locus-tag	class	description
UC8_RS00010	COG0592	DNA-directed DNA polymerase activity
UC8_RS00020	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
UC8_RS00040	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
UC8_RS00085	COG2815	serine threonine protein kinase
UC8_RS00085	COG0515	serine threonine protein kinase
UC8_RS00100	COG2205	protein histidine kinase activity
UC8_RS00100	COG3437	response regulator, receiver
UC8_RS00100	COG3850	Histidine kinase
UC8_RS00100	COG4999	Histidine kinase
UC8_RS00120	COG0653	protein targeting
UC8_RS00145	COG0673	inositol 2-dehydrogenase activity
UC8_RS00160	COG4948	Mandelate Racemase Muconate Lactonizing
UC8_RS00185	COG0702	epimerase
UC8_RS00190	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
UC8_RS00195	COG3119	arylsulfatase activity
UC8_RS00215	COG0484	heat shock protein binding
UC8_RS00220	COG1297	OPT oligopeptide transporter protein
UC8_RS00290	COG2815	serine threonine protein kinase
UC8_RS00290	COG0515	serine threonine protein kinase
UC8_RS00300	COG0011	TIGRFAM Protein of
UC8_RS00310	COG3119	arylsulfatase activity
UC8_RS00325	COG1819	glycosyl
UC8_RS00380	COG0667	Aldo Keto reductase
UC8_RS00385	COG1064	alcohol dehydrogenase
UC8_RS00430	COG3119	arylsulfatase activity
UC8_RS00485	COG5487	UPF0391 membrane protein
UC8_RS00525	COG1073	alpha beta
UC8_RS00595	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
UC8_RS00605	COG4948	Mandelate Racemase Muconate Lactonizing
UC8_RS00610	COG1073	alpha beta
UC8_RS00690	COG0400	carboxylic ester hydrolase activity
UC8_RS00740	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
UC8_RS00745	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
UC8_RS00765	COG0778	Nitroreductase
UC8_RS00775	COG1120	ATPase activity
UC8_RS00780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
UC8_RS00785	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
UC8_RS00790	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
UC8_RS00800	COG1492	cobalamin metabolic process
UC8_RS00895	COG3119	arylsulfatase activity
UC8_RS00905	COG2815	serine threonine protein kinase
UC8_RS00905	COG0515	serine threonine protein kinase
UC8_RS00940	COG0318	PFAM AMP-dependent synthetase and ligase
UC8_RS00950	COG0477	Major facilitator Superfamily
UC8_RS00955	COG2124	cytochrome p450
UC8_RS00970	COG3848	Pyruvate phosphate dikinase
UC8_RS00970	COG0574	Belongs to the PEP-utilizing enzyme family
UC8_RS00975	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
UC8_RS00980	COG3408	Glycogen debranching enzyme
UC8_RS00980	COG3119	arylsulfatase activity
UC8_RS00990	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
UC8_RS00995	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
UC8_RS01000	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
UC8_RS01010	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
UC8_RS01015	COG3119	arylsulfatase activity
UC8_RS01100	COG0673	inositol 2-dehydrogenase activity
UC8_RS01105	COG3119	arylsulfatase activity
UC8_RS01130	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
UC8_RS01145	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
UC8_RS01170	COG0693	protein deglycase activity
UC8_RS01175	COG0436	Aminotransferase
UC8_RS01205	COG1082	Xylose isomerase domain protein TIM barrel
UC8_RS01230	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
UC8_RS01255	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
UC8_RS01260	COG1053	succinate dehydrogenase
UC8_RS01275	COG0508	dehydrogenase complex catalyzes the overall conversion of
UC8_RS01285	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
UC8_RS01290	COG0189	ligase activity
UC8_RS01290	COG0569	domain protein
UC8_RS01325	COG0750	zinc metalloprotease
UC8_RS01325	COG0750	zinc metalloprotease
UC8_RS01330	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
UC8_RS01335	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
UC8_RS01340	COG1082	Xylose isomerase domain protein TIM barrel
UC8_RS01400	COG2207	Transcriptional regulator
UC8_RS01400	COG1609	Transcriptional regulator
UC8_RS01440	COG0142	geranyltranstransferase activity
UC8_RS01455	COG0626	cystathionine gamma-synthase activity
UC8_RS01470	COG2815	serine threonine protein kinase
UC8_RS01470	COG0515	serine threonine protein kinase
UC8_RS01480	COG0673	inositol 2-dehydrogenase activity
UC8_RS01490	COG4585	Histidine kinase
UC8_RS01495	COG2197	response regulator
UC8_RS01510	COG0019	diaminopimelate decarboxylase activity
UC8_RS01520	COG3119	arylsulfatase activity
UC8_RS01540	COG1595	DNA-templated transcription, initiation
UC8_RS01555	COG2204	response regulator
UC8_RS01560	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
UC8_RS01575	COG0439	Biotin carboxylase
UC8_RS01580	COG0511	ligase activity, forming carbon-carbon bonds
UC8_RS01600	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
UC8_RS01615	COG0564	pseudouridine synthase activity
UC8_RS01620	COG3273	potassium ion transport
UC8_RS01620	COG0471	metal ion transport
UC8_RS01630	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
UC8_RS01640	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
UC8_RS01645	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
UC8_RS01650	COG0815	Transfers the fatty acyl group on membrane lipoproteins
UC8_RS01655	COG1199	ATP-dependent helicase activity
UC8_RS01660	COG0758	DNA mediated transformation
UC8_RS01660	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
UC8_RS01675	COG0066	3-isopropylmalate dehydratase activity
UC8_RS01680	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
UC8_RS01695	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
UC8_RS01725	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
UC8_RS01735	COG3724	N-succinylarginine dihydrolase activity
UC8_RS01755	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
UC8_RS01775	COG0277	FAD linked oxidase domain protein
UC8_RS01775	COG0247	lactate metabolic process
UC8_RS01780	COG2755	lipolytic protein G-D-S-L family
UC8_RS01780	COG0657	acetylesterase activity
UC8_RS01815	COG1136	(ABC) transporter
UC8_RS01880	COG3119	arylsulfatase activity
UC8_RS01905	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
UC8_RS01905	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
UC8_RS01940	COG0174	glutamine synthetase
UC8_RS01945	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
UC8_RS01950	COG0673	inositol 2-dehydrogenase activity
UC8_RS01965	COG0515	serine threonine protein kinase
UC8_RS01965	COG2815	serine threonine protein kinase
UC8_RS01980	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
UC8_RS02000	COG3119	arylsulfatase activity
UC8_RS02010	COG4968	Prepilin-type N-terminal cleavage methylation domain
UC8_RS02045	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
UC8_RS02050	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
UC8_RS02055	COG1560	Kdo2-lipid A biosynthetic process
UC8_RS02060	COG1473	amidohydrolase
UC8_RS02065	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
UC8_RS02070	COG2815	serine threonine protein kinase
UC8_RS02070	COG0515	serine threonine protein kinase
UC8_RS02075	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
UC8_RS02085	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
UC8_RS02105	COG2409	Drug exporters of the RND superfamily
UC8_RS02115	COG3590	peptidase
UC8_RS02125	COG0714	Associated with various cellular activities
UC8_RS02145	COG0812	UDP-N-acetylmuramate dehydrogenase activity
UC8_RS02170	COG2877	3-deoxy-8-phosphooctulonate synthase activity
UC8_RS02185	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
UC8_RS02190	COG2258	MOSC domain
UC8_RS02225	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
UC8_RS02225	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
UC8_RS02235	COG1459	type II secretion system
UC8_RS02240	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
UC8_RS02265	COG0826	peptidase U32
UC8_RS02285	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
UC8_RS02290	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
UC8_RS02300	COG1758	RNA polymerase activity
UC8_RS02305	COG0194	GDP metabolic process
UC8_RS02310	COG1561	YicC-like family, N-terminal region
UC8_RS02320	COG0149	triose-phosphate isomerase activity
UC8_RS02325	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
UC8_RS02355	COG2022	thiamine diphosphate biosynthetic process
UC8_RS02395	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
UC8_RS02400	COG0358	DNA primase activity
UC8_RS02410	COG1045	serine acetyltransferase
UC8_RS02415	COG2852	Protein conserved in bacteria
UC8_RS02425	COG0295	cytidine deaminase activity
UC8_RS02435	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
UC8_RS02440	COG4956	integral membrane protein (PIN domain superfamily)
UC8_RS02445	COG0515	serine threonine protein kinase
UC8_RS02455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
UC8_RS02475	COG0318	PFAM AMP-dependent synthetase and ligase
UC8_RS02480	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
UC8_RS02485	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
UC8_RS02495	COG0820	rRNA (adenine-C2-)-methyltransferase activity
UC8_RS02505	COG2195	Cleaves the N-terminal amino acid of tripeptides
UC8_RS02530	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
UC8_RS02535	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
UC8_RS02540	COG1132	(ABC) transporter
UC8_RS02550	COG0788	formyltetrahydrofolate deformylase activity
UC8_RS02560	COG0124	histidyl-tRNA synthetase
UC8_RS02575	COG2199	diguanylate cyclase activity
UC8_RS02575	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
UC8_RS02580	COG0745	RESPONSE REGULATOR receiver
UC8_RS02590	COG2205	protein histidine kinase activity
UC8_RS02615	COG1459	type II secretion system
UC8_RS02620	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
UC8_RS02680	COG0714	Associated with various cellular activities
UC8_RS02785	COG0438	transferase activity, transferring glycosyl groups
UC8_RS02795	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
UC8_RS02810	COG0443	Heat shock 70 kDa protein
UC8_RS02815	COG0443	Heat shock 70 kDa protein
UC8_RS02840	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
UC8_RS02845	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
UC8_RS02850	COG3119	arylsulfatase activity
UC8_RS02855	COG3119	arylsulfatase activity
UC8_RS02870	COG3119	arylsulfatase activity
UC8_RS02880	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
UC8_RS02890	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
UC8_RS02895	COG0571	ribonuclease III activity
UC8_RS02900	COG1028	Short-chain dehydrogenase reductase Sdr
UC8_RS02915	COG0489	protein tyrosine kinase activity
UC8_RS02955	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
UC8_RS02965	COG0110	maltose O-acetyltransferase activity
UC8_RS02985	COG0275	rRNA processing
UC8_RS02990	COG0438	transferase activity, transferring glycosyl groups
UC8_RS02995	COG0367	asparagine synthase
UC8_RS03005	COG1216	Glycosyl transferase, family 2
UC8_RS03035	COG0367	asparagine synthase
UC8_RS03040	COG0438	transferase activity, transferring glycosyl groups
UC8_RS03100	COG1191	sigma factor activity
UC8_RS03110	COG1506	peptidase
UC8_RS03110	COG0823	Involved in the tonB-independent uptake of proteins
UC8_RS03160	COG0848	biopolymer transport protein
UC8_RS03165	COG0811	peptide transport
UC8_RS03180	COG4869	propanediol catabolic process
UC8_RS03190	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
UC8_RS03195	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
UC8_RS03200	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
UC8_RS03225	COG0235	Class ii aldolase
UC8_RS03230	COG0039	L-malate dehydrogenase activity
UC8_RS03235	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
UC8_RS03260	COG0514	ATP-dependent DNA helicase (RecQ)
UC8_RS03270	COG0514	ATP-dependent DNA helicase (RecQ)
UC8_RS03290	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
UC8_RS03310	COG4251	negative regulation of phosphorylation
UC8_RS03315	COG2197	response regulator
UC8_RS03320	COG0515	serine threonine protein kinase
UC8_RS03320	COG2815	serine threonine protein kinase
UC8_RS03350	COG2204	response regulator
UC8_RS03375	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
UC8_RS03385	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
UC8_RS03395	COG0517	IMP dehydrogenase activity
UC8_RS03395	COG1994	Peptidase M50
UC8_RS03410	COG2135	peptidase activity
UC8_RS03430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
UC8_RS03435	COG1914	H( )-stimulated, divalent metal cation uptake system
UC8_RS03460	COG0047	phosphoribosylformylglycinamidine synthase activity
UC8_RS03475	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
UC8_RS03490	COG1185	polyribonucleotide nucleotidyltransferase activity
UC8_RS03495	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
UC8_RS03500	COG0330	HflC and HflK could
UC8_RS03505	COG0330	HflC and HflK could
UC8_RS03550	COG3958	Transketolase
UC8_RS03560	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
UC8_RS03580	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
UC8_RS03585	COG0745	RESPONSE REGULATOR receiver
UC8_RS03655	COG0552	protein localization to endoplasmic reticulum
UC8_RS03665	COG0656	L-ascorbic acid biosynthetic process
UC8_RS03680	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
UC8_RS03685	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
UC8_RS03700	COG1131	(ABC) transporter
UC8_RS03715	COG0693	protein deglycase activity
UC8_RS03720	COG0673	inositol 2-dehydrogenase activity
UC8_RS03725	COG0737	Belongs to the 5'-nucleotidase family
UC8_RS03745	COG3685	Protein conserved in bacteria
UC8_RS03755	COG3932	Exopolysaccharide synthesis, ExoD
UC8_RS03775	COG4585	Histidine kinase
UC8_RS03785	COG2197	response regulator
UC8_RS03795	COG2205	protein histidine kinase activity
UC8_RS03795	COG2198	Histidine kinase
UC8_RS03795	COG0784	Response regulator, receiver
UC8_RS03805	COG1449	Belongs to the glycosyl hydrolase 57 family
UC8_RS03815	COG0297	glycogen (starch) synthase activity
UC8_RS03865	COG1331	Highly conserved protein containing a thioredoxin domain
UC8_RS03885	COG1247	-acetyltransferase
UC8_RS03890	COG1858	cytochrome C peroxidase
UC8_RS03895	COG2211	Major facilitator Superfamily
UC8_RS03950	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
UC8_RS03960	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
UC8_RS03965	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
UC8_RS03995	COG3118	belongs to the thioredoxin family
UC8_RS04000	COG0714	Associated with various cellular activities
UC8_RS04030	COG0644	oxidoreductase
UC8_RS04045	COG1181	Belongs to the D-alanine--D-alanine ligase family
UC8_RS04060	COG2003	Belongs to the UPF0758 family
UC8_RS04075	COG1448	Aminotransferase
UC8_RS04100	COG0235	Class ii aldolase
UC8_RS04110	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
UC8_RS04115	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
UC8_RS04140	COG2084	Dehydrogenase
UC8_RS04150	COG0606	chelatase, subunit chli
UC8_RS04160	COG3119	arylsulfatase activity
UC8_RS04170	COG2032	superoxide dismutase activity
UC8_RS04180	COG2212	antiporter activity
UC8_RS04185	COG1320	monovalent cation:proton antiporter activity
UC8_RS04205	COG0651	ATP synthesis coupled electron transport
UC8_RS04210	COG0651	ATP synthesis coupled electron transport
UC8_RS04220	COG0651	ATP synthesis coupled electron transport
UC8_RS04225	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
UC8_RS04235	COG0464	growth
UC8_RS04245	COG3119	arylsulfatase activity
UC8_RS04255	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
UC8_RS04265	COG1120	ATPase activity
UC8_RS04335	COG3119	arylsulfatase activity
UC8_RS04405	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
UC8_RS04435	COG0673	inositol 2-dehydrogenase activity
UC8_RS04450	COG0612	Peptidase, M16
UC8_RS04460	COG1164	Oligoendopeptidase f
UC8_RS04465	COG1229	Formylmethanofuran dehydrogenase subunit A
UC8_RS04470	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
UC8_RS04495	COG3123	guanosine phosphorylase activity
UC8_RS04505	COG3119	arylsulfatase activity
UC8_RS04565	COG0367	asparagine synthase
UC8_RS04585	COG2192	nodulation
UC8_RS04590	COG0438	transferase activity, transferring glycosyl groups
UC8_RS04595	COG0367	asparagine synthase
UC8_RS04635	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
UC8_RS04640	COG0494	nUDIX hydrolase
UC8_RS04660	COG3321	synthase
UC8_RS04660	COG1028	Short-chain dehydrogenase reductase Sdr
UC8_RS04660	COG0604	alcohol dehydrogenase
UC8_RS04670	COG0717	Belongs to the dCTP deaminase family
UC8_RS04675	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
UC8_RS04680	COG0302	gtp cyclohydrolase
UC8_RS04700	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
UC8_RS04725	COG0405	Gamma-glutamyltransferase
UC8_RS04740	COG0463	Glycosyl transferase, family 2
UC8_RS04775	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
UC8_RS04795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
UC8_RS04810	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
UC8_RS04820	COG1131	(ABC) transporter
UC8_RS04830	COG0347	Belongs to the P(II) protein family
UC8_RS04850	COG1692	metallophosphoesterase
UC8_RS04855	COG1418	mRNA catabolic process
UC8_RS04860	COG0037	tRNA processing
UC8_RS04865	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
UC8_RS04870	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
UC8_RS04875	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
UC8_RS04880	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
UC8_RS04885	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
UC8_RS04925	COG0673	inositol 2-dehydrogenase activity
UC8_RS04970	COG2223	nitrite transmembrane transporter activity
UC8_RS04985	COG3119	arylsulfatase activity
UC8_RS04990	COG1538	Outer membrane efflux protein
UC8_RS05025	COG5002	protein histidine kinase activity
UC8_RS05030	COG0745	RESPONSE REGULATOR receiver
UC8_RS05060	COG0501	Belongs to the peptidase M48B family
UC8_RS05080	COG2912	Transglutaminase-like superfamily
UC8_RS05140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
UC8_RS05145	COG1879	ABC-type sugar transport system periplasmic component
UC8_RS05150	COG1129	ABC transporter
UC8_RS05155	COG1172	Belongs to the binding-protein-dependent transport system permease family
UC8_RS05255	COG0604	alcohol dehydrogenase
UC8_RS05265	COG1028	Short-chain dehydrogenase reductase Sdr
UC8_RS05310	COG3119	arylsulfatase activity
UC8_RS05325	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
UC8_RS05340	COG3119	arylsulfatase activity
UC8_RS05345	COG3119	arylsulfatase activity
UC8_RS05355	COG0686	Belongs to the AlaDH PNT family
UC8_RS05365	COG0275	rRNA processing
UC8_RS05380	COG0004	ammonium transporteR
UC8_RS05385	COG0545	Peptidyl-prolyl cis-trans isomerase
UC8_RS05395	COG0189	ligase activity
UC8_RS05395	COG4067	protein conserved in archaea
UC8_RS05400	COG0569	domain protein
UC8_RS05400	COG0189	ligase activity
UC8_RS05410	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
UC8_RS05415	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
UC8_RS05435	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
UC8_RS05440	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
UC8_RS05445	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
UC8_RS05455	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
UC8_RS05460	COG1595	DNA-templated transcription, initiation
UC8_RS05465	COG0750	zinc metalloprotease
UC8_RS05470	COG0456	acetyltransferase
UC8_RS05485	COG2384	SAM-dependent methyltransferase
UC8_RS05505	COG4335	DNA alkylation repair
UC8_RS05510	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
UC8_RS05525	COG2271	Major facilitator Superfamily
UC8_RS05535	COG1278	Cold shock
UC8_RS05560	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
UC8_RS05635	COG3119	arylsulfatase activity
UC8_RS05640	COG0667	Aldo Keto reductase
UC8_RS05655	COG0515	serine threonine protein kinase
UC8_RS05655	COG2815	serine threonine protein kinase
UC8_RS05685	COG2985	domain, Protein
UC8_RS05690	COG3119	arylsulfatase activity
UC8_RS05720	COG0540	Belongs to the ATCase OTCase family
UC8_RS05725	COG0367	asparagine synthase
UC8_RS05735	COG1335	isochorismatase
UC8_RS05750	COG0747	negative chemotaxis
UC8_RS05820	COG0714	Associated with various cellular activities
UC8_RS05825	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
UC8_RS05835	COG3119	arylsulfatase activity
UC8_RS05855	COG0725	ABC transporter, periplasmic molybdate-binding protein
UC8_RS05860	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
UC8_RS05875	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
UC8_RS05900	COG0514	ATP-dependent DNA helicase (RecQ)
UC8_RS05905	COG1216	Glycosyl transferase, family 2
UC8_RS05915	COG0297	glycogen (starch) synthase activity
UC8_RS05925	COG0534	Mate efflux family protein
UC8_RS05935	COG4628	conserved protein (DUF2132)
UC8_RS05945	COG3119	arylsulfatase activity
UC8_RS05960	COG3119	arylsulfatase activity
UC8_RS05965	COG0673	inositol 2-dehydrogenase activity
UC8_RS05980	COG2815	serine threonine protein kinase
UC8_RS05980	COG0515	serine threonine protein kinase
UC8_RS06045	COG4948	Mandelate Racemase Muconate Lactonizing
UC8_RS06050	COG2207	Transcriptional regulator
UC8_RS06050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
UC8_RS06060	COG3263	regulation of cellular component size
UC8_RS06110	COG3119	arylsulfatase activity
UC8_RS06120	COG3119	arylsulfatase activity
UC8_RS06180	COG0784	Response regulator, receiver
UC8_RS06180	COG2205	protein histidine kinase activity
UC8_RS06290	COG2207	Transcriptional regulator
UC8_RS06290	COG1609	Transcriptional regulator
UC8_RS06395	COG0515	serine threonine protein kinase
UC8_RS06395	COG2815	serine threonine protein kinase
UC8_RS06400	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
UC8_RS06405	COG2234	aminopeptidase activity
UC8_RS06420	COG1028	Short-chain dehydrogenase reductase Sdr
UC8_RS06500	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
UC8_RS06535	COG0457	Tetratricopeptide repeat
UC8_RS06790	COG3541	Predicted nucleotidyltransferase
UC8_RS06815	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
UC8_RS06835	COG1131	(ABC) transporter
UC8_RS06845	COG1131	(ABC) transporter
UC8_RS06855	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
UC8_RS06860	COG0154	amidase activity
UC8_RS06865	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
UC8_RS06870	COG0227	Belongs to the bacterial ribosomal protein bL28 family
UC8_RS06900	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
UC8_RS06965	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
UC8_RS07005	COG3852	Histidine kinase
UC8_RS07010	COG2204	response regulator
UC8_RS07020	COG3386	PFAM SMP-30 Gluconolaconase
UC8_RS07045	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
UC8_RS07050	COG2239	Acts as a magnesium transporter
UC8_RS07065	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
UC8_RS07105	COG5002	protein histidine kinase activity
UC8_RS07110	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
UC8_RS07160	COG1335	isochorismatase
UC8_RS07170	COG1196	nuclear chromosome segregation
UC8_RS07205	COG0232	Belongs to the dGTPase family. Type 2 subfamily
UC8_RS07220	COG4948	Mandelate Racemase Muconate Lactonizing
UC8_RS07235	COG0004	ammonium transporteR
UC8_RS07265	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
UC8_RS07280	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
UC8_RS07295	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
UC8_RS07300	COG0745	RESPONSE REGULATOR receiver
UC8_RS07305	COG2205	protein histidine kinase activity
UC8_RS07310	COG2304	oxidoreductase activity
UC8_RS07350	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
UC8_RS07355	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
UC8_RS07360	COG0085	RNA polymerase activity
UC8_RS07365	COG0222	ribosome binding
UC8_RS07370	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
UC8_RS07375	COG0081	regulation of translation
UC8_RS07380	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
UC8_RS07400	COG0724	RNA recognition motif
UC8_RS07415	COG1546	Belongs to the CinA family
UC8_RS07415	COG1058	Belongs to the CinA family
UC8_RS07440	COG0310	cobalt ion transport
UC8_RS07445	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
UC8_RS07460	COG0200	Binds to the 23S rRNA
UC8_RS07465	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
UC8_RS07470	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
UC8_RS07475	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
UC8_RS07480	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
UC8_RS07485	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
UC8_RS07490	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
UC8_RS07495	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
UC8_RS07500	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
UC8_RS07505	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
UC8_RS07510	COG0255	Belongs to the universal ribosomal protein uL29 family
UC8_RS07515	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
UC8_RS07520	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
UC8_RS07525	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
UC8_RS07530	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
UC8_RS07535	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
UC8_RS07540	COG0089	rRNA binding
UC8_RS07545	COG0088	Forms part of the polypeptide exit tunnel
UC8_RS07550	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
UC8_RS07555	COG0051	transcription antitermination factor activity, RNA binding
UC8_RS07675	COG1136	(ABC) transporter
UC8_RS07680	COG0577	efflux transmembrane transporter activity
UC8_RS07680	COG1136	(ABC) transporter
UC8_RS07685	COG0205	6-phosphofructokinase activity
UC8_RS07690	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
UC8_RS07695	COG0515	serine threonine protein kinase
UC8_RS07695	COG2815	serine threonine protein kinase
UC8_RS07720	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
UC8_RS07745	COG0708	Exodeoxyribonuclease III
UC8_RS07755	COG0166	Belongs to the GPI family
UC8_RS07760	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
UC8_RS07765	COG0237	dephospho-CoA kinase activity
UC8_RS07770	COG0261	This protein binds to 23S rRNA in the presence of protein L20
UC8_RS07800	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
UC8_RS07805	COG0581	inorganic phosphate transmembrane transporter activity
UC8_RS07810	COG0573	inorganic phosphate transmembrane transporter activity
UC8_RS07825	COG2226	methyltransferase
UC8_RS07835	COG0398	Pfam SNARE associated Golgi protein
UC8_RS07885	COG1136	(ABC) transporter
UC8_RS07885	COG0577	efflux transmembrane transporter activity
UC8_RS07890	COG1136	(ABC) transporter
UC8_RS07890	COG0577	efflux transmembrane transporter activity
UC8_RS07895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
UC8_RS07910	COG0745	RESPONSE REGULATOR receiver
UC8_RS07915	COG2205	protein histidine kinase activity
UC8_RS07950	COG0673	inositol 2-dehydrogenase activity
UC8_RS08010	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
UC8_RS08010	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
UC8_RS08035	COG4260	virion core protein, lumpy skin disease virus
UC8_RS08040	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
UC8_RS08055	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
UC8_RS08070	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
UC8_RS08075	COG0589	response to stress
UC8_RS08085	COG2204	response regulator
UC8_RS08090	COG3852	Histidine kinase
UC8_RS08095	COG3852	Histidine kinase
UC8_RS08100	COG4191	Histidine kinase
UC8_RS08140	COG1725	Transcriptional regulator
UC8_RS08145	COG1131	(ABC) transporter
UC8_RS08175	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
UC8_RS08180	COG0347	Belongs to the P(II) protein family
UC8_RS08185	COG3119	arylsulfatase activity
UC8_RS08200	COG1104	cysteine desulfurase activity
UC8_RS08215	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
UC8_RS08220	COG0440	acetolactate synthase activity
UC8_RS08225	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
UC8_RS08260	COG0848	biopolymer transport protein
UC8_RS08270	COG2321	neutral zinc metallopeptidase
UC8_RS08275	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
UC8_RS08285	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
UC8_RS08300	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
UC8_RS08310	COG0484	heat shock protein binding
UC8_RS08315	COG0594	ribonuclease P activity
UC8_RS08330	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
UC8_RS08340	COG0134	indole-3-glycerol-phosphate synthase activity
UC8_RS08345	COG0138	bifunctional purine biosynthesis protein purh
UC8_RS08380	COG1716	ATPase activity
UC8_RS08390	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
UC8_RS08400	COG2094	Belongs to the DNA glycosylase MPG family
UC8_RS08405	COG0402	S-adenosylhomocysteine deaminase activity
UC8_RS08420	COG0659	secondary active sulfate transmembrane transporter activity
UC8_RS08425	COG0457	Tetratricopeptide repeat
UC8_RS08425	COG0515	serine threonine protein kinase
UC8_RS08435	COG3119	arylsulfatase activity
UC8_RS08440	COG3119	arylsulfatase activity
UC8_RS08475	COG1136	(ABC) transporter
UC8_RS08490	COG3264	Mechanosensitive ion channel
UC8_RS08490	COG1511	domain protein
UC8_RS08535	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
UC8_RS08540	COG3408	Glycogen debranching enzyme
UC8_RS08540	COG3119	arylsulfatase activity
UC8_RS08540	COG3408	Glycogen debranching enzyme
UC8_RS08540	COG3119	arylsulfatase activity
UC8_RS08550	COG1131	(ABC) transporter
UC8_RS08555	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
UC8_RS08560	COG2815	serine threonine protein kinase
UC8_RS08560	COG0515	serine threonine protein kinase
UC8_RS08595	COG0515	serine threonine protein kinase
UC8_RS08595	COG2815	serine threonine protein kinase
UC8_RS08630	COG1459	type II secretion system
UC8_RS08655	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
UC8_RS08695	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
UC8_RS08700	COG0509	glycine decarboxylation via glycine cleavage system
UC8_RS08705	COG0635	Involved in the biosynthesis of porphyrin-containing compound
UC8_RS08715	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
UC8_RS08730	COG0445	tRNA wobble uridine modification
UC8_RS08745	COG1131	(ABC) transporter
UC8_RS08765	COG0516	GMP reductase activity
UC8_RS08765	COG0517	IMP dehydrogenase activity
UC8_RS08780	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
UC8_RS08785	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
UC8_RS08790	COG0515	serine threonine protein kinase
UC8_RS08845	COG1028	Short-chain dehydrogenase reductase Sdr
UC8_RS08850	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
UC8_RS08855	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
UC8_RS08885	COG2195	Cleaves the N-terminal amino acid of tripeptides
UC8_RS08890	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
UC8_RS08915	COG1028	Short-chain dehydrogenase reductase Sdr
UC8_RS08920	COG1881	PFAM PEBP family protein
UC8_RS08925	COG0823	Involved in the tonB-independent uptake of proteins
UC8_RS08925	COG1506	peptidase
UC8_RS08925	COG4946	Tricorn protease homolog
UC8_RS08975	COG0316	Belongs to the HesB IscA family
UC8_RS08990	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
UC8_RS09005	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
UC8_RS09020	COG1943	Transposase
UC8_RS09040	COG1069	ribulokinase activity
UC8_RS09045	COG1760	l-serine dehydratase
UC8_RS09060	COG1116	anion transmembrane transporter activity
UC8_RS09070	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
UC8_RS09075	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
UC8_RS09130	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
UC8_RS09210	COG0544	peptidyl-prolyl cis-trans isomerase activity
UC8_RS09220	COG1294	oxidase, subunit
UC8_RS09225	COG1271	oxidase subunit
UC8_RS09240	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
UC8_RS09240	COG0574	Belongs to the PEP-utilizing enzyme family
UC8_RS09250	COG0359	binds to the 23S rRNA
UC8_RS09255	COG0629	single-stranded DNA binding
UC8_RS09260	COG0360	Binds together with S18 to 16S ribosomal RNA
UC8_RS09265	COG0193	aminoacyl-tRNA hydrolase activity
UC8_RS09270	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
UC8_RS09310	COG1573	uracil-dna glycosylase
UC8_RS09315	COG0587	DNA-directed DNA polymerase activity
UC8_RS09335	COG3119	arylsulfatase activity
UC8_RS09370	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
UC8_RS09380	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
UC8_RS09385	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
UC8_RS09390	COG0163	prenyltransferase activity
UC8_RS09395	COG2226	methyltransferase
UC8_RS09415	COG5002	protein histidine kinase activity
UC8_RS09415	COG0784	Response regulator, receiver
UC8_RS09415	COG2205	protein histidine kinase activity
UC8_RS09430	COG1028	Short-chain dehydrogenase reductase Sdr
UC8_RS09430	COG0604	alcohol dehydrogenase
UC8_RS09430	COG3321	synthase
UC8_RS09510	COG0107	imidazoleglycerol-phosphate synthase activity
UC8_RS09560	COG1104	cysteine desulfurase activity
UC8_RS09565	COG0673	inositol 2-dehydrogenase activity
UC8_RS09590	COG0518	GMP synthase (glutamine-hydrolyzing) activity
UC8_RS09590	COG0519	Catalyzes the synthesis of GMP from XMP
UC8_RS09605	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
UC8_RS09630	COG4537	Required for transformation and DNA binding
UC8_RS09645	COG2815	serine threonine protein kinase
UC8_RS09645	COG0515	serine threonine protein kinase
UC8_RS09690	COG1774	PSP1 C-terminal conserved region
UC8_RS09700	COG2201	protein-glutamate methylesterase activity
UC8_RS09720	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
UC8_RS09725	COG0835	chemotaxis
UC8_RS09740	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
UC8_RS09800	COG0126	phosphoglycerate kinase activity
UC8_RS09805	COG1446	asparaginase
UC8_RS09875	COG0737	Belongs to the 5'-nucleotidase family
UC8_RS09880	COG0243	molybdopterin cofactor binding
UC8_RS09890	COG1940	carbohydrate kinase activity
UC8_RS09895	COG0481	GTPase activity
UC8_RS09940	COG1063	alcohol dehydrogenase
UC8_RS09975	COG3119	arylsulfatase activity
UC8_RS09980	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
UC8_RS09985	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
UC8_RS09995	COG0657	acetylesterase activity
UC8_RS10000	COG0515	serine threonine protein kinase
UC8_RS10005	COG0616	signal peptide processing
UC8_RS10010	COG1136	(ABC) transporter
UC8_RS10010	COG0577	efflux transmembrane transporter activity
UC8_RS10020	COG1136	(ABC) transporter
UC8_RS10025	COG3119	arylsulfatase activity
UC8_RS10025	COG3119	arylsulfatase activity
UC8_RS10050	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
UC8_RS10065	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
UC8_RS10080	COG1595	DNA-templated transcription, initiation
UC8_RS10100	COG0508	dehydrogenase complex catalyzes the overall conversion of
UC8_RS10120	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
UC8_RS10130	COG2815	serine threonine protein kinase
UC8_RS10130	COG0515	serine threonine protein kinase
UC8_RS10220	COG0277	FAD linked oxidase domain protein
UC8_RS10220	COG0247	lactate metabolic process
UC8_RS10230	COG1063	alcohol dehydrogenase
UC8_RS10240	COG0396	ATPase activity
UC8_RS10245	COG0719	Fe-S assembly protein
UC8_RS10250	COG0719	Fe-S assembly protein
UC8_RS10255	COG2151	metal-sulfur cluster biosynthetic enzyme
UC8_RS10280	COG1254	Belongs to the acylphosphatase family
UC8_RS10300	COG1040	competence protein
UC8_RS10320	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
UC8_RS10330	COG1233	COG1233 Phytoene dehydrogenase and related
UC8_RS10340	COG1216	Glycosyl transferase, family 2
UC8_RS10355	COG1131	(ABC) transporter
UC8_RS10480	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
UC8_RS10500	COG0861	Integral membrane protein TerC family
UC8_RS10520	COG4112	unkown
UC8_RS10525	COG1104	cysteine desulfurase activity
UC8_RS10530	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
UC8_RS10555	COG1129	ABC transporter
UC8_RS10560	COG1879	ABC-type sugar transport system periplasmic component
UC8_RS10840	COG3119	arylsulfatase activity
UC8_RS10865	COG0529	Catalyzes the synthesis of activated sulfate
UC8_RS10900	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
UC8_RS10900	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
UC8_RS10915	COG0673	inositol 2-dehydrogenase activity
UC8_RS10925	COG4796	Type ii and iii secretion system protein
UC8_RS10950	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
UC8_RS10975	COG0673	inositol 2-dehydrogenase activity
UC8_RS10995	COG0356	it plays a direct role in the translocation of protons across the membrane
UC8_RS11000	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
UC8_RS11005	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
UC8_RS11010	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
UC8_RS11015	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
UC8_RS11025	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
UC8_RS11030	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
UC8_RS11035	COG0355	proton-transporting ATP synthase activity, rotational mechanism
UC8_RS11045	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
UC8_RS11050	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
UC8_RS11055	COG0142	geranyltranstransferase activity
UC8_RS11070	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
UC8_RS11080	COG1063	alcohol dehydrogenase
UC8_RS11085	COG0156	8-amino-7-oxononanoate synthase activity
UC8_RS11090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
UC8_RS11090	COG2205	protein histidine kinase activity
UC8_RS11095	COG2205	protein histidine kinase activity
UC8_RS11095	COG3437	response regulator, receiver
UC8_RS11095	COG3850	Histidine kinase
UC8_RS11095	COG4999	Histidine kinase
UC8_RS11130	COG0456	acetyltransferase
UC8_RS11130	COG0454	-acetyltransferase
UC8_RS11160	COG0438	transferase activity, transferring glycosyl groups
UC8_RS11180	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
UC8_RS11235	COG1970	mechanosensitive ion channel activity
UC8_RS11250	COG1131	(ABC) transporter
UC8_RS11265	COG0824	Thioesterase
UC8_RS11270	COG0698	ribose 5-phosphate isomerase
UC8_RS11310	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
UC8_RS11315	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
UC8_RS11320	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
UC8_RS11325	COG1506	peptidase
UC8_RS11325	COG0823	Involved in the tonB-independent uptake of proteins
UC8_RS11350	COG0673	inositol 2-dehydrogenase activity
UC8_RS11355	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
UC8_RS11370	COG0113	porphobilinogen synthase activity
UC8_RS11385	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
UC8_RS11390	COG0187	DNA topoisomerase II activity
UC8_RS11395	COG4191	Histidine kinase
UC8_RS11450	COG1028	Short-chain dehydrogenase reductase Sdr
UC8_RS11455	COG0742	ribosomal rna small subunit methyltransferase
UC8_RS11460	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
UC8_RS11480	COG1381	Involved in DNA repair and RecF pathway recombination
UC8_RS11510	COG0602	queuosine metabolic process
UC8_RS11515	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
UC8_RS11530	COG0300	oxidoreductase activity
UC8_RS11535	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
UC8_RS11560	COG1242	4 iron, 4 sulfur cluster binding
UC8_RS11570	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
UC8_RS11590	COG1597	lipid kinase activity
UC8_RS11595	COG4251	negative regulation of phosphorylation
UC8_RS11600	COG2204	response regulator
UC8_RS11610	COG1475	DNA binding
UC8_RS11615	COG1192	Involved in chromosome partitioning
UC8_RS11625	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
UC8_RS11640	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
UC8_RS11650	COG0318	PFAM AMP-dependent synthetase and ligase
UC8_RS11675	COG1570	exodeoxyribonuclease VII activity
UC8_RS11690	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
UC8_RS11705	COG0457	Tetratricopeptide repeat
UC8_RS11705	COG0515	serine threonine protein kinase
UC8_RS11710	COG4935	Belongs to the peptidase S8 family
UC8_RS11710	COG2234	aminopeptidase activity
UC8_RS11715	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
UC8_RS11730	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
UC8_RS11740	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
UC8_RS11745	COG0799	negative regulation of ribosome biogenesis
UC8_RS11750	COG0018	arginyl-trna synthetase
UC8_RS11760	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
UC8_RS11880	COG0297	glycogen (starch) synthase activity
UC8_RS11985	COG2815	serine threonine protein kinase
UC8_RS11985	COG0515	serine threonine protein kinase
UC8_RS12175	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
UC8_RS12195	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
UC8_RS12205	COG0811	peptide transport
UC8_RS12210	COG0165	Argininosuccinate lyase
UC8_RS12215	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
UC8_RS12235	COG0488	(ABC) transporter
UC8_RS12245	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
UC8_RS12265	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
UC8_RS12275	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
UC8_RS12275	COG1918	ferrous iron import across plasma membrane
UC8_RS12285	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
UC8_RS12415	COG1477	protein flavinylation
UC8_RS12440	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
UC8_RS12450	COG2813	Specifically methylates the guanine in position
UC8_RS12500	COG2165	general secretion pathway protein
UC8_RS12505	COG1459	type II secretion system
UC8_RS12510	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
UC8_RS12520	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
UC8_RS12575	COG0457	Tetratricopeptide repeat
UC8_RS12575	COG0515	serine threonine protein kinase
UC8_RS12585	COG4251	negative regulation of phosphorylation
UC8_RS12600	COG3852	Histidine kinase
UC8_RS12605	COG1063	alcohol dehydrogenase
UC8_RS12625	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
UC8_RS12630	COG0305	Participates in initiation and elongation during chromosome replication
UC8_RS12655	COG0628	permease
UC8_RS12675	COG0516	GMP reductase activity
UC8_RS12680	COG0589	response to stress
UC8_RS12695	COG2197	response regulator
UC8_RS12730	COG3119	arylsulfatase activity
UC8_RS12735	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
UC8_RS12740	COG0220	tRNA (guanine-N7-)-methyltransferase activity
UC8_RS12745	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
UC8_RS12825	COG2373	Large extracellular alpha-helical protein
UC8_RS12845	COG1137	ATPase activity
UC8_RS12910	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
UC8_RS12945	COG1216	Glycosyl transferase, family 2
UC8_RS12990	COG0482	sulfurtransferase activity
UC8_RS12995	COG2379	hydroxypyruvate reductase
UC8_RS13020	COG4221	oxidoreductase activity
UC8_RS13025	COG0300	oxidoreductase activity
UC8_RS13040	COG0659	secondary active sulfate transmembrane transporter activity
UC8_RS13055	COG0521	Mo-molybdopterin cofactor biosynthetic process
UC8_RS13180	COG0514	ATP-dependent DNA helicase (RecQ)
UC8_RS13200	COG0604	alcohol dehydrogenase
UC8_RS13205	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
UC8_RS13220	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
UC8_RS13235	COG0596	Alpha beta hydrolase
UC8_RS13250	COG2154	pterin-4-alpha-carbinolamine dehydratase
UC8_RS13255	COG0077	Prephenate dehydratase
UC8_RS13255	COG1605	Chorismate mutase
UC8_RS13260	COG0443	Heat shock 70 kDa protein
UC8_RS13270	COG0542	response to heat
UC8_RS13280	COG2255	four-way junction helicase activity
UC8_RS13310	COG1183	phosphatidylcholine synthase activity
UC8_RS13315	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
UC8_RS13355	COG0714	Associated with various cellular activities
UC8_RS13365	COG3119	arylsulfatase activity
UC8_RS13385	COG0354	folic acid binding
UC8_RS13400	COG0702	epimerase
UC8_RS13410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
UC8_RS13420	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
UC8_RS13425	COG1309	transcriptional regulator
UC8_RS13430	COG1028	Short-chain dehydrogenase reductase Sdr
UC8_RS13435	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
UC8_RS13455	COG1845	cytochrome c oxidase, subunit III
UC8_RS13465	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
UC8_RS13495	COG0437	4 iron, 4 sulfur cluster binding
UC8_RS13515	COG2816	NAD+ diphosphatase activity
UC8_RS13520	COG0617	tRNA 3'-terminal CCA addition
UC8_RS13530	COG0493	'glutamate synthase
UC8_RS13535	COG0070	glutamate synthase
UC8_RS13535	COG0069	glutamate synthase activity
UC8_RS13535	COG0067	glutamate synthase
UC8_RS13540	COG0583	DNA-binding transcription factor activity
UC8_RS13550	COG0167	dihydroorotate dehydrogenase activity
UC8_RS13570	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
UC8_RS13640	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
UC8_RS13645	COG0072	phenylalanine-tRNA ligase activity
UC8_RS13650	COG0346	lactoylglutathione lyase activity
UC8_RS13655	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
UC8_RS13660	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
UC8_RS13665	COG0291	Belongs to the bacterial ribosomal protein bL35 family
UC8_RS13670	COG0284	orotidine-5'-phosphate decarboxylase activity
UC8_RS13685	COG3237	CsbD-like
UC8_RS13720	COG0321	lipoyl(octanoyl) transferase activity
UC8_RS13720	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
UC8_RS13835	COG3119	arylsulfatase activity
UC8_RS13845	COG3119	arylsulfatase activity
UC8_RS13870	COG0653	protein targeting
UC8_RS13905	COG0384	phenazine biosynthesis protein PhzF
UC8_RS13940	COG3321	synthase
UC8_RS13940	COG0604	alcohol dehydrogenase
UC8_RS13945	COG1733	regulation of RNA biosynthetic process
UC8_RS13955	COG0702	epimerase
UC8_RS13960	COG2015	COG2015, Alkyl sulfatase and related hydrolases
UC8_RS13965	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
UC8_RS13975	COG2015	COG2015, Alkyl sulfatase and related hydrolases
UC8_RS14010	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
UC8_RS14040	COG0515	serine threonine protein kinase
UC8_RS14040	COG2815	serine threonine protein kinase
UC8_RS14060	COG0798	PFAM Bile acid sodium symporter
UC8_RS14095	COG2165	general secretion pathway protein
UC8_RS14110	COG0714	Associated with various cellular activities
UC8_RS14195	COG1216	Glycosyl transferase, family 2
UC8_RS14215	COG4964	Belongs to the GSP D family
UC8_RS14245	COG0523	cobalamin synthesis protein
UC8_RS14285	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
UC8_RS14290	COG1335	isochorismatase
UC8_RS14305	COG4589	Belongs to the CDS family
UC8_RS14315	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
UC8_RS14330	COG3604	Transcriptional regulator
UC8_RS14340	COG0300	oxidoreductase activity
UC8_RS14375	COG3119	arylsulfatase activity
UC8_RS14380	COG3795	YCII-related domain
UC8_RS14410	COG4941	Belongs to the sigma-70 factor family
UC8_RS14445	COG0515	serine threonine protein kinase
UC8_RS14470	COG2815	serine threonine protein kinase
UC8_RS14470	COG0515	serine threonine protein kinase
UC8_RS14485	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
UC8_RS14490	COG0583	DNA-binding transcription factor activity
UC8_RS14500	COG2824	Alkylphosphonate utilization operon protein PhnA
UC8_RS14515	COG0515	serine threonine protein kinase
UC8_RS14515	COG2815	serine threonine protein kinase
UC8_RS14520	COG1262	PFAM Formylglycine-generating sulfatase enzyme
UC8_RS14525	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
UC8_RS14530	COG2130	NADP-dependent
UC8_RS14575	COG2198	Histidine kinase
UC8_RS14575	COG0784	Response regulator, receiver
UC8_RS14575	COG5002	protein histidine kinase activity
UC8_RS14580	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
UC8_RS14585	COG0401	homolog of Blt101
UC8_RS14590	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
UC8_RS14605	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
UC8_RS14610	COG0753	catalase activity
UC8_RS14620	COG0590	tRNA wobble adenosine to inosine editing
UC8_RS14630	COG1201	RNA secondary structure unwinding
UC8_RS14635	COG1793	dna ligase
UC8_RS14645	COG1573	uracil-dna glycosylase
UC8_RS14655	COG0019	diaminopimelate decarboxylase activity
UC8_RS14665	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
UC8_RS14670	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
UC8_RS14685	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
UC8_RS14690	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
UC8_RS14700	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
UC8_RS14720	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
UC8_RS14725	COG0415	Belongs to the DNA photolyase family
UC8_RS14735	COG2226	methyltransferase
UC8_RS14740	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
UC8_RS14745	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
UC8_RS14785	COG1846	Transcriptional regulator
UC8_RS14820	COG0714	Associated with various cellular activities
UC8_RS14830	COG0129	dihydroxy-acid dehydratase activity
UC8_RS14835	COG0793	Belongs to the peptidase S41A family
UC8_RS14840	COG0693	protein deglycase activity
UC8_RS14845	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
UC8_RS14860	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
UC8_RS14860	COG1017	nitric oxide dioxygenase activity
UC8_RS14870	COG0515	serine threonine protein kinase
UC8_RS14870	COG2815	serine threonine protein kinase
UC8_RS14875	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
UC8_RS14880	COG3119	arylsulfatase activity
UC8_RS14885	COG3706	GGDEF domain
UC8_RS14895	COG1733	regulation of RNA biosynthetic process
UC8_RS14915	COG0628	permease
UC8_RS15010	COG3540	Alkaline phosphatase
UC8_RS15020	COG0246	Mannitol dehydrogenase
UC8_RS15040	COG2815	serine threonine protein kinase
UC8_RS15040	COG0515	serine threonine protein kinase
UC8_RS15085	COG3119	arylsulfatase activity
UC8_RS15100	COG1262	PFAM Formylglycine-generating sulfatase enzyme
UC8_RS15120	COG0643	Histidine kinase
UC8_RS15120	COG2198	Histidine kinase
UC8_RS15140	COG0745	RESPONSE REGULATOR receiver
UC8_RS15185	COG1506	peptidase
UC8_RS15185	COG0823	Involved in the tonB-independent uptake of proteins
UC8_RS15215	COG1160	GTP binding
UC8_RS15230	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
UC8_RS15240	COG1966	Carbon starvation protein
UC8_RS15265	COG0328	RNA-DNA hybrid ribonuclease activity
UC8_RS15270	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
UC8_RS15285	COG0750	zinc metalloprotease
UC8_RS15295	COG0673	inositol 2-dehydrogenase activity
UC8_RS15300	COG3253	May function as heme-dependent peroxidase
UC8_RS15310	COG0297	glycogen (starch) synthase activity
UC8_RS15325	COG0673	inositol 2-dehydrogenase activity
UC8_RS15365	COG2382	esterase
UC8_RS15365	COG3693	PFAM glycoside hydrolase, family 10
UC8_RS15370	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
UC8_RS15370	COG1796	DNA polymerase
UC8_RS15400	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
UC8_RS15430	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
UC8_RS15440	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
UC8_RS15445	COG0242	peptide deformylase activity
UC8_RS15465	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
UC8_RS15480	COG2816	NAD+ diphosphatase activity
UC8_RS15505	COG0515	serine threonine protein kinase
UC8_RS15505	COG2815	serine threonine protein kinase
UC8_RS15535	COG1063	alcohol dehydrogenase
UC8_RS15555	COG1418	mRNA catabolic process
UC8_RS15565	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
UC8_RS15570	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
UC8_RS15580	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
UC8_RS15610	COG0481	GTPase activity
UC8_RS15635	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
UC8_RS15640	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
UC8_RS15650	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
UC8_RS15670	COG0673	inositol 2-dehydrogenase activity
UC8_RS15695	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
UC8_RS15710	COG4555	ABC transporter
UC8_RS15715	COG1668	transmembrane transport
UC8_RS15720	COG2501	S4 domain
UC8_RS15730	COG0052	Belongs to the universal ribosomal protein uS2 family
UC8_RS15735	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
UC8_RS15760	COG2706	6-phosphogluconolactonase activity
UC8_RS15775	COG1672	PFAM Archaeal ATPase
UC8_RS15775	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
UC8_RS15780	COG2010	Cytochrome c
UC8_RS15790	COG1136	(ABC) transporter
UC8_RS15815	COG1028	Short-chain dehydrogenase reductase Sdr
UC8_RS15835	COG1278	Cold shock
UC8_RS15860	COG3119	arylsulfatase activity
UC8_RS15870	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
UC8_RS15880	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
UC8_RS15885	COG0315	cyclic pyranopterin monophosphate synthase activity
UC8_RS15895	COG0736	holo-[acyl-carrier-protein] synthase activity
UC8_RS15940	COG2738	Putative neutral zinc metallopeptidase
UC8_RS15950	COG0635	Involved in the biosynthesis of porphyrin-containing compound
UC8_RS15970	COG0668	transmembrane transport
UC8_RS15980	COG1217	gtp-binding protein TYPA
UC8_RS15990	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
UC8_RS15995	COG1805	sodium ion transport
UC8_RS16000	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
UC8_RS16005	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
UC8_RS16010	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
UC8_RS16030	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
UC8_RS16035	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
UC8_RS16040	COG0628	permease
UC8_RS16045	COG1733	regulation of RNA biosynthetic process
UC8_RS16080	COG3385	transposase activity
UC8_RS16145	COG1028	Short-chain dehydrogenase reductase Sdr
UC8_RS16150	COG3387	PFAM Glycoside hydrolase 15-related
UC8_RS16185	COG1937	Protein conserved in bacteria
UC8_RS16220	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
UC8_RS16265	COG1136	(ABC) transporter
UC8_RS16270	COG0577	efflux transmembrane transporter activity
UC8_RS16270	COG1136	(ABC) transporter
UC8_RS16370	COG2124	cytochrome p450
UC8_RS16375	COG3118	belongs to the thioredoxin family
UC8_RS16415	COG2814	Major facilitator Superfamily
UC8_RS16450	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
UC8_RS16520	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
UC8_RS16655	COG2304	oxidoreductase activity
UC8_RS16660	COG1595	DNA-templated transcription, initiation
UC8_RS16680	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
UC8_RS16700	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
UC8_RS16710	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
UC8_RS16715	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
UC8_RS16715	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
UC8_RS16735	COG2304	oxidoreductase activity
UC8_RS16740	COG0322	excinuclease ABC activity
UC8_RS16745	COG1234	tRNA 3'-trailer cleavage
UC8_RS16750	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
UC8_RS16765	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
UC8_RS16770	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
UC8_RS16790	COG0363	glucosamine-6-phosphate deaminase activity
UC8_RS16795	COG0705	Rhomboid family
UC8_RS16800	COG0534	Mate efflux family protein
UC8_RS16810	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
UC8_RS16820	COG1754	DNA topoisomerase type I activity
UC8_RS16820	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
UC8_RS16845	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
UC8_RS16855	COG0706	membrane insertase activity
UC8_RS16855	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
UC8_RS16860	COG0828	Belongs to the bacterial ribosomal protein bS21 family
UC8_RS16930	COG1162	GTPase activity
UC8_RS16935	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
UC8_RS16940	COG0514	ATP-dependent DNA helicase (RecQ)
UC8_RS16945	COG2045	Belongs to the ComB family
UC8_RS16955	COG3118	belongs to the thioredoxin family
UC8_RS16970	COG0714	Associated with various cellular activities
UC8_RS17015	COG1530	ribonuclease E activity
UC8_RS17025	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
UC8_RS17035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
UC8_RS17045	COG0515	serine threonine protein kinase
UC8_RS17090	COG0714	Associated with various cellular activities
UC8_RS17120	COG2183	response to ionizing radiation
UC8_RS17120	COG0539	negative regulation of cytoplasmic translation
UC8_RS17125	COG0698	ribose 5-phosphate isomerase
UC8_RS17130	COG0515	serine threonine protein kinase
UC8_RS17130	COG1262	PFAM Formylglycine-generating sulfatase enzyme
UC8_RS17135	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
UC8_RS17150	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
UC8_RS17160	COG0420	3'-5' exonuclease activity
UC8_RS17190	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
UC8_RS17200	COG1556	Lactate utilization protein
UC8_RS17205	COG1139	Iron-sulfur cluster binding protein
UC8_RS17210	COG0247	lactate metabolic process
UC8_RS17215	COG2885	chlorophyll binding
UC8_RS17240	COG3228	Belongs to the MtfA family
UC8_RS17250	COG0515	serine threonine protein kinase
UC8_RS17260	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
UC8_RS17265	COG3831	ATPase activity
UC8_RS17270	COG0714	Associated with various cellular activities
UC8_RS17280	COG3552	Protein containing von Willebrand factor type A (VWA) domain
UC8_RS17310	COG0705	Rhomboid family
UC8_RS17310	COG0457	Tetratricopeptide repeat
UC8_RS17315	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
UC8_RS17320	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
UC8_RS17325	COG3119	arylsulfatase activity
UC8_RS17340	COG3119	arylsulfatase activity
UC8_RS17345	COG3119	arylsulfatase activity
UC8_RS17350	COG3119	arylsulfatase activity
UC8_RS17365	COG1012	belongs to the aldehyde dehydrogenase family
UC8_RS17390	COG1131	(ABC) transporter
UC8_RS17425	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
UC8_RS17430	COG1671	Belongs to the UPF0178 family
UC8_RS17500	COG2204	response regulator
UC8_RS17515	COG1733	regulation of RNA biosynthetic process
UC8_RS17545	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
UC8_RS17555	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
UC8_RS17560	COG3119	arylsulfatase activity
UC8_RS17655	COG2165	general secretion pathway protein
UC8_RS17680	COG3852	Histidine kinase
UC8_RS17685	COG0750	zinc metalloprotease
UC8_RS17695	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
UC8_RS17700	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
UC8_RS17705	COG0673	inositol 2-dehydrogenase activity
UC8_RS17725	COG4191	Histidine kinase
UC8_RS17730	COG0471	metal ion transport
UC8_RS17760	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
UC8_RS17780	COG1606	tRNA processing
UC8_RS17785	COG0515	serine threonine protein kinase
UC8_RS17800	COG0114	fumarate hydratase activity
UC8_RS17815	COG0588	phosphoglycerate mutase activity
UC8_RS17820	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
UC8_RS17830	COG1131	(ABC) transporter
UC8_RS17840	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
UC8_RS17845	COG0527	aspartate kinase activity
UC8_RS17850	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
UC8_RS17870	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
UC8_RS17920	COG1959	2 iron, 2 sulfur cluster binding
UC8_RS17945	COG0386	Belongs to the glutathione peroxidase family
UC8_RS17950	COG3385	transposase activity
UC8_RS17980	COG0628	permease
UC8_RS18030	COG0105	UTP biosynthetic process
UC8_RS18045	COG0363	glucosamine-6-phosphate deaminase activity
UC8_RS18050	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
UC8_RS18060	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
UC8_RS18065	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
UC8_RS18070	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
UC8_RS18075	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
UC8_RS18090	COG0512	Glutamine amidotransferase of anthranilate synthase
UC8_RS18100	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
UC8_RS18110	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
UC8_RS18115	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
UC8_RS18135	COG3119	arylsulfatase activity
UC8_RS18150	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
UC8_RS18155	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
UC8_RS18160	COG0131	Imidazoleglycerol-phosphate dehydratase
UC8_RS18170	COG4864	UPF0365 protein
UC8_RS18175	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
UC8_RS18195	COG3264	Mechanosensitive ion channel
UC8_RS18195	COG1511	domain protein
UC8_RS18200	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
UC8_RS18210	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
UC8_RS18220	COG0673	inositol 2-dehydrogenase activity
UC8_RS18230	COG0148	phosphopyruvate hydratase activity
UC8_RS18240	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
UC8_RS18255	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
UC8_RS18265	COG0517	IMP dehydrogenase activity
UC8_RS18265	COG0516	GMP reductase activity
UC8_RS18275	COG3119	arylsulfatase activity
UC8_RS18290	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
UC8_RS18310	COG1070	Carbohydrate kinase
UC8_RS18320	COG0673	inositol 2-dehydrogenase activity
UC8_RS18355	COG2815	serine threonine protein kinase
UC8_RS18355	COG0515	serine threonine protein kinase
UC8_RS18375	COG5002	protein histidine kinase activity
UC8_RS18385	COG0596	Alpha beta hydrolase
UC8_RS18390	COG0288	reversible hydration of carbon dioxide
UC8_RS18400	COG1741	Belongs to the pirin family
UC8_RS18420	COG3119	arylsulfatase activity
UC8_RS18435	COG0515	serine threonine protein kinase
UC8_RS18435	COG2815	serine threonine protein kinase
UC8_RS18445	COG2202	Pas domain
UC8_RS18445	COG2205	protein histidine kinase activity
UC8_RS18450	COG3119	arylsulfatase activity
UC8_RS18485	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
UC8_RS18525	COG1131	(ABC) transporter
UC8_RS18530	COG1725	Transcriptional regulator
UC8_RS18550	COG3119	arylsulfatase activity
UC8_RS18575	COG1519	Transferase
UC8_RS18580	COG0653	protein targeting
UC8_RS18590	COG2815	serine threonine protein kinase
UC8_RS18590	COG0515	serine threonine protein kinase
UC8_RS18605	COG0667	Aldo Keto reductase
UC8_RS18610	COG1063	alcohol dehydrogenase
UC8_RS18620	COG1028	Short-chain dehydrogenase reductase Sdr
UC8_RS18625	COG1082	Xylose isomerase domain protein TIM barrel
UC8_RS18635	COG0714	Associated with various cellular activities
UC8_RS18645	COG0793	Belongs to the peptidase S41A family
UC8_RS18650	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
UC8_RS18655	COG0357	Ribosomal RNA small subunit methyltransferase G
UC8_RS18660	COG0175	sulfate reduction
UC8_RS18665	COG0529	Catalyzes the synthesis of activated sulfate
UC8_RS18665	COG2895	sulfate adenylyltransferase (ATP) activity
UC8_RS18680	COG1136	(ABC) transporter
UC8_RS18685	COG0577	efflux transmembrane transporter activity
UC8_RS18690	COG0584	glycerophosphoryl diester phosphodiesterase
UC8_RS18705	COG0071	Belongs to the small heat shock protein (HSP20) family
UC8_RS18710	COG1295	ribonuclease BN
UC8_RS18720	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
UC8_RS18725	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
UC8_RS18730	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
UC8_RS18740	COG0575	Belongs to the CDS family
UC8_RS18745	COG0084	hydrolase, TatD family'
UC8_RS18765	COG4864	UPF0365 protein
UC8_RS18790	COG1196	nuclear chromosome segregation
UC8_RS18800	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
UC8_RS18805	COG0257	Belongs to the bacterial ribosomal protein bL36 family
UC8_RS18830	COG1070	Carbohydrate kinase
UC8_RS18865	COG1012	belongs to the aldehyde dehydrogenase family
UC8_RS18885	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
UC8_RS19025	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
UC8_RS19030	COG0028	Belongs to the TPP enzyme family
UC8_RS19050	COG2197	response regulator
UC8_RS19065	COG3344	reverse transcriptase
UC8_RS19125	COG3693	PFAM glycoside hydrolase, family 10
UC8_RS19125	COG3509	depolymerase
UC8_RS19130	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
UC8_RS19155	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
UC8_RS19165	COG1937	Protein conserved in bacteria
UC8_RS19180	COG2217	Heavy metal translocating P-type atpase
UC8_RS19190	COG3119	arylsulfatase activity
UC8_RS19215	COG0339	signal peptide processing
UC8_RS19230	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
UC8_RS19245	COG1192	Involved in chromosome partitioning
UC8_RS19290	COG0318	PFAM AMP-dependent synthetase and ligase
UC8_RS19300	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
UC8_RS19310	COG0577	efflux transmembrane transporter activity
UC8_RS19310	COG1136	(ABC) transporter
UC8_RS19315	COG2198	Histidine kinase
UC8_RS19315	COG0643	Histidine kinase
UC8_RS19320	COG2205	protein histidine kinase activity
UC8_RS19320	COG2198	Histidine kinase
UC8_RS19320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
UC8_RS19320	COG0784	Response regulator, receiver
UC8_RS19325	COG4251	negative regulation of phosphorylation
UC8_RS19330	COG4251	negative regulation of phosphorylation
UC8_RS19335	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
UC8_RS19345	COG3237	CsbD-like
UC8_RS19360	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
UC8_RS19370	COG1335	isochorismatase
UC8_RS19385	COG0500	methyltransferase
UC8_RS19405	COG0726	polysaccharide deacetylase
UC8_RS19450	COG0438	transferase activity, transferring glycosyl groups
UC8_RS19460	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
UC8_RS19490	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
UC8_RS19495	COG0484	heat shock protein binding
UC8_RS19500	COG0459	protein refolding
UC8_RS19505	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
UC8_RS19510	COG0459	protein refolding
UC8_RS19530	COG1752	Esterase of the alpha-beta hydrolase superfamily
UC8_RS19535	COG1960	acyl-CoA dehydrogenase activity
UC8_RS19540	COG1024	Enoyl-CoA hydratase
UC8_RS19540	COG1250	3-hydroxyacyl-CoA dehydrogenase
UC8_RS19545	COG0183	Belongs to the thiolase family
UC8_RS19550	COG0318	PFAM AMP-dependent synthetase and ligase
UC8_RS19595	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
UC8_RS19605	COG0495	leucyl-tRNA aminoacylation
UC8_RS19610	COG0024	Methionine aminopeptidase
UC8_RS19615	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
UC8_RS19620	COG0525	valine-tRNA ligase activity
UC8_RS19655	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
UC8_RS19660	COG1509	lysine 2,3-aminomutase activity
UC8_RS19680	COG0438	transferase activity, transferring glycosyl groups
UC8_RS19695	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
UC8_RS19700	COG0181	hydroxymethylbilane synthase activity
UC8_RS19740	COG0363	glucosamine-6-phosphate deaminase activity
UC8_RS19745	COG0671	phosphoesterase, PA-phosphatase related
UC8_RS19765	COG1695	Transcriptional regulator
UC8_RS19770	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
UC8_RS19775	COG3852	Histidine kinase
UC8_RS19780	COG2204	response regulator
UC8_RS19785	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
UC8_RS19790	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
UC8_RS19815	COG2943	transferase activity, transferring hexosyl groups
UC8_RS19820	COG0776	regulation of translation
UC8_RS19835	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
UC8_RS19900	COG2010	Cytochrome c
UC8_RS19960	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
UC8_RS19975	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
UC8_RS19975	COG0515	serine threonine protein kinase
UC8_RS19985	COG0463	Glycosyl transferase, family 2
UC8_RS19995	COG0457	Tetratricopeptide repeat
UC8_RS19995	COG0515	serine threonine protein kinase
UC8_RS20000	COG3237	CsbD-like
UC8_RS20020	COG0189	ligase activity
UC8_RS20025	COG3237	CsbD-like
UC8_RS20030	COG0628	permease
UC8_RS20035	COG2205	protein histidine kinase activity
UC8_RS20035	COG0784	Response regulator, receiver
UC8_RS20040	COG0784	Response regulator, receiver
UC8_RS20040	COG2205	protein histidine kinase activity
UC8_RS20055	COG2226	methyltransferase
UC8_RS20085	COG0612	Peptidase, M16
UC8_RS20090	COG0322	excinuclease ABC activity
UC8_RS20105	COG3618	amidohydrolase
UC8_RS20120	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
UC8_RS20130	COG0714	Associated with various cellular activities
UC8_RS20320	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
UC8_RS20365	COG1012	belongs to the aldehyde dehydrogenase family
UC8_RS20370	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
UC8_RS20380	COG4122	O-methyltransferase activity
UC8_RS20385	COG0386	Belongs to the glutathione peroxidase family
UC8_RS20395	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
UC8_RS20420	COG1252	NADH dehydrogenase
UC8_RS20430	COG0612	Peptidase, M16
UC8_RS20445	COG2610	gluconate transmembrane transporter activity
UC8_RS20450	COG0861	Integral membrane protein TerC family
UC8_RS20515	COG2223	nitrite transmembrane transporter activity
UC8_RS20540	COG2319	Wd-40 repeat
UC8_RS20580	COG0604	alcohol dehydrogenase
UC8_RS20580	COG1028	Short-chain dehydrogenase reductase Sdr
UC8_RS20580	COG3321	synthase
UC8_RS20590	COG0564	pseudouridine synthase activity
UC8_RS20600	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
UC8_RS20605	COG0673	inositol 2-dehydrogenase activity
UC8_RS20645	COG3119	arylsulfatase activity
UC8_RS20650	COG2226	methyltransferase
UC8_RS20660	COG0598	Magnesium transport protein CorA
UC8_RS20675	COG2855	membrane
UC8_RS20685	COG0714	Associated with various cellular activities
UC8_RS20700	COG2304	oxidoreductase activity
UC8_RS20705	COG2304	oxidoreductase activity
UC8_RS20725	COG0424	maF-like protein
UC8_RS20735	COG0203	ribosomal protein L17
UC8_RS20740	COG0202	RNA polymerase activity
UC8_RS20745	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
UC8_RS20750	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
UC8_RS20765	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
UC8_RS20770	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
UC8_RS20785	COG0740	serine-type endopeptidase activity
UC8_RS20790	COG0740	serine-type endopeptidase activity
UC8_RS20795	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
UC8_RS20810	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
UC8_RS20820	COG2088	sporulation resulting in formation of a cellular spore
UC8_RS20825	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
UC8_RS20830	COG4786	Flagellar basal body rod
UC8_RS20835	COG4786	Flagellar basal body rod
UC8_RS20845	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
UC8_RS20850	COG1706	bacterial-type flagellum-dependent cell motility
UC8_RS20865	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
UC8_RS20875	COG1361	Conserved repeat domain
UC8_RS20890	COG0589	response to stress
UC8_RS20920	COG0513	Belongs to the DEAD box helicase family
UC8_RS20925	COG3119	arylsulfatase activity
UC8_RS20940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
UC8_RS20950	COG1253	flavin adenine dinucleotide binding
UC8_RS20955	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
UC8_RS20960	COG1480	7TM receptor with intracellular HD hydrolase
UC8_RS20965	COG1702	phosphate starvation-inducible protein PhoH
UC8_RS20970	COG0575	Belongs to the CDS family
UC8_RS20975	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
UC8_RS20995	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
UC8_RS21000	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
UC8_RS21010	COG0159	tryptophan synthase activity
UC8_RS21025	COG0287	Prephenate dehydrogenase
UC8_RS21030	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
UC8_RS21035	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
UC8_RS21040	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
UC8_RS21055	COG0459	protein refolding
UC8_RS21060	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
UC8_RS21080	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
UC8_RS21095	COG0142	geranyltranstransferase activity
UC8_RS21105	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
UC8_RS21125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
UC8_RS21140	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
UC8_RS21225	COG1404	Belongs to the peptidase S8 family
UC8_RS21225	COG4412	M6 family metalloprotease domain protein
UC8_RS21240	COG2081	HI0933 family
UC8_RS21265	COG1355	regulation of microtubule-based process
UC8_RS21270	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
UC8_RS21275	COG0822	iron-sulfur transferase activity
UC8_RS21310	COG0714	Associated with various cellular activities
UC8_RS21330	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
UC8_RS21340	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
UC8_RS21350	COG2205	protein histidine kinase activity
UC8_RS21350	COG5002	protein histidine kinase activity
UC8_RS21350	COG0784	Response regulator, receiver
UC8_RS21420	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
UC8_RS21440	COG1546	Belongs to the CinA family
UC8_RS21440	COG1058	Belongs to the CinA family
UC8_RS21445	COG0776	regulation of translation
UC8_RS21485	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
UC8_RS21535	COG1725	Transcriptional regulator
UC8_RS21540	COG1131	(ABC) transporter
UC8_RS21575	COG3119	arylsulfatase activity
UC8_RS21600	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
UC8_RS21635	COG0450	alkyl hydroperoxide reductase
UC8_RS21655	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
UC8_RS21675	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
UC8_RS21710	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
UC8_RS21745	COG1643	Atp-dependent helicase
UC8_RS21755	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
UC8_RS21760	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
UC8_RS21770	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
UC8_RS21775	COG1214	PFAM Peptidase M22, glycoprotease
UC8_RS21795	COG1082	Xylose isomerase domain protein TIM barrel
UC8_RS21815	COG2326	polyphosphate kinase activity
UC8_RS21820	COG0667	Aldo Keto reductase
UC8_RS21830	COG0343	queuine tRNA-ribosyltransferase activity
UC8_RS21835	COG0202	RNA polymerase activity
UC8_RS21855	COG2936	dipeptidyl-peptidase activity
UC8_RS21860	COG0308	aminopeptidase N
UC8_RS21865	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
UC8_RS21870	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
UC8_RS21885	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
UC8_RS21890	COG0017	Asparaginyl-tRNA synthetase
UC8_RS21905	COG0180	Tryptophanyl-tRNA synthetase
UC8_RS21940	COG0505	Belongs to the CarA family
UC8_RS21945	COG4968	Prepilin-type N-terminal cleavage methylation domain
UC8_RS21965	COG0107	imidazoleglycerol-phosphate synthase activity
UC8_RS21970	COG3001	Fructosamine kinase
UC8_RS21980	COG0673	inositol 2-dehydrogenase activity
UC8_RS21985	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
UC8_RS21990	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
UC8_RS22020	COG1678	Uncharacterized ACR, COG1678
UC8_RS22025	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
UC8_RS22035	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
UC8_RS22080	COG1166	arginine decarboxylase activity
UC8_RS22095	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
UC8_RS22125	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
UC8_RS22135	COG0745	RESPONSE REGULATOR receiver
UC8_RS22140	COG0556	nucleotide-excision repair
UC8_RS22160	COG4974	Belongs to the 'phage' integrase family
UC8_RS22165	COG0366	Alpha amylase catalytic
UC8_RS22170	COG1215	transferase activity, transferring glycosyl groups
UC8_RS22180	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
UC8_RS22185	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
UC8_RS22195	COG1028	Short-chain dehydrogenase reductase Sdr
UC8_RS22225	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
UC8_RS22235	COG1408	metallophosphoesterase
UC8_RS22250	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
UC8_RS22260	COG0573	inorganic phosphate transmembrane transporter activity
UC8_RS22265	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
UC8_RS22270	COG5002	protein histidine kinase activity
UC8_RS22340	COG0438	transferase activity, transferring glycosyl groups
UC8_RS22380	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
UC8_RS22380	COG0517	IMP dehydrogenase activity
UC8_RS22420	COG0438	transferase activity, transferring glycosyl groups
UC8_RS22435	COG1216	Glycosyl transferase, family 2
UC8_RS22440	COG1215	transferase activity, transferring glycosyl groups
UC8_RS22455	COG0438	transferase activity, transferring glycosyl groups
UC8_RS22465	COG0438	transferase activity, transferring glycosyl groups
UC8_RS22480	COG0275	rRNA processing
UC8_RS22490	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
UC8_RS22515	COG0438	transferase activity, transferring glycosyl groups
UC8_RS22550	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
UC8_RS22645	COG0045	succinate-CoA ligase (ADP-forming) activity
UC8_RS22650	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
UC8_RS22655	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
UC8_RS22660	COG3344	reverse transcriptase
UC8_RS22665	COG0157	Belongs to the NadC ModD family
UC8_RS22700	COG2255	four-way junction helicase activity
UC8_RS22710	COG2962	Rard protein
UC8_RS22715	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
UC8_RS22750	COG0642	Histidine kinase
UC8_RS22760	COG1129	ABC transporter
UC8_RS22765	COG1172	Belongs to the binding-protein-dependent transport system permease family
UC8_RS22770	COG0513	Belongs to the DEAD box helicase family
UC8_RS22775	COG0667	Aldo Keto reductase
UC8_RS22805	COG0673	inositol 2-dehydrogenase activity
UC8_RS22840	COG1024	Enoyl-CoA hydratase
UC8_RS22840	COG1250	3-hydroxyacyl-CoA dehydrogenase
UC8_RS22860	COG0515	serine threonine protein kinase
UC8_RS22865	COG0222	ribosome binding
UC8_RS22940	COG0612	Peptidase, M16
UC8_RS23020	COG2204	response regulator
UC8_RS23050	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
UC8_RS23060	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
UC8_RS23065	COG0049	tRNA binding
UC8_RS23090	COG0714	Associated with various cellular activities
UC8_RS23115	COG0537	adenosine 5'-monophosphoramidase activity
UC8_RS23170	COG1013	pyruvate-flavodoxin oxidoreductase activity
UC8_RS23175	COG0674	pyruvate-flavodoxin oxidoreductase activity
UC8_RS23175	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
UC8_RS23180	COG2308	Evidence 4 Homologs of previously reported genes of
UC8_RS23195	COG2308	Evidence 4 Homologs of previously reported genes of
UC8_RS23200	COG1305	Transglutaminase-like
UC8_RS23205	COG0515	serine threonine protein kinase
UC8_RS23205	COG2815	serine threonine protein kinase
UC8_RS23210	COG0515	serine threonine protein kinase
UC8_RS23210	COG2815	serine threonine protein kinase
UC8_RS23215	COG0515	serine threonine protein kinase
UC8_RS23215	COG2815	serine threonine protein kinase
UC8_RS23225	COG1131	(ABC) transporter
UC8_RS23235	COG5002	protein histidine kinase activity
UC8_RS23240	COG0745	RESPONSE REGULATOR receiver
UC8_RS23245	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
UC8_RS23250	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
UC8_RS23255	COG0501	Belongs to the peptidase M48B family
UC8_RS23260	COG4555	ABC transporter
UC8_RS23275	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
UC8_RS23280	COG4980	gas vesicle protein
UC8_RS23280	COG1674	ftsk spoiiie
UC8_RS23290	COG0515	serine threonine protein kinase
UC8_RS23290	COG2815	serine threonine protein kinase
UC8_RS23305	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
UC8_RS23310	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
UC8_RS23315	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
UC8_RS23320	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
UC8_RS23330	COG0140	phosphoribosyl-ATP diphosphatase activity
UC8_RS23335	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
UC8_RS23345	COG0024	Methionine aminopeptidase
UC8_RS23370	COG0058	SHG alpha-glucan phosphorylase activity
UC8_RS23390	COG1595	DNA-templated transcription, initiation
UC8_RS23455	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
UC8_RS23460	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
UC8_RS23465	COG0211	Belongs to the bacterial ribosomal protein bL27 family
UC8_RS23510	COG0515	serine threonine protein kinase
UC8_RS23510	COG2815	serine threonine protein kinase
UC8_RS23525	COG1595	DNA-templated transcription, initiation
UC8_RS23565	COG1677	Flagellar hook-basal body complex protein FliE
UC8_RS23590	COG1157	protein secretion by the type III secretion system
UC8_RS23620	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
UC8_RS23625	COG1858	cytochrome C peroxidase
UC8_RS23645	COG3385	transposase activity
UC8_RS23655	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
UC8_RS23665	COG3119	arylsulfatase activity
UC8_RS23675	COG2815	serine threonine protein kinase
UC8_RS23675	COG0515	serine threonine protein kinase
UC8_RS23690	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
UC8_RS23705	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
UC8_RS23720	COG2706	6-phosphogluconolactonase activity
UC8_RS23730	COG0202	RNA polymerase activity
UC8_RS23760	COG4585	Histidine kinase
UC8_RS23785	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
UC8_RS23790	COG4974	Belongs to the 'phage' integrase family
UC8_RS23795	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
UC8_RS23805	COG0477	Major facilitator Superfamily
UC8_RS23810	COG2204	response regulator
UC8_RS23830	COG1132	(ABC) transporter
UC8_RS23840	COG0564	pseudouridine synthase activity
UC8_RS23855	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
UC8_RS23865	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
UC8_RS23880	COG0811	peptide transport
UC8_RS23905	COG0039	L-malate dehydrogenase activity
UC8_RS23915	COG0745	RESPONSE REGULATOR receiver
UC8_RS23920	COG2363	Small membrane protein
UC8_RS23925	COG0540	Belongs to the ATCase OTCase family
UC8_RS23930	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
UC8_RS23945	COG0667	Aldo Keto reductase
UC8_RS23965	COG0673	inositol 2-dehydrogenase activity
UC8_RS23970	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
UC8_RS23985	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
UC8_RS23990	COG0228	four-way junction DNA binding
UC8_RS23995	COG0336	Belongs to the RNA methyltransferase TrmD family
UC8_RS24000	COG0335	large ribosomal subunit rRNA binding
UC8_RS24005	COG0792	nuclease activity
UC8_RS24010	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
UC8_RS24030	COG0436	Aminotransferase
UC8_RS24045	COG2133	pyrroloquinoline quinone binding
UC8_RS24075	COG4555	ABC transporter
UC8_RS24080	COG0688	phosphatidylethanolamine metabolic process
UC8_RS24085	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
UC8_RS24090	COG0215	cysteine-tRNA ligase activity
UC8_RS24095	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
UC8_RS24100	COG0632	four-way junction helicase activity
UC8_RS24115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
UC8_RS24135	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
UC8_RS24140	COG0133	tryptophan synthase activity
UC8_RS24160	COG4948	Mandelate Racemase Muconate Lactonizing
UC8_RS24210	COG4536	flavin adenine dinucleotide binding
UC8_RS24215	COG4536	flavin adenine dinucleotide binding
UC8_RS24245	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
UC8_RS24270	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
UC8_RS24280	COG0515	serine threonine protein kinase
UC8_RS24280	COG2815	serine threonine protein kinase
UC8_RS24295	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
UC8_RS24305	COG1582	Flagellar protein (FlbD)
UC8_RS24310	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
UC8_RS24325	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
UC8_RS24325	COG1776	CheC inhibitor of MCP methylation
UC8_RS24355	COG1338	Plays a role in the flagellum-specific transport system
UC8_RS24370	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
UC8_RS24400	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
UC8_RS24405	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
UC8_RS24410	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
UC8_RS24420	COG0423	glycine-tRNA ligase activity
UC8_RS24435	COG0573	inorganic phosphate transmembrane transporter activity
UC8_RS24440	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
UC8_RS24475	COG0095	Lipoate-protein ligase
UC8_RS24480	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
UC8_RS24485	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
UC8_RS24490	COG0509	glycine decarboxylation via glycine cleavage system
UC8_RS24495	COG0404	The glycine cleavage system catalyzes the degradation of glycine
UC8_RS24510	COG3119	arylsulfatase activity
UC8_RS24520	COG1073	alpha beta
UC8_RS24525	COG0436	Aminotransferase
UC8_RS24540	COG2096	Adenosyltransferase
UC8_RS24545	COG0347	Belongs to the P(II) protein family
UC8_RS24595	COG2115	Belongs to the xylose isomerase family
UC8_RS24610	COG3344	reverse transcriptase
UC8_RS24630	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
UC8_RS24635	COG1419	protein localization to endoplasmic reticulum
UC8_RS24645	COG1191	sigma factor activity
UC8_RS24655	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
UC8_RS24660	COG0196	riboflavin kinase activity
UC8_RS24665	COG1691	(AIR) carboxylase
UC8_RS24670	COG0137	argininosuccinate synthase activity
UC8_RS24685	COG1490	D-aminoacyl-tRNA deacylase activity
UC8_RS24715	COG0825	malonyl-CoA metabolic process
UC8_RS24720	COG0515	serine threonine protein kinase
UC8_RS24735	COG0101	tRNA pseudouridine synthase activity
UC8_RS24740	COG1505	serine-type exopeptidase activity
UC8_RS24750	COG3958	Transketolase
UC8_RS24755	COG3959	Transketolase, thiamine diphosphate binding domain
UC8_RS24805	COG1086	Polysaccharide biosynthesis protein
UC8_RS24840	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
UC8_RS24870	COG3206	protein involved in exopolysaccharide biosynthesis
UC8_RS24870	COG0489	protein tyrosine kinase activity
UC8_RS24895	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
UC8_RS24900	COG0515	serine threonine protein kinase
UC8_RS24900	COG1262	PFAM Formylglycine-generating sulfatase enzyme
UC8_RS24910	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
UC8_RS24915	COG1904	glucuronate isomerase
UC8_RS24925	COG0557	exoribonuclease II activity
UC8_RS24935	COG3437	response regulator, receiver
UC8_RS24965	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
UC8_RS24970	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
UC8_RS25000	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
UC8_RS25005	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
UC8_RS25010	COG0243	molybdopterin cofactor binding
UC8_RS25015	COG0437	4 iron, 4 sulfur cluster binding
UC8_RS25020	COG1116	anion transmembrane transporter activity
UC8_RS25025	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
UC8_RS25025	COG1116	anion transmembrane transporter activity
UC8_RS25030	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
UC8_RS25035	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
UC8_RS25035	COG1116	anion transmembrane transporter activity
UC8_RS25090	COG0259	pyridoxamine-phosphate oxidase activity
UC8_RS25095	COG1678	Uncharacterized ACR, COG1678
UC8_RS25120	COG0848	biopolymer transport protein
UC8_RS25155	COG2852	Protein conserved in bacteria
UC8_RS25175	COG1115	amino acid carrier protein
UC8_RS25185	COG3119	arylsulfatase activity
UC8_RS25215	COG0217	transcriptional regulatory protein
UC8_RS25225	COG3341	Caulimovirus viroplasmin
UC8_RS25225	COG0328	RNA-DNA hybrid ribonuclease activity
UC8_RS25230	COG1252	NADH dehydrogenase
UC8_RS25270	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
UC8_RS25275	COG0800	Aldolase
UC8_RS25305	COG2815	serine threonine protein kinase
UC8_RS25305	COG0515	serine threonine protein kinase
UC8_RS25310	COG0517	IMP dehydrogenase activity
UC8_RS25310	COG1994	Peptidase M50
UC8_RS25320	COG0783	Belongs to the Dps family
UC8_RS25330	COG1253	flavin adenine dinucleotide binding
UC8_RS25340	COG2217	Heavy metal translocating P-type atpase
UC8_RS25360	COG4968	Prepilin-type N-terminal cleavage methylation domain
UC8_RS25365	COG1321	iron dependent repressor
UC8_RS25425	COG3119	arylsulfatase activity
UC8_RS25430	COG3119	arylsulfatase activity
UC8_RS25430	COG3408	Glycogen debranching enzyme
UC8_RS25435	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
UC8_RS25440	COG0033	Phosphoglucomutase
UC8_RS25445	COG0515	serine threonine protein kinase
UC8_RS25445	COG2815	serine threonine protein kinase
UC8_RS25450	COG0668	transmembrane transport
UC8_RS25495	COG3119	arylsulfatase activity
UC8_RS25505	COG3119	arylsulfatase activity
UC8_RS25515	COG3119	arylsulfatase activity
UC8_RS25520	COG3119	arylsulfatase activity
UC8_RS25525	COG3119	arylsulfatase activity
UC8_RS25575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
UC8_RS25620	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
UC8_RS25630	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
UC8_RS25635	COG1611	Belongs to the LOG family
UC8_RS25650	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
UC8_RS25655	COG0058	SHG alpha-glucan phosphorylase activity
UC8_RS25665	COG0786	glutamate:sodium symporter activity
UC8_RS25695	COG0586	Pfam SNARE associated Golgi protein
UC8_RS25700	COG1285	pathogenesis
UC8_RS25705	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
UC8_RS25710	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
UC8_RS25730	COG1028	Short-chain dehydrogenase reductase Sdr
UC8_RS25740	COG1183	phosphatidylcholine synthase activity
UC8_RS25750	COG3119	arylsulfatase activity
UC8_RS25755	COG0604	alcohol dehydrogenase
UC8_RS25770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
UC8_RS25775	COG2814	Major facilitator Superfamily
UC8_RS25830	COG3408	Glycogen debranching enzyme
UC8_RS25830	COG3119	arylsulfatase activity
UC8_RS25855	COG2815	serine threonine protein kinase
UC8_RS25855	COG0515	serine threonine protein kinase
UC8_RS25860	COG3119	arylsulfatase activity
UC8_RS25875	COG0515	serine threonine protein kinase
UC8_RS25875	COG2815	serine threonine protein kinase
UC8_RS25905	COG3385	transposase activity
UC8_RS25925	COG1620	l-lactate permease
UC8_RS25955	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
UC8_RS25960	COG1562	ergosterol biosynthetic process
UC8_RS25970	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
UC8_RS25985	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
UC8_RS26015	COG0714	Associated with various cellular activities
UC8_RS26030	COG2322	membrane
UC8_RS26050	COG0109	protoheme IX farnesyltransferase activity
UC8_RS26070	COG0151	Belongs to the GarS family
UC8_RS26075	COG2890	protein-(glutamine-N5) methyltransferase activity
UC8_RS26080	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
UC8_RS26085	COG0254	rRNA binding
UC8_RS26105	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
UC8_RS26140	COG0811	peptide transport
UC8_RS26165	COG0811	peptide transport
UC8_RS26215	COG2267	carboxylic ester hydrolase activity
UC8_RS26225	COG1757	Na H antiporter
UC8_RS26240	COG3852	Histidine kinase
UC8_RS26245	COG0745	RESPONSE REGULATOR receiver
UC8_RS26250	COG0445	tRNA wobble uridine modification
UC8_RS26270	COG0442	prolyl-tRNA aminoacylation
UC8_RS26300	COG0248	Ppx GppA phosphatase
UC8_RS26310	COG0129	dihydroxy-acid dehydratase activity
UC8_RS26440	COG1136	(ABC) transporter
UC8_RS26440	COG0577	efflux transmembrane transporter activity
UC8_RS26445	COG1136	(ABC) transporter
UC8_RS26445	COG0577	efflux transmembrane transporter activity
UC8_RS26455	COG0504	CTP synthase activity
UC8_RS26460	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
UC8_RS26495	COG3119	arylsulfatase activity
UC8_RS26570	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
UC8_RS26575	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
UC8_RS26580	COG0195	Participates in both transcription termination and antitermination
UC8_RS26590	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
UC8_RS26640	COG3852	Histidine kinase
UC8_RS26650	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
UC8_RS26660	COG1968	undecaprenyl-diphosphatase activity
UC8_RS26675	COG1321	iron dependent repressor
UC8_RS26680	COG0803	Belongs to the bacterial solute-binding protein 9 family
UC8_RS26685	COG1121	(ABC) transporter
UC8_RS26690	COG1321	iron dependent repressor
UC8_RS26690	COG1108	ABC-type Mn2 Zn2 transport systems permease components
UC8_RS26695	COG1108	ABC-type Mn2 Zn2 transport systems permease components
UC8_RS26720	COG1621	beta-fructofuranosidase activity
UC8_RS26765	COG0352	thiamine-phosphate diphosphorylase activity
UC8_RS26770	COG0488	(ABC) transporter
UC8_RS26780	COG2346	COG2346, Truncated hemoglobins
UC8_RS26790	COG0494	nUDIX hydrolase
UC8_RS26795	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
UC8_RS26800	COG0363	glucosamine-6-phosphate deaminase activity
UC8_RS26810	COG0658	competence protein
UC8_RS26810	COG2333	competence protein COMEC
UC8_RS26845	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
UC8_RS26855	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
UC8_RS26870	COG2200	EAL domain
UC8_RS26875	COG1222	aaa ATPase
UC8_RS26885	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
UC8_RS26890	COG0390	transport system, permease component
UC8_RS26895	COG1505	serine-type exopeptidase activity
UC8_RS26905	COG0515	serine threonine protein kinase
UC8_RS26905	COG2815	serine threonine protein kinase
UC8_RS26930	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
UC8_RS26940	COG0542	response to heat
UC8_RS26945	COG0542	response to heat
UC8_RS26950	COG0542	response to heat
UC8_RS26965	COG3119	arylsulfatase activity
UC8_RS27170	COG0305	Participates in initiation and elongation during chromosome replication
UC8_RS27195	COG2815	serine threonine protein kinase
UC8_RS27195	COG0515	serine threonine protein kinase
UC8_RS27230	COG1872	DUF167
UC8_RS27235	COG4796	Type ii and iii secretion system protein
UC8_RS27260	COG2770	Histidine kinase
UC8_RS27260	COG3437	response regulator, receiver
UC8_RS27275	COG5002	protein histidine kinase activity
UC8_RS27285	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
UC8_RS27290	COG1459	type II secretion system
UC8_RS27315	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
UC8_RS27330	COG3706	GGDEF domain
UC8_RS27350	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
UC8_RS27365	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
UC8_RS27385	COG1054	Belongs to the UPF0176 family
UC8_RS27420	COG0318	PFAM AMP-dependent synthetase and ligase
UC8_RS27435	COG3252	Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT
UC8_RS27450	COG2195	Cleaves the N-terminal amino acid of tripeptides
UC8_RS27455	COG0489	protein tyrosine kinase activity
UC8_RS27465	COG1994	Peptidase M50
UC8_RS27480	COG0542	response to heat
UC8_RS27495	COG4581	dead DEAH box helicase
UC8_RS27510	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
UC8_RS27515	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
UC8_RS27520	COG1028	Short-chain dehydrogenase reductase Sdr
UC8_RS27525	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
UC8_RS27530	COG0333	Belongs to the bacterial ribosomal protein bL32 family
UC8_RS27540	COG2030	dehydratase
UC8_RS27610	COG1643	Atp-dependent helicase
UC8_RS27660	COG1073	alpha beta
UC8_RS27685	COG0438	transferase activity, transferring glycosyl groups
UC8_RS27695	COG1187	pseudouridine synthase activity
UC8_RS27705	COG1482	cell wall glycoprotein biosynthetic process
UC8_RS27710	COG0805	protein transport
UC8_RS27720	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
UC8_RS27725	COG0429	hydrolase of the alpha beta-hydrolase fold
UC8_RS27730	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
UC8_RS27745	COG3153	acetyltransferase
UC8_RS27745	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
UC8_RS27750	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
UC8_RS27755	COG2239	Acts as a magnesium transporter
UC8_RS27760	COG5002	protein histidine kinase activity
UC8_RS27785	COG3002	Belongs to the UPF0753 family
UC8_RS27790	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
UC8_RS27875	COG0714	Associated with various cellular activities
UC8_RS27930	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
UC8_RS27930	COG0116	Belongs to the methyltransferase superfamily
UC8_RS27940	COG0431	NADPH-dependent FMN reductase
UC8_RS27940	COG3976	FMN-binding domain protein
UC8_RS27940	COG1053	succinate dehydrogenase
UC8_RS27945	COG0437	4 iron, 4 sulfur cluster binding
UC8_RS27995	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
UC8_RS28020	COG0668	transmembrane transport
UC8_RS28025	COG3119	arylsulfatase activity
UC8_RS28030	COG3119	arylsulfatase activity
UC8_RS28055	COG0095	Lipoate-protein ligase
UC8_RS28060	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
UC8_RS28075	COG0653	protein targeting
UC8_RS28085	COG2373	Large extracellular alpha-helical protein
UC8_RS28095	COG3119	arylsulfatase activity
UC8_RS28120	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
UC8_RS28150	COG1136	(ABC) transporter
UC8_RS28150	COG0577	efflux transmembrane transporter activity
UC8_RS28155	COG1136	(ABC) transporter
UC8_RS28160	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
UC8_RS28165	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
UC8_RS28175	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
UC8_RS28185	COG2081	HI0933 family
UC8_RS28200	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
UC8_RS28205	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
UC8_RS28210	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
UC8_RS28215	COG1233	COG1233 Phytoene dehydrogenase and related
UC8_RS28220	COG0528	UMP kinase activity
UC8_RS28225	COG0233	cytoplasmic translational termination
UC8_RS28235	COG0492	ferredoxin-NADP+ reductase activity
UC8_RS28245	COG0268	Binds directly to 16S ribosomal RNA
UC8_RS28255	COG3869	Catalyzes the specific phosphorylation of arginine residues in
UC8_RS28260	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
UC8_RS28300	COG3104	oligopeptide transport
UC8_RS28310	COG0657	acetylesterase activity
UC8_RS28310	COG2755	lipolytic protein G-D-S-L family
UC8_RS28325	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
UC8_RS28330	COG0367	asparagine synthase
UC8_RS28350	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
UC8_RS28360	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
UC8_RS28365	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
UC8_RS28385	COG3119	arylsulfatase activity
UC8_RS28400	COG1262	PFAM Formylglycine-generating sulfatase enzyme
UC8_RS28405	COG3119	arylsulfatase activity
UC8_RS28420	COG3118	belongs to the thioredoxin family
UC8_RS28430	COG0673	inositol 2-dehydrogenase activity
UC8_RS28440	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
UC8_RS28475	COG1917	Cupin 2, conserved barrel domain protein
UC8_RS28475	COG4977	sequence-specific DNA binding
UC8_RS28490	COG2391	methyltransferase activity
UC8_RS28495	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
UC8_RS28495	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
UC8_RS28520	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
UC8_RS28525	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
UC8_RS28530	COG1663	tetraacyldisaccharide 4'-kinase activity
UC8_RS28535	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
UC8_RS28540	COG1410	methionine synthase
UC8_RS28540	COG0646	methionine synthase
UC8_RS28575	COG0267	Belongs to the bacterial ribosomal protein bL33 family
UC8_RS28580	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
UC8_RS28580	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
UC8_RS28605	COG0569	domain protein
UC8_RS28665	COG4804	nuclease activity
UC8_RS28670	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
UC8_RS28675	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
UC8_RS28685	COG0653	protein targeting
UC8_RS28705	COG4191	Histidine kinase
UC8_RS28755	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
UC8_RS28770	COG3842	ATPase activity
UC8_RS28775	COG0473	3-isopropylmalate dehydrogenase activity
UC8_RS28795	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
UC8_RS28800	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
UC8_RS28810	COG3119	arylsulfatase activity
UC8_RS28820	COG3361	conserved protein (COG2071)
UC8_RS28825	COG0483	inositol monophosphate 1-phosphatase activity
UC8_RS28830	COG0667	Aldo Keto reductase
UC8_RS28845	COG1136	(ABC) transporter
UC8_RS28850	COG1136	(ABC) transporter
UC8_RS28850	COG0577	efflux transmembrane transporter activity
UC8_RS28860	COG0463	Glycosyl transferase, family 2
UC8_RS28865	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
UC8_RS28870	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
UC8_RS28910	COG2226	methyltransferase
UC8_RS28935	COG0745	RESPONSE REGULATOR receiver
UC8_RS28985	COG2855	membrane
UC8_RS29005	COG0515	serine threonine protein kinase
UC8_RS29005	COG2815	serine threonine protein kinase
UC8_RS29030	COG0443	Heat shock 70 kDa protein
UC8_RS29035	COG1573	uracil-dna glycosylase
UC8_RS29050	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
UC8_RS29115	COG0561	phosphatase activity
UC8_RS29115	COG3100	YcgL domain-containing protein
UC8_RS29125	COG0438	transferase activity, transferring glycosyl groups
UC8_RS29130	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
UC8_RS29160	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
UC8_RS29165	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
UC8_RS29175	COG1104	cysteine desulfurase activity