locus-tag	class	description
FIU86_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FIU86_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FIU86_RS00025	COG0612	Peptidase, M16
FIU86_RS00030	COG0612	Peptidase, M16
FIU86_RS00045	COG0138	bifunctional purine biosynthesis protein purh
FIU86_RS00055	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FIU86_RS00055	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FIU86_RS00070	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FIU86_RS00075	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FIU86_RS00085	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FIU86_RS00095	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FIU86_RS00105	COG0330	HflC and HflK could
FIU86_RS00120	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FIU86_RS00125	COG1760	l-serine dehydratase
FIU86_RS00145	COG3708	Transcriptional regulator
FIU86_RS00145	COG2207	Transcriptional regulator
FIU86_RS00155	COG0446	pyridine nucleotide-disulphide oxidoreductase
FIU86_RS00155	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FIU86_RS00160	COG4311	Sarcosine oxidase, delta subunit
FIU86_RS00165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIU86_RS00170	COG4977	sequence-specific DNA binding
FIU86_RS00185	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FIU86_RS00200	COG0596	Alpha beta hydrolase
FIU86_RS00205	COG2423	ornithine cyclodeaminase activity
FIU86_RS00215	COG1671	Belongs to the UPF0178 family
FIU86_RS00225	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FIU86_RS00250	COG2897	thiosulfate sulfurtransferase activity
FIU86_RS00260	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FIU86_RS00265	COG0351	phosphomethylpyrimidine kinase
FIU86_RS00275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FIU86_RS00280	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FIU86_RS00285	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FIU86_RS00305	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FIU86_RS00310	COG0028	Belongs to the TPP enzyme family
FIU86_RS00320	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FIU86_RS00325	COG0243	molybdopterin cofactor binding
FIU86_RS00330	COG0437	4 iron, 4 sulfur cluster binding
FIU86_RS00365	COG3191	aminopeptidase activity
FIU86_RS00375	COG1012	belongs to the aldehyde dehydrogenase family
FIU86_RS00380	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FIU86_RS00390	COG2304	oxidoreductase activity
FIU86_RS00405	COG3591	Belongs to the peptidase S1B family
FIU86_RS00410	COG0247	lactate metabolic process
FIU86_RS00420	COG0277	FAD linked oxidase domain protein
FIU86_RS00425	COG0277	FAD linked oxidase domain protein
FIU86_RS00450	COG0714	Associated with various cellular activities
FIU86_RS00465	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FIU86_RS00465	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FIU86_RS00480	COG1131	(ABC) transporter
FIU86_RS00505	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIU86_RS00510	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FIU86_RS00515	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FIU86_RS00525	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FIU86_RS00535	COG1116	anion transmembrane transporter activity
FIU86_RS00540	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FIU86_RS00575	COG0825	malonyl-CoA metabolic process
FIU86_RS00590	COG1802	Transcriptional regulator
FIU86_RS00620	COG0784	Response regulator, receiver
FIU86_RS00640	COG1652	LysM domain
FIU86_RS00640	COG2823	Periplasmic or secreted lipoprotein
FIU86_RS00665	COG0022	dehydrogenase e1 component
FIU86_RS00670	COG1414	Transcriptional regulator
FIU86_RS00675	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FIU86_RS00680	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FIU86_RS00685	COG3616	Alanine racemase, N-terminal domain
FIU86_RS00690	COG2423	ornithine cyclodeaminase activity
FIU86_RS00720	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FIU86_RS00730	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FIU86_RS00745	COG1215	transferase activity, transferring glycosyl groups
FIU86_RS00780	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FIU86_RS00785	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FIU86_RS00790	COG2808	Putative FMN-binding domain
FIU86_RS00835	COG3239	Fatty acid desaturase
FIU86_RS00840	COG1194	a g-specific adenine glycosylase
FIU86_RS00850	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FIU86_RS00860	COG1663	tetraacyldisaccharide 4'-kinase activity
FIU86_RS00865	COG1519	Transferase
FIU86_RS00870	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FIU86_RS00895	COG3806	Anti-sigma factor
FIU86_RS00900	COG1595	DNA-templated transcription, initiation
FIU86_RS00925	COG4221	oxidoreductase activity
FIU86_RS00975	COG0784	Response regulator, receiver
FIU86_RS00975	COG4191	Histidine kinase
FIU86_RS00985	COG1022	Amp-dependent synthetase and ligase
FIU86_RS01005	COG0559	Belongs to the binding-protein-dependent transport system permease family
FIU86_RS01045	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FIU86_RS01050	COG3022	response to hydroperoxide
FIU86_RS01055	COG0514	ATP-dependent DNA helicase (RecQ)
FIU86_RS01075	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FIU86_RS01105	COG1131	(ABC) transporter
FIU86_RS01110	COG0842	Transport permease protein
FIU86_RS01115	COG0616	signal peptide processing
FIU86_RS01115	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FIU86_RS01130	COG0322	excinuclease ABC activity
FIU86_RS01135	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FIU86_RS01145	COG0314	molybdopterin synthase activity
FIU86_RS01160	COG1185	polyribonucleotide nucleotidyltransferase activity
FIU86_RS01170	COG1522	sequence-specific DNA binding
FIU86_RS01175	COG0686	Belongs to the AlaDH PNT family
FIU86_RS01200	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIU86_RS01210	COG1970	mechanosensitive ion channel activity
FIU86_RS01220	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
FIU86_RS01230	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FIU86_RS01235	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FIU86_RS01240	COG0006	proline dipeptidase activity
FIU86_RS01245	COG1473	amidohydrolase
FIU86_RS01255	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FIU86_RS01265	COG0546	phosphoglycolate phosphatase activity
FIU86_RS01275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FIU86_RS01280	COG4597	amino acid ABC transporter
FIU86_RS01285	COG0765	amino acid transport
FIU86_RS01290	COG1126	abc transporter atp-binding protein
FIU86_RS01315	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FIU86_RS01320	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FIU86_RS01330	COG0706	membrane insertase activity
FIU86_RS01335	COG4251	negative regulation of phosphorylation
FIU86_RS01335	COG2203	Gaf domain
FIU86_RS01335	COG3706	GGDEF domain
FIU86_RS01335	COG5001	Diguanylate cyclase
FIU86_RS01340	COG0037	tRNA processing
FIU86_RS01355	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FIU86_RS01360	COG0165	Argininosuccinate lyase
FIU86_RS01390	COG2884	Cell division ATP-binding protein ftsE
FIU86_RS01440	COG0508	dehydrogenase complex catalyzes the overall conversion of
FIU86_RS01465	COG0045	succinate-CoA ligase (ADP-forming) activity
FIU86_RS01475	COG0039	L-malate dehydrogenase activity
FIU86_RS01485	COG2301	Belongs to the HpcH HpaI aldolase family
FIU86_RS01500	COG2030	dehydratase
FIU86_RS01555	COG4452	Inner membrane protein CreD
FIU86_RS01585	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FIU86_RS01610	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FIU86_RS01620	COG0284	orotidine-5'-phosphate decarboxylase activity
FIU86_RS01665	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FIU86_RS01670	COG0069	glutamate synthase activity
FIU86_RS01675	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FIU86_RS01750	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
FIU86_RS01770	COG0187	DNA topoisomerase II activity
FIU86_RS01775	COG0837	glucose binding
FIU86_RS01795	COG1227	inorganic diphosphatase activity
FIU86_RS01810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FIU86_RS01815	COG0813	purine-nucleoside phosphorylase activity
FIU86_RS01840	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FIU86_RS01840	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FIU86_RS01850	COG0604	alcohol dehydrogenase
FIU86_RS01890	COG0793	Belongs to the peptidase S41A family
FIU86_RS01900	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FIU86_RS01905	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FIU86_RS01910	COG0799	negative regulation of ribosome biogenesis
FIU86_RS01915	COG2871	sodium ion transport
FIU86_RS01920	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FIU86_RS01920	COG3264	Mechanosensitive ion channel
FIU86_RS01925	COG0123	including yeast histone deacetylase and acetoin utilization protein
FIU86_RS01935	COG0583	DNA-binding transcription factor activity
FIU86_RS01945	COG4175	Glycine betaine
FIU86_RS01945	COG0517	IMP dehydrogenase activity
FIU86_RS01955	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FIU86_RS01995	COG0625	glutathione transferase activity
FIU86_RS02005	COG0655	NAD(P)H dehydrogenase (quinone) activity
FIU86_RS02010	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FIU86_RS02015	COG0741	lytic transglycosylase activity
FIU86_RS02020	COG2847	Copper chaperone PCu(A)C
FIU86_RS02030	COG0697	spore germination
FIU86_RS02035	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FIU86_RS02035	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIU86_RS02045	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
FIU86_RS02055	COG2078	PFAM AMMECR1 domain protein
FIU86_RS02065	COG0583	DNA-binding transcription factor activity
FIU86_RS02080	COG0446	pyridine nucleotide-disulphide oxidoreductase
FIU86_RS02080	COG1902	pentaerythritol trinitrate reductase activity
FIU86_RS02095	COG2514	catechol 2,3-dioxygenase activity
FIU86_RS02100	COG0180	Tryptophanyl-tRNA synthetase
FIU86_RS02125	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FIU86_RS02135	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FIU86_RS02140	COG0792	nuclease activity
FIU86_RS02145	COG0189	ligase activity
FIU86_RS02155	COG0606	chelatase, subunit chli
FIU86_RS02185	COG0756	dUTP diphosphatase activity
FIU86_RS02190	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FIU86_RS02195	COG0339	signal peptide processing
FIU86_RS02200	COG1051	belongs to the nudix hydrolase family
FIU86_RS02210	COG0587	DNA-directed DNA polymerase activity
FIU86_RS02245	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FIU86_RS02265	COG0288	reversible hydration of carbon dioxide
FIU86_RS02275	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FIU86_RS02280	COG0791	NLP P60 protein
FIU86_RS02290	COG2226	methyltransferase
FIU86_RS02295	COG2951	lytic endotransglycosylase activity
FIU86_RS02310	COG0557	exoribonuclease II activity
FIU86_RS02320	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FIU86_RS02340	COG2171	N-acyltransferase activity
FIU86_RS02350	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FIU86_RS02360	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FIU86_RS02365	COG1280	lysine exporter protein (LysE YggA)
FIU86_RS02370	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FIU86_RS02380	COG0668	transmembrane transport
FIU86_RS02390	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FIU86_RS02395	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FIU86_RS02430	COG1335	isochorismatase
FIU86_RS02435	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FIU86_RS02475	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FIU86_RS02480	COG2813	Specifically methylates the guanine in position
FIU86_RS02485	COG1028	Short-chain dehydrogenase reductase Sdr
FIU86_RS02490	COG0408	coproporphyrinogen oxidase activity
FIU86_RS02535	COG2321	neutral zinc metallopeptidase
FIU86_RS02550	COG0737	Belongs to the 5'-nucleotidase family
FIU86_RS02555	COG2816	NAD+ diphosphatase activity
FIU86_RS02585	COG4174	ABC transporter (Permease)
FIU86_RS02590	COG4239	(ABC) transporter, permease
FIU86_RS02595	COG4172	Belongs to the ABC transporter superfamily
FIU86_RS02600	COG1744	ABC transporter substrate-binding protein PnrA-like
FIU86_RS02610	COG3845	ABC transporter
FIU86_RS02615	COG4603	Belongs to the binding-protein-dependent transport system permease family
FIU86_RS02620	COG1280	lysine exporter protein (LysE YggA)
FIU86_RS02625	COG1079	Belongs to the binding-protein-dependent transport system permease family
FIU86_RS02630	COG0730	response to heat
FIU86_RS02655	COG0004	ammonium transporteR
FIU86_RS02660	COG0277	FAD linked oxidase domain protein
FIU86_RS02670	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FIU86_RS02680	COG1648	precorrin-2 dehydrogenase activity
FIU86_RS02680	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FIU86_RS02685	COG1797	cobyrinic acid a,c-diamide synthase activity
FIU86_RS02690	COG2875	Belongs to the precorrin methyltransferase family
FIU86_RS02705	COG2099	Precorrin-6x reductase
FIU86_RS02750	COG1492	cobalamin metabolic process
FIU86_RS02760	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FIU86_RS02780	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FIU86_RS02785	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FIU86_RS02790	COG0778	Nitroreductase
FIU86_RS02870	COG1132	(ABC) transporter
FIU86_RS02880	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FIU86_RS02895	COG1381	Involved in DNA repair and RecF pathway recombination
FIU86_RS02900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FIU86_RS02905	COG2133	pyrroloquinoline quinone binding
FIU86_RS02930	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
FIU86_RS02935	COG3639	organic phosphonate transmembrane transporter activity
FIU86_RS02940	COG3639	organic phosphonate transmembrane transporter activity
FIU86_RS02950	COG3454	Phosphonate metabolism
FIU86_RS02955	COG2188	Transcriptional regulator
FIU86_RS02960	COG3624	Phosphonate C-P lyase system protein PhnG
FIU86_RS02965	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
FIU86_RS02970	COG3626	phosphonate metabolism
FIU86_RS02975	COG0346	lactoylglutathione lyase activity
FIU86_RS02985	COG3627	carbon phosphorus lyase activity
FIU86_RS02990	COG4107	phosphonate C-P lyase system protein PhnK
FIU86_RS02995	COG4778	phosphonate C-P lyase system protein PhnL
FIU86_RS03005	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FIU86_RS03010	COG3454	Phosphonate metabolism
FIU86_RS03015	COG0179	Fumarylacetoacetate (FAA) hydrolase
FIU86_RS03035	COG0072	phenylalanine-tRNA ligase activity
FIU86_RS03035	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FIU86_RS03060	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FIU86_RS03065	COG0745	RESPONSE REGULATOR receiver
FIU86_RS03070	COG2205	protein histidine kinase activity
FIU86_RS03080	COG1660	Displays ATPase and GTPase activities
FIU86_RS03105	COG1250	3-hydroxyacyl-CoA dehydrogenase
FIU86_RS03135	COG0300	oxidoreductase activity
FIU86_RS03145	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FIU86_RS03165	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FIU86_RS03175	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
FIU86_RS03180	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FIU86_RS03190	COG0745	RESPONSE REGULATOR receiver
FIU86_RS03205	COG0250	Participates in transcription elongation, termination and antitermination
FIU86_RS03215	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FIU86_RS03220	COG0081	regulation of translation
FIU86_RS03225	COG2249	NAD(P)H dehydrogenase (quinone) activity
FIU86_RS03230	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FIU86_RS03235	COG0222	ribosome binding
FIU86_RS03240	COG0085	RNA polymerase activity
FIU86_RS03245	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FIU86_RS03250	COG0154	amidase activity
FIU86_RS03265	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FIU86_RS03280	COG0495	leucyl-tRNA aminoacylation
FIU86_RS03300	COG0625	glutathione transferase activity
FIU86_RS03305	COG2081	HI0933 family
FIU86_RS03310	COG3264	Mechanosensitive ion channel
FIU86_RS03310	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FIU86_RS03325	COG2132	Multicopper oxidase
FIU86_RS03330	COG1024	Enoyl-CoA hydratase
FIU86_RS03335	COG4221	oxidoreductase activity
FIU86_RS03355	COG0312	modulator of DNA gyrase
FIU86_RS03360	COG0483	inositol monophosphate 1-phosphatase activity
FIU86_RS03370	COG0697	spore germination
FIU86_RS03380	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FIU86_RS03385	COG0049	tRNA binding
FIU86_RS03390	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FIU86_RS03400	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FIU86_RS03405	COG0051	transcription antitermination factor activity, RNA binding
FIU86_RS03410	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FIU86_RS03415	COG0088	Forms part of the polypeptide exit tunnel
FIU86_RS03420	COG0089	rRNA binding
FIU86_RS03425	COG1278	Cold shock
FIU86_RS03430	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FIU86_RS03435	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FIU86_RS03440	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FIU86_RS03445	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FIU86_RS03450	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FIU86_RS03475	COG0255	Belongs to the universal ribosomal protein uL29 family
FIU86_RS03480	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FIU86_RS03485	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FIU86_RS03490	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FIU86_RS03495	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FIU86_RS03500	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FIU86_RS03505	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FIU86_RS03510	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FIU86_RS03515	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FIU86_RS03520	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FIU86_RS03525	COG1841	ribosomal large subunit assembly
FIU86_RS03540	COG1917	Cupin 2, conserved barrel domain protein
FIU86_RS03560	COG0745	RESPONSE REGULATOR receiver
FIU86_RS03565	COG0200	Binds to the 23S rRNA
FIU86_RS03570	COG0201	protein transport
FIU86_RS03575	COG0563	adenylate kinase activity
FIU86_RS03580	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FIU86_RS03585	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FIU86_RS03590	COG0202	RNA polymerase activity
FIU86_RS03595	COG0203	ribosomal protein L17
FIU86_RS03600	COG5622	Protein required for attachment to host cells
FIU86_RS03610	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FIU86_RS03615	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FIU86_RS03620	COG4166	transmembrane transport
FIU86_RS03630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIU86_RS03645	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FIU86_RS03645	COG0512	Glutamine amidotransferase of anthranilate synthase
FIU86_RS03655	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FIU86_RS03660	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FIU86_RS03685	COG0745	RESPONSE REGULATOR receiver
FIU86_RS03690	COG0346	lactoylglutathione lyase activity
FIU86_RS03700	COG1522	sequence-specific DNA binding
FIU86_RS03720	COG2814	Major facilitator Superfamily
FIU86_RS03725	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FIU86_RS03750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIU86_RS03755	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIU86_RS03765	COG0778	Nitroreductase
FIU86_RS03790	COG1272	protein, Hemolysin III
FIU86_RS03800	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FIU86_RS03810	COG0277	FAD linked oxidase domain protein
FIU86_RS03825	COG0489	protein tyrosine kinase activity
FIU86_RS03865	COG3383	formate dehydrogenase (NAD+) activity
FIU86_RS03865	COG0243	molybdopterin cofactor binding
FIU86_RS03870	COG0437	4 iron, 4 sulfur cluster binding
FIU86_RS03875	COG2864	formate dehydrogenase
FIU86_RS03885	COG2204	response regulator
FIU86_RS03890	COG3852	Histidine kinase
FIU86_RS03905	COG3853	Toxic anion resistance protein (TelA)
FIU86_RS03935	COG0071	Belongs to the small heat shock protein (HSP20) family
FIU86_RS03940	COG0318	PFAM AMP-dependent synthetase and ligase
FIU86_RS03945	COG1840	ABC-type Fe3 transport system, periplasmic component
FIU86_RS03960	COG3046	protein related to deoxyribodipyrimidine photolyase
FIU86_RS03985	COG1028	Short-chain dehydrogenase reductase Sdr
FIU86_RS04000	COG0601	transmembrane transport
FIU86_RS04005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIU86_RS04035	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FIU86_RS04045	COG1177	transmembrane transport
FIU86_RS04050	COG1176	ABC-type spermidine putrescine transport system, permease component I
FIU86_RS04055	COG3842	ATPase activity
FIU86_RS04075	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FIU86_RS04090	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FIU86_RS04095	COG0509	glycine decarboxylation via glycine cleavage system
FIU86_RS04100	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FIU86_RS04100	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FIU86_RS04105	COG0483	inositol monophosphate 1-phosphatase activity
FIU86_RS04115	COG4181	ATPase activity
FIU86_RS04125	COG1376	ErfK ybiS ycfS ynhG family protein
FIU86_RS04150	COG0488	(ABC) transporter
FIU86_RS04155	COG5001	Diguanylate cyclase
FIU86_RS04155	COG3300	MHYT domain
FIU86_RS04160	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FIU86_RS04245	COG0583	DNA-binding transcription factor activity
FIU86_RS04250	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FIU86_RS04255	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FIU86_RS04260	COG0424	maF-like protein
FIU86_RS04265	COG1530	ribonuclease E activity
FIU86_RS04270	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FIU86_RS04280	COG0270	DNA (cytosine-5-)-methyltransferase activity
FIU86_RS04285	COG3727	T/G mismatch-specific endonuclease activity
FIU86_RS04410	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIU86_RS04415	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FIU86_RS04420	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FIU86_RS04445	COG4607	ABC-type enterochelin transport system periplasmic component
FIU86_RS04450	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIU86_RS04455	COG4605	iron ion homeostasis
FIU86_RS04460	COG4604	ABC transporter, ATP-binding protein
FIU86_RS04465	COG4771	TonB-dependent receptor
FIU86_RS04475	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FIU86_RS04480	COG0840	transmembrane signaling receptor activity
FIU86_RS04490	COG0840	transmembrane signaling receptor activity
FIU86_RS04500	COG0745	RESPONSE REGULATOR receiver
FIU86_RS04505	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FIU86_RS04510	COG0835	chemotaxis
FIU86_RS04515	COG2198	Histidine kinase
FIU86_RS04515	COG0643	Histidine kinase
FIU86_RS04520	COG0745	RESPONSE REGULATOR receiver
FIU86_RS04530	COG0559	Belongs to the binding-protein-dependent transport system permease family
FIU86_RS04550	COG0318	PFAM AMP-dependent synthetase and ligase
FIU86_RS04555	COG1012	belongs to the aldehyde dehydrogenase family
FIU86_RS04580	COG0604	alcohol dehydrogenase
FIU86_RS04580	COG1028	Short-chain dehydrogenase reductase Sdr
FIU86_RS04580	COG3321	synthase
FIU86_RS04590	COG1028	Short-chain dehydrogenase reductase Sdr
FIU86_RS04610	COG1028	Short-chain dehydrogenase reductase Sdr
FIU86_RS04620	COG0318	PFAM AMP-dependent synthetase and ligase
FIU86_RS04635	COG4251	negative regulation of phosphorylation
FIU86_RS04655	COG0745	RESPONSE REGULATOR receiver
FIU86_RS04660	COG5002	protein histidine kinase activity
FIU86_RS04670	COG4999	Histidine kinase
FIU86_RS04670	COG3850	Histidine kinase
FIU86_RS04670	COG3437	response regulator, receiver
FIU86_RS04670	COG2205	protein histidine kinase activity
FIU86_RS04695	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FIU86_RS04705	COG0631	protein serine/threonine phosphatase activity
FIU86_RS04720	COG0745	RESPONSE REGULATOR receiver
FIU86_RS04730	COG0582	viral genome integration into host DNA
FIU86_RS04800	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FIU86_RS04810	COG1494	fructose-1,6-bisphosphatase
FIU86_RS04825	COG1309	transcriptional regulator
FIU86_RS04850	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FIU86_RS04860	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIU86_RS04870	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FIU86_RS04870	COG0446	pyridine nucleotide-disulphide oxidoreductase
FIU86_RS04890	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FIU86_RS04905	COG0432	Pfam Uncharacterised protein family UPF0047
FIU86_RS04910	COG4221	oxidoreductase activity
FIU86_RS04915	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FIU86_RS04920	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FIU86_RS04920	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FIU86_RS04930	COG2205	protein histidine kinase activity
FIU86_RS04935	COG0745	RESPONSE REGULATOR receiver
FIU86_RS04950	COG1012	belongs to the aldehyde dehydrogenase family
FIU86_RS04990	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FIU86_RS05000	COG1012	belongs to the aldehyde dehydrogenase family
FIU86_RS05005	COG0583	DNA-binding transcription factor activity
FIU86_RS05010	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FIU86_RS05015	COG1454	alcohol dehydrogenase
FIU86_RS05020	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FIU86_RS05045	COG0395	ABC-type sugar transport system, permease component
FIU86_RS05055	COG3842	ATPase activity
FIU86_RS05060	COG3842	ATPase activity
FIU86_RS05075	COG2202	Pas domain
FIU86_RS05075	COG3920	Histidine kinase
FIU86_RS05100	COG0583	DNA-binding transcription factor activity
FIU86_RS05105	COG4638	Rieske (2fe-2S)
FIU86_RS05110	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FIU86_RS05120	COG1028	Short-chain dehydrogenase reductase Sdr
FIU86_RS05125	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FIU86_RS05140	COG4176	ABC-type proline glycine betaine transport system permease component
FIU86_RS05150	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
FIU86_RS05155	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
FIU86_RS05165	COG1233	COG1233 Phytoene dehydrogenase and related
FIU86_RS05170	COG1562	ergosterol biosynthetic process
FIU86_RS05175	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FIU86_RS05185	COG5621	secreted hydrolase
FIU86_RS05190	COG1233	COG1233 Phytoene dehydrogenase and related
FIU86_RS05195	COG0142	geranyltranstransferase activity
FIU86_RS05200	COG0500	methyltransferase
FIU86_RS05205	COG1063	alcohol dehydrogenase
FIU86_RS05210	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
FIU86_RS05215	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FIU86_RS05220	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FIU86_RS05255	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FIU86_RS05260	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FIU86_RS05270	COG3474	cytochrome
FIU86_RS05275	COG0156	8-amino-7-oxononanoate synthase activity
FIU86_RS05285	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
FIU86_RS05320	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
FIU86_RS05325	COG1429	ligase activity, forming nitrogen-metal bonds
FIU86_RS05330	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FIU86_RS05335	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FIU86_RS05355	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FIU86_RS05360	COG2211	Major facilitator Superfamily
FIU86_RS05365	COG0644	oxidoreductase
FIU86_RS05375	COG1032	radical SAM domain protein
FIU86_RS05380	COG1719	4-vinyl reductase, 4VR
FIU86_RS05385	COG0583	DNA-binding transcription factor activity
FIU86_RS05390	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FIU86_RS05395	COG3383	formate dehydrogenase (NAD+) activity
FIU86_RS05400	COG1802	Transcriptional regulator
FIU86_RS05405	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FIU86_RS05415	COG1063	alcohol dehydrogenase
FIU86_RS05440	COG2308	Evidence 4 Homologs of previously reported genes of
FIU86_RS05445	COG0583	DNA-binding transcription factor activity
FIU86_RS05450	COG0346	lactoylglutathione lyase activity
FIU86_RS05455	COG0400	carboxylic ester hydrolase activity
FIU86_RS05460	COG1741	Belongs to the pirin family
FIU86_RS05465	COG1295	ribonuclease BN
FIU86_RS05490	COG1414	Transcriptional regulator
FIU86_RS05510	COG0714	Associated with various cellular activities
FIU86_RS05555	COG4999	Histidine kinase
FIU86_RS05555	COG2205	protein histidine kinase activity
FIU86_RS05555	COG3437	response regulator, receiver
FIU86_RS05555	COG3850	Histidine kinase
FIU86_RS05570	COG0535	radical SAM domain protein
FIU86_RS05575	COG0535	radical SAM domain protein
FIU86_RS05580	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
FIU86_RS05585	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FIU86_RS05595	COG0745	RESPONSE REGULATOR receiver
FIU86_RS05615	COG1131	(ABC) transporter
FIU86_RS05705	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FIU86_RS05730	COG0527	aspartate kinase activity
FIU86_RS05735	COG1917	Cupin 2, conserved barrel domain protein
FIU86_RS05740	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FIU86_RS05760	COG5002	protein histidine kinase activity
FIU86_RS05780	COG0745	RESPONSE REGULATOR receiver
FIU86_RS05785	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FIU86_RS05795	COG2022	thiamine diphosphate biosynthetic process
FIU86_RS05845	COG1233	COG1233 Phytoene dehydrogenase and related
FIU86_RS05865	COG1136	(ABC) transporter
FIU86_RS05880	COG3118	belongs to the thioredoxin family
FIU86_RS05915	COG1175	transmembrane transport
FIU86_RS05945	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FIU86_RS05950	COG0129	dihydroxy-acid dehydratase activity
FIU86_RS05955	COG0800	Aldolase
FIU86_RS05960	COG0166	Belongs to the GPI family
FIU86_RS06000	COG1686	Belongs to the peptidase S11 family
FIU86_RS06005	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FIU86_RS06015	COG0084	hydrolase, TatD family'
FIU86_RS06020	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FIU86_RS06020	COG0321	lipoyl(octanoyl) transferase activity
FIU86_RS06045	COG4948	Mandelate Racemase Muconate Lactonizing
FIU86_RS06075	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FIU86_RS06110	COG1047	Peptidyl-prolyl cis-trans
FIU86_RS06120	COG0604	alcohol dehydrogenase
FIU86_RS06130	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FIU86_RS06140	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FIU86_RS06145	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FIU86_RS06175	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FIU86_RS06180	COG2885	chlorophyll binding
FIU86_RS06190	COG1702	phosphate starvation-inducible protein PhoH
FIU86_RS06200	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FIU86_RS06210	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FIU86_RS06215	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FIU86_RS06225	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FIU86_RS06260	COG2274	protein secretion by the type I secretion system
FIU86_RS06275	COG3023	N-Acetylmuramoyl-L-alanine amidase
FIU86_RS06285	COG0154	amidase activity
FIU86_RS06290	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FIU86_RS06300	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FIU86_RS06305	COG0590	tRNA wobble adenosine to inosine editing
FIU86_RS06310	COG1187	pseudouridine synthase activity
FIU86_RS06315	COG4977	sequence-specific DNA binding
FIU86_RS06320	COG1490	D-aminoacyl-tRNA deacylase activity
FIU86_RS06335	COG3920	Histidine kinase
FIU86_RS06340	COG1610	YqeY-like protein
FIU86_RS06345	COG0505	Belongs to the CarA family
FIU86_RS06355	COG1802	Transcriptional regulator
FIU86_RS06380	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FIU86_RS06405	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FIU86_RS06415	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FIU86_RS06420	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FIU86_RS06425	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FIU86_RS06435	COG0583	DNA-binding transcription factor activity
FIU86_RS06445	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FIU86_RS06470	COG0740	serine-type endopeptidase activity
FIU86_RS06475	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FIU86_RS06495	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FIU86_RS06505	COG0439	Biotin carboxylase
FIU86_RS06510	COG0511	ligase activity, forming carbon-carbon bonds
FIU86_RS06515	COG0318	PFAM AMP-dependent synthetase and ligase
FIU86_RS06530	COG1396	sequence-specific DNA binding
FIU86_RS06535	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FIU86_RS06540	COG1846	Transcriptional regulator
FIU86_RS06555	COG3738	Protein conserved in bacteria
FIU86_RS06580	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FIU86_RS06610	COG0484	heat shock protein binding
FIU86_RS06640	COG1230	cation diffusion facilitator family transporter
FIU86_RS06670	COG1024	Enoyl-CoA hydratase
FIU86_RS06690	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIU86_RS06730	COG1937	Protein conserved in bacteria
FIU86_RS06785	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FIU86_RS06800	COG1278	Cold shock
FIU86_RS06805	COG1393	Belongs to the ArsC family
FIU86_RS06815	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FIU86_RS06855	COG3243	poly(R)-hydroxyalkanoic acid synthase
FIU86_RS06870	COG1376	ErfK ybiS ycfS ynhG family protein
FIU86_RS06885	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FIU86_RS06890	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIU86_RS06900	COG0174	glutamine synthetase
FIU86_RS06905	COG0519	Catalyzes the synthesis of GMP from XMP
FIU86_RS06910	COG0174	glutamine synthetase
FIU86_RS06915	COG3588	fructose-bisphosphate aldolase
FIU86_RS06930	COG0126	phosphoglycerate kinase activity
FIU86_RS06955	COG4215	(ABC) transporter
FIU86_RS06995	COG0504	CTP synthase activity
FIU86_RS07010	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FIU86_RS07025	COG0745	RESPONSE REGULATOR receiver
FIU86_RS07040	COG3118	belongs to the thioredoxin family
FIU86_RS07045	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FIU86_RS07050	COG2835	tetraacyldisaccharide 4'-kinase activity
FIU86_RS07055	COG2186	Transcriptional regulator
FIU86_RS07080	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FIU86_RS07085	COG0604	alcohol dehydrogenase
FIU86_RS07105	COG0275	rRNA processing
FIU86_RS07120	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FIU86_RS07130	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FIU86_RS07140	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FIU86_RS07150	COG2081	HI0933 family
FIU86_RS07155	COG5285	phytanoyl-CoA dioxygenase
FIU86_RS07165	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FIU86_RS07170	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FIU86_RS07175	COG0531	amino acid
FIU86_RS07190	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FIU86_RS07195	COG1181	Belongs to the D-alanine--D-alanine ligase family
FIU86_RS07200	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FIU86_RS07205	COG0849	cell division
FIU86_RS07210	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FIU86_RS07220	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FIU86_RS07225	COG0497	DNA recombination
FIU86_RS07230	COG0277	FAD linked oxidase domain protein
FIU86_RS07270	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FIU86_RS07275	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FIU86_RS07295	COG1519	Transferase
FIU86_RS07300	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FIU86_RS07320	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FIU86_RS07325	COG0546	phosphoglycolate phosphatase activity
FIU86_RS07330	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FIU86_RS07345	COG1960	acyl-CoA dehydrogenase activity
FIU86_RS07355	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FIU86_RS07370	COG3047	cAMP biosynthetic process
FIU86_RS07375	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FIU86_RS07385	COG0625	glutathione transferase activity
FIU86_RS07410	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FIU86_RS07415	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FIU86_RS07420	COG0649	NAD binding
FIU86_RS07475	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FIU86_RS07480	COG2226	methyltransferase
FIU86_RS07485	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FIU86_RS07500	COG0713	ATP synthesis coupled electron transport
FIU86_RS07515	COG1007	ATP synthesis coupled electron transport
FIU86_RS07525	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FIU86_RS07535	COG0513	Belongs to the DEAD box helicase family
FIU86_RS07565	COG1028	Short-chain dehydrogenase reductase Sdr
FIU86_RS07575	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FIU86_RS07580	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FIU86_RS07585	COG0805	protein transport
FIU86_RS07595	COG0739	heme binding
FIU86_RS07595	COG1388	LysM domain
FIU86_RS07600	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FIU86_RS07605	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FIU86_RS07610	COG4221	oxidoreductase activity
FIU86_RS07615	COG1268	BioY protein
FIU86_RS07630	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FIU86_RS07670	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FIU86_RS07675	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FIU86_RS07685	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FIU86_RS07690	COG0418	dihydroorotase activity
FIU86_RS07700	COG0542	response to heat
FIU86_RS07715	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FIU86_RS07750	COG0006	proline dipeptidase activity
FIU86_RS07755	COG0513	Belongs to the DEAD box helicase family
FIU86_RS07770	COG0739	heme binding
FIU86_RS07775	COG2833	Protein of unknown function (DUF455)
FIU86_RS07780	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FIU86_RS07790	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FIU86_RS07800	COG2814	Major facilitator Superfamily
FIU86_RS07810	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FIU86_RS07855	COG1960	acyl-CoA dehydrogenase activity
FIU86_RS07865	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FIU86_RS07870	COG2070	2-Nitropropane dioxygenase
FIU86_RS07885	COG0517	IMP dehydrogenase activity
FIU86_RS07885	COG0516	GMP reductase activity
FIU86_RS07890	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FIU86_RS07920	COG2354	Protein conserved in bacteria
FIU86_RS07925	COG2133	pyrroloquinoline quinone binding
FIU86_RS07930	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FIU86_RS07945	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FIU86_RS07950	COG0045	succinate-CoA ligase (ADP-forming) activity
FIU86_RS07980	COG1215	transferase activity, transferring glycosyl groups
FIU86_RS08000	COG0753	catalase activity
FIU86_RS08005	COG1012	belongs to the aldehyde dehydrogenase family
FIU86_RS08045	COG0174	glutamine synthetase
FIU86_RS08050	COG1012	belongs to the aldehyde dehydrogenase family
FIU86_RS08065	COG3842	ATPase activity
FIU86_RS08070	COG1176	ABC-type spermidine putrescine transport system, permease component I
FIU86_RS08075	COG1177	transmembrane transport
FIU86_RS08090	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FIU86_RS08100	COG1910	domain protein
FIU86_RS08140	COG1410	methionine synthase
FIU86_RS08140	COG0646	methionine synthase
FIU86_RS08155	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FIU86_RS08160	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FIU86_RS08165	COG0047	phosphoribosylformylglycinamidine synthase activity
FIU86_RS08175	COG2204	response regulator
FIU86_RS08180	COG1028	Short-chain dehydrogenase reductase Sdr
FIU86_RS08185	COG1530	ribonuclease E activity
FIU86_RS08190	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FIU86_RS08200	COG0425	Belongs to the sulfur carrier protein TusA family
FIU86_RS08205	COG0785	Cytochrome C biogenesis protein
FIU86_RS08235	COG0114	fumarate hydratase activity
FIU86_RS08245	COG2059	Chromate
FIU86_RS08270	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FIU86_RS08275	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FIU86_RS08280	COG0415	Belongs to the DNA photolyase family
FIU86_RS08285	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FIU86_RS08295	COG0494	nUDIX hydrolase
FIU86_RS08305	COG3264	Mechanosensitive ion channel
FIU86_RS08305	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FIU86_RS08315	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FIU86_RS08355	COG1566	PFAM secretion protein HlyD family protein
FIU86_RS08360	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIU86_RS08375	COG0446	pyridine nucleotide-disulphide oxidoreductase
FIU86_RS08375	COG1902	pentaerythritol trinitrate reductase activity
FIU86_RS08380	COG3938	Belongs to the proline racemase family
FIU86_RS08410	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FIU86_RS08410	COG3743	rRNA binding
FIU86_RS08415	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FIU86_RS08435	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FIU86_RS08440	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FIU86_RS08445	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FIU86_RS08480	COG1612	heme a metabolic process
FIU86_RS08515	COG3852	Histidine kinase
FIU86_RS08520	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FIU86_RS08530	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FIU86_RS08535	COG0594	ribonuclease P activity
FIU86_RS08540	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FIU86_RS08555	COG0010	Belongs to the arginase family
FIU86_RS08580	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FIU86_RS08590	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FIU86_RS08625	COG1217	gtp-binding protein TYPA
FIU86_RS08640	COG0629	single-stranded DNA binding
FIU86_RS08645	COG0739	heme binding
FIU86_RS08645	COG0741	lytic transglycosylase activity
FIU86_RS08645	COG1196	nuclear chromosome segregation
FIU86_RS08670	COG0528	UMP kinase activity
FIU86_RS08675	COG0233	cytoplasmic translational termination
FIU86_RS08680	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FIU86_RS08690	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FIU86_RS08695	COG0750	zinc metalloprotease
FIU86_RS08700	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FIU86_RS08710	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FIU86_RS08715	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FIU86_RS08720	COG3494	Protein of unknown function (DUF1009)
FIU86_RS08725	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FIU86_RS08730	COG1943	Transposase
FIU86_RS08735	COG0482	sulfurtransferase activity
FIU86_RS08750	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FIU86_RS08775	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FIU86_RS08780	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FIU86_RS08785	COG2264	protein methyltransferase activity
FIU86_RS08790	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FIU86_RS08795	COG1858	cytochrome C peroxidase
FIU86_RS08815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FIU86_RS08830	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FIU86_RS08835	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FIU86_RS08840	COG1309	transcriptional regulator
FIU86_RS08845	COG2326	polyphosphate kinase activity
FIU86_RS08855	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FIU86_RS08870	COG0697	spore germination
FIU86_RS08875	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FIU86_RS08875	COG0519	Catalyzes the synthesis of GMP from XMP
FIU86_RS08880	COG5598	trimethylamine methyltransferase
FIU86_RS08900	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FIU86_RS08910	COG2989	Protein conserved in bacteria
FIU86_RS08915	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FIU86_RS08935	COG0433	COG0433 Predicted ATPase
FIU86_RS08950	COG1722	exodeoxyribonuclease VII activity
FIU86_RS08955	COG0142	geranyltranstransferase activity
FIU86_RS08960	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FIU86_RS08985	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FIU86_RS08995	COG4166	transmembrane transport
FIU86_RS09000	COG1028	Short-chain dehydrogenase reductase Sdr
FIU86_RS09015	COG2313	pseudouridylate synthase activity
FIU86_RS09045	COG0052	Belongs to the universal ribosomal protein uS2 family
FIU86_RS09050	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FIU86_RS09065	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FIU86_RS09080	COG1960	acyl-CoA dehydrogenase activity
FIU86_RS09085	COG0583	DNA-binding transcription factor activity
FIU86_RS09090	COG0745	RESPONSE REGULATOR receiver
FIU86_RS09095	COG0704	Plays a role in the regulation of phosphate uptake
FIU86_RS09100	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FIU86_RS09110	COG0573	inorganic phosphate transmembrane transporter activity
FIU86_RS09130	COG0194	GDP metabolic process
FIU86_RS09135	COG1561	YicC-like family, N-terminal region
FIU86_RS09150	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FIU86_RS09155	COG1923	regulation of RNA biosynthetic process
FIU86_RS09160	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FIU86_RS09165	COG0569	domain protein
FIU86_RS09175	COG2204	response regulator
FIU86_RS09180	COG5000	phosphorelay sensor kinase activity
FIU86_RS09185	COG2204	response regulator
FIU86_RS09190	COG3852	Histidine kinase
FIU86_RS09195	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FIU86_RS09200	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FIU86_RS09200	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FIU86_RS09210	COG1546	Belongs to the CinA family
FIU86_RS09225	COG2867	negative regulation of translational initiation
FIU86_RS09245	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FIU86_RS09260	COG0719	Fe-S assembly protein
FIU86_RS09265	COG0396	ATPase activity
FIU86_RS09275	COG0393	Putative heavy-metal-binding
FIU86_RS09285	COG0719	Fe-S assembly protein
FIU86_RS09305	COG2945	thiolester hydrolase activity
FIU86_RS09325	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FIU86_RS09355	COG5425	PFAM Usg family protein
FIU86_RS09360	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FIU86_RS09385	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FIU86_RS09395	COG0488	(ABC) transporter
FIU86_RS09415	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FIU86_RS09420	COG0416	fatty acid biosynthetic process
FIU86_RS09425	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FIU86_RS09430	COG0776	regulation of translation
FIU86_RS09445	COG0717	Belongs to the dCTP deaminase family
FIU86_RS09455	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FIU86_RS09460	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FIU86_RS09465	COG1472	Belongs to the glycosyl hydrolase 3 family
FIU86_RS09475	COG0018	arginyl-trna synthetase
FIU86_RS09485	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FIU86_RS09490	COG0316	Belongs to the HesB IscA family
FIU86_RS09530	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FIU86_RS09555	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FIU86_RS09575	COG0697	spore germination
FIU86_RS09580	COG0148	phosphopyruvate hydratase activity
FIU86_RS09600	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FIU86_RS09605	COG0535	radical SAM domain protein
FIU86_RS09635	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FIU86_RS09650	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FIU86_RS09670	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIU86_RS09705	COG0028	Belongs to the TPP enzyme family
FIU86_RS09710	COG0440	acetolactate synthase activity
FIU86_RS09740	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FIU86_RS09750	COG0248	Ppx GppA phosphatase
FIU86_RS09760	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FIU86_RS09770	COG1295	ribonuclease BN
FIU86_RS09775	COG0589	response to stress
FIU86_RS09780	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIU86_RS09785	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FIU86_RS09790	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FIU86_RS09805	COG4166	transmembrane transport
FIU86_RS09815	COG3473	Maleate cis-trans isomerase
FIU86_RS09820	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FIU86_RS09825	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FIU86_RS09845	COG0798	PFAM Bile acid sodium symporter
FIU86_RS09850	COG0431	NADPH-dependent FMN reductase
FIU86_RS09855	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FIU86_RS09860	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FIU86_RS09870	COG4974	Belongs to the 'phage' integrase family
FIU86_RS09880	COG4536	flavin adenine dinucleotide binding
FIU86_RS09890	COG5012	cobalamin binding
FIU86_RS09905	COG2166	iron-sulfur cluster assembly
FIU86_RS09915	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FIU86_RS09920	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FIU86_RS09925	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FIU86_RS09985	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FIU86_RS10010	COG3932	Exopolysaccharide synthesis, ExoD
FIU86_RS10015	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FIU86_RS10025	COG0010	Belongs to the arginase family
FIU86_RS10035	COG2423	ornithine cyclodeaminase activity
FIU86_RS10045	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FIU86_RS10065	COG0259	pyridoxamine-phosphate oxidase activity
FIU86_RS10070	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FIU86_RS10080	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FIU86_RS10095	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FIU86_RS10125	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FIU86_RS10135	COG0315	cyclic pyranopterin monophosphate synthase activity
FIU86_RS10140	COG0303	'Molybdopterin
FIU86_RS10145	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FIU86_RS10150	COG2333	competence protein COMEC
FIU86_RS10150	COG0658	competence protein
FIU86_RS10155	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FIU86_RS10160	COG0372	Belongs to the citrate synthase family
FIU86_RS10175	COG1024	Enoyl-CoA hydratase
FIU86_RS10180	COG3088	subunit of a heme lyase
FIU86_RS10185	COG1138	Cytochrome C-type biogenesis protein
FIU86_RS10200	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FIU86_RS10205	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FIU86_RS10210	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FIU86_RS10225	COG0583	DNA-binding transcription factor activity
FIU86_RS10240	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FIU86_RS10250	COG0271	Belongs to the BolA IbaG family
FIU86_RS10260	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FIU86_RS10265	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIU86_RS10280	COG0069	glutamate synthase activity
FIU86_RS10285	COG2218	PFAM glutamate synthase alpha subunit domain protein
FIU86_RS10290	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FIU86_RS10300	COG0105	UTP biosynthetic process
FIU86_RS10305	COG0488	(ABC) transporter
FIU86_RS10310	COG2095	MarC family integral membrane protein
FIU86_RS10330	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FIU86_RS10345	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FIU86_RS10355	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FIU86_RS10360	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FIU86_RS10370	COG2890	protein-(glutamine-N5) methyltransferase activity
FIU86_RS10375	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FIU86_RS10390	COG0010	Belongs to the arginase family
FIU86_RS10395	COG1473	amidohydrolase
FIU86_RS10400	COG3956	TIGRFAM MazG family protein
FIU86_RS10410	COG0154	amidase activity
FIU86_RS10420	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FIU86_RS10425	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FIU86_RS10430	COG0860	N-Acetylmuramoyl-L-alanine amidase
FIU86_RS10440	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FIU86_RS10450	COG0156	8-amino-7-oxononanoate synthase activity
FIU86_RS10515	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FIU86_RS10520	COG0343	queuine tRNA-ribosyltransferase activity
FIU86_RS10540	COG4067	protein conserved in archaea
FIU86_RS10540	COG0189	ligase activity
FIU86_RS10545	COG2151	metal-sulfur cluster biosynthetic enzyme
FIU86_RS10560	COG0316	Belongs to the HesB IscA family
FIU86_RS10565	COG0149	triose-phosphate isomerase activity
FIU86_RS10570	COG1522	sequence-specific DNA binding
FIU86_RS10575	COG1648	precorrin-2 dehydrogenase activity
FIU86_RS10575	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FIU86_RS10585	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FIU86_RS10590	COG0175	sulfate reduction
FIU86_RS10610	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FIU86_RS10620	COG0601	transmembrane transport
FIU86_RS10625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIU86_RS10635	COG1473	amidohydrolase
FIU86_RS10640	COG4172	Belongs to the ABC transporter superfamily
FIU86_RS10650	COG2084	Dehydrogenase
FIU86_RS10710	COG2814	Major facilitator Superfamily
FIU86_RS10725	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FIU86_RS10730	COG0215	cysteine-tRNA ligase activity
FIU86_RS10750	COG1960	acyl-CoA dehydrogenase activity
FIU86_RS10765	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FIU86_RS10770	COG0508	dehydrogenase complex catalyzes the overall conversion of
FIU86_RS10770	COG0022	dehydrogenase e1 component
FIU86_RS10775	COG0508	dehydrogenase complex catalyzes the overall conversion of
FIU86_RS10815	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FIU86_RS10820	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FIU86_RS10825	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FIU86_RS10830	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FIU86_RS10840	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FIU86_RS10845	COG3038	cytochrome b561
FIU86_RS10850	COG2353	YceI-like domain
FIU86_RS10860	COG0360	Binds together with S18 to 16S ribosomal RNA
FIU86_RS10865	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FIU86_RS10870	COG0359	binds to the 23S rRNA
FIU86_RS10875	COG0544	peptidyl-prolyl cis-trans isomerase activity
FIU86_RS10970	COG3750	Belongs to the UPF0335 family
FIU86_RS10980	COG1024	Enoyl-CoA hydratase
FIU86_RS10980	COG1250	3-hydroxyacyl-CoA dehydrogenase
FIU86_RS11005	COG0745	RESPONSE REGULATOR receiver
FIU86_RS11010	COG3800	Transcriptional regulator
FIU86_RS11010	COG1396	sequence-specific DNA binding
FIU86_RS11035	COG0410	ABC transporter
FIU86_RS11040	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FIU86_RS11060	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FIU86_RS11065	COG0602	queuosine metabolic process
FIU86_RS11070	COG0720	synthase
FIU86_RS11075	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FIU86_RS11080	COG0534	Mate efflux family protein
FIU86_RS11095	COG2326	polyphosphate kinase activity
FIU86_RS11110	COG0556	nucleotide-excision repair
FIU86_RS11155	COG0697	spore germination
FIU86_RS11185	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FIU86_RS11190	COG1136	(ABC) transporter
FIU86_RS11205	COG0442	prolyl-tRNA aminoacylation
FIU86_RS11210	COG0628	permease
FIU86_RS11220	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FIU86_RS11225	COG0248	Ppx GppA phosphatase
FIU86_RS11240	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FIU86_RS11260	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FIU86_RS11260	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FIU86_RS11280	COG4770	biotin carboxylase activity
FIU86_RS11315	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FIU86_RS11325	COG2814	Major facilitator Superfamily
FIU86_RS11330	COG3800	Transcriptional regulator
FIU86_RS11330	COG1396	sequence-specific DNA binding
FIU86_RS11335	COG0747	negative chemotaxis
FIU86_RS11340	COG1309	transcriptional regulator
FIU86_RS11345	COG3119	arylsulfatase activity
FIU86_RS11350	COG0625	glutathione transferase activity
FIU86_RS11370	COG1960	acyl-CoA dehydrogenase activity
FIU86_RS11380	COG0483	inositol monophosphate 1-phosphatase activity
FIU86_RS11385	COG1396	sequence-specific DNA binding
FIU86_RS11390	COG1063	alcohol dehydrogenase
FIU86_RS11395	COG0583	DNA-binding transcription factor activity
FIU86_RS11405	COG0670	Belongs to the BI1 family
FIU86_RS11410	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FIU86_RS11415	COG3409	Peptidoglycan-binding domain 1 protein
FIU86_RS11415	COG3773	Cell wall hydrolase
FIU86_RS11420	COG0574	Belongs to the PEP-utilizing enzyme family
FIU86_RS11420	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FIU86_RS11425	COG0751	glycine-tRNA ligase activity
FIU86_RS11440	COG0752	glycyl-tRNA synthetase alpha subunit
FIU86_RS11460	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FIU86_RS11475	COG1469	GTP cyclohydrolase I activity
FIU86_RS11510	COG1285	pathogenesis
FIU86_RS11520	COG0552	protein localization to endoplasmic reticulum
FIU86_RS11525	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FIU86_RS11530	COG3239	Fatty acid desaturase
FIU86_RS11545	COG0693	protein deglycase activity
FIU86_RS11555	COG0151	Belongs to the GarS family
FIU86_RS11565	COG0587	DNA-directed DNA polymerase activity
FIU86_RS11585	COG0489	protein tyrosine kinase activity
FIU86_RS11595	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FIU86_RS11600	COG0217	transcriptional regulatory protein
FIU86_RS11610	COG0471	metal ion transport
FIU86_RS11610	COG3273	potassium ion transport
FIU86_RS11635	COG0471	metal ion transport
FIU86_RS11635	COG3273	potassium ion transport
FIU86_RS11645	COG1692	metallophosphoesterase
FIU86_RS11655	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FIU86_RS11660	COG2239	Acts as a magnesium transporter
FIU86_RS11665	COG0402	S-adenosylhomocysteine deaminase activity
FIU86_RS11680	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FIU86_RS11720	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FIU86_RS11725	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FIU86_RS11730	COG3842	ATPase activity
FIU86_RS11735	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FIU86_RS11745	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FIU86_RS11750	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FIU86_RS11755	COG4133	protoheme IX ABC transporter activity
FIU86_RS11760	COG3737	Protein of unknown function (DUF498/DUF598)
FIU86_RS11770	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FIU86_RS11775	COG1862	Preprotein translocase
FIU86_RS11785	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FIU86_RS11800	COG0006	proline dipeptidase activity
FIU86_RS11810	COG3239	Fatty acid desaturase
FIU86_RS11820	COG1160	GTP binding
FIU86_RS11855	COG5265	(ABC) transporter
FIU86_RS11875	COG2962	Rard protein
FIU86_RS11890	COG0446	pyridine nucleotide-disulphide oxidoreductase
FIU86_RS11890	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FIU86_RS11905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIU86_RS11910	COG4235	cytochrome complex assembly
FIU86_RS11915	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FIU86_RS11930	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FIU86_RS11945	COG4974	Belongs to the 'phage' integrase family
FIU86_RS11950	COG0517	IMP dehydrogenase activity
FIU86_RS11955	COG0583	DNA-binding transcription factor activity
FIU86_RS11960	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIU86_RS11970	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FIU86_RS11975	COG1028	Short-chain dehydrogenase reductase Sdr
FIU86_RS11980	COG3958	Transketolase
FIU86_RS11985	COG3959	Transketolase, thiamine diphosphate binding domain
FIU86_RS11990	COG0436	Aminotransferase
FIU86_RS12005	COG0656	L-ascorbic acid biosynthetic process
FIU86_RS12010	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FIU86_RS12015	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FIU86_RS12020	COG2080	2 iron, 2 sulfur cluster binding
FIU86_RS12045	COG2133	pyrroloquinoline quinone binding
FIU86_RS12070	COG1629	transport
FIU86_RS12075	COG3720	iron ion transport
FIU86_RS12080	COG4558	Periplasmic binding protein
FIU86_RS12085	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIU86_RS12090	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FIU86_RS12150	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIU86_RS12160	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FIU86_RS12165	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FIU86_RS12175	COG2986	histidine ammonia-lyase
FIU86_RS12180	COG1228	amidohydrolase
FIU86_RS12200	COG0735	belongs to the Fur family
FIU86_RS12205	COG1121	(ABC) transporter
FIU86_RS12210	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FIU86_RS12225	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FIU86_RS12240	COG0438	transferase activity, transferring glycosyl groups
FIU86_RS12265	COG2353	YceI-like domain
FIU86_RS12270	COG3246	L-lysine catabolic process to acetate
FIU86_RS12295	COG1397	ADP-ribosylglycohydrolase
FIU86_RS12300	COG0004	ammonium transporteR
FIU86_RS12320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIU86_RS12340	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FIU86_RS12345	COG0563	adenylate kinase activity
FIU86_RS12355	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FIU86_RS12370	COG2176	DNA-directed DNA polymerase activity
FIU86_RS12370	COG5002	protein histidine kinase activity
FIU86_RS12385	COG2995	paraquat-inducible protein a
FIU86_RS12390	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FIU86_RS12390	COG3008	intermembrane lipid transfer
FIU86_RS12405	COG0321	lipoyl(octanoyl) transferase activity
FIU86_RS12410	COG1764	response to oxidative stress
FIU86_RS12420	COG0210	DNA helicase
FIU86_RS12440	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FIU86_RS12445	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FIU86_RS12475	COG0131	Imidazoleglycerol-phosphate dehydratase
FIU86_RS12480	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FIU86_RS12495	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FIU86_RS12510	COG0107	imidazoleglycerol-phosphate synthase activity
FIU86_RS12515	COG0140	phosphoribosyl-ATP diphosphatase activity
FIU86_RS12525	COG1832	CoA-binding protein
FIU86_RS12535	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FIU86_RS12600	COG2873	o-acetylhomoserine
FIU86_RS12615	COG1329	Transcriptional regulator
FIU86_RS12620	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FIU86_RS12645	COG2267	carboxylic ester hydrolase activity
FIU86_RS12650	COG0179	Fumarylacetoacetate (FAA) hydrolase
FIU86_RS12660	COG0681	Belongs to the peptidase S26 family
FIU86_RS12665	COG1793	dna ligase
FIU86_RS12670	COG0006	proline dipeptidase activity
FIU86_RS12675	COG0583	DNA-binding transcription factor activity
FIU86_RS12690	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FIU86_RS12705	COG0564	pseudouridine synthase activity
FIU86_RS12745	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FIU86_RS12745	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FIU86_RS12750	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FIU86_RS12755	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FIU86_RS12770	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FIU86_RS12785	COG1028	Short-chain dehydrogenase reductase Sdr
FIU86_RS12810	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FIU86_RS12815	COG0308	aminopeptidase N
FIU86_RS12850	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FIU86_RS12860	COG2186	Transcriptional regulator
FIU86_RS12875	COG1178	ABC-type Fe3 transport system permease component
FIU86_RS12885	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FIU86_RS12890	COG4149	molybdate abc transporter
FIU86_RS12895	COG0725	ABC transporter, periplasmic molybdate-binding protein
FIU86_RS12915	COG0527	aspartate kinase activity
FIU86_RS12925	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FIU86_RS12945	COG0659	secondary active sulfate transmembrane transporter activity
FIU86_RS12950	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FIU86_RS13035	COG0667	Aldo Keto reductase
FIU86_RS13050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIU86_RS13070	COG2197	response regulator
FIU86_RS13095	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FIU86_RS13115	COG1522	sequence-specific DNA binding
FIU86_RS13120	COG0506	proline dehydrogenase activity
FIU86_RS13120	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FIU86_RS13120	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FIU86_RS13135	COG0483	inositol monophosphate 1-phosphatase activity
FIU86_RS13155	COG0525	valine-tRNA ligase activity
FIU86_RS13160	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FIU86_RS13170	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FIU86_RS13185	COG0354	folic acid binding
FIU86_RS13190	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FIU86_RS13215	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FIU86_RS13305	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FIU86_RS13310	COG0583	DNA-binding transcription factor activity
FIU86_RS13315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FIU86_RS13320	COG0765	amino acid transport
FIU86_RS13325	COG0765	amino acid transport
FIU86_RS13330	COG1126	abc transporter atp-binding protein
FIU86_RS13335	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FIU86_RS13340	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FIU86_RS13350	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FIU86_RS13355	COG0183	Belongs to the thiolase family
FIU86_RS13360	COG1473	amidohydrolase
FIU86_RS13385	COG0811	peptide transport
FIU86_RS13410	COG2116	formate transmembrane transporter activity
FIU86_RS13430	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FIU86_RS13445	COG0784	Response regulator, receiver
FIU86_RS13465	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FIU86_RS13470	COG3237	CsbD-like
FIU86_RS13475	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FIU86_RS13515	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FIU86_RS13530	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FIU86_RS13540	COG0124	histidyl-tRNA synthetase
FIU86_RS13560	COG3845	ABC transporter
FIU86_RS13565	COG4603	Belongs to the binding-protein-dependent transport system permease family
FIU86_RS13570	COG1079	Belongs to the binding-protein-dependent transport system permease family
FIU86_RS13590	COG3757	hydrolase, family 25
FIU86_RS13615	COG0405	Gamma-glutamyltransferase
FIU86_RS13655	COG3591	Belongs to the peptidase S1B family
FIU86_RS13670	COG2010	Cytochrome c
FIU86_RS13700	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FIU86_RS13705	COG0625	glutathione transferase activity
FIU86_RS13720	COG1012	belongs to the aldehyde dehydrogenase family
FIU86_RS13725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FIU86_RS13730	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FIU86_RS13735	COG2267	carboxylic ester hydrolase activity
FIU86_RS13745	COG0583	DNA-binding transcription factor activity
FIU86_RS13750	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FIU86_RS13760	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FIU86_RS13765	COG0189	ligase activity
FIU86_RS13765	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FIU86_RS13800	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FIU86_RS13820	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FIU86_RS13845	COG0444	Belongs to the ABC transporter superfamily
FIU86_RS13850	COG4608	Belongs to the ABC transporter superfamily
FIU86_RS13855	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FIU86_RS13870	COG0457	Tetratricopeptide repeat
FIU86_RS13950	COG0477	Major facilitator Superfamily
FIU86_RS13985	COG1012	belongs to the aldehyde dehydrogenase family
FIU86_RS13990	COG4638	Rieske (2fe-2S)
FIU86_RS14005	COG4948	Mandelate Racemase Muconate Lactonizing
FIU86_RS14010	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FIU86_RS14015	COG0438	transferase activity, transferring glycosyl groups
FIU86_RS14020	COG1216	Glycosyl transferase, family 2
FIU86_RS14050	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FIU86_RS14055	COG2197	response regulator
FIU86_RS14085	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FIU86_RS14095	COG1393	Belongs to the ArsC family
FIU86_RS14110	COG0737	Belongs to the 5'-nucleotidase family
FIU86_RS14120	COG2135	peptidase activity
FIU86_RS14130	COG0534	Mate efflux family protein
FIU86_RS14155	COG1960	acyl-CoA dehydrogenase activity
FIU86_RS14165	COG1960	acyl-CoA dehydrogenase activity
FIU86_RS14170	COG0625	glutathione transferase activity
FIU86_RS14175	COG0183	Belongs to the thiolase family
FIU86_RS14180	COG1250	3-hydroxyacyl-CoA dehydrogenase
FIU86_RS14180	COG1024	Enoyl-CoA hydratase
FIU86_RS14195	COG0318	PFAM AMP-dependent synthetase and ligase
FIU86_RS14210	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FIU86_RS14220	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FIU86_RS14230	COG0280	phosphate acetyltransferase
FIU86_RS14230	COG0281	malic enzyme
FIU86_RS14245	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FIU86_RS14250	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FIU86_RS14260	COG2267	carboxylic ester hydrolase activity
FIU86_RS14285	COG0481	GTPase activity
FIU86_RS14290	COG1254	Belongs to the acylphosphatase family
FIU86_RS14305	COG0842	Transport permease protein
FIU86_RS14335	COG0612	Peptidase, M16
FIU86_RS14345	COG3346	SURF1 family
FIU86_RS14355	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FIU86_RS14360	COG0109	protoheme IX farnesyltransferase activity
FIU86_RS14370	COG0312	modulator of DNA gyrase
FIU86_RS14380	COG0758	DNA mediated transformation
FIU86_RS14385	COG1754	DNA topoisomerase type I activity
FIU86_RS14385	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FIU86_RS14390	COG0741	lytic transglycosylase activity
FIU86_RS14410	COG4964	Belongs to the GSP D family
FIU86_RS14460	COG1201	RNA secondary structure unwinding
FIU86_RS14475	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FIU86_RS14480	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FIU86_RS14490	COG4106	trans-aconitate 2-methyltransferase activity
FIU86_RS14495	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FIU86_RS14500	COG0037	tRNA processing
FIU86_RS14510	COG2885	chlorophyll binding
FIU86_RS14515	COG0823	Involved in the tonB-independent uptake of proteins
FIU86_RS14530	COG0848	biopolymer transport protein
FIU86_RS14540	COG0824	Thioesterase
FIU86_RS14555	COG2255	four-way junction helicase activity
FIU86_RS14560	COG0632	four-way junction helicase activity
FIU86_RS14565	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FIU86_RS14580	COG2264	protein methyltransferase activity
FIU86_RS14590	COG2391	methyltransferase activity
FIU86_RS14605	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FIU86_RS14620	COG0459	protein refolding
FIU86_RS14625	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FIU86_RS14635	COG1703	isobutyryl-CoA mutase activity
FIU86_RS14645	COG1643	Atp-dependent helicase
FIU86_RS14655	COG0306	phosphate transporter
FIU86_RS14665	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FIU86_RS14670	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FIU86_RS14675	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FIU86_RS14685	COG0626	cystathionine gamma-synthase activity
FIU86_RS14710	COG1228	amidohydrolase
FIU86_RS14725	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FIU86_RS14730	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FIU86_RS14740	COG0071	Belongs to the small heat shock protein (HSP20) family
FIU86_RS14755	COG2030	dehydratase
FIU86_RS14770	COG0196	riboflavin kinase activity
FIU86_RS14775	COG2983	Belongs to the UPF0260 family
FIU86_RS14790	COG0596	Alpha beta hydrolase
FIU86_RS14805	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FIU86_RS14810	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FIU86_RS14815	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FIU86_RS14820	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FIU86_RS14840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FIU86_RS14855	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FIU86_RS14855	COG2885	chlorophyll binding
FIU86_RS14865	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FIU86_RS14880	COG0287	Prephenate dehydrogenase
FIU86_RS14885	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FIU86_RS14890	COG5310	Homospermidine synthase
FIU86_RS14895	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FIU86_RS14905	COG2212	antiporter activity
FIU86_RS14910	COG1863	multisubunit Na H antiporter MnhE subunit
FIU86_RS14915	COG0651	ATP synthesis coupled electron transport
FIU86_RS14920	COG1006	Multisubunit Na H antiporter MnhC subunit
FIU86_RS14925	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FIU86_RS14925	COG2111	Na H antiporter
FIU86_RS14960	COG5328	Belongs to the UPF0262 family
FIU86_RS14970	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FIU86_RS14985	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FIU86_RS15010	COG0768	penicillin binding
FIU86_RS15015	COG0772	Belongs to the SEDS family
FIU86_RS15020	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FIU86_RS15030	COG1573	uracil-dna glycosylase
FIU86_RS15035	COG1335	isochorismatase
FIU86_RS15045	COG1054	Belongs to the UPF0176 family
FIU86_RS15050	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FIU86_RS15050	COG0517	IMP dehydrogenase activity
FIU86_RS15085	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FIU86_RS15090	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FIU86_RS15100	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FIU86_RS15120	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FIU86_RS15125	COG0517	IMP dehydrogenase activity
FIU86_RS15125	COG1994	Peptidase M50
FIU86_RS15130	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FIU86_RS15135	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FIU86_RS15170	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FIU86_RS15200	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FIU86_RS15225	COG0540	Belongs to the ATCase OTCase family
FIU86_RS15230	COG1573	uracil-dna glycosylase
FIU86_RS15240	COG0521	Mo-molybdopterin cofactor biosynthetic process
FIU86_RS15245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIU86_RS15260	COG1678	Uncharacterized ACR, COG1678
FIU86_RS15270	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIU86_RS15345	COG1403	HNH endonuclease
FIU86_RS15370	COG0012	GTP binding
FIU86_RS15375	COG0159	tryptophan synthase activity
FIU86_RS15385	COG1304	FMN binding
FIU86_RS15400	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FIU86_RS15410	COG0193	aminoacyl-tRNA hydrolase activity
FIU86_RS15435	COG0133	tryptophan synthase activity
FIU86_RS15450	COG0135	phosphoribosylanthranilate isomerase activity
FIU86_RS15460	COG0776	regulation of translation
FIU86_RS15465	COG0539	negative regulation of cytoplasmic translation
FIU86_RS15475	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FIU86_RS15495	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FIU86_RS15500	COG0251	oxidation-reduction process
FIU86_RS15510	COG1435	thymidine kinase activity
FIU86_RS15535	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FIU86_RS15540	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FIU86_RS15545	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FIU86_RS15560	COG2304	oxidoreductase activity
FIU86_RS15570	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FIU86_RS15580	COG1496	oxidoreductase activity
FIU86_RS15610	COG1522	sequence-specific DNA binding
FIU86_RS15615	COG0492	ferredoxin-NADP+ reductase activity
FIU86_RS15625	COG0583	DNA-binding transcription factor activity
FIU86_RS15630	COG0529	Catalyzes the synthesis of activated sulfate
FIU86_RS15630	COG2046	Belongs to the sulfate adenylyltransferase family
FIU86_RS15640	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FIU86_RS15660	COG1183	phosphatidylcholine synthase activity
FIU86_RS15685	COG1546	Belongs to the CinA family
FIU86_RS15685	COG1058	Belongs to the CinA family
FIU86_RS15690	COG1489	DNA binding
FIU86_RS15695	COG0024	Methionine aminopeptidase
FIU86_RS15700	COG3135	benzoate transporter
FIU86_RS15710	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FIU86_RS15725	COG3768	UPF0283 membrane protein
FIU86_RS15735	COG3106	COG3106 Predicted ATPase
FIU86_RS15740	COG0101	tRNA pseudouridine synthase activity
FIU86_RS15780	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FIU86_RS15785	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FIU86_RS15785	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FIU86_RS15830	COG1959	2 iron, 2 sulfur cluster binding
FIU86_RS15835	COG0450	alkyl hydroperoxide reductase
FIU86_RS15845	COG1271	oxidase subunit
FIU86_RS15850	COG1294	oxidase, subunit
FIU86_RS15940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIU86_RS15950	COG3246	L-lysine catabolic process to acetate
FIU86_RS15955	COG1028	Short-chain dehydrogenase reductase Sdr
FIU86_RS15970	COG1250	3-hydroxyacyl-CoA dehydrogenase
FIU86_RS15970	COG0824	Thioesterase
FIU86_RS15975	COG1960	acyl-CoA dehydrogenase activity
FIU86_RS15985	COG1024	Enoyl-CoA hydratase
FIU86_RS15990	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIU86_RS15995	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FIU86_RS16000	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FIU86_RS16020	COG2205	protein histidine kinase activity
FIU86_RS16045	COG2391	methyltransferase activity
FIU86_RS16050	COG0156	8-amino-7-oxononanoate synthase activity
FIU86_RS16060	COG0446	pyridine nucleotide-disulphide oxidoreductase
FIU86_RS16080	COG0737	Belongs to the 5'-nucleotidase family
FIU86_RS16085	COG3258	Cytochrome c
FIU86_RS16110	COG0785	Cytochrome C biogenesis protein
FIU86_RS16125	COG2391	methyltransferase activity
FIU86_RS16130	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FIU86_RS16135	COG1012	belongs to the aldehyde dehydrogenase family
FIU86_RS16140	COG1522	sequence-specific DNA binding
FIU86_RS16145	COG2423	ornithine cyclodeaminase activity
FIU86_RS16150	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FIU86_RS16160	COG3800	Transcriptional regulator
FIU86_RS16160	COG1396	sequence-specific DNA binding
FIU86_RS16185	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FIU86_RS16190	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FIU86_RS16195	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FIU86_RS16205	COG1802	Transcriptional regulator
FIU86_RS16210	COG1335	isochorismatase
FIU86_RS16215	COG0045	succinate-CoA ligase (ADP-forming) activity
FIU86_RS16230	COG0045	succinate-CoA ligase (ADP-forming) activity
FIU86_RS16235	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FIU86_RS16245	COG2072	flavoprotein involved in K transport
FIU86_RS16250	COG4638	Rieske (2fe-2S)
FIU86_RS16270	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FIU86_RS16275	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FIU86_RS16280	COG0830	nickel cation binding
FIU86_RS16285	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FIU86_RS16290	COG0804	urea catabolic process
FIU86_RS16295	COG0832	Belongs to the urease beta subunit family
FIU86_RS16305	COG0831	urea catabolic process
FIU86_RS16310	COG0829	nickel cation binding
FIU86_RS16335	COG1172	Belongs to the binding-protein-dependent transport system permease family
FIU86_RS16355	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FIU86_RS16365	COG0583	DNA-binding transcription factor activity
FIU86_RS16375	COG1176	ABC-type spermidine putrescine transport system, permease component I
FIU86_RS16385	COG3842	ATPase activity
FIU86_RS16400	COG1960	acyl-CoA dehydrogenase activity
FIU86_RS16415	COG0427	acetyl-CoA hydrolase
FIU86_RS16425	COG0318	PFAM AMP-dependent synthetase and ligase
FIU86_RS16440	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FIU86_RS16440	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIU86_RS16445	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FIU86_RS16455	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FIU86_RS16460	COG2358	TRAP transporter, solute receptor (TAXI family
FIU86_RS16475	COG0571	ribonuclease III activity
FIU86_RS16480	COG0681	Belongs to the peptidase S26 family
FIU86_RS16485	COG0736	holo-[acyl-carrier-protein] synthase activity
FIU86_RS16510	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FIU86_RS16520	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FIU86_RS16525	COG1758	RNA polymerase activity
FIU86_RS16530	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FIU86_RS16540	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FIU86_RS16550	COG4589	Belongs to the CDS family
FIU86_RS16570	COG2226	methyltransferase
FIU86_RS16575	COG0328	RNA-DNA hybrid ribonuclease activity
FIU86_RS16580	COG2860	membrane
FIU86_RS16595	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FIU86_RS16600	COG0242	peptide deformylase activity
FIU86_RS16605	COG0242	peptide deformylase activity
FIU86_RS16610	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FIU86_RS16630	COG0435	Glutathione S-transferase
FIU86_RS16635	COG0840	transmembrane signaling receptor activity
FIU86_RS16645	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FIU86_RS16660	COG0318	PFAM AMP-dependent synthetase and ligase
FIU86_RS16675	COG2217	Heavy metal translocating P-type atpase
FIU86_RS16690	COG2124	cytochrome p450
FIU86_RS16695	COG5598	trimethylamine methyltransferase
FIU86_RS16705	COG1012	belongs to the aldehyde dehydrogenase family
FIU86_RS16710	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FIU86_RS16725	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FIU86_RS16735	COG0069	glutamate synthase activity
FIU86_RS16745	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FIU86_RS16755	COG2186	Transcriptional regulator
FIU86_RS16765	COG0181	hydroxymethylbilane synthase activity
FIU86_RS16770	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FIU86_RS16780	COG0006	proline dipeptidase activity
FIU86_RS16810	COG0116	Belongs to the methyltransferase superfamily
FIU86_RS16845	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIU86_RS16870	COG2186	Transcriptional regulator
FIU86_RS16900	COG1309	transcriptional regulator
FIU86_RS16930	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FIU86_RS16935	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FIU86_RS16945	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FIU86_RS16950	COG0569	domain protein
FIU86_RS16955	COG1686	Belongs to the peptidase S11 family
FIU86_RS16975	COG0348	domain, Protein
FIU86_RS16980	COG0583	DNA-binding transcription factor activity
FIU86_RS16990	COG2010	Cytochrome c
FIU86_RS17020	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FIU86_RS17035	COG0697	spore germination
FIU86_RS17040	COG0463	Glycosyl transferase, family 2
FIU86_RS17045	COG0747	negative chemotaxis
FIU86_RS17055	COG0517	IMP dehydrogenase activity
FIU86_RS17060	COG4974	Belongs to the 'phage' integrase family
FIU86_RS17065	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FIU86_RS17070	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FIU86_RS17085	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FIU86_RS17100	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FIU86_RS17115	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FIU86_RS17120	COG0142	geranyltranstransferase activity
FIU86_RS17140	COG0583	DNA-binding transcription factor activity
FIU86_RS17145	COG1028	Short-chain dehydrogenase reductase Sdr
FIU86_RS17160	COG2200	EAL domain
FIU86_RS17160	COG2771	luxR family
FIU86_RS17165	COG2818	Glycosylase
FIU86_RS17170	COG0129	dihydroxy-acid dehydratase activity
FIU86_RS17205	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FIU86_RS17225	COG0450	alkyl hydroperoxide reductase
FIU86_RS17250	COG0564	pseudouridine synthase activity
FIU86_RS17275	COG1280	lysine exporter protein (LysE YggA)
FIU86_RS17300	COG1280	lysine exporter protein (LysE YggA)
FIU86_RS17315	COG1956	GAF domain-containing protein
FIU86_RS17320	COG0183	Belongs to the thiolase family
FIU86_RS17325	COG1366	Belongs to the anti-sigma-factor antagonist family
FIU86_RS17335	COG0405	Gamma-glutamyltransferase
FIU86_RS17350	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FIU86_RS17355	COG3932	Exopolysaccharide synthesis, ExoD
FIU86_RS17360	COG1674	ftsk spoiiie
FIU86_RS17365	COG0436	Aminotransferase
FIU86_RS17375	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FIU86_RS17380	COG0742	ribosomal rna small subunit methyltransferase
FIU86_RS17390	COG0678	peroxiredoxin activity
FIU86_RS17395	COG2154	pterin-4-alpha-carbinolamine dehydratase
FIU86_RS17405	COG0584	glycerophosphoryl diester phosphodiesterase
FIU86_RS17410	COG0251	oxidation-reduction process
FIU86_RS17415	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIU86_RS17420	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FIU86_RS17425	COG2853	Lipoprotein
FIU86_RS17440	COG0347	Belongs to the P(II) protein family
FIU86_RS17445	COG0004	ammonium transporteR
FIU86_RS17455	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FIU86_RS17460	COG0285	dihydrofolate synthase activity
FIU86_RS17475	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FIU86_RS17485	COG1115	amino acid carrier protein
FIU86_RS17495	COG3920	Histidine kinase
FIU86_RS17515	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FIU86_RS17525	COG0776	regulation of translation
FIU86_RS17530	COG0697	spore germination
FIU86_RS17535	COG2226	methyltransferase
FIU86_RS17540	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FIU86_RS17555	COG1271	oxidase subunit
FIU86_RS17560	COG1294	oxidase, subunit
FIU86_RS17585	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FIU86_RS17590	COG1321	iron dependent repressor
FIU86_RS17590	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FIU86_RS17595	COG1121	(ABC) transporter
FIU86_RS17600	COG0803	Belongs to the bacterial solute-binding protein 9 family
FIU86_RS17605	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
FIU86_RS17635	COG0438	transferase activity, transferring glycosyl groups
FIU86_RS17635	COG1216	Glycosyl transferase, family 2
FIU86_RS17675	COG0662	Cupin 2, conserved barrel domain protein
FIU86_RS17675	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FIU86_RS17735	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FIU86_RS17755	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FIU86_RS17785	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
FIU86_RS17790	COG0300	oxidoreductase activity
FIU86_RS17820	COG0702	epimerase
FIU86_RS17835	COG0673	inositol 2-dehydrogenase activity
FIU86_RS17875	COG1596	polysaccharide export
FIU86_RS17880	COG3267	Type II secretory pathway component ExeA
FIU86_RS17880	COG3409	Peptidoglycan-binding domain 1 protein
FIU86_RS17890	COG0489	protein tyrosine kinase activity
FIU86_RS17905	COG2076	Multidrug Resistance protein
FIU86_RS17960	COG1609	Transcriptional regulator
FIU86_RS17975	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FIU86_RS17990	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FIU86_RS17995	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FIU86_RS18005	COG0356	it plays a direct role in the translocation of protons across the membrane
FIU86_RS18025	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FIU86_RS18050	COG0228	four-way junction DNA binding
FIU86_RS18055	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FIU86_RS18065	COG0336	Belongs to the RNA methyltransferase TrmD family
FIU86_RS18075	COG0335	large ribosomal subunit rRNA binding
FIU86_RS18080	COG0254	rRNA binding
FIU86_RS18085	COG0489	protein tyrosine kinase activity
FIU86_RS18085	COG2151	metal-sulfur cluster biosynthetic enzyme
FIU86_RS18115	COG4953	penicillin-binding protein 1C
FIU86_RS18120	COG0183	Belongs to the thiolase family
FIU86_RS18135	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FIU86_RS18155	COG4143	(ABC) transporter
FIU86_RS18165	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FIU86_RS18185	COG0009	L-threonylcarbamoyladenylate synthase
FIU86_RS18190	COG1960	acyl-CoA dehydrogenase activity
FIU86_RS18220	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FIU86_RS18230	COG0746	molybdenum cofactor guanylyltransferase activity
FIU86_RS18240	COG0303	'Molybdopterin
FIU86_RS18245	COG1132	(ABC) transporter
FIU86_RS18270	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FIU86_RS18280	COG1129	ABC transporter
FIU86_RS18290	COG0559	Belongs to the binding-protein-dependent transport system permease family
FIU86_RS18325	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FIU86_RS18340	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FIU86_RS18345	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FIU86_RS18355	COG1012	belongs to the aldehyde dehydrogenase family
FIU86_RS18365	COG0469	pyruvate kinase activity
FIU86_RS18400	COG4948	Mandelate Racemase Muconate Lactonizing
FIU86_RS18410	COG2301	Belongs to the HpcH HpaI aldolase family
FIU86_RS18430	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
FIU86_RS18435	COG2943	transferase activity, transferring hexosyl groups
FIU86_RS18445	COG3622	Belongs to the hyi family
FIU86_RS18465	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FIU86_RS18480	COG1215	transferase activity, transferring glycosyl groups
FIU86_RS18500	COG0456	acetyltransferase
FIU86_RS18505	COG0473	3-isopropylmalate dehydrogenase activity
FIU86_RS18530	COG0066	3-isopropylmalate dehydratase activity
FIU86_RS18535	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FIU86_RS18545	COG0745	RESPONSE REGULATOR receiver
FIU86_RS18550	COG1846	Transcriptional regulator
FIU86_RS18555	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FIU86_RS18580	COG3842	ATPase activity
FIU86_RS18585	COG0006	proline dipeptidase activity
FIU86_RS18610	COG3842	ATPase activity
FIU86_RS18615	COG1176	ABC-type spermidine putrescine transport system, permease component I
FIU86_RS18620	COG1177	transmembrane transport
FIU86_RS18625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIU86_RS18635	COG0386	Belongs to the glutathione peroxidase family
FIU86_RS18645	COG1063	alcohol dehydrogenase
FIU86_RS18665	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FIU86_RS18675	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FIU86_RS18690	COG1968	undecaprenyl-diphosphatase activity
FIU86_RS18725	COG4608	Belongs to the ABC transporter superfamily
FIU86_RS18755	COG1609	Transcriptional regulator
FIU86_RS18765	COG1012	belongs to the aldehyde dehydrogenase family
FIU86_RS18770	COG2084	Dehydrogenase
FIU86_RS18775	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FIU86_RS18810	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FIU86_RS18820	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FIU86_RS18830	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FIU86_RS18835	COG1999	signal sequence binding
FIU86_RS18850	COG0802	atpase or kinase
FIU86_RS18855	COG3178	'Phosphotransferase
FIU86_RS18860	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FIU86_RS18870	COG1074	ATP-dependent DNA helicase activity
FIU86_RS18880	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FIU86_RS18885	COG2267	carboxylic ester hydrolase activity
FIU86_RS18895	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FIU86_RS18930	COG3030	protein affecting phage T7 exclusion by the F plasmid
FIU86_RS18935	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FIU86_RS18940	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FIU86_RS18945	COG0237	dephospho-CoA kinase activity
FIU86_RS18950	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FIU86_RS18955	COG0424	maF-like protein
FIU86_RS18960	COG1981	membrane
FIU86_RS18965	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FIU86_RS18970	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FIU86_RS18975	COG0445	tRNA wobble uridine modification
FIU86_RS18980	COG0357	Ribosomal RNA small subunit methyltransferase G
FIU86_RS18995	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FIU86_RS19000	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FIU86_RS19005	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FIU86_RS19010	COG1420	regulation of RNA biosynthetic process
FIU86_RS19015	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FIU86_RS19020	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FIU86_RS19030	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FIU86_RS19045	COG0137	argininosuccinate synthase activity
FIU86_RS19050	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FIU86_RS19065	COG0494	nUDIX hydrolase
FIU86_RS19075	COG0494	nUDIX hydrolase
FIU86_RS19080	COG0617	tRNA 3'-terminal CCA addition
FIU86_RS19085	COG1132	(ABC) transporter
FIU86_RS19090	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FIU86_RS19095	COG3034	peptidoglycan biosynthetic process
FIU86_RS19115	COG2226	methyltransferase
FIU86_RS19120	COG1040	competence protein
FIU86_RS19130	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FIU86_RS19140	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FIU86_RS19150	COG0779	Required for maturation of 30S ribosomal subunits
FIU86_RS19160	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FIU86_RS19165	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FIU86_RS19170	COG0494	nUDIX hydrolase
FIU86_RS19175	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FIU86_RS19180	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FIU86_RS19185	COG0653	protein targeting
FIU86_RS19220	COG0667	Aldo Keto reductase
FIU86_RS19230	COG1418	mRNA catabolic process
FIU86_RS19260	COG0697	spore germination
FIU86_RS19270	COG1181	Belongs to the D-alanine--D-alanine ligase family
FIU86_RS19280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FIU86_RS19285	COG2814	Major facilitator Superfamily
FIU86_RS19295	COG0583	DNA-binding transcription factor activity
FIU86_RS19320	COG3846	protein secretion by the type IV secretion system
FIU86_RS19335	COG3451	type IV secretory pathway VirB4
FIU86_RS19350	COG4962	Type ii secretion system protein e
FIU86_RS19370	COG1028	Short-chain dehydrogenase reductase Sdr
FIU86_RS19380	COG0741	lytic transglycosylase activity
FIU86_RS19405	COG1192	Involved in chromosome partitioning
FIU86_RS19435	COG5489	Protein of unknown function (DUF736)
FIU86_RS19505	COG0419	ATPase involved in DNA repair
FIU86_RS19520	COG1396	sequence-specific DNA binding
FIU86_RS19545	COG0582	viral genome integration into host DNA
FIU86_RS19550	COG2003	Belongs to the UPF0758 family
FIU86_RS19555	COG0484	heat shock protein binding
FIU86_RS19560	COG0443	Heat shock 70 kDa protein
FIU86_RS19585	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FIU86_RS19590	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FIU86_RS19595	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FIU86_RS19620	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIU86_RS19625	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FIU86_RS19630	COG1137	ATPase activity
FIU86_RS19635	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FIU86_RS19645	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FIU86_RS19670	COG0523	cobalamin synthesis protein
FIU86_RS19685	COG0747	negative chemotaxis
FIU86_RS19690	COG0601	transmembrane transport
FIU86_RS19695	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIU86_RS19700	COG4172	Belongs to the ABC transporter superfamily
FIU86_RS19710	COG0577	efflux transmembrane transporter activity
FIU86_RS19710	COG1136	(ABC) transporter
FIU86_RS19750	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FIU86_RS19755	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FIU86_RS19790	COG1706	bacterial-type flagellum-dependent cell motility
FIU86_RS19795	COG1338	Plays a role in the flagellum-specific transport system
FIU86_RS19800	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FIU86_RS19810	COG1766	The M ring may be actively involved in energy transduction
FIU86_RS19830	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FIU86_RS19840	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FIU86_RS19845	COG1684	flagellar biosynthetic protein fliR
FIU86_RS19850	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FIU86_RS19865	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FIU86_RS19875	COG4786	Flagellar basal body rod
FIU86_RS19880	COG4786	Flagellar basal body rod
FIU86_RS19885	COG1987	bacterial-type flagellum assembly
FIU86_RS19890	COG1677	Flagellar hook-basal body complex protein FliE
FIU86_RS19895	COG1558	bacterial-type flagellum-dependent cell motility
FIU86_RS19900	COG1815	bacterial-type flagellum-dependent cell motility
FIU86_RS19915	COG5443	negative regulation of bacterial-type flagellum assembly
FIU86_RS19945	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FIU86_RS19960	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FIU86_RS19970	COG2226	methyltransferase
FIU86_RS19975	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FIU86_RS19980	COG1024	Enoyl-CoA hydratase
FIU86_RS19985	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FIU86_RS19990	COG0583	DNA-binding transcription factor activity
FIU86_RS19995	COG0268	Binds directly to 16S ribosomal RNA
FIU86_RS20000	COG1192	Involved in chromosome partitioning
FIU86_RS20005	COG1475	DNA binding
FIU86_RS20010	COG0640	Transcriptional regulator
FIU86_RS20050	COG1846	Transcriptional regulator
FIU86_RS20085	COG0583	DNA-binding transcription factor activity
FIU86_RS20105	COG5002	protein histidine kinase activity
FIU86_RS20125	COG3609	addiction module antidote protein, CC2985 family
FIU86_RS20185	COG4962	Type ii secretion system protein e
FIU86_RS20210	COG0739	heme binding
FIU86_RS20210	COG1196	nuclear chromosome segregation
FIU86_RS20210	COG0741	lytic transglycosylase activity
FIU86_RS20230	COG0741	lytic transglycosylase activity
FIU86_RS20230	COG1196	nuclear chromosome segregation
FIU86_RS20230	COG0739	heme binding
FIU86_RS20265	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FIU86_RS20265	COG0617	tRNA 3'-terminal CCA addition
FIU86_RS20265	COG0517	IMP dehydrogenase activity
FIU86_RS20325	COG2801	Transposase and inactivated derivatives
FIU86_RS20355	COG0789	Transcriptional regulator
FIU86_RS20365	COG4232	protein-disulfide reductase activity
FIU86_RS20370	COG4235	cytochrome complex assembly
FIU86_RS20375	COG3088	subunit of a heme lyase
FIU86_RS20380	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FIU86_RS20385	COG1138	Cytochrome C-type biogenesis protein
FIU86_RS20430	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FIU86_RS20435	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FIU86_RS20440	COG2366	antibiotic biosynthetic process
FIU86_RS20450	COG1999	signal sequence binding
FIU86_RS20460	COG1321	iron dependent repressor
FIU86_RS20485	COG3034	peptidoglycan biosynthetic process
FIU86_RS20535	COG2132	Multicopper oxidase
FIU86_RS20550	COG0398	Pfam SNARE associated Golgi protein
FIU86_RS20560	COG0531	amino acid
FIU86_RS20565	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FIU86_RS20675	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FIU86_RS20675	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FIU86_RS20745	COG0785	Cytochrome C biogenesis protein
FIU86_RS20765	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FIU86_RS20770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FIU86_RS20785	COG2132	Multicopper oxidase
FIU86_RS20810	COG0789	Transcriptional regulator
FIU86_RS20815	COG1999	signal sequence binding
FIU86_RS20825	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FIU86_RS20825	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FIU86_RS20835	COG1999	signal sequence binding
FIU86_RS20860	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FIU86_RS20865	COG3034	peptidoglycan biosynthetic process
FIU86_RS20885	COG2132	Multicopper oxidase
FIU86_RS20895	COG0398	Pfam SNARE associated Golgi protein
FIU86_RS20905	COG1376	ErfK ybiS ycfS ynhG family protein
FIU86_RS20955	COG1917	Cupin 2, conserved barrel domain protein
FIU86_RS20955	COG1396	sequence-specific DNA binding
FIU86_RS20960	COG0446	pyridine nucleotide-disulphide oxidoreductase
FIU86_RS20960	COG1902	pentaerythritol trinitrate reductase activity
FIU86_RS20970	COG5383	Protein conserved in bacteria
FIU86_RS20975	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIU86_RS20980	COG1012	belongs to the aldehyde dehydrogenase family
FIU86_RS20985	COG0436	Aminotransferase
FIU86_RS21015	COG0583	DNA-binding transcription factor activity
FIU86_RS21020	COG2814	Major facilitator Superfamily
FIU86_RS21025	COG0656	L-ascorbic acid biosynthetic process
FIU86_RS21075	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FIU86_RS21100	COG1192	Involved in chromosome partitioning
FIU86_RS21160	COG3621	Patatin-like phospholipase
FIU86_RS21205	COG0556	nucleotide-excision repair
FIU86_RS21275	COG3189	MarR family transcriptional regulator
FIU86_RS21280	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FIU86_RS21285	COG0583	DNA-binding transcription factor activity
FIU86_RS21290	COG0517	IMP dehydrogenase activity
FIU86_RS21290	COG0617	tRNA 3'-terminal CCA addition
FIU86_RS21290	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FIU86_RS21305	COG1028	Short-chain dehydrogenase reductase Sdr
FIU86_RS21310	COG1028	Short-chain dehydrogenase reductase Sdr
FIU86_RS21330	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FIU86_RS21335	COG1116	anion transmembrane transporter activity
FIU86_RS21335	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FIU86_RS21365	COG1028	Short-chain dehydrogenase reductase Sdr
FIU86_RS21370	COG1028	Short-chain dehydrogenase reductase Sdr
FIU86_RS21375	COG1250	3-hydroxyacyl-CoA dehydrogenase
FIU86_RS21380	COG1012	belongs to the aldehyde dehydrogenase family
FIU86_RS21385	COG3246	L-lysine catabolic process to acetate
FIU86_RS21390	COG3119	arylsulfatase activity
FIU86_RS21395	COG4638	Rieske (2fe-2S)
FIU86_RS21410	COG4175	Glycine betaine
FIU86_RS21410	COG0517	IMP dehydrogenase activity
FIU86_RS21415	COG4176	ABC-type proline glycine betaine transport system permease component
FIU86_RS21425	COG0477	Major facilitator Superfamily
FIU86_RS21440	COG1126	abc transporter atp-binding protein
FIU86_RS21455	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FIU86_RS21485	COG2315	Protein conserved in bacteria
FIU86_RS21495	COG0747	negative chemotaxis
FIU86_RS21510	COG1733	regulation of RNA biosynthetic process
FIU86_RS21520	COG0625	glutathione transferase activity
FIU86_RS21550	COG1192	Involved in chromosome partitioning
FIU86_RS21555	COG1475	DNA binding
FIU86_RS21560	COG1414	Transcriptional regulator
FIU86_RS21565	COG3609	addiction module antidote protein, CC2985 family
FIU86_RS21625	COG1012	belongs to the aldehyde dehydrogenase family
FIU86_RS21630	COG1902	pentaerythritol trinitrate reductase activity
FIU86_RS21635	COG0667	Aldo Keto reductase
FIU86_RS21650	COG2130	NADP-dependent
FIU86_RS21655	COG1979	alcohol dehydrogenase
FIU86_RS21660	COG1764	response to oxidative stress
FIU86_RS21665	COG1309	transcriptional regulator
FIU86_RS21670	COG0640	Transcriptional regulator
FIU86_RS21675	COG0477	Major facilitator Superfamily
FIU86_RS21690	COG3436	PFAM IS66 Orf2 family protein
FIU86_RS21710	COG3843	relaxase mobilization nuclease domain protein
FIU86_RS21725	COG3831	ATPase activity
FIU86_RS21735	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FIU86_RS21760	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
FIU86_RS21765	COG2948	multi-organism process
FIU86_RS21775	COG3736	Type IV secretory pathway, component VirB8
FIU86_RS21795	COG1196	nuclear chromosome segregation
FIU86_RS21795	COG0739	heme binding
FIU86_RS21795	COG0741	lytic transglycosylase activity
FIU86_RS21805	COG3451	type IV secretory pathway VirB4
FIU86_RS21820	COG1196	nuclear chromosome segregation
FIU86_RS21820	COG0741	lytic transglycosylase activity
FIU86_RS21820	COG0739	heme binding
FIU86_RS21845	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FIU86_RS21860	COG0167	dihydroorotate dehydrogenase activity
FIU86_RS21870	COG1802	Transcriptional regulator
FIU86_RS21875	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FIU86_RS21880	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FIU86_RS21915	COG1473	amidohydrolase
FIU86_RS21920	COG1475	DNA binding
FIU86_RS21990	COG1122	ATPase activity
FIU86_RS21995	COG1268	BioY protein
FIU86_RS22040	COG0739	heme binding
FIU86_RS22040	COG1196	nuclear chromosome segregation
FIU86_RS22040	COG0741	lytic transglycosylase activity
FIU86_RS22055	COG3451	type IV secretory pathway VirB4
FIU86_RS22065	COG0739	heme binding
FIU86_RS22065	COG1196	nuclear chromosome segregation
FIU86_RS22065	COG0741	lytic transglycosylase activity
FIU86_RS22085	COG2948	multi-organism process
FIU86_RS22090	COG4962	Type ii secretion system protein e
FIU86_RS22110	COG3505	Type IV secretory pathway VirD4
FIU86_RS22195	COG3742	Toxic component of a toxin-antitoxin (TA) module. An RNase
FIU86_RS22210	COG1525	nuclease
FIU86_RS22235	COG1475	DNA binding
FIU86_RS22280	COG1522	sequence-specific DNA binding
FIU86_RS22285	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FIU86_RS22370	COG0277	FAD linked oxidase domain protein
FIU86_RS22375	COG0583	DNA-binding transcription factor activity
FIU86_RS22385	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIU86_RS22395	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FIU86_RS22410	COG3547	Transposase (IS116 IS110 IS902 family)
FIU86_RS22430	COG3328	transposase activity
FIU86_RS22445	COG1192	Involved in chromosome partitioning