locus-tag	class	description
EHE19_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EHE19_RS00010	COG0592	DNA-directed DNA polymerase activity
EHE19_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EHE19_RS00030	COG0187	DNA topoisomerase II activity
EHE19_RS00035	COG1192	Involved in chromosome partitioning
EHE19_RS00040	COG1475	DNA binding
EHE19_RS00065	COG1183	phosphatidylcholine synthase activity
EHE19_RS00070	COG0546	phosphoglycolate phosphatase activity
EHE19_RS00090	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EHE19_RS00095	COG2759	Belongs to the formate--tetrahydrofolate ligase family
EHE19_RS00110	COG1388	LysM domain
EHE19_RS00115	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EHE19_RS00120	COG1802	Transcriptional regulator
EHE19_RS00125	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EHE19_RS00155	COG0736	holo-[acyl-carrier-protein] synthase activity
EHE19_RS00165	COG4717	serine-type aminopeptidase activity
EHE19_RS00170	COG0791	NLP P60 protein
EHE19_RS00175	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EHE19_RS00185	COG2959	enzyme of heme biosynthesis
EHE19_RS00230	COG4166	transmembrane transport
EHE19_RS00235	COG4608	Belongs to the ABC transporter superfamily
EHE19_RS00240	COG0444	Belongs to the ABC transporter superfamily
EHE19_RS00245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHE19_RS00250	COG0601	transmembrane transport
EHE19_RS00260	COG1078	dGTPase activity
EHE19_RS00270	COG1172	Belongs to the binding-protein-dependent transport system permease family
EHE19_RS00275	COG1172	Belongs to the binding-protein-dependent transport system permease family
EHE19_RS00285	COG4213	ABC transporter substrate-binding protein
EHE19_RS00290	COG1879	ABC-type sugar transport system periplasmic component
EHE19_RS00295	COG2972	Histidine kinase
EHE19_RS00300	COG2207	Transcriptional regulator
EHE19_RS00300	COG4753	response regulator
EHE19_RS00305	COG3534	alpha-L-arabinofuranosidase
EHE19_RS00315	COG0535	radical SAM domain protein
EHE19_RS00320	COG1132	(ABC) transporter
EHE19_RS00325	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EHE19_RS00350	COG1131	(ABC) transporter
EHE19_RS00360	COG1597	lipid kinase activity
EHE19_RS00365	COG0420	3'-5' exonuclease activity
EHE19_RS00370	COG0419	ATPase involved in DNA repair
EHE19_RS00395	COG1321	iron dependent repressor
EHE19_RS00420	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EHE19_RS00420	COG1918	ferrous iron import across plasma membrane
EHE19_RS00440	COG0535	radical SAM domain protein
EHE19_RS00460	COG1032	radical SAM domain protein
EHE19_RS00465	COG2226	methyltransferase
EHE19_RS00470	COG1131	(ABC) transporter
EHE19_RS00480	COG1032	radical SAM domain protein
EHE19_RS00505	COG0406	alpha-ribazole phosphatase activity
EHE19_RS00510	COG0352	thiamine-phosphate diphosphorylase activity
EHE19_RS00510	COG0351	phosphomethylpyrimidine kinase
EHE19_RS00515	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EHE19_RS00520	COG0352	thiamine-phosphate diphosphorylase activity
EHE19_RS00530	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EHE19_RS00535	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHE19_RS00540	COG1120	ATPase activity
EHE19_RS00545	COG1492	cobalamin metabolic process
EHE19_RS00555	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EHE19_RS00560	COG0360	Binds together with S18 to 16S ribosomal RNA
EHE19_RS00565	COG0629	single-stranded DNA binding
EHE19_RS00570	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EHE19_RS00580	COG1113	amino acid transport
EHE19_RS00590	COG1605	Chorismate mutase
EHE19_RS00590	COG0077	Prephenate dehydratase
EHE19_RS00600	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EHE19_RS00605	COG0359	binds to the 23S rRNA
EHE19_RS00610	COG0305	Participates in initiation and elongation during chromosome replication
EHE19_RS00615	COG0037	tRNA processing
EHE19_RS00620	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EHE19_RS00625	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EHE19_RS00635	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EHE19_RS00640	COG5492	domain, Protein
EHE19_RS00650	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EHE19_RS00655	COG1040	competence protein
EHE19_RS00685	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHE19_RS00695	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
EHE19_RS00700	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EHE19_RS00710	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EHE19_RS00720	COG2604	Protein of unknown function DUF115
EHE19_RS00730	COG1086	Polysaccharide biosynthesis protein
EHE19_RS00735	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EHE19_RS00740	COG0656	L-ascorbic acid biosynthetic process
EHE19_RS00745	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EHE19_RS00750	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
EHE19_RS00755	COG2089	acid synthase
EHE19_RS00760	COG0456	acetyltransferase
EHE19_RS00765	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EHE19_RS00770	COG0363	glucosamine-6-phosphate deaminase activity
EHE19_RS00780	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EHE19_RS00790	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EHE19_RS00795	COG1516	flagellar protein fliS
EHE19_RS00875	COG0488	(ABC) transporter
EHE19_RS00885	COG2207	Transcriptional regulator
EHE19_RS00890	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EHE19_RS00895	COG0066	3-isopropylmalate dehydratase activity
EHE19_RS00900	COG0473	3-isopropylmalate dehydrogenase activity
EHE19_RS00905	COG2409	Drug exporters of the RND superfamily
EHE19_RS00915	COG0745	RESPONSE REGULATOR receiver
EHE19_RS00920	COG4251	negative regulation of phosphorylation
EHE19_RS00930	COG4242	Belongs to the peptidase S51 family
EHE19_RS00935	COG1181	Belongs to the D-alanine--D-alanine ligase family
EHE19_RS00935	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EHE19_RS00945	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EHE19_RS00945	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EHE19_RS00955	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EHE19_RS00965	COG0281	malic enzyme
EHE19_RS00970	COG2207	Transcriptional regulator
EHE19_RS00970	COG4753	response regulator
EHE19_RS00970	COG2207	Transcriptional regulator
EHE19_RS00970	COG4753	response regulator
EHE19_RS00975	COG2972	Histidine kinase
EHE19_RS00980	COG2207	Transcriptional regulator
EHE19_RS00980	COG4753	response regulator
EHE19_RS00990	COG4209	transmembrane transport
EHE19_RS00995	COG0395	ABC-type sugar transport system, permease component
EHE19_RS01010	COG0778	Nitroreductase
EHE19_RS01015	COG2197	response regulator
EHE19_RS01020	COG4585	Histidine kinase
EHE19_RS01025	COG4166	transmembrane transport
EHE19_RS01060	COG1982	Orn Lys Arg decarboxylase major
EHE19_RS01070	COG3870	Protein conserved in bacteria
EHE19_RS01080	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EHE19_RS01085	COG1774	PSP1 C-terminal conserved region
EHE19_RS01090	COG2221	Nitrite and sulphite reductase 4Fe-4S
EHE19_RS01095	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EHE19_RS01100	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EHE19_RS01105	COG2002	toxin-antitoxin pair type II binding
EHE19_RS01110	COG2715	membrane protein required for spore maturation
EHE19_RS01115	COG0700	Nucleoside recognition
EHE19_RS01125	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EHE19_RS01125	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EHE19_RS01130	COG0084	hydrolase, TatD family'
EHE19_RS01140	COG3583	domain protein
EHE19_RS01140	COG3584	3D domain protein
EHE19_RS01145	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EHE19_RS01155	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EHE19_RS01160	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EHE19_RS01165	COG0826	peptidase U32
EHE19_RS01175	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EHE19_RS01185	COG1739	Uncharacterized protein family UPF0029
EHE19_RS01190	COG0217	transcriptional regulatory protein
EHE19_RS01205	COG0628	permease
EHE19_RS01215	COG2155	Conserved Protein
EHE19_RS01240	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
EHE19_RS01245	COG0347	Belongs to the P(II) protein family
EHE19_RS01250	COG0347	Belongs to the P(II) protein family
EHE19_RS01285	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EHE19_RS01290	COG0725	ABC transporter, periplasmic molybdate-binding protein
EHE19_RS01295	COG4149	molybdate abc transporter
EHE19_RS01305	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EHE19_RS01310	COG0785	Cytochrome C biogenesis protein
EHE19_RS01320	COG1472	Belongs to the glycosyl hydrolase 3 family
EHE19_RS01325	COG2873	o-acetylhomoserine
EHE19_RS01330	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EHE19_RS01355	COG1045	serine acetyltransferase
EHE19_RS01360	COG0215	cysteine-tRNA ligase activity
EHE19_RS01370	COG0708	Exodeoxyribonuclease III
EHE19_RS01380	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EHE19_RS01415	COG3290	protein histidine kinase activity
EHE19_RS01440	COG2002	toxin-antitoxin pair type II binding
EHE19_RS01460	COG1475	DNA binding
EHE19_RS01520	COG0582	viral genome integration into host DNA
EHE19_RS01705	COG0515	serine threonine protein kinase
EHE19_RS01705	COG2815	serine threonine protein kinase
EHE19_RS01710	COG2197	response regulator
EHE19_RS01715	COG1191	sigma factor activity
EHE19_RS01725	COG5297	Belongs to the glycosyl hydrolase family 6
EHE19_RS01735	COG4733	cellulase activity
EHE19_RS01740	COG2273	Hydrolase Family 16
EHE19_RS01740	COG5297	Belongs to the glycosyl hydrolase family 6
EHE19_RS01755	COG4733	cellulase activity
EHE19_RS01760	COG4733	cellulase activity
EHE19_RS01785	COG5297	Belongs to the glycosyl hydrolase family 6
EHE19_RS01790	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EHE19_RS01800	COG5297	Belongs to the glycosyl hydrolase family 6
EHE19_RS01810	COG2911	Protein conserved in bacteria
EHE19_RS01865	COG1396	sequence-specific DNA binding
EHE19_RS01885	COG2003	Belongs to the UPF0758 family
EHE19_RS01930	COG1132	(ABC) transporter
EHE19_RS01960	COG1404	Belongs to the peptidase S8 family
EHE19_RS01970	COG1132	(ABC) transporter
EHE19_RS02000	COG4585	Histidine kinase
EHE19_RS02005	COG2197	response regulator
EHE19_RS02020	COG1175	transmembrane transport
EHE19_RS02025	COG0395	ABC-type sugar transport system, permease component
EHE19_RS02050	COG1388	LysM domain
EHE19_RS02050	COG3858	chitin binding
EHE19_RS02055	COG2252	PERMEase
EHE19_RS02065	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
EHE19_RS02070	COG0300	oxidoreductase activity
EHE19_RS02080	COG0840	transmembrane signaling receptor activity
EHE19_RS02090	COG2201	protein-glutamate methylesterase activity
EHE19_RS02095	COG2207	Transcriptional regulator
EHE19_RS02100	COG1904	glucuronate isomerase
EHE19_RS02105	COG0800	Aldolase
EHE19_RS02120	COG0246	Mannitol dehydrogenase
EHE19_RS02125	COG1312	Catalyzes the dehydration of D-mannonate
EHE19_RS02135	COG2207	Transcriptional regulator
EHE19_RS02135	COG0662	Cupin 2, conserved barrel domain protein
EHE19_RS02140	COG4209	transmembrane transport
EHE19_RS02145	COG0395	ABC-type sugar transport system, permease component
EHE19_RS02220	COG0251	oxidation-reduction process
EHE19_RS02240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHE19_RS02295	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EHE19_RS02310	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EHE19_RS02315	COG0025	NhaP-type Na H and K H
EHE19_RS02320	COG2357	RelA SpoT domain protein
EHE19_RS02325	COG0860	N-Acetylmuramoyl-L-alanine amidase
EHE19_RS02335	COG0159	tryptophan synthase activity
EHE19_RS02340	COG0133	tryptophan synthase activity
EHE19_RS02350	COG0134	indole-3-glycerol-phosphate synthase activity
EHE19_RS02355	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EHE19_RS02360	COG0512	Glutamine amidotransferase of anthranilate synthase
EHE19_RS02360	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EHE19_RS02390	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
EHE19_RS02390	COG2199	diguanylate cyclase activity
EHE19_RS02415	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EHE19_RS02420	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
EHE19_RS02425	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
EHE19_RS02445	COG1454	alcohol dehydrogenase
EHE19_RS02445	COG1012	belongs to the aldehyde dehydrogenase family
EHE19_RS02455	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EHE19_RS02465	COG1609	Transcriptional regulator
EHE19_RS02500	COG4786	Flagellar basal body rod
EHE19_RS02510	COG3951	Flagellar rod assembly protein muramidase FlgJ
EHE19_RS02520	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EHE19_RS02525	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EHE19_RS02530	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EHE19_RS02535	COG2088	sporulation resulting in formation of a cellular spore
EHE19_RS02540	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EHE19_RS02550	COG0193	aminoacyl-tRNA hydrolase activity
EHE19_RS02555	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EHE19_RS02565	COG2002	toxin-antitoxin pair type II binding
EHE19_RS02570	COG0629	single-stranded DNA binding
EHE19_RS02575	COG3956	TIGRFAM MazG family protein
EHE19_RS02585	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EHE19_RS02605	COG1098	S1 RNA binding domain
EHE19_RS02615	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EHE19_RS02620	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EHE19_RS02645	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EHE19_RS02660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EHE19_RS02675	COG1609	Transcriptional regulator
EHE19_RS02680	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EHE19_RS02705	COG1671	Belongs to the UPF0178 family
EHE19_RS02715	COG1550	Protein conserved in bacteria
EHE19_RS02720	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EHE19_RS02740	COG2207	Transcriptional regulator
EHE19_RS02740	COG1917	Cupin 2, conserved barrel domain protein
EHE19_RS02770	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EHE19_RS02775	COG2208	phosphoserine phosphatase activity
EHE19_RS02800	COG3345	alpha-galactosidase
EHE19_RS02870	COG2207	Transcriptional regulator
EHE19_RS02870	COG3708	Transcriptional regulator
EHE19_RS02875	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EHE19_RS02880	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EHE19_RS02885	COG0860	N-Acetylmuramoyl-L-alanine amidase
EHE19_RS02890	COG0791	NLP P60 protein
EHE19_RS02890	COG1388	LysM domain
EHE19_RS02895	COG2244	polysaccharide biosynthetic process
EHE19_RS02900	COG0071	Belongs to the small heat shock protein (HSP20) family
EHE19_RS02950	COG1216	Glycosyl transferase, family 2
EHE19_RS02965	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EHE19_RS02965	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EHE19_RS02970	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EHE19_RS02975	COG0864	Transcriptional regulator
EHE19_RS02980	COG2337	Toxic component of a toxin-antitoxin (TA) module
EHE19_RS02995	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
EHE19_RS03005	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EHE19_RS03010	COG0840	transmembrane signaling receptor activity
EHE19_RS03020	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EHE19_RS03025	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EHE19_RS03035	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EHE19_RS03040	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EHE19_RS03045	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EHE19_RS03050	COG3842	ATPase activity
EHE19_RS03060	COG3835	regulator
EHE19_RS03065	COG2884	Cell division ATP-binding protein ftsE
EHE19_RS03070	COG2177	Part of the ABC transporter FtsEX involved in
EHE19_RS03075	COG0739	heme binding
EHE19_RS03080	COG0793	Belongs to the peptidase S41A family
EHE19_RS03080	COG3409	Peptidoglycan-binding domain 1 protein
EHE19_RS03095	COG1278	Cold shock
EHE19_RS03100	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EHE19_RS03130	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EHE19_RS03140	COG4447	cellulose binding
EHE19_RS03145	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EHE19_RS03160	COG0860	N-Acetylmuramoyl-L-alanine amidase
EHE19_RS03165	COG0488	(ABC) transporter
EHE19_RS03175	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EHE19_RS03180	COG0287	Prephenate dehydrogenase
EHE19_RS03185	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EHE19_RS03190	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EHE19_RS03200	COG3880	PFAM UvrB UvrC protein
EHE19_RS03205	COG3869	Catalyzes the specific phosphorylation of arginine residues in
EHE19_RS03210	COG0542	response to heat
EHE19_RS03230	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EHE19_RS03245	COG1329	Transcriptional regulator
EHE19_RS03250	COG4956	integral membrane protein (PIN domain superfamily)
EHE19_RS03255	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EHE19_RS03260	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EHE19_RS03265	COG2340	Cysteine-rich secretory protein family
EHE19_RS03270	COG0564	pseudouridine synthase activity
EHE19_RS03275	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EHE19_RS03300	COG1105	Belongs to the carbohydrate kinase PfkB family
EHE19_RS03305	COG2183	response to ionizing radiation
EHE19_RS03335	COG0492	ferredoxin-NADP+ reductase activity
EHE19_RS03345	COG5401	PFAM Sporulation and spore germination
EHE19_RS03355	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EHE19_RS03370	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EHE19_RS03385	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EHE19_RS03390	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EHE19_RS03590	COG2274	protein secretion by the type I secretion system
EHE19_RS03595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHE19_RS03600	COG0210	DNA helicase
EHE19_RS03615	COG0583	DNA-binding transcription factor activity
EHE19_RS03630	COG0124	histidyl-tRNA synthetase
EHE19_RS03635	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EHE19_RS03640	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EHE19_RS03645	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EHE19_RS03650	COG0131	Imidazoleglycerol-phosphate dehydratase
EHE19_RS03660	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EHE19_RS03665	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EHE19_RS03670	COG0107	imidazoleglycerol-phosphate synthase activity
EHE19_RS03685	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EHE19_RS03690	COG0459	protein refolding
EHE19_RS03700	COG0516	GMP reductase activity
EHE19_RS03705	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EHE19_RS03710	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EHE19_RS03720	COG1366	Belongs to the anti-sigma-factor antagonist family
EHE19_RS03765	COG0051	transcription antitermination factor activity, RNA binding
EHE19_RS03770	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EHE19_RS03775	COG0088	Forms part of the polypeptide exit tunnel
EHE19_RS03780	COG0089	rRNA binding
EHE19_RS03785	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EHE19_RS03790	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EHE19_RS03795	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EHE19_RS03800	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EHE19_RS03805	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EHE19_RS03810	COG0255	Belongs to the universal ribosomal protein uL29 family
EHE19_RS03815	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EHE19_RS03820	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EHE19_RS03825	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EHE19_RS03830	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EHE19_RS03835	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EHE19_RS03840	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EHE19_RS03845	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EHE19_RS03850	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EHE19_RS03855	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EHE19_RS03860	COG1841	ribosomal large subunit assembly
EHE19_RS03865	COG0200	Binds to the 23S rRNA
EHE19_RS03870	COG0201	protein transport
EHE19_RS03875	COG0563	adenylate kinase activity
EHE19_RS03890	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EHE19_RS03900	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EHE19_RS03910	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EHE19_RS03915	COG0202	RNA polymerase activity
EHE19_RS03920	COG0203	ribosomal protein L17
EHE19_RS03925	COG1122	ATPase activity
EHE19_RS03930	COG2813	Specifically methylates the guanine in position
EHE19_RS03935	COG1122	ATPase activity
EHE19_RS03940	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EHE19_RS03945	COG0101	tRNA pseudouridine synthase activity
EHE19_RS03950	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EHE19_RS03955	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EHE19_RS03995	COG1914	H( )-stimulated, divalent metal cation uptake system
EHE19_RS04005	COG1228	amidohydrolase
EHE19_RS04010	COG0802	atpase or kinase
EHE19_RS04015	COG1214	PFAM Peptidase M22, glycoprotease
EHE19_RS04020	COG0456	acetyltransferase
EHE19_RS04025	COG1067	ATP-dependent peptidase activity
EHE19_RS04030	COG1595	DNA-templated transcription, initiation
EHE19_RS04050	COG0322	excinuclease ABC activity
EHE19_RS04060	COG0544	peptidyl-prolyl cis-trans isomerase activity
EHE19_RS04065	COG0740	serine-type endopeptidase activity
EHE19_RS04070	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EHE19_RS04075	COG0470	DNA polymerase III
EHE19_RS04075	COG1067	ATP-dependent peptidase activity
EHE19_RS04080	COG1525	nuclease
EHE19_RS04085	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EHE19_RS04090	COG0741	lytic transglycosylase activity
EHE19_RS04105	COG0613	PHP domain protein
EHE19_RS04110	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EHE19_RS04140	COG3177	Filamentation induced by cAMP protein fic
EHE19_RS04215	COG2207	Transcriptional regulator
EHE19_RS04215	COG1917	Cupin 2, conserved barrel domain protein
EHE19_RS04220	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EHE19_RS04235	COG1609	Transcriptional regulator
EHE19_RS04245	COG2094	Belongs to the DNA glycosylase MPG family
EHE19_RS04255	COG1335	isochorismatase
EHE19_RS04265	COG1690	Belongs to the RtcB family
EHE19_RS04295	COG2195	Cleaves the N-terminal amino acid of tripeptides
EHE19_RS04345	COG1472	Belongs to the glycosyl hydrolase 3 family
EHE19_RS04360	COG0562	UDP-galactopyranose mutase
EHE19_RS04365	COG0463	Glycosyl transferase, family 2
EHE19_RS04375	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EHE19_RS04380	COG1012	belongs to the aldehyde dehydrogenase family
EHE19_RS04385	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EHE19_RS04385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EHE19_RS04395	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EHE19_RS04420	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EHE19_RS04420	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EHE19_RS04425	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EHE19_RS04445	COG0542	response to heat
EHE19_RS04450	COG5002	protein histidine kinase activity
EHE19_RS04455	COG3033	Beta-eliminating lyase
EHE19_RS04490	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EHE19_RS04505	COG0371	Dehydrogenase
EHE19_RS04510	COG3706	GGDEF domain
EHE19_RS04520	COG0546	phosphoglycolate phosphatase activity
EHE19_RS04530	COG3326	Membrane
EHE19_RS04535	COG1716	ATPase activity
EHE19_RS04545	COG0768	penicillin binding
EHE19_RS04550	COG1649	PFAM Uncharacterised BCR, COG1649
EHE19_RS04555	COG2340	Cysteine-rich secretory protein family
EHE19_RS04560	COG2814	Major facilitator Superfamily
EHE19_RS04570	COG0646	methionine synthase
EHE19_RS04570	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EHE19_RS04580	COG0483	inositol monophosphate 1-phosphatase activity
EHE19_RS04585	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EHE19_RS04600	COG0681	Belongs to the peptidase S26 family
EHE19_RS04625	COG0492	ferredoxin-NADP+ reductase activity
EHE19_RS04640	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
EHE19_RS04650	COG0723	plastoquinol--plastocyanin reductase activity
EHE19_RS04650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EHE19_RS04670	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EHE19_RS04700	COG1175	transmembrane transport
EHE19_RS04705	COG0395	ABC-type sugar transport system, permease component
EHE19_RS04715	COG0367	asparagine synthase
EHE19_RS04725	COG0017	Asparaginyl-tRNA synthetase
EHE19_RS04730	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EHE19_RS04735	COG0154	amidase activity
EHE19_RS04740	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EHE19_RS04745	COG0067	glutamate synthase
EHE19_RS04750	COG0069	glutamate synthase activity
EHE19_RS04755	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EHE19_RS04775	COG3707	response regulator
EHE19_RS04780	COG0004	ammonium transporteR
EHE19_RS04785	COG0347	Belongs to the P(II) protein family
EHE19_RS04790	COG0010	Belongs to the arginase family
EHE19_RS04795	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EHE19_RS04800	COG0436	Aminotransferase
EHE19_RS04805	COG0546	phosphoglycolate phosphatase activity
EHE19_RS04810	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EHE19_RS04810	COG0116	Belongs to the methyltransferase superfamily
EHE19_RS04815	COG0564	pseudouridine synthase activity
EHE19_RS04820	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EHE19_RS04825	COG0116	Belongs to the methyltransferase superfamily
EHE19_RS04830	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EHE19_RS04835	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EHE19_RS04845	COG0745	RESPONSE REGULATOR receiver
EHE19_RS04875	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EHE19_RS04985	COG1674	ftsk spoiiie
EHE19_RS04995	COG3942	CHAP domain
EHE19_RS04995	COG1388	LysM domain
EHE19_RS05055	COG1573	uracil-dna glycosylase
EHE19_RS05065	COG2226	methyltransferase
EHE19_RS05120	COG0861	Integral membrane protein TerC family
EHE19_RS05140	COG1268	BioY protein
EHE19_RS05145	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EHE19_RS05155	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EHE19_RS05185	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EHE19_RS05190	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EHE19_RS05195	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EHE19_RS05200	COG1660	Displays ATPase and GTPase activities
EHE19_RS05205	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EHE19_RS05215	COG1481	regulation of sporulation
EHE19_RS05220	COG1366	Belongs to the anti-sigma-factor antagonist family
EHE19_RS05230	COG1191	sigma factor activity
EHE19_RS05245	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EHE19_RS05255	COG1406	Chemotaxis phosphatase CheX
EHE19_RS05275	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EHE19_RS05285	COG3290	protein histidine kinase activity
EHE19_RS05285	COG0840	transmembrane signaling receptor activity
EHE19_RS05295	COG0596	Alpha beta hydrolase
EHE19_RS05300	COG0596	Alpha beta hydrolase
EHE19_RS05310	COG0126	phosphoglycerate kinase activity
EHE19_RS05315	COG0149	triose-phosphate isomerase activity
EHE19_RS05320	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EHE19_RS05330	COG0148	phosphopyruvate hydratase activity
EHE19_RS05335	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EHE19_RS05345	COG0726	polysaccharide deacetylase
EHE19_RS05350	COG0745	RESPONSE REGULATOR receiver
EHE19_RS05355	COG5002	protein histidine kinase activity
EHE19_RS05365	COG0557	exoribonuclease II activity
EHE19_RS05380	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
EHE19_RS05385	COG4770	biotin carboxylase activity
EHE19_RS05400	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EHE19_RS05405	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EHE19_RS05410	COG4472	Bacterial protein of unknown function (DUF965)
EHE19_RS05415	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EHE19_RS05420	COG3906	Belongs to the UPF0473 family
EHE19_RS05430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHE19_RS05430	COG4191	Histidine kinase
EHE19_RS05465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EHE19_RS05505	COG1882	Formate acetyltransferase
EHE19_RS05510	COG0205	6-phosphofructokinase activity
EHE19_RS05515	COG0191	fructose-bisphosphate aldolase activity
EHE19_RS05530	COG1309	transcriptional regulator
EHE19_RS05550	COG1106	Psort location Cytoplasmic, score
EHE19_RS05580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EHE19_RS05585	COG1606	tRNA processing
EHE19_RS05590	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EHE19_RS05595	COG2011	ABC-type metal ion transport system permease component
EHE19_RS05600	COG1464	Belongs to the NlpA lipoprotein family
EHE19_RS05615	COG0726	polysaccharide deacetylase
EHE19_RS05620	COG0739	heme binding
EHE19_RS05625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHE19_RS05630	COG0765	amino acid transport
EHE19_RS05635	COG1126	abc transporter atp-binding protein
EHE19_RS05640	COG1592	Rubrerythrin
EHE19_RS05645	COG1272	protein, Hemolysin III
EHE19_RS05650	COG1022	Amp-dependent synthetase and ligase
EHE19_RS05655	COG1744	ABC transporter substrate-binding protein PnrA-like
EHE19_RS05660	COG3845	ABC transporter
EHE19_RS05665	COG4603	Belongs to the binding-protein-dependent transport system permease family
EHE19_RS05670	COG1079	Belongs to the binding-protein-dependent transport system permease family
EHE19_RS05675	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EHE19_RS05680	COG2733	membrane
EHE19_RS05685	COG1592	Rubrerythrin
EHE19_RS05685	COG1773	rubredoxin
EHE19_RS05745	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EHE19_RS05760	COG3842	ATPase activity
EHE19_RS05765	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EHE19_RS05775	COG4753	response regulator
EHE19_RS05775	COG2207	Transcriptional regulator
EHE19_RS05795	COG3708	Transcriptional regulator
EHE19_RS05795	COG2207	Transcriptional regulator
EHE19_RS05825	COG3959	Transketolase, thiamine diphosphate binding domain
EHE19_RS05830	COG3958	Transketolase
EHE19_RS05840	COG0318	PFAM AMP-dependent synthetase and ligase
EHE19_RS05855	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EHE19_RS05885	COG1151	hydroxylamine reductase activity
EHE19_RS05905	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EHE19_RS05910	COG0688	phosphatidylethanolamine metabolic process
EHE19_RS05930	COG1131	(ABC) transporter
EHE19_RS05945	COG1131	(ABC) transporter
EHE19_RS05950	COG1725	Transcriptional regulator
EHE19_RS05980	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EHE19_RS06020	COG1132	(ABC) transporter
EHE19_RS06035	COG1376	ErfK ybiS ycfS ynhG family protein
EHE19_RS06040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHE19_RS06045	COG0765	amino acid transport
EHE19_RS06055	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EHE19_RS06060	COG0501	Belongs to the peptidase M48B family
EHE19_RS06070	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EHE19_RS06075	COG3459	Glycosyltransferase 36 associated
EHE19_RS06080	COG0840	transmembrane signaling receptor activity
EHE19_RS06085	COG0538	isocitrate dehydrogenase activity
EHE19_RS06090	COG2502	aspartate--ammonia ligase
EHE19_RS06100	COG0653	protein targeting
EHE19_RS06105	COG0372	Belongs to the citrate synthase family
EHE19_RS06115	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EHE19_RS06120	COG0473	3-isopropylmalate dehydrogenase activity
EHE19_RS06140	COG4862	establishment of competence for transformation
EHE19_RS06145	COG0424	maF-like protein
EHE19_RS06150	COG2003	Belongs to the UPF0758 family
EHE19_RS06155	COG1077	Cell shape determining protein MreB Mrl
EHE19_RS06170	COG0768	penicillin binding
EHE19_RS06175	COG0850	regulation of cytokinetic process
EHE19_RS06180	COG2894	cell division
EHE19_RS06185	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EHE19_RS06245	COG0573	inorganic phosphate transmembrane transporter activity
EHE19_RS06250	COG0581	inorganic phosphate transmembrane transporter activity
EHE19_RS06255	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EHE19_RS06260	COG0704	Plays a role in the regulation of phosphate uptake
EHE19_RS06270	COG5002	protein histidine kinase activity
EHE19_RS06280	COG1994	Peptidase M50
EHE19_RS06290	COG0493	'glutamate synthase
EHE19_RS06310	COG0628	permease
EHE19_RS06315	COG0730	response to heat
EHE19_RS06320	COG0730	response to heat
EHE19_RS06325	COG0714	Associated with various cellular activities
EHE19_RS06360	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EHE19_RS06365	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EHE19_RS06380	COG1132	(ABC) transporter
EHE19_RS06405	COG0628	permease
EHE19_RS06425	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EHE19_RS06430	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EHE19_RS06430	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EHE19_RS06435	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EHE19_RS06445	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
EHE19_RS06450	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EHE19_RS06455	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EHE19_RS06550	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EHE19_RS06555	COG3507	Belongs to the glycosyl hydrolase 43 family
EHE19_RS06555	COG3693	PFAM glycoside hydrolase, family 10
EHE19_RS06555	COG2382	esterase
EHE19_RS06595	COG1486	melibiose metabolic process
EHE19_RS06600	COG1151	hydroxylamine reductase activity
EHE19_RS06605	COG0432	Pfam Uncharacterised protein family UPF0047
EHE19_RS06615	COG1396	sequence-specific DNA binding
EHE19_RS06620	COG1396	sequence-specific DNA binding
EHE19_RS06660	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EHE19_RS06670	COG1459	type II secretion system
EHE19_RS06680	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EHE19_RS06725	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EHE19_RS06735	COG2235	arginine
EHE19_RS06765	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EHE19_RS06795	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EHE19_RS06800	COG1063	alcohol dehydrogenase
EHE19_RS06815	COG4733	cellulase activity
EHE19_RS06820	COG4733	cellulase activity
EHE19_RS06820	COG4447	cellulose binding
EHE19_RS06825	COG4733	cellulase activity
EHE19_RS06825	COG4447	cellulose binding
EHE19_RS06840	COG3858	chitin binding
EHE19_RS06855	COG3693	PFAM glycoside hydrolase, family 10
EHE19_RS06885	COG2949	membrane
EHE19_RS06900	COG0840	transmembrane signaling receptor activity
EHE19_RS06910	COG2268	Band 7 protein
EHE19_RS06915	COG0577	efflux transmembrane transporter activity
EHE19_RS06925	COG1136	(ABC) transporter
EHE19_RS06935	COG0488	(ABC) transporter
EHE19_RS06950	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
EHE19_RS06960	COG1136	(ABC) transporter
EHE19_RS06965	COG1136	(ABC) transporter
EHE19_RS06965	COG0577	efflux transmembrane transporter activity
EHE19_RS06985	COG0187	DNA topoisomerase II activity
EHE19_RS06990	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EHE19_RS07000	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EHE19_RS07030	COG1971	Probably functions as a manganese efflux pump
EHE19_RS07035	COG0556	nucleotide-excision repair
EHE19_RS07040	COG1380	Effector of murein hydrolase LrgA
EHE19_RS07045	COG1346	cytolysis
EHE19_RS07055	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EHE19_RS07060	COG1408	metallophosphoesterase
EHE19_RS07075	COG4974	Belongs to the 'phage' integrase family
EHE19_RS07145	COG4733	cellulase activity
EHE19_RS07150	COG1609	Transcriptional regulator
EHE19_RS07155	COG1070	Carbohydrate kinase
EHE19_RS07160	COG1063	alcohol dehydrogenase
EHE19_RS07170	COG0656	L-ascorbic acid biosynthetic process
EHE19_RS07175	COG4154	Belongs to the RbsD FucU family
EHE19_RS07180	COG0745	RESPONSE REGULATOR receiver
EHE19_RS07180	COG2972	Histidine kinase
EHE19_RS07185	COG2197	response regulator
EHE19_RS07195	COG1175	transmembrane transport
EHE19_RS07200	COG0395	ABC-type sugar transport system, permease component
EHE19_RS07210	COG1501	Belongs to the glycosyl hydrolase 31 family
EHE19_RS07220	COG2078	PFAM AMMECR1 domain protein
EHE19_RS07220	COG3885	ferrous iron binding
EHE19_RS07270	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EHE19_RS07275	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EHE19_RS07285	COG2172	sigma factor antagonist activity
EHE19_RS07310	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EHE19_RS07315	COG1609	Transcriptional regulator
EHE19_RS07320	COG3459	Glycosyltransferase 36 associated
EHE19_RS07325	COG0778	Nitroreductase
EHE19_RS07340	COG3279	Response regulator of the LytR AlgR family
EHE19_RS07350	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EHE19_RS07355	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EHE19_RS07385	COG0596	Alpha beta hydrolase
EHE19_RS07405	COG0072	phenylalanine-tRNA ligase activity
EHE19_RS07425	COG0166	Belongs to the GPI family
EHE19_RS07445	COG1752	Esterase of the alpha-beta hydrolase superfamily
EHE19_RS07455	COG4492	Belongs to the UPF0735 family
EHE19_RS07460	COG0460	homoserine dehydrogenase
EHE19_RS07500	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EHE19_RS07510	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EHE19_RS07515	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EHE19_RS07520	COG1534	Rna-binding protein
EHE19_RS07535	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EHE19_RS07545	COG0297	glycogen (starch) synthase activity
EHE19_RS07595	COG0165	Argininosuccinate lyase
EHE19_RS07600	COG0137	argininosuccinate synthase activity
EHE19_RS07605	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EHE19_RS07610	COG0632	four-way junction helicase activity
EHE19_RS07615	COG2255	four-way junction helicase activity
EHE19_RS07620	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EHE19_RS07630	COG0860	N-Acetylmuramoyl-L-alanine amidase
EHE19_RS07640	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EHE19_RS07645	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EHE19_RS07675	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EHE19_RS07695	COG0840	transmembrane signaling receptor activity
EHE19_RS07700	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EHE19_RS07705	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EHE19_RS07710	COG1802	Transcriptional regulator
EHE19_RS07740	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
EHE19_RS07740	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EHE19_RS07745	COG1187	pseudouridine synthase activity
EHE19_RS07760	COG0726	polysaccharide deacetylase
EHE19_RS07765	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EHE19_RS07770	COG0402	S-adenosylhomocysteine deaminase activity
EHE19_RS07785	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EHE19_RS07800	COG3693	PFAM glycoside hydrolase, family 10
EHE19_RS07800	COG3507	Belongs to the glycosyl hydrolase 43 family
EHE19_RS07800	COG2382	esterase
EHE19_RS07805	COG2814	Major facilitator Superfamily
EHE19_RS07855	COG3291	Pkd domain containing protein
EHE19_RS07865	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
EHE19_RS07870	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EHE19_RS07890	COG0280	phosphate acetyltransferase
EHE19_RS07895	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EHE19_RS07905	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EHE19_RS07915	COG1160	GTP binding
EHE19_RS07920	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EHE19_RS07925	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EHE19_RS07930	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EHE19_RS07935	COG3859	Proton-coupled thiamine transporter YuaJ
EHE19_RS07945	COG1392	Phosphate transport regulator
EHE19_RS07950	COG0306	phosphate transporter
EHE19_RS07955	COG1392	Phosphate transport regulator
EHE19_RS07960	COG0306	phosphate transporter
EHE19_RS07965	COG0542	response to heat
EHE19_RS07970	COG1653	transport
EHE19_RS07975	COG2972	Histidine kinase
EHE19_RS07980	COG2207	Transcriptional regulator
EHE19_RS07980	COG4753	response regulator
EHE19_RS07980	COG2207	Transcriptional regulator
EHE19_RS07980	COG4753	response regulator
EHE19_RS07985	COG4209	transmembrane transport
EHE19_RS07990	COG0395	ABC-type sugar transport system, permease component
EHE19_RS08000	COG1609	Transcriptional regulator
EHE19_RS08005	COG3459	Glycosyltransferase 36 associated
EHE19_RS08010	COG5002	protein histidine kinase activity
EHE19_RS08015	COG0745	RESPONSE REGULATOR receiver
EHE19_RS08020	COG0835	chemotaxis
EHE19_RS08025	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EHE19_RS08030	COG0537	adenosine 5'-monophosphoramidase activity
EHE19_RS08035	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EHE19_RS08045	COG2954	triphosphatase activity
EHE19_RS08095	COG2323	membrane
EHE19_RS08100	COG0569	domain protein
EHE19_RS08125	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EHE19_RS08135	COG1595	DNA-templated transcription, initiation
EHE19_RS08145	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EHE19_RS08145	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EHE19_RS08150	COG0237	dephospho-CoA kinase activity
EHE19_RS08165	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EHE19_RS08170	COG3442	glutamine amidotransferase
EHE19_RS08175	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EHE19_RS08180	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EHE19_RS08190	COG3856	small basic protein
EHE19_RS08195	COG0849	cell division
EHE19_RS08200	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EHE19_RS08210	COG1191	sigma factor activity
EHE19_RS08215	COG1191	sigma factor activity
EHE19_RS08220	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EHE19_RS08225	COG0840	transmembrane signaling receptor activity
EHE19_RS08225	COG3290	protein histidine kinase activity
EHE19_RS08230	COG0606	chelatase, subunit chli
EHE19_RS08235	COG0758	DNA mediated transformation
EHE19_RS08240	COG3621	Patatin-like phospholipase
EHE19_RS08245	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EHE19_RS08250	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EHE19_RS08255	COG1815	bacterial-type flagellum-dependent cell motility
EHE19_RS08260	COG1558	bacterial-type flagellum-dependent cell motility
EHE19_RS08265	COG1677	Flagellar hook-basal body complex protein FliE
EHE19_RS08275	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EHE19_RS08280	COG1317	bacterial-type flagellum organization
EHE19_RS08285	COG1157	protein secretion by the type III secretion system
EHE19_RS08305	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EHE19_RS08320	COG1582	Flagellar protein (FlbD)
EHE19_RS08330	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EHE19_RS08335	COG1776	CheC inhibitor of MCP methylation
EHE19_RS08335	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EHE19_RS08340	COG2201	protein-glutamate methylesterase activity
EHE19_RS08350	COG1338	Plays a role in the flagellum-specific transport system
EHE19_RS08355	COG1987	bacterial-type flagellum assembly
EHE19_RS08360	COG1684	flagellar biosynthetic protein fliR
EHE19_RS08365	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EHE19_RS08370	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EHE19_RS08375	COG1419	protein localization to endoplasmic reticulum
EHE19_RS08385	COG2201	protein-glutamate methylesterase activity
EHE19_RS08390	COG0643	Histidine kinase
EHE19_RS08390	COG2198	Histidine kinase
EHE19_RS08395	COG0835	chemotaxis
EHE19_RS08400	COG1776	CheC inhibitor of MCP methylation
EHE19_RS08405	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
EHE19_RS08415	COG1191	sigma factor activity
EHE19_RS08445	COG3402	PFAM membrane-flanked domain
EHE19_RS08480	COG0492	ferredoxin-NADP+ reductase activity
EHE19_RS08500	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EHE19_RS08510	COG3507	Belongs to the glycosyl hydrolase 43 family
EHE19_RS08545	COG0534	Mate efflux family protein
EHE19_RS08550	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EHE19_RS08555	COG0268	Binds directly to 16S ribosomal RNA
EHE19_RS08575	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EHE19_RS08580	COG1846	Transcriptional regulator
EHE19_RS08585	COG0372	Belongs to the citrate synthase family
EHE19_RS08590	COG2033	superoxide reductase activity
EHE19_RS08595	COG1773	rubredoxin
EHE19_RS08595	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EHE19_RS08600	COG2703	oxygen carrier activity
EHE19_RS08605	COG4209	transmembrane transport
EHE19_RS08610	COG0395	ABC-type sugar transport system, permease component
EHE19_RS08635	COG4753	response regulator
EHE19_RS08635	COG2207	Transcriptional regulator
EHE19_RS08640	COG0745	RESPONSE REGULATOR receiver
EHE19_RS08640	COG2972	Histidine kinase
EHE19_RS08645	COG1501	Belongs to the glycosyl hydrolase 31 family
EHE19_RS08650	COG1472	Belongs to the glycosyl hydrolase 3 family
EHE19_RS08715	COG1131	(ABC) transporter
EHE19_RS08740	COG0564	pseudouridine synthase activity
EHE19_RS08745	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EHE19_RS08755	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EHE19_RS08760	COG1799	cell septum assembly
EHE19_RS08770	COG2302	S4 RNA-binding domain
EHE19_RS08775	COG3599	regulation of cell shape
EHE19_RS08800	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EHE19_RS08805	COG1418	mRNA catabolic process
EHE19_RS08810	COG1692	metallophosphoesterase
EHE19_RS08815	COG1496	oxidoreductase activity
EHE19_RS08825	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EHE19_RS08830	COG0564	pseudouridine synthase activity
EHE19_RS08835	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EHE19_RS08840	COG0540	Belongs to the ATCase OTCase family
EHE19_RS08845	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EHE19_RS08850	COG0284	orotidine-5'-phosphate decarboxylase activity
EHE19_RS08860	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EHE19_RS08865	COG0543	2 iron, 2 sulfur cluster binding
EHE19_RS08870	COG0167	dihydroorotate dehydrogenase activity
EHE19_RS08890	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EHE19_RS08900	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EHE19_RS08935	COG1592	Rubrerythrin
EHE19_RS08940	COG0671	phosphoesterase, PA-phosphatase related
EHE19_RS08975	COG0457	Tetratricopeptide repeat
EHE19_RS08975	COG0705	Rhomboid family
EHE19_RS08980	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EHE19_RS08985	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EHE19_RS08990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EHE19_RS09005	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EHE19_RS09010	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EHE19_RS09020	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EHE19_RS09040	COG2755	lipolytic protein G-D-S-L family
EHE19_RS09040	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EHE19_RS09050	COG0297	glycogen (starch) synthase activity
EHE19_RS09065	COG2972	Histidine kinase
EHE19_RS09070	COG2207	Transcriptional regulator
EHE19_RS09070	COG4753	response regulator
EHE19_RS09075	COG1653	transport
EHE19_RS09080	COG3507	Belongs to the glycosyl hydrolase 43 family
EHE19_RS09080	COG2382	esterase
EHE19_RS09080	COG3693	PFAM glycoside hydrolase, family 10
EHE19_RS09095	COG4221	oxidoreductase activity
EHE19_RS09105	COG1979	alcohol dehydrogenase
EHE19_RS09130	COG1122	ATPase activity
EHE19_RS09135	COG1122	ATPase activity
EHE19_RS09140	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EHE19_RS09155	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EHE19_RS09160	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
EHE19_RS09175	COG1420	regulation of RNA biosynthetic process
EHE19_RS09180	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EHE19_RS09185	COG0443	Heat shock 70 kDa protein
EHE19_RS09190	COG0484	heat shock protein binding
EHE19_RS09195	COG2264	protein methyltransferase activity
EHE19_RS09200	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EHE19_RS09205	COG2201	protein-glutamate methylesterase activity
EHE19_RS09210	COG1561	YicC-like family, N-terminal region
EHE19_RS09215	COG2052	Domain of unknown function (DUF370)
EHE19_RS09220	COG0194	GDP metabolic process
EHE19_RS09225	COG1758	RNA polymerase activity
EHE19_RS09230	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EHE19_RS09230	COG0574	Belongs to the PEP-utilizing enzyme family
EHE19_RS09235	COG3300	MHYT domain
EHE19_RS09235	COG5001	Diguanylate cyclase
EHE19_RS09255	COG0517	IMP dehydrogenase activity
EHE19_RS09275	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EHE19_RS09280	COG1074	ATP-dependent DNA helicase activity
EHE19_RS09295	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EHE19_RS09300	COG1323	Belongs to the UPF0348 family
EHE19_RS09310	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EHE19_RS09325	COG1132	(ABC) transporter
EHE19_RS09330	COG1132	(ABC) transporter
EHE19_RS09355	COG1363	Peptidase, m42
EHE19_RS09375	COG2188	Transcriptional regulator
EHE19_RS09385	COG0586	Pfam SNARE associated Golgi protein
EHE19_RS09395	COG1129	ABC transporter
EHE19_RS09400	COG1172	Belongs to the binding-protein-dependent transport system permease family
EHE19_RS09410	COG1063	alcohol dehydrogenase
EHE19_RS09420	COG0561	phosphatase activity
EHE19_RS09465	COG0535	radical SAM domain protein
EHE19_RS09465	COG1433	Dinitrogenase iron-molybdenum cofactor
EHE19_RS09475	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
EHE19_RS09485	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
EHE19_RS09490	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
EHE19_RS09505	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EHE19_RS09525	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
EHE19_RS09550	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EHE19_RS09550	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EHE19_RS09555	COG1393	Belongs to the ArsC family
EHE19_RS09565	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EHE19_RS09570	COG0626	cystathionine gamma-synthase activity
EHE19_RS09575	COG1959	2 iron, 2 sulfur cluster binding
EHE19_RS09585	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EHE19_RS09585	COG0551	DNA topoisomerase type I activity
EHE19_RS09600	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EHE19_RS09605	COG4676	Protein conserved in bacteria
EHE19_RS09610	COG0617	tRNA 3'-terminal CCA addition
EHE19_RS09645	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EHE19_RS09650	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EHE19_RS09655	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EHE19_RS09660	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
EHE19_RS09665	COG0436	Aminotransferase
EHE19_RS09680	COG0674	pyruvate-flavodoxin oxidoreductase activity
EHE19_RS09685	COG1013	pyruvate-flavodoxin oxidoreductase activity
EHE19_RS09695	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EHE19_RS09700	COG2011	ABC-type metal ion transport system permease component
EHE19_RS09715	COG2217	Heavy metal translocating P-type atpase
EHE19_RS09730	COG5002	protein histidine kinase activity
EHE19_RS09740	COG4124	Belongs to the glycosyl hydrolase 26 family
EHE19_RS09745	COG0662	Cupin 2, conserved barrel domain protein
EHE19_RS09765	COG2918	glutathione biosynthetic process
EHE19_RS09775	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EHE19_RS09780	COG2188	Transcriptional regulator
EHE19_RS09785	COG1940	carbohydrate kinase activity
EHE19_RS09800	COG0165	Argininosuccinate lyase
EHE19_RS09805	COG1940	carbohydrate kinase activity
EHE19_RS09820	COG0395	ABC-type sugar transport system, permease component
EHE19_RS09825	COG1175	transmembrane transport
EHE19_RS09830	COG1653	transport
EHE19_RS09855	COG1773	rubredoxin
EHE19_RS09860	COG0840	transmembrane signaling receptor activity
EHE19_RS09870	COG3940	Belongs to the glycosyl hydrolase 43 family
EHE19_RS09880	COG3507	Belongs to the glycosyl hydrolase 43 family
EHE19_RS09885	COG1609	Transcriptional regulator
EHE19_RS09895	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EHE19_RS09900	COG1648	precorrin-2 dehydrogenase activity
EHE19_RS09900	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EHE19_RS09905	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EHE19_RS09915	COG2895	sulfate adenylyltransferase (ATP) activity
EHE19_RS09920	COG0175	sulfate reduction
EHE19_RS09925	COG0175	sulfate reduction
EHE19_RS09940	COG4208	sulfate ABC transporter
EHE19_RS09950	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EHE19_RS09975	COG4974	Belongs to the 'phage' integrase family
EHE19_RS09980	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EHE19_RS09995	COG2720	vancomycin resistance protein
EHE19_RS10005	COG0301	tRNA thio-modification
EHE19_RS10010	COG1104	cysteine desulfurase activity
EHE19_RS10020	COG3260	NADH ubiquinone oxidoreductase 20
EHE19_RS10025	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
EHE19_RS10025	COG3261	NADH dehydrogenase
EHE19_RS10030	COG0651	ATP synthesis coupled electron transport
EHE19_RS10045	COG0651	ATP synthesis coupled electron transport
EHE19_RS10050	COG1388	LysM domain
EHE19_RS10055	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EHE19_RS10060	COG1923	regulation of RNA biosynthetic process
EHE19_RS10065	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EHE19_RS10075	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EHE19_RS10085	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EHE19_RS10105	COG0740	serine-type endopeptidase activity
EHE19_RS10110	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EHE19_RS10120	COG0612	Peptidase, M16
EHE19_RS10125	COG1185	polyribonucleotide nucleotidyltransferase activity
EHE19_RS10130	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EHE19_RS10135	COG0714	Associated with various cellular activities
EHE19_RS10145	COG1305	Transglutaminase-like
EHE19_RS10150	COG2203	Gaf domain
EHE19_RS10150	COG4251	negative regulation of phosphorylation
EHE19_RS10150	COG3706	GGDEF domain
EHE19_RS10150	COG5001	Diguanylate cyclase
EHE19_RS10160	COG1316	TRANSCRIPTIONal
EHE19_RS10165	COG0488	(ABC) transporter
EHE19_RS10180	COG2848	UPF0210 protein
EHE19_RS10185	COG3830	Belongs to the UPF0237 family
EHE19_RS10200	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EHE19_RS10210	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EHE19_RS10215	COG0539	negative regulation of cytoplasmic translation
EHE19_RS10215	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EHE19_RS10220	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EHE19_RS10245	COG2081	HI0933 family
EHE19_RS10265	COG0511	ligase activity, forming carbon-carbon bonds
EHE19_RS10270	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EHE19_RS10280	COG1187	pseudouridine synthase activity
EHE19_RS10285	COG3874	Sporulation protein YtfJ
EHE19_RS10295	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EHE19_RS10305	COG1994	Peptidase M50
EHE19_RS10310	COG1686	Belongs to the peptidase S11 family
EHE19_RS10315	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EHE19_RS10320	COG4974	Belongs to the 'phage' integrase family
EHE19_RS10325	COG1300	Membrane
EHE19_RS10335	COG0328	RNA-DNA hybrid ribonuclease activity
EHE19_RS10340	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EHE19_RS10355	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EHE19_RS10365	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EHE19_RS10400	COG0792	nuclease activity
EHE19_RS10405	COG2257	FlhB HrpN YscU SpaS Family
EHE19_RS10415	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EHE19_RS10440	COG0335	large ribosomal subunit rRNA binding
EHE19_RS10445	COG0336	Belongs to the RNA methyltransferase TrmD family
EHE19_RS10450	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EHE19_RS10460	COG0228	four-way junction DNA binding
EHE19_RS10465	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EHE19_RS10470	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EHE19_RS10495	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EHE19_RS10510	COG4443	Transcriptional Coactivator p15 (PC4)
EHE19_RS10515	COG1615	UPF0182 protein
EHE19_RS10520	COG0552	protein localization to endoplasmic reticulum
EHE19_RS10525	COG1196	nuclear chromosome segregation
EHE19_RS10545	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EHE19_RS10555	COG2359	stage V sporulation protein S
EHE19_RS10565	COG0571	ribonuclease III activity
EHE19_RS10570	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EHE19_RS10575	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EHE19_RS10580	COG1028	Short-chain dehydrogenase reductase Sdr
EHE19_RS10585	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EHE19_RS10590	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EHE19_RS10595	COG0416	fatty acid biosynthetic process
EHE19_RS10605	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EHE19_RS10610	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EHE19_RS10615	COG2137	regulation of response to DNA damage stimulus
EHE19_RS10620	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EHE19_RS10625	COG0728	peptidoglycan biosynthetic process
EHE19_RS10630	COG1058	Belongs to the CinA family
EHE19_RS10630	COG1546	Belongs to the CinA family
EHE19_RS10640	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
EHE19_RS10655	COG0318	PFAM AMP-dependent synthetase and ligase
EHE19_RS10680	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EHE19_RS10685	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EHE19_RS10690	COG0210	DNA helicase
EHE19_RS10700	COG1199	ATP-dependent helicase activity
EHE19_RS10700	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EHE19_RS10715	COG0456	acetyltransferase
EHE19_RS10720	COG1408	metallophosphoesterase
EHE19_RS10730	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EHE19_RS10745	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EHE19_RS10800	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EHE19_RS10805	COG0358	DNA primase activity
EHE19_RS10820	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EHE19_RS10825	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EHE19_RS10850	COG1862	Preprotein translocase
EHE19_RS10855	COG0343	queuine tRNA-ribosyltransferase activity
EHE19_RS10860	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EHE19_RS10865	COG0527	aspartate kinase activity
EHE19_RS10870	COG2247	cell wall binding repeat
EHE19_RS10870	COG2385	sporulation resulting in formation of a cellular spore
EHE19_RS10875	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EHE19_RS10880	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EHE19_RS10885	COG0527	aspartate kinase activity
EHE19_RS10925	COG0840	transmembrane signaling receptor activity
EHE19_RS10935	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EHE19_RS10945	COG2996	Protein conserved in bacteria
EHE19_RS10950	COG2223	nitrite transmembrane transporter activity
EHE19_RS10955	COG0673	inositol 2-dehydrogenase activity
EHE19_RS10985	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EHE19_RS10995	COG2135	peptidase activity
EHE19_RS11005	COG0514	ATP-dependent DNA helicase (RecQ)
EHE19_RS11010	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EHE19_RS11015	COG1028	Short-chain dehydrogenase reductase Sdr
EHE19_RS11030	COG1132	(ABC) transporter
EHE19_RS11050	COG5520	Belongs to the glycosyl hydrolase 30 family
EHE19_RS11055	COG4733	cellulase activity
EHE19_RS11075	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EHE19_RS11100	COG4733	cellulase activity
EHE19_RS11105	COG3401	FG-GAP repeat protein
EHE19_RS11105	COG2755	lipolytic protein G-D-S-L family
EHE19_RS11110	COG3401	FG-GAP repeat protein
EHE19_RS11135	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EHE19_RS11140	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EHE19_RS11145	COG3314	Sporulation integral membrane protein YlbJ
EHE19_RS11155	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EHE19_RS11160	COG0742	ribosomal rna small subunit methyltransferase
EHE19_RS11165	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EHE19_RS11170	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EHE19_RS11180	COG3706	GGDEF domain
EHE19_RS11180	COG2203	Gaf domain
EHE19_RS11180	COG5001	Diguanylate cyclase
EHE19_RS11180	COG4251	negative regulation of phosphorylation
EHE19_RS11190	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EHE19_RS11195	COG0297	glycogen (starch) synthase activity
EHE19_RS11200	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
EHE19_RS11200	COG2199	diguanylate cyclase activity
EHE19_RS11205	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EHE19_RS11210	COG5002	protein histidine kinase activity
EHE19_RS11215	COG0745	RESPONSE REGULATOR receiver
EHE19_RS11220	COG0745	RESPONSE REGULATOR receiver
EHE19_RS11225	COG0750	zinc metalloprotease
EHE19_RS11230	COG0497	DNA recombination
EHE19_RS11235	COG1438	arginine binding
EHE19_RS11240	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EHE19_RS11245	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EHE19_RS11250	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EHE19_RS11265	COG1722	exodeoxyribonuclease VII activity
EHE19_RS11270	COG1570	exodeoxyribonuclease VII activity
EHE19_RS11275	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EHE19_RS11290	COG1302	Protein conserved in bacteria
EHE19_RS11330	COG3854	ATPases associated with a variety of cellular activities
EHE19_RS11385	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EHE19_RS11390	COG0006	proline dipeptidase activity
EHE19_RS11395	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EHE19_RS11405	COG1362	aminopeptidase activity
EHE19_RS11410	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EHE19_RS11420	COG0482	sulfurtransferase activity
EHE19_RS11425	COG0822	iron-sulfur transferase activity
EHE19_RS11435	COG1959	2 iron, 2 sulfur cluster binding
EHE19_RS11450	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EHE19_RS11455	COG0840	transmembrane signaling receptor activity
EHE19_RS11485	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EHE19_RS11490	COG1518	maintenance of DNA repeat elements
EHE19_RS11550	COG4213	ABC transporter substrate-binding protein
EHE19_RS11555	COG4753	response regulator
EHE19_RS11555	COG2207	Transcriptional regulator
EHE19_RS11560	COG2972	Histidine kinase
EHE19_RS11570	COG0481	GTPase activity
EHE19_RS11585	COG1929	Belongs to the glycerate kinase type-1 family
EHE19_RS11595	COG2205	protein histidine kinase activity
EHE19_RS11605	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EHE19_RS11615	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EHE19_RS11620	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EHE19_RS11625	COG1490	D-aminoacyl-tRNA deacylase activity
EHE19_RS11630	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EHE19_RS11635	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EHE19_RS11640	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EHE19_RS11640	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EHE19_RS11645	COG1466	dna polymerase III delta subunit
EHE19_RS11655	COG0791	NLP P60 protein
EHE19_RS11675	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
EHE19_RS11680	COG2873	o-acetylhomoserine
EHE19_RS11685	COG1522	sequence-specific DNA binding
EHE19_RS11690	COG1293	RNA-binding protein homologous to eukaryotic snRNP
EHE19_RS11695	COG0436	Aminotransferase
EHE19_RS11700	COG1132	(ABC) transporter
EHE19_RS11705	COG1132	(ABC) transporter
EHE19_RS11730	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EHE19_RS11735	COG1162	GTPase activity
EHE19_RS11740	COG0515	serine threonine protein kinase
EHE19_RS11740	COG2815	serine threonine protein kinase
EHE19_RS11750	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EHE19_RS11755	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EHE19_RS11755	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EHE19_RS11760	COG2738	Putative neutral zinc metallopeptidase
EHE19_RS11770	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EHE19_RS11775	COG0242	peptide deformylase activity
EHE19_RS11780	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EHE19_RS11790	COG2272	Belongs to the type-B carboxylesterase lipase family
EHE19_RS11895	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EHE19_RS11905	COG1408	metallophosphoesterase
EHE19_RS11910	COG3507	Belongs to the glycosyl hydrolase 43 family
EHE19_RS11950	COG0745	RESPONSE REGULATOR receiver
EHE19_RS11955	COG0024	Methionine aminopeptidase
EHE19_RS12000	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EHE19_RS12030	COG0012	GTP binding
EHE19_RS12035	COG0835	chemotaxis
EHE19_RS12055	COG1132	(ABC) transporter
EHE19_RS12060	COG1132	(ABC) transporter
EHE19_RS12075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EHE19_RS12080	COG1381	Involved in DNA repair and RecF pathway recombination
EHE19_RS12090	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EHE19_RS12095	COG0295	cytidine deaminase activity
EHE19_RS12100	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EHE19_RS12105	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EHE19_RS12110	COG1480	7TM receptor with intracellular HD hydrolase
EHE19_RS12115	COG1702	phosphate starvation-inducible protein PhoH
EHE19_RS12170	COG0697	spore germination
EHE19_RS12175	COG1686	Belongs to the peptidase S11 family
EHE19_RS12180	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EHE19_RS12185	COG3583	domain protein
EHE19_RS12185	COG3584	3D domain protein
EHE19_RS12205	COG0432	Pfam Uncharacterised protein family UPF0047
EHE19_RS12215	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
EHE19_RS12220	COG2873	o-acetylhomoserine
EHE19_RS12225	COG0583	DNA-binding transcription factor activity
EHE19_RS12305	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EHE19_RS12310	COG0583	DNA-binding transcription factor activity
EHE19_RS12320	COG0840	transmembrane signaling receptor activity
EHE19_RS12330	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EHE19_RS12335	COG0326	Molecular chaperone. Has ATPase activity
EHE19_RS12340	COG2719	SpoVR family
EHE19_RS12345	COG2718	Belongs to the UPF0229 family
EHE19_RS12350	COG2766	serine protein kinase
EHE19_RS12365	COG1686	Belongs to the peptidase S11 family
EHE19_RS12390	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EHE19_RS12395	COG0772	Belongs to the SEDS family
EHE19_RS12400	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EHE19_RS12405	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EHE19_RS12410	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EHE19_RS12415	COG0768	penicillin binding
EHE19_RS12425	COG0275	rRNA processing
EHE19_RS12430	COG2001	Belongs to the MraZ family
EHE19_RS12435	COG0772	Belongs to the SEDS family
EHE19_RS12440	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EHE19_RS12445	COG0612	Peptidase, M16
EHE19_RS12450	COG0612	Peptidase, M16
EHE19_RS12460	COG0577	efflux transmembrane transporter activity
EHE19_RS12475	COG1136	(ABC) transporter
EHE19_RS12480	COG0309	Hydrogenase expression formation protein (HypE)
EHE19_RS12485	COG0409	Hydrogenase expression formation protein
EHE19_RS12490	COG0298	carbon dioxide binding
EHE19_RS12500	COG0196	riboflavin kinase activity
EHE19_RS12505	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EHE19_RS12510	COG2404	hydrolase activity, acting on ester bonds
EHE19_RS12515	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EHE19_RS12520	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EHE19_RS12530	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EHE19_RS12535	COG0195	Participates in both transcription termination and antitermination
EHE19_RS12540	COG0779	Required for maturation of 30S ribosomal subunits
EHE19_RS12545	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EHE19_RS12550	COG0750	zinc metalloprotease
EHE19_RS12555	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EHE19_RS12560	COG4589	Belongs to the CDS family
EHE19_RS12575	COG0233	cytoplasmic translational termination
EHE19_RS12580	COG0528	UMP kinase activity
EHE19_RS12585	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EHE19_RS12590	COG0052	Belongs to the universal ribosomal protein uS2 family
EHE19_RS12605	COG2217	Heavy metal translocating P-type atpase
EHE19_RS12610	COG4733	cellulase activity
EHE19_RS12635	COG2267	carboxylic ester hydrolase activity
EHE19_RS12645	COG3773	Cell wall hydrolase
EHE19_RS12645	COG3409	Peptidoglycan-binding domain 1 protein
EHE19_RS12655	COG0778	Nitroreductase
EHE19_RS12685	COG3546	catalase activity
EHE19_RS12725	COG3546	catalase activity
EHE19_RS12730	COG2002	toxin-antitoxin pair type II binding
EHE19_RS12745	COG0840	transmembrane signaling receptor activity
EHE19_RS12760	COG1175	transmembrane transport
EHE19_RS12765	COG1653	transport
EHE19_RS12770	COG3279	Response regulator of the LytR AlgR family
EHE19_RS12775	COG2972	Histidine kinase
EHE19_RS12790	COG1396	sequence-specific DNA binding
EHE19_RS12810	COG3546	catalase activity
EHE19_RS12825	COG2002	toxin-antitoxin pair type II binding
EHE19_RS12835	COG5001	Diguanylate cyclase
EHE19_RS12835	COG3300	MHYT domain
EHE19_RS12855	COG3291	Pkd domain containing protein
EHE19_RS12865	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EHE19_RS13000	COG1222	aaa ATPase
EHE19_RS13055	COG5444	nuclease activity
EHE19_RS13060	COG5297	Belongs to the glycosyl hydrolase family 6
EHE19_RS13060	COG4447	cellulose binding
EHE19_RS13080	COG0768	penicillin binding
EHE19_RS13095	COG0248	Ppx GppA phosphatase
EHE19_RS13110	COG0456	acetyltransferase
EHE19_RS13115	COG0826	peptidase U32
EHE19_RS13120	COG4122	O-methyltransferase activity
EHE19_RS13125	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EHE19_RS13130	COG1217	gtp-binding protein TYPA
EHE19_RS13135	COG1193	negative regulation of DNA recombination
EHE19_RS13140	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EHE19_RS13155	COG0484	heat shock protein binding
EHE19_RS13165	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EHE19_RS13170	COG0824	Thioesterase
EHE19_RS13200	COG0423	glycine-tRNA ligase activity
EHE19_RS13205	COG3693	PFAM glycoside hydrolase, family 10
EHE19_RS13205	COG3507	Belongs to the glycosyl hydrolase 43 family
EHE19_RS13205	COG2382	esterase
EHE19_RS13210	COG2382	esterase
EHE19_RS13210	COG3693	PFAM glycoside hydrolase, family 10
EHE19_RS13210	COG3507	Belongs to the glycosyl hydrolase 43 family
EHE19_RS13215	COG3507	Belongs to the glycosyl hydrolase 43 family
EHE19_RS13220	COG0653	protein targeting
EHE19_RS13230	COG4496	protein, YerC YecD
EHE19_RS13240	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EHE19_RS13245	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EHE19_RS13250	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EHE19_RS13255	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EHE19_RS13260	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EHE19_RS13270	COG0463	Glycosyl transferase, family 2
EHE19_RS13275	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EHE19_RS13285	COG1596	polysaccharide export
EHE19_RS13285	COG1555	photosystem II stabilization
EHE19_RS13290	COG1686	Belongs to the peptidase S11 family
EHE19_RS13295	COG0318	PFAM AMP-dependent synthetase and ligase
EHE19_RS13300	COG0488	(ABC) transporter
EHE19_RS13305	COG0799	negative regulation of ribosome biogenesis
EHE19_RS13315	COG1713	HD superfamily hydrolase involved in NAD metabolism
EHE19_RS13320	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EHE19_RS13325	COG0151	Belongs to the GarS family
EHE19_RS13330	COG0138	bifunctional purine biosynthesis protein purh
EHE19_RS13340	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EHE19_RS13345	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EHE19_RS13350	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EHE19_RS13375	COG3706	GGDEF domain
EHE19_RS13390	COG0456	acetyltransferase
EHE19_RS13395	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EHE19_RS13400	COG0346	lactoylglutathione lyase activity
EHE19_RS13470	COG0464	growth
EHE19_RS13550	COG4974	Belongs to the 'phage' integrase family
EHE19_RS13555	COG0519	Catalyzes the synthesis of GMP from XMP
EHE19_RS13560	COG1242	4 iron, 4 sulfur cluster binding
EHE19_RS13565	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
EHE19_RS13570	COG1691	(AIR) carboxylase
EHE19_RS13580	COG0561	phosphatase activity
EHE19_RS13585	COG0436	Aminotransferase
EHE19_RS13590	COG1522	sequence-specific DNA binding
EHE19_RS13615	COG3118	belongs to the thioredoxin family
EHE19_RS13625	COG5434	Belongs to the glycosyl hydrolase 28 family
EHE19_RS13625	COG4632	Exopolysaccharide biosynthesis protein
EHE19_RS13660	COG1649	PFAM Uncharacterised BCR, COG1649
EHE19_RS13690	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EHE19_RS13690	COG0551	DNA topoisomerase type I activity
EHE19_RS13740	COG1482	cell wall glycoprotein biosynthetic process
EHE19_RS13775	COG0586	Pfam SNARE associated Golgi protein
EHE19_RS13790	COG1013	pyruvate-flavodoxin oxidoreductase activity
EHE19_RS13790	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EHE19_RS13790	COG0674	pyruvate-flavodoxin oxidoreductase activity
EHE19_RS13790	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EHE19_RS13820	COG0674	pyruvate-flavodoxin oxidoreductase activity
EHE19_RS13820	COG1013	pyruvate-flavodoxin oxidoreductase activity
EHE19_RS13820	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EHE19_RS13820	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EHE19_RS13825	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EHE19_RS13860	COG0803	Belongs to the bacterial solute-binding protein 9 family
EHE19_RS13870	COG5002	protein histidine kinase activity
EHE19_RS13880	COG0577	efflux transmembrane transporter activity
EHE19_RS13885	COG1136	(ABC) transporter
EHE19_RS13890	COG0697	spore germination
EHE19_RS13905	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EHE19_RS13910	COG0598	Magnesium transport protein CorA
EHE19_RS13925	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EHE19_RS13930	COG1968	undecaprenyl-diphosphatase activity
EHE19_RS13945	COG1028	Short-chain dehydrogenase reductase Sdr
EHE19_RS13965	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EHE19_RS13970	COG2207	Transcriptional regulator
EHE19_RS13970	COG4753	response regulator
EHE19_RS13975	COG2972	Histidine kinase
EHE19_RS13980	COG1653	transport
EHE19_RS14010	COG1166	arginine decarboxylase activity
EHE19_RS14050	COG0142	geranyltranstransferase activity
EHE19_RS14055	COG1252	NADH dehydrogenase
EHE19_RS14105	COG0318	PFAM AMP-dependent synthetase and ligase
EHE19_RS14120	COG0513	Belongs to the DEAD box helicase family
EHE19_RS14130	COG1136	(ABC) transporter
EHE19_RS14130	COG0577	efflux transmembrane transporter activity
EHE19_RS14135	COG0563	adenylate kinase activity
EHE19_RS14165	COG0500	methyltransferase
EHE19_RS14165	COG3615	Tellurite resistance protein tehB
EHE19_RS14195	COG0222	ribosome binding
EHE19_RS14220	COG1131	(ABC) transporter
EHE19_RS14370	COG4677	pectinesterase activity
EHE19_RS14380	COG4447	cellulose binding
EHE19_RS14380	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EHE19_RS14385	COG4124	Belongs to the glycosyl hydrolase 26 family
EHE19_RS14395	COG4733	cellulase activity
EHE19_RS14400	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EHE19_RS14410	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EHE19_RS14420	COG1528	Iron-storage protein
EHE19_RS14425	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EHE19_RS14440	COG1131	(ABC) transporter
EHE19_RS14450	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EHE19_RS14515	COG0442	prolyl-tRNA aminoacylation
EHE19_RS14530	COG1115	amino acid carrier protein
EHE19_RS14535	COG1489	DNA binding
EHE19_RS14550	COG0017	Asparaginyl-tRNA synthetase
EHE19_RS14555	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EHE19_RS14560	COG0038	chloride channel
EHE19_RS14595	COG1088	dTDP-glucose 4,6-dehydratase activity
EHE19_RS14615	COG0840	transmembrane signaling receptor activity
EHE19_RS14620	COG5002	protein histidine kinase activity
EHE19_RS14625	COG0745	RESPONSE REGULATOR receiver
EHE19_RS14650	COG1138	Cytochrome C-type biogenesis protein
EHE19_RS14670	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EHE19_RS14675	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
EHE19_RS14680	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EHE19_RS14685	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EHE19_RS14685	COG0512	Glutamine amidotransferase of anthranilate synthase
EHE19_RS14715	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EHE19_RS14735	COG2207	Transcriptional regulator
EHE19_RS14735	COG4753	response regulator
EHE19_RS14740	COG3275	phosphorelay sensor kinase activity
EHE19_RS14745	COG0784	Response regulator, receiver
EHE19_RS14745	COG0835	chemotaxis
EHE19_RS14750	COG1192	Involved in chromosome partitioning
EHE19_RS14755	COG2198	Histidine kinase
EHE19_RS14755	COG0784	Response regulator, receiver
EHE19_RS14755	COG0643	Histidine kinase
EHE19_RS14760	COG0643	Histidine kinase
EHE19_RS14760	COG0784	Response regulator, receiver
EHE19_RS14760	COG2198	Histidine kinase
EHE19_RS14765	COG0745	RESPONSE REGULATOR receiver
EHE19_RS14770	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EHE19_RS14785	COG0745	RESPONSE REGULATOR receiver
EHE19_RS14790	COG2201	protein-glutamate methylesterase activity
EHE19_RS14795	COG0835	chemotaxis
EHE19_RS14800	COG0840	transmembrane signaling receptor activity
EHE19_RS14805	COG3290	protein histidine kinase activity
EHE19_RS14805	COG0840	transmembrane signaling receptor activity
EHE19_RS14815	COG2201	protein-glutamate methylesterase activity
EHE19_RS14825	COG3507	Belongs to the glycosyl hydrolase 43 family
EHE19_RS14840	COG1177	transmembrane transport
EHE19_RS14845	COG1176	ABC-type spermidine putrescine transport system, permease component I
EHE19_RS14850	COG3842	ATPase activity
EHE19_RS14855	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EHE19_RS14860	COG0113	porphobilinogen synthase activity
EHE19_RS14885	COG1122	ATPase activity
EHE19_RS14895	COG0310	cobalt ion transport
EHE19_RS14925	COG0009	L-threonylcarbamoyladenylate synthase
EHE19_RS14930	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EHE19_RS14935	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EHE19_RS14970	COG0318	PFAM AMP-dependent synthetase and ligase
EHE19_RS14975	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EHE19_RS14980	COG0737	Belongs to the 5'-nucleotidase family
EHE19_RS14995	COG4555	ABC transporter
EHE19_RS15000	COG2197	response regulator
EHE19_RS15015	COG1028	Short-chain dehydrogenase reductase Sdr
EHE19_RS15050	COG0535	radical SAM domain protein
EHE19_RS15095	COG0457	Tetratricopeptide repeat
EHE19_RS15095	COG0463	Glycosyl transferase, family 2
EHE19_RS15110	COG0577	efflux transmembrane transporter activity
EHE19_RS15120	COG1136	(ABC) transporter
EHE19_RS15125	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EHE19_RS15145	COG3118	belongs to the thioredoxin family
EHE19_RS15150	COG0446	pyridine nucleotide-disulphide oxidoreductase
EHE19_RS15155	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EHE19_RS15170	COG0019	diaminopimelate decarboxylase activity
EHE19_RS15205	COG1395	domain, Protein
EHE19_RS15230	COG1846	Transcriptional regulator
EHE19_RS15230	COG0456	acetyltransferase
EHE19_RS15240	COG0778	Nitroreductase
EHE19_RS15240	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
EHE19_RS15245	COG2226	methyltransferase
EHE19_RS15260	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EHE19_RS15280	COG0159	tryptophan synthase activity
EHE19_RS15285	COG0133	tryptophan synthase activity
EHE19_RS15295	COG0134	indole-3-glycerol-phosphate synthase activity
EHE19_RS15300	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EHE19_RS15315	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EHE19_RS15345	COG0519	Catalyzes the synthesis of GMP from XMP
EHE19_RS15355	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EHE19_RS15365	COG3279	Response regulator of the LytR AlgR family
EHE19_RS15375	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EHE19_RS15380	COG2086	electron transfer activity
EHE19_RS15385	COG0028	Belongs to the TPP enzyme family
EHE19_RS15415	COG0163	prenyltransferase activity
EHE19_RS15430	COG2249	NAD(P)H dehydrogenase (quinone) activity
EHE19_RS15440	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EHE19_RS15450	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EHE19_RS15480	COG3177	Filamentation induced by cAMP protein fic
EHE19_RS15520	COG0798	PFAM Bile acid sodium symporter
EHE19_RS15570	COG4824	toxin secretion phage lysis holin
EHE19_RS15660	COG4695	Portal protein
EHE19_RS15665	COG3708	Transcriptional regulator
EHE19_RS15665	COG2207	Transcriptional regulator
EHE19_RS15670	COG4626	Terminase
EHE19_RS15670	COG1802	Transcriptional regulator
EHE19_RS15720	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EHE19_RS15765	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EHE19_RS15765	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EHE19_RS15895	COG0583	DNA-binding transcription factor activity
EHE19_RS15905	COG2059	Chromate
EHE19_RS15920	COG1131	(ABC) transporter
EHE19_RS15945	COG2894	cell division
EHE19_RS15970	COG0822	iron-sulfur transferase activity
EHE19_RS15975	COG1342	Belongs to the UPF0251 family
EHE19_RS15985	COG3290	protein histidine kinase activity
EHE19_RS16015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHE19_RS16030	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
EHE19_RS16035	COG1492	cobalamin metabolic process
EHE19_RS16050	COG1797	cobyrinic acid a,c-diamide synthase activity
EHE19_RS16065	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EHE19_RS16070	COG0113	porphobilinogen synthase activity
EHE19_RS16080	COG0181	hydroxymethylbilane synthase activity
EHE19_RS16115	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
EHE19_RS16120	COG1122	ATPase activity
EHE19_RS16125	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EHE19_RS16135	COG0310	cobalt ion transport
EHE19_RS16195	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EHE19_RS16285	COG1192	Involved in chromosome partitioning
EHE19_RS16305	COG1132	(ABC) transporter
EHE19_RS16320	COG1131	(ABC) transporter
EHE19_RS16325	COG1404	Belongs to the peptidase S8 family
EHE19_RS16330	COG0535	radical SAM domain protein
EHE19_RS16335	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EHE19_RS16405	COG1136	(ABC) transporter
EHE19_RS16410	COG0577	efflux transmembrane transporter activity
EHE19_RS16415	COG1132	(ABC) transporter
EHE19_RS16445	COG0641	radical SAM
EHE19_RS16515	COG2226	methyltransferase
EHE19_RS16530	COG0577	efflux transmembrane transporter activity
EHE19_RS16530	COG1136	(ABC) transporter
EHE19_RS16535	COG1136	(ABC) transporter
EHE19_RS16535	COG0577	efflux transmembrane transporter activity
EHE19_RS16540	COG1032	radical SAM domain protein
EHE19_RS16550	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EHE19_RS16555	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EHE19_RS16565	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EHE19_RS16610	COG1802	Transcriptional regulator
EHE19_RS16610	COG4626	Terminase
EHE19_RS16635	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EHE19_RS16770	COG4824	toxin secretion phage lysis holin
EHE19_RS17165	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EHE19_RS17195	COG0739	heme binding
EHE19_RS17215	COG0235	Class ii aldolase
EHE19_RS17230	COG1609	Transcriptional regulator
EHE19_RS17260	COG0840	transmembrane signaling receptor activity
EHE19_RS17265	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EHE19_RS17270	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EHE19_RS17275	COG0049	tRNA binding
EHE19_RS17280	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EHE19_RS17285	COG1358	cellular component organization or biogenesis
EHE19_RS17290	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EHE19_RS17295	COG0085	RNA polymerase activity
EHE19_RS17300	COG0222	ribosome binding
EHE19_RS17305	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EHE19_RS17310	COG0081	regulation of translation
EHE19_RS17315	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EHE19_RS17320	COG0250	Participates in transcription elongation, termination and antitermination
EHE19_RS17330	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EHE19_RS17335	COG0028	Belongs to the TPP enzyme family
EHE19_RS17340	COG0129	dihydroxy-acid dehydratase activity
EHE19_RS17355	COG3949	Membrane
EHE19_RS17375	COG1131	(ABC) transporter
EHE19_RS17380	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EHE19_RS17395	COG0504	CTP synthase activity
EHE19_RS17405	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EHE19_RS17430	COG1216	Glycosyl transferase, family 2
EHE19_RS17430	COG1442	glycosyl transferase family 8
EHE19_RS17435	COG0438	transferase activity, transferring glycosyl groups
EHE19_RS17445	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EHE19_RS17455	COG1132	(ABC) transporter
EHE19_RS17490	COG0438	transferase activity, transferring glycosyl groups
EHE19_RS17495	COG0535	radical SAM domain protein
EHE19_RS17530	COG3594	Acyltransferase
EHE19_RS17540	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EHE19_RS17560	COG0793	Belongs to the peptidase S41A family
EHE19_RS17575	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EHE19_RS17580	COG5434	Belongs to the glycosyl hydrolase 28 family
EHE19_RS17585	COG0840	transmembrane signaling receptor activity
EHE19_RS17585	COG3290	protein histidine kinase activity
EHE19_RS17590	COG0018	arginyl-trna synthetase
EHE19_RS17600	COG1181	Belongs to the D-alanine--D-alanine ligase family
EHE19_RS17610	COG2385	sporulation resulting in formation of a cellular spore
EHE19_RS17615	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EHE19_RS17625	COG1361	Conserved repeat domain
EHE19_RS17670	COG3345	alpha-galactosidase
EHE19_RS17675	COG2382	esterase
EHE19_RS17675	COG3507	Belongs to the glycosyl hydrolase 43 family
EHE19_RS17675	COG3693	PFAM glycoside hydrolase, family 10
EHE19_RS17680	COG3507	Belongs to the glycosyl hydrolase 43 family
EHE19_RS17680	COG3693	PFAM glycoside hydrolase, family 10
EHE19_RS17680	COG2382	esterase
EHE19_RS17685	COG2382	esterase
EHE19_RS17685	COG3693	PFAM glycoside hydrolase, family 10
EHE19_RS17685	COG3507	Belongs to the glycosyl hydrolase 43 family
EHE19_RS17695	COG3507	Belongs to the glycosyl hydrolase 43 family
EHE19_RS17700	COG5520	Belongs to the glycosyl hydrolase 30 family
EHE19_RS17705	COG3345	alpha-galactosidase
EHE19_RS17720	COG3693	PFAM glycoside hydrolase, family 10
EHE19_RS17725	COG3507	Belongs to the glycosyl hydrolase 43 family
EHE19_RS17725	COG3693	PFAM glycoside hydrolase, family 10
EHE19_RS17725	COG2382	esterase
EHE19_RS17730	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EHE19_RS17735	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EHE19_RS17740	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EHE19_RS17745	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EHE19_RS17750	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EHE19_RS17755	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EHE19_RS17760	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EHE19_RS17765	COG0356	it plays a direct role in the translocation of protons across the membrane
EHE19_RS17785	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EHE19_RS17790	COG2131	deaminase
EHE19_RS17795	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EHE19_RS17800	COG0698	ribose 5-phosphate isomerase
EHE19_RS17805	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EHE19_RS17810	COG0009	L-threonylcarbamoyladenylate synthase
EHE19_RS17815	COG0428	transporter
EHE19_RS17820	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EHE19_RS17835	COG1253	flavin adenine dinucleotide binding
EHE19_RS17860	COG1193	negative regulation of DNA recombination
EHE19_RS17875	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EHE19_RS17880	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EHE19_RS17885	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EHE19_RS17900	COG0640	Transcriptional regulator
EHE19_RS17905	COG1472	Belongs to the glycosyl hydrolase 3 family
EHE19_RS17910	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EHE19_RS17925	COG1216	Glycosyl transferase, family 2
EHE19_RS17940	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EHE19_RS17950	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EHE19_RS17960	COG0737	Belongs to the 5'-nucleotidase family
EHE19_RS17975	COG4555	ABC transporter
EHE19_RS17980	COG2197	response regulator
EHE19_RS17990	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
EHE19_RS18020	COG4974	Belongs to the 'phage' integrase family
EHE19_RS18055	COG0582	viral genome integration into host DNA
EHE19_RS18215	COG2814	Major facilitator Superfamily
EHE19_RS18245	COG1705	Flagellar rod assembly protein muramidase FlgJ
EHE19_RS18245	COG1388	LysM domain
EHE19_RS18270	COG3848	Pyruvate phosphate dikinase
EHE19_RS18270	COG0574	Belongs to the PEP-utilizing enzyme family
EHE19_RS18290	COG1132	(ABC) transporter
EHE19_RS18310	COG0668	transmembrane transport
EHE19_RS18315	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EHE19_RS18320	COG1773	rubredoxin
EHE19_RS18340	COG0024	Methionine aminopeptidase
EHE19_RS18350	COG0375	protein maturation
EHE19_RS18360	COG0649	NAD binding
EHE19_RS18370	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EHE19_RS18380	COG2111	Na H antiporter
EHE19_RS18380	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EHE19_RS18385	COG0628	permease
EHE19_RS18390	COG2890	protein-(glutamine-N5) methyltransferase activity
EHE19_RS18395	COG3872	metal-dependent enzyme
EHE19_RS18400	COG0254	rRNA binding
EHE19_RS18405	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EHE19_RS18425	COG0813	purine-nucleoside phosphorylase activity
EHE19_RS18430	COG1368	sulfuric ester hydrolase activity
EHE19_RS18435	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EHE19_RS18440	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EHE19_RS18445	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EHE19_RS18465	COG5002	protein histidine kinase activity
EHE19_RS18470	COG0745	RESPONSE REGULATOR receiver
EHE19_RS18490	COG0673	inositol 2-dehydrogenase activity
EHE19_RS18525	COG0110	maltose O-acetyltransferase activity
EHE19_RS18535	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EHE19_RS18600	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EHE19_RS18610	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EHE19_RS18625	COG0037	tRNA processing
EHE19_RS18630	COG5434	Belongs to the glycosyl hydrolase 28 family
EHE19_RS18630	COG4632	Exopolysaccharide biosynthesis protein
EHE19_RS18635	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EHE19_RS18650	COG1472	Belongs to the glycosyl hydrolase 3 family
EHE19_RS18655	COG3458	cephalosporin-C deacetylase activity
EHE19_RS18660	COG0840	transmembrane signaling receptor activity
EHE19_RS18665	COG3459	Glycosyltransferase 36 associated
EHE19_RS18670	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EHE19_RS18675	COG1121	(ABC) transporter
EHE19_RS18680	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EHE19_RS18690	COG3655	Transcriptional regulator
EHE19_RS18710	COG3973	AAA domain
EHE19_RS18735	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EHE19_RS18760	COG2115	Belongs to the xylose isomerase family
EHE19_RS18765	COG1940	carbohydrate kinase activity
EHE19_RS18770	COG1070	Carbohydrate kinase
EHE19_RS18775	COG0840	transmembrane signaling receptor activity
EHE19_RS18785	COG0443	Heat shock 70 kDa protein
EHE19_RS18790	COG0745	RESPONSE REGULATOR receiver
EHE19_RS18805	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EHE19_RS18810	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EHE19_RS18815	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EHE19_RS18820	COG0440	acetolactate synthase activity
EHE19_RS18825	COG0028	Belongs to the TPP enzyme family
EHE19_RS18835	COG0590	tRNA wobble adenosine to inosine editing
EHE19_RS18845	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EHE19_RS18850	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EHE19_RS18855	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EHE19_RS18865	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EHE19_RS18870	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EHE19_RS18885	COG5278	phosphoserine phosphatase activity
EHE19_RS18885	COG0840	transmembrane signaling receptor activity
EHE19_RS18895	COG0736	holo-[acyl-carrier-protein] synthase activity
EHE19_RS18900	COG0604	alcohol dehydrogenase
EHE19_RS18900	COG3321	synthase
EHE19_RS18905	COG0318	PFAM AMP-dependent synthetase and ligase
EHE19_RS18915	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EHE19_RS18920	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EHE19_RS18945	COG1215	transferase activity, transferring glycosyl groups
EHE19_RS18950	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EHE19_RS18960	COG0463	Glycosyl transferase, family 2
EHE19_RS18960	COG0457	Tetratricopeptide repeat
EHE19_RS18970	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
EHE19_RS18975	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EHE19_RS19030	COG0022	dehydrogenase e1 component
EHE19_RS19035	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EHE19_RS19045	COG0495	leucyl-tRNA aminoacylation
EHE19_RS19060	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EHE19_RS19065	COG1368	sulfuric ester hydrolase activity
EHE19_RS19070	COG2309	aminopeptidase activity
EHE19_RS19075	COG1164	Oligoendopeptidase f
EHE19_RS19085	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EHE19_RS19100	COG0464	growth
EHE19_RS19120	COG0791	NLP P60 protein
EHE19_RS19195	COG0740	serine-type endopeptidase activity
EHE19_RS19270	COG1475	DNA binding
EHE19_RS19290	COG2002	toxin-antitoxin pair type II binding
EHE19_RS19315	COG0582	viral genome integration into host DNA
EHE19_RS19345	COG3153	acetyltransferase
EHE19_RS19390	COG1215	transferase activity, transferring glycosyl groups
EHE19_RS19395	COG0463	Glycosyl transferase, family 2
EHE19_RS19420	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EHE19_RS19430	COG1597	lipid kinase activity
EHE19_RS19440	COG0157	Belongs to the NadC ModD family
EHE19_RS19445	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EHE19_RS19450	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EHE19_RS19470	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EHE19_RS19475	COG1475	DNA binding
EHE19_RS19480	COG0357	Ribosomal RNA small subunit methyltransferase G
EHE19_RS19485	COG0445	tRNA wobble uridine modification
EHE19_RS19490	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EHE19_RS19495	COG1847	R3H domain protein
EHE19_RS19500	COG0706	membrane insertase activity
EHE19_RS19505	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EHE19_RS19510	COG0594	ribonuclease P activity
EHE19_RS19515	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EHE19_RS19525	COG0025	NhaP-type Na H and K H
EHE19_RS19615	COG0464	growth