locus-tag	class	description
A0W34_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
A0W34_RS00010	COG0592	DNA-directed DNA polymerase activity
A0W34_RS00015	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
A0W34_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
A0W34_RS00025	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
A0W34_RS00050	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A0W34_RS00095	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A0W34_RS00100	COG0457	Tetratricopeptide repeat
A0W34_RS00100	COG0705	Rhomboid family
A0W34_RS00120	COG0277	FAD linked oxidase domain protein
A0W34_RS00140	COG3879	Bacterial protein of unknown function (DUF881)
A0W34_RS00150	COG2815	serine threonine protein kinase
A0W34_RS00150	COG0515	serine threonine protein kinase
A0W34_RS00155	COG0515	serine threonine protein kinase
A0W34_RS00160	COG0768	penicillin binding
A0W34_RS00175	COG1716	ATPase activity
A0W34_RS00180	COG1716	ATPase activity
A0W34_RS00210	COG2184	nucleotidyltransferase activity
A0W34_RS00215	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
A0W34_RS00240	COG0693	protein deglycase activity
A0W34_RS00300	COG0789	Transcriptional regulator
A0W34_RS00345	COG2015	COG2015, Alkyl sulfatase and related hydrolases
A0W34_RS00370	COG0069	glutamate synthase activity
A0W34_RS00370	COG0070	glutamate synthase
A0W34_RS00370	COG0067	glutamate synthase
A0W34_RS00380	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
A0W34_RS00405	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
A0W34_RS00425	COG0025	NhaP-type Na H and K H
A0W34_RS00435	COG0601	transmembrane transport
A0W34_RS00440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A0W34_RS00445	COG0444	Belongs to the ABC transporter superfamily
A0W34_RS00460	COG2199	diguanylate cyclase activity
A0W34_RS00470	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
A0W34_RS00470	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
A0W34_RS00475	COG2501	S4 domain
A0W34_RS00480	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
A0W34_RS00500	COG2365	Tyrosine phosphatase family
A0W34_RS00535	COG0318	PFAM AMP-dependent synthetase and ligase
A0W34_RS00550	COG4716	Myosin-crossreactive antigen
A0W34_RS00565	COG2271	Major facilitator Superfamily
A0W34_RS00580	COG0506	proline dehydrogenase activity
A0W34_RS00605	COG2197	response regulator
A0W34_RS00620	COG1136	(ABC) transporter
A0W34_RS00620	COG0577	efflux transmembrane transporter activity
A0W34_RS00670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A0W34_RS00675	COG1120	ATPase activity
A0W34_RS00710	COG2318	DinB family
A0W34_RS00715	COG1288	antiporter activity
A0W34_RS00740	COG3119	arylsulfatase activity
A0W34_RS00755	COG4424	Sulfotransferase
A0W34_RS00790	COG5001	Diguanylate cyclase
A0W34_RS00810	COG1403	HNH endonuclease
A0W34_RS00825	COG0183	Belongs to the thiolase family
A0W34_RS00840	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS00845	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS00850	COG0154	amidase activity
A0W34_RS00875	COG0154	amidase activity
A0W34_RS00885	COG2271	Major facilitator Superfamily
A0W34_RS00895	COG2119	membrane
A0W34_RS00915	COG0628	permease
A0W34_RS00925	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A0W34_RS00935	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A0W34_RS00945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A0W34_RS00975	COG1528	Iron-storage protein
A0W34_RS01010	COG1528	Iron-storage protein
A0W34_RS01020	COG1316	TRANSCRIPTIONal
A0W34_RS01110	COG0204	Acyl-transferase
A0W34_RS01120	COG0561	phosphatase activity
A0W34_RS01130	COG2385	sporulation resulting in formation of a cellular spore
A0W34_RS01140	COG1113	amino acid transport
A0W34_RS01145	COG0183	Belongs to the thiolase family
A0W34_RS01150	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS01155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A0W34_RS01165	COG1216	Glycosyl transferase, family 2
A0W34_RS01175	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
A0W34_RS01180	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
A0W34_RS01185	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
A0W34_RS01190	COG5479	isomerase activity
A0W34_RS01190	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
A0W34_RS01200	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
A0W34_RS01210	COG0318	PFAM AMP-dependent synthetase and ligase
A0W34_RS01215	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
A0W34_RS01215	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A0W34_RS01215	COG3321	synthase
A0W34_RS01220	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A0W34_RS01280	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS01285	COG0277	FAD linked oxidase domain protein
A0W34_RS01310	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A0W34_RS01315	COG1215	transferase activity, transferring glycosyl groups
A0W34_RS01325	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
A0W34_RS01330	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
A0W34_RS01335	COG1088	dTDP-glucose 4,6-dehydratase activity
A0W34_RS01345	COG0463	Glycosyl transferase, family 2
A0W34_RS01360	COG1216	Glycosyl transferase, family 2
A0W34_RS01370	COG1162	GTPase activity
A0W34_RS01375	COG1216	Glycosyl transferase, family 2
A0W34_RS01480	COG0831	urea catabolic process
A0W34_RS01490	COG0804	urea catabolic process
A0W34_RS01495	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
A0W34_RS01505	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
A0W34_RS01515	COG4413	Urea transporter
A0W34_RS01520	COG3265	gluconokinase activity
A0W34_RS01525	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS01530	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A0W34_RS01540	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
A0W34_RS01545	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
A0W34_RS01555	COG0477	Major facilitator Superfamily
A0W34_RS01560	COG4221	oxidoreductase activity
A0W34_RS01565	COG1063	alcohol dehydrogenase
A0W34_RS01570	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
A0W34_RS01575	COG0436	Aminotransferase
A0W34_RS01590	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
A0W34_RS01600	COG0737	Belongs to the 5'-nucleotidase family
A0W34_RS01605	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A0W34_RS01625	COG4977	sequence-specific DNA binding
A0W34_RS01635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A0W34_RS01640	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A0W34_RS01645	COG1120	ATPase activity
A0W34_RS01685	COG0270	DNA (cytosine-5-)-methyltransferase activity
A0W34_RS01695	COG0287	Prephenate dehydrogenase
A0W34_RS01705	COG0590	tRNA wobble adenosine to inosine editing
A0W34_RS01735	COG2149	membrane
A0W34_RS01755	COG3706	GGDEF domain
A0W34_RS01765	COG2409	Drug exporters of the RND superfamily
A0W34_RS01785	COG2814	Major facilitator Superfamily
A0W34_RS01815	COG3384	dioxygenase
A0W34_RS01820	COG0508	dehydrogenase complex catalyzes the overall conversion of
A0W34_RS01820	COG0596	Alpha beta hydrolase
A0W34_RS01825	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A0W34_RS01835	COG1116	anion transmembrane transporter activity
A0W34_RS01850	COG0492	ferredoxin-NADP+ reductase activity
A0W34_RS01860	COG0596	Alpha beta hydrolase
A0W34_RS01860	COG0508	dehydrogenase complex catalyzes the overall conversion of
A0W34_RS01865	COG1414	Transcriptional regulator
A0W34_RS01880	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A0W34_RS01890	COG1024	Enoyl-CoA hydratase
A0W34_RS01895	COG0343	queuine tRNA-ribosyltransferase activity
A0W34_RS01915	COG3300	MHYT domain
A0W34_RS01915	COG5001	Diguanylate cyclase
A0W34_RS01920	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A0W34_RS01925	COG3226	Transcriptional regulator
A0W34_RS01955	COG0745	RESPONSE REGULATOR receiver
A0W34_RS01965	COG1357	PFAM Pentapeptide repeats (8 copies)
A0W34_RS01990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A0W34_RS02005	COG0583	DNA-binding transcription factor activity
A0W34_RS02010	COG2855	membrane
A0W34_RS02025	COG2175	clavaminate synthase activity
A0W34_RS02030	COG3246	L-lysine catabolic process to acetate
A0W34_RS02035	COG2814	Major facilitator Superfamily
A0W34_RS02045	COG0318	PFAM AMP-dependent synthetase and ligase
A0W34_RS02075	COG2132	Multicopper oxidase
A0W34_RS02080	COG0183	Belongs to the thiolase family
A0W34_RS02095	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A0W34_RS02125	COG0860	N-Acetylmuramoyl-L-alanine amidase
A0W34_RS02130	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
A0W34_RS02135	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
A0W34_RS02140	COG1309	transcriptional regulator
A0W34_RS02145	COG2814	Major facilitator Superfamily
A0W34_RS02150	COG1309	transcriptional regulator
A0W34_RS02170	COG0183	Belongs to the thiolase family
A0W34_RS02185	COG0183	Belongs to the thiolase family
A0W34_RS02190	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS02195	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS02200	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS02215	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
A0W34_RS02220	COG0697	spore germination
A0W34_RS02225	COG0583	DNA-binding transcription factor activity
A0W34_RS02235	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A0W34_RS02285	COG2132	Multicopper oxidase
A0W34_RS02290	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A0W34_RS02295	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A0W34_RS02320	COG4566	intracellular signal transduction
A0W34_RS02355	COG0546	phosphoglycolate phosphatase activity
A0W34_RS02360	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A0W34_RS02365	COG2205	protein histidine kinase activity
A0W34_RS02405	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A0W34_RS02430	COG1408	metallophosphoesterase
A0W34_RS02465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A0W34_RS02485	COG4101	3-hydroxyanthranilate 3,4-dioxygenase activity
A0W34_RS02495	COG0477	Major facilitator Superfamily
A0W34_RS02500	COG0583	DNA-binding transcription factor activity
A0W34_RS02510	COG1309	transcriptional regulator
A0W34_RS02540	COG0494	nUDIX hydrolase
A0W34_RS02550	COG0596	Alpha beta hydrolase
A0W34_RS02560	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
A0W34_RS02565	COG0477	Major facilitator Superfamily
A0W34_RS02600	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A0W34_RS02610	COG0601	transmembrane transport
A0W34_RS02615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A0W34_RS02620	COG4172	Belongs to the ABC transporter superfamily
A0W34_RS02670	COG1205	dead DEAH box helicase
A0W34_RS02670	COG1111	helicase
A0W34_RS02675	COG1278	Cold shock
A0W34_RS02685	COG1754	DNA topoisomerase type I activity
A0W34_RS02685	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A0W34_RS02690	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
A0W34_RS02700	COG1714	RDD family
A0W34_RS02735	COG3836	Belongs to the HpcH HpaI aldolase family
A0W34_RS02740	COG0667	Aldo Keto reductase
A0W34_RS02745	COG4608	Belongs to the ABC transporter superfamily
A0W34_RS02750	COG0444	Belongs to the ABC transporter superfamily
A0W34_RS02755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A0W34_RS02760	COG0601	transmembrane transport
A0W34_RS02765	COG0747	negative chemotaxis
A0W34_RS02775	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
A0W34_RS02780	COG1349	DNA-binding transcription factor activity
A0W34_RS02800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A0W34_RS02805	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A0W34_RS02825	COG5001	Diguanylate cyclase
A0W34_RS02825	COG3300	MHYT domain
A0W34_RS02830	COG1802	Transcriptional regulator
A0W34_RS02840	COG2268	Band 7 protein
A0W34_RS02875	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS02950	COG0477	Major facilitator Superfamily
A0W34_RS02990	COG1937	Protein conserved in bacteria
A0W34_RS03010	COG2226	methyltransferase
A0W34_RS03020	COG1396	sequence-specific DNA binding
A0W34_RS03025	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A0W34_RS03055	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A0W34_RS03060	COG0442	prolyl-tRNA aminoacylation
A0W34_RS03070	COG1309	transcriptional regulator
A0W34_RS03075	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
A0W34_RS03080	COG1285	pathogenesis
A0W34_RS03125	COG1358	cellular component organization or biogenesis
A0W34_RS03140	COG2755	lipolytic protein G-D-S-L family
A0W34_RS03205	COG0561	phosphatase activity
A0W34_RS03265	COG1309	transcriptional regulator
A0W34_RS03285	COG1316	TRANSCRIPTIONal
A0W34_RS03305	COG2027	D-alanyl-D-alanine carboxypeptidase
A0W34_RS03315	COG0037	tRNA processing
A0W34_RS03340	COG0318	PFAM AMP-dependent synthetase and ligase
A0W34_RS03350	COG2186	Transcriptional regulator
A0W34_RS03355	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A0W34_RS03360	COG0302	gtp cyclohydrolase
A0W34_RS03395	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
A0W34_RS03400	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
A0W34_RS03405	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
A0W34_RS03435	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
A0W34_RS03470	COG1024	Enoyl-CoA hydratase
A0W34_RS03480	COG1309	transcriptional regulator
A0W34_RS03500	COG4585	Histidine kinase
A0W34_RS03505	COG2197	response regulator
A0W34_RS03575	COG1194	a g-specific adenine glycosylase
A0W34_RS03615	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A0W34_RS03630	COG0288	reversible hydration of carbon dioxide
A0W34_RS03640	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
A0W34_RS03650	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
A0W34_RS03660	COG1329	Transcriptional regulator
A0W34_RS03665	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
A0W34_RS03670	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
A0W34_RS03675	COG0215	cysteine-tRNA ligase activity
A0W34_RS03680	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A0W34_RS03685	COG1132	(ABC) transporter
A0W34_RS03690	COG1132	(ABC) transporter
A0W34_RS03700	COG2207	Transcriptional regulator
A0W34_RS03720	COG1984	allophanate hydrolase subunit 2
A0W34_RS03725	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
A0W34_RS03730	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
A0W34_RS03735	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A0W34_RS03740	COG1121	(ABC) transporter
A0W34_RS03745	COG0803	Belongs to the bacterial solute-binding protein 9 family
A0W34_RS03750	COG1609	Transcriptional regulator
A0W34_RS03760	COG1309	transcriptional regulator
A0W34_RS03765	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS03770	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS03775	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS03790	COG0183	Belongs to the thiolase family
A0W34_RS03800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A0W34_RS03850	COG2890	protein-(glutamine-N5) methyltransferase activity
A0W34_RS03865	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
A0W34_RS03875	COG1136	(ABC) transporter
A0W34_RS03890	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
A0W34_RS03910	COG2030	dehydratase
A0W34_RS03915	COG1053	succinate dehydrogenase
A0W34_RS03925	COG3971	2-oxopent-4-enoate hydratase activity
A0W34_RS03930	COG4569	acetaldehyde dehydrogenase (acetylating) activity
A0W34_RS03935	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A0W34_RS03940	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS03960	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A0W34_RS04000	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS04005	COG2267	carboxylic ester hydrolase activity
A0W34_RS04010	COG0346	lactoylglutathione lyase activity
A0W34_RS04015	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A0W34_RS04030	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
A0W34_RS04040	COG2814	Major facilitator Superfamily
A0W34_RS04050	COG4689	acetoacetate decarboxylase
A0W34_RS04055	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS04060	COG2124	cytochrome p450
A0W34_RS04100	COG1116	anion transmembrane transporter activity
A0W34_RS04110	COG1074	ATP-dependent DNA helicase activity
A0W34_RS04140	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A0W34_RS04160	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
A0W34_RS04185	COG0656	L-ascorbic acid biosynthetic process
A0W34_RS04190	COG0686	Belongs to the AlaDH PNT family
A0W34_RS04210	COG0346	lactoylglutathione lyase activity
A0W34_RS04220	COG0561	phosphatase activity
A0W34_RS04240	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS04245	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS04250	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS04255	COG1024	Enoyl-CoA hydratase
A0W34_RS04260	COG0318	PFAM AMP-dependent synthetase and ligase
A0W34_RS04265	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS04270	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS04275	COG1309	transcriptional regulator
A0W34_RS04280	COG0183	Belongs to the thiolase family
A0W34_RS04320	COG0494	nUDIX hydrolase
A0W34_RS04370	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A0W34_RS04385	COG3214	Protein conserved in bacteria
A0W34_RS04400	COG1414	Transcriptional regulator
A0W34_RS04420	COG1024	Enoyl-CoA hydratase
A0W34_RS04425	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS04445	COG0183	Belongs to the thiolase family
A0W34_RS04450	COG2124	cytochrome p450
A0W34_RS04470	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
A0W34_RS04475	COG0183	Belongs to the thiolase family
A0W34_RS04485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A0W34_RS04505	COG2070	2-Nitropropane dioxygenase
A0W34_RS04510	COG2186	Transcriptional regulator
A0W34_RS04515	COG4608	Belongs to the ABC transporter superfamily
A0W34_RS04520	COG0444	Belongs to the ABC transporter superfamily
A0W34_RS04525	COG0601	transmembrane transport
A0W34_RS04530	COG0747	negative chemotaxis
A0W34_RS04540	COG0673	inositol 2-dehydrogenase activity
A0W34_RS04545	COG0673	inositol 2-dehydrogenase activity
A0W34_RS04550	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A0W34_RS04555	COG1940	carbohydrate kinase activity
A0W34_RS04570	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
A0W34_RS04580	COG0318	PFAM AMP-dependent synthetase and ligase
A0W34_RS04585	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS04590	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS04610	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A0W34_RS04635	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
A0W34_RS04655	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
A0W34_RS04660	COG1132	(ABC) transporter
A0W34_RS04665	COG1132	(ABC) transporter
A0W34_RS04680	COG1937	Protein conserved in bacteria
A0W34_RS04690	COG2409	Drug exporters of the RND superfamily
A0W34_RS04735	COG2076	Multidrug Resistance protein
A0W34_RS04750	COG0745	RESPONSE REGULATOR receiver
A0W34_RS04755	COG2205	protein histidine kinase activity
A0W34_RS04775	COG2271	Major facilitator Superfamily
A0W34_RS04780	COG3483	tryptophan 2,3-dioxygenase activity
A0W34_RS04795	COG4948	Mandelate Racemase Muconate Lactonizing
A0W34_RS04815	COG0537	adenosine 5'-monophosphoramidase activity
A0W34_RS04825	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
A0W34_RS04840	COG0444	Belongs to the ABC transporter superfamily
A0W34_RS04845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A0W34_RS04850	COG0601	transmembrane transport
A0W34_RS04880	COG0671	phosphoesterase, PA-phosphatase related
A0W34_RS04885	COG0745	RESPONSE REGULATOR receiver
A0W34_RS04890	COG2205	protein histidine kinase activity
A0W34_RS04915	COG0436	Aminotransferase
A0W34_RS04925	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A0W34_RS04940	COG2382	esterase
A0W34_RS04945	COG4592	Periplasmic binding protein
A0W34_RS04950	COG4585	Histidine kinase
A0W34_RS04955	COG2197	response regulator
A0W34_RS04960	COG2365	Tyrosine phosphatase family
A0W34_RS04970	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
A0W34_RS04980	COG4565	transcriptional regulatory protein
A0W34_RS04985	COG3290	protein histidine kinase activity
A0W34_RS04990	COG1301	dicarboxylic acid transport
A0W34_RS05010	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A0W34_RS05015	COG0386	Belongs to the glutathione peroxidase family
A0W34_RS05035	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A0W34_RS05040	COG0047	phosphoribosylformylglycinamidine synthase activity
A0W34_RS05050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A0W34_RS05070	COG2205	protein histidine kinase activity
A0W34_RS05075	COG0745	RESPONSE REGULATOR receiver
A0W34_RS05085	COG2217	Heavy metal translocating P-type atpase
A0W34_RS05100	COG0488	(ABC) transporter
A0W34_RS05125	COG3104	oligopeptide transport
A0W34_RS05140	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A0W34_RS05165	COG4585	Histidine kinase
A0W34_RS05170	COG2197	response regulator
A0W34_RS05190	COG1309	transcriptional regulator
A0W34_RS05200	COG2409	Drug exporters of the RND superfamily
A0W34_RS05210	COG0220	tRNA (guanine-N7-)-methyltransferase activity
A0W34_RS05230	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
A0W34_RS05240	COG1045	serine acetyltransferase
A0W34_RS05245	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
A0W34_RS05265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A0W34_RS05270	COG1120	ATPase activity
A0W34_RS05300	COG1940	carbohydrate kinase activity
A0W34_RS05305	COG0500	methyltransferase
A0W34_RS05340	COG4981	capsule polysaccharide biosynthetic process
A0W34_RS05360	COG1472	Belongs to the glycosyl hydrolase 3 family
A0W34_RS05365	COG1309	transcriptional regulator
A0W34_RS05370	COG2030	dehydratase
A0W34_RS05375	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS05380	COG0183	Belongs to the thiolase family
A0W34_RS05400	COG1476	TRANSCRIPTIONal
A0W34_RS05430	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS05445	COG0577	efflux transmembrane transporter activity
A0W34_RS05445	COG1136	(ABC) transporter
A0W34_RS05450	COG4585	Histidine kinase
A0W34_RS05455	COG2197	response regulator
A0W34_RS05480	COG2267	carboxylic ester hydrolase activity
A0W34_RS05510	COG2015	COG2015, Alkyl sulfatase and related hydrolases
A0W34_RS05525	COG0009	L-threonylcarbamoyladenylate synthase
A0W34_RS05530	COG0789	Transcriptional regulator
A0W34_RS05535	COG0659	secondary active sulfate transmembrane transporter activity
A0W34_RS05600	COG2837	iron assimilation
A0W34_RS05635	COG0501	Belongs to the peptidase M48B family
A0W34_RS05650	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
A0W34_RS05660	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
A0W34_RS05690	COG3707	response regulator
A0W34_RS05695	COG0596	Alpha beta hydrolase
A0W34_RS05735	COG0738	Major facilitator superfamily
A0W34_RS05755	COG0318	PFAM AMP-dependent synthetase and ligase
A0W34_RS05765	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A0W34_RS05775	COG1120	ATPase activity
A0W34_RS05780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A0W34_RS05785	COG2226	methyltransferase
A0W34_RS05800	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS05820	COG0628	permease
A0W34_RS05840	COG1470	cell adhesion involved in biofilm formation
A0W34_RS05840	COG0366	Alpha amylase catalytic
A0W34_RS05860	COG0183	Belongs to the thiolase family
A0W34_RS05890	COG2015	COG2015, Alkyl sulfatase and related hydrolases
A0W34_RS05900	COG0477	Major facilitator Superfamily
A0W34_RS05905	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
A0W34_RS05910	COG1737	Transcriptional regulator
A0W34_RS05915	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
A0W34_RS05930	COG0515	serine threonine protein kinase
A0W34_RS05930	COG2815	serine threonine protein kinase
A0W34_RS05945	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
A0W34_RS05965	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A0W34_RS06005	COG2814	Major facilitator Superfamily
A0W34_RS06035	COG1053	succinate dehydrogenase
A0W34_RS06040	COG0739	heme binding
A0W34_RS06060	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A0W34_RS06115	COG1131	(ABC) transporter
A0W34_RS06120	COG2188	Transcriptional regulator
A0W34_RS06140	COG0717	Belongs to the dCTP deaminase family
A0W34_RS06210	COG2890	protein-(glutamine-N5) methyltransferase activity
A0W34_RS06225	COG1278	Cold shock
A0W34_RS06275	COG0783	Belongs to the Dps family
A0W34_RS06280	COG0789	Transcriptional regulator
A0W34_RS06320	COG1595	DNA-templated transcription, initiation
A0W34_RS06325	COG1302	Protein conserved in bacteria
A0W34_RS06390	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A0W34_RS06400	COG1215	transferase activity, transferring glycosyl groups
A0W34_RS06440	COG2244	polysaccharide biosynthetic process
A0W34_RS06445	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
A0W34_RS06455	COG0489	protein tyrosine kinase activity
A0W34_RS06490	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
A0W34_RS06495	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
A0W34_RS06500	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A0W34_RS06505	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
A0W34_RS06510	COG0489	protein tyrosine kinase activity
A0W34_RS06515	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A0W34_RS06520	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
A0W34_RS06525	COG0443	Heat shock 70 kDa protein
A0W34_RS06590	COG1506	peptidase
A0W34_RS06590	COG4946	Tricorn protease homolog
A0W34_RS06590	COG0823	Involved in the tonB-independent uptake of proteins
A0W34_RS06610	COG2181	nitrate reductase activity
A0W34_RS06610	COG0247	lactate metabolic process
A0W34_RS06660	COG0477	Major facilitator Superfamily
A0W34_RS06665	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
A0W34_RS06680	COG0443	Heat shock 70 kDa protein
A0W34_RS06685	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
A0W34_RS06690	COG0484	heat shock protein binding
A0W34_RS06695	COG0789	Transcriptional regulator
A0W34_RS06740	COG2072	flavoprotein involved in K transport
A0W34_RS06765	COG3976	FMN-binding domain protein
A0W34_RS06765	COG1053	succinate dehydrogenase
A0W34_RS06795	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
A0W34_RS06815	COG3631	Ketosteroid isomerase-related protein
A0W34_RS06820	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A0W34_RS06830	COG1414	Transcriptional regulator
A0W34_RS06855	COG0318	PFAM AMP-dependent synthetase and ligase
A0W34_RS06865	COG3290	protein histidine kinase activity
A0W34_RS06875	COG2851	Citrate transporter
A0W34_RS06900	COG0542	response to heat
A0W34_RS06925	COG2814	Major facilitator Superfamily
A0W34_RS06935	COG1309	transcriptional regulator
A0W34_RS06955	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS06975	COG0596	Alpha beta hydrolase
A0W34_RS06985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A0W34_RS06990	COG0523	cobalamin synthesis protein
A0W34_RS06995	COG0586	Pfam SNARE associated Golgi protein
A0W34_RS07020	COG4129	membrane
A0W34_RS07040	COG2354	Protein conserved in bacteria
A0W34_RS07045	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A0W34_RS07050	COG0183	Belongs to the thiolase family
A0W34_RS07075	COG1994	Peptidase M50
A0W34_RS07085	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
A0W34_RS07100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A0W34_RS07110	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A0W34_RS07130	COG3706	GGDEF domain
A0W34_RS07135	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
A0W34_RS07160	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A0W34_RS07185	COG0681	Belongs to the peptidase S26 family
A0W34_RS07215	COG1126	abc transporter atp-binding protein
A0W34_RS07220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A0W34_RS07235	COG0747	negative chemotaxis
A0W34_RS07245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A0W34_RS07250	COG4172	Belongs to the ABC transporter superfamily
A0W34_RS07255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A0W34_RS07270	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A0W34_RS07275	COG0037	tRNA processing
A0W34_RS07275	COG0590	tRNA wobble adenosine to inosine editing
A0W34_RS07295	COG2149	membrane
A0W34_RS07300	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A0W34_RS07310	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
A0W34_RS07320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A0W34_RS07335	COG0352	thiamine-phosphate diphosphorylase activity
A0W34_RS07340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A0W34_RS07340	COG2022	thiamine diphosphate biosynthetic process
A0W34_RS07350	COG2022	thiamine diphosphate biosynthetic process
A0W34_RS07355	COG1131	(ABC) transporter
A0W34_RS07365	COG2234	aminopeptidase activity
A0W34_RS07375	COG0351	phosphomethylpyrimidine kinase
A0W34_RS07390	COG0456	acetyltransferase
A0W34_RS07390	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A0W34_RS07415	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
A0W34_RS07425	COG1320	monovalent cation:proton antiporter activity
A0W34_RS07435	COG1863	multisubunit Na H antiporter MnhE subunit
A0W34_RS07440	COG0651	ATP synthesis coupled electron transport
A0W34_RS07445	COG1006	Multisubunit Na H antiporter MnhC subunit
A0W34_RS07450	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A0W34_RS07450	COG2111	Na H antiporter
A0W34_RS07480	COG2124	cytochrome p450
A0W34_RS07505	COG1228	amidohydrolase
A0W34_RS07510	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A0W34_RS07515	COG1183	phosphatidylcholine synthase activity
A0W34_RS07520	COG0688	phosphatidylethanolamine metabolic process
A0W34_RS07545	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A0W34_RS07565	COG2508	Transcriptional regulator
A0W34_RS07565	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
A0W34_RS07580	COG0459	protein refolding
A0W34_RS07600	COG2326	polyphosphate kinase activity
A0W34_RS07610	COG1505	serine-type exopeptidase activity
A0W34_RS07640	COG1733	regulation of RNA biosynthetic process
A0W34_RS07645	COG0702	epimerase
A0W34_RS07665	COG1802	Transcriptional regulator
A0W34_RS07675	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS07685	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A0W34_RS07715	COG1802	Transcriptional regulator
A0W34_RS07745	COG1309	transcriptional regulator
A0W34_RS07755	COG1172	Belongs to the binding-protein-dependent transport system permease family
A0W34_RS07765	COG1137	ATPase activity
A0W34_RS07775	COG0318	PFAM AMP-dependent synthetase and ligase
A0W34_RS07815	COG2224	Isocitrate lyase
A0W34_RS07825	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
A0W34_RS07830	COG1064	alcohol dehydrogenase
A0W34_RS07855	COG0297	glycogen (starch) synthase activity
A0W34_RS07875	COG2326	polyphosphate kinase activity
A0W34_RS07885	COG2733	membrane
A0W34_RS07905	COG0596	Alpha beta hydrolase
A0W34_RS07915	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
A0W34_RS07955	COG0812	UDP-N-acetylmuramate dehydrogenase activity
A0W34_RS08000	COG0583	DNA-binding transcription factor activity
A0W34_RS08015	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A0W34_RS08030	COG0438	transferase activity, transferring glycosyl groups
A0W34_RS08040	COG0318	PFAM AMP-dependent synthetase and ligase
A0W34_RS08050	COG5002	protein histidine kinase activity
A0W34_RS08055	COG0745	RESPONSE REGULATOR receiver
A0W34_RS08145	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
A0W34_RS08150	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
A0W34_RS08155	COG0181	hydroxymethylbilane synthase activity
A0W34_RS08160	COG1587	Uroporphyrinogen-III synthase
A0W34_RS08160	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
A0W34_RS08190	COG1937	Protein conserved in bacteria
A0W34_RS08200	COG1218	3'(2'),5'-bisphosphate nucleotidase
A0W34_RS08205	COG0175	sulfate reduction
A0W34_RS08220	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS08265	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
A0W34_RS08270	COG0406	alpha-ribazole phosphatase activity
A0W34_RS08280	COG0785	Cytochrome C biogenesis protein
A0W34_RS08290	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A0W34_RS08315	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A0W34_RS08335	COG0542	response to heat
A0W34_RS08340	COG1950	PFAM Membrane protein of
A0W34_RS08395	COG0559	Belongs to the binding-protein-dependent transport system permease family
A0W34_RS08405	COG0410	ABC transporter
A0W34_RS08430	COG4948	Mandelate Racemase Muconate Lactonizing
A0W34_RS08445	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A0W34_RS08450	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
A0W34_RS08460	COG0438	transferase activity, transferring glycosyl groups
A0W34_RS08470	COG0644	oxidoreductase
A0W34_RS08475	COG0142	geranyltranstransferase activity
A0W34_RS08480	COG0501	Belongs to the peptidase M48B family
A0W34_RS08485	COG1666	GTP binding
A0W34_RS08505	COG0267	Belongs to the bacterial ribosomal protein bL33 family
A0W34_RS08510	COG2030	dehydratase
A0W34_RS08535	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
A0W34_RS08540	COG0081	regulation of translation
A0W34_RS08550	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
A0W34_RS08565	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A0W34_RS08570	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A0W34_RS08595	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
A0W34_RS08615	COG0085	RNA polymerase activity
A0W34_RS08620	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
A0W34_RS08630	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A0W34_RS08650	COG0604	alcohol dehydrogenase
A0W34_RS08660	COG0604	alcohol dehydrogenase
A0W34_RS08670	COG0477	Major facilitator Superfamily
A0W34_RS08675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A0W34_RS08700	COG1024	Enoyl-CoA hydratase
A0W34_RS08715	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS08720	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A0W34_RS08755	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
A0W34_RS08760	COG0049	tRNA binding
A0W34_RS08765	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
A0W34_RS08770	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
A0W34_RS08805	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
A0W34_RS08865	COG1454	alcohol dehydrogenase
A0W34_RS08870	COG4585	Histidine kinase
A0W34_RS08890	COG1131	(ABC) transporter
A0W34_RS08895	COG3559	Exporter of polyketide antibiotics
A0W34_RS08940	COG0535	radical SAM domain protein
A0W34_RS08955	COG0446	pyridine nucleotide-disulphide oxidoreductase
A0W34_RS08955	COG1902	pentaerythritol trinitrate reductase activity
A0W34_RS08965	COG1902	pentaerythritol trinitrate reductase activity
A0W34_RS08965	COG0446	pyridine nucleotide-disulphide oxidoreductase
A0W34_RS09005	COG0531	amino acid
A0W34_RS09010	COG4303	Ethanolamine ammonia lyase large subunit
A0W34_RS09030	COG0477	Major facilitator Superfamily
A0W34_RS09035	COG0318	PFAM AMP-dependent synthetase and ligase
A0W34_RS09045	COG1012	belongs to the aldehyde dehydrogenase family
A0W34_RS09060	COG2409	Drug exporters of the RND superfamily
A0W34_RS09075	COG1216	Glycosyl transferase, family 2
A0W34_RS09080	COG1301	dicarboxylic acid transport
A0W34_RS09090	COG2357	RelA SpoT domain protein
A0W34_RS09095	COG1309	transcriptional regulator
A0W34_RS09100	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A0W34_RS09110	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS09115	COG2030	dehydratase
A0W34_RS09140	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A0W34_RS09150	COG1216	Glycosyl transferase, family 2
A0W34_RS09150	COG1442	glycosyl transferase family 8
A0W34_RS09160	COG5479	isomerase activity
A0W34_RS09160	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
A0W34_RS09185	COG0287	Prephenate dehydrogenase
A0W34_RS09190	COG0512	Glutamine amidotransferase of anthranilate synthase
A0W34_RS09190	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A0W34_RS09195	COG1605	Chorismate mutase
A0W34_RS09205	COG0051	transcription antitermination factor activity, RNA binding
A0W34_RS09210	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
A0W34_RS09215	COG0088	Forms part of the polypeptide exit tunnel
A0W34_RS09220	COG0089	rRNA binding
A0W34_RS09225	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
A0W34_RS09230	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
A0W34_RS09235	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
A0W34_RS09240	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
A0W34_RS09245	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
A0W34_RS09250	COG0255	Belongs to the universal ribosomal protein uL29 family
A0W34_RS09255	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
A0W34_RS09260	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
A0W34_RS09265	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
A0W34_RS09270	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
A0W34_RS09275	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
A0W34_RS09280	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
A0W34_RS09285	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
A0W34_RS09290	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
A0W34_RS09295	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
A0W34_RS09300	COG1841	ribosomal large subunit assembly
A0W34_RS09305	COG0200	Binds to the 23S rRNA
A0W34_RS09310	COG0201	protein transport
A0W34_RS09315	COG0563	adenylate kinase activity
A0W34_RS09325	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
A0W34_RS09330	COG0257	Belongs to the bacterial ribosomal protein bL36 family
A0W34_RS09335	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
A0W34_RS09340	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
A0W34_RS09345	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
A0W34_RS09350	COG0202	RNA polymerase activity
A0W34_RS09355	COG0203	ribosomal protein L17
A0W34_RS09360	COG0101	tRNA pseudouridine synthase activity
A0W34_RS09365	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS09390	COG1404	Belongs to the peptidase S8 family
A0W34_RS09400	COG1674	ftsk spoiiie
A0W34_RS09475	COG1388	LysM domain
A0W34_RS09475	COG0791	NLP P60 protein
A0W34_RS09505	COG1674	ftsk spoiiie
A0W34_RS09525	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
A0W34_RS09530	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
A0W34_RS09535	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A0W34_RS09560	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A0W34_RS09575	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A0W34_RS09595	COG0456	acetyltransferase
A0W34_RS09600	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
A0W34_RS09620	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
A0W34_RS09625	COG0459	protein refolding
A0W34_RS09675	COG0516	GMP reductase activity
A0W34_RS09695	COG0519	Catalyzes the synthesis of GMP from XMP
A0W34_RS09695	COG0518	GMP synthase (glutamine-hydrolyzing) activity
A0W34_RS09725	COG2271	Major facilitator Superfamily
A0W34_RS09730	COG2205	protein histidine kinase activity
A0W34_RS09735	COG0745	RESPONSE REGULATOR receiver
A0W34_RS09750	COG1733	regulation of RNA biosynthetic process
A0W34_RS09765	COG2815	serine threonine protein kinase
A0W34_RS09765	COG0515	serine threonine protein kinase
A0W34_RS09795	COG3119	arylsulfatase activity
A0W34_RS09800	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A0W34_RS09850	COG2249	NAD(P)H dehydrogenase (quinone) activity
A0W34_RS09860	COG0583	DNA-binding transcription factor activity
A0W34_RS09880	COG4221	oxidoreductase activity
A0W34_RS09905	COG1120	ATPase activity
A0W34_RS09920	COG0587	DNA-directed DNA polymerase activity
A0W34_RS09930	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS09935	COG3321	synthase
A0W34_RS09935	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS09935	COG0604	alcohol dehydrogenase
A0W34_RS09985	COG0243	molybdopterin cofactor binding
A0W34_RS09990	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
A0W34_RS10015	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
A0W34_RS10030	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A0W34_RS10035	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
A0W34_RS10040	COG2873	o-acetylhomoserine
A0W34_RS10055	COG0708	Exodeoxyribonuclease III
A0W34_RS10070	COG0180	Tryptophanyl-tRNA synthetase
A0W34_RS10075	COG1295	ribonuclease BN
A0W34_RS10080	COG1686	Belongs to the peptidase S11 family
A0W34_RS10100	COG1082	Xylose isomerase domain protein TIM barrel
A0W34_RS10105	COG0673	inositol 2-dehydrogenase activity
A0W34_RS10115	COG3962	Belongs to the TPP enzyme family
A0W34_RS10120	COG3718	enzyme involved in inositol metabolism
A0W34_RS10135	COG2188	Transcriptional regulator
A0W34_RS10145	COG2814	Major facilitator Superfamily
A0W34_RS10150	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A0W34_RS10155	COG0242	peptide deformylase activity
A0W34_RS10170	COG0673	inositol 2-dehydrogenase activity
A0W34_RS10175	COG3622	Belongs to the hyi family
A0W34_RS10180	COG0673	inositol 2-dehydrogenase activity
A0W34_RS10185	COG1609	Transcriptional regulator
A0W34_RS10195	COG1172	Belongs to the binding-protein-dependent transport system permease family
A0W34_RS10215	COG0673	inositol 2-dehydrogenase activity
A0W34_RS10220	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS10230	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
A0W34_RS10235	COG1053	succinate dehydrogenase
A0W34_RS10245	COG2009	succinate dehydrogenase
A0W34_RS10280	COG0741	lytic transglycosylase activity
A0W34_RS10280	COG0791	NLP P60 protein
A0W34_RS10290	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
A0W34_RS10295	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A0W34_RS10315	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
A0W34_RS10315	COG1473	amidohydrolase
A0W34_RS10340	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
A0W34_RS10345	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
A0W34_RS10350	COG0583	DNA-binding transcription factor activity
A0W34_RS10355	COG0477	Major facilitator Superfamily
A0W34_RS10360	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
A0W34_RS10390	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS10425	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
A0W34_RS10430	COG1201	RNA secondary structure unwinding
A0W34_RS10435	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
A0W34_RS10455	COG2233	PERMEase
A0W34_RS10460	COG3491	Belongs to the iron ascorbate-dependent oxidoreductase family
A0W34_RS10470	COG1012	belongs to the aldehyde dehydrogenase family
A0W34_RS10480	COG1522	sequence-specific DNA binding
A0W34_RS10490	COG1529	Aldehyde oxidase and xanthine dehydrogenase
A0W34_RS10510	COG2351	hydroxyisourate hydrolase activity
A0W34_RS10540	COG4770	biotin carboxylase activity
A0W34_RS10570	COG0477	Major facilitator Superfamily
A0W34_RS10580	COG0424	maF-like protein
A0W34_RS10590	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A0W34_RS10595	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
A0W34_RS10595	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
A0W34_RS10610	COG0745	RESPONSE REGULATOR receiver
A0W34_RS10615	COG2205	protein histidine kinase activity
A0W34_RS10625	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
A0W34_RS10640	COG4585	Histidine kinase
A0W34_RS10645	COG2197	response regulator
A0W34_RS10650	COG1136	(ABC) transporter
A0W34_RS10650	COG0577	efflux transmembrane transporter activity
A0W34_RS10665	COG1316	TRANSCRIPTIONal
A0W34_RS10680	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
A0W34_RS10695	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
A0W34_RS10695	COG0778	Nitroreductase
A0W34_RS10720	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A0W34_RS10730	COG1482	cell wall glycoprotein biosynthetic process
A0W34_RS10740	COG0531	amino acid
A0W34_RS10745	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A0W34_RS10780	COG5002	protein histidine kinase activity
A0W34_RS10785	COG5401	PFAM Sporulation and spore germination
A0W34_RS10795	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
A0W34_RS10800	COG0653	protein targeting
A0W34_RS10840	COG1162	GTPase activity
A0W34_RS10845	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
A0W34_RS10875	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
A0W34_RS10890	COG1597	lipid kinase activity
A0W34_RS10905	COG0406	alpha-ribazole phosphatase activity
A0W34_RS10910	COG1192	Involved in chromosome partitioning
A0W34_RS10920	COG0513	Belongs to the DEAD box helicase family
A0W34_RS10955	COG2186	Transcriptional regulator
A0W34_RS10970	COG2146	nitrite reductase [NAD(P)H] activity
A0W34_RS10970	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A0W34_RS10975	COG2146	nitrite reductase [NAD(P)H] activity
A0W34_RS10975	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A0W34_RS11020	COG0596	Alpha beta hydrolase
A0W34_RS11025	COG0210	DNA helicase
A0W34_RS11065	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
A0W34_RS11080	COG3480	Lon protease (S16) C-terminal proteolytic domain
A0W34_RS11090	COG1615	UPF0182 protein
A0W34_RS11095	COG1388	LysM domain
A0W34_RS11120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A0W34_RS11140	COG0402	S-adenosylhomocysteine deaminase activity
A0W34_RS11145	COG0318	PFAM AMP-dependent synthetase and ligase
A0W34_RS11150	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS11160	COG3851	Histidine kinase
A0W34_RS11165	COG2197	response regulator
A0W34_RS11170	COG2132	Multicopper oxidase
A0W34_RS11175	COG0483	inositol monophosphate 1-phosphatase activity
A0W34_RS11185	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
A0W34_RS11190	COG0668	transmembrane transport
A0W34_RS11200	COG2884	Cell division ATP-binding protein ftsE
A0W34_RS11205	COG2177	Part of the ABC transporter FtsEX involved in
A0W34_RS11210	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
A0W34_RS11230	COG0702	epimerase
A0W34_RS11240	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
A0W34_RS11270	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A0W34_RS11275	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A0W34_RS11285	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A0W34_RS11290	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A0W34_RS11340	COG0778	Nitroreductase
A0W34_RS11345	COG0513	Belongs to the DEAD box helicase family
A0W34_RS11355	COG0521	Mo-molybdopterin cofactor biosynthetic process
A0W34_RS11355	COG0315	cyclic pyranopterin monophosphate synthase activity
A0W34_RS11365	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A0W34_RS11380	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
A0W34_RS11395	COG1309	transcriptional regulator
A0W34_RS11415	COG1780	Probably involved in ribonucleotide reductase function
A0W34_RS11420	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A0W34_RS11440	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A0W34_RS11445	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A0W34_RS11460	COG2364	Membrane
A0W34_RS11470	COG1119	ATPase activity
A0W34_RS11485	COG2226	methyltransferase
A0W34_RS11500	COG0110	maltose O-acetyltransferase activity
A0W34_RS11520	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A0W34_RS11530	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
A0W34_RS11550	COG0482	sulfurtransferase activity
A0W34_RS11560	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
A0W34_RS11575	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A0W34_RS11580	COG0154	amidase activity
A0W34_RS11595	COG4585	Histidine kinase
A0W34_RS11600	COG2197	response regulator
A0W34_RS11605	COG0205	6-phosphofructokinase activity
A0W34_RS11610	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A0W34_RS11625	COG2259	Doxx family
A0W34_RS11630	COG0531	amino acid
A0W34_RS11635	COG0129	dihydroxy-acid dehydratase activity
A0W34_RS11650	COG0440	acetolactate synthase activity
A0W34_RS11655	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
A0W34_RS11665	COG0473	3-isopropylmalate dehydrogenase activity
A0W34_RS11670	COG0179	Fumarylacetoacetate (FAA) hydrolase
A0W34_RS11675	COG3239	Fatty acid desaturase
A0W34_RS11680	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A0W34_RS11705	COG1414	Transcriptional regulator
A0W34_RS11710	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
A0W34_RS11715	COG0066	3-isopropylmalate dehydratase activity
A0W34_RS11730	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
A0W34_RS11735	COG1920	GTP binding
A0W34_RS11740	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
A0W34_RS11745	COG0626	cystathionine gamma-synthase activity
A0W34_RS11750	COG1181	Belongs to the D-alanine--D-alanine ligase family
A0W34_RS11770	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
A0W34_RS11780	COG0227	Belongs to the bacterial ribosomal protein bL28 family
A0W34_RS11785	COG1461	Dihydroxyacetone kinase
A0W34_RS11790	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A0W34_RS11795	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
A0W34_RS11800	COG0742	ribosomal rna small subunit methyltransferase
A0W34_RS11805	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
A0W34_RS11820	COG0333	Belongs to the bacterial ribosomal protein bL32 family
A0W34_RS11825	COG0571	ribonuclease III activity
A0W34_RS11830	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
A0W34_RS11845	COG1254	Belongs to the acylphosphatase family
A0W34_RS11850	COG1196	nuclear chromosome segregation
A0W34_RS11870	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
A0W34_RS11885	COG0228	four-way junction DNA binding
A0W34_RS11895	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
A0W34_RS11900	COG0336	Belongs to the RNA methyltransferase TrmD family
A0W34_RS11925	COG0463	Glycosyl transferase, family 2
A0W34_RS11930	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
A0W34_RS11950	COG0335	large ribosomal subunit rRNA binding
A0W34_RS11955	COG0681	Belongs to the peptidase S26 family
A0W34_RS11960	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
A0W34_RS11970	COG1690	Belongs to the RtcB family
A0W34_RS12045	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A0W34_RS12050	COG0792	nuclease activity
A0W34_RS12075	COG2814	Major facilitator Superfamily
A0W34_RS12095	COG0052	Belongs to the universal ribosomal protein uS2 family
A0W34_RS12100	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
A0W34_RS12105	COG0528	UMP kinase activity
A0W34_RS12110	COG0233	cytoplasmic translational termination
A0W34_RS12115	COG0575	Belongs to the CDS family
A0W34_RS12120	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A0W34_RS12135	COG0820	rRNA (adenine-C2-)-methyltransferase activity
A0W34_RS12145	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
A0W34_RS12150	COG0750	zinc metalloprotease
A0W34_RS12170	COG2197	response regulator
A0W34_RS12175	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A0W34_RS12210	COG2188	Transcriptional regulator
A0W34_RS12245	COG1760	l-serine dehydratase
A0W34_RS12275	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
A0W34_RS12315	COG2207	Transcriptional regulator
A0W34_RS12320	COG2076	Multidrug Resistance protein
A0W34_RS12340	COG1492	cobalamin metabolic process
A0W34_RS12360	COG0384	phenazine biosynthesis protein PhzF
A0W34_RS12365	COG3467	pyridoxamine 5'-phosphate
A0W34_RS12385	COG0579	oxidoreductase
A0W34_RS12415	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
A0W34_RS12415	COG1648	precorrin-2 dehydrogenase activity
A0W34_RS12425	COG0517	IMP dehydrogenase activity
A0W34_RS12430	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
A0W34_RS12435	COG3022	response to hydroperoxide
A0W34_RS12440	COG0442	prolyl-tRNA aminoacylation
A0W34_RS12445	COG4122	O-methyltransferase activity
A0W34_RS12475	COG0697	spore germination
A0W34_RS12480	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS12495	COG0477	Major facilitator Superfamily
A0W34_RS12510	COG0779	Required for maturation of 30S ribosomal subunits
A0W34_RS12525	COG0481	GTPase activity
A0W34_RS12525	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
A0W34_RS12535	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
A0W34_RS12540	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
A0W34_RS12550	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
A0W34_RS12560	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
A0W34_RS12580	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
A0W34_RS12585	COG1185	polyribonucleotide nucleotidyltransferase activity
A0W34_RS12605	COG0375	protein maturation
A0W34_RS12625	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
A0W34_RS12655	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
A0W34_RS12660	COG0298	carbon dioxide binding
A0W34_RS12665	COG0409	Hydrogenase expression formation protein
A0W34_RS12670	COG0309	Hydrogenase expression formation protein (HypE)
A0W34_RS12710	COG0657	acetylesterase activity
A0W34_RS12715	COG3835	regulator
A0W34_RS12735	COG2365	Tyrosine phosphatase family
A0W34_RS12755	COG0789	Transcriptional regulator
A0W34_RS12760	COG0095	Lipoate-protein ligase
A0W34_RS12790	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
A0W34_RS12820	COG1535	isochorismatase
A0W34_RS12820	COG3433	isochorismatase activity
A0W34_RS12825	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS12830	COG1021	2,3-dihydroxybenzoate-AMP ligase
A0W34_RS12835	COG3433	isochorismatase activity
A0W34_RS12835	COG1535	isochorismatase
A0W34_RS12845	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A0W34_RS12850	COG4592	Periplasmic binding protein
A0W34_RS12860	COG2375	cellular response to nickel ion
A0W34_RS12880	COG1131	(ABC) transporter
A0W34_RS12925	COG0713	ATP synthesis coupled electron transport
A0W34_RS12935	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A0W34_RS12940	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
A0W34_RS12945	COG1034	ATP synthesis coupled electron transport
A0W34_RS12960	COG0649	NAD binding
A0W34_RS12970	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A0W34_RS13010	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A0W34_RS13035	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
A0W34_RS13045	COG1058	Belongs to the CinA family
A0W34_RS13045	COG1546	Belongs to the CinA family
A0W34_RS13050	COG1396	sequence-specific DNA binding
A0W34_RS13055	COG1842	Phage shock protein A
A0W34_RS13065	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
A0W34_RS13070	COG1122	ATPase activity
A0W34_RS13075	COG1268	BioY protein
A0W34_RS13105	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
A0W34_RS13110	COG2137	regulation of response to DNA damage stimulus
A0W34_RS13115	COG0765	amino acid transport
A0W34_RS13120	COG0765	amino acid transport
A0W34_RS13125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A0W34_RS13130	COG1126	abc transporter atp-binding protein
A0W34_RS13135	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A0W34_RS13145	COG1196	nuclear chromosome segregation
A0W34_RS13155	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
A0W34_RS13165	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
A0W34_RS13170	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A0W34_RS13180	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
A0W34_RS13185	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A0W34_RS13190	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A0W34_RS13190	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A0W34_RS13190	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
A0W34_RS13195	COG1105	Belongs to the carbohydrate kinase PfkB family
A0W34_RS13200	COG1349	DNA-binding transcription factor activity
A0W34_RS13205	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A0W34_RS13210	COG2233	PERMEase
A0W34_RS13215	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS13225	COG1388	LysM domain
A0W34_RS13230	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
A0W34_RS13235	COG1643	Atp-dependent helicase
A0W34_RS13270	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A0W34_RS13275	COG0450	alkyl hydroperoxide reductase
A0W34_RS13285	COG0277	FAD linked oxidase domain protein
A0W34_RS13335	COG0123	including yeast histone deacetylase and acetoin utilization protein
A0W34_RS13340	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A0W34_RS13340	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A0W34_RS13350	COG2813	Specifically methylates the guanine in position
A0W34_RS13395	COG0475	glutathione-regulated potassium exporter activity
A0W34_RS13400	COG2365	Tyrosine phosphatase family
A0W34_RS13415	COG0483	inositol monophosphate 1-phosphatase activity
A0W34_RS13435	COG0756	dUTP diphosphatase activity
A0W34_RS13470	COG0569	domain protein
A0W34_RS13475	COG0531	amino acid
A0W34_RS13480	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A0W34_RS13490	COG0477	Major facilitator Superfamily
A0W34_RS13500	COG2066	Belongs to the glutaminase family
A0W34_RS13500	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
A0W34_RS13505	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
A0W34_RS13510	COG0477	Major facilitator Superfamily
A0W34_RS13530	COG1024	Enoyl-CoA hydratase
A0W34_RS13530	COG1250	3-hydroxyacyl-CoA dehydrogenase
A0W34_RS13535	COG0183	Belongs to the thiolase family
A0W34_RS13555	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
A0W34_RS13590	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A0W34_RS13620	COG2223	nitrite transmembrane transporter activity
A0W34_RS13625	COG2723	6-phospho-beta-galactosidase activity
A0W34_RS13880	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
A0W34_RS13895	COG1560	Kdo2-lipid A biosynthetic process
A0W34_RS13900	COG0438	transferase activity, transferring glycosyl groups
A0W34_RS13905	COG1051	belongs to the nudix hydrolase family
A0W34_RS13910	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
A0W34_RS13930	COG1946	Acyl-CoA thioesterase
A0W34_RS13940	COG1946	Acyl-CoA thioesterase
A0W34_RS13950	COG2197	response regulator
A0W34_RS13955	COG4585	Histidine kinase
A0W34_RS13975	COG2188	Transcriptional regulator
A0W34_RS13980	COG0217	transcriptional regulatory protein
A0W34_RS13985	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
A0W34_RS13990	COG0632	four-way junction helicase activity
A0W34_RS13995	COG2255	four-way junction helicase activity
A0W34_RS14010	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A0W34_RS14015	COG0747	negative chemotaxis
A0W34_RS14020	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A0W34_RS14025	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A0W34_RS14030	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A0W34_RS14035	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A0W34_RS14045	COG0124	histidyl-tRNA synthetase
A0W34_RS14055	COG0039	L-malate dehydrogenase activity
A0W34_RS14080	COG1131	(ABC) transporter
A0W34_RS14100	COG1053	succinate dehydrogenase
A0W34_RS14105	COG0488	(ABC) transporter
A0W34_RS14115	COG1652	LysM domain
A0W34_RS14145	COG2184	nucleotidyltransferase activity
A0W34_RS14175	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
A0W34_RS14205	COG0662	Cupin 2, conserved barrel domain protein
A0W34_RS14225	COG1309	transcriptional regulator
A0W34_RS14230	COG2824	Alkylphosphonate utilization operon protein PhnA
A0W34_RS14265	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
A0W34_RS14290	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A0W34_RS14295	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
A0W34_RS14305	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
A0W34_RS14320	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
A0W34_RS14325	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
A0W34_RS14330	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
A0W34_RS14350	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
A0W34_RS14355	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A0W34_RS14360	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
A0W34_RS14365	COG0540	Belongs to the ATCase OTCase family
A0W34_RS14380	COG0505	Belongs to the CarA family
A0W34_RS14390	COG0284	orotidine-5'-phosphate decarboxylase activity
A0W34_RS14395	COG1051	belongs to the nudix hydrolase family
A0W34_RS14405	COG0194	GDP metabolic process
A0W34_RS14410	COG1758	RNA polymerase activity
A0W34_RS14420	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
A0W34_RS14450	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
A0W34_RS14480	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A0W34_RS14480	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A0W34_RS14495	COG0322	excinuclease ABC activity
A0W34_RS14500	COG1660	Displays ATPase and GTPase activities
A0W34_RS14515	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A0W34_RS14520	COG0126	phosphoglycerate kinase activity
A0W34_RS14525	COG0149	triose-phosphate isomerase activity
A0W34_RS14530	COG2365	Tyrosine phosphatase family
A0W34_RS14540	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
A0W34_RS14545	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS14565	COG1129	ABC transporter
A0W34_RS14575	COG4221	oxidoreductase activity
A0W34_RS14595	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A0W34_RS14605	COG0109	protoheme IX farnesyltransferase activity
A0W34_RS14625	COG4974	Belongs to the 'phage' integrase family
A0W34_RS14675	COG0396	ATPase activity
A0W34_RS14685	COG0822	iron-sulfur transferase activity
A0W34_RS14700	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
A0W34_RS14715	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS14720	COG0488	(ABC) transporter
A0W34_RS14725	COG1309	transcriptional regulator
A0W34_RS14730	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
A0W34_RS14745	COG3883	PFAM NLP P60 protein
A0W34_RS14745	COG0791	NLP P60 protein
A0W34_RS14750	COG0714	Associated with various cellular activities
A0W34_RS14760	COG2304	oxidoreductase activity
A0W34_RS14775	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
A0W34_RS14795	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
A0W34_RS14795	COG1024	Enoyl-CoA hydratase
A0W34_RS14850	COG0730	response to heat
A0W34_RS14875	COG1253	flavin adenine dinucleotide binding
A0W34_RS14880	COG1253	flavin adenine dinucleotide binding
A0W34_RS14895	COG0697	spore germination
A0W34_RS14900	COG0513	Belongs to the DEAD box helicase family
A0W34_RS14905	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
A0W34_RS14910	COG0513	Belongs to the DEAD box helicase family
A0W34_RS14925	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
A0W34_RS14930	COG1120	ATPase activity
A0W34_RS14935	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A0W34_RS14940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A0W34_RS14955	COG1252	NADH dehydrogenase
A0W34_RS14960	COG0640	Transcriptional regulator
A0W34_RS14990	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A0W34_RS15000	COG5001	Diguanylate cyclase
A0W34_RS15000	COG3300	MHYT domain
A0W34_RS15065	COG2197	response regulator
A0W34_RS15070	COG4585	Histidine kinase
A0W34_RS15090	COG1090	epimerase
A0W34_RS15150	COG4762	Protein conserved in bacteria
A0W34_RS15165	COG2205	protein histidine kinase activity
A0W34_RS15180	COG2241	protein methyltransferase activity
A0W34_RS15180	COG2242	protein methyltransferase activity
A0W34_RS15185	COG0300	oxidoreductase activity
A0W34_RS15220	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A0W34_RS15225	COG2378	regulation of single-species biofilm formation
A0W34_RS15235	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
A0W34_RS15250	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
A0W34_RS15275	COG1222	aaa ATPase
A0W34_RS15290	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
A0W34_RS15300	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
A0W34_RS15305	COG0140	phosphoribosyl-ATP diphosphatase activity
A0W34_RS15315	COG1054	Belongs to the UPF0176 family
A0W34_RS15325	COG0646	methionine synthase
A0W34_RS15325	COG1410	methionine synthase
A0W34_RS15365	COG0215	cysteine-tRNA ligase activity
A0W34_RS15370	COG2409	Drug exporters of the RND superfamily
A0W34_RS15395	COG1968	undecaprenyl-diphosphatase activity
A0W34_RS15400	COG0667	Aldo Keto reductase
A0W34_RS15415	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A0W34_RS15420	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
A0W34_RS15440	COG0167	dihydroorotate dehydrogenase activity
A0W34_RS15450	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A0W34_RS15475	COG3268	Saccharopine dehydrogenase
A0W34_RS15480	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
A0W34_RS15490	COG1408	metallophosphoesterase
A0W34_RS15515	COG1716	ATPase activity
A0W34_RS15550	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
A0W34_RS15560	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
A0W34_RS15570	COG0351	phosphomethylpyrimidine kinase
A0W34_RS15600	COG0444	Belongs to the ABC transporter superfamily
A0W34_RS15605	COG4608	Belongs to the ABC transporter superfamily
A0W34_RS15610	COG0747	negative chemotaxis
A0W34_RS15620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A0W34_RS15655	COG1160	GTP binding
A0W34_RS15660	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
A0W34_RS15670	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
A0W34_RS15675	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
A0W34_RS15690	COG0494	nUDIX hydrolase
A0W34_RS15695	COG0504	CTP synthase activity
A0W34_RS15715	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A0W34_RS15730	COG0647	UMP catabolic process
A0W34_RS15755	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
A0W34_RS15760	COG2094	Belongs to the DNA glycosylase MPG family
A0W34_RS15765	COG1131	(ABC) transporter
A0W34_RS15780	COG2835	tetraacyldisaccharide 4'-kinase activity
A0W34_RS15790	COG0165	Argininosuccinate lyase
A0W34_RS15795	COG0137	argininosuccinate synthase activity
A0W34_RS15800	COG1438	arginine binding
A0W34_RS15805	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
A0W34_RS15810	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A0W34_RS15815	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
A0W34_RS15820	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
A0W34_RS15825	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
A0W34_RS15835	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A0W34_RS15840	COG0385	Bile acid
A0W34_RS15845	COG2072	flavoprotein involved in K transport
A0W34_RS15855	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A0W34_RS15855	COG0072	phenylalanine-tRNA ligase activity
A0W34_RS15860	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
A0W34_RS15870	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
A0W34_RS15875	COG0291	Belongs to the bacterial ribosomal protein bL35 family
A0W34_RS15910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A0W34_RS15955	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
A0W34_RS15955	COG0237	dephospho-CoA kinase activity
A0W34_RS15965	COG0539	negative regulation of cytoplasmic translation
A0W34_RS15970	COG2226	methyltransferase
A0W34_RS15970	COG1073	alpha beta
A0W34_RS15985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A0W34_RS15990	COG0473	3-isopropylmalate dehydrogenase activity
A0W34_RS16015	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A0W34_RS16025	COG1172	Belongs to the binding-protein-dependent transport system permease family
A0W34_RS16065	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
A0W34_RS16075	COG1946	Acyl-CoA thioesterase
A0W34_RS16090	COG0067	glutamate synthase
A0W34_RS16090	COG0070	glutamate synthase
A0W34_RS16090	COG0069	glutamate synthase activity
A0W34_RS16105	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
A0W34_RS16110	COG0159	tryptophan synthase activity
A0W34_RS16120	COG0134	indole-3-glycerol-phosphate synthase activity
A0W34_RS16130	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A0W34_RS16140	COG3384	dioxygenase
A0W34_RS16150	COG1053	succinate dehydrogenase
A0W34_RS16175	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
A0W34_RS16200	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A0W34_RS16210	COG2124	cytochrome p450
A0W34_RS16255	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS16280	COG1053	succinate dehydrogenase
A0W34_RS16305	COG2080	2 iron, 2 sulfur cluster binding
A0W34_RS16305	COG1529	Aldehyde oxidase and xanthine dehydrogenase
A0W34_RS16320	COG2132	Multicopper oxidase
A0W34_RS16335	COG0640	Transcriptional regulator
A0W34_RS16340	COG0748	coenzyme F420 binding
A0W34_RS16360	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
A0W34_RS16370	COG2072	flavoprotein involved in K transport
A0W34_RS16380	COG0107	imidazoleglycerol-phosphate synthase activity
A0W34_RS16385	COG0483	inositol monophosphate 1-phosphatase activity
A0W34_RS16390	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
A0W34_RS16400	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
A0W34_RS16410	COG0131	Imidazoleglycerol-phosphate dehydratase
A0W34_RS16420	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
A0W34_RS16465	COG1280	lysine exporter protein (LysE YggA)
A0W34_RS16480	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A0W34_RS16485	COG0076	glutamate decarboxylase activity
A0W34_RS16505	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A0W34_RS16505	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A0W34_RS16515	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A0W34_RS16520	COG1510	regulation of RNA biosynthetic process
A0W34_RS16530	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
A0W34_RS16545	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A0W34_RS16585	COG4221	oxidoreductase activity
A0W34_RS16600	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
A0W34_RS16665	COG2199	diguanylate cyclase activity
A0W34_RS16670	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
A0W34_RS16680	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A0W34_RS16695	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS16700	COG3321	synthase
A0W34_RS16700	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS16700	COG0604	alcohol dehydrogenase
A0W34_RS16710	COG1309	transcriptional regulator
A0W34_RS16715	COG5006	permease, DMT superfamily
A0W34_RS16740	COG0477	Major facilitator Superfamily
A0W34_RS16750	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A0W34_RS16755	COG0798	PFAM Bile acid sodium symporter
A0W34_RS16760	COG0640	Transcriptional regulator
A0W34_RS16780	COG0477	Major facilitator Superfamily
A0W34_RS16795	COG0028	Belongs to the TPP enzyme family
A0W34_RS16830	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
A0W34_RS16845	COG2072	flavoprotein involved in K transport
A0W34_RS16860	COG0477	Major facilitator Superfamily
A0W34_RS16865	COG0300	oxidoreductase activity
A0W34_RS16870	COG2149	membrane
A0W34_RS16880	COG0076	glutamate decarboxylase activity
A0W34_RS16900	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
A0W34_RS16910	COG3599	regulation of cell shape
A0W34_RS16925	COG1799	cell septum assembly
A0W34_RS16935	COG1496	oxidoreductase activity
A0W34_RS16940	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A0W34_RS16945	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
A0W34_RS16950	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
A0W34_RS16955	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
A0W34_RS16965	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
A0W34_RS16985	COG0768	penicillin binding
A0W34_RS16995	COG0275	rRNA processing
A0W34_RS17000	COG2001	Belongs to the MraZ family
A0W34_RS17040	COG0142	geranyltranstransferase activity
A0W34_RS17075	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
A0W34_RS17090	COG1940	carbohydrate kinase activity
A0W34_RS17100	COG0003	Pfam Anion-transporting ATPase
A0W34_RS17110	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A0W34_RS17135	COG0791	NLP P60 protein
A0W34_RS17150	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A0W34_RS17160	COG1845	cytochrome c oxidase, subunit III
A0W34_RS17180	COG2329	Antibiotic biosynthesis monooxygenase
A0W34_RS17195	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
A0W34_RS17205	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A0W34_RS17225	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
A0W34_RS17230	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
A0W34_RS17235	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
A0W34_RS17250	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A0W34_RS17255	COG0404	The glycine cleavage system catalyzes the degradation of glycine
A0W34_RS17260	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
A0W34_RS17280	COG0321	lipoyl(octanoyl) transferase activity
A0W34_RS17285	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
A0W34_RS17300	COG0174	glutamine synthetase
A0W34_RS17315	COG2267	carboxylic ester hydrolase activity
A0W34_RS17380	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
A0W34_RS17420	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
A0W34_RS17425	COG0174	glutamine synthetase
A0W34_RS17435	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
A0W34_RS17470	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A0W34_RS17485	COG3323	Protein of unknown function (DUF1653)
A0W34_RS17485	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
A0W34_RS17510	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
A0W34_RS17545	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
A0W34_RS17560	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A0W34_RS17565	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A0W34_RS17595	COG2197	response regulator
A0W34_RS17600	COG4585	Histidine kinase
A0W34_RS17605	COG2409	Drug exporters of the RND superfamily
A0W34_RS17610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A0W34_RS17615	COG3842	ATPase activity
A0W34_RS17620	COG0395	ABC-type sugar transport system, permease component
A0W34_RS17640	COG1063	alcohol dehydrogenase
A0W34_RS17705	COG0232	Belongs to the dGTPase family. Type 2 subfamily
A0W34_RS17720	COG0463	Glycosyl transferase, family 2
A0W34_RS17745	COG0423	glycine-tRNA ligase activity
A0W34_RS17765	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
A0W34_RS17770	COG1381	Involved in DNA repair and RecF pathway recombination
A0W34_RS17795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A0W34_RS17800	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A0W34_RS17810	COG1063	alcohol dehydrogenase
A0W34_RS17825	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
A0W34_RS17830	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
A0W34_RS17835	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
A0W34_RS17865	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
A0W34_RS17880	COG0477	Major facilitator Superfamily
A0W34_RS17890	COG1376	ErfK ybiS ycfS ynhG family protein
A0W34_RS17900	COG0484	heat shock protein binding
A0W34_RS17905	COG1420	regulation of RNA biosynthetic process
A0W34_RS17935	COG0175	sulfate reduction
A0W34_RS17965	COG3842	ATPase activity
A0W34_RS17970	COG4208	sulfate ABC transporter
A0W34_RS17990	COG3387	PFAM Glycoside hydrolase 15-related
A0W34_RS17995	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A0W34_RS18000	COG2070	2-Nitropropane dioxygenase
A0W34_RS18015	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A0W34_RS18020	COG1305	Transglutaminase-like
A0W34_RS18030	COG2308	Evidence 4 Homologs of previously reported genes of
A0W34_RS18035	COG0268	Binds directly to 16S ribosomal RNA
A0W34_RS18050	COG0658	competence protein
A0W34_RS18050	COG2333	competence protein COMEC
A0W34_RS18065	COG2755	lipolytic protein G-D-S-L family
A0W34_RS18070	COG0406	alpha-ribazole phosphatase activity
A0W34_RS18080	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
A0W34_RS18090	COG0542	response to heat
A0W34_RS18095	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
A0W34_RS18100	COG1902	pentaerythritol trinitrate reductase activity
A0W34_RS18110	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A0W34_RS18120	COG0514	ATP-dependent DNA helicase (RecQ)
A0W34_RS18125	COG0456	acetyltransferase
A0W34_RS18130	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A0W34_RS18135	COG1917	Cupin 2, conserved barrel domain protein
A0W34_RS18140	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A0W34_RS18160	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A0W34_RS18165	COG0211	Belongs to the bacterial ribosomal protein bL27 family
A0W34_RS18170	COG0261	This protein binds to 23S rRNA in the presence of protein L20
A0W34_RS18175	COG1530	ribonuclease E activity
A0W34_RS18175	COG1530	ribonuclease E activity
A0W34_RS18180	COG0105	UTP biosynthetic process
A0W34_RS18190	COG0285	dihydrofolate synthase activity
A0W34_RS18195	COG0525	valine-tRNA ligase activity
A0W34_RS18205	COG4946	Tricorn protease homolog
A0W34_RS18205	COG1506	peptidase
A0W34_RS18205	COG0823	Involved in the tonB-independent uptake of proteins
A0W34_RS18225	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
A0W34_RS18230	COG1082	Xylose isomerase domain protein TIM barrel
A0W34_RS18230	COG3185	4-Hydroxyphenylpyruvate dioxygenase
A0W34_RS18235	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
A0W34_RS18240	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
A0W34_RS18245	COG1309	transcriptional regulator
A0W34_RS18255	COG0477	Major facilitator Superfamily
A0W34_RS18260	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
A0W34_RS18265	COG0740	serine-type endopeptidase activity
A0W34_RS18270	COG0740	serine-type endopeptidase activity
A0W34_RS18275	COG0544	peptidyl-prolyl cis-trans isomerase activity
A0W34_RS18310	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
A0W34_RS18325	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
A0W34_RS18365	COG2902	Dehydrogenase
A0W34_RS18385	COG1132	(ABC) transporter
A0W34_RS18390	COG1846	Transcriptional regulator
A0W34_RS18400	COG3336	cytochrome c oxidase
A0W34_RS18435	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A0W34_RS18465	COG0596	Alpha beta hydrolase
A0W34_RS18485	COG0446	pyridine nucleotide-disulphide oxidoreductase
A0W34_RS18485	COG1902	pentaerythritol trinitrate reductase activity
A0W34_RS18490	COG0300	oxidoreductase activity
A0W34_RS18505	COG0433	COG0433 Predicted ATPase
A0W34_RS18510	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
A0W34_RS18520	COG0789	Transcriptional regulator
A0W34_RS18530	COG1376	ErfK ybiS ycfS ynhG family protein
A0W34_RS18570	COG0736	holo-[acyl-carrier-protein] synthase activity
A0W34_RS18605	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
A0W34_RS18610	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
A0W34_RS18615	COG1234	tRNA 3'-trailer cleavage
A0W34_RS18625	COG3191	aminopeptidase activity
A0W34_RS18635	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
A0W34_RS18640	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
A0W34_RS18645	COG1335	isochorismatase
A0W34_RS18655	COG0058	SHG alpha-glucan phosphorylase activity
A0W34_RS18660	COG0366	Alpha amylase catalytic
A0W34_RS18665	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
A0W34_RS18685	COG0183	Belongs to the thiolase family
A0W34_RS18705	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
A0W34_RS18735	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
A0W34_RS18750	COG0355	proton-transporting ATP synthase activity, rotational mechanism
A0W34_RS18755	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
A0W34_RS18760	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
A0W34_RS18765	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
A0W34_RS18770	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
A0W34_RS18775	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
A0W34_RS18780	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
A0W34_RS18785	COG0356	it plays a direct role in the translocation of protons across the membrane
A0W34_RS18795	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A0W34_RS18800	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
A0W34_RS18810	COG2890	protein-(glutamine-N5) methyltransferase activity
A0W34_RS18815	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
A0W34_RS18820	COG0254	rRNA binding
A0W34_RS18830	COG0083	homoserine kinase activity
A0W34_RS18835	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
A0W34_RS18840	COG0460	homoserine dehydrogenase
A0W34_RS18845	COG0019	diaminopimelate decarboxylase activity
A0W34_RS18850	COG0018	arginyl-trna synthetase
A0W34_RS18865	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
A0W34_RS18880	COG0477	Major facilitator Superfamily
A0W34_RS18900	COG0686	Belongs to the AlaDH PNT family
A0W34_RS18910	COG1218	3'(2'),5'-bisphosphate nucleotidase
A0W34_RS18945	COG0596	Alpha beta hydrolase
A0W34_RS18970	COG2814	Major facilitator Superfamily
A0W34_RS18995	COG1024	Enoyl-CoA hydratase
A0W34_RS19000	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS19015	COG0363	glucosamine-6-phosphate deaminase activity
A0W34_RS19020	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
A0W34_RS19025	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A0W34_RS19035	COG1263	PTS System
A0W34_RS19040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A0W34_RS19045	COG2190	(PTS) system
A0W34_RS19050	COG2188	Transcriptional regulator
A0W34_RS19055	COG4279	zinc finger
A0W34_RS19060	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A0W34_RS19065	COG3321	synthase
A0W34_RS19065	COG0604	alcohol dehydrogenase
A0W34_RS19090	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
A0W34_RS19105	COG1280	lysine exporter protein (LysE YggA)
A0W34_RS19115	COG3135	benzoate transporter
A0W34_RS19135	COG0022	dehydrogenase e1 component
A0W34_RS19140	COG0508	dehydrogenase complex catalyzes the overall conversion of
A0W34_RS19145	COG2223	nitrite transmembrane transporter activity
A0W34_RS19175	COG0318	PFAM AMP-dependent synthetase and ligase
A0W34_RS19210	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
A0W34_RS19210	COG0351	phosphomethylpyrimidine kinase
A0W34_RS19210	COG0352	thiamine-phosphate diphosphorylase activity
A0W34_RS19215	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A0W34_RS19220	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A0W34_RS19250	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
A0W34_RS19255	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A0W34_RS19260	COG1522	sequence-specific DNA binding
A0W34_RS19305	COG1063	alcohol dehydrogenase
A0W34_RS19315	COG1053	succinate dehydrogenase
A0W34_RS19315	COG3976	FMN-binding domain protein
A0W34_RS19330	COG1022	Amp-dependent synthetase and ligase
A0W34_RS19340	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A0W34_RS19355	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
A0W34_RS19355	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
A0W34_RS19390	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
A0W34_RS19400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A0W34_RS19405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A0W34_RS19415	COG0531	amino acid
A0W34_RS19420	COG3457	Alanine racemase
A0W34_RS19435	COG4172	Belongs to the ABC transporter superfamily
A0W34_RS19440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A0W34_RS19480	COG2310	stress, protein
A0W34_RS19485	COG1100	Small GTP-binding protein
A0W34_RS19535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A0W34_RS19540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A0W34_RS19545	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
A0W34_RS19550	COG1823	symporter activity
A0W34_RS19565	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A0W34_RS19615	COG0439	Biotin carboxylase
A0W34_RS19635	COG0667	Aldo Keto reductase
A0W34_RS19660	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS19670	COG0577	efflux transmembrane transporter activity
A0W34_RS19675	COG0577	efflux transmembrane transporter activity
A0W34_RS19675	COG1136	(ABC) transporter
A0W34_RS19685	COG3012	SEC-C Motif Domain Protein
A0W34_RS19695	COG1132	(ABC) transporter
A0W34_RS19705	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A0W34_RS19720	COG1022	Amp-dependent synthetase and ligase
A0W34_RS19730	COG0277	FAD linked oxidase domain protein
A0W34_RS19740	COG1335	isochorismatase
A0W34_RS19745	COG2267	carboxylic ester hydrolase activity
A0W34_RS19770	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
A0W34_RS19775	COG1024	Enoyl-CoA hydratase
A0W34_RS19780	COG0318	PFAM AMP-dependent synthetase and ligase
A0W34_RS19790	COG0277	FAD linked oxidase domain protein
A0W34_RS19810	COG0435	Glutathione S-transferase
A0W34_RS19825	COG1131	(ABC) transporter
A0W34_RS19835	COG1132	(ABC) transporter
A0W34_RS19840	COG0567	Dehydrogenase, E1 component
A0W34_RS19840	COG0508	dehydrogenase complex catalyzes the overall conversion of
A0W34_RS19845	COG1309	transcriptional regulator
A0W34_RS19875	COG1125	glycine betaine transport
A0W34_RS19875	COG0517	IMP dehydrogenase activity
A0W34_RS19880	COG1174	glycine betaine transport
A0W34_RS19900	COG2095	MarC family integral membrane protein
A0W34_RS19910	COG0598	Magnesium transport protein CorA
A0W34_RS19975	COG2301	Belongs to the HpcH HpaI aldolase family
A0W34_RS19980	COG2239	Acts as a magnesium transporter
A0W34_RS20010	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A0W34_RS20015	COG5662	AntiSigma factor
A0W34_RS20030	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
A0W34_RS20035	COG0297	glycogen (starch) synthase activity
A0W34_RS20040	COG2226	methyltransferase
A0W34_RS20050	COG0519	Catalyzes the synthesis of GMP from XMP
A0W34_RS20060	COG0463	Glycosyl transferase, family 2
A0W34_RS20065	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
A0W34_RS20070	COG0318	PFAM AMP-dependent synthetase and ligase
A0W34_RS20075	COG1611	Belongs to the LOG family
A0W34_RS20080	COG1611	Belongs to the LOG family
A0W34_RS20090	COG2171	N-acyltransferase activity
A0W34_RS20095	COG1113	amino acid transport
A0W34_RS20105	COG1131	(ABC) transporter
A0W34_RS20145	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
A0W34_RS20175	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A0W34_RS20180	COG0747	negative chemotaxis
A0W34_RS20195	COG2154	pterin-4-alpha-carbinolamine dehydratase
A0W34_RS20215	COG2814	Major facilitator Superfamily
A0W34_RS20225	COG3757	hydrolase, family 25
A0W34_RS20240	COG0402	S-adenosylhomocysteine deaminase activity
A0W34_RS20275	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
A0W34_RS20275	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
A0W34_RS20320	COG0584	glycerophosphoryl diester phosphodiesterase
A0W34_RS20330	COG0564	pseudouridine synthase activity
A0W34_RS20335	COG0012	GTP binding
A0W34_RS20345	COG0069	glutamate synthase activity
A0W34_RS20350	COG1966	Carbon starvation protein
A0W34_RS20370	COG0419	ATPase involved in DNA repair
A0W34_RS20375	COG0420	3'-5' exonuclease activity
A0W34_RS20385	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
A0W34_RS20395	COG1570	exodeoxyribonuclease VII activity
A0W34_RS20435	COG0477	Major facilitator Superfamily
A0W34_RS20445	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
A0W34_RS20455	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
A0W34_RS20460	COG2197	response regulator
A0W34_RS20470	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
A0W34_RS20480	COG1072	(Pantothenic acid kinase))
A0W34_RS20485	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
A0W34_RS20495	COG1331	Highly conserved protein containing a thioredoxin domain
A0W34_RS20505	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A0W34_RS20515	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A0W34_RS20520	COG3883	PFAM NLP P60 protein
A0W34_RS20520	COG0791	NLP P60 protein
A0W34_RS20535	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A0W34_RS20550	COG2755	lipolytic protein G-D-S-L family
A0W34_RS20555	COG0183	Belongs to the thiolase family
A0W34_RS20560	COG1024	Enoyl-CoA hydratase
A0W34_RS20570	COG2813	Specifically methylates the guanine in position
A0W34_RS20585	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS20595	COG5001	Diguanylate cyclase
A0W34_RS20640	COG0148	phosphopyruvate hydratase activity
A0W34_RS20650	COG0672	)-iron permease
A0W34_RS20660	COG2837	iron assimilation
A0W34_RS20725	COG3956	TIGRFAM MazG family protein
A0W34_RS20745	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
A0W34_RS20755	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A0W34_RS20760	COG0736	holo-[acyl-carrier-protein] synthase activity
A0W34_RS20770	COG1309	transcriptional regulator
A0W34_RS20780	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
A0W34_RS20795	COG0490	domain, Protein
A0W34_RS20795	COG0471	metal ion transport
A0W34_RS20805	COG2133	pyrroloquinoline quinone binding
A0W34_RS20820	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
A0W34_RS20830	COG1262	PFAM Formylglycine-generating sulfatase enzyme
A0W34_RS20835	COG3572	ergothioneine biosynthetic process
A0W34_RS20850	COG1053	succinate dehydrogenase
A0W34_RS20850	COG3976	FMN-binding domain protein
A0W34_RS20860	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
A0W34_RS20865	COG0193	aminoacyl-tRNA hydrolase activity
A0W34_RS20870	COG0318	PFAM AMP-dependent synthetase and ligase
A0W34_RS20875	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
A0W34_RS20920	COG2814	Major facilitator Superfamily
A0W34_RS20940	COG1120	ATPase activity
A0W34_RS20945	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A0W34_RS20950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A0W34_RS20970	COG2207	Transcriptional regulator
A0W34_RS20990	COG0488	(ABC) transporter
A0W34_RS20995	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
A0W34_RS21035	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
A0W34_RS21040	COG3583	domain protein
A0W34_RS21045	COG3583	domain protein
A0W34_RS21050	COG0765	amino acid transport
A0W34_RS21055	COG1126	abc transporter atp-binding protein
A0W34_RS21065	COG0084	hydrolase, TatD family'
A0W34_RS21090	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A0W34_RS21095	COG2259	Doxx family
A0W34_RS21110	COG1393	Belongs to the ArsC family
A0W34_RS21115	COG2235	arginine
A0W34_RS21120	COG4044	May play a role in the intracellular transport of hydrophobic ligands
A0W34_RS21180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A0W34_RS21190	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A0W34_RS21195	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
A0W34_RS21210	COG1970	mechanosensitive ion channel activity
A0W34_RS21215	COG0315	cyclic pyranopterin monophosphate synthase activity
A0W34_RS21215	COG0521	Mo-molybdopterin cofactor biosynthetic process
A0W34_RS21220	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A0W34_RS21235	COG2860	membrane
A0W34_RS21245	COG0254	rRNA binding
A0W34_RS21255	COG0227	Belongs to the bacterial ribosomal protein bL28 family
A0W34_RS21265	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
A0W34_RS21270	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
A0W34_RS21315	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A0W34_RS21320	COG2957	Belongs to the agmatine deiminase family
A0W34_RS21330	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
A0W34_RS21375	COG1739	Uncharacterized protein family UPF0029
A0W34_RS21385	COG0045	succinate-CoA ligase (ADP-forming) activity
A0W34_RS21395	COG0739	heme binding
A0W34_RS21435	COG1131	(ABC) transporter
A0W34_RS21450	COG1252	NADH dehydrogenase
A0W34_RS21460	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A0W34_RS21465	COG2272	Belongs to the type-B carboxylesterase lipase family
A0W34_RS21470	COG2272	Belongs to the type-B carboxylesterase lipase family
A0W34_RS21480	COG1396	sequence-specific DNA binding
A0W34_RS21490	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A0W34_RS21515	COG2814	Major facilitator Superfamily
A0W34_RS21520	COG0583	DNA-binding transcription factor activity
A0W34_RS21525	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
A0W34_RS21530	COG3706	GGDEF domain
A0W34_RS21545	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
A0W34_RS21580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A0W34_RS21600	COG1113	amino acid transport
A0W34_RS21610	COG1070	Carbohydrate kinase
A0W34_RS21625	COG1940	carbohydrate kinase activity
A0W34_RS21625	COG1846	Transcriptional regulator
A0W34_RS21630	COG0477	Major facilitator Superfamily
A0W34_RS21635	COG1024	Enoyl-CoA hydratase
A0W34_RS21650	COG0318	PFAM AMP-dependent synthetase and ligase
A0W34_RS21710	COG0183	Belongs to the thiolase family
A0W34_RS21715	COG0183	Belongs to the thiolase family
A0W34_RS21720	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS21750	COG1262	PFAM Formylglycine-generating sulfatase enzyme
A0W34_RS21755	COG2175	clavaminate synthase activity
A0W34_RS21765	COG3119	arylsulfatase activity
A0W34_RS21775	COG0642	Histidine kinase
A0W34_RS21775	COG3850	Histidine kinase
A0W34_RS21810	COG0477	Major facilitator Superfamily
A0W34_RS21840	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A0W34_RS21850	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A0W34_RS21860	COG3279	Response regulator of the LytR AlgR family
A0W34_RS21865	COG3275	phosphorelay sensor kinase activity
A0W34_RS21880	COG0025	NhaP-type Na H and K H
A0W34_RS21895	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
A0W34_RS21910	COG2072	flavoprotein involved in K transport
A0W34_RS21915	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A0W34_RS21930	COG2018	Roadblock/LC7 domain
A0W34_RS21965	COG3634	alkyl hydroperoxide reductase activity
A0W34_RS21975	COG1846	Transcriptional regulator
A0W34_RS21980	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A0W34_RS21990	COG0656	L-ascorbic acid biosynthetic process
A0W34_RS22000	COG0488	(ABC) transporter
A0W34_RS22005	COG0656	L-ascorbic acid biosynthetic process
A0W34_RS22015	COG0346	lactoylglutathione lyase activity
A0W34_RS22035	COG4152	abc transporter atp-binding protein
A0W34_RS22040	COG1668	transmembrane transport
A0W34_RS22085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A0W34_RS22095	COG2814	Major facilitator Superfamily
A0W34_RS22110	COG0415	Belongs to the DNA photolyase family
A0W34_RS22145	COG0659	secondary active sulfate transmembrane transporter activity
A0W34_RS22150	COG0667	Aldo Keto reductase
A0W34_RS22180	COG3284	Transcriptional regulator
A0W34_RS22185	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A0W34_RS22190	COG0508	dehydrogenase complex catalyzes the overall conversion of
A0W34_RS22195	COG0022	dehydrogenase e1 component
A0W34_RS22200	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A0W34_RS22225	COG0745	RESPONSE REGULATOR receiver
A0W34_RS22230	COG2205	protein histidine kinase activity
A0W34_RS22235	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
A0W34_RS22240	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
A0W34_RS22270	COG0545	Peptidyl-prolyl cis-trans isomerase
A0W34_RS22280	COG2017	converts alpha-aldose to the beta-anomer
A0W34_RS22290	COG0259	pyridoxamine-phosphate oxidase activity
A0W34_RS22300	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
A0W34_RS22320	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A0W34_RS22345	COG2252	PERMEase
A0W34_RS22380	COG2814	Major facilitator Superfamily
A0W34_RS22390	COG1278	Cold shock
A0W34_RS22445	COG1063	alcohol dehydrogenase
A0W34_RS22450	COG1061	Type III restriction enzyme res subunit
A0W34_RS22465	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A0W34_RS22475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A0W34_RS22495	COG1595	DNA-templated transcription, initiation
A0W34_RS22500	COG1289	transmembrane transporter activity
A0W34_RS22510	COG1309	transcriptional regulator
A0W34_RS22520	COG2072	flavoprotein involved in K transport
A0W34_RS22545	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS22670	COG1522	sequence-specific DNA binding
A0W34_RS22675	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
A0W34_RS22685	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
A0W34_RS22725	COG0318	PFAM AMP-dependent synthetase and ligase
A0W34_RS22730	COG1024	Enoyl-CoA hydratase
A0W34_RS22740	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS22745	COG0583	DNA-binding transcription factor activity
A0W34_RS22750	COG0477	Major facilitator Superfamily
A0W34_RS22755	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
A0W34_RS22770	COG0673	inositol 2-dehydrogenase activity
A0W34_RS22785	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
A0W34_RS22805	COG4335	DNA alkylation repair
A0W34_RS22820	COG1012	belongs to the aldehyde dehydrogenase family
A0W34_RS22825	COG0506	proline dehydrogenase activity
A0W34_RS22830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A0W34_RS22845	COG1131	(ABC) transporter
A0W34_RS22855	COG4585	Histidine kinase
A0W34_RS22860	COG2197	response regulator
A0W34_RS22875	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
A0W34_RS22885	COG1309	transcriptional regulator
A0W34_RS22915	COG0542	response to heat
A0W34_RS22925	COG2814	Major facilitator Superfamily
A0W34_RS22930	COG2084	Dehydrogenase
A0W34_RS22950	COG1574	metal-dependent hydrolase with the TIM-barrel fold
A0W34_RS22970	COG2197	response regulator
A0W34_RS23015	COG1846	Transcriptional regulator
A0W34_RS23020	COG1764	response to oxidative stress
A0W34_RS23025	COG2130	NADP-dependent
A0W34_RS23065	COG1953	Uracil, thiamine, allantoin
A0W34_RS23075	COG2814	Major facilitator Superfamily
A0W34_RS23080	COG0640	Transcriptional regulator
A0W34_RS23100	COG2072	flavoprotein involved in K transport
A0W34_RS23120	COG4266	Belongs to the allantoicase family
A0W34_RS23135	COG0564	pseudouridine synthase activity
A0W34_RS23145	COG0589	response to stress
A0W34_RS23155	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS23160	COG1309	transcriptional regulator
A0W34_RS23170	COG0477	Major facilitator Superfamily
A0W34_RS23175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A0W34_RS23180	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A0W34_RS23215	COG0477	Major facilitator Superfamily
A0W34_RS23235	COG1309	transcriptional regulator
A0W34_RS23275	COG2814	Major facilitator Superfamily
A0W34_RS23280	COG0583	DNA-binding transcription factor activity
A0W34_RS23310	COG0829	nickel cation binding
A0W34_RS23315	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
A0W34_RS23325	COG0804	urea catabolic process
A0W34_RS23330	COG0832	Belongs to the urease beta subunit family
A0W34_RS23335	COG0831	urea catabolic process
A0W34_RS23340	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A0W34_RS23345	COG0581	inorganic phosphate transmembrane transporter activity
A0W34_RS23360	COG0454	-acetyltransferase
A0W34_RS23360	COG0456	acetyltransferase
A0W34_RS23365	COG0745	RESPONSE REGULATOR receiver
A0W34_RS23385	COG2897	thiosulfate sulfurtransferase activity
A0W34_RS23395	COG4044	May play a role in the intracellular transport of hydrophobic ligands
A0W34_RS23405	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
A0W34_RS23410	COG4988	ABC transporter
A0W34_RS23415	COG1294	oxidase, subunit
A0W34_RS23420	COG1271	oxidase subunit
A0W34_RS23450	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
A0W34_RS23490	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A0W34_RS23495	COG2837	iron assimilation
A0W34_RS23500	COG1362	aminopeptidase activity
A0W34_RS23515	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS23520	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
A0W34_RS23525	COG0135	phosphoribosylanthranilate isomerase activity
A0W34_RS23535	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS23545	COG2267	carboxylic ester hydrolase activity
A0W34_RS23550	COG2130	NADP-dependent
A0W34_RS23560	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS23565	COG1609	Transcriptional regulator
A0W34_RS23580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A0W34_RS23585	COG0657	acetylesterase activity
A0W34_RS23600	COG2072	flavoprotein involved in K transport
A0W34_RS23635	COG4521	taurine ABC transporter
A0W34_RS23640	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A0W34_RS23670	COG2304	oxidoreductase activity
A0W34_RS23675	COG5002	protein histidine kinase activity
A0W34_RS23675	COG5001	Diguanylate cyclase
A0W34_RS23675	COG3447	MASE1 domain protein
A0W34_RS23685	COG1846	Transcriptional regulator
A0W34_RS23715	COG2072	flavoprotein involved in K transport
A0W34_RS23745	COG1983	PspC domain protein
A0W34_RS23765	COG1733	regulation of RNA biosynthetic process
A0W34_RS23770	COG0778	Nitroreductase
A0W34_RS23775	COG1174	glycine betaine transport
A0W34_RS23785	COG1174	glycine betaine transport
A0W34_RS23795	COG4106	trans-aconitate 2-methyltransferase activity
A0W34_RS23805	COG0318	PFAM AMP-dependent synthetase and ligase
A0W34_RS23810	COG1946	Acyl-CoA thioesterase
A0W34_RS23815	COG2814	Major facilitator Superfamily
A0W34_RS23820	COG0183	Belongs to the thiolase family
A0W34_RS23825	COG0318	PFAM AMP-dependent synthetase and ligase
A0W34_RS23835	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS23840	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A0W34_RS23845	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS23850	COG0183	Belongs to the thiolase family
A0W34_RS23865	COG0183	Belongs to the thiolase family
A0W34_RS23870	COG0318	PFAM AMP-dependent synthetase and ligase
A0W34_RS23875	COG1802	Transcriptional regulator
A0W34_RS23880	COG1024	Enoyl-CoA hydratase
A0W34_RS23890	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS23895	COG1309	transcriptional regulator
A0W34_RS23910	COG2175	clavaminate synthase activity
A0W34_RS23970	COG1574	metal-dependent hydrolase with the TIM-barrel fold
A0W34_RS23985	COG0488	(ABC) transporter
A0W34_RS24000	COG1053	succinate dehydrogenase
A0W34_RS24010	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS24050	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
A0W34_RS24065	COG3590	peptidase
A0W34_RS24070	COG1742	UPF0060 membrane protein
A0W34_RS24075	COG3842	ATPase activity
A0W34_RS24090	COG1175	transmembrane transport
A0W34_RS24095	COG1376	ErfK ybiS ycfS ynhG family protein
A0W34_RS24110	COG3360	Dodecin
A0W34_RS24115	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A0W34_RS24130	COG1793	dna ligase
A0W34_RS24140	COG0598	Magnesium transport protein CorA
A0W34_RS24150	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS24165	COG4166	transmembrane transport
A0W34_RS24175	COG0444	Belongs to the ABC transporter superfamily
A0W34_RS24200	COG4948	Mandelate Racemase Muconate Lactonizing
A0W34_RS24220	COG0318	PFAM AMP-dependent synthetase and ligase
A0W34_RS24255	COG1408	metallophosphoesterase
A0W34_RS24265	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A0W34_RS24275	COG0277	FAD linked oxidase domain protein
A0W34_RS24280	COG2318	DinB family
A0W34_RS24285	COG0326	Molecular chaperone. Has ATPase activity
A0W34_RS24290	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS24295	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS24315	COG1673	EVE domain
A0W34_RS24320	COG1309	transcriptional regulator
A0W34_RS24335	COG0300	oxidoreductase activity
A0W34_RS24340	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
A0W34_RS24350	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
A0W34_RS24355	COG2079	MmgE PrpD family protein
A0W34_RS24360	COG3800	Transcriptional regulator
A0W34_RS24360	COG1396	sequence-specific DNA binding
A0W34_RS24375	COG2015	COG2015, Alkyl sulfatase and related hydrolases
A0W34_RS24390	COG2271	Major facilitator Superfamily
A0W34_RS24395	COG0667	Aldo Keto reductase
A0W34_RS24420	COG0129	dihydroxy-acid dehydratase activity
A0W34_RS24435	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
A0W34_RS24445	COG0477	Major facilitator Superfamily
A0W34_RS24455	COG3185	4-Hydroxyphenylpyruvate dioxygenase
A0W34_RS24465	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
A0W34_RS24480	COG0583	DNA-binding transcription factor activity
A0W34_RS24490	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS24495	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS24505	COG2030	dehydratase
A0W34_RS24510	COG0183	Belongs to the thiolase family
A0W34_RS24520	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS24530	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS24550	COG2011	ABC-type metal ion transport system permease component
A0W34_RS24590	COG0318	PFAM AMP-dependent synthetase and ligase
A0W34_RS24595	COG0318	PFAM AMP-dependent synthetase and ligase
A0W34_RS24605	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A0W34_RS24610	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
A0W34_RS24630	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS24640	COG2030	dehydratase
A0W34_RS24645	COG0183	Belongs to the thiolase family
A0W34_RS24650	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS24655	COG0183	Belongs to the thiolase family
A0W34_RS24660	COG1309	transcriptional regulator
A0W34_RS24690	COG0640	Transcriptional regulator
A0W34_RS24695	COG0174	glutamine synthetase
A0W34_RS24700	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS24725	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS24760	COG2902	Dehydrogenase
A0W34_RS24765	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS24785	COG2986	histidine ammonia-lyase
A0W34_RS24790	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A0W34_RS24795	COG0277	FAD linked oxidase domain protein
A0W34_RS24800	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
A0W34_RS24805	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
A0W34_RS24810	COG1228	amidohydrolase
A0W34_RS24830	COG1309	transcriptional regulator
A0W34_RS24845	COG2175	clavaminate synthase activity
A0W34_RS24850	COG0789	Transcriptional regulator
A0W34_RS24860	COG0318	PFAM AMP-dependent synthetase and ligase
A0W34_RS24875	COG1309	transcriptional regulator
A0W34_RS24880	COG1309	transcriptional regulator
A0W34_RS24920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A0W34_RS24935	COG0318	PFAM AMP-dependent synthetase and ligase
A0W34_RS24940	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS24965	COG0604	alcohol dehydrogenase
A0W34_RS24990	COG0640	Transcriptional regulator
A0W34_RS24995	COG0183	Belongs to the thiolase family
A0W34_RS25005	COG2188	Transcriptional regulator
A0W34_RS25015	COG2301	Belongs to the HpcH HpaI aldolase family
A0W34_RS25025	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A0W34_RS25030	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS25040	COG2271	Major facilitator Superfamily
A0W34_RS25045	COG0183	Belongs to the thiolase family
A0W34_RS25055	COG0318	PFAM AMP-dependent synthetase and ligase
A0W34_RS25065	COG0583	DNA-binding transcription factor activity
A0W34_RS25070	COG0583	DNA-binding transcription factor activity
A0W34_RS25075	COG1024	Enoyl-CoA hydratase
A0W34_RS25080	COG1024	Enoyl-CoA hydratase
A0W34_RS25085	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A0W34_RS25090	COG0318	PFAM AMP-dependent synthetase and ligase
A0W34_RS25095	COG0583	DNA-binding transcription factor activity
A0W34_RS25100	COG0583	DNA-binding transcription factor activity
A0W34_RS25110	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS25115	COG0183	Belongs to the thiolase family
A0W34_RS25120	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A0W34_RS25130	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS25135	COG0318	PFAM AMP-dependent synthetase and ligase
A0W34_RS25140	COG1024	Enoyl-CoA hydratase
A0W34_RS25145	COG1012	belongs to the aldehyde dehydrogenase family
A0W34_RS25150	COG0653	protein targeting
A0W34_RS25155	COG0653	protein targeting
A0W34_RS25165	COG0028	Belongs to the TPP enzyme family
A0W34_RS25200	COG1012	belongs to the aldehyde dehydrogenase family
A0W34_RS25220	COG1846	Transcriptional regulator
A0W34_RS25230	COG1984	allophanate hydrolase subunit 2
A0W34_RS25240	COG2409	Drug exporters of the RND superfamily
A0W34_RS25250	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A0W34_RS25255	COG1595	DNA-templated transcription, initiation
A0W34_RS25260	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A0W34_RS25270	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS25280	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS25285	COG1132	(ABC) transporter
A0W34_RS25290	COG1309	transcriptional regulator
A0W34_RS25325	COG2365	Tyrosine phosphatase family
A0W34_RS25335	COG1309	transcriptional regulator
A0W34_RS25355	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS25360	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS25375	COG4941	Belongs to the sigma-70 factor family
A0W34_RS25380	COG3795	YCII-related domain
A0W34_RS25395	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS25400	COG1556	Lactate utilization protein
A0W34_RS25405	COG1139	Iron-sulfur cluster binding protein
A0W34_RS25410	COG0247	lactate metabolic process
A0W34_RS25415	COG1802	Transcriptional regulator
A0W34_RS25440	COG1172	Belongs to the binding-protein-dependent transport system permease family
A0W34_RS25465	COG1609	Transcriptional regulator
A0W34_RS25470	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A0W34_RS25490	COG3708	Transcriptional regulator
A0W34_RS25490	COG2207	Transcriptional regulator
A0W34_RS25505	COG3485	protocatechuate 3,4-dioxygenase
A0W34_RS25510	COG3485	protocatechuate 3,4-dioxygenase
A0W34_RS25515	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A0W34_RS25520	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A0W34_RS25525	COG1414	Transcriptional regulator
A0W34_RS25555	COG1278	Cold shock
A0W34_RS25580	COG0668	transmembrane transport
A0W34_RS25585	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
A0W34_RS25590	COG0590	tRNA wobble adenosine to inosine editing
A0W34_RS25615	COG2267	carboxylic ester hydrolase activity
A0W34_RS25625	COG1305	Transglutaminase-like
A0W34_RS25630	COG0657	acetylesterase activity
A0W34_RS25640	COG3265	gluconokinase activity
A0W34_RS25650	COG2186	Transcriptional regulator
A0W34_RS25655	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
A0W34_RS25660	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS25725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A0W34_RS25745	COG3119	arylsulfatase activity
A0W34_RS25755	COG0531	amino acid
A0W34_RS25765	COG2267	carboxylic ester hydrolase activity
A0W34_RS25785	COG1725	Transcriptional regulator
A0W34_RS25795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A0W34_RS25800	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
A0W34_RS25805	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
A0W34_RS25825	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A0W34_RS25840	COG2132	Multicopper oxidase
A0W34_RS25865	COG1132	(ABC) transporter
A0W34_RS25880	COG2132	Multicopper oxidase
A0W34_RS25930	COG3467	pyridoxamine 5'-phosphate
A0W34_RS25965	COG1959	2 iron, 2 sulfur cluster binding
A0W34_RS25980	COG1063	alcohol dehydrogenase
A0W34_RS26000	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
A0W34_RS26050	COG2807	transmembrane transport
A0W34_RS26055	COG3145	DNA-N1-methyladenine dioxygenase activity
A0W34_RS26060	COG0640	Transcriptional regulator
A0W34_RS26090	COG0477	Major facilitator Superfamily
A0W34_RS26105	COG3835	regulator
A0W34_RS26130	COG2197	response regulator
A0W34_RS26150	COG4829	muconolactone delta-isomerase
A0W34_RS26155	COG4948	Mandelate Racemase Muconate Lactonizing
A0W34_RS26160	COG3485	protocatechuate 3,4-dioxygenase
A0W34_RS26165	COG1414	Transcriptional regulator
A0W34_RS26185	COG4638	Rieske (2fe-2S)
A0W34_RS26190	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
A0W34_RS26205	COG2814	Major facilitator Superfamily
A0W34_RS26245	COG2223	nitrite transmembrane transporter activity
A0W34_RS26250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A0W34_RS26260	COG1309	transcriptional regulator
A0W34_RS26275	COG0604	alcohol dehydrogenase
A0W34_RS26305	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS26310	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A0W34_RS26340	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A0W34_RS26360	COG0412	Dienelactone hydrolase
A0W34_RS26365	COG0833	amino acid
A0W34_RS26375	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
A0W34_RS26380	COG1522	sequence-specific DNA binding
A0W34_RS26410	COG0519	Catalyzes the synthesis of GMP from XMP
A0W34_RS26410	COG0518	GMP synthase (glutamine-hydrolyzing) activity
A0W34_RS26430	COG0640	Transcriptional regulator
A0W34_RS26455	COG0183	Belongs to the thiolase family
A0W34_RS26465	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS26470	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS26485	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS26495	COG1024	Enoyl-CoA hydratase
A0W34_RS26500	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS26515	COG0318	PFAM AMP-dependent synthetase and ligase
A0W34_RS26540	COG0318	PFAM AMP-dependent synthetase and ligase
A0W34_RS26555	COG1802	Transcriptional regulator
A0W34_RS26560	COG1119	ATPase activity
A0W34_RS26580	COG3300	MHYT domain
A0W34_RS26580	COG5001	Diguanylate cyclase
A0W34_RS26585	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A0W34_RS26600	COG1802	Transcriptional regulator
A0W34_RS26675	COG3835	regulator
A0W34_RS26685	COG2814	Major facilitator Superfamily
A0W34_RS26705	COG1053	succinate dehydrogenase
A0W34_RS26715	COG0471	metal ion transport
A0W34_RS26750	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
A0W34_RS26755	COG1959	2 iron, 2 sulfur cluster binding
A0W34_RS26760	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A0W34_RS26760	COG1017	nitric oxide dioxygenase activity
A0W34_RS26775	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A0W34_RS26780	COG2151	metal-sulfur cluster biosynthetic enzyme
A0W34_RS26785	COG3396	Phenylacetate-CoA oxygenase
A0W34_RS26790	COG3460	Phenylacetate-CoA oxygenase
A0W34_RS26795	COG3396	Phenylacetate-CoA oxygenase
A0W34_RS26800	COG1024	Enoyl-CoA hydratase
A0W34_RS26805	COG1250	3-hydroxyacyl-CoA dehydrogenase
A0W34_RS26810	COG1024	Enoyl-CoA hydratase
A0W34_RS26820	COG2030	dehydratase
A0W34_RS26820	COG1012	belongs to the aldehyde dehydrogenase family
A0W34_RS26830	COG2050	protein possibly involved in aromatic compounds catabolism
A0W34_RS26830	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
A0W34_RS26835	COG3458	cephalosporin-C deacetylase activity
A0W34_RS26860	COG0596	Alpha beta hydrolase
A0W34_RS26870	COG1012	belongs to the aldehyde dehydrogenase family
A0W34_RS26880	COG1113	amino acid transport
A0W34_RS26885	COG2199	diguanylate cyclase activity
A0W34_RS26890	COG5001	Diguanylate cyclase
A0W34_RS26895	COG0477	Major facilitator Superfamily
A0W34_RS26900	COG3552	Protein containing von Willebrand factor type A (VWA) domain
A0W34_RS26910	COG0714	Associated with various cellular activities
A0W34_RS26945	COG0318	PFAM AMP-dependent synthetase and ligase
A0W34_RS26980	COG1252	NADH dehydrogenase
A0W34_RS26985	COG0583	DNA-binding transcription factor activity
A0W34_RS26995	COG0477	Major facilitator Superfamily
A0W34_RS27005	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS27020	COG0657	acetylesterase activity
A0W34_RS27035	COG2124	cytochrome p450
A0W34_RS27040	COG2130	NADP-dependent
A0W34_RS27060	COG4221	oxidoreductase activity
A0W34_RS27075	COG0318	PFAM AMP-dependent synthetase and ligase
A0W34_RS27080	COG1024	Enoyl-CoA hydratase
A0W34_RS27090	COG1072	(Pantothenic acid kinase))
A0W34_RS27115	COG1609	Transcriptional regulator
A0W34_RS27130	COG0477	Major facilitator Superfamily
A0W34_RS27145	COG2186	Transcriptional regulator
A0W34_RS27150	COG2226	methyltransferase
A0W34_RS27155	COG1607	acyl-coa hydrolase
A0W34_RS27200	COG2376	Dihydroxyacetone kinase
A0W34_RS27220	COG0183	Belongs to the thiolase family
A0W34_RS27225	COG0515	serine threonine protein kinase
A0W34_RS27240	COG4221	oxidoreductase activity
A0W34_RS27260	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A0W34_RS27270	COG4977	sequence-specific DNA binding
A0W34_RS27270	COG1917	Cupin 2, conserved barrel domain protein
A0W34_RS27280	COG2186	Transcriptional regulator
A0W34_RS27300	COG2909	trisaccharide binding
A0W34_RS27415	COG2267	carboxylic ester hydrolase activity
A0W34_RS27430	COG1309	transcriptional regulator
A0W34_RS27435	COG1250	3-hydroxyacyl-CoA dehydrogenase
A0W34_RS27445	COG0070	glutamate synthase
A0W34_RS27445	COG0069	glutamate synthase activity
A0W34_RS27445	COG0067	glutamate synthase
A0W34_RS27450	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
A0W34_RS27460	COG1132	(ABC) transporter
A0W34_RS27485	COG2375	cellular response to nickel ion
A0W34_RS27490	COG2207	Transcriptional regulator
A0W34_RS27495	COG2957	Belongs to the agmatine deiminase family
A0W34_RS27525	COG0318	PFAM AMP-dependent synthetase and ligase
A0W34_RS27535	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS27555	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
A0W34_RS27570	COG3511	phospholipase C
A0W34_RS27580	COG0657	acetylesterase activity
A0W34_RS27585	COG1733	regulation of RNA biosynthetic process
A0W34_RS27615	COG2146	nitrite reductase [NAD(P)H] activity
A0W34_RS27615	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
A0W34_RS27630	COG0596	Alpha beta hydrolase
A0W34_RS27635	COG3903	Transcriptional regulator
A0W34_RS27635	COG3629	intracellular signal transduction
A0W34_RS27640	COG2272	Belongs to the type-B carboxylesterase lipase family
A0W34_RS27655	COG0745	RESPONSE REGULATOR receiver
A0W34_RS27675	COG1597	lipid kinase activity
A0W34_RS27690	COG1309	transcriptional regulator
A0W34_RS27705	COG1309	transcriptional regulator
A0W34_RS27740	COG4941	Belongs to the sigma-70 factor family
A0W34_RS27775	COG0406	alpha-ribazole phosphatase activity
A0W34_RS27785	COG1012	belongs to the aldehyde dehydrogenase family
A0W34_RS27810	COG1120	ATPase activity
A0W34_RS27815	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A0W34_RS27820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A0W34_RS27825	COG4592	Periplasmic binding protein
A0W34_RS27855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A0W34_RS27885	COG1546	Belongs to the CinA family
A0W34_RS27885	COG1058	Belongs to the CinA family
A0W34_RS27920	COG3973	AAA domain
A0W34_RS27930	COG3971	2-oxopent-4-enoate hydratase activity
A0W34_RS27935	COG4569	acetaldehyde dehydrogenase (acetylating) activity
A0W34_RS27940	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A0W34_RS27960	COG2318	DinB family
A0W34_RS27980	COG0789	Transcriptional regulator
A0W34_RS28025	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS28040	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS28055	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS28065	COG2133	pyrroloquinoline quinone binding
A0W34_RS28085	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS28100	COG0477	Major facilitator Superfamily
A0W34_RS28105	COG0583	DNA-binding transcription factor activity
A0W34_RS28125	COG2226	methyltransferase
A0W34_RS28145	COG1846	Transcriptional regulator
A0W34_RS28155	COG3552	Protein containing von Willebrand factor type A (VWA) domain
A0W34_RS28160	COG2425	protein containing a von Willebrand factor type A (vWA) domain
A0W34_RS28165	COG0714	Associated with various cellular activities
A0W34_RS28180	COG0154	amidase activity
A0W34_RS28205	COG0583	DNA-binding transcription factor activity
A0W34_RS28215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A0W34_RS28235	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A0W34_RS28260	COG1902	pentaerythritol trinitrate reductase activity
A0W34_RS28260	COG0446	pyridine nucleotide-disulphide oxidoreductase
A0W34_RS28270	COG1012	belongs to the aldehyde dehydrogenase family
A0W34_RS28275	COG0604	alcohol dehydrogenase
A0W34_RS28275	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS28275	COG3321	synthase
A0W34_RS28300	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
A0W34_RS28305	COG1535	isochorismatase
A0W34_RS28305	COG3433	isochorismatase activity
A0W34_RS28315	COG1609	Transcriptional regulator
A0W34_RS28325	COG0443	Heat shock 70 kDa protein
A0W34_RS28330	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
A0W34_RS28345	COG0542	response to heat
A0W34_RS28360	COG0492	ferredoxin-NADP+ reductase activity
A0W34_RS28385	COG0359	binds to the 23S rRNA
A0W34_RS28390	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
A0W34_RS28400	COG0360	Binds together with S18 to 16S ribosomal RNA
A0W34_RS28420	COG4249	Peptidase C14 caspase catalytic subunit p20
A0W34_RS28420	COG2319	Wd-40 repeat
A0W34_RS28435	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A0W34_RS28470	COG1260	myo-inositol-1-phosphate synthase
A0W34_RS28485	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A0W34_RS28500	COG0330	HflC and HflK could
A0W34_RS28510	COG1414	Transcriptional regulator
A0W34_RS28520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A0W34_RS28525	COG1116	anion transmembrane transporter activity
A0W34_RS28535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A0W34_RS28540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A0W34_RS28550	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A0W34_RS28560	COG0251	oxidation-reduction process
A0W34_RS28565	COG2267	carboxylic ester hydrolase activity
A0W34_RS28575	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A0W34_RS28580	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A0W34_RS28585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A0W34_RS28590	COG1116	anion transmembrane transporter activity
A0W34_RS28590	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A0W34_RS28605	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
A0W34_RS28635	COG2233	PERMEase
A0W34_RS28655	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
A0W34_RS28660	COG2508	Transcriptional regulator
A0W34_RS28675	COG2233	PERMEase
A0W34_RS28685	COG3608	succinylglutamate desuccinylase aspartoacylase
A0W34_RS28685	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
A0W34_RS28715	COG0154	amidase activity
A0W34_RS28735	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A0W34_RS28760	COG3842	ATPase activity
A0W34_RS28780	COG0740	serine-type endopeptidase activity
A0W34_RS28785	COG0740	serine-type endopeptidase activity
A0W34_RS28795	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A0W34_RS28800	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS28805	COG0477	Major facilitator Superfamily
A0W34_RS28810	COG0583	DNA-binding transcription factor activity
A0W34_RS28815	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS28825	COG1309	transcriptional regulator
A0W34_RS28870	COG0765	amino acid transport
A0W34_RS28875	COG1126	abc transporter atp-binding protein
A0W34_RS28880	COG4941	Belongs to the sigma-70 factor family
A0W34_RS28885	COG3795	YCII-related domain
A0W34_RS28890	COG2197	response regulator
A0W34_RS28905	COG1131	(ABC) transporter
A0W34_RS28930	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
A0W34_RS28950	COG1796	DNA polymerase
A0W34_RS28950	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
A0W34_RS28970	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A0W34_RS28975	COG1121	(ABC) transporter
A0W34_RS29005	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A0W34_RS29010	COG0508	dehydrogenase complex catalyzes the overall conversion of
A0W34_RS29025	COG1522	sequence-specific DNA binding
A0W34_RS29030	COG3220	belongs to the UPF0276 family
A0W34_RS29045	COG2837	iron assimilation
A0W34_RS29055	COG2267	carboxylic ester hydrolase activity
A0W34_RS29060	COG3631	Ketosteroid isomerase-related protein
A0W34_RS29080	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
A0W34_RS29085	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS29105	COG0477	Major facilitator Superfamily
A0W34_RS29115	COG0495	leucyl-tRNA aminoacylation
A0W34_RS29130	COG2186	Transcriptional regulator
A0W34_RS29135	COG2814	Major facilitator Superfamily
A0W34_RS29150	COG1678	Uncharacterized ACR, COG1678
A0W34_RS29170	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS29180	COG0617	tRNA 3'-terminal CCA addition
A0W34_RS29200	COG1595	DNA-templated transcription, initiation
A0W34_RS29230	COG3409	Peptidoglycan-binding domain 1 protein
A0W34_RS29230	COG0860	N-Acetylmuramoyl-L-alanine amidase
A0W34_RS29245	COG1192	Involved in chromosome partitioning
A0W34_RS29250	COG0357	Ribosomal RNA small subunit methyltransferase G
A0W34_RS29275	COG0706	membrane insertase activity
A0W34_RS29280	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
A0W34_RS29285	COG0594	ribonuclease P activity
A0W34_RS29290	COG0230	Belongs to the bacterial ribosomal protein bL34 family
A0W34_RS29325	COG0598	Magnesium transport protein CorA
A0W34_RS29350	COG0477	Major facilitator Superfamily
A0W34_RS29360	COG0633	Ferredoxin
A0W34_RS29385	COG1012	belongs to the aldehyde dehydrogenase family
A0W34_RS29390	COG4221	oxidoreductase activity
A0W34_RS29400	COG0318	PFAM AMP-dependent synthetase and ligase
A0W34_RS29410	COG2124	cytochrome p450
A0W34_RS29425	COG2963	transposase activity
A0W34_RS29430	COG2801	Transposase and inactivated derivatives
A0W34_RS29435	COG2826	transposase and inactivated derivatives, IS30 family
A0W34_RS29440	COG2801	Transposase and inactivated derivatives
A0W34_RS29450	COG0450	alkyl hydroperoxide reductase
A0W34_RS29495	COG1595	DNA-templated transcription, initiation
A0W34_RS29505	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A0W34_RS29525	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A0W34_RS29530	COG0446	pyridine nucleotide-disulphide oxidoreductase
A0W34_RS29540	COG1937	Protein conserved in bacteria
A0W34_RS29545	COG2409	Drug exporters of the RND superfamily
A0W34_RS29560	COG2226	methyltransferase
A0W34_RS29570	COG0477	Major facilitator Superfamily
A0W34_RS29585	COG4221	oxidoreductase activity
A0W34_RS29655	COG0492	ferredoxin-NADP+ reductase activity
A0W34_RS29660	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
A0W34_RS29665	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A0W34_RS29720	COG1012	belongs to the aldehyde dehydrogenase family
A0W34_RS29730	COG0318	PFAM AMP-dependent synthetase and ligase
A0W34_RS29740	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A0W34_RS29765	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
A0W34_RS29805	COG2015	COG2015, Alkyl sulfatase and related hydrolases
A0W34_RS29815	COG0183	Belongs to the thiolase family
A0W34_RS29830	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
A0W34_RS29835	COG0659	secondary active sulfate transmembrane transporter activity
A0W34_RS29845	COG0183	Belongs to the thiolase family
A0W34_RS29850	COG2824	Alkylphosphonate utilization operon protein PhnA
A0W34_RS29860	COG0183	Belongs to the thiolase family
A0W34_RS29900	COG0145	ligase activity
A0W34_RS29910	COG0145	ligase activity
A0W34_RS29975	COG3864	Putative metallopeptidase domain
A0W34_RS30000	COG2135	peptidase activity
A0W34_RS30015	COG4974	Belongs to the 'phage' integrase family
A0W34_RS30050	COG2130	NADP-dependent
A0W34_RS30060	COG0318	PFAM AMP-dependent synthetase and ligase
A0W34_RS30075	COG0183	Belongs to the thiolase family
A0W34_RS30100	COG1024	Enoyl-CoA hydratase
A0W34_RS30110	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
A0W34_RS30130	COG1309	transcriptional regulator
A0W34_RS30135	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS30140	COG2368	4-hydroxyphenylacetate
A0W34_RS30145	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS30155	COG1024	Enoyl-CoA hydratase
A0W34_RS30170	COG0183	Belongs to the thiolase family
A0W34_RS30180	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS30200	COG1024	Enoyl-CoA hydratase
A0W34_RS30220	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS30225	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS30240	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A0W34_RS30260	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS30270	COG1024	Enoyl-CoA hydratase
A0W34_RS30295	COG0318	PFAM AMP-dependent synthetase and ligase
A0W34_RS30305	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A0W34_RS30315	COG0444	Belongs to the ABC transporter superfamily
A0W34_RS30320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A0W34_RS30325	COG0601	transmembrane transport
A0W34_RS30330	COG0747	negative chemotaxis
A0W34_RS30340	COG4172	Belongs to the ABC transporter superfamily
A0W34_RS30345	COG2070	2-Nitropropane dioxygenase
A0W34_RS30350	COG0318	PFAM AMP-dependent synthetase and ligase
A0W34_RS30355	COG0667	Aldo Keto reductase
A0W34_RS30360	COG1024	Enoyl-CoA hydratase
A0W34_RS30380	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS30385	COG1309	transcriptional regulator
A0W34_RS30415	COG1012	belongs to the aldehyde dehydrogenase family
A0W34_RS30420	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS30475	COG1024	Enoyl-CoA hydratase
A0W34_RS30490	COG0411	ABC transporter
A0W34_RS30500	COG1024	Enoyl-CoA hydratase
A0W34_RS30505	COG0183	Belongs to the thiolase family
A0W34_RS30510	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS30515	COG0318	PFAM AMP-dependent synthetase and ligase
A0W34_RS30520	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS30545	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS30550	COG1024	Enoyl-CoA hydratase
A0W34_RS30560	COG1012	belongs to the aldehyde dehydrogenase family
A0W34_RS30570	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS30600	COG2186	Transcriptional regulator
A0W34_RS30605	COG1024	Enoyl-CoA hydratase
A0W34_RS30610	COG0318	PFAM AMP-dependent synthetase and ligase
A0W34_RS30625	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS30630	COG1946	Acyl-CoA thioesterase
A0W34_RS30645	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A0W34_RS30650	COG0667	Aldo Keto reductase
A0W34_RS30660	COG1024	Enoyl-CoA hydratase
A0W34_RS30665	COG1024	Enoyl-CoA hydratase
A0W34_RS30670	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS30680	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
A0W34_RS30725	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS30735	COG0601	transmembrane transport
A0W34_RS30760	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A0W34_RS30780	COG2188	Transcriptional regulator
A0W34_RS30820	COG1024	Enoyl-CoA hydratase
A0W34_RS30850	COG2186	Transcriptional regulator
A0W34_RS30855	COG1902	pentaerythritol trinitrate reductase activity
A0W34_RS30865	COG2188	Transcriptional regulator
A0W34_RS30870	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A0W34_RS30880	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
A0W34_RS30980	COG0789	Transcriptional regulator
A0W34_RS31005	COG0693	protein deglycase activity
A0W34_RS31045	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
A0W34_RS31065	COG0745	RESPONSE REGULATOR receiver
A0W34_RS31070	COG5002	protein histidine kinase activity
A0W34_RS31080	COG2890	protein-(glutamine-N5) methyltransferase activity
A0W34_RS31090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A0W34_RS31170	COG2217	Heavy metal translocating P-type atpase
A0W34_RS31185	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
A0W34_RS31190	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A0W34_RS31200	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A0W34_RS31270	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A0W34_RS31270	COG0574	Belongs to the PEP-utilizing enzyme family
A0W34_RS31275	COG0617	tRNA 3'-terminal CCA addition
A0W34_RS31275	COG0517	IMP dehydrogenase activity
A0W34_RS31275	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
A0W34_RS31305	COG3609	addiction module antidote protein, CC2985 family
A0W34_RS31310	COG2337	Toxic component of a toxin-antitoxin (TA) module
A0W34_RS31365	COG1595	DNA-templated transcription, initiation
A0W34_RS31550	COG2130	NADP-dependent
A0W34_RS31560	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS31570	COG1053	succinate dehydrogenase
A0W34_RS31625	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS31630	COG1028	Short-chain dehydrogenase reductase Sdr
A0W34_RS31635	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS31645	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS31660	COG1024	Enoyl-CoA hydratase
A0W34_RS31665	COG1960	acyl-CoA dehydrogenase activity
A0W34_RS31680	COG0183	Belongs to the thiolase family
A0W34_RS31685	COG1250	3-hydroxyacyl-CoA dehydrogenase
A0W34_RS31685	COG1024	Enoyl-CoA hydratase
A0W34_RS31695	COG1902	pentaerythritol trinitrate reductase activity
A0W34_RS31695	COG0446	pyridine nucleotide-disulphide oxidoreductase
A0W34_RS31760	COG2030	dehydratase
A0W34_RS31765	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A0W34_RS31830	COG0693	protein deglycase activity
A0W34_RS31835	COG1595	DNA-templated transcription, initiation
A0W34_RS31910	COG1074	ATP-dependent DNA helicase activity
A0W34_RS31955	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A0W34_RS31960	COG0477	Major facilitator Superfamily
A0W34_RS31965	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
A0W34_RS31985	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A0W34_RS32020	COG2184	nucleotidyltransferase activity
A0W34_RS32055	COG1017	nitric oxide dioxygenase activity
A0W34_RS32055	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A0W34_RS32060	COG1959	2 iron, 2 sulfur cluster binding
A0W34_RS32085	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A0W34_RS32110	COG1410	methionine synthase
A0W34_RS32110	COG0646	methionine synthase
A0W34_RS32120	COG1573	uracil-dna glycosylase
A0W34_RS32125	COG0288	reversible hydration of carbon dioxide
A0W34_RS32170	COG1570	exodeoxyribonuclease VII activity
A0W34_RS32230	COG0791	NLP P60 protein
A0W34_RS32230	COG1388	LysM domain
A0W34_RS32335	COG4974	Belongs to the 'phage' integrase family
A0W34_RS32420	COG0183	Belongs to the thiolase family
A0W34_RS32435	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A0W34_RS32440	COG0346	lactoylglutathione lyase activity
A0W34_RS32455	COG1414	Transcriptional regulator
A0W34_RS32460	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A0W34_RS32465	COG3328	transposase activity
A0W34_RS32505	COG5285	phytanoyl-CoA dioxygenase
A0W34_RS32515	COG1126	abc transporter atp-binding protein
A0W34_RS32520	COG0765	amino acid transport
A0W34_RS32525	COG0765	amino acid transport
A0W34_RS32530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A0W34_RS32565	COG2015	COG2015, Alkyl sulfatase and related hydrolases
A0W34_RS32580	COG3328	transposase activity
A0W34_RS32645	COG0006	proline dipeptidase activity