locus-tag	class	description
PD630_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PD630_RS00010	COG0592	DNA-directed DNA polymerase activity
PD630_RS00015	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
PD630_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PD630_RS00025	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
PD630_RS00045	COG0187	DNA topoisomerase II activity
PD630_RS00055	COG2018	Roadblock/LC7 domain
PD630_RS00075	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PD630_RS00125	COG0705	Rhomboid family
PD630_RS00125	COG0457	Tetratricopeptide repeat
PD630_RS00150	COG0515	serine threonine protein kinase
PD630_RS00150	COG2815	serine threonine protein kinase
PD630_RS00155	COG0515	serine threonine protein kinase
PD630_RS00160	COG0768	penicillin binding
PD630_RS00175	COG1716	ATPase activity
PD630_RS00180	COG1716	ATPase activity
PD630_RS00255	COG0069	glutamate synthase activity
PD630_RS00255	COG0067	glutamate synthase
PD630_RS00255	COG0070	glutamate synthase
PD630_RS00265	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
PD630_RS00270	COG0824	Thioesterase
PD630_RS00285	COG0300	oxidoreductase activity
PD630_RS00300	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
PD630_RS00340	COG2501	S4 domain
PD630_RS00355	COG0531	amino acid
PD630_RS00360	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PD630_RS00390	COG4770	biotin carboxylase activity
PD630_RS00400	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PD630_RS00410	COG0789	Transcriptional regulator
PD630_RS00415	COG1022	Amp-dependent synthetase and ligase
PD630_RS00460	COG1597	lipid kinase activity
PD630_RS00475	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
PD630_RS00525	COG0318	PFAM AMP-dependent synthetase and ligase
PD630_RS00545	COG2814	Major facilitator Superfamily
PD630_RS00550	COG3246	L-lysine catabolic process to acetate
PD630_RS00555	COG2175	clavaminate synthase activity
PD630_RS00585	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PD630_RS00590	COG4948	Mandelate Racemase Muconate Lactonizing
PD630_RS00595	COG0583	DNA-binding transcription factor activity
PD630_RS00615	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PD630_RS00620	COG0066	3-isopropylmalate dehydratase activity
PD630_RS00625	COG0473	3-isopropylmalate dehydrogenase activity
PD630_RS00625	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PD630_RS00690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PD630_RS00710	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PD630_RS00715	COG0179	Fumarylacetoacetate (FAA) hydrolase
PD630_RS00730	COG2814	Major facilitator Superfamily
PD630_RS00740	COG1414	Transcriptional regulator
PD630_RS00775	COG0402	S-adenosylhomocysteine deaminase activity
PD630_RS00790	COG2226	methyltransferase
PD630_RS00800	COG1309	transcriptional regulator
PD630_RS00805	COG0318	PFAM AMP-dependent synthetase and ligase
PD630_RS00850	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PD630_RS00870	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PD630_RS00875	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
PD630_RS00885	COG0477	Major facilitator Superfamily
PD630_RS00885	COG2814	Major facilitator Superfamily
PD630_RS00890	COG2814	Major facilitator Superfamily
PD630_RS00910	COG4941	Belongs to the sigma-70 factor family
PD630_RS00915	COG3795	YCII-related domain
PD630_RS00925	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS00930	COG0477	Major facilitator Superfamily
PD630_RS00935	COG3959	Transketolase, thiamine diphosphate binding domain
PD630_RS00940	COG3958	Transketolase
PD630_RS00955	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
PD630_RS00960	COG1609	Transcriptional regulator
PD630_RS00970	COG2814	Major facilitator Superfamily
PD630_RS00995	COG2159	amidohydrolase
PD630_RS01030	COG3842	ATPase activity
PD630_RS01050	COG2368	4-hydroxyphenylacetate
PD630_RS01070	COG1574	metal-dependent hydrolase with the TIM-barrel fold
PD630_RS01080	COG0833	amino acid
PD630_RS01105	COG1760	l-serine dehydratase
PD630_RS01130	COG1072	(Pantothenic acid kinase))
PD630_RS01145	COG0589	response to stress
PD630_RS01150	COG2814	Major facilitator Superfamily
PD630_RS01165	COG0183	Belongs to the thiolase family
PD630_RS01190	COG2353	YceI-like domain
PD630_RS01195	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PD630_RS01200	COG1846	Transcriptional regulator
PD630_RS01215	COG3250	beta-galactosidase activity
PD630_RS01230	COG0657	acetylesterase activity
PD630_RS01245	COG2814	Major facilitator Superfamily
PD630_RS01250	COG0179	Fumarylacetoacetate (FAA) hydrolase
PD630_RS01295	COG5002	protein histidine kinase activity
PD630_RS01295	COG3447	MASE1 domain protein
PD630_RS01295	COG5001	Diguanylate cyclase
PD630_RS01335	COG0589	response to stress
PD630_RS01340	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PD630_RS01345	COG0747	negative chemotaxis
PD630_RS01355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PD630_RS01360	COG0444	Belongs to the ABC transporter superfamily
PD630_RS01365	COG4608	Belongs to the ABC transporter superfamily
PD630_RS01375	COG4948	Mandelate Racemase Muconate Lactonizing
PD630_RS01380	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PD630_RS01410	COG3547	Transposase (IS116 IS110 IS902 family)
PD630_RS01445	COG2610	gluconate transmembrane transporter activity
PD630_RS01450	COG2828	Protein conserved in bacteria
PD630_RS01465	COG2329	Antibiotic biosynthesis monooxygenase
PD630_RS01475	COG1012	belongs to the aldehyde dehydrogenase family
PD630_RS01480	COG0473	3-isopropylmalate dehydrogenase activity
PD630_RS01485	COG3493	citrate carrier protein
PD630_RS01510	COG3842	ATPase activity
PD630_RS01570	COG1024	Enoyl-CoA hydratase
PD630_RS01575	COG0604	alcohol dehydrogenase
PD630_RS01575	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS01575	COG3321	synthase
PD630_RS01585	COG0183	Belongs to the thiolase family
PD630_RS01595	COG1309	transcriptional regulator
PD630_RS01615	COG1024	Enoyl-CoA hydratase
PD630_RS01635	COG2814	Major facilitator Superfamily
PD630_RS01645	COG0477	Major facilitator Superfamily
PD630_RS01655	COG1960	acyl-CoA dehydrogenase activity
PD630_RS01660	COG0318	PFAM AMP-dependent synthetase and ligase
PD630_RS01665	COG0477	Major facilitator Superfamily
PD630_RS01670	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PD630_RS01675	COG2197	response regulator
PD630_RS01690	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PD630_RS01695	COG0477	Major facilitator Superfamily
PD630_RS01695	COG2814	Major facilitator Superfamily
PD630_RS01700	COG1012	belongs to the aldehyde dehydrogenase family
PD630_RS01720	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS01730	COG3962	Belongs to the TPP enzyme family
PD630_RS01770	COG1846	Transcriptional regulator
PD630_RS01780	COG1573	uracil-dna glycosylase
PD630_RS01785	COG2130	NADP-dependent
PD630_RS01825	COG2226	methyltransferase
PD630_RS01855	COG2119	membrane
PD630_RS01885	COG0154	amidase activity
PD630_RS01900	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PD630_RS01935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PD630_RS01965	COG1528	Iron-storage protein
PD630_RS01975	COG1528	Iron-storage protein
PD630_RS01980	COG1316	TRANSCRIPTIONal
PD630_RS02010	COG0406	alpha-ribazole phosphatase activity
PD630_RS02050	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PD630_RS02070	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
PD630_RS02070	COG2146	nitrite reductase [NAD(P)H] activity
PD630_RS02080	COG0204	Acyl-transferase
PD630_RS02090	COG0561	phosphatase activity
PD630_RS02100	COG2385	sporulation resulting in formation of a cellular spore
PD630_RS02105	COG0438	transferase activity, transferring glycosyl groups
PD630_RS02115	COG1216	Glycosyl transferase, family 2
PD630_RS02120	COG0671	phosphoesterase, PA-phosphatase related
PD630_RS02125	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
PD630_RS02130	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PD630_RS02145	COG5479	isomerase activity
PD630_RS02145	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
PD630_RS02155	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
PD630_RS02170	COG0318	PFAM AMP-dependent synthetase and ligase
PD630_RS02175	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PD630_RS02175	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
PD630_RS02175	COG3321	synthase
PD630_RS02180	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PD630_RS02230	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS02235	COG0277	FAD linked oxidase domain protein
PD630_RS02255	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PD630_RS02265	COG1609	Transcriptional regulator
PD630_RS02270	COG1129	ABC transporter
PD630_RS02275	COG1172	Belongs to the binding-protein-dependent transport system permease family
PD630_RS02280	COG1172	Belongs to the binding-protein-dependent transport system permease family
PD630_RS02290	COG3254	rhamnose metabolic process
PD630_RS02305	COG3347	Dehydrogenase
PD630_RS02305	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS02310	COG1070	Carbohydrate kinase
PD630_RS02325	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
PD630_RS02330	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PD630_RS02335	COG1088	dTDP-glucose 4,6-dehydratase activity
PD630_RS02355	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
PD630_RS02385	COG1215	transferase activity, transferring glycosyl groups
PD630_RS02405	COG1162	GTPase activity
PD630_RS02410	COG1216	Glycosyl transferase, family 2
PD630_RS02435	COG1063	alcohol dehydrogenase
PD630_RS02465	COG0640	Transcriptional regulator
PD630_RS02480	COG4085	toxin activity
PD630_RS02480	COG0737	Belongs to the 5'-nucleotidase family
PD630_RS02480	COG1525	nuclease
PD630_RS02485	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PD630_RS02510	COG0640	Transcriptional regulator
PD630_RS02525	COG0583	DNA-binding transcription factor activity
PD630_RS02530	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS02540	COG0477	Major facilitator Superfamily
PD630_RS02545	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PD630_RS02555	COG0477	Major facilitator Superfamily
PD630_RS02590	COG0270	DNA (cytosine-5-)-methyltransferase activity
PD630_RS02595	COG0025	NhaP-type Na H and K H
PD630_RS02610	COG0287	Prephenate dehydrogenase
PD630_RS02620	COG0590	tRNA wobble adenosine to inosine editing
PD630_RS02635	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS02660	COG1414	Transcriptional regulator
PD630_RS02690	COG2409	Drug exporters of the RND superfamily
PD630_RS02710	COG3119	arylsulfatase activity
PD630_RS02715	COG0343	queuine tRNA-ribosyltransferase activity
PD630_RS02740	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PD630_RS02745	COG3226	Transcriptional regulator
PD630_RS02810	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PD630_RS02820	COG4592	Periplasmic binding protein
PD630_RS02855	COG2197	response regulator
PD630_RS02860	COG0154	amidase activity
PD630_RS02865	COG0183	Belongs to the thiolase family
PD630_RS02870	COG1250	3-hydroxyacyl-CoA dehydrogenase
PD630_RS02870	COG1024	Enoyl-CoA hydratase
PD630_RS02880	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PD630_RS02900	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PD630_RS02905	COG1309	transcriptional regulator
PD630_RS02910	COG2814	Major facilitator Superfamily
PD630_RS02945	COG0583	DNA-binding transcription factor activity
PD630_RS02955	COG0439	Biotin carboxylase
PD630_RS02960	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PD630_RS02965	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PD630_RS02990	COG0604	alcohol dehydrogenase
PD630_RS02990	COG3321	synthase
PD630_RS02995	COG2890	protein-(glutamine-N5) methyltransferase activity
PD630_RS03010	COG1289	transmembrane transporter activity
PD630_RS03015	COG0405	Gamma-glutamyltransferase
PD630_RS03020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PD630_RS03030	COG1473	amidohydrolase
PD630_RS03030	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
PD630_RS03050	COG0463	Glycosyl transferase, family 2
PD630_RS03070	COG4941	Belongs to the sigma-70 factor family
PD630_RS03090	COG1960	acyl-CoA dehydrogenase activity
PD630_RS03100	COG1024	Enoyl-CoA hydratase
PD630_RS03145	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
PD630_RS03150	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
PD630_RS03210	COG0366	Alpha amylase catalytic
PD630_RS03215	COG1609	Transcriptional regulator
PD630_RS03220	COG3842	ATPase activity
PD630_RS03235	COG2175	clavaminate synthase activity
PD630_RS03255	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PD630_RS03265	COG1024	Enoyl-CoA hydratase
PD630_RS03270	COG0583	DNA-binding transcription factor activity
PD630_RS03275	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS03295	COG0183	Belongs to the thiolase family
PD630_RS03300	COG1960	acyl-CoA dehydrogenase activity
PD630_RS03305	COG1960	acyl-CoA dehydrogenase activity
PD630_RS03330	COG1174	glycine betaine transport
PD630_RS03345	COG1940	carbohydrate kinase activity
PD630_RS03365	COG2197	response regulator
PD630_RS03375	COG3119	arylsulfatase activity
PD630_RS03385	COG1309	transcriptional regulator
PD630_RS03390	COG0183	Belongs to the thiolase family
PD630_RS03405	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS03410	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PD630_RS03415	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS03425	COG0183	Belongs to the thiolase family
PD630_RS03435	COG0318	PFAM AMP-dependent synthetase and ligase
PD630_RS03440	COG1024	Enoyl-CoA hydratase
PD630_RS03450	COG0318	PFAM AMP-dependent synthetase and ligase
PD630_RS03455	COG1960	acyl-CoA dehydrogenase activity
PD630_RS03465	COG2015	COG2015, Alkyl sulfatase and related hydrolases
PD630_RS03470	COG0628	permease
PD630_RS03520	COG0659	secondary active sulfate transmembrane transporter activity
PD630_RS03535	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PD630_RS03540	COG2132	Multicopper oxidase
PD630_RS03570	COG0640	Transcriptional regulator
PD630_RS03590	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PD630_RS03600	COG1408	metallophosphoesterase
PD630_RS03635	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PD630_RS03660	COG0494	nUDIX hydrolase
PD630_RS03670	COG0596	Alpha beta hydrolase
PD630_RS03680	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PD630_RS03685	COG0477	Major facilitator Superfamily
PD630_RS03695	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PD630_RS03700	COG0747	negative chemotaxis
PD630_RS03705	COG0601	transmembrane transport
PD630_RS03710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PD630_RS03765	COG0477	Major facilitator Superfamily
PD630_RS03770	COG0583	DNA-binding transcription factor activity
PD630_RS03775	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PD630_RS03780	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
PD630_RS03785	COG1205	dead DEAH box helicase
PD630_RS03785	COG1111	helicase
PD630_RS03790	COG1278	Cold shock
PD630_RS03800	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PD630_RS03800	COG1754	DNA topoisomerase type I activity
PD630_RS03855	COG0765	amino acid transport
PD630_RS03860	COG0765	amino acid transport
PD630_RS03865	COG1126	abc transporter atp-binding protein
PD630_RS03880	COG3069	C4-dicarboxylate transmembrane transporter activity
PD630_RS03890	COG2508	Transcriptional regulator
PD630_RS03915	COG1012	belongs to the aldehyde dehydrogenase family
PD630_RS03960	COG4941	Belongs to the sigma-70 factor family
PD630_RS03965	COG2957	Belongs to the agmatine deiminase family
PD630_RS03970	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PD630_RS03975	COG1309	transcriptional regulator
PD630_RS04000	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PD630_RS04005	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PD630_RS04015	COG1309	transcriptional regulator
PD630_RS04025	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PD630_RS04030	COG1024	Enoyl-CoA hydratase
PD630_RS04035	COG0477	Major facilitator Superfamily
PD630_RS04045	COG2027	D-alanyl-D-alanine carboxypeptidase
PD630_RS04055	COG0037	tRNA processing
PD630_RS04065	COG2815	serine threonine protein kinase
PD630_RS04065	COG0515	serine threonine protein kinase
PD630_RS04075	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PD630_RS04080	COG0302	gtp cyclohydrolase
PD630_RS04085	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PD630_RS04115	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
PD630_RS04120	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
PD630_RS04125	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
PD630_RS04140	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
PD630_RS04150	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
PD630_RS04235	COG1194	a g-specific adenine glycosylase
PD630_RS04240	COG0288	reversible hydration of carbon dioxide
PD630_RS04255	COG1113	amino acid transport
PD630_RS04265	COG2186	Transcriptional regulator
PD630_RS04270	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
PD630_RS04280	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PD630_RS04285	COG2847	Copper chaperone PCu(A)C
PD630_RS04290	COG1329	Transcriptional regulator
PD630_RS04295	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
PD630_RS04305	COG0215	cysteine-tRNA ligase activity
PD630_RS04310	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PD630_RS04320	COG1984	allophanate hydrolase subunit 2
PD630_RS04325	COG0686	Belongs to the AlaDH PNT family
PD630_RS04340	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PD630_RS04345	COG2902	Dehydrogenase
PD630_RS04355	COG1522	sequence-specific DNA binding
PD630_RS04365	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PD630_RS04380	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS04395	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
PD630_RS04425	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PD630_RS04430	COG1120	ATPase activity
PD630_RS04435	COG0803	Belongs to the bacterial solute-binding protein 9 family
PD630_RS04440	COG1609	Transcriptional regulator
PD630_RS04450	COG1309	transcriptional regulator
PD630_RS04455	COG1960	acyl-CoA dehydrogenase activity
PD630_RS04460	COG1960	acyl-CoA dehydrogenase activity
PD630_RS04465	COG1960	acyl-CoA dehydrogenase activity
PD630_RS04485	COG2072	flavoprotein involved in K transport
PD630_RS04490	COG2197	response regulator
PD630_RS04520	COG0596	Alpha beta hydrolase
PD630_RS04540	COG1529	Aldehyde oxidase and xanthine dehydrogenase
PD630_RS04540	COG2080	2 iron, 2 sulfur cluster binding
PD630_RS04560	COG2351	hydroxyisourate hydrolase activity
PD630_RS04570	COG0402	S-adenosylhomocysteine deaminase activity
PD630_RS04575	COG2267	carboxylic ester hydrolase activity
PD630_RS04585	COG2233	PERMEase
PD630_RS04600	COG1953	Uracil, thiamine, allantoin
PD630_RS04630	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
PD630_RS04645	COG0714	Associated with various cellular activities
PD630_RS04665	COG2030	dehydratase
PD630_RS04675	COG3971	2-oxopent-4-enoate hydratase activity
PD630_RS04680	COG4569	acetaldehyde dehydrogenase (acetylating) activity
PD630_RS04685	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PD630_RS04710	COG1960	acyl-CoA dehydrogenase activity
PD630_RS04715	COG2267	carboxylic ester hydrolase activity
PD630_RS04720	COG0346	lactoylglutathione lyase activity
PD630_RS04725	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PD630_RS04735	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PD630_RS04750	COG1454	alcohol dehydrogenase
PD630_RS04765	COG1609	Transcriptional regulator
PD630_RS04770	COG1252	NADH dehydrogenase
PD630_RS04780	COG0028	Belongs to the TPP enzyme family
PD630_RS04795	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PD630_RS04810	COG0738	Major facilitator superfamily
PD630_RS04820	COG0028	Belongs to the TPP enzyme family
PD630_RS04830	COG1609	Transcriptional regulator
PD630_RS04835	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PD630_RS04845	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PD630_RS04850	COG0477	Major facilitator Superfamily
PD630_RS04865	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PD630_RS04875	COG1012	belongs to the aldehyde dehydrogenase family
PD630_RS04885	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PD630_RS04910	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS04940	COG3119	arylsulfatase activity
PD630_RS04950	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PD630_RS04990	COG5285	phytanoyl-CoA dioxygenase
PD630_RS04995	COG1846	Transcriptional regulator
PD630_RS05000	COG2814	Major facilitator Superfamily
PD630_RS05015	COG2271	Major facilitator Superfamily
PD630_RS05020	COG0251	oxidation-reduction process
PD630_RS05045	COG0583	DNA-binding transcription factor activity
PD630_RS05060	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS05065	COG2124	cytochrome p450
PD630_RS05070	COG0656	L-ascorbic acid biosynthetic process
PD630_RS05075	COG0561	phosphatase activity
PD630_RS05080	COG1960	acyl-CoA dehydrogenase activity
PD630_RS05085	COG1960	acyl-CoA dehydrogenase activity
PD630_RS05090	COG1960	acyl-CoA dehydrogenase activity
PD630_RS05095	COG1024	Enoyl-CoA hydratase
PD630_RS05100	COG0318	PFAM AMP-dependent synthetase and ligase
PD630_RS05105	COG1960	acyl-CoA dehydrogenase activity
PD630_RS05115	COG1309	transcriptional regulator
PD630_RS05120	COG0183	Belongs to the thiolase family
PD630_RS05125	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PD630_RS05130	COG0375	protein maturation
PD630_RS05135	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
PD630_RS05180	COG0298	carbon dioxide binding
PD630_RS05200	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS05205	COG0477	Major facilitator Superfamily
PD630_RS05215	COG0252	asparaginase activity
PD630_RS05250	COG0667	Aldo Keto reductase
PD630_RS05255	COG4608	Belongs to the ABC transporter superfamily
PD630_RS05260	COG0444	Belongs to the ABC transporter superfamily
PD630_RS05265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PD630_RS05270	COG0601	transmembrane transport
PD630_RS05290	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
PD630_RS05295	COG1349	DNA-binding transcription factor activity
PD630_RS05310	COG0409	Hydrogenase expression formation protein
PD630_RS05315	COG0298	carbon dioxide binding
PD630_RS05325	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
PD630_RS05335	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
PD630_RS05340	COG0740	serine-type endopeptidase activity
PD630_RS05350	COG0579	oxidoreductase
PD630_RS05355	COG1309	transcriptional regulator
PD630_RS05375	COG0235	Class ii aldolase
PD630_RS05380	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PD630_RS05390	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PD630_RS05410	COG1960	acyl-CoA dehydrogenase activity
PD630_RS05420	COG1278	Cold shock
PD630_RS05425	COG0596	Alpha beta hydrolase
PD630_RS05430	COG0010	Belongs to the arginase family
PD630_RS05435	COG1228	amidohydrolase
PD630_RS05440	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
PD630_RS05445	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
PD630_RS05450	COG2902	Dehydrogenase
PD630_RS05465	COG5650	phosphatidylinositol metabolic process
PD630_RS05500	COG1024	Enoyl-CoA hydratase
PD630_RS05510	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS05520	COG0438	transferase activity, transferring glycosyl groups
PD630_RS05560	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS05580	COG2124	cytochrome p450
PD630_RS05635	COG0183	Belongs to the thiolase family
PD630_RS05640	COG2124	cytochrome p450
PD630_RS05675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PD630_RS05685	COG1024	Enoyl-CoA hydratase
PD630_RS05695	COG2070	2-Nitropropane dioxygenase
PD630_RS05700	COG0318	PFAM AMP-dependent synthetase and ligase
PD630_RS05705	COG1960	acyl-CoA dehydrogenase activity
PD630_RS05710	COG1960	acyl-CoA dehydrogenase activity
PD630_RS05720	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS05730	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PD630_RS05755	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
PD630_RS05780	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PD630_RS05785	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
PD630_RS05790	COG1132	(ABC) transporter
PD630_RS05795	COG1132	(ABC) transporter
PD630_RS05820	COG3486	L-lysine 6-monooxygenase (NADPH) activity
PD630_RS05860	COG3387	PFAM Glycoside hydrolase 15-related
PD630_RS05865	COG1595	DNA-templated transcription, initiation
PD630_RS05885	COG0789	Transcriptional regulator
PD630_RS05895	COG0789	Transcriptional regulator
PD630_RS05945	COG0745	RESPONSE REGULATOR receiver
PD630_RS05950	COG2205	protein histidine kinase activity
PD630_RS05965	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PD630_RS05980	COG1960	acyl-CoA dehydrogenase activity
PD630_RS05985	COG1024	Enoyl-CoA hydratase
PD630_RS05995	COG0183	Belongs to the thiolase family
PD630_RS06000	COG1960	acyl-CoA dehydrogenase activity
PD630_RS06010	COG1960	acyl-CoA dehydrogenase activity
PD630_RS06015	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS06020	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS06030	COG0318	PFAM AMP-dependent synthetase and ligase
PD630_RS06050	COG2130	NADP-dependent
PD630_RS06060	COG1178	ABC-type Fe3 transport system permease component
PD630_RS06065	COG3842	ATPase activity
PD630_RS06085	COG0446	pyridine nucleotide-disulphide oxidoreductase
PD630_RS06085	COG1902	pentaerythritol trinitrate reductase activity
PD630_RS06095	COG1129	ABC transporter
PD630_RS06100	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS06130	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS06145	COG0436	Aminotransferase
PD630_RS06175	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PD630_RS06195	COG1131	(ABC) transporter
PD630_RS06205	COG1021	2,3-dihydroxybenzoate-AMP ligase
PD630_RS06210	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS06230	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PD630_RS06235	COG0154	amidase activity
PD630_RS06245	COG1929	Belongs to the glycerate kinase type-1 family
PD630_RS06250	COG1301	dicarboxylic acid transport
PD630_RS06260	COG0583	DNA-binding transcription factor activity
PD630_RS06265	COG0477	Major facilitator Superfamily
PD630_RS06295	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PD630_RS06300	COG0477	Major facilitator Superfamily
PD630_RS06320	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
PD630_RS06340	COG4565	transcriptional regulatory protein
PD630_RS06345	COG3290	protein histidine kinase activity
PD630_RS06350	COG1301	dicarboxylic acid transport
PD630_RS06355	COG0386	Belongs to the glutathione peroxidase family
PD630_RS06370	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PD630_RS06375	COG0047	phosphoribosylformylglycinamidine synthase activity
PD630_RS06380	COG2890	protein-(glutamine-N5) methyltransferase activity
PD630_RS06405	COG1362	aminopeptidase activity
PD630_RS06410	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PD630_RS06430	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PD630_RS06440	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
PD630_RS06470	COG1271	oxidase subunit
PD630_RS06475	COG1294	oxidase, subunit
PD630_RS06480	COG4988	ABC transporter
PD630_RS06485	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
PD630_RS06495	COG4044	May play a role in the intracellular transport of hydrophobic ligands
PD630_RS06515	COG2897	thiosulfate sulfurtransferase activity
PD630_RS06535	COG0745	RESPONSE REGULATOR receiver
PD630_RS06540	COG0454	-acetyltransferase
PD630_RS06540	COG0456	acetyltransferase
PD630_RS06555	COG0581	inorganic phosphate transmembrane transporter activity
PD630_RS06560	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
PD630_RS06605	COG1309	transcriptional regulator
PD630_RS06650	COG1309	transcriptional regulator
PD630_RS06675	COG4221	oxidoreductase activity
PD630_RS06705	COG0564	pseudouridine synthase activity
PD630_RS06720	COG1764	response to oxidative stress
PD630_RS06725	COG1846	Transcriptional regulator
PD630_RS06735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PD630_RS06740	COG2851	Citrate transporter
PD630_RS06770	COG0179	Fumarylacetoacetate (FAA) hydrolase
PD630_RS06780	COG0402	S-adenosylhomocysteine deaminase activity
PD630_RS06805	COG1716	ATPase activity
PD630_RS06805	COG1131	(ABC) transporter
PD630_RS06805	COG0842	Transport permease protein
PD630_RS06820	COG0531	amino acid
PD630_RS06830	COG0542	response to heat
PD630_RS06840	COG1414	Transcriptional regulator
PD630_RS06845	COG1929	Belongs to the glycerate kinase type-1 family
PD630_RS06855	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PD630_RS06860	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PD630_RS06875	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PD630_RS06880	COG2197	response regulator
PD630_RS06885	COG4585	Histidine kinase
PD630_RS06895	COG1131	(ABC) transporter
PD630_RS06900	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PD630_RS06910	COG2409	Drug exporters of the RND superfamily
PD630_RS06915	COG5285	phytanoyl-CoA dioxygenase
PD630_RS06945	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PD630_RS06950	COG1595	DNA-templated transcription, initiation
PD630_RS06970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PD630_RS06975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PD630_RS06980	COG2814	Major facilitator Superfamily
PD630_RS06985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PD630_RS07010	COG1940	carbohydrate kinase activity
PD630_RS07010	COG1846	Transcriptional regulator
PD630_RS07020	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PD630_RS07025	COG1116	anion transmembrane transporter activity
PD630_RS07030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PD630_RS07035	COG1132	(ABC) transporter
PD630_RS07055	COG1652	LysM domain
PD630_RS07070	COG1278	Cold shock
PD630_RS07080	COG2814	Major facilitator Superfamily
PD630_RS07115	COG2252	PERMEase
PD630_RS07155	COG0300	oxidoreductase activity
PD630_RS07190	COG3845	ABC transporter
PD630_RS07195	COG4603	Belongs to the binding-protein-dependent transport system permease family
PD630_RS07200	COG1079	Belongs to the binding-protein-dependent transport system permease family
PD630_RS07225	COG0259	pyridoxamine-phosphate oxidase activity
PD630_RS07235	COG2017	converts alpha-aldose to the beta-anomer
PD630_RS07245	COG0545	Peptidyl-prolyl cis-trans isomerase
PD630_RS07260	COG0668	transmembrane transport
PD630_RS07265	COG0415	Belongs to the DNA photolyase family
PD630_RS07285	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
PD630_RS07300	COG0367	asparagine synthase
PD630_RS07315	COG2080	2 iron, 2 sulfur cluster binding
PD630_RS07315	COG1529	Aldehyde oxidase and xanthine dehydrogenase
PD630_RS07320	COG3224	Antibiotic biosynthesis monooxygenase
PD630_RS07330	COG2132	Multicopper oxidase
PD630_RS07335	COG1668	transmembrane transport
PD630_RS07340	COG4152	abc transporter atp-binding protein
PD630_RS07360	COG0488	(ABC) transporter
PD630_RS07365	COG2226	methyltransferase
PD630_RS07370	COG0656	L-ascorbic acid biosynthetic process
PD630_RS07390	COG2409	Drug exporters of the RND superfamily
PD630_RS07405	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PD630_RS07420	COG1024	Enoyl-CoA hydratase
PD630_RS07430	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
PD630_RS07455	COG3275	phosphorelay sensor kinase activity
PD630_RS07460	COG3279	Response regulator of the LytR AlgR family
PD630_RS07470	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PD630_RS07480	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PD630_RS07495	COG3285	dna ligase
PD630_RS07495	COG1793	dna ligase
PD630_RS07520	COG1119	ATPase activity
PD630_RS07525	COG1802	Transcriptional regulator
PD630_RS07535	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PD630_RS07540	COG1960	acyl-CoA dehydrogenase activity
PD630_RS07545	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS07560	COG0183	Belongs to the thiolase family
PD630_RS07595	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PD630_RS07600	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PD630_RS07605	COG3185	4-Hydroxyphenylpyruvate dioxygenase
PD630_RS07620	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PD630_RS07625	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PD630_RS07635	COG0659	secondary active sulfate transmembrane transporter activity
PD630_RS07645	COG0477	Major facilitator Superfamily
PD630_RS07655	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
PD630_RS07670	COG0129	dihydroxy-acid dehydratase activity
PD630_RS07680	COG0667	Aldo Keto reductase
PD630_RS07690	COG0277	FAD linked oxidase domain protein
PD630_RS07720	COG0477	Major facilitator Superfamily
PD630_RS07725	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PD630_RS07750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PD630_RS07765	COG0598	Magnesium transport protein CorA
PD630_RS07775	COG1793	dna ligase
PD630_RS07790	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PD630_RS07795	COG3360	Dodecin
PD630_RS07805	COG1376	ErfK ybiS ycfS ynhG family protein
PD630_RS07815	COG0395	ABC-type sugar transport system, permease component
PD630_RS07820	COG1653	transport
PD630_RS07825	COG3842	ATPase activity
PD630_RS07830	COG3590	peptidase
PD630_RS07860	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS07875	COG0583	DNA-binding transcription factor activity
PD630_RS07880	COG0477	Major facilitator Superfamily
PD630_RS07900	COG0477	Major facilitator Superfamily
PD630_RS07905	COG1960	acyl-CoA dehydrogenase activity
PD630_RS07920	COG0583	DNA-binding transcription factor activity
PD630_RS07925	COG0477	Major facilitator Superfamily
PD630_RS07945	COG0135	phosphoribosylanthranilate isomerase activity
PD630_RS07950	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
PD630_RS07960	COG1960	acyl-CoA dehydrogenase activity
PD630_RS07975	COG0667	Aldo Keto reductase
PD630_RS07980	COG0789	Transcriptional regulator
PD630_RS08005	COG0488	(ABC) transporter
PD630_RS08030	COG3104	oligopeptide transport
PD630_RS08040	COG1309	transcriptional regulator
PD630_RS08050	COG2353	YceI-like domain
PD630_RS08055	COG1309	transcriptional regulator
PD630_RS08060	COG2267	carboxylic ester hydrolase activity
PD630_RS08065	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PD630_RS08090	COG4585	Histidine kinase
PD630_RS08095	COG2197	response regulator
PD630_RS08120	COG0220	tRNA (guanine-N7-)-methyltransferase activity
PD630_RS08140	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
PD630_RS08175	COG0500	methyltransferase
PD630_RS08200	COG4981	capsule polysaccharide biosynthetic process
PD630_RS08215	COG1472	Belongs to the glycosyl hydrolase 3 family
PD630_RS08220	COG1309	transcriptional regulator
PD630_RS08225	COG2030	dehydratase
PD630_RS08230	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS08235	COG0183	Belongs to the thiolase family
PD630_RS08250	COG1960	acyl-CoA dehydrogenase activity
PD630_RS08265	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PD630_RS08325	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PD630_RS08345	COG0640	Transcriptional regulator
PD630_RS08405	COG1793	dna ligase
PD630_RS08405	COG3285	dna ligase
PD630_RS08420	COG3180	Ammonia monooxygenase
PD630_RS08455	COG1609	Transcriptional regulator
PD630_RS08470	COG1082	Xylose isomerase domain protein TIM barrel
PD630_RS08485	COG1268	BioY protein
PD630_RS08495	COG0183	Belongs to the thiolase family
PD630_RS08500	COG1122	ATPase activity
PD630_RS08505	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PD630_RS08510	COG0318	PFAM AMP-dependent synthetase and ligase
PD630_RS08525	COG2851	Citrate transporter
PD630_RS08530	COG0583	DNA-binding transcription factor activity
PD630_RS08550	COG0673	inositol 2-dehydrogenase activity
PD630_RS08565	COG4585	Histidine kinase
PD630_RS08585	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
PD630_RS08610	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PD630_RS08615	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PD630_RS08625	COG0022	dehydrogenase e1 component
PD630_RS08630	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PD630_RS08645	COG0745	RESPONSE REGULATOR receiver
PD630_RS08650	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PD630_RS08660	COG3938	Belongs to the proline racemase family
PD630_RS08665	COG1012	belongs to the aldehyde dehydrogenase family
PD630_RS08670	COG1012	belongs to the aldehyde dehydrogenase family
PD630_RS08690	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS08720	COG0589	response to stress
PD630_RS08725	COG2814	Major facilitator Superfamily
PD630_RS08780	COG0673	inositol 2-dehydrogenase activity
PD630_RS08785	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS08800	COG0673	inositol 2-dehydrogenase activity
PD630_RS08805	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PD630_RS08810	COG0673	inositol 2-dehydrogenase activity
PD630_RS08820	COG3962	Belongs to the TPP enzyme family
PD630_RS08830	COG2084	Dehydrogenase
PD630_RS08835	COG2186	Transcriptional regulator
PD630_RS08845	COG1129	ABC transporter
PD630_RS08850	COG4214	carbohydrate transport
PD630_RS08855	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS08865	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PD630_RS08875	COG1070	Carbohydrate kinase
PD630_RS08880	COG0546	phosphoglycolate phosphatase activity
PD630_RS08910	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PD630_RS08935	COG1063	alcohol dehydrogenase
PD630_RS08965	COG2271	Major facilitator Superfamily
PD630_RS09010	COG0252	asparaginase activity
PD630_RS09015	COG1027	Aspartate ammonia-lyase
PD630_RS09025	COG0191	fructose-bisphosphate aldolase activity
PD630_RS09045	COG0477	Major facilitator Superfamily
PD630_RS09050	COG2186	Transcriptional regulator
PD630_RS09055	COG2084	Dehydrogenase
PD630_RS09080	COG2814	Major facilitator Superfamily
PD630_RS09085	COG0183	Belongs to the thiolase family
PD630_RS09100	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS09105	COG2030	dehydratase
PD630_RS09120	COG0318	PFAM AMP-dependent synthetase and ligase
PD630_RS09145	COG1929	Belongs to the glycerate kinase type-1 family
PD630_RS09170	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PD630_RS09175	COG0601	transmembrane transport
PD630_RS09185	COG1250	3-hydroxyacyl-CoA dehydrogenase
PD630_RS09190	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
PD630_RS09195	COG1691	(AIR) carboxylase
PD630_RS09205	COG3875	lactate racemase activity
PD630_RS09210	COG3246	L-lysine catabolic process to acetate
PD630_RS09215	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS09225	COG1609	Transcriptional regulator
PD630_RS09240	COG1063	alcohol dehydrogenase
PD630_RS09250	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS09300	COG0717	Belongs to the dCTP deaminase family
PD630_RS09315	COG1864	DNA RNA non-specific endonuclease
PD630_RS09315	COG3591	Belongs to the peptidase S1B family
PD630_RS09325	COG2015	COG2015, Alkyl sulfatase and related hydrolases
PD630_RS09400	COG0519	Catalyzes the synthesis of GMP from XMP
PD630_RS09400	COG0518	GMP synthase (glutamine-hydrolyzing) activity
PD630_RS09420	COG0640	Transcriptional regulator
PD630_RS09435	COG0477	Major facilitator Superfamily
PD630_RS09445	COG0640	Transcriptional regulator
PD630_RS09475	COG1216	Glycosyl transferase, family 2
PD630_RS09515	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PD630_RS09515	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PD630_RS09545	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
PD630_RS09575	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PD630_RS09580	COG1522	sequence-specific DNA binding
PD630_RS09595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PD630_RS09600	COG3507	Belongs to the glycosyl hydrolase 43 family
PD630_RS09610	COG2814	Major facilitator Superfamily
PD630_RS09650	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PD630_RS09655	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PD630_RS09665	COG0443	Heat shock 70 kDa protein
PD630_RS09715	COG1506	peptidase
PD630_RS09715	COG0823	Involved in the tonB-independent uptake of proteins
PD630_RS09715	COG4946	Tricorn protease homolog
PD630_RS09750	COG0247	lactate metabolic process
PD630_RS09750	COG2181	nitrate reductase activity
PD630_RS09800	COG0443	Heat shock 70 kDa protein
PD630_RS09830	COG3842	ATPase activity
PD630_RS09835	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PD630_RS09860	COG1175	transmembrane transport
PD630_RS09865	COG0395	ABC-type sugar transport system, permease component
PD630_RS09875	COG2318	DinB family
PD630_RS09895	COG0443	Heat shock 70 kDa protein
PD630_RS09900	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PD630_RS09905	COG0484	heat shock protein binding
PD630_RS09910	COG0789	Transcriptional regulator
PD630_RS09925	COG4585	Histidine kinase
PD630_RS09930	COG0693	protein deglycase activity
PD630_RS09950	COG1058	Belongs to the CinA family
PD630_RS09950	COG1546	Belongs to the CinA family
PD630_RS09955	COG0318	PFAM AMP-dependent synthetase and ligase
PD630_RS09965	COG0543	2 iron, 2 sulfur cluster binding
PD630_RS09965	COG0633	Ferredoxin
PD630_RS09970	COG1017	nitric oxide dioxygenase activity
PD630_RS09970	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PD630_RS09980	COG0542	response to heat
PD630_RS10005	COG2814	Major facilitator Superfamily
PD630_RS10020	COG2072	flavoprotein involved in K transport
PD630_RS10080	COG0523	cobalamin synthesis protein
PD630_RS10085	COG0586	Pfam SNARE associated Golgi protein
PD630_RS10110	COG4129	membrane
PD630_RS10135	COG0183	Belongs to the thiolase family
PD630_RS10145	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PD630_RS10150	COG0633	Ferredoxin
PD630_RS10150	COG0543	2 iron, 2 sulfur cluster binding
PD630_RS10165	COG1994	Peptidase M50
PD630_RS10175	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PD630_RS10190	COG0601	transmembrane transport
PD630_RS10195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PD630_RS10215	COG1082	Xylose isomerase domain protein TIM barrel
PD630_RS10220	COG0402	S-adenosylhomocysteine deaminase activity
PD630_RS10225	COG0402	S-adenosylhomocysteine deaminase activity
PD630_RS10230	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PD630_RS10255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PD630_RS10260	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PD630_RS10275	COG2272	Belongs to the type-B carboxylesterase lipase family
PD630_RS10280	COG2272	Belongs to the type-B carboxylesterase lipase family
PD630_RS10285	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PD630_RS10295	COG1252	NADH dehydrogenase
PD630_RS10310	COG0166	Belongs to the GPI family
PD630_RS10330	COG0739	heme binding
PD630_RS10340	COG0045	succinate-CoA ligase (ADP-forming) activity
PD630_RS10350	COG1739	Uncharacterized protein family UPF0029
PD630_RS10400	COG1733	regulation of RNA biosynthetic process
PD630_RS10415	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
PD630_RS10425	COG2957	Belongs to the agmatine deiminase family
PD630_RS10465	COG1012	belongs to the aldehyde dehydrogenase family
PD630_RS10480	COG1309	transcriptional regulator
PD630_RS10485	COG1228	amidohydrolase
PD630_RS10505	COG2902	Dehydrogenase
PD630_RS10520	COG0679	Auxin Efflux Carrier
PD630_RS10540	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PD630_RS10545	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PD630_RS10550	COG0267	Belongs to the bacterial ribosomal protein bL33 family
PD630_RS10555	COG0227	Belongs to the bacterial ribosomal protein bL28 family
PD630_RS10565	COG0254	rRNA binding
PD630_RS10575	COG2860	membrane
PD630_RS10590	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PD630_RS10595	COG0521	Mo-molybdopterin cofactor biosynthetic process
PD630_RS10595	COG0315	cyclic pyranopterin monophosphate synthase activity
PD630_RS10620	COG1970	mechanosensitive ion channel activity
PD630_RS10635	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PD630_RS10640	COG1210	Utp--glucose-1-phosphate uridylyltransferase
PD630_RS10650	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PD630_RS10680	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PD630_RS10695	COG1132	(ABC) transporter
PD630_RS10745	COG4044	May play a role in the intracellular transport of hydrophobic ligands
PD630_RS10750	COG2235	arginine
PD630_RS10760	COG0702	epimerase
PD630_RS10765	COG1725	Transcriptional regulator
PD630_RS10775	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PD630_RS10800	COG0300	oxidoreductase activity
PD630_RS10805	COG0084	hydrolase, TatD family'
PD630_RS10815	COG1126	abc transporter atp-binding protein
PD630_RS10820	COG0765	amino acid transport
PD630_RS10825	COG3583	domain protein
PD630_RS10830	COG3583	domain protein
PD630_RS10835	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
PD630_RS10870	COG0831	urea catabolic process
PD630_RS10875	COG0832	Belongs to the urease beta subunit family
PD630_RS10880	COG0804	urea catabolic process
PD630_RS10890	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
PD630_RS10900	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PD630_RS10905	COG0488	(ABC) transporter
PD630_RS10935	COG0259	pyridoxamine-phosphate oxidase activity
PD630_RS10945	COG1414	Transcriptional regulator
PD630_RS10960	COG0395	ABC-type sugar transport system, permease component
PD630_RS10965	COG1175	transmembrane transport
PD630_RS10980	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PD630_RS10985	COG3842	ATPase activity
PD630_RS10990	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PD630_RS10995	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PD630_RS11000	COG0318	PFAM AMP-dependent synthetase and ligase
PD630_RS11005	COG0193	aminoacyl-tRNA hydrolase activity
PD630_RS11010	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
PD630_RS11025	COG1053	succinate dehydrogenase
PD630_RS11030	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PD630_RS11035	COG3572	ergothioneine biosynthetic process
PD630_RS11040	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PD630_RS11045	COG0121	glutamine amidotransferase
PD630_RS11050	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
PD630_RS11085	COG1902	pentaerythritol trinitrate reductase activity
PD630_RS11085	COG0446	pyridine nucleotide-disulphide oxidoreductase
PD630_RS11100	COG1960	acyl-CoA dehydrogenase activity
PD630_RS11110	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS11120	COG0531	amino acid
PD630_RS11155	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PD630_RS11165	COG1309	transcriptional regulator
PD630_RS11265	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
PD630_RS11300	COG0736	holo-[acyl-carrier-protein] synthase activity
PD630_RS11305	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PD630_RS11315	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PD630_RS11335	COG3956	TIGRFAM MazG family protein
PD630_RS11345	COG1216	Glycosyl transferase, family 2
PD630_RS11395	COG2837	iron assimilation
PD630_RS11405	COG0672	)-iron permease
PD630_RS11415	COG0148	phosphopyruvate hydratase activity
PD630_RS11445	COG4106	trans-aconitate 2-methyltransferase activity
PD630_RS11475	COG1846	Transcriptional regulator
PD630_RS11485	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS11495	COG2814	Major facilitator Superfamily
PD630_RS11505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PD630_RS11515	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PD630_RS11525	COG1053	succinate dehydrogenase
PD630_RS11530	COG3971	2-oxopent-4-enoate hydratase activity
PD630_RS11535	COG4569	acetaldehyde dehydrogenase (acetylating) activity
PD630_RS11540	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PD630_RS11590	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS11595	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS11610	COG1960	acyl-CoA dehydrogenase activity
PD630_RS11620	COG1309	transcriptional regulator
PD630_RS11625	COG0183	Belongs to the thiolase family
PD630_RS11630	COG1960	acyl-CoA dehydrogenase activity
PD630_RS11635	COG2030	dehydratase
PD630_RS11645	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS11650	COG0318	PFAM AMP-dependent synthetase and ligase
PD630_RS11660	COG0318	PFAM AMP-dependent synthetase and ligase
PD630_RS11675	COG1960	acyl-CoA dehydrogenase activity
PD630_RS11685	COG1960	acyl-CoA dehydrogenase activity
PD630_RS11695	COG0183	Belongs to the thiolase family
PD630_RS11705	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS11710	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS11730	COG0753	catalase activity
PD630_RS11745	COG2813	Specifically methylates the guanine in position
PD630_RS11760	COG0183	Belongs to the thiolase family
PD630_RS11765	COG2755	lipolytic protein G-D-S-L family
PD630_RS11785	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PD630_RS11800	COG0791	NLP P60 protein
PD630_RS11800	COG3883	PFAM NLP P60 protein
PD630_RS11805	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PD630_RS11815	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
PD630_RS11825	COG1331	Highly conserved protein containing a thioredoxin domain
PD630_RS11835	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PD630_RS11850	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PD630_RS11855	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
PD630_RS11860	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
PD630_RS11895	COG1570	exodeoxyribonuclease VII activity
PD630_RS11915	COG1322	Protein conserved in bacteria
PD630_RS11920	COG0420	3'-5' exonuclease activity
PD630_RS11925	COG0419	ATPase involved in DNA repair
PD630_RS11940	COG1966	Carbon starvation protein
PD630_RS11945	COG0069	glutamate synthase activity
PD630_RS11955	COG0012	GTP binding
PD630_RS11995	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PD630_RS12015	COG0326	Molecular chaperone. Has ATPase activity
PD630_RS12035	COG1960	acyl-CoA dehydrogenase activity
PD630_RS12040	COG2226	methyltransferase
PD630_RS12050	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
PD630_RS12050	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
PD630_RS12075	COG1574	metal-dependent hydrolase with the TIM-barrel fold
PD630_RS12090	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PD630_RS12105	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PD630_RS12110	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PD630_RS12115	COG0649	NAD binding
PD630_RS12130	COG1034	ATP synthesis coupled electron transport
PD630_RS12135	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
PD630_RS12140	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PD630_RS12170	COG3757	hydrolase, family 25
PD630_RS12180	COG1846	Transcriptional regulator
PD630_RS12195	COG1051	belongs to the nudix hydrolase family
PD630_RS12200	COG2154	pterin-4-alpha-carbinolamine dehydratase
PD630_RS12210	COG1217	gtp-binding protein TYPA
PD630_RS12215	COG0747	negative chemotaxis
PD630_RS12220	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
PD630_RS12265	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
PD630_RS12300	COG1012	belongs to the aldehyde dehydrogenase family
PD630_RS12305	COG0506	proline dehydrogenase activity
PD630_RS12315	COG0318	PFAM AMP-dependent synthetase and ligase
PD630_RS12320	COG2130	NADP-dependent
PD630_RS12325	COG3835	regulator
PD630_RS12365	COG1113	amino acid transport
PD630_RS12370	COG2171	N-acyltransferase activity
PD630_RS12385	COG1611	Belongs to the LOG family
PD630_RS12390	COG1611	Belongs to the LOG family
PD630_RS12395	COG0318	PFAM AMP-dependent synthetase and ligase
PD630_RS12400	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PD630_RS12405	COG0463	Glycosyl transferase, family 2
PD630_RS12415	COG0519	Catalyzes the synthesis of GMP from XMP
PD630_RS12425	COG0297	glycogen (starch) synthase activity
PD630_RS12430	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PD630_RS12440	COG1595	DNA-templated transcription, initiation
PD630_RS12445	COG5662	AntiSigma factor
PD630_RS12450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PD630_RS12480	COG2239	Acts as a magnesium transporter
PD630_RS12485	COG2301	Belongs to the HpcH HpaI aldolase family
PD630_RS12515	COG0477	Major facilitator Superfamily
PD630_RS12540	COG0598	Magnesium transport protein CorA
PD630_RS12545	COG0613	PHP domain protein
PD630_RS12560	COG1174	glycine betaine transport
PD630_RS12565	COG1174	glycine betaine transport
PD630_RS12570	COG0517	IMP dehydrogenase activity
PD630_RS12570	COG1125	glycine betaine transport
PD630_RS12600	COG1309	transcriptional regulator
PD630_RS12620	COG1132	(ABC) transporter
PD630_RS12635	COG0076	glutamate decarboxylase activity
PD630_RS12655	COG0435	Glutathione S-transferase
PD630_RS12675	COG0277	FAD linked oxidase domain protein
PD630_RS12685	COG0318	PFAM AMP-dependent synthetase and ligase
PD630_RS12690	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
PD630_RS12725	COG1022	Amp-dependent synthetase and ligase
PD630_RS12740	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PD630_RS12755	COG2318	DinB family
PD630_RS12760	COG0366	Alpha amylase catalytic
PD630_RS12765	COG3281	Trehalose synthase
PD630_RS12770	COG1132	(ABC) transporter
PD630_RS12780	COG3012	SEC-C Motif Domain Protein
PD630_RS12785	COG0318	PFAM AMP-dependent synthetase and ligase
PD630_RS12800	COG0577	efflux transmembrane transporter activity
PD630_RS12800	COG1136	(ABC) transporter
PD630_RS12805	COG0577	efflux transmembrane transporter activity
PD630_RS12805	COG1136	(ABC) transporter
PD630_RS12815	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
PD630_RS12850	COG0542	response to heat
PD630_RS12860	COG1454	alcohol dehydrogenase
PD630_RS12865	COG4585	Histidine kinase
PD630_RS12870	COG2197	response regulator
PD630_RS12875	COG1131	(ABC) transporter
PD630_RS12880	COG3559	Exporter of polyketide antibiotics
PD630_RS12920	COG0535	radical SAM domain protein
PD630_RS12935	COG0446	pyridine nucleotide-disulphide oxidoreductase
PD630_RS12935	COG1902	pentaerythritol trinitrate reductase activity
PD630_RS12945	COG0446	pyridine nucleotide-disulphide oxidoreductase
PD630_RS12945	COG1902	pentaerythritol trinitrate reductase activity
PD630_RS12980	COG0531	amino acid
PD630_RS12985	COG4303	Ethanolamine ammonia lyase large subunit
PD630_RS13000	COG0477	Major facilitator Superfamily
PD630_RS13005	COG0318	PFAM AMP-dependent synthetase and ligase
PD630_RS13020	COG4585	Histidine kinase
PD630_RS13025	COG2197	response regulator
PD630_RS13040	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PD630_RS13050	COG1960	acyl-CoA dehydrogenase activity
PD630_RS13055	COG2030	dehydratase
PD630_RS13065	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PD630_RS13080	COG0287	Prephenate dehydrogenase
PD630_RS13085	COG0512	Glutamine amidotransferase of anthranilate synthase
PD630_RS13085	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PD630_RS13090	COG1605	Chorismate mutase
PD630_RS13095	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
PD630_RS13105	COG1960	acyl-CoA dehydrogenase activity
PD630_RS13125	COG0183	Belongs to the thiolase family
PD630_RS13130	COG1024	Enoyl-CoA hydratase
PD630_RS13130	COG1250	3-hydroxyacyl-CoA dehydrogenase
PD630_RS13140	COG1024	Enoyl-CoA hydratase
PD630_RS13155	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PD630_RS13215	COG0051	transcription antitermination factor activity, RNA binding
PD630_RS13220	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PD630_RS13225	COG0088	Forms part of the polypeptide exit tunnel
PD630_RS13235	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PD630_RS13240	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PD630_RS13275	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PD630_RS13280	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PD630_RS13300	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PD630_RS13315	COG0200	Binds to the 23S rRNA
PD630_RS13325	COG0563	adenylate kinase activity
PD630_RS13335	COG1490	D-aminoacyl-tRNA deacylase activity
PD630_RS13340	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PD630_RS13345	COG0257	Belongs to the bacterial ribosomal protein bL36 family
PD630_RS13365	COG0202	RNA polymerase activity
PD630_RS13370	COG0203	ribosomal protein L17
PD630_RS13375	COG0101	tRNA pseudouridine synthase activity
PD630_RS13390	COG3266	domain, Protein
PD630_RS13395	COG1404	Belongs to the peptidase S8 family
PD630_RS13405	COG1674	ftsk spoiiie
PD630_RS13420	COG4842	Belongs to the WXG100 family
PD630_RS13425	COG1522	sequence-specific DNA binding
PD630_RS13430	COG1834	amidinotransferase
PD630_RS13435	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PD630_RS13440	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PD630_RS13450	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PD630_RS13475	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
PD630_RS13510	COG0456	acetyltransferase
PD630_RS13515	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PD630_RS13535	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PD630_RS13540	COG0459	protein refolding
PD630_RS13550	COG1595	DNA-templated transcription, initiation
PD630_RS13590	COG0516	GMP reductase activity
PD630_RS13600	COG0518	GMP synthase (glutamine-hydrolyzing) activity
PD630_RS13600	COG0519	Catalyzes the synthesis of GMP from XMP
PD630_RS13660	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PD630_RS13670	COG0596	Alpha beta hydrolase
PD630_RS13675	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PD630_RS13710	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PD630_RS13715	COG1120	ATPase activity
PD630_RS13725	COG0587	DNA-directed DNA polymerase activity
PD630_RS13750	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
PD630_RS13760	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PD630_RS13770	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PD630_RS13785	COG2814	Major facilitator Superfamily
PD630_RS13790	COG0708	Exodeoxyribonuclease III
PD630_RS13795	COG0180	Tryptophanyl-tRNA synthetase
PD630_RS13800	COG1295	ribonuclease BN
PD630_RS13805	COG1686	Belongs to the peptidase S11 family
PD630_RS13810	COG0039	L-malate dehydrogenase activity
PD630_RS13815	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
PD630_RS13820	COG1053	succinate dehydrogenase
PD630_RS13830	COG2009	succinate dehydrogenase
PD630_RS13865	COG0791	NLP P60 protein
PD630_RS13875	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PD630_RS13880	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PD630_RS13900	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
PD630_RS13900	COG1473	amidohydrolase
PD630_RS13915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PD630_RS13920	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PD630_RS13950	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
PD630_RS13955	COG1201	RNA secondary structure unwinding
PD630_RS13980	COG1012	belongs to the aldehyde dehydrogenase family
PD630_RS13990	COG1522	sequence-specific DNA binding
PD630_RS14025	COG4770	biotin carboxylase activity
PD630_RS14070	COG0477	Major facilitator Superfamily
PD630_RS14075	COG0424	maF-like protein
PD630_RS14085	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PD630_RS14105	COG0745	RESPONSE REGULATOR receiver
PD630_RS14110	COG5002	protein histidine kinase activity
PD630_RS14125	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PD630_RS14140	COG1316	TRANSCRIPTIONal
PD630_RS14155	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
PD630_RS14170	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
PD630_RS14170	COG0778	Nitroreductase
PD630_RS14175	COG0391	Required for morphogenesis under gluconeogenic growth conditions
PD630_RS14195	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PD630_RS14205	COG1482	cell wall glycoprotein biosynthetic process
PD630_RS14215	COG0531	amino acid
PD630_RS14220	COG1309	transcriptional regulator
PD630_RS14240	COG5002	protein histidine kinase activity
PD630_RS14245	COG5401	PFAM Sporulation and spore germination
PD630_RS14255	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PD630_RS14260	COG0653	protein targeting
PD630_RS14270	COG1011	Hydrolase
PD630_RS14300	COG1162	GTPase activity
PD630_RS14305	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
PD630_RS14310	COG2135	peptidase activity
PD630_RS14325	COG5662	AntiSigma factor
PD630_RS14330	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
PD630_RS14360	COG0406	alpha-ribazole phosphatase activity
PD630_RS14365	COG1192	Involved in chromosome partitioning
PD630_RS14395	COG0513	Belongs to the DEAD box helicase family
PD630_RS14430	COG2186	Transcriptional regulator
PD630_RS14445	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PD630_RS14445	COG2146	nitrite reductase [NAD(P)H] activity
PD630_RS14465	COG0303	'Molybdopterin
PD630_RS14470	COG2188	Transcriptional regulator
PD630_RS14485	COG0596	Alpha beta hydrolase
PD630_RS14490	COG0210	DNA helicase
PD630_RS14530	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
PD630_RS14545	COG3480	Lon protease (S16) C-terminal proteolytic domain
PD630_RS14555	COG1615	UPF0182 protein
PD630_RS14560	COG1388	LysM domain
PD630_RS14565	COG1388	LysM domain
PD630_RS14580	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PD630_RS14595	COG0318	PFAM AMP-dependent synthetase and ligase
PD630_RS14600	COG1960	acyl-CoA dehydrogenase activity
PD630_RS14610	COG0483	inositol monophosphate 1-phosphatase activity
PD630_RS14620	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PD630_RS14625	COG0668	transmembrane transport
PD630_RS14635	COG2884	Cell division ATP-binding protein ftsE
PD630_RS14640	COG2177	Part of the ABC transporter FtsEX involved in
PD630_RS14645	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
PD630_RS14655	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PD630_RS14660	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PD630_RS14705	COG1846	Transcriptional regulator
PD630_RS14710	COG2267	carboxylic ester hydrolase activity
PD630_RS14720	COG0778	Nitroreductase
PD630_RS14725	COG0513	Belongs to the DEAD box helicase family
PD630_RS14730	COG0314	molybdopterin synthase activity
PD630_RS14735	COG0521	Mo-molybdopterin cofactor biosynthetic process
PD630_RS14735	COG0315	cyclic pyranopterin monophosphate synthase activity
PD630_RS14745	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PD630_RS14760	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
PD630_RS14775	COG1309	transcriptional regulator
PD630_RS14795	COG1780	Probably involved in ribonucleotide reductase function
PD630_RS14805	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PD630_RS14820	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PD630_RS14825	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PD630_RS14845	COG1523	belongs to the glycosyl hydrolase 13 family
PD630_RS14850	COG1119	ATPase activity
PD630_RS14865	COG2226	methyltransferase
PD630_RS14880	COG0110	maltose O-acetyltransferase activity
PD630_RS14900	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PD630_RS14910	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
PD630_RS14930	COG0482	sulfurtransferase activity
PD630_RS14940	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PD630_RS14965	COG0154	amidase activity
PD630_RS14985	COG2197	response regulator
PD630_RS14990	COG0205	6-phosphofructokinase activity
PD630_RS14995	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PD630_RS15005	COG2259	Doxx family
PD630_RS15010	COG0531	amino acid
PD630_RS15015	COG0129	dihydroxy-acid dehydratase activity
PD630_RS15030	COG0440	acetolactate synthase activity
PD630_RS15035	COG2271	Major facilitator Superfamily
PD630_RS15040	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS15045	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PD630_RS15055	COG0473	3-isopropylmalate dehydrogenase activity
PD630_RS15060	COG2271	Major facilitator Superfamily
PD630_RS15065	COG0179	Fumarylacetoacetate (FAA) hydrolase
PD630_RS15070	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PD630_RS15090	COG1414	Transcriptional regulator
PD630_RS15095	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PD630_RS15100	COG0066	3-isopropylmalate dehydratase activity
PD630_RS15110	COG0494	nUDIX hydrolase
PD630_RS15110	COG0406	alpha-ribazole phosphatase activity
PD630_RS15115	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PD630_RS15125	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
PD630_RS15130	COG0626	cystathionine gamma-synthase activity
PD630_RS15135	COG1181	Belongs to the D-alanine--D-alanine ligase family
PD630_RS15160	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PD630_RS15165	COG1024	Enoyl-CoA hydratase
PD630_RS15165	COG1250	3-hydroxyacyl-CoA dehydrogenase
PD630_RS15170	COG1461	Dihydroxyacetone kinase
PD630_RS15175	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PD630_RS15180	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
PD630_RS15185	COG0742	ribosomal rna small subunit methyltransferase
PD630_RS15190	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PD630_RS15205	COG0571	ribonuclease III activity
PD630_RS15210	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
PD630_RS15230	COG1254	Belongs to the acylphosphatase family
PD630_RS15255	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
PD630_RS15270	COG0228	four-way junction DNA binding
PD630_RS15280	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PD630_RS15285	COG0336	Belongs to the RNA methyltransferase TrmD family
PD630_RS15315	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PD630_RS15330	COG0477	Major facilitator Superfamily
PD630_RS15350	COG0792	nuclease activity
PD630_RS15365	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PD630_RS15375	COG2814	Major facilitator Superfamily
PD630_RS15380	COG4974	Belongs to the 'phage' integrase family
PD630_RS15395	COG0052	Belongs to the universal ribosomal protein uS2 family
PD630_RS15400	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PD630_RS15405	COG0528	UMP kinase activity
PD630_RS15410	COG0233	cytoplasmic translational termination
PD630_RS15420	COG2226	methyltransferase
PD630_RS15435	COG0820	rRNA (adenine-C2-)-methyltransferase activity
PD630_RS15445	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
PD630_RS15485	COG0531	amino acid
PD630_RS15490	COG2197	response regulator
PD630_RS15495	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PD630_RS15525	COG2188	Transcriptional regulator
PD630_RS15535	COG1492	cobalamin metabolic process
PD630_RS15545	COG1131	(ABC) transporter
PD630_RS15550	COG2188	Transcriptional regulator
PD630_RS15560	COG1742	UPF0060 membrane protein
PD630_RS15575	COG0579	oxidoreductase
PD630_RS15605	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PD630_RS15605	COG1648	precorrin-2 dehydrogenase activity
PD630_RS15630	COG3290	protein histidine kinase activity
PD630_RS15650	COG0589	response to stress
PD630_RS15655	COG3022	response to hydroperoxide
PD630_RS15660	COG0442	prolyl-tRNA aminoacylation
PD630_RS15685	COG2267	carboxylic ester hydrolase activity
PD630_RS15705	COG2197	response regulator
PD630_RS15715	COG1131	(ABC) transporter
PD630_RS15745	COG0779	Required for maturation of 30S ribosomal subunits
PD630_RS15765	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PD630_RS15770	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
PD630_RS15780	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
PD630_RS15790	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PD630_RS15805	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PD630_RS15810	COG1185	polyribonucleotide nucleotidyltransferase activity
PD630_RS15825	COG0583	DNA-binding transcription factor activity
PD630_RS15830	COG2814	Major facilitator Superfamily
PD630_RS15855	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PD630_RS15855	COG0512	Glutamine amidotransferase of anthranilate synthase
PD630_RS15860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PD630_RS15870	COG0644	oxidoreductase
PD630_RS15890	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PD630_RS15900	COG4977	sequence-specific DNA binding
PD630_RS15950	COG2264	protein methyltransferase activity
PD630_RS15965	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
PD630_RS15980	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
PD630_RS16025	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PD630_RS16035	COG1674	ftsk spoiiie
PD630_RS16050	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
PD630_RS16060	COG1058	Belongs to the CinA family
PD630_RS16060	COG1546	Belongs to the CinA family
PD630_RS16065	COG1396	sequence-specific DNA binding
PD630_RS16070	COG1842	Phage shock protein A
PD630_RS16085	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
PD630_RS16110	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PD630_RS16115	COG2137	regulation of response to DNA damage stimulus
PD630_RS16120	COG0765	amino acid transport
PD630_RS16125	COG0765	amino acid transport
PD630_RS16130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PD630_RS16135	COG1126	abc transporter atp-binding protein
PD630_RS16140	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PD630_RS16150	COG1196	nuclear chromosome segregation
PD630_RS16160	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PD630_RS16175	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PD630_RS16185	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
PD630_RS16195	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PD630_RS16195	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PD630_RS16200	COG1105	Belongs to the carbohydrate kinase PfkB family
PD630_RS16205	COG1349	DNA-binding transcription factor activity
PD630_RS16210	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PD630_RS16215	COG2233	PERMEase
PD630_RS16220	COG1960	acyl-CoA dehydrogenase activity
PD630_RS16240	COG1643	Atp-dependent helicase
PD630_RS16260	COG0477	Major facilitator Superfamily
PD630_RS16265	COG0569	domain protein
PD630_RS16265	COG0475	glutathione-regulated potassium exporter activity
PD630_RS16270	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PD630_RS16290	COG0583	DNA-binding transcription factor activity
PD630_RS16345	COG0123	including yeast histone deacetylase and acetoin utilization protein
PD630_RS16350	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PD630_RS16350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PD630_RS16400	COG0475	glutathione-regulated potassium exporter activity
PD630_RS16435	COG0756	dUTP diphosphatase activity
PD630_RS16470	COG0569	domain protein
PD630_RS16475	COG0531	amino acid
PD630_RS16480	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PD630_RS16505	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
PD630_RS16505	COG2066	Belongs to the glutaminase family
PD630_RS16510	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PD630_RS16515	COG0477	Major facilitator Superfamily
PD630_RS16525	COG2188	Transcriptional regulator
PD630_RS16550	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
PD630_RS16555	COG1024	Enoyl-CoA hydratase
PD630_RS16555	COG1250	3-hydroxyacyl-CoA dehydrogenase
PD630_RS16560	COG0183	Belongs to the thiolase family
PD630_RS16565	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
PD630_RS16575	COG0657	acetylesterase activity
PD630_RS16585	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
PD630_RS16595	COG3253	May function as heme-dependent peroxidase
PD630_RS16605	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PD630_RS16640	COG2223	nitrite transmembrane transporter activity
PD630_RS16680	COG1690	Belongs to the RtcB family
PD630_RS16690	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PD630_RS16705	COG1560	Kdo2-lipid A biosynthetic process
PD630_RS16710	COG0438	transferase activity, transferring glycosyl groups
PD630_RS16715	COG1051	belongs to the nudix hydrolase family
PD630_RS16720	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
PD630_RS16725	COG1946	Acyl-CoA thioesterase
PD630_RS16735	COG1946	Acyl-CoA thioesterase
PD630_RS16760	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
PD630_RS16770	COG2255	four-way junction helicase activity
PD630_RS16785	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PD630_RS16790	COG0747	negative chemotaxis
PD630_RS16795	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PD630_RS16800	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PD630_RS16805	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PD630_RS16810	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PD630_RS16820	COG0124	histidyl-tRNA synthetase
PD630_RS16885	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
PD630_RS16890	COG1716	ATPase activity
PD630_RS16890	COG1131	(ABC) transporter
PD630_RS16890	COG0842	Transport permease protein
PD630_RS16975	COG0446	pyridine nucleotide-disulphide oxidoreductase
PD630_RS16980	COG0189	ligase activity
PD630_RS16990	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PD630_RS16990	COG0543	2 iron, 2 sulfur cluster binding
PD630_RS17000	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
PD630_RS17005	COG2146	nitrite reductase [NAD(P)H] activity
PD630_RS17015	COG3350	monooxygenase activity
PD630_RS17020	COG1012	belongs to the aldehyde dehydrogenase family
PD630_RS17025	COG0625	glutathione transferase activity
PD630_RS17040	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PD630_RS17050	COG1846	Transcriptional regulator
PD630_RS17055	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PD630_RS17065	COG0183	Belongs to the thiolase family
PD630_RS17090	COG0625	glutathione transferase activity
PD630_RS17095	COG1012	belongs to the aldehyde dehydrogenase family
PD630_RS17100	COG0189	ligase activity
PD630_RS17120	COG0657	acetylesterase activity
PD630_RS17180	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PD630_RS17215	COG0657	acetylesterase activity
PD630_RS17255	COG0656	L-ascorbic acid biosynthetic process
PD630_RS17270	COG1082	Xylose isomerase domain protein TIM barrel
PD630_RS17270	COG3185	4-Hydroxyphenylpyruvate dioxygenase
PD630_RS17275	COG1609	Transcriptional regulator
PD630_RS17280	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PD630_RS17285	COG0477	Major facilitator Superfamily
PD630_RS17290	COG1024	Enoyl-CoA hydratase
PD630_RS17295	COG4670	ketone body catabolic process
PD630_RS17300	COG1609	Transcriptional regulator
PD630_RS17310	COG1012	belongs to the aldehyde dehydrogenase family
PD630_RS17315	COG0477	Major facilitator Superfamily
PD630_RS17325	COG1940	carbohydrate kinase activity
PD630_RS17350	COG1024	Enoyl-CoA hydratase
PD630_RS17375	COG1012	belongs to the aldehyde dehydrogenase family
PD630_RS17380	COG0563	adenylate kinase activity
PD630_RS17400	COG2814	Major facilitator Superfamily
PD630_RS17405	COG2207	Transcriptional regulator
PD630_RS17415	COG1609	Transcriptional regulator
PD630_RS17420	COG0477	Major facilitator Superfamily
PD630_RS17425	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PD630_RS17430	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS17435	COG1250	3-hydroxyacyl-CoA dehydrogenase
PD630_RS17445	COG2814	Major facilitator Superfamily
PD630_RS17465	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PD630_RS17475	COG2072	flavoprotein involved in K transport
PD630_RS17495	COG1012	belongs to the aldehyde dehydrogenase family
PD630_RS17510	COG1960	acyl-CoA dehydrogenase activity
PD630_RS17535	COG1509	lysine 2,3-aminomutase activity
PD630_RS17550	COG3486	L-lysine 6-monooxygenase (NADPH) activity
PD630_RS17555	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PD630_RS17555	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PD630_RS17570	COG1181	Belongs to the D-alanine--D-alanine ligase family
PD630_RS17610	COG1737	Transcriptional regulator
PD630_RS17620	COG0477	Major facilitator Superfamily
PD630_RS17625	COG0402	S-adenosylhomocysteine deaminase activity
PD630_RS17635	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
PD630_RS17640	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
PD630_RS17670	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PD630_RS17685	COG2318	DinB family
PD630_RS17690	COG0477	Major facilitator Superfamily
PD630_RS17695	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PD630_RS17715	COG0583	DNA-binding transcription factor activity
PD630_RS17720	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
PD630_RS17730	COG2301	Belongs to the HpcH HpaI aldolase family
PD630_RS17735	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PD630_RS17750	COG2828	Protein conserved in bacteria
PD630_RS17760	COG0583	DNA-binding transcription factor activity
PD630_RS17765	COG1233	COG1233 Phytoene dehydrogenase and related
PD630_RS17770	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
PD630_RS17810	COG0318	PFAM AMP-dependent synthetase and ligase
PD630_RS17840	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PD630_RS17855	COG3473	Maleate cis-trans isomerase
PD630_RS17860	COG0179	Fumarylacetoacetate (FAA) hydrolase
PD630_RS17880	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PD630_RS17895	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PD630_RS17900	COG0657	acetylesterase activity
PD630_RS17935	COG0640	Transcriptional regulator
PD630_RS18100	COG2226	methyltransferase
PD630_RS18120	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PD630_RS18135	COG0443	Heat shock 70 kDa protein
PD630_RS18140	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PD630_RS18145	COG0484	heat shock protein binding
PD630_RS18155	COG0456	acetyltransferase
PD630_RS18160	COG0492	ferredoxin-NADP+ reductase activity
PD630_RS18175	COG1595	DNA-templated transcription, initiation
PD630_RS18205	COG1278	Cold shock
PD630_RS18215	COG0251	oxidation-reduction process
PD630_RS18250	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
PD630_RS18280	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PD630_RS18285	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PD630_RS18295	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PD630_RS18305	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PD630_RS18310	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PD630_RS18335	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PD630_RS18345	COG0540	Belongs to the ATCase OTCase family
PD630_RS18360	COG0505	Belongs to the CarA family
PD630_RS18370	COG0284	orotidine-5'-phosphate decarboxylase activity
PD630_RS18380	COG0194	GDP metabolic process
PD630_RS18405	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PD630_RS18465	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PD630_RS18465	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PD630_RS18480	COG0322	excinuclease ABC activity
PD630_RS18485	COG1660	Displays ATPase and GTPase activities
PD630_RS18500	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PD630_RS18505	COG0126	phosphoglycerate kinase activity
PD630_RS18510	COG0149	triose-phosphate isomerase activity
PD630_RS18520	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PD630_RS18540	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PD630_RS18550	COG0109	protoheme IX farnesyltransferase activity
PD630_RS18605	COG0396	ATPase activity
PD630_RS18615	COG0822	iron-sulfur transferase activity
PD630_RS18620	COG2151	metal-sulfur cluster biosynthetic enzyme
PD630_RS18635	COG0488	(ABC) transporter
PD630_RS18645	COG1309	transcriptional regulator
PD630_RS18650	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
PD630_RS18660	COG0791	NLP P60 protein
PD630_RS18660	COG3883	PFAM NLP P60 protein
PD630_RS18665	COG0714	Associated with various cellular activities
PD630_RS18675	COG2304	oxidoreductase activity
PD630_RS18685	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
PD630_RS18690	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
PD630_RS18720	COG3321	synthase
PD630_RS18720	COG0604	alcohol dehydrogenase
PD630_RS18725	COG0318	PFAM AMP-dependent synthetase and ligase
PD630_RS18725	COG0300	oxidoreductase activity
PD630_RS18725	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PD630_RS18725	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS18725	COG3321	synthase
PD630_RS18730	COG0318	PFAM AMP-dependent synthetase and ligase
PD630_RS18800	COG1253	flavin adenine dinucleotide binding
PD630_RS18805	COG1253	flavin adenine dinucleotide binding
PD630_RS18815	COG0697	spore germination
PD630_RS18820	COG0513	Belongs to the DEAD box helicase family
PD630_RS18825	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PD630_RS18830	COG0513	Belongs to the DEAD box helicase family
PD630_RS18845	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PD630_RS18850	COG1120	ATPase activity
PD630_RS18855	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PD630_RS18860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PD630_RS18875	COG1252	NADH dehydrogenase
PD630_RS18900	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
PD630_RS18905	COG1396	sequence-specific DNA binding
PD630_RS18925	COG3177	Filamentation induced by cAMP protein fic
PD630_RS18930	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PD630_RS18935	COG1121	(ABC) transporter
PD630_RS18940	COG0803	Belongs to the bacterial solute-binding protein 9 family
PD630_RS18945	COG0596	Alpha beta hydrolase
PD630_RS18990	COG1793	dna ligase
PD630_RS18990	COG3285	dna ligase
PD630_RS19000	COG2239	Acts as a magnesium transporter
PD630_RS19075	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PD630_RS19140	COG0517	IMP dehydrogenase activity
PD630_RS19195	COG2814	Major facilitator Superfamily
PD630_RS19200	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PD630_RS19205	COG0642	Histidine kinase
PD630_RS19210	COG0745	RESPONSE REGULATOR receiver
PD630_RS19215	COG0671	phosphoesterase, PA-phosphatase related
PD630_RS19230	COG1063	alcohol dehydrogenase
PD630_RS19245	COG0477	Major facilitator Superfamily
PD630_RS19255	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
PD630_RS19260	COG0251	oxidation-reduction process
PD630_RS19285	COG0628	permease
PD630_RS19310	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
PD630_RS19340	COG1278	Cold shock
PD630_RS19345	COG0783	Belongs to the Dps family
PD630_RS19380	COG2318	DinB family
PD630_RS19415	COG3795	YCII-related domain
PD630_RS19420	COG4941	Belongs to the sigma-70 factor family
PD630_RS19470	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PD630_RS19495	COG2080	2 iron, 2 sulfur cluster binding
PD630_RS19500	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
PD630_RS19505	COG1529	Aldehyde oxidase and xanthine dehydrogenase
PD630_RS19525	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS19555	COG0463	Glycosyl transferase, family 2
PD630_RS19580	COG2197	response regulator
PD630_RS19635	COG4585	Histidine kinase
PD630_RS19670	COG3226	Transcriptional regulator
PD630_RS19720	COG0583	DNA-binding transcription factor activity
PD630_RS19775	COG1388	LysM domain
PD630_RS19785	COG0318	PFAM AMP-dependent synthetase and ligase
PD630_RS19815	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PD630_RS19905	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PD630_RS19910	COG4221	oxidoreductase activity
PD630_RS19925	COG0673	inositol 2-dehydrogenase activity
PD630_RS19960	COG4213	ABC transporter substrate-binding protein
PD630_RS19970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PD630_RS20000	COG0667	Aldo Keto reductase
PD630_RS20005	COG2207	Transcriptional regulator
PD630_RS20010	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS20030	COG5522	Integral membrane protein (intg_mem_TP0381)
PD630_RS20040	COG0772	Belongs to the SEDS family
PD630_RS20055	COG0686	Belongs to the AlaDH PNT family
PD630_RS20060	COG1113	amino acid transport
PD630_RS20065	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PD630_RS20070	COG0318	PFAM AMP-dependent synthetase and ligase
PD630_RS20095	COG1607	acyl-coa hydrolase
PD630_RS20100	COG2072	flavoprotein involved in K transport
PD630_RS20105	COG1012	belongs to the aldehyde dehydrogenase family
PD630_RS20115	COG1024	Enoyl-CoA hydratase
PD630_RS20140	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
PD630_RS20155	COG0657	acetylesterase activity
PD630_RS20175	COG0277	FAD linked oxidase domain protein
PD630_RS20185	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PD630_RS20200	COG2124	cytochrome p450
PD630_RS20225	COG0387	Pfam Sodium calcium exchanger
PD630_RS20275	COG2358	TRAP transporter, solute receptor (TAXI family
PD630_RS20280	COG1116	anion transmembrane transporter activity
PD630_RS20285	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PD630_RS20355	COG4585	Histidine kinase
PD630_RS20380	COG2072	flavoprotein involved in K transport
PD630_RS20395	COG2076	Multidrug Resistance protein
PD630_RS20405	COG2315	Protein conserved in bacteria
PD630_RS20425	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PD630_RS20430	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS20435	COG2271	Major facilitator Superfamily
PD630_RS20450	COG0318	PFAM AMP-dependent synthetase and ligase
PD630_RS20460	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS20465	COG0277	FAD linked oxidase domain protein
PD630_RS20490	COG3119	arylsulfatase activity
PD630_RS20510	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS20605	COG0477	Major facilitator Superfamily
PD630_RS20610	COG2188	Transcriptional regulator
PD630_RS20615	COG1960	acyl-CoA dehydrogenase activity
PD630_RS20620	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PD630_RS20635	COG1012	belongs to the aldehyde dehydrogenase family
PD630_RS20645	COG1024	Enoyl-CoA hydratase
PD630_RS20660	COG1414	Transcriptional regulator
PD630_RS20670	COG0596	Alpha beta hydrolase
PD630_RS20680	COG0473	3-isopropylmalate dehydrogenase activity
PD630_RS20685	COG0640	Transcriptional regulator
PD630_RS20705	COG1846	Transcriptional regulator
PD630_RS20715	COG2897	thiosulfate sulfurtransferase activity
PD630_RS20730	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
PD630_RS20755	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
PD630_RS20760	COG1012	belongs to the aldehyde dehydrogenase family
PD630_RS20780	COG1113	amino acid transport
PD630_RS20785	COG0277	FAD linked oxidase domain protein
PD630_RS20785	COG0247	lactate metabolic process
PD630_RS20795	COG3835	regulator
PD630_RS20800	COG1012	belongs to the aldehyde dehydrogenase family
PD630_RS20805	COG0506	proline dehydrogenase activity
PD630_RS20825	COG0318	PFAM AMP-dependent synthetase and ligase
PD630_RS20890	COG1063	alcohol dehydrogenase
PD630_RS20910	COG0477	Major facilitator Superfamily
PD630_RS20920	COG1063	alcohol dehydrogenase
PD630_RS20925	COG0477	Major facilitator Superfamily
PD630_RS20930	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PD630_RS20940	COG3618	amidohydrolase
PD630_RS20945	COG0477	Major facilitator Superfamily
PD630_RS20955	COG0318	PFAM AMP-dependent synthetase and ligase
PD630_RS20960	COG0477	Major facilitator Superfamily
PD630_RS20965	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
PD630_RS20970	COG1609	Transcriptional regulator
PD630_RS20975	COG1960	acyl-CoA dehydrogenase activity
PD630_RS20980	COG1024	Enoyl-CoA hydratase
PD630_RS20985	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PD630_RS20995	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PD630_RS21000	COG1250	3-hydroxyacyl-CoA dehydrogenase
PD630_RS21015	COG0508	dehydrogenase complex catalyzes the overall conversion of
PD630_RS21015	COG0596	Alpha beta hydrolase
PD630_RS21040	COG0657	acetylesterase activity
PD630_RS21050	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PD630_RS21060	COG0667	Aldo Keto reductase
PD630_RS21065	COG1024	Enoyl-CoA hydratase
PD630_RS21070	COG0318	PFAM AMP-dependent synthetase and ligase
PD630_RS21100	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS21105	COG1960	acyl-CoA dehydrogenase activity
PD630_RS21115	COG0477	Major facilitator Superfamily
PD630_RS21120	COG3842	ATPase activity
PD630_RS21180	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
PD630_RS21210	COG0454	-acetyltransferase
PD630_RS21220	COG1569	PIN domain
PD630_RS21225	COG3311	Transcriptional regulator
PD630_RS21245	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PD630_RS21250	COG0604	alcohol dehydrogenase
PD630_RS21275	COG0753	catalase activity
PD630_RS21280	COG3284	Transcriptional regulator
PD630_RS21285	COG3350	monooxygenase activity
PD630_RS21290	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PD630_RS21320	COG0459	protein refolding
PD630_RS21330	COG0277	FAD linked oxidase domain protein
PD630_RS21350	COG2329	Antibiotic biosynthesis monooxygenase
PD630_RS21365	COG0281	malic enzyme
PD630_RS21375	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PD630_RS21375	COG1017	nitric oxide dioxygenase activity
PD630_RS21380	COG2814	Major facilitator Superfamily
PD630_RS21400	COG3473	Maleate cis-trans isomerase
PD630_RS21405	COG0145	ligase activity
PD630_RS21425	COG1309	transcriptional regulator
PD630_RS21450	COG2197	response regulator
PD630_RS21470	COG3485	protocatechuate 3,4-dioxygenase
PD630_RS21505	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
PD630_RS21530	COG1073	alpha beta
PD630_RS21535	COG1073	alpha beta
PD630_RS21545	COG0500	methyltransferase
PD630_RS21550	COG3795	YCII-related domain
PD630_RS21595	COG0583	DNA-binding transcription factor activity
PD630_RS21615	COG0778	Nitroreductase
PD630_RS21620	COG2814	Major facilitator Superfamily
PD630_RS21635	COG0656	L-ascorbic acid biosynthetic process
PD630_RS21655	COG3257	ureidoglycine aminohydrolase activity
PD630_RS21665	COG2149	membrane
PD630_RS21670	COG0583	DNA-binding transcription factor activity
PD630_RS21680	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PD630_RS21685	COG2271	Major facilitator Superfamily
PD630_RS21705	COG2271	Major facilitator Superfamily
PD630_RS21710	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PD630_RS21715	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PD630_RS21720	COG1024	Enoyl-CoA hydratase
PD630_RS21735	COG0318	PFAM AMP-dependent synthetase and ligase
PD630_RS21765	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PD630_RS21795	COG1960	acyl-CoA dehydrogenase activity
PD630_RS21875	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS21910	COG0789	Transcriptional regulator
PD630_RS21915	COG1064	alcohol dehydrogenase
PD630_RS21980	COG1042	CoA-binding domain protein
PD630_RS21980	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PD630_RS21980	COG0045	succinate-CoA ligase (ADP-forming) activity
PD630_RS21985	COG1414	Transcriptional regulator
PD630_RS21995	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS22055	COG3842	ATPase activity
PD630_RS22065	COG1802	Transcriptional regulator
PD630_RS22080	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
PD630_RS22115	COG3842	ATPase activity
PD630_RS22125	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
PD630_RS22135	COG0395	ABC-type sugar transport system, permease component
PD630_RS22145	COG0583	DNA-binding transcription factor activity
PD630_RS22185	COG1012	belongs to the aldehyde dehydrogenase family
PD630_RS22195	COG1024	Enoyl-CoA hydratase
PD630_RS22205	COG1960	acyl-CoA dehydrogenase activity
PD630_RS22210	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PD630_RS22220	COG0583	DNA-binding transcription factor activity
PD630_RS22245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PD630_RS22255	COG2271	Major facilitator Superfamily
PD630_RS22265	COG1802	Transcriptional regulator
PD630_RS22285	COG1960	acyl-CoA dehydrogenase activity
PD630_RS22290	COG1960	acyl-CoA dehydrogenase activity
PD630_RS22300	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS22305	COG0183	Belongs to the thiolase family
PD630_RS22310	COG2130	NADP-dependent
PD630_RS22320	COG1063	alcohol dehydrogenase
PD630_RS22335	COG0318	PFAM AMP-dependent synthetase and ligase
PD630_RS22345	COG1278	Cold shock
PD630_RS22355	COG0667	Aldo Keto reductase
PD630_RS22365	COG0454	-acetyltransferase
PD630_RS22410	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
PD630_RS22435	COG0477	Major facilitator Superfamily
PD630_RS22440	COG2986	histidine ammonia-lyase
PD630_RS22465	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PD630_RS22490	COG3547	Transposase (IS116 IS110 IS902 family)
PD630_RS22555	COG2070	2-Nitropropane dioxygenase
PD630_RS22560	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PD630_RS22580	COG2271	Major facilitator Superfamily
PD630_RS22615	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS22625	COG0251	oxidation-reduction process
PD630_RS22635	COG0765	amino acid transport
PD630_RS22650	COG3835	regulator
PD630_RS22655	COG0477	Major facilitator Superfamily
PD630_RS22660	COG0583	DNA-binding transcription factor activity
PD630_RS22665	COG2070	2-Nitropropane dioxygenase
PD630_RS22670	COG0583	DNA-binding transcription factor activity
PD630_RS22680	COG1484	DNA-dependent DNA replication
PD630_RS22690	COG0582	viral genome integration into host DNA
PD630_RS22695	COG0582	viral genome integration into host DNA
PD630_RS22700	COG4974	Belongs to the 'phage' integrase family
PD630_RS22710	COG0477	Major facilitator Superfamily
PD630_RS22735	COG3958	Transketolase
PD630_RS22740	COG3959	Transketolase, thiamine diphosphate binding domain
PD630_RS22760	COG1129	ABC transporter
PD630_RS22765	COG1172	Belongs to the binding-protein-dependent transport system permease family
PD630_RS22780	COG2072	flavoprotein involved in K transport
PD630_RS22800	COG2241	protein methyltransferase activity
PD630_RS22800	COG2242	protein methyltransferase activity
PD630_RS22805	COG0300	oxidoreductase activity
PD630_RS22845	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PD630_RS22850	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PD630_RS22855	COG2378	regulation of single-species biofilm formation
PD630_RS22880	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
PD630_RS22940	COG0564	pseudouridine synthase activity
PD630_RS22945	COG1054	Belongs to the UPF0176 family
PD630_RS22950	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PD630_RS22955	COG1410	methionine synthase
PD630_RS22955	COG0646	methionine synthase
PD630_RS22970	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PD630_RS22975	COG2146	nitrite reductase [NAD(P)H] activity
PD630_RS22980	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
PD630_RS22980	COG2755	lipolytic protein G-D-S-L family
PD630_RS23040	COG0215	cysteine-tRNA ligase activity
PD630_RS23060	COG1968	undecaprenyl-diphosphatase activity
PD630_RS23065	COG0667	Aldo Keto reductase
PD630_RS23070	COG5398	heme oxygenase
PD630_RS23080	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PD630_RS23085	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
PD630_RS23115	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PD630_RS23140	COG3268	Saccharopine dehydrogenase
PD630_RS23145	COG0730	response to heat
PD630_RS23150	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
PD630_RS23160	COG1408	metallophosphoesterase
PD630_RS23185	COG1716	ATPase activity
PD630_RS23220	COG1051	belongs to the nudix hydrolase family
PD630_RS23225	COG0318	PFAM AMP-dependent synthetase and ligase
PD630_RS23255	COG1595	DNA-templated transcription, initiation
PD630_RS23260	COG1376	ErfK ybiS ycfS ynhG family protein
PD630_RS23270	COG1160	GTP binding
PD630_RS23275	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
PD630_RS23280	COG1187	pseudouridine synthase activity
PD630_RS23285	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PD630_RS23290	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PD630_RS23305	COG0494	nUDIX hydrolase
PD630_RS23310	COG0504	CTP synthase activity
PD630_RS23330	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PD630_RS23345	COG0647	UMP catabolic process
PD630_RS23370	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PD630_RS23375	COG2094	Belongs to the DNA glycosylase MPG family
PD630_RS23380	COG1131	(ABC) transporter
PD630_RS23390	COG1309	transcriptional regulator
PD630_RS23405	COG0165	Argininosuccinate lyase
PD630_RS23415	COG1438	arginine binding
PD630_RS23420	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PD630_RS23425	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PD630_RS23430	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
PD630_RS23435	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PD630_RS23440	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PD630_RS23450	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PD630_RS23450	COG0072	phenylalanine-tRNA ligase activity
PD630_RS23455	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PD630_RS23490	COG2378	regulation of single-species biofilm formation
PD630_RS23505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PD630_RS23545	COG0237	dephospho-CoA kinase activity
PD630_RS23545	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PD630_RS23555	COG0539	negative regulation of cytoplasmic translation
PD630_RS23560	COG2226	methyltransferase
PD630_RS23580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PD630_RS23585	COG0473	3-isopropylmalate dehydrogenase activity
PD630_RS23605	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PD630_RS23640	COG1309	transcriptional regulator
PD630_RS23660	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PD630_RS23665	COG1595	DNA-templated transcription, initiation
PD630_RS23690	COG1946	Acyl-CoA thioesterase
PD630_RS23710	COG0070	glutamate synthase
PD630_RS23710	COG0069	glutamate synthase activity
PD630_RS23710	COG0067	glutamate synthase
PD630_RS23720	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PD630_RS23725	COG0159	tryptophan synthase activity
PD630_RS23735	COG0134	indole-3-glycerol-phosphate synthase activity
PD630_RS23745	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PD630_RS23755	COG3384	dioxygenase
PD630_RS23770	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PD630_RS23775	COG0107	imidazoleglycerol-phosphate synthase activity
PD630_RS23780	COG0483	inositol monophosphate 1-phosphatase activity
PD630_RS23785	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PD630_RS23795	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PD630_RS23815	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PD630_RS23820	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PD630_RS23870	COG4221	oxidoreductase activity
PD630_RS23885	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
PD630_RS23915	COG1053	succinate dehydrogenase
PD630_RS23940	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
PD630_RS23945	COG0156	8-amino-7-oxononanoate synthase activity
PD630_RS23950	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PD630_RS23970	COG1309	transcriptional regulator
PD630_RS23985	COG0477	Major facilitator Superfamily
PD630_RS24000	COG0028	Belongs to the TPP enzyme family
PD630_RS24035	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PD630_RS24060	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PD630_RS24070	COG3599	regulation of cell shape
PD630_RS24080	COG1799	cell septum assembly
PD630_RS24095	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PD630_RS24100	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
PD630_RS24105	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PD630_RS24110	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PD630_RS24120	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PD630_RS24125	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PD630_RS24135	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PD630_RS24140	COG0768	penicillin binding
PD630_RS24150	COG0275	rRNA processing
PD630_RS24200	COG0142	geranyltranstransferase activity
PD630_RS24230	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
PD630_RS24250	COG1940	carbohydrate kinase activity
PD630_RS24260	COG0003	Pfam Anion-transporting ATPase
PD630_RS24310	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PD630_RS24320	COG1845	cytochrome c oxidase, subunit III
PD630_RS24335	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
PD630_RS24355	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
PD630_RS24365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PD630_RS24395	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
PD630_RS24400	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
PD630_RS24405	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PD630_RS24410	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PD630_RS24415	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PD630_RS24435	COG0321	lipoyl(octanoyl) transferase activity
PD630_RS24440	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PD630_RS24455	COG0174	glutamine synthetase
PD630_RS24465	COG2814	Major facilitator Superfamily
PD630_RS24475	COG1174	glycine betaine transport
PD630_RS24485	COG1174	glycine betaine transport
PD630_RS24500	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
PD630_RS24505	COG0174	glutamine synthetase
PD630_RS24515	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
PD630_RS24545	COG2030	dehydratase
PD630_RS24555	COG1280	lysine exporter protein (LysE YggA)
PD630_RS24610	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
PD630_RS24630	COG1510	regulation of RNA biosynthetic process
PD630_RS24675	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PD630_RS24750	COG0232	Belongs to the dGTPase family. Type 2 subfamily
PD630_RS24770	COG0423	glycine-tRNA ligase activity
PD630_RS24790	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PD630_RS24795	COG1381	Involved in DNA repair and RecF pathway recombination
PD630_RS24830	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
PD630_RS24835	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
PD630_RS24855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PD630_RS24905	COG0484	heat shock protein binding
PD630_RS24950	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PD630_RS24965	COG0028	Belongs to the TPP enzyme family
PD630_RS24990	COG4424	Sulfotransferase
PD630_RS24995	COG0175	sulfate reduction
PD630_RS25005	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PD630_RS25010	COG3119	arylsulfatase activity
PD630_RS25015	COG3842	ATPase activity
PD630_RS25020	COG4208	sulfate ABC transporter
PD630_RS25040	COG3387	PFAM Glycoside hydrolase 15-related
PD630_RS25045	COG2070	2-Nitropropane dioxygenase
PD630_RS25050	COG0481	GTPase activity
PD630_RS25065	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
PD630_RS25070	COG1305	Transglutaminase-like
PD630_RS25080	COG2308	Evidence 4 Homologs of previously reported genes of
PD630_RS25085	COG0268	Binds directly to 16S ribosomal RNA
PD630_RS25100	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
PD630_RS25105	COG2272	Belongs to the type-B carboxylesterase lipase family
PD630_RS25115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PD630_RS25135	COG2755	lipolytic protein G-D-S-L family
PD630_RS25140	COG0406	alpha-ribazole phosphatase activity
PD630_RS25145	COG0799	negative regulation of ribosome biogenesis
PD630_RS25150	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PD630_RS25160	COG0542	response to heat
PD630_RS25165	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PD630_RS25170	COG1902	pentaerythritol trinitrate reductase activity
PD630_RS25180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PD630_RS25185	COG0514	ATP-dependent DNA helicase (RecQ)
PD630_RS25190	COG0456	acetyltransferase
PD630_RS25195	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PD630_RS25205	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PD630_RS25215	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PD630_RS25230	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PD630_RS25235	COG0211	Belongs to the bacterial ribosomal protein bL27 family
PD630_RS25250	COG0105	UTP biosynthetic process
PD630_RS25260	COG0285	dihydrofolate synthase activity
PD630_RS25265	COG0525	valine-tRNA ligase activity
PD630_RS25270	COG0525	valine-tRNA ligase activity
PD630_RS25280	COG3835	regulator
PD630_RS25290	COG0251	oxidation-reduction process
PD630_RS25295	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PD630_RS25335	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
PD630_RS25350	COG3485	protocatechuate 3,4-dioxygenase
PD630_RS25355	COG3485	protocatechuate 3,4-dioxygenase
PD630_RS25365	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PD630_RS25370	COG1414	Transcriptional regulator
PD630_RS25375	COG0183	Belongs to the thiolase family
PD630_RS25380	COG2986	histidine ammonia-lyase
PD630_RS25400	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PD630_RS25405	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PD630_RS25410	COG1309	transcriptional regulator
PD630_RS25425	COG1172	Belongs to the binding-protein-dependent transport system permease family
PD630_RS25435	COG0477	Major facilitator Superfamily
PD630_RS25440	COG2188	Transcriptional regulator
PD630_RS25445	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PD630_RS25455	COG3718	enzyme involved in inositol metabolism
PD630_RS25460	COG3962	Belongs to the TPP enzyme family
PD630_RS25470	COG0673	inositol 2-dehydrogenase activity
PD630_RS25475	COG1082	Xylose isomerase domain protein TIM barrel
PD630_RS25485	COG1252	NADH dehydrogenase
PD630_RS25490	COG1940	carbohydrate kinase activity
PD630_RS25495	COG2814	Major facilitator Superfamily
PD630_RS25500	COG1609	Transcriptional regulator
PD630_RS25520	COG1082	Xylose isomerase domain protein TIM barrel
PD630_RS25520	COG3185	4-Hydroxyphenylpyruvate dioxygenase
PD630_RS25525	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
PD630_RS25535	COG0740	serine-type endopeptidase activity
PD630_RS25540	COG0740	serine-type endopeptidase activity
PD630_RS25545	COG0544	peptidyl-prolyl cis-trans isomerase activity
PD630_RS25580	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
PD630_RS25595	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PD630_RS25610	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
PD630_RS25625	COG2346	COG2346, Truncated hemoglobins
PD630_RS25630	COG0366	Alpha amylase catalytic
PD630_RS25645	COG0824	Thioesterase
PD630_RS25650	COG2902	Dehydrogenase
PD630_RS25655	COG0824	Thioesterase
PD630_RS25700	COG0300	oxidoreductase activity
PD630_RS25710	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
PD630_RS25740	COG0596	Alpha beta hydrolase
PD630_RS25750	COG2270	Major facilitator Superfamily
PD630_RS25760	COG0446	pyridine nucleotide-disulphide oxidoreductase
PD630_RS25760	COG1902	pentaerythritol trinitrate reductase activity
PD630_RS25765	COG0300	oxidoreductase activity
PD630_RS25770	COG0433	COG0433 Predicted ATPase
PD630_RS25775	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
PD630_RS25785	COG1376	ErfK ybiS ycfS ynhG family protein
PD630_RS25805	COG1309	transcriptional regulator
PD630_RS25825	COG0736	holo-[acyl-carrier-protein] synthase activity
PD630_RS25855	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PD630_RS25860	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
PD630_RS25865	COG1234	tRNA 3'-trailer cleavage
PD630_RS25895	COG3191	aminopeptidase activity
PD630_RS25905	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
PD630_RS25910	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PD630_RS25915	COG1335	isochorismatase
PD630_RS25925	COG1131	(ABC) transporter
PD630_RS25935	COG0058	SHG alpha-glucan phosphorylase activity
PD630_RS25940	COG0366	Alpha amylase catalytic
PD630_RS25945	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PD630_RS25955	COG1414	Transcriptional regulator
PD630_RS25960	COG3734	2-keto-3-deoxy-galactonokinase
PD630_RS25965	COG0800	Aldolase
PD630_RS25970	COG4948	Mandelate Racemase Muconate Lactonizing
PD630_RS25975	COG2271	Major facilitator Superfamily
PD630_RS25985	COG2409	Drug exporters of the RND superfamily
PD630_RS25990	COG0183	Belongs to the thiolase family
PD630_RS25995	COG0346	lactoylglutathione lyase activity
PD630_RS26010	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
PD630_RS26060	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PD630_RS26075	COG0355	proton-transporting ATP synthase activity, rotational mechanism
PD630_RS26080	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PD630_RS26085	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PD630_RS26090	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PD630_RS26095	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PD630_RS26100	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PD630_RS26105	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PD630_RS26110	COG0356	it plays a direct role in the translocation of protons across the membrane
PD630_RS26130	COG2890	protein-(glutamine-N5) methyltransferase activity
PD630_RS26135	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PD630_RS26140	COG0254	rRNA binding
PD630_RS26145	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PD630_RS26145	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PD630_RS26155	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
PD630_RS26160	COG0460	homoserine dehydrogenase
PD630_RS26165	COG0019	diaminopimelate decarboxylase activity
PD630_RS26170	COG0018	arginyl-trna synthetase
PD630_RS26185	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
PD630_RS26195	COG0686	Belongs to the AlaDH PNT family
PD630_RS26200	COG0318	PFAM AMP-dependent synthetase and ligase
PD630_RS26215	COG1960	acyl-CoA dehydrogenase activity
PD630_RS26220	COG1960	acyl-CoA dehydrogenase activity
PD630_RS26245	COG1024	Enoyl-CoA hydratase
PD630_RS26260	COG0318	PFAM AMP-dependent synthetase and ligase
PD630_RS26265	COG2130	NADP-dependent
PD630_RS26275	COG0477	Major facilitator Superfamily
PD630_RS26310	COG1218	3'(2'),5'-bisphosphate nucleotidase
PD630_RS26345	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PD630_RS26350	COG0740	serine-type endopeptidase activity
PD630_RS26355	COG0740	serine-type endopeptidase activity
PD630_RS26375	COG0596	Alpha beta hydrolase
PD630_RS26400	COG0318	PFAM AMP-dependent synthetase and ligase
PD630_RS26405	COG0477	Major facilitator Superfamily
PD630_RS26415	COG2814	Major facilitator Superfamily
PD630_RS26435	COG1024	Enoyl-CoA hydratase
PD630_RS26465	COG3142	Participates in the control of copper homeostasis
PD630_RS26470	COG0363	glucosamine-6-phosphate deaminase activity
PD630_RS26475	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
PD630_RS26480	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PD630_RS26490	COG1263	PTS System
PD630_RS26495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PD630_RS26510	COG4762	Protein conserved in bacteria
PD630_RS26520	COG0277	FAD linked oxidase domain protein
PD630_RS26525	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
PD630_RS26525	COG1672	PFAM Archaeal ATPase
PD630_RS26530	COG4279	zinc finger
PD630_RS26535	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PD630_RS26540	COG3321	synthase
PD630_RS26540	COG0604	alcohol dehydrogenase
PD630_RS26560	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PD630_RS26585	COG2233	PERMEase
PD630_RS26595	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
PD630_RS26600	COG3135	benzoate transporter
PD630_RS26625	COG0022	dehydrogenase e1 component
PD630_RS26630	COG0508	dehydrogenase complex catalyzes the overall conversion of
PD630_RS26635	COG0738	Major facilitator superfamily
PD630_RS26665	COG0318	PFAM AMP-dependent synthetase and ligase
PD630_RS26685	COG0277	FAD linked oxidase domain protein
PD630_RS26715	COG2272	Belongs to the type-B carboxylesterase lipase family
PD630_RS26725	COG0352	thiamine-phosphate diphosphorylase activity
PD630_RS26725	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
PD630_RS26725	COG0351	phosphomethylpyrimidine kinase
PD630_RS26730	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PD630_RS26735	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PD630_RS26750	COG0657	acetylesterase activity
PD630_RS26760	COG1053	succinate dehydrogenase
PD630_RS26795	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
PD630_RS26805	COG3800	Transcriptional regulator
PD630_RS26805	COG1396	sequence-specific DNA binding
PD630_RS26820	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
PD630_RS26825	COG0604	alcohol dehydrogenase
PD630_RS26825	COG3321	synthase
PD630_RS26830	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PD630_RS26835	COG0477	Major facilitator Superfamily
PD630_RS26850	COG0183	Belongs to the thiolase family
PD630_RS26900	COG1063	alcohol dehydrogenase
PD630_RS26910	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
PD630_RS26930	COG1053	succinate dehydrogenase
PD630_RS26940	COG0277	FAD linked oxidase domain protein
PD630_RS26940	COG0247	lactate metabolic process
PD630_RS26955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PD630_RS26960	COG1793	dna ligase
PD630_RS26975	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS26980	COG2020	methyltransferase activity
PD630_RS26985	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PD630_RS27030	COG2326	polyphosphate kinase activity
PD630_RS27045	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
PD630_RS27050	COG0330	HflC and HflK could
PD630_RS27105	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PD630_RS27170	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PD630_RS27190	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
PD630_RS27215	COG1100	Small GTP-binding protein
PD630_RS27275	COG1832	CoA-binding protein
PD630_RS27305	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PD630_RS27320	COG2197	response regulator
PD630_RS27325	COG4585	Histidine kinase
PD630_RS27355	COG3012	SEC-C Motif Domain Protein
PD630_RS27360	COG0515	serine threonine protein kinase
PD630_RS27380	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PD630_RS27380	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PD630_RS27420	COG2030	dehydratase
PD630_RS27445	COG0174	glutamine synthetase
PD630_RS27480	COG2175	clavaminate synthase activity
PD630_RS27485	COG1414	Transcriptional regulator
PD630_RS27505	COG0747	negative chemotaxis
PD630_RS27515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PD630_RS27520	COG0601	transmembrane transport
PD630_RS27535	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PD630_RS27545	COG1464	Belongs to the NlpA lipoprotein family
PD630_RS27555	COG1733	regulation of RNA biosynthetic process
PD630_RS27560	COG0604	alcohol dehydrogenase
PD630_RS27560	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS27560	COG3321	synthase
PD630_RS27575	COG3795	YCII-related domain
PD630_RS27590	COG0431	NADPH-dependent FMN reductase
PD630_RS27600	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PD630_RS27605	COG2011	ABC-type metal ion transport system permease component
PD630_RS27610	COG4608	Belongs to the ABC transporter superfamily
PD630_RS27620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PD630_RS27625	COG0601	transmembrane transport
PD630_RS27635	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PD630_RS27660	COG1231	oxidoreductase activity
PD630_RS27695	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
PD630_RS27700	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
PD630_RS27700	COG1473	amidohydrolase
PD630_RS27710	COG0251	oxidation-reduction process
PD630_RS27715	COG2368	4-hydroxyphenylacetate
PD630_RS27720	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PD630_RS27740	COG0583	DNA-binding transcription factor activity
PD630_RS27745	COG0531	amino acid
PD630_RS27760	COG1012	belongs to the aldehyde dehydrogenase family
PD630_RS27775	COG1823	symporter activity
PD630_RS27785	COG0067	glutamate synthase
PD630_RS27785	COG0069	glutamate synthase activity
PD630_RS27785	COG0070	glutamate synthase
PD630_RS27790	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PD630_RS27810	COG3483	tryptophan 2,3-dioxygenase activity
PD630_RS27815	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PD630_RS27840	COG1012	belongs to the aldehyde dehydrogenase family
PD630_RS27845	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PD630_RS27850	COG4638	Rieske (2fe-2S)
PD630_RS27855	COG1414	Transcriptional regulator
PD630_RS27860	COG2146	nitrite reductase [NAD(P)H] activity
PD630_RS27890	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PD630_RS27900	COG1802	Transcriptional regulator
PD630_RS27905	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PD630_RS27930	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PD630_RS27960	COG1414	Transcriptional regulator
PD630_RS27970	COG0477	Major facilitator Superfamily
PD630_RS27985	COG0726	polysaccharide deacetylase
PD630_RS28020	COG1074	ATP-dependent DNA helicase activity
PD630_RS28065	COG2376	Dihydroxyacetone kinase
PD630_RS28070	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PD630_RS28075	COG0477	Major facilitator Superfamily
PD630_RS28090	COG1053	succinate dehydrogenase
PD630_RS28095	COG0673	inositol 2-dehydrogenase activity
PD630_RS28100	COG0656	L-ascorbic acid biosynthetic process
PD630_RS28110	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PD630_RS28115	COG0477	Major facilitator Superfamily
PD630_RS28120	COG0583	DNA-binding transcription factor activity
PD630_RS28125	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS28135	COG0179	Fumarylacetoacetate (FAA) hydrolase
PD630_RS28150	COG2814	Major facilitator Superfamily
PD630_RS28155	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PD630_RS28165	COG0069	glutamate synthase activity
PD630_RS28180	COG2072	flavoprotein involved in K transport
PD630_RS28190	COG0183	Belongs to the thiolase family
PD630_RS28210	COG1012	belongs to the aldehyde dehydrogenase family
PD630_RS28215	COG0667	Aldo Keto reductase
PD630_RS28220	COG2365	Tyrosine phosphatase family
PD630_RS28290	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
PD630_RS28295	COG0659	secondary active sulfate transmembrane transporter activity
PD630_RS28300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PD630_RS28305	COG0765	amino acid transport
PD630_RS28310	COG1126	abc transporter atp-binding protein
PD630_RS28365	COG0714	Associated with various cellular activities
PD630_RS28370	COG2425	protein containing a von Willebrand factor type A (vWA) domain
PD630_RS28375	COG3552	Protein containing von Willebrand factor type A (VWA) domain
PD630_RS28390	COG1960	acyl-CoA dehydrogenase activity
PD630_RS28410	COG1302	Protein conserved in bacteria
PD630_RS28445	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PD630_RS28450	COG0049	tRNA binding
PD630_RS28475	COG1024	Enoyl-CoA hydratase
PD630_RS28490	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PD630_RS28495	COG1960	acyl-CoA dehydrogenase activity
PD630_RS28510	COG4221	oxidoreductase activity
PD630_RS28515	COG1024	Enoyl-CoA hydratase
PD630_RS28520	COG5006	permease, DMT superfamily
PD630_RS28530	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PD630_RS28580	COG0477	Major facilitator Superfamily
PD630_RS28610	COG0667	Aldo Keto reductase
PD630_RS28635	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PD630_RS28640	COG0085	RNA polymerase activity
PD630_RS28690	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PD630_RS28695	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PD630_RS28720	COG0477	Major facilitator Superfamily
PD630_RS28725	COG0081	regulation of translation
PD630_RS28750	COG2030	dehydratase
PD630_RS28755	COG2030	dehydratase
PD630_RS28760	COG0267	Belongs to the bacterial ribosomal protein bL33 family
PD630_RS28780	COG1666	GTP binding
PD630_RS28785	COG0501	Belongs to the peptidase M48B family
PD630_RS28790	COG0142	geranyltranstransferase activity
PD630_RS28800	COG2226	methyltransferase
PD630_RS28805	COG1012	belongs to the aldehyde dehydrogenase family
PD630_RS28810	COG0438	transferase activity, transferring glycosyl groups
PD630_RS28820	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
PD630_RS28825	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PD630_RS28830	COG2375	cellular response to nickel ion
PD630_RS28840	COG4948	Mandelate Racemase Muconate Lactonizing
PD630_RS28945	COG1950	PFAM Membrane protein of
PD630_RS28970	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PD630_RS28995	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PD630_RS29000	COG1333	cytochrome c biogenesis protein
PD630_RS29005	COG0785	Cytochrome C biogenesis protein
PD630_RS29015	COG0406	alpha-ribazole phosphatase activity
PD630_RS29020	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
PD630_RS29035	COG3185	4-Hydroxyphenylpyruvate dioxygenase
PD630_RS29040	COG1522	sequence-specific DNA binding
PD630_RS29100	COG0181	hydroxymethylbilane synthase activity
PD630_RS29110	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PD630_RS29180	COG0745	RESPONSE REGULATOR receiver
PD630_RS29185	COG5002	protein histidine kinase activity
PD630_RS29190	COG0588	phosphoglycerate mutase activity
PD630_RS29195	COG0318	PFAM AMP-dependent synthetase and ligase
PD630_RS29205	COG0438	transferase activity, transferring glycosyl groups
PD630_RS29220	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
PD630_RS29235	COG1335	isochorismatase
PD630_RS29255	COG0477	Major facilitator Superfamily
PD630_RS29275	COG0812	UDP-N-acetylmuramate dehydrogenase activity
PD630_RS29310	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PD630_RS29315	COG2226	methyltransferase
PD630_RS29335	COG2271	Major facilitator Superfamily
PD630_RS29340	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PD630_RS29345	COG2267	carboxylic ester hydrolase activity
PD630_RS29350	COG0789	Transcriptional regulator
PD630_RS29370	COG2733	membrane
PD630_RS29390	COG2326	polyphosphate kinase activity
PD630_RS29405	COG0297	glycogen (starch) synthase activity
PD630_RS29430	COG1064	alcohol dehydrogenase
PD630_RS29435	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PD630_RS29445	COG2224	Isocitrate lyase
PD630_RS29490	COG1802	Transcriptional regulator
PD630_RS29505	COG2031	fatty acid transporter
PD630_RS29520	COG0702	epimerase
PD630_RS29525	COG1733	regulation of RNA biosynthetic process
PD630_RS29540	COG1505	serine-type exopeptidase activity
PD630_RS29565	COG1983	PspC domain protein
PD630_RS29575	COG0459	protein refolding
PD630_RS29590	COG0589	response to stress
PD630_RS29600	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
PD630_RS29600	COG2508	Transcriptional regulator
PD630_RS29605	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PD630_RS29615	COG2986	histidine ammonia-lyase
PD630_RS29635	COG0688	phosphatidylethanolamine metabolic process
PD630_RS29645	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PD630_RS29650	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
PD630_RS29665	COG2111	Na H antiporter
PD630_RS29665	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
PD630_RS29670	COG1006	Multisubunit Na H antiporter MnhC subunit
PD630_RS29675	COG0651	ATP synthesis coupled electron transport
PD630_RS29700	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
PD630_RS29745	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
PD630_RS29750	COG0351	phosphomethylpyrimidine kinase
PD630_RS29760	COG2234	aminopeptidase activity
PD630_RS29770	COG1131	(ABC) transporter
PD630_RS29775	COG2022	thiamine diphosphate biosynthetic process
PD630_RS29790	COG0352	thiamine-phosphate diphosphorylase activity
PD630_RS29805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PD630_RS29815	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PD630_RS29850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PD630_RS29880	COG1250	3-hydroxyacyl-CoA dehydrogenase
PD630_RS29905	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PD630_RS29910	COG1960	acyl-CoA dehydrogenase activity
PD630_RS29920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PD630_RS29935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PD630_RS29940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PD630_RS29950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PD630_RS29960	COG0747	negative chemotaxis
PD630_RS29965	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PD630_RS29970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PD630_RS29985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PD630_RS29990	COG1126	abc transporter atp-binding protein
PD630_RS30030	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PD630_RS30065	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PD630_RS30070	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
PD630_RS30080	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PD630_RS30135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PD630_RS30145	COG1959	2 iron, 2 sulfur cluster binding
PD630_RS30150	COG1017	nitric oxide dioxygenase activity
PD630_RS30150	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PD630_RS30170	COG1113	amino acid transport
PD630_RS30200	COG0328	RNA-DNA hybrid ribonuclease activity
PD630_RS30210	COG0310	cobalt ion transport
PD630_RS30225	COG1122	ATPase activity
PD630_RS30245	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PD630_RS30250	COG0640	Transcriptional regulator
PD630_RS30255	COG0318	PFAM AMP-dependent synthetase and ligase
PD630_RS30260	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PD630_RS30265	COG1024	Enoyl-CoA hydratase
PD630_RS30275	COG0583	DNA-binding transcription factor activity
PD630_RS30285	COG1024	Enoyl-CoA hydratase
PD630_RS30310	COG0183	Belongs to the thiolase family
PD630_RS30315	COG2271	Major facilitator Superfamily
PD630_RS30325	COG4106	trans-aconitate 2-methyltransferase activity
PD630_RS30345	COG0477	Major facilitator Superfamily
PD630_RS30355	COG1960	acyl-CoA dehydrogenase activity
PD630_RS30360	COG1609	Transcriptional regulator
PD630_RS30365	COG0318	PFAM AMP-dependent synthetase and ligase
PD630_RS30375	COG1024	Enoyl-CoA hydratase
PD630_RS30405	COG1053	succinate dehydrogenase
PD630_RS30415	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS30425	COG1414	Transcriptional regulator
PD630_RS30455	COG1535	isochorismatase
PD630_RS30455	COG3433	isochorismatase activity
PD630_RS30460	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PD630_RS30470	COG0477	Major facilitator Superfamily
PD630_RS30495	COG2409	Drug exporters of the RND superfamily
PD630_RS30500	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
PD630_RS30515	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PD630_RS30520	COG1595	DNA-templated transcription, initiation
PD630_RS30550	COG3226	Transcriptional regulator
PD630_RS30575	COG1960	acyl-CoA dehydrogenase activity
PD630_RS30580	COG4221	oxidoreductase activity
PD630_RS30590	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS30595	COG1960	acyl-CoA dehydrogenase activity
PD630_RS30645	COG2124	cytochrome p450
PD630_RS30655	COG2267	carboxylic ester hydrolase activity
PD630_RS30660	COG1305	Transglutaminase-like
PD630_RS30675	COG0657	acetylesterase activity
PD630_RS30680	COG3265	gluconokinase activity
PD630_RS30695	COG0477	Major facilitator Superfamily
PD630_RS30700	COG1940	carbohydrate kinase activity
PD630_RS30705	COG0800	Aldolase
PD630_RS30710	COG0129	dihydroxy-acid dehydratase activity
PD630_RS30715	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PD630_RS30725	COG4829	muconolactone delta-isomerase
PD630_RS30730	COG4948	Mandelate Racemase Muconate Lactonizing
PD630_RS30735	COG3485	protocatechuate 3,4-dioxygenase
PD630_RS30740	COG1414	Transcriptional regulator
PD630_RS30745	COG3485	protocatechuate 3,4-dioxygenase
PD630_RS30755	COG2132	Multicopper oxidase
PD630_RS30765	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PD630_RS30790	COG4638	Rieske (2fe-2S)
PD630_RS30795	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
PD630_RS30810	COG2814	Major facilitator Superfamily
PD630_RS30815	COG1013	pyruvate-flavodoxin oxidoreductase activity
PD630_RS30820	COG0674	pyruvate-flavodoxin oxidoreductase activity
PD630_RS30820	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
PD630_RS30850	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
PD630_RS30865	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PD630_RS30915	COG1012	belongs to the aldehyde dehydrogenase family
PD630_RS30925	COG1172	Belongs to the binding-protein-dependent transport system permease family
PD630_RS30930	COG1129	ABC transporter
PD630_RS30935	COG1172	Belongs to the binding-protein-dependent transport system permease family
PD630_RS30940	COG1879	ABC-type sugar transport system periplasmic component
PD630_RS30945	COG1929	Belongs to the glycerate kinase type-1 family
PD630_RS30950	COG0656	L-ascorbic acid biosynthetic process
PD630_RS30960	COG1960	acyl-CoA dehydrogenase activity
PD630_RS30965	COG4670	ketone body catabolic process
PD630_RS30980	COG3185	4-Hydroxyphenylpyruvate dioxygenase
PD630_RS30980	COG1082	Xylose isomerase domain protein TIM barrel
PD630_RS30985	COG1609	Transcriptional regulator
PD630_RS30990	COG1063	alcohol dehydrogenase
PD630_RS31060	COG0477	Major facilitator Superfamily
PD630_RS31065	COG1309	transcriptional regulator
PD630_RS31095	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PD630_RS31110	COG2814	Major facilitator Superfamily
PD630_RS31175	COG0640	Transcriptional regulator
PD630_RS31225	COG1358	cellular component organization or biogenesis
PD630_RS31280	COG3467	pyridoxamine 5'-phosphate
PD630_RS31290	COG0251	oxidation-reduction process
PD630_RS31295	COG1414	Transcriptional regulator
PD630_RS31310	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
PD630_RS31320	COG2610	gluconate transmembrane transporter activity
PD630_RS31335	COG2133	pyrroloquinoline quinone binding
PD630_RS31350	COG1414	Transcriptional regulator
PD630_RS31355	COG0477	Major facilitator Superfamily
PD630_RS31360	COG1113	amino acid transport
PD630_RS31375	COG2175	clavaminate synthase activity
PD630_RS31390	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS31405	COG1053	succinate dehydrogenase
PD630_RS31410	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PD630_RS31415	COG1695	Transcriptional regulator
PD630_RS31420	COG0657	acetylesterase activity
PD630_RS31425	COG1414	Transcriptional regulator
PD630_RS31430	COG0346	lactoylglutathione lyase activity
PD630_RS31450	COG2072	flavoprotein involved in K transport
PD630_RS31460	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PD630_RS31470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PD630_RS31480	COG1012	belongs to the aldehyde dehydrogenase family
PD630_RS31485	COG3284	Transcriptional regulator
PD630_RS31500	COG1473	amidohydrolase
PD630_RS31510	COG2318	DinB family
PD630_RS31565	COG3485	protocatechuate 3,4-dioxygenase
PD630_RS31580	COG0318	PFAM AMP-dependent synthetase and ligase
PD630_RS31600	COG1309	transcriptional regulator
PD630_RS31615	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PD630_RS31625	COG1309	transcriptional regulator
PD630_RS31635	COG0546	phosphoglycolate phosphatase activity
PD630_RS31650	COG3239	Fatty acid desaturase
PD630_RS31685	COG2755	lipolytic protein G-D-S-L family
PD630_RS31685	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
PD630_RS31690	COG2814	Major facilitator Superfamily
PD630_RS31705	COG1121	(ABC) transporter
PD630_RS31710	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PD630_RS31720	COG0803	Belongs to the bacterial solute-binding protein 9 family
PD630_RS31740	COG0156	8-amino-7-oxononanoate synthase activity
PD630_RS31760	COG0702	epimerase
PD630_RS31790	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PD630_RS31795	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PD630_RS31810	COG5343	regulation of RNA biosynthetic process
PD630_RS31815	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
PD630_RS31825	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
PD630_RS31835	COG1953	Uracil, thiamine, allantoin
PD630_RS31845	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
PD630_RS31855	COG4266	Belongs to the allantoicase family
PD630_RS31860	COG1929	Belongs to the glycerate kinase type-1 family
PD630_RS31865	COG3960	tartronate-semialdehyde synthase activity
PD630_RS31870	COG2084	Dehydrogenase
PD630_RS31875	COG3622	Belongs to the hyi family
PD630_RS31885	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
PD630_RS31890	COG1301	dicarboxylic acid transport
PD630_RS31895	COG1414	Transcriptional regulator
PD630_RS31910	COG2771	luxR family
PD630_RS31915	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
PD630_RS31935	COG2986	histidine ammonia-lyase
PD630_RS31940	COG0517	IMP dehydrogenase activity
PD630_RS31940	COG1125	glycine betaine transport
PD630_RS32045	COG1012	belongs to the aldehyde dehydrogenase family
PD630_RS32085	COG1695	Transcriptional regulator
PD630_RS32090	COG0242	peptide deformylase activity
PD630_RS32110	COG2197	response regulator
PD630_RS32115	COG4585	Histidine kinase
PD630_RS32145	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS32150	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PD630_RS32155	COG1960	acyl-CoA dehydrogenase activity
PD630_RS32165	COG3246	L-lysine catabolic process to acetate
PD630_RS32170	COG2814	Major facilitator Superfamily
PD630_RS32195	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS32240	COG0318	PFAM AMP-dependent synthetase and ligase
PD630_RS32245	COG4770	biotin carboxylase activity
PD630_RS32250	COG0604	alcohol dehydrogenase
PD630_RS32255	COG1063	alcohol dehydrogenase
PD630_RS32265	COG0800	Aldolase
PD630_RS32270	COG0477	Major facilitator Superfamily
PD630_RS32275	COG0246	Mannitol dehydrogenase
PD630_RS32280	COG4948	Mandelate Racemase Muconate Lactonizing
PD630_RS32285	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PD630_RS32295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PD630_RS32300	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
PD630_RS32315	COG2814	Major facilitator Superfamily
PD630_RS32335	COG0477	Major facilitator Superfamily
PD630_RS32345	COG1376	ErfK ybiS ycfS ynhG family protein
PD630_RS32355	COG0604	alcohol dehydrogenase
PD630_RS32375	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS32395	COG1960	acyl-CoA dehydrogenase activity
PD630_RS32400	COG2223	nitrite transmembrane transporter activity
PD630_RS32410	COG1309	transcriptional regulator
PD630_RS32420	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PD630_RS32425	COG1960	acyl-CoA dehydrogenase activity
PD630_RS32430	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS32440	COG0318	PFAM AMP-dependent synthetase and ligase
PD630_RS32445	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS32450	COG0477	Major facilitator Superfamily
PD630_RS32495	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PD630_RS32500	COG1024	Enoyl-CoA hydratase
PD630_RS32505	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PD630_RS32515	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PD630_RS32520	COG0427	acetyl-CoA hydrolase
PD630_RS32525	COG0183	Belongs to the thiolase family
PD630_RS32530	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS32540	COG1960	acyl-CoA dehydrogenase activity
PD630_RS32545	COG2186	Transcriptional regulator
PD630_RS32550	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PD630_RS32555	COG1960	acyl-CoA dehydrogenase activity
PD630_RS32570	COG0318	PFAM AMP-dependent synthetase and ligase
PD630_RS32575	COG1024	Enoyl-CoA hydratase
PD630_RS32585	COG2197	response regulator
PD630_RS32590	COG0633	Ferredoxin
PD630_RS32600	COG0446	pyridine nucleotide-disulphide oxidoreductase
PD630_RS32630	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PD630_RS32650	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS32655	COG3547	Transposase (IS116 IS110 IS902 family)
PD630_RS32660	COG0318	PFAM AMP-dependent synthetase and ligase
PD630_RS32665	COG3842	ATPase activity
PD630_RS32670	COG0395	ABC-type sugar transport system, permease component
PD630_RS32675	COG1175	transmembrane transport
PD630_RS32690	COG1063	alcohol dehydrogenase
PD630_RS32705	COG1070	Carbohydrate kinase
PD630_RS32710	COG2130	NADP-dependent
PD630_RS32720	COG1309	transcriptional regulator
PD630_RS32730	COG0069	glutamate synthase activity
PD630_RS32735	COG2218	PFAM glutamate synthase alpha subunit domain protein
PD630_RS32740	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PD630_RS32750	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PD630_RS32805	COG1012	belongs to the aldehyde dehydrogenase family
PD630_RS32850	COG4191	Histidine kinase
PD630_RS32870	COG4638	Rieske (2fe-2S)
PD630_RS32880	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS32905	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PD630_RS32910	COG0154	amidase activity
PD630_RS32930	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PD630_RS32935	COG2151	metal-sulfur cluster biosynthetic enzyme
PD630_RS32940	COG3396	Phenylacetate-CoA oxygenase
PD630_RS32945	COG3460	Phenylacetate-CoA oxygenase
PD630_RS32950	COG3396	Phenylacetate-CoA oxygenase
PD630_RS32960	COG1250	3-hydroxyacyl-CoA dehydrogenase
PD630_RS32965	COG1024	Enoyl-CoA hydratase
PD630_RS32970	COG0183	Belongs to the thiolase family
PD630_RS32975	COG2030	dehydratase
PD630_RS32975	COG1012	belongs to the aldehyde dehydrogenase family
PD630_RS32985	COG2050	protein possibly involved in aromatic compounds catabolism
PD630_RS32995	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
PD630_RS33000	COG2188	Transcriptional regulator
PD630_RS33010	COG2301	Belongs to the HpcH HpaI aldolase family
PD630_RS33020	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PD630_RS33035	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PD630_RS33065	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PD630_RS33085	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PD630_RS33100	COG1942	4-Oxalocrotonate Tautomerase
PD630_RS33105	COG2079	MmgE PrpD family protein
PD630_RS33140	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PD630_RS33145	COG0583	DNA-binding transcription factor activity
PD630_RS33155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PD630_RS33160	COG2814	Major facilitator Superfamily
PD630_RS33165	COG0789	Transcriptional regulator
PD630_RS33175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PD630_RS33185	COG2814	Major facilitator Superfamily
PD630_RS33190	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS33200	COG1172	Belongs to the binding-protein-dependent transport system permease family
PD630_RS33205	COG1129	ABC transporter
PD630_RS33220	COG1902	pentaerythritol trinitrate reductase activity
PD630_RS33230	COG2197	response regulator
PD630_RS33240	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PD630_RS33260	COG0179	Fumarylacetoacetate (FAA) hydrolase
PD630_RS33270	COG1129	ABC transporter
PD630_RS33275	COG1172	Belongs to the binding-protein-dependent transport system permease family
PD630_RS33305	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS33315	COG1012	belongs to the aldehyde dehydrogenase family
PD630_RS33320	COG1902	pentaerythritol trinitrate reductase activity
PD630_RS33330	COG1960	acyl-CoA dehydrogenase activity
PD630_RS33340	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PD630_RS33350	COG1946	Acyl-CoA thioesterase
PD630_RS33355	COG4770	biotin carboxylase activity
PD630_RS33365	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PD630_RS33385	COG1309	transcriptional regulator
PD630_RS33405	COG0477	Major facilitator Superfamily
PD630_RS33410	COG0583	DNA-binding transcription factor activity
PD630_RS33445	COG2271	Major facilitator Superfamily
PD630_RS33460	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PD630_RS33465	COG1115	amino acid carrier protein
PD630_RS33510	COG2271	Major facilitator Superfamily
PD630_RS33520	COG1802	Transcriptional regulator
PD630_RS33525	COG2271	Major facilitator Superfamily
PD630_RS33545	COG1053	succinate dehydrogenase
PD630_RS33550	COG1414	Transcriptional regulator
PD630_RS33555	COG0477	Major facilitator Superfamily
PD630_RS33570	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS33580	COG1295	ribonuclease BN
PD630_RS33590	COG2814	Major facilitator Superfamily
PD630_RS33610	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PD630_RS33615	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PD630_RS33620	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PD630_RS33620	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PD630_RS33625	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PD630_RS33630	COG0509	glycine decarboxylation via glycine cleavage system
PD630_RS33660	COG2186	Transcriptional regulator
PD630_RS33665	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PD630_RS33670	COG1960	acyl-CoA dehydrogenase activity
PD630_RS33675	COG0477	Major facilitator Superfamily
PD630_RS33680	COG0583	DNA-binding transcription factor activity
PD630_RS33690	COG1569	PIN domain
PD630_RS33695	COG3311	Transcriptional regulator
PD630_RS33710	COG1027	Aspartate ammonia-lyase
PD630_RS33715	COG1301	dicarboxylic acid transport
PD630_RS33725	COG2124	cytochrome p450
PD630_RS33735	COG1414	Transcriptional regulator
PD630_RS33740	COG3559	Exporter of polyketide antibiotics
PD630_RS33745	COG1131	(ABC) transporter
PD630_RS33750	COG1309	transcriptional regulator
PD630_RS33815	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PD630_RS33830	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
PD630_RS33835	COG4948	Mandelate Racemase Muconate Lactonizing
PD630_RS33840	COG1509	lysine 2,3-aminomutase activity
PD630_RS33855	COG2814	Major facilitator Superfamily
PD630_RS33870	COG1414	Transcriptional regulator
PD630_RS33890	COG4638	Rieske (2fe-2S)
PD630_RS33905	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PD630_RS33910	COG0154	amidase activity
PD630_RS33915	COG0471	metal ion transport
PD630_RS33925	COG1113	amino acid transport
PD630_RS33965	COG0583	DNA-binding transcription factor activity
PD630_RS33990	COG2814	Major facilitator Superfamily
PD630_RS33995	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PD630_RS34000	COG1024	Enoyl-CoA hydratase
PD630_RS34005	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
PD630_RS34010	COG3386	PFAM SMP-30 Gluconolaconase
PD630_RS34015	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS34025	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PD630_RS34030	COG1960	acyl-CoA dehydrogenase activity
PD630_RS34050	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PD630_RS34055	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PD630_RS34085	COG1846	Transcriptional regulator
PD630_RS34090	COG0477	Major facilitator Superfamily
PD630_RS34095	COG0183	Belongs to the thiolase family
PD630_RS34105	COG0183	Belongs to the thiolase family
PD630_RS34110	COG1960	acyl-CoA dehydrogenase activity
PD630_RS34120	COG1960	acyl-CoA dehydrogenase activity
PD630_RS34130	COG0583	DNA-binding transcription factor activity
PD630_RS34135	COG0583	DNA-binding transcription factor activity
PD630_RS34145	COG1012	belongs to the aldehyde dehydrogenase family
PD630_RS34160	COG1802	Transcriptional regulator
PD630_RS34185	COG1063	alcohol dehydrogenase
PD630_RS34190	COG1012	belongs to the aldehyde dehydrogenase family
PD630_RS34230	COG0165	Argininosuccinate lyase
PD630_RS34235	COG0477	Major facilitator Superfamily
PD630_RS34245	COG0596	Alpha beta hydrolase
PD630_RS34250	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PD630_RS34260	COG0765	amino acid transport
PD630_RS34265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PD630_RS34270	COG2267	carboxylic ester hydrolase activity
PD630_RS34285	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PD630_RS34285	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PD630_RS34290	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PD630_RS34300	COG0477	Major facilitator Superfamily
PD630_RS34310	COG3608	succinylglutamate desuccinylase aspartoacylase
PD630_RS34310	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
PD630_RS34320	COG0477	Major facilitator Superfamily
PD630_RS34325	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PD630_RS34345	COG0604	alcohol dehydrogenase
PD630_RS34345	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PD630_RS34345	COG3321	synthase
PD630_RS34345	COG4221	oxidoreductase activity
PD630_RS34355	COG1335	isochorismatase
PD630_RS34385	COG2309	aminopeptidase activity
PD630_RS34400	COG0477	Major facilitator Superfamily
PD630_RS34410	COG0477	Major facilitator Superfamily
PD630_RS34415	COG0596	Alpha beta hydrolase
PD630_RS34420	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS34450	COG4221	oxidoreductase activity
PD630_RS34460	COG0604	alcohol dehydrogenase
PD630_RS34460	COG3321	synthase
PD630_RS34460	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS34465	COG2205	protein histidine kinase activity
PD630_RS34470	COG0745	RESPONSE REGULATOR receiver
PD630_RS34490	COG0702	epimerase
PD630_RS34515	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS34545	COG2080	2 iron, 2 sulfur cluster binding
PD630_RS34550	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
PD630_RS34555	COG1529	Aldehyde oxidase and xanthine dehydrogenase
PD630_RS34560	COG3608	succinylglutamate desuccinylase aspartoacylase
PD630_RS34560	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
PD630_RS34565	COG0183	Belongs to the thiolase family
PD630_RS34570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PD630_RS34575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PD630_RS34580	COG0477	Major facilitator Superfamily
PD630_RS34590	COG0477	Major facilitator Superfamily
PD630_RS34595	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PD630_RS34600	COG1063	alcohol dehydrogenase
PD630_RS34605	COG1064	alcohol dehydrogenase
PD630_RS34635	COG1116	anion transmembrane transporter activity
PD630_RS34660	COG2084	Dehydrogenase
PD630_RS34670	COG0477	Major facilitator Superfamily
PD630_RS34690	COG1024	Enoyl-CoA hydratase
PD630_RS34710	COG1012	belongs to the aldehyde dehydrogenase family
PD630_RS34720	COG0477	Major facilitator Superfamily
PD630_RS34745	COG1960	acyl-CoA dehydrogenase activity
PD630_RS34760	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
PD630_RS34770	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PD630_RS34790	COG1012	belongs to the aldehyde dehydrogenase family
PD630_RS34795	COG0477	Major facilitator Superfamily
PD630_RS34810	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS34815	COG2186	Transcriptional regulator
PD630_RS34820	COG1063	alcohol dehydrogenase
PD630_RS34830	COG1176	ABC-type spermidine putrescine transport system, permease component I
PD630_RS34840	COG1012	belongs to the aldehyde dehydrogenase family
PD630_RS34855	COG2301	Belongs to the HpcH HpaI aldolase family
PD630_RS34860	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PD630_RS34885	COG1129	ABC transporter
PD630_RS34895	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PD630_RS34905	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PD630_RS34915	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PD630_RS34940	COG0531	amino acid
PD630_RS34955	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PD630_RS34960	COG1024	Enoyl-CoA hydratase
PD630_RS35000	COG0179	Fumarylacetoacetate (FAA) hydrolase
PD630_RS35035	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PD630_RS35040	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PD630_RS35045	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
PD630_RS35045	COG3608	succinylglutamate desuccinylase aspartoacylase
PD630_RS35110	COG1231	oxidoreductase activity
PD630_RS35110	COG1231	oxidoreductase activity
PD630_RS35145	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PD630_RS35150	COG1012	belongs to the aldehyde dehydrogenase family
PD630_RS35185	COG3185	4-Hydroxyphenylpyruvate dioxygenase
PD630_RS35190	COG1522	sequence-specific DNA binding
PD630_RS35195	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
PD630_RS35200	COG1113	amino acid transport
PD630_RS35210	COG0471	metal ion transport
PD630_RS35220	COG1609	Transcriptional regulator
PD630_RS35250	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
PD630_RS35265	COG0515	serine threonine protein kinase
PD630_RS35265	COG2815	serine threonine protein kinase
PD630_RS35310	COG2409	Drug exporters of the RND superfamily
PD630_RS35345	COG1192	Involved in chromosome partitioning
PD630_RS35365	COG3634	alkyl hydroperoxide reductase activity
PD630_RS35395	COG2207	Transcriptional regulator
PD630_RS35395	COG1917	Cupin 2, conserved barrel domain protein
PD630_RS35425	COG1012	belongs to the aldehyde dehydrogenase family
PD630_RS35440	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PD630_RS35445	COG0436	Aminotransferase
PD630_RS35450	COG1063	alcohol dehydrogenase
PD630_RS35455	COG4221	oxidoreductase activity
PD630_RS35460	COG0477	Major facilitator Superfamily
PD630_RS35470	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
PD630_RS35475	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
PD630_RS35480	COG0583	DNA-binding transcription factor activity
PD630_RS35485	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PD630_RS35490	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS35495	COG3265	gluconokinase activity
PD630_RS35505	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PD630_RS35520	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PD630_RS35530	COG0501	Belongs to the peptidase M48B family
PD630_RS35540	COG0747	negative chemotaxis
PD630_RS35550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PD630_RS35555	COG4172	Belongs to the ABC transporter superfamily
PD630_RS35560	COG4129	membrane
PD630_RS35585	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PD630_RS35590	COG0508	dehydrogenase complex catalyzes the overall conversion of
PD630_RS35605	COG1522	sequence-specific DNA binding
PD630_RS35625	COG1253	flavin adenine dinucleotide binding
PD630_RS35650	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PD630_RS35660	COG2072	flavoprotein involved in K transport
PD630_RS35675	COG1522	sequence-specific DNA binding
PD630_RS35680	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
PD630_RS35725	COG4941	Belongs to the sigma-70 factor family
PD630_RS35770	COG0477	Major facilitator Superfamily
PD630_RS35775	COG1063	alcohol dehydrogenase
PD630_RS35785	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PD630_RS35790	COG2358	TRAP transporter, solute receptor (TAXI family
PD630_RS35800	COG0745	RESPONSE REGULATOR receiver
PD630_RS35805	COG0477	Major facilitator Superfamily
PD630_RS35815	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PD630_RS35820	COG0583	DNA-binding transcription factor activity
PD630_RS35825	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PD630_RS35830	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PD630_RS35830	COG0473	3-isopropylmalate dehydrogenase activity
PD630_RS35835	COG1012	belongs to the aldehyde dehydrogenase family
PD630_RS35860	COG1414	Transcriptional regulator
PD630_RS35875	COG4948	Mandelate Racemase Muconate Lactonizing
PD630_RS35885	COG0129	dihydroxy-acid dehydratase activity
PD630_RS35895	COG0179	Fumarylacetoacetate (FAA) hydrolase
PD630_RS35900	COG0477	Major facilitator Superfamily
PD630_RS35905	COG1414	Transcriptional regulator
PD630_RS35925	COG0477	Major facilitator Superfamily
PD630_RS35930	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PD630_RS35930	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PD630_RS35975	COG2271	Major facilitator Superfamily
PD630_RS35990	COG0446	pyridine nucleotide-disulphide oxidoreductase
PD630_RS35990	COG1902	pentaerythritol trinitrate reductase activity
PD630_RS36020	COG0640	Transcriptional regulator
PD630_RS36025	COG0798	PFAM Bile acid sodium symporter
PD630_RS36030	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PD630_RS36045	COG1929	Belongs to the glycerate kinase type-1 family
PD630_RS36060	COG0673	inositol 2-dehydrogenase activity
PD630_RS36065	COG1609	Transcriptional regulator
PD630_RS36095	COG0596	Alpha beta hydrolase
PD630_RS36115	COG3069	C4-dicarboxylate transmembrane transporter activity
PD630_RS36120	COG1335	isochorismatase
PD630_RS36125	COG1082	Xylose isomerase domain protein TIM barrel
PD630_RS36130	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PD630_RS36135	COG0508	dehydrogenase complex catalyzes the overall conversion of
PD630_RS36140	COG0022	dehydrogenase e1 component
PD630_RS36160	COG0277	FAD linked oxidase domain protein
PD630_RS36175	COG1960	acyl-CoA dehydrogenase activity
PD630_RS36180	COG0183	Belongs to the thiolase family
PD630_RS36200	COG1960	acyl-CoA dehydrogenase activity
PD630_RS36205	COG2301	Belongs to the HpcH HpaI aldolase family
PD630_RS36210	COG0477	Major facilitator Superfamily
PD630_RS36215	COG0427	acetyl-CoA hydrolase
PD630_RS36245	COG1063	alcohol dehydrogenase
PD630_RS36250	COG1012	belongs to the aldehyde dehydrogenase family
PD630_RS36265	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PD630_RS36295	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PD630_RS36300	COG0583	DNA-binding transcription factor activity
PD630_RS36320	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PD630_RS36330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PD630_RS36385	COG0789	Transcriptional regulator
PD630_RS36425	COG1611	Belongs to the LOG family
PD630_RS36430	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PD630_RS36435	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PD630_RS36450	COG1960	acyl-CoA dehydrogenase activity
PD630_RS36460	COG2271	Major facilitator Superfamily
PD630_RS36465	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PD630_RS36470	COG3835	regulator
PD630_RS36500	COG0305	Participates in initiation and elongation during chromosome replication
PD630_RS36505	COG0359	binds to the 23S rRNA
PD630_RS36510	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PD630_RS36515	COG0629	single-stranded DNA binding
PD630_RS36540	COG0657	acetylesterase activity
PD630_RS36545	COG2072	flavoprotein involved in K transport
PD630_RS36565	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PD630_RS36595	COG1695	Transcriptional regulator
PD630_RS36615	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PD630_RS36640	COG3842	ATPase activity
PD630_RS36650	COG3639	organic phosphonate transmembrane transporter activity
PD630_RS36655	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
PD630_RS36660	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
PD630_RS36665	COG3454	Phosphonate metabolism
PD630_RS36670	COG1126	abc transporter atp-binding protein
PD630_RS36705	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
PD630_RS36730	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS36740	COG1063	alcohol dehydrogenase
PD630_RS36765	COG1929	Belongs to the glycerate kinase type-1 family
PD630_RS36770	COG3246	L-lysine catabolic process to acetate
PD630_RS36795	COG0183	Belongs to the thiolase family
PD630_RS36800	COG0318	PFAM AMP-dependent synthetase and ligase
PD630_RS36805	COG0318	PFAM AMP-dependent synthetase and ligase
PD630_RS36825	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PD630_RS36835	COG1960	acyl-CoA dehydrogenase activity
PD630_RS36845	COG1309	transcriptional regulator
PD630_RS36850	COG0765	amino acid transport
PD630_RS36855	COG1126	abc transporter atp-binding protein
PD630_RS36860	COG2902	Dehydrogenase
PD630_RS36865	COG1984	allophanate hydrolase subunit 2
PD630_RS36875	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
PD630_RS36880	COG4336	lyase activity
PD630_RS36885	COG2814	Major facilitator Superfamily
PD630_RS36895	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PD630_RS36905	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PD630_RS36920	COG0247	lactate metabolic process
PD630_RS36925	COG1139	Iron-sulfur cluster binding protein
PD630_RS36930	COG1556	Lactate utilization protein
PD630_RS36940	COG1796	DNA polymerase
PD630_RS36940	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
PD630_RS36955	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
PD630_RS36985	COG2233	PERMEase
PD630_RS36995	COG3608	succinylglutamate desuccinylase aspartoacylase
PD630_RS36995	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
PD630_RS37000	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PD630_RS37005	COG0154	amidase activity
PD630_RS37020	COG0442	prolyl-tRNA aminoacylation
PD630_RS37055	COG1595	DNA-templated transcription, initiation
PD630_RS37070	COG0789	Transcriptional regulator
PD630_RS37095	COG2267	carboxylic ester hydrolase activity
PD630_RS37100	COG3973	AAA domain
PD630_RS37105	COG1819	glycosyl
PD630_RS37140	COG1396	sequence-specific DNA binding
PD630_RS37145	COG0531	amino acid
PD630_RS37150	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PD630_RS37160	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
PD630_RS37170	COG0531	amino acid
PD630_RS37175	COG2217	Heavy metal translocating P-type atpase
PD630_RS37190	COG1937	Protein conserved in bacteria
PD630_RS37195	COG2217	Heavy metal translocating P-type atpase
PD630_RS37205	COG1840	ABC-type Fe3 transport system, periplasmic component
PD630_RS37210	COG3842	ATPase activity
PD630_RS37215	COG4149	molybdate abc transporter
PD630_RS37220	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PD630_RS37225	COG1609	Transcriptional regulator
PD630_RS37235	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PD630_RS37280	COG2855	membrane
PD630_RS37295	COG0280	phosphate acetyltransferase
PD630_RS37300	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PD630_RS37305	COG0686	Belongs to the AlaDH PNT family
PD630_RS37310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PD630_RS37330	COG1228	amidohydrolase
PD630_RS37345	COG3835	regulator
PD630_RS37350	COG1414	Transcriptional regulator
PD630_RS37375	COG1414	Transcriptional regulator
PD630_RS37390	COG0546	phosphoglycolate phosphatase activity
PD630_RS37395	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
PD630_RS37400	COG1113	amino acid transport
PD630_RS37405	COG1113	amino acid transport
PD630_RS37415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PD630_RS37430	COG2022	thiamine diphosphate biosynthetic process
PD630_RS37440	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
PD630_RS37440	COG1796	DNA polymerase
PD630_RS37465	COG4221	oxidoreductase activity
PD630_RS37485	COG3220	belongs to the UPF0276 family
PD630_RS37495	COG2267	carboxylic ester hydrolase activity
PD630_RS37500	COG2186	Transcriptional regulator
PD630_RS37510	COG0492	ferredoxin-NADP+ reductase activity
PD630_RS37525	COG3631	Ketosteroid isomerase-related protein
PD630_RS37530	COG2271	Major facilitator Superfamily
PD630_RS37535	COG1024	Enoyl-CoA hydratase
PD630_RS37545	COG1042	CoA-binding domain protein
PD630_RS37545	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PD630_RS37545	COG0045	succinate-CoA ligase (ADP-forming) activity
PD630_RS37550	COG1028	Short-chain dehydrogenase reductase Sdr
PD630_RS37555	COG1309	transcriptional regulator
PD630_RS37580	COG0495	leucyl-tRNA aminoacylation
PD630_RS37595	COG1725	Transcriptional regulator
PD630_RS37620	COG1678	Uncharacterized ACR, COG1678
PD630_RS37670	COG3585	molybdate ion transport
PD630_RS37675	COG0243	molybdopterin cofactor binding
PD630_RS37680	COG0617	tRNA 3'-terminal CCA addition
PD630_RS37700	COG1595	DNA-templated transcription, initiation
PD630_RS37735	COG3409	Peptidoglycan-binding domain 1 protein
PD630_RS37735	COG0860	N-Acetylmuramoyl-L-alanine amidase
PD630_RS37750	COG1192	Involved in chromosome partitioning
PD630_RS37755	COG0357	Ribosomal RNA small subunit methyltransferase G
PD630_RS37770	COG0706	membrane insertase activity
PD630_RS37915	COG2815	serine threonine protein kinase
PD630_RS37915	COG0515	serine threonine protein kinase
PD630_RS38015	COG0069	glutamate synthase activity
PD630_RS38015	COG0067	glutamate synthase
PD630_RS38015	COG0070	glutamate synthase
PD630_RS38135	COG1022	Amp-dependent synthetase and ligase
PD630_RS38200	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
PD630_RS38475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PD630_RS38575	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
PD630_RS38670	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PD630_RS38730	COG0515	serine threonine protein kinase
PD630_RS38950	COG1022	Amp-dependent synthetase and ligase
PD630_RS39135	COG0768	penicillin binding
PD630_RS39220	COG0067	glutamate synthase
PD630_RS39220	COG0069	glutamate synthase activity
PD630_RS39220	COG0070	glutamate synthase
PD630_RS39285	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PD630_RS39285	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
PD630_RS39350	COG4770	biotin carboxylase activity
PD630_RS39375	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PD630_RS39400	COG0592	DNA-directed DNA polymerase activity
PD630_RS39915	COG0070	glutamate synthase
PD630_RS39915	COG0067	glutamate synthase
PD630_RS39915	COG0069	glutamate synthase activity
PD630_RS40000	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PD630_RS40000	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
PD630_RS40080	COG0318	PFAM AMP-dependent synthetase and ligase
PD630_RS40490	COG0187	DNA topoisomerase II activity
PD630_RS40655	COG0067	glutamate synthase
PD630_RS40655	COG0069	glutamate synthase activity
PD630_RS40655	COG0070	glutamate synthase
PD630_RS41335	COG0789	Transcriptional regulator
PD630_RS41340	COG2301	Belongs to the HpcH HpaI aldolase family
PD630_RS41420	COG0477	Major facilitator Superfamily
PD630_RS41440	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
PD630_RS41445	COG3627	carbon phosphorus lyase activity