17029_RS02285	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RSPH17029_RS02295	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RSPH17029_RS02300	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
RSPH17029_RS02315	COG0180	Tryptophanyl-tRNA synthetase
RSPH17029_RS02325	COG0728	peptidoglycan biosynthetic process
RSPH17029_RS02330	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
RSPH17029_RS02340	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
RSPH17029_RS02350	COG0189	ligase activity
RSPH17029_RS02355	COG0606	chelatase, subunit chli
RSPH17029_RS02370	COG1918	ferrous iron import across plasma membrane
RSPH17029_RS02380	COG3685	Protein conserved in bacteria
RSPH17029_RS02385	COG0243	molybdopterin cofactor binding
RSPH17029_RS02390	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
RSPH17029_RS02395	COG0521	Mo-molybdopterin cofactor biosynthetic process
RSPH17029_RS02405	COG0312	modulator of DNA gyrase
RSPH17029_RS02440	COG0612	Peptidase, M16
RSPH17029_RS02465	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
RSPH17029_RS02485	COG2917	probably involved in intracellular septation
RSPH17029_RS02495	COG0552	protein localization to endoplasmic reticulum
RSPH17029_RS02515	COG0151	Belongs to the GarS family
RSPH17029_RS02520	COG0469	pyruvate kinase activity
RSPH17029_RS02525	COG0527	aspartate kinase activity
RSPH17029_RS02545	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
RSPH17029_RS02550	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
RSPH17029_RS02560	COG0752	glycyl-tRNA synthetase alpha subunit
RSPH17029_RS02575	COG0574	Belongs to the PEP-utilizing enzyme family
RSPH17029_RS02575	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
RSPH17029_RS02585	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
RSPH17029_RS02610	COG1522	sequence-specific DNA binding
RSPH17029_RS02615	COG1522	sequence-specific DNA binding
RSPH17029_RS02640	COG1802	Transcriptional regulator
RSPH17029_RS02655	COG0505	Belongs to the CarA family
RSPH17029_RS02690	COG3842	ATPase activity
RSPH17029_RS02700	COG1176	ABC-type spermidine putrescine transport system, permease component I
RSPH17029_RS02705	COG1177	transmembrane transport
RSPH17029_RS02720	COG0670	Belongs to the BI1 family
RSPH17029_RS02730	COG0583	DNA-binding transcription factor activity
RSPH17029_RS02735	COG3321	synthase
RSPH17029_RS02735	COG0604	alcohol dehydrogenase
RSPH17029_RS02735	COG1028	Short-chain dehydrogenase reductase Sdr
RSPH17029_RS02750	COG3773	Cell wall hydrolase
RSPH17029_RS02755	COG0668	transmembrane transport
RSPH17029_RS02760	COG0402	S-adenosylhomocysteine deaminase activity
RSPH17029_RS02765	COG2239	Acts as a magnesium transporter
RSPH17029_RS02770	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
RSPH17029_RS02820	COG4964	Belongs to the GSP D family
RSPH17029_RS02840	COG0741	lytic transglycosylase activity
RSPH17029_RS02865	COG0583	DNA-binding transcription factor activity
RSPH17029_RS02895	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
RSPH17029_RS02900	COG2258	MOSC domain
RSPH17029_RS02920	COG1268	BioY protein
RSPH17029_RS02930	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
RSPH17029_RS02935	COG0730	response to heat
RSPH17029_RS02940	COG0305	Participates in initiation and elongation during chromosome replication
RSPH17029_RS02950	COG0418	dihydroorotase activity
RSPH17029_RS02955	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
RSPH17029_RS02975	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
RSPH17029_RS02985	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
RSPH17029_RS03005	COG0175	sulfate reduction
RSPH17029_RS03010	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RSPH17029_RS03020	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
RSPH17029_RS03020	COG1648	precorrin-2 dehydrogenase activity
RSPH17029_RS03025	COG1522	sequence-specific DNA binding
RSPH17029_RS03035	COG0149	triose-phosphate isomerase activity
RSPH17029_RS03045	COG2151	metal-sulfur cluster biosynthetic enzyme
RSPH17029_RS03060	COG1278	Cold shock
RSPH17029_RS03065	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RSPH17029_RS03090	COG3436	PFAM IS66 Orf2 family protein
RSPH17029_RS03275	COG0740	serine-type endopeptidase activity
RSPH17029_RS03320	COG1475	DNA binding
RSPH17029_RS03465	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
RSPH17029_RS03470	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
RSPH17029_RS03480	COG2166	iron-sulfur cluster assembly
RSPH17029_RS03490	COG0006	proline dipeptidase activity
RSPH17029_RS03515	COG0484	heat shock protein binding
RSPH17029_RS03525	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
RSPH17029_RS03530	COG0415	Belongs to the DNA photolyase family
RSPH17029_RS03535	COG0308	aminopeptidase N
RSPH17029_RS03545	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
RSPH17029_RS03610	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
RSPH17029_RS03615	COG0303	'Molybdopterin
RSPH17029_RS03645	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
RSPH17029_RS03665	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
RSPH17029_RS03680	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
RSPH17029_RS03690	COG1643	Atp-dependent helicase
RSPH17029_RS03700	COG1703	isobutyryl-CoA mutase activity
RSPH17029_RS03740	COG1858	cytochrome C peroxidase
RSPH17029_RS03755	COG1278	Cold shock
RSPH17029_RS03765	COG0583	DNA-binding transcription factor activity
RSPH17029_RS03780	COG3920	Histidine kinase
RSPH17029_RS03780	COG2202	Pas domain
RSPH17029_RS03865	COG0556	nucleotide-excision repair
RSPH17029_RS03905	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
RSPH17029_RS03910	COG0210	DNA helicase
RSPH17029_RS03915	COG3135	benzoate transporter
RSPH17029_RS03920	COG0489	protein tyrosine kinase activity
RSPH17029_RS03945	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
RSPH17029_RS04010	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
RSPH17029_RS04015	COG0849	cell division
RSPH17029_RS04020	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
RSPH17029_RS04025	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
RSPH17029_RS04030	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
RSPH17029_RS04045	COG0277	FAD linked oxidase domain protein
RSPH17029_RS04055	COG5012	cobalamin binding
RSPH17029_RS04065	COG1410	methionine synthase
RSPH17029_RS04065	COG0646	methionine synthase
RSPH17029_RS04075	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
RSPH17029_RS04080	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
RSPH17029_RS04085	COG0047	phosphoribosylformylglycinamidine synthase activity
RSPH17029_RS04095	COG2204	response regulator
RSPH17029_RS04100	COG1530	ribonuclease E activity
RSPH17029_RS04110	COG0785	Cytochrome C biogenesis protein
RSPH17029_RS04130	COG0114	fumarate hydratase activity
RSPH17029_RS04145	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
RSPH17029_RS04150	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
RSPH17029_RS04155	COG0415	Belongs to the DNA photolyase family
RSPH17029_RS04160	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
RSPH17029_RS04170	COG0494	nUDIX hydrolase
RSPH17029_RS04180	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
RSPH17029_RS04180	COG3264	Mechanosensitive ion channel
RSPH17029_RS04185	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
RSPH17029_RS04215	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
RSPH17029_RS04220	COG1177	transmembrane transport
RSPH17029_RS04235	COG3842	ATPase activity
RSPH17029_RS04240	COG1028	Short-chain dehydrogenase reductase Sdr
RSPH17029_RS04245	COG0671	phosphoesterase, PA-phosphatase related
RSPH17029_RS04260	COG1522	sequence-specific DNA binding
RSPH17029_RS04280	COG0483	inositol monophosphate 1-phosphatase activity
RSPH17029_RS04285	COG0306	phosphate transporter
RSPH17029_RS04290	COG0583	DNA-binding transcription factor activity
RSPH17029_RS04300	COG1268	BioY protein
RSPH17029_RS04305	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
RSPH17029_RS04310	COG1122	ATPase activity
RSPH17029_RS04315	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
RSPH17029_RS04320	COG0758	DNA mediated transformation
RSPH17029_RS04325	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
RSPH17029_RS04325	COG1754	DNA topoisomerase type I activity
RSPH17029_RS04330	COG4175	Glycine betaine
RSPH17029_RS04345	COG1309	transcriptional regulator
RSPH17029_RS04355	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
RSPH17029_RS04365	COG3800	Transcriptional regulator
RSPH17029_RS04365	COG1396	sequence-specific DNA binding
RSPH17029_RS04380	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
RSPH17029_RS04405	COG4770	biotin carboxylase activity
RSPH17029_RS04415	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
RSPH17029_RS04415	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
RSPH17029_RS04420	COG0404	The glycine cleavage system catalyzes the degradation of glycine
RSPH17029_RS04425	COG0509	glycine decarboxylation via glycine cleavage system
RSPH17029_RS04435	COG1250	3-hydroxyacyl-CoA dehydrogenase
RSPH17029_RS04435	COG1024	Enoyl-CoA hydratase
RSPH17029_RS04440	COG0183	Belongs to the thiolase family
RSPH17029_RS04450	COG1960	acyl-CoA dehydrogenase activity
RSPH17029_RS04475	COG0534	Mate efflux family protein
RSPH17029_RS04485	COG0730	response to heat
RSPH17029_RS04490	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
RSPH17029_RS04495	COG1079	Belongs to the binding-protein-dependent transport system permease family
RSPH17029_RS04500	COG4603	Belongs to the binding-protein-dependent transport system permease family
RSPH17029_RS04505	COG3845	ABC transporter
RSPH17029_RS04510	COG1744	ABC transporter substrate-binding protein PnrA-like
RSPH17029_RS04520	COG1214	PFAM Peptidase M22, glycoprotease
RSPH17029_RS04525	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
RSPH17029_RS04540	COG2514	catechol 2,3-dioxygenase activity
RSPH17029_RS04545	COG1376	ErfK ybiS ycfS ynhG family protein
RSPH17029_RS04560	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
RSPH17029_RS04565	COG3042	response to heat
RSPH17029_RS04590	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
RSPH17029_RS04615	COG1573	uracil-dna glycosylase
RSPH17029_RS04640	COG2814	Major facilitator Superfamily
RSPH17029_RS04655	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RSPH17029_RS04660	COG1832	CoA-binding protein
RSPH17029_RS04685	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
RSPH17029_RS04695	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
RSPH17029_RS04725	COG1132	(ABC) transporter
RSPH17029_RS04730	COG0318	PFAM AMP-dependent synthetase and ligase
RSPH17029_RS04745	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
RSPH17029_RS04750	COG1238	metal cluster binding
RSPH17029_RS04790	COG1187	pseudouridine synthase activity
RSPH17029_RS04795	COG0590	tRNA wobble adenosine to inosine editing
RSPH17029_RS04825	COG3023	N-Acetylmuramoyl-L-alanine amidase
RSPH17029_RS04850	COG0559	Belongs to the binding-protein-dependent transport system permease family
RSPH17029_RS04860	COG1022	Amp-dependent synthetase and ligase
RSPH17029_RS04900	COG0287	Prephenate dehydrogenase
RSPH17029_RS04915	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
RSPH17029_RS04975	COG0355	proton-transporting ATP synthase activity, rotational mechanism
RSPH17029_RS04990	COG2983	Belongs to the UPF0260 family
RSPH17029_RS04995	COG0196	riboflavin kinase activity
RSPH17029_RS05000	COG2030	dehydratase
RSPH17029_RS05010	COG1227	inorganic diphosphatase activity
RSPH17029_RS05040	COG0656	L-ascorbic acid biosynthetic process
RSPH17029_RS05050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RSPH17029_RS05065	COG0174	glutamine synthetase
RSPH17029_RS05070	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
RSPH17029_RS05095	COG0772	Belongs to the SEDS family
RSPH17029_RS05100	COG0768	penicillin binding
RSPH17029_RS05125	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RSPH17029_RS05150	COG0655	NAD(P)H dehydrogenase (quinone) activity
RSPH17029_RS05195	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
RSPH17029_RS05220	COG2188	Transcriptional regulator
RSPH17029_RS05225	COG1028	Short-chain dehydrogenase reductase Sdr
RSPH17029_RS05230	COG0235	Class ii aldolase
RSPH17029_RS05240	COG1129	ABC transporter
RSPH17029_RS05245	COG1172	Belongs to the binding-protein-dependent transport system permease family
RSPH17029_RS05250	COG1172	Belongs to the binding-protein-dependent transport system permease family
RSPH17029_RS05260	COG1028	Short-chain dehydrogenase reductase Sdr
RSPH17029_RS05290	COG0156	8-amino-7-oxononanoate synthase activity
RSPH17029_RS05295	COG1063	alcohol dehydrogenase
RSPH17029_RS05300	COG2124	cytochrome p450
RSPH17029_RS05310	COG0753	catalase activity
RSPH17029_RS05320	COG2094	Belongs to the DNA glycosylase MPG family
RSPH17029_RS05375	COG0123	including yeast histone deacetylase and acetoin utilization protein
RSPH17029_RS05405	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
RSPH17029_RS05410	COG1177	transmembrane transport
RSPH17029_RS05420	COG3842	ATPase activity
RSPH17029_RS05430	COG4206	TonB-dependent receptor
RSPH17029_RS05440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RSPH17029_RS05445	COG1120	ATPase activity
RSPH17029_RS05455	COG0784	Response regulator, receiver
RSPH17029_RS05455	COG5002	protein histidine kinase activity
RSPH17029_RS05465	COG0564	pseudouridine synthase activity
RSPH17029_RS05485	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
RSPH17029_RS05485	COG1793	dna ligase
RSPH17029_RS05495	COG2308	Evidence 4 Homologs of previously reported genes of
RSPH17029_RS05540	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
RSPH17029_RS05545	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
RSPH17029_RS05550	COG1329	Transcriptional regulator
RSPH17029_RS05555	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
RSPH17029_RS05575	COG2968	Membrane
RSPH17029_RS05580	COG2873	o-acetylhomoserine
RSPH17029_RS05590	COG0745	RESPONSE REGULATOR receiver
RSPH17029_RS05595	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
RSPH17029_RS05610	COG0745	RESPONSE REGULATOR receiver
RSPH17029_RS05625	COG0840	transmembrane signaling receptor activity
RSPH17029_RS05635	COG0840	transmembrane signaling receptor activity
RSPH17029_RS05640	COG0745	RESPONSE REGULATOR receiver
RSPH17029_RS05650	COG0366	Alpha amylase catalytic
RSPH17029_RS05670	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
RSPH17029_RS05685	COG4221	oxidoreductase activity
RSPH17029_RS05690	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
RSPH17029_RS05710	COG1127	ABC transporter
RSPH17029_RS05735	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
RSPH17029_RS05740	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
RSPH17029_RS05755	COG4695	Portal protein
RSPH17029_RS05835	COG0508	dehydrogenase complex catalyzes the overall conversion of
RSPH17029_RS05840	COG0508	dehydrogenase complex catalyzes the overall conversion of
RSPH17029_RS05840	COG0022	dehydrogenase e1 component
RSPH17029_RS05845	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
RSPH17029_RS05850	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
RSPH17029_RS05855	COG1830	Aldolase
RSPH17029_RS05880	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
RSPH17029_RS05895	COG0697	spore germination
RSPH17029_RS05905	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RSPH17029_RS05915	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
RSPH17029_RS05920	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
RSPH17029_RS05925	COG0546	phosphoglycolate phosphatase activity
RSPH17029_RS05935	COG1960	acyl-CoA dehydrogenase activity
RSPH17029_RS05940	COG3047	cAMP biosynthetic process
RSPH17029_RS05945	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
RSPH17029_RS05950	COG4770	biotin carboxylase activity
RSPH17029_RS05960	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
RSPH17029_RS05980	COG0649	NAD binding
RSPH17029_RS06015	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
RSPH17029_RS06050	COG1007	ATP synthesis coupled electron transport
RSPH17029_RS06070	COG0513	Belongs to the DEAD box helicase family
RSPH17029_RS06080	COG1028	Short-chain dehydrogenase reductase Sdr
RSPH17029_RS06085	COG3842	ATPase activity
RSPH17029_RS06090	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
RSPH17029_RS06100	COG0805	protein transport
RSPH17029_RS06110	COG0739	heme binding
RSPH17029_RS06110	COG1388	LysM domain
RSPH17029_RS06140	COG2273	Hydrolase Family 16
RSPH17029_RS06145	COG1215	transferase activity, transferring glycosyl groups
RSPH17029_RS06150	COG1215	transferase activity, transferring glycosyl groups
RSPH17029_RS06180	COG1132	(ABC) transporter
RSPH17029_RS06190	COG3206	protein involved in exopolysaccharide biosynthesis
RSPH17029_RS06190	COG0489	protein tyrosine kinase activity
RSPH17029_RS06200	COG1215	transferase activity, transferring glycosyl groups
RSPH17029_RS06205	COG0438	transferase activity, transferring glycosyl groups
RSPH17029_RS06215	COG1091	dTDP-4-dehydrorhamnose reductase activity
RSPH17029_RS06230	COG0693	protein deglycase activity
RSPH17029_RS06235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RSPH17029_RS06255	COG3791	Glutathione-dependent formaldehyde-activating
RSPH17029_RS06260	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
RSPH17029_RS06280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RSPH17029_RS06310	COG1131	(ABC) transporter
RSPH17029_RS06345	COG2205	protein histidine kinase activity
RSPH17029_RS06345	COG0784	Response regulator, receiver
RSPH17029_RS06345	COG2198	Histidine kinase
RSPH17029_RS06370	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RSPH17029_RS06375	COG0745	RESPONSE REGULATOR receiver
RSPH17029_RS06385	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
RSPH17029_RS06390	COG0581	inorganic phosphate transmembrane transporter activity
RSPH17029_RS06395	COG0573	inorganic phosphate transmembrane transporter activity
RSPH17029_RS06425	COG0717	Belongs to the dCTP deaminase family
RSPH17029_RS06470	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
RSPH17029_RS06490	COG0745	RESPONSE REGULATOR receiver
RSPH17029_RS06500	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
RSPH17029_RS06515	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
RSPH17029_RS06525	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
RSPH17029_RS06530	COG5425	PFAM Usg family protein
RSPH17029_RS06540	COG1138	Cytochrome C-type biogenesis protein
RSPH17029_RS06545	COG3088	subunit of a heme lyase
RSPH17029_RS06550	COG1024	Enoyl-CoA hydratase
RSPH17029_RS06555	COG0440	acetolactate synthase activity
RSPH17029_RS06560	COG0028	Belongs to the TPP enzyme family
RSPH17029_RS06590	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
RSPH17029_RS06600	COG0800	Aldolase
RSPH17029_RS06605	COG0129	dihydroxy-acid dehydratase activity
RSPH17029_RS06655	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RSPH17029_RS06680	COG1295	ribonuclease BN
RSPH17029_RS06685	COG1454	alcohol dehydrogenase
RSPH17029_RS06705	COG0395	ABC-type sugar transport system, permease component
RSPH17029_RS06715	COG3842	ATPase activity
RSPH17029_RS06720	COG3842	ATPase activity
RSPH17029_RS06790	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
RSPH17029_RS06810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RSPH17029_RS06825	COG0446	pyridine nucleotide-disulphide oxidoreductase
RSPH17029_RS06825	COG0404	The glycine cleavage system catalyzes the degradation of glycine
RSPH17029_RS06835	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
RSPH17029_RS06835	COG2755	lipolytic protein G-D-S-L family
RSPH17029_RS06845	COG1611	Belongs to the LOG family
RSPH17029_RS06855	COG5265	(ABC) transporter
RSPH17029_RS06880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RSPH17029_RS06885	COG0601	transmembrane transport
RSPH17029_RS06890	COG4166	transmembrane transport
RSPH17029_RS06910	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
RSPH17029_RS06915	COG0575	Belongs to the CDS family
RSPH17029_RS06925	COG0750	zinc metalloprotease
RSPH17029_RS06930	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
RSPH17029_RS06945	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
RSPH17029_RS06950	COG3494	Protein of unknown function (DUF1009)
RSPH17029_RS06955	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
RSPH17029_RS06960	COG0488	(ABC) transporter
RSPH17029_RS06990	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RSPH17029_RS07005	COG2814	Major facilitator Superfamily
RSPH17029_RS07010	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
RSPH17029_RS07035	COG0431	NADPH-dependent FMN reductase
RSPH17029_RS07045	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
RSPH17029_RS07060	COG0251	oxidation-reduction process
RSPH17029_RS07065	COG2897	thiosulfate sulfurtransferase activity
RSPH17029_RS07070	COG2391	methyltransferase activity
RSPH17029_RS07100	COG0438	transferase activity, transferring glycosyl groups
RSPH17029_RS07135	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
RSPH17029_RS07145	COG0248	Ppx GppA phosphatase
RSPH17029_RS07155	COG3108	Peptidase M15
RSPH17029_RS07165	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
RSPH17029_RS07185	COG0753	catalase activity
RSPH17029_RS07210	COG2010	Cytochrome c
RSPH17029_RS07215	COG3909	cytochrome
RSPH17029_RS07220	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
RSPH17029_RS07225	COG2867	negative regulation of translational initiation
RSPH17029_RS07255	COG2313	pseudouridylate synthase activity
RSPH17029_RS07260	COG1028	Short-chain dehydrogenase reductase Sdr
RSPH17029_RS07265	COG4166	transmembrane transport
RSPH17029_RS07295	COG2814	Major facilitator Superfamily
RSPH17029_RS07300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
RSPH17029_RS07320	COG2084	Dehydrogenase
RSPH17029_RS07330	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
RSPH17029_RS07345	COG0569	domain protein
RSPH17029_RS07350	COG2204	response regulator
RSPH17029_RS07355	COG5000	phosphorelay sensor kinase activity
RSPH17029_RS07360	COG2204	response regulator
RSPH17029_RS07365	COG3852	Histidine kinase
RSPH17029_RS07370	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
RSPH17029_RS07390	COG1546	Belongs to the CinA family
RSPH17029_RS07390	COG1058	Belongs to the CinA family
RSPH17029_RS07395	COG2081	HI0933 family
RSPH17029_RS07445	COG2099	Precorrin-6x reductase
RSPH17029_RS07460	COG2875	Belongs to the precorrin methyltransferase family
RSPH17029_RS07465	COG1648	precorrin-2 dehydrogenase activity
RSPH17029_RS07465	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
RSPH17029_RS07480	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
RSPH17029_RS07490	COG4974	Belongs to the 'phage' integrase family
RSPH17029_RS07495	COG4536	flavin adenine dinucleotide binding
RSPH17029_RS07510	COG5598	trimethylamine methyltransferase
RSPH17029_RS07525	COG1127	ABC transporter
RSPH17029_RS07530	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
RSPH17029_RS07555	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
RSPH17029_RS07560	COG1902	pentaerythritol trinitrate reductase activity
RSPH17029_RS07570	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RSPH17029_RS07600	COG0459	protein refolding
RSPH17029_RS07605	COG0489	protein tyrosine kinase activity
RSPH17029_RS07605	COG2151	metal-sulfur cluster biosynthetic enzyme
RSPH17029_RS07625	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RSPH17029_RS07660	COG0516	GMP reductase activity
RSPH17029_RS07660	COG0517	IMP dehydrogenase activity
RSPH17029_RS07670	COG3842	ATPase activity
RSPH17029_RS07675	COG0395	ABC-type sugar transport system, permease component
RSPH17029_RS07680	COG1175	transmembrane transport
RSPH17029_RS07685	COG1653	transport
RSPH17029_RS07690	COG2723	6-phospho-beta-galactosidase activity
RSPH17029_RS07695	COG0837	glucose binding
RSPH17029_RS07720	COG2205	protein histidine kinase activity
RSPH17029_RS07720	COG2198	Histidine kinase
RSPH17029_RS07720	COG0784	Response regulator, receiver
RSPH17029_RS07735	COG0033	Phosphoglucomutase
RSPH17029_RS07745	COG0297	glycogen (starch) synthase activity
RSPH17029_RS07755	COG0058	SHG alpha-glucan phosphorylase activity
RSPH17029_RS07760	COG1959	2 iron, 2 sulfur cluster binding
RSPH17029_RS07785	COG0488	(ABC) transporter
RSPH17029_RS07790	COG2095	MarC family integral membrane protein
RSPH17029_RS07795	COG3577	Aspartyl protease
RSPH17029_RS07805	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
RSPH17029_RS07810	COG0795	lipopolysaccharide-transporting ATPase activity
RSPH17029_RS07825	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
RSPH17029_RS07830	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
RSPH17029_RS07845	COG2890	protein-(glutamine-N5) methyltransferase activity
RSPH17029_RS07860	COG0010	Belongs to the arginase family
RSPH17029_RS07865	COG1473	amidohydrolase
RSPH17029_RS07870	COG3956	TIGRFAM MazG family protein
RSPH17029_RS07875	COG1840	ABC-type Fe3 transport system, periplasmic component
RSPH17029_RS07885	COG5002	protein histidine kinase activity
RSPH17029_RS07895	COG0626	cystathionine gamma-synthase activity
RSPH17029_RS07905	COG0194	GDP metabolic process
RSPH17029_RS07910	COG1561	YicC-like family, N-terminal region
RSPH17029_RS07920	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
RSPH17029_RS07945	COG0559	Belongs to the binding-protein-dependent transport system permease family
RSPH17029_RS07975	COG2188	Transcriptional regulator
RSPH17029_RS07995	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
RSPH17029_RS08000	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
RSPH17029_RS08000	COG1796	DNA polymerase
RSPH17029_RS08005	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
RSPH17029_RS08020	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
RSPH17029_RS08025	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
RSPH17029_RS08075	COG0583	DNA-binding transcription factor activity
RSPH17029_RS08080	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
RSPH17029_RS08090	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
RSPH17029_RS08105	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
RSPH17029_RS08115	COG2354	Protein conserved in bacteria
RSPH17029_RS08155	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
RSPH17029_RS08165	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RSPH17029_RS08175	COG2814	Major facilitator Superfamily
RSPH17029_RS08190	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
RSPH17029_RS08195	COG1196	nuclear chromosome segregation
RSPH17029_RS08195	COG0741	lytic transglycosylase activity
RSPH17029_RS08195	COG0739	heme binding
RSPH17029_RS08210	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
RSPH17029_RS08215	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
RSPH17029_RS08220	COG0860	N-Acetylmuramoyl-L-alanine amidase
RSPH17029_RS08225	COG0436	Aminotransferase
RSPH17029_RS08235	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
RSPH17029_RS08245	COG0156	8-amino-7-oxononanoate synthase activity
RSPH17029_RS08275	COG1741	Belongs to the pirin family
RSPH17029_RS08310	COG2267	carboxylic ester hydrolase activity
RSPH17029_RS08315	COG2326	polyphosphate kinase activity
RSPH17029_RS08325	COG3842	ATPase activity
RSPH17029_RS08335	COG1176	ABC-type spermidine putrescine transport system, permease component I
RSPH17029_RS08340	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
RSPH17029_RS08370	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
RSPH17029_RS08375	COG0673	inositol 2-dehydrogenase activity
RSPH17029_RS08390	COG1028	Short-chain dehydrogenase reductase Sdr
RSPH17029_RS08395	COG0427	acetyl-CoA hydrolase
RSPH17029_RS08400	COG5001	Diguanylate cyclase
RSPH17029_RS08485	COG2198	Histidine kinase
RSPH17029_RS08485	COG0643	Histidine kinase
RSPH17029_RS08490	COG2201	protein-glutamate methylesterase activity
RSPH17029_RS08495	COG0840	transmembrane signaling receptor activity
RSPH17029_RS08500	COG1192	Involved in chromosome partitioning
RSPH17029_RS08505	COG0835	chemotaxis
RSPH17029_RS08510	COG2201	protein-glutamate methylesterase activity
RSPH17029_RS08520	COG2198	Histidine kinase
RSPH17029_RS08520	COG0643	Histidine kinase
RSPH17029_RS08535	COG1677	Flagellar hook-basal body complex protein FliE
RSPH17029_RS08555	COG1157	protein secretion by the type III secretion system
RSPH17029_RS08600	COG1684	flagellar biosynthetic protein fliR
RSPH17029_RS08630	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
RSPH17029_RS08630	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
RSPH17029_RS08670	COG4786	Flagellar basal body rod
RSPH17029_RS08675	COG4786	Flagellar basal body rod
RSPH17029_RS08680	COG1749	Flagellar hook protein flgE
RSPH17029_RS08685	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
RSPH17029_RS08690	COG1558	bacterial-type flagellum-dependent cell motility
RSPH17029_RS08720	COG3685	Protein conserved in bacteria
RSPH17029_RS08725	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RSPH17029_RS08730	COG2390	Transcriptional regulator
RSPH17029_RS08740	COG1175	transmembrane transport
RSPH17029_RS08770	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
RSPH17029_RS08775	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
RSPH17029_RS08785	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RSPH17029_RS08810	COG1034	ATP synthesis coupled electron transport
RSPH17029_RS08830	COG0713	ATP synthesis coupled electron transport
RSPH17029_RS08845	COG1007	ATP synthesis coupled electron transport
RSPH17029_RS08850	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RSPH17029_RS08860	COG2863	cytochrome
RSPH17029_RS08870	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
RSPH17029_RS08875	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
RSPH17029_RS08875	COG2010	Cytochrome c
RSPH17029_RS08880	COG0671	phosphoesterase, PA-phosphatase related
RSPH17029_RS08900	COG3916	Acyl-homoserine-lactone synthase
RSPH17029_RS08910	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
RSPH17029_RS08920	COG2943	transferase activity, transferring hexosyl groups
RSPH17029_RS08935	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
RSPH17029_RS08940	COG2011	ABC-type metal ion transport system permease component
RSPH17029_RS08945	COG1464	Belongs to the NlpA lipoprotein family
RSPH17029_RS08950	COG1757	Na H antiporter
RSPH17029_RS08990	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
RSPH17029_RS08990	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
RSPH17029_RS09010	COG3920	Histidine kinase
RSPH17029_RS09015	COG0784	Response regulator, receiver
RSPH17029_RS09020	COG2205	protein histidine kinase activity
RSPH17029_RS09045	COG1024	Enoyl-CoA hydratase
RSPH17029_RS09075	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RSPH17029_RS09095	COG3750	Belongs to the UPF0335 family
RSPH17029_RS09120	COG5002	protein histidine kinase activity
RSPH17029_RS09130	COG0745	RESPONSE REGULATOR receiver
RSPH17029_RS09135	COG1396	sequence-specific DNA binding
RSPH17029_RS09135	COG3800	Transcriptional regulator
RSPH17029_RS09145	COG1028	Short-chain dehydrogenase reductase Sdr
RSPH17029_RS09150	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RSPH17029_RS09155	COG0129	dihydroxy-acid dehydratase activity
RSPH17029_RS09160	COG0277	FAD linked oxidase domain protein
RSPH17029_RS09165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RSPH17029_RS09170	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RSPH17029_RS09175	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RSPH17029_RS09195	COG1309	transcriptional regulator
RSPH17029_RS09200	COG1309	transcriptional regulator
RSPH17029_RS09225	COG0439	Biotin carboxylase
RSPH17029_RS09265	COG4134	Bacterial extracellular solute-binding protein
RSPH17029_RS09270	COG4135	transport system, permease component
RSPH17029_RS09275	COG4136	ATPase activity
RSPH17029_RS09280	COG2340	Cysteine-rich secretory protein family
RSPH17029_RS09335	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
RSPH17029_RS09390	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
RSPH17029_RS09440	COG1755	Isoprenylcysteine carboxyl methyltransferase
RSPH17029_RS09475	COG0840	transmembrane signaling receptor activity
RSPH17029_RS09485	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
RSPH17029_RS09505	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
RSPH17029_RS09525	COG1376	ErfK ybiS ycfS ynhG family protein
RSPH17029_RS09530	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
RSPH17029_RS09535	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
RSPH17029_RS09550	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
RSPH17029_RS09570	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
RSPH17029_RS09575	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RSPH17029_RS09580	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
RSPH17029_RS09615	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
RSPH17029_RS09620	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
RSPH17029_RS09625	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
RSPH17029_RS09630	COG1063	alcohol dehydrogenase
RSPH17029_RS09635	COG0500	methyltransferase
RSPH17029_RS09640	COG0142	geranyltranstransferase activity
RSPH17029_RS09645	COG1233	COG1233 Phytoene dehydrogenase and related
RSPH17029_RS09650	COG5621	secreted hydrolase
RSPH17029_RS09660	COG1562	ergosterol biosynthetic process
RSPH17029_RS09665	COG1233	COG1233 Phytoene dehydrogenase and related
RSPH17029_RS09675	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
RSPH17029_RS09680	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
RSPH17029_RS09695	COG0644	oxidoreductase
RSPH17029_RS09700	COG2211	Major facilitator Superfamily
RSPH17029_RS09705	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
RSPH17029_RS09710	COG1719	4-vinyl reductase, 4VR
RSPH17029_RS09715	COG1032	radical SAM domain protein
RSPH17029_RS09745	COG1429	ligase activity, forming nitrogen-metal bonds
RSPH17029_RS09785	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
RSPH17029_RS09795	COG3474	cytochrome
RSPH17029_RS09810	COG1172	Belongs to the binding-protein-dependent transport system permease family
RSPH17029_RS09835	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
RSPH17029_RS09895	COG2814	Major facilitator Superfamily
RSPH17029_RS09900	COG2197	response regulator
RSPH17029_RS09905	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RSPH17029_RS09930	COG0714	Associated with various cellular activities
RSPH17029_RS09935	COG3256	nitric oxide reductase
RSPH17029_RS09940	COG2010	Cytochrome c
RSPH17029_RS10010	COG2264	protein methyltransferase activity
RSPH17029_RS10020	COG0402	S-adenosylhomocysteine deaminase activity
RSPH17029_RS10025	COG1079	Belongs to the binding-protein-dependent transport system permease family
RSPH17029_RS10030	COG4603	Belongs to the binding-protein-dependent transport system permease family
RSPH17029_RS10035	COG3845	ABC transporter
RSPH17029_RS10060	COG3842	ATPase activity
RSPH17029_RS10080	COG0587	DNA-directed DNA polymerase activity
RSPH17029_RS10095	COG0330	HflC and HflK could
RSPH17029_RS10100	COG0330	HflC and HflK could
RSPH17029_RS10115	COG1760	l-serine dehydratase
RSPH17029_RS10120	COG0697	spore germination
RSPH17029_RS10180	COG4160	amino acid transport
RSPH17029_RS10185	COG0174	glutamine synthetase
RSPH17029_RS10190	COG0519	Catalyzes the synthesis of GMP from XMP
RSPH17029_RS10220	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
RSPH17029_RS10230	COG0174	glutamine synthetase
RSPH17029_RS10235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RSPH17029_RS10240	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RSPH17029_RS10255	COG3243	poly(R)-hydroxyalkanoic acid synthase
RSPH17029_RS10275	COG1278	Cold shock
RSPH17029_RS10305	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RSPH17029_RS10305	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RSPH17029_RS10320	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
RSPH17029_RS10325	COG0358	DNA primase activity
RSPH17029_RS10330	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
RSPH17029_RS10370	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
RSPH17029_RS10380	COG3706	GGDEF domain
RSPH17029_RS10385	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RSPH17029_RS10410	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
RSPH17029_RS10415	COG0546	phosphoglycolate phosphatase activity
RSPH17029_RS10475	COG0667	Aldo Keto reductase
RSPH17029_RS10515	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
RSPH17029_RS10520	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
RSPH17029_RS10535	COG0719	Fe-S assembly protein
RSPH17029_RS10540	COG0396	ATPase activity
RSPH17029_RS10550	COG0719	Fe-S assembly protein
RSPH17029_RS10565	COG2945	thiolester hydrolase activity
RSPH17029_RS10575	COG0538	isocitrate dehydrogenase activity
RSPH17029_RS10585	COG1217	gtp-binding protein TYPA
RSPH17029_RS10590	COG0121	glutamine amidotransferase
RSPH17029_RS10620	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
RSPH17029_RS10620	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RSPH17029_RS10635	COG5642	Protein of unknown function (DUF2384)
RSPH17029_RS10650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RSPH17029_RS10655	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
RSPH17029_RS10660	COG0826	peptidase U32
RSPH17029_RS10665	COG0826	peptidase U32
RSPH17029_RS10675	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
RSPH17029_RS10685	COG0579	oxidoreductase
RSPH17029_RS10705	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RSPH17029_RS10710	COG3909	cytochrome
RSPH17029_RS10720	COG0235	Class ii aldolase
RSPH17029_RS10730	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
RSPH17029_RS10740	COG0246	Mannitol dehydrogenase
RSPH17029_RS10745	COG1028	Short-chain dehydrogenase reductase Sdr
RSPH17029_RS10755	COG1917	Cupin 2, conserved barrel domain protein
RSPH17029_RS10770	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
RSPH17029_RS10775	COG1904	glucuronate isomerase
RSPH17029_RS10780	COG1802	Transcriptional regulator
RSPH17029_RS10785	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RSPH17029_RS10810	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
RSPH17029_RS10895	COG2197	response regulator
RSPH17029_RS10910	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RSPH17029_RS10935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RSPH17029_RS10950	COG0673	inositol 2-dehydrogenase activity
RSPH17029_RS10955	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
RSPH17029_RS10965	COG1272	protein, Hemolysin III
RSPH17029_RS11035	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
RSPH17029_RS11040	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
RSPH17029_RS11070	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
RSPH17029_RS11095	COG1686	Belongs to the peptidase S11 family
RSPH17029_RS11110	COG2076	Multidrug Resistance protein
RSPH17029_RS11145	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
RSPH17029_RS11165	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
RSPH17029_RS11175	COG1183	phosphatidylcholine synthase activity
RSPH17029_RS11185	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
RSPH17029_RS11195	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
RSPH17029_RS11200	COG3768	UPF0283 membrane protein
RSPH17029_RS11205	COG3106	COG3106 Predicted ATPase
RSPH17029_RS11215	COG5002	protein histidine kinase activity
RSPH17029_RS11215	COG2176	DNA-directed DNA polymerase activity
RSPH17029_RS11220	COG0745	RESPONSE REGULATOR receiver
RSPH17029_RS11230	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
RSPH17029_RS11235	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RSPH17029_RS11250	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RSPH17029_RS11255	COG0659	secondary active sulfate transmembrane transporter activity
RSPH17029_RS11275	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
RSPH17029_RS11280	COG1764	response to oxidative stress
RSPH17029_RS11290	COG0488	(ABC) transporter
RSPH17029_RS11315	COG1278	Cold shock
RSPH17029_RS11325	COG3119	arylsulfatase activity
RSPH17029_RS11340	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
RSPH17029_RS11345	COG0756	dUTP diphosphatase activity
RSPH17029_RS11350	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
RSPH17029_RS11420	COG0604	alcohol dehydrogenase
RSPH17029_RS11430	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
RSPH17029_RS11445	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RSPH17029_RS11450	COG1595	DNA-templated transcription, initiation
RSPH17029_RS11455	COG1132	(ABC) transporter
RSPH17029_RS11460	COG5002	protein histidine kinase activity
RSPH17029_RS11460	COG5000	phosphorelay sensor kinase activity
RSPH17029_RS11475	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
RSPH17029_RS11480	COG1530	ribonuclease E activity
RSPH17029_RS11485	COG0424	maF-like protein
RSPH17029_RS11495	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RSPH17029_RS11495	COG3153	acetyltransferase
RSPH17029_RS11510	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
RSPH17029_RS11520	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
RSPH17029_RS11565	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RSPH17029_RS11580	COG1396	sequence-specific DNA binding
RSPH17029_RS11595	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RSPH17029_RS11600	COG1116	anion transmembrane transporter activity
RSPH17029_RS11605	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RSPH17029_RS11610	COG0352	thiamine-phosphate diphosphorylase activity
RSPH17029_RS11610	COG0351	phosphomethylpyrimidine kinase
RSPH17029_RS11615	COG0352	thiamine-phosphate diphosphorylase activity
RSPH17029_RS11625	COG0741	lytic transglycosylase activity
RSPH17029_RS11625	COG1196	nuclear chromosome segregation
RSPH17029_RS11625	COG0739	heme binding
RSPH17029_RS11635	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
RSPH17029_RS11640	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
RSPH17029_RS11655	COG0471	metal ion transport
RSPH17029_RS11655	COG3273	potassium ion transport
RSPH17029_RS11660	COG1692	metallophosphoesterase
RSPH17029_RS11665	COG1201	RNA secondary structure unwinding
RSPH17029_RS11700	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RSPH17029_RS11705	COG0037	tRNA processing
RSPH17029_RS11715	COG2885	chlorophyll binding
RSPH17029_RS11730	COG0848	biopolymer transport protein
RSPH17029_RS11740	COG0824	Thioesterase
RSPH17029_RS11755	COG0084	hydrolase, TatD family'
RSPH17029_RS11780	COG0181	hydroxymethylbilane synthase activity
RSPH17029_RS11795	COG0408	coproporphyrinogen oxidase activity
RSPH17029_RS11805	COG1028	Short-chain dehydrogenase reductase Sdr
RSPH17029_RS11815	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
RSPH17029_RS11825	COG1686	Belongs to the peptidase S11 family
RSPH17029_RS11845	COG0348	domain, Protein
RSPH17029_RS11850	COG2010	Cytochrome c
RSPH17029_RS11875	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RSPH17029_RS11880	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RSPH17029_RS11885	COG0438	transferase activity, transferring glycosyl groups
RSPH17029_RS11890	COG4172	Belongs to the ABC transporter superfamily
RSPH17029_RS11895	COG4239	(ABC) transporter, permease
RSPH17029_RS11900	COG4174	ABC transporter (Permease)
RSPH17029_RS11905	COG4166	transmembrane transport
RSPH17029_RS11925	COG2816	NAD+ diphosphatase activity
RSPH17029_RS11930	COG0737	Belongs to the 5'-nucleotidase family
RSPH17029_RS11935	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
RSPH17029_RS11940	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
RSPH17029_RS11985	COG1183	phosphatidylcholine synthase activity
RSPH17029_RS11995	COG1522	sequence-specific DNA binding
RSPH17029_RS12000	COG0686	Belongs to the AlaDH PNT family
RSPH17029_RS12010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RSPH17029_RS12035	COG0019	diaminopimelate decarboxylase activity
RSPH17029_RS12050	COG2884	Cell division ATP-binding protein ftsE
RSPH17029_RS12070	COG1763	Mo-molybdopterin cofactor biosynthetic process
RSPH17029_RS12105	COG1960	acyl-CoA dehydrogenase activity
RSPH17029_RS12110	COG0009	L-threonylcarbamoyladenylate synthase
RSPH17029_RS12115	COG2818	Glycosylase
RSPH17029_RS12140	COG0142	geranyltranstransferase activity
RSPH17029_RS12175	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RSPH17029_RS12180	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
RSPH17029_RS12185	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RSPH17029_RS12185	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RSPH17029_RS12205	COG1596	polysaccharide export
RSPH17029_RS12210	COG1846	Transcriptional regulator
RSPH17029_RS12230	COG0534	Mate efflux family protein
RSPH17029_RS12240	COG2326	polyphosphate kinase activity
RSPH17029_RS12255	COG0187	DNA topoisomerase II activity
RSPH17029_RS12260	COG1312	Catalyzes the dehydration of D-mannonate
RSPH17029_RS12275	COG1136	(ABC) transporter
RSPH17029_RS12280	COG4591	ABC-type transport system involved in lipoprotein release permease component
RSPH17029_RS12290	COG0628	permease
RSPH17029_RS12300	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
RSPH17029_RS12305	COG0248	Ppx GppA phosphatase
RSPH17029_RS12320	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
RSPH17029_RS12345	COG0535	radical SAM domain protein
RSPH17029_RS12350	COG0535	radical SAM domain protein
RSPH17029_RS12360	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
RSPH17029_RS12380	COG1492	cobalamin metabolic process
RSPH17029_RS12400	COG1234	tRNA 3'-trailer cleavage
RSPH17029_RS12405	COG1872	DUF167
RSPH17029_RS12420	COG4608	Belongs to the ABC transporter superfamily
RSPH17029_RS12425	COG0444	Belongs to the ABC transporter superfamily
RSPH17029_RS12430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RSPH17029_RS12435	COG0601	transmembrane transport
RSPH17029_RS12460	COG0346	lactoylglutathione lyase activity
RSPH17029_RS12490	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
RSPH17029_RS12495	COG0513	Belongs to the DEAD box helicase family
RSPH17029_RS12510	COG0596	Alpha beta hydrolase
RSPH17029_RS12520	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
RSPH17029_RS12555	COG0617	tRNA 3'-terminal CCA addition
RSPH17029_RS12555	COG3620	sequence-specific DNA binding
RSPH17029_RS12555	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
RSPH17029_RS12565	COG0012	GTP binding
RSPH17029_RS12570	COG0662	Cupin 2, conserved barrel domain protein
RSPH17029_RS12570	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
RSPH17029_RS12620	COG0457	Tetratricopeptide repeat
RSPH17029_RS12640	COG0745	RESPONSE REGULATOR receiver
RSPH17029_RS12660	COG0679	Auxin Efflux Carrier
RSPH17029_RS12665	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
RSPH17029_RS12675	COG2423	ornithine cyclodeaminase activity
RSPH17029_RS12690	COG4106	trans-aconitate 2-methyltransferase activity
RSPH17029_RS12700	COG0697	spore germination
RSPH17029_RS12705	COG0473	3-isopropylmalate dehydrogenase activity
RSPH17029_RS12740	COG0799	negative regulation of ribosome biogenesis
RSPH17029_RS12770	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
RSPH17029_RS12775	COG0242	peptide deformylase activity
RSPH17029_RS12780	COG0242	peptide deformylase activity
RSPH17029_RS12785	COG0242	peptide deformylase activity
RSPH17029_RS12810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RSPH17029_RS12810	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
RSPH17029_RS12820	COG0741	lytic transglycosylase activity
RSPH17029_RS12825	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RSPH17029_RS12835	COG2897	thiosulfate sulfurtransferase activity
RSPH17029_RS12845	COG0004	ammonium transporteR
RSPH17029_RS12850	COG0347	Belongs to the P(II) protein family
RSPH17029_RS12865	COG2853	Lipoprotein
RSPH17029_RS12875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RSPH17029_RS12900	COG2154	pterin-4-alpha-carbinolamine dehydratase
RSPH17029_RS12905	COG0678	peroxiredoxin activity
RSPH17029_RS12915	COG0742	ribosomal rna small subunit methyltransferase
RSPH17029_RS12920	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RSPH17029_RS12930	COG0803	Belongs to the bacterial solute-binding protein 9 family
RSPH17029_RS12935	COG1121	(ABC) transporter
RSPH17029_RS12940	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RSPH17029_RS12945	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RSPH17029_RS12980	COG1028	Short-chain dehydrogenase reductase Sdr
RSPH17029_RS12990	COG0312	modulator of DNA gyrase
RSPH17029_RS13005	COG1028	Short-chain dehydrogenase reductase Sdr
RSPH17029_RS13015	COG0848	biopolymer transport protein
RSPH17029_RS13025	COG0024	Methionine aminopeptidase
RSPH17029_RS13030	COG1058	Belongs to the CinA family
RSPH17029_RS13030	COG1546	Belongs to the CinA family
RSPH17029_RS13045	COG0583	DNA-binding transcription factor activity
RSPH17029_RS13055	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
RSPH17029_RS13060	COG0285	dihydrofolate synthase activity
RSPH17029_RS13070	COG0793	Belongs to the peptidase S41A family
RSPH17029_RS13085	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RSPH17029_RS13090	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
RSPH17029_RS13120	COG1116	anion transmembrane transporter activity
RSPH17029_RS13130	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RSPH17029_RS13160	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
RSPH17029_RS13165	COG1877	trehalose-phosphatase activity
RSPH17029_RS13170	COG4187	Peptidase family M20/M25/M40
RSPH17029_RS13190	COG0737	Belongs to the 5'-nucleotidase family
RSPH17029_RS13215	COG0604	alcohol dehydrogenase
RSPH17029_RS13220	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
RSPH17029_RS13220	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
RSPH17029_RS13235	COG0508	dehydrogenase complex catalyzes the overall conversion of
RSPH17029_RS13240	COG0567	Dehydrogenase, E1 component
RSPH17029_RS13280	COG2030	dehydratase
RSPH17029_RS13320	COG1802	Transcriptional regulator
RSPH17029_RS13355	COG1072	(Pantothenic acid kinase))
RSPH17029_RS13380	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
RSPH17029_RS13380	COG2111	Na H antiporter
RSPH17029_RS13385	COG1006	Multisubunit Na H antiporter MnhC subunit
RSPH17029_RS13390	COG0651	ATP synthesis coupled electron transport
RSPH17029_RS13395	COG1863	multisubunit Na H antiporter MnhE subunit
RSPH17029_RS13400	COG2212	antiporter activity
RSPH17029_RS13405	COG1320	monovalent cation:proton antiporter activity
RSPH17029_RS13425	COG1573	uracil-dna glycosylase
RSPH17029_RS13460	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
RSPH17029_RS13485	COG1253	flavin adenine dinucleotide binding
RSPH17029_RS13495	COG2304	oxidoreductase activity
RSPH17029_RS13500	COG0071	Belongs to the small heat shock protein (HSP20) family
RSPH17029_RS13510	COG0247	lactate metabolic process
RSPH17029_RS13515	COG0277	FAD linked oxidase domain protein
RSPH17029_RS13520	COG0277	FAD linked oxidase domain protein
RSPH17029_RS13545	COG0714	Associated with various cellular activities
RSPH17029_RS13565	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RSPH17029_RS13565	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RSPH17029_RS13575	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RSPH17029_RS13580	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
RSPH17029_RS13585	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
RSPH17029_RS13590	COG2885	chlorophyll binding
RSPH17029_RS13610	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
RSPH17029_RS13625	COG0640	Transcriptional regulator
RSPH17029_RS13630	COG0318	PFAM AMP-dependent synthetase and ligase
RSPH17029_RS13635	COG1192	Involved in chromosome partitioning
RSPH17029_RS13650	COG0336	Belongs to the RNA methyltransferase TrmD family
RSPH17029_RS13690	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
RSPH17029_RS13710	COG3852	Histidine kinase
RSPH17029_RS13730	COG0594	ribonuclease P activity
RSPH17029_RS13760	COG0218	Necessary for normal cell division and for the maintenance of normal septation
RSPH17029_RS13765	COG1028	Short-chain dehydrogenase reductase Sdr
RSPH17029_RS13785	COG0314	molybdopterin synthase activity
RSPH17029_RS13795	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
RSPH17029_RS13800	COG0322	excinuclease ABC activity
RSPH17029_RS13805	COG1028	Short-chain dehydrogenase reductase Sdr
RSPH17029_RS13815	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
RSPH17029_RS13815	COG0616	signal peptide processing
RSPH17029_RS13835	COG3383	formate dehydrogenase (NAD+) activity
RSPH17029_RS13840	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
RSPH17029_RS13855	COG0438	transferase activity, transferring glycosyl groups
RSPH17029_RS13855	COG0297	glycogen (starch) synthase activity
RSPH17029_RS13860	COG0745	RESPONSE REGULATOR receiver
RSPH17029_RS13875	COG4221	oxidoreductase activity
RSPH17029_RS13900	COG1595	DNA-templated transcription, initiation
RSPH17029_RS13905	COG3806	Anti-sigma factor
RSPH17029_RS13915	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
RSPH17029_RS13920	COG0612	Peptidase, M16
RSPH17029_RS13925	COG0612	Peptidase, M16
RSPH17029_RS13935	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
RSPH17029_RS13965	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
RSPH17029_RS14015	COG0438	transferase activity, transferring glycosyl groups
RSPH17029_RS14050	COG0587	DNA-directed DNA polymerase activity
RSPH17029_RS14055	COG2951	lytic endotransglycosylase activity
RSPH17029_RS14060	COG0557	exoribonuclease II activity
RSPH17029_RS14065	COG2153	protein acetylation
RSPH17029_RS14080	COG2323	membrane
RSPH17029_RS14100	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
RSPH17029_RS14105	COG0142	geranyltranstransferase activity
RSPH17029_RS14110	COG1722	exodeoxyribonuclease VII activity
RSPH17029_RS14115	COG0123	including yeast histone deacetylase and acetoin utilization protein
RSPH17029_RS14120	COG0745	RESPONSE REGULATOR receiver
RSPH17029_RS14125	COG1846	Transcriptional regulator
RSPH17029_RS14130	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RSPH17029_RS14135	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
RSPH17029_RS14145	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RSPH17029_RS14190	COG0517	IMP dehydrogenase activity
RSPH17029_RS14190	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
RSPH17029_RS14205	COG1137	ATPase activity
RSPH17029_RS14210	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
RSPH17029_RS14215	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RSPH17029_RS14225	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
RSPH17029_RS14230	COG1218	3'(2'),5'-bisphosphate nucleotidase
RSPH17029_RS14260	COG0494	nUDIX hydrolase
RSPH17029_RS14265	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
RSPH17029_RS14270	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
RSPH17029_RS14315	COG1070	Carbohydrate kinase
RSPH17029_RS14320	COG1129	ABC transporter
RSPH17029_RS14325	COG4214	carbohydrate transport
RSPH17029_RS14330	COG4213	ABC transporter substrate-binding protein
RSPH17029_RS14335	COG1940	carbohydrate kinase activity
RSPH17029_RS14340	COG0729	surface antigen
RSPH17029_RS14345	COG2911	Protein conserved in bacteria
RSPH17029_RS14350	COG1295	ribonuclease BN
RSPH17029_RS14365	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
RSPH17029_RS14375	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
RSPH17029_RS14390	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RSPH17029_RS14395	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
RSPH17029_RS14400	COG1040	competence protein
RSPH17029_RS14430	COG3034	peptidoglycan biosynthetic process
RSPH17029_RS14435	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
RSPH17029_RS14440	COG1132	(ABC) transporter
RSPH17029_RS14445	COG1132	(ABC) transporter
RSPH17029_RS14450	COG0617	tRNA 3'-terminal CCA addition
RSPH17029_RS14455	COG0494	nUDIX hydrolase
RSPH17029_RS14470	COG0745	RESPONSE REGULATOR receiver
RSPH17029_RS14480	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
RSPH17029_RS14505	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
RSPH17029_RS14505	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
RSPH17029_RS14510	COG0281	malic enzyme
RSPH17029_RS14510	COG0280	phosphate acetyltransferase
RSPH17029_RS14520	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
RSPH17029_RS14525	COG1420	regulation of RNA biosynthetic process
RSPH17029_RS14535	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
RSPH17029_RS14540	COG0251	oxidation-reduction process
RSPH17029_RS14545	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RSPH17029_RS14550	COG2832	Protein of unknown function (DUF454)
RSPH17029_RS14580	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
RSPH17029_RS14585	COG1981	membrane
RSPH17029_RS14590	COG0424	maF-like protein
RSPH17029_RS14600	COG0237	dephospho-CoA kinase activity
RSPH17029_RS14630	COG2840	Smr protein MutS2
RSPH17029_RS14640	COG1609	Transcriptional regulator
RSPH17029_RS14650	COG0673	inositol 2-dehydrogenase activity
RSPH17029_RS14655	COG1129	ABC transporter
RSPH17029_RS14660	COG1172	Belongs to the binding-protein-dependent transport system permease family
RSPH17029_RS14665	COG1879	ABC-type sugar transport system periplasmic component
RSPH17029_RS14695	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
RSPH17029_RS14705	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
RSPH17029_RS14710	COG3243	poly(R)-hydroxyalkanoic acid synthase
RSPH17029_RS14715	COG2267	carboxylic ester hydrolase activity
RSPH17029_RS14730	COG2200	EAL domain
RSPH17029_RS14745	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
RSPH17029_RS14760	COG2205	protein histidine kinase activity
RSPH17029_RS14765	COG0745	RESPONSE REGULATOR receiver
RSPH17029_RS14770	COG3237	CsbD-like
RSPH17029_RS14790	COG0784	Response regulator, receiver
RSPH17029_RS14800	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RSPH17029_RS14900	COG0022	dehydrogenase e1 component
RSPH17029_RS14905	COG1960	acyl-CoA dehydrogenase activity
RSPH17029_RS14910	COG0583	DNA-binding transcription factor activity
RSPH17029_RS14915	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
RSPH17029_RS14945	COG1749	Flagellar hook protein flgE
RSPH17029_RS14960	COG1706	bacterial-type flagellum-dependent cell motility
RSPH17029_RS14965	COG4191	Histidine kinase
RSPH17029_RS14965	COG0784	Response regulator, receiver
RSPH17029_RS14975	COG1338	Plays a role in the flagellum-specific transport system
RSPH17029_RS14980	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
RSPH17029_RS14990	COG1766	The M ring may be actively involved in energy transduction
RSPH17029_RS15010	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
RSPH17029_RS15025	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
RSPH17029_RS15035	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
RSPH17029_RS15050	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
RSPH17029_RS15060	COG4786	Flagellar basal body rod
RSPH17029_RS15065	COG4786	Flagellar basal body rod
RSPH17029_RS15070	COG1987	bacterial-type flagellum assembly
RSPH17029_RS15075	COG1677	Flagellar hook-basal body complex protein FliE
RSPH17029_RS15080	COG1558	bacterial-type flagellum-dependent cell motility
RSPH17029_RS15085	COG1815	bacterial-type flagellum-dependent cell motility
RSPH17029_RS15215	COG2373	Large extracellular alpha-helical protein
RSPH17029_RS15740	COG0019	diaminopimelate decarboxylase activity
RSPH17029_RS15800	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RSPH17029_RS15975	COG1074	ATP-dependent DNA helicase activity
RSPH17029_RS16890	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
RSPH17029_RS17175	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
RSPH17029_RS17285	COG0612	Peptidase, M16
RSPH17029_RS17440	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
RSPH17029_RS17650	COG4964	Belongs to the GSP D family
RSPH17029_RS18175	COG0006	proline dipeptidase activity
RSPH17029_RS18540	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
RSPH17029_RS18565	COG3135	benzoate transporter
RSPH17029_RS18905	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
RSPH17029_RS18925	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
RSPH17029_RS18950	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
RSPH17029_RS18950	COG1754	DNA topoisomerase type I activity
RSPH17029_RS19335	COG0318	PFAM AMP-dependent synthetase and ligase
RSPH17029_RS19350	COG1238	metal cluster binding
RSPH17029_RS19390	COG1187	pseudouridine synthase activity
RSPH17029_RS19460	COG1129	ABC transporter
RSPH17029_RS19490	COG0745	RESPONSE REGULATOR receiver
RSPH17029_RS19680	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
RSPH17029_RS19715	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RSPH17029_RS19995	COG4206	TonB-dependent receptor
RSPH17029_RS20065	COG2308	Evidence 4 Homologs of previously reported genes of
RSPH17029_RS20070	COG2308	Evidence 4 Homologs of previously reported genes of
RSPH17029_RS20145	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
RSPH17029_RS20250	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
RSPH17029_RS20255	COG1640	4-alpha-glucanotransferase
RSPH17029_RS20305	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
RSPH17029_RS20495	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
RSPH17029_RS20615	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RSPH17029_RS20655	COG2205	protein histidine kinase activity
RSPH17029_RS20655	COG3437	response regulator, receiver
RSPH17029_RS20655	COG3850	Histidine kinase
RSPH17029_RS20655	COG4999	Histidine kinase
RSPH17029_RS20725	COG3734	2-keto-3-deoxy-galactonokinase