locus-tag	class	description
GKP14_RS00120	ENOG4105C0B	DNA polymerase III (alpha subunit)
GKP14_RS00130	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
GKP14_RS00145	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
GKP14_RS00165	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
GKP14_RS00170	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
GKP14_RS00175	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
GKP14_RS00180	ENOG4105DX0	Hemolysin A
GKP14_RS00185	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
GKP14_RS00190	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
GKP14_RS00195	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
GKP14_RS00210	ENOG4108Q5Y	Membrane
GKP14_RS00215	ENOG4105KG3	cytidine deaminase
GKP14_RS00230	ENOG4105CJ2	(LipO)protein
GKP14_RS00250	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
GKP14_RS00255	ENOG4105D6A	Electron transport complex
GKP14_RS00260	ENOG41080WF	Electron transport complex, RnfABCDGE type, G subunit
GKP14_RS00265	ENOG4105DZB	Electron transport complex
GKP14_RS00270	ENOG4105DGN	Electron transport complex
GKP14_RS00275	ENOG4108R3D	Electron transport complex
GKP14_RS00290	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
GKP14_RS00295	ENOG4107VXZ	Hydrolase
GKP14_RS00300	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
GKP14_RS00305	ENOG4105CUZ	uba thif-type nad fad binding protein
GKP14_RS00320	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
GKP14_RS00325	ENOG4105CS2	ec 3.2.1.21
GKP14_RS00340	ENOG4105DZ1	carboxypeptidase
GKP14_RS00345	ENOG4105BZ1	(ABC) transporter
GKP14_RS00350	ENOG4105FH5	Membrane
GKP14_RS00355	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
GKP14_RS00360	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
GKP14_RS00385	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
GKP14_RS00390	ENOG4105E39	Enoyl-CoA hydratase
GKP14_RS00400	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
GKP14_RS00410	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
GKP14_RS00415	ENOG4108R6K	riboflavin synthase, subunit alpha
GKP14_RS00420	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
GKP14_RS00435	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
GKP14_RS00440	ENOG4107BJW	polysaccharide deacetylase
GKP14_RS00450	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
GKP14_RS00460	ENOG4105CI3	gtp-binding protein typa
GKP14_RS00480	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
GKP14_RS00490	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
GKP14_RS00500	ENOG4108UUM	single-stranded DNA-binding protein
GKP14_RS00510	ENOG4108QG2	Membrane
GKP14_RS00530	ENOG4105HDK	L-asparaginase
GKP14_RS00540	ENOG4105C5H	ABC transporter
GKP14_RS00545	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
GKP14_RS00555	ENOG4105BZG	amino acid carrier protein
GKP14_RS00580	ENOG4105CDW	Resistance protein
GKP14_RS00650	ENOG4105CMR	udp-glucose 4-epimerase
GKP14_RS00655	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
GKP14_RS00665	ENOG4107U9T	Pfam:Ribonuclease_BN
GKP14_RS00710	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
GKP14_RS00725	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
GKP14_RS00745	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
GKP14_RS00750	ENOG4105CNN	ABC, transporter
GKP14_RS00755	ENOG4105C2J	ABC transporter
GKP14_RS00760	ENOG4108RVA	ribokinase
GKP14_RS00770	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
GKP14_RS00775	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
GKP14_RS00780	ENOG4107Y70	Heat shock protein
GKP14_RS00785	ENOG4108RCM	Nitroreductase
GKP14_RS00800	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
GKP14_RS00825	ENOG4105CAH	Chromate
GKP14_RS00830	ENOG4107YDN	peptide deformylase
GKP14_RS00840	ENOG4105WH5	Teichoic acid glycosylation protein
GKP14_RS00850	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
GKP14_RS00865	ENOG4108JJB	ABC transporter
GKP14_RS00895	ENOG4105C2F	Histidine kinase
GKP14_RS00900	ENOG4107XVH	Transcriptional regulator
GKP14_RS00915	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
GKP14_RS00920	ENOG4105CG3	alpha amylase, catalytic region
GKP14_RS00955	ENOG4105DKQ	ROK family
GKP14_RS00960	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
GKP14_RS00965	ENOG4107SBW	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GKP14_RS00970	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GKP14_RS00975	ENOG4105XT2	Transcriptional regulator
GKP14_RS01040	ENOG4105VYW	UPF0251 protein
GKP14_RS01050	ENOG4105DQ6	Transposase
GKP14_RS01070	ENOG4105DQ6	Transposase
GKP14_RS01105	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
GKP14_RS01110	ENOG4105CTQ	phosphohexokinase
GKP14_RS01120	ENOG4108BN2	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
GKP14_RS01125	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
GKP14_RS01135	ENOG4105DTT	CRISPR-associated helicase, cas3
GKP14_RS01180	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
GKP14_RS01190	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
GKP14_RS01200	ENOG4105CNI	cell division protein FtsW
GKP14_RS01205	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
GKP14_RS01215	ENOG4105CJN	penicillin-binding protein
GKP14_RS01245	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
GKP14_RS01250	ENOG4105MS2	ribosomal subunit Interface protein
GKP14_RS01265	ENOG41060GV	RNA binding s1 domain protein
GKP14_RS01285	ENOG41082I2	s4 domain protein
GKP14_RS01290	ENOG4105G7B	Protein of unknown function (DUF2992)
GKP14_RS01295	ENOG4105K70	DNA-binding protein
GKP14_RS01300	ENOG4105DXN	mazG family
GKP14_RS01315	ENOG4105DBI	uridine monophosphokinase
GKP14_RS01320	ENOG4105D4P	Coproporphyrinogen iii oxidase
GKP14_RS01325	ENOG4107VMB	Beta-lactamase domain protein
GKP14_RS01330	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
GKP14_RS01335	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
GKP14_RS01345	ENOG4105C8B	TIGR00159 family
GKP14_RS01360	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
GKP14_RS01365	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
GKP14_RS01380	ENOG4107GRR	phosphate transport regulator
GKP14_RS01385	ENOG4105CJ3	phosphate transporter
GKP14_RS01390	ENOG4107VMI	polysaccharide deacetylase
GKP14_RS01415	ENOG4105E0A	ABC, transporter
GKP14_RS01420	ENOG4105EHG	Permease protein
GKP14_RS01430	ENOG410810Y	Sulfite reductase
GKP14_RS01435	ENOG4105C3M	thioredoxin reductase
GKP14_RS01440	ENOG4108Z0R	Transferase
GKP14_RS01470	ENOG4105CJ1	ABC, transporter
GKP14_RS01475	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GKP14_RS01485	ENOG4105CZV	ABC transporter
GKP14_RS01490	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
GKP14_RS01505	ENOG4108RDQ	ABC transporter
GKP14_RS01540	ENOG4108NEV	two component transcriptional regulator, LytTR family
GKP14_RS01545	ENOG4105CAQ	asparagine synthetase
GKP14_RS01590	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
GKP14_RS01595	ENOG4105XZU	Preprotein translocase, subunit SecG
GKP14_RS01600	ENOG4105CDA	abc transporter atp-binding protein
GKP14_RS01605	ENOG4105E5Q	amino acid AbC transporter
GKP14_RS01615	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GKP14_RS01620	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GKP14_RS01625	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
GKP14_RS01630	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
GKP14_RS01635	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
GKP14_RS01640	ENOG4105CDU	Replicative dna helicase
GKP14_RS01645	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
GKP14_RS01650	ENOG4105BZR	domain protein
GKP14_RS01655	ENOG4105CN5	Metallo-Beta-Lactamase
GKP14_RS01660	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GKP14_RS01670	ENOG4105S7A	ErfK ybiS ycfS ynhG family protein
GKP14_RS01675	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
GKP14_RS01690	ENOG4107TB6	phosphoglycerate mutase
GKP14_RS01700	ENOG4108IUJ	4-alpha-glucanotransferase
GKP14_RS01720	ENOG4105ETE	Transcriptional regulator (LacI family
GKP14_RS01725	ENOG4108IJ2	phosphate acetyltransferase
GKP14_RS01730	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
GKP14_RS01755	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
GKP14_RS01760	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
GKP14_RS01810	ENOG4105ETE	Transcriptional regulator (LacI family
GKP14_RS01820	ENOG4105BZ1	(ABC) transporter
GKP14_RS01830	ENOG4105GVJ	transcriptional regulator
GKP14_RS01850	ENOG4105C1A	potassium transporter peripheral membrane
GKP14_RS01865	ENOG4105DAP	Nicotinate phosphoribosyltransferase
GKP14_RS01880	ENOG4105DSE	periplasmic solute binding protein
GKP14_RS01890	ENOG4105FAV	ABC, transporter
GKP14_RS01895	ENOG4108I0C	methyltransferase
GKP14_RS01900	ENOG4108NRW	Phospholipase, patatin family
GKP14_RS01920	ENOG4105CE4	GlcNAc 6-P deacetylase
GKP14_RS01925	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
GKP14_RS01930	ENOG4105C5Y	PTS System
GKP14_RS01950	ENOG4106KNT	transcriptional regulator
GKP14_RS01955	ENOG410667J	hydrolase
GKP14_RS01980	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
GKP14_RS01985	ENOG4105C6E	dna polymerase iii
GKP14_RS01995	ENOG4107QSE	Dipeptidase
GKP14_RS02025	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
GKP14_RS02035	ENOG4107QQG	Dehydrogenase
GKP14_RS02040	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
GKP14_RS02045	ENOG4105J5G	Transferase hexapeptide repeat containing protein
GKP14_RS02050	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
GKP14_RS02060	ENOG4105C6T	cysteine synthase
GKP14_RS02065	ENOG4108KGH	TRANSCRIPTIONal
GKP14_RS02070	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
GKP14_RS02080	ENOG4105F8V	Hydrolase, tatD family
GKP14_RS02085	ENOG4107RUE	extracellular solute-binding protein family 1
GKP14_RS02090	ENOG4105D38	putrescine abc transporter
GKP14_RS02095	ENOG4105F38	ABC transporter, permease
GKP14_RS02100	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GKP14_RS02110	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
GKP14_RS02115	ENOG4108UMI	ABC transporter, permease
GKP14_RS02120	ENOG4105D01	(LipO)protein
GKP14_RS02130	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
GKP14_RS02140	ENOG4105EPR	degv family
GKP14_RS02145	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
GKP14_RS02150	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
GKP14_RS02155	ENOG41083V3	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
GKP14_RS02165	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
GKP14_RS02170	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
GKP14_RS02175	ENOG4105VBH	UPF0297 protein
GKP14_RS02185	ENOG4107QNG	Phosphoribosylglycinamide synthetase
GKP14_RS02200	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
GKP14_RS02210	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
GKP14_RS02235	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
GKP14_RS02240	ENOG4106H78	methyltransferase
GKP14_RS02250	ENOG4105KRI	phosphocarrier protein (HPr
GKP14_RS02265	ENOG4105VB6	UPF0109 protein
GKP14_RS02270	ENOG4105K5M	30s ribosomal protein S16
GKP14_RS02280	ENOG4105VBN	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity)
GKP14_RS02295	ENOG4105BZG	amino acid carrier protein
GKP14_RS02305	ENOG4105C7N	Xanthine uracil vitamin C permease
GKP14_RS02315	ENOG4108Z66	YbaK ebsC protein
GKP14_RS02325	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
GKP14_RS02330	ENOG410667J	hydrolase
GKP14_RS02340	ENOG4108TVT	permease
GKP14_RS02345	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
GKP14_RS02350	ENOG4108Z3G	3H domain protein
GKP14_RS02365	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
GKP14_RS02370	ENOG41068JE	domain protein
GKP14_RS02390	ENOG4105C5H	ABC transporter
GKP14_RS02395	ENOG4105WEF	catalase
GKP14_RS02400	ENOG4108VK3	Cupin 2 Conserved Barrel Domain Protein
GKP14_RS02440	ENOG4105K4I	Scp-like extracellular
GKP14_RS02490	ENOG4105C3F	Signal peptidase i
GKP14_RS02505	ENOG4105DY9	regulatoR
GKP14_RS02510	ENOG4105BZ1	(ABC) transporter
GKP14_RS02520	ENOG4107T14	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
GKP14_RS02525	ENOG4105DTQ	mandelate racemase muconate lactonizing
GKP14_RS02530	ENOG4108ZT0	50S ribosomal protein l17
GKP14_RS02540	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
GKP14_RS02550	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GKP14_RS02555	ENOG41067V7	50S ribosomal protein L36
GKP14_RS02575	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
GKP14_RS02580	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
GKP14_RS02585	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
GKP14_RS02600	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
GKP14_RS02605	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
GKP14_RS02615	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
GKP14_RS02620	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GKP14_RS02625	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
GKP14_RS02630	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
GKP14_RS02635	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
GKP14_RS02640	ENOG41082SA	50s ribosomal protein l29
GKP14_RS02655	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
GKP14_RS02660	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
GKP14_RS02665	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GKP14_RS02675	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
GKP14_RS02680	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
GKP14_RS02690	ENOG4105X1N	Glycosyl transferase family 8
GKP14_RS02705	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
GKP14_RS02710	ENOG4105E2X	shikimate dehydrogenase
GKP14_RS02715	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
GKP14_RS02725	ENOG4105D49	3-dehydroquinate synthase
GKP14_RS02730	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
GKP14_RS02735	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
GKP14_RS02740	ENOG4105CQC	Prephenate dehydratase
GKP14_RS02745	ENOG4105KME	endoribonuclease L-psp
GKP14_RS02755	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
GKP14_RS02765	ENOG4108JJB	ABC transporter
GKP14_RS02775	ENOG4105EYH	Exonuclease
GKP14_RS02780	ENOG4107RFY	SbcCD D subunit
GKP14_RS02785	ENOG4105DZ1	carboxypeptidase
GKP14_RS02790	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
GKP14_RS02795	ENOG4108VZM	50s ribosomal protein L10
GKP14_RS02810	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
GKP14_RS02820	ENOG4105WDJ	50S ribosomal protein L33
GKP14_RS02830	ENOG4105CPF	Cell wall formation (By similarity)
GKP14_RS02835	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
GKP14_RS02845	ENOG4105C75	arginyL-tRNA synthetase
GKP14_RS02855	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
GKP14_RS02870	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
GKP14_RS02880	ENOG4105CFF	transcriptional regulator
GKP14_RS02890	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
GKP14_RS02905	ENOG4107R91	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
GKP14_RS02935	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
GKP14_RS02960	ENOG4105BZA	Phosphoglycerate kinase
GKP14_RS02980	ENOG4108IGT	Dipeptidase
GKP14_RS02995	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
GKP14_RS03000	ENOG4105C0H	protease
GKP14_RS03015	ENOG4107TH8	cina domain protein
GKP14_RS03020	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
GKP14_RS03025	ENOG4107QI6	Cysteine desulfurase
GKP14_RS03030	ENOG4108QBV	Monogalactosyldiacylglycerol synthase
GKP14_RS03040	ENOG4105K64	Glycosyl transferase, family 2
GKP14_RS03050	ENOG41090VF	Stage v sporulation protein ac
GKP14_RS03055	ENOG4105CZ3	stage V sporulation protein ad
GKP14_RS03070	ENOG4107YM4	Beta-lactamase domain-containing protein
GKP14_RS03080	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
GKP14_RS03090	ENOG4105C2M	dna polymerase I
GKP14_RS03095	ENOG4105DHI	Methyltransferase
GKP14_RS03105	ENOG4108IMY	Transcriptional regulator
GKP14_RS03120	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
GKP14_RS03125	ENOG4105CHR	reductase
GKP14_RS03130	ENOG4107QSI	ABC, transporter
GKP14_RS03135	ENOG4105DMF	Dehydrogenase
GKP14_RS03145	ENOG4105CID	antiterminator
GKP14_RS03150	ENOG4105DQ6	Transposase
GKP14_RS03160	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
GKP14_RS03180	ENOG4105XSJ	toxin secretion phage lysis holin
GKP14_RS03240	ENOG4105EMU	Dehydrogenase
GKP14_RS03260	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
GKP14_RS03265	ENOG4105CAK	Cell division ATP-binding protein ftsE
GKP14_RS03270	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
GKP14_RS03290	ENOG4108UZE	carboxy-peptidase
GKP14_RS03300	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
GKP14_RS03305	ENOG4105CH7	arginosuccinase
GKP14_RS03310	ENOG4105DM4	PTS System
GKP14_RS03340	ENOG4105C7K	acetolactate synthase
GKP14_RS03345	ENOG4108ZP8	Acetolactate synthase small subunit
GKP14_RS03350	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
GKP14_RS03375	ENOG4108PQP	glycosyl transferase group 1
GKP14_RS03405	ENOG4105KIP	Thioesterase
GKP14_RS03415	ENOG4105YB8	TM2 domain containing protein
GKP14_RS03420	ENOG4105C3G	gtp-binding protein
GKP14_RS03425	ENOG4108RAC	Rubrerythrin
GKP14_RS03435	ENOG4108Z6B	deaminase
GKP14_RS03445	ENOG4105UQX	Mate efflux family protein
GKP14_RS03455	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
GKP14_RS03520	ENOG4105CHM	Aminotransferase
GKP14_RS03530	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
GKP14_RS03535	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
GKP14_RS03565	ENOG4107R4J	Chloride channel
GKP14_RS03600	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
GKP14_RS03610	ENOG4105WG9	Conserved Protein
GKP14_RS03630	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
GKP14_RS03645	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
GKP14_RS03655	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
GKP14_RS03660	ENOG4105CHV	Transcription elongation factor NusA
GKP14_RS03670	ENOG4108M14	stage v sporulation protein t
GKP14_RS03695	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
GKP14_RS03705	ENOG4105VKD	bioY protein
GKP14_RS03715	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
GKP14_RS03755	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
GKP14_RS03760	ENOG4105C31	Tryptophanyl-tRNA synthetase
GKP14_RS03815	ENOG4107414	GntR family transcriptional regulator
GKP14_RS03820	ENOG4105CG3	alpha amylase, catalytic region
GKP14_RS03825	ENOG4105C5Y	PTS System
GKP14_RS03835	ENOG4105FQP	Beta-lactamase
GKP14_RS03845	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
GKP14_RS03865	ENOG4105XSJ	toxin secretion phage lysis holin
GKP14_RS03890	ENOG4107QI6	Cysteine desulfurase
GKP14_RS03925	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
GKP14_RS03930	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
GKP14_RS03935	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
GKP14_RS03960	ENOG41073TP	transcriptional regulator
GKP14_RS03965	ENOG4105KZ7	phosphocarrier protein hpr
GKP14_RS03970	ENOG4105DM4	PTS System
GKP14_RS03975	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
GKP14_RS03980	ENOG4105ETD	TRANSCRIPTIONal
GKP14_RS03985	ENOG410841Q	phosphoesterase PA-phosphatase related protein
GKP14_RS04040	ENOG4105CXI	aluminum resistance protein
GKP14_RS04065	ENOG4105DBV	ornithine carbamoyltransferase
GKP14_RS04070	ENOG4105C8Y	Acetylornithine aminotransferase
GKP14_RS04075	ENOG4105CAS	nag kinase
GKP14_RS04080	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
GKP14_RS04085	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
GKP14_RS04105	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
GKP14_RS04185	ENOG4105C0H	protease
GKP14_RS04190	ENOG4105BZU	Histidine kinase
GKP14_RS04195	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GKP14_RS04220	ENOG4105CRK	lysyL-tRNA synthetase
GKP14_RS04225	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
GKP14_RS04240	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GKP14_RS04250	ENOG4105CSA	Coproporphyrinogen iii oxidase
GKP14_RS04280	ENOG4105CEF	Initiates the rapid degradation of small, acid-soluble proteins during spore germination (By similarity)
GKP14_RS04285	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
GKP14_RS04310	ENOG410838F	Glycosyl transferase family 2
GKP14_RS04320	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GKP14_RS04325	ENOG4105E65	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GKP14_RS04340	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
GKP14_RS04345	ENOG4105D01	(LipO)protein
GKP14_RS04350	ENOG4108UMI	ABC transporter, permease
GKP14_RS04355	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
GKP14_RS04360	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
GKP14_RS04370	ENOG4105C2N	RNA methyltransferase TrmH family group 3
GKP14_RS04380	ENOG4105D2N	Aldolase
GKP14_RS04395	ENOG4105DXH	Alcohol dehydrogenase zinc-binding domain protein
GKP14_RS04400	ENOG4105DE4	1-phosphofructokinase
GKP14_RS04410	ENOG4105KRI	phosphocarrier protein (HPr
GKP14_RS04420	ENOG4105ETD	TRANSCRIPTIONal
GKP14_RS04425	ENOG4105CTS	PTS system mannitol-specific
GKP14_RS04445	ENOG4105BZU	Histidine kinase
GKP14_RS04450	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
GKP14_RS04455	ENOG4107URF	beta-phospho-glucomutase
GKP14_RS04485	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
GKP14_RS04500	ENOG4105CFP	Peptidase U32
GKP14_RS04505	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
GKP14_RS04510	ENOG4105DFF	Rod shape-determining protein mreb
GKP14_RS04525	ENOG4107RF6	penicillin-binding protein
GKP14_RS04530	ENOG4107U53	septum site-determining protein minD
GKP14_RS04535	ENOG4108Z5K	methylglyoxal synthase
GKP14_RS04540	ENOG4105CUT	histidyl-tRNA synthetase
GKP14_RS04550	ENOG4105WPN	DNA integration recombination invertion protein
GKP14_RS04555	ENOG4105KVH	Transcriptional regulator
GKP14_RS04560	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
GKP14_RS04570	ENOG4105F1A	Pyruvate formate-lyase
GKP14_RS04580	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
GKP14_RS04590	ENOG4105MA4	psp1 domain protein
GKP14_RS04600	ENOG4105X0R	protein from nitrogen regulatory protein P-II
GKP14_RS04605	ENOG4105CXN	decarboxylase
GKP14_RS04610	ENOG4108KGH	TRANSCRIPTIONal
GKP14_RS04625	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GKP14_RS04630	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GKP14_RS04650	ENOG4108JA2	transcriptioN-repair coupling factor
GKP14_RS04655	ENOG4105C8J	)-transporter
GKP14_RS04665	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
GKP14_RS04675	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
GKP14_RS04690	ENOG4105E98	transcriptional regulator DeoR family
GKP14_RS04695	ENOG4105DE4	1-phosphofructokinase
GKP14_RS04700	ENOG4105DM4	PTS System
GKP14_RS04705	ENOG4105C7Z	Conserved Protein
GKP14_RS04710	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
GKP14_RS04725	ENOG4108JU3	Alkyl hydroperoxide reductase
GKP14_RS04740	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GKP14_RS04750	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GKP14_RS04780	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
GKP14_RS04790	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
GKP14_RS04800	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
GKP14_RS04805	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
GKP14_RS04810	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GKP14_RS04815	ENOG4108Z7S	Single-stranded nucleic acid binding R3H domain-containing protein
GKP14_RS04820	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
GKP14_RS04825	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
GKP14_RS04840	ENOG4107QJE	Chromosome Partitioning Protein
GKP14_RS04845	ENOG4105FA0	parb-like partition protein
GKP14_RS04850	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
GKP14_RS04860	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GKP14_RS04930	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
GKP14_RS04940	ENOG4105MT0	Sporulation transcriptional regulator spoiiid
GKP14_RS04950	ENOG4105FRN	stage II sporulation protein
GKP14_RS04955	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
GKP14_RS04960	ENOG4105DWF	phosphomethylpyrimidine kinase
GKP14_RS04975	ENOG4105CB5	ATP-dependent DNA helicase recG
GKP14_RS04980	ENOG4105DP4	dak2 domain fusion protein ylov
GKP14_RS04985	ENOG4105D48	metallophosphoesterase
GKP14_RS04990	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
GKP14_RS04995	ENOG4105C22	threonyL-tRNA synthetase
GKP14_RS05000	ENOG4105C7K	acetolactate synthase
GKP14_RS05010	ENOG4105C7B	Threonine dehydratase
GKP14_RS05025	ENOG4105D82	Glutamate dehydrogenase
GKP14_RS05035	ENOG4105CNW	domain protein
GKP14_RS05040	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
GKP14_RS05055	ENOG4105BZU	Histidine kinase
GKP14_RS05060	ENOG4105CBJ	Metal-dependent enzyme
GKP14_RS05065	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
GKP14_RS05075	ENOG4105D7W	serine acetyltransferase
GKP14_RS05080	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
GKP14_RS05085	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
GKP14_RS05090	ENOG410902V	Modulates RecA activity (By similarity)
GKP14_RS05095	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
GKP14_RS05100	ENOG4105C59	p-type ATPase
GKP14_RS05110	ENOG4105C59	p-type ATPase
GKP14_RS05150	ENOG4105QUH	Domain of unknown function (DUF2088)
GKP14_RS05155	ENOG4105CQB	FAD linked oxidase domain protein
GKP14_RS05160	ENOG4105BZJ	Electron transfer flavoprotein
GKP14_RS05165	ENOG4105C10	Electron transfer flavoprotein
GKP14_RS05170	ENOG4105C1G	acyl-Coa dehydrogenase
GKP14_RS05210	ENOG4105KXQ	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
GKP14_RS05230	ENOG4108UVJ	appr-1-p processing domain protein
GKP14_RS05235	ENOG4105GFG	DUF218 domain
GKP14_RS05245	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
GKP14_RS05255	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
GKP14_RS05290	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
GKP14_RS05295	ENOG4105EVY	Uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent (By similarity)
GKP14_RS05305	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
GKP14_RS05325	ENOG4105DIW	FeS assembly protein SUFB
GKP14_RS05330	ENOG4105JRK	feS assembly protein SufD
GKP14_RS05340	ENOG4107YH3	SUF system FeS assembly protein, NifU family
GKP14_RS05350	ENOG4105DBI	uridine monophosphokinase
GKP14_RS05360	ENOG4105DKQ	ROK family
GKP14_RS05365	ENOG4105DG6	mannose-6-phosphate isomerase
GKP14_RS05375	ENOG4107R28	alpha amylase, catalytic region
GKP14_RS05395	ENOG4105ETE	Transcriptional regulator (LacI family
GKP14_RS05405	ENOG4105C71	hydrolase family 65, central catalytic
GKP14_RS05415	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
GKP14_RS05420	ENOG4105DRS	transport system, permease
GKP14_RS05425	ENOG4105CJQ	hydrolase, family 31
GKP14_RS05430	ENOG4107URF	beta-phospho-glucomutase
GKP14_RS05460	ENOG4105DQ6	Transposase
GKP14_RS05470	ENOG4105VDH	Dihydroxyacetone kinase
GKP14_RS05475	ENOG4108UTZ	Dihydroxyacetone kinase
GKP14_RS05480	ENOG4105CMT	Dihydroxyacetone kinase
GKP14_RS05490	ENOG4108ZIA	glycerol-3-phosphate responsive antiterminator
GKP14_RS05510	ENOG4108IFG	nitrite reductase, (NAD(P)H)
GKP14_RS05530	ENOG41085AS	UPF0473 protein
GKP14_RS05535	ENOG4105C6K	Malic enzyme
GKP14_RS05545	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
GKP14_RS05550	ENOG4108JQ1	Dehydrogenase
GKP14_RS05555	ENOG4105CD3	dihydroorotase
GKP14_RS05560	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
GKP14_RS05565	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
GKP14_RS05570	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
GKP14_RS05575	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
GKP14_RS05580	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
GKP14_RS05595	ENOG4105CJN	penicillin-binding protein
GKP14_RS05605	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
GKP14_RS05625	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
GKP14_RS05630	ENOG4105DVE	abc transporter atp-binding protein
GKP14_RS05640	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
GKP14_RS05660	ENOG4105C7J	ABC transporter, permease
GKP14_RS05665	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
GKP14_RS05675	ENOG4108UIC	UPF0340 protein
GKP14_RS05690	ENOG4106PMH	Extracellular solute-binding protein family 3
GKP14_RS05700	ENOG4105CDA	abc transporter atp-binding protein
GKP14_RS05710	ENOG4105CA9	Pyruvate kinase
GKP14_RS05720	ENOG41082DI	50s ribosomal protein l31
GKP14_RS05725	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
GKP14_RS05730	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
GKP14_RS05735	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
GKP14_RS05740	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GKP14_RS05775	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
GKP14_RS05800	ENOG4105C7H	Helicase, RecD TraA family
GKP14_RS05805	ENOG4105MJ2	Competence protein
GKP14_RS05815	ENOG4105DFU	Cell wall formation (By similarity)
GKP14_RS05830	ENOG4105CE9	30S ribosomal protein S2
GKP14_RS05835	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
GKP14_RS05850	ENOG4105VEQ	Cold shock protein
GKP14_RS05915	ENOG4107QW8	radical SAM domain protein
GKP14_RS05920	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
GKP14_RS05925	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
GKP14_RS05930	ENOG4105C8M	UPF0272 protein
GKP14_RS05940	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
GKP14_RS05950	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
GKP14_RS05955	ENOG4105CNW	domain protein
GKP14_RS05960	ENOG4105C1G	acyl-Coa dehydrogenase
GKP14_RS05975	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
GKP14_RS05980	ENOG4105FH5	Membrane
GKP14_RS05985	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
GKP14_RS06000	ENOG4105EWM	Histidine kinase
GKP14_RS06005	ENOG4105CJZ	response regulator
GKP14_RS06010	ENOG4105II7	pyrroline-5-carboxylate reductase
GKP14_RS06015	ENOG4108JQ7	(ABC) transporter
GKP14_RS06025	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GKP14_RS06030	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GKP14_RS06040	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
GKP14_RS06045	ENOG4107TFB	basic membrane
GKP14_RS06050	ENOG4108JQ9	ABC transporter
GKP14_RS06055	ENOG4105UIB	(ABC) transporter
GKP14_RS06075	ENOG4105C1J	atp-dependent rna helicase
GKP14_RS06105	ENOG4105CSR	polyphosphate kinase 2
GKP14_RS06110	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
GKP14_RS06120	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
GKP14_RS06125	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
GKP14_RS06130	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
GKP14_RS06140	ENOG4108JJB	ABC transporter
GKP14_RS06165	ENOG4108UKJ	Cdp-alcohol phosphatidyltransferase
GKP14_RS06210	ENOG4108R6W	Transcriptional regulator, ARAC family
GKP14_RS06215	ENOG4105C4R	Atp-dependent dna helicase
GKP14_RS06225	ENOG41087GE	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
GKP14_RS06230	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
GKP14_RS06240	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
GKP14_RS06245	ENOG4105HHA	aminodeoxychorismate lyase
GKP14_RS06250	ENOG4105CFP	Peptidase U32
GKP14_RS06255	ENOG4105CJN	penicillin-binding protein
GKP14_RS06265	ENOG4107YU2	histidine triad (hIT) protein
GKP14_RS06270	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
GKP14_RS06285	ENOG4105HVR	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity)
GKP14_RS06300	ENOG4105CTZ	aminopeptidase c
GKP14_RS06315	ENOG4108115	UPF0145 protein
GKP14_RS06335	ENOG4105DAV	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GKP14_RS06340	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
GKP14_RS06350	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
GKP14_RS06355	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
GKP14_RS06360	ENOG4105DC7	peptidase M24
GKP14_RS06370	ENOG4108JIC	nucleoside recognition domain protein
GKP14_RS06375	ENOG4108M14	stage v sporulation protein t
GKP14_RS06390	ENOG4105DR4	Methyltransferase
GKP14_RS06405	ENOG4105VDK	protein, conserved in bacteria
GKP14_RS06415	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GKP14_RS06420	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
GKP14_RS06425	ENOG4105E4C	Lytic transglycosylase catalytic
GKP14_RS06430	ENOG4105DFM	M18 family aminopeptidase
GKP14_RS06435	ENOG4107QW4	alcohol dehydrogenase
GKP14_RS06450	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GKP14_RS06455	ENOG4105BZU	Histidine kinase
GKP14_RS06460	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
GKP14_RS06470	ENOG4105DZ1	carboxypeptidase
GKP14_RS06475	ENOG4105EB3	Histidine kinase
GKP14_RS06480	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GKP14_RS06485	ENOG4105EYF	MMPL domain protein
GKP14_RS06495	ENOG41082AN	stage II sporulation protein
GKP14_RS06500	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
GKP14_RS06505	ENOG4105CT2	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GKP14_RS06690	ENOG4105EG2	ABC transporter, permease
GKP14_RS06695	ENOG4107FKK	extracellular solute-binding protein family 1
GKP14_RS06720	ENOG4105CXT	aspartate transcarbamylase
GKP14_RS06730	ENOG4105DMC	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3
GKP14_RS06735	ENOG4105CVA	phosphate
GKP14_RS06740	ENOG4105C8U	phosphate abc transporter
GKP14_RS06745	ENOG4105E2Z	phosphate ABC transporter (Permease
GKP14_RS06750	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
GKP14_RS06755	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
GKP14_RS06760	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GKP14_RS06765	ENOG4105BZU	Histidine kinase
GKP14_RS06775	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
GKP14_RS06780	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
GKP14_RS06785	ENOG4105CDE	UPF0348 protein
GKP14_RS06805	ENOG4107RVV	histidinol phosphate phosphatase, hisj family
GKP14_RS06810	ENOG4108ZB6	transcriptional regulator AsnC family
GKP14_RS06815	ENOG4105CHM	Aminotransferase
GKP14_RS06820	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
GKP14_RS06835	ENOG4105E1K	spore germination protein
GKP14_RS06840	ENOG4105CNI	cell division protein FtsW
GKP14_RS06845	ENOG4105CKU	formyltetrahydrofolate synthetase
GKP14_RS06855	ENOG41072GX	Peptidase M22 Glycoprotease
GKP14_RS06860	ENOG4108YZG	isomerase
GKP14_RS06880	ENOG4105SYT	Methylenetetrahydrofolate reductase
GKP14_RS06890	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
GKP14_RS06915	ENOG4105CD2	stage iii sporulation protein aa
GKP14_RS06930	ENOG4105KQ4	Stage iii sporulation protein ad
GKP14_RS06955	ENOG4105M7K	Involved in the transcription termination process (By similarity)
GKP14_RS06960	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GKP14_RS06970	ENOG41084DP	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
GKP14_RS06975	ENOG4108WVK	Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity)
GKP14_RS06985	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
GKP14_RS07005	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GKP14_RS07020	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
GKP14_RS07025	ENOG4105CM2	brancheD-chain amino acid aminotransferase
GKP14_RS07030	ENOG4105C34	Pseudouridine synthase
GKP14_RS07040	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
GKP14_RS07050	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
GKP14_RS07055	ENOG4105Q2H	domain protein
GKP14_RS07070	ENOG4105CHM	Aminotransferase
GKP14_RS07080	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
GKP14_RS07085	ENOG4105C8V	SAICAR synthetase
GKP14_RS07095	ENOG4105C83	adenylosuccinate lyase
GKP14_RS07100	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
GKP14_RS07135	ENOG4108RDQ	ABC transporter
GKP14_RS07165	ENOG4105DND	Transcriptional regulator
GKP14_RS07180	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
GKP14_RS07195	ENOG4108UW5	maltose o-acetyltransferase
GKP14_RS07215	ENOG410667J	hydrolase
GKP14_RS07235	ENOG4105D1H	recombination factor protein RarA
GKP14_RS07245	ENOG4105CV1	Transketolase (EC 2.2.1.1)
GKP14_RS07250	ENOG4108IUS	Transketolase
GKP14_RS07260	ENOG4108JU6	CBS domain protein
GKP14_RS07280	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
GKP14_RS07325	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
GKP14_RS07330	ENOG4105CFH	Aspartokinase
GKP14_RS07335	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
GKP14_RS07355	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
GKP14_RS07365	ENOG4105DFA	alanine racemase domain protein
GKP14_RS07370	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
GKP14_RS07385	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
GKP14_RS07390	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
GKP14_RS07395	ENOG4105C34	Pseudouridine synthase
GKP14_RS07415	ENOG4108C33	Resolvase
GKP14_RS07440	ENOG4105D6J	arsenicaL-resistance protein
GKP14_RS07445	ENOG41082BM	Transcriptional regulator, arsr family
GKP14_RS07450	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
GKP14_RS07470	ENOG41089UC	methyltransferase, type 11
GKP14_RS07480	ENOG4107SWG	transcriptional regulator MERR family
GKP14_RS07485	ENOG4105C4B	ABC transporter, permease
GKP14_RS07490	ENOG41083J0	(ABC) transporter
GKP14_RS07505	ENOG4107T5V	SNARE associated Golgi
GKP14_RS07535	ENOG4105C59	p-type ATPase
GKP14_RS07600	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
GKP14_RS07625	ENOG4107RHI	Cytosine-specific methyltransferase
GKP14_RS07710	ENOG4105K4W	Could be involved in septation (By similarity)
GKP14_RS07785	ENOG4105KY8	Rubrerythrin
GKP14_RS07795	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
GKP14_RS07800	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
GKP14_RS07805	ENOG4107T8Q	Glycosyl transferase (Group 1
GKP14_RS07810	ENOG4107QRS	glycosyltransferase group 2 family protein
GKP14_RS07815	ENOG4105CBX	hi0933 family
GKP14_RS07820	ENOG4105DZ0	fad dependent oxidoreductase
GKP14_RS07840	ENOG4105DZ1	carboxypeptidase
GKP14_RS07860	ENOG41067VY	50S ribosomal protein L32
GKP14_RS07870	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
GKP14_RS07875	ENOG4105VB9	50S ribosomal protein l28
GKP14_RS07880	ENOG4108Z4T	Peptidase M50
GKP14_RS07885	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
GKP14_RS07900	ENOG4105KBJ	sporulation protein ytfj
GKP14_RS07905	ENOG4105DZ1	carboxypeptidase
GKP14_RS07910	ENOG4105FE9	pseudouridine synthase
GKP14_RS07915	ENOG4105DSJ	YicC domain protein
GKP14_RS07925	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
GKP14_RS07930	ENOG41067UH	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
GKP14_RS07935	ENOG4105C25	Primosomal protein n'
GKP14_RS07940	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
GKP14_RS07945	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
GKP14_RS07955	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
GKP14_RS07965	ENOG4108ZF3	Phosphatase
GKP14_RS07970	ENOG4105D9P	serine threonine protein kinase
GKP14_RS07975	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
GKP14_RS08000	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
GKP14_RS08005	ENOG4105BZ8	glutamate synthase
GKP14_RS08030	ENOG4105CVQ	ATP-dependent Clp protease, proteolytic subunit
GKP14_RS08035	ENOG4105CNU	cell division protein FtsK
GKP14_RS08050	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GKP14_RS08055	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
GKP14_RS08065	ENOG4105C3F	Signal peptidase i
GKP14_RS08070	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
GKP14_RS08075	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GKP14_RS08080	ENOG41082RQ	UPF0102 protein
GKP14_RS08085	ENOG4107QID	Threonine synthase
GKP14_RS08095	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
GKP14_RS08100	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
GKP14_RS08105	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
GKP14_RS08115	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
GKP14_RS08120	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
GKP14_RS08125	ENOG4105KGF	protein, YerC YecD
GKP14_RS08165	ENOG4105C3S	Mate efflux family protein
GKP14_RS08170	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
GKP14_RS08175	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
GKP14_RS08185	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GKP14_RS08195	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GKP14_RS08205	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
GKP14_RS08240	ENOG4107QK3	aspartate-semialdehyde dehydrogenase (EC 1.2.1.11
GKP14_RS08250	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
GKP14_RS08255	ENOG4105CFH	Aspartokinase
GKP14_RS08275	ENOG4105EGD	dinuclear metal center protein, YbgI family
GKP14_RS08305	ENOG4105C0P	Mg chelatase subunit ChlI
GKP14_RS08330	ENOG4105EJQ	L-serine dehydratase
GKP14_RS08340	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
GKP14_RS08345	ENOG4105W5Q	DNA repair protein (RadC
GKP14_RS08350	ENOG4105C34	Pseudouridine synthase
GKP14_RS08360	ENOG41083RF	phosphoribosyl-ATP pyrophosphatase
GKP14_RS08375	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
GKP14_RS08380	ENOG4105CIH	Imidazole acetol-phosphate transaminase
GKP14_RS08385	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
GKP14_RS08390	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
GKP14_RS08395	ENOG4108IQ6	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
GKP14_RS08400	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
GKP14_RS08405	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
GKP14_RS08410	ENOG4105DZP	Membrane-associated zinc metalloprotease
GKP14_RS08420	ENOG4105KNE	Phosphatidate cytidylyltransferase
GKP14_RS08430	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
GKP14_RS08450	ENOG4105DMD	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GKP14_RS08455	ENOG4107ZE5	PPIases accelerate the folding of proteins
GKP14_RS08470	ENOG4105CGK	Exodeoxyribonuclease III
GKP14_RS08475	ENOG4105CY0	Metallo-Beta-Lactamase
GKP14_RS08480	ENOG4105D9P	serine threonine protein kinase
GKP14_RS08490	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
GKP14_RS08515	ENOG4108NRW	Phospholipase, patatin family
GKP14_RS08525	ENOG4105C01	Dihydroxy-acid dehydratase
GKP14_RS08530	ENOG4107QQR	Sporulation
GKP14_RS08535	ENOG4105S1Z	Stage IV sporulation protein B
GKP14_RS08545	ENOG4105CIZ	coA-substrate-specific enzyme activase
GKP14_RS08550	ENOG4105EPR	degv family
GKP14_RS08565	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
GKP14_RS08575	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
GKP14_RS08580	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GKP14_RS08585	ENOG4105CHR	reductase
GKP14_RS08590	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
GKP14_RS08595	ENOG4105EA8	2-Nitropropane dioxygenase
GKP14_RS08600	ENOG41082KT	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
GKP14_RS08625	ENOG4108FUT	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
GKP14_RS08640	ENOG4105C8T	Leucyl-tRNA synthetase
GKP14_RS08645	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
GKP14_RS08650	ENOG4108WF2	Metal Dependent Phosphohydrolase
GKP14_RS08655	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
GKP14_RS08675	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
GKP14_RS08685	ENOG4105CAT	Cytidine monophosphate kinase
GKP14_RS08690	ENOG4105CBX	hi0933 family
GKP14_RS08705	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
GKP14_RS08715	ENOG4105CE1	Ferrous iron transport protein b
GKP14_RS08740	ENOG4105EWC	Purine nucleoside phosphorylase
GKP14_RS08745	ENOG4105CE1	Ferrous iron transport protein b
GKP14_RS08760	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
GKP14_RS08765	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GKP14_RS08770	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
GKP14_RS08780	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
GKP14_RS08785	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
GKP14_RS08790	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
GKP14_RS08795	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
GKP14_RS08815	ENOG4105VJV	50s ribosomal protein L35
GKP14_RS08820	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
GKP14_RS08825	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
GKP14_RS08850	ENOG4105K63	Thioredoxin
GKP14_RS08865	ENOG41066A3	ATP guanido phosphotransferase
GKP14_RS08885	ENOG4105DB7	PHP domain protein
GKP14_RS08890	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
GKP14_RS08895	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
GKP14_RS08900	ENOG4105C9M	aspartyl-trna synthetase
GKP14_RS08905	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
GKP14_RS08910	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
GKP14_RS08940	ENOG4107E6A	Cytochrome p-450
GKP14_RS08955	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
GKP14_RS08965	ENOG4105FB9	CRISPR-associated protein
GKP14_RS08985	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)