locus-tag	class	description
PG1C_RS00010	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
PG1C_RS00015	COG0594	ribonuclease P activity
PG1C_RS00020	COG0230	Belongs to the bacterial ribosomal protein bL34 family
PG1C_RS00025	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PG1C_RS00030	COG3385	transposase activity
PG1C_RS00035	COG0592	DNA-directed DNA polymerase activity
PG1C_RS00060	COG0708	Exodeoxyribonuclease III
PG1C_RS00065	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PG1C_RS00075	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PG1C_RS00080	COG0154	amidase activity
PG1C_RS00085	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PG1C_RS00090	COG1077	Cell shape determining protein MreB Mrl
PG1C_RS00095	COG1792	Involved in formation and maintenance of cell shape
PG1C_RS00105	COG0768	penicillin binding
PG1C_RS00110	COG0772	Belongs to the SEDS family
PG1C_RS00145	COG1686	Belongs to the peptidase S11 family
PG1C_RS00155	COG2921	Belongs to the UPF0250 family
PG1C_RS00160	COG0321	lipoyl(octanoyl) transferase activity
PG1C_RS00165	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PG1C_RS00170	COG0210	DNA helicase
PG1C_RS00175	COG3245	cytochrome
PG1C_RS00185	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
PG1C_RS00190	COG4633	Protein conserved in bacteria
PG1C_RS00195	COG0672	)-iron permease
PG1C_RS00210	COG0237	dephospho-CoA kinase activity
PG1C_RS00215	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
PG1C_RS00220	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
PG1C_RS00225	COG0494	nUDIX hydrolase
PG1C_RS00235	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
PG1C_RS00240	COG0004	ammonium transporteR
PG1C_RS00250	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PG1C_RS00260	COG1301	dicarboxylic acid transport
PG1C_RS00265	COG0625	glutathione transferase activity
PG1C_RS00270	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
PG1C_RS00280	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PG1C_RS00295	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PG1C_RS00305	COG0386	Belongs to the glutathione peroxidase family
PG1C_RS00335	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PG1C_RS00340	COG0459	protein refolding
PG1C_RS00350	COG3162	membrane
PG1C_RS00370	COG1396	sequence-specific DNA binding
PG1C_RS00375	COG2856	Zn peptidase
PG1C_RS00400	COG0789	Transcriptional regulator
PG1C_RS00515	COG1475	DNA binding
PG1C_RS00575	COG0616	signal peptide processing
PG1C_RS00765	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PG1C_RS00790	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
PG1C_RS00795	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PG1C_RS00800	COG2890	protein-(glutamine-N5) methyltransferase activity
PG1C_RS00810	COG0218	Necessary for normal cell division and for the maintenance of normal septation
PG1C_RS00825	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
PG1C_RS00835	COG1595	DNA-templated transcription, initiation
PG1C_RS00845	COG3220	belongs to the UPF0276 family
PG1C_RS00855	COG2259	Doxx family
PG1C_RS00880	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
PG1C_RS00895	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
PG1C_RS00905	COG4536	flavin adenine dinucleotide binding
PG1C_RS00915	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PG1C_RS00925	COG0741	lytic transglycosylase activity
PG1C_RS00930	COG0442	prolyl-tRNA aminoacylation
PG1C_RS00935	COG0494	nUDIX hydrolase
PG1C_RS00945	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
PG1C_RS00950	COG1765	OsmC-like protein
PG1C_RS00960	COG0438	transferase activity, transferring glycosyl groups
PG1C_RS00965	COG0859	PFAM glycosyl transferase family 9
PG1C_RS00990	COG1011	Hydrolase
PG1C_RS00995	COG1024	Enoyl-CoA hydratase
PG1C_RS01000	COG2814	Major facilitator Superfamily
PG1C_RS01005	COG1902	pentaerythritol trinitrate reductase activity
PG1C_RS01005	COG0446	pyridine nucleotide-disulphide oxidoreductase
PG1C_RS01015	COG1960	acyl-CoA dehydrogenase activity
PG1C_RS01020	COG1960	acyl-CoA dehydrogenase activity
PG1C_RS01025	COG1960	acyl-CoA dehydrogenase activity
PG1C_RS01035	COG0183	Belongs to the thiolase family
PG1C_RS01040	COG2030	dehydratase
PG1C_RS01045	COG1960	acyl-CoA dehydrogenase activity
PG1C_RS01055	COG1028	Short-chain dehydrogenase reductase Sdr
PG1C_RS01115	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
PG1C_RS01120	COG0385	Bile acid
PG1C_RS01145	COG0741	lytic transglycosylase activity
PG1C_RS01150	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PG1C_RS01170	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
PG1C_RS01175	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PG1C_RS01180	COG1238	metal cluster binding
PG1C_RS01190	COG2945	thiolester hydrolase activity
PG1C_RS01210	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PG1C_RS01225	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
PG1C_RS01230	COG1137	ATPase activity
PG1C_RS01235	COG2137	regulation of response to DNA damage stimulus
PG1C_RS01240	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PG1C_RS01245	COG1546	Belongs to the CinA family
PG1C_RS01250	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
PG1C_RS01260	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PG1C_RS01265	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
PG1C_RS01280	COG4232	protein-disulfide reductase activity
PG1C_RS01305	COG3385	transposase activity
PG1C_RS01315	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
PG1C_RS01320	COG0018	arginyl-trna synthetase
PG1C_RS01330	COG4221	oxidoreductase activity
PG1C_RS01335	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PG1C_RS01345	COG0651	ATP synthesis coupled electron transport
PG1C_RS01360	COG0651	ATP synthesis coupled electron transport
PG1C_RS01365	COG0649	NAD binding
PG1C_RS01365	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PG1C_RS01370	COG3260	NADH ubiquinone oxidoreductase 20
PG1C_RS01375	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
PG1C_RS01380	COG0189	ligase activity
PG1C_RS01380	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PG1C_RS01385	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PG1C_RS01385	COG0189	ligase activity
PG1C_RS01390	COG1132	(ABC) transporter
PG1C_RS01405	COG3243	poly(R)-hydroxyalkanoic acid synthase
PG1C_RS01415	COG1960	acyl-CoA dehydrogenase activity
PG1C_RS01425	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PG1C_RS01435	COG4770	biotin carboxylase activity
PG1C_RS01440	COG2814	Major facilitator Superfamily
PG1C_RS01455	COG1660	Displays ATPase and GTPase activities
PG1C_RS01470	COG1194	a g-specific adenine glycosylase
PG1C_RS01475	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PG1C_RS01490	COG0791	NLP P60 protein
PG1C_RS01500	COG3568	Endonuclease Exonuclease Phosphatase
PG1C_RS01510	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
PG1C_RS01525	COG0174	glutamine synthetase
PG1C_RS01535	COG3852	Histidine kinase
PG1C_RS01545	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
PG1C_RS01545	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
PG1C_RS01550	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
PG1C_RS01565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PG1C_RS01575	COG2264	protein methyltransferase activity
PG1C_RS01580	COG0439	Biotin carboxylase
PG1C_RS01585	COG0511	ligase activity, forming carbon-carbon bonds
PG1C_RS01590	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
PG1C_RS01595	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PG1C_RS01605	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PG1C_RS01615	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PG1C_RS01620	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
PG1C_RS01630	COG1845	cytochrome c oxidase, subunit III
PG1C_RS01655	COG1999	signal sequence binding
PG1C_RS01660	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PG1C_RS01665	COG2177	Part of the ABC transporter FtsEX involved in
PG1C_RS01670	COG2884	Cell division ATP-binding protein ftsE
PG1C_RS01695	COG0612	Peptidase, M16
PG1C_RS01700	COG0612	Peptidase, M16
PG1C_RS01705	COG0742	ribosomal rna small subunit methyltransferase
PG1C_RS01710	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PG1C_RS01715	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
PG1C_RS01720	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
PG1C_RS01735	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PG1C_RS01745	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PG1C_RS01750	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
PG1C_RS01755	COG0193	aminoacyl-tRNA hydrolase activity
PG1C_RS01760	COG0012	GTP binding
PG1C_RS01775	COG3409	Peptidoglycan-binding domain 1 protein
PG1C_RS01775	COG3267	Type II secretory pathway component ExeA
PG1C_RS01780	COG1450	Type ii and iii secretion system protein
PG1C_RS01810	COG2165	general secretion pathway protein
PG1C_RS01820	COG1459	type II secretion system
PG1C_RS01825	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PG1C_RS01830	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
PG1C_RS01835	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
PG1C_RS01845	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
PG1C_RS01855	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PG1C_RS01860	COG0588	phosphoglycerate mutase activity
PG1C_RS01865	COG4942	peptidase
PG1C_RS01870	COG0793	Belongs to the peptidase S41A family
PG1C_RS01885	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PG1C_RS01885	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PG1C_RS01890	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PG1C_RS01895	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PG1C_RS01905	COG0406	alpha-ribazole phosphatase activity
PG1C_RS01915	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
PG1C_RS01920	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
PG1C_RS01925	COG2226	methyltransferase
PG1C_RS01940	COG0586	Pfam SNARE associated Golgi protein
PG1C_RS01945	COG0642	Histidine kinase
PG1C_RS01965	COG1131	(ABC) transporter
PG1C_RS01995	COG0671	phosphoesterase, PA-phosphatase related
PG1C_RS02015	COG0312	modulator of DNA gyrase
PG1C_RS02020	COG3028	Belongs to the UPF0307 family
PG1C_RS02030	COG1960	acyl-CoA dehydrogenase activity
PG1C_RS02035	COG0183	Belongs to the thiolase family
PG1C_RS02045	COG2226	methyltransferase
PG1C_RS02055	COG5265	(ABC) transporter
PG1C_RS02070	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
PG1C_RS02075	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
PG1C_RS02080	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PG1C_RS02085	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PG1C_RS02105	COG0009	L-threonylcarbamoyladenylate synthase
PG1C_RS02115	COG0151	Belongs to the GarS family
PG1C_RS02130	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
PG1C_RS02135	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PG1C_RS02140	COG0798	PFAM Bile acid sodium symporter
PG1C_RS02155	COG0640	Transcriptional regulator
PG1C_RS02160	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PG1C_RS02165	COG0006	proline dipeptidase activity
PG1C_RS02180	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
PG1C_RS02185	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PG1C_RS02190	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
PG1C_RS02195	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
PG1C_RS02200	COG0708	Exodeoxyribonuclease III
PG1C_RS02215	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PG1C_RS02220	COG1230	cation diffusion facilitator family transporter
PG1C_RS02235	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
PG1C_RS02260	COG1752	Esterase of the alpha-beta hydrolase superfamily
PG1C_RS02275	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
PG1C_RS02280	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PG1C_RS02285	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PG1C_RS02290	COG1832	CoA-binding protein
PG1C_RS02305	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
PG1C_RS02310	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
PG1C_RS02315	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
PG1C_RS02320	COG2205	protein histidine kinase activity
PG1C_RS02325	COG0745	RESPONSE REGULATOR receiver
PG1C_RS02330	COG0602	queuosine metabolic process
PG1C_RS02345	COG0823	Involved in the tonB-independent uptake of proteins
PG1C_RS02365	COG1028	Short-chain dehydrogenase reductase Sdr
PG1C_RS02375	COG0824	Thioesterase
PG1C_RS02380	COG2255	four-way junction helicase activity
PG1C_RS02385	COG0632	four-way junction helicase activity
PG1C_RS02390	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
PG1C_RS02395	COG0217	transcriptional regulatory protein
PG1C_RS02415	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
PG1C_RS02425	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
PG1C_RS02440	COG4628	conserved protein (DUF2132)
PG1C_RS02450	COG2072	flavoprotein involved in K transport
PG1C_RS02460	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
PG1C_RS02470	COG0625	glutathione transferase activity
PG1C_RS02475	COG1028	Short-chain dehydrogenase reductase Sdr
PG1C_RS02495	COG1028	Short-chain dehydrogenase reductase Sdr
PG1C_RS02510	COG0280	phosphate acetyltransferase
PG1C_RS02510	COG0281	malic enzyme
PG1C_RS02515	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
PG1C_RS02535	COG0210	DNA helicase
PG1C_RS02565	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
PG1C_RS02570	COG0475	glutathione-regulated potassium exporter activity
PG1C_RS02600	COG0028	Belongs to the TPP enzyme family
PG1C_RS02605	COG2001	Belongs to the MraZ family
PG1C_RS02610	COG0275	rRNA processing
PG1C_RS02625	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PG1C_RS02630	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
PG1C_RS02635	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PG1C_RS02640	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PG1C_RS02645	COG0772	Belongs to the SEDS family
PG1C_RS02650	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PG1C_RS02660	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PG1C_RS02665	COG0812	UDP-N-acetylmuramate dehydrogenase activity
PG1C_RS02670	COG1181	Belongs to the D-alanine--D-alanine ligase family
PG1C_RS02675	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
PG1C_RS02690	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
PG1C_RS02705	COG0653	protein targeting
PG1C_RS02710	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
PG1C_RS02715	COG0235	Class ii aldolase
PG1C_RS02720	COG1715	Restriction endonuclease
PG1C_RS02725	COG1032	radical SAM domain protein
PG1C_RS02740	COG2816	NAD+ diphosphatase activity
PG1C_RS02755	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
PG1C_RS02765	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PG1C_RS02775	COG1573	uracil-dna glycosylase
PG1C_RS02780	COG0322	excinuclease ABC activity
PG1C_RS02785	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PG1C_RS02810	COG2948	multi-organism process
PG1C_RS02840	COG3451	type IV secretory pathway VirB4
PG1C_RS02855	COG4962	Type ii secretion system protein e
PG1C_RS02885	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PG1C_RS02930	COG1192	Involved in chromosome partitioning
PG1C_RS02970	COG5489	Protein of unknown function (DUF736)
PG1C_RS02985	COG2003	Belongs to the UPF0758 family
PG1C_RS03050	COG3385	transposase activity
PG1C_RS03060	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
PG1C_RS03085	COG0583	DNA-binding transcription factor activity
PG1C_RS03115	COG3657	addiction module killer protein
PG1C_RS03170	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PG1C_RS03175	COG0483	inositol monophosphate 1-phosphatase activity
PG1C_RS03190	COG1959	2 iron, 2 sulfur cluster binding
PG1C_RS03195	COG1104	cysteine desulfurase activity
PG1C_RS03200	COG1104	cysteine desulfurase activity
PG1C_RS03205	COG0822	iron-sulfur transferase activity
PG1C_RS03210	COG0316	Belongs to the HesB IscA family
PG1C_RS03215	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
PG1C_RS03220	COG0443	Heat shock 70 kDa protein
PG1C_RS03235	COG0084	hydrolase, TatD family'
PG1C_RS03240	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PG1C_RS03255	COG1960	acyl-CoA dehydrogenase activity
PG1C_RS03290	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PG1C_RS03295	COG1393	Belongs to the ArsC family
PG1C_RS03305	COG0577	efflux transmembrane transporter activity
PG1C_RS03305	COG1136	(ABC) transporter
PG1C_RS03310	COG0577	efflux transmembrane transporter activity
PG1C_RS03310	COG1136	(ABC) transporter
PG1C_RS03315	COG1136	(ABC) transporter
PG1C_RS03315	COG0577	efflux transmembrane transporter activity
PG1C_RS03320	COG1902	pentaerythritol trinitrate reductase activity
PG1C_RS03325	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
PG1C_RS03330	COG0628	permease
PG1C_RS03335	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PG1C_RS03345	COG0488	(ABC) transporter
PG1C_RS03350	COG4133	protoheme IX ABC transporter activity
PG1C_RS03355	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PG1C_RS03370	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
PG1C_RS03380	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PG1C_RS03415	COG2022	thiamine diphosphate biosynthetic process
PG1C_RS03425	COG0220	tRNA (guanine-N7-)-methyltransferase activity
PG1C_RS03440	COG0598	Magnesium transport protein CorA
PG1C_RS03445	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PG1C_RS03450	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PG1C_RS03460	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
PG1C_RS03465	COG2815	serine threonine protein kinase
PG1C_RS03465	COG0515	serine threonine protein kinase
PG1C_RS03470	COG1561	YicC-like family, N-terminal region
PG1C_RS03475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PG1C_RS03485	COG3706	GGDEF domain
PG1C_RS03505	COG0194	GDP metabolic process
PG1C_RS03510	COG1758	RNA polymerase activity
PG1C_RS03515	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PG1C_RS03540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PG1C_RS03550	COG5002	protein histidine kinase activity
PG1C_RS03555	COG0745	RESPONSE REGULATOR receiver
PG1C_RS03565	COG0745	RESPONSE REGULATOR receiver
PG1C_RS03570	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
PG1C_RS03575	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PG1C_RS03640	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
PG1C_RS03645	COG2951	lytic endotransglycosylase activity
PG1C_RS03660	COG0714	Associated with various cellular activities
PG1C_RS03675	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
PG1C_RS03690	COG2850	peptidyl-arginine hydroxylation
PG1C_RS03695	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PG1C_RS03700	COG3385	transposase activity
PG1C_RS03710	COG1012	belongs to the aldehyde dehydrogenase family
PG1C_RS03725	COG0473	3-isopropylmalate dehydrogenase activity
PG1C_RS03730	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
PG1C_RS03735	COG0596	Alpha beta hydrolase
PG1C_RS03755	COG0720	synthase
PG1C_RS03770	COG0248	Ppx GppA phosphatase
PG1C_RS03775	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
PG1C_RS03780	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PG1C_RS03785	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PG1C_RS03785	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PG1C_RS03795	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PG1C_RS03805	COG0557	exoribonuclease II activity
PG1C_RS03820	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PG1C_RS03825	COG0795	lipopolysaccharide-transporting ATPase activity
PG1C_RS03855	COG0028	Belongs to the TPP enzyme family
PG1C_RS03860	COG0440	acetolactate synthase activity
PG1C_RS03865	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PG1C_RS03870	COG0688	phosphatidylethanolamine metabolic process
PG1C_RS03875	COG1183	phosphatidylcholine synthase activity
PG1C_RS03880	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PG1C_RS03895	COG1295	ribonuclease BN
PG1C_RS03900	COG0284	orotidine-5'-phosphate decarboxylase activity
PG1C_RS03905	COG0228	four-way junction DNA binding
PG1C_RS03910	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PG1C_RS03915	COG0336	Belongs to the RNA methyltransferase TrmD family
PG1C_RS03920	COG0335	large ribosomal subunit rRNA binding
PG1C_RS03925	COG1469	GTP cyclohydrolase I activity
PG1C_RS03930	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PG1C_RS03935	COG0142	geranyltranstransferase activity
PG1C_RS03940	COG1722	exodeoxyribonuclease VII activity
PG1C_RS03955	COG0267	Belongs to the bacterial ribosomal protein bL33 family
PG1C_RS03960	COG0227	Belongs to the bacterial ribosomal protein bL28 family
PG1C_RS03965	COG2003	Belongs to the UPF0758 family
PG1C_RS03970	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PG1C_RS03975	COG0756	dUTP diphosphatase activity
PG1C_RS03980	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
PG1C_RS03990	COG0542	response to heat
PG1C_RS03995	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
PG1C_RS04000	COG1278	Cold shock
PG1C_RS04005	COG0538	isocitrate dehydrogenase activity
PG1C_RS04010	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PG1C_RS04015	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
PG1C_RS04020	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PG1C_RS04025	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
PG1C_RS04030	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PG1C_RS04040	COG0316	Belongs to the HesB IscA family
PG1C_RS04045	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
PG1C_RS04055	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PG1C_RS04095	COG3328	transposase activity
PG1C_RS04105	COG2967	ApaG domain
PG1C_RS04110	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
PG1C_RS04115	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PG1C_RS04120	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
PG1C_RS04125	COG0515	serine threonine protein kinase
PG1C_RS04125	COG2815	serine threonine protein kinase
PG1C_RS04130	COG0165	Argininosuccinate lyase
PG1C_RS04145	COG0142	geranyltranstransferase activity
PG1C_RS04185	COG0556	nucleotide-excision repair
PG1C_RS04225	COG0210	DNA helicase
PG1C_RS04240	COG0039	L-malate dehydrogenase activity
PG1C_RS04260	COG1053	succinate dehydrogenase
PG1C_RS04265	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
PG1C_RS04270	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
PG1C_RS04275	COG0372	Belongs to the citrate synthase family
PG1C_RS04280	COG0567	Dehydrogenase, E1 component
PG1C_RS04285	COG0508	dehydrogenase complex catalyzes the overall conversion of
PG1C_RS04290	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PG1C_RS04295	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
PG1C_RS04300	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PG1C_RS04305	COG1047	Peptidyl-prolyl cis-trans
PG1C_RS04320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PG1C_RS04330	COG3038	cytochrome b561
PG1C_RS04335	COG1846	Transcriptional regulator
PG1C_RS04340	COG3385	transposase activity
PG1C_RS04405	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PG1C_RS04425	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
PG1C_RS04440	COG4638	Rieske (2fe-2S)
PG1C_RS04450	COG1063	alcohol dehydrogenase
PG1C_RS04490	COG4638	Rieske (2fe-2S)
PG1C_RS04540	COG4772	TonB-dependent receptor
PG1C_RS04570	COG2197	response regulator
PG1C_RS04590	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PG1C_RS04595	COG1196	nuclear chromosome segregation
PG1C_RS04605	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PG1C_RS04610	COG1210	Utp--glucose-1-phosphate uridylyltransferase
PG1C_RS04615	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
PG1C_RS04640	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PG1C_RS04645	COG3174	membrane
PG1C_RS04650	COG1028	Short-chain dehydrogenase reductase Sdr
PG1C_RS04655	COG4638	Rieske (2fe-2S)
PG1C_RS04675	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
PG1C_RS04680	COG4638	Rieske (2fe-2S)
PG1C_RS04685	COG4638	Rieske (2fe-2S)
PG1C_RS04710	COG0251	oxidation-reduction process
PG1C_RS04740	COG0640	Transcriptional regulator
PG1C_RS04755	COG0730	response to heat
PG1C_RS04760	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
PG1C_RS04765	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
PG1C_RS04775	COG2346	COG2346, Truncated hemoglobins
PG1C_RS04795	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
PG1C_RS04800	COG2867	negative regulation of translational initiation
PG1C_RS04805	COG2914	Belongs to the UPF0125 (RnfH) family
PG1C_RS04815	COG0518	GMP synthase (glutamine-hydrolyzing) activity
PG1C_RS04815	COG0519	Catalyzes the synthesis of GMP from XMP
PG1C_RS04820	COG0582	viral genome integration into host DNA
PG1C_RS04835	COG0210	DNA helicase
PG1C_RS04845	COG0629	single-stranded DNA binding
PG1C_RS04865	COG3723	Recombinational DNA repair protein, rece pathway
PG1C_RS04880	COG1475	DNA binding
PG1C_RS04955	COG2003	Belongs to the UPF0758 family
PG1C_RS05000	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PG1C_RS05055	COG1074	ATP-dependent DNA helicase activity
PG1C_RS05070	COG1121	(ABC) transporter
PG1C_RS05075	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
PG1C_RS05085	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PG1C_RS05115	COG0210	DNA helicase
PG1C_RS05260	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PG1C_RS05350	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PG1C_RS05365	COG3177	Filamentation induced by cAMP protein fic
PG1C_RS05380	COG1396	sequence-specific DNA binding
PG1C_RS05390	COG4774	siderophore transport
PG1C_RS05410	COG0261	This protein binds to 23S rRNA in the presence of protein L20
PG1C_RS05415	COG0211	Belongs to the bacterial ribosomal protein bL27 family
PG1C_RS05420	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PG1C_RS05425	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PG1C_RS05450	COG4983	Phage plasmid primase, P4 family domain protein
PG1C_RS05480	COG0582	viral genome integration into host DNA
PG1C_RS05485	COG1530	ribonuclease E activity
PG1C_RS05490	COG0564	pseudouridine synthase activity
PG1C_RS05495	COG0546	phosphoglycolate phosphatase activity
PG1C_RS05500	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
PG1C_RS05510	COG0254	rRNA binding
PG1C_RS05515	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PG1C_RS05530	COG0517	IMP dehydrogenase activity
PG1C_RS05530	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
PG1C_RS05530	COG0617	tRNA 3'-terminal CCA addition
PG1C_RS05535	COG0318	PFAM AMP-dependent synthetase and ligase
PG1C_RS05540	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PG1C_RS05545	COG2814	Major facilitator Superfamily
PG1C_RS05550	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PG1C_RS05560	COG0066	3-isopropylmalate dehydratase activity
PG1C_RS05565	COG0473	3-isopropylmalate dehydrogenase activity
PG1C_RS05585	COG0101	tRNA pseudouridine synthase activity
PG1C_RS05590	COG0135	phosphoribosylanthranilate isomerase activity
PG1C_RS05595	COG0133	tryptophan synthase activity
PG1C_RS05600	COG0159	tryptophan synthase activity
PG1C_RS05605	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PG1C_RS05610	COG0285	dihydrofolate synthase activity
PG1C_RS05635	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PG1C_RS05640	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PG1C_RS05645	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PG1C_RS05655	COG0215	cysteine-tRNA ligase activity
PG1C_RS05750	COG0028	Belongs to the TPP enzyme family
PG1C_RS05755	COG0484	heat shock protein binding
PG1C_RS05760	COG0443	Heat shock 70 kDa protein
PG1C_RS05765	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PG1C_RS05770	COG4638	Rieske (2fe-2S)
PG1C_RS05780	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
PG1C_RS05785	COG1187	pseudouridine synthase activity
PG1C_RS05790	COG2076	Multidrug Resistance protein
PG1C_RS05810	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
PG1C_RS05815	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PG1C_RS05820	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
PG1C_RS05825	COG3328	transposase activity
PG1C_RS05870	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PG1C_RS05875	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PG1C_RS05880	COG1643	Atp-dependent helicase
PG1C_RS05890	COG1546	Belongs to the CinA family
PG1C_RS05890	COG1058	Belongs to the CinA family
PG1C_RS05905	COG0312	modulator of DNA gyrase
PG1C_RS05910	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PG1C_RS05915	COG3164	Protein of unknown function
PG1C_RS05920	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
PG1C_RS05925	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PG1C_RS05935	COG2084	Dehydrogenase
PG1C_RS05955	COG1024	Enoyl-CoA hydratase
PG1C_RS05970	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
PG1C_RS05990	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PG1C_RS05990	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PG1C_RS05995	COG0489	protein tyrosine kinase activity
PG1C_RS06015	COG1376	ErfK ybiS ycfS ynhG family protein
PG1C_RS06020	COG3108	Peptidase M15
PG1C_RS06025	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
PG1C_RS06030	COG0717	Belongs to the dCTP deaminase family
PG1C_RS06045	COG0297	glycogen (starch) synthase activity
PG1C_RS06060	COG0842	Transport permease protein
PG1C_RS06060	COG1129	ABC transporter
PG1C_RS06065	COG0166	Belongs to the GPI family
PG1C_RS06075	COG1449	Belongs to the glycosyl hydrolase 57 family
PG1C_RS06085	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PG1C_RS06090	COG1830	Aldolase
PG1C_RS06105	COG2095	MarC family integral membrane protein
PG1C_RS06110	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PG1C_RS06115	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PG1C_RS06125	COG0837	glucose binding
PG1C_RS06130	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PG1C_RS06135	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PG1C_RS06140	COG3706	GGDEF domain
PG1C_RS06150	COG0521	Mo-molybdopterin cofactor biosynthetic process
PG1C_RS06165	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PG1C_RS06170	COG2814	Major facilitator Superfamily
PG1C_RS06175	COG2070	2-Nitropropane dioxygenase
PG1C_RS06200	COG1538	Outer membrane efflux protein
PG1C_RS06205	COG1566	PFAM secretion protein HlyD family protein
PG1C_RS06210	COG0589	response to stress
PG1C_RS06215	COG0679	Auxin Efflux Carrier
PG1C_RS06235	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
PG1C_RS06245	COG1686	Belongs to the peptidase S11 family
PG1C_RS06250	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PG1C_RS06255	COG0181	hydroxymethylbilane synthase activity
PG1C_RS06260	COG1587	Uroporphyrinogen-III synthase
PG1C_RS06265	COG2959	enzyme of heme biosynthesis
PG1C_RS06275	COG0408	coproporphyrinogen oxidase activity
PG1C_RS06280	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PG1C_RS06285	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PG1C_RS06290	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
PG1C_RS06290	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PG1C_RS06300	COG0069	glutamate synthase activity
PG1C_RS06335	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
PG1C_RS06340	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PG1C_RS06350	COG3328	transposase activity
PG1C_RS06360	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
PG1C_RS06390	COG0709	Synthesizes selenophosphate from selenide and ATP
PG1C_RS06395	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
PG1C_RS06405	COG2030	dehydratase
PG1C_RS06415	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PG1C_RS06425	COG2217	Heavy metal translocating P-type atpase
PG1C_RS06435	COG3278	Belongs to the heme-copper respiratory oxidase family
PG1C_RS06470	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PG1C_RS06475	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PG1C_RS06515	COG0346	lactoylglutathione lyase activity
PG1C_RS06575	COG4638	Rieske (2fe-2S)
PG1C_RS06580	COG4638	Rieske (2fe-2S)
PG1C_RS06615	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PG1C_RS06620	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
PG1C_RS06635	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
PG1C_RS06655	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PG1C_RS06665	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
PG1C_RS06670	COG1322	Protein conserved in bacteria
PG1C_RS06680	COG1074	ATP-dependent DNA helicase activity
PG1C_RS06705	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
PG1C_RS06715	COG0052	Belongs to the universal ribosomal protein uS2 family
PG1C_RS06720	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PG1C_RS06725	COG0528	UMP kinase activity
PG1C_RS06730	COG0233	cytoplasmic translational termination
PG1C_RS06735	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PG1C_RS06745	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
PG1C_RS06755	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PG1C_RS06765	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PG1C_RS06770	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PG1C_RS06775	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PG1C_RS06780	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PG1C_RS06785	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PG1C_RS06790	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PG1C_RS06800	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
PG1C_RS06815	COG0330	HflC and HflK could
PG1C_RS06830	COG1573	uracil-dna glycosylase
PG1C_RS06835	COG2205	protein histidine kinase activity
PG1C_RS06845	COG2204	response regulator
PG1C_RS06885	COG0477	Major facilitator Superfamily
PG1C_RS06890	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PG1C_RS06925	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
PG1C_RS06930	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PG1C_RS06935	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PG1C_RS06940	COG0291	Belongs to the bacterial ribosomal protein bL35 family
PG1C_RS06945	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PG1C_RS06950	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PG1C_RS06955	COG0072	phenylalanine-tRNA ligase activity
PG1C_RS06955	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PG1C_RS06960	COG0776	regulation of translation
PG1C_RS07085	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
PG1C_RS07105	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PG1C_RS07110	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PG1C_RS07115	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PG1C_RS07120	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PG1C_RS07125	COG0723	plastoquinol--plastocyanin reductase activity
PG1C_RS07130	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
PG1C_RS07135	COG2857	Cytochrome c1
PG1C_RS07140	COG0625	glutathione transferase activity
PG1C_RS07145	COG2969	positive regulation of protein catabolic process
PG1C_RS07150	COG0582	viral genome integration into host DNA
PG1C_RS07190	COG0488	(ABC) transporter
PG1C_RS07200	COG2827	Endonuclease containing a URI domain
PG1C_RS07205	COG1301	dicarboxylic acid transport
PG1C_RS07215	COG0346	lactoylglutathione lyase activity
PG1C_RS07235	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
PG1C_RS07245	COG0751	glycine-tRNA ligase activity
PG1C_RS07250	COG0752	glycyl-tRNA synthetase alpha subunit
PG1C_RS07260	COG2199	diguanylate cyclase activity
PG1C_RS07260	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
PG1C_RS07290	COG0815	Transfers the fatty acyl group on membrane lipoproteins
PG1C_RS07295	COG4535	Mg2 and Co2 transporter CorC
PG1C_RS07300	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PG1C_RS07305	COG1702	phosphate starvation-inducible protein PhoH
PG1C_RS07315	COG0601	transmembrane transport
PG1C_RS07320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PG1C_RS07330	COG0741	lytic transglycosylase activity
PG1C_RS07330	COG1388	LysM domain
PG1C_RS07335	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PG1C_RS07340	COG2226	methyltransferase
PG1C_RS07345	COG0328	RNA-DNA hybrid ribonuclease activity
PG1C_RS07360	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
PG1C_RS07370	COG0564	pseudouridine synthase activity
PG1C_RS07380	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PG1C_RS07385	COG1511	domain protein
PG1C_RS07385	COG3264	Mechanosensitive ion channel
PG1C_RS07390	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PG1C_RS07395	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PG1C_RS07395	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PG1C_RS07405	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PG1C_RS07415	COG0586	Pfam SNARE associated Golgi protein
PG1C_RS07420	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PG1C_RS07425	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PG1C_RS07430	COG0302	gtp cyclohydrolase
PG1C_RS07455	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PG1C_RS07495	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PG1C_RS07505	COG0671	phosphoesterase, PA-phosphatase related
PG1C_RS07510	COG0542	response to heat
PG1C_RS07520	COG2818	Glycosylase
PG1C_RS07525	COG0527	aspartate kinase activity
PG1C_RS07545	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PG1C_RS07555	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
PG1C_RS07555	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PG1C_RS07560	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
PG1C_RS07580	COG0504	CTP synthase activity
PG1C_RS07585	COG2877	3-deoxy-8-phosphooctulonate synthase activity
PG1C_RS07590	COG0148	phosphopyruvate hydratase activity
PG1C_RS07595	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
PG1C_RS07615	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
PG1C_RS07620	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
PG1C_RS07625	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
PG1C_RS07640	COG0488	(ABC) transporter
PG1C_RS07670	COG0826	peptidase U32
PG1C_RS07680	COG2153	protein acetylation
PG1C_RS07685	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
PG1C_RS07700	COG0084	hydrolase, TatD family'
PG1C_RS07710	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PG1C_RS07715	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PG1C_RS07735	COG0427	acetyl-CoA hydrolase
PG1C_RS07740	COG1472	Belongs to the glycosyl hydrolase 3 family
PG1C_RS07745	COG0736	holo-[acyl-carrier-protein] synthase activity
PG1C_RS07750	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
PG1C_RS07755	COG1381	Involved in DNA repair and RecF pathway recombination
PG1C_RS07760	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PG1C_RS07765	COG0571	ribonuclease III activity
PG1C_RS07775	COG0681	Belongs to the peptidase S26 family
PG1C_RS07780	COG0481	GTPase activity
PG1C_RS07790	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PG1C_RS07815	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
PG1C_RS07825	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PG1C_RS07830	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PG1C_RS07840	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
PG1C_RS07845	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PG1C_RS07850	COG0416	fatty acid biosynthetic process
PG1C_RS07855	COG0333	Belongs to the bacterial ribosomal protein bL32 family
PG1C_RS07860	COG1399	metal-binding, possibly nucleic acid-binding protein
PG1C_RS07865	COG0424	maF-like protein
PG1C_RS07880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PG1C_RS07885	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PG1C_RS07890	COG2917	probably involved in intracellular septation
PG1C_RS07895	COG2350	Protein conserved in bacteria
PG1C_RS07900	COG0271	Belongs to the BolA IbaG family
PG1C_RS07905	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PG1C_RS07920	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PG1C_RS07920	COG0047	phosphoribosylformylglycinamidine synthase activity
PG1C_RS07925	COG3328	transposase activity
PG1C_RS07985	COG1136	(ABC) transporter
PG1C_RS07995	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
PG1C_RS08000	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
PG1C_RS08020	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PG1C_RS08030	COG1944	ATP diphosphatase activity
PG1C_RS08050	COG2189	Belongs to the N(4) N(6)-methyltransferase family
PG1C_RS08060	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PG1C_RS08065	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
PG1C_RS08075	COG1012	belongs to the aldehyde dehydrogenase family
PG1C_RS08085	COG0314	molybdopterin synthase activity
PG1C_RS08090	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
PG1C_RS08100	COG1763	Mo-molybdopterin cofactor biosynthetic process
PG1C_RS08110	COG1199	ATP-dependent helicase activity
PG1C_RS08120	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
PG1C_RS08140	COG0753	catalase activity
PG1C_RS08170	COG1960	acyl-CoA dehydrogenase activity
PG1C_RS08185	COG4206	TonB-dependent receptor
PG1C_RS08190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PG1C_RS08195	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
PG1C_RS08220	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
PG1C_RS08250	COG3411	Ferredoxin
PG1C_RS08260	COG1797	cobyrinic acid a,c-diamide synthase activity
PG1C_RS08265	COG0778	Nitroreductase
PG1C_RS08285	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PG1C_RS08290	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PG1C_RS08295	COG0697	spore germination
PG1C_RS08300	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PG1C_RS08310	COG1271	oxidase subunit
PG1C_RS08315	COG1294	oxidase, subunit
PG1C_RS08325	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
PG1C_RS08330	COG1492	cobalamin metabolic process
PG1C_RS08345	COG1902	pentaerythritol trinitrate reductase activity
PG1C_RS08350	COG0500	methyltransferase
PG1C_RS08355	COG0667	Aldo Keto reductase
PG1C_RS08360	COG0667	Aldo Keto reductase
PG1C_RS08365	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
PG1C_RS08370	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
PG1C_RS08380	COG0494	nUDIX hydrolase
PG1C_RS08385	COG1007	ATP synthesis coupled electron transport
PG1C_RS08400	COG0713	ATP synthesis coupled electron transport
PG1C_RS08410	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PG1C_RS08415	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
PG1C_RS08425	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
PG1C_RS08435	COG0649	NAD binding
PG1C_RS08440	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PG1C_RS08445	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PG1C_RS08450	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PG1C_RS08465	COG0149	triose-phosphate isomerase activity
PG1C_RS08470	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
PG1C_RS08475	COG0581	inorganic phosphate transmembrane transporter activity
PG1C_RS08480	COG0573	inorganic phosphate transmembrane transporter activity
PG1C_RS08485	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
PG1C_RS08495	COG0438	transferase activity, transferring glycosyl groups
PG1C_RS08505	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PG1C_RS08505	COG0438	transferase activity, transferring glycosyl groups
PG1C_RS08510	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PG1C_RS08515	COG2199	diguanylate cyclase activity
PG1C_RS08515	COG2200	EAL domain
PG1C_RS08520	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PG1C_RS08530	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PG1C_RS08535	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
PG1C_RS08550	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PG1C_RS08555	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
PG1C_RS08560	COG0505	Belongs to the CarA family
PG1C_RS08580	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
PG1C_RS08585	COG0205	6-phosphofructokinase activity
PG1C_RS08590	COG0563	adenylate kinase activity
PG1C_RS08595	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
PG1C_RS08600	COG2835	tetraacyldisaccharide 4'-kinase activity
PG1C_RS08605	COG1663	tetraacyldisaccharide 4'-kinase activity
PG1C_RS08610	COG0848	biopolymer transport protein
PG1C_RS08615	COG0811	peptide transport
PG1C_RS08625	COG1570	exodeoxyribonuclease VII activity
PG1C_RS08630	COG0268	Binds directly to 16S ribosomal RNA
PG1C_RS08650	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
PG1C_RS08655	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PG1C_RS08665	COG2119	membrane
PG1C_RS08670	COG0582	viral genome integration into host DNA
PG1C_RS08680	COG0582	viral genome integration into host DNA
PG1C_RS08690	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PG1C_RS08695	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PG1C_RS08700	COG0740	serine-type endopeptidase activity
PG1C_RS08705	COG0544	peptidyl-prolyl cis-trans isomerase activity
PG1C_RS08715	COG1562	ergosterol biosynthetic process
PG1C_RS08725	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
PG1C_RS08730	COG4181	ATPase activity
PG1C_RS08750	COG3384	dioxygenase
PG1C_RS08770	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
PG1C_RS08775	COG0156	8-amino-7-oxononanoate synthase activity
PG1C_RS08785	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PG1C_RS08795	COG0583	DNA-binding transcription factor activity
PG1C_RS08805	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
PG1C_RS08815	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PG1C_RS08820	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
PG1C_RS08825	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
PG1C_RS08835	COG0776	regulation of translation
PG1C_RS08845	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
PG1C_RS08850	COG0287	Prephenate dehydrogenase
PG1C_RS08855	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PG1C_RS08865	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PG1C_RS08870	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PG1C_RS08880	COG0402	S-adenosylhomocysteine deaminase activity
PG1C_RS08890	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PG1C_RS08905	COG0789	Transcriptional regulator
PG1C_RS08935	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PG1C_RS08940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PG1C_RS08940	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PG1C_RS08945	COG2814	Major facilitator Superfamily
PG1C_RS08960	COG0640	Transcriptional regulator
PG1C_RS09010	COG0583	DNA-binding transcription factor activity
PG1C_RS09025	COG3550	peptidyl-serine autophosphorylation
PG1C_RS09045	COG3609	addiction module antidote protein, CC2985 family
PG1C_RS09105	COG0463	Glycosyl transferase, family 2
PG1C_RS09120	COG3958	Transketolase
PG1C_RS09125	COG3959	Transketolase, thiamine diphosphate binding domain
PG1C_RS09145	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
PG1C_RS09170	COG3385	transposase activity
PG1C_RS09190	COG0529	Catalyzes the synthesis of activated sulfate
PG1C_RS09225	COG0529	Catalyzes the synthesis of activated sulfate
PG1C_RS09275	COG1088	dTDP-glucose 4,6-dehydratase activity
PG1C_RS09285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PG1C_RS09290	COG0577	efflux transmembrane transporter activity
PG1C_RS09290	COG1136	(ABC) transporter
PG1C_RS09295	COG0577	efflux transmembrane transporter activity
PG1C_RS09295	COG1136	(ABC) transporter
PG1C_RS09310	COG0179	Fumarylacetoacetate (FAA) hydrolase
PG1C_RS09370	COG3077	Addiction module antitoxin, RelB DinJ family
PG1C_RS09385	COG0776	regulation of translation
PG1C_RS09405	COG5489	Protein of unknown function (DUF736)
PG1C_RS09415	COG1475	DNA binding
PG1C_RS09425	COG2003	Belongs to the UPF0758 family
PG1C_RS09440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PG1C_RS09445	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PG1C_RS09465	COG0347	Belongs to the P(II) protein family
PG1C_RS09475	COG1285	pathogenesis
PG1C_RS09535	COG1742	UPF0060 membrane protein
PG1C_RS09545	COG0789	Transcriptional regulator
PG1C_RS09555	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PG1C_RS09560	COG1196	nuclear chromosome segregation
PG1C_RS09585	COG3451	type IV secretory pathway VirB4
PG1C_RS09605	COG3736	Type IV secretory pathway, component VirB8
PG1C_RS09610	COG3504	Conjugal transfer protein
PG1C_RS09620	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
PG1C_RS09630	COG1674	ftsk spoiiie
PG1C_RS09655	COG3328	transposase activity
PG1C_RS09685	COG3328	transposase activity
PG1C_RS09690	COG0791	NLP P60 protein
PG1C_RS09700	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
PG1C_RS09705	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
PG1C_RS09720	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PG1C_RS09725	COG0497	DNA recombination
PG1C_RS09735	COG0735	belongs to the Fur family
PG1C_RS09740	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PG1C_RS09745	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
PG1C_RS09760	COG0242	peptide deformylase activity
PG1C_RS09770	COG2890	protein-(glutamine-N5) methyltransferase activity
PG1C_RS09775	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PG1C_RS09785	COG2171	N-acyltransferase activity
PG1C_RS09815	COG0277	FAD linked oxidase domain protein
PG1C_RS09820	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PG1C_RS09825	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
PG1C_RS09835	COG1028	Short-chain dehydrogenase reductase Sdr
PG1C_RS09840	COG3243	poly(R)-hydroxyalkanoic acid synthase
PG1C_RS09845	COG0428	transporter
PG1C_RS09855	COG2154	pterin-4-alpha-carbinolamine dehydratase
PG1C_RS09860	COG0501	Belongs to the peptidase M48B family
PG1C_RS09865	COG3328	transposase activity
PG1C_RS09890	COG4774	siderophore transport
PG1C_RS09895	COG3128	pkhd-type hydroxylase
PG1C_RS09905	COG0728	peptidoglycan biosynthetic process
PG1C_RS09920	COG3047	cAMP biosynthetic process
PG1C_RS09930	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
PG1C_RS09940	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PG1C_RS09955	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PG1C_RS09960	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
PG1C_RS09965	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
PG1C_RS10005	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PG1C_RS10005	COG1648	precorrin-2 dehydrogenase activity
PG1C_RS10025	COG0667	Aldo Keto reductase
PG1C_RS10035	COG0861	Integral membrane protein TerC family
PG1C_RS10045	COG0501	Belongs to the peptidase M48B family
PG1C_RS10065	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PG1C_RS10070	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PG1C_RS10080	COG0583	DNA-binding transcription factor activity
PG1C_RS10085	COG0513	Belongs to the DEAD box helicase family
PG1C_RS10095	COG2205	protein histidine kinase activity
PG1C_RS10095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PG1C_RS10110	COG0672	)-iron permease
PG1C_RS10125	COG0789	Transcriptional regulator
PG1C_RS10130	COG4943	cyclic-guanylate-specific phosphodiesterase activity
PG1C_RS10135	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
PG1C_RS10140	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
PG1C_RS10145	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
PG1C_RS10155	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PG1C_RS10160	COG0617	tRNA 3'-terminal CCA addition
PG1C_RS10165	COG0525	valine-tRNA ligase activity
PG1C_RS10170	COG0425	Belongs to the sulfur carrier protein TusA family
PG1C_RS10185	COG0463	Glycosyl transferase, family 2
PG1C_RS10190	COG1215	transferase activity, transferring glycosyl groups
PG1C_RS10210	COG1131	(ABC) transporter
PG1C_RS10230	COG4969	Belongs to the N-Me-Phe pilin family
PG1C_RS10235	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
PG1C_RS10240	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PG1C_RS10250	COG1716	ATPase activity
PG1C_RS10255	COG0631	protein serine/threonine phosphatase activity
PG1C_RS10260	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
PG1C_RS10265	COG0045	succinate-CoA ligase (ADP-forming) activity
PG1C_RS10275	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PG1C_RS10295	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PG1C_RS10305	COG0805	protein transport
PG1C_RS10310	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PG1C_RS10315	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PG1C_RS10325	COG0140	phosphoribosyl-ATP diphosphatase activity
PG1C_RS10330	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PG1C_RS10335	COG0107	imidazoleglycerol-phosphate synthase activity
PG1C_RS10340	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PG1C_RS10345	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PG1C_RS10350	COG0131	Imidazoleglycerol-phosphate dehydratase
PG1C_RS10355	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PG1C_RS10385	COG2132	Multicopper oxidase
PG1C_RS10400	COG2076	Multidrug Resistance protein
PG1C_RS10405	COG1216	Glycosyl transferase, family 2
PG1C_RS10410	COG0535	radical SAM domain protein
PG1C_RS10425	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PG1C_RS10440	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PG1C_RS10445	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
PG1C_RS10450	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PG1C_RS10460	COG0842	Transport permease protein
PG1C_RS10465	COG1131	(ABC) transporter
PG1C_RS10480	COG2853	Lipoprotein
PG1C_RS10485	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
PG1C_RS10490	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PG1C_RS10495	COG1127	ABC transporter
PG1C_RS10505	COG3267	Type II secretory pathway component ExeA
PG1C_RS10505	COG3409	Peptidoglycan-binding domain 1 protein
PG1C_RS10525	COG1459	type II secretion system
PG1C_RS10555	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
PG1C_RS10560	COG0546	phosphoglycolate phosphatase activity
PG1C_RS10625	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
PG1C_RS10635	COG2827	Endonuclease containing a URI domain
PG1C_RS10655	COG3177	Filamentation induced by cAMP protein fic
PG1C_RS10670	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PG1C_RS10675	COG0134	indole-3-glycerol-phosphate synthase activity
PG1C_RS10690	COG0861	Integral membrane protein TerC family
PG1C_RS10710	COG0418	dihydroorotase activity
PG1C_RS10715	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PG1C_RS10720	COG0792	nuclease activity
PG1C_RS10730	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
PG1C_RS10735	COG2823	Periplasmic or secreted lipoprotein
PG1C_RS10740	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
PG1C_RS10755	COG3384	dioxygenase
PG1C_RS10760	COG0583	DNA-binding transcription factor activity
PG1C_RS10775	COG0629	single-stranded DNA binding
PG1C_RS10780	COG2814	Major facilitator Superfamily
PG1C_RS10790	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PG1C_RS10795	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PG1C_RS10800	COG0137	argininosuccinate synthase activity
PG1C_RS10810	COG3123	guanosine phosphorylase activity
PG1C_RS10815	COG1666	GTP binding
PG1C_RS10820	COG0505	Belongs to the CarA family
PG1C_RS10830	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
PG1C_RS10835	COG0183	Belongs to the thiolase family
PG1C_RS10845	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
PG1C_RS10850	COG3383	formate dehydrogenase (NAD+) activity
PG1C_RS10870	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
PG1C_RS10895	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PG1C_RS10895	COG2813	Specifically methylates the guanine in position
PG1C_RS10900	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PG1C_RS10905	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PG1C_RS10910	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
PG1C_RS10925	COG0189	ligase activity
PG1C_RS10950	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PG1C_RS10950	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PG1C_RS10985	COG0438	transferase activity, transferring glycosyl groups
PG1C_RS11015	COG3290	protein histidine kinase activity
PG1C_RS11020	COG2204	response regulator
PG1C_RS11030	COG0739	heme binding
PG1C_RS11030	COG0741	lytic transglycosylase activity
PG1C_RS11030	COG1196	nuclear chromosome segregation
PG1C_RS11035	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PG1C_RS11060	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
PG1C_RS11065	COG4591	ABC-type transport system involved in lipoprotein release permease component
PG1C_RS11105	COG1136	(ABC) transporter
PG1C_RS11105	COG0577	efflux transmembrane transporter activity
PG1C_RS11115	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
PG1C_RS11170	COG0318	PFAM AMP-dependent synthetase and ligase
PG1C_RS11180	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PG1C_RS11190	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PG1C_RS11225	COG2852	Protein conserved in bacteria
PG1C_RS11235	COG0463	Glycosyl transferase, family 2
PG1C_RS11255	COG0463	Glycosyl transferase, family 2
PG1C_RS11255	COG1216	Glycosyl transferase, family 2
PG1C_RS11270	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
PG1C_RS11270	COG0546	phosphoglycolate phosphatase activity
PG1C_RS11330	COG0297	glycogen (starch) synthase activity
PG1C_RS11355	COG3267	Type II secretory pathway component ExeA
PG1C_RS11355	COG3409	Peptidoglycan-binding domain 1 protein
PG1C_RS11365	COG0489	protein tyrosine kinase activity
PG1C_RS11390	COG2301	Belongs to the HpcH HpaI aldolase family
PG1C_RS11405	COG1960	acyl-CoA dehydrogenase activity
PG1C_RS11410	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
PG1C_RS11415	COG0183	Belongs to the thiolase family
PG1C_RS11420	COG1028	Short-chain dehydrogenase reductase Sdr
PG1C_RS11440	COG1024	Enoyl-CoA hydratase
PG1C_RS11450	COG0163	prenyltransferase activity
PG1C_RS11465	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
PG1C_RS11470	COG1012	belongs to the aldehyde dehydrogenase family
PG1C_RS11495	COG1132	(ABC) transporter
PG1C_RS11500	COG0297	glycogen (starch) synthase activity
PG1C_RS11505	COG0726	polysaccharide deacetylase
PG1C_RS11525	COG0183	Belongs to the thiolase family
PG1C_RS11555	COG1024	Enoyl-CoA hydratase
PG1C_RS11565	COG0488	(ABC) transporter
PG1C_RS11575	COG2814	Major facilitator Superfamily
PG1C_RS11620	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
PG1C_RS11625	COG4115	mRNA cleavage
PG1C_RS11630	COG2161	toxin-antitoxin pair type II binding
PG1C_RS11660	COG3161	chorismate lyase activity
PG1C_RS11665	COG2096	Adenosyltransferase
PG1C_RS11670	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PG1C_RS11685	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
PG1C_RS11690	COG1185	polyribonucleotide nucleotidyltransferase activity
PG1C_RS11695	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PG1C_RS11700	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PG1C_RS11705	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PG1C_RS11710	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PG1C_RS11715	COG0195	Participates in both transcription termination and antitermination
PG1C_RS11715	COG2251	uridine kinase activity
PG1C_RS11720	COG0779	Required for maturation of 30S ribosomal subunits
PG1C_RS11725	COG1187	pseudouridine synthase activity
PG1C_RS11730	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PG1C_RS11740	COG0180	Tryptophanyl-tRNA synthetase
PG1C_RS11745	COG1994	Peptidase M50
PG1C_RS11750	COG0009	L-threonylcarbamoyladenylate synthase
PG1C_RS11755	COG0613	PHP domain protein
PG1C_RS11790	COG4638	Rieske (2fe-2S)
PG1C_RS11795	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
PG1C_RS11835	COG3158	transport of potassium into the cell
PG1C_RS11840	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
PG1C_RS11845	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
PG1C_RS11855	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
PG1C_RS11860	COG4208	sulfate ABC transporter
PG1C_RS11870	COG0583	DNA-binding transcription factor activity
PG1C_RS11875	COG1473	amidohydrolase
PG1C_RS11880	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PG1C_RS11890	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
PG1C_RS11895	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
PG1C_RS11905	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
PG1C_RS11920	COG0305	Participates in initiation and elongation during chromosome replication
PG1C_RS11925	COG0359	binds to the 23S rRNA
PG1C_RS11930	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PG1C_RS11940	COG0360	Binds together with S18 to 16S ribosomal RNA
PG1C_RS11945	COG1420	regulation of RNA biosynthetic process
PG1C_RS11950	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
PG1C_RS11955	COG0495	leucyl-tRNA aminoacylation
PG1C_RS11965	COG1466	dna polymerase III delta subunit
PG1C_RS11970	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PG1C_RS11990	COG0501	Belongs to the peptidase M48B family
PG1C_RS11995	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
PG1C_RS12000	COG0114	fumarate hydratase activity
PG1C_RS12010	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
PG1C_RS12015	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PG1C_RS12020	COG0726	polysaccharide deacetylase
PG1C_RS12030	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PG1C_RS12030	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PG1C_RS12040	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
PG1C_RS12045	COG2076	Multidrug Resistance protein
PG1C_RS12050	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PG1C_RS12060	COG0436	Aminotransferase
PG1C_RS12070	COG0346	lactoylglutathione lyase activity
PG1C_RS12095	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PG1C_RS12100	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PG1C_RS12105	COG1862	Preprotein translocase
PG1C_RS12110	COG0343	queuine tRNA-ribosyltransferase activity
PG1C_RS12115	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PG1C_RS12120	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PG1C_RS12125	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
PG1C_RS12135	COG0330	HflC and HflK could
PG1C_RS12140	COG0330	HflC and HflK could
PG1C_RS12145	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PG1C_RS12150	COG1923	regulation of RNA biosynthetic process
PG1C_RS12155	COG1160	GTP binding
PG1C_RS12160	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PG1C_RS12170	COG0124	histidyl-tRNA synthetase
PG1C_RS12175	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
PG1C_RS12190	COG0820	rRNA (adenine-C2-)-methyltransferase activity
PG1C_RS12195	COG0105	UTP biosynthetic process
PG1C_RS12200	COG0037	tRNA processing
PG1C_RS12205	COG0825	malonyl-CoA metabolic process
PG1C_RS12235	COG0167	dihydroorotate dehydrogenase activity
PG1C_RS12245	COG2878	Part of a membrane complex involved in electron transport
PG1C_RS12265	COG4660	Part of a membrane complex involved in electron transport
PG1C_RS12270	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PG1C_RS12285	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PG1C_RS12295	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PG1C_RS12305	COG0326	Molecular chaperone. Has ATPase activity
PG1C_RS12310	COG0243	molybdopterin cofactor binding
PG1C_RS12320	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PG1C_RS12325	COG0515	serine threonine protein kinase
PG1C_RS12330	COG2223	nitrite transmembrane transporter activity
PG1C_RS12340	COG1116	anion transmembrane transporter activity
PG1C_RS12345	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PG1C_RS12350	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PG1C_RS12365	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PG1C_RS12370	COG1518	maintenance of DNA repeat elements
PG1C_RS12415	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PG1C_RS12420	COG4783	chaperone-mediated protein folding
PG1C_RS12425	COG0315	cyclic pyranopterin monophosphate synthase activity
PG1C_RS12430	COG1612	heme a metabolic process
PG1C_RS12445	COG0501	Belongs to the peptidase M48B family
PG1C_RS12450	COG2974	May be involved in recombination
PG1C_RS12455	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
PG1C_RS12465	COG3145	DNA-N1-methyladenine dioxygenase activity
PG1C_RS12470	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PG1C_RS12470	COG2169	Transcriptional regulator
PG1C_RS12475	COG1674	ftsk spoiiie
PG1C_RS12480	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
PG1C_RS12490	COG0469	pyruvate kinase activity
PG1C_RS12495	COG0126	phosphoglycerate kinase activity
PG1C_RS12500	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PG1C_RS12505	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PG1C_RS12510	COG2032	superoxide dismutase activity
PG1C_RS12520	COG1040	competence protein
PG1C_RS12525	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
PG1C_RS12530	COG2226	methyltransferase
PG1C_RS12540	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
PG1C_RS12545	COG0508	dehydrogenase complex catalyzes the overall conversion of
PG1C_RS12550	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PG1C_RS12555	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PG1C_RS12570	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
PG1C_RS12570	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
PG1C_RS12580	COG1385	rRNA (uridine-N3-)-methyltransferase activity
PG1C_RS12605	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
PG1C_RS12610	COG0583	DNA-binding transcription factor activity
PG1C_RS12615	COG0730	response to heat
PG1C_RS12620	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PG1C_RS12630	COG0175	sulfate reduction
PG1C_RS12635	COG0175	sulfate reduction
PG1C_RS12640	COG2895	sulfate adenylyltransferase (ATP) activity
PG1C_RS12645	COG0203	ribosomal protein L17
PG1C_RS12650	COG0202	RNA polymerase activity
PG1C_RS12655	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PG1C_RS12660	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PG1C_RS12665	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PG1C_RS12670	COG0257	Belongs to the bacterial ribosomal protein bL36 family
PG1C_RS12675	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PG1C_RS12680	COG0201	protein transport
PG1C_RS12690	COG1841	ribosomal large subunit assembly
PG1C_RS12695	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PG1C_RS12700	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PG1C_RS12705	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PG1C_RS12710	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PG1C_RS12715	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PG1C_RS12720	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PG1C_RS12725	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PG1C_RS12730	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PG1C_RS12735	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PG1C_RS12740	COG0255	Belongs to the universal ribosomal protein uL29 family
PG1C_RS12745	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PG1C_RS12755	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PG1C_RS12760	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PG1C_RS12765	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PG1C_RS12770	COG0089	rRNA binding
PG1C_RS12775	COG0088	Forms part of the polypeptide exit tunnel
PG1C_RS12780	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PG1C_RS12785	COG0051	transcription antitermination factor activity, RNA binding
PG1C_RS12790	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PG1C_RS12795	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PG1C_RS12800	COG0049	tRNA binding
PG1C_RS12805	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PG1C_RS12810	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PG1C_RS12815	COG0085	RNA polymerase activity
PG1C_RS12820	COG0222	ribosome binding
PG1C_RS12825	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PG1C_RS12830	COG0081	regulation of translation
PG1C_RS12835	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PG1C_RS12855	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PG1C_RS12875	COG0277	FAD linked oxidase domain protein
PG1C_RS12890	COG1250	3-hydroxyacyl-CoA dehydrogenase
PG1C_RS12895	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PG1C_RS12895	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PG1C_RS12895	COG1703	isobutyryl-CoA mutase activity
PG1C_RS12905	COG3945	hemerythrin HHE cation binding domain
PG1C_RS12915	COG3744	PilT protein domain protein
PG1C_RS12930	COG1132	(ABC) transporter
PG1C_RS12935	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
PG1C_RS12940	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
PG1C_RS12945	COG3639	organic phosphonate transmembrane transporter activity
PG1C_RS12965	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PG1C_RS12975	COG0067	glutamate synthase
PG1C_RS12975	COG0070	glutamate synthase
PG1C_RS12975	COG0069	glutamate synthase activity
PG1C_RS12980	COG0232	Belongs to the dGTPase family. Type 2 subfamily
PG1C_RS12985	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PG1C_RS13025	COG1965	Belongs to the frataxin family
PG1C_RS13035	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PG1C_RS13040	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PG1C_RS13070	COG0534	Mate efflux family protein
PG1C_RS13110	COG0583	DNA-binding transcription factor activity
PG1C_RS13120	COG0247	lactate metabolic process
PG1C_RS13130	COG0783	Belongs to the Dps family
PG1C_RS13140	COG4681	YaeQ
PG1C_RS13145	COG0513	Belongs to the DEAD box helicase family
PG1C_RS13150	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PG1C_RS13155	COG1522	sequence-specific DNA binding
PG1C_RS13165	COG0513	Belongs to the DEAD box helicase family
PG1C_RS13170	COG1802	Transcriptional regulator
PG1C_RS13175	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PG1C_RS13175	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PG1C_RS13180	COG1703	isobutyryl-CoA mutase activity
PG1C_RS13185	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PG1C_RS13190	COG4770	biotin carboxylase activity
PG1C_RS13205	COG0840	transmembrane signaling receptor activity
PG1C_RS13225	COG1773	rubredoxin
PG1C_RS13230	COG0351	phosphomethylpyrimidine kinase
PG1C_RS13235	COG0352	thiamine-phosphate diphosphorylase activity
PG1C_RS13240	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
PG1C_RS13250	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PG1C_RS13255	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PG1C_RS13275	COG3150	esterase
PG1C_RS13280	COG1968	undecaprenyl-diphosphatase activity
PG1C_RS13285	COG1487	ribonuclease activity
PG1C_RS13295	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
PG1C_RS13315	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
PG1C_RS13325	COG1538	Outer membrane efflux protein
PG1C_RS13335	COG0859	PFAM glycosyl transferase family 9
PG1C_RS13350	COG0288	reversible hydration of carbon dioxide
PG1C_RS13385	COG0347	Belongs to the P(II) protein family
PG1C_RS13390	COG0004	ammonium transporteR
PG1C_RS13400	COG1970	mechanosensitive ion channel activity
PG1C_RS13405	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PG1C_RS13410	COG0415	Belongs to the DNA photolyase family
PG1C_RS13415	COG1678	Uncharacterized ACR, COG1678
PG1C_RS13420	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PG1C_RS13430	COG0540	Belongs to the ATCase OTCase family
PG1C_RS13435	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
PG1C_RS13440	COG1872	DUF167
PG1C_RS13480	COG1981	membrane
PG1C_RS13525	COG1331	Highly conserved protein containing a thioredoxin domain
PG1C_RS13550	COG0828	Belongs to the bacterial ribosomal protein bS21 family
PG1C_RS13555	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PG1C_RS13560	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
PG1C_RS13570	COG4974	Belongs to the 'phage' integrase family
PG1C_RS13590	COG0584	glycerophosphoryl diester phosphodiesterase
PG1C_RS13640	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PG1C_RS13650	COG1595	DNA-templated transcription, initiation
PG1C_RS13680	COG0429	hydrolase of the alpha beta-hydrolase fold
PG1C_RS13690	COG0859	PFAM glycosyl transferase family 9
PG1C_RS13715	COG0482	sulfurtransferase activity
PG1C_RS13735	COG0802	atpase or kinase
PG1C_RS13740	COG0860	N-Acetylmuramoyl-L-alanine amidase
PG1C_RS13745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PG1C_RS13750	COG0196	riboflavin kinase activity
PG1C_RS13755	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PG1C_RS13760	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PG1C_RS13765	COG1047	Peptidyl-prolyl cis-trans
PG1C_RS13770	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
PG1C_RS13850	COG2608	mercury ion transmembrane transporter activity
PG1C_RS13865	COG1012	belongs to the aldehyde dehydrogenase family
PG1C_RS13870	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
PG1C_RS13875	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PG1C_RS13875	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
PG1C_RS13880	COG0347	Belongs to the P(II) protein family
PG1C_RS13885	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PG1C_RS13890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PG1C_RS13915	COG2840	Smr protein MutS2
PG1C_RS13920	COG0492	ferredoxin-NADP+ reductase activity
PG1C_RS13950	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PG1C_RS13960	COG3118	belongs to the thioredoxin family
PG1C_RS13970	COG0788	formyltetrahydrofolate deformylase activity
PG1C_RS13980	COG0745	RESPONSE REGULATOR receiver
PG1C_RS13995	COG2982	Protein involved in outer membrane biogenesis
PG1C_RS14050	COG2826	transposase and inactivated derivatives, IS30 family
PG1C_RS14055	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
PG1C_RS14065	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
PG1C_RS14070	COG0363	glucosamine-6-phosphate deaminase activity
PG1C_RS14085	COG0166	Belongs to the GPI family
PG1C_RS14105	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
PG1C_RS14130	COG3237	CsbD-like
PG1C_RS14180	COG0753	catalase activity
PG1C_RS14185	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
PG1C_RS14195	COG3459	Glycosyltransferase 36 associated
PG1C_RS14200	COG0628	permease
PG1C_RS14205	COG2823	Periplasmic or secreted lipoprotein
PG1C_RS14220	COG1024	Enoyl-CoA hydratase
PG1C_RS14225	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PG1C_RS14230	COG0129	dihydroxy-acid dehydratase activity
PG1C_RS14235	COG0746	molybdenum cofactor guanylyltransferase activity
PG1C_RS14250	COG0424	maF-like protein
PG1C_RS14255	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PG1C_RS14260	COG0799	negative regulation of ribosome biogenesis
PG1C_RS14265	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PG1C_RS14275	COG0037	tRNA processing
PG1C_RS14280	COG1028	Short-chain dehydrogenase reductase Sdr
PG1C_RS14285	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
PG1C_RS14300	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PG1C_RS14305	COG4569	acetaldehyde dehydrogenase (acetylating) activity
PG1C_RS14310	COG1028	Short-chain dehydrogenase reductase Sdr
PG1C_RS14335	COG2922	Belongs to the Smg family
PG1C_RS14340	COG0758	DNA mediated transformation
PG1C_RS14350	COG0242	peptide deformylase activity
PG1C_RS14355	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PG1C_RS14365	COG0501	Belongs to the peptidase M48B family
PG1C_RS14370	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PG1C_RS14370	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PG1C_RS14385	COG2204	response regulator
PG1C_RS14390	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
PG1C_RS14395	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PG1C_RS14405	COG2226	methyltransferase
PG1C_RS14425	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
PG1C_RS14430	COG0355	proton-transporting ATP synthase activity, rotational mechanism
PG1C_RS14435	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PG1C_RS14440	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PG1C_RS14445	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PG1C_RS14450	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PG1C_RS14455	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PG1C_RS14465	COG0356	it plays a direct role in the translocation of protons across the membrane
PG1C_RS14475	COG1475	DNA binding
PG1C_RS14480	COG1192	Involved in chromosome partitioning
PG1C_RS14485	COG0357	Ribosomal RNA small subunit methyltransferase G
PG1C_RS14490	COG0445	tRNA wobble uridine modification
PG1C_RS14495	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PG1C_RS14500	COG0706	membrane insertase activity
PG1C_RS14505	COG0759	Could be involved in insertion of integral membrane proteins into the membrane