locus-tag	class	description
HFP48_RS00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
HFP48_RS00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HFP48_RS00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HFP48_RS00020	ENOG4105K7N	UPF0232 protein
HFP48_RS00040	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HFP48_RS00050	ENOG4105GWZ	Roadblock lc7 family protein
HFP48_RS00065	ENOG4105BZU	Histidine kinase
HFP48_RS00070	ENOG4105BZU	Histidine kinase
HFP48_RS00075	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HFP48_RS00100	ENOG4108V4B	ThiJ pfpI
HFP48_RS00105	ENOG4105YIP	Tetr family transcriptional regulator
HFP48_RS00130	ENOG4105DBE	peroxidase
HFP48_RS00135	ENOG4108CCU	Ribonucleotide-diphosphate reductase subunit beta
HFP48_RS00180	ENOG4107ZXI	Rhomboid family
HFP48_RS00205	ENOG4105D9P	serine threonine protein kinase
HFP48_RS00210	ENOG4107TPY	serine threonine protein kinase
HFP48_RS00215	ENOG4105CJN	penicillin-binding protein
HFP48_RS00230	ENOG4105HZM	Fha domain containing protein
HFP48_RS00235	ENOG4105TV9	FHA Domain-Containing protein
HFP48_RS00260	ENOG41061H0	Monooxygenase
HFP48_RS00270	ENOG4105CBC	glutamate synthase
HFP48_RS00295	ENOG4107TXC	Transcriptional regulator
HFP48_RS00310	ENOG41067V3	Antibiotic biosynthesis monooxygenase
HFP48_RS00330	ENOG4105CRK	lysyL-tRNA synthetase
HFP48_RS00345	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
HFP48_RS00355	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
HFP48_RS00375	ENOG4105CMD	Transcriptional regulator, GntR family
HFP48_RS00380	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HFP48_RS00385	ENOG4105CPQ	Dehydrogenase
HFP48_RS00390	ENOG4105C26	Dehydrogenase
HFP48_RS00400	ENOG4105CSH	Transporter
HFP48_RS00405	ENOG4105CMD	Transcriptional regulator, GntR family
HFP48_RS00420	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HFP48_RS00445	ENOG4105C26	Dehydrogenase
HFP48_RS00465	ENOG410846T	CoA-transferase family III
HFP48_RS00475	ENOG4105CEY	Amp-dependent synthetase and ligase
HFP48_RS00480	ENOG4105C1G	acyl-Coa dehydrogenase
HFP48_RS00490	ENOG4105CHU	acetyl-coa acetyltransferase
HFP48_RS00560	ENOG4105CGD	Nad-dependent epimerase dehydratase
HFP48_RS00570	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
HFP48_RS00575	ENOG410848D	S4 domain protein YaaA
HFP48_RS00590	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
HFP48_RS00655	ENOG4105CHU	acetyl-coa acetyltransferase
HFP48_RS00660	ENOG4105DXM	phenylacetic acid degradation protein
HFP48_RS00670	ENOG4105C1G	acyl-Coa dehydrogenase
HFP48_RS00675	ENOG4105E39	Enoyl-CoA hydratase
HFP48_RS00680	ENOG4105CEY	Amp-dependent synthetase and ligase
HFP48_RS00685	ENOG4105CHU	acetyl-coa acetyltransferase
HFP48_RS00695	ENOG4108X07	Tetr family transcriptional regulator
HFP48_RS00705	ENOG4106F59	XRE family Transcriptional regulator
HFP48_RS00755	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
HFP48_RS00765	ENOG4105BZU	Histidine kinase
HFP48_RS00780	ENOG4105F95	Monooxygenase
HFP48_RS00785	ENOG4108IG5	Transcriptional regulator
HFP48_RS00810	ENOG4108JIK	carboxylase
HFP48_RS00840	ENOG4106PMH	Extracellular solute-binding protein family 3
HFP48_RS00890	ENOG4107SFI	Major Facilitator superfamily
HFP48_RS00955	ENOG4108KGH	TRANSCRIPTIONal
HFP48_RS00970	ENOG4105DSF	transport protein
HFP48_RS01030	ENOG4105CGU	Enoyl-CoA hydratase
HFP48_RS01045	ENOG4105CHU	acetyl-coa acetyltransferase
HFP48_RS01065	ENOG4105CHR	reductase
HFP48_RS01105	ENOG4108UKI	Enoyl-CoA hydratase
HFP48_RS01165	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
HFP48_RS01170	ENOG4105E6M	Sulphatase-modifying factor protein
HFP48_RS01205	ENOG4105CBD	Diacylglycerol kinase
HFP48_RS01245	ENOG4105XTG	Pfam:DUF156
HFP48_RS01250	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
HFP48_RS01260	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HFP48_RS01300	ENOG4108RZE	Tetr family transcriptional regulator
HFP48_RS01310	ENOG4105C1G	acyl-Coa dehydrogenase
HFP48_RS01315	ENOG4105CHH	sulfate transporter
HFP48_RS01320	ENOG4108Z6Z	Transcriptional regulator
HFP48_RS01330	ENOG4105CSH	Transporter
HFP48_RS01355	ENOG4105CHR	reductase
HFP48_RS01390	ENOG4105JXB	ankyrin repeat-containing protein
HFP48_RS01395	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
HFP48_RS01420	ENOG4107B57	rieske 2fe-2S domain-containing protein
HFP48_RS01425	ENOG4105PSQ	Acyl-transferase
HFP48_RS01440	ENOG4105JFG	SpoIID LytB domain protein
HFP48_RS01445	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
HFP48_RS01475	ENOG4105KVH	Transcriptional regulator
HFP48_RS01480	ENOG4105TVB	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
HFP48_RS01495	ENOG4108MJN	Glycosyl Transferase
HFP48_RS01505	ENOG4107TXC	Transcriptional regulator
HFP48_RS01515	ENOG410602S	Transferase
HFP48_RS01525	ENOG4106YN8	Prenyltransferase
HFP48_RS01530	ENOG4107ISF	Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component the mycobacterial cell wall. Catalyzes the transfer of arabinofuranosyl (Araf) residues residue from the sugar donor beta-D-arabinofuranosyl-1-monophosphoryldecaprenol (DPA) to the arabinan domain to form terminal beta-(1- 2)-linked Araf residues, which marks the end point for AG arabinan biosynthesis before decoration with mycolic acids
HFP48_RS01540	ENOG4107YB1	Trehalose corynomycolyl transferase
HFP48_RS01555	ENOG4105FBW	Monooxygenase
HFP48_RS01560	ENOG4107RCI	amp-dependent synthetase and ligase
HFP48_RS01570	ENOG4105D8K	carboxyl transferase
HFP48_RS01585	ENOG4105J1Z	Arabinosyltransferase
HFP48_RS01590	ENOG4105J1Z	Arabinosyltransferase
HFP48_RS01605	ENOG4105CQB	FAD linked oxidase domain protein
HFP48_RS01615	ENOG4108K7T	Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component the mycobacterial cell wall. Catalyzes the addition of the first key arabinofuranosyl (Araf) residue from the sugar donor beta-D-arabinofuranosyl-1-monophosphoryldecaprenol (DPA) on the C-5 of a 6-linked galactofuranosyl (Galf) of the galactan domain, thus 'priming' the galactan for further elaboration by other arabinofuranosyltransferases
HFP48_RS01620	ENOG4108RG3	short-chain dehydrogenase reductase
HFP48_RS01625	ENOG4105IQ5	FAD linked oxidase domain protein
HFP48_RS01640	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
HFP48_RS01645	ENOG4107QPT	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
HFP48_RS01650	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
HFP48_RS01660	ENOG4105CKK	Glycosyl transferase, family 2
HFP48_RS01665	ENOG4105K64	Glycosyl transferase, family 2
HFP48_RS01675	ENOG410602S	Transferase
HFP48_RS01690	ENOG4108MKI	Glycosyl transferase, family 2
HFP48_RS01705	ENOG4108VC7	Protein of unknown function (DUF2587)
HFP48_RS01715	ENOG4105CPQ	Dehydrogenase
HFP48_RS01735	ENOG4107YB1	Trehalose corynomycolyl transferase
HFP48_RS01740	ENOG4107T31	5'-nucleotidase
HFP48_RS01745	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HFP48_RS01765	ENOG4107TPS	domain protein
HFP48_RS01770	ENOG4108VCT	Sulfite exporter TauE/SafE
HFP48_RS01780	ENOG4107RHI	Cytosine-specific methyltransferase
HFP48_RS01820	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HFP48_RS01825	ENOG4105EVN	Prephenate dehydrogenase
HFP48_RS01835	ENOG4108Z6B	deaminase
HFP48_RS01870	ENOG4105EYF	MMPL domain protein
HFP48_RS01905	ENOG4105CT3	Monooxygenase
HFP48_RS01930	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
HFP48_RS01950	ENOG4105F27	Major Facilitator
HFP48_RS01955	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
HFP48_RS01975	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
HFP48_RS01980	ENOG4105EJC	lysr family transcriptional regulator
HFP48_RS01995	ENOG4105W1N	transcriptional regulator
HFP48_RS02055	ENOG4105XT2	Transcriptional regulator
HFP48_RS02115	ENOG4108YIQ	Alpha beta hydrolase
HFP48_RS02140	ENOG4108ETV	ABC transporter
HFP48_RS02165	ENOG4105E39	Enoyl-CoA hydratase
HFP48_RS02170	ENOG4105CHU	acetyl-coa acetyltransferase
HFP48_RS02175	ENOG4105CHR	reductase
HFP48_RS02185	ENOG410900P	UPF0336 protein
HFP48_RS02195	ENOG4105C29	acyl-CoA thioesterase
HFP48_RS02200	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
HFP48_RS02215	ENOG4106YT9	Enoyl-CoA hydratase
HFP48_RS02220	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HFP48_RS02250	ENOG4105CHR	reductase
HFP48_RS02265	ENOG4105DPW	Major facilitator superfamily MFS_1
HFP48_RS02270	ENOG4105E39	Enoyl-CoA hydratase
HFP48_RS02280	ENOG4105CHU	acetyl-coa acetyltransferase
HFP48_RS02300	ENOG4105C1G	acyl-Coa dehydrogenase
HFP48_RS02310	ENOG4105EA8	2-Nitropropane dioxygenase
HFP48_RS02320	ENOG4105DND	Transcriptional regulator
HFP48_RS02325	ENOG4105DND	Transcriptional regulator
HFP48_RS02330	ENOG4105K4H	Nlp p60 protein
HFP48_RS02385	ENOG4105DTD	Dehydrogenase
HFP48_RS02395	ENOG4105DV0	amidase (EC 3.5.1.4
HFP48_RS02415	ENOG4105C26	Dehydrogenase
HFP48_RS02460	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HFP48_RS02465	ENOG4105VQD	rieske 2fe-2S domain-containing protein
HFP48_RS02470	ENOG4105C26	Dehydrogenase
HFP48_RS02520	ENOG4105WH1	Two component transcriptional regulator luxr family
HFP48_RS02525	ENOG4105CHU	acetyl-coa acetyltransferase
HFP48_RS02530	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HFP48_RS02540	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HFP48_RS02555	ENOG4108RU2	n-acetylmuramoyl-l-alanine amidase
HFP48_RS02565	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
HFP48_RS02570	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
HFP48_RS02590	ENOG4105C1G	acyl-Coa dehydrogenase
HFP48_RS02610	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
HFP48_RS02615	ENOG4105EA8	2-Nitropropane dioxygenase
HFP48_RS02620	ENOG4105CGU	Enoyl-CoA hydratase
HFP48_RS02645	ENOG4107PE3	Mammalian cell entry related domain protein
HFP48_RS02700	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
HFP48_RS02720	ENOG4106YT9	Enoyl-CoA hydratase
HFP48_RS02730	ENOG4107QXN	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HFP48_RS02745	ENOG4105CFH	Aspartokinase
HFP48_RS02765	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
HFP48_RS02770	ENOG4105EW9	transcriptional regulator AsnC family
HFP48_RS02775	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
HFP48_RS02780	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HFP48_RS02790	ENOG4105ERH	Fumarylacetoacetate hydrolase
HFP48_RS02810	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
HFP48_RS02850	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
HFP48_RS02860	ENOG4105IW1	AmiS UreI transporter
HFP48_RS02880	ENOG4108UAJ	Transcriptional regulator
HFP48_RS02915	ENOG4105CHR	reductase
HFP48_RS02925	ENOG4105CPQ	Dehydrogenase
HFP48_RS02935	ENOG4105ETE	Transcriptional regulator (LacI family
HFP48_RS03005	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
HFP48_RS03010	ENOG4107RSS	Hydrogenase accessory protein HypB
HFP48_RS03020	ENOG4105DPX	Hydrogenase, large subunit
HFP48_RS03025	ENOG41083MR	nifu domain-containing protein
HFP48_RS03050	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
HFP48_RS03065	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
HFP48_RS03070	ENOG4105C45	hydrogenase expression formation protein (HypE)
HFP48_RS03075	ENOG41082MF	Hydrogenase assembly chaperone hypC hupF
HFP48_RS03090	ENOG4108JJB	ABC transporter
HFP48_RS03105	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
HFP48_RS03125	ENOG4105JAB	phenazine biosynthesis protein, phzf family
HFP48_RS03130	ENOG4105CSH	Transporter
HFP48_RS03135	ENOG4105CEY	Amp-dependent synthetase and ligase
HFP48_RS03140	ENOG4105C1G	acyl-Coa dehydrogenase
HFP48_RS03145	ENOG4108RF4	Tetr family transcriptional regulator
HFP48_RS03150	ENOG4107RN6	Monooxygenase
HFP48_RS03180	ENOG4105CH6	catalase
HFP48_RS03215	ENOG4108MES	Periplasmic binding protein
HFP48_RS03240	ENOG4105DIN	metallophosphoesterase
HFP48_RS03255	ENOG4105N0U	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
HFP48_RS03280	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
HFP48_RS03315	ENOG4107S9D	Alpha beta hydrolase
HFP48_RS03325	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
HFP48_RS03330	ENOG4105CSH	Transporter
HFP48_RS03335	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HFP48_RS03385	ENOG4108I5C	dEAD DEAH box helicase
HFP48_RS03390	ENOG4105VEQ	Cold shock protein
HFP48_RS03400	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HFP48_RS03415	ENOG4107QRG	dna polymerase iii
HFP48_RS03490	ENOG4105C9B	Cysteine desulfurase
HFP48_RS03495	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
HFP48_RS03530	ENOG4107RD1	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
HFP48_RS03540	ENOG4105D9P	serine threonine protein kinase
HFP48_RS03545	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HFP48_RS03550	ENOG4105EUJ	GTP cyclohydrolase i
HFP48_RS03555	ENOG4105EEI	dihydropteroate synthase
HFP48_RS03585	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
HFP48_RS03590	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
HFP48_RS03595	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
HFP48_RS03605	ENOG4105CRK	lysyL-tRNA synthetase
HFP48_RS03615	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
HFP48_RS03640	ENOG4105FDT	acyl-CoA dehydrogenase
HFP48_RS03660	ENOG4105PMW	Domain of unknown function (DUF1990)
HFP48_RS03680	ENOG4108V9Q	carbonic anhydrase
HFP48_RS03690	ENOG4105E59	Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity)
HFP48_RS03700	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HFP48_RS03705	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
HFP48_RS03715	ENOG4108VJ1	Transcriptional regulator (CarD family
HFP48_RS03720	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
HFP48_RS03725	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
HFP48_RS03730	ENOG4105C8N	cysteinyl-tRNA synthetase
HFP48_RS03745	ENOG4107R7A	Allophanate hydrolase subunit 2
HFP48_RS03765	ENOG4105CC5	ABC transporter
HFP48_RS03770	ENOG4105DIK	(ABC) transporter
HFP48_RS03775	ENOG4105DSE	periplasmic solute binding protein
HFP48_RS03785	ENOG4105BZP	glycoside hydrolase 15-related
HFP48_RS03790	ENOG4108SGK	Tetr family transcriptional regulator
HFP48_RS03795	ENOG4105D2B	acyl-CoA dehydrogenase
HFP48_RS03800	ENOG4108RK3	acyl-Coa dehydrogenase
HFP48_RS03805	ENOG4105X7H	acyl-CoA dehydrogenase
HFP48_RS03810	ENOG410900P	UPF0336 protein
HFP48_RS03830	ENOG4108R85	Short chain dehydrogenase
HFP48_RS03850	ENOG4105C8P	)-transporter
HFP48_RS03920	ENOG4105DQE	DNA ligase
HFP48_RS03925	ENOG4105CSH	Transporter
HFP48_RS03930	ENOG4107HP6	Transcriptional regulator
HFP48_RS03940	ENOG4105D6Z	AFG1 family ATPase
HFP48_RS03960	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
HFP48_RS03965	ENOG4105IKQ	hydratase
HFP48_RS03970	ENOG4105DIV	Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (By similarity)
HFP48_RS03975	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
HFP48_RS03990	ENOG4105MC2	DSBA oxidoreductase
HFP48_RS03995	ENOG4105WH1	Two component transcriptional regulator luxr family
HFP48_RS04000	ENOG4105BZU	Histidine kinase
HFP48_RS04015	ENOG4105CNG	UPF0061 protein
HFP48_RS04055	ENOG4108KC1	acyl-Coa dehydrogenase
HFP48_RS04060	ENOG41088PD	hydrolase
HFP48_RS04065	ENOG4105H37	Glyoxalase Bleomycin resistance protein (Dioxygenase
HFP48_RS04070	ENOG4105MXW	flavin reductase domain protein, FMN-binding
HFP48_RS04090	ENOG4105CV8	reductase
HFP48_RS04095	ENOG4105D2B	acyl-CoA dehydrogenase
HFP48_RS04100	ENOG4105D2B	acyl-CoA dehydrogenase
HFP48_RS04105	ENOG4105CC9	acyl-Coa dehydrogenase
HFP48_RS04115	ENOG4105CEY	Amp-dependent synthetase and ligase
HFP48_RS04120	ENOG4105CC9	acyl-Coa dehydrogenase
HFP48_RS04130	ENOG4108RZE	Tetr family transcriptional regulator
HFP48_RS04135	ENOG4105F2C	Acetyl-CoA acetyltransferase
HFP48_RS04145	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
HFP48_RS04150	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
HFP48_RS04165	ENOG4107S2E	monooxygenase
HFP48_RS04170	ENOG4105EBR	Carboxylesterase
HFP48_RS04175	ENOG4107S9F	NmrA family
HFP48_RS04180	ENOG4105EA8	2-Nitropropane dioxygenase
HFP48_RS04195	ENOG4105E39	Enoyl-CoA hydratase
HFP48_RS04200	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
HFP48_RS04205	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HFP48_RS04215	ENOG4105F2C	Acetyl-CoA acetyltransferase
HFP48_RS04220	ENOG4106A3M	Cytochrome p-450
HFP48_RS04225	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
HFP48_RS04265	ENOG4105DYW	oxidoreductase
HFP48_RS04295	ENOG4107TXC	Transcriptional regulator
HFP48_RS04305	ENOG4105J5T	Amp-dependent synthetase and ligase
HFP48_RS04310	ENOG4108KC2	acyl-Coa dehydrogenase
HFP48_RS04315	ENOG4105X7H	acyl-CoA dehydrogenase
HFP48_RS04325	ENOG4105CHR	reductase
HFP48_RS04385	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
HFP48_RS04400	ENOG4105BZ1	(ABC) transporter
HFP48_RS04410	ENOG4105K51	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
HFP48_RS04425	ENOG4105CSH	Transporter
HFP48_RS04450	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
HFP48_RS04460	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
HFP48_RS04465	ENOG4105DH8	myo-inositol catabolism
HFP48_RS04475	ENOG4105EDK	PfkB domain protein
HFP48_RS04485	ENOG4105CHU	acetyl-coa acetyltransferase
HFP48_RS04520	ENOG4105D2B	acyl-CoA dehydrogenase
HFP48_RS04525	ENOG4105D2B	acyl-CoA dehydrogenase
HFP48_RS04530	ENOG4105CEY	Amp-dependent synthetase and ligase
HFP48_RS04535	ENOG4105C29	acyl-CoA thioesterase
HFP48_RS04560	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
HFP48_RS04570	ENOG4105F1Y	L-lysine 6-monooxygenase (NADPH)
HFP48_RS04590	ENOG4105VTR	Integrase
HFP48_RS04920	ENOG4105GRZ	Ycii-related protein
HFP48_RS04925	ENOG4105CHP	RNA polymerase
HFP48_RS04950	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
HFP48_RS04975	ENOG4105CHR	reductase
HFP48_RS05005	ENOG4105D2S	major facilitator superfamily
HFP48_RS05020	ENOG4105CHR	reductase
HFP48_RS05035	ENOG410846T	CoA-transferase family III
HFP48_RS05040	ENOG4105CEY	Amp-dependent synthetase and ligase
HFP48_RS05065	ENOG4105DXM	phenylacetic acid degradation protein
HFP48_RS05070	ENOG4105CHU	acetyl-coa acetyltransferase
HFP48_RS05080	ENOG4105CEY	Amp-dependent synthetase and ligase
HFP48_RS05085	ENOG4105CHU	acetyl-coa acetyltransferase
HFP48_RS05090	ENOG4105E39	Enoyl-CoA hydratase
HFP48_RS05100	ENOG4108RZE	Tetr family transcriptional regulator
HFP48_RS05125	ENOG4108DT4	serine threonine protein kinase
HFP48_RS05130	ENOG4105EWK	phytoene
HFP48_RS05160	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HFP48_RS05165	ENOG4105BZU	Histidine kinase
HFP48_RS05190	ENOG4105CHM	Aminotransferase
HFP48_RS05200	ENOG4105C83	adenylosuccinate lyase
HFP48_RS05205	ENOG41062JF	Transcriptional regulator
HFP48_RS05230	ENOG4105CSH	Transporter
HFP48_RS05235	ENOG4105K56	Transcriptional regulator
HFP48_RS05265	ENOG4105H3G	oxidoreductase
HFP48_RS05275	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HFP48_RS05280	ENOG4108MRH	transcriptional regulatory protein
HFP48_RS05290	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
HFP48_RS05305	ENOG4105SHT	UspA domain-containing protein
HFP48_RS05330	ENOG4105BZ1	(ABC) transporter
HFP48_RS05335	ENOG4105WQI	isochorismatase
HFP48_RS05340	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
HFP48_RS05345	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
HFP48_RS05355	ENOG4105CEY	Amp-dependent synthetase and ligase
HFP48_RS05360	ENOG4105F7P	transcriptional regulator AsnC family
HFP48_RS05385	ENOG4105WQI	isochorismatase
HFP48_RS05390	ENOG4105E8G	Major facilitator Superfamily
HFP48_RS05400	ENOG4105C26	Dehydrogenase
HFP48_RS05425	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HFP48_RS05435	ENOG4105NPE	arsR family transcriptional regulator
HFP48_RS05475	ENOG4105Q26	Siderophore-interacting protein
HFP48_RS05480	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HFP48_RS05485	ENOG4105C8V	SAICAR synthetase
HFP48_RS05495	ENOG4108V9W	transcriptional regulatory protein
HFP48_RS05500	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
HFP48_RS05505	ENOG4107QJT	sodium dicarboxylate symporter
HFP48_RS05510	ENOG4105DU0	nucleoside hydrolase
HFP48_RS05520	ENOG4105C5Q	Transcriptional regulator
HFP48_RS05525	ENOG4108JU3	Alkyl hydroperoxide reductase
HFP48_RS05530	ENOG4105D3R	alkyl hydroperoxide reductase
HFP48_RS05535	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HFP48_RS05570	ENOG4108KTG	Membrane protein, drug metabolite transporter
HFP48_RS05600	ENOG4105CSH	Transporter
HFP48_RS05605	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
HFP48_RS05610	ENOG4105CEY	Amp-dependent synthetase and ligase
HFP48_RS05620	ENOG4105C26	Dehydrogenase
HFP48_RS05650	ENOG4105WH1	Two component transcriptional regulator luxr family
HFP48_RS05660	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
HFP48_RS05680	ENOG4105EHG	Permease protein
HFP48_RS05685	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
HFP48_RS05745	ENOG4107R16	Multicopper oxidase
HFP48_RS05765	ENOG4108V06	Glutathione peroxidase
HFP48_RS05770	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
HFP48_RS05795	ENOG4105EBR	Carboxylesterase
HFP48_RS05825	ENOG410839H	phosphoribosylformylglycinamidine synthase
HFP48_RS05830	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
HFP48_RS05835	ENOG41062D9	Histidine kinase
HFP48_RS05840	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HFP48_RS05875	ENOG4105DFM	M18 family aminopeptidase
HFP48_RS05885	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
HFP48_RS05910	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
HFP48_RS05940	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HFP48_RS05945	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HFP48_RS05950	ENOG4108JJ9	ABC, transporter
HFP48_RS05955	ENOG4108JJ8	(ABC) transporter
HFP48_RS05960	ENOG4108SVG	May play a role in the intracellular transport of hydrophobic ligands
HFP48_RS05970	ENOG4105PKJ	carbohydrate binding
HFP48_RS05975	ENOG4105KHC	sulfurtransferase
HFP48_RS05995	ENOG4107NHD	transcriptional regulator
HFP48_RS06000	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
HFP48_RS06015	ENOG4105E2Z	phosphate ABC transporter (Permease
HFP48_RS06020	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
HFP48_RS06065	ENOG41064MX	Tetr family transcriptional regulator
HFP48_RS06090	ENOG4105CEY	Amp-dependent synthetase and ligase
HFP48_RS06100	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HFP48_RS06105	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HFP48_RS06120	ENOG4105CHR	reductase
HFP48_RS06145	ENOG4108IG5	Transcriptional regulator
HFP48_RS06150	ENOG4105FUY	alpha subunit
HFP48_RS06155	ENOG4105CGU	Enoyl-CoA hydratase
HFP48_RS06165	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HFP48_RS06175	ENOG4105D2S	major facilitator superfamily
HFP48_RS06180	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
HFP48_RS06185	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
HFP48_RS06190	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HFP48_RS06195	ENOG4105EQH	reductase
HFP48_RS06210	ENOG4105CSH	Transporter
HFP48_RS06215	ENOG4107QY8	reductase
HFP48_RS06230	ENOG4105DYW	oxidoreductase
HFP48_RS06280	ENOG41076PI	Short-chain dehydrogenase reductase Sdr
HFP48_RS06320	ENOG4105D2S	major facilitator superfamily
HFP48_RS06330	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HFP48_RS06350	ENOG4105C1G	acyl-Coa dehydrogenase
HFP48_RS06355	ENOG4105FUY	alpha subunit
HFP48_RS06360	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
HFP48_RS06385	ENOG4105CHR	reductase
HFP48_RS06390	ENOG4105E3J	oxidoreductase
HFP48_RS06395	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HFP48_RS06400	ENOG4105CEY	Amp-dependent synthetase and ligase
HFP48_RS06405	ENOG4105CGU	Enoyl-CoA hydratase
HFP48_RS06420	ENOG4106A3M	Cytochrome p-450
HFP48_RS06435	ENOG4105EMU	Dehydrogenase
HFP48_RS06465	ENOG4107EFR	Flavocytochrome c
HFP48_RS06475	ENOG4108SGK	Tetr family transcriptional regulator
HFP48_RS06490	ENOG4105C8J	)-transporter
HFP48_RS06500	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
HFP48_RS06520	ENOG4108YV4	Universal stress protein
HFP48_RS06585	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
HFP48_RS06605	ENOG4107ZYR	domain protein
HFP48_RS06610	ENOG4105CZN	Potassium uptake protein
HFP48_RS06630	ENOG4108ZHJ	Organic hydroperoxide resistance protein
HFP48_RS06635	ENOG4105K56	Transcriptional regulator
HFP48_RS06660	ENOG4105C3M	thioredoxin reductase
HFP48_RS06675	ENOG4105CG3	alpha amylase, catalytic region
HFP48_RS06680	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HFP48_RS06685	ENOG4105K64	Glycosyl transferase, family 2
HFP48_RS06690	ENOG4105EV8	ectoine hydroxylase
HFP48_RS06730	ENOG4108KPJ	rna polymerase sigma factor
HFP48_RS06785	ENOG4105D4T	Citrate transporter
HFP48_RS06790	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
HFP48_RS06795	ENOG4106YYS	transcriptional regulatory protein
HFP48_RS06815	ENOG4105MS9	Resuscitation-promoting factor
HFP48_RS06830	ENOG4105VEQ	Cold shock protein
HFP48_RS06840	ENOG4108N0W	Major Facilitator superfamily
HFP48_RS06860	ENOG410841Q	phosphoesterase PA-phosphatase related protein
HFP48_RS06870	ENOG4105C7N	Xanthine uracil vitamin C permease
HFP48_RS06875	ENOG4105XMC	MarR family Transcriptional regulator
HFP48_RS06900	ENOG4107R8H	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
HFP48_RS06910	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
HFP48_RS06915	ENOG4105E8G	Major facilitator Superfamily
HFP48_RS06930	ENOG4106NZI	LysR family Transcriptional regulator
HFP48_RS06940	ENOG4107WI4	Aldose-1-epimerase
HFP48_RS06950	ENOG41081K0	peptidylprolyl cis-trans isomerase
HFP48_RS06960	ENOG4108TAG	Histidine kinase
HFP48_RS06970	ENOG4105MKU	Transcriptional regulator
HFP48_RS06975	ENOG4105CSU	acyl-Coa dehydrogenase
HFP48_RS06995	ENOG4108NBA	ATP-dependent carboxylate-amine ligase (By similarity)
HFP48_RS07010	ENOG4107S2Z	UPF0761 membrane protein
HFP48_RS07020	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HFP48_RS07030	ENOG4105RHA	ABC transporter, permease
HFP48_RS07035	ENOG4108IUX	(ABC) transporter
HFP48_RS07055	ENOG4105C5H	ABC transporter
HFP48_RS07060	ENOG4105CV8	reductase
HFP48_RS07075	ENOG4105H3G	oxidoreductase
HFP48_RS07110	ENOG4107RSM	transcriptional regulator
HFP48_RS07120	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
HFP48_RS07140	ENOG41064MX	Tetr family transcriptional regulator
HFP48_RS07150	ENOG4105E39	Enoyl-CoA hydratase
HFP48_RS07165	ENOG4105C1G	acyl-Coa dehydrogenase
HFP48_RS07175	ENOG4105CHR	reductase
HFP48_RS07180	ENOG4108IPT	Naphthoate synthase
HFP48_RS07185	ENOG4105CHU	acetyl-coa acetyltransferase
HFP48_RS07190	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HFP48_RS07195	ENOG4105D2S	major facilitator superfamily
HFP48_RS07200	ENOG4105C1G	acyl-Coa dehydrogenase
HFP48_RS07205	ENOG4105EEQ	Na H antiporter
HFP48_RS07210	ENOG4105D22	carbon starvation protein
HFP48_RS07225	ENOG4108HRK	Histidine kinase
HFP48_RS07230	ENOG4105DY9	regulatoR
HFP48_RS07240	ENOG4107QN1	sodium solute
HFP48_RS07250	ENOG4107QN1	sodium solute
HFP48_RS07265	ENOG4107VUZ	
HFP48_RS07270	ENOG4105KK4	UPF0060 membrane protein
HFP48_RS07285	ENOG4105DMF	Dehydrogenase
HFP48_RS07300	ENOG4105XTG	Pfam:DUF156
HFP48_RS07340	ENOG4105DR5	peptidase
HFP48_RS07360	ENOG41081JD	Transcriptional regulator
HFP48_RS07365	ENOG4105CJW	magnesium transporter
HFP48_RS07375	ENOG4105DYW	oxidoreductase
HFP48_RS07440	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
HFP48_RS07455	ENOG4105EBR	Carboxylesterase
HFP48_RS07465	ENOG4108SGK	Tetr family transcriptional regulator
HFP48_RS07470	ENOG4105CSU	acyl-Coa dehydrogenase
HFP48_RS07480	ENOG4107QP8	phosphohexose isomerase
HFP48_RS07500	ENOG4105DR5	peptidase
HFP48_RS07510	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
HFP48_RS07520	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
HFP48_RS07560	ENOG4105EET	magnesium chelatase
HFP48_RS07580	ENOG4105RK9	auxin efflux carrier
HFP48_RS07590	ENOG41080U6	GntR family transcriptional regulator
HFP48_RS07605	ENOG4106ZX3	phosphonate ABC transporter, periplasmic phosphonate-binding protein
HFP48_RS07610	ENOG4105D5T	phosphonate abc transporter
HFP48_RS07615	ENOG4105S7S	phosphonate abc transporter
HFP48_RS07620	ENOG4105CPQ	Dehydrogenase
HFP48_RS07630	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
HFP48_RS07635	ENOG41080FR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
HFP48_RS07640	ENOG4105W0E	50S ribosomal protein L33
HFP48_RS07645	ENOG4105KDC	50s ribosomal protein l28
HFP48_RS07655	ENOG4105NRA	50s ribosomal protein l31 type b
HFP48_RS07680	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HFP48_RS07710	ENOG41080UU	5-formyltetrahydrofolate cyclo-ligase
HFP48_RS07715	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
HFP48_RS07725	ENOG4105D9U	N-acetyltransferase
HFP48_RS07735	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HFP48_RS07760	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HFP48_RS07775	ENOG4105WH1	Two component transcriptional regulator luxr family
HFP48_RS07785	ENOG4105CEU	Arginine dihydrolase
HFP48_RS07800	ENOG41080FJ	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
HFP48_RS07805	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
HFP48_RS07810	ENOG4105C94	Transporter
HFP48_RS07830	ENOG4105BZG	amino acid carrier protein
HFP48_RS07835	ENOG4108HMN	Caspase domain
HFP48_RS07845	ENOG4108KPJ	rna polymerase sigma factor
HFP48_RS07865	ENOG4105F8V	Hydrolase, tatD family
HFP48_RS07875	ENOG4105EUB	pirin domain protein
HFP48_RS07880	ENOG4108UYE	Lactoylglutathione lyase
HFP48_RS07885	ENOG4108VGI	doxx family
HFP48_RS07890	ENOG4105CDA	abc transporter atp-binding protein
HFP48_RS07895	ENOG4105E5Q	amino acid AbC transporter
HFP48_RS07900	ENOG4106839	domain protein
HFP48_RS07905	ENOG4106839	domain protein
HFP48_RS07910	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
HFP48_RS07915	ENOG4105VEQ	Cold shock protein
HFP48_RS07920	ENOG4105VEQ	Cold shock protein
HFP48_RS07930	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
HFP48_RS07935	ENOG4105C5H	ABC transporter
HFP48_RS07950	ENOG4105C1G	acyl-Coa dehydrogenase
HFP48_RS07990	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
HFP48_RS07995	ENOG4107RCI	amp-dependent synthetase and ligase
HFP48_RS08000	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
HFP48_RS08005	ENOG4107XT7	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
HFP48_RS08010	ENOG4107EFR	Flavocytochrome c
HFP48_RS08025	ENOG4105D1K	glutamate--cysteine ligase
HFP48_RS08030	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
HFP48_RS08035	ENOG4108V75	Glutamine amidotransferase
HFP48_RS08040	ENOG41067HS	methyltransferase
HFP48_RS08050	ENOG4105DXI	Major Facilitator superfamily
HFP48_RS08055	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HFP48_RS08080	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HFP48_RS08090	ENOG41067SE	Tetr family transcriptional regulator
HFP48_RS08095	ENOG41064MX	Tetr family transcriptional regulator
HFP48_RS08115	ENOG4105DXN	mazG family
HFP48_RS08130	ENOG4105D9U	N-acetyltransferase
HFP48_RS08140	ENOG4107MV2	Inherit from COG: Hemolysin-type calcium-binding
HFP48_RS08170	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HFP48_RS08180	ENOG4105D3Q	Sugar transferase
HFP48_RS08190	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
HFP48_RS08205	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
HFP48_RS08240	ENOG4105DBE	peroxidase
HFP48_RS08250	ENOG4105EKT	)-iron permease
HFP48_RS08260	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
HFP48_RS08360	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
HFP48_RS08365	ENOG4108159	Pfam:UPF0005
HFP48_RS08385	ENOG4107SN7	NLP P60 protein
HFP48_RS08390	ENOG4107YD5	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HFP48_RS08400	ENOG4105T1M	mycothiol conjugate amidase mca
HFP48_RS08410	ENOG4105C7Z	Conserved Protein
HFP48_RS08415	ENOG4105D8X	mechanosensitive ion channel
HFP48_RS08425	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
HFP48_RS08430	ENOG4105CS9	pantothenic acid kinase
HFP48_RS08440	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
HFP48_RS08445	ENOG4108IAB	Phoh family
HFP48_RS08455	ENOG4105MXB	limonene-12-epoxide hydrolase
HFP48_RS08460	ENOG4107S1E	Beta-lactamase
HFP48_RS08470	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
HFP48_RS08475	ENOG4105CHR	reductase
HFP48_RS08490	ENOG4105CSH	Transporter
HFP48_RS08495	ENOG4105CEY	Amp-dependent synthetase and ligase
HFP48_RS08520	ENOG4105YX8	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HFP48_RS08525	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HFP48_RS08535	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
HFP48_RS08555	ENOG4105EYH	Exonuclease
HFP48_RS08570	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
HFP48_RS08575	ENOG4105C3G	gtp-binding protein
HFP48_RS08580	ENOG4105D3G	Pseudouridine synthase
HFP48_RS08610	ENOG4105CQB	FAD linked oxidase domain protein
HFP48_RS08630	ENOG41082BM	Transcriptional regulator, arsr family
HFP48_RS08640	ENOG4105DSY	exodeoxyribonuclease V, gamma
HFP48_RS08645	ENOG4107QKA	exodeoxyribonuclease V beta
HFP48_RS08650	ENOG4105C7H	Helicase, RecD TraA family
HFP48_RS08660	ENOG41086VY	Fic/DOC family
HFP48_RS08665	ENOG4105H3G	oxidoreductase
HFP48_RS08670	ENOG4108Q9V	regulatoR
HFP48_RS08675	ENOG4105C4B	ABC transporter, permease
HFP48_RS08685	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HFP48_RS08690	ENOG41076PI	Short-chain dehydrogenase reductase Sdr
HFP48_RS08695	ENOG4105WBV	Transcriptional regulator
HFP48_RS08710	ENOG4107RYT	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair (By similarity)
HFP48_RS08740	ENOG4105CPQ	Dehydrogenase
HFP48_RS08745	ENOG4105DEI	Mannitol dehydrogenase
HFP48_RS08770	ENOG41079KZ	Major Facilitator Superfamily
HFP48_RS08785	ENOG4105J4Q	Transcriptional regulator
HFP48_RS08790	ENOG4105IKQ	hydratase
HFP48_RS08800	ENOG41069HH	4-oxalocrotonate tautomerase
HFP48_RS08855	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
HFP48_RS08860	ENOG4105DIV	Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (By similarity)
HFP48_RS08870	ENOG4108KPJ	rna polymerase sigma factor
HFP48_RS08890	ENOG4107GFK	fumarate
HFP48_RS08930	ENOG4108WKN	secreted protein
HFP48_RS08935	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HFP48_RS08950	ENOG4108U8T	Mannosyltransferase
HFP48_RS08955	ENOG410842T	Pterin carbinolamine dehydratase
HFP48_RS08970	ENOG4105CI3	gtp-binding protein typa
HFP48_RS08975	ENOG4107USK	Extracellular solute-binding protein, family 5
HFP48_RS08980	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
HFP48_RS09015	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
HFP48_RS09025	ENOG4108Z4U	Ferredoxin
HFP48_RS09035	ENOG4105C26	Dehydrogenase
HFP48_RS09065	ENOG4105C85	amino acid
HFP48_RS09070	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
HFP48_RS09075	ENOG4107R4C	succinyl-diaminopimelate desuccinylase
HFP48_RS09080	ENOG4108URH	decarboxylase
HFP48_RS09090	ENOG4105CEY	Amp-dependent synthetase and ligase
HFP48_RS09095	ENOG4105EEI	dihydropteroate synthase
HFP48_RS09100	ENOG4105C3Q	Glycosyl transferase, family 2
HFP48_RS09110	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HFP48_RS09125	ENOG4107QPH	glycogen) synthase
HFP48_RS09130	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
HFP48_RS09135	ENOG4107ZBN	O-methyltransferase
HFP48_RS09140	ENOG4105DU6	RNA polymerase
HFP48_RS09145	ENOG4106684	
HFP48_RS09150	ENOG4105C0H	protease
HFP48_RS09155	ENOG4105UTW	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
HFP48_RS09180	ENOG4105CJW	magnesium transporter
HFP48_RS09185	ENOG4105CI0	Citrate lyase
HFP48_RS09220	ENOG4105DP8	Major facilitator superfamily MFS_1
HFP48_RS09235	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HFP48_RS09255	ENOG4105D7N	magnesium and cobalt transport protein CorA
HFP48_RS09260	ENOG4105DB7	PHP domain protein
HFP48_RS09290	ENOG4105F95	Monooxygenase
HFP48_RS09295	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
HFP48_RS09300	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
HFP48_RS09305	ENOG4105BZ1	(ABC) transporter
HFP48_RS09320	ENOG4108YIQ	Alpha beta hydrolase
HFP48_RS09340	ENOG4105CHF	Glutathione S-transferase
HFP48_RS09360	ENOG4105CEY	Amp-dependent synthetase and ligase
HFP48_RS09415	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
HFP48_RS09445	ENOG4105BZ1	(ABC) transporter
HFP48_RS09450	ENOG410905P	Pyridoxamine 5-phosphate
HFP48_RS09465	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HFP48_RS09470	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HFP48_RS09490	ENOG4108WC5	Alpha Beta Hydrolase Fold protein
HFP48_RS09495	ENOG4105CPI	Metal Dependent Phosphohydrolase
HFP48_RS09500	ENOG4105GYP	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity)
HFP48_RS09510	ENOG4105BZW	Glycerate kinase
HFP48_RS09515	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
HFP48_RS09520	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HFP48_RS09565	ENOG4105C1G	acyl-Coa dehydrogenase
HFP48_RS09575	ENOG4105DTQ	mandelate racemase muconate lactonizing
HFP48_RS09580	ENOG410846T	CoA-transferase family III
HFP48_RS09590	ENOG4105CSH	Transporter
HFP48_RS09600	ENOG4105CSH	Transporter
HFP48_RS09635	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HFP48_RS09640	ENOG4105D5U	fad dependent oxidoreductase
HFP48_RS09650	ENOG4105D2S	major facilitator superfamily
HFP48_RS09655	ENOG4105J4Q	Transcriptional regulator
HFP48_RS09665	ENOG4105ERH	Fumarylacetoacetate hydrolase
HFP48_RS09680	ENOG4105CPQ	Dehydrogenase
HFP48_RS09685	ENOG4105D3W	isochorismatase
HFP48_RS09725	ENOG4105CHR	reductase
HFP48_RS09735	ENOG4108JNI	Alpha beta hydrolase
HFP48_RS09745	ENOG4108KB2	LysR family Transcriptional regulator
HFP48_RS09765	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HFP48_RS09770	ENOG4105CHR	reductase
HFP48_RS09775	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HFP48_RS09810	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
HFP48_RS09845	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
HFP48_RS09855	ENOG4105KRG	Aromatic-ring-hydroxylating dioxygenase beta subunit
HFP48_RS09865	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
HFP48_RS09870	ENOG4105CAY	ferredoxin--nadp reductase
HFP48_RS09895	ENOG4107TYC	hydantoinase B oxoprolinase
HFP48_RS09910	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
HFP48_RS09940	ENOG4105K4P	CoA-binding domain protein
HFP48_RS09950	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
HFP48_RS09975	ENOG4105CEY	Amp-dependent synthetase and ligase
HFP48_RS09985	ENOG4107HP6	Transcriptional regulator
HFP48_RS09995	ENOG4108K8K	Transcriptional regulator
HFP48_RS10010	ENOG4105H37	Glyoxalase Bleomycin resistance protein (Dioxygenase
HFP48_RS10015	ENOG4105FUY	alpha subunit
HFP48_RS10020	ENOG4108SBK	dioxygenase, subunit beta
HFP48_RS10045	ENOG4105IKQ	hydratase
HFP48_RS10050	ENOG4107HP6	Transcriptional regulator
HFP48_RS10085	ENOG4105CI0	Citrate lyase
HFP48_RS10090	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HFP48_RS10130	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
HFP48_RS10180	ENOG4105GSW	
HFP48_RS10225	ENOG4105ETE	Transcriptional regulator (LacI family
HFP48_RS10230	ENOG4105EQP	Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity)
HFP48_RS10240	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HFP48_RS10250	ENOG4108UAU	isochorismatase
HFP48_RS10265	ENOG4107R9N	ABC transporter
HFP48_RS10270	ENOG4108UZX	fmn reductase
HFP48_RS10280	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
HFP48_RS10315	ENOG4105HHS	UPF0256 protein
HFP48_RS10335	ENOG4105CSR	polyphosphate kinase 2
HFP48_RS10400	ENOG4108IQE	Amp-dependent synthetase and ligase
HFP48_RS10410	ENOG4105WH1	Two component transcriptional regulator luxr family
HFP48_RS10440	ENOG4105E2Y	ABC, transporter
HFP48_RS10445	ENOG4108I05	Binding-protein-dependent transport systems, inner membrane component
HFP48_RS10455	ENOG4105DWF	phosphomethylpyrimidine kinase
HFP48_RS10460	ENOG4105EBR	Carboxylesterase
HFP48_RS10495	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
HFP48_RS10535	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
HFP48_RS10545	ENOG4105K78	MarR family Transcriptional regulator
HFP48_RS10550	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HFP48_RS10555	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HFP48_RS10560	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HFP48_RS10575	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
HFP48_RS10580	ENOG4105CPP	Dehydrogenase, E1 component
HFP48_RS10595	ENOG4105CHU	acetyl-coa acetyltransferase
HFP48_RS10605	ENOG4105DKK	Benzoate
HFP48_RS10615	ENOG4105F9E	Shikimate 5-dehydrogenase
HFP48_RS10630	ENOG4105C0D	helicase
HFP48_RS10640	ENOG4105C26	Dehydrogenase
HFP48_RS10650	ENOG4105E39	Enoyl-CoA hydratase
HFP48_RS10670	ENOG4107ZF2	Phosphatase
HFP48_RS10695	ENOG4105C11	sulfate adenylyltransferase), subunit 2
HFP48_RS10705	ENOG4108RM3	Phosphatase with a broad specificity. Its primary physiological function is to dephosphorylate 3'-phosphoadenosine 5'-phosphate (PAP) and 3'-phosphoadenosine 5'-phosphosulfate (PAPS). Thus, plays a role in mycobacterial sulfur metabolism, since it can serve as a key regulator of the sulfate assimilation pathway by controlling the pools of PAP and PAPS in the cell. To a lesser extent, is also able to hydrolyze inositol 1-phosphate (I- 1-P), fructose 1,6-bisphosphate (FBP) (to fructose 6-phosphate (F- 6-P)) and AMP in vitro, but this might has no significance in vivo
HFP48_RS10730	ENOG4107QRI	Phosphoketolase
HFP48_RS10745	ENOG4105C75	arginyL-tRNA synthetase
HFP48_RS10750	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
HFP48_RS10755	ENOG4105D6E	homoserine dehydrogenase
HFP48_RS10760	ENOG4107R5I	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
HFP48_RS10765	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
HFP48_RS10775	ENOG4105VFB	Binds the 23S rRNA (By similarity)
HFP48_RS10780	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
HFP48_RS10790	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HFP48_RS10800	ENOG4105ESV	Glycosyl transferase, family 4
HFP48_RS10810	ENOG4107UH5	it plays a direct role in the translocation of protons across the membrane (By similarity)
HFP48_RS10815	ENOG4105ZA1	atp synthase
HFP48_RS10820	ENOG4107Z0K	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
HFP48_RS10825	ENOG4108SBS	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HFP48_RS10830	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
HFP48_RS10835	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
HFP48_RS10840	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
HFP48_RS10845	ENOG410825K	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
HFP48_RS10860	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HFP48_RS10885	ENOG4105CYV	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures (By similarity)
HFP48_RS10905	ENOG4105CHU	acetyl-coa acetyltransferase
HFP48_RS10910	ENOG4105EYF	MMPL domain protein
HFP48_RS10925	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
HFP48_RS10930	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
HFP48_RS10935	ENOG4108IUN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
HFP48_RS10945	ENOG4105CPT	Alpha beta hydrolase
HFP48_RS10985	ENOG4108RWI	nicotinamidase
HFP48_RS10990	ENOG4107RKP	Nicotinate phosphoribosyltransferase
HFP48_RS10995	ENOG4105KEN	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
HFP48_RS11000	ENOG4108Q7D	Domain of unknown function (DUF2017)
HFP48_RS11020	ENOG4108RQ5	Beta-lactamase domain-containing protein
HFP48_RS11025	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
HFP48_RS11030	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HFP48_RS11085	ENOG4105FF0	ErfK YbiS YcfS YnhG
HFP48_RS11120	ENOG4107UBC	ErfK ybiS ycfS ynhG family protein
HFP48_RS11135	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
HFP48_RS11140	ENOG4105D7A	ATP-binding protein
HFP48_RS11145	ENOG4107FW0	short-chain dehydrogenase reductase
HFP48_RS11150	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HFP48_RS11185	ENOG4105EJ2	Transcriptional regulator
HFP48_RS11205	ENOG4107R37	Glutamate dehydrogenase
HFP48_RS11215	ENOG4105DAA	L-lactate
HFP48_RS11220	ENOG4105CQB	FAD linked oxidase domain protein
HFP48_RS11260	ENOG4105CHR	reductase
HFP48_RS11305	ENOG4105E4J	Cytochrome c oxidase caa3-type, assembly factor ctag-related protein
HFP48_RS11340	ENOG4105C7I	Dehydrogenase
HFP48_RS11345	ENOG4108TGP	Thioesterase superfamily protein
HFP48_RS11360	ENOG4105CG3	alpha amylase, catalytic region
HFP48_RS11380	ENOG4109057	
HFP48_RS11395	ENOG4105MC2	DSBA oxidoreductase
HFP48_RS11430	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
HFP48_RS11435	ENOG41080RH	Thioredoxin
HFP48_RS11465	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
HFP48_RS11470	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HFP48_RS11475	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HFP48_RS11480	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
HFP48_RS11485	ENOG4105CSH	Transporter
HFP48_RS11490	ENOG4108W9H	Tetr family transcriptional regulator
HFP48_RS11495	ENOG4107S9B	Shikimate dehydrogenase
HFP48_RS11510	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
HFP48_RS11530	ENOG4105CBC	glutamate synthase
HFP48_RS11535	ENOG4105M90	Glutamate synthase alpha subunit domain protein
HFP48_RS11540	ENOG4105EYU	Glutamine amido-transferase
HFP48_RS11560	ENOG4105E3J	oxidoreductase
HFP48_RS11585	ENOG4105PP6	Membrane
HFP48_RS11625	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
HFP48_RS11635	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
HFP48_RS11640	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HFP48_RS11650	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
HFP48_RS11655	ENOG4105C03	ribonuclease
HFP48_RS11660	ENOG410826X	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
HFP48_RS11665	ENOG4105K46	50S ribosomal protein l27
HFP48_RS11670	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HFP48_RS11675	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
HFP48_RS11685	ENOG4105F9U	Dehydrogenase
HFP48_RS11690	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
HFP48_RS11695	ENOG4108JPW	Aminotransferase
HFP48_RS11700	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
HFP48_RS11730	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
HFP48_RS11735	ENOG4105CGU	Enoyl-CoA hydratase
HFP48_RS11740	ENOG4105VB9	50S ribosomal protein l28
HFP48_RS11745	ENOG4105DP4	dak2 domain fusion protein ylov
HFP48_RS11750	ENOG4105CB5	ATP-dependent DNA helicase recG
HFP48_RS11755	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
HFP48_RS11760	ENOG4106H78	methyltransferase
HFP48_RS11765	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
HFP48_RS11785	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
HFP48_RS11790	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
HFP48_RS11800	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
HFP48_RS11830	ENOG4105CJ1	ABC, transporter
HFP48_RS11845	ENOG4105CIG	ABC transporter
HFP48_RS11850	ENOG4108X07	Tetr family transcriptional regulator
HFP48_RS11860	ENOG4105RM9	Protocatechuate 3,4-dioxygenase alpha
HFP48_RS11865	ENOG4105EU7	Protocatechuate 3,4-dioxygenase, beta
HFP48_RS11870	ENOG4105DDW	LysR family Transcriptional regulator
HFP48_RS11885	ENOG4108375	Acylphosphatase (EC 3.6.1.7)
HFP48_RS11910	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
HFP48_RS11930	ENOG4105K5M	30s ribosomal protein S16
HFP48_RS11940	ENOG4107XUM	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
HFP48_RS11945	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
HFP48_RS11965	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
HFP48_RS11970	ENOG4107QYR	Signal peptidase i
HFP48_RS11975	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HFP48_RS11985	ENOG41080R2	UPF0102 protein
HFP48_RS12010	ENOG4105C2C	drug resistance transporter, Bcr CflA
HFP48_RS12015	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HFP48_RS12030	ENOG4105CE9	30S ribosomal protein S2
HFP48_RS12035	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
HFP48_RS12040	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
HFP48_RS12045	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
HFP48_RS12050	ENOG4105KNE	Phosphatidate cytidylyltransferase
HFP48_RS12060	ENOG4105CI0	Citrate lyase
HFP48_RS12070	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HFP48_RS12080	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
HFP48_RS12090	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
HFP48_RS12100	ENOG4105CJN	penicillin-binding protein
HFP48_RS12135	ENOG4105DWT	malate dehydrogenase (quinone)
HFP48_RS12140	ENOG4105CEY	Amp-dependent synthetase and ligase
HFP48_RS12145	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HFP48_RS12160	ENOG4107XFJ	UPF0246 protein
HFP48_RS12165	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
HFP48_RS12185	ENOG4107Z1I	Required for maturation of 30S ribosomal subunits (By similarity)
HFP48_RS12210	ENOG4107ZPY	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
HFP48_RS12215	ENOG4105SFS	phosphoesterase RecJ domain protein
HFP48_RS12235	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
HFP48_RS12255	ENOG4105DSE	periplasmic solute binding protein
HFP48_RS12270	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
HFP48_RS12275	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
HFP48_RS12305	ENOG4108IUE	nitrate reductase beta subunit
HFP48_RS12320	ENOG4105C1V	Peptidase, M16
HFP48_RS12325	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
HFP48_RS12350	ENOG4107SMJ	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
HFP48_RS12360	ENOG4105CN5	Metallo-Beta-Lactamase
HFP48_RS12370	ENOG4107QZI	cell division protein FtsK
HFP48_RS12395	ENOG4105CEV	competence damage-inducible protein
HFP48_RS12400	ENOG4105WBV	Transcriptional regulator
HFP48_RS12415	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
HFP48_RS12420	ENOG4108JJB	ABC transporter
HFP48_RS12425	ENOG4107ZYJ	bioY protein
HFP48_RS12435	ENOG4105FF5	Membrane
HFP48_RS12440	ENOG4108SEA	Esterase
HFP48_RS12490	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
HFP48_RS12495	ENOG4105KC9	Modulates RecA activity (By similarity)
HFP48_RS12500	ENOG4105DRP	amino acid AbC transporter
HFP48_RS12505	ENOG4108Q1T	ABC transporter
HFP48_RS12510	ENOG4107UBR	Extracellular solute-binding protein family 3
HFP48_RS12515	ENOG4105CDA	abc transporter atp-binding protein
HFP48_RS12520	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HFP48_RS12530	ENOG4105C99	atpase involved in dna repair
HFP48_RS12540	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
HFP48_RS12545	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
HFP48_RS12550	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HFP48_RS12565	ENOG4105DM4	PTS System
HFP48_RS12575	ENOG4105E98	transcriptional regulator DeoR family
HFP48_RS12580	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
HFP48_RS12585	ENOG4105C2W	permease
HFP48_RS12590	ENOG4105C1G	acyl-Coa dehydrogenase
HFP48_RS12595	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HFP48_RS12605	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
HFP48_RS12610	ENOG4105CQ7	ATP-dependent helicase
HFP48_RS12615	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
HFP48_RS12650	ENOG4105C5Q	Transcriptional regulator
HFP48_RS12655	ENOG4105CD3	dihydroorotase
HFP48_RS12660	ENOG4105CQR	helicase
HFP48_RS12695	ENOG4105DGU	Histone deacetylase
HFP48_RS12700	ENOG410870F	Cyclic nucleotide-binding protein
HFP48_RS12710	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
HFP48_RS12750	ENOG4107S91	Sodium hydrogen exchanger
HFP48_RS12785	ENOG4107ZFB	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
HFP48_RS12815	ENOG4107VEG	TrkA-N domain protein
HFP48_RS12820	ENOG4105C0X	amino acid
HFP48_RS12825	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
HFP48_RS12830	ENOG41067TZ	transcriptional regulator, MarR family
HFP48_RS12835	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HFP48_RS12850	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
HFP48_RS12860	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HFP48_RS12865	ENOG4105CHU	acetyl-coa acetyltransferase
HFP48_RS12890	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
HFP48_RS12900	ENOG4107JTW	chlorite dismutase
HFP48_RS12905	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
HFP48_RS12910	ENOG4108J2R	molybdopterin oxidoreductase
HFP48_RS12925	ENOG4105E0X	reductase
HFP48_RS12930	ENOG4108P2G	integral membrane protein
HFP48_RS12990	ENOG4105C22	threonyL-tRNA synthetase
HFP48_RS13010	ENOG4105E2K	Glycosyl transferase (Group 1
HFP48_RS13015	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
HFP48_RS13020	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
HFP48_RS13030	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
HFP48_RS13035	ENOG4105CDY	transcriptional regulatory protein
HFP48_RS13040	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
HFP48_RS13045	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
HFP48_RS13050	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
HFP48_RS13065	ENOG4107RTU	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HFP48_RS13070	ENOG4108NY6	Extracellular solute-binding protein, family 5
HFP48_RS13075	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
HFP48_RS13080	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HFP48_RS13100	ENOG4108JJA	ABC, transporter
HFP48_RS13110	ENOG4108ZR3	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity)
HFP48_RS13125	ENOG4105CUT	histidyl-tRNA synthetase
HFP48_RS13145	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HFP48_RS13160	ENOG4105DVC	DnaJ domain protein
HFP48_RS13165	ENOG4107RM1	amidohydrolase
HFP48_RS13175	ENOG4105CAQ	asparagine synthetase
HFP48_RS13180	ENOG4105C0I	Conserved Protein
HFP48_RS13215	ENOG4107R7A	Allophanate hydrolase subunit 2
HFP48_RS13230	ENOG4105C85	amino acid
HFP48_RS13240	ENOG4105WN5	stage II sporulation protein
HFP48_RS13250	ENOG4107SGM	protein serine threonine phosphatase
HFP48_RS13260	ENOG4105F95	Monooxygenase
HFP48_RS13290	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HFP48_RS13350	ENOG4105C9M	aspartyl-trna synthetase
HFP48_RS13395	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HFP48_RS13400	ENOG41080G3	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
HFP48_RS13410	ENOG4105E2X	shikimate dehydrogenase
HFP48_RS13430	ENOG4105CHP	RNA polymerase
HFP48_RS13445	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
HFP48_RS13450	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HFP48_RS13455	ENOG4105D49	3-dehydroquinate synthase
HFP48_RS13470	ENOG4105MHT	Transcriptional regulator, ARSR family
HFP48_RS13495	ENOG4105DC7	peptidase M24
HFP48_RS13500	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HFP48_RS13505	ENOG410803B	Involved in the transcription termination process (By similarity)
HFP48_RS13510	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
HFP48_RS13515	ENOG4105CXT	aspartate transcarbamylase
HFP48_RS13530	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
HFP48_RS13540	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
HFP48_RS13550	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
HFP48_RS13555	ENOG4105MTQ	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
HFP48_RS13565	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
HFP48_RS13585	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
HFP48_RS13600	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
HFP48_RS13620	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
HFP48_RS13625	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
HFP48_RS13635	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
HFP48_RS13640	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
HFP48_RS13650	ENOG4105CIE	May be required for sporulation (By similarity)
HFP48_RS13655	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HFP48_RS13660	ENOG4105BZA	Phosphoglycerate kinase
HFP48_RS13665	ENOG4105CP7	Triose-phosphate isomerase
HFP48_RS13675	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
HFP48_RS13685	ENOG4105EUZ	Beta-lactamase domain protein
HFP48_RS13720	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HFP48_RS13730	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
HFP48_RS13735	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
HFP48_RS13755	ENOG4105CJ1	ABC, transporter
HFP48_RS13760	ENOG4107JC6	Membrane
HFP48_RS13780	ENOG4105C3K	feS assembly ATPase SufC
HFP48_RS13790	ENOG4108UNV	SUF system FeS assembly protein, NifU family
HFP48_RS13805	ENOG4105FDF	Could be involved in DNA repair (By similarity)
HFP48_RS13830	ENOG4108Q5F	Tetr family transcriptional regulator
HFP48_RS13835	ENOG4107QM5	aconitate hydratase
HFP48_RS13845	ENOG4105ZXU	NLP P60 protein
HFP48_RS13850	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HFP48_RS13860	ENOG4107QVM	von Willebrand factor, type A
HFP48_RS13865	ENOG4105CHR	reductase
HFP48_RS13875	ENOG4107QME	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
HFP48_RS13930	ENOG4108MXC	l-carnitine dehydratase bile acid-inducible protein F
HFP48_RS13935	ENOG410635A	Membrane
HFP48_RS13940	ENOG4105EG6	Saccharopine dehydrogenase
HFP48_RS13975	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HFP48_RS13985	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
HFP48_RS14005	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
HFP48_RS14010	ENOG4105EHG	Permease protein
HFP48_RS14020	ENOG4105EWN	Heme oxygenase
HFP48_RS14025	ENOG4105CPC	Aldo Keto reductase
HFP48_RS14030	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
HFP48_RS14050	ENOG4105C8N	cysteinyl-tRNA synthetase
HFP48_RS14100	ENOG4107QRT	dEAD DEAH box helicase
HFP48_RS14160	ENOG4105KH3	nitrite reductase (NAD(P)h) small subunit
HFP48_RS14165	ENOG4108IFG	nitrite reductase, (NAD(P)H)
HFP48_RS14170	ENOG4107QNK	)-transporter
HFP48_RS14180	ENOG4105C3R	Methionine synthase
HFP48_RS14185	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
HFP48_RS14190	ENOG4105C72	UPF0176 protein
HFP48_RS14195	ENOG4105D3G	Pseudouridine synthase
HFP48_RS14200	ENOG4105M0N	phosphoribosyl-ATP pyrophosphatase
HFP48_RS14205	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
HFP48_RS14235	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
HFP48_RS14245	ENOG4105E5F	proteasome
HFP48_RS14260	ENOG4105F7N	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
HFP48_RS14270	ENOG4105DVV	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine (By similarity)
HFP48_RS14280	ENOG4107TMB	Transcriptional regulator
HFP48_RS14285	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
HFP48_RS14320	ENOG4108RG3	short-chain dehydrogenase reductase
HFP48_RS14325	ENOG4107QN2	dihydrolipoyl dehydrogenase
HFP48_RS14350	ENOG4105ETE	Transcriptional regulator (LacI family
HFP48_RS14370	ENOG4105CG3	alpha amylase, catalytic region
HFP48_RS14395	ENOG4105CD3	dihydroorotase
HFP48_RS14405	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
HFP48_RS14440	ENOG4105Q70	
HFP48_RS14460	ENOG41062IE	glyoxalase bleomycin resistance protein dioxygenase
HFP48_RS14475	ENOG4105CHU	acetyl-coa acetyltransferase
HFP48_RS14480	ENOG4108Z4X	TRANSCRIPTIONal
HFP48_RS14485	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HFP48_RS14490	ENOG4105CEP	NADH dehydrogenase
HFP48_RS14505	ENOG4105DQ5	transport system permease protein
HFP48_RS14510	ENOG4105TVJ	transport system, permease
HFP48_RS14515	ENOG4105E0A	ABC, transporter
HFP48_RS14530	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
HFP48_RS14535	ENOG4105PP6	Membrane
HFP48_RS14545	ENOG4105C37	(CBS) domain
HFP48_RS14550	ENOG4107UAX	integral membrane protein
HFP48_RS14565	ENOG4105DNP	FAD linked oxidase domain protein
HFP48_RS14580	ENOG4107QP3	malate synthase g
HFP48_RS14590	ENOG4105DIN	metallophosphoesterase
HFP48_RS14615	ENOG4108UW8	fha domain-containing protein
HFP48_RS14620	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
HFP48_RS14645	ENOG4105M6F	mutator MutT protein
HFP48_RS14675	ENOG4105C0A	alcohol dehydrogenase
HFP48_RS14685	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
HFP48_RS14690	ENOG4105CAT	Cytidine monophosphate kinase
HFP48_RS14700	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
HFP48_RS14725	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
HFP48_RS14745	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
HFP48_RS14760	ENOG4105DSU	hydrolase
HFP48_RS14785	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
HFP48_RS14790	ENOG4108VX5	3-methyladenine DNA glycosylase
HFP48_RS14805	ENOG4105CH7	arginosuccinase
HFP48_RS14810	ENOG4105CDH	Citrulline--aspartate ligase
HFP48_RS14815	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
HFP48_RS14820	ENOG4105DBV	ornithine carbamoyltransferase
HFP48_RS14830	ENOG4105CAS	nag kinase
HFP48_RS14835	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
HFP48_RS14840	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
HFP48_RS14850	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
HFP48_RS14855	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
HFP48_RS14865	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
HFP48_RS14870	ENOG41084BS	50S ribosomal protein L35
HFP48_RS14915	ENOG4105C26	Dehydrogenase
HFP48_RS14925	ENOG4108YV4	Universal stress protein
HFP48_RS14935	ENOG4107S9D	Alpha beta hydrolase
HFP48_RS14980	ENOG4105DGI	Alkaline phosphatase
HFP48_RS14990	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HFP48_RS15005	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HFP48_RS15010	ENOG4105DF2	NADH dehydrogenase subunit j
HFP48_RS15015	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
HFP48_RS15020	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
HFP48_RS15025	ENOG4108IEH	NADH dehydrogenase subunit g
HFP48_RS15040	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HFP48_RS15045	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HFP48_RS15050	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HFP48_RS15065	ENOG4105CHH	sulfate transporter
HFP48_RS15120	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
HFP48_RS15130	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HFP48_RS15135	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HFP48_RS15145	ENOG4107RCI	amp-dependent synthetase and ligase
HFP48_RS15150	ENOG4108JEH	abc transporter atp-binding protein
HFP48_RS15160	ENOG4106PMH	Extracellular solute-binding protein family 3
HFP48_RS15170	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HFP48_RS15180	ENOG4105ECQ	AraC Family Transcriptional Regulator
HFP48_RS15185	ENOG41080RH	Thioredoxin
HFP48_RS15195	ENOG4105CNN	ABC, transporter
HFP48_RS15200	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
HFP48_RS15205	ENOG4105C0Z	ABC transporter
HFP48_RS15210	ENOG4108IV0	ABC, transporter
HFP48_RS15245	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
HFP48_RS15280	ENOG4107R0V	Pyruvate dehydrogenase
HFP48_RS15300	ENOG4105CB2	alcohol dehydrogenase
HFP48_RS15310	ENOG4105C29	acyl-CoA thioesterase
HFP48_RS15320	ENOG4105KNI	merR family transcriptional Regulator
HFP48_RS15325	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
HFP48_RS15350	ENOG4105CBC	glutamate synthase
HFP48_RS15360	ENOG4107V6M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
HFP48_RS15365	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
HFP48_RS15375	ENOG4105DK0	Indole-3-glycerol phosphate synthase
HFP48_RS15385	ENOG4105CRQ	synthase (Component I)
HFP48_RS15395	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
HFP48_RS15425	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
HFP48_RS15430	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
HFP48_RS15435	ENOG4108MWI	inositol mono-phosphatase
HFP48_RS15440	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
HFP48_RS15450	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
HFP48_RS15465	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
HFP48_RS15470	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HFP48_RS15475	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
HFP48_RS15485	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
HFP48_RS15500	ENOG4105CS2	ec 3.2.1.21
HFP48_RS15505	ENOG410829K	Lysine exporter protein (Lyse ygga)
HFP48_RS15530	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
HFP48_RS15555	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
HFP48_RS15570	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
HFP48_RS15610	ENOG4107WHG	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
HFP48_RS15615	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HFP48_RS15620	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
HFP48_RS15690	ENOG4105K5B	UPF0225 protein
HFP48_RS15725	ENOG4105C57	major facilitator superfamily
HFP48_RS15745	ENOG4105C7K	acetolactate synthase
HFP48_RS15760	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HFP48_RS15765	ENOG4105JZI	cytochrome P450
HFP48_RS15770	ENOG4107R13	MMPL domain protein
HFP48_RS15780	ENOG4105PFC	Transcriptional regulator
HFP48_RS15845	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
HFP48_RS15855	ENOG4107VQS	DivIVA family
HFP48_RS15865	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
HFP48_RS15880	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
HFP48_RS15885	ENOG4105ME9	cell division protein FtsQ
HFP48_RS15890	ENOG4105DFU	Cell wall formation (By similarity)
HFP48_RS15895	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
HFP48_RS15905	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
HFP48_RS15910	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
HFP48_RS15925	ENOG4105CJN	penicillin-binding protein
HFP48_RS15935	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
HFP48_RS15940	ENOG4108V6E	Cell division protein mraZ
HFP48_RS15970	ENOG4105R14	(LipO)protein
HFP48_RS15975	ENOG41076QQ	Glycosyl transferase, family 2
HFP48_RS15995	ENOG41090CE	integral membrane protein
HFP48_RS16005	ENOG4105KYH	transcriptional regulatory protein
HFP48_RS16015	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
HFP48_RS16025	ENOG4105E9Q	Acyl-transferase
HFP48_RS16030	ENOG4105DKQ	ROK family
HFP48_RS16040	ENOG4105D0U	Arsenite-activated ATPase (ArsA)
HFP48_RS16055	ENOG4105JNK	Glycosyl transferase (Group 1
HFP48_RS16070	ENOG4105K4H	Nlp p60 protein
HFP48_RS16085	ENOG4108I0Q	anthranilate phosphoribosyltransferase
HFP48_RS16095	ENOG4105CCU	oxidase (Subunit III)
HFP48_RS16115	ENOG4108ZRS	Part of cytochrome c oxidase, its function is
HFP48_RS16120	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
HFP48_RS16130	ENOG4107T4Z	adenosine kinase
HFP48_RS16150	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
HFP48_RS16155	ENOG410813T	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
HFP48_RS16160	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HFP48_RS16165	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
HFP48_RS16170	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HFP48_RS16185	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
HFP48_RS16190	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
HFP48_RS16205	ENOG4105C5F	glutamine synthetase
HFP48_RS16225	ENOG4105CUB	amino acid
HFP48_RS16250	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
HFP48_RS16255	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
HFP48_RS16260	ENOG4105C5F	glutamine synthetase
HFP48_RS16270	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
HFP48_RS16290	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
HFP48_RS16400	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
HFP48_RS16415	ENOG41082KT	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HFP48_RS16425	ENOG4106H22	propionyl-CoA carboxylase
HFP48_RS16435	ENOG4107S1E	Beta-lactamase
HFP48_RS16450	ENOG4105CY0	Metallo-Beta-Lactamase
HFP48_RS16460	ENOG410904A	RNA polymerase
HFP48_RS16470	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
HFP48_RS16495	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
HFP48_RS16510	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
HFP48_RS16535	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
HFP48_RS16540	ENOG4106DBE	Involved in DNA repair and RecF pathway recombination (By similarity)
HFP48_RS16550	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
HFP48_RS16575	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
HFP48_RS16585	ENOG4107VNR	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
HFP48_RS16600	ENOG4105C57	major facilitator superfamily
HFP48_RS16620	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HFP48_RS16625	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
HFP48_RS16645	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
HFP48_RS16665	ENOG4108YV4	Universal stress protein
HFP48_RS16670	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
HFP48_RS16680	ENOG4105BZP	glycoside hydrolase 15-related
HFP48_RS16685	ENOG4105EA8	2-Nitropropane dioxygenase
HFP48_RS16690	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
HFP48_RS16700	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
HFP48_RS16720	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
HFP48_RS16750	ENOG4105CVJ	phosphoglycerate mutase
HFP48_RS16755	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
HFP48_RS16760	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
HFP48_RS16770	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HFP48_RS16775	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
HFP48_RS16780	ENOG4105CPF	Cell wall formation (By similarity)
HFP48_RS16785	ENOG4105C28	cystathionine
HFP48_RS16790	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
HFP48_RS16800	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
HFP48_RS16815	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HFP48_RS16820	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HFP48_RS16825	ENOG4107HP6	Transcriptional regulator
HFP48_RS16855	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
HFP48_RS16860	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
HFP48_RS16865	ENOG4105E5T	Major Facilitator Superfamily
HFP48_RS16870	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HFP48_RS16885	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
HFP48_RS16890	ENOG4108ZP8	Acetolactate synthase small subunit
HFP48_RS16905	ENOG4105C01	Dihydroxy-acid dehydratase
HFP48_RS16930	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HFP48_RS16940	ENOG4105WH1	Two component transcriptional regulator luxr family
HFP48_RS16945	ENOG4108ZGX	Histidine kinase
HFP48_RS16960	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HFP48_RS16965	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HFP48_RS16975	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
HFP48_RS16980	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
HFP48_RS16990	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
HFP48_RS17010	ENOG4105C10	Electron transfer flavoprotein
HFP48_RS17020	ENOG4108KQJ	Type 11 methyltransferase
HFP48_RS17040	ENOG4105EVB	acetyltransferase
HFP48_RS17045	ENOG4108V0V	Pyrrolo-quinoline quinone
HFP48_RS17050	ENOG41090KQ	Glyoxalase Bleomycin resistance protein (Dioxygenase
HFP48_RS17055	ENOG4105NPE	arsR family transcriptional regulator
HFP48_RS17065	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HFP48_RS17080	ENOG4105DKW	ABC transporter
HFP48_RS17095	ENOG4105EAC	phosphoserine phosphatase
HFP48_RS17100	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HFP48_RS17130	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
HFP48_RS17140	ENOG4105C7W	Xanthine dehydrogenase
HFP48_RS17145	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
HFP48_RS17150	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
HFP48_RS17160	ENOG4108SGK	Tetr family transcriptional regulator
HFP48_RS17180	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
HFP48_RS17190	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HFP48_RS17200	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HFP48_RS17205	ENOG4108ZAF	Molybdopterin
HFP48_RS17210	ENOG4105C1J	atp-dependent rna helicase
HFP48_RS17215	ENOG4105CKI	cobalamin synthesis protein
HFP48_RS17235	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
HFP48_RS17240	ENOG4105WH1	Two component transcriptional regulator luxr family
HFP48_RS17265	ENOG4105Q56	cytochrome P450
HFP48_RS17270	ENOG4107HP6	Transcriptional regulator
HFP48_RS17315	ENOG41084I6	Protein CrcB homolog
HFP48_RS17335	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
HFP48_RS17340	ENOG4107RYD	Part of the ABC transporter FtsEX involved in cellular division (By similarity)
HFP48_RS17345	ENOG4105CAK	Cell division ATP-binding protein ftsE
HFP48_RS17355	ENOG4105D8X	mechanosensitive ion channel
HFP48_RS17360	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
HFP48_RS17365	ENOG4107TK4	histidinol-phosphate phosphatase
HFP48_RS17375	ENOG4105C1G	acyl-Coa dehydrogenase
HFP48_RS17395	ENOG4105DJZ	UPF0182 protein
HFP48_RS17405	ENOG41063PX	domain protein
HFP48_RS17430	ENOG4105WBQ	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
HFP48_RS17445	ENOG4105E1F	short-chain dehydrogenase reductase
HFP48_RS17490	ENOG4108YIQ	Alpha beta hydrolase
HFP48_RS17495	ENOG41080UX	Methyltransferase
HFP48_RS17505	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
HFP48_RS17510	ENOG4105ME7	Membrane
HFP48_RS17530	ENOG4107QZF	nitrite reductase NADPH large subunit
HFP48_RS17545	ENOG4105JXH	GntR family transcriptional regulator
HFP48_RS17580	ENOG4105C1J	atp-dependent rna helicase
HFP48_RS17605	ENOG4107TE5	Lipid kinase
HFP48_RS17620	ENOG4106063	Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit
HFP48_RS17635	ENOG4108Z66	YbaK ebsC protein
HFP48_RS17645	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
HFP48_RS17650	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
HFP48_RS17690	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HFP48_RS17695	ENOG4108S7Q	sigma 54 modulation protein ribosomal protein S30ea
HFP48_RS17705	ENOG4108MKR	lipoprotein lpqb
HFP48_RS17710	ENOG4105BZU	Histidine kinase
HFP48_RS17715	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HFP48_RS17725	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
HFP48_RS17735	ENOG4105CUB	amino acid
HFP48_RS17740	ENOG4105EIP	mannose-6-phosphate isomerase
HFP48_RS17750	ENOG4107QKV	phosphomannomutase
HFP48_RS17765	ENOG4105K51	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
HFP48_RS17775	ENOG41088YA	Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives (By similarity)
HFP48_RS17785	ENOG41090WU	lipolytic protein G-D-S-L family
HFP48_RS17800	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
HFP48_RS17805	ENOG4107TB5	TRANSCRIPTIONal
HFP48_RS17820	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HFP48_RS17825	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HFP48_RS17830	ENOG4105WH1	Two component transcriptional regulator luxr family
HFP48_RS17835	ENOG4105BZU	Histidine kinase
HFP48_RS17845	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
HFP48_RS17855	ENOG41065SU	Two-component system sensor kinase
HFP48_RS17860	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HFP48_RS17870	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
HFP48_RS17875	ENOG4105D8K	carboxyl transferase
HFP48_RS17885	ENOG4107WR6	Maf-like protein
HFP48_RS17890	ENOG41089UC	methyltransferase, type 11
HFP48_RS17920	ENOG4108JIK	carboxylase
HFP48_RS17960	ENOG4108XM1	transcriptional regulator AsnC family
HFP48_RS17965	ENOG4105C26	Dehydrogenase
HFP48_RS17990	ENOG4105CEY	Amp-dependent synthetase and ligase
HFP48_RS17995	ENOG4105CQB	FAD linked oxidase domain protein
HFP48_RS18005	ENOG4107QRT	dEAD DEAH box helicase
HFP48_RS18010	ENOG4108S0J	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'- phosphates (By similarity)
HFP48_RS18035	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
HFP48_RS18040	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HFP48_RS18065	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HFP48_RS18075	ENOG4107QKW	extracellular solute-binding protein family 1
HFP48_RS18080	ENOG4107RM1	amidohydrolase
HFP48_RS18100	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
HFP48_RS18110	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
HFP48_RS18115	ENOG4105E90	ABC transporter
HFP48_RS18120	ENOG4108IJ8	ABC transporter
HFP48_RS18125	ENOG4105E90	ABC transporter
HFP48_RS18130	ENOG4107SI7	Substrate-binding region of abc-type glycine betaine transport system
HFP48_RS18150	ENOG4105K4H	Nlp p60 protein
HFP48_RS18180	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
HFP48_RS18215	ENOG4105DQ4	alcohol dehydrogenase
HFP48_RS18220	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
HFP48_RS18225	ENOG4108IND	Tetr family transcriptional regulator
HFP48_RS18230	ENOG4107H3J	ribonuclease
HFP48_RS18235	ENOG4105C31	Tryptophanyl-tRNA synthetase
HFP48_RS18240	ENOG4105CGK	Exodeoxyribonuclease III
HFP48_RS18250	ENOG4108IQK	o-acetylhomoserine
HFP48_RS18255	ENOG4105DWV	Homoserine O-trans-acetylase
HFP48_RS18265	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
HFP48_RS18270	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
HFP48_RS18275	ENOG4108ZEY	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
HFP48_RS18280	ENOG4105K6V	RNA polymerase
HFP48_RS18305	ENOG4105C0B	DNA polymerase III (alpha subunit)
HFP48_RS18310	ENOG4108KPJ	rna polymerase sigma factor
HFP48_RS18325	ENOG41082SX	arsR family transcriptional regulator
HFP48_RS18330	ENOG41064MX	Tetr family transcriptional regulator
HFP48_RS18340	ENOG4107TZ2	Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity)
HFP48_RS18345	ENOG4105CIG	ABC transporter
HFP48_RS18350	ENOG4105DIM	ABC transporter
HFP48_RS18360	ENOG4105PDP	Short chain dehydrogenase
HFP48_RS18395	ENOG4108EMS	branched-chain alpha-keto acid dehydrogenase subunit E2
HFP48_RS18415	ENOG4108Z6Z	Transcriptional regulator
HFP48_RS18430	ENOG4105FM1	phage shock protein C
HFP48_RS18440	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HFP48_RS18450	ENOG4107QVP	Dehydrogenase
HFP48_RS18480	ENOG4105KIU	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
HFP48_RS18485	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
HFP48_RS18500	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HFP48_RS18505	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
HFP48_RS18520	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
HFP48_RS18525	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HFP48_RS18535	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HFP48_RS18560	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
HFP48_RS18565	ENOG4108UJD	30S ribosomal protein S9
HFP48_RS18570	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
HFP48_RS18590	ENOG4105EC2	ftsk spoIIIe
HFP48_RS18600	ENOG41090GG	peptidase S8 and S53, subtilisin, kexin, sedolisin
HFP48_RS18625	ENOG4105C1G	acyl-Coa dehydrogenase
HFP48_RS18640	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
HFP48_RS18645	ENOG4108ZT0	50S ribosomal protein l17
HFP48_RS18650	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HFP48_RS18655	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
HFP48_RS18660	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
HFP48_RS18665	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HFP48_RS18670	ENOG41067V7	50S ribosomal protein L36
HFP48_RS18675	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
HFP48_RS18680	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
HFP48_RS18690	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
HFP48_RS18700	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
HFP48_RS18705	ENOG410849U	50S ribosomal protein L30
HFP48_RS18710	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
HFP48_RS18715	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
HFP48_RS18720	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
HFP48_RS18725	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
HFP48_RS18730	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
HFP48_RS18735	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HFP48_RS18740	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
HFP48_RS18745	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
HFP48_RS18750	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
HFP48_RS18760	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
HFP48_RS18765	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
HFP48_RS18775	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
HFP48_RS18780	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HFP48_RS18785	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
HFP48_RS18790	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
HFP48_RS18795	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
HFP48_RS18805	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HFP48_RS18845	ENOG4105CEY	Amp-dependent synthetase and ligase
HFP48_RS18855	ENOG4105CEY	Amp-dependent synthetase and ligase
HFP48_RS18875	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HFP48_RS18895	ENOG4105C1G	acyl-Coa dehydrogenase
HFP48_RS18905	ENOG4107QX3	carboxylase
HFP48_RS18925	ENOG4105C26	Dehydrogenase
HFP48_RS18935	ENOG4105CEY	Amp-dependent synthetase and ligase
HFP48_RS18940	ENOG4105CSH	Transporter
HFP48_RS18955	ENOG4107FQ9	ethanolamine ammonia-lyase
HFP48_RS18960	ENOG4105CPD	ethanolamine ammonia-lyase
HFP48_RS18965	ENOG4105CUB	amino acid
HFP48_RS18975	ENOG4105C26	Dehydrogenase
HFP48_RS18980	ENOG4107RR1	TRANSCRIPTIONal
HFP48_RS18985	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
HFP48_RS18990	ENOG4106BQ7	Glycosyl Transferase
HFP48_RS19035	ENOG4105GRZ	Ycii-related protein
HFP48_RS19040	ENOG4105CHP	RNA polymerase
HFP48_RS19045	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
HFP48_RS19060	ENOG4105XYF	acetyltransferase
HFP48_RS19090	ENOG4105DKK	Benzoate
HFP48_RS19095	ENOG4105KD7	acetyltransferase
HFP48_RS19100	ENOG4108ESY	Metal dependent phosphohydrolase
HFP48_RS19115	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HFP48_RS19125	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HFP48_RS19140	ENOG4105XDV	
HFP48_RS19160	ENOG4105DIM	ABC transporter
HFP48_RS19165	ENOG4105CIG	ABC transporter
HFP48_RS19175	ENOG4105KVH	Transcriptional regulator
HFP48_RS19190	ENOG4105WH1	Two component transcriptional regulator luxr family
HFP48_RS19200	ENOG4105C0A	alcohol dehydrogenase
HFP48_RS19220	ENOG4106JDQ	ATP-dependent Clp protease, Hsp 100, ATP-binding subunit ClpB
HFP48_RS19250	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
HFP48_RS19260	ENOG4105VBF	alkaline shock protein
HFP48_RS19285	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HFP48_RS19290	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
HFP48_RS19295	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
HFP48_RS19320	ENOG4108Q5F	Tetr family transcriptional regulator
HFP48_RS19325	ENOG4105DYW	oxidoreductase
HFP48_RS19345	ENOG4107QX3	carboxylase
HFP48_RS19365	ENOG4107AQZ	Membrane
HFP48_RS19370	ENOG4105C57	major facilitator superfamily
HFP48_RS19375	ENOG4105C5Q	Transcriptional regulator
HFP48_RS19385	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HFP48_RS19390	ENOG4105JP4	Inner membrane protein yidG
HFP48_RS19395	ENOG4105VG5	Membrane
HFP48_RS19420	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HFP48_RS19445	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HFP48_RS19450	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HFP48_RS19510	ENOG41082SK	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
HFP48_RS19515	ENOG4108VZM	50s ribosomal protein L10
HFP48_RS19520	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
HFP48_RS19525	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
HFP48_RS19550	ENOG410900P	UPF0336 protein
HFP48_RS19575	ENOG4108VPT	UPF0234 protein
HFP48_RS19580	ENOG4105D0M	Protease HtpX homolog
HFP48_RS19595	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HFP48_RS19610	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
HFP48_RS19615	ENOG4105EW6	flavin reductase domain protein, FMN-binding
HFP48_RS19630	ENOG4107TCW	O-succinylbenzoate synthase
HFP48_RS19660	ENOG4108IV0	ABC, transporter
HFP48_RS19665	ENOG4105C0Z	ABC transporter
HFP48_RS19710	ENOG41082T9	Membrane
HFP48_RS19755	ENOG4105CRE	cytochrome C
HFP48_RS19765	ENOG4107QIV	Cytochrome c biogenesis protein
HFP48_RS19775	ENOG4108RH7	phosphoglycerate mutase
HFP48_RS19780	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
HFP48_RS19795	ENOG4107VWA	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity)
HFP48_RS19800	ENOG4105D8V	Glucose sorbosone dehydrogenase
HFP48_RS19810	ENOG4108Z4X	TRANSCRIPTIONal
HFP48_RS19820	ENOG4105VPX	protein, conserved in bacteria
HFP48_RS19840	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HFP48_RS19845	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
HFP48_RS19850	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
HFP48_RS19855	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
HFP48_RS19910	ENOG4105EY0	Xylose isomerase domain protein TIM barrel
HFP48_RS19915	ENOG41063NU	Membrane
HFP48_RS19930	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HFP48_RS19935	ENOG4105BZU	Histidine kinase
HFP48_RS19940	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HFP48_RS19950	ENOG4107SCK	Monooxygenase
HFP48_RS19955	ENOG4105CEY	Amp-dependent synthetase and ligase
HFP48_RS19970	ENOG4105MS9	Resuscitation-promoting factor
HFP48_RS19975	ENOG4108YZJ	Pfam:DUF2596
HFP48_RS19980	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HFP48_RS20005	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
HFP48_RS20045	ENOG4107R4N	Cell wall formation (By similarity)
HFP48_RS20075	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
HFP48_RS20100	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
HFP48_RS20110	ENOG4105CIY	formyltetrahydrofolate deformylase
HFP48_RS20120	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
HFP48_RS20130	ENOG4105TT9	Protein of unknown function (DUF2516)
HFP48_RS20135	ENOG4105V9F	hemagglutinin
HFP48_RS20145	ENOG4106BRA	Membrane
HFP48_RS20160	ENOG4105CSR	polyphosphate kinase 2
HFP48_RS20175	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HFP48_RS20200	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HFP48_RS20230	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
HFP48_RS20245	ENOG4105DQV	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
HFP48_RS20250	ENOG4108Z0Z	intracellular protease Pfpi family
HFP48_RS20315	ENOG4105DQ4	alcohol dehydrogenase
HFP48_RS20320	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
HFP48_RS20335	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
HFP48_RS20355	ENOG4105C32	Amino acid ABC transporter (Permease)
HFP48_RS20365	ENOG4105C0Z	ABC transporter
HFP48_RS20370	ENOG4108IV0	ABC, transporter
HFP48_RS20375	ENOG4105DRR	Transcriptional regulator, GntR family
HFP48_RS20385	ENOG4105DRR	Transcriptional regulator, GntR family
HFP48_RS20405	ENOG4105ECR	NmrA family
HFP48_RS20410	ENOG4105KVH	Transcriptional regulator
HFP48_RS20430	ENOG4108QIU	Dehydrogenase
HFP48_RS20450	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
HFP48_RS20480	ENOG4105DHU	Bile acid
HFP48_RS20485	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
HFP48_RS20495	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
HFP48_RS20500	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
HFP48_RS20505	ENOG4105CGP	Urocanate hydratase
HFP48_RS20510	ENOG4105CI2	imidazolone-5-propionate hydrolase
HFP48_RS20515	ENOG41088SP	formiminoglutamate hydrolase
HFP48_RS20520	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
HFP48_RS20525	ENOG4105C84	Histidine ammonia-lyase
HFP48_RS20545	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
HFP48_RS20565	ENOG4105E09	nadh pyrophosphatase
HFP48_RS20570	ENOG4105D65	subunit l
HFP48_RS20575	ENOG4105MKQ	Monovalent cation H antiporter subunit C
HFP48_RS20580	ENOG4108JPZ	Monovalent cation H antiporter subunit D
HFP48_RS20605	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
HFP48_RS20610	ENOG4105H08	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HFP48_RS20625	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HFP48_RS20645	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
HFP48_RS20650	ENOG4105DWF	phosphomethylpyrimidine kinase
HFP48_RS20660	ENOG4105IIU	Aminopeptidase
HFP48_RS20670	ENOG4105CJ1	ABC, transporter
HFP48_RS20680	ENOG4108S8N	class II Aldolase
HFP48_RS20685	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HFP48_RS20690	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
HFP48_RS20705	ENOG4107Y5I	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
HFP48_RS20720	ENOG4105CT1	(ABC) transporter
HFP48_RS20735	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
HFP48_RS20745	ENOG4108QMY	dioxygenase
HFP48_RS20755	ENOG4105MXW	flavin reductase domain protein, FMN-binding
HFP48_RS20765	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
HFP48_RS20785	ENOG4107W6X	Transcriptional regulator
HFP48_RS20800	ENOG4107RID	5-oxoprolinase (ATP-hydrolyzing)
HFP48_RS20805	ENOG4105RQI	acetone carboxylase gamma subunit
HFP48_RS20810	ENOG4107SZ9	Hydantoinase oxoprolinase
HFP48_RS20840	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
HFP48_RS20845	ENOG4105EHG	Permease protein
HFP48_RS20850	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
HFP48_RS20855	ENOG4105CKW	Inner membrane protein yedI
HFP48_RS20865	ENOG4105MGE	Rhodanese domain protein
HFP48_RS20885	ENOG4107SPG	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
HFP48_RS20890	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HFP48_RS20905	ENOG410846T	CoA-transferase family III
HFP48_RS20915	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HFP48_RS20920	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HFP48_RS20925	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
HFP48_RS20950	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HFP48_RS20980	ENOG4105CTK	cobaltochelatase, cobn subunit
HFP48_RS21005	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
HFP48_RS21015	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
HFP48_RS21020	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
HFP48_RS21025	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
HFP48_RS21040	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
HFP48_RS21090	ENOG4107XFB	conserved TRANSMEMBRANE PROTEIN
HFP48_RS21095	ENOG4105CKI	cobalamin synthesis protein
HFP48_RS21115	ENOG4105CHR	reductase
HFP48_RS21130	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
HFP48_RS21150	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
HFP48_RS21165	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HFP48_RS21175	ENOG4105WH1	Two component transcriptional regulator luxr family
HFP48_RS21185	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
HFP48_RS21195	ENOG4107SN7	NLP P60 protein
HFP48_RS21275	ENOG4105CEY	Amp-dependent synthetase and ligase
HFP48_RS21280	ENOG4105ETE	Transcriptional regulator (LacI family
HFP48_RS21285	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HFP48_RS21315	ENOG4107SHJ	sulfite reductase subunit b
HFP48_RS21335	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
HFP48_RS21345	ENOG4105MXW	flavin reductase domain protein, FMN-binding
HFP48_RS21350	ENOG4105DEN	Luciferase family
HFP48_RS21355	ENOG4105KNI	merR family transcriptional Regulator
HFP48_RS21360	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HFP48_RS21365	ENOG4108093	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HFP48_RS21370	ENOG4105CFG	Acts as a chaperone (By similarity)
HFP48_RS21400	ENOG4105CFG	Acts as a chaperone (By similarity)
HFP48_RS21430	ENOG4105DF6	Fe-S oxidoreductase
HFP48_RS21440	ENOG4105EEF	Alkane 1-monooxygenase
HFP48_RS21460	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
HFP48_RS21465	ENOG4105BZU	Histidine kinase
HFP48_RS21485	ENOG4105KJF	protein tyrosine phosphatase
HFP48_RS21490	ENOG4107YJ4	chain length determinant protein
HFP48_RS21510	ENOG4105D70	Integrase catalytic subunit
HFP48_RS21530	ENOG4105EXC	Acyl-transferase
HFP48_RS21575	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
HFP48_RS21580	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
HFP48_RS21585	ENOG4105EIP	mannose-6-phosphate isomerase
HFP48_RS21650	ENOG4105F27	Major Facilitator
HFP48_RS21655	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
HFP48_RS21670	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
HFP48_RS21720	ENOG4107QHE	Choloylglycine hydrolase
HFP48_RS21810	ENOG4105ECQ	AraC Family Transcriptional Regulator
HFP48_RS21830	ENOG4107258	Transcriptional regulator
HFP48_RS21835	ENOG4108RZE	Tetr family transcriptional regulator
HFP48_RS21850	ENOG4107R95	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
HFP48_RS21855	ENOG4105PDP	Short chain dehydrogenase
HFP48_RS21945	ENOG4108EQM	faD-dependent pyridine nucleotide-disulfide oxidoreductase
HFP48_RS21970	ENOG41068W2	Cytochrome p-450
HFP48_RS21995	ENOG4108ZXC	Two component transcriptional regulator, luxr family
HFP48_RS22030	ENOG4105BZP	glycoside hydrolase 15-related
HFP48_RS22045	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HFP48_RS22070	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
HFP48_RS22075	ENOG410905P	Pyridoxamine 5-phosphate
HFP48_RS22085	ENOG4105DHP	deoxycytidine triphosphate deaminase
HFP48_RS22110	ENOG4107ZR7	Membrane
HFP48_RS22135	ENOG4105CEY	Amp-dependent synthetase and ligase
HFP48_RS22145	ENOG4105C1G	acyl-Coa dehydrogenase
HFP48_RS22150	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
HFP48_RS22155	ENOG4105E2B	Taurine dioxygenase
HFP48_RS22175	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HFP48_RS22195	ENOG41080HT	Transcriptional regulator, arsr family
HFP48_RS22200	ENOG4107RDB	Major Facilitator
HFP48_RS22230	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
HFP48_RS22240	ENOG4105J5T	Amp-dependent synthetase and ligase
HFP48_RS22250	ENOG4105H3G	oxidoreductase
HFP48_RS22255	ENOG4108IG5	Transcriptional regulator
HFP48_RS22260	ENOG4108JGH	Tetr family transcriptional regulator
HFP48_RS22265	ENOG4105CEY	Amp-dependent synthetase and ligase
HFP48_RS22275	ENOG4105EUZ	Beta-lactamase domain protein
HFP48_RS22290	ENOG4108S4H	thioesterase Superfamily protein
HFP48_RS22310	ENOG4105DIA	mandelate racemase muconate lactonizing
HFP48_RS22320	ENOG4105DJB	Major Facilitator Superfamily
HFP48_RS22365	ENOG4105C1G	acyl-Coa dehydrogenase
HFP48_RS22370	ENOG4108R0M	Aminoglycoside
HFP48_RS22380	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
HFP48_RS22385	ENOG4105C32	Amino acid ABC transporter (Permease)
HFP48_RS22390	ENOG4108IV0	ABC, transporter
HFP48_RS22395	ENOG4105C0Z	ABC transporter
HFP48_RS22405	ENOG4105CEY	Amp-dependent synthetase and ligase
HFP48_RS22415	ENOG4105C7I	Dehydrogenase
HFP48_RS22420	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
HFP48_RS22450	ENOG4105C26	Dehydrogenase
HFP48_RS22460	ENOG4105D5Q	Arginine ornithine antiporter
HFP48_RS22475	ENOG4105DWY	Agmatine deiminase
HFP48_RS22480	ENOG4105C5F	glutamine synthetase
HFP48_RS22495	ENOG4105CHR	reductase
HFP48_RS22510	ENOG4105CHU	acetyl-coa acetyltransferase
HFP48_RS22520	ENOG4108KC2	acyl-Coa dehydrogenase
HFP48_RS22530	ENOG4105X7H	acyl-CoA dehydrogenase
HFP48_RS22535	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
HFP48_RS22540	ENOG4105CHR	reductase
HFP48_RS22545	ENOG4105J5T	Amp-dependent synthetase and ligase
HFP48_RS22550	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HFP48_RS22555	ENOG4105CEY	Amp-dependent synthetase and ligase
HFP48_RS22560	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
HFP48_RS22580	ENOG4105D2B	acyl-CoA dehydrogenase
HFP48_RS22585	ENOG4105F2C	Acetyl-CoA acetyltransferase
HFP48_RS22590	ENOG4108SGK	Tetr family transcriptional regulator
HFP48_RS22595	ENOG4108KC1	acyl-Coa dehydrogenase
HFP48_RS22700	ENOG4105H37	Glyoxalase Bleomycin resistance protein (Dioxygenase
HFP48_RS22710	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
HFP48_RS22715	ENOG4105DIV	Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (By similarity)
HFP48_RS22720	ENOG4105IKQ	hydratase
HFP48_RS22730	ENOG4105MXW	flavin reductase domain protein, FMN-binding
HFP48_RS22760	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HFP48_RS22765	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HFP48_RS22775	ENOG4108J59	Extracellular solute-binding protein, family 5
HFP48_RS22790	ENOG4107S8C	mandelate racemase muconate lactonizing
HFP48_RS22795	ENOG410880H	cysteine synthase
HFP48_RS22805	ENOG4105C12	Phosphoribosylglycinamide synthetase
HFP48_RS22825	ENOG4107W6X	Transcriptional regulator
HFP48_RS22835	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
HFP48_RS22840	ENOG4107QN2	dihydrolipoyl dehydrogenase
HFP48_RS22850	ENOG4105CPP	Dehydrogenase, E1 component
HFP48_RS22855	ENOG4107R0V	Pyruvate dehydrogenase
HFP48_RS22885	ENOG4105CHR	reductase
HFP48_RS22910	ENOG4105HMD	
HFP48_RS22930	ENOG4105CHR	reductase
HFP48_RS22940	ENOG41064MX	Tetr family transcriptional regulator
HFP48_RS22960	ENOG4105DDN	Pentapeptide repeat-containing protein
HFP48_RS23010	ENOG4105DU1	integral membrane protein, terc
HFP48_RS23025	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
HFP48_RS23045	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HFP48_RS23055	ENOG41088CC	tellurite resistance protein tehB
HFP48_RS23060	ENOG4105CSU	acyl-Coa dehydrogenase
HFP48_RS23070	ENOG4105CHU	acetyl-coa acetyltransferase
HFP48_RS23075	ENOG4105CHR	reductase
HFP48_RS23095	ENOG4105EEF	Alkane 1-monooxygenase
HFP48_RS23100	ENOG41084UD	rubredoxin
HFP48_RS23105	ENOG4105VCQ	rubredoxin
HFP48_RS23115	ENOG4107Z3H	Transcriptional regulator, TetR family
HFP48_RS23140	ENOG41073B4	coagulation factor 5 8 type domain-containing protein
HFP48_RS23165	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HFP48_RS23170	ENOG4108M6P	methyltransferase
HFP48_RS23200	ENOG4105D7W	serine acetyltransferase
HFP48_RS23225	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
HFP48_RS23245	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
HFP48_RS23265	ENOG4105MUA	Resistance protein
HFP48_RS23305	ENOG4108YYC	ycei family
HFP48_RS23315	ENOG4105DUX	Transporter
HFP48_RS23330	ENOG4105CJN	penicillin-binding protein
HFP48_RS23340	ENOG4106TYC	homoserine o-acetyltransferase (EC 2.3.1.31)
HFP48_RS23365	ENOG4105C1G	acyl-Coa dehydrogenase
HFP48_RS23430	ENOG410832A	alpha/beta hydrolase fold
HFP48_RS23450	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HFP48_RS23470	ENOG4105C1G	acyl-Coa dehydrogenase
HFP48_RS23475	ENOG4105CI0	Citrate lyase
HFP48_RS23480	ENOG4105DJG	MaoC domain protein dehydratase
HFP48_RS23485	ENOG4105K51	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
HFP48_RS23490	ENOG4105E39	Enoyl-CoA hydratase
HFP48_RS23495	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HFP48_RS23500	ENOG4105CD3	dihydroorotase
HFP48_RS23520	ENOG41081R7	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
HFP48_RS23540	ENOG4105D2B	acyl-CoA dehydrogenase
HFP48_RS23560	ENOG4108UKI	Enoyl-CoA hydratase
HFP48_RS23600	ENOG4108RAV	Conserved protein
HFP48_RS23605	ENOG4105DWF	phosphomethylpyrimidine kinase
HFP48_RS23610	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
HFP48_RS23630	ENOG4105EUB	pirin domain protein
HFP48_RS23660	ENOG4105C9K	Endothelin-converting enzyme 1
HFP48_RS23710	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
HFP48_RS23720	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
HFP48_RS23735	ENOG4105BZU	Histidine kinase
HFP48_RS23740	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
HFP48_RS23745	ENOG4105BZU	Histidine kinase
HFP48_RS23765	ENOG4108Q89	anthranilate 1,2-dioxygenase large subunit
HFP48_RS23775	ENOG4108R85	Short chain dehydrogenase
HFP48_RS23785	ENOG4108ZXC	Two component transcriptional regulator, luxr family
HFP48_RS23795	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HFP48_RS23815	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HFP48_RS23840	ENOG4108IJG	ABC transporter substrate-binding protein
HFP48_RS23855	ENOG4107UBC	ErfK ybiS ycfS ynhG family protein
HFP48_RS23865	ENOG4105WKW	Pfam:DUF1458
HFP48_RS23885	ENOG4105GN4	DNA ligase
HFP48_RS23895	ENOG4105D7N	magnesium and cobalt transport protein CorA
HFP48_RS23945	ENOG4105C59	p-type ATPase
HFP48_RS23955	ENOG4107R16	Multicopper oxidase
HFP48_RS23965	ENOG4108PYU	two-component system response regulator
HFP48_RS23970	ENOG4105BZU	Histidine kinase
HFP48_RS23985	ENOG4105CEY	Amp-dependent synthetase and ligase
HFP48_RS24015	ENOG4105CPC	Aldo Keto reductase
HFP48_RS24025	ENOG4105C01	Dihydroxy-acid dehydratase
HFP48_RS24030	ENOG41080HT	Transcriptional regulator, arsr family
HFP48_RS24035	ENOG4107TPS	domain protein
HFP48_RS24045	ENOG4107XUC	SirA family
HFP48_RS24050	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
HFP48_RS24055	ENOG4107QY8	reductase
HFP48_RS24075	ENOG4108QER	Adenylate cyclase
HFP48_RS24150	ENOG4105CEY	Amp-dependent synthetase and ligase
HFP48_RS24155	ENOG4108K8K	Transcriptional regulator
HFP48_RS24180	ENOG4105D3R	alkyl hydroperoxide reductase
HFP48_RS24225	ENOG4105D70	Integrase catalytic subunit
HFP48_RS24240	ENOG4106PVI	ATP-dependent carboxylate-amine ligase (By similarity)
HFP48_RS24250	ENOG4108IQK	o-acetylhomoserine
HFP48_RS24265	ENOG4105HS2	Arsenate reductase
HFP48_RS24270	ENOG41082BM	Transcriptional regulator, arsr family
HFP48_RS24285	ENOG4105HS2	Arsenate reductase
HFP48_RS24295	ENOG4105H3G	oxidoreductase
HFP48_RS24320	ENOG4105E8R	UPF0173 metal-dependent hydrolase
HFP48_RS24325	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
HFP48_RS24335	ENOG4105BZ8	glutamate synthase
HFP48_RS24355	ENOG4108IPW	abc transporter atp-binding protein
HFP48_RS24360	ENOG4105CM4	permease protein
HFP48_RS24365	ENOG4105DHS	permease protein
HFP48_RS24375	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
HFP48_RS24380	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HFP48_RS24400	ENOG4105CEY	Amp-dependent synthetase and ligase
HFP48_RS24405	ENOG4105E39	Enoyl-CoA hydratase
HFP48_RS24410	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
HFP48_RS24445	ENOG4105ECW	sulfate abc transporter
HFP48_RS24470	ENOG4105CC9	acyl-Coa dehydrogenase
HFP48_RS24480	ENOG4108M8W	Monooxygenase
HFP48_RS24485	ENOG410846T	CoA-transferase family III
HFP48_RS24490	ENOG4105CHR	reductase
HFP48_RS24500	ENOG4105DXB	Major Facilitator superfamily
HFP48_RS24515	ENOG4105DYW	oxidoreductase
HFP48_RS24525	ENOG4105C1G	acyl-Coa dehydrogenase
HFP48_RS24550	ENOG4105CHR	reductase
HFP48_RS24590	ENOG4108IG5	Transcriptional regulator
HFP48_RS24595	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HFP48_RS24610	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HFP48_RS24630	ENOG4107ZR7	Membrane
HFP48_RS24640	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
HFP48_RS24645	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
HFP48_RS24680	ENOG4105CEY	Amp-dependent synthetase and ligase
HFP48_RS24705	ENOG4107S1E	Beta-lactamase
HFP48_RS24745	ENOG4106HB6	Alpha beta hydrolase
HFP48_RS24765	ENOG4107RR1	TRANSCRIPTIONal
HFP48_RS24770	ENOG4105CHR	reductase
HFP48_RS24785	ENOG41067SE	Tetr family transcriptional regulator
HFP48_RS24820	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
HFP48_RS24825	ENOG4105EW9	transcriptional regulator AsnC family
HFP48_RS24830	ENOG4105D82	Glutamate dehydrogenase
HFP48_RS24835	ENOG4105C85	amino acid
HFP48_RS24840	ENOG4105CHR	reductase
HFP48_RS24845	ENOG4105CHR	reductase
HFP48_RS24850	ENOG4105CHU	acetyl-coa acetyltransferase
HFP48_RS24855	ENOG4105C1G	acyl-Coa dehydrogenase
HFP48_RS24920	ENOG4105K56	Transcriptional regulator
HFP48_RS24930	ENOG4105E2Q	3-(3-hydroxy-phenyl)propionate hydroxylase
HFP48_RS24935	ENOG4105KIU	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
HFP48_RS24940	ENOG41080R8	Conserved Protein
HFP48_RS24950	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
HFP48_RS24955	ENOG4105DAA	L-lactate
HFP48_RS24965	ENOG4105FDP	GntR family transcriptional regulator
HFP48_RS24975	ENOG4107WSY	Domain of unknown function DUF20
HFP48_RS25015	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
HFP48_RS25020	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
HFP48_RS25025	ENOG4107HP6	Transcriptional regulator
HFP48_RS25030	ENOG4105CHU	acetyl-coa acetyltransferase
HFP48_RS25040	ENOG4105KME	endoribonuclease L-psp
HFP48_RS25065	ENOG4105C7K	acetolactate synthase
HFP48_RS25135	ENOG4108KB2	LysR family Transcriptional regulator
HFP48_RS25140	ENOG4105E5G	Alpha beta hydrolase fold
HFP48_RS25145	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
HFP48_RS25165	ENOG4105DTQ	mandelate racemase muconate lactonizing
HFP48_RS25170	ENOG4108QMY	dioxygenase
HFP48_RS25175	ENOG4107HP6	Transcriptional regulator
HFP48_RS25185	ENOG4105MXW	flavin reductase domain protein, FMN-binding
HFP48_RS25215	ENOG4105FUY	alpha subunit
HFP48_RS25235	ENOG4105D2S	major facilitator superfamily
HFP48_RS25255	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
HFP48_RS25260	ENOG4107RN6	Monooxygenase
HFP48_RS25300	ENOG4105E2B	Taurine dioxygenase
HFP48_RS25315	ENOG4105CEY	Amp-dependent synthetase and ligase
HFP48_RS25325	ENOG41083WA	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HFP48_RS25335	ENOG4108VJY	integral membrane protein
HFP48_RS25345	ENOG4108UMN	azlc family
HFP48_RS25355	ENOG4107QP8	phosphohexose isomerase
HFP48_RS25360	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
HFP48_RS25365	ENOG4107S2E	monooxygenase
HFP48_RS25390	ENOG4108EQM	faD-dependent pyridine nucleotide-disulfide oxidoreductase
HFP48_RS25405	ENOG4108QBF	Transcriptional regulator
HFP48_RS25410	ENOG4105CGU	Enoyl-CoA hydratase
HFP48_RS25430	ENOG41076PI	Short-chain dehydrogenase reductase Sdr
HFP48_RS25435	ENOG4105H3G	oxidoreductase
HFP48_RS25450	ENOG4107S2E	monooxygenase
HFP48_RS25455	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HFP48_RS25465	ENOG41076PI	Short-chain dehydrogenase reductase Sdr
HFP48_RS25490	ENOG4105DQU	oxidoreductase, subunit beta
HFP48_RS25495	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
HFP48_RS25505	ENOG4105CHR	reductase
HFP48_RS25540	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
HFP48_RS25550	ENOG41076PI	Short-chain dehydrogenase reductase Sdr
HFP48_RS25565	ENOG4105CEY	Amp-dependent synthetase and ligase
HFP48_RS25570	ENOG4105C26	Dehydrogenase
HFP48_RS25585	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HFP48_RS25590	ENOG4105C26	Dehydrogenase
HFP48_RS25595	ENOG4105DJG	MaoC domain protein dehydratase
HFP48_RS25615	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
HFP48_RS25620	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
HFP48_RS25635	ENOG4105CHU	acetyl-coa acetyltransferase
HFP48_RS25655	ENOG4108IV0	ABC, transporter
HFP48_RS25660	ENOG4105C0Z	ABC transporter
HFP48_RS25685	ENOG4108Z4U	Ferredoxin
HFP48_RS25700	ENOG4107XCH	Cyclase family
HFP48_RS25740	ENOG4105J5T	Amp-dependent synthetase and ligase
HFP48_RS25755	ENOG4108RK3	acyl-Coa dehydrogenase
HFP48_RS25760	ENOG4105X7H	acyl-CoA dehydrogenase
HFP48_RS25765	ENOG4105D2B	acyl-CoA dehydrogenase
HFP48_RS25770	ENOG4105F2C	Acetyl-CoA acetyltransferase
HFP48_RS25775	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HFP48_RS25800	ENOG4108RZE	Tetr family transcriptional regulator
HFP48_RS25805	ENOG4105IYB	L-carnitine dehydratase bile acid-inducible protein F
HFP48_RS25810	ENOG4105CHU	acetyl-coa acetyltransferase
HFP48_RS25815	ENOG4105CEY	Amp-dependent synthetase and ligase
HFP48_RS25820	ENOG41082A2	Alpha beta hydrolase
HFP48_RS25830	ENOG4105C1G	acyl-Coa dehydrogenase
HFP48_RS25880	ENOG4105CPC	Aldo Keto reductase
HFP48_RS25885	ENOG4105ETE	Transcriptional regulator (LacI family
HFP48_RS25890	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
HFP48_RS25935	ENOG4105DAX	Pfam:DUF2983
HFP48_RS25970	ENOG4105CEY	Amp-dependent synthetase and ligase
HFP48_RS25980	ENOG4105CEY	Amp-dependent synthetase and ligase
HFP48_RS26005	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HFP48_RS26020	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HFP48_RS26035	ENOG4105CHR	reductase
HFP48_RS26070	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HFP48_RS26075	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HFP48_RS26090	ENOG4105CEY	Amp-dependent synthetase and ligase
HFP48_RS26105	ENOG4105CPC	Aldo Keto reductase
HFP48_RS26125	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
HFP48_RS26130	ENOG4105CHR	reductase
HFP48_RS26150	ENOG4105C1G	acyl-Coa dehydrogenase
HFP48_RS26160	ENOG4105E39	Enoyl-CoA hydratase
HFP48_RS26185	ENOG4105CHU	acetyl-coa acetyltransferase
HFP48_RS26190	ENOG4105CGU	Enoyl-CoA hydratase
HFP48_RS26200	ENOG4105CHR	reductase
HFP48_RS26225	ENOG4105DVW	rieske (2Fe-2S)
HFP48_RS26245	ENOG4105CC9	acyl-Coa dehydrogenase
HFP48_RS26250	ENOG4105D2B	acyl-CoA dehydrogenase
HFP48_RS26260	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HFP48_RS26270	ENOG4105CC9	acyl-Coa dehydrogenase
HFP48_RS26275	ENOG4105D2B	acyl-CoA dehydrogenase
HFP48_RS26300	ENOG4105CHU	acetyl-coa acetyltransferase
HFP48_RS26305	ENOG4105CEY	Amp-dependent synthetase and ligase
HFP48_RS26325	ENOG41076PI	Short-chain dehydrogenase reductase Sdr
HFP48_RS26335	ENOG4105CC9	acyl-Coa dehydrogenase
HFP48_RS26340	ENOG4105D2B	acyl-CoA dehydrogenase
HFP48_RS26365	ENOG4105C3U	ABC transporter
HFP48_RS26380	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
HFP48_RS26395	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
HFP48_RS26410	ENOG4105C5X	domain protein
HFP48_RS26435	ENOG4105C1G	acyl-Coa dehydrogenase
HFP48_RS26440	ENOG4105CEY	Amp-dependent synthetase and ligase
HFP48_RS26450	ENOG4105CHU	acetyl-coa acetyltransferase
HFP48_RS26455	ENOG4105DJB	Major Facilitator Superfamily
HFP48_RS26460	ENOG4105IYB	L-carnitine dehydratase bile acid-inducible protein F
HFP48_RS26465	ENOG4105C1G	acyl-Coa dehydrogenase
HFP48_RS26485	ENOG4107TYG	Oxidoreductase domain-containing protein
HFP48_RS26490	ENOG4105CV8	reductase
HFP48_RS26500	ENOG4107S9B	Shikimate dehydrogenase
HFP48_RS26505	ENOG4105CSH	Transporter
HFP48_RS26510	ENOG4107RSM	transcriptional regulator
HFP48_RS26515	ENOG4106517	Short-chain dehydrogenase reductase Sdr
HFP48_RS26525	ENOG4107258	Transcriptional regulator
HFP48_RS26550	ENOG4108UQY	Iron-storage protein
HFP48_RS26555	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
HFP48_RS26570	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HFP48_RS26610	ENOG4108MMM	RNA Polymerase
HFP48_RS26615	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HFP48_RS26630	ENOG4105E2R	ROK family
HFP48_RS26635	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
HFP48_RS26640	ENOG4105C01	Dihydroxy-acid dehydratase
HFP48_RS26645	ENOG4108UHU	Aldolase
HFP48_RS26660	ENOG4107Z6I	Thiamine biosynthesis protein
HFP48_RS26665	ENOG4105D7T	ABC transporter
HFP48_RS26670	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
HFP48_RS26675	ENOG4105C6F	GntR Family Transcriptional Regulator
HFP48_RS26680	ENOG4105E2R	ROK family
HFP48_RS26690	ENOG4105DKQ	ROK family
HFP48_RS26755	ENOG4105CXN	decarboxylase
HFP48_RS26780	ENOG4105C7W	Xanthine dehydrogenase
HFP48_RS26790	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
HFP48_RS26835	ENOG4105BZP	glycoside hydrolase 15-related
HFP48_RS26865	ENOG4108UZX	fmn reductase
HFP48_RS26910	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
HFP48_RS26930	ENOG4105CSH	Transporter
HFP48_RS26935	ENOG4105CEY	Amp-dependent synthetase and ligase
HFP48_RS26940	ENOG4105IDI	abc transporter atp-binding protein
HFP48_RS26960	ENOG4105CBC	glutamate synthase
HFP48_RS26975	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
HFP48_RS26995	ENOG4105D3R	alkyl hydroperoxide reductase
HFP48_RS27005	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HFP48_RS27015	ENOG4108DBC	nitroreductase
HFP48_RS27020	ENOG4108M8W	Monooxygenase
HFP48_RS27030	ENOG4105D01	(LipO)protein
HFP48_RS27035	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HFP48_RS27040	ENOG4108UMI	ABC transporter, permease
HFP48_RS27045	ENOG4107ZR7	Membrane
HFP48_RS27050	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HFP48_RS27070	ENOG4105NAE	bifunctional deaminase-reductase domain protein
HFP48_RS27080	ENOG4105D2S	major facilitator superfamily
HFP48_RS27090	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
HFP48_RS27095	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
HFP48_RS27100	ENOG4107YH6	single-stranded DNA-binding protein
HFP48_RS27105	ENOG410829C	Binds together with S18 to 16S ribosomal RNA (By similarity)
HFP48_RS27135	ENOG4105BZ4	penicillin-binding protein
HFP48_RS27160	ENOG4105VUN	Transcriptional regulator
HFP48_RS27180	ENOG4105C1G	acyl-Coa dehydrogenase
HFP48_RS27200	ENOG4105BZ4	penicillin-binding protein
HFP48_RS27275	ENOG4105W2E	Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth (By similarity)
HFP48_RS27295	ENOG4105C1G	acyl-Coa dehydrogenase
HFP48_RS27300	ENOG4105CC9	acyl-Coa dehydrogenase
HFP48_RS27335	ENOG4105E5Q	amino acid AbC transporter
HFP48_RS27340	ENOG4105CDA	abc transporter atp-binding protein
HFP48_RS27375	ENOG4105CHU	acetyl-coa acetyltransferase
HFP48_RS27390	ENOG4105C1G	acyl-Coa dehydrogenase
HFP48_RS27395	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HFP48_RS27405	ENOG4105DUM	transcriptional regulator, lysR family
HFP48_RS27420	ENOG4105CHR	reductase
HFP48_RS27425	ENOG4105CSU	acyl-Coa dehydrogenase
HFP48_RS27430	ENOG4105CHR	reductase
HFP48_RS27445	ENOG4105DRR	Transcriptional regulator, GntR family
HFP48_RS27450	ENOG4105E2B	Taurine dioxygenase
HFP48_RS27455	ENOG4105EFP	binding-protein-dependent transport systems inner membrane Component
HFP48_RS27470	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HFP48_RS27475	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HFP48_RS27480	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HFP48_RS27490	ENOG4107ZR7	Membrane
HFP48_RS27510	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
HFP48_RS27520	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
HFP48_RS27525	ENOG4105DJB	Major Facilitator Superfamily
HFP48_RS27545	ENOG4107VHA	regulatoR
HFP48_RS27560	ENOG4105CEY	Amp-dependent synthetase and ligase
HFP48_RS27565	ENOG4105C85	amino acid
HFP48_RS27595	ENOG4105VG9	Plasmid stabilization system
HFP48_RS27600	ENOG41067D0	Antitoxin component of a toxin-antitoxin (TA) module. Upon expression in M.smegmatis neutralizes the effect of toxin RelE2
HFP48_RS27615	ENOG4105C26	Dehydrogenase
HFP48_RS27620	ENOG4105C1G	acyl-Coa dehydrogenase
HFP48_RS27625	ENOG4108JPW	Aminotransferase
HFP48_RS27630	ENOG4105C7I	Dehydrogenase
HFP48_RS27640	ENOG41070H7	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
HFP48_RS27645	ENOG4105DQ4	alcohol dehydrogenase
HFP48_RS27665	ENOG4105CKQ	methane phenol toluene hydroxylase
HFP48_RS27670	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
HFP48_RS27675	ENOG4105EUX	methane phenol toluene hydroxylase
HFP48_RS27685	ENOG4105CH6	catalase
HFP48_RS27700	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HFP48_RS27735	ENOG4105E2Q	3-(3-hydroxy-phenyl)propionate hydroxylase
HFP48_RS27745	ENOG4105CEY	Amp-dependent synthetase and ligase
HFP48_RS27785	ENOG4105DCG	PHP domain protein
HFP48_RS27815	ENOG4105C37	(CBS) domain
HFP48_RS27825	ENOG4105E5G	Alpha beta hydrolase fold
HFP48_RS27830	ENOG4105C8T	Leucyl-tRNA synthetase
HFP48_RS27855	ENOG4105CVK	Glutamate decarboxylase
HFP48_RS27860	ENOG41081DT	UPF0301 protein
HFP48_RS27910	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
HFP48_RS27915	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
HFP48_RS27955	ENOG4108JGH	Tetr family transcriptional regulator
HFP48_RS27960	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HFP48_RS27975	ENOG4105C3M	thioredoxin reductase
HFP48_RS27980	ENOG4105C3M	thioredoxin reductase
HFP48_RS27985	ENOG4108E1C	hydrolase
HFP48_RS28000	ENOG4107QJE	Chromosome Partitioning Protein
HFP48_RS28005	ENOG4107XUG	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
HFP48_RS28015	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HFP48_RS28020	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
HFP48_RS28025	ENOG4105XH8	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
HFP48_RS28030	ENOG41084CH	50S ribosomal protein l34
HFP48_RS28110	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
HFP48_RS28115	ENOG4105CHU	acetyl-coa acetyltransferase
HFP48_RS28140	ENOG4105D2B	acyl-CoA dehydrogenase
HFP48_RS28145	ENOG4105D2B	acyl-CoA dehydrogenase
HFP48_RS28150	ENOG4105CHR	reductase
HFP48_RS28155	ENOG4105CHR	reductase
HFP48_RS28160	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
HFP48_RS28165	ENOG4105MXW	flavin reductase domain protein, FMN-binding
HFP48_RS28205	ENOG4105CSH	Transporter
HFP48_RS28230	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
HFP48_RS28235	ENOG4105VG5	Membrane
HFP48_RS28240	ENOG4105CSH	Transporter
HFP48_RS28245	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
HFP48_RS28305	ENOG4105D2B	acyl-CoA dehydrogenase
HFP48_RS28310	ENOG4105CEY	Amp-dependent synthetase and ligase
HFP48_RS28335	ENOG4105CC9	acyl-Coa dehydrogenase
HFP48_RS28355	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HFP48_RS28360	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HFP48_RS28365	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
HFP48_RS28370	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
HFP48_RS28385	ENOG4106YKD	Cytochrome p-450
HFP48_RS28395	ENOG41076PI	Short-chain dehydrogenase reductase Sdr
HFP48_RS28400	ENOG4105C6F	GntR Family Transcriptional Regulator
HFP48_RS28415	ENOG4105CEV	competence damage-inducible protein
HFP48_RS28480	ENOG4105C57	major facilitator superfamily
HFP48_RS28510	ENOG4108IG5	Transcriptional regulator
HFP48_RS28555	ENOG4105D2B	acyl-CoA dehydrogenase
HFP48_RS28560	ENOG4105D2B	acyl-CoA dehydrogenase
HFP48_RS28565	ENOG4105F2C	Acetyl-CoA acetyltransferase
HFP48_RS28570	ENOG4105CHR	reductase
HFP48_RS28575	ENOG4105D2S	major facilitator superfamily
HFP48_RS28615	ENOG4108M9J	MaoC like domain protein
HFP48_RS28715	ENOG4108R6W	Transcriptional regulator, ARAC family
HFP48_RS28740	ENOG4105EKQ	RNA-directed DNA polymerase
HFP48_RS28750	ENOG4105CHR	reductase
HFP48_RS28795	ENOG4105BZW	Glycerate kinase
HFP48_RS28840	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
HFP48_RS28845	ENOG4105CMD	Transcriptional regulator, GntR family
HFP48_RS28850	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
HFP48_RS28885	ENOG4105CEY	Amp-dependent synthetase and ligase
HFP48_RS28890	ENOG4105CSU	acyl-Coa dehydrogenase
HFP48_RS28895	ENOG4105CHR	reductase
HFP48_RS28900	ENOG4105CHR	reductase
HFP48_RS28905	ENOG4105CHU	acetyl-coa acetyltransferase
HFP48_RS28920	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HFP48_RS28925	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HFP48_RS28935	ENOG41067SE	Tetr family transcriptional regulator
HFP48_RS28965	ENOG4107S2E	monooxygenase
HFP48_RS28985	ENOG4105CEY	Amp-dependent synthetase and ligase
HFP48_RS28990	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
HFP48_RS28995	ENOG4105F95	Monooxygenase
HFP48_RS29040	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HFP48_RS29045	ENOG4105E2A	Dehydrogenase
HFP48_RS29055	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
HFP48_RS29065	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
HFP48_RS29095	ENOG4108TKH	Nitroreductase
HFP48_RS29115	ENOG4105F95	Monooxygenase
HFP48_RS29120	ENOG4105CEY	Amp-dependent synthetase and ligase
HFP48_RS29160	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HFP48_RS29190	ENOG4105CSH	Transporter
HFP48_RS29195	ENOG4106YT9	Enoyl-CoA hydratase
HFP48_RS29200	ENOG41067SE	Tetr family transcriptional regulator
HFP48_RS29205	ENOG4105CHU	acetyl-coa acetyltransferase
HFP48_RS29210	ENOG4105CHR	reductase
HFP48_RS29235	ENOG4105DWV	Homoserine O-trans-acetylase
HFP48_RS29240	ENOG4105F95	Monooxygenase
HFP48_RS29260	ENOG4105F9F	transposase
HFP48_RS29315	ENOG4108JQ7	(ABC) transporter
HFP48_RS29335	ENOG4107TE1	transport protein
HFP48_RS29340	ENOG4105CEY	Amp-dependent synthetase and ligase
HFP48_RS29375	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
HFP48_RS29380	ENOG4105CHR	reductase
HFP48_RS29430	ENOG4105CGU	Enoyl-CoA hydratase
HFP48_RS29440	ENOG4105C1G	acyl-Coa dehydrogenase
HFP48_RS29445	ENOG4105CHR	reductase
HFP48_RS29495	ENOG4105CEY	Amp-dependent synthetase and ligase
HFP48_RS29525	ENOG4105CHR	reductase
HFP48_RS29530	ENOG4105E39	Enoyl-CoA hydratase
HFP48_RS29535	ENOG4105Q56	cytochrome P450
HFP48_RS29540	ENOG4105E39	Enoyl-CoA hydratase
HFP48_RS29545	ENOG4105EA8	2-Nitropropane dioxygenase
HFP48_RS29555	ENOG4108UKI	Enoyl-CoA hydratase
HFP48_RS29560	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
HFP48_RS29570	ENOG4105CHU	acetyl-coa acetyltransferase
HFP48_RS29575	ENOG4108KEZ	Dehydrogenase
HFP48_RS29580	ENOG4105CEY	Amp-dependent synthetase and ligase
HFP48_RS29590	ENOG4105CC9	acyl-Coa dehydrogenase
HFP48_RS29600	ENOG4105E39	Enoyl-CoA hydratase
HFP48_RS29605	ENOG4105CC9	acyl-Coa dehydrogenase
HFP48_RS29610	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HFP48_RS29620	ENOG4105CEY	Amp-dependent synthetase and ligase
HFP48_RS29625	ENOG4108R86	Transcriptional regulator
HFP48_RS29640	ENOG4105D2B	acyl-CoA dehydrogenase
HFP48_RS29650	ENOG4105C1G	acyl-Coa dehydrogenase
HFP48_RS29655	ENOG4105C29	acyl-CoA thioesterase
HFP48_RS29670	ENOG4105D2B	acyl-CoA dehydrogenase
HFP48_RS29675	ENOG4105CHU	acetyl-coa acetyltransferase
HFP48_RS29690	ENOG4105CHU	acetyl-coa acetyltransferase
HFP48_RS29695	ENOG4105EUJ	GTP cyclohydrolase i
HFP48_RS29740	ENOG4106F59	XRE family Transcriptional regulator
HFP48_RS29780	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
HFP48_RS29845	ENOG4105DND	Transcriptional regulator
HFP48_RS29850	ENOG4105CGU	Enoyl-CoA hydratase
HFP48_RS29855	ENOG4105C1G	acyl-Coa dehydrogenase
HFP48_RS29865	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HFP48_RS29870	ENOG4105CKK	Glycosyl transferase, family 2
HFP48_RS29920	ENOG4108JNI	Alpha beta hydrolase
HFP48_RS29965	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
HFP48_RS30025	ENOG4105CHR	reductase
HFP48_RS30030	ENOG4108M8W	Monooxygenase
HFP48_RS30055	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
HFP48_RS30070	ENOG4105JSC	dimethylmenaquinone methyltransferase
HFP48_RS30075	ENOG4105ERH	Fumarylacetoacetate hydrolase
HFP48_RS30085	ENOG4108IPT	Naphthoate synthase
HFP48_RS30130	ENOG4105CP9	extracellular ligand-binding receptor
HFP48_RS30140	ENOG4105C2J	ABC transporter
HFP48_RS30200	ENOG4105F2C	Acetyl-CoA acetyltransferase
HFP48_RS30215	ENOG4105D5G	Transposase
HFP48_RS30225	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HFP48_RS30230	ENOG4105C1G	acyl-Coa dehydrogenase
HFP48_RS30245	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HFP48_RS30260	ENOG4105CSH	Transporter
HFP48_RS30265	ENOG41076PI	Short-chain dehydrogenase reductase Sdr
HFP48_RS30280	ENOG4105CC9	acyl-Coa dehydrogenase
HFP48_RS30285	ENOG4105C1G	acyl-Coa dehydrogenase
HFP48_RS30290	ENOG4105CGU	Enoyl-CoA hydratase
HFP48_RS30325	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HFP48_RS30330	ENOG4105C1G	acyl-Coa dehydrogenase
HFP48_RS30340	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
HFP48_RS30355	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HFP48_RS30495	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
HFP48_RS30575	ENOG4108EU4	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HFP48_RS30815	ENOG410836F	Transposase
HFP48_RS30825	ENOG4107RY6	amino acid
HFP48_RS30835	ENOG4105H08	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HFP48_RS30875	ENOG410900G	Protein of unknown function (DUF421)
HFP48_RS30905	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
HFP48_RS30955	ENOG4107YAU	phenylacetic acid degradation protein
HFP48_RS30975	ENOG4108W2Y	isochorismatase
HFP48_RS30990	ENOG4105E9F	Enoyl-CoA hydratase
HFP48_RS30995	ENOG4105E39	Enoyl-CoA hydratase
HFP48_RS31010	ENOG4105VEQ	Cold shock protein
HFP48_RS31065	ENOG4105EYF	MMPL domain protein
HFP48_RS31080	ENOG410904A	RNA polymerase
HFP48_RS31130	ENOG410839S	Toxic component of a toxin-antitoxin (TA) module (By similarity)
HFP48_RS31135	ENOG4105E9K	Isocitrate dehydrogenase
HFP48_RS31195	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HFP48_RS31210	ENOG4105DB4