locus-tag	class	description
FIU91_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FIU91_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FIU91_RS00055	COG0402	S-adenosylhomocysteine deaminase activity
FIU91_RS00060	COG3781	membrane
FIU91_RS00065	COG0725	ABC transporter, periplasmic molybdate-binding protein
FIU91_RS00070	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FIU91_RS00075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIU91_RS00080	COG1120	ATPase activity
FIU91_RS00085	COG3585	molybdate ion transport
FIU91_RS00100	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FIU91_RS00105	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIU91_RS00140	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FIU91_RS00150	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FIU91_RS00155	COG0179	Fumarylacetoacetate (FAA) hydrolase
FIU91_RS00160	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FIU91_RS00170	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FIU91_RS00185	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FIU91_RS00190	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FIU91_RS00195	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FIU91_RS00200	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FIU91_RS00210	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FIU91_RS00220	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FIU91_RS00225	COG0508	dehydrogenase complex catalyzes the overall conversion of
FIU91_RS00230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FIU91_RS00235	COG3806	Anti-sigma factor
FIU91_RS00240	COG1595	DNA-templated transcription, initiation
FIU91_RS00265	COG1028	Short-chain dehydrogenase reductase Sdr
FIU91_RS00270	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FIU91_RS00280	COG0284	orotidine-5'-phosphate decarboxylase activity
FIU91_RS00295	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FIU91_RS00300	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FIU91_RS00305	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FIU91_RS00340	COG4166	transmembrane transport
FIU91_RS00350	COG0601	transmembrane transport
FIU91_RS00360	COG0444	Belongs to the ABC transporter superfamily
FIU91_RS00365	COG4608	Belongs to the ABC transporter superfamily
FIU91_RS00390	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FIU91_RS00395	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FIU91_RS00435	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FIU91_RS00440	COG0517	IMP dehydrogenase activity
FIU91_RS00440	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FIU91_RS00470	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FIU91_RS00470	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FIU91_RS00485	COG0489	protein tyrosine kinase activity
FIU91_RS00505	COG0297	glycogen (starch) synthase activity
FIU91_RS00525	COG1846	Transcriptional regulator
FIU91_RS00550	COG3591	Belongs to the peptidase S1B family
FIU91_RS00555	COG0247	lactate metabolic process
FIU91_RS00565	COG0277	FAD linked oxidase domain protein
FIU91_RS00570	COG0277	FAD linked oxidase domain protein
FIU91_RS00605	COG0714	Associated with various cellular activities
FIU91_RS00615	COG3622	Belongs to the hyi family
FIU91_RS00635	COG1131	(ABC) transporter
FIU91_RS00645	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FIU91_RS00645	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FIU91_RS00650	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIU91_RS00655	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FIU91_RS00665	COG2885	chlorophyll binding
FIU91_RS00670	COG0431	NADPH-dependent FMN reductase
FIU91_RS00680	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FIU91_RS00695	COG1137	ATPase activity
FIU91_RS00700	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FIU91_RS00705	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIU91_RS00740	COG1216	Glycosyl transferase, family 2
FIU91_RS00745	COG1218	3'(2'),5'-bisphosphate nucleotidase
FIU91_RS00765	COG0443	Heat shock 70 kDa protein
FIU91_RS00770	COG0484	heat shock protein binding
FIU91_RS00775	COG1902	pentaerythritol trinitrate reductase activity
FIU91_RS00775	COG0446	pyridine nucleotide-disulphide oxidoreductase
FIU91_RS00785	COG0242	peptide deformylase activity
FIU91_RS00790	COG0242	peptide deformylase activity
FIU91_RS00795	COG0242	peptide deformylase activity
FIU91_RS00800	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FIU91_RS00845	COG0138	bifunctional purine biosynthesis protein purh
FIU91_RS00850	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FIU91_RS00860	COG0612	Peptidase, M16
FIU91_RS00865	COG0612	Peptidase, M16
FIU91_RS00870	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FIU91_RS00875	COG0741	lytic transglycosylase activity
FIU91_RS00885	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIU91_RS00885	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FIU91_RS00890	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIU91_RS00890	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FIU91_RS00905	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FIU91_RS00920	COG0006	proline dipeptidase activity
FIU91_RS00925	COG3842	ATPase activity
FIU91_RS00945	COG1177	transmembrane transport
FIU91_RS00955	COG0730	response to heat
FIU91_RS00960	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FIU91_RS00965	COG1846	Transcriptional regulator
FIU91_RS00970	COG0745	RESPONSE REGULATOR receiver
FIU91_RS00975	COG2154	pterin-4-alpha-carbinolamine dehydratase
FIU91_RS00985	COG0584	glycerophosphoryl diester phosphodiesterase
FIU91_RS01005	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FIU91_RS01010	COG0347	Belongs to the P(II) protein family
FIU91_RS01015	COG0004	ammonium transporteR
FIU91_RS01030	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FIU91_RS01035	COG2897	thiosulfate sulfurtransferase activity
FIU91_RS01045	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FIU91_RS01050	COG0799	negative regulation of ribosome biogenesis
FIU91_RS01055	COG1012	belongs to the aldehyde dehydrogenase family
FIU91_RS01060	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FIU91_RS01065	COG0435	Glutathione S-transferase
FIU91_RS01100	COG0489	protein tyrosine kinase activity
FIU91_RS01100	COG2151	metal-sulfur cluster biosynthetic enzyme
FIU91_RS01120	COG0254	rRNA binding
FIU91_RS01125	COG0335	large ribosomal subunit rRNA binding
FIU91_RS01140	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FIU91_RS01150	COG0228	four-way junction DNA binding
FIU91_RS01185	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FIU91_RS01205	COG0356	it plays a direct role in the translocation of protons across the membrane
FIU91_RS01215	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FIU91_RS01220	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FIU91_RS01230	COG1194	a g-specific adenine glycosylase
FIU91_RS01240	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FIU91_RS01295	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FIU91_RS01300	COG1671	Belongs to the UPF0178 family
FIU91_RS01310	COG2423	ornithine cyclodeaminase activity
FIU91_RS01315	COG2267	carboxylic ester hydrolase activity
FIU91_RS01320	COG2271	Major facilitator Superfamily
FIU91_RS01330	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
FIU91_RS01415	COG0489	protein tyrosine kinase activity
FIU91_RS01425	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FIU91_RS01430	COG0285	dihydrofolate synthase activity
FIU91_RS01435	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FIU91_RS01495	COG0678	peroxiredoxin activity
FIU91_RS01505	COG0742	ribosomal rna small subunit methyltransferase
FIU91_RS01510	COG2814	Major facilitator Superfamily
FIU91_RS01515	COG0024	Methionine aminopeptidase
FIU91_RS01520	COG1489	DNA binding
FIU91_RS01525	COG1058	Belongs to the CinA family
FIU91_RS01525	COG1546	Belongs to the CinA family
FIU91_RS01545	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FIU91_RS01560	COG1238	metal cluster binding
FIU91_RS01570	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FIU91_RS01575	COG1758	RNA polymerase activity
FIU91_RS01580	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FIU91_RS01590	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FIU91_RS01600	COG0590	tRNA wobble adenosine to inosine editing
FIU91_RS01605	COG0736	holo-[acyl-carrier-protein] synthase activity
FIU91_RS01610	COG0681	Belongs to the peptidase S26 family
FIU91_RS01615	COG0571	ribonuclease III activity
FIU91_RS01625	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FIU91_RS01635	COG1381	Involved in DNA repair and RecF pathway recombination
FIU91_RS01640	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FIU91_RS01650	COG0314	molybdopterin synthase activity
FIU91_RS01670	COG3842	ATPase activity
FIU91_RS01675	COG1176	ABC-type spermidine putrescine transport system, permease component I
FIU91_RS01680	COG1177	transmembrane transport
FIU91_RS01685	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIU91_RS01710	COG0129	dihydroxy-acid dehydratase activity
FIU91_RS01715	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FIU91_RS01720	COG0772	Belongs to the SEDS family
FIU91_RS01725	COG0768	penicillin binding
FIU91_RS01750	COG0825	malonyl-CoA metabolic process
FIU91_RS01760	COG1956	GAF domain-containing protein
FIU91_RS01770	COG1280	lysine exporter protein (LysE YggA)
FIU91_RS01775	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FIU91_RS01775	COG0646	methionine synthase
FIU91_RS01780	COG0564	pseudouridine synthase activity
FIU91_RS01785	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FIU91_RS01790	COG0534	Mate efflux family protein
FIU91_RS01795	COG2835	tetraacyldisaccharide 4'-kinase activity
FIU91_RS01800	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FIU91_RS01805	COG3118	belongs to the thioredoxin family
FIU91_RS01820	COG2814	Major facilitator Superfamily
FIU91_RS01825	COG0450	alkyl hydroperoxide reductase
FIU91_RS01835	COG1802	Transcriptional regulator
FIU91_RS01855	COG1032	radical SAM domain protein
FIU91_RS01860	COG1719	4-vinyl reductase, 4VR
FIU91_RS01865	COG1234	tRNA 3'-trailer cleavage
FIU91_RS01875	COG0668	transmembrane transport
FIU91_RS01895	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FIU91_RS01900	COG0116	Belongs to the methyltransferase superfamily
FIU91_RS01900	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FIU91_RS01905	COG1185	polyribonucleotide nucleotidyltransferase activity
FIU91_RS01910	COG0745	RESPONSE REGULATOR receiver
FIU91_RS01920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FIU91_RS01930	COG1573	uracil-dna glycosylase
FIU91_RS01960	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIU91_RS01975	COG3191	aminopeptidase activity
FIU91_RS01980	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FIU91_RS01990	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FIU91_RS02015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FIU91_RS02025	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FIU91_RS02030	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FIU91_RS02035	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FIU91_RS02040	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FIU91_RS02045	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FIU91_RS02075	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FIU91_RS02090	COG0540	Belongs to the ATCase OTCase family
FIU91_RS02095	COG1573	uracil-dna glycosylase
FIU91_RS02100	COG0521	Mo-molybdopterin cofactor biosynthetic process
FIU91_RS02120	COG1678	Uncharacterized ACR, COG1678
FIU91_RS02125	COG0009	L-threonylcarbamoyladenylate synthase
FIU91_RS02130	COG1960	acyl-CoA dehydrogenase activity
FIU91_RS02170	COG0746	molybdenum cofactor guanylyltransferase activity
FIU91_RS02190	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FIU91_RS02210	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FIU91_RS02215	COG2115	Belongs to the xylose isomerase family
FIU91_RS02220	COG1070	Carbohydrate kinase
FIU91_RS02225	COG1129	ABC transporter
FIU91_RS02230	COG4214	carbohydrate transport
FIU91_RS02235	COG4213	ABC transporter substrate-binding protein
FIU91_RS02240	COG1940	carbohydrate kinase activity
FIU91_RS02250	COG1858	cytochrome C peroxidase
FIU91_RS02255	COG0142	geranyltranstransferase activity
FIU91_RS02275	COG0400	carboxylic ester hydrolase activity
FIU91_RS02280	COG0346	lactoylglutathione lyase activity
FIU91_RS02285	COG1028	Short-chain dehydrogenase reductase Sdr
FIU91_RS02300	COG2200	EAL domain
FIU91_RS02305	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FIU91_RS02315	COG1609	Transcriptional regulator
FIU91_RS02400	COG0006	proline dipeptidase activity
FIU91_RS02410	COG1473	amidohydrolase
FIU91_RS02420	COG1522	sequence-specific DNA binding
FIU91_RS02425	COG3328	transposase activity
FIU91_RS02445	COG0667	Aldo Keto reductase
FIU91_RS02460	COG0697	spore germination
FIU91_RS02465	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FIU91_RS02470	COG1522	sequence-specific DNA binding
FIU91_RS02480	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FIU91_RS02485	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FIU91_RS02500	COG0583	DNA-binding transcription factor activity
FIU91_RS02510	COG0477	Major facilitator Superfamily
FIU91_RS02535	COG0534	Mate efflux family protein
FIU91_RS02540	COG1280	lysine exporter protein (LysE YggA)
FIU91_RS02550	COG1537	nuclear-transcribed mRNA catabolic process, no-go decay
FIU91_RS02555	COG1431	PFAM Stem cell self-renewal protein Piwi
FIU91_RS02560	COG1078	dGTPase activity
FIU91_RS02600	COG4584	PFAM Integrase catalytic
FIU91_RS02600	COG2390	Transcriptional regulator
FIU91_RS02605	COG1484	DNA-dependent DNA replication
FIU91_RS02635	COG1280	lysine exporter protein (LysE YggA)
FIU91_RS02665	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FIU91_RS02725	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FIU91_RS02745	COG0527	aspartate kinase activity
FIU91_RS02750	COG1917	Cupin 2, conserved barrel domain protein
FIU91_RS02755	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FIU91_RS02775	COG0729	surface antigen
FIU91_RS02795	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FIU91_RS02800	COG0745	RESPONSE REGULATOR receiver
FIU91_RS02805	COG2205	protein histidine kinase activity
FIU91_RS02815	COG1660	Displays ATPase and GTPase activities
FIU91_RS02845	COG1201	RNA secondary structure unwinding
FIU91_RS02855	COG2304	oxidoreductase activity
FIU91_RS02870	COG1079	Belongs to the binding-protein-dependent transport system permease family
FIU91_RS02875	COG4603	Belongs to the binding-protein-dependent transport system permease family
FIU91_RS02880	COG3845	ABC transporter
FIU91_RS02905	COG0124	histidyl-tRNA synthetase
FIU91_RS02910	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FIU91_RS02915	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FIU91_RS02920	COG1376	ErfK ybiS ycfS ynhG family protein
FIU91_RS02930	COG2226	methyltransferase
FIU91_RS02935	COG0625	glutathione transferase activity
FIU91_RS02950	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FIU91_RS02955	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FIU91_RS02975	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FIU91_RS02980	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FIU91_RS03020	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FIU91_RS03020	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FIU91_RS03030	COG1999	signal sequence binding
FIU91_RS03035	COG0789	Transcriptional regulator
FIU91_RS03040	COG1742	UPF0060 membrane protein
FIU91_RS03045	COG0785	Cytochrome C biogenesis protein
FIU91_RS03065	COG1742	UPF0060 membrane protein
FIU91_RS03070	COG0789	Transcriptional regulator
FIU91_RS03120	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FIU91_RS03155	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FIU91_RS03160	COG0730	response to heat
FIU91_RS03165	COG0501	Belongs to the peptidase M48B family
FIU91_RS03225	COG0714	Associated with various cellular activities
FIU91_RS03235	COG2010	Cytochrome c
FIU91_RS03265	COG5002	protein histidine kinase activity
FIU91_RS03265	COG0784	Response regulator, receiver
FIU91_RS03265	COG2198	Histidine kinase
FIU91_RS03275	COG0659	secondary active sulfate transmembrane transporter activity
FIU91_RS03280	COG0589	response to stress
FIU91_RS03285	COG1732	Glycine betaine
FIU91_RS03290	COG1174	glycine betaine transport
FIU91_RS03295	COG1125	glycine betaine transport
FIU91_RS03300	COG1174	glycine betaine transport
FIU91_RS03305	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FIU91_RS03350	COG0420	3'-5' exonuclease activity
FIU91_RS03355	COG0419	ATPase involved in DNA repair
FIU91_RS03495	COG0667	Aldo Keto reductase
FIU91_RS03500	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FIU91_RS03505	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FIU91_RS03515	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FIU91_RS03520	COG3246	L-lysine catabolic process to acetate
FIU91_RS03525	COG3485	protocatechuate 3,4-dioxygenase
FIU91_RS03530	COG3485	protocatechuate 3,4-dioxygenase
FIU91_RS03540	COG0583	DNA-binding transcription factor activity
FIU91_RS03565	COG1012	belongs to the aldehyde dehydrogenase family
FIU91_RS03630	COG4221	oxidoreductase activity
FIU91_RS03635	COG0583	DNA-binding transcription factor activity
FIU91_RS03640	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FIU91_RS03645	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FIU91_RS03740	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIU91_RS03745	COG1737	Transcriptional regulator
FIU91_RS03750	COG1172	Belongs to the binding-protein-dependent transport system permease family
FIU91_RS03770	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FIU91_RS03790	COG1937	Protein conserved in bacteria
FIU91_RS03805	COG1376	ErfK ybiS ycfS ynhG family protein
FIU91_RS03830	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FIU91_RS03835	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FIU91_RS03880	COG0582	viral genome integration into host DNA
FIU91_RS03965	COG3214	Protein conserved in bacteria
FIU91_RS03975	COG0513	Belongs to the DEAD box helicase family
FIU91_RS04010	COG0745	RESPONSE REGULATOR receiver
FIU91_RS04015	COG2205	protein histidine kinase activity
FIU91_RS04050	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FIU91_RS04055	COG0569	domain protein
FIU91_RS04075	COG0318	PFAM AMP-dependent synthetase and ligase
FIU91_RS04085	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FIU91_RS04105	COG4989	oxidoreductase activity
FIU91_RS04120	COG0673	inositol 2-dehydrogenase activity
FIU91_RS04140	COG1116	anion transmembrane transporter activity
FIU91_RS04150	COG1346	cytolysis
FIU91_RS04160	COG4136	ATPase activity
FIU91_RS04165	COG4135	transport system, permease component
FIU91_RS04170	COG4134	Bacterial extracellular solute-binding protein
FIU91_RS04175	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FIU91_RS04185	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FIU91_RS04185	COG3008	intermembrane lipid transfer
FIU91_RS04190	COG2995	paraquat-inducible protein a
FIU91_RS04200	COG1305	Transglutaminase-like
FIU91_RS04205	COG0446	pyridine nucleotide-disulphide oxidoreductase
FIU91_RS04205	COG1902	pentaerythritol trinitrate reductase activity
FIU91_RS04210	COG4638	Rieske (2fe-2S)
FIU91_RS04235	COG0183	Belongs to the thiolase family
FIU91_RS04250	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FIU91_RS04265	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIU91_RS04275	COG1024	Enoyl-CoA hydratase
FIU91_RS04275	COG1250	3-hydroxyacyl-CoA dehydrogenase
FIU91_RS04280	COG0183	Belongs to the thiolase family
FIU91_RS04285	COG1960	acyl-CoA dehydrogenase activity
FIU91_RS04290	COG1960	acyl-CoA dehydrogenase activity
FIU91_RS04300	COG0318	PFAM AMP-dependent synthetase and ligase
FIU91_RS04305	COG2391	methyltransferase activity
FIU91_RS04315	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FIU91_RS04315	COG2111	Na H antiporter
FIU91_RS04320	COG1006	Multisubunit Na H antiporter MnhC subunit
FIU91_RS04325	COG0651	ATP synthesis coupled electron transport
FIU91_RS04330	COG1863	multisubunit Na H antiporter MnhE subunit
FIU91_RS04335	COG2212	antiporter activity
FIU91_RS04340	COG1320	monovalent cation:proton antiporter activity
FIU91_RS04365	COG3706	GGDEF domain
FIU91_RS04370	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FIU91_RS04380	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FIU91_RS04385	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FIU91_RS04390	COG1643	Atp-dependent helicase
FIU91_RS04395	COG0339	signal peptide processing
FIU91_RS04415	COG3654	unkown
FIU91_RS04420	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FIU91_RS04425	COG0459	protein refolding
FIU91_RS04430	COG1028	Short-chain dehydrogenase reductase Sdr
FIU91_RS04450	COG1228	amidohydrolase
FIU91_RS04455	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FIU91_RS04460	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FIU91_RS04480	COG2046	Belongs to the sulfate adenylyltransferase family
FIU91_RS04480	COG0529	Catalyzes the synthesis of activated sulfate
FIU91_RS04490	COG1917	Cupin 2, conserved barrel domain protein
FIU91_RS04495	COG0492	ferredoxin-NADP+ reductase activity
FIU91_RS04500	COG1522	sequence-specific DNA binding
FIU91_RS04510	COG1496	oxidoreductase activity
FIU91_RS04520	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FIU91_RS04545	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FIU91_RS04550	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FIU91_RS04555	COG1183	phosphatidylcholine synthase activity
FIU91_RS04560	COG0842	Transport permease protein
FIU91_RS04595	COG1435	thymidine kinase activity
FIU91_RS04605	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FIU91_RS04620	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FIU91_RS04620	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FIU91_RS04625	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FIU91_RS04630	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FIU91_RS04680	COG0564	pseudouridine synthase activity
FIU91_RS04690	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FIU91_RS04710	COG3243	poly(R)-hydroxyalkanoic acid synthase
FIU91_RS04725	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FIU91_RS04730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIU91_RS04735	COG0174	glutamine synthetase
FIU91_RS04745	COG0174	glutamine synthetase
FIU91_RS04750	COG4160	amino acid transport
FIU91_RS04755	COG4215	(ABC) transporter
FIU91_RS04780	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FIU91_RS04795	COG0504	CTP synthase activity
FIU91_RS04815	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FIU91_RS04830	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FIU91_RS04855	COG0488	(ABC) transporter
FIU91_RS04865	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FIU91_RS04890	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FIU91_RS04905	COG0556	nucleotide-excision repair
FIU91_RS04920	COG0149	triose-phosphate isomerase activity
FIU91_RS04925	COG0316	Belongs to the HesB IscA family
FIU91_RS04940	COG0110	maltose O-acetyltransferase activity
FIU91_RS04955	COG2151	metal-sulfur cluster biosynthetic enzyme
FIU91_RS04985	COG4948	Mandelate Racemase Muconate Lactonizing
FIU91_RS05010	COG0601	transmembrane transport
FIU91_RS05015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIU91_RS05020	COG4172	Belongs to the ABC transporter superfamily
FIU91_RS05025	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FIU91_RS05060	COG0437	4 iron, 4 sulfur cluster binding
FIU91_RS05065	COG3383	formate dehydrogenase (NAD+) activity
FIU91_RS05065	COG0243	molybdopterin cofactor binding
FIU91_RS05105	COG1469	GTP cyclohydrolase I activity
FIU91_RS05110	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FIU91_RS05115	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FIU91_RS05120	COG1127	ABC transporter
FIU91_RS05125	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FIU91_RS05125	COG3218	ABC-type transport auxiliary lipoprotein component
FIU91_RS05135	COG0069	glutamate synthase activity
FIU91_RS05150	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FIU91_RS05175	COG3220	belongs to the UPF0276 family
FIU91_RS05205	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FIU91_RS05210	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FIU91_RS05220	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FIU91_RS05230	COG3768	UPF0283 membrane protein
FIU91_RS05235	COG3106	COG3106 Predicted ATPase
FIU91_RS05240	COG0101	tRNA pseudouridine synthase activity
FIU91_RS05250	COG3046	protein related to deoxyribodipyrimidine photolyase
FIU91_RS05280	COG0655	NAD(P)H dehydrogenase (quinone) activity
FIU91_RS05285	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FIU91_RS05290	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FIU91_RS05300	COG1959	2 iron, 2 sulfur cluster binding
FIU91_RS05305	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FIU91_RS05310	COG0509	glycine decarboxylation via glycine cleavage system
FIU91_RS05315	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FIU91_RS05315	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FIU91_RS05320	COG0483	inositol monophosphate 1-phosphatase activity
FIU91_RS05325	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FIU91_RS05330	COG4181	ATPase activity
FIU91_RS05345	COG1278	Cold shock
FIU91_RS05365	COG1376	ErfK ybiS ycfS ynhG family protein
FIU91_RS05370	COG1047	Peptidyl-prolyl cis-trans
FIU91_RS05380	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FIU91_RS05390	COG0725	ABC transporter, periplasmic molybdate-binding protein
FIU91_RS05395	COG4149	molybdate abc transporter
FIU91_RS05400	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FIU91_RS05405	COG0667	Aldo Keto reductase
FIU91_RS05415	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FIU91_RS05425	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FIU91_RS05440	COG0513	Belongs to the DEAD box helicase family
FIU91_RS05475	COG1028	Short-chain dehydrogenase reductase Sdr
FIU91_RS05480	COG4335	DNA alkylation repair
FIU91_RS05485	COG0501	Belongs to the peptidase M48B family
FIU91_RS05490	COG1764	response to oxidative stress
FIU91_RS05515	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FIU91_RS05525	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FIU91_RS05530	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FIU91_RS05540	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FIU91_RS05555	COG0175	sulfate reduction
FIU91_RS05560	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FIU91_RS05570	COG1648	precorrin-2 dehydrogenase activity
FIU91_RS05570	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FIU91_RS05575	COG1522	sequence-specific DNA binding
FIU91_RS05580	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FIU91_RS05615	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FIU91_RS05620	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FIU91_RS05635	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FIU91_RS05640	COG1181	Belongs to the D-alanine--D-alanine ligase family
FIU91_RS05645	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FIU91_RS05650	COG0849	cell division
FIU91_RS05655	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FIU91_RS05660	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FIU91_RS05665	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FIU91_RS05685	COG0006	proline dipeptidase activity
FIU91_RS05695	COG1692	metallophosphoesterase
FIU91_RS05710	COG0489	protein tyrosine kinase activity
FIU91_RS05745	COG0187	DNA topoisomerase II activity
FIU91_RS05750	COG0697	spore germination
FIU91_RS05760	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FIU91_RS05765	COG0049	tRNA binding
FIU91_RS05770	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FIU91_RS05775	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FIU91_RS05780	COG0051	transcription antitermination factor activity, RNA binding
FIU91_RS05785	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FIU91_RS05790	COG0088	Forms part of the polypeptide exit tunnel
FIU91_RS05795	COG0089	rRNA binding
FIU91_RS05800	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FIU91_RS05805	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FIU91_RS05810	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FIU91_RS05815	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FIU91_RS05820	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FIU91_RS05830	COG0255	Belongs to the universal ribosomal protein uL29 family
FIU91_RS05835	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FIU91_RS05840	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FIU91_RS05845	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FIU91_RS05850	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FIU91_RS05855	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FIU91_RS05860	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FIU91_RS05865	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FIU91_RS05870	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FIU91_RS05875	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FIU91_RS05880	COG1841	ribosomal large subunit assembly
FIU91_RS05885	COG0200	Binds to the 23S rRNA
FIU91_RS05890	COG0201	protein transport
FIU91_RS05895	COG0563	adenylate kinase activity
FIU91_RS05900	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FIU91_RS05905	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FIU91_RS05910	COG0202	RNA polymerase activity
FIU91_RS05920	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FIU91_RS05925	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FIU91_RS05930	COG4067	protein conserved in archaea
FIU91_RS05930	COG0189	ligase activity
FIU91_RS05935	COG0343	queuine tRNA-ribosyltransferase activity
FIU91_RS05960	COG1902	pentaerythritol trinitrate reductase activity
FIU91_RS05965	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FIU91_RS05970	COG0776	regulation of translation
FIU91_RS06030	COG0577	efflux transmembrane transporter activity
FIU91_RS06035	COG1136	(ABC) transporter
FIU91_RS06055	COG3108	Peptidase M15
FIU91_RS06065	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FIU91_RS06070	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FIU91_RS06080	COG1035	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
FIU91_RS06085	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FIU91_RS06095	COG2081	HI0933 family
FIU91_RS06100	COG0596	Alpha beta hydrolase
FIU91_RS06110	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FIU91_RS06120	COG0670	Belongs to the BI1 family
FIU91_RS06135	COG1028	Short-chain dehydrogenase reductase Sdr
FIU91_RS06135	COG0604	alcohol dehydrogenase
FIU91_RS06135	COG3321	synthase
FIU91_RS06145	COG0483	inositol monophosphate 1-phosphatase activity
FIU91_RS06160	COG0402	S-adenosylhomocysteine deaminase activity
FIU91_RS06165	COG2239	Acts as a magnesium transporter
FIU91_RS06170	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FIU91_RS06195	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FIU91_RS06200	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FIU91_RS06220	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FIU91_RS06235	COG0308	aminopeptidase N
FIU91_RS06265	COG5328	Belongs to the UPF0262 family
FIU91_RS06270	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FIU91_RS06280	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FIU91_RS06290	COG2116	formate transmembrane transporter activity
FIU91_RS06310	COG0084	hydrolase, TatD family'
FIU91_RS06320	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FIU91_RS06325	COG1686	Belongs to the peptidase S11 family
FIU91_RS06340	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FIU91_RS06410	COG1278	Cold shock
FIU91_RS06420	COG0628	permease
FIU91_RS06435	COG1609	Transcriptional regulator
FIU91_RS06445	COG0673	inositol 2-dehydrogenase activity
FIU91_RS06450	COG1129	ABC transporter
FIU91_RS06455	COG1172	Belongs to the binding-protein-dependent transport system permease family
FIU91_RS06460	COG1879	ABC-type sugar transport system periplasmic component
FIU91_RS06475	COG0395	ABC-type sugar transport system, permease component
FIU91_RS06490	COG3842	ATPase activity
FIU91_RS06500	COG1349	DNA-binding transcription factor activity
FIU91_RS06515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIU91_RS06525	COG1028	Short-chain dehydrogenase reductase Sdr
FIU91_RS06530	COG1028	Short-chain dehydrogenase reductase Sdr
FIU91_RS06535	COG0006	proline dipeptidase activity
FIU91_RS06550	COG1879	ABC-type sugar transport system periplasmic component
FIU91_RS06555	COG1028	Short-chain dehydrogenase reductase Sdr
FIU91_RS06560	COG1172	Belongs to the binding-protein-dependent transport system permease family
FIU91_RS06565	COG1172	Belongs to the binding-protein-dependent transport system permease family
FIU91_RS06570	COG1129	ABC transporter
FIU91_RS06575	COG2084	Dehydrogenase
FIU91_RS06585	COG0179	Fumarylacetoacetate (FAA) hydrolase
FIU91_RS06595	COG2169	Transcriptional regulator
FIU91_RS06595	COG1917	Cupin 2, conserved barrel domain protein
FIU91_RS06610	COG1028	Short-chain dehydrogenase reductase Sdr
FIU91_RS06620	COG1960	acyl-CoA dehydrogenase activity
FIU91_RS06635	COG0183	Belongs to the thiolase family
FIU91_RS06645	COG2030	dehydratase
FIU91_RS06650	COG1024	Enoyl-CoA hydratase
FIU91_RS06685	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FIU91_RS06695	COG1960	acyl-CoA dehydrogenase activity
FIU91_RS06705	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
FIU91_RS06715	COG1960	acyl-CoA dehydrogenase activity
FIU91_RS06725	COG0667	Aldo Keto reductase
FIU91_RS06740	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FIU91_RS06740	COG1181	Belongs to the D-alanine--D-alanine ligase family
FIU91_RS06775	COG2351	hydroxyisourate hydrolase activity
FIU91_RS06780	COG3648	Uricase
FIU91_RS06780	COG3195	allantoin biosynthetic process
FIU91_RS06785	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FIU91_RS06790	COG3257	ureidoglycine aminohydrolase activity
FIU91_RS06815	COG1294	oxidase, subunit
FIU91_RS06820	COG1271	oxidase subunit
FIU91_RS06845	COG0655	NAD(P)H dehydrogenase (quinone) activity
FIU91_RS06855	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIU91_RS06885	COG1120	ATPase activity
FIU91_RS06895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIU91_RS06905	COG0583	DNA-binding transcription factor activity
FIU91_RS06915	COG0523	cobalamin synthesis protein
FIU91_RS06935	COG1136	(ABC) transporter
FIU91_RS06935	COG0577	efflux transmembrane transporter activity
FIU91_RS06955	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FIU91_RS06955	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FIU91_RS06985	COG0483	inositol monophosphate 1-phosphatase activity
FIU91_RS07010	COG4974	Belongs to the 'phage' integrase family
FIU91_RS07055	COG3436	PFAM IS66 Orf2 family protein
FIU91_RS07060	COG4372	Transposase
FIU91_RS07065	COG3012	SEC-C Motif Domain Protein
FIU91_RS07080	COG0318	PFAM AMP-dependent synthetase and ligase
FIU91_RS07140	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FIU91_RS07200	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
FIU91_RS07205	COG0709	Synthesizes selenophosphate from selenide and ATP
FIU91_RS07210	COG2308	Evidence 4 Homologs of previously reported genes of
FIU91_RS07230	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
FIU91_RS07240	COG1091	dTDP-4-dehydrorhamnose reductase activity
FIU91_RS07245	COG1088	dTDP-glucose 4,6-dehydratase activity
FIU91_RS07275	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FIU91_RS07285	COG1216	Glycosyl transferase, family 2
FIU91_RS07295	COG0110	maltose O-acetyltransferase activity
FIU91_RS07315	COG1215	transferase activity, transferring glycosyl groups
FIU91_RS07330	COG0438	transferase activity, transferring glycosyl groups
FIU91_RS07355	COG1172	Belongs to the binding-protein-dependent transport system permease family
FIU91_RS07370	COG0583	DNA-binding transcription factor activity
FIU91_RS07415	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FIU91_RS07435	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FIU91_RS07440	COG3001	Fructosamine kinase
FIU91_RS07445	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FIU91_RS07450	COG1132	(ABC) transporter
FIU91_RS07460	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FIU91_RS07470	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FIU91_RS07480	COG0702	epimerase
FIU91_RS07490	COG1136	(ABC) transporter
FIU91_RS07515	COG1309	transcriptional regulator
FIU91_RS07535	COG1494	fructose-1,6-bisphosphatase
FIU91_RS07540	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FIU91_RS07600	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FIU91_RS07615	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FIU91_RS07625	COG0800	Aldolase
FIU91_RS07630	COG0129	dihydroxy-acid dehydratase activity
FIU91_RS07650	COG3842	ATPase activity
FIU91_RS07655	COG2378	regulation of single-species biofilm formation
FIU91_RS07660	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FIU91_RS07665	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FIU91_RS07670	COG0805	protein transport
FIU91_RS07690	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FIU91_RS07710	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FIU91_RS07735	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FIU91_RS07740	COG0305	Participates in initiation and elongation during chromosome replication
FIU91_RS07745	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FIU91_RS07750	COG0418	dihydroorotase activity
FIU91_RS07795	COG2885	chlorophyll binding
FIU91_RS07805	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FIU91_RS07805	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FIU91_RS07815	COG0303	'Molybdopterin
FIU91_RS07820	COG0315	cyclic pyranopterin monophosphate synthase activity
FIU91_RS07830	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FIU91_RS07835	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FIU91_RS07855	COG5012	cobalamin binding
FIU91_RS07865	COG1410	methionine synthase
FIU91_RS07865	COG0646	methionine synthase
FIU91_RS07875	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FIU91_RS07880	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FIU91_RS07885	COG0047	phosphoribosylformylglycinamidine synthase activity
FIU91_RS07895	COG2204	response regulator
FIU91_RS07900	COG2423	ornithine cyclodeaminase activity
FIU91_RS07905	COG0010	Belongs to the arginase family
FIU91_RS07915	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FIU91_RS07920	COG1238	metal cluster binding
FIU91_RS07935	COG2205	protein histidine kinase activity
FIU91_RS07945	COG3639	organic phosphonate transmembrane transporter activity
FIU91_RS07950	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FIU91_RS07975	COG0811	peptide transport
FIU91_RS08005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIU91_RS08010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIU91_RS08015	COG1120	ATPase activity
FIU91_RS08035	COG0783	Belongs to the Dps family
FIU91_RS08040	COG4774	siderophore transport
FIU91_RS08045	COG3720	iron ion transport
FIU91_RS08050	COG4558	Periplasmic binding protein
FIU91_RS08055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIU91_RS08060	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FIU91_RS08085	COG4536	flavin adenine dinucleotide binding
FIU91_RS08090	COG4974	Belongs to the 'phage' integrase family
FIU91_RS08100	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FIU91_RS08105	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FIU91_RS08110	COG1994	Peptidase M50
FIU91_RS08115	COG0629	single-stranded DNA binding
FIU91_RS08120	COG0741	lytic transglycosylase activity
FIU91_RS08140	COG0528	UMP kinase activity
FIU91_RS08145	COG0233	cytoplasmic translational termination
FIU91_RS08160	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FIU91_RS08165	COG0750	zinc metalloprotease
FIU91_RS08170	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FIU91_RS08180	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FIU91_RS08185	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FIU91_RS08190	COG3494	Protein of unknown function (DUF1009)
FIU91_RS08195	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FIU91_RS08205	COG0433	COG0433 Predicted ATPase
FIU91_RS08215	COG1247	-acetyltransferase
FIU91_RS08220	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FIU91_RS08235	COG0248	Ppx GppA phosphatase
FIU91_RS08240	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FIU91_RS08245	COG2255	four-way junction helicase activity
FIU91_RS08250	COG0628	permease
FIU91_RS08255	COG0442	prolyl-tRNA aminoacylation
FIU91_RS08265	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FIU91_RS08270	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FIU91_RS08275	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FIU91_RS08280	COG3773	Cell wall hydrolase
FIU91_RS08280	COG3409	Peptidoglycan-binding domain 1 protein
FIU91_RS08285	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FIU91_RS08285	COG0574	Belongs to the PEP-utilizing enzyme family
FIU91_RS08290	COG0751	glycine-tRNA ligase activity
FIU91_RS08305	COG0752	glycyl-tRNA synthetase alpha subunit
FIU91_RS08315	COG0697	spore germination
FIU91_RS08325	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FIU91_RS08325	COG1648	precorrin-2 dehydrogenase activity
FIU91_RS08330	COG1797	cobyrinic acid a,c-diamide synthase activity
FIU91_RS08335	COG2875	Belongs to the precorrin methyltransferase family
FIU91_RS08350	COG2099	Precorrin-6x reductase
FIU91_RS08395	COG1492	cobalamin metabolic process
FIU91_RS08405	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FIU91_RS08425	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FIU91_RS08430	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FIU91_RS08435	COG1840	ABC-type Fe3 transport system, periplasmic component
FIU91_RS08445	COG1178	ABC-type Fe3 transport system permease component
FIU91_RS08470	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FIU91_RS08475	COG1121	(ABC) transporter
FIU91_RS08485	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FIU91_RS08495	COG3485	protocatechuate 3,4-dioxygenase
FIU91_RS08500	COG3485	protocatechuate 3,4-dioxygenase
FIU91_RS08505	COG3396	Phenylacetate-CoA oxygenase
FIU91_RS08510	COG3460	Phenylacetate-CoA oxygenase
FIU91_RS08515	COG3396	Phenylacetate-CoA oxygenase
FIU91_RS08520	COG2151	metal-sulfur cluster biosynthetic enzyme
FIU91_RS08525	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FIU91_RS08530	COG2030	dehydratase
FIU91_RS08530	COG1012	belongs to the aldehyde dehydrogenase family
FIU91_RS08535	COG1309	transcriptional regulator
FIU91_RS08555	COG1175	transmembrane transport
FIU91_RS08620	COG1230	cation diffusion facilitator family transporter
FIU91_RS08625	COG0398	Pfam SNARE associated Golgi protein
FIU91_RS08660	COG1138	Cytochrome C-type biogenesis protein
FIU91_RS08665	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FIU91_RS08670	COG3088	subunit of a heme lyase
FIU91_RS08675	COG4235	cytochrome complex assembly
FIU91_RS08705	COG2010	Cytochrome c
FIU91_RS08710	COG2132	Multicopper oxidase
FIU91_RS08720	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FIU91_RS08720	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FIU91_RS08730	COG2217	Heavy metal translocating P-type atpase
FIU91_RS08755	COG2132	Multicopper oxidase
FIU91_RS08785	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FIU91_RS08810	COG2814	Major facilitator Superfamily
FIU91_RS08815	COG1937	Protein conserved in bacteria
FIU91_RS08840	COG2948	multi-organism process
FIU91_RS08855	COG3846	protein secretion by the type IV secretion system
FIU91_RS08870	COG3451	type IV secretory pathway VirB4
FIU91_RS08885	COG4962	Type ii secretion system protein e
FIU91_RS08890	COG1230	cation diffusion facilitator family transporter
FIU91_RS08945	COG0741	lytic transglycosylase activity
FIU91_RS08975	COG1396	sequence-specific DNA binding
FIU91_RS08975	COG3800	Transcriptional regulator
FIU91_RS09010	COG5489	Protein of unknown function (DUF736)
FIU91_RS09055	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FIU91_RS09070	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FIU91_RS09080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIU91_RS09090	COG0446	pyridine nucleotide-disulphide oxidoreductase
FIU91_RS09090	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FIU91_RS09130	COG0583	DNA-binding transcription factor activity
FIU91_RS09135	COG1960	acyl-CoA dehydrogenase activity
FIU91_RS09140	COG0022	dehydrogenase e1 component
FIU91_RS09145	COG2197	response regulator
FIU91_RS09150	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FIU91_RS09155	COG0052	Belongs to the universal ribosomal protein uS2 family
FIU91_RS09170	COG2313	pseudouridylate synthase activity
FIU91_RS09190	COG0745	RESPONSE REGULATOR receiver
FIU91_RS09200	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FIU91_RS09210	COG0573	inorganic phosphate transmembrane transporter activity
FIU91_RS09220	COG1272	protein, Hemolysin III
FIU91_RS09230	COG5002	protein histidine kinase activity
FIU91_RS09235	COG0626	cystathionine gamma-synthase activity
FIU91_RS09245	COG0194	GDP metabolic process
FIU91_RS09250	COG1561	YicC-like family, N-terminal region
FIU91_RS09265	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FIU91_RS09275	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
FIU91_RS09280	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FIU91_RS09315	COG1172	Belongs to the binding-protein-dependent transport system permease family
FIU91_RS09330	COG0784	Response regulator, receiver
FIU91_RS09330	COG2205	protein histidine kinase activity
FIU91_RS09350	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FIU91_RS09360	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FIU91_RS09380	COG0784	Response regulator, receiver
FIU91_RS09390	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FIU91_RS09395	COG0563	adenylate kinase activity
FIU91_RS09405	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FIU91_RS09410	COG0517	IMP dehydrogenase activity
FIU91_RS09410	COG1125	glycine betaine transport
FIU91_RS09420	COG5002	protein histidine kinase activity
FIU91_RS09420	COG2176	DNA-directed DNA polymerase activity
FIU91_RS09425	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FIU91_RS09430	COG3842	ATPase activity
FIU91_RS09435	COG0366	Alpha amylase catalytic
FIU91_RS09440	COG0395	ABC-type sugar transport system, permease component
FIU91_RS09445	COG1175	transmembrane transport
FIU91_RS09450	COG1653	transport
FIU91_RS09455	COG1609	Transcriptional regulator
FIU91_RS09460	COG2723	6-phospho-beta-galactosidase activity
FIU91_RS09465	COG0837	glucose binding
FIU91_RS09470	COG0058	SHG alpha-glucan phosphorylase activity
FIU91_RS09475	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FIU91_RS09485	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FIU91_RS09490	COG0297	glycogen (starch) synthase activity
FIU91_RS09500	COG0033	Phosphoglucomutase
FIU91_RS09520	COG0123	including yeast histone deacetylase and acetoin utilization protein
FIU91_RS09530	COG0488	(ABC) transporter
FIU91_RS09550	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FIU91_RS09555	COG0416	fatty acid biosynthetic process
FIU91_RS09560	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FIU91_RS09565	COG0776	regulation of translation
FIU91_RS09580	COG0717	Belongs to the dCTP deaminase family
FIU91_RS09595	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FIU91_RS09600	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FIU91_RS09605	COG1472	Belongs to the glycosyl hydrolase 3 family
FIU91_RS09615	COG0018	arginyl-trna synthetase
FIU91_RS09625	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FIU91_RS09630	COG0316	Belongs to the HesB IscA family
FIU91_RS09660	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FIU91_RS09675	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FIU91_RS09680	COG2133	pyrroloquinoline quinone binding
FIU91_RS09685	COG2354	Protein conserved in bacteria
FIU91_RS09705	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FIU91_RS09710	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FIU91_RS09710	COG0617	tRNA 3'-terminal CCA addition
FIU91_RS09710	COG0517	IMP dehydrogenase activity
FIU91_RS09725	COG1960	acyl-CoA dehydrogenase activity
FIU91_RS09745	COG2010	Cytochrome c
FIU91_RS09750	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FIU91_RS09760	COG5598	trimethylamine methyltransferase
FIU91_RS09765	COG0519	Catalyzes the synthesis of GMP from XMP
FIU91_RS09765	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FIU91_RS09775	COG0697	spore germination
FIU91_RS09795	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FIU91_RS09805	COG2326	polyphosphate kinase activity
FIU91_RS09810	COG1309	transcriptional regulator
FIU91_RS09815	COG1160	GTP binding
FIU91_RS09835	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIU91_RS09840	COG5265	(ABC) transporter
FIU91_RS09850	COG1028	Short-chain dehydrogenase reductase Sdr
FIU91_RS09855	COG4166	transmembrane transport
FIU91_RS09875	COG0538	isocitrate dehydrogenase activity
FIU91_RS09900	COG0348	domain, Protein
FIU91_RS09905	COG2010	Cytochrome c
FIU91_RS09925	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FIU91_RS09930	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FIU91_RS09940	COG0745	RESPONSE REGULATOR receiver
FIU91_RS09945	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FIU91_RS09975	COG0840	transmembrane signaling receptor activity
FIU91_RS09985	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FIU91_RS10000	COG1278	Cold shock
FIU91_RS10005	COG0259	pyridoxamine-phosphate oxidase activity
FIU91_RS10010	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FIU91_RS10015	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FIU91_RS10025	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FIU91_RS10030	COG2166	iron-sulfur cluster assembly
FIU91_RS10040	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FIU91_RS10045	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FIU91_RS10050	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FIU91_RS10090	COG2133	pyrroloquinoline quinone binding
FIU91_RS10110	COG0427	acetyl-CoA hydrolase
FIU91_RS10115	COG1250	3-hydroxyacyl-CoA dehydrogenase
FIU91_RS10115	COG1024	Enoyl-CoA hydratase
FIU91_RS10135	COG3360	Dodecin
FIU91_RS10145	COG0306	phosphate transporter
FIU91_RS10165	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FIU91_RS10170	COG3265	gluconokinase activity
FIU91_RS10175	COG1609	Transcriptional regulator
FIU91_RS10195	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FIU91_RS10210	COG0625	glutathione transferase activity
FIU91_RS10225	COG0352	thiamine-phosphate diphosphorylase activity
FIU91_RS10230	COG0351	phosphomethylpyrimidine kinase
FIU91_RS10275	COG1522	sequence-specific DNA binding
FIU91_RS10285	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FIU91_RS10295	COG0500	methyltransferase
FIU91_RS10300	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FIU91_RS10315	COG0719	Fe-S assembly protein
FIU91_RS10320	COG0396	ATPase activity
FIU91_RS10335	COG0393	Putative heavy-metal-binding
FIU91_RS10350	COG0719	Fe-S assembly protein
FIU91_RS10360	COG1959	2 iron, 2 sulfur cluster binding
FIU91_RS10365	COG2945	thiolester hydrolase activity
FIU91_RS10380	COG0477	Major facilitator Superfamily
FIU91_RS10385	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FIU91_RS10395	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FIU91_RS10400	COG2833	Protein of unknown function (DUF455)
FIU91_RS10405	COG0739	heme binding
FIU91_RS10415	COG0477	Major facilitator Superfamily
FIU91_RS10440	COG2814	Major facilitator Superfamily
FIU91_RS10450	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FIU91_RS10455	COG0215	cysteine-tRNA ligase activity
FIU91_RS10475	COG0105	UTP biosynthetic process
FIU91_RS10480	COG0488	(ABC) transporter
FIU91_RS10485	COG2095	MarC family integral membrane protein
FIU91_RS10500	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FIU91_RS10505	COG0795	lipopolysaccharide-transporting ATPase activity
FIU91_RS10525	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FIU91_RS10530	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FIU91_RS10540	COG2890	protein-(glutamine-N5) methyltransferase activity
FIU91_RS10545	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FIU91_RS10560	COG0010	Belongs to the arginase family
FIU91_RS10565	COG1473	amidohydrolase
FIU91_RS10570	COG3956	TIGRFAM MazG family protein
FIU91_RS10580	COG0456	acetyltransferase
FIU91_RS10595	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FIU91_RS10600	COG3038	cytochrome b561
FIU91_RS10610	COG2353	YceI-like domain
FIU91_RS10620	COG0360	Binds together with S18 to 16S ribosomal RNA
FIU91_RS10625	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FIU91_RS10630	COG0359	binds to the 23S rRNA
FIU91_RS10635	COG0737	Belongs to the 5'-nucleotidase family
FIU91_RS10640	COG0544	peptidyl-prolyl cis-trans isomerase activity
FIU91_RS10655	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FIU91_RS10655	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FIU91_RS10700	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FIU91_RS10710	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FIU91_RS10730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FIU91_RS10740	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FIU91_RS10745	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FIU91_RS10750	COG4133	protoheme IX ABC transporter activity
FIU91_RS10755	COG3737	Protein of unknown function (DUF498/DUF598)
FIU91_RS10760	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FIU91_RS10765	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FIU91_RS10770	COG1862	Preprotein translocase
FIU91_RS10780	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FIU91_RS10800	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FIU91_RS10805	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FIU91_RS10810	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FIU91_RS10825	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FIU91_RS10840	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FIU91_RS10855	COG0028	Belongs to the TPP enzyme family
FIU91_RS10860	COG0440	acetolactate synthase activity
FIU91_RS10875	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FIU91_RS10890	COG0436	Aminotransferase
FIU91_RS10915	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FIU91_RS10925	COG0156	8-amino-7-oxononanoate synthase activity
FIU91_RS10950	COG4175	Glycine betaine
FIU91_RS10970	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FIU91_RS10975	COG0248	Ppx GppA phosphatase
FIU91_RS10990	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FIU91_RS10995	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FIU91_RS11020	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FIU91_RS11025	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FIU91_RS11025	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FIU91_RS11040	COG4770	biotin carboxylase activity
FIU91_RS11060	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FIU91_RS11070	COG1396	sequence-specific DNA binding
FIU91_RS11070	COG3800	Transcriptional regulator
FIU91_RS11085	COG2873	o-acetylhomoserine
FIU91_RS11095	COG3588	fructose-bisphosphate aldolase
FIU91_RS11110	COG0785	Cytochrome C biogenesis protein
FIU91_RS11115	COG0425	Belongs to the sulfur carrier protein TusA family
FIU91_RS11120	COG1530	ribonuclease E activity
FIU91_RS11125	COG2084	Dehydrogenase
FIU91_RS11135	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FIU91_RS11140	COG1923	regulation of RNA biosynthetic process
FIU91_RS11150	COG0569	domain protein
FIU91_RS11155	COG2204	response regulator
FIU91_RS11165	COG2204	response regulator
FIU91_RS11170	COG3852	Histidine kinase
FIU91_RS11175	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FIU91_RS11185	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FIU91_RS11190	COG1546	Belongs to the CinA family
FIU91_RS11195	COG2867	negative regulation of translational initiation
FIU91_RS11200	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FIU91_RS11215	COG1028	Short-chain dehydrogenase reductase Sdr
FIU91_RS11225	COG0800	Aldolase
FIU91_RS11230	COG3734	2-keto-3-deoxy-galactonokinase
FIU91_RS11235	COG1028	Short-chain dehydrogenase reductase Sdr
FIU91_RS11240	COG0129	dihydroxy-acid dehydratase activity
FIU91_RS11245	COG1486	melibiose metabolic process
FIU91_RS11250	COG0395	ABC-type sugar transport system, permease component
FIU91_RS11255	COG1175	transmembrane transport
FIU91_RS11290	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
FIU91_RS11305	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FIU91_RS11310	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FIU91_RS11315	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FIU91_RS11320	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FIU91_RS11325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FIU91_RS11360	COG1309	transcriptional regulator
FIU91_RS11370	COG0167	dihydroorotate dehydrogenase activity
FIU91_RS11370	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FIU91_RS11375	COG0493	'glutamate synthase
FIU91_RS11415	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
FIU91_RS11425	COG3639	organic phosphonate transmembrane transporter activity
FIU91_RS11435	COG2188	Transcriptional regulator
FIU91_RS11440	COG3624	Phosphonate C-P lyase system protein PhnG
FIU91_RS11445	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
FIU91_RS11450	COG3626	phosphonate metabolism
FIU91_RS11465	COG3627	carbon phosphorus lyase activity
FIU91_RS11470	COG4107	phosphonate C-P lyase system protein PhnK
FIU91_RS11475	COG4778	phosphonate C-P lyase system protein PhnL
FIU91_RS11485	COG3454	Phosphonate metabolism
FIU91_RS11490	COG5002	protein histidine kinase activity
FIU91_RS11500	COG0745	RESPONSE REGULATOR receiver
FIU91_RS11510	COG1072	(Pantothenic acid kinase))
FIU91_RS11515	COG3246	L-lysine catabolic process to acetate
FIU91_RS11525	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FIU91_RS11550	COG1454	alcohol dehydrogenase
FIU91_RS11560	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FIU91_RS11565	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FIU91_RS11570	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FIU91_RS11575	COG2423	ornithine cyclodeaminase activity
FIU91_RS11580	COG0436	Aminotransferase
FIU91_RS11600	COG4176	ABC-type proline glycine betaine transport system permease component
FIU91_RS11605	COG4175	Glycine betaine
FIU91_RS11605	COG0517	IMP dehydrogenase activity
FIU91_RS11620	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FIU91_RS11620	COG2010	Cytochrome c
FIU91_RS11625	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FIU91_RS11630	COG2951	lytic endotransglycosylase activity
FIU91_RS11635	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FIU91_RS11645	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FIU91_RS11650	COG2333	competence protein COMEC
FIU91_RS11650	COG0658	competence protein
FIU91_RS11655	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FIU91_RS11660	COG0372	Belongs to the citrate synthase family
FIU91_RS11675	COG1024	Enoyl-CoA hydratase
FIU91_RS11680	COG3088	subunit of a heme lyase
FIU91_RS11685	COG1138	Cytochrome C-type biogenesis protein
FIU91_RS11710	COG0166	Belongs to the GPI family
FIU91_RS11720	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FIU91_RS11740	COG0516	GMP reductase activity
FIU91_RS11740	COG0517	IMP dehydrogenase activity
FIU91_RS11745	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FIU91_RS11770	COG0148	phosphopyruvate hydratase activity
FIU91_RS11785	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FIU91_RS11810	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FIU91_RS11815	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FIU91_RS11820	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FIU91_RS11830	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FIU91_RS11835	COG3743	rRNA binding
FIU91_RS11835	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FIU91_RS11850	COG0737	Belongs to the 5'-nucleotidase family
FIU91_RS11865	COG4177	L-phenylalanine transmembrane transporter activity
FIU91_RS11910	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FIU91_RS11925	COG1172	Belongs to the binding-protein-dependent transport system permease family
FIU91_RS11930	COG1172	Belongs to the binding-protein-dependent transport system permease family
FIU91_RS11935	COG1129	ABC transporter
FIU91_RS11940	COG1879	ABC-type sugar transport system periplasmic component
FIU91_RS11955	COG0129	dihydroxy-acid dehydratase activity
FIU91_RS11965	COG4214	carbohydrate transport
FIU91_RS11970	COG1129	ABC transporter
FIU91_RS11975	COG4213	ABC transporter substrate-binding protein
FIU91_RS11990	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FIU91_RS11995	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FIU91_RS11995	COG3264	Mechanosensitive ion channel
FIU91_RS12005	COG0494	nUDIX hydrolase
FIU91_RS12015	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FIU91_RS12020	COG0415	Belongs to the DNA photolyase family
FIU91_RS12030	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FIU91_RS12035	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FIU91_RS12040	COG0604	alcohol dehydrogenase
FIU91_RS12070	COG0367	asparagine synthase
FIU91_RS12080	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FIU91_RS12085	COG0363	glucosamine-6-phosphate deaminase activity
FIU91_RS12090	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FIU91_RS12095	COG0438	transferase activity, transferring glycosyl groups
FIU91_RS12095	COG0297	glycogen (starch) synthase activity
FIU91_RS12105	COG0489	protein tyrosine kinase activity
FIU91_RS12105	COG3206	protein involved in exopolysaccharide biosynthesis
FIU91_RS12115	COG0438	transferase activity, transferring glycosyl groups
FIU91_RS12135	COG2197	response regulator
FIU91_RS12140	COG1086	Polysaccharide biosynthesis protein
FIU91_RS12170	COG0438	transferase activity, transferring glycosyl groups
FIU91_RS12185	COG0114	fumarate hydratase activity
FIU91_RS12215	COG1522	sequence-specific DNA binding
FIU91_RS12225	COG1329	Transcriptional regulator
FIU91_RS12230	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FIU91_RS12235	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FIU91_RS12255	COG2267	carboxylic ester hydrolase activity
FIU91_RS12265	COG1793	dna ligase
FIU91_RS12280	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FIU91_RS12285	COG0386	Belongs to the glutathione peroxidase family
FIU91_RS12305	COG3119	arylsulfatase activity
FIU91_RS12325	COG0217	transcriptional regulatory protein
FIU91_RS12330	COG3920	Histidine kinase
FIU91_RS12335	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FIU91_RS12340	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FIU91_RS12355	COG4172	Belongs to the ABC transporter superfamily
FIU91_RS12365	COG0601	transmembrane transport
FIU91_RS12370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIU91_RS12380	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FIU91_RS12395	COG1028	Short-chain dehydrogenase reductase Sdr
FIU91_RS12420	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FIU91_RS12425	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FIU91_RS12450	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FIU91_RS12475	COG1519	Transferase
FIU91_RS12480	COG0438	transferase activity, transferring glycosyl groups
FIU91_RS12550	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FIU91_RS12560	COG0321	lipoyl(octanoyl) transferase activity
FIU91_RS12570	COG0366	Alpha amylase catalytic
FIU91_RS12590	COG1610	YqeY-like protein
FIU91_RS12595	COG0505	Belongs to the CarA family
FIU91_RS12605	COG1802	Transcriptional regulator
FIU91_RS12615	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FIU91_RS12620	COG5425	PFAM Usg family protein
FIU91_RS12625	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FIU91_RS12635	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FIU91_RS12640	COG1612	heme a metabolic process
FIU91_RS12650	COG0352	thiamine-phosphate diphosphorylase activity
FIU91_RS12655	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FIU91_RS12660	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FIU91_RS12685	COG1024	Enoyl-CoA hydratase
FIU91_RS12690	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FIU91_RS12700	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FIU91_RS12705	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FIU91_RS12715	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FIU91_RS12720	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FIU91_RS12735	COG0482	sulfurtransferase activity
FIU91_RS12740	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FIU91_RS12750	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FIU91_RS12765	COG0275	rRNA processing
FIU91_RS12770	COG2001	Belongs to the MraZ family
FIU91_RS12780	COG0525	valine-tRNA ligase activity
FIU91_RS12790	COG4251	negative regulation of phosphorylation
FIU91_RS12920	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FIU91_RS12930	COG2050	protein possibly involved in aromatic compounds catabolism
FIU91_RS12935	COG1271	oxidase subunit
FIU91_RS12940	COG1294	oxidase, subunit
FIU91_RS12955	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FIU91_RS12960	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FIU91_RS12975	COG1217	gtp-binding protein TYPA
FIU91_RS12990	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FIU91_RS12995	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FIU91_RS13000	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FIU91_RS13005	COG1121	(ABC) transporter
FIU91_RS13020	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FIU91_RS13060	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FIU91_RS13070	COG0438	transferase activity, transferring glycosyl groups
FIU91_RS13075	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FIU91_RS13080	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FIU91_RS13080	COG1116	anion transmembrane transporter activity
FIU91_RS13085	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FIU91_RS13110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIU91_RS13115	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIU91_RS13120	COG3976	FMN-binding domain protein
FIU91_RS13120	COG1053	succinate dehydrogenase
FIU91_RS13150	COG2188	Transcriptional regulator
FIU91_RS13155	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FIU91_RS13165	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FIU91_RS13180	COG0012	GTP binding
FIU91_RS13185	COG0534	Mate efflux family protein
FIU91_RS13190	COG2326	polyphosphate kinase activity
FIU91_RS13200	COG0159	tryptophan synthase activity
FIU91_RS13205	COG1252	NADH dehydrogenase
FIU91_RS13210	COG0133	tryptophan synthase activity
FIU91_RS13240	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FIU91_RS13245	COG0738	Major facilitator superfamily
FIU91_RS13250	COG1304	FMN binding
FIU91_RS13255	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FIU91_RS13275	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FIU91_RS13280	COG0318	PFAM AMP-dependent synthetase and ligase
FIU91_RS13310	COG5002	protein histidine kinase activity
FIU91_RS13350	COG0410	ABC transporter
FIU91_RS13355	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FIU91_RS13370	COG0439	Biotin carboxylase
FIU91_RS13375	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FIU91_RS13400	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FIU91_RS13405	COG0740	serine-type endopeptidase activity
FIU91_RS13445	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FIU91_RS13445	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FIU91_RS13450	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FIU91_RS13455	COG0432	Pfam Uncharacterised protein family UPF0047
FIU91_RS13465	COG4221	oxidoreductase activity
FIU91_RS13475	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FIU91_RS13480	COG0358	DNA primase activity
FIU91_RS13490	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FIU91_RS13530	COG0534	Mate efflux family protein
FIU91_RS13555	COG1960	acyl-CoA dehydrogenase activity
FIU91_RS13565	COG0625	glutathione transferase activity
FIU91_RS13570	COG0183	Belongs to the thiolase family
FIU91_RS13580	COG1250	3-hydroxyacyl-CoA dehydrogenase
FIU91_RS13580	COG1024	Enoyl-CoA hydratase
FIU91_RS13585	COG1570	exodeoxyribonuclease VII activity
FIU91_RS13590	COG0151	Belongs to the GarS family
FIU91_RS13620	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FIU91_RS13630	COG1522	sequence-specific DNA binding
FIU91_RS13635	COG0686	Belongs to the AlaDH PNT family
FIU91_RS13655	COG0469	pyruvate kinase activity
FIU91_RS13665	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FIU91_RS13670	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FIU91_RS13685	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FIU91_RS13695	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FIU91_RS13695	COG0072	phenylalanine-tRNA ligase activity
FIU91_RS13705	COG1970	mechanosensitive ion channel activity
FIU91_RS13710	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FIU91_RS13725	COG0587	DNA-directed DNA polymerase activity
FIU91_RS13745	COG0330	HflC and HflK could
FIU91_RS13760	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FIU91_RS13765	COG1760	l-serine dehydratase
FIU91_RS13770	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FIU91_RS13775	COG0022	dehydrogenase e1 component
FIU91_RS13775	COG0508	dehydrogenase complex catalyzes the overall conversion of
FIU91_RS13785	COG0508	dehydrogenase complex catalyzes the overall conversion of
FIU91_RS13795	COG1045	serine acetyltransferase
FIU91_RS13800	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FIU91_RS13875	COG4695	Portal protein
FIU91_RS13890	COG3273	potassium ion transport
FIU91_RS13890	COG0471	metal ion transport
FIU91_RS13900	COG1304	FMN binding
FIU91_RS13905	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FIU91_RS13935	COG0131	Imidazoleglycerol-phosphate dehydratase
FIU91_RS13940	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FIU91_RS13950	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FIU91_RS13960	COG0107	imidazoleglycerol-phosphate synthase activity
FIU91_RS13970	COG2135	peptidase activity
FIU91_RS13990	COG0135	phosphoribosylanthranilate isomerase activity
FIU91_RS14000	COG0776	regulation of translation
FIU91_RS14005	COG0539	negative regulation of cytoplasmic translation
FIU91_RS14020	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FIU91_RS14030	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FIU91_RS14035	COG1007	ATP synthesis coupled electron transport
FIU91_RS14050	COG0713	ATP synthesis coupled electron transport
FIU91_RS14065	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FIU91_RS14070	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FIU91_RS14120	COG0649	NAD binding
FIU91_RS14125	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FIU91_RS14130	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FIU91_RS14140	COG1024	Enoyl-CoA hydratase
FIU91_RS14160	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FIU91_RS14165	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FIU91_RS14175	COG1960	acyl-CoA dehydrogenase activity
FIU91_RS14195	COG0546	phosphoglycolate phosphatase activity
FIU91_RS14200	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FIU91_RS14215	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FIU91_RS14230	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FIU91_RS14235	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FIU91_RS14250	COG3920	Histidine kinase
FIU91_RS14255	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FIU91_RS14260	COG1754	DNA topoisomerase type I activity
FIU91_RS14260	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FIU91_RS14265	COG0758	DNA mediated transformation
FIU91_RS14270	COG0312	modulator of DNA gyrase
FIU91_RS14280	COG0109	protoheme IX farnesyltransferase activity
FIU91_RS14290	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FIU91_RS14300	COG3346	SURF1 family
FIU91_RS14310	COG0612	Peptidase, M16
FIU91_RS14350	COG4964	Belongs to the GSP D family
FIU91_RS14355	COG2885	chlorophyll binding
FIU91_RS14420	COG0438	transferase activity, transferring glycosyl groups
FIU91_RS14445	COG0180	Tryptophanyl-tRNA synthetase
FIU91_RS14450	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FIU91_RS14455	COG2514	catechol 2,3-dioxygenase activity
FIU91_RS14470	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FIU91_RS14475	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FIU91_RS14480	COG1214	PFAM Peptidase M22, glycoprotease
FIU91_RS14490	COG1744	ABC transporter substrate-binding protein PnrA-like
FIU91_RS14495	COG3845	ABC transporter
FIU91_RS14505	COG4603	Belongs to the binding-protein-dependent transport system permease family
FIU91_RS14510	COG1079	Belongs to the binding-protein-dependent transport system permease family
FIU91_RS14515	COG0730	response to heat
FIU91_RS14530	COG0322	excinuclease ABC activity
FIU91_RS14575	COG1183	phosphatidylcholine synthase activity
FIU91_RS14590	COG4974	Belongs to the 'phage' integrase family
FIU91_RS14600	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FIU91_RS14615	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FIU91_RS14620	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FIU91_RS14630	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FIU91_RS14635	COG0804	urea catabolic process
FIU91_RS14660	COG0832	Belongs to the urease beta subunit family
FIU91_RS14670	COG0831	urea catabolic process
FIU91_RS14675	COG0829	nickel cation binding
FIU91_RS14680	COG1720	tRNA m6t6A37 methyltransferase activity
FIU91_RS14700	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FIU91_RS14705	COG0281	malic enzyme
FIU91_RS14705	COG0280	phosphate acetyltransferase
FIU91_RS14715	COG0295	cytidine deaminase activity
FIU91_RS14720	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FIU91_RS14725	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FIU91_RS14730	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FIU91_RS14735	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FIU91_RS14785	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FIU91_RS14795	COG0019	diaminopimelate decarboxylase activity
FIU91_RS14800	COG1473	amidohydrolase
FIU91_RS14805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIU91_RS14810	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FIU91_RS14815	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FIU91_RS14820	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FIU91_RS14840	COG0126	phosphoglycerate kinase activity
FIU91_RS14865	COG3750	Belongs to the UPF0335 family
FIU91_RS14875	COG1132	(ABC) transporter
FIU91_RS14895	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FIU91_RS14900	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FIU91_RS14915	COG0596	Alpha beta hydrolase
FIU91_RS14925	COG1254	Belongs to the acylphosphatase family
FIU91_RS14930	COG2080	2 iron, 2 sulfur cluster binding
FIU91_RS14935	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FIU91_RS14940	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FIU91_RS14945	COG0481	GTPase activity
FIU91_RS14960	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FIU91_RS14965	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FIU91_RS14985	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FIU91_RS14990	COG1703	isobutyryl-CoA mutase activity
FIU91_RS14995	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FIU91_RS15000	COG0756	dUTP diphosphatase activity
FIU91_RS15005	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FIU91_RS15020	COG0606	chelatase, subunit chli
FIU91_RS15035	COG0792	nuclease activity
FIU91_RS15040	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FIU91_RS15050	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FIU91_RS15060	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FIU91_RS15070	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FIU91_RS15075	COG0154	amidase activity
FIU91_RS15090	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FIU91_RS15100	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIU91_RS15105	COG1832	CoA-binding protein
FIU91_RS15125	COG2917	probably involved in intracellular septation
FIU91_RS15140	COG0552	protein localization to endoplasmic reticulum
FIU91_RS15145	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FIU91_RS15175	COG2017	converts alpha-aldose to the beta-anomer
FIU91_RS15180	COG0277	FAD linked oxidase domain protein
FIU91_RS15210	COG0300	oxidoreductase activity
FIU91_RS15215	COG4221	oxidoreductase activity
FIU91_RS15255	COG1028	Short-chain dehydrogenase reductase Sdr
FIU91_RS15255	COG0604	alcohol dehydrogenase
FIU91_RS15255	COG3321	synthase
FIU91_RS15260	COG1028	Short-chain dehydrogenase reductase Sdr
FIU91_RS15260	COG0604	alcohol dehydrogenase
FIU91_RS15260	COG3321	synthase
FIU91_RS15290	COG3002	Belongs to the UPF0753 family
FIU91_RS15295	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FIU91_RS15305	COG1741	Belongs to the pirin family
FIU91_RS15310	COG3474	cytochrome
FIU91_RS15320	COG1175	transmembrane transport
FIU91_RS15325	COG0395	ABC-type sugar transport system, permease component
FIU91_RS15330	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FIU91_RS15335	COG0156	8-amino-7-oxononanoate synthase activity
FIU91_RS15345	COG0446	pyridine nucleotide-disulphide oxidoreductase
FIU91_RS15360	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FIU91_RS15365	COG0737	Belongs to the 5'-nucleotidase family
FIU91_RS15370	COG3258	Cytochrome c
FIU91_RS15395	COG0785	Cytochrome C biogenesis protein
FIU91_RS15405	COG0640	Transcriptional regulator
FIU91_RS15410	COG2391	methyltransferase activity
FIU91_RS15415	COG2358	TRAP transporter, solute receptor (TAXI family
FIU91_RS15430	COG4191	Histidine kinase
FIU91_RS15460	COG5002	protein histidine kinase activity
FIU91_RS15475	COG0246	Mannitol dehydrogenase
FIU91_RS15480	COG1501	Belongs to the glycosyl hydrolase 31 family
FIU91_RS15490	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FIU91_RS15500	COG3250	beta-galactosidase activity
FIU91_RS15505	COG2186	Transcriptional regulator
FIU91_RS15510	COG1312	Catalyzes the dehydration of D-mannonate
FIU91_RS15515	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIU91_RS15545	COG2205	protein histidine kinase activity
FIU91_RS15570	COG3180	Ammonia monooxygenase
FIU91_RS15595	COG2072	flavoprotein involved in K transport
FIU91_RS15600	COG0385	Bile acid
FIU91_RS15610	COG1028	Short-chain dehydrogenase reductase Sdr
FIU91_RS15625	COG5564	TIM-barrel signal transduction protein
FIU91_RS15630	COG5441	Belongs to the UPF0261 family
FIU91_RS15665	COG5564	TIM-barrel signal transduction protein
FIU91_RS15665	COG2204	response regulator
FIU91_RS15675	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FIU91_RS15680	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FIU91_RS15680	COG1082	Xylose isomerase domain protein TIM barrel
FIU91_RS15685	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FIU91_RS15695	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIU91_RS15700	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FIU91_RS15725	COG0546	phosphoglycolate phosphatase activity
FIU91_RS15735	COG3706	GGDEF domain
FIU91_RS15770	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FIU91_RS15775	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FIU91_RS15780	COG1253	flavin adenine dinucleotide binding
FIU91_RS15785	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FIU91_RS15790	COG1702	phosphate starvation-inducible protein PhoH
FIU91_RS15805	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FIU91_RS15825	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FIU91_RS15830	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FIU91_RS15835	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FIU91_RS15845	COG2205	protein histidine kinase activity
FIU91_RS15845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FIU91_RS15860	COG1522	sequence-specific DNA binding
FIU91_RS15880	COG0483	inositol monophosphate 1-phosphatase activity
FIU91_RS15900	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
FIU91_RS15925	COG1846	Transcriptional regulator
FIU91_RS15930	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FIU91_RS15950	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FIU91_RS15955	COG0085	RNA polymerase activity
FIU91_RS15960	COG0222	ribosome binding
FIU91_RS15965	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FIU91_RS15980	COG0081	regulation of translation
FIU91_RS15985	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FIU91_RS15995	COG0250	Participates in transcription elongation, termination and antitermination
FIU91_RS16000	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FIU91_RS16020	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FIU91_RS16025	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FIU91_RS16045	COG0300	oxidoreductase activity
FIU91_RS16055	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FIU91_RS16085	COG1250	3-hydroxyacyl-CoA dehydrogenase
FIU91_RS16095	COG4106	trans-aconitate 2-methyltransferase activity
FIU91_RS16100	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FIU91_RS16105	COG0037	tRNA processing
FIU91_RS16115	COG2885	chlorophyll binding
FIU91_RS16120	COG0823	Involved in the tonB-independent uptake of proteins
FIU91_RS16130	COG0848	biopolymer transport protein
FIU91_RS16140	COG0824	Thioesterase
FIU91_RS16150	COG2255	four-way junction helicase activity
FIU91_RS16155	COG0632	four-way junction helicase activity
FIU91_RS16160	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FIU91_RS16175	COG2264	protein methyltransferase activity
FIU91_RS16190	COG2391	methyltransferase activity
FIU91_RS16195	COG0662	Cupin 2, conserved barrel domain protein
FIU91_RS16200	COG0842	Transport permease protein
FIU91_RS16205	COG1131	(ABC) transporter
FIU91_RS16210	COG0697	spore germination
FIU91_RS16215	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FIU91_RS16220	COG0181	hydroxymethylbilane synthase activity
FIU91_RS16230	COG2816	NAD+ diphosphatase activity
FIU91_RS16235	COG0737	Belongs to the 5'-nucleotidase family
FIU91_RS16255	COG0077	Prephenate dehydratase
FIU91_RS16255	COG1605	Chorismate mutase
FIU91_RS16260	COG3474	cytochrome
FIU91_RS16270	COG4166	transmembrane transport
FIU91_RS16275	COG4174	ABC transporter (Permease)
FIU91_RS16280	COG4239	(ABC) transporter, permease
FIU91_RS16285	COG4172	Belongs to the ABC transporter superfamily
FIU91_RS16290	COG0583	DNA-binding transcription factor activity
FIU91_RS16295	COG1686	Belongs to the peptidase S11 family
FIU91_RS16305	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FIU91_RS16320	COG0408	coproporphyrinogen oxidase activity
FIU91_RS16330	COG0590	tRNA wobble adenosine to inosine editing
FIU91_RS16335	COG1187	pseudouridine synthase activity
FIU91_RS16355	COG3853	Toxic anion resistance protein (TelA)
FIU91_RS16380	COG1490	D-aminoacyl-tRNA deacylase activity
FIU91_RS16385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIU91_RS16405	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FIU91_RS16425	COG0745	RESPONSE REGULATOR receiver
FIU91_RS16430	COG2198	Histidine kinase
FIU91_RS16430	COG0643	Histidine kinase
FIU91_RS16440	COG0840	transmembrane signaling receptor activity
FIU91_RS16450	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FIU91_RS16455	COG2201	protein-glutamate methylesterase activity
FIU91_RS16510	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FIU91_RS16515	COG1204	response to ionizing radiation
FIU91_RS16545	COG5002	protein histidine kinase activity
FIU91_RS16545	COG3850	Histidine kinase
FIU91_RS16550	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FIU91_RS16560	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FIU91_RS16565	COG0594	ribonuclease P activity
FIU91_RS16570	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FIU91_RS16580	COG2032	superoxide dismutase activity
FIU91_RS16585	COG0037	tRNA processing
FIU91_RS16590	COG5001	Diguanylate cyclase
FIU91_RS16590	COG3300	MHYT domain
FIU91_RS16595	COG0706	membrane insertase activity
FIU91_RS16605	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FIU91_RS16610	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FIU91_RS16620	COG1126	abc transporter atp-binding protein
FIU91_RS16625	COG0765	amino acid transport
FIU91_RS16630	COG4597	amino acid ABC transporter
FIU91_RS16635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FIU91_RS16650	COG0564	pseudouridine synthase activity
FIU91_RS16660	COG2132	Multicopper oxidase
FIU91_RS16665	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FIU91_RS16675	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FIU91_RS16680	COG0776	regulation of translation
FIU91_RS16685	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FIU91_RS16715	COG1012	belongs to the aldehyde dehydrogenase family
FIU91_RS16720	COG0779	Required for maturation of 30S ribosomal subunits
FIU91_RS16735	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FIU91_RS16740	COG0494	nUDIX hydrolase
FIU91_RS16745	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FIU91_RS16750	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FIU91_RS16755	COG0653	protein targeting
FIU91_RS16770	COG2003	Belongs to the UPF0758 family
FIU91_RS16780	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FIU91_RS16790	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FIU91_RS16800	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FIU91_RS16810	COG0512	Glutamine amidotransferase of anthranilate synthase
FIU91_RS16810	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FIU91_RS16830	COG1968	undecaprenyl-diphosphatase activity
FIU91_RS16840	COG0587	DNA-directed DNA polymerase activity
FIU91_RS16850	COG1960	acyl-CoA dehydrogenase activity
FIU91_RS16860	COG0318	PFAM AMP-dependent synthetase and ligase
FIU91_RS16865	COG2130	NADP-dependent
FIU91_RS16880	COG0604	alcohol dehydrogenase
FIU91_RS16885	COG2937	Belongs to the GPAT DAPAT family
FIU91_RS16890	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FIU91_RS16890	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FIU91_RS16900	COG0813	purine-nucleoside phosphorylase activity
FIU91_RS16945	COG2030	dehydratase
FIU91_RS16970	COG0039	L-malate dehydrogenase activity
FIU91_RS16985	COG0045	succinate-CoA ligase (ADP-forming) activity
FIU91_RS17005	COG0567	Dehydrogenase, E1 component
FIU91_RS17010	COG0508	dehydrogenase complex catalyzes the overall conversion of
FIU91_RS17030	COG0778	Nitroreductase
FIU91_RS17055	COG2884	Cell division ATP-binding protein ftsE
FIU91_RS17090	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FIU91_RS17110	COG1403	HNH endonuclease
FIU91_RS17120	COG0625	glutathione transferase activity
FIU91_RS17135	COG0495	leucyl-tRNA aminoacylation
FIU91_RS17140	COG0438	transferase activity, transferring glycosyl groups
FIU91_RS17155	COG0457	Tetratricopeptide repeat
FIU91_RS17160	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FIU91_RS17165	COG1227	inorganic diphosphatase activity
FIU91_RS17175	COG2030	dehydratase
FIU91_RS17180	COG0196	riboflavin kinase activity
FIU91_RS17185	COG2983	Belongs to the UPF0260 family
FIU91_RS17205	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FIU91_RS17220	COG0436	Aminotransferase
FIU91_RS17225	COG0154	amidase activity
FIU91_RS17230	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FIU91_RS17235	COG1196	nuclear chromosome segregation
FIU91_RS17235	COG0739	heme binding
FIU91_RS17235	COG0741	lytic transglycosylase activity
FIU91_RS17245	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FIU91_RS17250	COG0142	geranyltranstransferase activity
FIU91_RS17255	COG1722	exodeoxyribonuclease VII activity
FIU91_RS17260	COG0123	including yeast histone deacetylase and acetoin utilization protein
FIU91_RS17270	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FIU91_RS17275	COG1115	amino acid carrier protein
FIU91_RS17285	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FIU91_RS17290	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FIU91_RS17295	COG3830	Belongs to the UPF0237 family
FIU91_RS17295	COG0560	Phosphoserine phosphatase
FIU91_RS17310	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FIU91_RS17325	COG0583	DNA-binding transcription factor activity
FIU91_RS17330	COG0693	protein deglycase activity
FIU91_RS17335	COG0328	RNA-DNA hybrid ribonuclease activity
FIU91_RS17350	COG3901	Regulator of nitric oxide reductase transcription
FIU91_RS17350	COG0348	domain, Protein
FIU91_RS17355	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FIU91_RS17355	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FIU91_RS17360	COG5508	conserved small protein
FIU91_RS17370	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FIU91_RS17375	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FIU91_RS17385	COG0312	modulator of DNA gyrase
FIU91_RS17400	COG1519	Transferase
FIU91_RS17420	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FIU91_RS17425	COG3409	Peptidoglycan-binding domain 1 protein
FIU91_RS17425	COG0793	Belongs to the peptidase S41A family
FIU91_RS17485	COG3383	formate dehydrogenase (NAD+) activity
FIU91_RS17505	COG0791	NLP P60 protein
FIU91_RS17510	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FIU91_RS17520	COG0288	reversible hydration of carbon dioxide
FIU91_RS17535	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FIU91_RS17545	COG2171	N-acyltransferase activity
FIU91_RS17575	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FIU91_RS17590	COG2951	lytic endotransglycosylase activity
FIU91_RS17600	COG1051	belongs to the nudix hydrolase family
FIU91_RS17605	COG0793	Belongs to the peptidase S41A family
FIU91_RS17615	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FIU91_RS17630	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FIU91_RS17640	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FIU91_RS17645	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FIU91_RS17685	COG0778	Nitroreductase
FIU91_RS17700	COG0346	lactoylglutathione lyase activity
FIU91_RS17715	COG0697	spore germination
FIU91_RS17720	COG0473	3-isopropylmalate dehydrogenase activity
FIU91_RS17735	COG0066	3-isopropylmalate dehydratase activity
FIU91_RS17740	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FIU91_RS17745	COG3264	Mechanosensitive ion channel
FIU91_RS17745	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FIU91_RS17755	COG0183	Belongs to the thiolase family
FIU91_RS17765	COG3022	response to hydroperoxide
FIU91_RS17770	COG0514	ATP-dependent DNA helicase (RecQ)
FIU91_RS17790	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FIU91_RS17800	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FIU91_RS17815	COG0019	diaminopimelate decarboxylase activity
FIU91_RS17835	COG0165	Argininosuccinate lyase
FIU91_RS17840	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FIU91_RS17865	COG0287	Prephenate dehydrogenase
FIU91_RS17870	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FIU91_RS17875	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FIU91_RS17880	COG1335	isochorismatase
FIU91_RS17885	COG1054	Belongs to the UPF0176 family
FIU91_RS17890	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FIU91_RS17895	COG1999	signal sequence binding
FIU91_RS17910	COG0802	atpase or kinase
FIU91_RS17915	COG3178	'Phosphotransferase
FIU91_RS17920	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FIU91_RS17925	COG2887	Belongs to the helicase family. UvrD subfamily
FIU91_RS17930	COG1074	ATP-dependent DNA helicase activity
FIU91_RS17945	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FIU91_RS17950	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FIU91_RS17975	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FIU91_RS17980	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FIU91_RS17985	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FIU91_RS18015	COG3034	peptidoglycan biosynthetic process
FIU91_RS18025	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FIU91_RS18030	COG1132	(ABC) transporter
FIU91_RS18035	COG1132	(ABC) transporter
FIU91_RS18040	COG0617	tRNA 3'-terminal CCA addition
FIU91_RS18045	COG0494	nUDIX hydrolase
FIU91_RS18050	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FIU91_RS18055	COG0494	nUDIX hydrolase
FIU91_RS18070	COG0300	oxidoreductase activity
FIU91_RS18075	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FIU91_RS18085	COG0137	argininosuccinate synthase activity
FIU91_RS18110	COG1766	The M ring may be actively involved in energy transduction
FIU91_RS18120	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FIU91_RS18120	COG1776	CheC inhibitor of MCP methylation
FIU91_RS18125	COG1338	Plays a role in the flagellum-specific transport system
FIU91_RS18135	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FIU91_RS18140	COG1012	belongs to the aldehyde dehydrogenase family
FIU91_RS18145	COG1522	sequence-specific DNA binding
FIU91_RS18155	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FIU91_RS18160	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FIU91_RS18185	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FIU91_RS18210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FIU91_RS18215	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FIU91_RS18215	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FIU91_RS18220	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FIU91_RS18220	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FIU91_RS18225	COG0281	malic enzyme
FIU91_RS18225	COG0280	phosphate acetyltransferase
FIU91_RS18230	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FIU91_RS18235	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FIU91_RS18240	COG1420	regulation of RNA biosynthetic process
FIU91_RS18245	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FIU91_RS18250	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FIU91_RS18255	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FIU91_RS18270	COG0357	Ribosomal RNA small subunit methyltransferase G
FIU91_RS18275	COG0445	tRNA wobble uridine modification
FIU91_RS18280	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FIU91_RS18285	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FIU91_RS18290	COG0424	maF-like protein
FIU91_RS18300	COG0237	dephospho-CoA kinase activity
FIU91_RS18305	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FIU91_RS18310	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FIU91_RS18345	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
FIU91_RS18350	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
FIU91_RS18360	COG1233	COG1233 Phytoene dehydrogenase and related
FIU91_RS18365	COG1562	ergosterol biosynthetic process
FIU91_RS18370	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FIU91_RS18375	COG5621	secreted hydrolase
FIU91_RS18380	COG1233	COG1233 Phytoene dehydrogenase and related
FIU91_RS18385	COG0142	geranyltranstransferase activity
FIU91_RS18390	COG0500	methyltransferase
FIU91_RS18395	COG1063	alcohol dehydrogenase
FIU91_RS18400	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
FIU91_RS18405	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FIU91_RS18410	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FIU91_RS18445	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FIU91_RS18455	COG0644	oxidoreductase
FIU91_RS18460	COG2211	Major facilitator Superfamily
FIU91_RS18465	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FIU91_RS18485	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FIU91_RS18490	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FIU91_RS18495	COG1429	ligase activity, forming nitrogen-metal bonds
FIU91_RS18500	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
FIU91_RS18535	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
FIU91_RS18545	COG0156	8-amino-7-oxononanoate synthase activity
FIU91_RS18560	COG4786	Flagellar basal body rod
FIU91_RS18570	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FIU91_RS18580	COG2226	methyltransferase
FIU91_RS18585	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FIU91_RS18590	COG1024	Enoyl-CoA hydratase
FIU91_RS18595	COG0268	Binds directly to 16S ribosomal RNA
FIU91_RS18600	COG1192	Involved in chromosome partitioning
FIU91_RS18610	COG0640	Transcriptional regulator
FIU91_RS18725	COG3443	Belongs to the bacterial solute-binding protein 9 family
FIU91_RS18740	COG5002	protein histidine kinase activity
FIU91_RS18800	COG0346	lactoylglutathione lyase activity
FIU91_RS18855	COG1196	nuclear chromosome segregation
FIU91_RS18855	COG0739	heme binding
FIU91_RS18855	COG0741	lytic transglycosylase activity
FIU91_RS18875	COG1196	nuclear chromosome segregation
FIU91_RS18875	COG0741	lytic transglycosylase activity
FIU91_RS18875	COG0739	heme binding
FIU91_RS18970	COG1196	nuclear chromosome segregation
FIU91_RS18970	COG0741	lytic transglycosylase activity
FIU91_RS18970	COG0739	heme binding
FIU91_RS18980	COG3451	type IV secretory pathway VirB4
FIU91_RS18995	COG1196	nuclear chromosome segregation
FIU91_RS18995	COG0739	heme binding
FIU91_RS18995	COG0741	lytic transglycosylase activity
FIU91_RS19020	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FIU91_RS19035	COG0167	dihydroorotate dehydrogenase activity
FIU91_RS19050	COG1802	Transcriptional regulator
FIU91_RS19055	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FIU91_RS19060	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FIU91_RS19070	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FIU91_RS19070	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIU91_RS19095	COG1473	amidohydrolase
FIU91_RS19160	COG1192	Involved in chromosome partitioning
FIU91_RS19185	COG4227	nucleotidyltransferase activity
FIU91_RS19225	COG3505	Type IV secretory pathway VirD4
FIU91_RS19245	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FIU91_RS19255	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
FIU91_RS19270	COG3736	Type IV secretory pathway, component VirB8