locus-tag	class	description
EF513_RS00045	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EF513_RS00055	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EF513_RS00065	COG2867	negative regulation of translational initiation
EF513_RS00070	COG0488	(ABC) transporter
EF513_RS00080	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EF513_RS00095	COG0006	proline dipeptidase activity
EF513_RS00100	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EF513_RS00135	COG0142	geranyltranstransferase activity
EF513_RS00165	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EF513_RS00170	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EF513_RS00175	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EF513_RS00180	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EF513_RS00195	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EF513_RS00200	COG1396	sequence-specific DNA binding
EF513_RS00225	COG1137	ATPase activity
EF513_RS00240	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EF513_RS00240	COG0517	IMP dehydrogenase activity
EF513_RS00265	COG0307	riboflavin synthase, alpha
EF513_RS00275	COG0113	porphobilinogen synthase activity
EF513_RS00280	COG1999	signal sequence binding
EF513_RS00285	COG0745	RESPONSE REGULATOR receiver
EF513_RS00290	COG2205	protein histidine kinase activity
EF513_RS00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EF513_RS00345	COG1132	(ABC) transporter
EF513_RS00350	COG0312	modulator of DNA gyrase
EF513_RS00360	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EF513_RS00365	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EF513_RS00385	COG0463	Glycosyl transferase, family 2
EF513_RS00395	COG1196	nuclear chromosome segregation
EF513_RS00395	COG3264	Mechanosensitive ion channel
EF513_RS00405	COG1294	oxidase, subunit
EF513_RS00410	COG1271	oxidase subunit
EF513_RS00415	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EF513_RS00420	COG0450	alkyl hydroperoxide reductase
EF513_RS00435	COG4942	peptidase
EF513_RS00450	COG1573	uracil-dna glycosylase
EF513_RS00455	COG0372	Belongs to the citrate synthase family
EF513_RS00480	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EF513_RS00485	COG1324	tolerance protein
EF513_RS00510	COG1742	UPF0060 membrane protein
EF513_RS00525	COG1573	uracil-dna glycosylase
EF513_RS00540	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EF513_RS00565	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EF513_RS00570	COG0795	lipopolysaccharide-transporting ATPase activity
EF513_RS00575	COG1214	PFAM Peptidase M22, glycoprotease
EF513_RS00585	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EF513_RS00600	COG0740	serine-type endopeptidase activity
EF513_RS00605	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EF513_RS00610	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EF513_RS00615	COG0776	regulation of translation
EF513_RS00650	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EF513_RS00655	COG0528	UMP kinase activity
EF513_RS00665	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EF513_RS00680	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EF513_RS00685	COG0602	queuosine metabolic process
EF513_RS00705	COG2967	ApaG domain
EF513_RS00710	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EF513_RS00715	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EF513_RS00725	COG3202	ADP transmembrane transporter activity
EF513_RS00730	COG0720	synthase
EF513_RS00735	COG3202	ADP transmembrane transporter activity
EF513_RS00740	COG2211	Major facilitator Superfamily
EF513_RS00745	COG4946	Tricorn protease homolog
EF513_RS00745	COG0793	Belongs to the peptidase S41A family
EF513_RS00755	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EF513_RS00775	COG1968	undecaprenyl-diphosphatase activity
EF513_RS00785	COG1570	exodeoxyribonuclease VII activity
EF513_RS00790	COG2205	protein histidine kinase activity
EF513_RS00790	COG2202	Pas domain
EF513_RS00800	COG0697	spore germination
EF513_RS00810	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EF513_RS00815	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EF513_RS00820	COG0084	hydrolase, TatD family'
EF513_RS00845	COG0573	inorganic phosphate transmembrane transporter activity
EF513_RS00850	COG0581	inorganic phosphate transmembrane transporter activity
EF513_RS00855	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EF513_RS00865	COG0745	RESPONSE REGULATOR receiver
EF513_RS00880	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EF513_RS00900	COG1028	Short-chain dehydrogenase reductase Sdr
EF513_RS00920	COG1012	belongs to the aldehyde dehydrogenase family
EF513_RS00925	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EF513_RS00930	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EF513_RS00940	COG1028	Short-chain dehydrogenase reductase Sdr
EF513_RS00950	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EF513_RS00955	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EF513_RS00965	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
EF513_RS00990	COG0540	Belongs to the ATCase OTCase family
EF513_RS00995	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EF513_RS01000	COG0284	orotidine-5'-phosphate decarboxylase activity
EF513_RS01020	COG0187	DNA topoisomerase II activity
EF513_RS01060	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EF513_RS01075	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EF513_RS01080	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EF513_RS01090	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EF513_RS01095	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EF513_RS01100	COG0492	ferredoxin-NADP+ reductase activity
EF513_RS01105	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EF513_RS01115	COG4133	protoheme IX ABC transporter activity
EF513_RS01120	COG0156	8-amino-7-oxononanoate synthase activity
EF513_RS01130	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EF513_RS01140	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EF513_RS01145	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EF513_RS01150	COG0022	dehydrogenase e1 component
EF513_RS01150	COG0508	dehydrogenase complex catalyzes the overall conversion of
EF513_RS01175	COG0772	Belongs to the SEDS family
EF513_RS01180	COG0765	amino acid transport
EF513_RS01185	COG1126	abc transporter atp-binding protein
EF513_RS01200	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EF513_RS01205	COG1131	(ABC) transporter
EF513_RS01210	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EF513_RS01235	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EF513_RS01240	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EF513_RS01245	COG3743	rRNA binding
EF513_RS01245	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EF513_RS01250	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EF513_RS01255	COG1322	Protein conserved in bacteria
EF513_RS01260	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EF513_RS01265	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EF513_RS01270	COG1185	polyribonucleotide nucleotidyltransferase activity
EF513_RS01295	COG3202	ADP transmembrane transporter activity
EF513_RS01300	COG1766	The M ring may be actively involved in energy transduction
EF513_RS01305	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EF513_RS01315	COG0784	Response regulator, receiver
EF513_RS01340	COG0671	phosphoesterase, PA-phosphatase related
EF513_RS01350	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EF513_RS01355	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EF513_RS01360	COG2945	thiolester hydrolase activity
EF513_RS01365	COG1959	2 iron, 2 sulfur cluster binding
EF513_RS01380	COG0822	iron-sulfur transferase activity
EF513_RS01385	COG0316	Belongs to the HesB IscA family
EF513_RS01390	COG0484	heat shock protein binding
EF513_RS01395	COG0443	Heat shock 70 kDa protein
EF513_RS01410	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EF513_RS01415	COG0658	competence protein
EF513_RS01415	COG2333	competence protein COMEC
EF513_RS01450	COG0126	phosphoglycerate kinase activity
EF513_RS01460	COG0543	2 iron, 2 sulfur cluster binding
EF513_RS01460	COG0493	'glutamate synthase
EF513_RS01465	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EF513_RS01475	COG0745	RESPONSE REGULATOR receiver
EF513_RS01480	COG0285	dihydrofolate synthase activity
EF513_RS01490	COG0564	pseudouridine synthase activity
EF513_RS01495	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EF513_RS01505	COG3437	response regulator, receiver
EF513_RS01510	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EF513_RS01515	COG0552	protein localization to endoplasmic reticulum
EF513_RS01560	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EF513_RS01565	COG1674	ftsk spoiiie
EF513_RS01570	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EF513_RS01580	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EF513_RS01585	COG0717	Belongs to the dCTP deaminase family
EF513_RS01600	COG2205	protein histidine kinase activity
EF513_RS01615	COG2890	protein-(glutamine-N5) methyltransferase activity
EF513_RS01620	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EF513_RS01625	COG0124	histidyl-tRNA synthetase
EF513_RS01630	COG0531	amino acid
EF513_RS01635	COG0531	amino acid
EF513_RS01715	COG0488	(ABC) transporter
EF513_RS01720	COG5265	(ABC) transporter
EF513_RS01730	COG2204	response regulator
EF513_RS01735	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EF513_RS01740	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EF513_RS01750	COG0488	(ABC) transporter
EF513_RS01755	COG0617	tRNA 3'-terminal CCA addition
EF513_RS01760	COG0612	Peptidase, M16
EF513_RS01765	COG0174	glutamine synthetase
EF513_RS01790	COG0183	Belongs to the thiolase family
EF513_RS01795	COG1028	Short-chain dehydrogenase reductase Sdr
EF513_RS01815	COG1131	(ABC) transporter
EF513_RS01825	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EF513_RS01830	COG1684	flagellar biosynthetic protein fliR
EF513_RS01835	COG1987	bacterial-type flagellum assembly
EF513_RS01845	COG1558	bacterial-type flagellum-dependent cell motility
EF513_RS01855	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EF513_RS01865	COG0326	Molecular chaperone. Has ATPase activity
EF513_RS01890	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EF513_RS01895	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EF513_RS01920	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EF513_RS01925	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EF513_RS01930	COG0463	Glycosyl transferase, family 2
EF513_RS01930	COG1216	Glycosyl transferase, family 2
EF513_RS01960	COG0312	modulator of DNA gyrase
EF513_RS01965	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EF513_RS01970	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EF513_RS01990	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EF513_RS01995	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EF513_RS02005	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EF513_RS02030	COG0489	protein tyrosine kinase activity
EF513_RS02035	COG0670	Belongs to the BI1 family
EF513_RS02045	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EF513_RS02050	COG4770	biotin carboxylase activity
EF513_RS02055	COG0302	gtp cyclohydrolase
EF513_RS02070	COG1074	ATP-dependent DNA helicase activity
EF513_RS02075	COG0268	Binds directly to 16S ribosomal RNA
EF513_RS02080	COG0697	spore germination
EF513_RS02090	COG0569	domain protein
EF513_RS02095	COG2204	response regulator
EF513_RS02105	COG0179	Fumarylacetoacetate (FAA) hydrolase
EF513_RS02110	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EF513_RS02115	COG0316	Belongs to the HesB IscA family
EF513_RS02120	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EF513_RS02125	COG0018	arginyl-trna synthetase
EF513_RS02135	COG1472	Belongs to the glycosyl hydrolase 3 family
EF513_RS02145	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EF513_RS02155	COG0477	Major facilitator Superfamily
EF513_RS02160	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EF513_RS02185	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EF513_RS02190	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EF513_RS02195	COG1360	Flagellar Motor Protein
EF513_RS02200	COG1183	phosphatidylcholine synthase activity
EF513_RS02205	COG0688	phosphatidylethanolamine metabolic process
EF513_RS02210	COG1301	dicarboxylic acid transport
EF513_RS02220	COG0101	tRNA pseudouridine synthase activity
EF513_RS02240	COG1686	Belongs to the peptidase S11 family
EF513_RS02245	COG2205	protein histidine kinase activity
EF513_RS02250	COG0802	atpase or kinase
EF513_RS02270	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EF513_RS02275	COG0805	protein transport
EF513_RS02305	COG1338	Plays a role in the flagellum-specific transport system
EF513_RS02310	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EF513_RS02335	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EF513_RS02345	COG0574	Belongs to the PEP-utilizing enzyme family
EF513_RS02345	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EF513_RS02350	COG0751	glycine-tRNA ligase activity
EF513_RS02355	COG0752	glycyl-tRNA synthetase alpha subunit
EF513_RS02365	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EF513_RS02370	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EF513_RS02375	COG1136	(ABC) transporter
EF513_RS02385	COG0442	prolyl-tRNA aminoacylation
EF513_RS02390	COG1872	DUF167
EF513_RS02395	COG0180	Tryptophanyl-tRNA synthetase
EF513_RS02405	COG0024	Methionine aminopeptidase
EF513_RS02410	COG2003	Belongs to the UPF0758 family
EF513_RS02425	COG0861	Integral membrane protein TerC family
EF513_RS02440	COG1459	type II secretion system
EF513_RS02445	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EF513_RS02450	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EF513_RS02450	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EF513_RS02455	COG2902	Dehydrogenase
EF513_RS02465	COG0756	dUTP diphosphatase activity
EF513_RS02475	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EF513_RS02495	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EF513_RS02500	COG1132	(ABC) transporter
EF513_RS02520	COG0328	RNA-DNA hybrid ribonuclease activity
EF513_RS02545	COG0811	peptide transport
EF513_RS02550	COG0848	biopolymer transport protein
EF513_RS02565	COG2885	chlorophyll binding
EF513_RS02575	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EF513_RS02580	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EF513_RS02585	COG0037	tRNA processing
EF513_RS02605	COG0166	Belongs to the GPI family
EF513_RS02610	COG1758	RNA polymerase activity
EF513_RS02630	COG0564	pseudouridine synthase activity
EF513_RS02635	COG0556	nucleotide-excision repair
EF513_RS02660	COG1494	fructose-1,6-bisphosphatase
EF513_RS02670	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EF513_RS02685	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EF513_RS02705	COG0215	cysteine-tRNA ligase activity
EF513_RS02710	COG0359	binds to the 23S rRNA
EF513_RS02725	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EF513_RS02730	COG0504	CTP synthase activity
EF513_RS02735	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EF513_RS02740	COG0149	triose-phosphate isomerase activity
EF513_RS02765	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EF513_RS02775	COG1218	3'(2'),5'-bisphosphate nucleotidase
EF513_RS02790	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EF513_RS02810	COG1028	Short-chain dehydrogenase reductase Sdr
EF513_RS02830	COG0484	heat shock protein binding
EF513_RS02845	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EF513_RS02850	COG0629	single-stranded DNA binding
EF513_RS02855	COG1301	dicarboxylic acid transport
EF513_RS02865	COG1519	Transferase
EF513_RS02870	COG1663	tetraacyldisaccharide 4'-kinase activity
EF513_RS02875	COG0438	transferase activity, transferring glycosyl groups
EF513_RS02895	COG0354	folic acid binding
EF513_RS02905	COG0300	oxidoreductase activity
EF513_RS02915	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EF513_RS02920	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EF513_RS02945	COG3022	response to hydroperoxide
EF513_RS02960	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EF513_RS02970	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EF513_RS02995	COG0606	chelatase, subunit chli
EF513_RS03000	COG0012	GTP binding
EF513_RS03005	COG5508	conserved small protein
EF513_RS03025	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EF513_RS03030	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EF513_RS03045	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EF513_RS03170	COG4695	Portal protein
EF513_RS03190	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EF513_RS03200	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EF513_RS03205	COG0697	spore germination
EF513_RS03225	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EF513_RS03230	COG0542	response to heat
EF513_RS03245	COG1295	ribonuclease BN
EF513_RS03250	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EF513_RS03255	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EF513_RS03310	COG0477	Major facilitator Superfamily
EF513_RS03320	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EF513_RS03325	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EF513_RS03335	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EF513_RS03360	COG1024	Enoyl-CoA hydratase
EF513_RS03360	COG1250	3-hydroxyacyl-CoA dehydrogenase
EF513_RS03380	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EF513_RS03395	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EF513_RS03410	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EF513_RS03415	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EF513_RS03420	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EF513_RS03430	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EF513_RS03435	COG1981	membrane
EF513_RS03440	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EF513_RS03445	COG0039	L-malate dehydrogenase activity
EF513_RS03455	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EF513_RS03460	COG0567	Dehydrogenase, E1 component
EF513_RS03465	COG0508	dehydrogenase complex catalyzes the overall conversion of
EF513_RS03470	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EF513_RS03490	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EF513_RS03495	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EF513_RS03500	COG4974	Belongs to the 'phage' integrase family
EF513_RS03535	COG0659	secondary active sulfate transmembrane transporter activity
EF513_RS03540	COG2917	probably involved in intracellular septation
EF513_RS03545	COG0009	L-threonylcarbamoyladenylate synthase
EF513_RS03550	COG1192	Involved in chromosome partitioning
EF513_RS03560	COG0357	Ribosomal RNA small subunit methyltransferase G
EF513_RS03570	COG1475	DNA binding
EF513_RS03580	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EF513_RS03585	COG2094	Belongs to the DNA glycosylase MPG family
EF513_RS03600	COG4633	Protein conserved in bacteria
EF513_RS03620	COG0358	DNA primase activity
EF513_RS03625	COG0525	valine-tRNA ligase activity
EF513_RS03640	COG0330	HflC and HflK could
EF513_RS03645	COG0330	HflC and HflK could
EF513_RS03650	COG1160	GTP binding
EF513_RS03675	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EF513_RS03695	COG0708	Exodeoxyribonuclease III
EF513_RS03705	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EF513_RS03715	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EF513_RS03720	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
EF513_RS03725	COG4786	Flagellar basal body rod
EF513_RS03730	COG4786	Flagellar basal body rod
EF513_RS03750	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EF513_RS03755	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EF513_RS03790	COG0776	regulation of translation
EF513_RS03795	COG2267	carboxylic ester hydrolase activity
EF513_RS03805	COG0463	Glycosyl transferase, family 2
EF513_RS03820	COG0488	(ABC) transporter
EF513_RS03835	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EF513_RS03840	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EF513_RS03845	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EF513_RS03850	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EF513_RS03860	COG0237	dephospho-CoA kinase activity
EF513_RS03865	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EF513_RS03885	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
EF513_RS03890	COG2264	protein methyltransferase activity
EF513_RS03910	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EF513_RS03925	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EF513_RS03935	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EF513_RS03940	COG1132	(ABC) transporter
EF513_RS03945	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EF513_RS03955	COG0741	lytic transglycosylase activity
EF513_RS03960	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EF513_RS03975	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EF513_RS04000	COG0728	peptidoglycan biosynthetic process
EF513_RS04005	COG0443	Heat shock 70 kDa protein
EF513_RS04015	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EF513_RS04020	COG0022	dehydrogenase e1 component
EF513_RS04025	COG1215	transferase activity, transferring glycosyl groups
EF513_RS04040	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EF513_RS04045	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EF513_RS04060	COG0217	transcriptional regulatory protein
EF513_RS04065	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EF513_RS04070	COG0594	ribonuclease P activity
EF513_RS04080	COG0706	membrane insertase activity
EF513_RS04085	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EF513_RS04090	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EF513_RS04095	COG0194	GDP metabolic process
EF513_RS04100	COG3307	-O-antigen
EF513_RS04135	COG0193	aminoacyl-tRNA hydrolase activity
EF513_RS04140	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EF513_RS04145	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EF513_RS04160	COG0356	it plays a direct role in the translocation of protons across the membrane
EF513_RS04165	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EF513_RS04170	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EF513_RS04175	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EF513_RS04180	COG1215	transferase activity, transferring glycosyl groups
EF513_RS04185	COG1193	negative regulation of DNA recombination
EF513_RS04190	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EF513_RS04195	COG0842	Transport permease protein
EF513_RS04205	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EF513_RS04210	COG2226	methyltransferase
EF513_RS04215	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EF513_RS04220	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EF513_RS04230	COG1722	exodeoxyribonuclease VII activity
EF513_RS04270	COG0538	isocitrate dehydrogenase activity
EF513_RS04280	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EF513_RS04310	COG0415	Belongs to the DNA photolyase family
EF513_RS04315	COG0750	zinc metalloprotease
EF513_RS04330	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EF513_RS04335	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EF513_RS04340	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EF513_RS04345	COG3494	Protein of unknown function (DUF1009)
EF513_RS04370	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EF513_RS04405	COG0651	ATP synthesis coupled electron transport
EF513_RS04410	COG2111	Na H antiporter
EF513_RS04410	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EF513_RS04420	COG3474	cytochrome
EF513_RS04445	COG0105	UTP biosynthetic process
EF513_RS04465	COG3704	protein secretion by the type IV secretion system
EF513_RS04465	COG0419	ATPase involved in DNA repair
EF513_RS04470	COG3704	protein secretion by the type IV secretion system
EF513_RS04475	COG3704	protein secretion by the type IV secretion system
EF513_RS04480	COG3704	protein secretion by the type IV secretion system
EF513_RS04485	COG3451	type IV secretory pathway VirB4
EF513_RS04495	COG1845	cytochrome c oxidase, subunit III
EF513_RS04500	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
EF513_RS04505	COG0109	protoheme IX farnesyltransferase activity
EF513_RS04535	COG0698	ribose 5-phosphate isomerase
EF513_RS04585	COG0776	regulation of translation
EF513_RS04590	COG0616	signal peptide processing
EF513_RS04595	COG0539	negative regulation of cytoplasmic translation
EF513_RS04600	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EF513_RS04615	COG4536	flavin adenine dinucleotide binding
EF513_RS04620	COG0632	four-way junction helicase activity
EF513_RS04625	COG2255	four-way junction helicase activity
EF513_RS04635	COG0739	heme binding
EF513_RS04640	COG1177	transmembrane transport
EF513_RS04645	COG1176	ABC-type spermidine putrescine transport system, permease component I
EF513_RS04650	COG3842	ATPase activity
EF513_RS04655	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EF513_RS04660	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EF513_RS04670	COG2239	Acts as a magnesium transporter
EF513_RS04680	COG0321	lipoyl(octanoyl) transferase activity
EF513_RS04715	COG0792	nuclease activity
EF513_RS04720	COG0473	3-isopropylmalate dehydrogenase activity
EF513_RS04735	COG0860	N-Acetylmuramoyl-L-alanine amidase
EF513_RS04740	COG1530	ribonuclease E activity
EF513_RS04745	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EF513_RS04750	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EF513_RS04755	COG0049	tRNA binding
EF513_RS04770	COG0051	transcription antitermination factor activity, RNA binding
EF513_RS04780	COG0088	Forms part of the polypeptide exit tunnel
EF513_RS04790	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EF513_RS04795	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EF513_RS04800	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EF513_RS04805	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EF513_RS04810	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EF513_RS04815	COG0255	Belongs to the universal ribosomal protein uL29 family
EF513_RS04820	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EF513_RS04825	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EF513_RS04835	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EF513_RS04840	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EF513_RS04845	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EF513_RS04850	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EF513_RS04855	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EF513_RS04860	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EF513_RS04865	COG1841	ribosomal large subunit assembly
EF513_RS04870	COG0200	Binds to the 23S rRNA
EF513_RS04875	COG0201	protein transport
EF513_RS04880	COG0563	adenylate kinase activity
EF513_RS04885	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EF513_RS04895	COG0202	RNA polymerase activity
EF513_RS04900	COG0203	ribosomal protein L17
EF513_RS04940	COG0386	Belongs to the glutathione peroxidase family
EF513_RS04950	COG2202	Pas domain
EF513_RS04950	COG2205	protein histidine kinase activity
EF513_RS04955	COG0582	viral genome integration into host DNA
EF513_RS05010	COG0582	viral genome integration into host DNA
EF513_RS05020	COG0242	peptide deformylase activity
EF513_RS05065	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EF513_RS05070	COG0653	protein targeting
EF513_RS05080	COG0305	Participates in initiation and elongation during chromosome replication
EF513_RS05085	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EF513_RS05090	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EF513_RS05095	COG1127	ABC transporter
EF513_RS05120	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EF513_RS05125	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EF513_RS05135	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EF513_RS05205	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EF513_RS05210	COG0081	regulation of translation
EF513_RS05215	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EF513_RS05220	COG0222	ribosome binding
EF513_RS05225	COG0085	RNA polymerase activity
EF513_RS05230	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EF513_RS05260	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EF513_RS05265	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EF513_RS05275	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EF513_RS05290	COG0779	Required for maturation of 30S ribosomal subunits
EF513_RS05300	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EF513_RS05305	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EF513_RS05310	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EF513_RS05315	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EF513_RS05325	COG0142	geranyltranstransferase activity
EF513_RS05330	COG0204	Acyl-transferase
EF513_RS05340	COG2887	Belongs to the helicase family. UvrD subfamily
EF513_RS05350	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EF513_RS05355	COG0336	Belongs to the RNA methyltransferase TrmD family
EF513_RS05360	COG0335	large ribosomal subunit rRNA binding
EF513_RS05365	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EF513_RS05370	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EF513_RS05405	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EF513_RS05410	COG0527	aspartate kinase activity
EF513_RS05415	COG0281	malic enzyme
EF513_RS05415	COG0280	phosphate acetyltransferase
EF513_RS05420	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EF513_RS05465	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EF513_RS05470	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EF513_RS05470	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EF513_RS05475	COG1007	ATP synthesis coupled electron transport
EF513_RS05480	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EF513_RS05485	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EF513_RS05490	COG0713	ATP synthesis coupled electron transport
EF513_RS05505	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EF513_RS05515	COG1034	ATP synthesis coupled electron transport
EF513_RS05525	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EF513_RS05530	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EF513_RS05535	COG0649	NAD binding
EF513_RS05540	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EF513_RS05550	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EF513_RS05565	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
EF513_RS05575	COG0861	Integral membrane protein TerC family
EF513_RS05585	COG0196	riboflavin kinase activity
EF513_RS05600	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EF513_RS05605	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EF513_RS05615	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
EF513_RS05630	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EF513_RS05660	COG4120	Belongs to the binding-protein-dependent transport system permease family
EF513_RS05665	COG3842	ATPase activity
EF513_RS05685	COG0758	DNA mediated transformation
EF513_RS05690	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EF513_RS05720	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EF513_RS05725	COG0322	excinuclease ABC activity
EF513_RS05730	COG2271	Major facilitator Superfamily
EF513_RS05755	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
EF513_RS05760	COG1138	Cytochrome C-type biogenesis protein
EF513_RS05775	COG3088	subunit of a heme lyase
EF513_RS05790	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EF513_RS05800	COG0189	ligase activity
EF513_RS05810	COG0495	leucyl-tRNA aminoacylation
EF513_RS05850	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EF513_RS05855	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EF513_RS05865	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EF513_RS05870	COG1309	transcriptional regulator
EF513_RS05885	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EF513_RS05890	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EF513_RS05895	COG0156	8-amino-7-oxononanoate synthase activity
EF513_RS05900	COG0596	Alpha beta hydrolase
EF513_RS05905	COG2226	methyltransferase
EF513_RS05910	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EF513_RS05930	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EF513_RS06025	COG2801	Transposase and inactivated derivatives
EF513_RS06130	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EF513_RS06145	COG1132	(ABC) transporter
EF513_RS06170	COG0477	Major facilitator Superfamily
EF513_RS06205	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EF513_RS06210	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EF513_RS06220	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EF513_RS06225	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EF513_RS06240	COG2155	Conserved Protein
EF513_RS06245	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EF513_RS06250	COG0242	peptide deformylase activity
EF513_RS06260	COG3451	type IV secretory pathway VirB4
EF513_RS06280	COG0416	fatty acid biosynthetic process
EF513_RS06285	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EF513_RS06295	COG5002	protein histidine kinase activity
EF513_RS06305	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EF513_RS06310	COG0508	dehydrogenase complex catalyzes the overall conversion of
EF513_RS06315	COG1114	Component of the transport system for branched-chain amino acids
EF513_RS06365	COG0513	Belongs to the DEAD box helicase family
EF513_RS06380	COG2205	protein histidine kinase activity
EF513_RS06380	COG2198	Histidine kinase
EF513_RS06380	COG0784	Response regulator, receiver
EF513_RS06380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EF513_RS06395	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EF513_RS06400	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EF513_RS06400	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EF513_RS06430	COG2610	gluconate transmembrane transporter activity
EF513_RS06450	COG0483	inositol monophosphate 1-phosphatase activity
EF513_RS06465	COG1830	Aldolase
EF513_RS06470	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EF513_RS06490	COG0793	Belongs to the peptidase S41A family
EF513_RS06495	COG0628	permease
EF513_RS06530	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
EF513_RS06540	COG4106	trans-aconitate 2-methyltransferase activity
EF513_RS06550	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EF513_RS06560	COG2070	2-Nitropropane dioxygenase
EF513_RS06570	COG0739	heme binding
EF513_RS06580	COG0436	Aminotransferase
EF513_RS06585	COG2119	membrane
EF513_RS06590	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EF513_RS06590	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EF513_RS06595	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EF513_RS06595	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EF513_RS06605	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EF513_RS06605	COG0512	Glutamine amidotransferase of anthranilate synthase
EF513_RS06615	COG0537	adenosine 5'-monophosphoramidase activity
EF513_RS06620	COG0736	holo-[acyl-carrier-protein] synthase activity
EF513_RS06630	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EF513_RS06655	COG0482	sulfurtransferase activity
EF513_RS06665	COG1028	Short-chain dehydrogenase reductase Sdr
EF513_RS06685	COG1040	competence protein
EF513_RS06695	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EF513_RS06700	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EF513_RS06705	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EF513_RS06725	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EF513_RS06750	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EF513_RS06760	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EF513_RS06800	COG1749	Flagellar hook protein flgE
EF513_RS06835	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EF513_RS06855	COG4251	negative regulation of phosphorylation
EF513_RS06885	COG1770	oligopeptidase
EF513_RS06890	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EF513_RS06895	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EF513_RS06900	COG0574	Belongs to the PEP-utilizing enzyme family
EF513_RS06900	COG3848	Pyruvate phosphate dikinase
EF513_RS06905	COG0529	Catalyzes the synthesis of activated sulfate
EF513_RS06920	COG1881	PFAM PEBP family protein
EF513_RS06930	COG0783	Belongs to the Dps family
EF513_RS06960	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EF513_RS06980	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EF513_RS06985	COG1187	pseudouridine synthase activity
EF513_RS06990	COG0742	ribosomal rna small subunit methyltransferase
EF513_RS06995	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EF513_RS07005	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EF513_RS07015	COG0505	Belongs to the CarA family
EF513_RS07035	COG0590	tRNA wobble adenosine to inosine editing
EF513_RS07050	COG0167	dihydroorotate dehydrogenase activity
EF513_RS07060	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EF513_RS07070	COG1278	Cold shock
EF513_RS07075	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EF513_RS07075	COG0456	acetyltransferase
EF513_RS07105	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EF513_RS07110	COG1686	Belongs to the peptidase S11 family
EF513_RS07115	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EF513_RS07125	COG3038	cytochrome b561
EF513_RS07145	COG1217	gtp-binding protein TYPA
EF513_RS07180	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EF513_RS07245	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EF513_RS07255	COG1132	(ABC) transporter
EF513_RS07290	COG1673	EVE domain
EF513_RS07325	COG0653	protein targeting
EF513_RS07365	COG0140	phosphoribosyl-ATP diphosphatase activity
EF513_RS07380	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EF513_RS07400	COG3186	Phenylalanine-4-hydroxylase
EF513_RS07420	COG3844	kynureninase activity
EF513_RS07455	COG0666	response to abiotic stimulus
EF513_RS07535	COG1051	belongs to the nudix hydrolase family
EF513_RS07590	COG0463	Glycosyl transferase, family 2
EF513_RS07605	COG1752	Esterase of the alpha-beta hydrolase superfamily
EF513_RS07610	COG2081	HI0933 family
EF513_RS07620	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
EF513_RS07640	COG3750	Belongs to the UPF0335 family
EF513_RS07645	COG2835	tetraacyldisaccharide 4'-kinase activity
EF513_RS07715	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EF513_RS07720	COG1054	Belongs to the UPF0176 family
EF513_RS07770	COG0799	negative regulation of ribosome biogenesis
EF513_RS07775	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EF513_RS07785	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EF513_RS07790	COG0681	Belongs to the peptidase S26 family
EF513_RS07795	COG0571	ribonuclease III activity
EF513_RS07810	COG3736	Type IV secretory pathway, component VirB8
EF513_RS07820	COG2948	multi-organism process
EF513_RS07825	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
EF513_RS07840	COG0471	metal ion transport