locus-tag	class	description
EI983_RS00025	COG2197	response regulator
EI983_RS00105	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EI983_RS00110	COG1459	type II secretion system
EI983_RS00125	COG1215	transferase activity, transferring glycosyl groups
EI983_RS00130	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EI983_RS00130	COG0463	Glycosyl transferase, family 2
EI983_RS00140	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EI983_RS00150	COG1091	dTDP-4-dehydrorhamnose reductase activity
EI983_RS00240	COG1192	Involved in chromosome partitioning
EI983_RS00295	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EI983_RS00310	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EI983_RS00315	COG0306	phosphate transporter
EI983_RS00320	COG3541	Predicted nucleotidyltransferase
EI983_RS00340	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EI983_RS00375	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EI983_RS00380	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EI983_RS00385	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EI983_RS00395	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EI983_RS00405	COG1970	mechanosensitive ion channel activity
EI983_RS00435	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EI983_RS00435	COG0072	phenylalanine-tRNA ligase activity
EI983_RS00455	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EI983_RS00475	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EI983_RS00480	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EI983_RS00490	COG0469	pyruvate kinase activity
EI983_RS00510	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EI983_RS00540	COG0583	DNA-binding transcription factor activity
EI983_RS00550	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EI983_RS00565	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EI983_RS00585	COG4766	ethanolamine catabolic process
EI983_RS00605	COG0686	Belongs to the AlaDH PNT family
EI983_RS00625	COG1185	polyribonucleotide nucleotidyltransferase activity
EI983_RS00630	COG2986	histidine ammonia-lyase
EI983_RS00640	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EI983_RS00650	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
EI983_RS00655	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EI983_RS00660	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EI983_RS00665	COG1960	acyl-CoA dehydrogenase activity
EI983_RS00670	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EI983_RS00680	COG2986	histidine ammonia-lyase
EI983_RS00685	COG1228	amidohydrolase
EI983_RS00695	COG2226	methyltransferase
EI983_RS00705	COG4948	Mandelate Racemase Muconate Lactonizing
EI983_RS00720	COG2301	Belongs to the HpcH HpaI aldolase family
EI983_RS00740	COG4589	Belongs to the CDS family
EI983_RS00755	COG2885	chlorophyll binding
EI983_RS00765	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EI983_RS00770	COG0009	L-threonylcarbamoyladenylate synthase
EI983_RS00775	COG1960	acyl-CoA dehydrogenase activity
EI983_RS00800	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EI983_RS00810	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EI983_RS00815	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EI983_RS00850	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EI983_RS00855	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EI983_RS00870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EI983_RS00910	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EI983_RS00910	COG0517	IMP dehydrogenase activity
EI983_RS00915	COG1054	Belongs to the UPF0176 family
EI983_RS00925	COG1335	isochorismatase
EI983_RS00930	COG3228	Belongs to the MtfA family
EI983_RS00935	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EI983_RS00950	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EI983_RS00960	COG0746	molybdenum cofactor guanylyltransferase activity
EI983_RS00965	COG1763	Mo-molybdopterin cofactor biosynthetic process
EI983_RS00970	COG0303	'Molybdopterin
EI983_RS00975	COG3806	Anti-sigma factor
EI983_RS00980	COG1595	DNA-templated transcription, initiation
EI983_RS01005	COG4221	oxidoreductase activity
EI983_RS01035	COG0625	glutathione transferase activity
EI983_RS01045	COG3383	formate dehydrogenase (NAD+) activity
EI983_RS01050	COG4638	Rieske (2fe-2S)
EI983_RS01060	COG3852	Histidine kinase
EI983_RS01085	COG0559	Belongs to the binding-protein-dependent transport system permease family
EI983_RS01115	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
EI983_RS01120	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EI983_RS01130	COG2188	Transcriptional regulator
EI983_RS01135	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EI983_RS01150	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EI983_RS01160	COG0284	orotidine-5'-phosphate decarboxylase activity
EI983_RS01200	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EI983_RS01205	COG0069	glutamate synthase activity
EI983_RS01210	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EI983_RS01215	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EI983_RS01220	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
EI983_RS01255	COG0187	DNA topoisomerase II activity
EI983_RS01270	COG2010	Cytochrome c
EI983_RS01275	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
EI983_RS01335	COG3005	denitrification pathway
EI983_RS01345	COG0348	domain, Protein
EI983_RS01350	COG0437	4 iron, 4 sulfur cluster binding
EI983_RS01355	COG0243	molybdopterin cofactor binding
EI983_RS01370	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EI983_RS01375	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EI983_RS01385	COG0626	cystathionine gamma-synthase activity
EI983_RS01420	COG1115	amino acid carrier protein
EI983_RS01455	COG2205	protein histidine kinase activity
EI983_RS01460	COG0745	RESPONSE REGULATOR receiver
EI983_RS01475	COG1902	pentaerythritol trinitrate reductase activity
EI983_RS01475	COG0446	pyridine nucleotide-disulphide oxidoreductase
EI983_RS01505	COG1309	transcriptional regulator
EI983_RS01510	COG3842	ATPase activity
EI983_RS01515	COG1177	transmembrane transport
EI983_RS01520	COG1176	ABC-type spermidine putrescine transport system, permease component I
EI983_RS01560	COG4977	sequence-specific DNA binding
EI983_RS01570	COG0446	pyridine nucleotide-disulphide oxidoreductase
EI983_RS01570	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EI983_RS01575	COG4311	Sarcosine oxidase, delta subunit
EI983_RS01580	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EI983_RS01585	COG4977	sequence-specific DNA binding
EI983_RS01610	COG2864	formate dehydrogenase
EI983_RS01615	COG0437	4 iron, 4 sulfur cluster binding
EI983_RS01620	COG3383	formate dehydrogenase (NAD+) activity
EI983_RS01620	COG0243	molybdopterin cofactor binding
EI983_RS01670	COG0489	protein tyrosine kinase activity
EI983_RS01685	COG0519	Catalyzes the synthesis of GMP from XMP
EI983_RS01685	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EI983_RS01700	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EI983_RS01710	COG0069	glutamate synthase activity
EI983_RS01735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EI983_RS01740	COG0028	Belongs to the TPP enzyme family
EI983_RS01750	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EI983_RS01755	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EI983_RS01760	COG0181	hydroxymethylbilane synthase activity
EI983_RS01765	COG0277	FAD linked oxidase domain protein
EI983_RS01775	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EI983_RS01785	COG0439	Biotin carboxylase
EI983_RS01795	COG1984	allophanate hydrolase subunit 2
EI983_RS01815	COG0145	ligase activity
EI983_RS01855	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EI983_RS01865	COG3842	ATPase activity
EI983_RS01870	COG1176	ABC-type spermidine putrescine transport system, permease component I
EI983_RS01890	COG1028	Short-chain dehydrogenase reductase Sdr
EI983_RS01895	COG1028	Short-chain dehydrogenase reductase Sdr
EI983_RS01900	COG2124	cytochrome p450
EI983_RS01905	COG4948	Mandelate Racemase Muconate Lactonizing
EI983_RS01910	COG5598	trimethylamine methyltransferase
EI983_RS01920	COG1012	belongs to the aldehyde dehydrogenase family
EI983_RS01925	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EI983_RS01930	COG2186	Transcriptional regulator
EI983_RS01935	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EI983_RS01940	COG1132	(ABC) transporter
EI983_RS01945	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EI983_RS01950	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EI983_RS01965	COG1473	amidohydrolase
EI983_RS01985	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EI983_RS01990	COG0564	pseudouridine synthase activity
EI983_RS02005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EI983_RS02010	COG4597	amino acid ABC transporter
EI983_RS02015	COG0765	amino acid transport
EI983_RS02020	COG1126	abc transporter atp-binding protein
EI983_RS02045	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EI983_RS02050	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EI983_RS02060	COG0706	membrane insertase activity
EI983_RS02065	COG5001	Diguanylate cyclase
EI983_RS02070	COG0037	tRNA processing
EI983_RS02080	COG0745	RESPONSE REGULATOR receiver
EI983_RS02090	COG0708	Exodeoxyribonuclease III
EI983_RS02105	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EI983_RS02110	COG2835	tetraacyldisaccharide 4'-kinase activity
EI983_RS02125	COG0793	Belongs to the peptidase S41A family
EI983_RS02135	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EI983_RS02140	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EI983_RS02145	COG0799	negative regulation of ribosome biogenesis
EI983_RS02160	COG3655	Transcriptional regulator
EI983_RS02165	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
EI983_RS02165	COG3264	Mechanosensitive ion channel
EI983_RS02170	COG0123	including yeast histone deacetylase and acetoin utilization protein
EI983_RS02175	COG0583	DNA-binding transcription factor activity
EI983_RS02185	COG0517	IMP dehydrogenase activity
EI983_RS02185	COG4175	Glycine betaine
EI983_RS02200	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EI983_RS02210	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EI983_RS02235	COG0288	reversible hydration of carbon dioxide
EI983_RS02245	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EI983_RS02250	COG0791	NLP P60 protein
EI983_RS02270	COG0625	glutathione transferase activity
EI983_RS02275	COG0501	Belongs to the peptidase M48B family
EI983_RS02295	COG0587	DNA-directed DNA polymerase activity
EI983_RS02300	COG1678	Uncharacterized ACR, COG1678
EI983_RS02320	COG0521	Mo-molybdopterin cofactor biosynthetic process
EI983_RS02330	COG1573	uracil-dna glycosylase
EI983_RS02335	COG0540	Belongs to the ATCase OTCase family
EI983_RS02350	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EI983_RS02355	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EI983_RS02380	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EI983_RS02385	COG0424	maF-like protein
EI983_RS02395	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
EI983_RS02435	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EI983_RS02445	COG1278	Cold shock
EI983_RS02455	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EI983_RS02540	COG0318	PFAM AMP-dependent synthetase and ligase
EI983_RS02560	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EI983_RS02580	COG0745	RESPONSE REGULATOR receiver
EI983_RS02605	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EI983_RS02615	COG0631	protein serine/threonine phosphatase activity
EI983_RS02645	COG4206	TonB-dependent receptor
EI983_RS02650	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EI983_RS02655	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EI983_RS02660	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EI983_RS02680	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EI983_RS02690	COG3047	cAMP biosynthetic process
EI983_RS02690	COG2885	chlorophyll binding
EI983_RS02700	COG0583	DNA-binding transcription factor activity
EI983_RS02710	COG1643	Atp-dependent helicase
EI983_RS02715	COG1703	isobutyryl-CoA mutase activity
EI983_RS02720	COG1132	(ABC) transporter
EI983_RS02730	COG0019	diaminopimelate decarboxylase activity
EI983_RS02740	COG0165	Argininosuccinate lyase
EI983_RS02745	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EI983_RS02760	COG3273	potassium ion transport
EI983_RS02760	COG0471	metal ion transport
EI983_RS02790	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EI983_RS02805	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EI983_RS02810	COG1994	Peptidase M50
EI983_RS02810	COG0517	IMP dehydrogenase activity
EI983_RS02815	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EI983_RS02820	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EI983_RS02830	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EI983_RS02845	COG2884	Cell division ATP-binding protein ftsE
EI983_RS02885	COG0508	dehydrogenase complex catalyzes the overall conversion of
EI983_RS02890	COG0567	Dehydrogenase, E1 component
EI983_RS02900	COG0045	succinate-CoA ligase (ADP-forming) activity
EI983_RS02905	COG0039	L-malate dehydrogenase activity
EI983_RS02935	COG2030	dehydratase
EI983_RS02945	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EI983_RS02950	COG1214	PFAM Peptidase M22, glycoprotease
EI983_RS02955	COG0454	-acetyltransferase
EI983_RS02955	COG0456	acetyltransferase
EI983_RS02960	COG1744	ABC transporter substrate-binding protein PnrA-like
EI983_RS02965	COG3845	ABC transporter
EI983_RS02970	COG4603	Belongs to the binding-protein-dependent transport system permease family
EI983_RS02980	COG1079	Belongs to the binding-protein-dependent transport system permease family
EI983_RS02985	COG0730	response to heat
EI983_RS03030	COG2808	Putative FMN-binding domain
EI983_RS03035	COG1028	Short-chain dehydrogenase reductase Sdr
EI983_RS03075	COG0604	alcohol dehydrogenase
EI983_RS03080	COG2937	Belongs to the GPAT DAPAT family
EI983_RS03085	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EI983_RS03085	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EI983_RS03100	COG0813	purine-nucleoside phosphorylase activity
EI983_RS03105	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
EI983_RS03115	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EI983_RS03120	COG0792	nuclease activity
EI983_RS03135	COG0606	chelatase, subunit chli
EI983_RS03150	COG0180	Tryptophanyl-tRNA synthetase
EI983_RS03155	COG2235	arginine
EI983_RS03160	COG2514	catechol 2,3-dioxygenase activity
EI983_RS03255	COG0756	dUTP diphosphatase activity
EI983_RS03260	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EI983_RS03265	COG0339	signal peptide processing
EI983_RS03270	COG2223	nitrite transmembrane transporter activity
EI983_RS03305	COG1573	uracil-dna glycosylase
EI983_RS03315	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EI983_RS03320	COG0772	Belongs to the SEDS family
EI983_RS03325	COG0768	penicillin binding
EI983_RS03355	COG1573	uracil-dna glycosylase
EI983_RS03365	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EI983_RS03380	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EI983_RS03385	COG5328	Belongs to the UPF0262 family
EI983_RS03410	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EI983_RS03415	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EI983_RS03420	COG0287	Prephenate dehydrogenase
EI983_RS03435	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
EI983_RS03460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EI983_RS03480	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EI983_RS03485	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EI983_RS03490	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EI983_RS03495	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EI983_RS03500	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EI983_RS03520	COG2267	carboxylic ester hydrolase activity
EI983_RS03530	COG2983	Belongs to the UPF0260 family
EI983_RS03535	COG0196	riboflavin kinase activity
EI983_RS03540	COG2030	dehydratase
EI983_RS03550	COG0583	DNA-binding transcription factor activity
EI983_RS03555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EI983_RS03565	COG1942	4-Oxalocrotonate Tautomerase
EI983_RS03575	COG0154	amidase activity
EI983_RS03585	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EI983_RS03590	COG0251	oxidation-reduction process
EI983_RS03600	COG1435	thymidine kinase activity
EI983_RS03610	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EI983_RS03630	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EI983_RS03635	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EI983_RS03660	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EI983_RS03670	COG1496	oxidoreductase activity
EI983_RS03680	COG1522	sequence-specific DNA binding
EI983_RS03685	COG0492	ferredoxin-NADP+ reductase activity
EI983_RS03695	COG2046	Belongs to the sulfate adenylyltransferase family
EI983_RS03695	COG0529	Catalyzes the synthesis of activated sulfate
EI983_RS03715	COG3135	benzoate transporter
EI983_RS03725	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EI983_RS03745	COG2135	peptidase activity
EI983_RS03750	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EI983_RS03755	COG0539	negative regulation of cytoplasmic translation
EI983_RS03760	COG0776	regulation of translation
EI983_RS03770	COG0135	phosphoribosylanthranilate isomerase activity
EI983_RS03790	COG0133	tryptophan synthase activity
EI983_RS03825	COG2423	ornithine cyclodeaminase activity
EI983_RS03830	COG3616	Alanine racemase, N-terminal domain
EI983_RS03835	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EI983_RS03840	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EI983_RS03845	COG1414	Transcriptional regulator
EI983_RS03865	COG0193	aminoacyl-tRNA hydrolase activity
EI983_RS03870	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EI983_RS03875	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EI983_RS03885	COG1012	belongs to the aldehyde dehydrogenase family
EI983_RS03885	COG2030	dehydratase
EI983_RS03890	COG0159	tryptophan synthase activity
EI983_RS03900	COG0012	GTP binding
EI983_RS03905	COG1522	sequence-specific DNA binding
EI983_RS03910	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EI983_RS03965	COG0745	RESPONSE REGULATOR receiver
EI983_RS04030	COG3710	Transcriptional regulator
EI983_RS04030	COG0457	Tetratricopeptide repeat
EI983_RS04075	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EI983_RS04085	COG0385	Bile acid
EI983_RS04100	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EI983_RS04110	COG0583	DNA-binding transcription factor activity
EI983_RS04115	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EI983_RS04120	COG1280	lysine exporter protein (LysE YggA)
EI983_RS04125	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EI983_RS04130	COG0659	secondary active sulfate transmembrane transporter activity
EI983_RS04140	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EI983_RS04155	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EI983_RS04180	COG0725	ABC transporter, periplasmic molybdate-binding protein
EI983_RS04185	COG4149	molybdate abc transporter
EI983_RS04190	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EI983_RS04195	COG1178	ABC-type Fe3 transport system permease component
EI983_RS04215	COG1012	belongs to the aldehyde dehydrogenase family
EI983_RS04220	COG0583	DNA-binding transcription factor activity
EI983_RS04225	COG0747	negative chemotaxis
EI983_RS04235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EI983_RS04240	COG0601	transmembrane transport
EI983_RS04245	COG1840	ABC-type Fe3 transport system, periplasmic component
EI983_RS04250	COG2759	Belongs to the formate--tetrahydrofolate ligase family
EI983_RS04255	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EI983_RS04275	COG1201	RNA secondary structure unwinding
EI983_RS04330	COG4964	Belongs to the GSP D family
EI983_RS04370	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EI983_RS04370	COG1754	DNA topoisomerase type I activity
EI983_RS04380	COG0758	DNA mediated transformation
EI983_RS04385	COG0312	modulator of DNA gyrase
EI983_RS04395	COG0109	protoheme IX farnesyltransferase activity
EI983_RS04400	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
EI983_RS04420	COG0612	Peptidase, M16
EI983_RS04450	COG0277	FAD linked oxidase domain protein
EI983_RS04470	COG1960	acyl-CoA dehydrogenase activity
EI983_RS04475	COG3246	L-lysine catabolic process to acetate
EI983_RS04485	COG1250	3-hydroxyacyl-CoA dehydrogenase
EI983_RS04495	COG1012	belongs to the aldehyde dehydrogenase family
EI983_RS04500	COG2267	carboxylic ester hydrolase activity
EI983_RS04515	COG1250	3-hydroxyacyl-CoA dehydrogenase
EI983_RS04520	COG1028	Short-chain dehydrogenase reductase Sdr
EI983_RS04525	COG1028	Short-chain dehydrogenase reductase Sdr
EI983_RS04530	COG3119	arylsulfatase activity
EI983_RS04535	COG4638	Rieske (2fe-2S)
EI983_RS04545	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EI983_RS04560	COG3842	ATPase activity
EI983_RS04570	COG1175	transmembrane transport
EI983_RS04575	COG0395	ABC-type sugar transport system, permease component
EI983_RS04595	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EI983_RS04615	COG1802	Transcriptional regulator
EI983_RS04635	COG0811	peptide transport
EI983_RS04650	COG0101	tRNA pseudouridine synthase activity
EI983_RS04655	COG3106	COG3106 Predicted ATPase
EI983_RS04665	COG3768	UPF0283 membrane protein
EI983_RS04670	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EI983_RS04685	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EI983_RS04690	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EI983_RS04715	COG0495	leucyl-tRNA aminoacylation
EI983_RS04745	COG2081	HI0933 family
EI983_RS04750	COG3264	Mechanosensitive ion channel
EI983_RS04750	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
EI983_RS04760	COG2132	Multicopper oxidase
EI983_RS04785	COG0312	modulator of DNA gyrase
EI983_RS04795	COG0697	spore germination
EI983_RS04805	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EI983_RS04810	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EI983_RS04815	COG0049	tRNA binding
EI983_RS04820	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EI983_RS04825	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EI983_RS04830	COG0051	transcription antitermination factor activity, RNA binding
EI983_RS04835	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EI983_RS04840	COG0088	Forms part of the polypeptide exit tunnel
EI983_RS04845	COG0089	rRNA binding
EI983_RS04855	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EI983_RS04860	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EI983_RS04865	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EI983_RS04870	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EI983_RS04875	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EI983_RS04890	COG0255	Belongs to the universal ribosomal protein uL29 family
EI983_RS04895	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EI983_RS04900	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EI983_RS04905	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EI983_RS04910	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EI983_RS04915	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EI983_RS04920	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EI983_RS04925	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EI983_RS04930	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EI983_RS04935	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EI983_RS04940	COG1841	ribosomal large subunit assembly
EI983_RS04955	COG1917	Cupin 2, conserved barrel domain protein
EI983_RS04960	COG0200	Binds to the 23S rRNA
EI983_RS04965	COG0201	protein transport
EI983_RS04970	COG0563	adenylate kinase activity
EI983_RS04975	COG2200	EAL domain
EI983_RS04980	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EI983_RS04985	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EI983_RS04990	COG0202	RNA polymerase activity
EI983_RS04995	COG0203	ribosomal protein L17
EI983_RS05005	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EI983_RS05010	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EI983_RS05015	COG0747	negative chemotaxis
EI983_RS05020	COG0747	negative chemotaxis
EI983_RS05025	COG0601	transmembrane transport
EI983_RS05030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EI983_RS05040	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EI983_RS05045	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EI983_RS05050	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EI983_RS05055	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EI983_RS05065	COG0745	RESPONSE REGULATOR receiver
EI983_RS05070	COG0346	lactoylglutathione lyase activity
EI983_RS05080	COG0525	valine-tRNA ligase activity
EI983_RS05140	COG0151	Belongs to the GarS family
EI983_RS05150	COG1570	exodeoxyribonuclease VII activity
EI983_RS05180	COG0552	protein localization to endoplasmic reticulum
EI983_RS05200	COG2917	probably involved in intracellular septation
EI983_RS05215	COG0006	proline dipeptidase activity
EI983_RS05225	COG0583	DNA-binding transcription factor activity
EI983_RS05230	COG1469	GTP cyclohydrolase I activity
EI983_RS05240	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EI983_RS05260	COG0752	glycyl-tRNA synthetase alpha subunit
EI983_RS05270	COG0751	glycine-tRNA ligase activity
EI983_RS05275	COG0574	Belongs to the PEP-utilizing enzyme family
EI983_RS05275	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EI983_RS05290	COG1610	YqeY-like protein
EI983_RS05295	COG0505	Belongs to the CarA family
EI983_RS05320	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EI983_RS05335	COG1522	sequence-specific DNA binding
EI983_RS05340	COG1522	sequence-specific DNA binding
EI983_RS05345	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EI983_RS05355	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EI983_RS05360	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EI983_RS05370	COG0583	DNA-binding transcription factor activity
EI983_RS05380	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EI983_RS05395	COG3474	cytochrome
EI983_RS05400	COG0321	lipoyl(octanoyl) transferase activity
EI983_RS05420	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
EI983_RS05425	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
EI983_RS05435	COG1233	COG1233 Phytoene dehydrogenase and related
EI983_RS05440	COG1562	ergosterol biosynthetic process
EI983_RS05445	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
EI983_RS05450	COG5621	secreted hydrolase
EI983_RS05455	COG1233	COG1233 Phytoene dehydrogenase and related
EI983_RS05460	COG0142	geranyltranstransferase activity
EI983_RS05465	COG0500	methyltransferase
EI983_RS05470	COG1063	alcohol dehydrogenase
EI983_RS05475	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
EI983_RS05480	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
EI983_RS05485	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
EI983_RS05520	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EI983_RS05525	COG0156	8-amino-7-oxononanoate synthase activity
EI983_RS05535	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EI983_RS05570	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
EI983_RS05575	COG1429	ligase activity, forming nitrogen-metal bonds
EI983_RS05580	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
EI983_RS05585	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
EI983_RS05605	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EI983_RS05610	COG2211	Major facilitator Superfamily
EI983_RS05615	COG0644	oxidoreductase
EI983_RS05625	COG0697	spore germination
EI983_RS05640	COG0747	negative chemotaxis
EI983_RS05645	COG1309	transcriptional regulator
EI983_RS05650	COG3119	arylsulfatase activity
EI983_RS05655	COG0625	glutathione transferase activity
EI983_RS05670	COG2267	carboxylic ester hydrolase activity
EI983_RS05675	COG3800	Transcriptional regulator
EI983_RS05675	COG1396	sequence-specific DNA binding
EI983_RS05680	COG2814	Major facilitator Superfamily
EI983_RS05685	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EI983_RS05710	COG4770	biotin carboxylase activity
EI983_RS05735	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EI983_RS05735	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EI983_RS05760	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EI983_RS05775	COG0248	Ppx GppA phosphatase
EI983_RS05780	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EI983_RS05790	COG0628	permease
EI983_RS05795	COG0442	prolyl-tRNA aminoacylation
EI983_RS05810	COG1136	(ABC) transporter
EI983_RS05815	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EI983_RS05885	COG2116	formate transmembrane transporter activity
EI983_RS05890	COG0556	nucleotide-excision repair
EI983_RS05900	COG2326	polyphosphate kinase activity
EI983_RS05905	COG0534	Mate efflux family protein
EI983_RS05920	COG1396	sequence-specific DNA binding
EI983_RS05930	COG1846	Transcriptional regulator
EI983_RS05950	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EI983_RS05965	COG1278	Cold shock
EI983_RS05970	COG1393	Belongs to the ArsC family
EI983_RS05985	COG3220	belongs to the UPF0276 family
EI983_RS05995	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EI983_RS06035	COG3243	poly(R)-hydroxyalkanoic acid synthase
EI983_RS06050	COG0583	DNA-binding transcription factor activity
EI983_RS06060	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EI983_RS06065	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EI983_RS06075	COG0174	glutamine synthetase
EI983_RS06080	COG0519	Catalyzes the synthesis of GMP from XMP
EI983_RS06080	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EI983_RS06085	COG0174	glutamine synthetase
EI983_RS06095	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EI983_RS06110	COG0504	CTP synthase activity
EI983_RS06145	COG4215	(ABC) transporter
EI983_RS06170	COG1227	inorganic diphosphatase activity
EI983_RS06185	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EI983_RS06190	COG0459	protein refolding
EI983_RS06195	COG1692	metallophosphoesterase
EI983_RS06205	COG0471	metal ion transport
EI983_RS06205	COG3273	potassium ion transport
EI983_RS06210	COG0471	metal ion transport
EI983_RS06210	COG3273	potassium ion transport
EI983_RS06215	COG0217	transcriptional regulatory protein
EI983_RS06225	COG1741	Belongs to the pirin family
EI983_RS06245	COG3454	Phosphonate metabolism
EI983_RS06250	COG1032	radical SAM domain protein
EI983_RS06255	COG1719	4-vinyl reductase, 4VR
EI983_RS06265	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EI983_RS06280	COG0071	Belongs to the small heat shock protein (HSP20) family
EI983_RS06290	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EI983_RS06315	COG1024	Enoyl-CoA hydratase
EI983_RS06315	COG1250	3-hydroxyacyl-CoA dehydrogenase
EI983_RS06330	COG0183	Belongs to the thiolase family
EI983_RS06335	COG0625	glutathione transferase activity
EI983_RS06340	COG1960	acyl-CoA dehydrogenase activity
EI983_RS06350	COG1960	acyl-CoA dehydrogenase activity
EI983_RS06375	COG0534	Mate efflux family protein
EI983_RS06385	COG1393	Belongs to the ArsC family
EI983_RS06400	COG0737	Belongs to the 5'-nucleotidase family
EI983_RS06425	COG1609	Transcriptional regulator
EI983_RS06440	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EI983_RS06445	COG0604	alcohol dehydrogenase
EI983_RS06455	COG2001	Belongs to the MraZ family
EI983_RS06460	COG0275	rRNA processing
EI983_RS06475	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EI983_RS06485	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EI983_RS06495	COG1028	Short-chain dehydrogenase reductase Sdr
EI983_RS06505	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EI983_RS06520	COG2081	HI0933 family
EI983_RS06530	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EI983_RS06535	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EI983_RS06545	COG0531	amino acid
EI983_RS06560	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EI983_RS06565	COG1181	Belongs to the D-alanine--D-alanine ligase family
EI983_RS06570	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EI983_RS06575	COG0849	cell division
EI983_RS06580	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EI983_RS06585	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
EI983_RS06590	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EI983_RS06605	COG0277	FAD linked oxidase domain protein
EI983_RS06620	COG0006	proline dipeptidase activity
EI983_RS06655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EI983_RS06660	COG0601	transmembrane transport
EI983_RS06670	COG4172	Belongs to the ABC transporter superfamily
EI983_RS06675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EI983_RS06680	COG1473	amidohydrolase
EI983_RS06690	COG1519	Transferase
EI983_RS06695	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EI983_RS06715	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EI983_RS06720	COG0546	phosphoglycolate phosphatase activity
EI983_RS06725	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EI983_RS06735	COG1960	acyl-CoA dehydrogenase activity
EI983_RS06750	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EI983_RS06755	COG3047	cAMP biosynthetic process
EI983_RS06760	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EI983_RS06770	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EI983_RS06820	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EI983_RS06825	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EI983_RS06830	COG0649	NAD binding
EI983_RS06890	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EI983_RS06895	COG2226	methyltransferase
EI983_RS06900	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EI983_RS06915	COG0713	ATP synthesis coupled electron transport
EI983_RS06930	COG1007	ATP synthesis coupled electron transport
EI983_RS06940	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EI983_RS06955	COG0513	Belongs to the DEAD box helicase family
EI983_RS06965	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EI983_RS06985	COG4335	DNA alkylation repair
EI983_RS06995	COG3842	ATPase activity
EI983_RS07005	COG2226	methyltransferase
EI983_RS07015	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EI983_RS07020	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EI983_RS07030	COG0805	protein transport
EI983_RS07040	COG1028	Short-chain dehydrogenase reductase Sdr
EI983_RS07055	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EI983_RS07065	COG4221	oxidoreductase activity
EI983_RS07070	COG1268	BioY protein
EI983_RS07090	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EI983_RS07125	COG1127	ABC transporter
EI983_RS07130	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EI983_RS07135	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EI983_RS07145	COG0305	Participates in initiation and elongation during chromosome replication
EI983_RS07150	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EI983_RS07155	COG5002	protein histidine kinase activity
EI983_RS07160	COG0418	dihydroorotase activity
EI983_RS07165	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EI983_RS07180	COG0542	response to heat
EI983_RS07200	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EI983_RS07230	COG2084	Dehydrogenase
EI983_RS07245	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EI983_RS07255	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EI983_RS07265	COG0006	proline dipeptidase activity
EI983_RS07275	COG0583	DNA-binding transcription factor activity
EI983_RS07290	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EI983_RS07295	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EI983_RS07300	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
EI983_RS07315	COG1138	Cytochrome C-type biogenesis protein
EI983_RS07320	COG3088	subunit of a heme lyase
EI983_RS07325	COG1024	Enoyl-CoA hydratase
EI983_RS07330	COG0372	Belongs to the citrate synthase family
EI983_RS07335	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EI983_RS07340	COG2333	competence protein COMEC
EI983_RS07340	COG0658	competence protein
EI983_RS07345	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EI983_RS07350	COG0303	'Molybdopterin
EI983_RS07360	COG0134	indole-3-glycerol-phosphate synthase activity
EI983_RS07365	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EI983_RS07395	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EI983_RS07405	COG0436	Aminotransferase
EI983_RS07410	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
EI983_RS07420	COG1280	lysine exporter protein (LysE YggA)
EI983_RS07425	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EI983_RS07430	COG0259	pyridoxamine-phosphate oxidase activity
EI983_RS07450	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EI983_RS07465	COG1215	transferase activity, transferring glycosyl groups
EI983_RS07470	COG4122	O-methyltransferase activity
EI983_RS07475	COG0006	proline dipeptidase activity
EI983_RS07490	COG2423	ornithine cyclodeaminase activity
EI983_RS07495	COG0010	Belongs to the arginase family
EI983_RS07505	COG4638	Rieske (2fe-2S)
EI983_RS07510	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EI983_RS07515	COG1238	metal cluster binding
EI983_RS07530	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EI983_RS07555	COG4536	flavin adenine dinucleotide binding
EI983_RS07565	COG4974	Belongs to the 'phage' integrase family
EI983_RS07575	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EI983_RS07580	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EI983_RS07585	COG0798	PFAM Bile acid sodium symporter
EI983_RS07595	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EI983_RS07600	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EI983_RS07605	COG3473	Maleate cis-trans isomerase
EI983_RS07615	COG2755	lipolytic protein G-D-S-L family
EI983_RS07615	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EI983_RS07630	COG0519	Catalyzes the synthesis of GMP from XMP
EI983_RS07630	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EI983_RS07635	COG5598	trimethylamine methyltransferase
EI983_RS07655	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EI983_RS07660	COG0583	DNA-binding transcription factor activity
EI983_RS07665	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EI983_RS07680	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EI983_RS07705	COG0433	COG0433 Predicted ATPase
EI983_RS07715	COG1722	exodeoxyribonuclease VII activity
EI983_RS07720	COG0142	geranyltranstransferase activity
EI983_RS07725	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EI983_RS07730	COG0482	sulfurtransferase activity
EI983_RS07745	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EI983_RS07750	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EI983_RS07765	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EI983_RS07770	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EI983_RS07780	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EI983_RS07785	COG1858	cytochrome C peroxidase
EI983_RS07790	COG1024	Enoyl-CoA hydratase
EI983_RS07815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EI983_RS07830	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EI983_RS07850	COG1309	transcriptional regulator
EI983_RS07855	COG2326	polyphosphate kinase activity
EI983_RS07860	COG0596	Alpha beta hydrolase
EI983_RS07865	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EI983_RS07890	COG0440	acetolactate synthase activity
EI983_RS07905	COG0028	Belongs to the TPP enzyme family
EI983_RS07920	COG5285	phytanoyl-CoA dioxygenase
EI983_RS07945	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EI983_RS07950	COG4638	Rieske (2fe-2S)
EI983_RS07955	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
EI983_RS07980	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EI983_RS08015	COG0535	radical SAM domain protein
EI983_RS08020	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EI983_RS08025	COG0363	glucosamine-6-phosphate deaminase activity
EI983_RS08030	COG0166	Belongs to the GPI family
EI983_RS08045	COG0148	phosphopyruvate hydratase activity
EI983_RS08050	COG0697	spore germination
EI983_RS08060	COG0513	Belongs to the DEAD box helicase family
EI983_RS08075	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EI983_RS08090	COG3956	TIGRFAM MazG family protein
EI983_RS08095	COG1473	amidohydrolase
EI983_RS08100	COG0010	Belongs to the arginase family
EI983_RS08115	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EI983_RS08120	COG2890	protein-(glutamine-N5) methyltransferase activity
EI983_RS08130	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EI983_RS08135	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EI983_RS08145	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EI983_RS08160	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EI983_RS08175	COG2095	MarC family integral membrane protein
EI983_RS08180	COG2226	methyltransferase
EI983_RS08190	COG0488	(ABC) transporter
EI983_RS08200	COG0105	UTP biosynthetic process
EI983_RS08215	COG4176	ABC-type proline glycine betaine transport system permease component
EI983_RS08220	COG4175	Glycine betaine
EI983_RS08220	COG3448	diguanylate cyclase activity
EI983_RS08235	COG1012	belongs to the aldehyde dehydrogenase family
EI983_RS08240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EI983_RS08250	COG2267	carboxylic ester hydrolase activity
EI983_RS08275	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EI983_RS08280	COG2218	PFAM glutamate synthase alpha subunit domain protein
EI983_RS08285	COG0069	glutamate synthase activity
EI983_RS08300	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EI983_RS08305	COG0045	succinate-CoA ligase (ADP-forming) activity
EI983_RS08330	COG2771	luxR family
EI983_RS08350	COG0154	amidase activity
EI983_RS08405	COG4221	oxidoreductase activity
EI983_RS08420	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EI983_RS08445	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EI983_RS08450	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EI983_RS08455	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EI983_RS08465	COG2166	iron-sulfur cluster assembly
EI983_RS08475	COG5012	cobalamin binding
EI983_RS08485	COG1410	methionine synthase
EI983_RS08485	COG0646	methionine synthase
EI983_RS08500	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EI983_RS08505	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EI983_RS08515	COG0047	phosphoribosylformylglycinamidine synthase activity
EI983_RS08525	COG2204	response regulator
EI983_RS08535	COG1530	ribonuclease E activity
EI983_RS08540	COG0425	Belongs to the sulfur carrier protein TusA family
EI983_RS08545	COG0785	Cytochrome C biogenesis protein
EI983_RS08575	COG0114	fumarate hydratase activity
EI983_RS08605	COG0697	spore germination
EI983_RS08610	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EI983_RS08615	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EI983_RS08620	COG0415	Belongs to the DNA photolyase family
EI983_RS08625	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EI983_RS08635	COG0494	nUDIX hydrolase
EI983_RS08645	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
EI983_RS08645	COG3264	Mechanosensitive ion channel
EI983_RS08650	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EI983_RS08675	COG3391	amine dehydrogenase activity
EI983_RS08685	COG1832	CoA-binding protein
EI983_RS08715	COG1216	Glycosyl transferase, family 2
EI983_RS08735	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EI983_RS08735	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EI983_RS08740	COG2010	Cytochrome c
EI983_RS08750	COG3794	PFAM blue (type 1) copper domain protein
EI983_RS08755	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EI983_RS08770	COG1845	cytochrome c oxidase, subunit III
EI983_RS08780	COG0714	Associated with various cellular activities
EI983_RS08790	COG2010	Cytochrome c
EI983_RS08795	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EI983_RS08795	COG1648	precorrin-2 dehydrogenase activity
EI983_RS08800	COG2010	Cytochrome c
EI983_RS08825	COG0535	radical SAM domain protein
EI983_RS08845	COG0156	8-amino-7-oxononanoate synthase activity
EI983_RS08875	COG4263	nitrous-oxide reductase activity
EI983_RS08910	COG5598	trimethylamine methyltransferase
EI983_RS08915	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EI983_RS08940	COG4566	intracellular signal transduction
EI983_RS08950	COG1410	methionine synthase
EI983_RS08950	COG0646	methionine synthase
EI983_RS08955	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EI983_RS08965	COG0248	Ppx GppA phosphatase
EI983_RS08970	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EI983_RS08985	COG1561	YicC-like family, N-terminal region
EI983_RS08990	COG0194	GDP metabolic process
EI983_RS09000	COG5002	protein histidine kinase activity
EI983_RS09005	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EI983_RS09010	COG0573	inorganic phosphate transmembrane transporter activity
EI983_RS09020	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EI983_RS09030	COG0745	RESPONSE REGULATOR receiver
EI983_RS09035	COG0583	DNA-binding transcription factor activity
EI983_RS09040	COG1960	acyl-CoA dehydrogenase activity
EI983_RS09045	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EI983_RS09060	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EI983_RS09065	COG0052	Belongs to the universal ribosomal protein uS2 family
EI983_RS09080	COG1028	Short-chain dehydrogenase reductase Sdr
EI983_RS09090	COG2313	pseudouridylate synthase activity
EI983_RS09105	COG1028	Short-chain dehydrogenase reductase Sdr
EI983_RS09110	COG4166	transmembrane transport
EI983_RS09125	COG3119	arylsulfatase activity
EI983_RS09130	COG1396	sequence-specific DNA binding
EI983_RS09145	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EI983_RS09150	COG2814	Major facilitator Superfamily
EI983_RS09155	COG2838	Isocitrate dehydrogenase
EI983_RS09165	COG2076	Multidrug Resistance protein
EI983_RS09175	COG1522	sequence-specific DNA binding
EI983_RS09180	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EI983_RS09185	COG1923	regulation of RNA biosynthetic process
EI983_RS09190	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EI983_RS09195	COG0569	domain protein
EI983_RS09205	COG2204	response regulator
EI983_RS09210	COG5000	phosphorelay sensor kinase activity
EI983_RS09215	COG2204	response regulator
EI983_RS09220	COG3852	Histidine kinase
EI983_RS09225	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EI983_RS09230	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EI983_RS09230	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EI983_RS09240	COG1058	Belongs to the CinA family
EI983_RS09240	COG1546	Belongs to the CinA family
EI983_RS09245	COG0004	ammonium transporteR
EI983_RS09255	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EI983_RS09270	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EI983_RS09285	COG0719	Fe-S assembly protein
EI983_RS09290	COG0396	ATPase activity
EI983_RS09300	COG0393	Putative heavy-metal-binding
EI983_RS09315	COG0719	Fe-S assembly protein
EI983_RS09325	COG1959	2 iron, 2 sulfur cluster binding
EI983_RS09330	COG2945	thiolester hydrolase activity
EI983_RS09340	COG2353	YceI-like domain
EI983_RS09355	COG0360	Binds together with S18 to 16S ribosomal RNA
EI983_RS09360	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EI983_RS09365	COG0359	binds to the 23S rRNA
EI983_RS09370	COG2197	response regulator
EI983_RS09375	COG3916	Acyl-homoserine-lactone synthase
EI983_RS09380	COG0544	peptidyl-prolyl cis-trans isomerase activity
EI983_RS09395	COG3750	Belongs to the UPF0335 family
EI983_RS09405	COG1024	Enoyl-CoA hydratase
EI983_RS09405	COG1250	3-hydroxyacyl-CoA dehydrogenase
EI983_RS09420	COG5002	protein histidine kinase activity
EI983_RS09430	COG0745	RESPONSE REGULATOR receiver
EI983_RS09460	COG0410	ABC transporter
EI983_RS09465	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EI983_RS09475	COG0697	spore germination
EI983_RS09485	COG0511	ligase activity, forming carbon-carbon bonds
EI983_RS09490	COG0439	Biotin carboxylase
EI983_RS09495	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EI983_RS09515	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EI983_RS09520	COG0740	serine-type endopeptidase activity
EI983_RS09525	COG1960	acyl-CoA dehydrogenase activity
EI983_RS09535	COG2205	protein histidine kinase activity
EI983_RS09535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EI983_RS09545	COG4251	negative regulation of phosphorylation
EI983_RS09550	COG2201	protein-glutamate methylesterase activity
EI983_RS09570	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EI983_RS09600	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EI983_RS09635	COG0408	coproporphyrinogen oxidase activity
EI983_RS09650	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EI983_RS09660	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EI983_RS09685	COG5425	PFAM Usg family protein
EI983_RS09690	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EI983_RS09710	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EI983_RS09720	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EI983_RS09725	COG1612	heme a metabolic process
EI983_RS09735	COG0352	thiamine-phosphate diphosphorylase activity
EI983_RS09760	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EI983_RS09765	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EI983_RS09770	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EI983_RS09790	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EI983_RS09795	COG3743	rRNA binding
EI983_RS09795	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EI983_RS09855	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EI983_RS09860	COG3002	Belongs to the UPF0753 family
EI983_RS09865	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EI983_RS09870	COG1177	transmembrane transport
EI983_RS09880	COG3842	ATPase activity
EI983_RS09895	COG0583	DNA-binding transcription factor activity
EI983_RS09905	COG2072	flavoprotein involved in K transport
EI983_RS09910	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
EI983_RS09925	COG2133	pyrroloquinoline quinone binding
EI983_RS09960	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EI983_RS09965	COG3494	Protein of unknown function (DUF1009)
EI983_RS09970	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EI983_RS09975	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EI983_RS09985	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EI983_RS09990	COG0750	zinc metalloprotease
EI983_RS09995	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EI983_RS10000	COG4589	Belongs to the CDS family
EI983_RS10005	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EI983_RS10010	COG0233	cytoplasmic translational termination
EI983_RS10015	COG0528	UMP kinase activity
EI983_RS10020	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EI983_RS10035	COG0741	lytic transglycosylase activity
EI983_RS10035	COG0739	heme binding
EI983_RS10035	COG1196	nuclear chromosome segregation
EI983_RS10040	COG0629	single-stranded DNA binding
EI983_RS10050	COG1217	gtp-binding protein TYPA
EI983_RS10070	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EI983_RS10075	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EI983_RS10095	COG0516	GMP reductase activity
EI983_RS10095	COG0517	IMP dehydrogenase activity
EI983_RS10100	COG0010	Belongs to the arginase family
EI983_RS10105	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EI983_RS10110	COG0594	ribonuclease P activity
EI983_RS10115	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EI983_RS10125	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EI983_RS10160	COG3209	COG3209 Rhs family protein
EI983_RS10165	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EI983_RS10170	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EI983_RS10175	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EI983_RS10185	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EI983_RS10205	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EI983_RS10215	COG0488	(ABC) transporter
EI983_RS10235	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EI983_RS10240	COG0416	fatty acid biosynthetic process
EI983_RS10245	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EI983_RS10250	COG0776	regulation of translation
EI983_RS10265	COG0717	Belongs to the dCTP deaminase family
EI983_RS10275	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EI983_RS10280	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EI983_RS10295	COG0018	arginyl-trna synthetase
EI983_RS10300	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EI983_RS10305	COG0316	Belongs to the HesB IscA family
EI983_RS10315	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EI983_RS10325	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EI983_RS10355	COG0659	secondary active sulfate transmembrane transporter activity
EI983_RS10360	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EI983_RS10370	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EI983_RS10380	COG0436	Aminotransferase
EI983_RS10395	COG1063	alcohol dehydrogenase
EI983_RS10400	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EI983_RS10410	COG0156	8-amino-7-oxononanoate synthase activity
EI983_RS10450	COG0406	alpha-ribazole phosphatase activity
EI983_RS10460	COG0776	regulation of translation
EI983_RS10475	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EI983_RS10485	COG0343	queuine tRNA-ribosyltransferase activity
EI983_RS10500	COG4067	protein conserved in archaea
EI983_RS10500	COG0189	ligase activity
EI983_RS10505	COG0488	(ABC) transporter
EI983_RS10515	COG2151	metal-sulfur cluster biosynthetic enzyme
EI983_RS10535	COG0149	triose-phosphate isomerase activity
EI983_RS10540	COG1522	sequence-specific DNA binding
EI983_RS10545	COG1648	precorrin-2 dehydrogenase activity
EI983_RS10545	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EI983_RS10555	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EI983_RS10560	COG0175	sulfate reduction
EI983_RS10580	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EI983_RS10615	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EI983_RS10630	COG2354	Protein conserved in bacteria
EI983_RS10660	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EI983_RS10665	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EI983_RS10665	COG0617	tRNA 3'-terminal CCA addition
EI983_RS10665	COG0517	IMP dehydrogenase activity
EI983_RS10685	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
EI983_RS10690	COG1960	acyl-CoA dehydrogenase activity
EI983_RS10740	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EI983_RS10755	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EI983_RS10765	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EI983_RS10770	COG2833	Protein of unknown function (DUF455)
EI983_RS10775	COG0739	heme binding
EI983_RS10790	COG0583	DNA-binding transcription factor activity
EI983_RS10795	COG2226	methyltransferase
EI983_RS10825	COG2814	Major facilitator Superfamily
EI983_RS10835	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EI983_RS10840	COG0215	cysteine-tRNA ligase activity
EI983_RS10855	COG0789	Transcriptional regulator
EI983_RS10895	COG0126	phosphoglycerate kinase activity
EI983_RS10900	COG0306	phosphate transporter
EI983_RS10915	COG3588	fructose-bisphosphate aldolase
EI983_RS10920	COG1960	acyl-CoA dehydrogenase activity
EI983_RS10945	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EI983_RS10950	COG0508	dehydrogenase complex catalyzes the overall conversion of
EI983_RS10950	COG0022	dehydrogenase e1 component
EI983_RS10955	COG0508	dehydrogenase complex catalyzes the overall conversion of
EI983_RS10985	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EI983_RS10990	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EI983_RS11000	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EI983_RS11005	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EI983_RS11010	COG4133	protoheme IX ABC transporter activity
EI983_RS11015	COG3737	Protein of unknown function (DUF498/DUF598)
EI983_RS11025	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EI983_RS11030	COG1862	Preprotein translocase
EI983_RS11035	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EI983_RS11045	COG3239	Fatty acid desaturase
EI983_RS11055	COG1160	GTP binding
EI983_RS11075	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EI983_RS11085	COG5265	(ABC) transporter
EI983_RS11095	COG3842	ATPase activity
EI983_RS11100	COG0395	ABC-type sugar transport system, permease component
EI983_RS11105	COG1176	ABC-type spermidine putrescine transport system, permease component I
EI983_RS11115	COG0583	DNA-binding transcription factor activity
EI983_RS11125	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EI983_RS11140	COG1611	Belongs to the LOG family
EI983_RS11145	COG2962	Rard protein
EI983_RS11170	COG0446	pyridine nucleotide-disulphide oxidoreductase
EI983_RS11170	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EI983_RS11185	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EI983_RS11190	COG4235	cytochrome complex assembly
EI983_RS11195	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EI983_RS11210	COG0730	response to heat
EI983_RS11215	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EI983_RS11225	COG1012	belongs to the aldehyde dehydrogenase family
EI983_RS11255	COG3246	L-lysine catabolic process to acetate
EI983_RS11265	COG1397	ADP-ribosylglycohydrolase
EI983_RS11275	COG1012	belongs to the aldehyde dehydrogenase family
EI983_RS11295	COG4638	Rieske (2fe-2S)
EI983_RS11310	COG1063	alcohol dehydrogenase
EI983_RS11315	COG1917	Cupin 2, conserved barrel domain protein
EI983_RS11325	COG4948	Mandelate Racemase Muconate Lactonizing
EI983_RS11340	COG4948	Mandelate Racemase Muconate Lactonizing
EI983_RS11345	COG4948	Mandelate Racemase Muconate Lactonizing
EI983_RS11350	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EI983_RS11355	COG0004	ammonium transporteR
EI983_RS11365	COG0004	ammonium transporteR
EI983_RS11380	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EI983_RS11385	COG2239	Acts as a magnesium transporter
EI983_RS11390	COG0402	S-adenosylhomocysteine deaminase activity
EI983_RS11405	COG0483	inositol monophosphate 1-phosphatase activity
EI983_RS11420	COG0583	DNA-binding transcription factor activity
EI983_RS11430	COG0670	Belongs to the BI1 family
EI983_RS11440	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EI983_RS11465	COG0154	amidase activity
EI983_RS11470	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EI983_RS11475	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EI983_RS11480	COG0590	tRNA wobble adenosine to inosine editing
EI983_RS11485	COG1187	pseudouridine synthase activity
EI983_RS11495	COG0583	DNA-binding transcription factor activity
EI983_RS11505	COG0861	Integral membrane protein TerC family
EI983_RS11520	COG3853	Toxic anion resistance protein (TelA)
EI983_RS11550	COG0071	Belongs to the small heat shock protein (HSP20) family
EI983_RS11555	COG1490	D-aminoacyl-tRNA deacylase activity
EI983_RS11560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EI983_RS11565	COG2274	protein secretion by the type I secretion system
EI983_RS11585	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EI983_RS11590	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EI983_RS11595	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EI983_RS11600	COG1253	flavin adenine dinucleotide binding
EI983_RS11605	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EI983_RS11610	COG1702	phosphate starvation-inducible protein PhoH
EI983_RS11620	COG2885	chlorophyll binding
EI983_RS11630	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EI983_RS11655	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EI983_RS11660	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EI983_RS11670	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EI983_RS11675	COG0735	belongs to the Fur family
EI983_RS11680	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EI983_RS11685	COG0604	alcohol dehydrogenase
EI983_RS11695	COG1047	Peptidyl-prolyl cis-trans
EI983_RS11705	COG2267	carboxylic ester hydrolase activity
EI983_RS11730	COG0596	Alpha beta hydrolase
EI983_RS11750	COG0154	amidase activity
EI983_RS11755	COG4948	Mandelate Racemase Muconate Lactonizing
EI983_RS11765	COG1234	tRNA 3'-trailer cleavage
EI983_RS11770	COG0084	hydrolase, TatD family'
EI983_RS11780	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EI983_RS11785	COG1686	Belongs to the peptidase S11 family
EI983_RS11800	COG0583	DNA-binding transcription factor activity
EI983_RS11805	COG4638	Rieske (2fe-2S)
EI983_RS11810	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EI983_RS11820	COG1028	Short-chain dehydrogenase reductase Sdr
EI983_RS11840	COG4176	ABC-type proline glycine betaine transport system permease component
EI983_RS11850	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EI983_RS11860	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
EI983_RS11935	COG0667	Aldo Keto reductase
EI983_RS11940	COG2353	YceI-like domain
EI983_RS11945	COG0477	Major facilitator Superfamily
EI983_RS11950	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EI983_RS11955	COG0840	transmembrane signaling receptor activity
EI983_RS11990	COG0483	inositol monophosphate 1-phosphatase activity
EI983_RS11995	COG0583	DNA-binding transcription factor activity
EI983_RS12000	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EI983_RS12005	COG0489	protein tyrosine kinase activity
EI983_RS12015	COG0110	maltose O-acetyltransferase activity
EI983_RS12045	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EI983_RS12060	COG0346	lactoylglutathione lyase activity
EI983_RS12080	COG0131	Imidazoleglycerol-phosphate dehydratase
EI983_RS12085	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EI983_RS12100	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EI983_RS12115	COG0107	imidazoleglycerol-phosphate synthase activity
EI983_RS12120	COG0140	phosphoribosyl-ATP diphosphatase activity
EI983_RS12130	COG1832	CoA-binding protein
EI983_RS12140	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EI983_RS12165	COG2873	o-acetylhomoserine
EI983_RS12180	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EI983_RS12185	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
EI983_RS12190	COG1329	Transcriptional regulator
EI983_RS12195	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EI983_RS12225	COG0179	Fumarylacetoacetate (FAA) hydrolase
EI983_RS12235	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EI983_RS12235	COG1793	dna ligase
EI983_RS12255	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EI983_RS12275	COG0564	pseudouridine synthase activity
EI983_RS12325	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EI983_RS12330	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EI983_RS12335	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EI983_RS12335	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EI983_RS12340	COG0583	DNA-binding transcription factor activity
EI983_RS12345	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EI983_RS12355	COG0655	NAD(P)H dehydrogenase (quinone) activity
EI983_RS12360	COG0010	Belongs to the arginase family
EI983_RS12370	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EI983_RS12385	COG1028	Short-chain dehydrogenase reductase Sdr
EI983_RS12435	COG0308	aminopeptidase N
EI983_RS12450	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EI983_RS12490	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EI983_RS12490	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EI983_RS12505	COG0432	Pfam Uncharacterised protein family UPF0047
EI983_RS12525	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EI983_RS12545	COG0446	pyridine nucleotide-disulphide oxidoreductase
EI983_RS12545	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EI983_RS12550	COG4311	Sarcosine oxidase, delta subunit
EI983_RS12560	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EI983_RS12565	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EI983_RS12595	COG1741	Belongs to the pirin family
EI983_RS12600	COG1309	transcriptional regulator
EI983_RS12620	COG1494	fructose-1,6-bisphosphatase
EI983_RS12625	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EI983_RS12625	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EI983_RS12660	COG1132	(ABC) transporter
EI983_RS12685	COG2909	trisaccharide binding
EI983_RS12710	COG0559	Belongs to the binding-protein-dependent transport system permease family
EI983_RS12720	COG1960	acyl-CoA dehydrogenase activity
EI983_RS12725	COG1064	alcohol dehydrogenase
EI983_RS12750	COG2308	Evidence 4 Homologs of previously reported genes of
EI983_RS12770	COG3246	L-lysine catabolic process to acetate
EI983_RS12775	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EI983_RS12780	COG3842	ATPase activity
EI983_RS12790	COG1177	transmembrane transport
EI983_RS12795	COG1176	ABC-type spermidine putrescine transport system, permease component I
EI983_RS12800	COG0583	DNA-binding transcription factor activity
EI983_RS12820	COG0318	PFAM AMP-dependent synthetase and ligase
EI983_RS12835	COG0745	RESPONSE REGULATOR receiver
EI983_RS12865	COG1309	transcriptional regulator
EI983_RS12875	COG0747	negative chemotaxis
EI983_RS12885	COG3842	ATPase activity
EI983_RS12900	COG1177	transmembrane transport
EI983_RS12905	COG1028	Short-chain dehydrogenase reductase Sdr
EI983_RS12910	COG2423	ornithine cyclodeaminase activity
EI983_RS12915	COG1902	pentaerythritol trinitrate reductase activity
EI983_RS12915	COG0446	pyridine nucleotide-disulphide oxidoreductase
EI983_RS12920	COG2226	methyltransferase
EI983_RS12930	COG1733	regulation of RNA biosynthetic process
EI983_RS12950	COG0446	pyridine nucleotide-disulphide oxidoreductase
EI983_RS12950	COG1902	pentaerythritol trinitrate reductase activity
EI983_RS12965	COG2267	carboxylic ester hydrolase activity
EI983_RS12975	COG0583	DNA-binding transcription factor activity
EI983_RS13000	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EI983_RS13005	COG2423	ornithine cyclodeaminase activity
EI983_RS13025	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EI983_RS13050	COG3842	ATPase activity
EI983_RS13055	COG0395	ABC-type sugar transport system, permease component
EI983_RS13060	COG1175	transmembrane transport
EI983_RS13070	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EI983_RS13075	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EI983_RS13085	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EI983_RS13090	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EI983_RS13105	COG4336	lyase activity
EI983_RS13110	COG0583	DNA-binding transcription factor activity
EI983_RS13115	COG3842	ATPase activity
EI983_RS13120	COG1176	ABC-type spermidine putrescine transport system, permease component I
EI983_RS13125	COG1177	transmembrane transport
EI983_RS13135	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EI983_RS13145	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EI983_RS13155	COG0295	cytidine deaminase activity
EI983_RS13160	COG0281	malic enzyme
EI983_RS13160	COG0280	phosphate acetyltransferase
EI983_RS13185	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EI983_RS13195	COG0596	Alpha beta hydrolase
EI983_RS13230	COG1943	Transposase
EI983_RS13235	COG0481	GTPase activity
EI983_RS13255	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EI983_RS13260	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EI983_RS13260	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EI983_RS13270	COG0583	DNA-binding transcription factor activity
EI983_RS13280	COG0842	Transport permease protein
EI983_RS13290	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EI983_RS13295	COG1272	protein, Hemolysin III
EI983_RS13325	COG0778	Nitroreductase
EI983_RS13335	COG1024	Enoyl-CoA hydratase
EI983_RS13345	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EI983_RS13355	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EI983_RS13370	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EI983_RS13380	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EI983_RS13400	COG1492	cobalamin metabolic process
EI983_RS13415	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EI983_RS13465	COG0330	HflC and HflK could
EI983_RS13495	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EI983_RS13505	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EI983_RS13510	COG0459	protein refolding
EI983_RS13525	COG0398	Pfam SNARE associated Golgi protein
EI983_RS13540	COG3550	peptidyl-serine autophosphorylation
EI983_RS13560	COG1349	DNA-binding transcription factor activity
EI983_RS13565	COG3842	ATPase activity
EI983_RS13575	COG1175	transmembrane transport
EI983_RS13580	COG0395	ABC-type sugar transport system, permease component
EI983_RS13585	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EI983_RS13600	COG2027	D-alanyl-D-alanine carboxypeptidase
EI983_RS13605	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EI983_RS13610	COG5001	Diguanylate cyclase
EI983_RS13610	COG3300	MHYT domain
EI983_RS13615	COG0488	(ABC) transporter
EI983_RS13625	COG1376	ErfK ybiS ycfS ynhG family protein
EI983_RS13630	COG1278	Cold shock
EI983_RS13640	COG4181	ATPase activity
EI983_RS13670	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EI983_RS13670	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EI983_RS13675	COG0509	glycine decarboxylation via glycine cleavage system
EI983_RS13680	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EI983_RS13685	COG1959	2 iron, 2 sulfur cluster binding
EI983_RS13700	COG0534	Mate efflux family protein
EI983_RS13710	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EI983_RS13745	COG3046	protein related to deoxyribodipyrimidine photolyase
EI983_RS13755	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EI983_RS13765	COG1309	transcriptional regulator
EI983_RS13775	COG0318	PFAM AMP-dependent synthetase and ligase
EI983_RS13795	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EI983_RS13810	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EI983_RS13815	COG0037	tRNA processing
EI983_RS13825	COG2885	chlorophyll binding
EI983_RS13830	COG0823	Involved in the tonB-independent uptake of proteins
EI983_RS13840	COG0848	biopolymer transport protein
EI983_RS13850	COG0824	Thioesterase
EI983_RS13875	COG2255	four-way junction helicase activity
EI983_RS13880	COG0632	four-way junction helicase activity
EI983_RS13885	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EI983_RS13915	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EI983_RS13920	COG1335	isochorismatase
EI983_RS13930	COG1028	Short-chain dehydrogenase reductase Sdr
EI983_RS13935	COG1177	transmembrane transport
EI983_RS13945	COG3842	ATPase activity
EI983_RS13955	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
EI983_RS13975	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
EI983_RS13985	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EI983_RS13990	COG1349	DNA-binding transcription factor activity
EI983_RS14015	COG1183	phosphatidylcholine synthase activity
EI983_RS14025	COG2885	chlorophyll binding
EI983_RS14040	COG1058	Belongs to the CinA family
EI983_RS14040	COG1546	Belongs to the CinA family
EI983_RS14045	COG1489	DNA binding
EI983_RS14050	COG1960	acyl-CoA dehydrogenase activity
EI983_RS14055	COG0024	Methionine aminopeptidase
EI983_RS14060	COG2096	Adenosyltransferase
EI983_RS14070	COG0300	oxidoreductase activity
EI983_RS14080	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EI983_RS14090	COG2124	cytochrome p450
EI983_RS14115	COG0747	negative chemotaxis
EI983_RS14125	COG0697	spore germination
EI983_RS14215	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EI983_RS14220	COG0250	Participates in transcription elongation, termination and antitermination
EI983_RS14230	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EI983_RS14235	COG0081	regulation of translation
EI983_RS14240	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EI983_RS14245	COG0222	ribosome binding
EI983_RS14250	COG0085	RNA polymerase activity
EI983_RS14255	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EI983_RS14275	COG1250	3-hydroxyacyl-CoA dehydrogenase
EI983_RS14285	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EI983_RS14295	COG1660	Displays ATPase and GTPase activities
EI983_RS14305	COG2205	protein histidine kinase activity
EI983_RS14310	COG0745	RESPONSE REGULATOR receiver
EI983_RS14315	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EI983_RS14320	COG0729	surface antigen
EI983_RS14330	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EI983_RS14340	COG0402	S-adenosylhomocysteine deaminase activity
EI983_RS14345	COG1079	Belongs to the binding-protein-dependent transport system permease family
EI983_RS14350	COG4603	Belongs to the binding-protein-dependent transport system permease family
EI983_RS14355	COG3845	ABC transporter
EI983_RS14390	COG0174	glutamine synthetase
EI983_RS14410	COG3246	L-lysine catabolic process to acetate
EI983_RS14435	COG1250	3-hydroxyacyl-CoA dehydrogenase
EI983_RS14435	COG0824	Thioesterase
EI983_RS14440	COG1960	acyl-CoA dehydrogenase activity
EI983_RS14495	COG0346	lactoylglutathione lyase activity
EI983_RS14510	COG1381	Involved in DNA repair and RecF pathway recombination
EI983_RS14525	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EI983_RS14530	COG0571	ribonuclease III activity
EI983_RS14535	COG0681	Belongs to the peptidase S26 family
EI983_RS14540	COG0681	Belongs to the peptidase S26 family
EI983_RS14545	COG0736	holo-[acyl-carrier-protein] synthase activity
EI983_RS14560	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EI983_RS14575	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EI983_RS14580	COG1758	RNA polymerase activity
EI983_RS14585	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EI983_RS14595	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EI983_RS14605	COG1280	lysine exporter protein (LysE YggA)
EI983_RS14610	COG4106	trans-aconitate 2-methyltransferase activity
EI983_RS14615	COG0328	RNA-DNA hybrid ribonuclease activity
EI983_RS14620	COG2860	membrane
EI983_RS14635	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EI983_RS14640	COG0242	peptide deformylase activity
EI983_RS14645	COG0242	peptide deformylase activity
EI983_RS14650	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EI983_RS14660	COG0435	Glutathione S-transferase
EI983_RS14665	COG0006	proline dipeptidase activity
EI983_RS14685	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
EI983_RS14695	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EI983_RS14695	COG0116	Belongs to the methyltransferase superfamily
EI983_RS14715	COG0454	-acetyltransferase
EI983_RS14715	COG0456	acetyltransferase
EI983_RS14730	COG4948	Mandelate Racemase Muconate Lactonizing
EI983_RS14765	COG0493	'glutamate synthase
EI983_RS14775	COG2226	methyltransferase
EI983_RS14795	COG1309	transcriptional regulator
EI983_RS14800	COG1309	transcriptional regulator
EI983_RS14825	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EI983_RS14830	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EI983_RS14835	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EI983_RS14840	COG1309	transcriptional regulator
EI983_RS14850	COG1686	Belongs to the peptidase S11 family
EI983_RS14870	COG0348	domain, Protein
EI983_RS14875	COG0583	DNA-binding transcription factor activity
EI983_RS14880	COG3706	GGDEF domain
EI983_RS14885	COG2010	Cytochrome c
EI983_RS14910	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EI983_RS14915	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EI983_RS14925	COG4172	Belongs to the ABC transporter superfamily
EI983_RS14930	COG4239	(ABC) transporter, permease
EI983_RS14935	COG4174	ABC transporter (Permease)
EI983_RS14950	COG1605	Chorismate mutase
EI983_RS14950	COG0077	Prephenate dehydratase
EI983_RS14960	COG0747	negative chemotaxis
EI983_RS14980	COG4585	Histidine kinase
EI983_RS14990	COG1796	DNA polymerase
EI983_RS14990	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EI983_RS15005	COG2816	NAD+ diphosphatase activity
EI983_RS15010	COG0737	Belongs to the 5'-nucleotidase family
EI983_RS15025	COG2321	neutral zinc metallopeptidase
EI983_RS15035	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EI983_RS15040	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EI983_RS15120	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
EI983_RS15125	COG0463	Glycosyl transferase, family 2
EI983_RS15145	COG3321	synthase
EI983_RS15145	COG1028	Short-chain dehydrogenase reductase Sdr
EI983_RS15145	COG0604	alcohol dehydrogenase
EI983_RS15155	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EI983_RS15165	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EI983_RS15195	COG0564	pseudouridine synthase activity
EI983_RS15235	COG0604	alcohol dehydrogenase
EI983_RS15245	COG1280	lysine exporter protein (LysE YggA)
EI983_RS15255	COG3791	Glutathione-dependent formaldehyde-activating
EI983_RS15275	COG1956	GAF domain-containing protein
EI983_RS15280	COG0183	Belongs to the thiolase family
EI983_RS15285	COG1366	Belongs to the anti-sigma-factor antagonist family
EI983_RS15295	COG0405	Gamma-glutamyltransferase
EI983_RS15310	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EI983_RS15315	COG1674	ftsk spoiiie
EI983_RS15330	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EI983_RS15340	COG0742	ribosomal rna small subunit methyltransferase
EI983_RS15350	COG0678	peroxiredoxin activity
EI983_RS15355	COG2154	pterin-4-alpha-carbinolamine dehydratase
EI983_RS15365	COG0584	glycerophosphoryl diester phosphodiesterase
EI983_RS15375	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EI983_RS15385	COG2853	Lipoprotein
EI983_RS15400	COG0347	Belongs to the P(II) protein family
EI983_RS15405	COG0004	ammonium transporteR
EI983_RS15420	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
EI983_RS15425	COG1268	BioY protein
EI983_RS15435	COG1172	Belongs to the binding-protein-dependent transport system permease family
EI983_RS15440	COG1129	ABC transporter
EI983_RS15445	COG1879	ABC-type sugar transport system periplasmic component
EI983_RS15450	COG1984	allophanate hydrolase subunit 2
EI983_RS15460	COG0439	Biotin carboxylase
EI983_RS15465	COG0511	ligase activity, forming carbon-carbon bonds
EI983_RS15475	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EI983_RS15480	COG0583	DNA-binding transcription factor activity
EI983_RS15495	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EI983_RS15510	COG1126	abc transporter atp-binding protein
EI983_RS15515	COG3457	Alanine racemase
EI983_RS15525	COG0010	Belongs to the arginase family
EI983_RS15565	COG0129	dihydroxy-acid dehydratase activity
EI983_RS15570	COG1266	CAAX protease self-immunity
EI983_RS15575	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EI983_RS15580	COG0285	dihydrofolate synthase activity
EI983_RS15595	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EI983_RS15610	COG0356	it plays a direct role in the translocation of protons across the membrane
EI983_RS15640	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
EI983_RS15655	COG2226	methyltransferase
EI983_RS15670	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EI983_RS15685	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EI983_RS15730	COG0228	four-way junction DNA binding
EI983_RS15735	COG0778	Nitroreductase
EI983_RS15745	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EI983_RS15755	COG0336	Belongs to the RNA methyltransferase TrmD family
EI983_RS15765	COG0335	large ribosomal subunit rRNA binding
EI983_RS15770	COG0254	rRNA binding
EI983_RS15790	COG2151	metal-sulfur cluster biosynthetic enzyme
EI983_RS15790	COG0489	protein tyrosine kinase activity
EI983_RS15825	COG0837	glucose binding
EI983_RS15835	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EI983_RS15845	COG1012	belongs to the aldehyde dehydrogenase family
EI983_RS15855	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EI983_RS15870	COG0747	negative chemotaxis
EI983_RS15880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EI983_RS15885	COG0444	Belongs to the ABC transporter superfamily
EI983_RS15905	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EI983_RS15910	COG0741	lytic transglycosylase activity
EI983_RS15940	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
EI983_RS15950	COG2078	PFAM AMMECR1 domain protein
EI983_RS15965	COG0583	DNA-binding transcription factor activity
EI983_RS15970	COG0446	pyridine nucleotide-disulphide oxidoreductase
EI983_RS15970	COG1902	pentaerythritol trinitrate reductase activity
EI983_RS15990	COG0825	malonyl-CoA metabolic process
EI983_RS15995	COG1802	Transcriptional regulator
EI983_RS16020	COG0577	efflux transmembrane transporter activity
EI983_RS16025	COG1136	(ABC) transporter
EI983_RS16030	COG2111	Na H antiporter
EI983_RS16030	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EI983_RS16035	COG1006	Multisubunit Na H antiporter MnhC subunit
EI983_RS16040	COG0651	ATP synthesis coupled electron transport
EI983_RS16045	COG1863	multisubunit Na H antiporter MnhE subunit
EI983_RS16050	COG2212	antiporter activity
EI983_RS16055	COG1320	monovalent cation:proton antiporter activity
EI983_RS16060	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
EI983_RS16065	COG0840	transmembrane signaling receptor activity
EI983_RS16085	COG0745	RESPONSE REGULATOR receiver
EI983_RS16090	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EI983_RS16105	COG0745	RESPONSE REGULATOR receiver
EI983_RS16155	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EI983_RS16180	COG4143	(ABC) transporter
EI983_RS16185	COG1178	ABC-type Fe3 transport system permease component
EI983_RS16190	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
EI983_RS16195	COG0656	L-ascorbic acid biosynthetic process
EI983_RS16205	COG2140	Oxalate decarboxylase
EI983_RS16220	COG4948	Mandelate Racemase Muconate Lactonizing
EI983_RS16225	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EI983_RS16230	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EI983_RS16235	COG0124	histidyl-tRNA synthetase
EI983_RS16240	COG2900	Belongs to the SlyX family
EI983_RS16260	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EI983_RS16270	COG3845	ABC transporter
EI983_RS16275	COG4603	Belongs to the binding-protein-dependent transport system permease family
EI983_RS16280	COG1079	Belongs to the binding-protein-dependent transport system permease family
EI983_RS16295	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EI983_RS16310	COG0405	Gamma-glutamyltransferase
EI983_RS16330	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EI983_RS16350	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EI983_RS16355	COG3257	ureidoglycine aminohydrolase activity
EI983_RS16360	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
EI983_RS16390	COG0559	Belongs to the binding-protein-dependent transport system permease family
EI983_RS16415	COG2226	methyltransferase
EI983_RS16430	COG0277	FAD linked oxidase domain protein
EI983_RS16430	COG0247	lactate metabolic process
EI983_RS16435	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EI983_RS16440	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EI983_RS16455	COG0747	negative chemotaxis
EI983_RS16460	COG0601	transmembrane transport
EI983_RS16470	COG0444	Belongs to the ABC transporter superfamily
EI983_RS16475	COG4608	Belongs to the ABC transporter superfamily
EI983_RS16495	COG1404	Belongs to the peptidase S8 family
EI983_RS16520	COG3448	diguanylate cyclase activity
EI983_RS16520	COG4175	Glycine betaine
EI983_RS16530	COG1349	DNA-binding transcription factor activity
EI983_RS16535	COG1760	l-serine dehydratase
EI983_RS16540	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EI983_RS16550	COG0330	HflC and HflK could
EI983_RS16555	COG0330	HflC and HflK could
EI983_RS16575	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EI983_RS16585	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EI983_RS16590	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EI983_RS16615	COG0138	bifunctional purine biosynthesis protein purh
EI983_RS16630	COG0612	Peptidase, M16
EI983_RS16635	COG0612	Peptidase, M16
EI983_RS16645	COG1012	belongs to the aldehyde dehydrogenase family
EI983_RS16650	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EI983_RS16655	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EI983_RS16660	COG0314	molybdopterin synthase activity
EI983_RS16670	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EI983_RS16680	COG0322	excinuclease ABC activity
EI983_RS16685	COG1028	Short-chain dehydrogenase reductase Sdr
EI983_RS16700	COG0616	signal peptide processing
EI983_RS16700	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EI983_RS16705	COG0842	Transport permease protein
EI983_RS16710	COG1131	(ABC) transporter
EI983_RS16730	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EI983_RS16735	COG2378	regulation of single-species biofilm formation
EI983_RS16760	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EI983_RS16770	COG2897	thiosulfate sulfurtransferase activity
EI983_RS16825	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
EI983_RS16835	COG1671	Belongs to the UPF0178 family
EI983_RS16850	COG2423	ornithine cyclodeaminase activity
EI983_RS16855	COG2267	carboxylic ester hydrolase activity
EI983_RS16870	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EI983_RS16875	COG2267	carboxylic ester hydrolase activity
EI983_RS16885	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EI983_RS16980	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EI983_RS16985	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EI983_RS17000	COG1194	a g-specific adenine glycosylase
EI983_RS17010	COG1609	Transcriptional regulator
EI983_RS17020	COG3173	Aminoglycoside phosphotransferase
EI983_RS17035	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EI983_RS17040	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EI983_RS17055	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EI983_RS17085	COG2391	methyltransferase activity
EI983_RS17095	COG0446	pyridine nucleotide-disulphide oxidoreductase
EI983_RS17115	COG0737	Belongs to the 5'-nucleotidase family
EI983_RS17120	COG3258	Cytochrome c
EI983_RS17145	COG0785	Cytochrome C biogenesis protein
EI983_RS17155	COG0640	Transcriptional regulator
EI983_RS17160	COG2391	methyltransferase activity
EI983_RS17165	COG5002	protein histidine kinase activity
EI983_RS17165	COG2176	DNA-directed DNA polymerase activity
EI983_RS17180	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EI983_RS17190	COG0563	adenylate kinase activity
EI983_RS17195	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EI983_RS17215	COG1519	Transferase
EI983_RS17220	COG0519	Catalyzes the synthesis of GMP from XMP
EI983_RS17230	COG1051	belongs to the nudix hydrolase family
EI983_RS17235	COG0243	molybdopterin cofactor binding
EI983_RS17240	COG0437	4 iron, 4 sulfur cluster binding
EI983_RS17285	COG3191	aminopeptidase activity
EI983_RS17295	COG1012	belongs to the aldehyde dehydrogenase family
EI983_RS17305	COG1595	DNA-templated transcription, initiation
EI983_RS17310	COG2304	oxidoreductase activity
EI983_RS17315	COG0071	Belongs to the small heat shock protein (HSP20) family
EI983_RS17325	COG3591	Belongs to the peptidase S1B family
EI983_RS17330	COG0247	lactate metabolic process
EI983_RS17340	COG0277	FAD linked oxidase domain protein
EI983_RS17345	COG0277	FAD linked oxidase domain protein
EI983_RS17375	COG0714	Associated with various cellular activities
EI983_RS17385	COG3622	Belongs to the hyi family
EI983_RS17415	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EI983_RS17415	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EI983_RS17425	COG1131	(ABC) transporter
EI983_RS17445	COG2070	2-Nitropropane dioxygenase
EI983_RS17460	COG0318	PFAM AMP-dependent synthetase and ligase
EI983_RS17495	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EI983_RS17510	COG2818	Glycosylase
EI983_RS17515	COG2200	EAL domain
EI983_RS17530	COG1028	Short-chain dehydrogenase reductase Sdr
EI983_RS17535	COG0583	DNA-binding transcription factor activity
EI983_RS17545	COG2813	Specifically methylates the guanine in position
EI983_RS17555	COG0142	geranyltranstransferase activity
EI983_RS17560	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EI983_RS17575	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EI983_RS17585	COG2951	lytic endotransglycosylase activity
EI983_RS17600	COG0557	exoribonuclease II activity
EI983_RS17610	COG2153	protein acetylation
EI983_RS17615	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EI983_RS17640	COG2171	N-acyltransferase activity
EI983_RS17680	COG3830	Belongs to the UPF0237 family
EI983_RS17680	COG0560	Phosphoserine phosphatase
EI983_RS17685	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EI983_RS17690	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EI983_RS17725	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EI983_RS17795	COG4638	Rieske (2fe-2S)
EI983_RS17810	COG0668	transmembrane transport
EI983_RS17830	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EI983_RS17835	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
EI983_RS17855	COG0514	ATP-dependent DNA helicase (RecQ)
EI983_RS17860	COG3022	response to hydroperoxide
EI983_RS17870	COG2373	Large extracellular alpha-helical protein
EI983_RS17880	COG4953	penicillin-binding protein 1C
EI983_RS17885	COG0183	Belongs to the thiolase family
EI983_RS17890	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EI983_RS17910	COG0174	glutamine synthetase
EI983_RS17920	COG0473	3-isopropylmalate dehydrogenase activity
EI983_RS17925	COG0583	DNA-binding transcription factor activity
EI983_RS17950	COG0066	3-isopropylmalate dehydratase activity
EI983_RS17955	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EI983_RS17970	COG0745	RESPONSE REGULATOR receiver
EI983_RS17975	COG1846	Transcriptional regulator
EI983_RS17980	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EI983_RS18000	COG1176	ABC-type spermidine putrescine transport system, permease component I
EI983_RS18010	COG3842	ATPase activity
EI983_RS18015	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EI983_RS18020	COG1522	sequence-specific DNA binding
EI983_RS18025	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EI983_RS18030	COG0006	proline dipeptidase activity
EI983_RS18040	COG1802	Transcriptional regulator
EI983_RS18050	COG3842	ATPase activity
EI983_RS18055	COG1176	ABC-type spermidine putrescine transport system, permease component I
EI983_RS18060	COG1177	transmembrane transport
EI983_RS18065	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EI983_RS18080	COG2175	clavaminate synthase activity
EI983_RS18090	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EI983_RS18120	COG0446	pyridine nucleotide-disulphide oxidoreductase
EI983_RS18120	COG1902	pentaerythritol trinitrate reductase activity
EI983_RS18125	COG1063	alcohol dehydrogenase
EI983_RS18140	COG5598	trimethylamine methyltransferase
EI983_RS18160	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EI983_RS18170	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EI983_RS18185	COG1968	undecaprenyl-diphosphatase activity
EI983_RS18210	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EI983_RS18220	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EI983_RS18225	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EI983_RS18240	COG1137	ATPase activity
EI983_RS18245	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EI983_RS18250	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EI983_RS18275	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EI983_RS18280	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EI983_RS18285	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EI983_RS18315	COG0443	Heat shock 70 kDa protein
EI983_RS18320	COG0484	heat shock protein binding
EI983_RS18325	COG2003	Belongs to the UPF0758 family
EI983_RS18345	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EI983_RS18350	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EI983_RS18355	COG0494	nUDIX hydrolase
EI983_RS18360	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EI983_RS18375	COG0779	Required for maturation of 30S ribosomal subunits
EI983_RS18380	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EI983_RS18385	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EI983_RS18390	COG1121	(ABC) transporter
EI983_RS18405	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EI983_RS18415	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EI983_RS18425	COG1040	competence protein
EI983_RS18430	COG2226	methyltransferase
EI983_RS18460	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EI983_RS18465	COG0617	tRNA 3'-terminal CCA addition
EI983_RS18470	COG0494	nUDIX hydrolase
EI983_RS18485	COG0745	RESPONSE REGULATOR receiver
EI983_RS18495	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EI983_RS18500	COG0137	argininosuccinate synthase activity
EI983_RS18520	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EI983_RS18530	COG0280	phosphate acetyltransferase
EI983_RS18530	COG0281	malic enzyme
EI983_RS18535	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EI983_RS18545	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
EI983_RS18550	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EI983_RS18555	COG1420	regulation of RNA biosynthetic process
EI983_RS18560	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EI983_RS18565	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EI983_RS18570	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EI983_RS18575	COG2832	Protein of unknown function (DUF454)
EI983_RS18590	COG0357	Ribosomal RNA small subunit methyltransferase G
EI983_RS18595	COG0445	tRNA wobble uridine modification
EI983_RS18600	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EI983_RS18605	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EI983_RS18610	COG1981	membrane
EI983_RS18615	COG0424	maF-like protein
EI983_RS18625	COG0237	dephospho-CoA kinase activity
EI983_RS18630	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EI983_RS18635	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EI983_RS18665	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EI983_RS18675	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EI983_RS18685	COG1074	ATP-dependent DNA helicase activity
EI983_RS18695	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EI983_RS18700	COG3178	'Phosphotransferase
EI983_RS18705	COG0802	atpase or kinase
EI983_RS18720	COG1999	signal sequence binding
EI983_RS18725	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
EI983_RS18735	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
EI983_RS18740	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EI983_RS18770	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EI983_RS18775	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EI983_RS18850	COG0842	Transport permease protein
EI983_RS18855	COG0842	Transport permease protein
EI983_RS18855	COG1129	ABC transporter
EI983_RS18860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EI983_RS18905	COG4964	Belongs to the GSP D family
EI983_RS18970	COG1609	Transcriptional regulator
EI983_RS18985	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EI983_RS18990	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EI983_RS18990	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EI983_RS18995	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EI983_RS19000	COG1028	Short-chain dehydrogenase reductase Sdr
EI983_RS19020	COG0589	response to stress
EI983_RS19035	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EI983_RS19035	COG2010	Cytochrome c
EI983_RS19050	COG2197	response regulator
EI983_RS19070	COG2205	protein histidine kinase activity
EI983_RS19070	COG2198	Histidine kinase
EI983_RS19070	COG0784	Response regulator, receiver
EI983_RS19075	COG0277	FAD linked oxidase domain protein
EI983_RS19080	COG0247	lactate metabolic process
EI983_RS19085	COG1139	Iron-sulfur cluster binding protein
EI983_RS19135	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EI983_RS19150	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EI983_RS19160	COG2226	methyltransferase
EI983_RS19165	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EI983_RS19175	COG0268	Binds directly to 16S ribosomal RNA