locus-tag	class	description
EXZ61_RS00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
EXZ61_RS00015	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
EXZ61_RS00020	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
EXZ61_RS00030	ENOG4105J0Q	Transcriptional regulator
EXZ61_RS00035	ENOG4107RN3	metallophosphoesterase
EXZ61_RS00040	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
EXZ61_RS00045	ENOG4107QMS	site-determining protein
EXZ61_RS00050	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
EXZ61_RS00095	ENOG4105DH7	May be involved in recombination (By similarity)
EXZ61_RS00140	ENOG4105C59	p-type ATPase
EXZ61_RS00145	ENOG4105CUT	histidyl-tRNA synthetase
EXZ61_RS00150	ENOG4105C8Q	Methyl-accepting chemotaxis
EXZ61_RS00160	ENOG4105C8Q	Methyl-accepting chemotaxis
EXZ61_RS00165	ENOG4108K3A	Glutathione S-transferase
EXZ61_RS00175	ENOG4107RGH	Aldehyde dehydrogenase
EXZ61_RS00180	ENOG4108W63	CRP FNR family transcriptional regulator
EXZ61_RS00190	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
EXZ61_RS00195	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
EXZ61_RS00205	ENOG4107QJE	Chromosome Partitioning Protein
EXZ61_RS00215	ENOG4105FA0	parb-like partition protein
EXZ61_RS00225	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
EXZ61_RS00235	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
EXZ61_RS00240	ENOG4105CP9	extracellular ligand-binding receptor
EXZ61_RS00245	ENOG4105CTU	Proline racemase
EXZ61_RS00250	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
EXZ61_RS00265	ENOG4108WYP	Transcriptional regulator
EXZ61_RS00285	ENOG4105BZU	Histidine kinase
EXZ61_RS00290	ENOG4105CPI	Metal Dependent Phosphohydrolase
EXZ61_RS00315	ENOG4105CS6	Rhs element vgr protein
EXZ61_RS00340	ENOG4105CQB	FAD linked oxidase domain protein
EXZ61_RS00350	ENOG4108WBT	adenosyltransferase
EXZ61_RS00360	ENOG4105KA0	thioesterase Superfamily protein
EXZ61_RS00365	ENOG4108IY8	ABC, transporter
EXZ61_RS00370	ENOG4108I05	Binding-protein-dependent transport systems, inner membrane component
EXZ61_RS00375	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
EXZ61_RS00380	ENOG4107XKF	NMT1 THI5 Like Domain Protein
EXZ61_RS00400	ENOG4105BZU	Histidine kinase
EXZ61_RS00455	ENOG4108IJ6	ABC transporter
EXZ61_RS00460	ENOG4105ECW	sulfate abc transporter
EXZ61_RS00465	ENOG4108I5D	sulfate abc transporter
EXZ61_RS00470	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
EXZ61_RS00480	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
EXZ61_RS00485	ENOG4105C9K	Endothelin-converting enzyme 1
EXZ61_RS00490	ENOG4105FDR	Membrane
EXZ61_RS00525	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
EXZ61_RS00535	ENOG4105WJV	Binding-protein-dependent transport systems, inner membrane component
EXZ61_RS00540	ENOG4108IJ8	ABC transporter
EXZ61_RS00545	ENOG4107T5X	Binding-protein-dependent transport systems, inner membrane component
EXZ61_RS00550	ENOG4107SI7	Substrate-binding region of abc-type glycine betaine transport system
EXZ61_RS00575	ENOG4105C0D	helicase
EXZ61_RS00580	ENOG4107QMH	DNA methylase
EXZ61_RS00585	ENOG4105DFS	Conserved Protein
EXZ61_RS00595	ENOG4105K63	Thioredoxin
EXZ61_RS00605	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
EXZ61_RS00615	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
EXZ61_RS00630	ENOG4105BZU	Histidine kinase
EXZ61_RS00645	ENOG4105EE5	Membrane protein terC
EXZ61_RS00660	ENOG4105JQN	Transcriptional regulator
EXZ61_RS00665	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
EXZ61_RS00685	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
EXZ61_RS00700	ENOG4105UIB	(ABC) transporter
EXZ61_RS00705	ENOG4108JQ9	ABC transporter
EXZ61_RS00710	ENOG4107TFB	basic membrane
EXZ61_RS00715	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
EXZ61_RS00720	ENOG4105CD3	dihydroorotase
EXZ61_RS00725	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
EXZ61_RS00730	ENOG4105BZ8	glutamate synthase
EXZ61_RS00765	ENOG4105C5H	ABC transporter
EXZ61_RS00770	ENOG4108Z12	YiaAB two helix domain-containing protein
EXZ61_RS00805	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EXZ61_RS00830	ENOG4105DND	Transcriptional regulator
EXZ61_RS00845	ENOG4105CJP	fad dependent oxidoreductase
EXZ61_RS00865	ENOG4108WYP	Transcriptional regulator
EXZ61_RS00870	ENOG4105C4Y	ABC transporter
EXZ61_RS00880	ENOG4107RCV	ABC transporter, permease
EXZ61_RS00885	ENOG4107THD	Involved in phosphonate degradation (By similarity)
EXZ61_RS00890	ENOG4106PMH	Extracellular solute-binding protein family 3
EXZ61_RS00895	ENOG4108K3Z	AraC family transcriptional regulator
EXZ61_RS00900	ENOG4105C5F	glutamine synthetase
EXZ61_RS00910	ENOG4105C0A	alcohol dehydrogenase
EXZ61_RS00930	ENOG4105FDP	GntR family transcriptional regulator
EXZ61_RS00935	ENOG4105CE4	GlcNAc 6-P deacetylase
EXZ61_RS00940	ENOG4105EB3	Histidine kinase
EXZ61_RS00945	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
EXZ61_RS00960	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
EXZ61_RS00970	ENOG4108IJ9	(ABC) transporter
EXZ61_RS00975	ENOG4105RD7	BadF BadG BcrA BcrD
EXZ61_RS01000	ENOG4105C9U	ATP-dependent DNA helicase RecQ
EXZ61_RS01010	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
EXZ61_RS01020	ENOG4105DHQ	Histidine kinase
EXZ61_RS01035	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
EXZ61_RS01040	ENOG4108004	Modulates RecA activity (By similarity)
EXZ61_RS01045	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
EXZ61_RS01050	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
EXZ61_RS01055	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
EXZ61_RS01060	ENOG4108ZCF	integral membrane protein
EXZ61_RS01065	ENOG4105D9P	serine threonine protein kinase
EXZ61_RS01070	ENOG4108ZF3	Phosphatase
EXZ61_RS01080	ENOG4105F8J	Adenylate Guanylate cyclase
EXZ61_RS01085	ENOG4107YM4	Beta-lactamase domain-containing protein
EXZ61_RS01090	ENOG4107QHF	type ii secretion system protein e
EXZ61_RS01100	ENOG4105ERG	peptidase m48, ste24p
EXZ61_RS01105	ENOG41086DT	Membrane protein of unknown function
EXZ61_RS01110	ENOG4108ZCF	integral membrane protein
EXZ61_RS01120	ENOG4108VWS	Yaeq family
EXZ61_RS01125	ENOG4107QTF	adenylosuccinate lyase
EXZ61_RS01130	ENOG4108U78	Glutathione S-transferase
EXZ61_RS01135	ENOG4105C8Q	Methyl-accepting chemotaxis
EXZ61_RS01140	ENOG4105K63	Thioredoxin
EXZ61_RS01145	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
EXZ61_RS01150	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
EXZ61_RS01155	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
EXZ61_RS01160	ENOG4105W3H	MtN3 and saliva related transmembrane protein
EXZ61_RS01165	ENOG4105BZU	Histidine kinase
EXZ61_RS01210	ENOG4107RVU	D-Ala-D-Ala carboxypeptidase 3 (S13) family
EXZ61_RS01220	ENOG41072GX	Peptidase M22 Glycoprotease
EXZ61_RS01235	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
EXZ61_RS01250	ENOG4105CYM	Glutathione S-transferase
EXZ61_RS01260	ENOG4105C8Q	Methyl-accepting chemotaxis
EXZ61_RS01270	ENOG4105QYK	bacteriophage lambda Bor protein homolog
EXZ61_RS01275	ENOG4105CQB	FAD linked oxidase domain protein
EXZ61_RS01300	ENOG4105DFS	Conserved Protein
EXZ61_RS01325	ENOG4105EUP	HipA domain protein
EXZ61_RS01355	ENOG4105EYH	Exonuclease
EXZ61_RS01360	ENOG4107RH8	nuclease SbcCD subunit D
EXZ61_RS01365	ENOG4106IUH	DTW domain containing protein
EXZ61_RS01385	ENOG4105EUB	pirin domain protein
EXZ61_RS01395	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
EXZ61_RS01405	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
EXZ61_RS01425	ENOG4105D6E	homoserine dehydrogenase
EXZ61_RS01430	ENOG4105CIH	Imidazole acetol-phosphate transaminase
EXZ61_RS01435	ENOG4108NIW	Leucine export protein LeuE
EXZ61_RS01490	ENOG4108RG0	uracil-dna glycosylase
EXZ61_RS01495	ENOG4105HEI	LysR family (Transcriptional regulator
EXZ61_RS01525	ENOG4105CF1	Alkylated DNA repair protein
EXZ61_RS01530	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
EXZ61_RS01560	ENOG4105W1N	transcriptional regulator
EXZ61_RS01565	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
EXZ61_RS01570	ENOG4105DDY	UPF0142 protein ycaO
EXZ61_RS01600	ENOG4105MGK	May be involved in the folding of the extracellular lipase during its passage through the periplasm (By similarity)
EXZ61_RS01605	ENOG4107IFA	Lipase (EC 3.1.1.3)
EXZ61_RS01635	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
EXZ61_RS01640	ENOG4105CV1	Transketolase (EC 2.2.1.1)
EXZ61_RS01645	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
EXZ61_RS01660	ENOG4105CFP	Peptidase U32
EXZ61_RS01715	ENOG4105EB3	Histidine kinase
EXZ61_RS01720	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
EXZ61_RS01730	ENOG4108S0S	Nucleotidyl transferase
EXZ61_RS01735	ENOG4107RAQ	aminopeptidase
EXZ61_RS01745	ENOG4105CEP	NADH dehydrogenase
EXZ61_RS01770	ENOG4105DJ4	phosphatidylserine decarboxylase
EXZ61_RS01775	ENOG4108W2P	Methyl-accepting chemotaxis
EXZ61_RS01800	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
EXZ61_RS01855	ENOG4105C8Q	Methyl-accepting chemotaxis
EXZ61_RS01875	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
EXZ61_RS01895	ENOG4105CB5	ATP-dependent DNA helicase recG
EXZ61_RS01910	ENOG4105DFI	Membrane
EXZ61_RS01920	ENOG4105RAK	Histidine kinase
EXZ61_RS01925	ENOG4105C5Q	Transcriptional regulator
EXZ61_RS01935	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
EXZ61_RS01945	ENOG4105C75	arginyL-tRNA synthetase
EXZ61_RS01965	ENOG4108IUZ	ABC transporter
EXZ61_RS01970	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
EXZ61_RS01975	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
EXZ61_RS01990	ENOG4105CBC	glutamate synthase
EXZ61_RS01995	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
EXZ61_RS02010	ENOG4105BZU	Histidine kinase
EXZ61_RS02020	ENOG4108ZAI	phosphatidylglycerophosphatase a
EXZ61_RS02025	ENOG4105C8V	SAICAR synthetase
EXZ61_RS02035	ENOG4105CA9	Pyruvate kinase
EXZ61_RS02040	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
EXZ61_RS02045	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
EXZ61_RS02050	ENOG4105BZU	Histidine kinase
EXZ61_RS02060	ENOG4105C8Q	Methyl-accepting chemotaxis
EXZ61_RS02065	ENOG4108V3W	Chemotaxis protein, CheW
EXZ61_RS02070	ENOG4105C8Q	Methyl-accepting chemotaxis
EXZ61_RS02075	ENOG4105CBS	Chea signal transduction histidine kinase
EXZ61_RS02085	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
EXZ61_RS02095	ENOG4105BZA	Phosphoglycerate kinase
EXZ61_RS02110	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
EXZ61_RS02115	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
EXZ61_RS02125	ENOG4105C79	DNA protecting protein DprA
EXZ61_RS02130	ENOG4108RPN	Protein smg homolog
EXZ61_RS02140	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
EXZ61_RS02145	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
EXZ61_RS02150	ENOG4105VIE	preprotein translocase, subunit YajC
EXZ61_RS02160	ENOG4105EW9	transcriptional regulator AsnC family
EXZ61_RS02175	ENOG4105CA3	membrane-bound lytic murein transglycosylase
EXZ61_RS02190	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
EXZ61_RS02195	ENOG4107Z67	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
EXZ61_RS02205	ENOG4108K3A	Glutathione S-transferase
EXZ61_RS02250	ENOG4107RDB	Major Facilitator
EXZ61_RS02255	ENOG4108UUM	single-stranded DNA-binding protein
EXZ61_RS02270	ENOG4107QJZ	Glycosyl transferase, family 2
EXZ61_RS02300	ENOG4108XTA	Together with AlgI and AlgF, forms an inner membrane complex which probably interacts with the alginate polymerization- transport complex and adds acetyl groups at the O-2 and O-3 positions of polymannuronic acid. Acetylation of alginate
EXZ61_RS02305	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
EXZ61_RS02315	ENOG4105EJG	cellulose synthase
EXZ61_RS02320	ENOG4107EEX	Cellulose synthase regulator protein
EXZ61_RS02340	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
EXZ61_RS02345	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
EXZ61_RS02350	ENOG4105W8H	transhydrogenase (subunit alpha
EXZ61_RS02355	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
EXZ61_RS02360	ENOG4105CEY	Amp-dependent synthetase and ligase
EXZ61_RS02365	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
EXZ61_RS02370	ENOG4107QUT	magnesium and cobalt transport protein CorA
EXZ61_RS02375	ENOG4105FCW	Major Facilitator superfamily
EXZ61_RS02445	ENOG4105UPP	uncharacterized protein ydcA
EXZ61_RS02475	ENOG4108WTW	DNA transposition protein
EXZ61_RS02490	ENOG4105IKI	host-nuclease inhibitor protein
EXZ61_RS02555	ENOG4105TKZ	Tail Sheath
EXZ61_RS02590	ENOG4105WR6	Phage protein, GP46
EXZ61_RS02640	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
EXZ61_RS02645	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
EXZ61_RS02650	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
EXZ61_RS02655	ENOG41090R7	Ferric uptake
EXZ61_RS02660	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
EXZ61_RS02675	ENOG4105SG9	biopolymer transport protein, ExbD
EXZ61_RS02680	ENOG4105C8T	Leucyl-tRNA synthetase
EXZ61_RS02690	ENOG4106KNT	transcriptional regulator
EXZ61_RS02710	ENOG4105DSP	amino acid AbC transporter
EXZ61_RS02715	ENOG4106YG3	ABC transporter
EXZ61_RS02725	ENOG4105E89	ABC transporter
EXZ61_RS02730	ENOG4108JEH	abc transporter atp-binding protein
EXZ61_RS02745	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
EXZ61_RS02760	ENOG4108JJA	ABC, transporter
EXZ61_RS02790	ENOG4105EMU	Dehydrogenase
EXZ61_RS02805	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
EXZ61_RS02815	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
EXZ61_RS02840	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
EXZ61_RS02845	ENOG4105BZU	Histidine kinase
EXZ61_RS02855	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
EXZ61_RS02860	ENOG4105C08	Histidine kinase
EXZ61_RS02865	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
EXZ61_RS02870	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
EXZ61_RS02875	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
EXZ61_RS02885	ENOG4105DFH	Transport of potassium into the cell (By similarity)
EXZ61_RS02890	ENOG4105DKK	Benzoate
EXZ61_RS02895	ENOG4105D7Z	glutathione synthase
EXZ61_RS02900	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
EXZ61_RS02910	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
EXZ61_RS02920	ENOG4105E7A	Glutamine amidotransferase
EXZ61_RS02925	ENOG41084KP	4-oxalocrotonate tautomerase
EXZ61_RS02955	ENOG4108ZHJ	Organic hydroperoxide resistance protein
EXZ61_RS02960	ENOG4105K56	Transcriptional regulator
EXZ61_RS02965	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
EXZ61_RS02990	ENOG4105DHT	Metal Dependent Phosphohydrolase
EXZ61_RS03005	ENOG4105CJ1	ABC, transporter
EXZ61_RS03010	ENOG4105FYV	Amp nucleosidase
EXZ61_RS03020	ENOG4108IGT	Dipeptidase
EXZ61_RS03055	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
EXZ61_RS03065	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
EXZ61_RS03105	ENOG4108594	Permease of the drug metabolite transporter
EXZ61_RS03120	ENOG4105H3G	oxidoreductase
EXZ61_RS03125	ENOG4107FW0	short-chain dehydrogenase reductase
EXZ61_RS03130	ENOG4108FUF	Transcriptional regulator, IclR family
EXZ61_RS03140	ENOG4108TEB	UPF0114 protein
EXZ61_RS03170	ENOG4107QP3	malate synthase g
EXZ61_RS03180	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
EXZ61_RS03195	ENOG4105II7	pyrroline-5-carboxylate reductase
EXZ61_RS03200	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
EXZ61_RS03205	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
EXZ61_RS03210	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EXZ61_RS03215	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
EXZ61_RS03220	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
EXZ61_RS03225	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
EXZ61_RS03230	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
EXZ61_RS03235	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
EXZ61_RS03240	ENOG4105VPB	50S ribosomal protein L30
EXZ61_RS03245	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
EXZ61_RS03250	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
EXZ61_RS03255	ENOG41067V7	50S ribosomal protein L36
EXZ61_RS03260	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EXZ61_RS03265	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
EXZ61_RS03270	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
EXZ61_RS03275	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
EXZ61_RS03280	ENOG4108ZT0	50S ribosomal protein l17
EXZ61_RS03305	ENOG4106KED	esterase YpfH
EXZ61_RS03315	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
EXZ61_RS03320	ENOG4108WKG	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
EXZ61_RS03325	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
EXZ61_RS03330	ENOG4105CQM	Urea amidohydrolase subunit alpha
EXZ61_RS03335	ENOG4105KI2	Urea amidohydrolase subunit beta
EXZ61_RS03345	ENOG4108YZ9	Urea amidohydrolase subunit gamma
EXZ61_RS03350	ENOG4105BZU	Histidine kinase
EXZ61_RS03355	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
EXZ61_RS03370	ENOG4108YYC	ycei family
EXZ61_RS03375	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
EXZ61_RS03380	ENOG4105DR4	Methyltransferase
EXZ61_RS03385	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
EXZ61_RS03400	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
EXZ61_RS03455	ENOG4105CHR	reductase
EXZ61_RS03480	ENOG4107RM6	sulfurtransferase
EXZ61_RS03485	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
EXZ61_RS03490	ENOG4105C32	Amino acid ABC transporter (Permease)
EXZ61_RS03500	ENOG4105C0Z	ABC transporter
EXZ61_RS03505	ENOG4108IV0	ABC, transporter
EXZ61_RS03510	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
EXZ61_RS03515	ENOG4108UQS	dipeptidase
EXZ61_RS03525	ENOG4107QWB	Ornithine cyclodeaminase
EXZ61_RS03535	ENOG4105EW9	transcriptional regulator AsnC family
EXZ61_RS03540	ENOG4107XM9	(LipO)protein
EXZ61_RS03550	ENOG4105C26	Dehydrogenase
EXZ61_RS03565	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
EXZ61_RS03600	ENOG4105BZU	Histidine kinase
EXZ61_RS03605	ENOG4108HRK	Histidine kinase
EXZ61_RS03610	ENOG4108VAC	response regulator
EXZ61_RS03615	ENOG4107QPD	alcohol dehydrogenase
EXZ61_RS03620	ENOG4105C4W	S-formylglutathione hydrolase
EXZ61_RS03630	ENOG4105BZU	Histidine kinase
EXZ61_RS03635	ENOG4105D9P	serine threonine protein kinase
EXZ61_RS03645	ENOG4105EAM	Na Pi-cotransporter
EXZ61_RS03665	ENOG4107S78	Band 7 protein
EXZ61_RS03670	ENOG4105CC0	LysR family Transcriptional regulator
EXZ61_RS03675	ENOG41060W2	glyoxylate carboligase
EXZ61_RS03680	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
EXZ61_RS03685	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
EXZ61_RS03690	ENOG4105CA9	Pyruvate kinase
EXZ61_RS03695	ENOG4105E08	Glycoside hydrolase, family 9
EXZ61_RS03705	ENOG4105VT2	5-hydroxyisourate hydrolase
EXZ61_RS03710	ENOG4107YCY	Transcriptional regulator
EXZ61_RS03720	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
EXZ61_RS03725	ENOG4105C6K	Malic enzyme
EXZ61_RS03735	ENOG4105DXI	Major Facilitator superfamily
EXZ61_RS03740	ENOG4105BZU	Histidine kinase
EXZ61_RS03745	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
EXZ61_RS03750	ENOG4108WQI	RNA Polymerase
EXZ61_RS03755	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
EXZ61_RS03760	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
EXZ61_RS03775	ENOG4105D78	K07001 NTE family protein
EXZ61_RS03785	ENOG4105DJV	ribulose-phosphate 3-epimerase
EXZ61_RS03790	ENOG4105NWN	ApaG protein
EXZ61_RS03795	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
EXZ61_RS03830	ENOG4105MRD	Phage derived protein Gp49-like (DUF891)
EXZ61_RS03845	ENOG4105GZI	Transcriptional regulator
EXZ61_RS03850	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
EXZ61_RS03860	ENOG4105CHU	acetyl-coa acetyltransferase
EXZ61_RS03875	ENOG4105E27	serine threonine protein kinase
EXZ61_RS03885	ENOG4108V1T	peptidylprolyl cis-trans isomerase
EXZ61_RS03890	ENOG4108JQ7	(ABC) transporter
EXZ61_RS03895	ENOG4105C3U	ABC transporter
EXZ61_RS03900	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
EXZ61_RS03905	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
EXZ61_RS03910	ENOG4108J59	Extracellular solute-binding protein, family 5
EXZ61_RS03915	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
EXZ61_RS03930	ENOG4105FE9	pseudouridine synthase
EXZ61_RS03970	ENOG4107YJ4	chain length determinant protein
EXZ61_RS04000	ENOG4105IJJ	transcriptional regulator, crp fnr family
EXZ61_RS04010	ENOG4105C0Z	ABC transporter
EXZ61_RS04015	ENOG4105C32	Amino acid ABC transporter (Permease)
EXZ61_RS04030	ENOG4108IV0	ABC, transporter
EXZ61_RS04035	ENOG4105DZS	Phenylacetate-CoA ligase
EXZ61_RS04090	ENOG4105CAS	nag kinase
EXZ61_RS04095	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
EXZ61_RS04105	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
EXZ61_RS04115	ENOG4105CSU	acyl-Coa dehydrogenase
EXZ61_RS04135	ENOG4105CHU	acetyl-coa acetyltransferase
EXZ61_RS04150	ENOG41060WC	Enoyl-CoA hydratase
EXZ61_RS04155	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
EXZ61_RS04195	ENOG4105C1G	acyl-Coa dehydrogenase
EXZ61_RS04200	ENOG4108VUY	thioesterase Superfamily protein
EXZ61_RS04205	ENOG4105CDY	transcriptional regulatory protein
EXZ61_RS04215	ENOG4105BZU	Histidine kinase
EXZ61_RS04225	ENOG4108S4H	thioesterase Superfamily protein
EXZ61_RS04260	ENOG4105CP9	extracellular ligand-binding receptor
EXZ61_RS04270	ENOG4108IV0	ABC, transporter
EXZ61_RS04275	ENOG4105C0Z	ABC transporter
EXZ61_RS04280	ENOG41071MT	Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane
EXZ61_RS04285	ENOG4105C32	Amino acid ABC transporter (Permease)
EXZ61_RS04290	ENOG4105BZU	Histidine kinase
EXZ61_RS04295	ENOG4105NAU	thioesterase Superfamily protein
EXZ61_RS04300	ENOG4108JJ7	ABC transporter
EXZ61_RS04305	ENOG4105BZU	Histidine kinase
EXZ61_RS04310	ENOG4107R6F	Alpha Beta Hydrolase Fold protein
EXZ61_RS04325	ENOG41086D8	Transcriptional regulator
EXZ61_RS04355	ENOG410908U	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
EXZ61_RS04360	ENOG41061WM	D-Alanyl-D-Alanine
EXZ61_RS04365	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
EXZ61_RS04370	ENOG4105C26	Dehydrogenase
EXZ61_RS04380	ENOG4105VUF	Transcriptional regulator
EXZ61_RS04390	ENOG4105BZU	Histidine kinase
EXZ61_RS04395	ENOG4105EQ2	LysR family Transcriptional regulator
EXZ61_RS04400	ENOG4107RP9	extracellular solute-binding protein, family 3
EXZ61_RS04405	ENOG4105EKE	dihydroorotase
EXZ61_RS04415	ENOG4105D0M	Protease HtpX homolog
EXZ61_RS04420	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
EXZ61_RS04430	ENOG410829K	Lysine exporter protein (Lyse ygga)
EXZ61_RS04440	ENOG4105D7Q	type ii secretion system
EXZ61_RS04445	ENOG4107QHF	type ii secretion system protein e
EXZ61_RS04450	ENOG4105GVR	general secretion pathway protein D
EXZ61_RS04485	ENOG4105X5Z	General secretion pathway protein I
EXZ61_RS04495	ENOG4108VAU	general secretion pathway protein G
EXZ61_RS04510	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
EXZ61_RS04520	ENOG4105DZ0	fad dependent oxidoreductase
EXZ61_RS04530	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
EXZ61_RS04550	ENOG4105C2X	Arabinose 5-phosphate isomerase
EXZ61_RS04570	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
EXZ61_RS04580	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
EXZ61_RS04585	ENOG4105C8Q	Methyl-accepting chemotaxis
EXZ61_RS04590	ENOG4105DR4	Methyltransferase
EXZ61_RS04595	ENOG4105CKI	cobalamin synthesis protein
EXZ61_RS04610	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
EXZ61_RS04615	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
EXZ61_RS04620	ENOG4108V6E	Cell division protein mraZ
EXZ61_RS04625	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
EXZ61_RS04640	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
EXZ61_RS04645	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
EXZ61_RS04650	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
EXZ61_RS04655	ENOG4105CNI	cell division protein FtsW
EXZ61_RS04660	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
EXZ61_RS04665	ENOG4105DFU	Cell wall formation (By similarity)
EXZ61_RS04670	ENOG4105CPF	Cell wall formation (By similarity)
EXZ61_RS04675	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
EXZ61_RS04680	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
EXZ61_RS04685	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
EXZ61_RS04690	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
EXZ61_RS04695	ENOG4105D49	3-dehydroquinate synthase
EXZ61_RS04700	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
EXZ61_RS04735	ENOG4105DHJ	ABC, transporter
EXZ61_RS04740	ENOG4105CY3	ABC transporter, permease
EXZ61_RS04745	ENOG4107PE3	Mammalian cell entry related domain protein
EXZ61_RS04765	ENOG4105DA5	(ABC) transporter
EXZ61_RS04770	ENOG4105E3A	(ABC) transporter
EXZ61_RS04775	ENOG4105VFK	BolA family
EXZ61_RS04780	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
EXZ61_RS04785	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
EXZ61_RS04800	ENOG4106H78	methyltransferase
EXZ61_RS04805	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
EXZ61_RS04815	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
EXZ61_RS04825	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
EXZ61_RS04830	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
EXZ61_RS04835	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
EXZ61_RS04845	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
EXZ61_RS04860	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
EXZ61_RS04870	ENOG4105CEN	a g-specific adenine glycosylase
EXZ61_RS04875	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
EXZ61_RS04880	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
EXZ61_RS04885	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
EXZ61_RS04890	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
EXZ61_RS04900	ENOG4108KU3	Integrase
EXZ61_RS04940	ENOG4108Z6Z	Transcriptional regulator
EXZ61_RS04950	ENOG4107QX3	carboxylase
EXZ61_RS04955	ENOG4105C1G	acyl-Coa dehydrogenase
EXZ61_RS04970	ENOG4105DE9	3-keto-5-aminohexanoate cleavage enzyme
EXZ61_RS04980	ENOG4108RRZ	Transcription elongation factor GreB
EXZ61_RS04985	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
EXZ61_RS04990	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
EXZ61_RS04995	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
EXZ61_RS05000	ENOG4105DSJ	YicC domain protein
EXZ61_RS05070	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
EXZ61_RS05090	ENOG4105CNN	ABC, transporter
EXZ61_RS05105	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
EXZ61_RS05115	ENOG4105DH8	myo-inositol catabolism
EXZ61_RS05120	ENOG4105C26	Dehydrogenase
EXZ61_RS05130	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
EXZ61_RS05155	ENOG4105HEI	LysR family (Transcriptional regulator
EXZ61_RS05170	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
EXZ61_RS05175	ENOG4108594	Permease of the drug metabolite transporter
EXZ61_RS05185	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
EXZ61_RS05190	ENOG4105KNE	Phosphatidate cytidylyltransferase
EXZ61_RS05215	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
EXZ61_RS05220	ENOG4105IPS	esterase
EXZ61_RS05225	ENOG4105CNI	cell division protein FtsW
EXZ61_RS05230	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
EXZ61_RS05235	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
EXZ61_RS05240	ENOG4105DFU	Cell wall formation (By similarity)
EXZ61_RS05250	ENOG4107QX9	Thiol disulfide interChange protein
EXZ61_RS05255	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
EXZ61_RS05260	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
EXZ61_RS05265	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
EXZ61_RS05280	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
EXZ61_RS05285	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
EXZ61_RS05295	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
EXZ61_RS05300	ENOG4107TUY	Histidine kinase
EXZ61_RS05310	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EXZ61_RS05315	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
EXZ61_RS05320	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
EXZ61_RS05340	ENOG4105E39	Enoyl-CoA hydratase
EXZ61_RS05355	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
EXZ61_RS05370	ENOG4105C3G	gtp-binding protein
EXZ61_RS05375	ENOG4105W39	Membrane
EXZ61_RS05380	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
EXZ61_RS05385	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
EXZ61_RS05390	ENOG4105DC1	bifunctional purine biosynthesis protein purh
EXZ61_RS05395	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
EXZ61_RS05400	ENOG4105CSA	Coproporphyrinogen iii oxidase
EXZ61_RS05455	ENOG4105CVR	type I restriction-modification system
EXZ61_RS05460	ENOG4105EKX	Restriction modification system DNA (Specificity
EXZ61_RS05465	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
EXZ61_RS05465	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
EXZ61_RS05475	ENOG4105DZR	Type I site-specific deoxyribonuclease
EXZ61_RS05510	ENOG41066YJ	Beta-lactamase
EXZ61_RS05535	ENOG4108HW4	amino acid AbC transporter
EXZ61_RS05540	ENOG4106PMH	Extracellular solute-binding protein family 3
EXZ61_RS05545	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
EXZ61_RS05560	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
EXZ61_RS05585	ENOG4105E70	isomerase
EXZ61_RS05590	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
EXZ61_RS05595	ENOG4105C6Q	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
EXZ61_RS05600	ENOG4105CE4	GlcNAc 6-P deacetylase
EXZ61_RS05610	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
EXZ61_RS05630	ENOG4105DND	Transcriptional regulator
EXZ61_RS05640	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
EXZ61_RS05660	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
EXZ61_RS05690	ENOG4105UYK	outer membrane protein a
EXZ61_RS05720	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
EXZ61_RS05735	ENOG4108I6A	alcohol dehydrogenase
EXZ61_RS05745	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
EXZ61_RS05755	ENOG4105BZU	Histidine kinase
EXZ61_RS05760	ENOG4105CSR	polyphosphate kinase 2
EXZ61_RS05770	ENOG4105DG7	nitrate ABC transporter
EXZ61_RS05780	ENOG4107Z6I	Thiamine biosynthesis protein
EXZ61_RS05790	ENOG4107YCY	Transcriptional regulator
EXZ61_RS05800	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
EXZ61_RS05805	ENOG4105BZU	Histidine kinase
EXZ61_RS05810	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
EXZ61_RS05815	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
EXZ61_RS05820	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
EXZ61_RS05825	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
EXZ61_RS05840	ENOG4107T6V	glycerophosphoryl diester phosphodiesterase
EXZ61_RS05845	ENOG4108IJ9	(ABC) transporter
EXZ61_RS05860	ENOG4105BZ7	extracellular solute-binding protein family 1
EXZ61_RS05875	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
EXZ61_RS05890	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
EXZ61_RS05905	ENOG4105C9M	aspartyl-trna synthetase
EXZ61_RS05910	ENOG4108TIT	dATP pyrophosphohydrolase
EXZ61_RS05920	ENOG4105DZQ	phospholipase D Transphosphatidylase
EXZ61_RS05925	ENOG4105EUJ	GTP cyclohydrolase i
EXZ61_RS05955	ENOG4105D06	uba thif-type nad fad binding protein
EXZ61_RS05960	ENOG4105CN1	protease
EXZ61_RS05965	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
EXZ61_RS05970	ENOG4107YZP	Rhodanese domain protein
EXZ61_RS05980	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
EXZ61_RS05985	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
EXZ61_RS06000	ENOG4105BZ1	(ABC) transporter
EXZ61_RS06010	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
EXZ61_RS06015	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
EXZ61_RS06030	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
EXZ61_RS06035	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
EXZ61_RS06060	ENOG4105C8Q	Methyl-accepting chemotaxis
EXZ61_RS06075	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
EXZ61_RS06080	ENOG4105CYM	Glutathione S-transferase
EXZ61_RS06140	ENOG4108IYU	L-aspartate oxidase
EXZ61_RS06150	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
EXZ61_RS06170	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
EXZ61_RS06180	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
EXZ61_RS06185	ENOG4105CV6	ABC transporter, permease
EXZ61_RS06195	ENOG4105F8J	Adenylate Guanylate cyclase
EXZ61_RS06220	ENOG4105W5Q	DNA repair protein (RadC
EXZ61_RS06245	ENOG4105W5Q	DNA repair protein (RadC
EXZ61_RS06250	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
EXZ61_RS06255	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
EXZ61_RS06260	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
EXZ61_RS06285	ENOG4105FR1	rard protein
EXZ61_RS06290	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
EXZ61_RS06295	ENOG4105ETT	transcriptional Regulator, LysR family
EXZ61_RS06300	ENOG4105DFH	Transport of potassium into the cell (By similarity)
EXZ61_RS06305	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
EXZ61_RS06310	ENOG4105C08	Histidine kinase
EXZ61_RS06320	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
EXZ61_RS06330	ENOG4105CTX	dehydratase
EXZ61_RS06335	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
EXZ61_RS06340	ENOG410835K	Tripartite ATP-Independent Periplasmic transporter DctQ
EXZ61_RS06345	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
EXZ61_RS06355	ENOG4105E9Z	Nad-dependent epimerase dehydratase
EXZ61_RS06360	ENOG4105JXH	GntR family transcriptional regulator
EXZ61_RS06365	ENOG4105EQX	glucarate dehydratase
EXZ61_RS06370	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
EXZ61_RS06390	ENOG4108WYP	Transcriptional regulator
EXZ61_RS06395	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
EXZ61_RS06400	ENOG4105CFQ	glutamine synthetase
EXZ61_RS06425	ENOG4105C7W	Xanthine dehydrogenase
EXZ61_RS06440	ENOG4108JQ9	ABC transporter
EXZ61_RS06445	ENOG4105UIB	(ABC) transporter
EXZ61_RS06460	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
EXZ61_RS06465	ENOG4107QUY	Guanine deaminase
EXZ61_RS06470	ENOG4105DHP	deoxycytidine triphosphate deaminase
EXZ61_RS06475	ENOG4108ESY	Metal dependent phosphohydrolase
EXZ61_RS06480	ENOG4105C1J	atp-dependent rna helicase
EXZ61_RS06485	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
EXZ61_RS06495	ENOG4107S90	membrAne
EXZ61_RS06515	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EXZ61_RS06520	ENOG4105CD8	aminopeptidase N
EXZ61_RS06525	ENOG4107VXZ	Hydrolase
EXZ61_RS06535	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EXZ61_RS06540	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
EXZ61_RS06545	ENOG4107QKW	extracellular solute-binding protein family 1
EXZ61_RS06555	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
EXZ61_RS06560	ENOG4108ES0	acetoacetyl-CoA synthetase
EXZ61_RS06585	ENOG4105CPC	Aldo Keto reductase
EXZ61_RS06595	ENOG4108Z66	YbaK ebsC protein
EXZ61_RS06600	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
EXZ61_RS06615	ENOG4108VPT	UPF0234 protein
EXZ61_RS06620	ENOG4105D4A	Cell wall formation (By similarity)
EXZ61_RS06625	ENOG4105BZU	Histidine kinase
EXZ61_RS06635	ENOG4105CDH	Citrulline--aspartate ligase
EXZ61_RS06640	ENOG4105NBK	UPF0345 protein
EXZ61_RS06645	ENOG4105KUZ	arsenate reductase
EXZ61_RS06650	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
EXZ61_RS06660	ENOG4105E96	Colicin v production protein
EXZ61_RS06665	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
EXZ61_RS06670	ENOG4105C28	cystathionine
EXZ61_RS06675	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
EXZ61_RS06695	ENOG4107RT3	EamA-like transporter family
EXZ61_RS06710	ENOG4107QKV	phosphomannomutase
EXZ61_RS06715	ENOG4105D16	lipopolysaccharide heptosyltransferase i
EXZ61_RS06720	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
EXZ61_RS06725	ENOG4105DFG	type I secretion outer membrane protein
EXZ61_RS06735	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
EXZ61_RS06750	ENOG4108R86	Transcriptional regulator
EXZ61_RS06760	ENOG4108XM1	transcriptional regulator AsnC family
EXZ61_RS06765	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
EXZ61_RS06775	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
EXZ61_RS06780	ENOG4105K8N	protein family UPF0079, ATPase
EXZ61_RS06785	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
EXZ61_RS06805	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
EXZ61_RS06810	ENOG4105D58	Diguanylate phosphodiesterase
EXZ61_RS06815	ENOG4105ED9	Protein of unknown function (DUF455)
EXZ61_RS06820	ENOG4108Z0R	Transferase
EXZ61_RS06825	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
EXZ61_RS06835	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
EXZ61_RS06840	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
EXZ61_RS06845	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
EXZ61_RS06850	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
EXZ61_RS06855	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
EXZ61_RS06860	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
EXZ61_RS06865	ENOG4108YZY	peptidylprolyl cis-trans isomerase
EXZ61_RS06870	ENOG4105EZE	Cupin 4 family protein
EXZ61_RS06880	ENOG4105GJM	(LipO)protein
EXZ61_RS06885	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
EXZ61_RS06905	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
EXZ61_RS06910	ENOG4105E4C	Lytic transglycosylase catalytic
EXZ61_RS06915	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
EXZ61_RS06920	ENOG4105NI8	Cytosine-specific methyltransferase
EXZ61_RS06940	ENOG4108J2R	molybdopterin oxidoreductase
EXZ61_RS06950	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
EXZ61_RS06955	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
EXZ61_RS06960	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
EXZ61_RS06965	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
EXZ61_RS06970	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
EXZ61_RS07000	ENOG4105FDP	GntR family transcriptional regulator
EXZ61_RS07005	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
EXZ61_RS07010	ENOG4107QM2	Aldo Keto reductase
EXZ61_RS07015	ENOG4105MXW	flavin reductase domain protein, FMN-binding
EXZ61_RS07030	ENOG4105DRS	transport system, permease
EXZ61_RS07045	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
EXZ61_RS07050	ENOG4105CPQ	Dehydrogenase
EXZ61_RS07065	ENOG4105CS6	Rhs element vgr protein
EXZ61_RS07085	ENOG4105K2J	Transcriptional regulator
EXZ61_RS07090	ENOG4105MSY	salicylate hydroxylase
EXZ61_RS07100	ENOG4105C5W	Aldolase
EXZ61_RS07110	ENOG4105E8R	UPF0173 metal-dependent hydrolase
EXZ61_RS07125	ENOG4105CSV	Glutaminase
EXZ61_RS07135	ENOG4105BZU	Histidine kinase
EXZ61_RS07145	ENOG410829K	Lysine exporter protein (Lyse ygga)
EXZ61_RS07150	ENOG4105BZU	Histidine kinase
EXZ61_RS07165	ENOG41082W1	Cupin 2, conserved barrel domain protein
EXZ61_RS07180	ENOG4105E09	nadh pyrophosphatase
EXZ61_RS07190	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
EXZ61_RS07210	ENOG4105DBV	ornithine carbamoyltransferase
EXZ61_RS07215	ENOG4105C8Y	Acetylornithine aminotransferase
EXZ61_RS07225	ENOG41082GY	Binds directly to 16S ribosomal RNA (By similarity)
EXZ61_RS07230	ENOG4105CJR	Integral membrane protein (MviN
EXZ61_RS07235	ENOG41063JG	Transcriptional regulator
EXZ61_RS07245	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
EXZ61_RS07250	ENOG4105C02	permease
EXZ61_RS07255	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
EXZ61_RS07265	ENOG4105DJ0	Poly(A) Polymerase
EXZ61_RS07275	ENOG4105C8Q	Methyl-accepting chemotaxis
EXZ61_RS07280	ENOG4105BZU	Histidine kinase
EXZ61_RS07285	ENOG4105ETT	transcriptional Regulator, LysR family
EXZ61_RS07290	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
EXZ61_RS07295	ENOG4105CXK	mandelate racemase muconate lactonizing
EXZ61_RS07300	ENOG4105C26	Dehydrogenase
EXZ61_RS07305	ENOG4108IJ7	Glycine betaine
EXZ61_RS07310	ENOG4108HQS	Glycine betaine
EXZ61_RS07320	ENOG4105CPC	Aldo Keto reductase
EXZ61_RS07330	ENOG4105C26	Dehydrogenase
EXZ61_RS07345	ENOG4105BZJ	Electron transfer flavoprotein
EXZ61_RS07350	ENOG4105C10	Electron transfer flavoprotein
EXZ61_RS07355	ENOG4105CSU	acyl-Coa dehydrogenase
EXZ61_RS07370	ENOG4105C72	UPF0176 protein
EXZ61_RS07375	ENOG4105CY0	Metallo-Beta-Lactamase
EXZ61_RS07380	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
EXZ61_RS07385	ENOG4105CFG	Acts as a chaperone (By similarity)
EXZ61_RS07390	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EXZ61_RS07395	ENOG4108V1T	peptidylprolyl cis-trans isomerase
EXZ61_RS07410	ENOG4105E2X	shikimate dehydrogenase
EXZ61_RS07420	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
EXZ61_RS07425	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
EXZ61_RS07430	ENOG4108UNC	
EXZ61_RS07435	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
EXZ61_RS07440	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
EXZ61_RS07445	ENOG4105CUJ	penicillin amidase
EXZ61_RS07450	ENOG4107S11	squalene-associated FAD-dependent desaturase
EXZ61_RS07455	ENOG4105FE1	phytoene synthase
EXZ61_RS07470	ENOG4105BZS	acriflavin resistance protein
EXZ61_RS07480	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
EXZ61_RS07485	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
EXZ61_RS07490	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
EXZ61_RS07495	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
EXZ61_RS07565	ENOG4105CPI	Metal Dependent Phosphohydrolase
EXZ61_RS07570	ENOG4105C1G	acyl-Coa dehydrogenase
EXZ61_RS07585	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
EXZ61_RS07595	ENOG4105C5I	Dehydrogenase
EXZ61_RS07605	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
EXZ61_RS07610	ENOG4105HDK	L-asparaginase
EXZ61_RS07615	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
EXZ61_RS07620	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
EXZ61_RS07625	ENOG4105W49	UPF0434 protein
EXZ61_RS07630	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
EXZ61_RS07635	ENOG4108ZZF	transport protein (ExbD)
EXZ61_RS07645	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
EXZ61_RS07650	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
EXZ61_RS07680	ENOG4105DRR	Transcriptional regulator, GntR family
EXZ61_RS07695	ENOG4105DJT	lAO AO transport system ATPase
EXZ61_RS07705	ENOG4107QX3	carboxylase
EXZ61_RS07720	ENOG4108R3D	Electron transport complex
EXZ61_RS07740	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
EXZ61_RS07745	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
EXZ61_RS07760	ENOG4105CGF	Aromatic amino acid aminotransferase
EXZ61_RS07765	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
EXZ61_RS07775	ENOG4105EA8	2-Nitropropane dioxygenase
EXZ61_RS07780	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
EXZ61_RS07800	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
EXZ61_RS07810	ENOG4107104	thymidine kinase
EXZ61_RS07815	ENOG4108WIQ	phosphoesterase PA-phosphatase related protein
EXZ61_RS07835	ENOG4105RD8	TRAP dicarboxylate transporter
EXZ61_RS07845	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
EXZ61_RS07860	ENOG41061CK	Antibiotic biosynthesis monooxygenase
EXZ61_RS07865	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
EXZ61_RS07875	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
EXZ61_RS07880	ENOG4105CHU	acetyl-coa acetyltransferase
EXZ61_RS07885	ENOG4105CHR	reductase
EXZ61_RS07895	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
EXZ61_RS07900	ENOG4105BZU	Histidine kinase
EXZ61_RS07915	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
EXZ61_RS07925	ENOG4108YZT	Adenosylcobinamide kinase
EXZ61_RS07935	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
EXZ61_RS07940	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
EXZ61_RS07955	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
EXZ61_RS07965	ENOG4105EHG	Permease protein
EXZ61_RS07970	ENOG4107QRP	cobalamin biosynthesis protein CobW
EXZ61_RS07975	ENOG4105CTK	cobaltochelatase, cobn subunit
EXZ61_RS07980	ENOG4105EET	magnesium chelatase
EXZ61_RS08040	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
EXZ61_RS08055	ENOG4105QUC	reductase
EXZ61_RS08070	ENOG41081F0	Precorrin-8x methylmutase
EXZ61_RS08080	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
EXZ61_RS08085	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
EXZ61_RS08090	ENOG4105CIH	Imidazole acetol-phosphate transaminase
EXZ61_RS08100	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
EXZ61_RS08105	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
EXZ61_RS08110	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
EXZ61_RS08120	ENOG4108HU6	Metal dependent phosphohydrolase
EXZ61_RS08125	ENOG4105CSM	endonuclease III
EXZ61_RS08130	ENOG4108HU6	Metal dependent phosphohydrolase
EXZ61_RS08135	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
EXZ61_RS08140	ENOG4105DEN	Luciferase family
EXZ61_RS08145	ENOG4105VEJ	Heat shock protein
EXZ61_RS08150	ENOG4105DHQ	Histidine kinase
EXZ61_RS08190	ENOG4108SDH	ABC, transporter
EXZ61_RS08195	ENOG4108IUW	ABC transporter
EXZ61_RS08205	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
EXZ61_RS08215	ENOG4105CJ1	ABC, transporter
EXZ61_RS08220	ENOG4107QWP	ABC-2 type transporter
EXZ61_RS08230	ENOG4105C0Z	ABC transporter
EXZ61_RS08235	ENOG4108IV0	ABC, transporter
EXZ61_RS08245	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
EXZ61_RS08260	ENOG4105C2W	permease
EXZ61_RS08270	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
EXZ61_RS08275	ENOG4105C3J	Cysteine desulfurase
EXZ61_RS08280	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
EXZ61_RS08290	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
EXZ61_RS08295	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
EXZ61_RS08300	ENOG4108ZIT	Ferredoxin, 2FE-2S
EXZ61_RS08305	ENOG4107RZZ	dna polymerase iii epsilon subunit
EXZ61_RS08325	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
EXZ61_RS08330	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
EXZ61_RS08335	ENOG4108K5P	(LipO)protein
EXZ61_RS08340	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
EXZ61_RS08345	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
EXZ61_RS08355	ENOG4108MN8	Membrane
EXZ61_RS08360	ENOG4108ZJF	Glcg protein
EXZ61_RS08370	ENOG4105M8F	Biopolymer transport protein exbD tolR
EXZ61_RS08385	ENOG4107E2E	PKHD-type hydroxylase
EXZ61_RS08430	ENOG4108UQY	Iron-storage protein
EXZ61_RS08450	ENOG4105EJ2	Transcriptional regulator
EXZ61_RS08455	ENOG4105EG6	Saccharopine dehydrogenase
EXZ61_RS08460	ENOG4107FW0	short-chain dehydrogenase reductase
EXZ61_RS08470	ENOG4105D05	Receptor
EXZ61_RS08480	ENOG4106QJH	hemin transport protein
EXZ61_RS08490	ENOG4105EHG	Permease protein
EXZ61_RS08495	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
EXZ61_RS08500	ENOG4108M1A	Chitin-binding protein
EXZ61_RS08515	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
EXZ61_RS08525	ENOG4107QN1	sodium solute
EXZ61_RS08530	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
EXZ61_RS08540	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
EXZ61_RS08545	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
EXZ61_RS08550	ENOG4105CDU	Replicative dna helicase
EXZ61_RS08555	ENOG4108IAB	Phoh family
EXZ61_RS08560	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EXZ61_RS08570	ENOG4105CHM	Aminotransferase
EXZ61_RS08575	ENOG4105D6E	homoserine dehydrogenase
EXZ61_RS08585	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
EXZ61_RS08595	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
EXZ61_RS08600	ENOG4108ZAF	Molybdopterin
EXZ61_RS08605	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
EXZ61_RS08615	ENOG4105C0D	helicase
EXZ61_RS08625	ENOG4105M8F	Biopolymer transport protein exbD tolR
EXZ61_RS08630	ENOG4105E02	MotA TolQ exbB proton channel
EXZ61_RS08640	ENOG4107YIM	Involved in the transcription termination process (By similarity)
EXZ61_RS08645	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
EXZ61_RS08650	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
EXZ61_RS08655	ENOG4108R6K	riboflavin synthase, subunit alpha
EXZ61_RS08715	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
EXZ61_RS08720	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
EXZ61_RS08725	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
EXZ61_RS08735	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
EXZ61_RS08755	ENOG4108PPB	Seems to be required for the assembly of the photosystem I complex (By similarity)
EXZ61_RS08760	ENOG4105C8N	cysteinyl-tRNA synthetase
EXZ61_RS08775	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
EXZ61_RS08785	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
EXZ61_RS08790	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
EXZ61_RS08800	ENOG4105EAC	phosphoserine phosphatase
EXZ61_RS08815	ENOG4105BZU	Histidine kinase
EXZ61_RS08820	ENOG4108JA2	transcriptioN-repair coupling factor
EXZ61_RS08825	ENOG4108ECM	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) (By similarity)
EXZ61_RS08830	ENOG4108ECM	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) (By similarity)
EXZ61_RS08835	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
EXZ61_RS08840	ENOG4105E0F	Histidine kinase
EXZ61_RS08860	ENOG4105BZU	Histidine kinase
EXZ61_RS08865	ENOG4105DTD	Dehydrogenase
EXZ61_RS08870	ENOG4107RCM	Releases the N-terminal proline from various substrates (By similarity)
EXZ61_RS08875	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
EXZ61_RS08915	ENOG4108MIW	Induces the synthesis of acid phosphatase (AppA) and several other polypeptides (such as AppBC) during the deceleration phase of growth. It also acts as a transcriptional repressor for one group of proteins that are synthesized preferentially in exponential growth and for one group synthesized only in the stationary phase. Also involved in the stabilization of the sigma stress factor RpoS during stress conditions
EXZ61_RS08920	ENOG4108ETT	Dehydrogenase
EXZ61_RS08940	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
EXZ61_RS08945	ENOG4105D7A	ATP-binding protein
EXZ61_RS08950	ENOG4105CDY	transcriptional regulatory protein
EXZ61_RS08955	ENOG4105C12	Phosphoribosylglycinamide synthetase
EXZ61_RS08965	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
EXZ61_RS08970	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
EXZ61_RS08975	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
EXZ61_RS08980	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
EXZ61_RS08985	ENOG4108Z03	MAF-like protein
EXZ61_RS08990	ENOG4105C03	ribonuclease
EXZ61_RS08995	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
EXZ61_RS09030	ENOG4105BZ1	(ABC) transporter
EXZ61_RS09045	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
EXZ61_RS09050	ENOG4105KCK	Peptidoglycan-associated lipoprotein
EXZ61_RS09060	ENOG4105CUZ	uba thif-type nad fad binding protein
EXZ61_RS09075	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
EXZ61_RS09085	ENOG4105CE9	30S ribosomal protein S2
EXZ61_RS09090	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
EXZ61_RS09095	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
EXZ61_RS09100	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
EXZ61_RS09110	ENOG4105KNE	Phosphatidate cytidylyltransferase
EXZ61_RS09115	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
EXZ61_RS09120	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EXZ61_RS09130	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
EXZ61_RS09135	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
EXZ61_RS09140	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
EXZ61_RS09145	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
EXZ61_RS09150	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
EXZ61_RS09155	ENOG4108RWN	rrna methyltransferase
EXZ61_RS09165	ENOG4108NIW	Leucine export protein LeuE
EXZ61_RS09170	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
EXZ61_RS09175	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
EXZ61_RS09185	ENOG4105HBR	Rna-binding protein
EXZ61_RS09190	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
EXZ61_RS09195	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
EXZ61_RS09200	ENOG4105EEI	dihydropteroate synthase
EXZ61_RS09205	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
EXZ61_RS09220	ENOG4105CAU	Arsenical resistance protein, ArsH
EXZ61_RS09230	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
EXZ61_RS09255	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
EXZ61_RS09275	ENOG4105BZU	Histidine kinase
EXZ61_RS09280	ENOG4105C9X	ppx gppa phosphatase
EXZ61_RS09295	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
EXZ61_RS09300	ENOG4105C8U	phosphate abc transporter
EXZ61_RS09305	ENOG4105E2Z	phosphate ABC transporter (Permease
EXZ61_RS09310	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
EXZ61_RS09320	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
EXZ61_RS09325	ENOG4105BZU	Histidine kinase
EXZ61_RS09335	ENOG4105CAY	ferredoxin--nadp reductase
EXZ61_RS09340	ENOG4108Z4U	Ferredoxin
EXZ61_RS09350	ENOG4105C11	sulfate adenylyltransferase), subunit 2
EXZ61_RS09370	ENOG4107TSN	permease
EXZ61_RS09385	ENOG4108RVA	ribokinase
EXZ61_RS09390	ENOG4105DD7	kinase (PfkB family
EXZ61_RS09395	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
EXZ61_RS09400	ENOG4105DIH	basic membrane
EXZ61_RS09405	ENOG4108JQ9	ABC transporter
EXZ61_RS09410	ENOG4105UIB	(ABC) transporter
EXZ61_RS09425	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
EXZ61_RS09435	ENOG4108Z6B	deaminase
EXZ61_RS09440	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
EXZ61_RS09455	ENOG4105CHM	Aminotransferase
EXZ61_RS09460	ENOG4107R11	Transcriptional regulator
EXZ61_RS09470	ENOG4108K5H	permease YjgP YjgQ family protein
EXZ61_RS09480	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
EXZ61_RS09495	ENOG4105CP9	extracellular ligand-binding receptor
EXZ61_RS09505	ENOG4105BZU	Histidine kinase
EXZ61_RS09510	ENOG4105BZU	Histidine kinase
EXZ61_RS09520	ENOG4105BZU	Histidine kinase
EXZ61_RS09570	ENOG4105CXN	decarboxylase
EXZ61_RS09575	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
EXZ61_RS09580	ENOG4105E43	Extracellular solute-binding protein, family 5
EXZ61_RS09585	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
EXZ61_RS09590	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
EXZ61_RS09595	ENOG4108JQ5	ABC transporter
EXZ61_RS09600	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
EXZ61_RS09605	ENOG4105CHV	Transcription elongation factor NusA
EXZ61_RS09610	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
EXZ61_RS09615	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
EXZ61_RS09620	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
EXZ61_RS09625	ENOG4105CI3	gtp-binding protein typa
EXZ61_RS09635	ENOG4105E39	Enoyl-CoA hydratase
EXZ61_RS09640	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
EXZ61_RS09645	ENOG4108Z1B	Cyclase dehydrase
EXZ61_RS09650	ENOG4105VDB	UPF0125 protein
EXZ61_RS09660	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
EXZ61_RS09665	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
EXZ61_RS09680	ENOG4108EKC	n-acetylglutamate synthase
EXZ61_RS09685	ENOG4105CQ7	ATP-dependent helicase
EXZ61_RS09690	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
EXZ61_RS09695	ENOG4105BZU	Histidine kinase
EXZ61_RS09700	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
EXZ61_RS09720	ENOG4105D5U	fad dependent oxidoreductase
EXZ61_RS09725	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
EXZ61_RS09730	ENOG4105E66	phosphoriboisomerase A
EXZ61_RS09740	ENOG4105DGW	oligopeptidase A
EXZ61_RS09745	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
EXZ61_RS09750	ENOG4108ZXC	Two component transcriptional regulator, luxr family
EXZ61_RS09755	ENOG4105BZU	Histidine kinase
EXZ61_RS09760	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
EXZ61_RS09765	ENOG4107QSN	dihydrolipoamide acetyltransferase
EXZ61_RS09770	ENOG4107QN2	dihydrolipoyl dehydrogenase
EXZ61_RS09795	ENOG4105CS6	Rhs element vgr protein
EXZ61_RS09805	ENOG4105K64	Glycosyl transferase, family 2
EXZ61_RS09855	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
EXZ61_RS09870	ENOG4105CZK	Aspartate kinase
EXZ61_RS09885	ENOG4105XRQ	Xanthine dehydrogenase accessory factor
EXZ61_RS09905	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
EXZ61_RS09910	ENOG4105D8V	Glucose sorbosone dehydrogenase
EXZ61_RS09925	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
EXZ61_RS09930	ENOG4105C3U	ABC transporter
EXZ61_RS09935	ENOG4108JQ7	(ABC) transporter
EXZ61_RS09940	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
EXZ61_RS09950	ENOG4105CBN	LysR family transcriptional regulator
EXZ61_RS09960	ENOG4105DHU	Bile acid
EXZ61_RS09990	ENOG4105BZ1	(ABC) transporter
EXZ61_RS10000	ENOG4105C0A	alcohol dehydrogenase
EXZ61_RS10005	ENOG4105BZU	Histidine kinase
EXZ61_RS10010	ENOG4105WH1	Two component transcriptional regulator luxr family
EXZ61_RS10040	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
EXZ61_RS10045	ENOG4105BZU	Histidine kinase
EXZ61_RS10065	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
EXZ61_RS10080	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
EXZ61_RS10085	ENOG4105K63	Thioredoxin
EXZ61_RS10090	ENOG4105DP0	ferredoxin-NADP reductase
EXZ61_RS10095	ENOG4105DVT	helicase
EXZ61_RS10100	ENOG41069P5	Protein slyX homolog
EXZ61_RS10105	ENOG4105BZU	Histidine kinase
EXZ61_RS10110	ENOG4105D3G	Pseudouridine synthase
EXZ61_RS10115	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
EXZ61_RS10125	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
EXZ61_RS10130	ENOG4108QDE	fad dependent oxidoreductase
EXZ61_RS10135	ENOG4105EQ1	Transcriptional regulator
EXZ61_RS10145	ENOG4108SB3	DoxX Family
EXZ61_RS10160	ENOG4105EUB	pirin domain protein
EXZ61_RS10165	ENOG4105C72	UPF0176 protein
EXZ61_RS10175	ENOG4105C0B	DNA polymerase III (alpha subunit)
EXZ61_RS10185	ENOG4106HNH	Acyl-transferase
EXZ61_RS10190	ENOG4105BZU	Histidine kinase
EXZ61_RS10195	ENOG4108JEH	abc transporter atp-binding protein
EXZ61_RS10210	ENOG4105DSP	amino acid AbC transporter
EXZ61_RS10215	ENOG4105E89	ABC transporter
EXZ61_RS10220	ENOG4105CCT	upf0313 protein
EXZ61_RS10225	ENOG4105ETT	transcriptional Regulator, LysR family
EXZ61_RS10230	ENOG4108EC8	DNA internalization-related competence protein ComEC
EXZ61_RS10245	ENOG4105CVE	Lytic murein transglycosylase
EXZ61_RS10250	ENOG4105F8C	transglutaminase domain-containing protein
EXZ61_RS10260	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
EXZ61_RS10265	ENOG4105DGU	Histone deacetylase
EXZ61_RS10270	ENOG4105EGS	Mechanosensitive ion channel
EXZ61_RS10280	ENOG4105D64	Mechanosensitive ion channel
EXZ61_RS10300	ENOG4105QDK	Flavodoxin
EXZ61_RS10310	ENOG4108RPX	mosc domain containing protein
EXZ61_RS10315	ENOG4105C0A	alcohol dehydrogenase
EXZ61_RS10330	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
EXZ61_RS10335	ENOG4105C2J	ABC transporter
EXZ61_RS10340	ENOG4105CNN	ABC, transporter
EXZ61_RS10350	ENOG4105ERH	Fumarylacetoacetate hydrolase
EXZ61_RS10355	ENOG4105DIA	mandelate racemase muconate lactonizing
EXZ61_RS10365	ENOG4105CHR	reductase
EXZ61_RS10370	ENOG4105QJH	Domain of unknown function (DUF718)
EXZ61_RS10390	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
EXZ61_RS10395	ENOG4105D3Q	Sugar transferase
EXZ61_RS10440	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
EXZ61_RS10455	ENOG4105K64	Glycosyl transferase, family 2
EXZ61_RS10480	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
EXZ61_RS10490	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
EXZ61_RS10525	ENOG4105C01	Dihydroxy-acid dehydratase
EXZ61_RS10530	ENOG4108UHU	Aldolase
EXZ61_RS10545	ENOG4105CMR	udp-glucose 4-epimerase
EXZ61_RS10565	ENOG4105C5H	ABC transporter
EXZ61_RS10570	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
EXZ61_RS10575	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
EXZ61_RS10580	ENOG4105CZX	twitching motility protein
EXZ61_RS10585	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
EXZ61_RS10590	ENOG4107QSS	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli (By similarity)
EXZ61_RS10600	ENOG4105F8J	Adenylate Guanylate cyclase
EXZ61_RS10605	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
EXZ61_RS10615	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
EXZ61_RS10620	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
EXZ61_RS10625	ENOG4105C84	Histidine ammonia-lyase
EXZ61_RS10630	ENOG4105CGP	Urocanate hydratase
EXZ61_RS10635	ENOG4107258	Transcriptional regulator
EXZ61_RS10640	ENOG4105CZE	histidine utilization repressor
EXZ61_RS10650	ENOG4105CI2	imidazolone-5-propionate hydrolase
EXZ61_RS10690	ENOG4108YXU	transcriptional regulator AsnC family
EXZ61_RS10700	ENOG4105KZX	Pterin carbinolamine dehydratase
EXZ61_RS10705	ENOG4105MIR	Phenylalanine 4-monooxygenase
EXZ61_RS10715	ENOG4105DEF	Extracellular solute-binding protein, family 5
EXZ61_RS10720	ENOG4108JQ7	(ABC) transporter
EXZ61_RS10725	ENOG4105C3U	ABC transporter
EXZ61_RS10730	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
EXZ61_RS10735	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
EXZ61_RS10745	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
EXZ61_RS10760	ENOG4105CJP	fad dependent oxidoreductase
EXZ61_RS10770	ENOG4105CFQ	glutamine synthetase
EXZ61_RS10775	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
EXZ61_RS10785	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EXZ61_RS10790	ENOG4105F38	ABC transporter, permease
EXZ61_RS10795	ENOG4105D38	putrescine abc transporter
EXZ61_RS10800	ENOG4105C26	Dehydrogenase
EXZ61_RS10805	ENOG4108JPW	Aminotransferase
EXZ61_RS10815	ENOG4108I9X	Isocitrate lyase
EXZ61_RS10820	ENOG4105C22	threonyL-tRNA synthetase
EXZ61_RS10825	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
EXZ61_RS10830	ENOG4105VJV	50s ribosomal protein L35
EXZ61_RS10835	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
EXZ61_RS10840	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
EXZ61_RS10845	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
EXZ61_RS10850	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
EXZ61_RS10855	ENOG4108XDN	Transcriptional regulator
EXZ61_RS10870	ENOG4105F8V	Hydrolase, tatD family
EXZ61_RS10880	ENOG4107QRG	dna polymerase iii
EXZ61_RS10885	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
EXZ61_RS10890	ENOG4105HHA	aminodeoxychorismate lyase
EXZ61_RS10895	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
EXZ61_RS10900	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
EXZ61_RS10910	ENOG4105C8Q	Methyl-accepting chemotaxis
EXZ61_RS10925	ENOG4105BZM	domain protein
EXZ61_RS10940	ENOG4105CR8	Transcriptional regulator
EXZ61_RS10960	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
EXZ61_RS10965	ENOG41061MV	Arylsulfatase
EXZ61_RS10970	ENOG4105DGU	Histone deacetylase
EXZ61_RS10985	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
EXZ61_RS11020	ENOG4105CSU	acyl-Coa dehydrogenase
EXZ61_RS11030	ENOG4108R85	Short chain dehydrogenase
EXZ61_RS11040	ENOG4105CSU	acyl-Coa dehydrogenase
EXZ61_RS11050	ENOG4105CHU	acetyl-coa acetyltransferase
EXZ61_RS11055	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
EXZ61_RS11065	ENOG4105CNG	UPF0061 protein
EXZ61_RS11070	ENOG4105E0X	reductase
EXZ61_RS11075	ENOG4107835	probably involved in intracellular septation (By similarity)
EXZ61_RS11085	ENOG4107TF3	peptidylprolyl cis-trans isomerase
EXZ61_RS11135	ENOG4105CS6	Rhs element vgr protein
EXZ61_RS11165	ENOG4105UYK	outer membrane protein a
EXZ61_RS11200	ENOG4105CS6	Rhs element vgr protein
EXZ61_RS11220	ENOG4108WC9	type VI secretion system effector, hcp1 family
EXZ61_RS11235	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
EXZ61_RS11250	ENOG4108ETH	Formylglycinamide ribotide synthetase
EXZ61_RS11255	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
EXZ61_RS11265	ENOG4105C1G	acyl-Coa dehydrogenase
EXZ61_RS11270	ENOG4105CHU	acetyl-coa acetyltransferase
EXZ61_RS11275	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
EXZ61_RS11280	ENOG4107S9D	Alpha beta hydrolase
EXZ61_RS11290	ENOG4105BZU	Histidine kinase
EXZ61_RS11305	ENOG4105CAH	Chromate
EXZ61_RS11310	ENOG4108PCN	EamA-like transporter family
EXZ61_RS11330	ENOG4105C2N	RNA methyltransferase TrmH family group 3
EXZ61_RS11335	ENOG4108I0Y	(ABC) transporter
EXZ61_RS11340	ENOG4108UJV	acyl-CoA thioesterase i
EXZ61_RS11360	ENOG4105C28	cystathionine
EXZ61_RS11370	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
EXZ61_RS11375	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
EXZ61_RS11385	ENOG4105EPW	hflc protein
EXZ61_RS11390	ENOG4107QJR	hflk protein
EXZ61_RS11395	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
EXZ61_RS11400	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
EXZ61_RS11405	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
EXZ61_RS11410	ENOG4105DZG	Dehydrogenase
EXZ61_RS11420	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
EXZ61_RS11435	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
EXZ61_RS11440	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
EXZ61_RS11445	ENOG4105FE9	pseudouridine synthase
EXZ61_RS11450	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
EXZ61_RS11455	ENOG4105C34	Pseudouridine synthase
EXZ61_RS11465	ENOG4105DVT	helicase
EXZ61_RS11485	ENOG4105D6Z	AFG1 family ATPase
EXZ61_RS11490	ENOG4107QN2	dihydrolipoyl dehydrogenase
EXZ61_RS11495	ENOG4105C7S	Dehydrogenase
EXZ61_RS11500	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
EXZ61_RS11505	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
EXZ61_RS11515	ENOG4105K4H	Nlp p60 protein
EXZ61_RS11530	ENOG4105C1J	atp-dependent rna helicase
EXZ61_RS11535	ENOG4105BZU	Histidine kinase
EXZ61_RS11545	ENOG4105EGI	Transcriptional regulator
EXZ61_RS11550	ENOG4107TYH	extracellular solute-binding protein family 1
EXZ61_RS11555	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EXZ61_RS11560	ENOG4105D81	ABC transporter, permease
EXZ61_RS11565	ENOG4105NRK	Binding-protein-dependent transport systems, inner membrane component
EXZ61_RS11570	ENOG4105C26	Dehydrogenase
EXZ61_RS11575	ENOG4105C8Q	Methyl-accepting chemotaxis
EXZ61_RS11580	ENOG4105BZU	Histidine kinase
EXZ61_RS11585	ENOG4105BZU	Histidine kinase
EXZ61_RS11590	ENOG4108NEV	two component transcriptional regulator, LytTR family
EXZ61_RS11600	ENOG4105EWK	phytoene
EXZ61_RS11620	ENOG4106IPI	cyclase, family
EXZ61_RS11635	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
EXZ61_RS11640	ENOG4105C3U	ABC transporter
EXZ61_RS11670	ENOG4106NV8	metalloendopeptidase activity
EXZ61_RS11680	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
EXZ61_RS11690	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
EXZ61_RS11695	ENOG4108JP0	extracellular solute-binding protein family 1
EXZ61_RS11725	ENOG4105ETE	Transcriptional regulator (LacI family
EXZ61_RS11730	ENOG4105C1G	acyl-Coa dehydrogenase
EXZ61_RS11735	ENOG4105ETT	transcriptional Regulator, LysR family
EXZ61_RS11750	ENOG4105CSU	acyl-Coa dehydrogenase
EXZ61_RS11765	ENOG4105CHR	reductase
EXZ61_RS11775	ENOG41067TZ	transcriptional regulator, MarR family
EXZ61_RS11785	ENOG4105CW7	secretion protein, HlyD family
EXZ61_RS11790	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
EXZ61_RS11795	ENOG4105KG3	cytidine deaminase
EXZ61_RS11810	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
EXZ61_RS11820	ENOG4107QNJ	CoA-transferase subunit B
EXZ61_RS11840	ENOG4105EXG	Transcriptional regulator
EXZ61_RS11855	ENOG4107QSV	RmuC domain protein
EXZ61_RS11870	ENOG4107RH7	Nicotinate phosphoribosyltransferase
EXZ61_RS11880	ENOG4108WFY	phasin family
EXZ61_RS11885	ENOG4105D78	K07001 NTE family protein
EXZ61_RS11890	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
EXZ61_RS11895	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
EXZ61_RS11900	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
EXZ61_RS11910	ENOG4105D4P	Coproporphyrinogen iii oxidase
EXZ61_RS11915	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
EXZ61_RS11945	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
EXZ61_RS11965	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
EXZ61_RS11970	ENOG4105BZU	Histidine kinase
EXZ61_RS11980	ENOG4105CEY	Amp-dependent synthetase and ligase
EXZ61_RS11990	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
EXZ61_RS11995	ENOG4106NZI	LysR family Transcriptional regulator
EXZ61_RS12000	ENOG4105C01	Dihydroxy-acid dehydratase
EXZ61_RS12010	ENOG4105W2Z	cytochrome C, class I
EXZ61_RS12015	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
EXZ61_RS12020	ENOG4108TEB	UPF0114 protein
EXZ61_RS12030	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
EXZ61_RS12045	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
EXZ61_RS12050	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
EXZ61_RS12055	ENOG4107HP6	Transcriptional regulator
EXZ61_RS12060	ENOG41061WM	D-Alanyl-D-Alanine
EXZ61_RS12065	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
EXZ61_RS12070	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
EXZ61_RS12075	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
EXZ61_RS12080	ENOG4108ZP8	Acetolactate synthase small subunit
EXZ61_RS12085	ENOG4105C7K	acetolactate synthase
EXZ61_RS12110	ENOG41080IJ	Diacylglycerol kinase
EXZ61_RS12115	ENOG4108URH	decarboxylase
EXZ61_RS12125	ENOG4105C4K	Nad synthetase
EXZ61_RS12135	ENOG4105C8Q	Methyl-accepting chemotaxis
EXZ61_RS12140	ENOG4105C8Q	Methyl-accepting chemotaxis
EXZ61_RS12145	ENOG4108V3W	Chemotaxis protein, CheW
EXZ61_RS12150	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
EXZ61_RS12155	ENOG4105F0N	pyrophosphate phospho-hydrolase
EXZ61_RS12165	ENOG4108W5X	Transcriptional Regulator, LuxR family
EXZ61_RS12170	ENOG4105BZU	Histidine kinase
EXZ61_RS12185	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
EXZ61_RS12190	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
EXZ61_RS12195	ENOG4105BZS	acriflavin resistance protein
EXZ61_RS12205	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
EXZ61_RS12215	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
EXZ61_RS12220	ENOG4105E9H	Lytic Murein transglycosylase
EXZ61_RS12230	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
EXZ61_RS12235	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
EXZ61_RS12240	ENOG4107QMP	dna polymerase iii subunits gamma and tau
EXZ61_RS12275	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
EXZ61_RS12285	ENOG4105K63	Thioredoxin
EXZ61_RS12290	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
EXZ61_RS12295	ENOG4105NRA	50s ribosomal protein l31 type b
EXZ61_RS12320	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
EXZ61_RS12340	ENOG4105CHR	reductase
EXZ61_RS12345	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
EXZ61_RS12350	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
EXZ61_RS12355	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
EXZ61_RS12360	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXZ61_RS12365	ENOG4105EJQ	L-serine dehydratase
EXZ61_RS12375	ENOG4105CYM	Glutathione S-transferase
EXZ61_RS12415	ENOG4105CQ2	DNA polymerase
EXZ61_RS12425	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
EXZ61_RS12430	ENOG4105E0C	molybdate abc transporter
EXZ61_RS12435	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
EXZ61_RS12440	ENOG4105F4R	Transcriptional regulator mode
EXZ61_RS12445	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EXZ61_RS12455	ENOG4105DP9	ABC transporter
EXZ61_RS12495	ENOG4105BZ1	(ABC) transporter
EXZ61_RS12510	ENOG4105D82	Glutamate dehydrogenase
EXZ61_RS12530	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
EXZ61_RS12535	ENOG4105C8S	subunit m
EXZ61_RS12540	ENOG4105D65	subunit l
EXZ61_RS12545	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
EXZ61_RS12550	ENOG4105DF2	NADH dehydrogenase subunit j
EXZ61_RS12555	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
EXZ61_RS12560	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
EXZ61_RS12565	ENOG4108IEH	NADH dehydrogenase subunit g
EXZ61_RS12580	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
EXZ61_RS12585	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EXZ61_RS12590	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
EXZ61_RS12595	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EXZ61_RS12605	ENOG4107EJC	Preprotein translocase subunit SecG
EXZ61_RS12610	ENOG4105CP7	Triose-phosphate isomerase
EXZ61_RS12620	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
EXZ61_RS12625	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
EXZ61_RS12635	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
EXZ61_RS12640	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
EXZ61_RS12650	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
EXZ61_RS12655	ENOG4105EB2	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
EXZ61_RS12680	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
EXZ61_RS12695	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EXZ61_RS12700	ENOG4108MTB	glycosyl transferase family
EXZ61_RS12710	ENOG4105CBX	hi0933 family
EXZ61_RS12715	ENOG4105VCC	30S ribosomal protein S21
EXZ61_RS12720	ENOG4105KTH	gatB Yqey
EXZ61_RS12725	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
EXZ61_RS12730	ENOG4105N42	UPF0307 protein
EXZ61_RS12735	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
EXZ61_RS12740	ENOG4105D7W	serine acetyltransferase
EXZ61_RS12750	ENOG4105ECY	inositol monophosphatase
EXZ61_RS12755	ENOG4105BZU	Histidine kinase
EXZ61_RS12770	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
EXZ61_RS12795	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
EXZ61_RS12810	ENOG4108HE4	integrase family
EXZ61_RS12895	ENOG4105C0D	helicase
EXZ61_RS12995	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
EXZ61_RS13010	ENOG4105BZU	Histidine kinase
EXZ61_RS13015	ENOG4105BZU	Histidine kinase
EXZ61_RS13020	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
EXZ61_RS13025	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
EXZ61_RS13030	ENOG4105C19	ABC transporter
EXZ61_RS13050	ENOG4108HRK	Histidine kinase
EXZ61_RS13055	ENOG4108VAC	response regulator
EXZ61_RS13075	ENOG4107R34	abc transporter permease protein
EXZ61_RS13080	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
EXZ61_RS13100	ENOG4105BZU	Histidine kinase
EXZ61_RS13105	ENOG4105CX6	glutaminyL-tRNA synthetase
EXZ61_RS13160	ENOG4105DBI	uridine monophosphokinase
EXZ61_RS13170	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
EXZ61_RS13210	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
EXZ61_RS13290	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
EXZ61_RS13295	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
EXZ61_RS13300	ENOG4105CTD	carboxy-peptidase
EXZ61_RS13305	ENOG4108PZW	LysR family Transcriptional regulator
EXZ61_RS13310	ENOG4105BZU	Histidine kinase
EXZ61_RS13345	ENOG4105CYN	Serine protein kinase
EXZ61_RS13350	ENOG4106AKX	UPF0229 protein
EXZ61_RS13355	ENOG4105ED1	spovr family
EXZ61_RS13365	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
EXZ61_RS13375	ENOG4105D9M	gamma-glutamylcysteine synthetase
EXZ61_RS13385	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
EXZ61_RS13400	ENOG4108JU3	Alkyl hydroperoxide reductase
EXZ61_RS13420	ENOG4107QHF	type ii secretion system protein e
EXZ61_RS13425	ENOG4105I7M	spermidine synthase
EXZ61_RS13430	ENOG4105EYA	deoxyribonuclease
EXZ61_RS13440	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
EXZ61_RS13455	ENOG4105C8Q	Methyl-accepting chemotaxis
EXZ61_RS13460	ENOG4108V3W	Chemotaxis protein, CheW
EXZ61_RS13470	ENOG4108MX5	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity)
EXZ61_RS13475	ENOG4105FDP	GntR family transcriptional regulator
EXZ61_RS13485	ENOG4108JQ7	(ABC) transporter
EXZ61_RS13515	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
EXZ61_RS13520	ENOG41061DF	Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P (By similarity)
EXZ61_RS13530	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
EXZ61_RS13535	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
EXZ61_RS13550	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
EXZ61_RS13560	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
EXZ61_RS13575	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
EXZ61_RS13585	ENOG4105EXG	Transcriptional regulator
EXZ61_RS13595	ENOG4105CPC	Aldo Keto reductase
EXZ61_RS13605	ENOG410904N	short-chain dehydrogenase reductase
EXZ61_RS13615	ENOG4105CHU	acetyl-coa acetyltransferase
EXZ61_RS13640	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
EXZ61_RS13645	ENOG4107QXX	ABC transporter
EXZ61_RS13650	ENOG4105EZ7	amino acid ABC transporter
EXZ61_RS13655	ENOG4105DRP	amino acid AbC transporter
EXZ61_RS13660	ENOG4105CDA	abc transporter atp-binding protein
EXZ61_RS13675	ENOG4105UT3	Methyl-accepting chemotaxis
EXZ61_RS13680	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
EXZ61_RS13685	ENOG4105BZU	Histidine kinase
EXZ61_RS13700	ENOG4105C5H	ABC transporter
EXZ61_RS13710	ENOG4105C1J	atp-dependent rna helicase
EXZ61_RS13755	ENOG4108V1U	phospholipid-binding protein
EXZ61_RS13795	ENOG4105DIK	(ABC) transporter
EXZ61_RS13800	ENOG4105CC5	ABC transporter
EXZ61_RS13805	ENOG4105DSE	periplasmic solute binding protein
EXZ61_RS13840	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
EXZ61_RS13860	ENOG4107R5G	Periplasmic binding protein LacI transcriptional regulator
EXZ61_RS13865	ENOG4105CNN	ABC, transporter
EXZ61_RS13870	ENOG4105C2J	ABC transporter
EXZ61_RS13875	ENOG4105NWF	RbsD or FucU transport
EXZ61_RS13885	ENOG4105EUB	pirin domain protein
EXZ61_RS13890	ENOG4105CC0	LysR family Transcriptional regulator
EXZ61_RS13895	ENOG4105DQR	SNARE associated Golgi
EXZ61_RS13900	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
EXZ61_RS13915	ENOG4108YZN	class I peptide chain release factor
EXZ61_RS13920	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
EXZ61_RS13925	ENOG4105C4M	(Ubiquinol oxidase) subunit I
EXZ61_RS13940	ENOG4108IJ9	(ABC) transporter
EXZ61_RS13945	ENOG41066F8	ROK family
EXZ61_RS13950	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
EXZ61_RS13955	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
EXZ61_RS13960	ENOG4107T3P	ABC, transporter
EXZ61_RS13970	ENOG4107QI1	Mate efflux family protein
EXZ61_RS13975	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
EXZ61_RS13980	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
EXZ61_RS13985	ENOG4105BZU	Histidine kinase
EXZ61_RS13990	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
EXZ61_RS14010	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
EXZ61_RS14020	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
EXZ61_RS14035	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
EXZ61_RS14045	ENOG4107S2Z	UPF0761 membrane protein
EXZ61_RS14055	ENOG4105CQB	FAD linked oxidase domain protein
EXZ61_RS14070	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
EXZ61_RS14085	ENOG4105CGK	Exodeoxyribonuclease III
EXZ61_RS14095	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
EXZ61_RS14100	ENOG4105CUX	Signal transduction histidine kinase
EXZ61_RS14140	ENOG4105I08	Pseudouridine synthase
EXZ61_RS14145	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
EXZ61_RS14160	ENOG4105D3Q	Sugar transferase
EXZ61_RS14165	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
EXZ61_RS14170	ENOG4105C5E	polysaccharide biosynthesis protein
EXZ61_RS14190	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
EXZ61_RS14195	ENOG4105CKK	Glycosyl transferase, family 2
EXZ61_RS14200	ENOG4105PE8	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
EXZ61_RS14220	ENOG4105CKK	Glycosyl transferase, family 2
EXZ61_RS14230	ENOG4108XTA	Together with AlgI and AlgF, forms an inner membrane complex which probably interacts with the alginate polymerization- transport complex and adds acetyl groups at the O-2 and O-3 positions of polymannuronic acid. Acetylation of alginate
EXZ61_RS14235	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
EXZ61_RS14240	ENOG4105CGD	Nad-dependent epimerase dehydratase
EXZ61_RS14255	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
EXZ61_RS14280	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
EXZ61_RS14300	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
EXZ61_RS14305	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
EXZ61_RS14310	ENOG4105UYK	outer membrane protein a
EXZ61_RS14315	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
EXZ61_RS14320	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
EXZ61_RS14340	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
EXZ61_RS14345	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
EXZ61_RS14355	ENOG4105CFV	Tetratricopeptide repeat protein
EXZ61_RS14360	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
EXZ61_RS14365	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
EXZ61_RS14375	ENOG4107Z6W	Protein CrcB homolog
EXZ61_RS14380	ENOG4105C8Q	Methyl-accepting chemotaxis
EXZ61_RS14385	ENOG4107YZX	Universal stress protein
EXZ61_RS14405	ENOG4105CH5	extracellular solute-binding protein, family 7
EXZ61_RS14410	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
EXZ61_RS14420	ENOG41086K9	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
EXZ61_RS14435	ENOG4105KHC	sulfurtransferase
EXZ61_RS14450	ENOG4105RQF	LysR family Transcriptional regulator
EXZ61_RS14455	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
EXZ61_RS14460	ENOG4105BZU	Histidine kinase
EXZ61_RS14465	ENOG4105E5G	Alpha beta hydrolase fold
EXZ61_RS14470	ENOG4105C8Q	Methyl-accepting chemotaxis
EXZ61_RS14480	ENOG4108JQC	penicillin-binding protein 1A
EXZ61_RS14515	ENOG4105BZU	Histidine kinase
EXZ61_RS14525	ENOG4105C8Q	Methyl-accepting chemotaxis
EXZ61_RS14530	ENOG4105C2M	dna polymerase I
EXZ61_RS14535	ENOG4105CUV	Homoserine Kinase
EXZ61_RS14560	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
EXZ61_RS14565	ENOG4105EB3	Histidine kinase
EXZ61_RS14835	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
EXZ61_RS14900	ENOG4105D5K	Hemolysin activator protein
EXZ61_RS14915	ENOG4105CKT	filamentous hemagglutinin
EXZ61_RS14940	ENOG4105C4R	Atp-dependent dna helicase
EXZ61_RS14945	ENOG4107SJ1	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity)
EXZ61_RS14950	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
EXZ61_RS14955	ENOG4105C1J	atp-dependent rna helicase
EXZ61_RS14960	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
EXZ61_RS14965	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
EXZ61_RS14975	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
EXZ61_RS14990	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
EXZ61_RS14995	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
EXZ61_RS15000	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
EXZ61_RS15005	ENOG4105K5M	30s ribosomal protein S16
EXZ61_RS15035	ENOG4107S8C	mandelate racemase muconate lactonizing
EXZ61_RS15045	ENOG4105E89	ABC transporter
EXZ61_RS15050	ENOG4108ZXC	Two component transcriptional regulator, luxr family
EXZ61_RS15055	ENOG4107QIJ	Aconitate hydratase 2
EXZ61_RS15070	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
EXZ61_RS15075	ENOG4105FDP	GntR family transcriptional regulator
EXZ61_RS15085	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
EXZ61_RS15095	ENOG4105E33	succinate dehydrogenase
EXZ61_RS15100	ENOG41060IS	Flavinator of succinate dehydrogenase
EXZ61_RS15105	ENOG4105BZN	citrate synthase
EXZ61_RS15115	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
EXZ61_RS15125	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
EXZ61_RS15130	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
EXZ61_RS15135	ENOG4107QJH	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
EXZ61_RS15145	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
EXZ61_RS15150	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
EXZ61_RS15155	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
EXZ61_RS15160	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
EXZ61_RS15165	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
EXZ61_RS15170	ENOG4108VIA	integral membrane protein
EXZ61_RS15175	ENOG4105CRK	lysyL-tRNA synthetase
EXZ61_RS15180	ENOG4108VKG	metal-dependent hydrolase
EXZ61_RS15185	ENOG4105EYW	Ion transport protein
EXZ61_RS15190	ENOG4105VRT	cytoplasmic protein
EXZ61_RS15205	ENOG4105CEY	Amp-dependent synthetase and ligase
EXZ61_RS15220	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
EXZ61_RS15225	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
EXZ61_RS15230	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
EXZ61_RS15235	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
EXZ61_RS15240	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
EXZ61_RS15245	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
EXZ61_RS15255	ENOG4105C3F	Signal peptidase i
EXZ61_RS15260	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
EXZ61_RS15265	ENOG4105C0H	protease
EXZ61_RS15285	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
EXZ61_RS15290	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
EXZ61_RS15295	ENOG4105CHR	reductase
EXZ61_RS15300	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
EXZ61_RS15305	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
EXZ61_RS15310	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
EXZ61_RS15315	ENOG4105VGS	50s ribosomal protein l32
EXZ61_RS15320	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
EXZ61_RS15325	ENOG4108UHJ	MAF-like protein
EXZ61_RS15330	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
EXZ61_RS15335	ENOG4108E8C	) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
EXZ61_RS15355	ENOG4107QQB	Ribonuclease E
EXZ61_RS15360	ENOG4105BZU	Histidine kinase
EXZ61_RS15380	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
EXZ61_RS15385	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
EXZ61_RS15390	ENOG4108NEV	two component transcriptional regulator, LytTR family
EXZ61_RS15400	ENOG4105CH7	arginosuccinase
EXZ61_RS15405	ENOG4105BZU	Histidine kinase
EXZ61_RS15410	ENOG4105BZU	Histidine kinase
EXZ61_RS15420	ENOG4105EV4	Multidrug resistance protein mdtH
EXZ61_RS15455	ENOG4105XUA	cytochrome c
EXZ61_RS15475	ENOG4105EYW	Ion transport protein
EXZ61_RS15520	ENOG4105DU1	integral membrane protein, terc
EXZ61_RS15525	ENOG41063Z6	transcriptional regulator, lysR family
EXZ61_RS15550	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
EXZ61_RS15555	ENOG4105BZ4	penicillin-binding protein
EXZ61_RS15580	ENOG4108WFY	phasin family
EXZ61_RS15585	ENOG4105DMF	Dehydrogenase
EXZ61_RS15590	ENOG4105CD5	CoA-binding domain protein
EXZ61_RS15600	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
EXZ61_RS15605	ENOG4105CSR	polyphosphate kinase 2
EXZ61_RS15615	ENOG4105C5Q	Transcriptional regulator
EXZ61_RS15630	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
EXZ61_RS15635	ENOG4105BZU	Histidine kinase
EXZ61_RS15645	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
EXZ61_RS15655	ENOG4105D1Q	UPF0246 protein
EXZ61_RS15670	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
EXZ61_RS15675	ENOG4105E09	nadh pyrophosphatase
EXZ61_RS15680	ENOG4105C6T	cysteine synthase
EXZ61_RS15780	ENOG4108IV0	ABC, transporter
EXZ61_RS15785	ENOG4105C0Z	ABC transporter
EXZ61_RS15790	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
EXZ61_RS15795	ENOG4105C32	Amino acid ABC transporter (Permease)
EXZ61_RS15800	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
EXZ61_RS15805	ENOG4108YXU	transcriptional regulator AsnC family
EXZ61_RS15815	ENOG4105ETT	transcriptional Regulator, LysR family
EXZ61_RS15850	ENOG4108KQI	regulatory protein luxr
EXZ61_RS15880	ENOG4108UNC	
EXZ61_RS15890	ENOG4106NV8	metalloendopeptidase activity
EXZ61_RS15895	ENOG4108UNC	
EXZ61_RS15930	ENOG4108XM1	transcriptional regulator AsnC family
EXZ61_RS15935	ENOG4108428	Inherit from COG: -acetyltransferase
EXZ61_RS15945	ENOG4105D1H	recombination factor protein RarA
EXZ61_RS15950	ENOG4105VSH	4-oxalocrotonate tautomerase
EXZ61_RS15955	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
EXZ61_RS15960	ENOG4105CNU	cell division protein FtsK
EXZ61_RS15965	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
EXZ61_RS15970	ENOG4105C3M	thioredoxin reductase
EXZ61_RS15975	ENOG4105KDC	50s ribosomal protein l28
EXZ61_RS15980	ENOG4105W0E	50S ribosomal protein L33
EXZ61_RS16000	ENOG4105E0F	Histidine kinase
EXZ61_RS16005	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
EXZ61_RS16015	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
EXZ61_RS16020	ENOG4108YXG	UPF0502 protein
EXZ61_RS16025	ENOG4105CC9	acyl-Coa dehydrogenase
EXZ61_RS16030	ENOG4105X7H	acyl-CoA dehydrogenase
EXZ61_RS16045	ENOG4107Z3H	Transcriptional regulator, TetR family
EXZ61_RS16065	ENOG4105DTN	riboflavin biosynthesis protein ribF
EXZ61_RS16070	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
EXZ61_RS16075	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
EXZ61_RS16085	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
EXZ61_RS16090	ENOG4105C8Q	Methyl-accepting chemotaxis
EXZ61_RS16100	ENOG4108IPJ	Membrane
EXZ61_RS16105	ENOG4106UW1	Major Facilitator superfamily
EXZ61_RS16110	ENOG4108BRW	Activates expression of the rhaSR operon in response to L-rhamnose (By similarity)
EXZ61_RS16115	ENOG4105CHR	reductase
EXZ61_RS16120	ENOG41061DF	Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P (By similarity)
EXZ61_RS16125	ENOG4106N3A	copper homeostasis protein cutc
EXZ61_RS16130	ENOG4106UX7	integral membrane protein
EXZ61_RS16135	ENOG4105CKW	Inner membrane protein yedI
EXZ61_RS16150	ENOG4105CYC	Transferase
EXZ61_RS16180	ENOG4107TTQ	Alpha beta hydrolase fold
EXZ61_RS16220	ENOG4105CGH	5'-nucleotidase
EXZ61_RS16230	ENOG4105D3G	Pseudouridine synthase
EXZ61_RS16235	ENOG4105DB7	PHP domain protein
EXZ61_RS16240	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
EXZ61_RS16245	ENOG4108Z4T	Peptidase M50
EXZ61_RS16250	ENOG4105C31	Tryptophanyl-tRNA synthetase
EXZ61_RS16255	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
EXZ61_RS16260	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
EXZ61_RS16265	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
EXZ61_RS16275	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
EXZ61_RS16280	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EXZ61_RS16285	ENOG4105K46	50S ribosomal protein l27
EXZ61_RS16290	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
EXZ61_RS16295	ENOG4105EAH	synthase
EXZ61_RS16300	ENOG4107QHF	type ii secretion system protein e
EXZ61_RS16310	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
EXZ61_RS16315	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
EXZ61_RS16330	ENOG4105M6F	mutator MutT protein
EXZ61_RS16340	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
EXZ61_RS16345	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
EXZ61_RS16350	ENOG4105DR5	peptidase
EXZ61_RS16365	ENOG4105KB2	stringent starvation protein b
EXZ61_RS16370	ENOG4107MKT	Stringent starvation protein a
EXZ61_RS16375	ENOG4105EIX	cytochrome c1
EXZ61_RS16380	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
EXZ61_RS16385	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
EXZ61_RS16390	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
EXZ61_RS16395	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
EXZ61_RS16400	ENOG4107QNR	UPF0135 protein
EXZ61_RS16410	ENOG4105C0H	protease
EXZ61_RS16415	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
EXZ61_RS16420	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
EXZ61_RS16430	ENOG4105K59	histidine triad (HIT) protein
EXZ61_RS16435	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
EXZ61_RS16440	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
EXZ61_RS16445	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
EXZ61_RS16450	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
EXZ61_RS16455	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
EXZ61_RS16460	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
EXZ61_RS16465	ENOG4105CIH	Imidazole acetol-phosphate transaminase
EXZ61_RS16500	ENOG410642W	LysR family Transcriptional regulator
EXZ61_RS16525	ENOG4105DGI	Alkaline phosphatase
EXZ61_RS16530	ENOG4105D9P	serine threonine protein kinase
EXZ61_RS16565	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
EXZ61_RS16590	ENOG4105C2C	drug resistance transporter, Bcr CflA
EXZ61_RS16600	ENOG4108594	Permease of the drug metabolite transporter
EXZ61_RS16615	ENOG4105K4H	Nlp p60 protein
EXZ61_RS16620	ENOG4105CVE	Lytic murein transglycosylase
EXZ61_RS16625	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
EXZ61_RS16635	ENOG4108ZX6	Electron transport protein SCO1 SenC
EXZ61_RS16640	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
EXZ61_RS16665	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
EXZ61_RS16675	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
EXZ61_RS16685	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
EXZ61_RS16690	ENOG4106T9E	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
EXZ61_RS16695	ENOG41081UC	Inherit from COG: Competence protein
EXZ61_RS16700	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
EXZ61_RS16705	ENOG4105D1F	ATP-binding protein
EXZ61_RS16710	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
EXZ61_RS16725	ENOG4105CHU	acetyl-coa acetyltransferase
EXZ61_RS16735	ENOG4106RE7	Cytochrome
EXZ61_RS16780	ENOG4108Z20	Acyl-transferase
EXZ61_RS16785	ENOG4105CD3	dihydroorotase
EXZ61_RS16790	ENOG4105CXT	aspartate transcarbamylase
EXZ61_RS16795	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
EXZ61_RS16800	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
EXZ61_RS16805	ENOG4108UJU	UPF0301 protein
EXZ61_RS16820	ENOG4105C8Q	Methyl-accepting chemotaxis
EXZ61_RS16830	ENOG4105M3Z	response regulator
EXZ61_RS16835	ENOG4108UNF	response regulator
EXZ61_RS16840	ENOG4105VCQ	rubredoxin
EXZ61_RS16850	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
EXZ61_RS16870	ENOG4105VNH	ABC transporter solute-binding protein
EXZ61_RS16880	ENOG4106CJB	Phospholipase Carboxylesterase
EXZ61_RS16885	ENOG4105R8A	Heat shock protein
EXZ61_RS16890	ENOG4105CXZ	ABC transporter, permease
EXZ61_RS16900	ENOG4108VGW	abc transporter atp-binding protein
EXZ61_RS16910	ENOG4105BZU	Histidine kinase
EXZ61_RS16915	ENOG4107QZF	nitrite reductase NADPH large subunit
EXZ61_RS16925	ENOG4105VCQ	rubredoxin
EXZ61_RS16950	ENOG4105FDR	Membrane
EXZ61_RS16955	ENOG4105J0Q	Transcriptional regulator
EXZ61_RS16960	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
EXZ61_RS16965	ENOG4107QN2	dihydrolipoyl dehydrogenase
EXZ61_RS16975	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
EXZ61_RS17010	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
EXZ61_RS17040	ENOG4105C7B	Threonine dehydratase
EXZ61_RS17050	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
EXZ61_RS17055	ENOG4108Z9W	Outer membrane porin
EXZ61_RS17060	ENOG4108Z9W	Outer membrane porin
EXZ61_RS17075	ENOG4105CH2	amidohydrolase
EXZ61_RS17085	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
EXZ61_RS17090	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
EXZ61_RS17095	ENOG4107QP8	phosphohexose isomerase
EXZ61_RS17100	ENOG4105T0Z	Conserved Protein
EXZ61_RS17110	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
EXZ61_RS17120	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
EXZ61_RS17125	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
EXZ61_RS17135	ENOG4105BZU	Histidine kinase
EXZ61_RS17140	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
EXZ61_RS17145	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
EXZ61_RS17160	ENOG4105BZU	Histidine kinase
EXZ61_RS17170	ENOG4105CW0	outer membrane usher protein
EXZ61_RS17175	ENOG4105GQR	Chaperone
EXZ61_RS17240	ENOG4105NNS	Autoinducer synthesis protein
EXZ61_RS17265	ENOG4105CMG	Carbohydrate kinase
EXZ61_RS17270	ENOG4105DKD	Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity)
EXZ61_RS17305	ENOG4107RH7	Nicotinate phosphoribosyltransferase
EXZ61_RS17320	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
EXZ61_RS17325	ENOG4105E4G	Type IV pilus
EXZ61_RS17350	ENOG4108JQC	penicillin-binding protein 1A
EXZ61_RS17355	ENOG4105XQ6	frataxin-like protein
EXZ61_RS17365	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
EXZ61_RS17370	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
EXZ61_RS17375	ENOG4105CRE	cytochrome C
EXZ61_RS17380	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
EXZ61_RS17385	ENOG4106RE7	Cytochrome
EXZ61_RS17390	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
EXZ61_RS17405	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
EXZ61_RS17415	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
EXZ61_RS17435	ENOG410846T	CoA-transferase family III
EXZ61_RS17450	ENOG4105EUB	pirin domain protein
EXZ61_RS17470	ENOG410609C	Acyl carrier protein
EXZ61_RS17495	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
EXZ61_RS17505	ENOG4105BZU	Histidine kinase
EXZ61_RS17515	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
EXZ61_RS17525	ENOG4105CBN	LysR family transcriptional regulator
EXZ61_RS17535	ENOG4105BZU	Histidine kinase
EXZ61_RS17565	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EXZ61_RS17575	ENOG4105DEI	Mannitol dehydrogenase
EXZ61_RS17585	ENOG4105CMG	Carbohydrate kinase
EXZ61_RS17590	ENOG4105BZU	Histidine kinase
EXZ61_RS17620	ENOG4105QVC	MOSC domain-containing protein
EXZ61_RS17620	ENOG4105QVC	MOSC domain-containing protein
EXZ61_RS17630	ENOG4105C0B	DNA polymerase III (alpha subunit)
EXZ61_RS17635	ENOG4105DZ2	Transcriptional regulator
EXZ61_RS17640	ENOG4108TWJ	NADH dehydrogenase subunit 5
EXZ61_RS17645	ENOG4105EVH	UPF0753 protein
EXZ61_RS17650	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
EXZ61_RS17670	ENOG4105C8Q	Methyl-accepting chemotaxis
EXZ61_RS17675	ENOG4105I5W	Transporter
EXZ61_RS17685	ENOG4105D7T	ABC transporter
EXZ61_RS17690	ENOG4108IFG	nitrite reductase, (NAD(P)H)
EXZ61_RS17705	ENOG4105NSG	hemerythrin hhe cation binding domain protein
EXZ61_RS17720	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
EXZ61_RS17735	ENOG4108IGT	Dipeptidase
EXZ61_RS17750	ENOG4105DF6	Fe-S oxidoreductase
EXZ61_RS17755	ENOG4105C10	Electron transfer flavoprotein
EXZ61_RS17765	ENOG4105DVW	rieske (2Fe-2S)
EXZ61_RS17770	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
EXZ61_RS17780	ENOG4108IJ7	Glycine betaine
EXZ61_RS17785	ENOG4108HQS	Glycine betaine
EXZ61_RS17790	ENOG4105ECQ	AraC Family Transcriptional Regulator
EXZ61_RS17805	ENOG4105C26	Dehydrogenase
EXZ61_RS17810	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
EXZ61_RS17830	ENOG4105BZU	Histidine kinase
EXZ61_RS17870	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
EXZ61_RS17885	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
EXZ61_RS17890	ENOG4105E4C	Lytic transglycosylase catalytic
EXZ61_RS17900	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
EXZ61_RS17905	ENOG4105ETX	regulatoR
EXZ61_RS17915	ENOG4105BZU	Histidine kinase
EXZ61_RS18015	ENOG4108WTW	DNA transposition protein
EXZ61_RS18035	ENOG4105IKI	host-nuclease inhibitor protein
EXZ61_RS18095	ENOG4105TKZ	Tail Sheath
EXZ61_RS18130	ENOG4105WR6	Phage protein, GP46
EXZ61_RS18175	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EXZ61_RS18205	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
EXZ61_RS18215	ENOG4105EMU	Dehydrogenase
EXZ61_RS18225	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
EXZ61_RS18235	ENOG4105CVJ	phosphoglycerate mutase
EXZ61_RS18255	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
EXZ61_RS18260	ENOG4108UHE	carbonic anhydrase
EXZ61_RS18270	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
EXZ61_RS18275	ENOG4105C9A	Phoh family
EXZ61_RS18280	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
EXZ61_RS18300	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
EXZ61_RS18310	ENOG4108ZXC	Two component transcriptional regulator, luxr family
EXZ61_RS18320	ENOG4107SNB	ankyrin repeat protein YahD
EXZ61_RS18330	ENOG4105DR5	peptidase
EXZ61_RS18335	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
EXZ61_RS18340	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
EXZ61_RS18355	ENOG4108UJD	30S ribosomal protein S9
EXZ61_RS18360	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
EXZ61_RS18365	ENOG4105D6S	protein involved in catabolism of external DNA
EXZ61_RS18370	ENOG4105SYT	Methylenetetrahydrofolate reductase
EXZ61_RS18375	ENOG4105DX0	Hemolysin A
EXZ61_RS18380	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
EXZ61_RS18390	ENOG4105CG3	alpha amylase, catalytic region
EXZ61_RS18395	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
EXZ61_RS18400	ENOG4105S9S	Binding-protein-dependent transport systems, inner membrane component
EXZ61_RS18405	ENOG4105EPJ	extracellular solute-binding protein family 1
EXZ61_RS18410	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EXZ61_RS18415	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
EXZ61_RS18420	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
EXZ61_RS18430	ENOG41067B5	Histone deacetylase superfamily protein
EXZ61_RS18445	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
EXZ61_RS18460	ENOG4105DHQ	Histidine kinase
EXZ61_RS18465	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
EXZ61_RS18500	ENOG4105CSH	Transporter
EXZ61_RS18515	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
EXZ61_RS18520	ENOG4108JJB	ABC transporter
EXZ61_RS18530	ENOG4107ZYJ	bioY protein
EXZ61_RS18535	ENOG4107F3J	Amp-dependent synthetase and ligase
EXZ61_RS18550	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
EXZ61_RS18570	ENOG4107QX3	carboxylase
EXZ61_RS18585	ENOG4105K5B	UPF0225 protein
EXZ61_RS18595	ENOG4107U32	Beta-lactamase domain protein
EXZ61_RS18600	ENOG4105C1G	acyl-Coa dehydrogenase
EXZ61_RS18605	ENOG4108RU0	short-chain dehydrogenase reductase
EXZ61_RS18615	ENOG4105CHU	acetyl-coa acetyltransferase
EXZ61_RS18625	ENOG4105C2C	drug resistance transporter, Bcr CflA
EXZ61_RS18630	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
EXZ61_RS18635	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
EXZ61_RS18650	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
EXZ61_RS18655	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
EXZ61_RS18660	ENOG41077A9	carbonic anhydrase
EXZ61_RS18670	ENOG4105C1G	acyl-Coa dehydrogenase
EXZ61_RS18675	ENOG4108Z6Z	Transcriptional regulator
EXZ61_RS18705	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
EXZ61_RS18710	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
EXZ61_RS18715	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
EXZ61_RS18720	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
EXZ61_RS18725	ENOG4108JU5	Magnesium and cobalt efflux protein
EXZ61_RS18840	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
EXZ61_RS18845	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
EXZ61_RS18850	ENOG4105BZU	Histidine kinase
EXZ61_RS18855	ENOG4108V3W	Chemotaxis protein, CheW
EXZ61_RS18860	ENOG4105CBS	Chea signal transduction histidine kinase
EXZ61_RS18875	ENOG4105BZU	Histidine kinase
EXZ61_RS18880	ENOG4105WH1	Two component transcriptional regulator luxr family
EXZ61_RS18885	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
EXZ61_RS18890	ENOG4105VS8	Flagellar biosynthetic protein fliq
EXZ61_RS18895	ENOG4105CN7	Flagellar biosynthetic protein FliP
EXZ61_RS18905	ENOG4105DD5	Flagellar motor switch protein
EXZ61_RS18910	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
EXZ61_RS18930	ENOG4108JIR	Flagellum-specific ATP synthase
EXZ61_RS18940	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
EXZ61_RS18945	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
EXZ61_RS18950	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
EXZ61_RS18985	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
EXZ61_RS19035	ENOG4108JJA	ABC, transporter
EXZ61_RS19045	ENOG4105DDI	hemolysin-type calcium-binding region
EXZ61_RS19055	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
EXZ61_RS19070	ENOG4105MQ3	flagellar protein FliS
EXZ61_RS19075	ENOG4105DTS	flagellar hook-associated
EXZ61_RS19085	ENOG4105I03	Flagellin
EXZ61_RS19090	ENOG4105GEH	Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity)
EXZ61_RS19095	ENOG4106CIA	Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region
EXZ61_RS19100	ENOG4107RD7	Flagellar Motor Protein, MotA
EXZ61_RS19105	ENOG4105ER2	Ompa motb domain protein
EXZ61_RS19110	ENOG4108VYJ	response regulator receiver protein
EXZ61_RS19115	ENOG4105D00	flagellar biosynthetic protein flhB
EXZ61_RS19120	ENOG4105D7B	Flagellar biosynthesis protein flha
EXZ61_RS19125	ENOG4105FZW	flagellar biosynthesis regulator FlhF
EXZ61_RS19135	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
EXZ61_RS19150	ENOG4105CKS	Flagella basal body P-ring formation protein flgA
EXZ61_RS19155	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
EXZ61_RS19160	ENOG4108ZC9	flagellar basal-body rod protein flgc
EXZ61_RS19165	ENOG4105W00	Flagellar hook capping protein
EXZ61_RS19170	ENOG4105BZE	flagellar hook protein, FlgE
EXZ61_RS19175	ENOG4108KPB	Flagellar basal-body rod protein FlgF
EXZ61_RS19180	ENOG4105CGA	flagellar basal-body rod protein FlgG
EXZ61_RS19190	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
EXZ61_RS19195	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
EXZ61_RS19205	ENOG4105DTJ	flagellar hook-associated protein
EXZ61_RS19210	ENOG4105D58	Diguanylate phosphodiesterase
EXZ61_RS19215	ENOG4108XTA	Together with AlgI and AlgF, forms an inner membrane complex which probably interacts with the alginate polymerization- transport complex and adds acetyl groups at the O-2 and O-3 positions of polymannuronic acid. Acetylation of alginate
EXZ61_RS19230	ENOG4105BZU	Histidine kinase
EXZ61_RS19235	ENOG4105BZU	Histidine kinase
EXZ61_RS19255	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
EXZ61_RS19260	ENOG4108TGY	Glutathione S-transferase
EXZ61_RS19265	ENOG4105JAB	phenazine biosynthesis protein, phzf family
EXZ61_RS19270	ENOG4107RCH	Diaminopropionate ammonia-lyase
EXZ61_RS19275	ENOG4105BZU	Histidine kinase
EXZ61_RS19285	ENOG4105BZU	Histidine kinase
EXZ61_RS19300	ENOG4105W1Y	Transcriptional regulator
EXZ61_RS19305	ENOG4105E6M	Sulphatase-modifying factor protein
EXZ61_RS19315	ENOG4105BZU	Histidine kinase
EXZ61_RS19320	ENOG4105D4P	Coproporphyrinogen iii oxidase
EXZ61_RS19325	ENOG4105VZ9	UPF0235 protein
EXZ61_RS19350	ENOG4105C1J	atp-dependent rna helicase
EXZ61_RS19370	ENOG4105DDI	hemolysin-type calcium-binding region
EXZ61_RS19395	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
EXZ61_RS19400	ENOG4108JJA	ABC, transporter
EXZ61_RS19420	ENOG4108UKI	Enoyl-CoA hydratase
EXZ61_RS19425	ENOG4105C1G	acyl-Coa dehydrogenase
EXZ61_RS19440	ENOG4105C32	Amino acid ABC transporter (Permease)
EXZ61_RS19450	ENOG4105C0Z	ABC transporter
EXZ61_RS19455	ENOG4108IV0	ABC, transporter
EXZ61_RS19465	ENOG4105KME	endoribonuclease L-psp
EXZ61_RS19470	ENOG4105C1G	acyl-Coa dehydrogenase
EXZ61_RS19485	ENOG4105T38	integral membrane protein
EXZ61_RS19490	ENOG4107VIJ	nudix hydrolase
EXZ61_RS19540	ENOG4105CS6	Rhs element vgr protein
EXZ61_RS19555	ENOG4105CYF	SMP-30 gluconolaconase LRE domain protein
EXZ61_RS19570	ENOG4105DRS	transport system, permease
EXZ61_RS19575	ENOG4105S9S	Binding-protein-dependent transport systems, inner membrane component
EXZ61_RS19580	ENOG4105XN3	extracellular solute-binding protein family 1
EXZ61_RS19590	ENOG4108IJ9	(ABC) transporter
EXZ61_RS19595	ENOG4105C01	Dihydroxy-acid dehydratase
EXZ61_RS19600	ENOG4107EJG	GntR family transcriptional regulator
EXZ61_RS19605	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
EXZ61_RS19610	ENOG4108RTU	Aldolase
EXZ61_RS19615	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
EXZ61_RS19620	ENOG41082RQ	UPF0102 protein
EXZ61_RS19625	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
EXZ61_RS19635	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
EXZ61_RS19640	ENOG4105CZX	twitching motility protein
EXZ61_RS19645	ENOG4105CZX	twitching motility protein
EXZ61_RS19650	ENOG4105DFA	alanine racemase domain protein
EXZ61_RS19690	ENOG4105D5P	Methylmalonyl-coA mutase
EXZ61_RS19695	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
EXZ61_RS19700	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
EXZ61_RS19705	ENOG4105CH2	amidohydrolase
EXZ61_RS19730	ENOG4105D5K	Hemolysin activator protein
EXZ61_RS19735	ENOG4108J2R	molybdopterin oxidoreductase
EXZ61_RS19740	ENOG4108RYK	Nad-dependent epimerase dehydratase
EXZ61_RS19750	ENOG4106PMH	Extracellular solute-binding protein family 3
EXZ61_RS19755	ENOG4107QM5	aconitate hydratase
EXZ61_RS19760	ENOG4105BZU	Histidine kinase
EXZ61_RS19770	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
EXZ61_RS19775	ENOG4105C25	Primosomal protein n'
EXZ61_RS19785	ENOG4105CR8	Transcriptional regulator
EXZ61_RS19815	ENOG4106517	Short-chain dehydrogenase reductase Sdr
EXZ61_RS19820	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
EXZ61_RS19825	ENOG4105RK9	auxin efflux carrier
EXZ61_RS19830	ENOG4105C4R	Atp-dependent dna helicase
EXZ61_RS19835	ENOG4105HDD	phospholipase
EXZ61_RS19885	ENOG4105ES5	Histidine kinase
EXZ61_RS19895	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
EXZ61_RS19905	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
EXZ61_RS19910	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
EXZ61_RS19915	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
EXZ61_RS19920	ENOG4108VZM	50s ribosomal protein L10
EXZ61_RS19925	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
EXZ61_RS19930	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
EXZ61_RS19950	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
EXZ61_RS19975	ENOG4105DK0	Indole-3-glycerol phosphate synthase
EXZ61_RS19980	ENOG4107QYG	anthranilate phosphoribosyltransferase
EXZ61_RS19985	ENOG410829K	Lysine exporter protein (Lyse ygga)
EXZ61_RS19990	ENOG4105DDQ	anthranilate synthase
EXZ61_RS20015	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EXZ61_RS20050	ENOG4105KME	endoribonuclease L-psp
EXZ61_RS20055	ENOG4107UEK	pfkb domain protein
EXZ61_RS20060	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
EXZ61_RS20065	ENOG4105HEI	LysR family (Transcriptional regulator
EXZ61_RS20070	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
EXZ61_RS20080	ENOG4105D1F	ATP-binding protein
EXZ61_RS20085	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
EXZ61_RS20090	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
EXZ61_RS20095	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
EXZ61_RS20100	ENOG4105EHM	Aminoglycoside phosphotransferase
EXZ61_RS20105	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
EXZ61_RS20125	ENOG4105C6K	Malic enzyme
EXZ61_RS20145	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
EXZ61_RS20165	ENOG4105UYK	outer membrane protein a
EXZ61_RS20195	ENOG4105DNZ	Alpha Beta Hydrolase
EXZ61_RS20205	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
EXZ61_RS20210	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
EXZ61_RS20215	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
EXZ61_RS20220	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
EXZ61_RS20225	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
EXZ61_RS20230	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
EXZ61_RS20235	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
EXZ61_RS20240	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
EXZ61_RS20250	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
EXZ61_RS20255	ENOG4105E98	transcriptional regulator DeoR family
EXZ61_RS20260	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EXZ61_RS20265	ENOG4108IJ9	(ABC) transporter
EXZ61_RS20270	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
EXZ61_RS20275	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
EXZ61_RS20290	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
EXZ61_RS20295	ENOG4105F0I	Aminotransferase
EXZ61_RS20300	ENOG4108Z43	UPF0250 protein
EXZ61_RS20305	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
EXZ61_RS20310	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
EXZ61_RS20315	ENOG4108DQG	in Escherichia coli SbmA is involved in uptake of microcin J25
EXZ61_RS20325	ENOG4105BZU	Histidine kinase
EXZ61_RS20345	ENOG4108NNI	Beta-lactamase domain-containing protein
EXZ61_RS20350	ENOG4105SKE	transcriptional Regulator LysR family
EXZ61_RS20355	ENOG4105E5W	Transporter
EXZ61_RS20360	ENOG4105KNR	Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity)
EXZ61_RS20375	ENOG4105BZU	Histidine kinase
EXZ61_RS20385	ENOG4105C0D	helicase
EXZ61_RS20390	ENOG4105BZU	Histidine kinase
EXZ61_RS20395	ENOG4105C8Q	Methyl-accepting chemotaxis
EXZ61_RS20405	ENOG4105E0X	reductase
EXZ61_RS20430	ENOG4105BZU	Histidine kinase
EXZ61_RS20440	ENOG4105CPC	Aldo Keto reductase
EXZ61_RS20455	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
EXZ61_RS20460	ENOG41080Z8	PHOSPHOCARRIER protein
EXZ61_RS20480	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EXZ61_RS20505	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
EXZ61_RS20510	ENOG41084PQ	50s ribosomal protein l29
EXZ61_RS20515	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
EXZ61_RS20520	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
EXZ61_RS20525	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
EXZ61_RS20530	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
EXZ61_RS20535	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EXZ61_RS20540	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
EXZ61_RS20545	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
EXZ61_RS20550	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
EXZ61_RS20555	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
EXZ61_RS20560	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
EXZ61_RS20565	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
EXZ61_RS20570	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
EXZ61_RS20575	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
EXZ61_RS20580	ENOG4105DZ1	carboxypeptidase
EXZ61_RS20585	ENOG4105DHZ	alpha beta
EXZ61_RS20600	ENOG4108YXA	Membrane
EXZ61_RS20605	ENOG4105D52	delta-aminolevulinic acid dehydratase
EXZ61_RS20610	ENOG4105D7N	magnesium and cobalt transport protein CorA
EXZ61_RS20630	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
EXZ61_RS20635	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
EXZ61_RS20650	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
EXZ61_RS20665	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
EXZ61_RS20675	ENOG4105E39	Enoyl-CoA hydratase
EXZ61_RS20695	ENOG4105CJN	penicillin-binding protein
EXZ61_RS20715	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
EXZ61_RS20720	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
EXZ61_RS20725	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
EXZ61_RS20735	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
EXZ61_RS20740	ENOG4105CGK	Exodeoxyribonuclease III
EXZ61_RS20750	ENOG4105EEF	Alkane 1-monooxygenase
EXZ61_RS20755	ENOG4105ERG	peptidase m48, ste24p
EXZ61_RS20760	ENOG4108E7F	Transporter
EXZ61_RS20770	ENOG4105E0F	Histidine kinase
EXZ61_RS20775	ENOG4105XA0	heptosyltransferase ii
EXZ61_RS20785	ENOG4105CM2	brancheD-chain amino acid aminotransferase
EXZ61_RS20800	ENOG4105DHQ	Histidine kinase
EXZ61_RS20805	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
EXZ61_RS20810	ENOG4105X7T	Ni Fe-hydrogenase, b-type cytochrome subunit
EXZ61_RS20820	ENOG4105VBA	Cytochrome
EXZ61_RS20865	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
EXZ61_RS20905	ENOG4105CS6	Rhs element vgr protein
EXZ61_RS20910	ENOG4105CT7	inner membrane cred family protein
EXZ61_RS20920	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
EXZ61_RS20925	ENOG4107S74	Lysophospholipid transporter LplT
EXZ61_RS20940	ENOG4108V06	Glutathione peroxidase
EXZ61_RS20945	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
EXZ61_RS20950	ENOG4105EU8	FAD linked oxidase domain protein
EXZ61_RS20965	ENOG4105BZU	Histidine kinase
EXZ61_RS20970	ENOG4108YZA	Nitrogen regulatory protein pii
EXZ61_RS20975	ENOG4105C0P	Mg chelatase subunit ChlI
EXZ61_RS21005	ENOG4105CVR	type I restriction-modification system
EXZ61_RS21020	ENOG4105DZR	Type I site-specific deoxyribonuclease
EXZ61_RS21040	ENOG41088T4	Helicase IV
EXZ61_RS21100	ENOG4105C0P	Mg chelatase subunit ChlI
EXZ61_RS21170	ENOG4105D7Q	type ii secretion system
EXZ61_RS21175	ENOG4107QHF	type ii secretion system protein e
EXZ61_RS21180	ENOG4105C3R	Methionine synthase
EXZ61_RS21195	ENOG4105C3R	Methionine synthase
EXZ61_RS21200	ENOG4105C9U	ATP-dependent DNA helicase RecQ
EXZ61_RS21210	ENOG4105IU0	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
EXZ61_RS21215	ENOG4105C7B	Threonine dehydratase
EXZ61_RS21220	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
EXZ61_RS21250	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
EXZ61_RS21255	ENOG4105DXC	membrane
EXZ61_RS21270	ENOG4105BZU	Histidine kinase
EXZ61_RS21275	ENOG4108UYE	Lactoylglutathione lyase
EXZ61_RS21280	ENOG4105ETT	transcriptional Regulator, LysR family
EXZ61_RS21285	ENOG410829K	Lysine exporter protein (Lyse ygga)
EXZ61_RS21295	ENOG4107S76	domain protein
EXZ61_RS21345	ENOG4105E39	Enoyl-CoA hydratase
EXZ61_RS21350	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
EXZ61_RS21355	ENOG4105U3E	Transcriptional regulator
EXZ61_RS21385	ENOG4105BZU	Histidine kinase
EXZ61_RS21390	ENOG4107R6F	Alpha Beta Hydrolase Fold protein
EXZ61_RS21405	ENOG4105BZU	Histidine kinase
EXZ61_RS21415	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
EXZ61_RS21440	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
EXZ61_RS21445	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
EXZ61_RS21455	ENOG4105K6V	RNA polymerase
EXZ61_RS21485	ENOG4105DKK	Benzoate
EXZ61_RS21490	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
EXZ61_RS21495	ENOG4107YD3	Thioesterase
EXZ61_RS21500	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
EXZ61_RS21520	ENOG4105EVZ	LysR family transcriptional regulator
EXZ61_RS21525	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
EXZ61_RS21530	ENOG4105C26	Dehydrogenase
EXZ61_RS21535	ENOG4107R7Y	intracellular protease Pfpi family
EXZ61_RS21550	ENOG4108YAB	Invasion protein
EXZ61_RS21560	ENOG4108V7D	UPF0397 protein
EXZ61_RS21570	ENOG4105DWY	Agmatine deiminase
EXZ61_RS21585	ENOG4105DWY	Agmatine deiminase
EXZ61_RS21590	ENOG4105DCF	alanine dehydrogenase
EXZ61_RS21595	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
EXZ61_RS21605	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
EXZ61_RS21610	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
EXZ61_RS21615	ENOG4105DWV	Homoserine O-trans-acetylase
EXZ61_RS21625	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
EXZ61_RS21640	ENOG4105EXG	Transcriptional regulator
EXZ61_RS21680	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
EXZ61_RS21700	ENOG4105BZU	Histidine kinase
EXZ61_RS21740	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
EXZ61_RS21745	ENOG4105BZU	Histidine kinase
EXZ61_RS21770	ENOG4105VFU	Rna-binding protein
EXZ61_RS21775	ENOG4105EMU	Dehydrogenase
EXZ61_RS21785	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
EXZ61_RS21790	ENOG4105C2X	Arabinose 5-phosphate isomerase
EXZ61_RS21800	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
EXZ61_RS21810	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
EXZ61_RS21815	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EXZ61_RS21820	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
EXZ61_RS21825	ENOG4105X5M	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
EXZ61_RS21830	ENOG4105VG0	50S ribosomal protein l34
EXZ61_RS21905	ENOG4105C8Q	Methyl-accepting chemotaxis