locus-tag	class	description
JQ505_RS00105	COG0582	viral genome integration into host DNA
JQ505_RS00115	COG0470	DNA polymerase III
JQ505_RS00130	COG1754	DNA topoisomerase type I activity
JQ505_RS00130	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JQ505_RS00140	COG1278	Cold shock
JQ505_RS00145	COG1111	helicase
JQ505_RS00145	COG1205	dead DEAH box helicase
JQ505_RS00195	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JQ505_RS00200	COG0477	Major facilitator Superfamily
JQ505_RS00205	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JQ505_RS00215	COG2267	carboxylic ester hydrolase activity
JQ505_RS00250	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JQ505_RS00290	COG1408	metallophosphoesterase
JQ505_RS00315	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JQ505_RS00390	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS00395	COG0318	PFAM AMP-dependent synthetase and ligase
JQ505_RS00400	COG0477	Major facilitator Superfamily
JQ505_RS00405	COG0384	phenazine biosynthesis protein PhzF
JQ505_RS00425	COG0310	cobalt ion transport
JQ505_RS00440	COG1122	ATPase activity
JQ505_RS00455	COG0298	carbon dioxide binding
JQ505_RS00475	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
JQ505_RS00510	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
JQ505_RS00520	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
JQ505_RS00525	COG0375	protein maturation
JQ505_RS00530	COG0640	Transcriptional regulator
JQ505_RS00535	COG1877	trehalose-phosphatase activity
JQ505_RS00535	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JQ505_RS00615	COG1028	Short-chain dehydrogenase reductase Sdr
JQ505_RS00640	COG3273	potassium ion transport
JQ505_RS00640	COG0471	metal ion transport
JQ505_RS00680	COG1028	Short-chain dehydrogenase reductase Sdr
JQ505_RS00725	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JQ505_RS00735	COG1024	Enoyl-CoA hydratase
JQ505_RS00750	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JQ505_RS00805	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JQ505_RS00815	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JQ505_RS00830	COG1024	Enoyl-CoA hydratase
JQ505_RS00840	COG1309	transcriptional regulator
JQ505_RS00860	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS00880	COG1309	transcriptional regulator
JQ505_RS00885	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JQ505_RS00890	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JQ505_RS00895	COG0860	N-Acetylmuramoyl-L-alanine amidase
JQ505_RS00910	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JQ505_RS00920	COG1250	3-hydroxyacyl-CoA dehydrogenase
JQ505_RS00920	COG1024	Enoyl-CoA hydratase
JQ505_RS00925	COG0183	Belongs to the thiolase family
JQ505_RS00930	COG2197	response regulator
JQ505_RS00945	COG3069	C4-dicarboxylate transmembrane transporter activity
JQ505_RS00980	COG1012	belongs to the aldehyde dehydrogenase family
JQ505_RS00985	COG2146	nitrite reductase [NAD(P)H] activity
JQ505_RS00990	COG0405	Gamma-glutamyltransferase
JQ505_RS01050	COG2197	response regulator
JQ505_RS01065	COG1028	Short-chain dehydrogenase reductase Sdr
JQ505_RS01120	COG0477	Major facilitator Superfamily
JQ505_RS01150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JQ505_RS01210	COG3226	Transcriptional regulator
JQ505_RS01215	COG1028	Short-chain dehydrogenase reductase Sdr
JQ505_RS01225	COG0583	DNA-binding transcription factor activity
JQ505_RS01230	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JQ505_RS01240	COG5473	translation initiation factor activity
JQ505_RS01250	COG0343	queuine tRNA-ribosyltransferase activity
JQ505_RS01255	COG2814	Major facilitator Superfamily
JQ505_RS01275	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JQ505_RS01300	COG2072	flavoprotein involved in K transport
JQ505_RS01315	COG1472	Belongs to the glycosyl hydrolase 3 family
JQ505_RS01335	COG2409	Drug exporters of the RND superfamily
JQ505_RS01370	COG0590	tRNA wobble adenosine to inosine editing
JQ505_RS01380	COG0287	Prephenate dehydrogenase
JQ505_RS01385	COG0154	amidase activity
JQ505_RS01425	COG0270	DNA (cytosine-5-)-methyltransferase activity
JQ505_RS01435	COG0730	response to heat
JQ505_RS01440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JQ505_RS01440	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JQ505_RS01460	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JQ505_RS01470	COG5479	isomerase activity
JQ505_RS01470	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
JQ505_RS01490	COG1063	alcohol dehydrogenase
JQ505_RS01515	COG1216	Glycosyl transferase, family 2
JQ505_RS01530	COG1216	Glycosyl transferase, family 2
JQ505_RS01540	COG1215	transferase activity, transferring glycosyl groups
JQ505_RS01545	COG0463	Glycosyl transferase, family 2
JQ505_RS01555	COG1088	dTDP-glucose 4,6-dehydratase activity
JQ505_RS01560	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
JQ505_RS01565	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
JQ505_RS01580	COG0277	FAD linked oxidase domain protein
JQ505_RS01585	COG1028	Short-chain dehydrogenase reductase Sdr
JQ505_RS01600	COG0247	lactate metabolic process
JQ505_RS01600	COG0277	FAD linked oxidase domain protein
JQ505_RS01635	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JQ505_RS01640	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JQ505_RS01640	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
JQ505_RS01640	COG3321	synthase
JQ505_RS01645	COG0318	PFAM AMP-dependent synthetase and ligase
JQ505_RS01655	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
JQ505_RS01665	COG5479	isomerase activity
JQ505_RS01665	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
JQ505_RS01675	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JQ505_RS01680	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
JQ505_RS01685	COG0671	phosphoesterase, PA-phosphatase related
JQ505_RS01690	COG1216	Glycosyl transferase, family 2
JQ505_RS01700	COG0789	Transcriptional regulator
JQ505_RS01710	COG0438	transferase activity, transferring glycosyl groups
JQ505_RS01725	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JQ505_RS01730	COG1733	regulation of RNA biosynthetic process
JQ505_RS01765	COG2385	sporulation resulting in formation of a cellular spore
JQ505_RS01775	COG0561	phosphatase activity
JQ505_RS01780	COG0204	Acyl-transferase
JQ505_RS01785	COG2146	nitrite reductase [NAD(P)H] activity
JQ505_RS01785	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JQ505_RS01810	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JQ505_RS01840	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JQ505_RS01865	COG0477	Major facilitator Superfamily
JQ505_RS01875	COG0789	Transcriptional regulator
JQ505_RS01880	COG0659	secondary active sulfate transmembrane transporter activity
JQ505_RS01895	COG1309	transcriptional regulator
JQ505_RS01905	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JQ505_RS01945	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JQ505_RS01950	COG1937	Protein conserved in bacteria
JQ505_RS01955	COG2226	methyltransferase
JQ505_RS01980	COG0121	glutamine amidotransferase
JQ505_RS01985	COG0477	Major facilitator Superfamily
JQ505_RS01990	COG1597	lipid kinase activity
JQ505_RS02015	COG0121	glutamine amidotransferase
JQ505_RS02025	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JQ505_RS02090	COG1024	Enoyl-CoA hydratase
JQ505_RS02130	COG1028	Short-chain dehydrogenase reductase Sdr
JQ505_RS02150	COG0183	Belongs to the thiolase family
JQ505_RS02160	COG0604	alcohol dehydrogenase
JQ505_RS02160	COG3321	synthase
JQ505_RS02160	COG1028	Short-chain dehydrogenase reductase Sdr
JQ505_RS02165	COG1024	Enoyl-CoA hydratase
JQ505_RS02225	COG0628	permease
JQ505_RS02230	COG2197	response regulator
JQ505_RS02240	COG1316	TRANSCRIPTIONal
JQ505_RS02275	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JQ505_RS02285	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JQ505_RS02295	COG2119	membrane
JQ505_RS02305	COG2814	Major facilitator Superfamily
JQ505_RS02315	COG2508	Transcriptional regulator
JQ505_RS02380	COG1573	uracil-dna glycosylase
JQ505_RS02385	COG4770	biotin carboxylase activity
JQ505_RS02415	COG2072	flavoprotein involved in K transport
JQ505_RS02430	COG3706	GGDEF domain
JQ505_RS02435	COG1012	belongs to the aldehyde dehydrogenase family
JQ505_RS02440	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JQ505_RS02445	COG2161	toxin-antitoxin pair type II binding
JQ505_RS02485	COG2072	flavoprotein involved in K transport
JQ505_RS02495	COG1396	sequence-specific DNA binding
JQ505_RS02505	COG1309	transcriptional regulator
JQ505_RS02515	COG0183	Belongs to the thiolase family
JQ505_RS02520	COG0318	PFAM AMP-dependent synthetase and ligase
JQ505_RS02525	COG1024	Enoyl-CoA hydratase
JQ505_RS02530	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS02540	COG1012	belongs to the aldehyde dehydrogenase family
JQ505_RS02540	COG2030	dehydratase
JQ505_RS02545	COG0183	Belongs to the thiolase family
JQ505_RS02555	COG1012	belongs to the aldehyde dehydrogenase family
JQ505_RS02560	COG0477	Major facilitator Superfamily
JQ505_RS02570	COG1414	Transcriptional regulator
JQ505_RS02575	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JQ505_RS02585	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JQ505_RS02605	COG0305	Participates in initiation and elongation during chromosome replication
JQ505_RS02650	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JQ505_RS02665	COG2501	S4 domain
JQ505_RS02670	COG0415	Belongs to the DNA photolyase family
JQ505_RS02680	COG0702	epimerase
JQ505_RS02720	COG2409	Drug exporters of the RND superfamily
JQ505_RS02765	COG0318	PFAM AMP-dependent synthetase and ligase
JQ505_RS02775	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JQ505_RS02795	COG1012	belongs to the aldehyde dehydrogenase family
JQ505_RS02820	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JQ505_RS02835	COG1609	Transcriptional regulator
JQ505_RS02850	COG1012	belongs to the aldehyde dehydrogenase family
JQ505_RS02855	COG1063	alcohol dehydrogenase
JQ505_RS02860	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JQ505_RS02865	COG1609	Transcriptional regulator
JQ505_RS02885	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
JQ505_RS02895	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
JQ505_RS02910	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JQ505_RS02910	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JQ505_RS02930	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
JQ505_RS02945	COG0789	Transcriptional regulator
JQ505_RS02955	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
JQ505_RS02970	COG0070	glutamate synthase
JQ505_RS02970	COG0069	glutamate synthase activity
JQ505_RS02970	COG0067	glutamate synthase
JQ505_RS02980	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JQ505_RS03005	COG1716	ATPase activity
JQ505_RS03010	COG1716	ATPase activity
JQ505_RS03025	COG0768	penicillin binding
JQ505_RS03030	COG0515	serine threonine protein kinase
JQ505_RS03035	COG0515	serine threonine protein kinase
JQ505_RS03035	COG2815	serine threonine protein kinase
JQ505_RS03060	COG0457	Tetratricopeptide repeat
JQ505_RS03060	COG0705	Rhomboid family
JQ505_RS03105	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JQ505_RS03110	COG2837	iron assimilation
JQ505_RS03135	COG1309	transcriptional regulator
JQ505_RS03140	COG0693	protein deglycase activity
JQ505_RS03165	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JQ505_RS03190	COG2018	Roadblock/LC7 domain
JQ505_RS03200	COG0187	DNA topoisomerase II activity
JQ505_RS03220	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
JQ505_RS03230	COG0592	DNA-directed DNA polymerase activity
JQ505_RS03235	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JQ505_RS03240	COG0230	Belongs to the bacterial ribosomal protein bL34 family
JQ505_RS03250	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JQ505_RS03255	COG0706	membrane insertase activity
JQ505_RS03265	COG0357	Ribosomal RNA small subunit methyltransferase G
JQ505_RS03270	COG1192	Involved in chromosome partitioning
JQ505_RS03285	COG3409	Peptidoglycan-binding domain 1 protein
JQ505_RS03285	COG0860	N-Acetylmuramoyl-L-alanine amidase
JQ505_RS03290	COG0492	ferredoxin-NADP+ reductase activity
JQ505_RS03290	COG3118	belongs to the thioredoxin family
JQ505_RS03315	COG1309	transcriptional regulator
JQ505_RS03325	COG1595	DNA-templated transcription, initiation
JQ505_RS03345	COG0617	tRNA 3'-terminal CCA addition
JQ505_RS03355	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
JQ505_RS03360	COG0243	molybdopterin cofactor binding
JQ505_RS03410	COG1678	Uncharacterized ACR, COG1678
JQ505_RS03415	COG0076	glutamate decarboxylase activity
JQ505_RS03440	COG0495	leucyl-tRNA aminoacylation
JQ505_RS03445	COG2267	carboxylic ester hydrolase activity
JQ505_RS03455	COG1253	flavin adenine dinucleotide binding
JQ505_RS03460	COG3631	Ketosteroid isomerase-related protein
JQ505_RS03465	COG1253	flavin adenine dinucleotide binding
JQ505_RS03475	COG0300	oxidoreductase activity
JQ505_RS03485	COG1796	DNA polymerase
JQ505_RS03485	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JQ505_RS03515	COG0318	PFAM AMP-dependent synthetase and ligase
JQ505_RS03565	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JQ505_RS03575	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
JQ505_RS03580	COG0753	catalase activity
JQ505_RS03590	COG3350	monooxygenase activity
JQ505_RS03595	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JQ505_RS03620	COG1064	alcohol dehydrogenase
JQ505_RS03625	COG0459	protein refolding
JQ505_RS03635	COG2902	Dehydrogenase
JQ505_RS03640	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JQ505_RS03645	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS03650	COG1012	belongs to the aldehyde dehydrogenase family
JQ505_RS03665	COG2161	toxin-antitoxin pair type II binding
JQ505_RS03670	COG2026	Addiction module toxin, RelE StbE family
JQ505_RS03700	COG1113	amino acid transport
JQ505_RS03705	COG0318	PFAM AMP-dependent synthetase and ligase
JQ505_RS03720	COG3835	regulator
JQ505_RS03755	COG1126	abc transporter atp-binding protein
JQ505_RS03760	COG0765	amino acid transport
JQ505_RS03780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JQ505_RS03795	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS03800	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS03870	COG3842	ATPase activity
JQ505_RS03895	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JQ505_RS03935	COG1695	Transcriptional regulator
JQ505_RS03960	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JQ505_RS03995	COG0629	single-stranded DNA binding
JQ505_RS04000	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JQ505_RS04005	COG0359	binds to the 23S rRNA
JQ505_RS04015	COG2814	Major facilitator Superfamily
JQ505_RS04025	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JQ505_RS04045	COG0405	Gamma-glutamyltransferase
JQ505_RS04050	COG2855	membrane
JQ505_RS04055	COG2011	ABC-type metal ion transport system permease component
JQ505_RS04060	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JQ505_RS04065	COG1464	Belongs to the NlpA lipoprotein family
JQ505_RS04090	COG0745	RESPONSE REGULATOR receiver
JQ505_RS04125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JQ505_RS04135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JQ505_RS04145	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JQ505_RS04150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JQ505_RS04155	COG4172	Belongs to the ABC transporter superfamily
JQ505_RS04160	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JQ505_RS04170	COG0747	negative chemotaxis
JQ505_RS04175	COG0477	Major facilitator Superfamily
JQ505_RS04180	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JQ505_RS04185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JQ505_RS04195	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JQ505_RS04200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JQ505_RS04205	COG1126	abc transporter atp-binding protein
JQ505_RS04215	COG3842	ATPase activity
JQ505_RS04220	COG4208	sulfate ABC transporter
JQ505_RS04230	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
JQ505_RS04240	COG0069	glutamate synthase activity
JQ505_RS04260	COG0842	Transport permease protein
JQ505_RS04260	COG1716	ATPase activity
JQ505_RS04260	COG1131	(ABC) transporter
JQ505_RS04265	COG0318	PFAM AMP-dependent synthetase and ligase
JQ505_RS04270	COG0477	Major facilitator Superfamily
JQ505_RS04275	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JQ505_RS04290	COG1017	nitric oxide dioxygenase activity
JQ505_RS04290	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JQ505_RS04330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JQ505_RS04335	COG0431	NADPH-dependent FMN reductase
JQ505_RS04360	COG3387	PFAM Glycoside hydrolase 15-related
JQ505_RS04400	COG3835	regulator
JQ505_RS04415	COG2080	2 iron, 2 sulfur cluster binding
JQ505_RS04415	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JQ505_RS04440	COG1982	Orn Lys Arg decarboxylase major
JQ505_RS04490	COG4266	Belongs to the allantoicase family
JQ505_RS04495	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JQ505_RS04505	COG1940	carbohydrate kinase activity
JQ505_RS04510	COG0477	Major facilitator Superfamily
JQ505_RS04515	COG1940	carbohydrate kinase activity
JQ505_RS04520	COG2186	Transcriptional regulator
JQ505_RS04525	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JQ505_RS04530	COG1116	anion transmembrane transporter activity
JQ505_RS04535	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JQ505_RS04550	COG0800	Aldolase
JQ505_RS04560	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JQ505_RS04565	COG1846	Transcriptional regulator
JQ505_RS04565	COG1940	carbohydrate kinase activity
JQ505_RS04580	COG0477	Major facilitator Superfamily
JQ505_RS04585	COG1595	DNA-templated transcription, initiation
JQ505_RS04625	COG2890	protein-(glutamine-N5) methyltransferase activity
JQ505_RS04640	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JQ505_RS04645	COG2193	ferroxidase activity
JQ505_RS04670	COG1414	Transcriptional regulator
JQ505_RS04680	COG1028	Short-chain dehydrogenase reductase Sdr
JQ505_RS04685	COG0583	DNA-binding transcription factor activity
JQ505_RS04690	COG0477	Major facilitator Superfamily
JQ505_RS04695	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JQ505_RS04705	COG0656	L-ascorbic acid biosynthetic process
JQ505_RS04710	COG0673	inositol 2-dehydrogenase activity
JQ505_RS04730	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS04735	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JQ505_RS04740	COG2271	Major facilitator Superfamily
JQ505_RS04745	COG0183	Belongs to the thiolase family
JQ505_RS04760	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS04770	COG0183	Belongs to the thiolase family
JQ505_RS04780	COG0583	DNA-binding transcription factor activity
JQ505_RS04785	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JQ505_RS04810	COG1358	cellular component organization or biogenesis
JQ505_RS04865	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
JQ505_RS04870	COG1609	Transcriptional regulator
JQ505_RS04875	COG0667	Aldo Keto reductase
JQ505_RS04880	COG0789	Transcriptional regulator
JQ505_RS04895	COG2318	DinB family
JQ505_RS04905	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JQ505_RS04925	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS04940	COG0318	PFAM AMP-dependent synthetase and ligase
JQ505_RS04945	COG0183	Belongs to the thiolase family
JQ505_RS04950	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JQ505_RS04955	COG1309	transcriptional regulator
JQ505_RS04985	COG0183	Belongs to the thiolase family
JQ505_RS04990	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS04995	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS05000	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS05015	COG0318	PFAM AMP-dependent synthetase and ligase
JQ505_RS05055	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
JQ505_RS05070	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
JQ505_RS05110	COG1024	Enoyl-CoA hydratase
JQ505_RS05120	COG0183	Belongs to the thiolase family
JQ505_RS05140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JQ505_RS05160	COG2030	dehydratase
JQ505_RS05165	COG1012	belongs to the aldehyde dehydrogenase family
JQ505_RS05170	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JQ505_RS05185	COG1012	belongs to the aldehyde dehydrogenase family
JQ505_RS05190	COG0318	PFAM AMP-dependent synthetase and ligase
JQ505_RS05200	COG2124	cytochrome p450
JQ505_RS05205	COG1028	Short-chain dehydrogenase reductase Sdr
JQ505_RS05215	COG1053	succinate dehydrogenase
JQ505_RS05260	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
JQ505_RS05260	COG0674	pyruvate-flavodoxin oxidoreductase activity
JQ505_RS05265	COG1013	pyruvate-flavodoxin oxidoreductase activity
JQ505_RS05290	COG1028	Short-chain dehydrogenase reductase Sdr
JQ505_RS05300	COG1902	pentaerythritol trinitrate reductase activity
JQ505_RS05300	COG0446	pyridine nucleotide-disulphide oxidoreductase
JQ505_RS05305	COG2072	flavoprotein involved in K transport
JQ505_RS05320	COG2072	flavoprotein involved in K transport
JQ505_RS05325	COG1028	Short-chain dehydrogenase reductase Sdr
JQ505_RS05345	COG1024	Enoyl-CoA hydratase
JQ505_RS05350	COG2186	Transcriptional regulator
JQ505_RS05365	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JQ505_RS05390	COG2072	flavoprotein involved in K transport
JQ505_RS05395	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JQ505_RS05400	COG0166	Belongs to the GPI family
JQ505_RS05410	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
JQ505_RS05420	COG5650	phosphatidylinositol metabolic process
JQ505_RS05430	COG0346	lactoylglutathione lyase activity
JQ505_RS05440	COG0318	PFAM AMP-dependent synthetase and ligase
JQ505_RS05455	COG2175	clavaminate synthase activity
JQ505_RS05470	COG0596	Alpha beta hydrolase
JQ505_RS05500	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JQ505_RS05520	COG2814	Major facilitator Superfamily
JQ505_RS05540	COG4638	Rieske (2fe-2S)
JQ505_RS05570	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JQ505_RS05580	COG1414	Transcriptional regulator
JQ505_RS05585	COG3485	protocatechuate 3,4-dioxygenase
JQ505_RS05590	COG4948	Mandelate Racemase Muconate Lactonizing
JQ505_RS05595	COG4829	muconolactone delta-isomerase
JQ505_RS05605	COG0657	acetylesterase activity
JQ505_RS05610	COG3384	dioxygenase
JQ505_RS05615	COG2267	carboxylic ester hydrolase activity
JQ505_RS05620	COG0583	DNA-binding transcription factor activity
JQ505_RS05720	COG2271	Major facilitator Superfamily
JQ505_RS05725	COG0183	Belongs to the thiolase family
JQ505_RS05730	COG1414	Transcriptional regulator
JQ505_RS05735	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JQ505_RS05745	COG3485	protocatechuate 3,4-dioxygenase
JQ505_RS05750	COG3485	protocatechuate 3,4-dioxygenase
JQ505_RS05780	COG0628	permease
JQ505_RS05790	COG2188	Transcriptional regulator
JQ505_RS05800	COG1620	l-lactate permease
JQ505_RS05805	COG0247	lactate metabolic process
JQ505_RS05810	COG1139	Iron-sulfur cluster binding protein
JQ505_RS05815	COG1556	Lactate utilization protein
JQ505_RS05825	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JQ505_RS05835	COG1846	Transcriptional regulator
JQ505_RS05845	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JQ505_RS05900	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS05905	COG0183	Belongs to the thiolase family
JQ505_RS05910	COG1028	Short-chain dehydrogenase reductase Sdr
JQ505_RS05915	COG1028	Short-chain dehydrogenase reductase Sdr
JQ505_RS05920	COG1113	amino acid transport
JQ505_RS05925	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JQ505_RS05935	COG3185	4-Hydroxyphenylpyruvate dioxygenase
JQ505_RS05970	COG1309	transcriptional regulator
JQ505_RS05995	COG1063	alcohol dehydrogenase
JQ505_RS06000	COG1028	Short-chain dehydrogenase reductase Sdr
JQ505_RS06015	COG1028	Short-chain dehydrogenase reductase Sdr
JQ505_RS06030	COG2030	dehydratase
JQ505_RS06040	COG1028	Short-chain dehydrogenase reductase Sdr
JQ505_RS06055	COG0318	PFAM AMP-dependent synthetase and ligase
JQ505_RS06060	COG0183	Belongs to the thiolase family
JQ505_RS06110	COG2072	flavoprotein involved in K transport
JQ505_RS06120	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS06150	COG1024	Enoyl-CoA hydratase
JQ505_RS06155	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JQ505_RS06155	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JQ505_RS06190	COG2161	toxin-antitoxin pair type II binding
JQ505_RS06195	COG4115	mRNA cleavage
JQ505_RS06200	COG2267	carboxylic ester hydrolase activity
JQ505_RS06265	COG0318	PFAM AMP-dependent synthetase and ligase
JQ505_RS06290	COG3246	L-lysine catabolic process to acetate
JQ505_RS06295	COG2175	clavaminate synthase activity
JQ505_RS06305	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JQ505_RS06315	COG2855	membrane
JQ505_RS06335	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JQ505_RS06350	COG1250	3-hydroxyacyl-CoA dehydrogenase
JQ505_RS06355	COG1309	transcriptional regulator
JQ505_RS06375	COG2130	NADP-dependent
JQ505_RS06395	COG1028	Short-chain dehydrogenase reductase Sdr
JQ505_RS06415	COG0183	Belongs to the thiolase family
JQ505_RS06420	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS06430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JQ505_RS06440	COG1024	Enoyl-CoA hydratase
JQ505_RS06445	COG2814	Major facilitator Superfamily
JQ505_RS06455	COG1028	Short-chain dehydrogenase reductase Sdr
JQ505_RS06460	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JQ505_RS06475	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS06495	COG3842	ATPase activity
JQ505_RS06500	COG4208	sulfate ABC transporter
JQ505_RS06535	COG2267	carboxylic ester hydrolase activity
JQ505_RS06540	COG1024	Enoyl-CoA hydratase
JQ505_RS06545	COG0318	PFAM AMP-dependent synthetase and ligase
JQ505_RS06565	COG0328	RNA-DNA hybrid ribonuclease activity
JQ505_RS06570	COG0604	alcohol dehydrogenase
JQ505_RS06575	COG4607	ABC-type enterochelin transport system periplasmic component
JQ505_RS06580	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JQ505_RS06585	COG4605	iron ion homeostasis
JQ505_RS06590	COG4604	ABC transporter, ATP-binding protein
JQ505_RS06600	COG0640	Transcriptional regulator
JQ505_RS06610	COG0493	'glutamate synthase
JQ505_RS06610	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
JQ505_RS06615	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
JQ505_RS06615	COG0674	pyruvate-flavodoxin oxidoreductase activity
JQ505_RS06615	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
JQ505_RS06615	COG1013	pyruvate-flavodoxin oxidoreductase activity
JQ505_RS06620	COG0167	dihydroorotate dehydrogenase activity
JQ505_RS06625	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JQ505_RS06660	COG2072	flavoprotein involved in K transport
JQ505_RS06670	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JQ505_RS06675	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JQ505_RS06680	COG0798	PFAM Bile acid sodium symporter
JQ505_RS06685	COG0640	Transcriptional regulator
JQ505_RS06690	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JQ505_RS06705	COG2873	o-acetylhomoserine
JQ505_RS06715	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
JQ505_RS06730	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
JQ505_RS06750	COG0243	molybdopterin cofactor binding
JQ505_RS06760	COG0425	Belongs to the sulfur carrier protein TusA family
JQ505_RS06770	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JQ505_RS06770	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JQ505_RS06780	COG0129	dihydroxy-acid dehydratase activity
JQ505_RS06790	COG0667	Aldo Keto reductase
JQ505_RS06820	COG0318	PFAM AMP-dependent synthetase and ligase
JQ505_RS06825	COG2197	response regulator
JQ505_RS06835	COG5002	protein histidine kinase activity
JQ505_RS06840	COG0745	RESPONSE REGULATOR receiver
JQ505_RS06850	COG2132	Multicopper oxidase
JQ505_RS06860	COG2217	Heavy metal translocating P-type atpase
JQ505_RS06910	COG0598	Magnesium transport protein CorA
JQ505_RS06920	COG1793	dna ligase
JQ505_RS06935	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JQ505_RS06940	COG3360	Dodecin
JQ505_RS06950	COG1376	ErfK ybiS ycfS ynhG family protein
JQ505_RS06965	COG1653	transport
JQ505_RS06970	COG3842	ATPase activity
JQ505_RS06990	COG0438	transferase activity, transferring glycosyl groups
JQ505_RS07005	COG0154	amidase activity
JQ505_RS07015	COG4566	intracellular signal transduction
JQ505_RS07025	COG1028	Short-chain dehydrogenase reductase Sdr
JQ505_RS07035	COG4638	Rieske (2fe-2S)
JQ505_RS07055	COG3852	Histidine kinase
JQ505_RS07065	COG5002	protein histidine kinase activity
JQ505_RS07080	COG1028	Short-chain dehydrogenase reductase Sdr
JQ505_RS07090	COG0704	Plays a role in the regulation of phosphate uptake
JQ505_RS07095	COG0028	Belongs to the TPP enzyme family
JQ505_RS07125	COG2311	Membrane
JQ505_RS07135	COG3590	peptidase
JQ505_RS07145	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JQ505_RS07190	COG0351	phosphomethylpyrimidine kinase
JQ505_RS07195	COG2135	peptidase activity
JQ505_RS07235	COG1024	Enoyl-CoA hydratase
JQ505_RS07255	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS07275	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JQ505_RS07295	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JQ505_RS07305	COG1024	Enoyl-CoA hydratase
JQ505_RS07320	COG2301	Belongs to the HpcH HpaI aldolase family
JQ505_RS07330	COG2188	Transcriptional regulator
JQ505_RS07345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JQ505_RS07365	COG2267	carboxylic ester hydrolase activity
JQ505_RS07435	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS07440	COG0657	acetylesterase activity
JQ505_RS07460	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JQ505_RS07465	COG0488	(ABC) transporter
JQ505_RS07470	COG0768	penicillin binding
JQ505_RS07485	COG3104	oligopeptide transport
JQ505_RS07495	COG2353	YceI-like domain
JQ505_RS07555	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JQ505_RS07575	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
JQ505_RS07605	COG1045	serine acetyltransferase
JQ505_RS07625	COG0412	Dienelactone hydrolase
JQ505_RS07640	COG0438	transferase activity, transferring glycosyl groups
JQ505_RS07665	COG4981	capsule polysaccharide biosynthetic process
JQ505_RS07680	COG0589	response to stress
JQ505_RS07685	COG1472	Belongs to the glycosyl hydrolase 3 family
JQ505_RS07690	COG1309	transcriptional regulator
JQ505_RS07710	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JQ505_RS07725	COG2030	dehydratase
JQ505_RS07730	COG1028	Short-chain dehydrogenase reductase Sdr
JQ505_RS07735	COG0183	Belongs to the thiolase family
JQ505_RS07745	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS07750	COG0500	methyltransferase
JQ505_RS07780	COG0446	pyridine nucleotide-disulphide oxidoreductase
JQ505_RS07845	COG1357	PFAM Pentapeptide repeats (8 copies)
JQ505_RS07915	COG1028	Short-chain dehydrogenase reductase Sdr
JQ505_RS07920	COG1028	Short-chain dehydrogenase reductase Sdr
JQ505_RS07945	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JQ505_RS07950	COG0022	dehydrogenase e1 component
JQ505_RS07955	COG0508	dehydrogenase complex catalyzes the overall conversion of
JQ505_RS07960	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JQ505_RS07965	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JQ505_RS07975	COG3284	Transcriptional regulator
JQ505_RS07995	COG0151	Belongs to the GarS family
JQ505_RS08005	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JQ505_RS08010	COG4948	Mandelate Racemase Muconate Lactonizing
JQ505_RS08025	COG4166	transmembrane transport
JQ505_RS08035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JQ505_RS08040	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JQ505_RS08070	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JQ505_RS08080	COG3971	2-oxopent-4-enoate hydratase activity
JQ505_RS08085	COG4569	acetaldehyde dehydrogenase (acetylating) activity
JQ505_RS08100	COG0346	lactoylglutathione lyase activity
JQ505_RS08180	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS08185	COG1309	transcriptional regulator
JQ505_RS08190	COG0183	Belongs to the thiolase family
JQ505_RS08195	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS08200	COG2030	dehydratase
JQ505_RS08215	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JQ505_RS08220	COG0318	PFAM AMP-dependent synthetase and ligase
JQ505_RS08230	COG0318	PFAM AMP-dependent synthetase and ligase
JQ505_RS08240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JQ505_RS08245	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS08255	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS08265	COG0183	Belongs to the thiolase family
JQ505_RS08300	COG0174	glutamine synthetase
JQ505_RS08305	COG2957	Belongs to the agmatine deiminase family
JQ505_RS08310	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JQ505_RS08330	COG1012	belongs to the aldehyde dehydrogenase family
JQ505_RS08360	COG1053	succinate dehydrogenase
JQ505_RS08365	COG2902	Dehydrogenase
JQ505_RS08375	COG0318	PFAM AMP-dependent synthetase and ligase
JQ505_RS08410	COG3231	kanamycin kinase activity
JQ505_RS08415	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS08455	COG2271	Major facilitator Superfamily
JQ505_RS08465	COG4948	Mandelate Racemase Muconate Lactonizing
JQ505_RS08485	COG1607	acyl-coa hydrolase
JQ505_RS08500	COG2015	COG2015, Alkyl sulfatase and related hydrolases
JQ505_RS08510	COG0318	PFAM AMP-dependent synthetase and ligase
JQ505_RS08515	COG1309	transcriptional regulator
JQ505_RS08520	COG1309	transcriptional regulator
JQ505_RS08525	COG2072	flavoprotein involved in K transport
JQ505_RS08535	COG0318	PFAM AMP-dependent synthetase and ligase
JQ505_RS08545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JQ505_RS08575	COG2814	Major facilitator Superfamily
JQ505_RS08580	COG0640	Transcriptional regulator
JQ505_RS08600	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JQ505_RS08610	COG2814	Major facilitator Superfamily
JQ505_RS08615	COG3246	L-lysine catabolic process to acetate
JQ505_RS08620	COG2175	clavaminate synthase activity
JQ505_RS08630	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS08640	COG0318	PFAM AMP-dependent synthetase and ligase
JQ505_RS08665	COG2855	membrane
JQ505_RS08695	COG1752	Esterase of the alpha-beta hydrolase superfamily
JQ505_RS08700	COG3467	pyridoxamine 5'-phosphate
JQ505_RS08705	COG2267	carboxylic ester hydrolase activity
JQ505_RS08715	COG0747	negative chemotaxis
JQ505_RS08730	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JQ505_RS08740	COG4608	Belongs to the ABC transporter superfamily
JQ505_RS08745	COG3387	PFAM Glycoside hydrolase 15-related
JQ505_RS08755	COG1028	Short-chain dehydrogenase reductase Sdr
JQ505_RS08780	COG2267	carboxylic ester hydrolase activity
JQ505_RS08785	COG3384	dioxygenase
JQ505_RS08795	COG2159	amidohydrolase
JQ505_RS08800	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JQ505_RS08805	COG1028	Short-chain dehydrogenase reductase Sdr
JQ505_RS08830	COG0633	Ferredoxin
JQ505_RS08845	COG2197	response regulator
JQ505_RS08880	COG0633	Ferredoxin
JQ505_RS08885	COG2197	response regulator
JQ505_RS08895	COG1024	Enoyl-CoA hydratase
JQ505_RS08900	COG0318	PFAM AMP-dependent synthetase and ligase
JQ505_RS08910	COG2030	dehydratase
JQ505_RS08915	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS08920	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JQ505_RS08925	COG2186	Transcriptional regulator
JQ505_RS08940	COG1028	Short-chain dehydrogenase reductase Sdr
JQ505_RS08945	COG0183	Belongs to the thiolase family
JQ505_RS08950	COG0427	acetyl-CoA hydrolase
JQ505_RS08955	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JQ505_RS08970	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JQ505_RS08975	COG1024	Enoyl-CoA hydratase
JQ505_RS08980	COG0697	spore germination
JQ505_RS08985	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JQ505_RS09020	COG2223	nitrite transmembrane transporter activity
JQ505_RS09025	COG2197	response regulator
JQ505_RS09035	COG0318	PFAM AMP-dependent synthetase and ligase
JQ505_RS09050	COG0633	Ferredoxin
JQ505_RS09060	COG1028	Short-chain dehydrogenase reductase Sdr
JQ505_RS09075	COG0604	alcohol dehydrogenase
JQ505_RS09090	COG1028	Short-chain dehydrogenase reductase Sdr
JQ505_RS09095	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS09100	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JQ505_RS09115	COG1309	transcriptional regulator
JQ505_RS09140	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JQ505_RS09155	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
JQ505_RS09175	COG0656	L-ascorbic acid biosynthetic process
JQ505_RS09240	COG4221	oxidoreductase activity
JQ505_RS09245	COG3848	Pyruvate phosphate dikinase
JQ505_RS09245	COG0574	Belongs to the PEP-utilizing enzyme family
JQ505_RS09260	COG1309	transcriptional regulator
JQ505_RS09265	COG1414	Transcriptional regulator
JQ505_RS09385	COG1064	alcohol dehydrogenase
JQ505_RS09395	COG1028	Short-chain dehydrogenase reductase Sdr
JQ505_RS09420	COG2267	carboxylic ester hydrolase activity
JQ505_RS09430	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JQ505_RS09435	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JQ505_RS09530	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JQ505_RS09535	COG1482	cell wall glycoprotein biosynthetic process
JQ505_RS09540	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JQ505_RS09545	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JQ505_RS09550	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JQ505_RS09555	COG2089	acid synthase
JQ505_RS09570	COG1083	cytidylyl-transferase
JQ505_RS09615	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
JQ505_RS09620	COG1088	dTDP-glucose 4,6-dehydratase activity
JQ505_RS09635	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JQ505_RS09640	COG0489	protein tyrosine kinase activity
JQ505_RS09645	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JQ505_RS09660	COG0784	Response regulator, receiver
JQ505_RS09665	COG4251	negative regulation of phosphorylation
JQ505_RS09670	COG0745	RESPONSE REGULATOR receiver
JQ505_RS09690	COG3239	Fatty acid desaturase
JQ505_RS09700	COG0247	lactate metabolic process
JQ505_RS09700	COG2181	nitrate reductase activity
JQ505_RS09730	COG0443	Heat shock 70 kDa protein
JQ505_RS09760	COG0443	Heat shock 70 kDa protein
JQ505_RS09765	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JQ505_RS09770	COG0484	heat shock protein binding
JQ505_RS09775	COG0789	Transcriptional regulator
JQ505_RS09780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JQ505_RS09785	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JQ505_RS09790	COG3631	Ketosteroid isomerase-related protein
JQ505_RS09795	COG1053	succinate dehydrogenase
JQ505_RS09845	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JQ505_RS09855	COG0318	PFAM AMP-dependent synthetase and ligase
JQ505_RS09935	COG0791	NLP P60 protein
JQ505_RS09945	COG1222	aaa ATPase
JQ505_RS09955	COG2197	response regulator
JQ505_RS09965	COG0542	response to heat
JQ505_RS10000	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JQ505_RS10035	COG0523	cobalamin synthesis protein
JQ505_RS10040	COG0586	Pfam SNARE associated Golgi protein
JQ505_RS10065	COG4129	membrane
JQ505_RS10085	COG4172	Belongs to the ABC transporter superfamily
JQ505_RS10100	COG0747	negative chemotaxis
JQ505_RS10105	COG0601	transmembrane transport
JQ505_RS10110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JQ505_RS10130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JQ505_RS10165	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
JQ505_RS10170	COG1797	cobyrinic acid a,c-diamide synthase activity
JQ505_RS10240	COG1028	Short-chain dehydrogenase reductase Sdr
JQ505_RS10255	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JQ505_RS10260	COG0438	transferase activity, transferring glycosyl groups
JQ505_RS10290	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JQ505_RS10295	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JQ505_RS10305	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JQ505_RS10320	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JQ505_RS10325	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
JQ505_RS10345	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JQ505_RS10355	COG2354	Protein conserved in bacteria
JQ505_RS10360	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JQ505_RS10365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JQ505_RS10370	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
JQ505_RS10400	COG0145	ligase activity
JQ505_RS10405	COG4647	ligase activity
JQ505_RS10410	COG0145	ligase activity
JQ505_RS10425	COG3284	Transcriptional regulator
JQ505_RS10445	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JQ505_RS10455	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JQ505_RS10465	COG3485	protocatechuate 3,4-dioxygenase
JQ505_RS10475	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JQ505_RS10490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JQ505_RS10505	COG0352	thiamine-phosphate diphosphorylase activity
JQ505_RS10520	COG2022	thiamine diphosphate biosynthetic process
JQ505_RS10525	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JQ505_RS10530	COG0235	Class ii aldolase
JQ505_RS10535	COG1396	sequence-specific DNA binding
JQ505_RS10540	COG1131	(ABC) transporter
JQ505_RS10550	COG2234	aminopeptidase activity
JQ505_RS10560	COG0351	phosphomethylpyrimidine kinase
JQ505_RS10565	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
JQ505_RS10600	COG2032	superoxide dismutase activity
JQ505_RS10605	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
JQ505_RS10615	COG1320	monovalent cation:proton antiporter activity
JQ505_RS10630	COG0651	ATP synthesis coupled electron transport
JQ505_RS10635	COG1006	Multisubunit Na H antiporter MnhC subunit
JQ505_RS10640	COG2111	Na H antiporter
JQ505_RS10640	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JQ505_RS10645	COG2816	NAD+ diphosphatase activity
JQ505_RS10655	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JQ505_RS10665	COG0688	phosphatidylethanolamine metabolic process
JQ505_RS10685	COG2986	histidine ammonia-lyase
JQ505_RS10690	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JQ505_RS10700	COG1228	amidohydrolase
JQ505_RS10705	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
JQ505_RS10710	COG0326	Molecular chaperone. Has ATPase activity
JQ505_RS10715	COG0647	UMP catabolic process
JQ505_RS10760	COG2267	carboxylic ester hydrolase activity
JQ505_RS10765	COG1505	serine-type exopeptidase activity
JQ505_RS10805	COG0702	epimerase
JQ505_RS10825	COG1802	Transcriptional regulator
JQ505_RS10835	COG1802	Transcriptional regulator
JQ505_RS10875	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JQ505_RS10875	COG1017	nitric oxide dioxygenase activity
JQ505_RS10880	COG2224	Isocitrate lyase
JQ505_RS10890	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JQ505_RS10895	COG1064	alcohol dehydrogenase
JQ505_RS10955	COG3707	response regulator
JQ505_RS10960	COG0693	protein deglycase activity
JQ505_RS10965	COG0723	plastoquinol--plastocyanin reductase activity
JQ505_RS10980	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JQ505_RS10980	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
JQ505_RS11010	COG2890	protein-(glutamine-N5) methyltransferase activity
JQ505_RS11035	COG1028	Short-chain dehydrogenase reductase Sdr
JQ505_RS11050	COG2326	polyphosphate kinase activity
JQ505_RS11065	COG2733	membrane
JQ505_RS11090	COG2267	carboxylic ester hydrolase activity
JQ505_RS11100	COG0788	formyltetrahydrofolate deformylase activity
JQ505_RS11110	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JQ505_RS11135	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JQ505_RS11165	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JQ505_RS11205	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JQ505_RS11225	COG1733	regulation of RNA biosynthetic process
JQ505_RS11230	COG0438	transferase activity, transferring glycosyl groups
JQ505_RS11240	COG1652	LysM domain
JQ505_RS11255	COG0318	PFAM AMP-dependent synthetase and ligase
JQ505_RS11260	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JQ505_RS11270	COG0588	phosphoglycerate mutase activity
JQ505_RS11275	COG5002	protein histidine kinase activity
JQ505_RS11280	COG0745	RESPONSE REGULATOR receiver
JQ505_RS11300	COG1082	Xylose isomerase domain protein TIM barrel
JQ505_RS11355	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JQ505_RS11360	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JQ505_RS11365	COG0181	hydroxymethylbilane synthase activity
JQ505_RS11370	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JQ505_RS11370	COG1648	precorrin-2 dehydrogenase activity
JQ505_RS11390	COG1937	Protein conserved in bacteria
JQ505_RS11395	COG2133	pyrroloquinoline quinone binding
JQ505_RS11415	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
JQ505_RS11430	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JQ505_RS11435	COG0406	alpha-ribazole phosphatase activity
JQ505_RS11445	COG0785	Cytochrome C biogenesis protein
JQ505_RS11455	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JQ505_RS11500	COG1950	PFAM Membrane protein of
JQ505_RS11575	COG4948	Mandelate Racemase Muconate Lactonizing
JQ505_RS11590	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JQ505_RS11595	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
JQ505_RS11605	COG0438	transferase activity, transferring glycosyl groups
JQ505_RS11610	COG2226	methyltransferase
JQ505_RS11620	COG0142	geranyltranstransferase activity
JQ505_RS11625	COG0501	Belongs to the peptidase M48B family
JQ505_RS11630	COG1666	GTP binding
JQ505_RS11655	COG2030	dehydratase
JQ505_RS11670	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JQ505_RS11685	COG0081	regulation of translation
JQ505_RS11705	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JQ505_RS11710	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JQ505_RS11765	COG4607	ABC-type enterochelin transport system periplasmic component
JQ505_RS11785	COG0477	Major facilitator Superfamily
JQ505_RS11805	COG0723	plastoquinol--plastocyanin reductase activity
JQ505_RS11810	COG2149	membrane
JQ505_RS11820	COG2226	methyltransferase
JQ505_RS11830	COG0583	DNA-binding transcription factor activity
JQ505_RS11835	COG0477	Major facilitator Superfamily
JQ505_RS11840	COG5006	permease, DMT superfamily
JQ505_RS11860	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JQ505_RS11875	COG1024	Enoyl-CoA hydratase
JQ505_RS11880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JQ505_RS11885	COG1309	transcriptional regulator
JQ505_RS11905	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JQ505_RS11910	COG0049	tRNA binding
JQ505_RS11920	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JQ505_RS11945	COG1302	Protein conserved in bacteria
JQ505_RS11955	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JQ505_RS11985	COG0542	response to heat
JQ505_RS12005	COG1454	alcohol dehydrogenase
JQ505_RS12015	COG2197	response regulator
JQ505_RS12030	COG1733	regulation of RNA biosynthetic process
JQ505_RS12040	COG1131	(ABC) transporter
JQ505_RS12045	COG3559	Exporter of polyketide antibiotics
JQ505_RS12065	COG0535	radical SAM domain protein
JQ505_RS12080	COG0446	pyridine nucleotide-disulphide oxidoreductase
JQ505_RS12080	COG1902	pentaerythritol trinitrate reductase activity
JQ505_RS12090	COG1902	pentaerythritol trinitrate reductase activity
JQ505_RS12090	COG0446	pyridine nucleotide-disulphide oxidoreductase
JQ505_RS12105	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
JQ505_RS12110	COG0456	acetyltransferase
JQ505_RS12115	COG3135	benzoate transporter
JQ505_RS12120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JQ505_RS12160	COG4941	Belongs to the sigma-70 factor family
JQ505_RS12165	COG3795	YCII-related domain
JQ505_RS12240	COG0531	amino acid
JQ505_RS12245	COG4303	Ethanolamine ammonia lyase large subunit
JQ505_RS12265	COG0477	Major facilitator Superfamily
JQ505_RS12270	COG0318	PFAM AMP-dependent synthetase and ligase
JQ505_RS12280	COG1012	belongs to the aldehyde dehydrogenase family
JQ505_RS12300	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JQ505_RS12310	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS12335	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JQ505_RS12355	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JQ505_RS12365	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JQ505_RS12405	COG0154	amidase activity
JQ505_RS12410	COG0051	transcription antitermination factor activity, RNA binding
JQ505_RS12420	COG0088	Forms part of the polypeptide exit tunnel
JQ505_RS12425	COG0089	rRNA binding
JQ505_RS12430	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JQ505_RS12435	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JQ505_RS12445	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JQ505_RS12460	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JQ505_RS12465	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JQ505_RS12470	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JQ505_RS12475	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JQ505_RS12480	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JQ505_RS12485	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JQ505_RS12490	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JQ505_RS12495	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JQ505_RS12500	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JQ505_RS12520	COG0563	adenylate kinase activity
JQ505_RS12535	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JQ505_RS12540	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JQ505_RS12560	COG0202	RNA polymerase activity
JQ505_RS12565	COG0203	ribosomal protein L17
JQ505_RS12570	COG0101	tRNA pseudouridine synthase activity
JQ505_RS12585	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS12610	COG1404	Belongs to the peptidase S8 family
JQ505_RS12620	COG1674	ftsk spoiiie
JQ505_RS12645	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JQ505_RS12675	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JQ505_RS12685	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JQ505_RS12690	COG2267	carboxylic ester hydrolase activity
JQ505_RS12705	COG0456	acetyltransferase
JQ505_RS12710	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JQ505_RS12720	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JQ505_RS12725	COG0459	protein refolding
JQ505_RS12760	COG0516	GMP reductase activity
JQ505_RS12770	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JQ505_RS12770	COG0519	Catalyzes the synthesis of GMP from XMP
JQ505_RS12780	COG1983	PspC domain protein
JQ505_RS12795	COG0789	Transcriptional regulator
JQ505_RS12850	COG4221	oxidoreductase activity
JQ505_RS12860	COG3559	Exporter of polyketide antibiotics
JQ505_RS12865	COG1131	(ABC) transporter
JQ505_RS12885	COG0640	Transcriptional regulator
JQ505_RS12900	COG1595	DNA-templated transcription, initiation
JQ505_RS12905	COG0587	DNA-directed DNA polymerase activity
JQ505_RS12930	COG1595	DNA-templated transcription, initiation
JQ505_RS12935	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
JQ505_RS12940	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JQ505_RS12945	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JQ505_RS12955	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JQ505_RS12960	COG2873	o-acetylhomoserine
JQ505_RS12970	COG0708	Exodeoxyribonuclease III
JQ505_RS12975	COG0180	Tryptophanyl-tRNA synthetase
JQ505_RS12980	COG1295	ribonuclease BN
JQ505_RS12985	COG1309	transcriptional regulator
JQ505_RS12990	COG2130	NADP-dependent
JQ505_RS12995	COG1064	alcohol dehydrogenase
JQ505_RS13000	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JQ505_RS13015	COG2009	succinate dehydrogenase
JQ505_RS13060	COG0791	NLP P60 protein
JQ505_RS13085	COG1174	glycine betaine transport
JQ505_RS13095	COG1174	glycine betaine transport
JQ505_RS13100	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JQ505_RS13110	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JQ505_RS13130	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
JQ505_RS13130	COG1473	amidohydrolase
JQ505_RS13135	COG1840	ABC-type Fe3 transport system, periplasmic component
JQ505_RS13145	COG3842	ATPase activity
JQ505_RS13170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JQ505_RS13175	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JQ505_RS13200	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JQ505_RS13205	COG1201	RNA secondary structure unwinding
JQ505_RS13215	COG0277	FAD linked oxidase domain protein
JQ505_RS13220	COG0318	PFAM AMP-dependent synthetase and ligase
JQ505_RS13245	COG1012	belongs to the aldehyde dehydrogenase family
JQ505_RS13250	COG1522	sequence-specific DNA binding
JQ505_RS13290	COG4770	biotin carboxylase activity
JQ505_RS13320	COG2226	methyltransferase
JQ505_RS13335	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JQ505_RS13340	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
JQ505_RS13340	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
JQ505_RS13350	COG0745	RESPONSE REGULATOR receiver
JQ505_RS13355	COG2205	protein histidine kinase activity
JQ505_RS13365	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JQ505_RS13375	COG4585	Histidine kinase
JQ505_RS13380	COG2197	response regulator
JQ505_RS13385	COG1136	(ABC) transporter
JQ505_RS13390	COG1136	(ABC) transporter
JQ505_RS13390	COG0577	efflux transmembrane transporter activity
JQ505_RS13405	COG1316	TRANSCRIPTIONal
JQ505_RS13420	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JQ505_RS13425	COG2755	lipolytic protein G-D-S-L family
JQ505_RS13435	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
JQ505_RS13435	COG0778	Nitroreductase
JQ505_RS13460	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JQ505_RS13470	COG1482	cell wall glycoprotein biosynthetic process
JQ505_RS13475	COG0531	amino acid
JQ505_RS13495	COG0745	RESPONSE REGULATOR receiver
JQ505_RS13505	COG5401	PFAM Sporulation and spore germination
JQ505_RS13515	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JQ505_RS13530	COG1011	Hydrolase
JQ505_RS13560	COG1162	GTPase activity
JQ505_RS13565	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JQ505_RS13575	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JQ505_RS13590	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
JQ505_RS13605	COG1597	lipid kinase activity
JQ505_RS13630	COG0513	Belongs to the DEAD box helicase family
JQ505_RS13665	COG2186	Transcriptional regulator
JQ505_RS13680	COG2146	nitrite reductase [NAD(P)H] activity
JQ505_RS13680	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JQ505_RS13700	COG1289	transmembrane transporter activity
JQ505_RS13710	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JQ505_RS13715	COG3695	enzyme binding
JQ505_RS13720	COG0596	Alpha beta hydrolase
JQ505_RS13765	COG1028	Short-chain dehydrogenase reductase Sdr
JQ505_RS13785	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JQ505_RS13800	COG3480	Lon protease (S16) C-terminal proteolytic domain
JQ505_RS13820	COG0318	PFAM AMP-dependent synthetase and ligase
JQ505_RS13830	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS13840	COG0483	inositol monophosphate 1-phosphatase activity
JQ505_RS13845	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
JQ505_RS13850	COG0668	transmembrane transport
JQ505_RS13860	COG2884	Cell division ATP-binding protein ftsE
JQ505_RS13865	COG2177	Part of the ABC transporter FtsEX involved in
JQ505_RS13870	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JQ505_RS13885	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JQ505_RS13890	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JQ505_RS13935	COG1414	Transcriptional regulator
JQ505_RS13940	COG2124	cytochrome p450
JQ505_RS13960	COG2271	Major facilitator Superfamily
JQ505_RS13965	COG2197	response regulator
JQ505_RS13970	COG3265	gluconokinase activity
JQ505_RS13990	COG0523	cobalamin synthesis protein
JQ505_RS13995	COG0513	Belongs to the DEAD box helicase family
JQ505_RS14000	COG0314	molybdopterin synthase activity
JQ505_RS14005	COG0521	Mo-molybdopterin cofactor biosynthetic process
JQ505_RS14005	COG0315	cyclic pyranopterin monophosphate synthase activity
JQ505_RS14015	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JQ505_RS14045	COG1309	transcriptional regulator
JQ505_RS14055	COG2080	2 iron, 2 sulfur cluster binding
JQ505_RS14060	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
JQ505_RS14065	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JQ505_RS14075	COG1780	Probably involved in ribonucleotide reductase function
JQ505_RS14105	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JQ505_RS14110	COG0560	Phosphoserine phosphatase
JQ505_RS14110	COG3830	Belongs to the UPF0237 family
JQ505_RS14125	COG1119	ATPase activity
JQ505_RS14140	COG2226	methyltransferase
JQ505_RS14150	COG0640	Transcriptional regulator
JQ505_RS14155	COG0346	lactoylglutathione lyase activity
JQ505_RS14165	COG0110	maltose O-acetyltransferase activity
JQ505_RS14185	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JQ505_RS14195	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
JQ505_RS14215	COG0482	sulfurtransferase activity
JQ505_RS14225	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JQ505_RS14230	COG0456	acetyltransferase
JQ505_RS14240	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JQ505_RS14245	COG0154	amidase activity
JQ505_RS14260	COG4585	Histidine kinase
JQ505_RS14275	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JQ505_RS14300	COG0129	dihydroxy-acid dehydratase activity
JQ505_RS14315	COG0440	acetolactate synthase activity
JQ505_RS14320	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JQ505_RS14340	COG2271	Major facilitator Superfamily
JQ505_RS14345	COG0179	Fumarylacetoacetate (FAA) hydrolase
JQ505_RS14350	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JQ505_RS14380	COG1414	Transcriptional regulator
JQ505_RS14385	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JQ505_RS14390	COG0066	3-isopropylmalate dehydratase activity
JQ505_RS14405	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JQ505_RS14410	COG1920	GTP binding
JQ505_RS14415	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JQ505_RS14420	COG0626	cystathionine gamma-synthase activity
JQ505_RS14425	COG1181	Belongs to the D-alanine--D-alanine ligase family
JQ505_RS14430	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JQ505_RS14435	COG0542	response to heat
JQ505_RS14445	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JQ505_RS14450	COG0799	negative regulation of ribosome biogenesis
JQ505_RS14455	COG0406	alpha-ribazole phosphatase activity
JQ505_RS14460	COG2755	lipolytic protein G-D-S-L family
JQ505_RS14485	COG0268	Binds directly to 16S ribosomal RNA
JQ505_RS14500	COG1305	Transglutaminase-like
JQ505_RS14505	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JQ505_RS14515	COG0481	GTPase activity
JQ505_RS14520	COG2070	2-Nitropropane dioxygenase
JQ505_RS14525	COG3387	PFAM Glycoside hydrolase 15-related
JQ505_RS14540	COG0589	response to stress
JQ505_RS14580	COG1420	regulation of RNA biosynthetic process
JQ505_RS14585	COG0484	heat shock protein binding
JQ505_RS14605	COG0477	Major facilitator Superfamily
JQ505_RS14655	COG1335	isochorismatase
JQ505_RS14660	COG3069	C4-dicarboxylate transmembrane transporter activity
JQ505_RS14665	COG1381	Involved in DNA repair and RecF pathway recombination
JQ505_RS14670	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JQ505_RS14695	COG0423	glycine-tRNA ligase activity
JQ505_RS14735	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JQ505_RS14745	COG1595	DNA-templated transcription, initiation
JQ505_RS14755	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
JQ505_RS14785	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JQ505_RS14800	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
JQ505_RS14910	COG0557	exoribonuclease II activity
JQ505_RS14930	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JQ505_RS14940	COG0174	glutamine synthetase
JQ505_RS14945	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
JQ505_RS14950	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
JQ505_RS14975	COG0531	amino acid
JQ505_RS14995	COG0174	glutamine synthetase
JQ505_RS15010	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JQ505_RS15015	COG0321	lipoyl(octanoyl) transferase activity
JQ505_RS15030	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JQ505_RS15035	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JQ505_RS15040	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JQ505_RS15045	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
JQ505_RS15050	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
JQ505_RS15070	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JQ505_RS15080	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JQ505_RS15105	COG1845	cytochrome c oxidase, subunit III
JQ505_RS15115	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JQ505_RS15130	COG0791	NLP P60 protein
JQ505_RS15145	COG0438	transferase activity, transferring glycosyl groups
JQ505_RS15160	COG0003	Pfam Anion-transporting ATPase
JQ505_RS15170	COG1940	carbohydrate kinase activity
JQ505_RS15185	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
JQ505_RS15215	COG0142	geranyltranstransferase activity
JQ505_RS15225	COG0463	Glycosyl transferase, family 2
JQ505_RS15260	COG2001	Belongs to the MraZ family
JQ505_RS15265	COG0275	rRNA processing
JQ505_RS15275	COG0768	penicillin binding
JQ505_RS15295	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JQ505_RS15310	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JQ505_RS15315	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JQ505_RS15320	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JQ505_RS15335	COG1799	cell septum assembly
JQ505_RS15345	COG3599	regulation of cell shape
JQ505_RS15355	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JQ505_RS15375	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JQ505_RS15420	COG2197	response regulator
JQ505_RS15430	COG2409	Drug exporters of the RND superfamily
JQ505_RS15435	COG2124	cytochrome p450
JQ505_RS15440	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JQ505_RS15445	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JQ505_RS15455	COG0028	Belongs to the TPP enzyme family
JQ505_RS15475	COG0477	Major facilitator Superfamily
JQ505_RS15510	COG3012	SEC-C Motif Domain Protein
JQ505_RS15580	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JQ505_RS15585	COG0156	8-amino-7-oxononanoate synthase activity
JQ505_RS15590	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
JQ505_RS15595	COG2208	phosphoserine phosphatase activity
JQ505_RS15595	COG2770	Histidine kinase
JQ505_RS15630	COG1053	succinate dehydrogenase
JQ505_RS15645	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
JQ505_RS15675	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
JQ505_RS15700	COG1280	lysine exporter protein (LysE YggA)
JQ505_RS15705	COG2723	6-phospho-beta-galactosidase activity
JQ505_RS15720	COG3243	poly(R)-hydroxyalkanoic acid synthase
JQ505_RS15730	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JQ505_RS15740	COG0131	Imidazoleglycerol-phosphate dehydratase
JQ505_RS15755	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JQ505_RS15765	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JQ505_RS15770	COG0483	inositol monophosphate 1-phosphatase activity
JQ505_RS15775	COG0107	imidazoleglycerol-phosphate synthase activity
JQ505_RS15810	COG3384	dioxygenase
JQ505_RS15820	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JQ505_RS15830	COG0134	indole-3-glycerol-phosphate synthase activity
JQ505_RS15840	COG0159	tryptophan synthase activity
JQ505_RS15845	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JQ505_RS15855	COG0067	glutamate synthase
JQ505_RS15855	COG0069	glutamate synthase activity
JQ505_RS15855	COG0070	glutamate synthase
JQ505_RS15880	COG0783	Belongs to the Dps family
JQ505_RS15885	COG0789	Transcriptional regulator
JQ505_RS15895	COG1946	Acyl-CoA thioesterase
JQ505_RS15905	COG0604	alcohol dehydrogenase
JQ505_RS15920	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JQ505_RS15925	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JQ505_RS15930	COG0022	dehydrogenase e1 component
JQ505_RS15930	COG0508	dehydrogenase complex catalyzes the overall conversion of
JQ505_RS15960	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JQ505_RS16010	COG1172	Belongs to the binding-protein-dependent transport system permease family
JQ505_RS16020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JQ505_RS16025	COG4977	sequence-specific DNA binding
JQ505_RS16035	COG0473	3-isopropylmalate dehydrogenase activity
JQ505_RS16045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JQ505_RS16060	COG0318	PFAM AMP-dependent synthetase and ligase
JQ505_RS16065	COG3548	integral membrane protein
JQ505_RS16070	COG2226	methyltransferase
JQ505_RS16075	COG0539	negative regulation of cytoplasmic translation
JQ505_RS16085	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JQ505_RS16085	COG0237	dephospho-CoA kinase activity
JQ505_RS16140	COG0659	secondary active sulfate transmembrane transporter activity
JQ505_RS16155	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JQ505_RS16160	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JQ505_RS16165	COG0649	NAD binding
JQ505_RS16180	COG1034	ATP synthesis coupled electron transport
JQ505_RS16185	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
JQ505_RS16190	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JQ505_RS16190	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
JQ505_RS16200	COG0713	ATP synthesis coupled electron transport
JQ505_RS16225	COG3540	Alkaline phosphatase
JQ505_RS16265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JQ505_RS16275	COG2267	carboxylic ester hydrolase activity
JQ505_RS16285	COG0589	response to stress
JQ505_RS16295	COG1012	belongs to the aldehyde dehydrogenase family
JQ505_RS16300	COG3321	synthase
JQ505_RS16300	COG0604	alcohol dehydrogenase
JQ505_RS16325	COG0469	pyruvate kinase activity
JQ505_RS16345	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JQ505_RS16355	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JQ505_RS16360	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JQ505_RS16360	COG0072	phenylalanine-tRNA ligase activity
JQ505_RS16370	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JQ505_RS16375	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JQ505_RS16380	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JQ505_RS16390	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JQ505_RS16395	COG1438	arginine binding
JQ505_RS16405	COG0165	Argininosuccinate lyase
JQ505_RS16420	COG2094	Belongs to the DNA glycosylase MPG family
JQ505_RS16425	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JQ505_RS16450	COG0647	UMP catabolic process
JQ505_RS16465	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JQ505_RS16490	COG0494	nUDIX hydrolase
JQ505_RS16510	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JQ505_RS16520	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JQ505_RS16525	COG1160	GTP binding
JQ505_RS16535	COG1012	belongs to the aldehyde dehydrogenase family
JQ505_RS16535	COG1454	alcohol dehydrogenase
JQ505_RS16560	COG0494	nUDIX hydrolase
JQ505_RS16590	COG1716	ATPase activity
JQ505_RS16615	COG1408	metallophosphoesterase
JQ505_RS16625	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
JQ505_RS16635	COG0277	FAD linked oxidase domain protein
JQ505_RS16650	COG1253	flavin adenine dinucleotide binding
JQ505_RS16655	COG1253	flavin adenine dinucleotide binding
JQ505_RS16665	COG0697	spore germination
JQ505_RS16670	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JQ505_RS16685	COG1120	ATPase activity
JQ505_RS16690	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JQ505_RS16695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JQ505_RS16710	COG1252	NADH dehydrogenase
JQ505_RS16730	COG0346	lactoylglutathione lyase activity
JQ505_RS16755	COG1605	Chorismate mutase
JQ505_RS16760	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JQ505_RS16760	COG0512	Glutamine amidotransferase of anthranilate synthase
JQ505_RS16765	COG0287	Prephenate dehydrogenase
JQ505_RS16785	COG0463	Glycosyl transferase, family 2
JQ505_RS16795	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JQ505_RS16820	COG0366	Alpha amylase catalytic
JQ505_RS16825	COG0395	ABC-type sugar transport system, permease component
JQ505_RS16840	COG1609	Transcriptional regulator
JQ505_RS16850	COG3842	ATPase activity
JQ505_RS16865	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JQ505_RS16870	COG0300	oxidoreductase activity
JQ505_RS16905	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JQ505_RS16910	COG2378	regulation of single-species biofilm formation
JQ505_RS16920	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
JQ505_RS16930	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
JQ505_RS16990	COG0140	phosphoribosyl-ATP diphosphatase activity
JQ505_RS16995	COG0564	pseudouridine synthase activity
JQ505_RS17005	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JQ505_RS17010	COG0646	methionine synthase
JQ505_RS17010	COG1410	methionine synthase
JQ505_RS17020	COG2814	Major facilitator Superfamily
JQ505_RS17025	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JQ505_RS17030	COG2146	nitrite reductase [NAD(P)H] activity
JQ505_RS17050	COG0492	ferredoxin-NADP+ reductase activity
JQ505_RS17080	COG0657	acetylesterase activity
JQ505_RS17095	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JQ505_RS17110	COG1024	Enoyl-CoA hydratase
JQ505_RS17120	COG1012	belongs to the aldehyde dehydrogenase family
JQ505_RS17125	COG2072	flavoprotein involved in K transport
JQ505_RS17130	COG1607	acyl-coa hydrolase
JQ505_RS17155	COG0215	cysteine-tRNA ligase activity
JQ505_RS17175	COG1968	undecaprenyl-diphosphatase activity
JQ505_RS17180	COG0667	Aldo Keto reductase
JQ505_RS17185	COG5398	heme oxygenase
JQ505_RS17195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JQ505_RS17200	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
JQ505_RS17230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JQ505_RS17265	COG3268	Saccharopine dehydrogenase
JQ505_RS17270	COG0730	response to heat
JQ505_RS17275	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JQ505_RS17330	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JQ505_RS17340	COG1028	Short-chain dehydrogenase reductase Sdr
JQ505_RS17345	COG2304	oxidoreductase activity
JQ505_RS17355	COG0714	Associated with various cellular activities
JQ505_RS17360	COG3883	PFAM NLP P60 protein
JQ505_RS17360	COG0791	NLP P60 protein
JQ505_RS17370	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JQ505_RS17375	COG1309	transcriptional regulator
JQ505_RS17400	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
JQ505_RS17425	COG0396	ATPase activity
JQ505_RS17450	COG1131	(ABC) transporter
JQ505_RS17475	COG0109	protoheme IX farnesyltransferase activity
JQ505_RS17485	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JQ505_RS17520	COG2015	COG2015, Alkyl sulfatase and related hydrolases
JQ505_RS17530	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
JQ505_RS17540	COG0149	triose-phosphate isomerase activity
JQ505_RS17545	COG0126	phosphoglycerate kinase activity
JQ505_RS17550	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JQ505_RS17555	COG1481	regulation of sporulation
JQ505_RS17565	COG1660	Displays ATPase and GTPase activities
JQ505_RS17570	COG0322	excinuclease ABC activity
JQ505_RS17585	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JQ505_RS17585	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JQ505_RS17640	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JQ505_RS17650	COG1758	RNA polymerase activity
JQ505_RS17655	COG0194	GDP metabolic process
JQ505_RS17665	COG0284	orotidine-5'-phosphate decarboxylase activity
JQ505_RS17675	COG0505	Belongs to the CarA family
JQ505_RS17690	COG0540	Belongs to the ATCase OTCase family
JQ505_RS17695	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JQ505_RS17700	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JQ505_RS17705	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JQ505_RS17710	COG0006	proline dipeptidase activity
JQ505_RS17735	COG0640	Transcriptional regulator
JQ505_RS17755	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JQ505_RS17760	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JQ505_RS17775	COG4941	Belongs to the sigma-70 factor family
JQ505_RS17795	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JQ505_RS17805	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JQ505_RS17810	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JQ505_RS17855	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JQ505_RS17915	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JQ505_RS17935	COG0789	Transcriptional regulator
JQ505_RS17960	COG2072	flavoprotein involved in K transport
JQ505_RS17965	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
JQ505_RS17965	COG4124	Belongs to the glycosyl hydrolase 26 family
JQ505_RS17970	COG2208	phosphoserine phosphatase activity
JQ505_RS17980	COG1366	Belongs to the anti-sigma-factor antagonist family
JQ505_RS17990	COG1113	amino acid transport
JQ505_RS18005	COG1984	allophanate hydrolase subunit 2
JQ505_RS18040	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
JQ505_RS18040	COG2308	Evidence 4 Homologs of previously reported genes of
JQ505_RS18045	COG0367	asparagine synthase
JQ505_RS18050	COG1506	peptidase
JQ505_RS18050	COG0823	Involved in the tonB-independent uptake of proteins
JQ505_RS18050	COG4946	Tricorn protease homolog
JQ505_RS18055	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
JQ505_RS18055	COG1473	amidohydrolase
JQ505_RS18060	COG0484	heat shock protein binding
JQ505_RS18070	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JQ505_RS18090	COG0124	histidyl-tRNA synthetase
JQ505_RS18105	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JQ505_RS18135	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JQ505_RS18140	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JQ505_RS18145	COG0747	negative chemotaxis
JQ505_RS18165	COG2255	four-way junction helicase activity
JQ505_RS18170	COG0632	four-way junction helicase activity
JQ505_RS18175	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
JQ505_RS18185	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
JQ505_RS18195	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
JQ505_RS18200	COG1051	belongs to the nudix hydrolase family
JQ505_RS18205	COG0438	transferase activity, transferring glycosyl groups
JQ505_RS18225	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JQ505_RS18300	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JQ505_RS18320	COG0039	L-malate dehydrogenase activity
JQ505_RS18325	COG3253	May function as heme-dependent peroxidase
JQ505_RS18335	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JQ505_RS18360	COG0183	Belongs to the thiolase family
JQ505_RS18365	COG1024	Enoyl-CoA hydratase
JQ505_RS18365	COG1250	3-hydroxyacyl-CoA dehydrogenase
JQ505_RS18370	COG0477	Major facilitator Superfamily
JQ505_RS18375	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JQ505_RS18390	COG0477	Major facilitator Superfamily
JQ505_RS18395	COG1846	Transcriptional regulator
JQ505_RS18400	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JQ505_RS18405	COG0531	amino acid
JQ505_RS18410	COG0569	domain protein
JQ505_RS18440	COG0756	dUTP diphosphatase activity
JQ505_RS18475	COG0475	glutathione-regulated potassium exporter activity
JQ505_RS18515	COG2890	protein-(glutamine-N5) methyltransferase activity
JQ505_RS18525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JQ505_RS18525	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JQ505_RS18530	COG0123	including yeast histone deacetylase and acetoin utilization protein
JQ505_RS18565	COG4581	dead DEAH box helicase
JQ505_RS18570	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JQ505_RS18610	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JQ505_RS18615	COG1643	Atp-dependent helicase
JQ505_RS18635	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS18640	COG2233	PERMEase
JQ505_RS18645	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JQ505_RS18650	COG1349	DNA-binding transcription factor activity
JQ505_RS18660	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JQ505_RS18660	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JQ505_RS18660	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
JQ505_RS18675	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JQ505_RS18685	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JQ505_RS18695	COG1196	nuclear chromosome segregation
JQ505_RS18705	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JQ505_RS18710	COG1126	abc transporter atp-binding protein
JQ505_RS18715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JQ505_RS18720	COG0765	amino acid transport
JQ505_RS18725	COG0765	amino acid transport
JQ505_RS18730	COG2137	regulation of response to DNA damage stimulus
JQ505_RS18735	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JQ505_RS18785	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
JQ505_RS18800	COG1268	BioY protein
JQ505_RS18805	COG1122	ATPase activity
JQ505_RS18810	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JQ505_RS18820	COG1842	Phage shock protein A
JQ505_RS18825	COG1396	sequence-specific DNA binding
JQ505_RS18830	COG1058	Belongs to the CinA family
JQ505_RS18830	COG1546	Belongs to the CinA family
JQ505_RS18840	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
JQ505_RS18855	COG1674	ftsk spoiiie
JQ505_RS18865	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JQ505_RS18875	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
JQ505_RS18900	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JQ505_RS18905	COG0612	Peptidase, M16
JQ505_RS18920	COG1140	nitrate reductase beta subunit
JQ505_RS18955	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JQ505_RS18970	COG0803	Belongs to the bacterial solute-binding protein 9 family
JQ505_RS18975	COG1121	(ABC) transporter
JQ505_RS18980	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JQ505_RS18990	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JQ505_RS19000	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
JQ505_RS19010	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JQ505_RS19015	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JQ505_RS19025	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JQ505_RS19025	COG0481	GTPase activity
JQ505_RS19055	COG4122	O-methyltransferase activity
JQ505_RS19060	COG0442	prolyl-tRNA aminoacylation
JQ505_RS19065	COG3022	response to hydroperoxide
JQ505_RS19080	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JQ505_RS19080	COG1648	precorrin-2 dehydrogenase activity
JQ505_RS19085	COG0318	PFAM AMP-dependent synthetase and ligase
JQ505_RS19090	COG0579	oxidoreductase
JQ505_RS19115	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JQ505_RS19120	COG2197	response regulator
JQ505_RS19125	COG0768	penicillin binding
JQ505_RS19145	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
JQ505_RS19155	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JQ505_RS19165	COG2301	Belongs to the HpcH HpaI aldolase family
JQ505_RS19175	COG0575	Belongs to the CDS family
JQ505_RS19180	COG0233	cytoplasmic translational termination
JQ505_RS19185	COG0528	UMP kinase activity
JQ505_RS19190	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JQ505_RS19210	COG4974	Belongs to the 'phage' integrase family
JQ505_RS19215	COG2814	Major facilitator Superfamily
JQ505_RS19285	COG0792	nuclease activity
JQ505_RS19300	COG0681	Belongs to the peptidase S26 family
JQ505_RS19325	COG0336	Belongs to the RNA methyltransferase TrmD family
JQ505_RS19330	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JQ505_RS19340	COG0228	four-way junction DNA binding
JQ505_RS19360	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
JQ505_RS19385	COG1254	Belongs to the acylphosphatase family
JQ505_RS19400	COG0583	DNA-binding transcription factor activity
JQ505_RS19405	COG3485	protocatechuate 3,4-dioxygenase
JQ505_RS19410	COG3485	protocatechuate 3,4-dioxygenase
JQ505_RS19420	COG1309	transcriptional regulator
JQ505_RS19425	COG1131	(ABC) transporter
JQ505_RS19440	COG1131	(ABC) transporter
JQ505_RS19470	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JQ505_RS19480	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JQ505_RS19485	COG0571	ribonuclease III activity
JQ505_RS19490	COG0333	Belongs to the bacterial ribosomal protein bL32 family
JQ505_RS19510	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JQ505_RS19515	COG0742	ribosomal rna small subunit methyltransferase
JQ505_RS19520	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
JQ505_RS19525	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JQ505_RS19530	COG1461	Dihydroxyacetone kinase
JQ505_RS19535	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JQ505_RS19540	COG1024	Enoyl-CoA hydratase
JQ505_RS19545	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JQ505_RS19570	COG0514	ATP-dependent DNA helicase (RecQ)
JQ505_RS19575	COG0456	acetyltransferase
JQ505_RS19580	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JQ505_RS19585	COG1917	Cupin 2, conserved barrel domain protein
JQ505_RS19590	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JQ505_RS19605	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JQ505_RS19610	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JQ505_RS19620	COG1530	ribonuclease E activity
JQ505_RS19635	COG0285	dihydrofolate synthase activity
JQ505_RS19640	COG0525	valine-tRNA ligase activity
JQ505_RS19650	COG4946	Tricorn protease homolog
JQ505_RS19650	COG1506	peptidase
JQ505_RS19650	COG0823	Involved in the tonB-independent uptake of proteins
JQ505_RS19690	COG0697	spore germination
JQ505_RS19715	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JQ505_RS19735	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JQ505_RS19740	COG2218	PFAM glutamate synthase alpha subunit domain protein
JQ505_RS19745	COG0069	glutamate synthase activity
JQ505_RS19765	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JQ505_RS19780	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JQ505_RS19785	COG1309	transcriptional regulator
JQ505_RS19790	COG0477	Major facilitator Superfamily
JQ505_RS19800	COG0740	serine-type endopeptidase activity
JQ505_RS19805	COG0740	serine-type endopeptidase activity
JQ505_RS19810	COG0544	peptidyl-prolyl cis-trans isomerase activity
JQ505_RS19840	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JQ505_RS19845	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JQ505_RS19880	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JQ505_RS19895	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
JQ505_RS19915	COG0366	Alpha amylase catalytic
JQ505_RS19930	COG0824	Thioesterase
JQ505_RS19935	COG2902	Dehydrogenase
JQ505_RS19970	COG3336	cytochrome c oxidase
JQ505_RS20145	COG0277	FAD linked oxidase domain protein
JQ505_RS20150	COG1620	l-lactate permease
JQ505_RS20160	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JQ505_RS20180	COG1309	transcriptional regulator
JQ505_RS20185	COG0596	Alpha beta hydrolase
JQ505_RS20215	COG0446	pyridine nucleotide-disulphide oxidoreductase
JQ505_RS20215	COG1902	pentaerythritol trinitrate reductase activity
JQ505_RS20220	COG0300	oxidoreductase activity
JQ505_RS20225	COG0433	COG0433 Predicted ATPase
JQ505_RS20230	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
JQ505_RS20245	COG1376	ErfK ybiS ycfS ynhG family protein
JQ505_RS20280	COG1376	ErfK ybiS ycfS ynhG family protein
JQ505_RS20300	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JQ505_RS20310	COG0736	holo-[acyl-carrier-protein] synthase activity
JQ505_RS20335	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JQ505_RS20340	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
JQ505_RS20345	COG1234	tRNA 3'-trailer cleavage
JQ505_RS20370	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
JQ505_RS20375	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JQ505_RS20380	COG1335	isochorismatase
JQ505_RS20420	COG0596	Alpha beta hydrolase
JQ505_RS20430	COG0058	SHG alpha-glucan phosphorylase activity
JQ505_RS20435	COG0366	Alpha amylase catalytic
JQ505_RS20440	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JQ505_RS20455	COG2409	Drug exporters of the RND superfamily
JQ505_RS20460	COG0183	Belongs to the thiolase family
JQ505_RS20465	COG0346	lactoylglutathione lyase activity
JQ505_RS20480	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
JQ505_RS20505	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JQ505_RS20525	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JQ505_RS20530	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JQ505_RS20535	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JQ505_RS20540	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JQ505_RS20545	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JQ505_RS20550	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JQ505_RS20555	COG0356	it plays a direct role in the translocation of protons across the membrane
JQ505_RS20565	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JQ505_RS20575	COG2890	protein-(glutamine-N5) methyltransferase activity
JQ505_RS20585	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JQ505_RS20590	COG0254	rRNA binding
JQ505_RS20605	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JQ505_RS20610	COG0460	homoserine dehydrogenase
JQ505_RS20615	COG0019	diaminopimelate decarboxylase activity
JQ505_RS20620	COG0018	arginyl-trna synthetase
JQ505_RS20635	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
JQ505_RS20660	COG1218	3'(2'),5'-bisphosphate nucleotidase
JQ505_RS20695	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JQ505_RS20715	COG1024	Enoyl-CoA hydratase
JQ505_RS20735	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JQ505_RS20750	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JQ505_RS20760	COG3135	benzoate transporter
JQ505_RS20770	COG0183	Belongs to the thiolase family
JQ505_RS20785	COG0022	dehydrogenase e1 component
JQ505_RS20790	COG0508	dehydrogenase complex catalyzes the overall conversion of
JQ505_RS20815	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
JQ505_RS20820	COG3189	MarR family transcriptional regulator
JQ505_RS20830	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JQ505_RS20870	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JQ505_RS20905	COG2272	Belongs to the type-B carboxylesterase lipase family
JQ505_RS20910	COG0352	thiamine-phosphate diphosphorylase activity
JQ505_RS20910	COG0351	phosphomethylpyrimidine kinase
JQ505_RS20910	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JQ505_RS20915	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JQ505_RS20920	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JQ505_RS20925	COG1116	anion transmembrane transporter activity
JQ505_RS20935	COG0657	acetylesterase activity
JQ505_RS20955	COG2197	response regulator
JQ505_RS20965	COG1022	Amp-dependent synthetase and ligase
JQ505_RS20985	COG0183	Belongs to the thiolase family
JQ505_RS21030	COG2326	polyphosphate kinase activity
JQ505_RS21040	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JQ505_RS21050	COG4552	Acetyltransferase involved in intracellular survival and related
JQ505_RS21085	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JQ505_RS21085	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JQ505_RS21095	COG0431	NADPH-dependent FMN reductase
JQ505_RS21100	COG1172	Belongs to the binding-protein-dependent transport system permease family
JQ505_RS21115	COG1335	isochorismatase
JQ505_RS21120	COG2814	Major facilitator Superfamily
JQ505_RS21125	COG0154	amidase activity
JQ505_RS21135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JQ505_RS21140	COG1609	Transcriptional regulator
JQ505_RS21345	COG1414	Transcriptional regulator
JQ505_RS21350	COG3971	2-oxopent-4-enoate hydratase activity
JQ505_RS21385	COG0346	lactoylglutathione lyase activity
JQ505_RS21400	COG2508	Transcriptional regulator
JQ505_RS21400	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
JQ505_RS21410	COG1414	Transcriptional regulator
JQ505_RS21415	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JQ505_RS21420	COG0318	PFAM AMP-dependent synthetase and ligase
JQ505_RS21440	COG3485	protocatechuate 3,4-dioxygenase
JQ505_RS21445	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
JQ505_RS21455	COG1832	CoA-binding protein
JQ505_RS21480	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JQ505_RS21500	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
JQ505_RS21525	COG0492	ferredoxin-NADP+ reductase activity
JQ505_RS21530	COG0505	Belongs to the CarA family
JQ505_RS21550	COG2313	pseudouridylate synthase activity
JQ505_RS21595	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JQ505_RS21630	COG0439	Biotin carboxylase
JQ505_RS21640	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JQ505_RS21655	COG0477	Major facilitator Superfamily
JQ505_RS21660	COG0583	DNA-binding transcription factor activity
JQ505_RS21670	COG2267	carboxylic ester hydrolase activity
JQ505_RS21680	COG1028	Short-chain dehydrogenase reductase Sdr
JQ505_RS21720	COG1335	isochorismatase
JQ505_RS21725	COG1063	alcohol dehydrogenase
JQ505_RS21740	COG0179	Fumarylacetoacetate (FAA) hydrolase
JQ505_RS21750	COG1414	Transcriptional regulator
JQ505_RS21755	COG2814	Major facilitator Superfamily
JQ505_RS21760	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JQ505_RS21765	COG0579	oxidoreductase
JQ505_RS21770	COG0519	Catalyzes the synthesis of GMP from XMP
JQ505_RS21770	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JQ505_RS21805	COG0477	Major facilitator Superfamily
JQ505_RS21815	COG0477	Major facilitator Superfamily
JQ505_RS21825	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JQ505_RS21835	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JQ505_RS21840	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS21845	COG0583	DNA-binding transcription factor activity
JQ505_RS21870	COG3550	peptidyl-serine autophosphorylation
JQ505_RS21885	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JQ505_RS21890	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JQ505_RS21895	COG1929	Belongs to the glycerate kinase type-1 family
JQ505_RS21910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JQ505_RS21915	COG0657	acetylesterase activity
JQ505_RS21935	COG1309	transcriptional regulator
JQ505_RS21965	COG2945	thiolester hydrolase activity
JQ505_RS21965	COG0596	Alpha beta hydrolase
JQ505_RS21975	COG0596	Alpha beta hydrolase
JQ505_RS21995	COG1136	(ABC) transporter
JQ505_RS21995	COG0577	efflux transmembrane transporter activity
JQ505_RS22000	COG0577	efflux transmembrane transporter activity
JQ505_RS22000	COG1136	(ABC) transporter
JQ505_RS22005	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
JQ505_RS22015	COG3467	pyridoxamine 5'-phosphate
JQ505_RS22020	COG1132	(ABC) transporter
JQ505_RS22025	COG2318	DinB family
JQ505_RS22050	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
JQ505_RS22095	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JQ505_RS22100	COG1024	Enoyl-CoA hydratase
JQ505_RS22105	COG0318	PFAM AMP-dependent synthetase and ligase
JQ505_RS22125	COG0435	Glutathione S-transferase
JQ505_RS22145	COG0596	Alpha beta hydrolase
JQ505_RS22165	COG0567	Dehydrogenase, E1 component
JQ505_RS22165	COG0508	dehydrogenase complex catalyzes the overall conversion of
JQ505_RS22170	COG1309	transcriptional regulator
JQ505_RS22175	COG2072	flavoprotein involved in K transport
JQ505_RS22205	COG0613	PHP domain protein
JQ505_RS22210	COG0598	Magnesium transport protein CorA
JQ505_RS22230	COG0514	ATP-dependent DNA helicase (RecQ)
JQ505_RS22245	COG0477	Major facilitator Superfamily
JQ505_RS22280	COG2301	Belongs to the HpcH HpaI aldolase family
JQ505_RS22285	COG2239	Acts as a magnesium transporter
JQ505_RS22315	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JQ505_RS22320	COG5662	AntiSigma factor
JQ505_RS22325	COG1595	DNA-templated transcription, initiation
JQ505_RS22330	COG4122	O-methyltransferase activity
JQ505_RS22335	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JQ505_RS22340	COG0297	glycogen (starch) synthase activity
JQ505_RS22355	COG0519	Catalyzes the synthesis of GMP from XMP
JQ505_RS22365	COG0463	Glycosyl transferase, family 2
JQ505_RS22370	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JQ505_RS22375	COG0318	PFAM AMP-dependent synthetase and ligase
JQ505_RS22380	COG1611	Belongs to the LOG family
JQ505_RS22385	COG1611	Belongs to the LOG family
JQ505_RS22390	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JQ505_RS22395	COG2171	N-acyltransferase activity
JQ505_RS22400	COG1113	amino acid transport
JQ505_RS22425	COG0506	proline dehydrogenase activity
JQ505_RS22430	COG1012	belongs to the aldehyde dehydrogenase family
JQ505_RS22450	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
JQ505_RS22485	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JQ505_RS22490	COG0747	negative chemotaxis
JQ505_RS22495	COG1217	gtp-binding protein TYPA
JQ505_RS22510	COG2154	pterin-4-alpha-carbinolamine dehydratase
JQ505_RS22515	COG1051	belongs to the nudix hydrolase family
JQ505_RS22530	COG0477	Major facilitator Superfamily
JQ505_RS22535	COG3757	hydrolase, family 25
JQ505_RS22575	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
JQ505_RS22575	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
JQ505_RS22595	COG1595	DNA-templated transcription, initiation
JQ505_RS22605	COG4569	acetaldehyde dehydrogenase (acetylating) activity
JQ505_RS22665	COG1942	4-Oxalocrotonate Tautomerase
JQ505_RS22675	COG3971	2-oxopent-4-enoate hydratase activity
JQ505_RS22680	COG1414	Transcriptional regulator
JQ505_RS22695	COG0477	Major facilitator Superfamily
JQ505_RS22710	COG1070	Carbohydrate kinase
JQ505_RS22720	COG0246	Mannitol dehydrogenase
JQ505_RS22725	COG1063	alcohol dehydrogenase
JQ505_RS22740	COG1175	transmembrane transport
JQ505_RS22745	COG0395	ABC-type sugar transport system, permease component
JQ505_RS22750	COG3842	ATPase activity
JQ505_RS22755	COG1793	dna ligase
JQ505_RS22770	COG1396	sequence-specific DNA binding
JQ505_RS22780	COG1028	Short-chain dehydrogenase reductase Sdr
JQ505_RS22785	COG0740	serine-type endopeptidase activity
JQ505_RS22790	COG0740	serine-type endopeptidase activity
JQ505_RS22795	COG0390	transport system, permease component
JQ505_RS22805	COG2072	flavoprotein involved in K transport
JQ505_RS22810	COG3654	unkown
JQ505_RS22820	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JQ505_RS22825	COG1074	ATP-dependent DNA helicase activity
JQ505_RS22830	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
JQ505_RS22840	COG0640	Transcriptional regulator
JQ505_RS22860	COG0277	FAD linked oxidase domain protein
JQ505_RS22895	COG0012	GTP binding
JQ505_RS22900	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JQ505_RS22915	COG0419	ATPase involved in DNA repair
JQ505_RS22925	COG1322	Protein conserved in bacteria
JQ505_RS22945	COG1570	exodeoxyribonuclease VII activity
JQ505_RS22950	COG1722	exodeoxyribonuclease VII activity
JQ505_RS22975	COG0318	PFAM AMP-dependent synthetase and ligase
JQ505_RS22980	COG0477	Major facilitator Superfamily
JQ505_RS23015	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
JQ505_RS23025	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
JQ505_RS23030	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JQ505_RS23045	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JQ505_RS23055	COG0668	transmembrane transport
JQ505_RS23060	COG1331	Highly conserved protein containing a thioredoxin domain
JQ505_RS23070	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JQ505_RS23080	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JQ505_RS23085	COG0791	NLP P60 protein
JQ505_RS23100	COG2755	lipolytic protein G-D-S-L family
JQ505_RS23105	COG0670	Belongs to the BI1 family
JQ505_RS23110	COG2813	Specifically methylates the guanine in position
JQ505_RS23205	COG0148	phosphopyruvate hydratase activity
JQ505_RS23215	COG0672	)-iron permease
JQ505_RS23225	COG2837	iron assimilation
JQ505_RS23265	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JQ505_RS23290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JQ505_RS23300	COG0438	transferase activity, transferring glycosyl groups
JQ505_RS23335	COG0438	transferase activity, transferring glycosyl groups
JQ505_RS23375	COG1216	Glycosyl transferase, family 2
JQ505_RS23380	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
JQ505_RS23385	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JQ505_RS23395	COG0297	glycogen (starch) synthase activity
JQ505_RS23410	COG1215	transferase activity, transferring glycosyl groups
JQ505_RS23415	COG3956	TIGRFAM MazG family protein
JQ505_RS23440	COG1309	transcriptional regulator
JQ505_RS23475	COG2226	methyltransferase
JQ505_RS23480	COG0477	Major facilitator Superfamily
JQ505_RS23485	COG2814	Major facilitator Superfamily
JQ505_RS23490	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
JQ505_RS23495	COG0121	glutamine amidotransferase
JQ505_RS23500	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JQ505_RS23505	COG3572	ergothioneine biosynthetic process
JQ505_RS23515	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JQ505_RS23520	COG1053	succinate dehydrogenase
JQ505_RS23520	COG3976	FMN-binding domain protein
JQ505_RS23530	COG0193	aminoacyl-tRNA hydrolase activity
JQ505_RS23535	COG0318	PFAM AMP-dependent synthetase and ligase
JQ505_RS23540	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
JQ505_RS23575	COG1024	Enoyl-CoA hydratase
JQ505_RS23580	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS23595	COG0488	(ABC) transporter
JQ505_RS23600	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JQ505_RS23610	COG1278	Cold shock
JQ505_RS23615	COG1278	Cold shock
JQ505_RS23620	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JQ505_RS23625	COG3583	domain protein
JQ505_RS23630	COG3583	domain protein
JQ505_RS23635	COG0765	amino acid transport
JQ505_RS23640	COG1126	abc transporter atp-binding protein
JQ505_RS23645	COG2259	Doxx family
JQ505_RS23650	COG0346	lactoylglutathione lyase activity
JQ505_RS23665	COG0084	hydrolase, TatD family'
JQ505_RS23685	COG1595	DNA-templated transcription, initiation
JQ505_RS23695	COG2319	Wd-40 repeat
JQ505_RS23695	COG4249	Peptidase C14 caspase catalytic subunit p20
JQ505_RS23700	COG1115	amino acid carrier protein
JQ505_RS23720	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JQ505_RS23725	COG1725	Transcriptional regulator
JQ505_RS23730	COG1970	mechanosensitive ion channel activity
JQ505_RS23745	COG4044	May play a role in the intracellular transport of hydrophobic ligands
JQ505_RS23750	COG2197	response regulator
JQ505_RS23765	COG1136	(ABC) transporter
JQ505_RS23790	COG2226	methyltransferase
JQ505_RS23800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JQ505_RS23810	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JQ505_RS23815	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JQ505_RS23830	COG1970	mechanosensitive ion channel activity
JQ505_RS23845	COG0521	Mo-molybdopterin cofactor biosynthetic process
JQ505_RS23845	COG0315	cyclic pyranopterin monophosphate synthase activity
JQ505_RS23850	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JQ505_RS23880	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JQ505_RS23885	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JQ505_RS23890	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JQ505_RS23895	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JQ505_RS23910	COG3639	organic phosphonate transmembrane transporter activity
JQ505_RS23915	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
JQ505_RS23920	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
JQ505_RS23935	COG2188	Transcriptional regulator
JQ505_RS23945	COG0679	Auxin Efflux Carrier
JQ505_RS23965	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
JQ505_RS24005	COG1739	Uncharacterized protein family UPF0029
JQ505_RS24015	COG0045	succinate-CoA ligase (ADP-forming) activity
JQ505_RS24025	COG0739	heme binding
JQ505_RS24045	COG0166	Belongs to the GPI family
JQ505_RS24055	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS24060	COG1309	transcriptional regulator
JQ505_RS24070	COG2272	Belongs to the type-B carboxylesterase lipase family
JQ505_RS24085	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JQ505_RS24090	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JQ505_RS24150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JQ505_RS24160	COG2239	Acts as a magnesium transporter
JQ505_RS24165	COG1959	2 iron, 2 sulfur cluster binding
JQ505_RS24170	COG1017	nitric oxide dioxygenase activity
JQ505_RS24170	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JQ505_RS24185	COG0739	heme binding
JQ505_RS24225	COG1937	Protein conserved in bacteria
JQ505_RS24255	COG1742	UPF0060 membrane protein
JQ505_RS24260	COG2020	methyltransferase activity
JQ505_RS24275	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JQ505_RS24285	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JQ505_RS24295	COG3279	Response regulator of the LytR AlgR family
JQ505_RS24300	COG3275	phosphorelay sensor kinase activity
JQ505_RS24315	COG1966	Carbon starvation protein
JQ505_RS24320	COG0025	NhaP-type Na H and K H
JQ505_RS24325	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS24330	COG2814	Major facilitator Superfamily
JQ505_RS24335	COG1250	3-hydroxyacyl-CoA dehydrogenase
JQ505_RS24345	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JQ505_RS24350	COG1028	Short-chain dehydrogenase reductase Sdr
JQ505_RS24360	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS24375	COG1024	Enoyl-CoA hydratase
JQ505_RS24405	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JQ505_RS24415	COG0583	DNA-binding transcription factor activity
JQ505_RS24450	COG2072	flavoprotein involved in K transport
JQ505_RS24455	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JQ505_RS24465	COG0656	L-ascorbic acid biosynthetic process
JQ505_RS24470	COG0488	(ABC) transporter
JQ505_RS24490	COG4152	abc transporter atp-binding protein
JQ505_RS24495	COG1668	transmembrane transport
JQ505_RS24515	COG1295	ribonuclease BN
JQ505_RS24530	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
JQ505_RS24550	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS24555	COG1309	transcriptional regulator
JQ505_RS24565	COG2205	protein histidine kinase activity
JQ505_RS24575	COG0545	Peptidyl-prolyl cis-trans isomerase
JQ505_RS24585	COG2017	converts alpha-aldose to the beta-anomer
JQ505_RS24595	COG0583	DNA-binding transcription factor activity
JQ505_RS24610	COG0477	Major facilitator Superfamily
JQ505_RS24615	COG0259	pyridoxamine-phosphate oxidase activity
JQ505_RS24650	COG1846	Transcriptional regulator
JQ505_RS24655	COG2252	PERMEase
JQ505_RS24665	COG0671	phosphoesterase, PA-phosphatase related
JQ505_RS24685	COG2814	Major facilitator Superfamily
JQ505_RS24695	COG1278	Cold shock
JQ505_RS24710	COG1652	LysM domain
JQ505_RS24730	COG4565	transcriptional regulatory protein
JQ505_RS24735	COG3290	protein histidine kinase activity
JQ505_RS24740	COG2851	Citrate transporter
JQ505_RS24770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JQ505_RS24790	COG1595	DNA-templated transcription, initiation
JQ505_RS24825	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
JQ505_RS24830	COG5285	phytanoyl-CoA dioxygenase
JQ505_RS24835	COG1216	Glycosyl transferase, family 2
JQ505_RS24840	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JQ505_RS24845	COG0366	Alpha amylase catalytic
JQ505_RS24860	COG0492	ferredoxin-NADP+ reductase activity
JQ505_RS24865	COG1755	Isoprenylcysteine carboxyl methyltransferase
JQ505_RS24880	COG0542	response to heat
JQ505_RS24885	COG1846	Transcriptional regulator
JQ505_RS24890	COG1764	response to oxidative stress
JQ505_RS24910	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JQ505_RS24915	COG0569	domain protein
JQ505_RS24935	COG1953	Uracil, thiamine, allantoin
JQ505_RS24950	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
JQ505_RS24970	COG0564	pseudouridine synthase activity
JQ505_RS25000	COG0589	response to stress
JQ505_RS25030	COG0733	neurotransmitter:sodium symporter activity
JQ505_RS25045	COG1309	transcriptional regulator
JQ505_RS25055	COG3976	FMN-binding domain protein
JQ505_RS25055	COG1053	succinate dehydrogenase
JQ505_RS25085	COG4221	oxidoreductase activity
JQ505_RS25100	COG2124	cytochrome p450
JQ505_RS25115	COG1024	Enoyl-CoA hydratase
JQ505_RS25125	COG2814	Major facilitator Superfamily
JQ505_RS25135	COG1028	Short-chain dehydrogenase reductase Sdr
JQ505_RS25160	COG0454	-acetyltransferase
JQ505_RS25160	COG0456	acetyltransferase
JQ505_RS25165	COG4638	Rieske (2fe-2S)
JQ505_RS25170	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS25175	COG2124	cytochrome p450
JQ505_RS25190	COG1028	Short-chain dehydrogenase reductase Sdr
JQ505_RS25235	COG1028	Short-chain dehydrogenase reductase Sdr
JQ505_RS25255	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JQ505_RS25285	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JQ505_RS25300	COG0243	molybdopterin cofactor binding
JQ505_RS25305	COG0477	Major facilitator Superfamily
JQ505_RS25310	COG1028	Short-chain dehydrogenase reductase Sdr
JQ505_RS25320	COG0493	'glutamate synthase
JQ505_RS25320	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
JQ505_RS25330	COG3383	formate dehydrogenase (NAD+) activity
JQ505_RS25340	COG2814	Major facilitator Superfamily
JQ505_RS25350	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JQ505_RS25360	COG1024	Enoyl-CoA hydratase
JQ505_RS25410	COG2226	methyltransferase
JQ505_RS25415	COG0438	transferase activity, transferring glycosyl groups
JQ505_RS25425	COG0318	PFAM AMP-dependent synthetase and ligase
JQ505_RS25495	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JQ505_RS25500	COG0581	inorganic phosphate transmembrane transporter activity
JQ505_RS25520	COG0745	RESPONSE REGULATOR receiver
JQ505_RS25540	COG2897	thiosulfate sulfurtransferase activity
JQ505_RS25555	COG4044	May play a role in the intracellular transport of hydrophobic ligands
JQ505_RS25560	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JQ505_RS25565	COG4988	ABC transporter
JQ505_RS25570	COG1294	oxidase, subunit
JQ505_RS25575	COG1271	oxidase subunit
JQ505_RS25605	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JQ505_RS25630	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JQ505_RS25640	COG1362	aminopeptidase activity
JQ505_RS25655	COG2217	Heavy metal translocating P-type atpase
JQ505_RS25675	COG0745	RESPONSE REGULATOR receiver
JQ505_RS25680	COG2205	protein histidine kinase activity
JQ505_RS25685	COG0047	phosphoribosylformylglycinamidine synthase activity
JQ505_RS25690	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JQ505_RS25745	COG0778	Nitroreductase
JQ505_RS25750	COG0386	Belongs to the glutathione peroxidase family
JQ505_RS25770	COG2132	Multicopper oxidase
JQ505_RS25785	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JQ505_RS25830	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
JQ505_RS25835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JQ505_RS25855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JQ505_RS25865	COG2197	response regulator
JQ505_RS25875	COG0697	spore germination
JQ505_RS25910	COG1902	pentaerythritol trinitrate reductase activity
JQ505_RS25920	COG3634	alkyl hydroperoxide reductase activity
JQ505_RS25925	COG0583	DNA-binding transcription factor activity
JQ505_RS25940	COG1301	dicarboxylic acid transport
JQ505_RS25945	COG3290	protein histidine kinase activity
JQ505_RS25950	COG4565	transcriptional regulatory protein
JQ505_RS25960	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JQ505_RS25965	COG0477	Major facilitator Superfamily
JQ505_RS25970	COG2375	cellular response to nickel ion
JQ505_RS25975	COG2357	RelA SpoT domain protein
JQ505_RS25990	COG0640	Transcriptional regulator
JQ505_RS26000	COG2226	methyltransferase
JQ505_RS26010	COG3433	isochorismatase activity
JQ505_RS26010	COG1535	isochorismatase
JQ505_RS26035	COG0477	Major facilitator Superfamily
JQ505_RS26040	COG2197	response regulator
JQ505_RS26045	COG0318	PFAM AMP-dependent synthetase and ligase
JQ505_RS26050	COG1024	Enoyl-CoA hydratase
JQ505_RS26055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JQ505_RS26070	COG1522	sequence-specific DNA binding
JQ505_RS26075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JQ505_RS26085	COG1028	Short-chain dehydrogenase reductase Sdr
JQ505_RS26090	COG1021	2,3-dihydroxybenzoate-AMP ligase
JQ505_RS26095	COG3433	isochorismatase activity
JQ505_RS26095	COG1535	isochorismatase
JQ505_RS26100	COG1132	(ABC) transporter
JQ505_RS26125	COG0589	response to stress
JQ505_RS26145	COG3290	protein histidine kinase activity
JQ505_RS26155	COG0438	transferase activity, transferring glycosyl groups
JQ505_RS26165	COG2072	flavoprotein involved in K transport
JQ505_RS26175	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JQ505_RS26195	COG1846	Transcriptional regulator
JQ505_RS26200	COG0477	Major facilitator Superfamily
JQ505_RS26230	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JQ505_RS26240	COG0436	Aminotransferase
JQ505_RS26265	COG2205	protein histidine kinase activity
JQ505_RS26270	COG0745	RESPONSE REGULATOR receiver
JQ505_RS26305	COG0515	serine threonine protein kinase
JQ505_RS26335	COG1309	transcriptional regulator
JQ505_RS26345	COG1024	Enoyl-CoA hydratase
JQ505_RS26350	COG0183	Belongs to the thiolase family
JQ505_RS26355	COG0318	PFAM AMP-dependent synthetase and ligase
JQ505_RS26365	COG0183	Belongs to the thiolase family
JQ505_RS26370	COG2030	dehydratase
JQ505_RS26370	COG1012	belongs to the aldehyde dehydrogenase family
JQ505_RS26395	COG0318	PFAM AMP-dependent synthetase and ligase
JQ505_RS26400	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JQ505_RS26415	COG1028	Short-chain dehydrogenase reductase Sdr
JQ505_RS26460	COG1028	Short-chain dehydrogenase reductase Sdr
JQ505_RS26485	COG1028	Short-chain dehydrogenase reductase Sdr
JQ505_RS26510	COG4941	Belongs to the sigma-70 factor family
JQ505_RS26515	COG3795	YCII-related domain
JQ505_RS26840	COG0582	viral genome integration into host DNA
JQ505_RS26870	COG2130	NADP-dependent
JQ505_RS26895	COG1946	Acyl-CoA thioesterase
JQ505_RS26900	COG0318	PFAM AMP-dependent synthetase and ligase
JQ505_RS26905	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS26910	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS26945	COG0183	Belongs to the thiolase family
JQ505_RS26950	COG2188	Transcriptional regulator
JQ505_RS26955	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JQ505_RS26965	COG3718	enzyme involved in inositol metabolism
JQ505_RS26970	COG3962	Belongs to the TPP enzyme family
JQ505_RS26980	COG0673	inositol 2-dehydrogenase activity
JQ505_RS26985	COG1082	Xylose isomerase domain protein TIM barrel
JQ505_RS26995	COG3958	Transketolase
JQ505_RS27000	COG3959	Transketolase, thiamine diphosphate binding domain
JQ505_RS27005	COG0477	Major facilitator Superfamily
JQ505_RS27015	COG1028	Short-chain dehydrogenase reductase Sdr
JQ505_RS27030	COG1132	(ABC) transporter
JQ505_RS27045	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
JQ505_RS27050	COG0784	Response regulator, receiver
JQ505_RS27070	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JQ505_RS27095	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JQ505_RS27105	COG1028	Short-chain dehydrogenase reductase Sdr
JQ505_RS27115	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS27120	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS27125	COG0318	PFAM AMP-dependent synthetase and ligase
JQ505_RS27135	COG0789	Transcriptional regulator
JQ505_RS27145	COG2070	2-Nitropropane dioxygenase
JQ505_RS27165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JQ505_RS27200	COG2814	Major facilitator Superfamily
JQ505_RS27205	COG1053	succinate dehydrogenase
JQ505_RS27210	COG2124	cytochrome p450
JQ505_RS27215	COG0183	Belongs to the thiolase family
JQ505_RS27225	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JQ505_RS27230	COG1028	Short-chain dehydrogenase reductase Sdr
JQ505_RS27235	COG1024	Enoyl-CoA hydratase
JQ505_RS27255	COG0702	epimerase
JQ505_RS27260	COG0657	acetylesterase activity
JQ505_RS27265	COG2072	flavoprotein involved in K transport
JQ505_RS27295	COG0183	Belongs to the thiolase family
JQ505_RS27300	COG1309	transcriptional regulator
JQ505_RS27310	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS27315	COG0318	PFAM AMP-dependent synthetase and ligase
JQ505_RS27320	COG1024	Enoyl-CoA hydratase
JQ505_RS27325	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS27330	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS27335	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS27340	COG0656	L-ascorbic acid biosynthetic process
JQ505_RS27360	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JQ505_RS27365	COG0346	lactoylglutathione lyase activity
JQ505_RS27370	COG2267	carboxylic ester hydrolase activity
JQ505_RS27375	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS27410	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
JQ505_RS27420	COG4585	Histidine kinase
JQ505_RS27425	COG2197	response regulator
JQ505_RS27430	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JQ505_RS27445	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JQ505_RS27450	COG4569	acetaldehyde dehydrogenase (acetylating) activity
JQ505_RS27455	COG3971	2-oxopent-4-enoate hydratase activity
JQ505_RS27460	COG1053	succinate dehydrogenase
JQ505_RS27465	COG2030	dehydratase
JQ505_RS27490	COG1414	Transcriptional regulator
JQ505_RS27495	COG0477	Major facilitator Superfamily
JQ505_RS27500	COG3285	dna ligase
JQ505_RS27500	COG1793	dna ligase
JQ505_RS27540	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
JQ505_RS27540	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JQ505_RS27570	COG0471	metal ion transport
JQ505_RS27590	COG1028	Short-chain dehydrogenase reductase Sdr
JQ505_RS27610	COG2030	dehydratase
JQ505_RS27615	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS27620	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS27625	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS27630	COG1309	transcriptional regulator
JQ505_RS27635	COG3387	PFAM Glycoside hydrolase 15-related
JQ505_RS27640	COG1609	Transcriptional regulator
JQ505_RS27645	COG0803	Belongs to the bacterial solute-binding protein 9 family
JQ505_RS27650	COG1121	(ABC) transporter
JQ505_RS27655	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JQ505_RS27675	COG1984	allophanate hydrolase subunit 2
JQ505_RS27685	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JQ505_RS27690	COG0215	cysteine-tRNA ligase activity
JQ505_RS27695	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
JQ505_RS27700	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JQ505_RS27705	COG1329	Transcriptional regulator
JQ505_RS27715	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JQ505_RS27720	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JQ505_RS27730	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
JQ505_RS27740	COG0288	reversible hydration of carbon dioxide
JQ505_RS27760	COG4762	Protein conserved in bacteria
JQ505_RS27780	COG1960	acyl-CoA dehydrogenase activity
JQ505_RS27805	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JQ505_RS27815	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JQ505_RS27825	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
JQ505_RS27830	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
JQ505_RS27835	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JQ505_RS27860	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JQ505_RS27865	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JQ505_RS27870	COG0302	gtp cyclohydrolase
JQ505_RS27875	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JQ505_RS27880	COG2815	serine threonine protein kinase
JQ505_RS27880	COG0515	serine threonine protein kinase
JQ505_RS27890	COG0037	tRNA processing
JQ505_RS27900	COG2027	D-alanyl-D-alanine carboxypeptidase
JQ505_RS27925	COG0442	prolyl-tRNA aminoacylation
JQ505_RS27930	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JQ505_RS27970	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
JQ505_RS27975	COG3639	organic phosphonate transmembrane transporter activity
JQ505_RS28045	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
JQ505_RS28150	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
JQ505_RS28265	COG4585	Histidine kinase
JQ505_RS28270	COG2197	response regulator
JQ505_RS28325	COG1024	Enoyl-CoA hydratase
JQ505_RS28330	COG3835	regulator
JQ505_RS28335	COG0477	Major facilitator Superfamily
JQ505_RS28370	COG1028	Short-chain dehydrogenase reductase Sdr
JQ505_RS28390	COG2124	cytochrome p450
JQ505_RS28400	COG1028	Short-chain dehydrogenase reductase Sdr
JQ505_RS28405	COG0183	Belongs to the thiolase family
JQ505_RS28420	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JQ505_RS28440	COG2801	Transposase and inactivated derivatives
JQ505_RS28445	COG4974	Belongs to the 'phage' integrase family
JQ505_RS28530	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JQ505_RS28585	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JQ505_RS28590	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
JQ505_RS28600	COG0739	heme binding