locus-tag	class	description
IHV77_RS00005	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
IHV77_RS00010	COG2166	iron-sulfur cluster assembly
IHV77_RS00015	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IHV77_RS00020	COG1525	nuclease
IHV77_RS00030	COG1346	cytolysis
IHV77_RS00040	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IHV77_RS00045	COG0142	geranyltranstransferase activity
IHV77_RS00070	COG0315	cyclic pyranopterin monophosphate synthase activity
IHV77_RS00075	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IHV77_RS00080	COG0314	molybdopterin synthase activity
IHV77_RS00085	COG1528	Iron-storage protein
IHV77_RS00090	COG1528	Iron-storage protein
IHV77_RS00165	COG2925	Exonuclease
IHV77_RS00170	COG0697	spore germination
IHV77_RS00180	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
IHV77_RS00195	COG2920	part of a sulfur-relay system
IHV77_RS00200	COG0704	Plays a role in the regulation of phosphate uptake
IHV77_RS00210	COG0745	RESPONSE REGULATOR receiver
IHV77_RS00215	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IHV77_RS00220	COG0581	inorganic phosphate transmembrane transporter activity
IHV77_RS00225	COG0573	inorganic phosphate transmembrane transporter activity
IHV77_RS00240	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IHV77_RS00245	COG0589	response to stress
IHV77_RS00250	COG5266	PFAM Nickel transport complex, NikM subunit, transmembrane
IHV77_RS00255	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IHV77_RS00260	COG0583	DNA-binding transcription factor activity
IHV77_RS00265	COG2840	Smr protein MutS2
IHV77_RS00270	COG2890	protein-(glutamine-N5) methyltransferase activity
IHV77_RS00275	COG0583	DNA-binding transcription factor activity
IHV77_RS00280	COG1187	pseudouridine synthase activity
IHV77_RS00285	COG0009	L-threonylcarbamoyladenylate synthase
IHV77_RS00290	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IHV77_RS00300	COG0508	dehydrogenase complex catalyzes the overall conversion of
IHV77_RS00305	COG0567	Dehydrogenase, E1 component
IHV77_RS00310	COG1555	photosystem II stabilization
IHV77_RS00325	COG1090	epimerase
IHV77_RS00330	COG0670	Belongs to the BI1 family
IHV77_RS00340	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
IHV77_RS00345	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
IHV77_RS00350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IHV77_RS00360	COG0633	Ferredoxin
IHV77_RS00370	COG1280	lysine exporter protein (LysE YggA)
IHV77_RS00375	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IHV77_RS00390	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
IHV77_RS00425	COG1051	belongs to the nudix hydrolase family
IHV77_RS00430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IHV77_RS00435	COG1136	(ABC) transporter
IHV77_RS00435	COG0577	efflux transmembrane transporter activity
IHV77_RS00440	COG1538	Outer membrane efflux protein
IHV77_RS00450	COG3099	Belongs to the UPF0263 family
IHV77_RS00455	COG2431	L-lysine efflux transmembrane transporter activity
IHV77_RS00475	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IHV77_RS00480	COG4591	ABC-type transport system involved in lipoprotein release permease component
IHV77_RS00485	COG1136	(ABC) transporter
IHV77_RS00490	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IHV77_RS00495	COG0500	methyltransferase
IHV77_RS00500	COG2830	Protein of unknown function (DUF452)
IHV77_RS00505	COG0156	8-amino-7-oxononanoate synthase activity
IHV77_RS00510	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IHV77_RS00515	COG4591	ABC-type transport system involved in lipoprotein release permease component
IHV77_RS00520	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IHV77_RS00530	COG2912	Transglutaminase-like superfamily
IHV77_RS00535	COG2890	protein-(glutamine-N5) methyltransferase activity
IHV77_RS00540	COG1714	RDD family
IHV77_RS00545	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IHV77_RS00550	COG3101	peptidyl-lysine hydroxylation
IHV77_RS00555	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IHV77_RS00570	COG0582	viral genome integration into host DNA
IHV77_RS00575	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IHV77_RS00585	COG3177	Filamentation induced by cAMP protein fic
IHV77_RS00610	COG3561	AntA/AntB antirepressor
IHV77_RS00685	COG0285	dihydrofolate synthase activity
IHV77_RS00700	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IHV77_RS00705	COG0586	Pfam SNARE associated Golgi protein
IHV77_RS00710	COG0307	riboflavin synthase, alpha
IHV77_RS00715	COG0534	Mate efflux family protein
IHV77_RS00725	COG4178	(ABC) transporter
IHV77_RS00730	COG2814	Major facilitator Superfamily
IHV77_RS00740	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IHV77_RS00745	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
IHV77_RS00755	COG1522	sequence-specific DNA binding
IHV77_RS00760	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IHV77_RS00765	COG3025	triphosphatase activity
IHV77_RS00805	COG1392	Phosphate transport regulator
IHV77_RS00810	COG0306	phosphate transporter
IHV77_RS00815	COG4991	sh3 domain protein
IHV77_RS00820	COG0617	tRNA 3'-terminal CCA addition
IHV77_RS00830	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IHV77_RS00835	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IHV77_RS00840	COG0672	)-iron permease
IHV77_RS00855	COG0577	efflux transmembrane transporter activity
IHV77_RS00865	COG0577	efflux transmembrane transporter activity
IHV77_RS00865	COG1136	(ABC) transporter
IHV77_RS00870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IHV77_RS00885	COG2951	lytic endotransglycosylase activity
IHV77_RS00890	COG1216	Glycosyl transferase, family 2
IHV77_RS00895	COG1216	Glycosyl transferase, family 2
IHV77_RS00905	COG3306	glycosyltransferase involved in LPS biosynthesis
IHV77_RS00915	COG5039	Polysaccharide pyruvyl transferase
IHV77_RS00920	COG1434	Gram-negative-bacterium-type cell wall biogenesis
IHV77_RS00925	COG3833	ABC-type maltose transport systems, permease component
IHV77_RS00935	COG2182	Extracellular solute-binding protein
IHV77_RS00940	COG3842	ATPase activity
IHV77_RS00945	COG4580	involved in the transport of maltose and maltodextrins
IHV77_RS00955	COG2909	trisaccharide binding
IHV77_RS00965	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IHV77_RS00970	COG0305	Participates in initiation and elongation during chromosome replication
IHV77_RS00975	COG2195	Cleaves the N-terminal amino acid of tripeptides
IHV77_RS00980	COG3842	ATPase activity
IHV77_RS00985	COG1176	ABC-type spermidine putrescine transport system, permease component I
IHV77_RS00990	COG1177	transmembrane transport
IHV77_RS00995	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IHV77_RS01005	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IHV77_RS01010	COG3107	peptidoglycan biosynthetic process
IHV77_RS01020	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
IHV77_RS01025	COG2823	Periplasmic or secreted lipoprotein
IHV77_RS01030	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IHV77_RS01035	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IHV77_RS01040	COG0471	metal ion transport
IHV77_RS01050	COG0303	'Molybdopterin
IHV77_RS01055	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IHV77_RS01060	COG2391	methyltransferase activity
IHV77_RS01065	COG0425	Belongs to the sulfur carrier protein TusA family
IHV77_RS01075	COG1518	maintenance of DNA repeat elements
IHV77_RS01130	COG0140	phosphoribosyl-ATP diphosphatase activity
IHV77_RS01130	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IHV77_RS01175	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IHV77_RS01195	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IHV77_RS01205	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IHV77_RS01220	COG0720	synthase
IHV77_RS01225	COG0602	queuosine metabolic process
IHV77_RS01230	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IHV77_RS01235	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IHV77_RS01250	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IHV77_RS01255	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IHV77_RS01255	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IHV77_RS01260	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IHV77_RS01265	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IHV77_RS01280	COG4795	General secretion pathway protein
IHV77_RS01285	COG2165	general secretion pathway protein
IHV77_RS01290	COG0483	inositol monophosphate 1-phosphatase activity
IHV77_RS01295	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
IHV77_RS01300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IHV77_RS01305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IHV77_RS01310	COG1120	ATPase activity
IHV77_RS01315	COG0561	phosphatase activity
IHV77_RS01325	COG1702	phosphate starvation-inducible protein PhoH
IHV77_RS01330	COG1757	Na H antiporter
IHV77_RS01340	COG0788	formyltetrahydrofolate deformylase activity
IHV77_RS01350	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IHV77_RS01355	COG2841	Protein conserved in bacteria
IHV77_RS01365	COG0024	Methionine aminopeptidase
IHV77_RS01375	COG3112	Uncharacterised protein family (UPF0231)
IHV77_RS01380	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IHV77_RS01390	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
IHV77_RS01390	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
IHV77_RS01395	COG1560	Kdo2-lipid A biosynthetic process
IHV77_RS01400	COG0187	DNA topoisomerase II activity
IHV77_RS01410	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IHV77_RS01415	COG0786	glutamate:sodium symporter activity
IHV77_RS01420	COG5413	integral membrane protein
IHV77_RS01425	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IHV77_RS01430	COG0626	cystathionine gamma-synthase activity
IHV77_RS01435	COG0450	alkyl hydroperoxide reductase
IHV77_RS01440	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IHV77_RS01455	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IHV77_RS01500	COG4227	nucleotidyltransferase activity
IHV77_RS01560	COG4453	Protein conserved in bacteria
IHV77_RS01715	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IHV77_RS01745	COG0629	single-stranded DNA binding
IHV77_RS01795	COG0305	Participates in initiation and elongation during chromosome replication
IHV77_RS01825	COG0626	cystathionine gamma-synthase activity
IHV77_RS01830	COG3118	belongs to the thioredoxin family
IHV77_RS01850	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
IHV77_RS01855	COG1178	ABC-type Fe3 transport system permease component
IHV77_RS01860	COG4143	(ABC) transporter
IHV77_RS01870	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
IHV77_RS01880	COG1704	LemA family
IHV77_RS01890	COG0247	lactate metabolic process
IHV77_RS01890	COG0277	FAD linked oxidase domain protein
IHV77_RS01895	COG2050	protein possibly involved in aromatic compounds catabolism
IHV77_RS01910	COG1609	Transcriptional regulator
IHV77_RS01915	COG3265	gluconokinase activity
IHV77_RS01920	COG2610	gluconate transmembrane transporter activity
IHV77_RS01925	COG3118	belongs to the thioredoxin family
IHV77_RS01930	COG0492	ferredoxin-NADP+ reductase activity
IHV77_RS01935	COG4988	ABC transporter
IHV77_RS01940	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IHV77_RS01950	COG0602	queuosine metabolic process
IHV77_RS01955	COG0084	hydrolase, TatD family'
IHV77_RS01960	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IHV77_RS01970	COG2814	Major facilitator Superfamily
IHV77_RS01975	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
IHV77_RS01980	COG2824	Alkylphosphonate utilization operon protein PhnA
IHV77_RS01985	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IHV77_RS01990	COG0494	nUDIX hydrolase
IHV77_RS01995	COG1643	Atp-dependent helicase
IHV77_RS02000	COG2363	Small membrane protein
IHV77_RS02010	COG0497	DNA recombination
IHV77_RS02020	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IHV77_RS02025	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IHV77_RS02025	COG1328	CTP reductase activity
IHV77_RS02040	COG1840	ABC-type Fe3 transport system, periplasmic component
IHV77_RS02060	COG2814	Major facilitator Superfamily
IHV77_RS02065	COG4608	Belongs to the ABC transporter superfamily
IHV77_RS02070	COG0444	Belongs to the ABC transporter superfamily
IHV77_RS02075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IHV77_RS02080	COG0601	transmembrane transport
IHV77_RS02085	COG0210	DNA helicase
IHV77_RS02090	COG1840	ABC-type Fe3 transport system, periplasmic component
IHV77_RS02105	COG0437	4 iron, 4 sulfur cluster binding
IHV77_RS02110	COG2864	formate dehydrogenase
IHV77_RS02115	COG3058	Necessary for formate dehydrogenase activity
IHV77_RS02120	COG0456	acetyltransferase
IHV77_RS02125	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
IHV77_RS02140	COG1881	PFAM PEBP family protein
IHV77_RS02150	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
IHV77_RS02155	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IHV77_RS02160	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
IHV77_RS02175	COG0583	DNA-binding transcription factor activity
IHV77_RS02180	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IHV77_RS02185	COG0765	amino acid transport
IHV77_RS02190	COG0765	amino acid transport
IHV77_RS02200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IHV77_RS02215	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IHV77_RS02220	COG1286	toxin biosynthetic process
IHV77_RS02225	COG3092	negative regulation of chromosome organization
IHV77_RS02230	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IHV77_RS02235	COG0280	phosphate acetyltransferase
IHV77_RS02235	COG0857	belongs to the CobB CobQ family
IHV77_RS02240	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
IHV77_RS02245	COG0318	PFAM AMP-dependent synthetase and ligase
IHV77_RS02250	COG3065	identical protein binding
IHV77_RS02255	COG1214	PFAM Peptidase M22, glycoprotease
IHV77_RS02260	COG1199	ATP-dependent helicase activity
IHV77_RS02270	COG5007	Belongs to the BolA IbaG family
IHV77_RS02275	COG3113	response to antibiotic
IHV77_RS02280	COG2854	intermembrane phospholipid transfer
IHV77_RS02285	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IHV77_RS02290	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IHV77_RS02295	COG1127	ABC transporter
IHV77_RS02300	COG0815	Transfers the fatty acyl group on membrane lipoproteins
IHV77_RS02305	COG4535	Mg2 and Co2 transporter CorC
IHV77_RS02310	COG2017	converts alpha-aldose to the beta-anomer
IHV77_RS02315	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IHV77_RS02320	COG1085	galactose-1-phosphate uridylyltransferase
IHV77_RS02325	COG1609	Transcriptional regulator
IHV77_RS02330	COG1879	ABC-type sugar transport system periplasmic component
IHV77_RS02335	COG1129	ABC transporter
IHV77_RS02340	COG4211	Belongs to the binding-protein-dependent transport system permease family
IHV77_RS02365	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IHV77_RS02370	COG1138	Cytochrome C-type biogenesis protein
IHV77_RS02375	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
IHV77_RS02380	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IHV77_RS02385	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IHV77_RS02390	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IHV77_RS02400	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IHV77_RS02415	COG2020	methyltransferase activity
IHV77_RS02420	COG2976	Protein conserved in bacteria
IHV77_RS02430	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IHV77_RS02435	COG1426	Protein conserved in bacteria
IHV77_RS02440	COG3063	Type IV pilus biogenesis stability protein PilW
IHV77_RS02450	COG1686	Belongs to the peptidase S11 family
IHV77_RS02455	COG0612	Peptidase, M16
IHV77_RS02460	COG4771	TonB-dependent receptor
IHV77_RS02465	COG4178	(ABC) transporter
IHV77_RS02470	COG2271	Major facilitator Superfamily
IHV77_RS02475	COG3851	Histidine kinase
IHV77_RS02480	COG2197	response regulator
IHV77_RS02490	COG0641	radical SAM
IHV77_RS02495	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IHV77_RS02500	COG3119	arylsulfatase activity
IHV77_RS02505	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IHV77_RS02510	COG0730	response to heat
IHV77_RS02525	COG1530	ribonuclease E activity
IHV77_RS02530	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IHV77_RS02540	COG4536	flavin adenine dinucleotide binding
IHV77_RS02545	COG4137	Cytochrome C assembly protein
IHV77_RS02550	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IHV77_RS02555	COG0706	membrane insertase activity
IHV77_RS02565	COG0594	ribonuclease P activity
IHV77_RS02585	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IHV77_RS02590	COG0592	DNA-directed DNA polymerase activity
IHV77_RS02600	COG2975	iron-sulfur cluster assembly
IHV77_RS02605	COG0633	Ferredoxin
IHV77_RS02610	COG0443	Heat shock 70 kDa protein
IHV77_RS02620	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
IHV77_RS02625	COG0316	Belongs to the HesB IscA family
IHV77_RS02630	COG0822	iron-sulfur transferase activity
IHV77_RS02640	COG1959	2 iron, 2 sulfur cluster binding
IHV77_RS02645	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
IHV77_RS02655	COG4974	Belongs to the 'phage' integrase family
IHV77_RS02665	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
IHV77_RS02770	COG4695	Portal protein
IHV77_RS02915	COG0330	HflC and HflK could
IHV77_RS02920	COG0330	HflC and HflK could
IHV77_RS02925	COG2091	lysine biosynthetic process via aminoadipic acid
IHV77_RS02930	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IHV77_RS02940	COG0460	homoserine dehydrogenase
IHV77_RS02940	COG0527	aspartate kinase activity
IHV77_RS02945	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IHV77_RS02965	COG4185	zeta toxin
IHV77_RS02980	COG2927	DNA polymerase III (CHI subunit)
IHV77_RS02985	COG0114	fumarate hydratase activity
IHV77_RS02990	COG2268	Band 7 protein
IHV77_RS03000	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IHV77_RS03005	COG3052	prosthetic group binding
IHV77_RS03010	COG2301	Belongs to the HpcH HpaI aldolase family
IHV77_RS03015	COG3051	citrate lyase alpha subunit
IHV77_RS03020	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
IHV77_RS03020	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
IHV77_RS03025	COG0471	metal ion transport
IHV77_RS03035	COG2190	(PTS) system
IHV77_RS03040	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IHV77_RS03045	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IHV77_RS03055	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IHV77_RS03070	COG0802	atpase or kinase
IHV77_RS03075	COG0860	N-Acetylmuramoyl-L-alanine amidase
IHV77_RS03075	COG1388	LysM domain
IHV77_RS03090	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
IHV77_RS03130	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IHV77_RS03150	COG2860	membrane
IHV77_RS03160	COG1172	Belongs to the binding-protein-dependent transport system permease family
IHV77_RS03165	COG1172	Belongs to the binding-protein-dependent transport system permease family
IHV77_RS03170	COG1129	ABC transporter
IHV77_RS03180	COG4977	sequence-specific DNA binding
IHV77_RS03190	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IHV77_RS03195	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IHV77_RS03220	COG0791	NLP P60 protein
IHV77_RS03225	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IHV77_RS03230	COG0508	dehydrogenase complex catalyzes the overall conversion of
IHV77_RS03235	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
IHV77_RS03245	COG5339	Protein conserved in bacteria
IHV77_RS03250	COG0443	Heat shock 70 kDa protein
IHV77_RS03260	COG0484	heat shock protein binding
IHV77_RS03270	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IHV77_RS03275	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IHV77_RS03285	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IHV77_RS03290	COG1408	metallophosphoesterase
IHV77_RS03300	COG0549	Belongs to the carbamate kinase family
IHV77_RS03305	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IHV77_RS03310	COG1760	l-serine dehydratase
IHV77_RS03315	COG0814	amino acid
IHV77_RS03325	COG1053	succinate dehydrogenase
IHV77_RS03330	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IHV77_RS03335	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
IHV77_RS03345	COG0105	UTP biosynthetic process
IHV77_RS03435	COG0174	glutamine synthetase
IHV77_RS03440	COG1217	gtp-binding protein TYPA
IHV77_RS03445	COG0436	Aminotransferase
IHV77_RS03450	COG1169	isochorismate synthase
IHV77_RS03460	COG2267	carboxylic ester hydrolase activity
IHV77_RS03465	COG0477	Major facilitator Superfamily
IHV77_RS03470	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
IHV77_RS03475	COG0848	biopolymer transport protein
IHV77_RS03480	COG0811	peptide transport
IHV77_RS03485	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IHV77_RS03505	COG3036	rescue of stalled ribosome
IHV77_RS03510	COG1393	Belongs to the ArsC family
IHV77_RS03520	COG1720	tRNA m6t6A37 methyltransferase activity
IHV77_RS03525	COG1575	Belongs to the MenA family. Type 1 subfamily
IHV77_RS03535	COG0471	metal ion transport
IHV77_RS03540	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IHV77_RS03545	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IHV77_RS03565	COG1607	acyl-coa hydrolase
IHV77_RS03570	COG2350	Protein conserved in bacteria
IHV77_RS03575	COG0741	lytic transglycosylase activity
IHV77_RS03585	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IHV77_RS03595	COG1823	symporter activity
IHV77_RS03600	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IHV77_RS03605	COG4149	molybdate abc transporter
IHV77_RS03610	COG0725	ABC transporter, periplasmic molybdate-binding protein
IHV77_RS03615	COG2005	Transcriptional regulator
IHV77_RS03620	COG3381	protein complex oligomerization
IHV77_RS03625	COG2249	NAD(P)H dehydrogenase (quinone) activity
IHV77_RS03630	COG1585	Membrane protein implicated in regulation of membrane protease activity
IHV77_RS03635	COG0330	HflC and HflK could
IHV77_RS03645	COG2932	Transcriptional regulator
IHV77_RS03650	COG1560	Kdo2-lipid A biosynthetic process
IHV77_RS03655	COG0730	response to heat
IHV77_RS03660	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
IHV77_RS03670	COG3264	Mechanosensitive ion channel
IHV77_RS03670	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
IHV77_RS03675	COG0318	PFAM AMP-dependent synthetase and ligase
IHV77_RS03680	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
IHV77_RS03685	COG0596	Alpha beta hydrolase
IHV77_RS03690	COG0716	FMN binding
IHV77_RS03695	COG0735	belongs to the Fur family
IHV77_RS03700	COG4166	transmembrane transport
IHV77_RS03705	COG2832	Protein of unknown function (DUF454)
IHV77_RS03710	COG0339	signal peptide processing
IHV77_RS03770	COG3210	domain, Protein
IHV77_RS03775	COG2831	hemolysin activation secretion protein
IHV77_RS03780	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IHV77_RS03785	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
IHV77_RS03785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IHV77_RS03795	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IHV77_RS03805	COG1444	tRNA N-acetyltransferase activity
IHV77_RS03815	COG3715	PTS system
IHV77_RS03820	COG3716	PTS system mannose fructose sorbose family IID component
IHV77_RS03830	COG0784	Response regulator, receiver
IHV77_RS03830	COG5002	protein histidine kinase activity
IHV77_RS03830	COG2198	Histidine kinase
IHV77_RS03870	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IHV77_RS03875	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IHV77_RS03880	COG1758	RNA polymerase activity
IHV77_RS03885	COG0194	GDP metabolic process
IHV77_RS03890	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IHV77_RS03895	COG1022	Amp-dependent synthetase and ligase
IHV77_RS03900	COG0058	SHG alpha-glucan phosphorylase activity
IHV77_RS03905	COG0297	glycogen (starch) synthase activity
IHV77_RS03915	COG1523	belongs to the glycosyl hydrolase 13 family
IHV77_RS03920	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IHV77_RS03935	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IHV77_RS03955	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IHV77_RS03970	COG2226	methyltransferase
IHV77_RS03975	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IHV77_RS03980	COG0363	glucosamine-6-phosphate deaminase activity
IHV77_RS03985	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IHV77_RS03990	COG1737	Transcriptional regulator
IHV77_RS04000	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
IHV77_RS04005	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IHV77_RS04010	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IHV77_RS04010	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IHV77_RS04015	COG1929	Belongs to the glycerate kinase type-1 family
IHV77_RS04020	COG2610	gluconate transmembrane transporter activity
IHV77_RS04025	COG3835	regulator
IHV77_RS04035	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
IHV77_RS04040	COG2610	gluconate transmembrane transporter activity
IHV77_RS04045	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IHV77_RS04050	COG3622	Belongs to the hyi family
IHV77_RS04055	COG0235	Class ii aldolase
IHV77_RS04060	COG3395	kinase activity
IHV77_RS04065	COG2084	Dehydrogenase
IHV77_RS04070	COG1349	DNA-binding transcription factor activity
IHV77_RS04075	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IHV77_RS04080	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IHV77_RS04085	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IHV77_RS04090	COG1381	Involved in DNA repair and RecF pathway recombination
IHV77_RS04100	COG3266	domain, Protein
IHV77_RS04100	COG3061	Opacity-associated protein A
IHV77_RS04105	COG1509	lysine 2,3-aminomutase activity
IHV77_RS04115	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IHV77_RS04135	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IHV77_RS04140	COG2003	Belongs to the UPF0758 family
IHV77_RS04160	COG3722	fumarate hydratase activity
IHV77_RS04165	COG0246	Mannitol dehydrogenase
IHV77_RS04180	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
IHV77_RS04185	COG0437	4 iron, 4 sulfur cluster binding
IHV77_RS04190	COG3301	Polysulphide reductase, NrfD
IHV77_RS04195	COG1138	Cytochrome C-type biogenesis protein
IHV77_RS04200	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IHV77_RS04205	COG4235	cytochrome complex assembly
IHV77_RS04205	COG3088	subunit of a heme lyase
IHV77_RS04210	COG2081	HI0933 family
IHV77_RS04230	COG0277	FAD linked oxidase domain protein
IHV77_RS04245	COG0121	glutamine amidotransferase
IHV77_RS04250	COG0243	molybdopterin cofactor binding
IHV77_RS04255	COG0437	4 iron, 4 sulfur cluster binding
IHV77_RS04260	COG3302	dmso reductase anchor subunit
IHV77_RS04265	COG3381	protein complex oligomerization
IHV77_RS04270	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IHV77_RS04270	COG2221	Nitrite and sulphite reductase 4Fe-4S
IHV77_RS04280	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IHV77_RS04285	COG2814	Major facilitator Superfamily
IHV77_RS04290	COG4974	Belongs to the 'phage' integrase family
IHV77_RS04310	COG3266	domain, Protein
IHV77_RS04315	COG3266	domain, Protein
IHV77_RS04320	COG4783	chaperone-mediated protein folding
IHV77_RS04325	COG3924	membrane
IHV77_RS04330	COG4145	pantothenate transmembrane transporter activity
IHV77_RS04335	COG0697	spore germination
IHV77_RS04345	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IHV77_RS04355	COG4783	chaperone-mediated protein folding
IHV77_RS04370	COG1322	Protein conserved in bacteria
IHV77_RS04380	COG1187	pseudouridine synthase activity
IHV77_RS04395	COG4942	peptidase
IHV77_RS04400	COG2861	carbohydrate metabolic process
IHV77_RS04405	COG2197	response regulator
IHV77_RS04410	COG3072	Adenylate cyclase
IHV77_RS04420	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IHV77_RS04425	COG2183	response to ionizing radiation
IHV77_RS04465	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IHV77_RS04470	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IHV77_RS04490	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IHV77_RS04495	COG0051	transcription antitermination factor activity, RNA binding
IHV77_RS04500	COG2177	Part of the ABC transporter FtsEX involved in
IHV77_RS04505	COG2884	Cell division ATP-binding protein ftsE
IHV77_RS04510	COG0552	protein localization to endoplasmic reticulum
IHV77_RS04515	COG0742	ribosomal rna small subunit methyltransferase
IHV77_RS04520	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IHV77_RS04525	COG1070	Carbohydrate kinase
IHV77_RS04530	COG2115	Belongs to the xylose isomerase family
IHV77_RS04535	COG4213	ABC transporter substrate-binding protein
IHV77_RS04540	COG1129	ABC transporter
IHV77_RS04545	COG4214	carbohydrate transport
IHV77_RS04550	COG1609	Transcriptional regulator
IHV77_RS04550	COG2207	Transcriptional regulator
IHV77_RS04555	COG1349	DNA-binding transcription factor activity
IHV77_RS04560	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IHV77_RS04570	COG0738	Major facilitator superfamily
IHV77_RS04580	COG2801	Transposase and inactivated derivatives
IHV77_RS04585	COG2801	Transposase and inactivated derivatives
IHV77_RS04590	COG2963	transposase activity
IHV77_RS04610	COG0335	large ribosomal subunit rRNA binding
IHV77_RS04615	COG2116	formate transmembrane transporter activity
IHV77_RS04620	COG1882	Formate acetyltransferase
IHV77_RS04625	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IHV77_RS04635	COG1555	photosystem II stabilization
IHV77_RS04645	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IHV77_RS04650	COG1120	ATPase activity
IHV77_RS04670	COG4974	Belongs to the 'phage' integrase family
IHV77_RS04675	COG0732	type I restriction modification DNA specificity domain
IHV77_RS04715	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IHV77_RS04715	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IHV77_RS04730	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IHV77_RS04735	COG0542	response to heat
IHV77_RS04740	COG0463	Glycosyl transferase, family 2
IHV77_RS04745	COG1519	Transferase
IHV77_RS04755	COG5645	(Lipo)protein
IHV77_RS04760	COG0210	DNA helicase
IHV77_RS04795	COG2129	metallophosphoesterase
IHV77_RS04800	COG3172	ATPase kinase involved in NAD metabolism
IHV77_RS04810	COG3306	glycosyltransferase involved in LPS biosynthesis
IHV77_RS04815	COG2963	transposase activity
IHV77_RS04820	COG2801	Transposase and inactivated derivatives
IHV77_RS04825	COG2801	Transposase and inactivated derivatives
IHV77_RS04830	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IHV77_RS04840	COG0805	protein transport
IHV77_RS04855	COG0688	phosphatidylethanolamine metabolic process
IHV77_RS04860	COG0545	Peptidyl-prolyl cis-trans isomerase
IHV77_RS04865	COG2391	methyltransferase activity
IHV77_RS04870	COG0425	Belongs to the sulfur carrier protein TusA family
IHV77_RS04885	COG2731	YhcH YjgK YiaL family protein
IHV77_RS04895	COG4785	May be involved in cell division
IHV77_RS04900	COG0513	Belongs to the DEAD box helicase family
IHV77_RS04905	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
IHV77_RS04915	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IHV77_RS04920	COG0564	pseudouridine synthase activity
IHV77_RS04925	COG1496	oxidoreductase activity
IHV77_RS04940	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IHV77_RS04945	COG0842	Transport permease protein
IHV77_RS04950	COG1131	(ABC) transporter
IHV77_RS04965	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
IHV77_RS04970	COG0628	permease
IHV77_RS04975	COG0347	Belongs to the P(II) protein family
IHV77_RS04980	COG0521	Mo-molybdopterin cofactor biosynthetic process
IHV77_RS04985	COG0471	metal ion transport
IHV77_RS04985	COG0490	domain, Protein
IHV77_RS05005	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IHV77_RS05015	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
IHV77_RS05025	COG0750	zinc metalloprotease
IHV77_RS05030	COG0575	Belongs to the CDS family
IHV77_RS05035	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IHV77_RS05055	COG2194	sulfuric ester hydrolase activity
IHV77_RS05075	COG2226	methyltransferase
IHV77_RS05080	COG0814	amino acid
IHV77_RS05085	COG4783	chaperone-mediated protein folding
IHV77_RS05090	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IHV77_RS05095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IHV77_RS05100	COG1309	transcriptional regulator
IHV77_RS05105	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IHV77_RS05110	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IHV77_RS05115	COG1862	Preprotein translocase
IHV77_RS05125	COG3945	hemerythrin HHE cation binding domain
IHV77_RS05135	COG0343	queuine tRNA-ribosyltransferase activity
IHV77_RS05140	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IHV77_RS05145	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IHV77_RS05150	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IHV77_RS05155	COG1757	Na H antiporter
IHV77_RS05160	COG2423	ornithine cyclodeaminase activity
IHV77_RS05165	COG1522	sequence-specific DNA binding
IHV77_RS05170	COG3005	denitrification pathway
IHV77_RS05175	COG3043	anaerobic respiration
IHV77_RS05180	COG0348	domain, Protein
IHV77_RS05185	COG0437	4 iron, 4 sulfur cluster binding
IHV77_RS05195	COG3062	negative regulation of establishment of protein localization
IHV77_RS05200	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IHV77_RS05205	COG3171	Protein conserved in bacteria
IHV77_RS05215	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IHV77_RS05220	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IHV77_RS05230	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IHV77_RS05240	COG1028	Short-chain dehydrogenase reductase Sdr
IHV77_RS05245	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IHV77_RS05255	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IHV77_RS05290	COG1131	(ABC) transporter
IHV77_RS05340	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IHV77_RS05420	COG0138	bifunctional purine biosynthesis protein purh
IHV77_RS05425	COG2259	Doxx family
IHV77_RS05430	COG4232	protein-disulfide reductase activity
IHV77_RS05435	COG0745	RESPONSE REGULATOR receiver
IHV77_RS05445	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IHV77_RS05450	COG0697	spore germination
IHV77_RS05455	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IHV77_RS05465	COG0142	geranyltranstransferase activity
IHV77_RS05470	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IHV77_RS05510	COG0402	S-adenosylhomocysteine deaminase activity
IHV77_RS05515	COG3083	sulfuric ester hydrolase activity
IHV77_RS05530	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IHV77_RS05535	COG0745	RESPONSE REGULATOR receiver
IHV77_RS05540	COG2205	protein histidine kinase activity
IHV77_RS05545	COG2217	Heavy metal translocating P-type atpase
IHV77_RS05550	COG2608	mercury ion transmembrane transporter activity
IHV77_RS05555	COG0789	Transcriptional regulator
IHV77_RS05575	COG4221	oxidoreductase activity
IHV77_RS05590	COG0583	DNA-binding transcription factor activity
IHV77_RS05605	COG0778	Nitroreductase
IHV77_RS05620	COG1764	response to oxidative stress
IHV77_RS05625	COG2207	Transcriptional regulator
IHV77_RS05635	COG3115	cell septum assembly
IHV77_RS05645	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IHV77_RS05655	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IHV77_RS05695	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IHV77_RS05700	COG1739	Uncharacterized protein family UPF0029
IHV77_RS05715	COG3276	selenocysteine insertion sequence binding
IHV77_RS05720	COG1921	L-seryl-tRNASec selenium transferase activity
IHV77_RS05730	COG3059	membrane
IHV77_RS05745	COG0642	Histidine kinase
IHV77_RS05765	COG0800	Aldolase
IHV77_RS05770	COG1028	Short-chain dehydrogenase reductase Sdr
IHV77_RS05775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IHV77_RS05785	COG3250	beta-galactosidase activity
IHV77_RS05790	COG2211	Major facilitator Superfamily
IHV77_RS05810	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IHV77_RS05815	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IHV77_RS05820	COG2186	Transcriptional regulator
IHV77_RS05830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IHV77_RS05830	COG1263	PTS System
IHV77_RS05830	COG2190	(PTS) system
IHV77_RS05835	COG1584	GPR1 FUN34 yaaH family protein
IHV77_RS05840	COG1012	belongs to the aldehyde dehydrogenase family
IHV77_RS05840	COG1454	alcohol dehydrogenase
IHV77_RS05855	COG0678	peroxiredoxin activity
IHV77_RS05855	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IHV77_RS05860	COG0583	DNA-binding transcription factor activity
IHV77_RS05865	COG1309	transcriptional regulator
IHV77_RS05870	COG0730	response to heat
IHV77_RS05875	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IHV77_RS05875	COG1263	PTS System
IHV77_RS05875	COG2190	(PTS) system
IHV77_RS05880	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
IHV77_RS05900	COG0500	methyltransferase
IHV77_RS05905	COG3071	HemY protein
IHV77_RS05910	COG2959	enzyme of heme biosynthesis
IHV77_RS05920	COG0181	hydroxymethylbilane synthase activity
IHV77_RS05950	COG1072	(Pantothenic acid kinase))
IHV77_RS05970	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
IHV77_RS05975	COG1490	D-aminoacyl-tRNA deacylase activity
IHV77_RS05990	COG2258	MOSC domain
IHV77_RS05995	COG0433	COG0433 Predicted ATPase
IHV77_RS06000	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
IHV77_RS06010	COG2137	regulation of response to DNA damage stimulus
IHV77_RS06020	COG0561	phosphatase activity
IHV77_RS06040	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IHV77_RS06045	COG0038	chloride channel
IHV77_RS06050	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IHV77_RS06060	COG0606	chelatase, subunit chli
IHV77_RS06070	COG1040	competence protein
IHV77_RS06075	COG4796	Type ii and iii secretion system protein
IHV77_RS06095	COG4972	Pilus assembly protein
IHV77_RS06100	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
IHV77_RS06105	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IHV77_RS06125	COG0859	PFAM glycosyl transferase family 9
IHV77_RS06135	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IHV77_RS06145	COG3956	TIGRFAM MazG family protein
IHV77_RS06190	COG3070	regulator of competence-specific genes
IHV77_RS06200	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IHV77_RS06205	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IHV77_RS06245	COG1733	regulation of RNA biosynthetic process
IHV77_RS06250	COG0702	epimerase
IHV77_RS06255	COG0445	tRNA wobble uridine modification
IHV77_RS06260	COG0716	FMN binding
IHV77_RS06270	COG1494	fructose-1,6-bisphosphatase
IHV77_RS06275	COG0187	DNA topoisomerase II activity
IHV77_RS06280	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IHV77_RS06285	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IHV77_RS06290	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IHV77_RS06295	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IHV77_RS06300	COG0470	DNA polymerase III
IHV77_RS06305	COG0084	hydrolase, TatD family'
IHV77_RS06315	COG1253	flavin adenine dinucleotide binding
IHV77_RS06325	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IHV77_RS06325	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IHV77_RS06330	COG1105	Belongs to the carbohydrate kinase PfkB family
IHV77_RS06335	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IHV77_RS06335	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IHV77_RS06335	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
IHV77_RS06345	COG1595	DNA-templated transcription, initiation
IHV77_RS06350	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
IHV77_RS06355	COG3026	antisigma factor binding
IHV77_RS06360	COG0729	surface antigen
IHV77_RS06365	COG2911	Protein conserved in bacteria
IHV77_RS06370	COG0248	Ppx GppA phosphatase
IHV77_RS06380	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IHV77_RS06385	COG0110	maltose O-acetyltransferase activity
IHV77_RS06390	COG1238	metal cluster binding
IHV77_RS06400	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IHV77_RS06410	COG1609	Transcriptional regulator
IHV77_RS06415	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IHV77_RS06420	COG1879	ABC-type sugar transport system periplasmic component
IHV77_RS06425	COG1172	Belongs to the binding-protein-dependent transport system permease family
IHV77_RS06430	COG1129	ABC transporter
IHV77_RS06435	COG1869	D-ribose catabolic process
IHV77_RS06440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IHV77_RS06475	COG0531	amino acid
IHV77_RS06480	COG1982	Orn Lys Arg decarboxylase major
IHV77_RS06495	COG3069	C4-dicarboxylate transmembrane transporter activity
IHV77_RS06500	COG1473	amidohydrolase
IHV77_RS06505	COG0737	Belongs to the 5'-nucleotidase family
IHV77_RS06510	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IHV77_RS06520	COG0501	Belongs to the peptidase M48B family
IHV77_RS06525	COG3086	response to oxidative stress
IHV77_RS06535	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IHV77_RS06540	COG3085	chromosome segregation
IHV77_RS06545	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IHV77_RS06550	COG3084	Protein conserved in bacteria
IHV77_RS06555	COG0746	molybdenum cofactor guanylyltransferase activity
IHV77_RS06560	COG0705	Rhomboid family
IHV77_RS06565	COG1349	DNA-binding transcription factor activity
IHV77_RS06570	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IHV77_RS06575	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IHV77_RS06585	COG0584	glycerophosphoryl diester phosphodiesterase
IHV77_RS06590	COG2271	Major facilitator Superfamily
IHV77_RS06595	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IHV77_RS06605	COG0247	lactate metabolic process
IHV77_RS06615	COG2211	Major facilitator Superfamily
IHV77_RS06625	COG5295	Hep Hag repeat protein
IHV77_RS06625	COG5295	Hep Hag repeat protein
IHV77_RS06650	COG0514	ATP-dependent DNA helicase (RecQ)
IHV77_RS06665	COG0019	diaminopimelate decarboxylase activity
IHV77_RS06670	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IHV77_RS06675	COG0494	nUDIX hydrolase
IHV77_RS06680	COG1297	OPT oligopeptide transporter protein
IHV77_RS06690	COG4783	chaperone-mediated protein folding
IHV77_RS06695	COG2831	hemolysin activation secretion protein
IHV77_RS06700	COG3210	domain, Protein
IHV77_RS06750	COG1218	3'(2'),5'-bisphosphate nucleotidase
IHV77_RS06755	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IHV77_RS06760	COG0363	glucosamine-6-phosphate deaminase activity
IHV77_RS06765	COG3759	membrane
IHV77_RS06790	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IHV77_RS06800	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IHV77_RS06805	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
IHV77_RS06810	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IHV77_RS06820	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IHV77_RS06830	COG1522	sequence-specific DNA binding
IHV77_RS06835	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IHV77_RS06840	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IHV77_RS06845	COG0442	prolyl-tRNA aminoacylation
IHV77_RS06850	COG0561	phosphatase activity
IHV77_RS06855	COG0235	Class ii aldolase
IHV77_RS06860	COG3623	hexulose-6-phosphate isomerase
IHV77_RS06880	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IHV77_RS06885	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
IHV77_RS06890	COG1285	pathogenesis
IHV77_RS06900	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
IHV77_RS06905	COG2853	Lipoprotein
IHV77_RS06910	COG0251	oxidation-reduction process
IHV77_RS06930	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IHV77_RS06950	COG2195	Cleaves the N-terminal amino acid of tripeptides
IHV77_RS06960	COG0587	DNA-directed DNA polymerase activity
IHV77_RS06970	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IHV77_RS06975	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IHV77_RS06975	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IHV77_RS06980	COG1215	transferase activity, transferring glycosyl groups
IHV77_RS06985	COG0569	domain protein
IHV77_RS06995	COG0859	PFAM glycosyl transferase family 9
IHV77_RS06995	COG0457	Tetratricopeptide repeat
IHV77_RS07000	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IHV77_RS07005	COG3477	response to acidic pH
IHV77_RS07020	COG1047	Peptidyl-prolyl cis-trans
IHV77_RS07030	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
IHV77_RS07035	COG0585	pseudouridine synthase activity
IHV77_RS07045	COG1238	metal cluster binding
IHV77_RS07055	COG4942	peptidase
IHV77_RS07055	COG1388	LysM domain
IHV77_RS07065	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IHV77_RS07070	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IHV77_RS07075	COG0259	pyridoxamine-phosphate oxidase activity
IHV77_RS07080	COG0747	negative chemotaxis
IHV77_RS07085	COG1763	Mo-molybdopterin cofactor biosynthetic process
IHV77_RS07095	COG2818	Glycosylase
IHV77_RS07100	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IHV77_RS07105	COG0009	L-threonylcarbamoyladenylate synthase
IHV77_RS07110	COG0551	DNA topoisomerase type I activity
IHV77_RS07115	COG0488	(ABC) transporter
IHV77_RS07125	COG2962	Rard protein
IHV77_RS07130	COG0583	DNA-binding transcription factor activity
IHV77_RS07140	COG1879	ABC-type sugar transport system periplasmic component
IHV77_RS07150	COG1172	Belongs to the binding-protein-dependent transport system permease family
IHV77_RS07155	COG1070	Carbohydrate kinase
IHV77_RS07165	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IHV77_RS07170	COG1045	serine acetyltransferase
IHV77_RS07185	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IHV77_RS07190	COG0252	asparaginase activity
IHV77_RS07195	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
IHV77_RS07205	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IHV77_RS07210	COG0129	dihydroxy-acid dehydratase activity
IHV77_RS07215	COG0028	Belongs to the TPP enzyme family
IHV77_RS07230	COG0733	neurotransmitter:sodium symporter activity
IHV77_RS07260	COG2084	Dehydrogenase
IHV77_RS07275	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IHV77_RS07280	COG2267	carboxylic ester hydrolase activity
IHV77_RS07285	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IHV77_RS07300	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IHV77_RS07305	COG1595	DNA-templated transcription, initiation
IHV77_RS07330	COG0204	Acyl-transferase
IHV77_RS07345	COG0545	Peptidyl-prolyl cis-trans isomerase
IHV77_RS07350	COG2964	Protein conserved in bacteria
IHV77_RS07355	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
IHV77_RS07360	COG2923	Belongs to the DsrF TusC family
IHV77_RS07365	COG2168	tRNA wobble position uridine thiolation
IHV77_RS07420	COG0201	protein transport
IHV77_RS07445	COG0202	RNA polymerase activity
IHV77_RS07460	COG1464	Belongs to the NlpA lipoprotein family
IHV77_RS07475	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IHV77_RS07505	COG2188	Transcriptional regulator
IHV77_RS07510	COG1640	4-alpha-glucanotransferase
IHV77_RS07515	COG0058	SHG alpha-glucan phosphorylase activity
IHV77_RS07525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IHV77_RS07525	COG1263	PTS System
IHV77_RS07525	COG2190	(PTS) system
IHV77_RS07530	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IHV77_RS07540	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IHV77_RS07550	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IHV77_RS07560	COG0456	acetyltransferase
IHV77_RS07565	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IHV77_RS07590	COG1556	Lactate utilization protein
IHV77_RS07595	COG1139	Iron-sulfur cluster binding protein
IHV77_RS07600	COG0247	lactate metabolic process
IHV77_RS07605	COG1620	l-lactate permease
IHV77_RS07610	COG2321	neutral zinc metallopeptidase
IHV77_RS07615	COG1652	LysM domain
IHV77_RS07630	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IHV77_RS07635	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IHV77_RS07640	COG0250	Participates in transcription elongation, termination and antitermination
IHV77_RS07675	COG0006	proline dipeptidase activity
IHV77_RS07680	COG0589	response to stress
IHV77_RS07695	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IHV77_RS07700	COG1368	sulfuric ester hydrolase activity
IHV77_RS07705	COG0066	3-isopropylmalate dehydratase activity
IHV77_RS07735	COG0758	DNA mediated transformation
IHV77_RS07755	COG1399	metal-binding, possibly nucleic acid-binding protein
IHV77_RS07775	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IHV77_RS07780	COG1028	Short-chain dehydrogenase reductase Sdr
IHV77_RS07790	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
IHV77_RS07795	COG0826	peptidase U32
IHV77_RS07810	COG2814	Major facilitator Superfamily
IHV77_RS07815	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IHV77_RS07820	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IHV77_RS07825	COG2252	PERMEase
IHV77_RS07845	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
IHV77_RS07850	COG1459	type II secretion system
IHV77_RS07855	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IHV77_RS07860	COG4969	Belongs to the N-Me-Phe pilin family
IHV77_RS07865	COG3023	N-Acetylmuramoyl-L-alanine amidase
IHV77_RS07885	COG0590	tRNA wobble adenosine to inosine editing
IHV77_RS07900	COG0481	GTPase activity
IHV77_RS07905	COG0681	Belongs to the peptidase S26 family
IHV77_RS07920	COG2801	Transposase and inactivated derivatives
IHV77_RS07925	COG2801	Transposase and inactivated derivatives
IHV77_RS07940	COG1194	a g-specific adenine glycosylase
IHV77_RS07965	COG0814	amino acid
IHV77_RS07970	COG1435	thymidine kinase activity
IHV77_RS07980	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IHV77_RS07990	COG0358	DNA primase activity
IHV77_RS07995	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IHV77_RS08000	COG0814	amino acid
IHV77_RS08005	COG1561	YicC-like family, N-terminal region
IHV77_RS08010	COG0354	folic acid binding
IHV77_RS08020	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IHV77_RS08025	COG0799	negative regulation of ribosome biogenesis
IHV77_RS08035	COG0768	penicillin binding
IHV77_RS08040	COG0772	Belongs to the SEDS family
IHV77_RS08045	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IHV77_RS08045	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IHV77_RS08050	COG1686	Belongs to the peptidase S11 family
IHV77_RS08075	COG4178	(ABC) transporter
IHV77_RS08080	COG1077	Cell shape determining protein MreB Mrl
IHV77_RS08085	COG1792	Involved in formation and maintenance of cell shape
IHV77_RS08090	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IHV77_RS08100	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IHV77_RS08135	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IHV77_RS08145	COG1252	NADH dehydrogenase
IHV77_RS08175	COG0659	secondary active sulfate transmembrane transporter activity
IHV77_RS08180	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IHV77_RS08190	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
IHV77_RS08195	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IHV77_RS08200	COG0110	maltose O-acetyltransferase activity
IHV77_RS08205	COG0110	maltose O-acetyltransferase activity
IHV77_RS08220	COG0110	maltose O-acetyltransferase activity
IHV77_RS08225	COG1733	regulation of RNA biosynthetic process
IHV77_RS08260	COG1902	pentaerythritol trinitrate reductase activity
IHV77_RS08265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IHV77_RS08300	COG0583	DNA-binding transcription factor activity
IHV77_RS08330	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IHV77_RS08350	COG2991	Protein conserved in bacteria
IHV77_RS08355	COG1477	protein flavinylation
IHV77_RS08375	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
IHV77_RS08390	COG0271	Belongs to the BolA IbaG family
IHV77_RS08395	COG3056	Lipoprotein
IHV77_RS08400	COG0598	Magnesium transport protein CorA
IHV77_RS08405	COG0762	integral membrane protein
IHV77_RS08410	COG1872	DUF167
IHV77_RS08420	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
IHV77_RS08425	COG1466	dna polymerase III delta subunit
IHV77_RS08430	COG0494	nUDIX hydrolase
IHV77_RS08435	COG0653	protein targeting
IHV77_RS08445	COG4701	Protein of unknown function (DUF721)
IHV77_RS08450	COG0338	D12 class N6 adenine-specific DNA methyltransferase
IHV77_RS08455	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IHV77_RS08480	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IHV77_RS08485	COG0629	single-stranded DNA binding
IHV77_RS08490	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IHV77_RS08495	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IHV77_RS08505	COG0560	Phosphoserine phosphatase
IHV77_RS08515	COG1115	amino acid carrier protein
IHV77_RS08520	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IHV77_RS08525	COG0513	Belongs to the DEAD box helicase family
IHV77_RS08535	COG0754	glutathionylspermidine amidase activity
IHV77_RS08545	COG1011	Hydrolase
IHV77_RS08550	COG4316	Uncharacterized protein conserved in bacteria (DUF2251)
IHV77_RS08560	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IHV77_RS08570	COG0180	Tryptophanyl-tRNA synthetase
IHV77_RS08575	COG3691	Protein conserved in bacteria
IHV77_RS08585	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IHV77_RS08590	COG3719	Belongs to the RNase T2 family
IHV77_RS08600	COG0191	fructose-bisphosphate aldolase activity
IHV77_RS08605	COG3307	-O-antigen
IHV77_RS08610	COG0859	PFAM glycosyl transferase family 9
IHV77_RS08615	COG2364	Membrane
IHV77_RS08620	COG1328	CTP reductase activity
IHV77_RS08635	COG0471	metal ion transport
IHV77_RS08640	COG2828	Protein conserved in bacteria
IHV77_RS08650	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IHV77_RS08660	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IHV77_RS08665	COG1441	menaquinone biosynthetic process
IHV77_RS08675	COG0511	ligase activity, forming carbon-carbon bonds
IHV77_RS08680	COG0439	Biotin carboxylase
IHV77_RS08690	COG1349	DNA-binding transcription factor activity
IHV77_RS08695	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
IHV77_RS08700	COG1070	Carbohydrate kinase
IHV77_RS08710	COG0235	Class ii aldolase
IHV77_RS08715	COG0738	Major facilitator superfamily
IHV77_RS08720	COG3005	denitrification pathway
IHV77_RS08725	COG0243	molybdopterin cofactor binding
IHV77_RS08730	COG0504	CTP synthase activity
IHV77_RS08740	COG1114	Component of the transport system for branched-chain amino acids
IHV77_RS08745	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IHV77_RS08750	COG0557	exoribonuclease II activity
IHV77_RS08785	COG0583	DNA-binding transcription factor activity
IHV77_RS08790	COG0564	pseudouridine synthase activity
IHV77_RS08800	COG3201	nicotinamide mononucleotide transporter
IHV77_RS08815	COG1476	TRANSCRIPTIONal
IHV77_RS08820	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
IHV77_RS08825	COG0513	Belongs to the DEAD box helicase family
IHV77_RS08835	COG0728	peptidoglycan biosynthetic process
IHV77_RS08840	COG0196	riboflavin kinase activity
IHV77_RS08860	COG4206	TonB-dependent receptor
IHV77_RS08865	COG0752	glycyl-tRNA synthetase alpha subunit
IHV77_RS08875	COG4545	Glutaredoxin-related protein
IHV77_RS08880	COG0751	glycine-tRNA ligase activity
IHV77_RS08895	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IHV77_RS08895	COG0475	glutathione-regulated potassium exporter activity
IHV77_RS08900	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IHV77_RS08905	COG3642	lipopolysaccharide core region biosynthetic process
IHV77_RS08910	COG0859	PFAM glycosyl transferase family 9
IHV77_RS08915	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IHV77_RS08920	COG4977	sequence-specific DNA binding
IHV77_RS08920	COG1917	Cupin 2, conserved barrel domain protein
IHV77_RS08925	COG1132	(ABC) transporter
IHV77_RS08930	COG2963	transposase activity
IHV77_RS08935	COG2801	Transposase and inactivated derivatives
IHV77_RS08940	COG2801	Transposase and inactivated derivatives
IHV77_RS08945	COG3691	Protein conserved in bacteria
IHV77_RS08955	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IHV77_RS08965	COG2095	MarC family integral membrane protein
IHV77_RS08975	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
IHV77_RS08985	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IHV77_RS08990	COG1121	(ABC) transporter
IHV77_RS08995	COG0739	heme binding
IHV77_RS09000	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IHV77_RS09005	COG4605	iron ion homeostasis
IHV77_RS09010	COG4604	ABC transporter, ATP-binding protein
IHV77_RS09015	COG4607	ABC-type enterochelin transport system periplasmic component
IHV77_RS09020	COG3283	Transcriptional regulator of aromatic amino acids metabolism
IHV77_RS09025	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IHV77_RS09030	COG1923	regulation of RNA biosynthetic process
IHV77_RS09035	COG0564	pseudouridine synthase activity
IHV77_RS09040	COG1530	ribonuclease E activity
IHV77_RS09055	COG2056	Na+-H+ antiporter family
IHV77_RS09060	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IHV77_RS09065	COG0346	lactoylglutathione lyase activity
IHV77_RS09075	COG1755	Isoprenylcysteine carboxyl methyltransferase
IHV77_RS09090	COG0494	nUDIX hydrolase
IHV77_RS09095	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IHV77_RS09100	COG0217	transcriptional regulatory protein
IHV77_RS09125	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IHV77_RS09140	COG1126	abc transporter atp-binding protein
IHV77_RS09145	COG0765	amino acid transport
IHV77_RS09150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IHV77_RS09200	COG0702	epimerase
IHV77_RS09205	COG1733	regulation of RNA biosynthetic process
IHV77_RS09220	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IHV77_RS09225	COG3068	Protein conserved in bacteria
IHV77_RS09230	COG0776	regulation of translation
IHV77_RS09235	COG1349	DNA-binding transcription factor activity
IHV77_RS09240	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IHV77_RS09245	COG3850	Histidine kinase
IHV77_RS09250	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IHV77_RS09255	COG1027	Aspartate ammonia-lyase
IHV77_RS09260	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IHV77_RS09275	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IHV77_RS09285	COG1271	oxidase subunit
IHV77_RS09290	COG1294	oxidase, subunit
IHV77_RS09300	COG0824	Thioesterase
IHV77_RS09305	COG0811	peptide transport
IHV77_RS09310	COG0848	biopolymer transport protein
IHV77_RS09315	COG3064	Membrane
IHV77_RS09325	COG2885	chlorophyll binding
IHV77_RS09355	COG1944	ATP diphosphatase activity
IHV77_RS09375	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IHV77_RS09405	COG2801	Transposase and inactivated derivatives
IHV77_RS09430	COG0671	phosphoesterase, PA-phosphatase related
IHV77_RS09440	COG1115	amino acid carrier protein
IHV77_RS09470	COG2814	Major facilitator Superfamily
IHV77_RS09475	COG1187	pseudouridine synthase activity
IHV77_RS09480	COG3955	Domain of unknown function (DUF1919)
IHV77_RS09485	COG0281	malic enzyme
IHV77_RS09485	COG0280	phosphate acetyltransferase
IHV77_RS09495	COG0471	metal ion transport
IHV77_RS09500	COG0531	amino acid
IHV77_RS09505	COG1573	uracil-dna glycosylase
IHV77_RS09515	COG0012	GTP binding
IHV77_RS09520	COG0193	aminoacyl-tRNA hydrolase activity
IHV77_RS09535	COG2850	peptidyl-arginine hydroxylation
IHV77_RS09550	COG1793	dna ligase
IHV77_RS09560	COG1126	abc transporter atp-binding protein
IHV77_RS09565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IHV77_RS09570	COG4215	(ABC) transporter
IHV77_RS09575	COG4160	amino acid transport
IHV77_RS09585	COG1966	Carbon starvation protein
IHV77_RS09595	COG0275	rRNA processing
IHV77_RS09600	COG3116	cell division
IHV77_RS09605	COG0768	penicillin binding
IHV77_RS09615	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IHV77_RS09630	COG0772	Belongs to the SEDS family
IHV77_RS09635	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IHV77_RS09640	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IHV77_RS09650	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IHV77_RS09655	COG0849	cell division
IHV77_RS09660	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IHV77_RS09665	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
IHV77_RS09670	COG0737	Belongs to the 5'-nucleotidase family
IHV77_RS09675	COG0077	Prephenate dehydratase
IHV77_RS09675	COG1605	Chorismate mutase
IHV77_RS09750	COG0629	single-stranded DNA binding
IHV77_RS09875	COG3617	BRO family, N-terminal domain
IHV77_RS09890	COG3772	lysozyme
IHV77_RS09905	COG3646	Phage regulatory protein
IHV77_RS09910	COG3728	DNA packaging
IHV77_RS09935	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IHV77_RS10025	COG3617	BRO family, N-terminal domain
IHV77_RS10085	COG0582	viral genome integration into host DNA
IHV77_RS10100	COG0517	IMP dehydrogenase activity
IHV77_RS10100	COG0516	GMP reductase activity
IHV77_RS10105	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
IHV77_RS10105	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
IHV77_RS10135	COG1946	Acyl-CoA thioesterase
IHV77_RS10145	COG0405	Gamma-glutamyltransferase
IHV77_RS10160	COG2358	TRAP transporter, solute receptor (TAXI family
IHV77_RS10165	COG0583	DNA-binding transcription factor activity
IHV77_RS10170	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IHV77_RS10175	COG1687	branched-chain amino acid
IHV77_RS10180	COG3842	ATPase activity
IHV77_RS10200	COG1971	Probably functions as a manganese efflux pump
IHV77_RS10205	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IHV77_RS10210	COG3366	ferrous iron transmembrane transporter activity
IHV77_RS10220	COG0537	adenosine 5'-monophosphoramidase activity
IHV77_RS10225	COG5633	Lipoprotein
IHV77_RS10230	COG1472	Belongs to the glycosyl hydrolase 3 family
IHV77_RS10240	COG3730	PTS system glucitol sorbitol-specific
IHV77_RS10255	COG1028	Short-chain dehydrogenase reductase Sdr
IHV77_RS10260	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
IHV77_RS10265	COG1349	DNA-binding transcription factor activity
IHV77_RS10270	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IHV77_RS10275	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IHV77_RS10280	COG0512	Glutamine amidotransferase of anthranilate synthase
IHV77_RS10290	COG3091	SprT-like family
IHV77_RS10300	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IHV77_RS10305	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IHV77_RS10310	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IHV77_RS10320	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
IHV77_RS10325	COG1414	Transcriptional regulator
IHV77_RS10330	COG0326	Molecular chaperone. Has ATPase activity
IHV77_RS10335	COG1393	Belongs to the ArsC family
IHV77_RS10345	COG1876	peptidase activity
IHV77_RS10355	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IHV77_RS10360	COG1137	ATPase activity
IHV77_RS10365	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IHV77_RS10370	COG3117	lipopolysaccharide transmembrane transporter activity
IHV77_RS10380	COG0312	modulator of DNA gyrase
IHV77_RS10385	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
IHV77_RS10395	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IHV77_RS10400	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IHV77_RS10405	COG1121	(ABC) transporter
IHV77_RS10415	COG0612	Peptidase, M16
IHV77_RS10420	COG4771	TonB-dependent receptor
IHV77_RS10425	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
IHV77_RS10435	COG0732	type I restriction modification DNA specificity domain
IHV77_RS10445	COG1943	Transposase
IHV77_RS10455	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
IHV77_RS10460	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IHV77_RS10465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IHV77_RS10470	COG3105	Protein conserved in bacteria
IHV77_RS10475	COG0251	oxidation-reduction process
IHV77_RS10485	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
IHV77_RS10490	COG1368	sulfuric ester hydrolase activity
IHV77_RS10500	COG3021	interspecies interaction between organisms
IHV77_RS10510	COG3008	intermembrane lipid transfer
IHV77_RS10515	COG2995	paraquat-inducible protein a
IHV77_RS10520	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
IHV77_RS10525	COG0793	Belongs to the peptidase S41A family
IHV77_RS10530	COG2989	Protein conserved in bacteria
IHV77_RS10535	COG3108	Peptidase M15
IHV77_RS10540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IHV77_RS10550	COG3102	Protein conserved in bacteria
IHV77_RS10560	COG3133	Outer membrane lipoprotein
IHV77_RS10565	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IHV77_RS10570	COG0617	tRNA 3'-terminal CCA addition
IHV77_RS10575	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IHV77_RS10580	COG2333	competence protein COMEC
IHV77_RS10580	COG0658	competence protein
IHV77_RS10590	COG1663	tetraacyldisaccharide 4'-kinase activity
IHV77_RS10595	COG2835	tetraacyldisaccharide 4'-kinase activity
IHV77_RS10610	COG0861	Integral membrane protein TerC family
IHV77_RS10615	COG0028	Belongs to the TPP enzyme family
IHV77_RS10620	COG0440	acetolactate synthase activity
IHV77_RS10640	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IHV77_RS10645	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IHV77_RS10650	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IHV77_RS10655	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IHV77_RS10660	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
IHV77_RS10665	COG0539	negative regulation of cytoplasmic translation
IHV77_RS10675	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
IHV77_RS10680	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
IHV77_RS10690	COG0023	Translation Initiation Factor
IHV77_RS10695	COG3094	Invasion gene expression up-regulator, SirB
IHV77_RS10715	COG0488	(ABC) transporter
IHV77_RS10720	COG3683	transport system, periplasmic component
IHV77_RS10725	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
IHV77_RS10740	COG0673	inositol 2-dehydrogenase activity
IHV77_RS10745	COG0673	inositol 2-dehydrogenase activity
IHV77_RS10750	COG2186	Transcriptional regulator
IHV77_RS10755	COG2814	Major facilitator Superfamily
IHV77_RS10765	COG0469	pyruvate kinase activity
IHV77_RS10770	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
IHV77_RS10775	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
IHV77_RS10780	COG0789	Transcriptional regulator
IHV77_RS10785	COG5266	PFAM Nickel transport complex, NikM subunit, transmembrane
IHV77_RS10790	COG0310	cobalt ion transport
IHV77_RS10795	COG0310	cobalt ion transport
IHV77_RS10800	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IHV77_RS10805	COG1122	ATPase activity
IHV77_RS10815	COG0795	lipopolysaccharide-transporting ATPase activity
IHV77_RS10820	COG0795	lipopolysaccharide-transporting ATPase activity
IHV77_RS10845	COG0527	aspartate kinase activity
IHV77_RS10850	COG2949	membrane
IHV77_RS10855	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IHV77_RS10860	COG0778	Nitroreductase
IHV77_RS10865	COG0616	signal peptide processing
IHV77_RS10870	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IHV77_RS10880	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IHV77_RS10895	COG0385	Bile acid
IHV77_RS10900	COG4172	Belongs to the ABC transporter superfamily
IHV77_RS10905	COG4172	Belongs to the ABC transporter superfamily
IHV77_RS10910	COG4171	peptide transport system, permease
IHV77_RS10915	COG4168	peptide transport system, permease
IHV77_RS10920	COG4166	transmembrane transport
IHV77_RS10925	COG3106	COG3106 Predicted ATPase
IHV77_RS10930	COG2990	Protein conserved in bacteria
IHV77_RS10945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IHV77_RS10955	COG1120	ATPase activity
IHV77_RS10965	COG0564	pseudouridine synthase activity
IHV77_RS10970	COG0708	Exodeoxyribonuclease III
IHV77_RS10975	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
IHV77_RS10980	COG0778	Nitroreductase
IHV77_RS10990	COG1621	beta-fructofuranosidase activity
IHV77_RS11000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IHV77_RS11015	COG2169	Transcriptional regulator
IHV77_RS11020	COG2211	Major facilitator Superfamily
IHV77_RS11030	COG0676	glucose-6-phosphate 1-epimerase activity
IHV77_RS11040	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IHV77_RS11045	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IHV77_RS11050	COG0488	(ABC) transporter
IHV77_RS11055	COG0733	neurotransmitter:sodium symporter activity
IHV77_RS11060	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IHV77_RS11070	COG4659	FMN binding
IHV77_RS11080	COG4656	Part of a membrane complex involved in electron transport
IHV77_RS11090	COG4657	Part of a membrane complex involved in electron transport
IHV77_RS11110	COG0732	type I restriction modification DNA specificity domain
IHV77_RS11115	COG2184	nucleotidyltransferase activity
IHV77_RS11125	COG1289	transmembrane transporter activity
IHV77_RS11135	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
IHV77_RS11140	COG1984	allophanate hydrolase subunit 2
IHV77_RS11145	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
IHV77_RS11150	COG1914	H( )-stimulated, divalent metal cation uptake system
IHV77_RS11165	COG3098	single-species biofilm formation
IHV77_RS11170	COG0564	pseudouridine synthase activity
IHV77_RS11175	COG3140	Belongs to the UPF0181 family
IHV77_RS11180	COG1278	Cold shock
IHV77_RS11190	COG1067	ATP-dependent peptidase activity
IHV77_RS11195	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IHV77_RS11200	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IHV77_RS11205	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IHV77_RS11210	COG2252	PERMEase
IHV77_RS11215	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
IHV77_RS11230	COG1074	ATP-dependent DNA helicase activity
IHV77_RS11235	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IHV77_RS11240	COG2999	glutathione oxidoreductase activity
IHV77_RS11245	COG0783	Belongs to the Dps family
IHV77_RS11260	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
IHV77_RS11280	COG0804	urea catabolic process
IHV77_RS11300	COG1448	Aminotransferase
IHV77_RS11305	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IHV77_RS11310	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IHV77_RS11315	COG0308	aminopeptidase N
IHV77_RS11330	COG0613	PHP domain protein
IHV77_RS11365	COG0489	protein tyrosine kinase activity
IHV77_RS11375	COG0463	Glycosyl transferase, family 2
IHV77_RS11385	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IHV77_RS11390	COG0517	IMP dehydrogenase activity
IHV77_RS11390	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IHV77_RS11400	COG2027	D-alanyl-D-alanine carboxypeptidase
IHV77_RS11405	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IHV77_RS11420	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IHV77_RS11425	COG1534	Rna-binding protein
IHV77_RS11435	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IHV77_RS11440	COG0583	DNA-binding transcription factor activity
IHV77_RS11445	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IHV77_RS11450	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IHV77_RS11455	COG2031	fatty acid transporter
IHV77_RS11460	COG0183	Belongs to the thiolase family
IHV77_RS11465	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IHV77_RS11470	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IHV77_RS11475	COG2062	phosphohistidine phosphatase, SixA
IHV77_RS11485	COG3100	YcgL domain-containing protein
IHV77_RS11490	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IHV77_RS11500	COG0288	reversible hydration of carbon dioxide
IHV77_RS11510	COG0616	signal peptide processing
IHV77_RS11525	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IHV77_RS11540	COG0791	NLP P60 protein
IHV77_RS11545	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IHV77_RS11560	COG0625	glutathione transferase activity
IHV77_RS11565	COG2969	positive regulation of protein catabolic process
IHV77_RS11570	COG0814	amino acid
IHV77_RS11580	COG0673	inositol 2-dehydrogenase activity
IHV77_RS11590	COG3962	Belongs to the TPP enzyme family
IHV77_RS11595	COG0477	Major facilitator Superfamily
IHV77_RS11595	COG2814	Major facilitator Superfamily
IHV77_RS11600	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IHV77_RS11605	COG1172	Belongs to the binding-protein-dependent transport system permease family
IHV77_RS11610	COG1129	ABC transporter
IHV77_RS11615	COG1879	ABC-type sugar transport system periplasmic component
IHV77_RS11620	COG0673	inositol 2-dehydrogenase activity
IHV77_RS11630	COG3718	enzyme involved in inositol metabolism
IHV77_RS11640	COG0753	catalase activity
IHV77_RS11650	COG0531	amino acid
IHV77_RS11660	COG0583	DNA-binding transcription factor activity
IHV77_RS11670	COG0508	dehydrogenase complex catalyzes the overall conversion of
IHV77_RS11685	COG4221	oxidoreductase activity
IHV77_RS11690	COG0135	phosphoribosylanthranilate isomerase activity
IHV77_RS11690	COG0134	indole-3-glycerol-phosphate synthase activity
IHV77_RS11700	COG1942	4-Oxalocrotonate Tautomerase
IHV77_RS11705	COG0512	Glutamine amidotransferase of anthranilate synthase
IHV77_RS11710	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IHV77_RS11715	COG3550	peptidyl-serine autophosphorylation
IHV77_RS11720	COG1396	sequence-specific DNA binding
IHV77_RS11735	COG3111	PFAM Bacterial OB fold (BOF) protein
IHV77_RS11740	COG0745	RESPONSE REGULATOR receiver
IHV77_RS11745	COG0642	Histidine kinase
IHV77_RS11755	COG0515	serine threonine protein kinase
IHV77_RS11770	COG0195	Participates in both transcription termination and antitermination
IHV77_RS11775	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IHV77_RS11805	COG0287	Prephenate dehydrogenase
IHV77_RS11805	COG1605	Chorismate mutase
IHV77_RS11810	COG1611	Belongs to the LOG family
IHV77_RS11815	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IHV77_RS11815	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)