locus-tag	class	description
RQCS_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
RQCS_RS00010	COG0592	DNA-directed DNA polymerase activity
RQCS_RS00015	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
RQCS_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
RQCS_RS00025	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
RQCS_RS00050	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
RQCS_RS00090	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
RQCS_RS00095	COG0457	Tetratricopeptide repeat
RQCS_RS00095	COG0705	Rhomboid family
RQCS_RS00115	COG0277	FAD linked oxidase domain protein
RQCS_RS00135	COG3879	Bacterial protein of unknown function (DUF881)
RQCS_RS00145	COG2815	serine threonine protein kinase
RQCS_RS00145	COG0515	serine threonine protein kinase
RQCS_RS00150	COG0515	serine threonine protein kinase
RQCS_RS00155	COG0768	penicillin binding
RQCS_RS00170	COG1716	ATPase activity
RQCS_RS00175	COG1716	ATPase activity
RQCS_RS00195	COG1196	nuclear chromosome segregation
RQCS_RS00220	COG0067	glutamate synthase
RQCS_RS00220	COG0070	glutamate synthase
RQCS_RS00220	COG0069	glutamate synthase activity
RQCS_RS00230	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
RQCS_RS00255	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
RQCS_RS00275	COG0025	NhaP-type Na H and K H
RQCS_RS00285	COG0601	transmembrane transport
RQCS_RS00290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RQCS_RS00295	COG0444	Belongs to the ABC transporter superfamily
RQCS_RS00310	COG2199	diguanylate cyclase activity
RQCS_RS00320	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
RQCS_RS00320	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
RQCS_RS00325	COG2501	S4 domain
RQCS_RS00330	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
RQCS_RS00380	COG0318	PFAM AMP-dependent synthetase and ligase
RQCS_RS00395	COG4716	Myosin-crossreactive antigen
RQCS_RS00410	COG2271	Major facilitator Superfamily
RQCS_RS00425	COG0506	proline dehydrogenase activity
RQCS_RS00445	COG2197	response regulator
RQCS_RS00460	COG1136	(ABC) transporter
RQCS_RS00460	COG0577	efflux transmembrane transporter activity
RQCS_RS00510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RQCS_RS00515	COG1120	ATPase activity
RQCS_RS00550	COG2318	DinB family
RQCS_RS00555	COG1288	antiporter activity
RQCS_RS00580	COG3119	arylsulfatase activity
RQCS_RS00590	COG0175	sulfate reduction
RQCS_RS00595	COG4424	Sulfotransferase
RQCS_RS00630	COG5001	Diguanylate cyclase
RQCS_RS00650	COG1403	HNH endonuclease
RQCS_RS00665	COG0183	Belongs to the thiolase family
RQCS_RS00680	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS00685	COG1960	acyl-CoA dehydrogenase activity
RQCS_RS00690	COG0154	amidase activity
RQCS_RS00720	COG0154	amidase activity
RQCS_RS00730	COG2271	Major facilitator Superfamily
RQCS_RS00740	COG2119	membrane
RQCS_RS00760	COG0628	permease
RQCS_RS00770	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
RQCS_RS00780	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
RQCS_RS00790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RQCS_RS00820	COG1528	Iron-storage protein
RQCS_RS00855	COG1528	Iron-storage protein
RQCS_RS00865	COG1316	TRANSCRIPTIONal
RQCS_RS00950	COG0204	Acyl-transferase
RQCS_RS00965	COG0561	phosphatase activity
RQCS_RS00975	COG2385	sporulation resulting in formation of a cellular spore
RQCS_RS00985	COG1113	amino acid transport
RQCS_RS00990	COG0183	Belongs to the thiolase family
RQCS_RS00995	COG1960	acyl-CoA dehydrogenase activity
RQCS_RS01000	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RQCS_RS01010	COG1216	Glycosyl transferase, family 2
RQCS_RS01020	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
RQCS_RS01025	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
RQCS_RS01030	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
RQCS_RS01035	COG5479	isomerase activity
RQCS_RS01035	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
RQCS_RS01045	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
RQCS_RS01055	COG0318	PFAM AMP-dependent synthetase and ligase
RQCS_RS01060	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
RQCS_RS01060	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RQCS_RS01060	COG3321	synthase
RQCS_RS01065	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
RQCS_RS01125	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS01130	COG0277	FAD linked oxidase domain protein
RQCS_RS01165	COG0183	Belongs to the thiolase family
RQCS_RS01170	COG0318	PFAM AMP-dependent synthetase and ligase
RQCS_RS01180	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RQCS_RS01185	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
RQCS_RS01190	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
RQCS_RS01210	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
RQCS_RS01215	COG0673	inositol 2-dehydrogenase activity
RQCS_RS01225	COG1215	transferase activity, transferring glycosyl groups
RQCS_RS01230	COG1216	Glycosyl transferase, family 2
RQCS_RS01240	COG1162	GTPase activity
RQCS_RS01245	COG1216	Glycosyl transferase, family 2
RQCS_RS01345	COG0831	urea catabolic process
RQCS_RS01355	COG0804	urea catabolic process
RQCS_RS01360	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
RQCS_RS01370	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
RQCS_RS01380	COG4413	Urea transporter
RQCS_RS01385	COG3265	gluconokinase activity
RQCS_RS01390	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS01395	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RQCS_RS01405	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
RQCS_RS01410	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
RQCS_RS01420	COG0477	Major facilitator Superfamily
RQCS_RS01425	COG4221	oxidoreductase activity
RQCS_RS01430	COG1063	alcohol dehydrogenase
RQCS_RS01435	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
RQCS_RS01440	COG0436	Aminotransferase
RQCS_RS01455	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
RQCS_RS01465	COG0737	Belongs to the 5'-nucleotidase family
RQCS_RS01470	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
RQCS_RS01525	COG0270	DNA (cytosine-5-)-methyltransferase activity
RQCS_RS01535	COG0287	Prephenate dehydrogenase
RQCS_RS01545	COG0590	tRNA wobble adenosine to inosine editing
RQCS_RS01570	COG2149	membrane
RQCS_RS01590	COG3706	GGDEF domain
RQCS_RS01600	COG2409	Drug exporters of the RND superfamily
RQCS_RS01620	COG2814	Major facilitator Superfamily
RQCS_RS01650	COG3384	dioxygenase
RQCS_RS01655	COG0508	dehydrogenase complex catalyzes the overall conversion of
RQCS_RS01655	COG0596	Alpha beta hydrolase
RQCS_RS01660	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RQCS_RS01670	COG1116	anion transmembrane transporter activity
RQCS_RS01685	COG0492	ferredoxin-NADP+ reductase activity
RQCS_RS01695	COG0508	dehydrogenase complex catalyzes the overall conversion of
RQCS_RS01695	COG0596	Alpha beta hydrolase
RQCS_RS01700	COG1414	Transcriptional regulator
RQCS_RS01715	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RQCS_RS01725	COG1024	Enoyl-CoA hydratase
RQCS_RS01730	COG0343	queuine tRNA-ribosyltransferase activity
RQCS_RS01755	COG3300	MHYT domain
RQCS_RS01755	COG5001	Diguanylate cyclase
RQCS_RS01760	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
RQCS_RS01765	COG3226	Transcriptional regulator
RQCS_RS01795	COG0745	RESPONSE REGULATOR receiver
RQCS_RS01805	COG1357	PFAM Pentapeptide repeats (8 copies)
RQCS_RS01830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RQCS_RS01845	COG0583	DNA-binding transcription factor activity
RQCS_RS01850	COG2855	membrane
RQCS_RS01865	COG2175	clavaminate synthase activity
RQCS_RS01870	COG3246	L-lysine catabolic process to acetate
RQCS_RS01875	COG2814	Major facilitator Superfamily
RQCS_RS01885	COG0318	PFAM AMP-dependent synthetase and ligase
RQCS_RS01915	COG2132	Multicopper oxidase
RQCS_RS01920	COG0183	Belongs to the thiolase family
RQCS_RS01935	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
RQCS_RS01960	COG0860	N-Acetylmuramoyl-L-alanine amidase
RQCS_RS01965	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
RQCS_RS01970	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
RQCS_RS01975	COG1309	transcriptional regulator
RQCS_RS01980	COG2814	Major facilitator Superfamily
RQCS_RS01985	COG1309	transcriptional regulator
RQCS_RS02005	COG0183	Belongs to the thiolase family
RQCS_RS02020	COG0183	Belongs to the thiolase family
RQCS_RS02025	COG1960	acyl-CoA dehydrogenase activity
RQCS_RS02030	COG1960	acyl-CoA dehydrogenase activity
RQCS_RS02035	COG1960	acyl-CoA dehydrogenase activity
RQCS_RS02050	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
RQCS_RS02055	COG0697	spore germination
RQCS_RS02060	COG0583	DNA-binding transcription factor activity
RQCS_RS02070	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RQCS_RS02130	COG2132	Multicopper oxidase
RQCS_RS02135	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RQCS_RS02140	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RQCS_RS02155	COG4585	Histidine kinase
RQCS_RS02165	COG4566	intracellular signal transduction
RQCS_RS02200	COG0546	phosphoglycolate phosphatase activity
RQCS_RS02205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RQCS_RS02210	COG2205	protein histidine kinase activity
RQCS_RS02250	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RQCS_RS02275	COG1408	metallophosphoesterase
RQCS_RS02315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RQCS_RS02335	COG4101	3-hydroxyanthranilate 3,4-dioxygenase activity
RQCS_RS02345	COG0477	Major facilitator Superfamily
RQCS_RS02350	COG0583	DNA-binding transcription factor activity
RQCS_RS02360	COG1309	transcriptional regulator
RQCS_RS02390	COG0494	nUDIX hydrolase
RQCS_RS02400	COG0596	Alpha beta hydrolase
RQCS_RS02410	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
RQCS_RS02415	COG0477	Major facilitator Superfamily
RQCS_RS02450	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RQCS_RS02460	COG0601	transmembrane transport
RQCS_RS02465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RQCS_RS02470	COG4172	Belongs to the ABC transporter superfamily
RQCS_RS02520	COG1111	helicase
RQCS_RS02520	COG1205	dead DEAH box helicase
RQCS_RS02525	COG1278	Cold shock
RQCS_RS02535	COG1754	DNA topoisomerase type I activity
RQCS_RS02535	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
RQCS_RS02540	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
RQCS_RS02550	COG1714	RDD family
RQCS_RS02585	COG3836	Belongs to the HpcH HpaI aldolase family
RQCS_RS02590	COG0667	Aldo Keto reductase
RQCS_RS02595	COG4608	Belongs to the ABC transporter superfamily
RQCS_RS02600	COG0444	Belongs to the ABC transporter superfamily
RQCS_RS02605	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RQCS_RS02610	COG0601	transmembrane transport
RQCS_RS02615	COG0747	negative chemotaxis
RQCS_RS02620	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
RQCS_RS02625	COG1349	DNA-binding transcription factor activity
RQCS_RS02645	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RQCS_RS02650	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RQCS_RS02670	COG3300	MHYT domain
RQCS_RS02670	COG5001	Diguanylate cyclase
RQCS_RS02675	COG1802	Transcriptional regulator
RQCS_RS02685	COG2268	Band 7 protein
RQCS_RS02725	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS02800	COG0477	Major facilitator Superfamily
RQCS_RS02840	COG1937	Protein conserved in bacteria
RQCS_RS02860	COG2226	methyltransferase
RQCS_RS02870	COG1396	sequence-specific DNA binding
RQCS_RS02875	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RQCS_RS02905	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RQCS_RS02910	COG0442	prolyl-tRNA aminoacylation
RQCS_RS02920	COG1309	transcriptional regulator
RQCS_RS02925	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
RQCS_RS02930	COG1285	pathogenesis
RQCS_RS02980	COG1358	cellular component organization or biogenesis
RQCS_RS02995	COG2755	lipolytic protein G-D-S-L family
RQCS_RS03025	COG1309	transcriptional regulator
RQCS_RS03045	COG1316	TRANSCRIPTIONal
RQCS_RS03065	COG2027	D-alanyl-D-alanine carboxypeptidase
RQCS_RS03075	COG0037	tRNA processing
RQCS_RS03090	COG0318	PFAM AMP-dependent synthetase and ligase
RQCS_RS03100	COG2186	Transcriptional regulator
RQCS_RS03105	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RQCS_RS03110	COG0302	gtp cyclohydrolase
RQCS_RS03145	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
RQCS_RS03150	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
RQCS_RS03155	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
RQCS_RS03185	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
RQCS_RS03220	COG1024	Enoyl-CoA hydratase
RQCS_RS03230	COG1309	transcriptional regulator
RQCS_RS03250	COG4585	Histidine kinase
RQCS_RS03255	COG2197	response regulator
RQCS_RS03325	COG1194	a g-specific adenine glycosylase
RQCS_RS03365	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
RQCS_RS03375	COG0288	reversible hydration of carbon dioxide
RQCS_RS03385	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
RQCS_RS03395	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
RQCS_RS03405	COG1329	Transcriptional regulator
RQCS_RS03410	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
RQCS_RS03415	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
RQCS_RS03420	COG0215	cysteine-tRNA ligase activity
RQCS_RS03425	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RQCS_RS03430	COG1132	(ABC) transporter
RQCS_RS03435	COG1132	(ABC) transporter
RQCS_RS03465	COG1984	allophanate hydrolase subunit 2
RQCS_RS03470	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
RQCS_RS03475	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
RQCS_RS03480	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RQCS_RS03485	COG1121	(ABC) transporter
RQCS_RS03490	COG0803	Belongs to the bacterial solute-binding protein 9 family
RQCS_RS03495	COG1609	Transcriptional regulator
RQCS_RS03505	COG1309	transcriptional regulator
RQCS_RS03510	COG1960	acyl-CoA dehydrogenase activity
RQCS_RS03515	COG1960	acyl-CoA dehydrogenase activity
RQCS_RS03520	COG1960	acyl-CoA dehydrogenase activity
RQCS_RS03535	COG0183	Belongs to the thiolase family
RQCS_RS03545	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RQCS_RS03595	COG2890	protein-(glutamine-N5) methyltransferase activity
RQCS_RS03610	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
RQCS_RS03635	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
RQCS_RS03660	COG2030	dehydratase
RQCS_RS03665	COG1053	succinate dehydrogenase
RQCS_RS03675	COG3971	2-oxopent-4-enoate hydratase activity
RQCS_RS03680	COG4569	acetaldehyde dehydrogenase (acetylating) activity
RQCS_RS03685	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RQCS_RS03710	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RQCS_RS03750	COG1960	acyl-CoA dehydrogenase activity
RQCS_RS03755	COG2267	carboxylic ester hydrolase activity
RQCS_RS03760	COG0346	lactoylglutathione lyase activity
RQCS_RS03765	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RQCS_RS03780	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
RQCS_RS03790	COG2814	Major facilitator Superfamily
RQCS_RS03800	COG4689	acetoacetate decarboxylase
RQCS_RS03805	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS03810	COG2124	cytochrome p450
RQCS_RS03850	COG1116	anion transmembrane transporter activity
RQCS_RS03860	COG1074	ATP-dependent DNA helicase activity
RQCS_RS03880	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
RQCS_RS03890	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RQCS_RS03915	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
RQCS_RS03940	COG0656	L-ascorbic acid biosynthetic process
RQCS_RS03945	COG0686	Belongs to the AlaDH PNT family
RQCS_RS03965	COG0346	lactoylglutathione lyase activity
RQCS_RS03975	COG0561	phosphatase activity
RQCS_RS03995	COG1960	acyl-CoA dehydrogenase activity
RQCS_RS04000	COG1960	acyl-CoA dehydrogenase activity
RQCS_RS04005	COG1960	acyl-CoA dehydrogenase activity
RQCS_RS04010	COG1024	Enoyl-CoA hydratase
RQCS_RS04015	COG0318	PFAM AMP-dependent synthetase and ligase
RQCS_RS04020	COG1960	acyl-CoA dehydrogenase activity
RQCS_RS04025	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS04030	COG1309	transcriptional regulator
RQCS_RS04035	COG0183	Belongs to the thiolase family
RQCS_RS04075	COG0494	nUDIX hydrolase
RQCS_RS04125	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
RQCS_RS04140	COG3214	Protein conserved in bacteria
RQCS_RS04155	COG1414	Transcriptional regulator
RQCS_RS04175	COG1024	Enoyl-CoA hydratase
RQCS_RS04180	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS04200	COG0183	Belongs to the thiolase family
RQCS_RS04205	COG2124	cytochrome p450
RQCS_RS04225	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
RQCS_RS04230	COG0183	Belongs to the thiolase family
RQCS_RS04240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RQCS_RS04260	COG2070	2-Nitropropane dioxygenase
RQCS_RS04270	COG2186	Transcriptional regulator
RQCS_RS04275	COG4608	Belongs to the ABC transporter superfamily
RQCS_RS04280	COG0444	Belongs to the ABC transporter superfamily
RQCS_RS04285	COG0601	transmembrane transport
RQCS_RS04290	COG0747	negative chemotaxis
RQCS_RS04300	COG0673	inositol 2-dehydrogenase activity
RQCS_RS04305	COG0673	inositol 2-dehydrogenase activity
RQCS_RS04310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RQCS_RS04315	COG1940	carbohydrate kinase activity
RQCS_RS04330	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
RQCS_RS04340	COG0318	PFAM AMP-dependent synthetase and ligase
RQCS_RS04345	COG1960	acyl-CoA dehydrogenase activity
RQCS_RS04350	COG1960	acyl-CoA dehydrogenase activity
RQCS_RS04370	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
RQCS_RS04395	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
RQCS_RS04415	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
RQCS_RS04425	COG1132	(ABC) transporter
RQCS_RS04430	COG1132	(ABC) transporter
RQCS_RS04445	COG1937	Protein conserved in bacteria
RQCS_RS04455	COG2409	Drug exporters of the RND superfamily
RQCS_RS04500	COG2076	Multidrug Resistance protein
RQCS_RS04515	COG0745	RESPONSE REGULATOR receiver
RQCS_RS04520	COG2205	protein histidine kinase activity
RQCS_RS04540	COG2271	Major facilitator Superfamily
RQCS_RS04545	COG3483	tryptophan 2,3-dioxygenase activity
RQCS_RS04560	COG4948	Mandelate Racemase Muconate Lactonizing
RQCS_RS04580	COG0537	adenosine 5'-monophosphoramidase activity
RQCS_RS04590	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
RQCS_RS04605	COG0444	Belongs to the ABC transporter superfamily
RQCS_RS04610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RQCS_RS04615	COG0601	transmembrane transport
RQCS_RS04645	COG0671	phosphoesterase, PA-phosphatase related
RQCS_RS04650	COG0745	RESPONSE REGULATOR receiver
RQCS_RS04655	COG2205	protein histidine kinase activity
RQCS_RS04680	COG0436	Aminotransferase
RQCS_RS04690	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
RQCS_RS04705	COG2382	esterase
RQCS_RS04710	COG4592	Periplasmic binding protein
RQCS_RS04715	COG4585	Histidine kinase
RQCS_RS04720	COG2197	response regulator
RQCS_RS04725	COG2365	Tyrosine phosphatase family
RQCS_RS04735	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
RQCS_RS04745	COG4565	transcriptional regulatory protein
RQCS_RS04750	COG3290	protein histidine kinase activity
RQCS_RS04755	COG1301	dicarboxylic acid transport
RQCS_RS04775	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RQCS_RS04780	COG0386	Belongs to the glutathione peroxidase family
RQCS_RS04800	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
RQCS_RS04805	COG0047	phosphoribosylformylglycinamidine synthase activity
RQCS_RS04815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RQCS_RS04835	COG2205	protein histidine kinase activity
RQCS_RS04840	COG0745	RESPONSE REGULATOR receiver
RQCS_RS04850	COG2217	Heavy metal translocating P-type atpase
RQCS_RS04865	COG0488	(ABC) transporter
RQCS_RS04875	COG0768	penicillin binding
RQCS_RS04890	COG3104	oligopeptide transport
RQCS_RS04905	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RQCS_RS04930	COG4585	Histidine kinase
RQCS_RS04935	COG2197	response regulator
RQCS_RS04955	COG1309	transcriptional regulator
RQCS_RS04965	COG2409	Drug exporters of the RND superfamily
RQCS_RS04975	COG0220	tRNA (guanine-N7-)-methyltransferase activity
RQCS_RS04995	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
RQCS_RS05005	COG1045	serine acetyltransferase
RQCS_RS05030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RQCS_RS05035	COG1120	ATPase activity
RQCS_RS05065	COG1940	carbohydrate kinase activity
RQCS_RS05070	COG0500	methyltransferase
RQCS_RS05105	COG4981	capsule polysaccharide biosynthetic process
RQCS_RS05125	COG1472	Belongs to the glycosyl hydrolase 3 family
RQCS_RS05130	COG1309	transcriptional regulator
RQCS_RS05135	COG2030	dehydratase
RQCS_RS05140	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS05145	COG0183	Belongs to the thiolase family
RQCS_RS05155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RQCS_RS05165	COG1476	TRANSCRIPTIONal
RQCS_RS05190	COG1960	acyl-CoA dehydrogenase activity
RQCS_RS05205	COG1136	(ABC) transporter
RQCS_RS05205	COG0577	efflux transmembrane transporter activity
RQCS_RS05210	COG4585	Histidine kinase
RQCS_RS05215	COG2197	response regulator
RQCS_RS05240	COG2267	carboxylic ester hydrolase activity
RQCS_RS05275	COG2015	COG2015, Alkyl sulfatase and related hydrolases
RQCS_RS05280	COG0009	L-threonylcarbamoyladenylate synthase
RQCS_RS05285	COG0789	Transcriptional regulator
RQCS_RS05290	COG0659	secondary active sulfate transmembrane transporter activity
RQCS_RS05360	COG2837	iron assimilation
RQCS_RS05395	COG0501	Belongs to the peptidase M48B family
RQCS_RS05410	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
RQCS_RS05420	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
RQCS_RS05455	COG3707	response regulator
RQCS_RS05460	COG0596	Alpha beta hydrolase
RQCS_RS05495	COG0738	Major facilitator superfamily
RQCS_RS05515	COG0318	PFAM AMP-dependent synthetase and ligase
RQCS_RS05525	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RQCS_RS05535	COG1120	ATPase activity
RQCS_RS05540	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RQCS_RS05545	COG2226	methyltransferase
RQCS_RS05565	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS05615	COG0183	Belongs to the thiolase family
RQCS_RS05645	COG2015	COG2015, Alkyl sulfatase and related hydrolases
RQCS_RS05655	COG0477	Major facilitator Superfamily
RQCS_RS05660	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
RQCS_RS05665	COG1737	Transcriptional regulator
RQCS_RS05670	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
RQCS_RS05685	COG0515	serine threonine protein kinase
RQCS_RS05685	COG2815	serine threonine protein kinase
RQCS_RS05700	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
RQCS_RS05715	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
RQCS_RS05780	COG1053	succinate dehydrogenase
RQCS_RS05785	COG0739	heme binding
RQCS_RS05805	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RQCS_RS05865	COG1131	(ABC) transporter
RQCS_RS05870	COG2188	Transcriptional regulator
RQCS_RS05925	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
RQCS_RS06010	COG0582	viral genome integration into host DNA
RQCS_RS06020	COG0717	Belongs to the dCTP deaminase family
RQCS_RS06085	COG2890	protein-(glutamine-N5) methyltransferase activity
RQCS_RS06100	COG1278	Cold shock
RQCS_RS06150	COG0783	Belongs to the Dps family
RQCS_RS06160	COG0789	Transcriptional regulator
RQCS_RS06195	COG1595	DNA-templated transcription, initiation
RQCS_RS06200	COG1302	Protein conserved in bacteria
RQCS_RS06265	COG1210	Utp--glucose-1-phosphate uridylyltransferase
RQCS_RS06275	COG1215	transferase activity, transferring glycosyl groups
RQCS_RS06315	COG2244	polysaccharide biosynthetic process
RQCS_RS06320	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
RQCS_RS06325	COG0489	protein tyrosine kinase activity
RQCS_RS06360	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
RQCS_RS06365	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
RQCS_RS06370	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RQCS_RS06375	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
RQCS_RS06380	COG0489	protein tyrosine kinase activity
RQCS_RS06385	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
RQCS_RS06390	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
RQCS_RS06395	COG0443	Heat shock 70 kDa protein
RQCS_RS06410	COG4946	Tricorn protease homolog
RQCS_RS06410	COG1506	peptidase
RQCS_RS06410	COG0823	Involved in the tonB-independent uptake of proteins
RQCS_RS06430	COG0247	lactate metabolic process
RQCS_RS06430	COG2181	nitrate reductase activity
RQCS_RS06480	COG0477	Major facilitator Superfamily
RQCS_RS06485	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
RQCS_RS06500	COG0443	Heat shock 70 kDa protein
RQCS_RS06505	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
RQCS_RS06510	COG0484	heat shock protein binding
RQCS_RS06515	COG0789	Transcriptional regulator
RQCS_RS06560	COG2072	flavoprotein involved in K transport
RQCS_RS06585	COG3976	FMN-binding domain protein
RQCS_RS06585	COG1053	succinate dehydrogenase
RQCS_RS06615	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
RQCS_RS06635	COG3631	Ketosteroid isomerase-related protein
RQCS_RS06640	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RQCS_RS06650	COG1414	Transcriptional regulator
RQCS_RS06675	COG0318	PFAM AMP-dependent synthetase and ligase
RQCS_RS06685	COG3290	protein histidine kinase activity
RQCS_RS06695	COG2851	Citrate transporter
RQCS_RS06720	COG0542	response to heat
RQCS_RS06745	COG2814	Major facilitator Superfamily
RQCS_RS06755	COG1309	transcriptional regulator
RQCS_RS06775	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS06805	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RQCS_RS06810	COG0523	cobalamin synthesis protein
RQCS_RS06815	COG0586	Pfam SNARE associated Golgi protein
RQCS_RS06840	COG4129	membrane
RQCS_RS06860	COG2354	Protein conserved in bacteria
RQCS_RS06865	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
RQCS_RS06870	COG0183	Belongs to the thiolase family
RQCS_RS06895	COG1994	Peptidase M50
RQCS_RS06905	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
RQCS_RS06920	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RQCS_RS06930	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RQCS_RS06950	COG3706	GGDEF domain
RQCS_RS06955	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
RQCS_RS06980	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
RQCS_RS07005	COG0681	Belongs to the peptidase S26 family
RQCS_RS07035	COG1126	abc transporter atp-binding protein
RQCS_RS07040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RQCS_RS07055	COG0747	negative chemotaxis
RQCS_RS07065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RQCS_RS07070	COG4172	Belongs to the ABC transporter superfamily
RQCS_RS07075	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RQCS_RS07090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RQCS_RS07095	COG0037	tRNA processing
RQCS_RS07095	COG0590	tRNA wobble adenosine to inosine editing
RQCS_RS07115	COG2149	membrane
RQCS_RS07120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RQCS_RS07130	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
RQCS_RS07140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RQCS_RS07155	COG0352	thiamine-phosphate diphosphorylase activity
RQCS_RS07160	COG2022	thiamine diphosphate biosynthetic process
RQCS_RS07160	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RQCS_RS07170	COG2022	thiamine diphosphate biosynthetic process
RQCS_RS07175	COG1131	(ABC) transporter
RQCS_RS07185	COG2234	aminopeptidase activity
RQCS_RS07195	COG0351	phosphomethylpyrimidine kinase
RQCS_RS07210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RQCS_RS07210	COG0456	acetyltransferase
RQCS_RS07235	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
RQCS_RS07245	COG1320	monovalent cation:proton antiporter activity
RQCS_RS07255	COG1863	multisubunit Na H antiporter MnhE subunit
RQCS_RS07260	COG0651	ATP synthesis coupled electron transport
RQCS_RS07295	COG2124	cytochrome p450
RQCS_RS07325	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RQCS_RS07330	COG1183	phosphatidylcholine synthase activity
RQCS_RS07335	COG0688	phosphatidylethanolamine metabolic process
RQCS_RS07370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RQCS_RS07375	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
RQCS_RS07375	COG2508	Transcriptional regulator
RQCS_RS07390	COG0459	protein refolding
RQCS_RS07430	COG2326	polyphosphate kinase activity
RQCS_RS07440	COG1505	serine-type exopeptidase activity
RQCS_RS07470	COG1733	regulation of RNA biosynthetic process
RQCS_RS07475	COG0702	epimerase
RQCS_RS07495	COG1802	Transcriptional regulator
RQCS_RS07505	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS07515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RQCS_RS07520	COG1802	Transcriptional regulator
RQCS_RS07550	COG1309	transcriptional regulator
RQCS_RS07560	COG1172	Belongs to the binding-protein-dependent transport system permease family
RQCS_RS07570	COG1137	ATPase activity
RQCS_RS07575	COG0410	ABC transporter
RQCS_RS07580	COG0318	PFAM AMP-dependent synthetase and ligase
RQCS_RS07615	COG2224	Isocitrate lyase
RQCS_RS07625	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
RQCS_RS07630	COG1064	alcohol dehydrogenase
RQCS_RS07650	COG0297	glycogen (starch) synthase activity
RQCS_RS07670	COG2326	polyphosphate kinase activity
RQCS_RS07680	COG2733	membrane
RQCS_RS07700	COG0596	Alpha beta hydrolase
RQCS_RS07710	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
RQCS_RS07750	COG0812	UDP-N-acetylmuramate dehydrogenase activity
RQCS_RS07810	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
RQCS_RS07825	COG0438	transferase activity, transferring glycosyl groups
RQCS_RS07835	COG0318	PFAM AMP-dependent synthetase and ligase
RQCS_RS07845	COG5002	protein histidine kinase activity
RQCS_RS07850	COG0745	RESPONSE REGULATOR receiver
RQCS_RS07940	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
RQCS_RS07945	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
RQCS_RS07950	COG0181	hydroxymethylbilane synthase activity
RQCS_RS07955	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
RQCS_RS07955	COG1587	Uroporphyrinogen-III synthase
RQCS_RS07990	COG1937	Protein conserved in bacteria
RQCS_RS08000	COG1218	3'(2'),5'-bisphosphate nucleotidase
RQCS_RS08005	COG0175	sulfate reduction
RQCS_RS08020	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS08065	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
RQCS_RS08070	COG0406	alpha-ribazole phosphatase activity
RQCS_RS08080	COG0785	Cytochrome C biogenesis protein
RQCS_RS08090	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RQCS_RS08115	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RQCS_RS08135	COG0542	response to heat
RQCS_RS08140	COG1950	PFAM Membrane protein of
RQCS_RS08200	COG0559	Belongs to the binding-protein-dependent transport system permease family
RQCS_RS08210	COG0410	ABC transporter
RQCS_RS08235	COG4948	Mandelate Racemase Muconate Lactonizing
RQCS_RS08250	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RQCS_RS08255	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
RQCS_RS08265	COG0438	transferase activity, transferring glycosyl groups
RQCS_RS08275	COG0644	oxidoreductase
RQCS_RS08280	COG0142	geranyltranstransferase activity
RQCS_RS08285	COG0501	Belongs to the peptidase M48B family
RQCS_RS08290	COG1666	GTP binding
RQCS_RS08310	COG0267	Belongs to the bacterial ribosomal protein bL33 family
RQCS_RS08315	COG2030	dehydratase
RQCS_RS08340	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
RQCS_RS08345	COG0081	regulation of translation
RQCS_RS08355	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
RQCS_RS08370	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
RQCS_RS08375	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
RQCS_RS08400	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
RQCS_RS08420	COG0085	RNA polymerase activity
RQCS_RS08425	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
RQCS_RS08435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RQCS_RS08455	COG0604	alcohol dehydrogenase
RQCS_RS08465	COG0604	alcohol dehydrogenase
RQCS_RS08475	COG0477	Major facilitator Superfamily
RQCS_RS08480	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RQCS_RS08505	COG1024	Enoyl-CoA hydratase
RQCS_RS08520	COG1960	acyl-CoA dehydrogenase activity
RQCS_RS08525	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
RQCS_RS08560	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
RQCS_RS08565	COG0049	tRNA binding
RQCS_RS08570	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
RQCS_RS08575	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
RQCS_RS08610	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
RQCS_RS08665	COG1454	alcohol dehydrogenase
RQCS_RS08670	COG4585	Histidine kinase
RQCS_RS08690	COG1131	(ABC) transporter
RQCS_RS08695	COG3559	Exporter of polyketide antibiotics
RQCS_RS08740	COG0535	radical SAM domain protein
RQCS_RS08755	COG1902	pentaerythritol trinitrate reductase activity
RQCS_RS08755	COG0446	pyridine nucleotide-disulphide oxidoreductase
RQCS_RS08765	COG1902	pentaerythritol trinitrate reductase activity
RQCS_RS08765	COG0446	pyridine nucleotide-disulphide oxidoreductase
RQCS_RS08805	COG0531	amino acid
RQCS_RS08810	COG4303	Ethanolamine ammonia lyase large subunit
RQCS_RS08830	COG0477	Major facilitator Superfamily
RQCS_RS08835	COG0318	PFAM AMP-dependent synthetase and ligase
RQCS_RS08845	COG1012	belongs to the aldehyde dehydrogenase family
RQCS_RS08860	COG2409	Drug exporters of the RND superfamily
RQCS_RS08895	COG0179	Fumarylacetoacetate (FAA) hydrolase
RQCS_RS08900	COG0318	PFAM AMP-dependent synthetase and ligase
RQCS_RS08905	COG1216	Glycosyl transferase, family 2
RQCS_RS08910	COG1301	dicarboxylic acid transport
RQCS_RS08920	COG2357	RelA SpoT domain protein
RQCS_RS08925	COG1309	transcriptional regulator
RQCS_RS08930	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
RQCS_RS08940	COG1960	acyl-CoA dehydrogenase activity
RQCS_RS08945	COG2030	dehydratase
RQCS_RS08985	COG5479	isomerase activity
RQCS_RS08985	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
RQCS_RS09005	COG1215	transferase activity, transferring glycosyl groups
RQCS_RS09015	COG0287	Prephenate dehydrogenase
RQCS_RS09020	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
RQCS_RS09020	COG0512	Glutamine amidotransferase of anthranilate synthase
RQCS_RS09025	COG1605	Chorismate mutase
RQCS_RS09035	COG0051	transcription antitermination factor activity, RNA binding
RQCS_RS09040	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
RQCS_RS09045	COG0088	Forms part of the polypeptide exit tunnel
RQCS_RS09050	COG0089	rRNA binding
RQCS_RS09055	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
RQCS_RS09060	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
RQCS_RS09065	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
RQCS_RS09070	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
RQCS_RS09075	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
RQCS_RS09080	COG0255	Belongs to the universal ribosomal protein uL29 family
RQCS_RS09085	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
RQCS_RS09090	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
RQCS_RS09095	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
RQCS_RS09100	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
RQCS_RS09105	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
RQCS_RS09110	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
RQCS_RS09115	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
RQCS_RS09120	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
RQCS_RS09125	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
RQCS_RS09130	COG1841	ribosomal large subunit assembly
RQCS_RS09135	COG0200	Binds to the 23S rRNA
RQCS_RS09140	COG0201	protein transport
RQCS_RS09145	COG0563	adenylate kinase activity
RQCS_RS09155	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
RQCS_RS09160	COG0257	Belongs to the bacterial ribosomal protein bL36 family
RQCS_RS09165	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
RQCS_RS09170	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
RQCS_RS09175	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
RQCS_RS09180	COG0202	RNA polymerase activity
RQCS_RS09185	COG0203	ribosomal protein L17
RQCS_RS09190	COG0101	tRNA pseudouridine synthase activity
RQCS_RS09195	COG1960	acyl-CoA dehydrogenase activity
RQCS_RS09220	COG1404	Belongs to the peptidase S8 family
RQCS_RS09230	COG1674	ftsk spoiiie
RQCS_RS09250	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
RQCS_RS09255	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
RQCS_RS09260	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
RQCS_RS09285	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
RQCS_RS09300	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
RQCS_RS09320	COG0456	acetyltransferase
RQCS_RS09325	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
RQCS_RS09345	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
RQCS_RS09350	COG0459	protein refolding
RQCS_RS09400	COG0516	GMP reductase activity
RQCS_RS09420	COG0519	Catalyzes the synthesis of GMP from XMP
RQCS_RS09420	COG0518	GMP synthase (glutamine-hydrolyzing) activity
RQCS_RS09450	COG2271	Major facilitator Superfamily
RQCS_RS09455	COG2205	protein histidine kinase activity
RQCS_RS09460	COG0745	RESPONSE REGULATOR receiver
RQCS_RS09475	COG1733	regulation of RNA biosynthetic process
RQCS_RS09490	COG0515	serine threonine protein kinase
RQCS_RS09490	COG2815	serine threonine protein kinase
RQCS_RS09520	COG3119	arylsulfatase activity
RQCS_RS09525	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RQCS_RS09570	COG2249	NAD(P)H dehydrogenase (quinone) activity
RQCS_RS09580	COG0583	DNA-binding transcription factor activity
RQCS_RS09590	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
RQCS_RS09595	COG2271	Major facilitator Superfamily
RQCS_RS09615	COG4585	Histidine kinase
RQCS_RS09620	COG2197	response regulator
RQCS_RS09625	COG4221	oxidoreductase activity
RQCS_RS09645	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RQCS_RS09650	COG1120	ATPase activity
RQCS_RS09665	COG0587	DNA-directed DNA polymerase activity
RQCS_RS09675	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS09680	COG3321	synthase
RQCS_RS09680	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS09680	COG0604	alcohol dehydrogenase
RQCS_RS09720	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RQCS_RS09730	COG0243	molybdopterin cofactor binding
RQCS_RS09735	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
RQCS_RS09760	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
RQCS_RS09775	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
RQCS_RS09780	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
RQCS_RS09785	COG2873	o-acetylhomoserine
RQCS_RS09795	COG2814	Major facilitator Superfamily
RQCS_RS09800	COG0708	Exodeoxyribonuclease III
RQCS_RS09815	COG0180	Tryptophanyl-tRNA synthetase
RQCS_RS09820	COG1295	ribonuclease BN
RQCS_RS09825	COG1686	Belongs to the peptidase S11 family
RQCS_RS09840	COG1082	Xylose isomerase domain protein TIM barrel
RQCS_RS09845	COG0673	inositol 2-dehydrogenase activity
RQCS_RS09855	COG3962	Belongs to the TPP enzyme family
RQCS_RS09860	COG3718	enzyme involved in inositol metabolism
RQCS_RS09875	COG2188	Transcriptional regulator
RQCS_RS09885	COG2814	Major facilitator Superfamily
RQCS_RS09890	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RQCS_RS09895	COG0242	peptide deformylase activity
RQCS_RS09910	COG0673	inositol 2-dehydrogenase activity
RQCS_RS09915	COG0673	inositol 2-dehydrogenase activity
RQCS_RS09920	COG3622	Belongs to the hyi family
RQCS_RS09925	COG0673	inositol 2-dehydrogenase activity
RQCS_RS09930	COG1609	Transcriptional regulator
RQCS_RS09940	COG1172	Belongs to the binding-protein-dependent transport system permease family
RQCS_RS09960	COG0673	inositol 2-dehydrogenase activity
RQCS_RS09965	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS09975	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
RQCS_RS09980	COG1053	succinate dehydrogenase
RQCS_RS09990	COG2009	succinate dehydrogenase
RQCS_RS10025	COG0741	lytic transglycosylase activity
RQCS_RS10025	COG0791	NLP P60 protein
RQCS_RS10035	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
RQCS_RS10040	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
RQCS_RS10060	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
RQCS_RS10060	COG1473	amidohydrolase
RQCS_RS10085	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
RQCS_RS10090	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
RQCS_RS10095	COG0583	DNA-binding transcription factor activity
RQCS_RS10100	COG0477	Major facilitator Superfamily
RQCS_RS10105	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
RQCS_RS10110	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
RQCS_RS10135	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS10170	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
RQCS_RS10175	COG1201	RNA secondary structure unwinding
RQCS_RS10200	COG2233	PERMEase
RQCS_RS10205	COG3491	Belongs to the iron ascorbate-dependent oxidoreductase family
RQCS_RS10215	COG1012	belongs to the aldehyde dehydrogenase family
RQCS_RS10225	COG1522	sequence-specific DNA binding
RQCS_RS10235	COG1529	Aldehyde oxidase and xanthine dehydrogenase
RQCS_RS10255	COG2351	hydroxyisourate hydrolase activity
RQCS_RS10285	COG4770	biotin carboxylase activity
RQCS_RS10315	COG0477	Major facilitator Superfamily
RQCS_RS10325	COG0424	maF-like protein
RQCS_RS10335	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
RQCS_RS10340	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
RQCS_RS10340	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
RQCS_RS10355	COG0745	RESPONSE REGULATOR receiver
RQCS_RS10360	COG2205	protein histidine kinase activity
RQCS_RS10370	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
RQCS_RS10385	COG4585	Histidine kinase
RQCS_RS10390	COG2197	response regulator
RQCS_RS10395	COG1136	(ABC) transporter
RQCS_RS10395	COG0577	efflux transmembrane transporter activity
RQCS_RS10410	COG1316	TRANSCRIPTIONal
RQCS_RS10425	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
RQCS_RS10440	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
RQCS_RS10440	COG0778	Nitroreductase
RQCS_RS10465	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
RQCS_RS10475	COG1482	cell wall glycoprotein biosynthetic process
RQCS_RS10485	COG0531	amino acid
RQCS_RS10490	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RQCS_RS10525	COG5002	protein histidine kinase activity
RQCS_RS10530	COG5401	PFAM Sporulation and spore germination
RQCS_RS10540	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
RQCS_RS10545	COG0653	protein targeting
RQCS_RS10585	COG1162	GTPase activity
RQCS_RS10590	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
RQCS_RS10620	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
RQCS_RS10635	COG1597	lipid kinase activity
RQCS_RS10650	COG0406	alpha-ribazole phosphatase activity
RQCS_RS10655	COG1192	Involved in chromosome partitioning
RQCS_RS10665	COG0513	Belongs to the DEAD box helicase family
RQCS_RS10700	COG2186	Transcriptional regulator
RQCS_RS10715	COG2146	nitrite reductase [NAD(P)H] activity
RQCS_RS10715	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RQCS_RS10720	COG2146	nitrite reductase [NAD(P)H] activity
RQCS_RS10720	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RQCS_RS10765	COG0596	Alpha beta hydrolase
RQCS_RS10770	COG0210	DNA helicase
RQCS_RS10810	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
RQCS_RS10825	COG3480	Lon protease (S16) C-terminal proteolytic domain
RQCS_RS10835	COG1615	UPF0182 protein
RQCS_RS10840	COG1388	LysM domain
RQCS_RS10865	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RQCS_RS10885	COG0402	S-adenosylhomocysteine deaminase activity
RQCS_RS10890	COG0318	PFAM AMP-dependent synthetase and ligase
RQCS_RS10895	COG1960	acyl-CoA dehydrogenase activity
RQCS_RS10910	COG2197	response regulator
RQCS_RS10915	COG2132	Multicopper oxidase
RQCS_RS10920	COG0483	inositol monophosphate 1-phosphatase activity
RQCS_RS10930	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
RQCS_RS10935	COG0668	transmembrane transport
RQCS_RS10945	COG2884	Cell division ATP-binding protein ftsE
RQCS_RS10950	COG2177	Part of the ABC transporter FtsEX involved in
RQCS_RS10955	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
RQCS_RS10975	COG0702	epimerase
RQCS_RS10985	COG3119	arylsulfatase activity
RQCS_RS11015	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
RQCS_RS11020	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
RQCS_RS11030	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
RQCS_RS11035	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
RQCS_RS11070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RQCS_RS11085	COG0778	Nitroreductase
RQCS_RS11090	COG0513	Belongs to the DEAD box helicase family
RQCS_RS11100	COG0315	cyclic pyranopterin monophosphate synthase activity
RQCS_RS11100	COG0521	Mo-molybdopterin cofactor biosynthetic process
RQCS_RS11110	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
RQCS_RS11125	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
RQCS_RS11140	COG1309	transcriptional regulator
RQCS_RS11160	COG1780	Probably involved in ribonucleotide reductase function
RQCS_RS11165	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RQCS_RS11195	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RQCS_RS11200	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
RQCS_RS11225	COG1119	ATPase activity
RQCS_RS11240	COG2226	methyltransferase
RQCS_RS11255	COG0110	maltose O-acetyltransferase activity
RQCS_RS11275	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
RQCS_RS11285	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
RQCS_RS11305	COG0482	sulfurtransferase activity
RQCS_RS11315	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
RQCS_RS11330	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
RQCS_RS11335	COG0154	amidase activity
RQCS_RS11350	COG4585	Histidine kinase
RQCS_RS11355	COG2197	response regulator
RQCS_RS11360	COG0205	6-phosphofructokinase activity
RQCS_RS11365	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
RQCS_RS11380	COG2259	Doxx family
RQCS_RS11385	COG0531	amino acid
RQCS_RS11390	COG0129	dihydroxy-acid dehydratase activity
RQCS_RS11405	COG0440	acetolactate synthase activity
RQCS_RS11410	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
RQCS_RS11420	COG0473	3-isopropylmalate dehydrogenase activity
RQCS_RS11425	COG0179	Fumarylacetoacetate (FAA) hydrolase
RQCS_RS11430	COG3239	Fatty acid desaturase
RQCS_RS11435	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
RQCS_RS11460	COG1414	Transcriptional regulator
RQCS_RS11465	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
RQCS_RS11470	COG0066	3-isopropylmalate dehydratase activity
RQCS_RS11485	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
RQCS_RS11490	COG1920	GTP binding
RQCS_RS11495	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
RQCS_RS11500	COG0626	cystathionine gamma-synthase activity
RQCS_RS11505	COG1181	Belongs to the D-alanine--D-alanine ligase family
RQCS_RS11525	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
RQCS_RS11535	COG0227	Belongs to the bacterial ribosomal protein bL28 family
RQCS_RS11540	COG1461	Dihydroxyacetone kinase
RQCS_RS11545	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
RQCS_RS11550	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
RQCS_RS11555	COG0742	ribosomal rna small subunit methyltransferase
RQCS_RS11560	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
RQCS_RS11575	COG0333	Belongs to the bacterial ribosomal protein bL32 family
RQCS_RS11580	COG0571	ribonuclease III activity
RQCS_RS11585	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
RQCS_RS11600	COG1254	Belongs to the acylphosphatase family
RQCS_RS11605	COG1196	nuclear chromosome segregation
RQCS_RS11625	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
RQCS_RS11640	COG0228	four-way junction DNA binding
RQCS_RS11650	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
RQCS_RS11655	COG0336	Belongs to the RNA methyltransferase TrmD family
RQCS_RS11680	COG0463	Glycosyl transferase, family 2
RQCS_RS11685	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
RQCS_RS11705	COG0335	large ribosomal subunit rRNA binding
RQCS_RS11710	COG0681	Belongs to the peptidase S26 family
RQCS_RS11715	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
RQCS_RS11725	COG1690	Belongs to the RtcB family
RQCS_RS11750	COG0792	nuclease activity
RQCS_RS11775	COG2814	Major facilitator Superfamily
RQCS_RS11795	COG0052	Belongs to the universal ribosomal protein uS2 family
RQCS_RS11800	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
RQCS_RS11805	COG0528	UMP kinase activity
RQCS_RS11810	COG0233	cytoplasmic translational termination
RQCS_RS11815	COG0575	Belongs to the CDS family
RQCS_RS11820	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
RQCS_RS11835	COG0820	rRNA (adenine-C2-)-methyltransferase activity
RQCS_RS11845	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
RQCS_RS11850	COG0750	zinc metalloprotease
RQCS_RS11870	COG2197	response regulator
RQCS_RS11875	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RQCS_RS11910	COG2188	Transcriptional regulator
RQCS_RS11940	COG1760	l-serine dehydratase
RQCS_RS11970	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
RQCS_RS12005	COG2207	Transcriptional regulator
RQCS_RS12010	COG2076	Multidrug Resistance protein
RQCS_RS12030	COG1492	cobalamin metabolic process
RQCS_RS12050	COG0384	phenazine biosynthesis protein PhzF
RQCS_RS12055	COG3467	pyridoxamine 5'-phosphate
RQCS_RS12075	COG0579	oxidoreductase
RQCS_RS12105	COG1648	precorrin-2 dehydrogenase activity
RQCS_RS12105	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
RQCS_RS12115	COG0517	IMP dehydrogenase activity
RQCS_RS12120	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
RQCS_RS12125	COG3022	response to hydroperoxide
RQCS_RS12130	COG0442	prolyl-tRNA aminoacylation
RQCS_RS12135	COG4122	O-methyltransferase activity
RQCS_RS12165	COG0697	spore germination
RQCS_RS12170	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS12185	COG0477	Major facilitator Superfamily
RQCS_RS12200	COG0779	Required for maturation of 30S ribosomal subunits
RQCS_RS12215	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
RQCS_RS12215	COG0481	GTPase activity
RQCS_RS12225	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
RQCS_RS12230	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
RQCS_RS12240	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
RQCS_RS12250	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
RQCS_RS12270	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
RQCS_RS12275	COG1185	polyribonucleotide nucleotidyltransferase activity
RQCS_RS12295	COG0375	protein maturation
RQCS_RS12315	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
RQCS_RS12345	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
RQCS_RS12350	COG0298	carbon dioxide binding
RQCS_RS12355	COG0409	Hydrogenase expression formation protein
RQCS_RS12360	COG0309	Hydrogenase expression formation protein (HypE)
RQCS_RS12400	COG0657	acetylesterase activity
RQCS_RS12405	COG3835	regulator
RQCS_RS12430	COG2365	Tyrosine phosphatase family
RQCS_RS12450	COG0789	Transcriptional regulator
RQCS_RS12460	COG0095	Lipoate-protein ligase
RQCS_RS12490	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
RQCS_RS12520	COG3433	isochorismatase activity
RQCS_RS12520	COG1535	isochorismatase
RQCS_RS12525	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS12530	COG1021	2,3-dihydroxybenzoate-AMP ligase
RQCS_RS12535	COG1535	isochorismatase
RQCS_RS12535	COG3433	isochorismatase activity
RQCS_RS12545	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RQCS_RS12550	COG4592	Periplasmic binding protein
RQCS_RS12560	COG2375	cellular response to nickel ion
RQCS_RS12580	COG1131	(ABC) transporter
RQCS_RS12625	COG0713	ATP synthesis coupled electron transport
RQCS_RS12635	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RQCS_RS12640	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
RQCS_RS12645	COG1034	ATP synthesis coupled electron transport
RQCS_RS12660	COG0649	NAD binding
RQCS_RS12670	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RQCS_RS12705	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
RQCS_RS12730	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
RQCS_RS12740	COG1058	Belongs to the CinA family
RQCS_RS12740	COG1546	Belongs to the CinA family
RQCS_RS12745	COG1396	sequence-specific DNA binding
RQCS_RS12750	COG1842	Phage shock protein A
RQCS_RS12760	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
RQCS_RS12765	COG1122	ATPase activity
RQCS_RS12770	COG1268	BioY protein
RQCS_RS12805	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
RQCS_RS12810	COG2137	regulation of response to DNA damage stimulus
RQCS_RS12815	COG0765	amino acid transport
RQCS_RS12820	COG0765	amino acid transport
RQCS_RS12825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RQCS_RS12830	COG1126	abc transporter atp-binding protein
RQCS_RS12835	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RQCS_RS12845	COG1196	nuclear chromosome segregation
RQCS_RS12855	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
RQCS_RS12865	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
RQCS_RS12870	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
RQCS_RS12880	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
RQCS_RS12885	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
RQCS_RS12890	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RQCS_RS12890	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RQCS_RS12890	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
RQCS_RS12895	COG1105	Belongs to the carbohydrate kinase PfkB family
RQCS_RS12900	COG1349	DNA-binding transcription factor activity
RQCS_RS12905	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
RQCS_RS12910	COG2233	PERMEase
RQCS_RS12915	COG1960	acyl-CoA dehydrogenase activity
RQCS_RS12925	COG1388	LysM domain
RQCS_RS12930	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
RQCS_RS12935	COG1643	Atp-dependent helicase
RQCS_RS12970	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RQCS_RS12975	COG0450	alkyl hydroperoxide reductase
RQCS_RS12985	COG0277	FAD linked oxidase domain protein
RQCS_RS13035	COG0123	including yeast histone deacetylase and acetoin utilization protein
RQCS_RS13040	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RQCS_RS13040	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RQCS_RS13050	COG2813	Specifically methylates the guanine in position
RQCS_RS13090	COG0475	glutathione-regulated potassium exporter activity
RQCS_RS13095	COG2365	Tyrosine phosphatase family
RQCS_RS13110	COG0483	inositol monophosphate 1-phosphatase activity
RQCS_RS13130	COG0756	dUTP diphosphatase activity
RQCS_RS13165	COG0569	domain protein
RQCS_RS13170	COG0531	amino acid
RQCS_RS13175	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
RQCS_RS13185	COG0477	Major facilitator Superfamily
RQCS_RS13195	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
RQCS_RS13195	COG2066	Belongs to the glutaminase family
RQCS_RS13200	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
RQCS_RS13205	COG0477	Major facilitator Superfamily
RQCS_RS13225	COG1024	Enoyl-CoA hydratase
RQCS_RS13225	COG1250	3-hydroxyacyl-CoA dehydrogenase
RQCS_RS13230	COG0183	Belongs to the thiolase family
RQCS_RS13250	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
RQCS_RS13285	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
RQCS_RS13315	COG2223	nitrite transmembrane transporter activity
RQCS_RS13320	COG2723	6-phospho-beta-galactosidase activity
RQCS_RS13365	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
RQCS_RS13380	COG1560	Kdo2-lipid A biosynthetic process
RQCS_RS13385	COG0438	transferase activity, transferring glycosyl groups
RQCS_RS13390	COG1051	belongs to the nudix hydrolase family
RQCS_RS13395	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
RQCS_RS13415	COG1946	Acyl-CoA thioesterase
RQCS_RS13425	COG1946	Acyl-CoA thioesterase
RQCS_RS13435	COG2197	response regulator
RQCS_RS13440	COG4585	Histidine kinase
RQCS_RS13460	COG2188	Transcriptional regulator
RQCS_RS13465	COG0217	transcriptional regulatory protein
RQCS_RS13470	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
RQCS_RS13475	COG0632	four-way junction helicase activity
RQCS_RS13480	COG2255	four-way junction helicase activity
RQCS_RS13495	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RQCS_RS13500	COG0747	negative chemotaxis
RQCS_RS13505	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
RQCS_RS13510	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
RQCS_RS13515	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
RQCS_RS13520	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
RQCS_RS13530	COG0124	histidyl-tRNA synthetase
RQCS_RS13540	COG0039	L-malate dehydrogenase activity
RQCS_RS13565	COG1131	(ABC) transporter
RQCS_RS13585	COG1053	succinate dehydrogenase
RQCS_RS13590	COG0488	(ABC) transporter
RQCS_RS13600	COG1652	LysM domain
RQCS_RS13630	COG2184	nucleotidyltransferase activity
RQCS_RS13660	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
RQCS_RS13690	COG0662	Cupin 2, conserved barrel domain protein
RQCS_RS13710	COG1309	transcriptional regulator
RQCS_RS13715	COG2824	Alkylphosphonate utilization operon protein PhnA
RQCS_RS13750	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
RQCS_RS13775	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
RQCS_RS13780	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
RQCS_RS13790	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
RQCS_RS13805	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
RQCS_RS13810	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
RQCS_RS13815	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
RQCS_RS13835	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
RQCS_RS13840	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RQCS_RS13850	COG0540	Belongs to the ATCase OTCase family
RQCS_RS13865	COG0505	Belongs to the CarA family
RQCS_RS13875	COG0284	orotidine-5'-phosphate decarboxylase activity
RQCS_RS13880	COG1051	belongs to the nudix hydrolase family
RQCS_RS13890	COG0194	GDP metabolic process
RQCS_RS13895	COG1758	RNA polymerase activity
RQCS_RS13905	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
RQCS_RS13930	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
RQCS_RS13960	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RQCS_RS13960	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RQCS_RS13975	COG0322	excinuclease ABC activity
RQCS_RS13980	COG1660	Displays ATPase and GTPase activities
RQCS_RS13995	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
RQCS_RS14000	COG0126	phosphoglycerate kinase activity
RQCS_RS14005	COG0149	triose-phosphate isomerase activity
RQCS_RS14010	COG2365	Tyrosine phosphatase family
RQCS_RS14020	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
RQCS_RS14025	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS14045	COG1129	ABC transporter
RQCS_RS14055	COG4221	oxidoreductase activity
RQCS_RS14075	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
RQCS_RS14085	COG0109	protoheme IX farnesyltransferase activity
RQCS_RS14105	COG4974	Belongs to the 'phage' integrase family
RQCS_RS14115	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS14145	COG0318	PFAM AMP-dependent synthetase and ligase
RQCS_RS14160	COG0183	Belongs to the thiolase family
RQCS_RS14165	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS14170	COG1024	Enoyl-CoA hydratase
RQCS_RS14220	COG2267	carboxylic ester hydrolase activity
RQCS_RS14225	COG4948	Mandelate Racemase Muconate Lactonizing
RQCS_RS14310	COG0396	ATPase activity
RQCS_RS14320	COG0822	iron-sulfur transferase activity
RQCS_RS14335	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
RQCS_RS14350	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS14355	COG0488	(ABC) transporter
RQCS_RS14360	COG1309	transcriptional regulator
RQCS_RS14365	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
RQCS_RS14375	COG0791	NLP P60 protein
RQCS_RS14375	COG3883	PFAM NLP P60 protein
RQCS_RS14380	COG0714	Associated with various cellular activities
RQCS_RS14390	COG2304	oxidoreductase activity
RQCS_RS14405	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
RQCS_RS14425	COG1024	Enoyl-CoA hydratase
RQCS_RS14425	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
RQCS_RS14480	COG0730	response to heat
RQCS_RS14505	COG1253	flavin adenine dinucleotide binding
RQCS_RS14510	COG1253	flavin adenine dinucleotide binding
RQCS_RS14520	COG0697	spore germination
RQCS_RS14525	COG0513	Belongs to the DEAD box helicase family
RQCS_RS14530	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
RQCS_RS14535	COG0513	Belongs to the DEAD box helicase family
RQCS_RS14550	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
RQCS_RS14555	COG1120	ATPase activity
RQCS_RS14560	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RQCS_RS14565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RQCS_RS14580	COG1252	NADH dehydrogenase
RQCS_RS14585	COG0640	Transcriptional regulator
RQCS_RS14615	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
RQCS_RS14625	COG3300	MHYT domain
RQCS_RS14625	COG5001	Diguanylate cyclase
RQCS_RS14690	COG2197	response regulator
RQCS_RS14695	COG4585	Histidine kinase
RQCS_RS14715	COG1090	epimerase
RQCS_RS14775	COG4762	Protein conserved in bacteria
RQCS_RS14790	COG2205	protein histidine kinase activity
RQCS_RS14805	COG2242	protein methyltransferase activity
RQCS_RS14805	COG2241	protein methyltransferase activity
RQCS_RS14810	COG0300	oxidoreductase activity
RQCS_RS14845	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
RQCS_RS14850	COG2378	regulation of single-species biofilm formation
RQCS_RS14860	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
RQCS_RS14875	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
RQCS_RS14900	COG1222	aaa ATPase
RQCS_RS14915	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
RQCS_RS14925	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
RQCS_RS14930	COG0140	phosphoribosyl-ATP diphosphatase activity
RQCS_RS14940	COG1054	Belongs to the UPF0176 family
RQCS_RS14950	COG1410	methionine synthase
RQCS_RS14950	COG0646	methionine synthase
RQCS_RS14985	COG0215	cysteine-tRNA ligase activity
RQCS_RS14990	COG2409	Drug exporters of the RND superfamily
RQCS_RS15015	COG1968	undecaprenyl-diphosphatase activity
RQCS_RS15020	COG0667	Aldo Keto reductase
RQCS_RS15035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RQCS_RS15040	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
RQCS_RS15060	COG0167	dihydroorotate dehydrogenase activity
RQCS_RS15070	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RQCS_RS15095	COG3268	Saccharopine dehydrogenase
RQCS_RS15100	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
RQCS_RS15110	COG1408	metallophosphoesterase
RQCS_RS15135	COG1716	ATPase activity
RQCS_RS15170	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
RQCS_RS15180	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
RQCS_RS15190	COG0351	phosphomethylpyrimidine kinase
RQCS_RS15220	COG0444	Belongs to the ABC transporter superfamily
RQCS_RS15225	COG4608	Belongs to the ABC transporter superfamily
RQCS_RS15230	COG0747	negative chemotaxis
RQCS_RS15240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RQCS_RS15270	COG1160	GTP binding
RQCS_RS15275	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
RQCS_RS15285	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
RQCS_RS15290	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
RQCS_RS15305	COG0494	nUDIX hydrolase
RQCS_RS15310	COG0504	CTP synthase activity
RQCS_RS15330	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
RQCS_RS15345	COG0647	UMP catabolic process
RQCS_RS15370	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
RQCS_RS15375	COG2094	Belongs to the DNA glycosylase MPG family
RQCS_RS15380	COG1131	(ABC) transporter
RQCS_RS15395	COG2835	tetraacyldisaccharide 4'-kinase activity
RQCS_RS15405	COG0165	Argininosuccinate lyase
RQCS_RS15410	COG0137	argininosuccinate synthase activity
RQCS_RS15415	COG1438	arginine binding
RQCS_RS15420	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
RQCS_RS15425	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
RQCS_RS15430	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
RQCS_RS15435	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
RQCS_RS15440	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
RQCS_RS15450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RQCS_RS15455	COG0385	Bile acid
RQCS_RS15460	COG2072	flavoprotein involved in K transport
RQCS_RS15470	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RQCS_RS15470	COG0072	phenylalanine-tRNA ligase activity
RQCS_RS15475	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
RQCS_RS15485	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
RQCS_RS15490	COG0291	Belongs to the bacterial ribosomal protein bL35 family
RQCS_RS15525	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RQCS_RS15570	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
RQCS_RS15570	COG0237	dephospho-CoA kinase activity
RQCS_RS15580	COG0539	negative regulation of cytoplasmic translation
RQCS_RS15585	COG2226	methyltransferase
RQCS_RS15585	COG1073	alpha beta
RQCS_RS15600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RQCS_RS15605	COG0473	3-isopropylmalate dehydrogenase activity
RQCS_RS15625	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RQCS_RS15635	COG1172	Belongs to the binding-protein-dependent transport system permease family
RQCS_RS15675	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
RQCS_RS15685	COG1946	Acyl-CoA thioesterase
RQCS_RS15700	COG0067	glutamate synthase
RQCS_RS15700	COG0069	glutamate synthase activity
RQCS_RS15700	COG0070	glutamate synthase
RQCS_RS15715	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
RQCS_RS15720	COG0159	tryptophan synthase activity
RQCS_RS15730	COG0134	indole-3-glycerol-phosphate synthase activity
RQCS_RS15740	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
RQCS_RS15750	COG3384	dioxygenase
RQCS_RS15760	COG1053	succinate dehydrogenase
RQCS_RS15785	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
RQCS_RS15810	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
RQCS_RS15820	COG2124	cytochrome p450
RQCS_RS15865	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS15890	COG1053	succinate dehydrogenase
RQCS_RS15915	COG1529	Aldehyde oxidase and xanthine dehydrogenase
RQCS_RS15915	COG2080	2 iron, 2 sulfur cluster binding
RQCS_RS15930	COG2132	Multicopper oxidase
RQCS_RS15945	COG0640	Transcriptional regulator
RQCS_RS15950	COG0748	coenzyme F420 binding
RQCS_RS15970	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
RQCS_RS15980	COG2072	flavoprotein involved in K transport
RQCS_RS15990	COG0107	imidazoleglycerol-phosphate synthase activity
RQCS_RS15995	COG0483	inositol monophosphate 1-phosphatase activity
RQCS_RS16000	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
RQCS_RS16010	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
RQCS_RS16025	COG0131	Imidazoleglycerol-phosphate dehydratase
RQCS_RS16035	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
RQCS_RS16080	COG1280	lysine exporter protein (LysE YggA)
RQCS_RS16095	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
RQCS_RS16120	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RQCS_RS16120	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RQCS_RS16130	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RQCS_RS16135	COG1510	regulation of RNA biosynthetic process
RQCS_RS16145	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
RQCS_RS16160	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RQCS_RS16200	COG4221	oxidoreductase activity
RQCS_RS16215	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
RQCS_RS16285	COG2199	diguanylate cyclase activity
RQCS_RS16290	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
RQCS_RS16300	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RQCS_RS16315	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS16320	COG0604	alcohol dehydrogenase
RQCS_RS16320	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS16320	COG3321	synthase
RQCS_RS16330	COG1309	transcriptional regulator
RQCS_RS16335	COG5006	permease, DMT superfamily
RQCS_RS16360	COG0477	Major facilitator Superfamily
RQCS_RS16380	COG0798	PFAM Bile acid sodium symporter
RQCS_RS16385	COG0640	Transcriptional regulator
RQCS_RS16405	COG0477	Major facilitator Superfamily
RQCS_RS16420	COG0028	Belongs to the TPP enzyme family
RQCS_RS16455	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
RQCS_RS16470	COG0076	glutamate decarboxylase activity
RQCS_RS16490	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
RQCS_RS16500	COG3599	regulation of cell shape
RQCS_RS16510	COG1799	cell septum assembly
RQCS_RS16520	COG1496	oxidoreductase activity
RQCS_RS16525	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
RQCS_RS16530	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
RQCS_RS16535	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
RQCS_RS16540	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
RQCS_RS16550	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
RQCS_RS16570	COG0768	penicillin binding
RQCS_RS16580	COG0275	rRNA processing
RQCS_RS16585	COG2001	Belongs to the MraZ family
RQCS_RS16620	COG0142	geranyltranstransferase activity
RQCS_RS16655	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
RQCS_RS16670	COG1940	carbohydrate kinase activity
RQCS_RS16680	COG0003	Pfam Anion-transporting ATPase
RQCS_RS16690	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
RQCS_RS16715	COG0791	NLP P60 protein
RQCS_RS16730	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
RQCS_RS16740	COG1845	cytochrome c oxidase, subunit III
RQCS_RS16760	COG2329	Antibiotic biosynthesis monooxygenase
RQCS_RS16775	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
RQCS_RS16785	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RQCS_RS16805	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
RQCS_RS16810	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
RQCS_RS16815	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
RQCS_RS16830	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RQCS_RS16835	COG0404	The glycine cleavage system catalyzes the degradation of glycine
RQCS_RS16840	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
RQCS_RS16860	COG0321	lipoyl(octanoyl) transferase activity
RQCS_RS16865	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
RQCS_RS16880	COG0174	glutamine synthetase
RQCS_RS16895	COG2267	carboxylic ester hydrolase activity
RQCS_RS16960	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
RQCS_RS17000	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
RQCS_RS17005	COG0174	glutamine synthetase
RQCS_RS17015	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
RQCS_RS17050	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
RQCS_RS17065	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
RQCS_RS17065	COG3323	Protein of unknown function (DUF1653)
RQCS_RS17090	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
RQCS_RS17120	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
RQCS_RS17135	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RQCS_RS17140	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
RQCS_RS17170	COG2197	response regulator
RQCS_RS17175	COG4585	Histidine kinase
RQCS_RS17180	COG2409	Drug exporters of the RND superfamily
RQCS_RS17185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RQCS_RS17190	COG3842	ATPase activity
RQCS_RS17195	COG0395	ABC-type sugar transport system, permease component
RQCS_RS17215	COG1063	alcohol dehydrogenase
RQCS_RS17265	COG0232	Belongs to the dGTPase family. Type 2 subfamily
RQCS_RS17280	COG0463	Glycosyl transferase, family 2
RQCS_RS17305	COG0423	glycine-tRNA ligase activity
RQCS_RS17325	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
RQCS_RS17330	COG1381	Involved in DNA repair and RecF pathway recombination
RQCS_RS17355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RQCS_RS17360	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
RQCS_RS17370	COG1063	alcohol dehydrogenase
RQCS_RS17385	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
RQCS_RS17390	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
RQCS_RS17395	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
RQCS_RS17425	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
RQCS_RS17440	COG0477	Major facilitator Superfamily
RQCS_RS17450	COG1376	ErfK ybiS ycfS ynhG family protein
RQCS_RS17460	COG0484	heat shock protein binding
RQCS_RS17465	COG1420	regulation of RNA biosynthetic process
RQCS_RS17490	COG0175	sulfate reduction
RQCS_RS17520	COG3842	ATPase activity
RQCS_RS17525	COG4208	sulfate ABC transporter
RQCS_RS17545	COG3387	PFAM Glycoside hydrolase 15-related
RQCS_RS17550	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RQCS_RS17555	COG2070	2-Nitropropane dioxygenase
RQCS_RS17570	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
RQCS_RS17575	COG1305	Transglutaminase-like
RQCS_RS17590	COG0268	Binds directly to 16S ribosomal RNA
RQCS_RS17600	COG0658	competence protein
RQCS_RS17600	COG2333	competence protein COMEC
RQCS_RS17615	COG2755	lipolytic protein G-D-S-L family
RQCS_RS17620	COG0406	alpha-ribazole phosphatase activity
RQCS_RS17630	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
RQCS_RS17640	COG0542	response to heat
RQCS_RS17645	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
RQCS_RS17660	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RQCS_RS17670	COG0514	ATP-dependent DNA helicase (RecQ)
RQCS_RS17675	COG0456	acetyltransferase
RQCS_RS17680	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
RQCS_RS17685	COG1917	Cupin 2, conserved barrel domain protein
RQCS_RS17690	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RQCS_RS17710	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
RQCS_RS17715	COG0211	Belongs to the bacterial ribosomal protein bL27 family
RQCS_RS17720	COG0261	This protein binds to 23S rRNA in the presence of protein L20
RQCS_RS17725	COG1530	ribonuclease E activity
RQCS_RS17725	COG1530	ribonuclease E activity
RQCS_RS17730	COG0105	UTP biosynthetic process
RQCS_RS17740	COG0285	dihydrofolate synthase activity
RQCS_RS17745	COG0525	valine-tRNA ligase activity
RQCS_RS17755	COG1506	peptidase
RQCS_RS17755	COG4946	Tricorn protease homolog
RQCS_RS17755	COG0823	Involved in the tonB-independent uptake of proteins
RQCS_RS17775	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
RQCS_RS17780	COG3185	4-Hydroxyphenylpyruvate dioxygenase
RQCS_RS17780	COG1082	Xylose isomerase domain protein TIM barrel
RQCS_RS17785	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
RQCS_RS17790	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
RQCS_RS17795	COG1309	transcriptional regulator
RQCS_RS17805	COG0477	Major facilitator Superfamily
RQCS_RS17810	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
RQCS_RS17815	COG0740	serine-type endopeptidase activity
RQCS_RS17820	COG0740	serine-type endopeptidase activity
RQCS_RS17825	COG0544	peptidyl-prolyl cis-trans isomerase activity
RQCS_RS17860	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
RQCS_RS17875	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
RQCS_RS17890	COG2346	COG2346, Truncated hemoglobins
RQCS_RS17915	COG2902	Dehydrogenase
RQCS_RS17935	COG1132	(ABC) transporter
RQCS_RS17940	COG1846	Transcriptional regulator
RQCS_RS17950	COG3336	cytochrome c oxidase
RQCS_RS17975	COG3764	Sortase (surface protein transpeptidase)
RQCS_RS17995	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
RQCS_RS18035	COG0596	Alpha beta hydrolase
RQCS_RS18055	COG0446	pyridine nucleotide-disulphide oxidoreductase
RQCS_RS18055	COG1902	pentaerythritol trinitrate reductase activity
RQCS_RS18060	COG0300	oxidoreductase activity
RQCS_RS18075	COG0433	COG0433 Predicted ATPase
RQCS_RS18080	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
RQCS_RS18090	COG0789	Transcriptional regulator
RQCS_RS18100	COG1376	ErfK ybiS ycfS ynhG family protein
RQCS_RS18140	COG0736	holo-[acyl-carrier-protein] synthase activity
RQCS_RS18175	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
RQCS_RS18180	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
RQCS_RS18185	COG1234	tRNA 3'-trailer cleavage
RQCS_RS18195	COG3191	aminopeptidase activity
RQCS_RS18205	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
RQCS_RS18210	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
RQCS_RS18215	COG1335	isochorismatase
RQCS_RS18225	COG0058	SHG alpha-glucan phosphorylase activity
RQCS_RS18230	COG0366	Alpha amylase catalytic
RQCS_RS18235	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
RQCS_RS18255	COG0183	Belongs to the thiolase family
RQCS_RS18270	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
RQCS_RS18300	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
RQCS_RS18315	COG0355	proton-transporting ATP synthase activity, rotational mechanism
RQCS_RS18320	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
RQCS_RS18325	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
RQCS_RS18330	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
RQCS_RS18335	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
RQCS_RS18340	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
RQCS_RS18345	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
RQCS_RS18350	COG0356	it plays a direct role in the translocation of protons across the membrane
RQCS_RS18360	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
RQCS_RS18365	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
RQCS_RS18375	COG2890	protein-(glutamine-N5) methyltransferase activity
RQCS_RS18380	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
RQCS_RS18385	COG0254	rRNA binding
RQCS_RS18395	COG0083	homoserine kinase activity
RQCS_RS18400	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
RQCS_RS18405	COG0460	homoserine dehydrogenase
RQCS_RS18410	COG0019	diaminopimelate decarboxylase activity
RQCS_RS18415	COG0018	arginyl-trna synthetase
RQCS_RS18430	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
RQCS_RS18445	COG0477	Major facilitator Superfamily
RQCS_RS18465	COG0686	Belongs to the AlaDH PNT family
RQCS_RS18475	COG1218	3'(2'),5'-bisphosphate nucleotidase
RQCS_RS18510	COG0596	Alpha beta hydrolase
RQCS_RS18535	COG2814	Major facilitator Superfamily
RQCS_RS18560	COG1024	Enoyl-CoA hydratase
RQCS_RS18565	COG1960	acyl-CoA dehydrogenase activity
RQCS_RS18580	COG0363	glucosamine-6-phosphate deaminase activity
RQCS_RS18585	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
RQCS_RS18590	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
RQCS_RS18600	COG1263	PTS System
RQCS_RS18605	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RQCS_RS18610	COG2190	(PTS) system
RQCS_RS18615	COG2188	Transcriptional regulator
RQCS_RS18620	COG4279	zinc finger
RQCS_RS18625	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
RQCS_RS18630	COG0604	alcohol dehydrogenase
RQCS_RS18630	COG3321	synthase
RQCS_RS18650	COG1228	amidohydrolase
RQCS_RS18665	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
RQCS_RS18680	COG1280	lysine exporter protein (LysE YggA)
RQCS_RS18690	COG3135	benzoate transporter
RQCS_RS18710	COG0022	dehydrogenase e1 component
RQCS_RS18715	COG0508	dehydrogenase complex catalyzes the overall conversion of
RQCS_RS18720	COG2223	nitrite transmembrane transporter activity
RQCS_RS18745	COG0318	PFAM AMP-dependent synthetase and ligase
RQCS_RS18780	COG0351	phosphomethylpyrimidine kinase
RQCS_RS18780	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
RQCS_RS18780	COG0352	thiamine-phosphate diphosphorylase activity
RQCS_RS18785	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RQCS_RS18790	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RQCS_RS18820	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
RQCS_RS18825	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
RQCS_RS18830	COG1522	sequence-specific DNA binding
RQCS_RS18875	COG1063	alcohol dehydrogenase
RQCS_RS18885	COG3976	FMN-binding domain protein
RQCS_RS18885	COG1053	succinate dehydrogenase
RQCS_RS18900	COG1022	Amp-dependent synthetase and ligase
RQCS_RS18910	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RQCS_RS18945	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
RQCS_RS18955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RQCS_RS18960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RQCS_RS18970	COG0531	amino acid
RQCS_RS18975	COG3457	Alanine racemase
RQCS_RS19005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RQCS_RS19010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RQCS_RS19015	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
RQCS_RS19020	COG1823	symporter activity
RQCS_RS19035	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
RQCS_RS19085	COG0439	Biotin carboxylase
RQCS_RS19105	COG0667	Aldo Keto reductase
RQCS_RS19130	COG1960	acyl-CoA dehydrogenase activity
RQCS_RS19140	COG0577	efflux transmembrane transporter activity
RQCS_RS19145	COG1136	(ABC) transporter
RQCS_RS19145	COG0577	efflux transmembrane transporter activity
RQCS_RS19150	COG0318	PFAM AMP-dependent synthetase and ligase
RQCS_RS19155	COG3012	SEC-C Motif Domain Protein
RQCS_RS19165	COG1132	(ABC) transporter
RQCS_RS19175	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RQCS_RS19200	COG0277	FAD linked oxidase domain protein
RQCS_RS19210	COG1335	isochorismatase
RQCS_RS19215	COG2267	carboxylic ester hydrolase activity
RQCS_RS19240	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
RQCS_RS19245	COG1024	Enoyl-CoA hydratase
RQCS_RS19250	COG0318	PFAM AMP-dependent synthetase and ligase
RQCS_RS19260	COG0277	FAD linked oxidase domain protein
RQCS_RS19280	COG0435	Glutathione S-transferase
RQCS_RS19295	COG1131	(ABC) transporter
RQCS_RS19305	COG1132	(ABC) transporter
RQCS_RS19310	COG0508	dehydrogenase complex catalyzes the overall conversion of
RQCS_RS19310	COG0567	Dehydrogenase, E1 component
RQCS_RS19315	COG1309	transcriptional regulator
RQCS_RS19345	COG1125	glycine betaine transport
RQCS_RS19345	COG0517	IMP dehydrogenase activity
RQCS_RS19350	COG1174	glycine betaine transport
RQCS_RS19370	COG2095	MarC family integral membrane protein
RQCS_RS19380	COG0598	Magnesium transport protein CorA
RQCS_RS19445	COG2301	Belongs to the HpcH HpaI aldolase family
RQCS_RS19450	COG2239	Acts as a magnesium transporter
RQCS_RS19480	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RQCS_RS19485	COG5662	AntiSigma factor
RQCS_RS19500	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
RQCS_RS19505	COG0297	glycogen (starch) synthase activity
RQCS_RS19510	COG2226	methyltransferase
RQCS_RS19520	COG0519	Catalyzes the synthesis of GMP from XMP
RQCS_RS19530	COG0463	Glycosyl transferase, family 2
RQCS_RS19535	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
RQCS_RS19540	COG0318	PFAM AMP-dependent synthetase and ligase
RQCS_RS19545	COG1611	Belongs to the LOG family
RQCS_RS19550	COG1611	Belongs to the LOG family
RQCS_RS19560	COG2171	N-acyltransferase activity
RQCS_RS19565	COG1113	amino acid transport
RQCS_RS19575	COG1131	(ABC) transporter
RQCS_RS19615	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
RQCS_RS19650	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
RQCS_RS19655	COG0747	negative chemotaxis
RQCS_RS19675	COG2154	pterin-4-alpha-carbinolamine dehydratase
RQCS_RS19695	COG2814	Major facilitator Superfamily
RQCS_RS19705	COG3757	hydrolase, family 25
RQCS_RS19720	COG0402	S-adenosylhomocysteine deaminase activity
RQCS_RS19755	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
RQCS_RS19755	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
RQCS_RS19800	COG0584	glycerophosphoryl diester phosphodiesterase
RQCS_RS19815	COG0012	GTP binding
RQCS_RS19825	COG0069	glutamate synthase activity
RQCS_RS19830	COG1966	Carbon starvation protein
RQCS_RS19850	COG0419	ATPase involved in DNA repair
RQCS_RS19855	COG0420	3'-5' exonuclease activity
RQCS_RS19865	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
RQCS_RS19875	COG1570	exodeoxyribonuclease VII activity
RQCS_RS19915	COG0477	Major facilitator Superfamily
RQCS_RS19925	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
RQCS_RS19935	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
RQCS_RS19940	COG2197	response regulator
RQCS_RS19950	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
RQCS_RS19960	COG1072	(Pantothenic acid kinase))
RQCS_RS19965	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
RQCS_RS19975	COG1331	Highly conserved protein containing a thioredoxin domain
RQCS_RS19985	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
RQCS_RS19995	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
RQCS_RS20000	COG3883	PFAM NLP P60 protein
RQCS_RS20000	COG0791	NLP P60 protein
RQCS_RS20015	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
RQCS_RS20030	COG2755	lipolytic protein G-D-S-L family
RQCS_RS20035	COG0183	Belongs to the thiolase family
RQCS_RS20040	COG1024	Enoyl-CoA hydratase
RQCS_RS20050	COG2813	Specifically methylates the guanine in position
RQCS_RS20065	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS20075	COG5001	Diguanylate cyclase
RQCS_RS20465	COG4974	Belongs to the 'phage' integrase family
RQCS_RS20490	COG0148	phosphopyruvate hydratase activity
RQCS_RS20500	COG0672	)-iron permease
RQCS_RS20510	COG2837	iron assimilation
RQCS_RS20535	COG0489	protein tyrosine kinase activity
RQCS_RS20565	COG0297	glycogen (starch) synthase activity
RQCS_RS20570	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
RQCS_RS20575	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RQCS_RS20585	COG0438	transferase activity, transferring glycosyl groups
RQCS_RS20600	COG3956	TIGRFAM MazG family protein
RQCS_RS20620	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
RQCS_RS20630	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RQCS_RS20635	COG0736	holo-[acyl-carrier-protein] synthase activity
RQCS_RS20645	COG1309	transcriptional regulator
RQCS_RS20655	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
RQCS_RS20670	COG0471	metal ion transport
RQCS_RS20670	COG0490	domain, Protein
RQCS_RS20680	COG2133	pyrroloquinoline quinone binding
RQCS_RS20695	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
RQCS_RS20705	COG1262	PFAM Formylglycine-generating sulfatase enzyme
RQCS_RS20710	COG3572	ergothioneine biosynthetic process
RQCS_RS20725	COG3976	FMN-binding domain protein
RQCS_RS20725	COG1053	succinate dehydrogenase
RQCS_RS20735	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
RQCS_RS20740	COG0193	aminoacyl-tRNA hydrolase activity
RQCS_RS20745	COG0318	PFAM AMP-dependent synthetase and ligase
RQCS_RS20750	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
RQCS_RS20795	COG2814	Major facilitator Superfamily
RQCS_RS20815	COG1120	ATPase activity
RQCS_RS20820	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RQCS_RS20825	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RQCS_RS20845	COG2207	Transcriptional regulator
RQCS_RS20865	COG0488	(ABC) transporter
RQCS_RS20870	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
RQCS_RS20895	COG2608	mercury ion transmembrane transporter activity
RQCS_RS20910	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
RQCS_RS20915	COG3583	domain protein
RQCS_RS20920	COG3583	domain protein
RQCS_RS20925	COG0765	amino acid transport
RQCS_RS20930	COG1126	abc transporter atp-binding protein
RQCS_RS20940	COG0084	hydrolase, TatD family'
RQCS_RS20965	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
RQCS_RS20970	COG2259	Doxx family
RQCS_RS20985	COG1393	Belongs to the ArsC family
RQCS_RS20990	COG2235	arginine
RQCS_RS20995	COG4044	May play a role in the intracellular transport of hydrophobic ligands
RQCS_RS21055	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RQCS_RS21065	COG1210	Utp--glucose-1-phosphate uridylyltransferase
RQCS_RS21070	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
RQCS_RS21085	COG1970	mechanosensitive ion channel activity
RQCS_RS21095	COG0521	Mo-molybdopterin cofactor biosynthetic process
RQCS_RS21095	COG0315	cyclic pyranopterin monophosphate synthase activity
RQCS_RS21100	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RQCS_RS21115	COG2860	membrane
RQCS_RS21125	COG0254	rRNA binding
RQCS_RS21135	COG0227	Belongs to the bacterial ribosomal protein bL28 family
RQCS_RS21145	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
RQCS_RS21150	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
RQCS_RS21195	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RQCS_RS21200	COG2957	Belongs to the agmatine deiminase family
RQCS_RS21210	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
RQCS_RS21255	COG1739	Uncharacterized protein family UPF0029
RQCS_RS21265	COG0045	succinate-CoA ligase (ADP-forming) activity
RQCS_RS21275	COG0739	heme binding
RQCS_RS21320	COG1131	(ABC) transporter
RQCS_RS21335	COG1252	NADH dehydrogenase
RQCS_RS21345	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RQCS_RS21350	COG2272	Belongs to the type-B carboxylesterase lipase family
RQCS_RS21355	COG2272	Belongs to the type-B carboxylesterase lipase family
RQCS_RS21365	COG1396	sequence-specific DNA binding
RQCS_RS21375	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RQCS_RS21400	COG2814	Major facilitator Superfamily
RQCS_RS21405	COG0583	DNA-binding transcription factor activity
RQCS_RS21410	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
RQCS_RS21415	COG3706	GGDEF domain
RQCS_RS21430	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
RQCS_RS21465	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RQCS_RS21485	COG1113	amino acid transport
RQCS_RS21495	COG1070	Carbohydrate kinase
RQCS_RS21510	COG1940	carbohydrate kinase activity
RQCS_RS21510	COG1846	Transcriptional regulator
RQCS_RS21515	COG0477	Major facilitator Superfamily
RQCS_RS21520	COG1024	Enoyl-CoA hydratase
RQCS_RS21545	COG1262	PFAM Formylglycine-generating sulfatase enzyme
RQCS_RS21550	COG2175	clavaminate synthase activity
RQCS_RS21560	COG3119	arylsulfatase activity
RQCS_RS21570	COG3850	Histidine kinase
RQCS_RS21570	COG0642	Histidine kinase
RQCS_RS21605	COG0477	Major facilitator Superfamily
RQCS_RS21635	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RQCS_RS21645	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RQCS_RS21655	COG3279	Response regulator of the LytR AlgR family
RQCS_RS21660	COG3275	phosphorelay sensor kinase activity
RQCS_RS21675	COG0025	NhaP-type Na H and K H
RQCS_RS21690	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
RQCS_RS21710	COG2072	flavoprotein involved in K transport
RQCS_RS21715	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RQCS_RS21730	COG2018	Roadblock/LC7 domain
RQCS_RS21765	COG0492	ferredoxin-NADP+ reductase activity
RQCS_RS21775	COG1846	Transcriptional regulator
RQCS_RS21780	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
RQCS_RS21800	COG0488	(ABC) transporter
RQCS_RS21805	COG0656	L-ascorbic acid biosynthetic process
RQCS_RS21815	COG0346	lactoylglutathione lyase activity
RQCS_RS21835	COG4152	abc transporter atp-binding protein
RQCS_RS21840	COG1668	transmembrane transport
RQCS_RS21885	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RQCS_RS21895	COG2814	Major facilitator Superfamily
RQCS_RS21910	COG0415	Belongs to the DNA photolyase family
RQCS_RS21945	COG0659	secondary active sulfate transmembrane transporter activity
RQCS_RS21950	COG0667	Aldo Keto reductase
RQCS_RS21970	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RQCS_RS21990	COG3284	Transcriptional regulator
RQCS_RS21995	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RQCS_RS22000	COG0508	dehydrogenase complex catalyzes the overall conversion of
RQCS_RS22005	COG0022	dehydrogenase e1 component
RQCS_RS22010	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
RQCS_RS22035	COG0745	RESPONSE REGULATOR receiver
RQCS_RS22040	COG2205	protein histidine kinase activity
RQCS_RS22045	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
RQCS_RS22050	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
RQCS_RS22080	COG0545	Peptidyl-prolyl cis-trans isomerase
RQCS_RS22090	COG2017	converts alpha-aldose to the beta-anomer
RQCS_RS22100	COG0259	pyridoxamine-phosphate oxidase activity
RQCS_RS22110	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
RQCS_RS22130	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RQCS_RS22155	COG2252	PERMEase
RQCS_RS22190	COG2814	Major facilitator Superfamily
RQCS_RS22200	COG1278	Cold shock
RQCS_RS22245	COG1063	alcohol dehydrogenase
RQCS_RS22250	COG1061	Type III restriction enzyme res subunit
RQCS_RS22265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RQCS_RS22275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RQCS_RS22295	COG1595	DNA-templated transcription, initiation
RQCS_RS22300	COG1289	transmembrane transporter activity
RQCS_RS22310	COG1309	transcriptional regulator
RQCS_RS22320	COG2072	flavoprotein involved in K transport
RQCS_RS22345	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS22395	COG1522	sequence-specific DNA binding
RQCS_RS22400	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
RQCS_RS22410	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
RQCS_RS22450	COG0318	PFAM AMP-dependent synthetase and ligase
RQCS_RS22455	COG1024	Enoyl-CoA hydratase
RQCS_RS22465	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS22470	COG0583	DNA-binding transcription factor activity
RQCS_RS22475	COG0477	Major facilitator Superfamily
RQCS_RS22480	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
RQCS_RS22495	COG0673	inositol 2-dehydrogenase activity
RQCS_RS22510	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
RQCS_RS22530	COG4335	DNA alkylation repair
RQCS_RS22545	COG1012	belongs to the aldehyde dehydrogenase family
RQCS_RS22550	COG0506	proline dehydrogenase activity
RQCS_RS22555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RQCS_RS22570	COG1131	(ABC) transporter
RQCS_RS22580	COG4585	Histidine kinase
RQCS_RS22585	COG2197	response regulator
RQCS_RS22595	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
RQCS_RS22605	COG1309	transcriptional regulator
RQCS_RS22635	COG0542	response to heat
RQCS_RS22645	COG2814	Major facilitator Superfamily
RQCS_RS22650	COG2084	Dehydrogenase
RQCS_RS22670	COG1574	metal-dependent hydrolase with the TIM-barrel fold
RQCS_RS22690	COG2197	response regulator
RQCS_RS22730	COG1846	Transcriptional regulator
RQCS_RS22735	COG1764	response to oxidative stress
RQCS_RS22740	COG2130	NADP-dependent
RQCS_RS22780	COG1953	Uracil, thiamine, allantoin
RQCS_RS22790	COG2814	Major facilitator Superfamily
RQCS_RS22795	COG0640	Transcriptional regulator
RQCS_RS22815	COG2072	flavoprotein involved in K transport
RQCS_RS22835	COG4266	Belongs to the allantoicase family
RQCS_RS22850	COG0564	pseudouridine synthase activity
RQCS_RS22860	COG0589	response to stress
RQCS_RS22870	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS22875	COG1309	transcriptional regulator
RQCS_RS22885	COG0477	Major facilitator Superfamily
RQCS_RS22890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RQCS_RS22895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RQCS_RS22930	COG0477	Major facilitator Superfamily
RQCS_RS22950	COG1309	transcriptional regulator
RQCS_RS22995	COG0583	DNA-binding transcription factor activity
RQCS_RS23025	COG0829	nickel cation binding
RQCS_RS23030	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
RQCS_RS23040	COG0804	urea catabolic process
RQCS_RS23045	COG0832	Belongs to the urease beta subunit family
RQCS_RS23050	COG0831	urea catabolic process
RQCS_RS23055	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
RQCS_RS23060	COG0581	inorganic phosphate transmembrane transporter activity
RQCS_RS23075	COG0456	acetyltransferase
RQCS_RS23075	COG0454	-acetyltransferase
RQCS_RS23080	COG0745	RESPONSE REGULATOR receiver
RQCS_RS23100	COG2897	thiosulfate sulfurtransferase activity
RQCS_RS23110	COG4044	May play a role in the intracellular transport of hydrophobic ligands
RQCS_RS23120	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
RQCS_RS23125	COG4988	ABC transporter
RQCS_RS23130	COG1294	oxidase, subunit
RQCS_RS23135	COG1271	oxidase subunit
RQCS_RS23165	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
RQCS_RS23205	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
RQCS_RS23210	COG2837	iron assimilation
RQCS_RS23215	COG1362	aminopeptidase activity
RQCS_RS23230	COG1960	acyl-CoA dehydrogenase activity
RQCS_RS23235	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
RQCS_RS23240	COG0135	phosphoribosylanthranilate isomerase activity
RQCS_RS23250	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS23265	COG2130	NADP-dependent
RQCS_RS23275	COG1960	acyl-CoA dehydrogenase activity
RQCS_RS23280	COG1609	Transcriptional regulator
RQCS_RS23295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RQCS_RS23300	COG0657	acetylesterase activity
RQCS_RS23315	COG2072	flavoprotein involved in K transport
RQCS_RS23350	COG4521	taurine ABC transporter
RQCS_RS23355	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RQCS_RS23385	COG2304	oxidoreductase activity
RQCS_RS23390	COG5002	protein histidine kinase activity
RQCS_RS23390	COG3447	MASE1 domain protein
RQCS_RS23390	COG5001	Diguanylate cyclase
RQCS_RS23400	COG1846	Transcriptional regulator
RQCS_RS23430	COG2072	flavoprotein involved in K transport
RQCS_RS23465	COG1983	PspC domain protein
RQCS_RS23490	COG1733	regulation of RNA biosynthetic process
RQCS_RS23495	COG0778	Nitroreductase
RQCS_RS23500	COG1174	glycine betaine transport
RQCS_RS23510	COG1174	glycine betaine transport
RQCS_RS23520	COG4106	trans-aconitate 2-methyltransferase activity
RQCS_RS23530	COG0318	PFAM AMP-dependent synthetase and ligase
RQCS_RS23540	COG1960	acyl-CoA dehydrogenase activity
RQCS_RS23545	COG1309	transcriptional regulator
RQCS_RS23605	COG1574	metal-dependent hydrolase with the TIM-barrel fold
RQCS_RS23620	COG0488	(ABC) transporter
RQCS_RS23635	COG1053	succinate dehydrogenase
RQCS_RS23645	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS23685	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
RQCS_RS23700	COG3590	peptidase
RQCS_RS23705	COG1742	UPF0060 membrane protein
RQCS_RS23710	COG3842	ATPase activity
RQCS_RS23725	COG1175	transmembrane transport
RQCS_RS23730	COG1376	ErfK ybiS ycfS ynhG family protein
RQCS_RS23745	COG3360	Dodecin
RQCS_RS23750	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RQCS_RS23765	COG1793	dna ligase
RQCS_RS23775	COG0598	Magnesium transport protein CorA
RQCS_RS23785	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS23800	COG4166	transmembrane transport
RQCS_RS23810	COG0444	Belongs to the ABC transporter superfamily
RQCS_RS23835	COG4948	Mandelate Racemase Muconate Lactonizing
RQCS_RS23855	COG0318	PFAM AMP-dependent synthetase and ligase
RQCS_RS23890	COG1408	metallophosphoesterase
RQCS_RS23900	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
RQCS_RS23910	COG0277	FAD linked oxidase domain protein
RQCS_RS23915	COG2318	DinB family
RQCS_RS23920	COG0326	Molecular chaperone. Has ATPase activity
RQCS_RS23925	COG1960	acyl-CoA dehydrogenase activity
RQCS_RS23930	COG1960	acyl-CoA dehydrogenase activity
RQCS_RS23945	COG1846	Transcriptional regulator
RQCS_RS23950	COG1673	EVE domain
RQCS_RS23955	COG1309	transcriptional regulator
RQCS_RS23970	COG0300	oxidoreductase activity
RQCS_RS23975	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
RQCS_RS23985	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
RQCS_RS23990	COG2079	MmgE PrpD family protein
RQCS_RS23995	COG1396	sequence-specific DNA binding
RQCS_RS23995	COG3800	Transcriptional regulator
RQCS_RS24010	COG2015	COG2015, Alkyl sulfatase and related hydrolases
RQCS_RS24025	COG2271	Major facilitator Superfamily
RQCS_RS24030	COG0667	Aldo Keto reductase
RQCS_RS24055	COG0129	dihydroxy-acid dehydratase activity
RQCS_RS24070	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
RQCS_RS24080	COG0477	Major facilitator Superfamily
RQCS_RS24090	COG3185	4-Hydroxyphenylpyruvate dioxygenase
RQCS_RS24100	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
RQCS_RS24115	COG0583	DNA-binding transcription factor activity
RQCS_RS24125	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS24130	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS24140	COG2030	dehydratase
RQCS_RS24145	COG0183	Belongs to the thiolase family
RQCS_RS24155	COG1960	acyl-CoA dehydrogenase activity
RQCS_RS24165	COG1960	acyl-CoA dehydrogenase activity
RQCS_RS24185	COG2011	ABC-type metal ion transport system permease component
RQCS_RS24225	COG0318	PFAM AMP-dependent synthetase and ligase
RQCS_RS24230	COG0318	PFAM AMP-dependent synthetase and ligase
RQCS_RS24240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RQCS_RS24245	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
RQCS_RS24270	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS24280	COG2030	dehydratase
RQCS_RS24285	COG0183	Belongs to the thiolase family
RQCS_RS24290	COG1960	acyl-CoA dehydrogenase activity
RQCS_RS24295	COG0183	Belongs to the thiolase family
RQCS_RS24300	COG1309	transcriptional regulator
RQCS_RS24310	COG2015	COG2015, Alkyl sulfatase and related hydrolases
RQCS_RS24335	COG0640	Transcriptional regulator
RQCS_RS24340	COG0174	glutamine synthetase
RQCS_RS24345	COG1960	acyl-CoA dehydrogenase activity
RQCS_RS24370	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS24405	COG2902	Dehydrogenase
RQCS_RS24410	COG1960	acyl-CoA dehydrogenase activity
RQCS_RS24430	COG2986	histidine ammonia-lyase
RQCS_RS24435	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
RQCS_RS24440	COG0277	FAD linked oxidase domain protein
RQCS_RS24445	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
RQCS_RS24450	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
RQCS_RS24455	COG1228	amidohydrolase
RQCS_RS24475	COG1309	transcriptional regulator
RQCS_RS24490	COG2175	clavaminate synthase activity
RQCS_RS24495	COG0789	Transcriptional regulator
RQCS_RS24505	COG0318	PFAM AMP-dependent synthetase and ligase
RQCS_RS24520	COG1309	transcriptional regulator
RQCS_RS24525	COG1309	transcriptional regulator
RQCS_RS24565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RQCS_RS24580	COG0318	PFAM AMP-dependent synthetase and ligase
RQCS_RS24585	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS24610	COG0604	alcohol dehydrogenase
RQCS_RS24635	COG0640	Transcriptional regulator
RQCS_RS24640	COG0183	Belongs to the thiolase family
RQCS_RS24650	COG2188	Transcriptional regulator
RQCS_RS24660	COG2301	Belongs to the HpcH HpaI aldolase family
RQCS_RS24670	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RQCS_RS24675	COG1960	acyl-CoA dehydrogenase activity
RQCS_RS24680	COG2271	Major facilitator Superfamily
RQCS_RS24685	COG0183	Belongs to the thiolase family
RQCS_RS24705	COG0583	DNA-binding transcription factor activity
RQCS_RS24710	COG0583	DNA-binding transcription factor activity
RQCS_RS24715	COG1024	Enoyl-CoA hydratase
RQCS_RS24720	COG1024	Enoyl-CoA hydratase
RQCS_RS24725	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RQCS_RS24730	COG0318	PFAM AMP-dependent synthetase and ligase
RQCS_RS24735	COG0583	DNA-binding transcription factor activity
RQCS_RS24740	COG0583	DNA-binding transcription factor activity
RQCS_RS24750	COG1960	acyl-CoA dehydrogenase activity
RQCS_RS24755	COG0183	Belongs to the thiolase family
RQCS_RS24760	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RQCS_RS24770	COG1960	acyl-CoA dehydrogenase activity
RQCS_RS24775	COG0318	PFAM AMP-dependent synthetase and ligase
RQCS_RS24780	COG1024	Enoyl-CoA hydratase
RQCS_RS24785	COG1012	belongs to the aldehyde dehydrogenase family
RQCS_RS24790	COG0653	protein targeting
RQCS_RS24795	COG0653	protein targeting
RQCS_RS24805	COG0028	Belongs to the TPP enzyme family
RQCS_RS24840	COG1012	belongs to the aldehyde dehydrogenase family
RQCS_RS24860	COG1846	Transcriptional regulator
RQCS_RS24870	COG1984	allophanate hydrolase subunit 2
RQCS_RS24880	COG2409	Drug exporters of the RND superfamily
RQCS_RS24890	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
RQCS_RS24895	COG1595	DNA-templated transcription, initiation
RQCS_RS24900	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
RQCS_RS24910	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS24920	COG1960	acyl-CoA dehydrogenase activity
RQCS_RS24925	COG1132	(ABC) transporter
RQCS_RS24930	COG1309	transcriptional regulator
RQCS_RS24965	COG2365	Tyrosine phosphatase family
RQCS_RS24975	COG1309	transcriptional regulator
RQCS_RS24995	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS25000	COG1960	acyl-CoA dehydrogenase activity
RQCS_RS25015	COG0277	FAD linked oxidase domain protein
RQCS_RS25020	COG4941	Belongs to the sigma-70 factor family
RQCS_RS25025	COG3795	YCII-related domain
RQCS_RS25040	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS25045	COG1556	Lactate utilization protein
RQCS_RS25050	COG1139	Iron-sulfur cluster binding protein
RQCS_RS25055	COG0247	lactate metabolic process
RQCS_RS25060	COG1802	Transcriptional regulator
RQCS_RS25085	COG1172	Belongs to the binding-protein-dependent transport system permease family
RQCS_RS25110	COG1609	Transcriptional regulator
RQCS_RS25115	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RQCS_RS25135	COG2207	Transcriptional regulator
RQCS_RS25135	COG3708	Transcriptional regulator
RQCS_RS25150	COG3485	protocatechuate 3,4-dioxygenase
RQCS_RS25155	COG3485	protocatechuate 3,4-dioxygenase
RQCS_RS25160	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
RQCS_RS25165	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RQCS_RS25170	COG1414	Transcriptional regulator
RQCS_RS25200	COG1278	Cold shock
RQCS_RS25225	COG0668	transmembrane transport
RQCS_RS25230	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
RQCS_RS25235	COG0590	tRNA wobble adenosine to inosine editing
RQCS_RS25260	COG2267	carboxylic ester hydrolase activity
RQCS_RS25270	COG1305	Transglutaminase-like
RQCS_RS25275	COG0657	acetylesterase activity
RQCS_RS25290	COG3265	gluconokinase activity
RQCS_RS25300	COG2186	Transcriptional regulator
RQCS_RS25305	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
RQCS_RS25310	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS25340	COG2030	dehydratase
RQCS_RS25350	COG2267	carboxylic ester hydrolase activity
RQCS_RS25370	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
RQCS_RS25410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RQCS_RS25435	COG3119	arylsulfatase activity
RQCS_RS25445	COG0531	amino acid
RQCS_RS25455	COG2267	carboxylic ester hydrolase activity
RQCS_RS25475	COG1725	Transcriptional regulator
RQCS_RS25485	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RQCS_RS25490	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
RQCS_RS25495	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
RQCS_RS25515	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
RQCS_RS25530	COG2132	Multicopper oxidase
RQCS_RS25555	COG1132	(ABC) transporter
RQCS_RS25570	COG2132	Multicopper oxidase
RQCS_RS25620	COG3467	pyridoxamine 5'-phosphate
RQCS_RS25655	COG1959	2 iron, 2 sulfur cluster binding
RQCS_RS25670	COG1063	alcohol dehydrogenase
RQCS_RS25690	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
RQCS_RS25740	COG2807	transmembrane transport
RQCS_RS25745	COG3145	DNA-N1-methyladenine dioxygenase activity
RQCS_RS25750	COG0640	Transcriptional regulator
RQCS_RS25775	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RQCS_RS25780	COG0477	Major facilitator Superfamily
RQCS_RS25795	COG3835	regulator
RQCS_RS25820	COG2197	response regulator
RQCS_RS25840	COG4829	muconolactone delta-isomerase
RQCS_RS25845	COG4948	Mandelate Racemase Muconate Lactonizing
RQCS_RS25850	COG3485	protocatechuate 3,4-dioxygenase
RQCS_RS25855	COG1414	Transcriptional regulator
RQCS_RS25875	COG4638	Rieske (2fe-2S)
RQCS_RS25880	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
RQCS_RS25895	COG2814	Major facilitator Superfamily
RQCS_RS25930	COG2223	nitrite transmembrane transporter activity
RQCS_RS25935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RQCS_RS25965	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS26000	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RQCS_RS26025	COG0833	amino acid
RQCS_RS26035	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
RQCS_RS26040	COG1522	sequence-specific DNA binding
RQCS_RS26070	COG0518	GMP synthase (glutamine-hydrolyzing) activity
RQCS_RS26070	COG0519	Catalyzes the synthesis of GMP from XMP
RQCS_RS26080	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
RQCS_RS26090	COG0640	Transcriptional regulator
RQCS_RS26115	COG0183	Belongs to the thiolase family
RQCS_RS26125	COG1960	acyl-CoA dehydrogenase activity
RQCS_RS26130	COG1960	acyl-CoA dehydrogenase activity
RQCS_RS26155	COG1024	Enoyl-CoA hydratase
RQCS_RS26160	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS26175	COG0318	PFAM AMP-dependent synthetase and ligase
RQCS_RS26200	COG0318	PFAM AMP-dependent synthetase and ligase
RQCS_RS26215	COG1802	Transcriptional regulator
RQCS_RS26220	COG1119	ATPase activity
RQCS_RS26240	COG3300	MHYT domain
RQCS_RS26240	COG5001	Diguanylate cyclase
RQCS_RS26245	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RQCS_RS26260	COG1802	Transcriptional regulator
RQCS_RS26335	COG3835	regulator
RQCS_RS26345	COG2814	Major facilitator Superfamily
RQCS_RS26365	COG1053	succinate dehydrogenase
RQCS_RS26375	COG0471	metal ion transport
RQCS_RS26410	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
RQCS_RS26415	COG1959	2 iron, 2 sulfur cluster binding
RQCS_RS26420	COG1017	nitric oxide dioxygenase activity
RQCS_RS26420	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RQCS_RS26435	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RQCS_RS26440	COG2151	metal-sulfur cluster biosynthetic enzyme
RQCS_RS26445	COG3396	Phenylacetate-CoA oxygenase
RQCS_RS26450	COG3460	Phenylacetate-CoA oxygenase
RQCS_RS26455	COG3396	Phenylacetate-CoA oxygenase
RQCS_RS26460	COG1024	Enoyl-CoA hydratase
RQCS_RS26465	COG1250	3-hydroxyacyl-CoA dehydrogenase
RQCS_RS26470	COG1024	Enoyl-CoA hydratase
RQCS_RS26480	COG1012	belongs to the aldehyde dehydrogenase family
RQCS_RS26480	COG2030	dehydratase
RQCS_RS26490	COG2050	protein possibly involved in aromatic compounds catabolism
RQCS_RS26490	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
RQCS_RS26495	COG3458	cephalosporin-C deacetylase activity
RQCS_RS26520	COG0596	Alpha beta hydrolase
RQCS_RS26530	COG1012	belongs to the aldehyde dehydrogenase family
RQCS_RS26540	COG1113	amino acid transport
RQCS_RS26545	COG2199	diguanylate cyclase activity
RQCS_RS26550	COG5001	Diguanylate cyclase
RQCS_RS26555	COG0477	Major facilitator Superfamily
RQCS_RS26560	COG3552	Protein containing von Willebrand factor type A (VWA) domain
RQCS_RS26575	COG0714	Associated with various cellular activities
RQCS_RS26610	COG0318	PFAM AMP-dependent synthetase and ligase
RQCS_RS26645	COG1252	NADH dehydrogenase
RQCS_RS26650	COG0583	DNA-binding transcription factor activity
RQCS_RS26660	COG0477	Major facilitator Superfamily
RQCS_RS26670	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS26685	COG0657	acetylesterase activity
RQCS_RS26700	COG2124	cytochrome p450
RQCS_RS26705	COG2130	NADP-dependent
RQCS_RS26725	COG4221	oxidoreductase activity
RQCS_RS26740	COG0318	PFAM AMP-dependent synthetase and ligase
RQCS_RS26745	COG1024	Enoyl-CoA hydratase
RQCS_RS26755	COG1072	(Pantothenic acid kinase))
RQCS_RS26780	COG1609	Transcriptional regulator
RQCS_RS26795	COG0477	Major facilitator Superfamily
RQCS_RS26810	COG2186	Transcriptional regulator
RQCS_RS26815	COG2226	methyltransferase
RQCS_RS26820	COG1607	acyl-coa hydrolase
RQCS_RS26865	COG2376	Dihydroxyacetone kinase
RQCS_RS26885	COG0183	Belongs to the thiolase family
RQCS_RS26890	COG0515	serine threonine protein kinase
RQCS_RS26910	COG4221	oxidoreductase activity
RQCS_RS26930	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
RQCS_RS26940	COG4977	sequence-specific DNA binding
RQCS_RS26940	COG1917	Cupin 2, conserved barrel domain protein
RQCS_RS26950	COG2186	Transcriptional regulator
RQCS_RS26970	COG2909	trisaccharide binding
RQCS_RS27085	COG2267	carboxylic ester hydrolase activity
RQCS_RS27100	COG1309	transcriptional regulator
RQCS_RS27105	COG1250	3-hydroxyacyl-CoA dehydrogenase
RQCS_RS27115	COG0070	glutamate synthase
RQCS_RS27115	COG0067	glutamate synthase
RQCS_RS27115	COG0069	glutamate synthase activity
RQCS_RS27120	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
RQCS_RS27130	COG1132	(ABC) transporter
RQCS_RS27135	COG1132	(ABC) transporter
RQCS_RS27145	COG0183	Belongs to the thiolase family
RQCS_RS27160	COG2375	cellular response to nickel ion
RQCS_RS27165	COG2207	Transcriptional regulator
RQCS_RS27170	COG2957	Belongs to the agmatine deiminase family
RQCS_RS27200	COG0318	PFAM AMP-dependent synthetase and ligase
RQCS_RS27210	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS27230	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
RQCS_RS27245	COG3511	phospholipase C
RQCS_RS27255	COG0657	acetylesterase activity
RQCS_RS27260	COG1733	regulation of RNA biosynthetic process
RQCS_RS27290	COG2146	nitrite reductase [NAD(P)H] activity
RQCS_RS27290	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
RQCS_RS27305	COG0596	Alpha beta hydrolase
RQCS_RS27310	COG3629	intracellular signal transduction
RQCS_RS27310	COG3903	Transcriptional regulator
RQCS_RS27315	COG2272	Belongs to the type-B carboxylesterase lipase family
RQCS_RS27330	COG0745	RESPONSE REGULATOR receiver
RQCS_RS27350	COG1597	lipid kinase activity
RQCS_RS27365	COG1309	transcriptional regulator
RQCS_RS27380	COG1309	transcriptional regulator
RQCS_RS27420	COG4941	Belongs to the sigma-70 factor family
RQCS_RS27455	COG0406	alpha-ribazole phosphatase activity
RQCS_RS27465	COG1012	belongs to the aldehyde dehydrogenase family
RQCS_RS27490	COG1120	ATPase activity
RQCS_RS27495	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RQCS_RS27500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RQCS_RS27505	COG4592	Periplasmic binding protein
RQCS_RS27535	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RQCS_RS27560	COG1058	Belongs to the CinA family
RQCS_RS27560	COG1546	Belongs to the CinA family
RQCS_RS27595	COG3973	AAA domain
RQCS_RS27605	COG3971	2-oxopent-4-enoate hydratase activity
RQCS_RS27610	COG4569	acetaldehyde dehydrogenase (acetylating) activity
RQCS_RS27615	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RQCS_RS27635	COG2318	DinB family
RQCS_RS27650	COG0789	Transcriptional regulator
RQCS_RS27695	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS27715	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS27730	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS27760	COG1960	acyl-CoA dehydrogenase activity
RQCS_RS27780	COG0477	Major facilitator Superfamily
RQCS_RS27785	COG0583	DNA-binding transcription factor activity
RQCS_RS27805	COG2226	methyltransferase
RQCS_RS27825	COG1846	Transcriptional regulator
RQCS_RS27835	COG3552	Protein containing von Willebrand factor type A (VWA) domain
RQCS_RS27840	COG2425	protein containing a von Willebrand factor type A (vWA) domain
RQCS_RS27845	COG0714	Associated with various cellular activities
RQCS_RS27860	COG0154	amidase activity
RQCS_RS27885	COG0583	DNA-binding transcription factor activity
RQCS_RS27895	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RQCS_RS27915	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RQCS_RS27935	COG1902	pentaerythritol trinitrate reductase activity
RQCS_RS27935	COG0446	pyridine nucleotide-disulphide oxidoreductase
RQCS_RS27945	COG1012	belongs to the aldehyde dehydrogenase family
RQCS_RS27950	COG0604	alcohol dehydrogenase
RQCS_RS27950	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS27950	COG3321	synthase
RQCS_RS27975	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
RQCS_RS27995	COG0492	ferredoxin-NADP+ reductase activity
RQCS_RS28020	COG0359	binds to the 23S rRNA
RQCS_RS28025	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
RQCS_RS28035	COG0360	Binds together with S18 to 16S ribosomal RNA
RQCS_RS28055	COG2319	Wd-40 repeat
RQCS_RS28055	COG4249	Peptidase C14 caspase catalytic subunit p20
RQCS_RS28070	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RQCS_RS28100	COG1260	myo-inositol-1-phosphate synthase
RQCS_RS28115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RQCS_RS28130	COG0330	HflC and HflK could
RQCS_RS28140	COG1414	Transcriptional regulator
RQCS_RS28150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RQCS_RS28155	COG1116	anion transmembrane transporter activity
RQCS_RS28165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RQCS_RS28170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RQCS_RS28180	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RQCS_RS28190	COG0251	oxidation-reduction process
RQCS_RS28195	COG2267	carboxylic ester hydrolase activity
RQCS_RS28205	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RQCS_RS28210	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RQCS_RS28215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RQCS_RS28220	COG1116	anion transmembrane transporter activity
RQCS_RS28220	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RQCS_RS28235	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
RQCS_RS28265	COG2233	PERMEase
RQCS_RS28285	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
RQCS_RS28290	COG2508	Transcriptional regulator
RQCS_RS28305	COG2233	PERMEase
RQCS_RS28315	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
RQCS_RS28315	COG3608	succinylglutamate desuccinylase aspartoacylase
RQCS_RS28345	COG0154	amidase activity
RQCS_RS28365	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RQCS_RS28390	COG3842	ATPase activity
RQCS_RS28410	COG0740	serine-type endopeptidase activity
RQCS_RS28415	COG0740	serine-type endopeptidase activity
RQCS_RS28425	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RQCS_RS28430	COG1960	acyl-CoA dehydrogenase activity
RQCS_RS28435	COG0477	Major facilitator Superfamily
RQCS_RS28440	COG0583	DNA-binding transcription factor activity
RQCS_RS28445	COG1960	acyl-CoA dehydrogenase activity
RQCS_RS28455	COG1309	transcriptional regulator
RQCS_RS28500	COG0765	amino acid transport
RQCS_RS28505	COG1126	abc transporter atp-binding protein
RQCS_RS28510	COG4941	Belongs to the sigma-70 factor family
RQCS_RS28515	COG3795	YCII-related domain
RQCS_RS28520	COG2197	response regulator
RQCS_RS28535	COG1131	(ABC) transporter
RQCS_RS28560	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
RQCS_RS28580	COG1796	DNA polymerase
RQCS_RS28580	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
RQCS_RS28600	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RQCS_RS28605	COG1121	(ABC) transporter
RQCS_RS28635	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RQCS_RS28640	COG0508	dehydrogenase complex catalyzes the overall conversion of
RQCS_RS28655	COG1522	sequence-specific DNA binding
RQCS_RS28660	COG3220	belongs to the UPF0276 family
RQCS_RS28675	COG2837	iron assimilation
RQCS_RS28685	COG2267	carboxylic ester hydrolase activity
RQCS_RS28690	COG3631	Ketosteroid isomerase-related protein
RQCS_RS28710	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
RQCS_RS28715	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS28735	COG0477	Major facilitator Superfamily
RQCS_RS28740	COG0495	leucyl-tRNA aminoacylation
RQCS_RS28755	COG2186	Transcriptional regulator
RQCS_RS28760	COG2814	Major facilitator Superfamily
RQCS_RS28775	COG1678	Uncharacterized ACR, COG1678
RQCS_RS28795	COG1960	acyl-CoA dehydrogenase activity
RQCS_RS28805	COG0617	tRNA 3'-terminal CCA addition
RQCS_RS28825	COG1595	DNA-templated transcription, initiation
RQCS_RS28855	COG0860	N-Acetylmuramoyl-L-alanine amidase
RQCS_RS28855	COG3409	Peptidoglycan-binding domain 1 protein
RQCS_RS28870	COG1192	Involved in chromosome partitioning
RQCS_RS28875	COG0357	Ribosomal RNA small subunit methyltransferase G
RQCS_RS28900	COG0706	membrane insertase activity
RQCS_RS28905	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
RQCS_RS28910	COG0594	ribonuclease P activity
RQCS_RS28915	COG0230	Belongs to the bacterial ribosomal protein bL34 family
RQCS_RS29000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RQCS_RS29005	COG2271	Major facilitator Superfamily
RQCS_RS29010	COG1902	pentaerythritol trinitrate reductase activity
RQCS_RS29010	COG0446	pyridine nucleotide-disulphide oxidoreductase
RQCS_RS29055	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
RQCS_RS29065	COG0701	Predicted permease
RQCS_RS29070	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
RQCS_RS29080	COG1126	abc transporter atp-binding protein
RQCS_RS29085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RQCS_RS29090	COG0765	amino acid transport
RQCS_RS29095	COG0765	amino acid transport
RQCS_RS29100	COG1024	Enoyl-CoA hydratase
RQCS_RS29105	COG0045	succinate-CoA ligase (ADP-forming) activity
RQCS_RS29105	COG1042	CoA-binding domain protein
RQCS_RS29105	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RQCS_RS29110	COG1024	Enoyl-CoA hydratase
RQCS_RS29130	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS29185	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
RQCS_RS29205	COG0114	fumarate hydratase activity
RQCS_RS29210	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
RQCS_RS29320	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RQCS_RS29325	COG1609	Transcriptional regulator
RQCS_RS29330	COG2271	Major facilitator Superfamily
RQCS_RS29355	COG1733	regulation of RNA biosynthetic process
RQCS_RS29410	COG0179	Fumarylacetoacetate (FAA) hydrolase
RQCS_RS29415	COG0318	PFAM AMP-dependent synthetase and ligase
RQCS_RS29435	COG0183	Belongs to the thiolase family
RQCS_RS29440	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS29480	COG3485	protocatechuate 3,4-dioxygenase
RQCS_RS29495	COG2267	carboxylic ester hydrolase activity
RQCS_RS29555	COG3384	dioxygenase
RQCS_RS29585	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS29600	COG1063	alcohol dehydrogenase
RQCS_RS29615	COG4948	Mandelate Racemase Muconate Lactonizing
RQCS_RS29620	COG3958	Transketolase
RQCS_RS29625	COG3959	Transketolase, thiamine diphosphate binding domain
RQCS_RS29635	COG4221	oxidoreductase activity
RQCS_RS29640	COG0477	Major facilitator Superfamily
RQCS_RS29650	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
RQCS_RS29725	COG0174	glutamine synthetase
RQCS_RS29730	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
RQCS_RS29735	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
RQCS_RS29745	COG1012	belongs to the aldehyde dehydrogenase family
RQCS_RS29790	COG0789	Transcriptional regulator
RQCS_RS29820	COG0693	protein deglycase activity
RQCS_RS29850	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
RQCS_RS29865	COG0745	RESPONSE REGULATOR receiver
RQCS_RS29870	COG5002	protein histidine kinase activity
RQCS_RS29880	COG2890	protein-(glutamine-N5) methyltransferase activity
RQCS_RS29885	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RQCS_RS29965	COG2217	Heavy metal translocating P-type atpase
RQCS_RS29980	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
RQCS_RS29985	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RQCS_RS30060	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
RQCS_RS30060	COG0574	Belongs to the PEP-utilizing enzyme family
RQCS_RS30065	COG0517	IMP dehydrogenase activity
RQCS_RS30065	COG0617	tRNA 3'-terminal CCA addition
RQCS_RS30065	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
RQCS_RS30165	COG1595	DNA-templated transcription, initiation
RQCS_RS30345	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
RQCS_RS30370	COG3835	regulator
RQCS_RS30375	COG0402	S-adenosylhomocysteine deaminase activity
RQCS_RS30395	COG2233	PERMEase
RQCS_RS30485	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS30490	COG0583	DNA-binding transcription factor activity
RQCS_RS30500	COG0463	Glycosyl transferase, family 2
RQCS_RS30505	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
RQCS_RS30520	COG3835	regulator
RQCS_RS30525	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
RQCS_RS30535	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RQCS_RS30575	COG0583	DNA-binding transcription factor activity
RQCS_RS30580	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS30590	COG1028	Short-chain dehydrogenase reductase Sdr
RQCS_RS30600	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
RQCS_RS30605	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
RQCS_RS30610	COG0318	PFAM AMP-dependent synthetase and ligase
RQCS_RS30615	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RQCS_RS30645	COG1570	exodeoxyribonuclease VII activity
RQCS_RS30680	COG0596	Alpha beta hydrolase
RQCS_RS30695	COG1388	LysM domain
RQCS_RS30695	COG0791	NLP P60 protein
RQCS_RS30865	COG3285	dna ligase
RQCS_RS30865	COG1793	dna ligase
RQCS_RS30885	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RQCS_RS30890	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
RQCS_RS30895	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
RQCS_RS30915	COG3135	benzoate transporter
RQCS_RS30920	COG3415	Transposase
RQCS_RS30920	COG2801	Transposase and inactivated derivatives
RQCS_RS30925	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RQCS_RS30945	COG0512	Glutamine amidotransferase of anthranilate synthase
RQCS_RS30945	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
RQCS_RS30950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RQCS_RS30965	COG0154	amidase activity
RQCS_RS30970	COG2197	response regulator
RQCS_RS30975	COG0477	Major facilitator Superfamily
RQCS_RS31030	COG0583	DNA-binding transcription factor activity