locus-tag	class	description
G5B40_RS00015	COG5002	protein histidine kinase activity
G5B40_RS00025	COG0527	aspartate kinase activity
G5B40_RS00040	COG0303	'Molybdopterin
G5B40_RS00045	COG0315	cyclic pyranopterin monophosphate synthase activity
G5B40_RS00050	COG0134	indole-3-glycerol-phosphate synthase activity
G5B40_RS00055	COG0538	isocitrate dehydrogenase activity
G5B40_RS00070	COG0404	The glycine cleavage system catalyzes the degradation of glycine
G5B40_RS00075	COG0583	DNA-binding transcription factor activity
G5B40_RS00090	COG1612	heme a metabolic process
G5B40_RS00095	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G5B40_RS00105	COG0400	carboxylic ester hydrolase activity
G5B40_RS00125	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
G5B40_RS00145	COG0047	phosphoribosylformylglycinamidine synthase activity
G5B40_RS00150	COG1063	alcohol dehydrogenase
G5B40_RS00155	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G5B40_RS00160	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
G5B40_RS00170	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
G5B40_RS00180	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G5B40_RS00190	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
G5B40_RS00195	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
G5B40_RS00220	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
G5B40_RS00240	COG2326	polyphosphate kinase activity
G5B40_RS00245	COG2267	carboxylic ester hydrolase activity
G5B40_RS00250	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
G5B40_RS00265	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
G5B40_RS00275	COG0318	PFAM AMP-dependent synthetase and ligase
G5B40_RS00285	COG1028	Short-chain dehydrogenase reductase Sdr
G5B40_RS00290	COG1946	Acyl-CoA thioesterase
G5B40_RS00320	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G5B40_RS00335	COG0395	ABC-type sugar transport system, permease component
G5B40_RS00340	COG3842	ATPase activity
G5B40_RS00345	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
G5B40_RS00350	COG1176	ABC-type spermidine putrescine transport system, permease component I
G5B40_RS00355	COG1177	transmembrane transport
G5B40_RS00360	COG3842	ATPase activity
G5B40_RS00380	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
G5B40_RS00410	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
G5B40_RS00415	COG0741	lytic transglycosylase activity
G5B40_RS00415	COG1196	nuclear chromosome segregation
G5B40_RS00415	COG0739	heme binding
G5B40_RS00430	COG0583	DNA-binding transcription factor activity
G5B40_RS00460	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
G5B40_RS00465	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G5B40_RS00470	COG2354	Protein conserved in bacteria
G5B40_RS00515	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G5B40_RS00575	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G5B40_RS00585	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G5B40_RS00590	COG4948	Mandelate Racemase Muconate Lactonizing
G5B40_RS00600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G5B40_RS00610	COG0747	negative chemotaxis
G5B40_RS00630	COG1028	Short-chain dehydrogenase reductase Sdr
G5B40_RS00645	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
G5B40_RS00645	COG0546	phosphoglycolate phosphatase activity
G5B40_RS00655	COG1960	acyl-CoA dehydrogenase activity
G5B40_RS00670	COG0259	pyridoxamine-phosphate oxidase activity
G5B40_RS00675	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
G5B40_RS00680	COG1028	Short-chain dehydrogenase reductase Sdr
G5B40_RS00700	COG4536	flavin adenine dinucleotide binding
G5B40_RS00710	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
G5B40_RS00725	COG0590	tRNA wobble adenosine to inosine editing
G5B40_RS00735	COG1187	pseudouridine synthase activity
G5B40_RS00745	COG3023	N-Acetylmuramoyl-L-alanine amidase
G5B40_RS00760	COG4191	Histidine kinase
G5B40_RS00775	COG0230	Belongs to the bacterial ribosomal protein bL34 family
G5B40_RS00780	COG0594	ribonuclease P activity
G5B40_RS00785	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
G5B40_RS00790	COG0037	tRNA processing
G5B40_RS00795	COG0154	amidase activity
G5B40_RS00800	COG3663	DNA glycosylase
G5B40_RS00805	COG2308	Evidence 4 Homologs of previously reported genes of
G5B40_RS00825	COG0667	Aldo Keto reductase
G5B40_RS00840	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
G5B40_RS00845	COG0697	spore germination
G5B40_RS00865	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
G5B40_RS00885	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
G5B40_RS00915	COG1561	YicC-like family, N-terminal region
G5B40_RS00920	COG0194	GDP metabolic process
G5B40_RS00940	COG1028	Short-chain dehydrogenase reductase Sdr
G5B40_RS00945	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G5B40_RS00980	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
G5B40_RS00990	COG0737	Belongs to the 5'-nucleotidase family
G5B40_RS00995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G5B40_RS01000	COG0328	RNA-DNA hybrid ribonuclease activity
G5B40_RS01015	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
G5B40_RS01020	COG0402	S-adenosylhomocysteine deaminase activity
G5B40_RS01030	COG4603	Belongs to the binding-protein-dependent transport system permease family
G5B40_RS01045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G5B40_RS01050	COG0601	transmembrane transport
G5B40_RS01055	COG4166	transmembrane transport
G5B40_RS01060	COG4608	Belongs to the ABC transporter superfamily
G5B40_RS01065	COG0444	Belongs to the ABC transporter superfamily
G5B40_RS01075	COG2171	N-acyltransferase activity
G5B40_RS01110	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
G5B40_RS01135	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
G5B40_RS01135	COG0321	lipoyl(octanoyl) transferase activity
G5B40_RS01140	COG0084	hydrolase, TatD family'
G5B40_RS01145	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
G5B40_RS01150	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
G5B40_RS01155	COG1686	Belongs to the peptidase S11 family
G5B40_RS01200	COG0508	dehydrogenase complex catalyzes the overall conversion of
G5B40_RS01205	COG0508	dehydrogenase complex catalyzes the overall conversion of
G5B40_RS01205	COG0022	dehydrogenase e1 component
G5B40_RS01210	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
G5B40_RS01215	COG4569	acetaldehyde dehydrogenase (acetylating) activity
G5B40_RS01235	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
G5B40_RS01240	COG3842	ATPase activity
G5B40_RS01260	COG3639	organic phosphonate transmembrane transporter activity
G5B40_RS01265	COG3639	organic phosphonate transmembrane transporter activity
G5B40_RS01270	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
G5B40_RS01290	COG4191	Histidine kinase
G5B40_RS01295	COG4566	intracellular signal transduction
G5B40_RS01315	COG0789	Transcriptional regulator
G5B40_RS01335	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G5B40_RS01350	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
G5B40_RS01380	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
G5B40_RS01385	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
G5B40_RS01390	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
G5B40_RS01400	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
G5B40_RS01410	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
G5B40_RS01415	COG3243	poly(R)-hydroxyalkanoic acid synthase
G5B40_RS01420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G5B40_RS01425	COG0842	Transport permease protein
G5B40_RS01425	COG1129	ABC transporter
G5B40_RS01430	COG0842	Transport permease protein
G5B40_RS01440	COG1414	Transcriptional regulator
G5B40_RS01445	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
G5B40_RS01450	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G5B40_RS01465	COG0544	peptidyl-prolyl cis-trans isomerase activity
G5B40_RS01475	COG0740	serine-type endopeptidase activity
G5B40_RS01480	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
G5B40_RS01485	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
G5B40_RS01520	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G5B40_RS01525	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G5B40_RS01530	COG0649	NAD binding
G5B40_RS01570	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
G5B40_RS01575	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G5B40_RS01585	COG0713	ATP synthesis coupled electron transport
G5B40_RS01610	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
G5B40_RS01620	COG0513	Belongs to the DEAD box helicase family
G5B40_RS01630	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G5B40_RS01635	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
G5B40_RS01645	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
G5B40_RS01650	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
G5B40_RS01660	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
G5B40_RS01685	COG0557	exoribonuclease II activity
G5B40_RS01700	COG0587	DNA-directed DNA polymerase activity
G5B40_RS01710	COG1802	Transcriptional regulator
G5B40_RS01720	COG1802	Transcriptional regulator
G5B40_RS01725	COG0318	PFAM AMP-dependent synthetase and ligase
G5B40_RS01735	COG0411	ABC transporter
G5B40_RS01755	COG4166	transmembrane transport
G5B40_RS01775	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G5B40_RS01775	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G5B40_RS01780	COG0509	glycine decarboxylation via glycine cleavage system
G5B40_RS01785	COG0404	The glycine cleavage system catalyzes the degradation of glycine
G5B40_RS01790	COG2270	Major facilitator Superfamily
G5B40_RS01795	COG3842	ATPase activity
G5B40_RS01800	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G5B40_RS01805	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G5B40_RS01810	COG0805	protein transport
G5B40_RS01830	COG1396	sequence-specific DNA binding
G5B40_RS01835	COG1028	Short-chain dehydrogenase reductase Sdr
G5B40_RS01840	COG4166	transmembrane transport
G5B40_RS01855	COG0772	Belongs to the SEDS family
G5B40_RS01860	COG0768	penicillin binding
G5B40_RS01890	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G5B40_RS01900	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G5B40_RS01915	COG0187	DNA topoisomerase II activity
G5B40_RS01925	COG0596	Alpha beta hydrolase
G5B40_RS01950	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
G5B40_RS01960	COG0330	HflC and HflK could
G5B40_RS01965	COG0330	HflC and HflK could
G5B40_RS01970	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G5B40_RS01975	COG1396	sequence-specific DNA binding
G5B40_RS02000	COG2040	homocysteine
G5B40_RS02015	COG2124	cytochrome p450
G5B40_RS02045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G5B40_RS02050	COG0579	oxidoreductase
G5B40_RS02065	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G5B40_RS02080	COG0405	Gamma-glutamyltransferase
G5B40_RS02085	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
G5B40_RS02090	COG0745	RESPONSE REGULATOR receiver
G5B40_RS02095	COG2205	protein histidine kinase activity
G5B40_RS02100	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
G5B40_RS02115	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G5B40_RS02130	COG1028	Short-chain dehydrogenase reductase Sdr
G5B40_RS02135	COG1028	Short-chain dehydrogenase reductase Sdr
G5B40_RS02140	COG0659	secondary active sulfate transmembrane transporter activity
G5B40_RS02145	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G5B40_RS02150	COG0697	spore germination
G5B40_RS02155	COG0540	Belongs to the ATCase OTCase family
G5B40_RS02160	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
G5B40_RS02165	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
G5B40_RS02170	COG0758	DNA mediated transformation
G5B40_RS02175	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G5B40_RS02175	COG1754	DNA topoisomerase type I activity
G5B40_RS02200	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G5B40_RS02205	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
G5B40_RS02210	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
G5B40_RS02215	COG1137	ATPase activity
G5B40_RS02230	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
G5B40_RS02230	COG0517	IMP dehydrogenase activity
G5B40_RS02245	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
G5B40_RS02255	COG1469	GTP cyclohydrolase I activity
G5B40_RS02265	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G5B40_RS02275	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G5B40_RS02280	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
G5B40_RS02305	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G5B40_RS02315	COG0559	Belongs to the binding-protein-dependent transport system permease family
G5B40_RS02320	COG4177	L-phenylalanine transmembrane transporter activity
G5B40_RS02355	COG0604	alcohol dehydrogenase
G5B40_RS02370	COG0583	DNA-binding transcription factor activity
G5B40_RS02400	COG1414	Transcriptional regulator
G5B40_RS02405	COG0438	transferase activity, transferring glycosyl groups
G5B40_RS02430	COG0071	Belongs to the small heat shock protein (HSP20) family
G5B40_RS02495	COG0077	Prephenate dehydratase
G5B40_RS02500	COG3474	cytochrome
G5B40_RS02505	COG2885	chlorophyll binding
G5B40_RS02515	COG4948	Mandelate Racemase Muconate Lactonizing
G5B40_RS02525	COG4166	transmembrane transport
G5B40_RS02530	COG4166	transmembrane transport
G5B40_RS02540	COG4174	ABC transporter (Permease)
G5B40_RS02545	COG4239	(ABC) transporter, permease
G5B40_RS02550	COG4172	Belongs to the ABC transporter superfamily
G5B40_RS02565	COG0667	Aldo Keto reductase
G5B40_RS02585	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
G5B40_RS02595	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
G5B40_RS02615	COG2989	Protein conserved in bacteria
G5B40_RS02620	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
G5B40_RS02625	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
G5B40_RS02665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G5B40_RS02670	COG4597	amino acid ABC transporter
G5B40_RS02675	COG0765	amino acid transport
G5B40_RS02680	COG1126	abc transporter atp-binding protein
G5B40_RS02735	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
G5B40_RS02745	COG2207	Transcriptional regulator
G5B40_RS02750	COG2223	nitrite transmembrane transporter activity
G5B40_RS02755	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G5B40_RS02765	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
G5B40_RS02770	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G5B40_RS02775	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G5B40_RS02790	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
G5B40_RS02795	COG0697	spore germination
G5B40_RS02805	COG0076	glutamate decarboxylase activity
G5B40_RS02810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G5B40_RS02815	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
G5B40_RS02820	COG1923	regulation of RNA biosynthetic process
G5B40_RS02825	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G5B40_RS02830	COG0569	domain protein
G5B40_RS02835	COG2204	response regulator
G5B40_RS02840	COG5000	phosphorelay sensor kinase activity
G5B40_RS02855	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
G5B40_RS02860	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
G5B40_RS02860	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
G5B40_RS02870	COG1058	Belongs to the CinA family
G5B40_RS02870	COG1546	Belongs to the CinA family
G5B40_RS02875	COG2867	negative regulation of translational initiation
G5B40_RS02900	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
G5B40_RS02920	COG0798	PFAM Bile acid sodium symporter
G5B40_RS02930	COG0431	NADPH-dependent FMN reductase
G5B40_RS02935	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G5B40_RS02950	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
G5B40_RS02960	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
G5B40_RS02980	COG0629	single-stranded DNA binding
G5B40_RS02985	COG3956	TIGRFAM MazG family protein
G5B40_RS02990	COG1840	ABC-type Fe3 transport system, periplasmic component
G5B40_RS03015	COG0148	phosphopyruvate hydratase activity
G5B40_RS03035	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
G5B40_RS03040	COG0508	dehydrogenase complex catalyzes the overall conversion of
G5B40_RS03040	COG0022	dehydrogenase e1 component
G5B40_RS03045	COG0508	dehydrogenase complex catalyzes the overall conversion of
G5B40_RS03055	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
G5B40_RS03140	COG4695	Portal protein
G5B40_RS03155	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
G5B40_RS03160	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G5B40_RS03175	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
G5B40_RS03180	COG0360	Binds together with S18 to 16S ribosomal RNA
G5B40_RS03185	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
G5B40_RS03190	COG0359	binds to the 23S rRNA
G5B40_RS03195	COG0305	Participates in initiation and elongation during chromosome replication
G5B40_RS03205	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G5B40_RS03210	COG1127	ABC transporter
G5B40_RS03230	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
G5B40_RS03235	COG1028	Short-chain dehydrogenase reductase Sdr
G5B40_RS03240	COG1160	GTP binding
G5B40_RS03245	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G5B40_RS03265	COG5265	(ABC) transporter
G5B40_RS03285	COG3737	Protein of unknown function (DUF498/DUF598)
G5B40_RS03290	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G5B40_RS03295	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G5B40_RS03300	COG1862	Preprotein translocase
G5B40_RS03325	COG0778	Nitroreductase
G5B40_RS03345	COG0346	lactoylglutathione lyase activity
G5B40_RS03350	COG3045	CreA protein
G5B40_RS03380	COG0436	Aminotransferase
G5B40_RS03395	COG0511	ligase activity, forming carbon-carbon bonds
G5B40_RS03400	COG0439	Biotin carboxylase
G5B40_RS03405	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
G5B40_RS03415	COG4106	trans-aconitate 2-methyltransferase activity
G5B40_RS03440	COG0316	Belongs to the HesB IscA family
G5B40_RS03450	COG0149	triose-phosphate isomerase activity
G5B40_RS03485	COG0330	HflC and HflK could
G5B40_RS03495	COG2770	Histidine kinase
G5B40_RS03495	COG2208	phosphoserine phosphatase activity
G5B40_RS03500	COG0488	(ABC) transporter
G5B40_RS03505	COG2095	MarC family integral membrane protein
G5B40_RS03515	COG5012	cobalamin binding
G5B40_RS03520	COG1410	methionine synthase
G5B40_RS03520	COG0646	methionine synthase
G5B40_RS03530	COG2166	iron-sulfur cluster assembly
G5B40_RS03540	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
G5B40_RS03545	COG2885	chlorophyll binding
G5B40_RS03555	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
G5B40_RS03570	COG0484	heat shock protein binding
G5B40_RS03615	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G5B40_RS03635	COG1609	Transcriptional regulator
G5B40_RS03645	COG0673	inositol 2-dehydrogenase activity
G5B40_RS03655	COG1175	transmembrane transport
G5B40_RS03660	COG0395	ABC-type sugar transport system, permease component
G5B40_RS03675	COG3842	ATPase activity
G5B40_RS03695	COG0747	negative chemotaxis
G5B40_RS03705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G5B40_RS03710	COG4172	Belongs to the ABC transporter superfamily
G5B40_RS03725	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
G5B40_RS03730	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G5B40_RS03730	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G5B40_RS03750	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
G5B40_RS03755	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
G5B40_RS03760	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
G5B40_RS03765	COG4942	peptidase
G5B40_RS03765	COG1388	LysM domain
G5B40_RS03775	COG0655	NAD(P)H dehydrogenase (quinone) activity
G5B40_RS03790	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G5B40_RS03825	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G5B40_RS03830	COG2814	Major facilitator Superfamily
G5B40_RS03835	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
G5B40_RS03840	COG0352	thiamine-phosphate diphosphorylase activity
G5B40_RS03850	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
G5B40_RS03895	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
G5B40_RS03900	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
G5B40_RS03905	COG3246	L-lysine catabolic process to acetate
G5B40_RS03910	COG0824	Thioesterase
G5B40_RS03910	COG1250	3-hydroxyacyl-CoA dehydrogenase
G5B40_RS03920	COG1960	acyl-CoA dehydrogenase activity
G5B40_RS03945	COG3773	Cell wall hydrolase
G5B40_RS03945	COG3409	Peptidoglycan-binding domain 1 protein
G5B40_RS03950	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G5B40_RS03950	COG0574	Belongs to the PEP-utilizing enzyme family
G5B40_RS03955	COG0751	glycine-tRNA ligase activity
G5B40_RS03965	COG0752	glycyl-tRNA synthetase alpha subunit
G5B40_RS04015	COG1692	metallophosphoesterase
G5B40_RS04020	COG0471	metal ion transport
G5B40_RS04020	COG3273	potassium ion transport
G5B40_RS04025	COG0217	transcriptional regulatory protein
G5B40_RS04035	COG0352	thiamine-phosphate diphosphorylase activity
G5B40_RS04060	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G5B40_RS04070	COG0395	ABC-type sugar transport system, permease component
G5B40_RS04075	COG1175	transmembrane transport
G5B40_RS04080	COG3842	ATPase activity
G5B40_RS04085	COG3842	ATPase activity
G5B40_RS04105	COG0729	surface antigen
G5B40_RS04115	COG3264	Mechanosensitive ion channel
G5B40_RS04115	COG1196	nuclear chromosome segregation
G5B40_RS04120	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G5B40_RS04125	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
G5B40_RS04130	COG2986	histidine ammonia-lyase
G5B40_RS04135	COG1228	amidohydrolase
G5B40_RS04165	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G5B40_RS04175	COG1136	(ABC) transporter
G5B40_RS04185	COG0442	prolyl-tRNA aminoacylation
G5B40_RS04205	COG0628	permease
G5B40_RS04215	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
G5B40_RS04225	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
G5B40_RS04240	COG1959	2 iron, 2 sulfur cluster binding
G5B40_RS04260	COG2258	MOSC domain
G5B40_RS04280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G5B40_RS04295	COG0778	Nitroreductase
G5B40_RS04305	COG0456	acetyltransferase
G5B40_RS04360	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
G5B40_RS04365	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
G5B40_RS04370	COG0589	response to stress
G5B40_RS04375	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
G5B40_RS04380	COG0433	COG0433 Predicted ATPase
G5B40_RS04400	COG2989	Protein conserved in bacteria
G5B40_RS04410	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
G5B40_RS04415	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
G5B40_RS04420	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
G5B40_RS04430	COG0211	Belongs to the bacterial ribosomal protein bL27 family
G5B40_RS04435	COG0261	This protein binds to 23S rRNA in the presence of protein L20
G5B40_RS04460	COG2983	Belongs to the UPF0260 family
G5B40_RS04475	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
G5B40_RS04500	COG0513	Belongs to the DEAD box helicase family
G5B40_RS04525	COG0204	Acyl-transferase
G5B40_RS04530	COG0318	PFAM AMP-dependent synthetase and ligase
G5B40_RS04580	COG0583	DNA-binding transcription factor activity
G5B40_RS04595	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
G5B40_RS04605	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
G5B40_RS04615	COG0492	ferredoxin-NADP+ reductase activity
G5B40_RS04655	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G5B40_RS04655	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G5B40_RS04665	COG2391	methyltransferase activity
G5B40_RS04675	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
G5B40_RS04680	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G5B40_RS04685	COG0402	S-adenosylhomocysteine deaminase activity
G5B40_RS04705	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
G5B40_RS04710	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
G5B40_RS04715	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
G5B40_RS04720	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
G5B40_RS04725	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
G5B40_RS04740	COG2204	response regulator
G5B40_RS04745	COG0784	Response regulator, receiver
G5B40_RS04745	COG2198	Histidine kinase
G5B40_RS04745	COG2205	protein histidine kinase activity
G5B40_RS04765	COG0745	RESPONSE REGULATOR receiver
G5B40_RS04775	COG0482	sulfurtransferase activity
G5B40_RS04780	COG0386	Belongs to the glutathione peroxidase family
G5B40_RS04805	COG1830	Aldolase
G5B40_RS04810	COG1028	Short-chain dehydrogenase reductase Sdr
G5B40_RS04815	COG0126	phosphoglycerate kinase activity
G5B40_RS04835	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
G5B40_RS04850	COG0625	glutathione transferase activity
G5B40_RS04885	COG3971	2-oxopent-4-enoate hydratase activity
G5B40_RS04890	COG0179	Fumarylacetoacetate (FAA) hydrolase
G5B40_RS04935	COG0287	Prephenate dehydrogenase
G5B40_RS04940	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G5B40_RS04950	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G5B40_RS04975	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G5B40_RS04990	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G5B40_RS05010	COG0318	PFAM AMP-dependent synthetase and ligase
G5B40_RS05020	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
G5B40_RS05025	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G5B40_RS05030	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
G5B40_RS05035	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
G5B40_RS05045	COG2890	protein-(glutamine-N5) methyltransferase activity
G5B40_RS05050	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
G5B40_RS05075	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
G5B40_RS05090	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
G5B40_RS05090	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
G5B40_RS05105	COG1404	Belongs to the peptidase S8 family
G5B40_RS05110	COG1473	amidohydrolase
G5B40_RS05130	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G5B40_RS05135	COG0006	proline dipeptidase activity
G5B40_RS05180	COG2133	pyrroloquinoline quinone binding
G5B40_RS05185	COG0113	porphobilinogen synthase activity
G5B40_RS05195	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
G5B40_RS05205	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G5B40_RS05210	COG0583	DNA-binding transcription factor activity
G5B40_RS05265	COG0747	negative chemotaxis
G5B40_RS05280	COG0601	transmembrane transport
G5B40_RS05290	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
G5B40_RS05295	COG1971	Probably functions as a manganese efflux pump
G5B40_RS05300	COG0308	aminopeptidase N
G5B40_RS05310	COG0123	including yeast histone deacetylase and acetoin utilization protein
G5B40_RS05315	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
G5B40_RS05320	COG1024	Enoyl-CoA hydratase
G5B40_RS05325	COG3088	subunit of a heme lyase
G5B40_RS05330	COG1138	Cytochrome C-type biogenesis protein
G5B40_RS05340	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
G5B40_RS05345	COG1295	ribonuclease BN
G5B40_RS05350	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
G5B40_RS05355	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
G5B40_RS05370	COG1522	sequence-specific DNA binding
G5B40_RS05375	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
G5B40_RS05385	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
G5B40_RS05390	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
G5B40_RS05410	COG0625	glutathione transferase activity
G5B40_RS05420	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G5B40_RS05425	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G5B40_RS05445	COG0583	DNA-binding transcription factor activity
G5B40_RS05450	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G5B40_RS05480	COG1285	pathogenesis
G5B40_RS05490	COG1522	sequence-specific DNA binding
G5B40_RS05495	COG1522	sequence-specific DNA binding
G5B40_RS05500	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
G5B40_RS05505	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
G5B40_RS05525	COG3265	gluconokinase activity
G5B40_RS05530	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G5B40_RS05570	COG4983	Phage plasmid primase, P4 family domain protein
G5B40_RS05595	COG0582	viral genome integration into host DNA
G5B40_RS05605	COG0583	DNA-binding transcription factor activity
G5B40_RS05620	COG0625	glutathione transferase activity
G5B40_RS05645	COG1175	transmembrane transport
G5B40_RS05660	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G5B40_RS05665	COG0191	fructose-bisphosphate aldolase activity
G5B40_RS05675	COG0546	phosphoglycolate phosphatase activity
G5B40_RS05685	COG3842	ATPase activity
G5B40_RS05695	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G5B40_RS05705	COG1879	ABC-type sugar transport system periplasmic component
G5B40_RS05710	COG1172	Belongs to the binding-protein-dependent transport system permease family
G5B40_RS05715	COG1172	Belongs to the binding-protein-dependent transport system permease family
G5B40_RS05725	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G5B40_RS05730	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G5B40_RS05740	COG4948	Mandelate Racemase Muconate Lactonizing
G5B40_RS05745	COG1082	Xylose isomerase domain protein TIM barrel
G5B40_RS05770	COG0673	inositol 2-dehydrogenase activity
G5B40_RS05805	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G5B40_RS05810	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
G5B40_RS05815	COG2124	cytochrome p450
G5B40_RS05830	COG0625	glutathione transferase activity
G5B40_RS05835	COG1595	DNA-templated transcription, initiation
G5B40_RS05875	COG2175	clavaminate synthase activity
G5B40_RS05910	COG0318	PFAM AMP-dependent synthetase and ligase
G5B40_RS05925	COG1028	Short-chain dehydrogenase reductase Sdr
G5B40_RS05930	COG1024	Enoyl-CoA hydratase
G5B40_RS05950	COG1960	acyl-CoA dehydrogenase activity
G5B40_RS05955	COG1960	acyl-CoA dehydrogenase activity
G5B40_RS05995	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G5B40_RS06005	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G5B40_RS06020	COG3618	amidohydrolase
G5B40_RS06045	COG1028	Short-chain dehydrogenase reductase Sdr
G5B40_RS06050	COG4221	oxidoreductase activity
G5B40_RS06055	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G5B40_RS06070	COG1024	Enoyl-CoA hydratase
G5B40_RS06080	COG1802	Transcriptional regulator
G5B40_RS06085	COG0511	ligase activity, forming carbon-carbon bonds
G5B40_RS06090	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G5B40_RS06095	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G5B40_RS06100	COG0439	Biotin carboxylase
G5B40_RS06120	COG0765	amino acid transport
G5B40_RS06125	COG0765	amino acid transport
G5B40_RS06130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G5B40_RS06155	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
G5B40_RS06165	COG0181	hydroxymethylbilane synthase activity
G5B40_RS06200	COG1959	2 iron, 2 sulfur cluster binding
G5B40_RS06205	COG2346	COG2346, Truncated hemoglobins
G5B40_RS06210	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
G5B40_RS06230	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
G5B40_RS06240	COG2070	2-Nitropropane dioxygenase
G5B40_RS06250	COG0436	Aminotransferase
G5B40_RS06270	COG4598	ABC transporter
G5B40_RS06275	COG0765	amino acid transport
G5B40_RS06280	COG0765	amino acid transport
G5B40_RS06285	COG4172	Belongs to the ABC transporter superfamily
G5B40_RS06295	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
G5B40_RS06300	COG1522	sequence-specific DNA binding
G5B40_RS06305	COG1228	amidohydrolase
G5B40_RS06320	COG0747	negative chemotaxis
G5B40_RS06345	COG1061	Type III restriction enzyme res subunit
G5B40_RS06355	COG0546	phosphoglycolate phosphatase activity
G5B40_RS06365	COG1063	alcohol dehydrogenase
G5B40_RS06370	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
G5B40_RS06400	COG1393	Belongs to the ArsC family
G5B40_RS06405	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G5B40_RS06435	COG0154	amidase activity
G5B40_RS06455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G5B40_RS06460	COG0601	transmembrane transport
G5B40_RS06465	COG0747	negative chemotaxis
G5B40_RS06470	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G5B40_RS06480	COG2943	transferase activity, transferring hexosyl groups
G5B40_RS06495	COG0438	transferase activity, transferring glycosyl groups
G5B40_RS06525	COG0404	The glycine cleavage system catalyzes the degradation of glycine
G5B40_RS06525	COG0446	pyridine nucleotide-disulphide oxidoreductase
G5B40_RS06540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G5B40_RS06545	COG4235	cytochrome complex assembly
G5B40_RS06550	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
G5B40_RS06570	COG0730	response to heat
G5B40_RS06575	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
G5B40_RS06600	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G5B40_RS06650	COG3119	arylsulfatase activity
G5B40_RS06675	COG0747	negative chemotaxis
G5B40_RS06705	COG0598	Magnesium transport protein CorA
G5B40_RS06715	COG0747	negative chemotaxis
G5B40_RS06755	COG3191	aminopeptidase activity
G5B40_RS06785	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G5B40_RS06790	COG1028	Short-chain dehydrogenase reductase Sdr
G5B40_RS06795	COG1802	Transcriptional regulator
G5B40_RS06800	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
G5B40_RS06805	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
G5B40_RS06830	COG2124	cytochrome p450
G5B40_RS06835	COG2814	Major facilitator Superfamily
G5B40_RS06855	COG0416	fatty acid biosynthetic process
G5B40_RS06860	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G5B40_RS06880	COG0717	Belongs to the dCTP deaminase family
G5B40_RS06890	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G5B40_RS06895	COG0154	amidase activity
G5B40_RS06900	COG1278	Cold shock
G5B40_RS06925	COG1442	glycosyl transferase family 8
G5B40_RS06925	COG1216	Glycosyl transferase, family 2
G5B40_RS06960	COG1024	Enoyl-CoA hydratase
G5B40_RS06965	COG1960	acyl-CoA dehydrogenase activity
G5B40_RS06975	COG1024	Enoyl-CoA hydratase
G5B40_RS06995	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G5B40_RS07005	COG1960	acyl-CoA dehydrogenase activity
G5B40_RS07010	COG1454	alcohol dehydrogenase
G5B40_RS07035	COG0196	riboflavin kinase activity
G5B40_RS07040	COG2030	dehydratase
G5B40_RS07055	COG0459	protein refolding
G5B40_RS07065	COG2066	Belongs to the glutaminase family
G5B40_RS07070	COG1073	alpha beta
G5B40_RS07075	COG0363	glucosamine-6-phosphate deaminase activity
G5B40_RS07080	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
G5B40_RS07095	COG1764	response to oxidative stress
G5B40_RS07105	COG0440	acetolactate synthase activity
G5B40_RS07110	COG0028	Belongs to the TPP enzyme family
G5B40_RS07115	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
G5B40_RS07120	COG1904	glucuronate isomerase
G5B40_RS07125	COG0246	Mannitol dehydrogenase
G5B40_RS07130	COG1312	Catalyzes the dehydration of D-mannonate
G5B40_RS07140	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G5B40_RS07145	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G5B40_RS07160	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
G5B40_RS07170	COG0583	DNA-binding transcription factor activity
G5B40_RS07240	COG2165	general secretion pathway protein
G5B40_RS07275	COG1450	Type ii and iii secretion system protein
G5B40_RS07280	COG1132	(ABC) transporter
G5B40_RS07320	COG3422	double-strand break repair
G5B40_RS07325	COG0418	dihydroorotase activity
G5B40_RS07340	COG0154	amidase activity
G5B40_RS07350	COG2226	methyltransferase
G5B40_RS07355	COG0450	alkyl hydroperoxide reductase
G5B40_RS07375	COG0792	nuclease activity
G5B40_RS07380	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
G5B40_RS07390	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
G5B40_RS07395	COG0728	peptidoglycan biosynthetic process
G5B40_RS07400	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G5B40_RS07420	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G5B40_RS07425	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
G5B40_RS07430	COG4106	trans-aconitate 2-methyltransferase activity
G5B40_RS07435	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G5B40_RS07440	COG0037	tRNA processing
G5B40_RS07450	COG2885	chlorophyll binding
G5B40_RS07475	COG0824	Thioesterase
G5B40_RS07490	COG2255	four-way junction helicase activity
G5B40_RS07495	COG0632	four-way junction helicase activity
G5B40_RS07500	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
G5B40_RS07510	COG2264	protein methyltransferase activity
G5B40_RS07520	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G5B40_RS07525	COG0210	DNA helicase
G5B40_RS07540	COG1671	Belongs to the UPF0178 family
G5B40_RS07575	COG0625	glutathione transferase activity
G5B40_RS07620	COG2084	Dehydrogenase
G5B40_RS07635	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G5B40_RS07650	COG0719	Fe-S assembly protein
G5B40_RS07655	COG0396	ATPase activity
G5B40_RS07665	COG0719	Fe-S assembly protein
G5B40_RS07680	COG2945	thiolester hydrolase activity
G5B40_RS07690	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
G5B40_RS07695	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
G5B40_RS07705	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G5B40_RS07710	COG2833	Protein of unknown function (DUF455)
G5B40_RS07715	COG1196	nuclear chromosome segregation
G5B40_RS07715	COG0741	lytic transglycosylase activity
G5B40_RS07715	COG0739	heme binding
G5B40_RS07745	COG2239	Acts as a magnesium transporter
G5B40_RS07750	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
G5B40_RS07760	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
G5B40_RS07775	COG1530	ribonuclease E activity
G5B40_RS07780	COG0514	ATP-dependent DNA helicase (RecQ)
G5B40_RS07810	COG0525	valine-tRNA ligase activity
G5B40_RS07825	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
G5B40_RS07830	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
G5B40_RS07835	COG3453	Protein conserved in bacteria
G5B40_RS07835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G5B40_RS07845	COG0105	UTP biosynthetic process
G5B40_RS07890	COG1766	The M ring may be actively involved in energy transduction
G5B40_RS07900	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
G5B40_RS07905	COG1338	Plays a role in the flagellum-specific transport system
G5B40_RS07910	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
G5B40_RS07915	COG1706	bacterial-type flagellum-dependent cell motility
G5B40_RS07935	COG1360	Flagellar Motor Protein
G5B40_RS07945	COG0291	Belongs to the bacterial ribosomal protein bL35 family
G5B40_RS07950	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
G5B40_RS07960	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
G5B40_RS07970	COG0473	3-isopropylmalate dehydrogenase activity
G5B40_RS07990	COG3038	cytochrome b561
G5B40_RS08005	COG2353	YceI-like domain
G5B40_RS08010	COG1250	3-hydroxyacyl-CoA dehydrogenase
G5B40_RS08035	COG0668	transmembrane transport
G5B40_RS08050	COG2096	Adenosyltransferase
G5B40_RS08065	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
G5B40_RS08070	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
G5B40_RS08075	COG2364	Membrane
G5B40_RS08120	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G5B40_RS08135	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
G5B40_RS08150	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
G5B40_RS08160	COG0228	four-way junction DNA binding
G5B40_RS08165	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
G5B40_RS08175	COG0335	large ribosomal subunit rRNA binding
G5B40_RS08185	COG2116	formate transmembrane transporter activity
G5B40_RS08195	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G5B40_RS08240	COG1522	sequence-specific DNA binding
G5B40_RS08245	COG0492	ferredoxin-NADP+ reductase activity
G5B40_RS08255	COG1570	exodeoxyribonuclease VII activity
G5B40_RS08275	COG1396	sequence-specific DNA binding
G5B40_RS08280	COG0483	inositol monophosphate 1-phosphatase activity
G5B40_RS08300	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
G5B40_RS08305	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
G5B40_RS08310	COG1329	Transcriptional regulator
G5B40_RS08315	COG3608	succinylglutamate desuccinylase aspartoacylase
G5B40_RS08320	COG0006	proline dipeptidase activity
G5B40_RS08325	COG2423	ornithine cyclodeaminase activity
G5B40_RS08330	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
G5B40_RS08335	COG0589	response to stress
G5B40_RS08340	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G5B40_RS08345	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
G5B40_RS08350	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G5B40_RS08355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G5B40_RS08360	COG1522	sequence-specific DNA binding
G5B40_RS08365	COG1012	belongs to the aldehyde dehydrogenase family
G5B40_RS08370	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G5B40_RS08380	COG2721	sulfolactate sulfo-lyase activity
G5B40_RS08390	COG3622	Belongs to the hyi family
G5B40_RS08395	COG0235	Class ii aldolase
G5B40_RS08400	COG3395	kinase activity
G5B40_RS08405	COG2084	Dehydrogenase
G5B40_RS08410	COG0678	peroxiredoxin activity
G5B40_RS08415	COG0742	ribosomal rna small subunit methyltransferase
G5B40_RS08420	COG0604	alcohol dehydrogenase
G5B40_RS08430	COG2267	carboxylic ester hydrolase activity
G5B40_RS08445	COG3237	CsbD-like
G5B40_RS08455	COG1309	transcriptional regulator
G5B40_RS08465	COG0254	rRNA binding
G5B40_RS08470	COG1192	Involved in chromosome partitioning
G5B40_RS08475	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
G5B40_RS08480	COG1686	Belongs to the peptidase S11 family
G5B40_RS08490	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
G5B40_RS08525	COG0483	inositol monophosphate 1-phosphatase activity
G5B40_RS08535	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
G5B40_RS08560	COG2010	Cytochrome c
G5B40_RS08575	COG1872	DUF167
G5B40_RS08595	COG0137	argininosuccinate synthase activity
G5B40_RS08600	COG1028	Short-chain dehydrogenase reductase Sdr
G5B40_RS08605	COG3964	amidohydrolase
G5B40_RS08625	COG0318	PFAM AMP-dependent synthetase and ligase
G5B40_RS08645	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G5B40_RS08690	COG4948	Mandelate Racemase Muconate Lactonizing
G5B40_RS08695	COG1802	Transcriptional regulator
G5B40_RS08700	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G5B40_RS08720	COG0444	Belongs to the ABC transporter superfamily
G5B40_RS08740	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G5B40_RS08755	COG1968	undecaprenyl-diphosphatase activity
G5B40_RS08785	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G5B40_RS08795	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
G5B40_RS08815	COG0789	Transcriptional regulator
G5B40_RS08825	COG0321	lipoyl(octanoyl) transferase activity
G5B40_RS08865	COG3119	arylsulfatase activity
G5B40_RS08875	COG0601	transmembrane transport
G5B40_RS08890	COG4608	Belongs to the ABC transporter superfamily
G5B40_RS08895	COG0697	spore germination
G5B40_RS08905	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
G5B40_RS08920	COG0556	nucleotide-excision repair
G5B40_RS08945	COG1181	Belongs to the D-alanine--D-alanine ligase family
G5B40_RS08950	COG1982	Orn Lys Arg decarboxylase major
G5B40_RS08970	COG2358	TRAP transporter, solute receptor (TAXI family
G5B40_RS08975	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G5B40_RS08990	COG0825	malonyl-CoA metabolic process
G5B40_RS09005	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
G5B40_RS09020	COG0616	signal peptide processing
G5B40_RS09020	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G5B40_RS09045	COG0322	excinuclease ABC activity
G5B40_RS09060	COG4608	Belongs to the ABC transporter superfamily
G5B40_RS09070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G5B40_RS09075	COG0601	transmembrane transport
G5B40_RS09090	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
G5B40_RS09110	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G5B40_RS09120	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G5B40_RS09140	COG0437	4 iron, 4 sulfur cluster binding
G5B40_RS09145	COG3383	formate dehydrogenase (NAD+) activity
G5B40_RS09145	COG0243	molybdopterin cofactor binding
G5B40_RS09180	COG0489	protein tyrosine kinase activity
G5B40_RS09195	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G5B40_RS09200	COG0662	Cupin 2, conserved barrel domain protein
G5B40_RS09200	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
G5B40_RS09205	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
G5B40_RS09210	COG0438	transferase activity, transferring glycosyl groups
G5B40_RS09225	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
G5B40_RS09235	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
G5B40_RS09240	COG0022	dehydrogenase e1 component
G5B40_RS09245	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G5B40_RS09260	COG0028	Belongs to the TPP enzyme family
G5B40_RS09270	COG1414	Transcriptional regulator
G5B40_RS09285	COG0848	biopolymer transport protein
G5B40_RS09290	COG0811	peptide transport
G5B40_RS09300	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
G5B40_RS09305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G5B40_RS09320	COG0411	ABC transporter
G5B40_RS09385	COG0165	Argininosuccinate lyase
G5B40_RS09390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G5B40_RS09400	COG0154	amidase activity
G5B40_RS09410	COG0583	DNA-binding transcription factor activity
G5B40_RS09415	COG0546	phosphoglycolate phosphatase activity
G5B40_RS09480	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G5B40_RS09500	COG2084	Dehydrogenase
G5B40_RS09505	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
G5B40_RS09515	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G5B40_RS09550	COG1522	sequence-specific DNA binding
G5B40_RS09555	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
G5B40_RS09580	COG1802	Transcriptional regulator
G5B40_RS09610	COG1012	belongs to the aldehyde dehydrogenase family
G5B40_RS09615	COG0252	asparaginase activity
G5B40_RS09645	COG0628	permease
G5B40_RS09680	COG0783	Belongs to the Dps family
G5B40_RS09710	COG0784	Response regulator, receiver
G5B40_RS09735	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
G5B40_RS09740	COG2943	transferase activity, transferring hexosyl groups
G5B40_RS09745	COG3360	Dodecin
G5B40_RS09750	COG3246	L-lysine catabolic process to acetate
G5B40_RS09755	COG3485	protocatechuate 3,4-dioxygenase
G5B40_RS09760	COG3485	protocatechuate 3,4-dioxygenase
G5B40_RS09765	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G5B40_RS09770	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G5B40_RS09785	COG0180	Tryptophanyl-tRNA synthetase
G5B40_RS09795	COG0069	glutamate synthase activity
G5B40_RS09805	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G5B40_RS09810	COG1058	Belongs to the CinA family
G5B40_RS09810	COG1546	Belongs to the CinA family
G5B40_RS09815	COG0024	Methionine aminopeptidase
G5B40_RS09850	COG3903	Transcriptional regulator
G5B40_RS09850	COG3629	intracellular signal transduction
G5B40_RS09865	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G5B40_RS09875	COG0072	phenylalanine-tRNA ligase activity
G5B40_RS09875	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G5B40_RS09880	COG1970	mechanosensitive ion channel activity
G5B40_RS09890	COG1294	oxidase, subunit
G5B40_RS09895	COG1271	oxidase subunit
G5B40_RS09900	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
G5B40_RS09905	COG0746	molybdenum cofactor guanylyltransferase activity
G5B40_RS09910	COG1763	Mo-molybdopterin cofactor biosynthetic process
G5B40_RS09915	COG0303	'Molybdopterin
G5B40_RS09925	COG2003	Belongs to the UPF0758 family
G5B40_RS09930	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G5B40_RS09945	COG2081	HI0933 family
G5B40_RS09950	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G5B40_RS09955	COG1473	amidohydrolase
G5B40_RS09960	COG1473	amidohydrolase
G5B40_RS09965	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G5B40_RS09990	COG1960	acyl-CoA dehydrogenase activity
G5B40_RS10020	COG3618	amidohydrolase
G5B40_RS10025	COG5598	trimethylamine methyltransferase
G5B40_RS10030	COG0129	dihydroxy-acid dehydratase activity
G5B40_RS10045	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
G5B40_RS10050	COG2226	methyltransferase
G5B40_RS10055	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
G5B40_RS10060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G5B40_RS10075	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
G5B40_RS10085	COG1522	sequence-specific DNA binding
G5B40_RS10100	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
G5B40_RS10110	COG0481	GTPase activity
G5B40_RS10155	COG0159	tryptophan synthase activity
G5B40_RS10165	COG0133	tryptophan synthase activity
G5B40_RS10185	COG0135	phosphoribosylanthranilate isomerase activity
G5B40_RS10195	COG0776	regulation of translation
G5B40_RS10215	COG3386	PFAM SMP-30 Gluconolaconase
G5B40_RS10220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G5B40_RS10270	COG2268	Band 7 protein
G5B40_RS10275	COG5564	TIM-barrel signal transduction protein
G5B40_RS10280	COG5441	Belongs to the UPF0261 family
G5B40_RS10295	COG0559	Belongs to the binding-protein-dependent transport system permease family
G5B40_RS10315	COG1028	Short-chain dehydrogenase reductase Sdr
G5B40_RS10370	COG4221	oxidoreductase activity
G5B40_RS10375	COG0156	8-amino-7-oxononanoate synthase activity
G5B40_RS10380	COG0604	alcohol dehydrogenase
G5B40_RS10380	COG1028	Short-chain dehydrogenase reductase Sdr
G5B40_RS10380	COG3321	synthase
G5B40_RS10385	COG0438	transferase activity, transferring glycosyl groups
G5B40_RS10385	COG1216	Glycosyl transferase, family 2
G5B40_RS10410	COG0166	Belongs to the GPI family
G5B40_RS10415	COG0800	Aldolase
G5B40_RS10430	COG3850	Histidine kinase
G5B40_RS10430	COG5002	protein histidine kinase activity
G5B40_RS10435	COG5002	protein histidine kinase activity
G5B40_RS10460	COG0004	ammonium transporteR
G5B40_RS10465	COG0347	Belongs to the P(II) protein family
G5B40_RS10470	COG0519	Catalyzes the synthesis of GMP from XMP
G5B40_RS10470	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G5B40_RS10475	COG0583	DNA-binding transcription factor activity
G5B40_RS10485	COG1028	Short-chain dehydrogenase reductase Sdr
G5B40_RS10500	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
G5B40_RS10510	COG2818	Glycosylase
G5B40_RS10515	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G5B40_RS10545	COG0183	Belongs to the thiolase family
G5B40_RS10550	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
G5B40_RS10560	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G5B40_RS10570	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
G5B40_RS10575	COG1218	3'(2'),5'-bisphosphate nucleotidase
G5B40_RS10585	COG1280	lysine exporter protein (LysE YggA)
G5B40_RS10590	COG1846	Transcriptional regulator
G5B40_RS10595	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G5B40_RS10605	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
G5B40_RS10650	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
G5B40_RS10675	COG2351	hydroxyisourate hydrolase activity
G5B40_RS10685	COG3257	ureidoglycine aminohydrolase activity
G5B40_RS10690	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
G5B40_RS10700	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G5B40_RS10705	COG1183	phosphatidylcholine synthase activity
G5B40_RS10710	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
G5B40_RS10725	COG2995	paraquat-inducible protein a
G5B40_RS10730	COG2995	paraquat-inducible protein a
G5B40_RS10735	COG3008	intermembrane lipid transfer
G5B40_RS10750	COG2885	chlorophyll binding
G5B40_RS10750	COG3047	cAMP biosynthetic process
G5B40_RS10770	COG0268	Binds directly to 16S ribosomal RNA
G5B40_RS10775	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G5B40_RS10785	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G5B40_RS10790	COG1902	pentaerythritol trinitrate reductase activity
G5B40_RS10815	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
G5B40_RS10825	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
G5B40_RS10830	COG1385	rRNA (uridine-N3-)-methyltransferase activity
G5B40_RS10850	COG0267	Belongs to the bacterial ribosomal protein bL33 family
G5B40_RS10875	COG1595	DNA-templated transcription, initiation
G5B40_RS10890	COG5001	Diguanylate cyclase
G5B40_RS10890	COG4251	negative regulation of phosphorylation
G5B40_RS10890	COG3706	GGDEF domain
G5B40_RS10890	COG2203	Gaf domain
G5B40_RS10895	COG2204	response regulator
G5B40_RS10915	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
G5B40_RS10930	COG3971	2-oxopent-4-enoate hydratase activity
G5B40_RS10945	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G5B40_RS10965	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G5B40_RS10980	COG2186	Transcriptional regulator
G5B40_RS10990	COG0765	amino acid transport
G5B40_RS10995	COG4597	amino acid ABC transporter
G5B40_RS11000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G5B40_RS11015	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
G5B40_RS11020	COG1132	(ABC) transporter
G5B40_RS11025	COG0438	transferase activity, transferring glycosyl groups
G5B40_RS11045	COG0463	Glycosyl transferase, family 2
G5B40_RS11050	COG1215	transferase activity, transferring glycosyl groups
G5B40_RS11070	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G5B40_RS11070	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G5B40_RS11080	COG4770	biotin carboxylase activity
G5B40_RS11115	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G5B40_RS11160	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
G5B40_RS11160	COG3264	Mechanosensitive ion channel
G5B40_RS11165	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G5B40_RS11175	COG4221	oxidoreductase activity
G5B40_RS11180	COG0446	pyridine nucleotide-disulphide oxidoreductase
G5B40_RS11180	COG1902	pentaerythritol trinitrate reductase activity
G5B40_RS11195	COG2211	Major facilitator Superfamily
G5B40_RS11200	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G5B40_RS11215	COG0415	Belongs to the DNA photolyase family
G5B40_RS11225	COG0179	Fumarylacetoacetate (FAA) hydrolase
G5B40_RS11230	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
G5B40_RS11235	COG0405	Gamma-glutamyltransferase
G5B40_RS11250	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G5B40_RS11255	COG1435	thymidine kinase activity
G5B40_RS11265	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
G5B40_RS11270	COG1214	PFAM Peptidase M22, glycoprotease
G5B40_RS11295	COG0714	Associated with various cellular activities
G5B40_RS11315	COG0617	tRNA 3'-terminal CCA addition
G5B40_RS11320	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
G5B40_RS11330	COG1335	isochorismatase
G5B40_RS11340	COG0559	Belongs to the binding-protein-dependent transport system permease family
G5B40_RS11360	COG1335	isochorismatase
G5B40_RS11375	COG0174	glutamine synthetase
G5B40_RS11390	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G5B40_RS11405	COG1378	Sugar-specific transcriptional regulator TrmB
G5B40_RS11415	COG1012	belongs to the aldehyde dehydrogenase family
G5B40_RS11440	COG0596	Alpha beta hydrolase
G5B40_RS11455	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G5B40_RS11460	COG0028	Belongs to the TPP enzyme family
G5B40_RS11465	COG1028	Short-chain dehydrogenase reductase Sdr
G5B40_RS11490	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
G5B40_RS11530	COG2010	Cytochrome c
G5B40_RS11650	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
G5B40_RS11660	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G5B40_RS11665	COG0583	DNA-binding transcription factor activity
G5B40_RS11675	COG1960	acyl-CoA dehydrogenase activity
G5B40_RS11680	COG1024	Enoyl-CoA hydratase
G5B40_RS11685	COG1177	transmembrane transport
G5B40_RS11690	COG1176	ABC-type spermidine putrescine transport system, permease component I
G5B40_RS11695	COG3842	ATPase activity
G5B40_RS11700	COG1840	ABC-type Fe3 transport system, periplasmic component
G5B40_RS11705	COG2072	flavoprotein involved in K transport
G5B40_RS11720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G5B40_RS11735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G5B40_RS11740	COG0601	transmembrane transport
G5B40_RS11745	COG0747	negative chemotaxis
G5B40_RS11755	COG4221	oxidoreductase activity
G5B40_RS11770	COG1619	proteins homologs of microcin C7 resistance protein MccF
G5B40_RS11785	COG0658	competence protein
G5B40_RS11785	COG2333	competence protein COMEC
G5B40_RS11790	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G5B40_RS11795	COG0372	Belongs to the citrate synthase family
G5B40_RS11805	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
G5B40_RS11815	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G5B40_RS11820	COG0750	zinc metalloprotease
G5B40_RS11825	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
G5B40_RS11835	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
G5B40_RS11840	COG0233	cytoplasmic translational termination
G5B40_RS11845	COG0528	UMP kinase activity
G5B40_RS11855	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
G5B40_RS11860	COG0052	Belongs to the universal ribosomal protein uS2 family
G5B40_RS11870	COG2313	pseudouridylate synthase activity
G5B40_RS11910	COG1846	Transcriptional regulator
G5B40_RS11915	COG0606	chelatase, subunit chli
G5B40_RS11935	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
G5B40_RS11950	COG3152	Membrane
G5B40_RS11960	COG3853	Toxic anion resistance protein (TelA)
G5B40_RS11980	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G5B40_RS11980	COG0425	Belongs to the sulfur carrier protein TusA family
G5B40_RS11985	COG0193	aminoacyl-tRNA hydrolase activity
G5B40_RS11990	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
G5B40_RS12015	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G5B40_RS12025	COG2084	Dehydrogenase
G5B40_RS12035	COG4948	Mandelate Racemase Muconate Lactonizing
G5B40_RS12050	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
G5B40_RS12060	COG0183	Belongs to the thiolase family
G5B40_RS12065	COG1024	Enoyl-CoA hydratase
G5B40_RS12065	COG1250	3-hydroxyacyl-CoA dehydrogenase
G5B40_RS12090	COG4957	zinc ion binding
G5B40_RS12095	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G5B40_RS12105	COG0028	Belongs to the TPP enzyme family
G5B40_RS12120	COG1011	Hydrolase
G5B40_RS12130	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G5B40_RS12135	COG1744	ABC transporter substrate-binding protein PnrA-like
G5B40_RS12210	COG3263	regulation of cellular component size
G5B40_RS12215	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
G5B40_RS12225	COG2733	membrane
G5B40_RS12235	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G5B40_RS12275	COG4221	oxidoreductase activity
G5B40_RS12280	COG0747	negative chemotaxis
G5B40_RS12290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G5B40_RS12295	COG4172	Belongs to the ABC transporter superfamily
G5B40_RS12300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G5B40_RS12310	COG1473	amidohydrolase
G5B40_RS12360	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
G5B40_RS12365	COG0438	transferase activity, transferring glycosyl groups
G5B40_RS12370	COG0489	protein tyrosine kinase activity
G5B40_RS12370	COG3206	protein involved in exopolysaccharide biosynthesis
G5B40_RS12375	COG2223	nitrite transmembrane transporter activity
G5B40_RS12380	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
G5B40_RS12385	COG1140	nitrate reductase beta subunit
G5B40_RS12390	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
G5B40_RS12395	COG2181	nitrate reductase activity
G5B40_RS12400	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G5B40_RS12420	COG0302	gtp cyclohydrolase
G5B40_RS12430	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
G5B40_RS12435	COG2721	sulfolactate sulfo-lyase activity
G5B40_RS12440	COG2721	sulfolactate sulfo-lyase activity
G5B40_RS12455	COG2721	sulfolactate sulfo-lyase activity
G5B40_RS12460	COG3181	Tripartite tricarboxylate transporter family receptor
G5B40_RS12500	COG2897	thiosulfate sulfurtransferase activity
G5B40_RS12515	COG3135	benzoate transporter
G5B40_RS12530	COG0463	Glycosyl transferase, family 2
G5B40_RS12535	COG1250	3-hydroxyacyl-CoA dehydrogenase
G5B40_RS12535	COG1024	Enoyl-CoA hydratase
G5B40_RS12540	COG0183	Belongs to the thiolase family
G5B40_RS12550	COG1960	acyl-CoA dehydrogenase activity
G5B40_RS12555	COG1960	acyl-CoA dehydrogenase activity
G5B40_RS12575	COG0534	Mate efflux family protein
G5B40_RS12585	COG0312	modulator of DNA gyrase
G5B40_RS12605	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
G5B40_RS12610	COG1335	isochorismatase
G5B40_RS12620	COG4638	Rieske (2fe-2S)
G5B40_RS12635	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G5B40_RS12640	COG0312	modulator of DNA gyrase
G5B40_RS12650	COG0109	protoheme IX farnesyltransferase activity
G5B40_RS12660	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
G5B40_RS12695	COG0625	glutathione transferase activity
G5B40_RS12715	COG4977	sequence-specific DNA binding
G5B40_RS12720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G5B40_RS12735	COG0446	pyridine nucleotide-disulphide oxidoreductase
G5B40_RS12735	COG0404	The glycine cleavage system catalyzes the degradation of glycine
G5B40_RS12760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G5B40_RS12765	COG4215	(ABC) transporter
G5B40_RS12770	COG0765	amino acid transport
G5B40_RS12775	COG0765	amino acid transport
G5B40_RS12780	COG1126	abc transporter atp-binding protein
G5B40_RS12790	COG3214	Protein conserved in bacteria
G5B40_RS12805	COG0174	glutamine synthetase
G5B40_RS12810	COG0010	Belongs to the arginase family
G5B40_RS12825	COG0154	amidase activity
G5B40_RS12830	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G5B40_RS12840	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G5B40_RS12850	COG1194	a g-specific adenine glycosylase
G5B40_RS12860	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
G5B40_RS12865	COG0247	lactate metabolic process
G5B40_RS12870	COG1139	Iron-sulfur cluster binding protein
G5B40_RS12875	COG1556	Lactate utilization protein
G5B40_RS12885	COG0708	Exodeoxyribonuclease III
G5B40_RS12890	COG0745	RESPONSE REGULATOR receiver
G5B40_RS12905	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
G5B40_RS12925	COG0495	leucyl-tRNA aminoacylation
G5B40_RS12950	COG0357	Ribosomal RNA small subunit methyltransferase G
G5B40_RS12955	COG0445	tRNA wobble uridine modification
G5B40_RS12960	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
G5B40_RS12970	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
G5B40_RS12980	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
G5B40_RS12985	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
G5B40_RS12990	COG0424	maF-like protein
G5B40_RS12995	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G5B40_RS13000	COG0237	dephospho-CoA kinase activity
G5B40_RS13005	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G5B40_RS13010	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
G5B40_RS13015	COG3030	protein affecting phage T7 exclusion by the F plasmid
G5B40_RS13040	COG2084	Dehydrogenase
G5B40_RS13050	COG1028	Short-chain dehydrogenase reductase Sdr
G5B40_RS13080	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
G5B40_RS13090	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G5B40_RS13115	COG0824	Thioesterase
G5B40_RS13120	COG0406	alpha-ribazole phosphatase activity
G5B40_RS13130	COG1091	dTDP-4-dehydrorhamnose reductase activity
G5B40_RS13135	COG1088	dTDP-glucose 4,6-dehydratase activity
G5B40_RS13140	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
G5B40_RS13145	COG0179	Fumarylacetoacetate (FAA) hydrolase
G5B40_RS13155	COG1024	Enoyl-CoA hydratase
G5B40_RS13155	COG1250	3-hydroxyacyl-CoA dehydrogenase
G5B40_RS13185	COG0546	phosphoglycolate phosphatase activity
G5B40_RS13210	COG0318	PFAM AMP-dependent synthetase and ligase
G5B40_RS13215	COG0028	Belongs to the TPP enzyme family
G5B40_RS13220	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
G5B40_RS13240	COG0154	amidase activity
G5B40_RS13250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G5B40_RS13255	COG0601	transmembrane transport
G5B40_RS13260	COG0747	negative chemotaxis
G5B40_RS13270	COG0489	protein tyrosine kinase activity
G5B40_RS13285	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
G5B40_RS13290	COG0142	geranyltranstransferase activity
G5B40_RS13295	COG1722	exodeoxyribonuclease VII activity
G5B40_RS13300	COG0123	including yeast histone deacetylase and acetoin utilization protein
G5B40_RS13305	COG0745	RESPONSE REGULATOR receiver
G5B40_RS13310	COG1846	Transcriptional regulator
G5B40_RS13325	COG0799	negative regulation of ribosome biogenesis
G5B40_RS13330	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
G5B40_RS13335	COG1902	pentaerythritol trinitrate reductase activity
G5B40_RS13340	COG1024	Enoyl-CoA hydratase
G5B40_RS13350	COG0546	phosphoglycolate phosphatase activity
G5B40_RS13360	COG0745	RESPONSE REGULATOR receiver
G5B40_RS13365	COG2205	protein histidine kinase activity
G5B40_RS13385	COG2239	Acts as a magnesium transporter
G5B40_RS13395	COG3768	UPF0283 membrane protein
G5B40_RS13400	COG3106	COG3106 Predicted ATPase
G5B40_RS13405	COG0101	tRNA pseudouridine synthase activity
G5B40_RS13410	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
G5B40_RS13415	COG1741	Belongs to the pirin family
G5B40_RS13440	COG2130	NADP-dependent
G5B40_RS13445	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
G5B40_RS13445	COG1672	PFAM Archaeal ATPase
G5B40_RS13455	COG2080	2 iron, 2 sulfur cluster binding
G5B40_RS13460	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G5B40_RS13500	COG1024	Enoyl-CoA hydratase
G5B40_RS13505	COG1960	acyl-CoA dehydrogenase activity
G5B40_RS13510	COG1960	acyl-CoA dehydrogenase activity
G5B40_RS13515	COG0183	Belongs to the thiolase family
G5B40_RS13520	COG1028	Short-chain dehydrogenase reductase Sdr
G5B40_RS13535	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
G5B40_RS13540	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
G5B40_RS13550	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
G5B40_RS13560	COG0667	Aldo Keto reductase
G5B40_RS13595	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G5B40_RS13620	COG1215	transferase activity, transferring glycosyl groups
G5B40_RS13625	COG0505	Belongs to the CarA family
G5B40_RS13665	COG4133	protoheme IX ABC transporter activity
G5B40_RS13670	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G5B40_RS13680	COG0515	serine threonine protein kinase
G5B40_RS13680	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G5B40_RS13685	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G5B40_RS13695	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G5B40_RS13705	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G5B40_RS13710	COG1959	2 iron, 2 sulfur cluster binding
G5B40_RS13715	COG0756	dUTP diphosphatase activity
G5B40_RS13720	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
G5B40_RS13730	COG0300	oxidoreductase activity
G5B40_RS13750	COG0408	coproporphyrinogen oxidase activity
G5B40_RS13755	COG1132	(ABC) transporter
G5B40_RS13765	COG1132	(ABC) transporter
G5B40_RS13795	COG2205	protein histidine kinase activity
G5B40_RS13820	COG0318	PFAM AMP-dependent synthetase and ligase
G5B40_RS13830	COG0670	Belongs to the BI1 family
G5B40_RS13840	COG4181	ATPase activity
G5B40_RS13850	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
G5B40_RS13860	COG0583	DNA-binding transcription factor activity
G5B40_RS13865	COG2759	Belongs to the formate--tetrahydrofolate ligase family
G5B40_RS13880	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
G5B40_RS13885	COG2951	lytic endotransglycosylase activity
G5B40_RS13890	COG0791	NLP P60 protein
G5B40_RS13895	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
G5B40_RS13905	COG1028	Short-chain dehydrogenase reductase Sdr
G5B40_RS13915	COG1063	alcohol dehydrogenase
G5B40_RS13925	COG1028	Short-chain dehydrogenase reductase Sdr
G5B40_RS13935	COG0820	rRNA (adenine-C2-)-methyltransferase activity
G5B40_RS13955	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G5B40_RS13975	COG0129	dihydroxy-acid dehydratase activity
G5B40_RS13990	COG4948	Mandelate Racemase Muconate Lactonizing
G5B40_RS14010	COG2046	Belongs to the sulfate adenylyltransferase family
G5B40_RS14010	COG0529	Catalyzes the synthesis of activated sulfate
G5B40_RS14025	COG0625	glutathione transferase activity
G5B40_RS14030	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
G5B40_RS14035	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
G5B40_RS14045	COG0012	GTP binding
G5B40_RS14055	COG0785	Cytochrome C biogenesis protein
G5B40_RS14065	COG2321	neutral zinc metallopeptidase
G5B40_RS14070	COG0114	fumarate hydratase activity
G5B40_RS14095	COG0346	lactoylglutathione lyase activity
G5B40_RS14100	COG2072	flavoprotein involved in K transport
G5B40_RS14105	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
G5B40_RS14180	COG2358	TRAP transporter, solute receptor (TAXI family
G5B40_RS14190	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G5B40_RS14195	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G5B40_RS14210	COG1028	Short-chain dehydrogenase reductase Sdr
G5B40_RS14225	COG3335	DDE superfamily endonuclease
G5B40_RS14230	COG3415	Transposase
G5B40_RS14315	COG1061	Type III restriction enzyme res subunit
G5B40_RS14355	COG1475	DNA binding
G5B40_RS14510	COG0531	amino acid
G5B40_RS14515	COG0398	Pfam SNARE associated Golgi protein
G5B40_RS14525	COG2132	Multicopper oxidase
G5B40_RS14535	COG3258	Cytochrome c
G5B40_RS14545	COG2217	Heavy metal translocating P-type atpase
G5B40_RS14550	COG0789	Transcriptional regulator
G5B40_RS14585	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
G5B40_RS14595	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G5B40_RS14625	COG0330	HflC and HflK could
G5B40_RS14670	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
G5B40_RS14675	COG0515	serine threonine protein kinase
G5B40_RS14675	COG2815	serine threonine protein kinase
G5B40_RS14750	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G5B40_RS14790	COG3457	Alanine racemase
G5B40_RS14845	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
G5B40_RS14855	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G5B40_RS14860	COG1121	(ABC) transporter
G5B40_RS14865	COG0735	belongs to the Fur family
G5B40_RS14880	COG0523	cobalamin synthesis protein
G5B40_RS14895	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G5B40_RS14900	COG0045	succinate-CoA ligase (ADP-forming) activity
G5B40_RS14900	COG1042	CoA-binding domain protein
G5B40_RS14900	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G5B40_RS14920	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
G5B40_RS14930	COG1802	Transcriptional regulator
G5B40_RS14935	COG0154	amidase activity
G5B40_RS14940	COG0747	negative chemotaxis
G5B40_RS14960	COG4608	Belongs to the ABC transporter superfamily
G5B40_RS14965	COG1335	isochorismatase
G5B40_RS14990	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
G5B40_RS14995	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G5B40_RS15000	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
G5B40_RS15005	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G5B40_RS15010	COG0154	amidase activity
G5B40_RS15055	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G5B40_RS15085	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G5B40_RS15090	COG2188	Transcriptional regulator
G5B40_RS15110	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G5B40_RS15125	COG1349	DNA-binding transcription factor activity
G5B40_RS15140	COG4172	Belongs to the ABC transporter superfamily
G5B40_RS15205	COG1518	maintenance of DNA repeat elements
G5B40_RS15255	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G5B40_RS15265	COG5598	trimethylamine methyltransferase
G5B40_RS15300	COG2193	ferroxidase activity
G5B40_RS15310	COG0318	PFAM AMP-dependent synthetase and ligase
G5B40_RS15340	COG1024	Enoyl-CoA hydratase
G5B40_RS15350	COG1960	acyl-CoA dehydrogenase activity
G5B40_RS15365	COG1850	ribulose-bisphosphate carboxylase activity
G5B40_RS15375	COG2186	Transcriptional regulator
G5B40_RS15385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G5B40_RS15390	COG1132	(ABC) transporter
G5B40_RS15395	COG2274	protein secretion by the type I secretion system
G5B40_RS15415	COG2201	protein-glutamate methylesterase activity
G5B40_RS15425	COG0745	RESPONSE REGULATOR receiver
G5B40_RS15430	COG5002	protein histidine kinase activity
G5B40_RS15440	COG0402	S-adenosylhomocysteine deaminase activity
G5B40_RS15480	COG0318	PFAM AMP-dependent synthetase and ligase
G5B40_RS15485	COG4221	oxidoreductase activity
G5B40_RS15515	COG1024	Enoyl-CoA hydratase
G5B40_RS15530	COG2186	Transcriptional regulator
G5B40_RS15560	COG0604	alcohol dehydrogenase
G5B40_RS15575	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G5B40_RS15580	COG0387	Pfam Sodium calcium exchanger
G5B40_RS15585	COG2985	domain, Protein
G5B40_RS15590	COG2985	domain, Protein
G5B40_RS15620	COG0628	permease
G5B40_RS15650	COG0402	S-adenosylhomocysteine deaminase activity
G5B40_RS15655	COG0747	negative chemotaxis
G5B40_RS15660	COG0601	transmembrane transport
G5B40_RS15665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G5B40_RS15670	COG0444	Belongs to the ABC transporter superfamily
G5B40_RS15675	COG4608	Belongs to the ABC transporter superfamily
G5B40_RS15705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G5B40_RS15735	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G5B40_RS15745	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G5B40_RS15775	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
G5B40_RS15780	COG1984	allophanate hydrolase subunit 2
G5B40_RS15810	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G5B40_RS15830	COG4336	lyase activity
G5B40_RS15835	COG0395	ABC-type sugar transport system, permease component
G5B40_RS15840	COG1175	transmembrane transport
G5B40_RS15870	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
G5B40_RS15875	COG3639	organic phosphonate transmembrane transporter activity
G5B40_RS15900	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G5B40_RS15910	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G5B40_RS15915	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
G5B40_RS15920	COG0247	lactate metabolic process
G5B40_RS15920	COG0277	FAD linked oxidase domain protein
G5B40_RS15925	COG1802	Transcriptional regulator
G5B40_RS15930	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G5B40_RS15985	COG1028	Short-chain dehydrogenase reductase Sdr
G5B40_RS15990	COG1250	3-hydroxyacyl-CoA dehydrogenase
G5B40_RS15990	COG1024	Enoyl-CoA hydratase
G5B40_RS16000	COG2264	protein methyltransferase activity
G5B40_RS16005	COG1696	Membrane protein involved in D-alanine export
G5B40_RS16030	COG0779	Required for maturation of 30S ribosomal subunits
G5B40_RS16045	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
G5B40_RS16045	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
G5B40_RS16050	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
G5B40_RS16055	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
G5B40_RS16065	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
G5B40_RS16070	COG1185	polyribonucleotide nucleotidyltransferase activity
G5B40_RS16075	COG1028	Short-chain dehydrogenase reductase Sdr
G5B40_RS16080	COG0697	spore germination
G5B40_RS16105	COG2030	dehydratase
G5B40_RS16130	COG0039	L-malate dehydrogenase activity
G5B40_RS16135	COG0045	succinate-CoA ligase (ADP-forming) activity
G5B40_RS16145	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
G5B40_RS16150	COG0567	Dehydrogenase, E1 component
G5B40_RS16155	COG0508	dehydrogenase complex catalyzes the overall conversion of
G5B40_RS16180	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
G5B40_RS16195	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
G5B40_RS16205	COG2835	tetraacyldisaccharide 4'-kinase activity
G5B40_RS16235	COG1216	Glycosyl transferase, family 2
G5B40_RS16235	COG0463	Glycosyl transferase, family 2
G5B40_RS16255	COG1494	fructose-1,6-bisphosphatase
G5B40_RS16265	COG0436	Aminotransferase
G5B40_RS16280	COG3243	poly(R)-hydroxyalkanoic acid synthase
G5B40_RS16295	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G5B40_RS16300	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G5B40_RS16305	COG1121	(ABC) transporter
G5B40_RS16330	COG0473	3-isopropylmalate dehydrogenase activity
G5B40_RS16345	COG3483	tryptophan 2,3-dioxygenase activity
G5B40_RS16350	COG0583	DNA-binding transcription factor activity
G5B40_RS16355	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
G5B40_RS16395	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
G5B40_RS16400	COG1573	uracil-dna glycosylase
G5B40_RS16405	COG0521	Mo-molybdopterin cofactor biosynthetic process
G5B40_RS16420	COG0494	nUDIX hydrolase
G5B40_RS16425	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
G5B40_RS16430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G5B40_RS16500	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
G5B40_RS16505	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G5B40_RS16520	COG1522	sequence-specific DNA binding
G5B40_RS16535	COG1012	belongs to the aldehyde dehydrogenase family
G5B40_RS16545	COG1280	lysine exporter protein (LysE YggA)
G5B40_RS16550	COG0456	acetyltransferase
G5B40_RS16595	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G5B40_RS16605	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G5B40_RS16645	COG0612	Peptidase, M16
G5B40_RS16650	COG0612	Peptidase, M16
G5B40_RS16660	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
G5B40_RS16665	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
G5B40_RS16675	COG2076	Multidrug Resistance protein
G5B40_RS16680	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
G5B40_RS16690	COG0131	Imidazoleglycerol-phosphate dehydratase
G5B40_RS16695	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
G5B40_RS16700	COG0534	Mate efflux family protein
G5B40_RS16725	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G5B40_RS16755	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
G5B40_RS16760	COG0250	Participates in transcription elongation, termination and antitermination
G5B40_RS16765	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
G5B40_RS16770	COG0081	regulation of translation
G5B40_RS16775	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
G5B40_RS16780	COG0222	ribosome binding
G5B40_RS16785	COG0085	RNA polymerase activity
G5B40_RS16790	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
G5B40_RS16795	COG3383	formate dehydrogenase (NAD+) activity
G5B40_RS16805	COG0564	pseudouridine synthase activity
G5B40_RS16815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G5B40_RS16820	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G5B40_RS16825	COG2154	pterin-4-alpha-carbinolamine dehydratase
G5B40_RS16850	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
G5B40_RS16860	COG0564	pseudouridine synthase activity
G5B40_RS16870	COG4206	TonB-dependent receptor
G5B40_RS16875	COG0504	CTP synthase activity
G5B40_RS16880	COG2059	Chromate
G5B40_RS16910	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
G5B40_RS16920	COG4786	Flagellar basal body rod
G5B40_RS16925	COG4786	Flagellar basal body rod
G5B40_RS16935	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
G5B40_RS16970	COG5443	negative regulation of bacterial-type flagellum assembly
G5B40_RS16995	COG1558	bacterial-type flagellum-dependent cell motility
G5B40_RS17000	COG1677	Flagellar hook-basal body complex protein FliE
G5B40_RS17005	COG1987	bacterial-type flagellum assembly
G5B40_RS17015	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
G5B40_RS17025	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
G5B40_RS17040	COG0469	pyruvate kinase activity
G5B40_RS17060	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
G5B40_RS17070	COG0107	imidazoleglycerol-phosphate synthase activity
G5B40_RS17075	COG0140	phosphoribosyl-ATP diphosphatase activity
G5B40_RS17085	COG1086	Polysaccharide biosynthesis protein
G5B40_RS17090	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G5B40_RS17120	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
G5B40_RS17175	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G5B40_RS17190	COG1028	Short-chain dehydrogenase reductase Sdr
G5B40_RS17195	COG1802	Transcriptional regulator
G5B40_RS17205	COG0251	oxidation-reduction process
G5B40_RS17215	COG4771	TonB-dependent receptor
G5B40_RS17220	COG4178	(ABC) transporter
G5B40_RS17235	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
G5B40_RS17240	COG2860	membrane
G5B40_RS17245	COG0475	glutathione-regulated potassium exporter activity
G5B40_RS17245	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G5B40_RS17260	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
G5B40_RS17295	COG2084	Dehydrogenase
G5B40_RS17300	COG0129	dihydroxy-acid dehydratase activity
G5B40_RS17305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G5B40_RS17325	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G5B40_RS17340	COG0596	Alpha beta hydrolase
G5B40_RS17345	COG0435	Glutathione S-transferase
G5B40_RS17350	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
G5B40_RS17355	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G5B40_RS17380	COG4139	cobalamin transport
G5B40_RS17385	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
G5B40_RS17410	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G5B40_RS17425	COG1573	uracil-dna glycosylase
G5B40_RS17430	COG2267	carboxylic ester hydrolase activity
G5B40_RS17440	COG1278	Cold shock
G5B40_RS17450	COG3186	Phenylalanine-4-hydroxylase
G5B40_RS17455	COG1522	sequence-specific DNA binding
G5B40_RS17470	COG0356	it plays a direct role in the translocation of protons across the membrane
G5B40_RS17480	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
G5B40_RS17485	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
G5B40_RS17500	COG0138	bifunctional purine biosynthesis protein purh
G5B40_RS17515	COG0501	Belongs to the peptidase M48B family
G5B40_RS17520	COG5508	conserved small protein
G5B40_RS17535	COG3750	Belongs to the UPF0335 family
G5B40_RS17560	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
G5B40_RS17565	COG0218	Necessary for normal cell division and for the maintenance of normal septation
G5B40_RS17575	COG0706	membrane insertase activity
G5B40_RS17585	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
G5B40_RS17590	COG0242	peptide deformylase activity
G5B40_RS17600	COG1012	belongs to the aldehyde dehydrogenase family
G5B40_RS17615	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
G5B40_RS17630	COG2873	o-acetylhomoserine
G5B40_RS17635	COG1832	CoA-binding protein
G5B40_RS17640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G5B40_RS17655	COG0668	transmembrane transport
G5B40_RS17695	COG0625	glutathione transferase activity
G5B40_RS17700	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G5B40_RS17710	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G5B40_RS17725	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
G5B40_RS17730	COG0285	dihydrofolate synthase activity
G5B40_RS17740	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
G5B40_RS17750	COG1999	signal sequence binding
G5B40_RS17760	COG2205	protein histidine kinase activity
G5B40_RS17770	COG3178	'Phosphotransferase
G5B40_RS17775	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
G5B40_RS17780	COG2887	Belongs to the helicase family. UvrD subfamily
G5B40_RS17785	COG1074	ATP-dependent DNA helicase activity
G5B40_RS17795	COG1126	abc transporter atp-binding protein
G5B40_RS17810	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
G5B40_RS17815	COG0288	reversible hydration of carbon dioxide
G5B40_RS17835	COG0010	Belongs to the arginase family
G5B40_RS17845	COG4974	Belongs to the 'phage' integrase family
G5B40_RS17855	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
G5B40_RS17875	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
G5B40_RS17880	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
G5B40_RS17885	COG0355	proton-transporting ATP synthase activity, rotational mechanism
G5B40_RS17915	COG0741	lytic transglycosylase activity
G5B40_RS17920	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G5B40_RS17925	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
G5B40_RS17945	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G5B40_RS17950	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
G5B40_RS17960	COG0314	molybdopterin synthase activity
G5B40_RS17965	COG2205	protein histidine kinase activity
G5B40_RS17965	COG0784	Response regulator, receiver
G5B40_RS18000	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
G5B40_RS18005	COG1420	regulation of RNA biosynthetic process
G5B40_RS18020	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
G5B40_RS18025	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
G5B40_RS18055	COG0142	geranyltranstransferase activity
G5B40_RS18060	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
G5B40_RS18075	COG0406	alpha-ribazole phosphatase activity
G5B40_RS18095	COG0668	transmembrane transport
G5B40_RS18100	COG2267	carboxylic ester hydrolase activity
G5B40_RS18105	COG0730	response to heat
G5B40_RS18130	COG0626	cystathionine gamma-synthase activity
G5B40_RS18145	COG1024	Enoyl-CoA hydratase
G5B40_RS18150	COG1960	acyl-CoA dehydrogenase activity
G5B40_RS18170	COG0625	glutathione transferase activity
G5B40_RS18175	COG0028	Belongs to the TPP enzyme family
G5B40_RS18180	COG0280	phosphate acetyltransferase
G5B40_RS18180	COG0857	belongs to the CobB CobQ family
G5B40_RS18185	COG0372	Belongs to the citrate synthase family
G5B40_RS18195	COG0243	molybdopterin cofactor binding
G5B40_RS18200	COG0437	4 iron, 4 sulfur cluster binding
G5B40_RS18210	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G5B40_RS18215	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
G5B40_RS18220	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G5B40_RS18235	COG2204	response regulator
G5B40_RS18260	COG0612	Peptidase, M16
G5B40_RS18270	COG1678	Uncharacterized ACR, COG1678
G5B40_RS18345	COG4964	Belongs to the GSP D family
G5B40_RS18360	COG1196	nuclear chromosome segregation
G5B40_RS18360	COG0739	heme binding
G5B40_RS18360	COG0741	lytic transglycosylase activity
G5B40_RS18365	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G5B40_RS18380	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
G5B40_RS18390	COG1573	uracil-dna glycosylase
G5B40_RS18395	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
G5B40_RS18415	COG0471	metal ion transport
G5B40_RS18415	COG0490	domain, Protein
G5B40_RS18420	COG0220	tRNA (guanine-N7-)-methyltransferase activity
G5B40_RS18425	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
G5B40_RS18430	COG1396	sequence-specific DNA binding
G5B40_RS18435	COG0815	Transfers the fatty acyl group on membrane lipoproteins
G5B40_RS18440	COG1253	flavin adenine dinucleotide binding
G5B40_RS18445	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
G5B40_RS18450	COG1702	phosphate starvation-inducible protein PhoH
G5B40_RS18455	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
G5B40_RS18460	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
G5B40_RS18465	COG0539	negative regulation of cytoplasmic translation
G5B40_RS18470	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G5B40_RS18475	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G5B40_RS18480	COG1802	Transcriptional regulator
G5B40_RS18485	COG1024	Enoyl-CoA hydratase
G5B40_RS18495	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G5B40_RS18505	COG2188	Transcriptional regulator
G5B40_RS18510	COG0427	acetyl-CoA hydrolase
G5B40_RS18550	COG1028	Short-chain dehydrogenase reductase Sdr
G5B40_RS18555	COG1335	isochorismatase
G5B40_RS18570	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G5B40_RS18575	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
G5B40_RS18585	COG1802	Transcriptional regulator
G5B40_RS18610	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
G5B40_RS18620	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
G5B40_RS18625	COG5328	Belongs to the UPF0262 family
G5B40_RS18635	COG1473	amidohydrolase
G5B40_RS18640	COG0747	negative chemotaxis
G5B40_RS18650	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G5B40_RS18665	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
G5B40_RS18670	COG0424	maF-like protein
G5B40_RS18675	COG1530	ribonuclease E activity
G5B40_RS18680	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
G5B40_RS18690	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
G5B40_RS18705	COG0668	transmembrane transport
G5B40_RS18720	COG0527	aspartate kinase activity
G5B40_RS18725	COG1917	Cupin 2, conserved barrel domain protein
G5B40_RS18730	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
G5B40_RS18745	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G5B40_RS18760	COG1272	protein, Hemolysin III
G5B40_RS18765	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
G5B40_RS18770	COG0300	oxidoreductase activity
G5B40_RS18785	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
G5B40_RS18790	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G5B40_RS18800	COG0318	PFAM AMP-dependent synthetase and ligase
G5B40_RS18805	COG3119	arylsulfatase activity
G5B40_RS18825	COG0625	glutathione transferase activity
G5B40_RS18830	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
G5B40_RS18850	COG1960	acyl-CoA dehydrogenase activity
G5B40_RS18855	COG0028	Belongs to the TPP enzyme family
G5B40_RS18865	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G5B40_RS18875	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G5B40_RS18885	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
G5B40_RS18895	COG0124	histidyl-tRNA synthetase
G5B40_RS18900	COG3119	arylsulfatase activity
G5B40_RS18950	COG5507	3-demethylubiquinone-9 3-methyltransferase
G5B40_RS18970	COG0179	Fumarylacetoacetate (FAA) hydrolase
G5B40_RS18975	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
G5B40_RS18990	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
G5B40_RS19020	COG0625	glutathione transferase activity
G5B40_RS19025	COG1309	transcriptional regulator
G5B40_RS19030	COG1960	acyl-CoA dehydrogenase activity
G5B40_RS19040	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G5B40_RS19050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G5B40_RS19055	COG4770	biotin carboxylase activity
G5B40_RS19100	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G5B40_RS19110	COG0604	alcohol dehydrogenase
G5B40_RS19120	COG2937	Belongs to the GPAT DAPAT family
G5B40_RS19135	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G5B40_RS19135	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G5B40_RS19140	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G5B40_RS19145	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
G5B40_RS19150	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G5B40_RS19160	COG2814	Major facilitator Superfamily
G5B40_RS19170	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
G5B40_RS19175	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
G5B40_RS19195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G5B40_RS19205	COG0174	glutamine synthetase
G5B40_RS19210	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
G5B40_RS19220	COG0069	glutamate synthase activity
G5B40_RS19230	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G5B40_RS19260	COG4176	ABC-type proline glycine betaine transport system permease component
G5B40_RS19265	COG0404	The glycine cleavage system catalyzes the degradation of glycine
G5B40_RS19270	COG0583	DNA-binding transcription factor activity
G5B40_RS19275	COG4638	Rieske (2fe-2S)
G5B40_RS19285	COG0156	8-amino-7-oxononanoate synthase activity
G5B40_RS19330	COG1028	Short-chain dehydrogenase reductase Sdr
G5B40_RS19335	COG1063	alcohol dehydrogenase
G5B40_RS19345	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G5B40_RS19350	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G5B40_RS19355	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G5B40_RS19365	COG1028	Short-chain dehydrogenase reductase Sdr
G5B40_RS19380	COG1309	transcriptional regulator
G5B40_RS19390	COG1032	radical SAM domain protein
G5B40_RS19420	COG0493	'glutamate synthase
G5B40_RS19435	COG0316	Belongs to the HesB IscA family
G5B40_RS19440	COG0232	Belongs to the dGTPase family. Type 2 subfamily
G5B40_RS19445	COG0018	arginyl-trna synthetase
G5B40_RS19460	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
G5B40_RS19465	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
G5B40_RS19470	COG0583	DNA-binding transcription factor activity
G5B40_RS19485	COG0436	Aminotransferase
G5B40_RS19505	COG3842	ATPase activity
G5B40_RS19520	COG3833	ABC-type maltose transport systems, permease component
G5B40_RS19570	COG1760	l-serine dehydratase
G5B40_RS19590	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
G5B40_RS19595	COG1960	acyl-CoA dehydrogenase activity
G5B40_RS19610	COG1024	Enoyl-CoA hydratase
G5B40_RS19615	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G5B40_RS19620	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
G5B40_RS19630	COG0793	Belongs to the peptidase S41A family
G5B40_RS19635	COG0494	nUDIX hydrolase
G5B40_RS19640	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
G5B40_RS19645	COG1028	Short-chain dehydrogenase reductase Sdr
G5B40_RS19680	COG1028	Short-chain dehydrogenase reductase Sdr
G5B40_RS19685	COG1846	Transcriptional regulator
G5B40_RS19690	COG1250	3-hydroxyacyl-CoA dehydrogenase
G5B40_RS19690	COG1024	Enoyl-CoA hydratase
G5B40_RS19695	COG1960	acyl-CoA dehydrogenase activity
G5B40_RS19755	COG0828	Belongs to the bacterial ribosomal protein bS21 family
G5B40_RS19765	COG1024	Enoyl-CoA hydratase
G5B40_RS19800	COG0300	oxidoreductase activity
G5B40_RS19810	COG1960	acyl-CoA dehydrogenase activity
G5B40_RS19815	COG2814	Major facilitator Superfamily
G5B40_RS19820	COG0009	L-threonylcarbamoyladenylate synthase
G5B40_RS19835	COG1381	Involved in DNA repair and RecF pathway recombination
G5B40_RS19855	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
G5B40_RS19865	COG0681	Belongs to the peptidase S26 family
G5B40_RS19870	COG0736	holo-[acyl-carrier-protein] synthase activity
G5B40_RS19880	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
G5B40_RS19890	COG0552	protein localization to endoplasmic reticulum
G5B40_RS19920	COG0501	Belongs to the peptidase M48B family
G5B40_RS19930	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G5B40_RS19940	COG0601	transmembrane transport
G5B40_RS19945	COG0747	negative chemotaxis
G5B40_RS19970	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
G5B40_RS19985	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
G5B40_RS19990	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
G5B40_RS20000	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G5B40_RS20020	COG2423	ornithine cyclodeaminase activity
G5B40_RS20030	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
G5B40_RS20040	COG0277	FAD linked oxidase domain protein
G5B40_RS20045	COG0277	FAD linked oxidase domain protein
G5B40_RS20055	COG0247	lactate metabolic process
G5B40_RS20090	COG0559	Belongs to the binding-protein-dependent transport system permease family
G5B40_RS20125	COG0257	Belongs to the bacterial ribosomal protein bL36 family
G5B40_RS20140	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G5B40_RS20165	COG0284	orotidine-5'-phosphate decarboxylase activity
G5B40_RS20170	COG0542	response to heat
G5B40_RS20190	COG0174	glutamine synthetase
G5B40_RS20210	COG1960	acyl-CoA dehydrogenase activity
G5B40_RS20225	COG0049	tRNA binding
G5B40_RS20230	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
G5B40_RS20235	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G5B40_RS20240	COG0051	transcription antitermination factor activity, RNA binding
G5B40_RS20245	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
G5B40_RS20250	COG0088	Forms part of the polypeptide exit tunnel
G5B40_RS20255	COG0089	rRNA binding
G5B40_RS20260	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
G5B40_RS20265	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
G5B40_RS20270	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
G5B40_RS20275	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
G5B40_RS20325	COG0255	Belongs to the universal ribosomal protein uL29 family
G5B40_RS20330	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
G5B40_RS20335	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
G5B40_RS20340	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
G5B40_RS20345	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
G5B40_RS20350	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
G5B40_RS20355	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
G5B40_RS20360	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
G5B40_RS20365	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
G5B40_RS20370	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
G5B40_RS20375	COG1841	ribosomal large subunit assembly
G5B40_RS20380	COG0200	Binds to the 23S rRNA
G5B40_RS20390	COG0563	adenylate kinase activity
G5B40_RS20400	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
G5B40_RS20405	COG0202	RNA polymerase activity
G5B40_RS20410	COG0203	ribosomal protein L17
G5B40_RS20425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G5B40_RS20430	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
G5B40_RS20435	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
G5B40_RS20460	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G5B40_RS20460	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G5B40_RS20465	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
G5B40_RS20485	COG1115	amino acid carrier protein
G5B40_RS20495	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
G5B40_RS20500	COG2847	Copper chaperone PCu(A)C
G5B40_RS20510	COG0227	Belongs to the bacterial ribosomal protein bL28 family
G5B40_RS20520	COG1703	isobutyryl-CoA mutase activity
G5B40_RS20530	COG1643	Atp-dependent helicase
G5B40_RS20550	COG0281	malic enzyme
G5B40_RS20550	COG0280	phosphate acetyltransferase
G5B40_RS20560	COG0019	diaminopimelate decarboxylase activity
G5B40_RS20570	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
G5B40_RS20575	COG2832	Protein of unknown function (DUF454)
G5B40_RS20595	COG3409	Peptidoglycan-binding domain 1 protein
G5B40_RS20595	COG3267	Type II secretory pathway component ExeA
G5B40_RS20625	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
G5B40_RS20630	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
G5B40_RS20635	COG2001	Belongs to the MraZ family
G5B40_RS20640	COG0275	rRNA processing
G5B40_RS20655	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G5B40_RS20660	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
G5B40_RS20665	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G5B40_RS20670	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
G5B40_RS20680	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
G5B40_RS20685	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G5B40_RS20690	COG0812	UDP-N-acetylmuramate dehydrogenase activity
G5B40_RS20695	COG1181	Belongs to the D-alanine--D-alanine ligase family
G5B40_RS20700	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
G5B40_RS20705	COG0849	cell division
G5B40_RS20715	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G5B40_RS20720	COG0497	DNA recombination
G5B40_RS20730	COG0277	FAD linked oxidase domain protein
G5B40_RS20740	COG0038	chloride channel
G5B40_RS20745	COG0006	proline dipeptidase activity
G5B40_RS20755	COG1278	Cold shock
G5B40_RS20785	COG0659	secondary active sulfate transmembrane transporter activity
G5B40_RS20795	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
G5B40_RS20800	COG3830	Belongs to the UPF0237 family
G5B40_RS20800	COG0560	Phosphoserine phosphatase
G5B40_RS20845	COG0745	RESPONSE REGULATOR receiver
G5B40_RS20855	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity