locus-tag	class	description
RUMAL_RS00010	COG0592	DNA-directed DNA polymerase activity
RUMAL_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
RUMAL_RS00040	COG0187	DNA topoisomerase II activity
RUMAL_RS00055	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
RUMAL_RS00080	COG1192	Involved in chromosome partitioning
RUMAL_RS00095	COG0653	protein targeting
RUMAL_RS00100	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
RUMAL_RS00105	COG2942	2-epimerase
RUMAL_RS00145	COG0463	Glycosyl transferase, family 2
RUMAL_RS00165	COG0572	uridine kinase
RUMAL_RS00170	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
RUMAL_RS00170	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
RUMAL_RS00170	COG1013	pyruvate-flavodoxin oxidoreductase activity
RUMAL_RS00170	COG0674	pyruvate-flavodoxin oxidoreductase activity
RUMAL_RS00190	COG0051	transcription antitermination factor activity, RNA binding
RUMAL_RS00205	COG0089	rRNA binding
RUMAL_RS00215	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
RUMAL_RS00220	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
RUMAL_RS00225	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
RUMAL_RS00230	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
RUMAL_RS00235	COG0255	Belongs to the universal ribosomal protein uL29 family
RUMAL_RS00240	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
RUMAL_RS00245	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
RUMAL_RS00250	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
RUMAL_RS00255	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
RUMAL_RS00260	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
RUMAL_RS00265	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
RUMAL_RS00270	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
RUMAL_RS00280	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
RUMAL_RS00290	COG0200	Binds to the 23S rRNA
RUMAL_RS00300	COG0563	adenylate kinase activity
RUMAL_RS00305	COG0024	Methionine aminopeptidase
RUMAL_RS00315	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
RUMAL_RS00325	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
RUMAL_RS00330	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
RUMAL_RS00340	COG0202	RNA polymerase activity
RUMAL_RS00345	COG0203	ribosomal protein L17
RUMAL_RS00350	COG0745	RESPONSE REGULATOR receiver
RUMAL_RS00355	COG2246	polysaccharide biosynthetic process
RUMAL_RS00360	COG0110	maltose O-acetyltransferase activity
RUMAL_RS00385	COG0222	ribosome binding
RUMAL_RS00400	COG1136	(ABC) transporter
RUMAL_RS00415	COG2201	protein-glutamate methylesterase activity
RUMAL_RS00455	COG0588	phosphoglycerate mutase activity
RUMAL_RS00465	COG0149	triose-phosphate isomerase activity
RUMAL_RS00470	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
RUMAL_RS00475	COG0445	tRNA wobble uridine modification
RUMAL_RS00480	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
RUMAL_RS00490	COG1098	S1 RNA binding domain
RUMAL_RS00510	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
RUMAL_RS00515	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
RUMAL_RS00550	COG0424	maF-like protein
RUMAL_RS00555	COG2385	sporulation resulting in formation of a cellular spore
RUMAL_RS00560	COG3409	Peptidoglycan-binding domain 1 protein
RUMAL_RS00560	COG3773	Cell wall hydrolase
RUMAL_RS00575	COG1546	Belongs to the CinA family
RUMAL_RS00575	COG1058	Belongs to the CinA family
RUMAL_RS00585	COG0301	tRNA thio-modification
RUMAL_RS00590	COG1104	cysteine desulfurase activity
RUMAL_RS00595	COG0295	cytidine deaminase activity
RUMAL_RS00600	COG0459	protein refolding
RUMAL_RS00605	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
RUMAL_RS00610	COG0745	RESPONSE REGULATOR receiver
RUMAL_RS00615	COG3850	Histidine kinase
RUMAL_RS00615	COG5002	protein histidine kinase activity
RUMAL_RS00645	COG1136	(ABC) transporter
RUMAL_RS00650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RUMAL_RS00655	COG0577	efflux transmembrane transporter activity
RUMAL_RS00690	COG4656	Part of a membrane complex involved in electron transport
RUMAL_RS00695	COG1396	sequence-specific DNA binding
RUMAL_RS00695	COG1917	Cupin 2, conserved barrel domain protein
RUMAL_RS00710	COG0564	pseudouridine synthase activity
RUMAL_RS00715	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
RUMAL_RS00720	COG2384	SAM-dependent methyltransferase
RUMAL_RS00745	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
RUMAL_RS00750	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
RUMAL_RS00755	COG0494	nUDIX hydrolase
RUMAL_RS00825	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RUMAL_RS00835	COG2201	protein-glutamate methylesterase activity
RUMAL_RS00870	COG1132	(ABC) transporter
RUMAL_RS00875	COG0577	efflux transmembrane transporter activity
RUMAL_RS00875	COG1136	(ABC) transporter
RUMAL_RS00905	COG0717	Belongs to the dCTP deaminase family
RUMAL_RS00930	COG3459	Glycosyltransferase 36 associated
RUMAL_RS00945	COG0246	Mannitol dehydrogenase
RUMAL_RS00955	COG0800	Aldolase
RUMAL_RS00960	COG1904	glucuronate isomerase
RUMAL_RS00965	COG1312	Catalyzes the dehydration of D-mannonate
RUMAL_RS00980	COG1592	Rubrerythrin
RUMAL_RS00985	COG2959	enzyme of heme biosynthesis
RUMAL_RS00990	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
RUMAL_RS00995	COG1131	(ABC) transporter
RUMAL_RS01005	COG1696	Membrane protein involved in D-alanine export
RUMAL_RS01055	COG0720	synthase
RUMAL_RS01060	COG0602	queuosine metabolic process
RUMAL_RS01070	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
RUMAL_RS01095	COG0778	Nitroreductase
RUMAL_RS01115	COG0456	acetyltransferase
RUMAL_RS01120	COG2226	methyltransferase
RUMAL_RS01125	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
RUMAL_RS01145	COG0395	ABC-type sugar transport system, permease component
RUMAL_RS01160	COG2002	toxin-antitoxin pair type II binding
RUMAL_RS01165	COG1720	tRNA m6t6A37 methyltransferase activity
RUMAL_RS01175	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
RUMAL_RS01200	COG1970	mechanosensitive ion channel activity
RUMAL_RS01205	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
RUMAL_RS01215	COG0071	Belongs to the small heat shock protein (HSP20) family
RUMAL_RS01220	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
RUMAL_RS01225	COG0268	Binds directly to 16S ribosomal RNA
RUMAL_RS01235	COG1132	(ABC) transporter
RUMAL_RS01240	COG1132	(ABC) transporter
RUMAL_RS01245	COG0083	homoserine kinase activity
RUMAL_RS01265	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
RUMAL_RS01270	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
RUMAL_RS01275	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
RUMAL_RS01285	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
RUMAL_RS01295	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
RUMAL_RS01305	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
RUMAL_RS01310	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
RUMAL_RS01315	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
RUMAL_RS01340	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
RUMAL_RS01345	COG0151	Belongs to the GarS family
RUMAL_RS01365	COG0138	bifunctional purine biosynthesis protein purh
RUMAL_RS01375	COG3196	Protein conserved in bacteria
RUMAL_RS01405	COG0280	phosphate acetyltransferase
RUMAL_RS01435	COG2198	Histidine kinase
RUMAL_RS01435	COG0643	Histidine kinase
RUMAL_RS01440	COG0835	chemotaxis
RUMAL_RS01445	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RUMAL_RS01445	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RUMAL_RS01450	COG0564	pseudouridine synthase activity
RUMAL_RS01460	COG0355	proton-transporting ATP synthase activity, rotational mechanism
RUMAL_RS01465	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
RUMAL_RS01470	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
RUMAL_RS01475	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
RUMAL_RS01485	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
RUMAL_RS01490	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
RUMAL_RS01495	COG0356	it plays a direct role in the translocation of protons across the membrane
RUMAL_RS01505	COG4124	Belongs to the glycosyl hydrolase 26 family
RUMAL_RS01525	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
RUMAL_RS01530	COG1132	(ABC) transporter
RUMAL_RS01535	COG1132	(ABC) transporter
RUMAL_RS01555	COG1242	4 iron, 4 sulfur cluster binding
RUMAL_RS01585	COG0574	Belongs to the PEP-utilizing enzyme family
RUMAL_RS01585	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
RUMAL_RS01595	COG4124	Belongs to the glycosyl hydrolase 26 family
RUMAL_RS01600	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
RUMAL_RS01600	COG3976	FMN-binding domain protein
RUMAL_RS01600	COG3976	FMN-binding domain protein
RUMAL_RS01600	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
RUMAL_RS01645	COG4124	Belongs to the glycosyl hydrolase 26 family
RUMAL_RS01665	COG2720	vancomycin resistance protein
RUMAL_RS01680	COG1523	belongs to the glycosyl hydrolase 13 family
RUMAL_RS01690	COG0688	phosphatidylethanolamine metabolic process
RUMAL_RS01700	COG1183	phosphatidylcholine synthase activity
RUMAL_RS01715	COG1131	(ABC) transporter
RUMAL_RS01735	COG1476	TRANSCRIPTIONal
RUMAL_RS01750	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
RUMAL_RS01750	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
RUMAL_RS01840	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RUMAL_RS01845	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RUMAL_RS01865	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
RUMAL_RS01875	COG0346	lactoylglutathione lyase activity
RUMAL_RS01885	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RUMAL_RS01900	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
RUMAL_RS01905	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
RUMAL_RS01935	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
RUMAL_RS01975	COG2755	lipolytic protein G-D-S-L family
RUMAL_RS01985	COG1181	Belongs to the D-alanine--D-alanine ligase family
RUMAL_RS02020	COG0438	transferase activity, transferring glycosyl groups
RUMAL_RS02080	COG1088	dTDP-glucose 4,6-dehydratase activity
RUMAL_RS02090	COG1091	dTDP-4-dehydrorhamnose reductase activity
RUMAL_RS02110	COG0667	Aldo Keto reductase
RUMAL_RS02115	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
RUMAL_RS02120	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
RUMAL_RS02135	COG1837	Belongs to the UPF0109 family
RUMAL_RS02145	COG1959	2 iron, 2 sulfur cluster binding
RUMAL_RS02150	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
RUMAL_RS02155	COG0598	Magnesium transport protein CorA
RUMAL_RS02210	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
RUMAL_RS02215	COG0205	6-phosphofructokinase activity
RUMAL_RS02240	COG0463	Glycosyl transferase, family 2
RUMAL_RS02245	COG0045	succinate-CoA ligase (ADP-forming) activity
RUMAL_RS02255	COG0006	proline dipeptidase activity
RUMAL_RS02270	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
RUMAL_RS02320	COG0587	DNA-directed DNA polymerase activity
RUMAL_RS02330	COG1396	sequence-specific DNA binding
RUMAL_RS02335	COG0281	malic enzyme
RUMAL_RS02345	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
RUMAL_RS02350	COG5001	Diguanylate cyclase
RUMAL_RS02355	COG1609	Transcriptional regulator
RUMAL_RS02370	COG0395	ABC-type sugar transport system, permease component
RUMAL_RS02385	COG0058	SHG alpha-glucan phosphorylase activity
RUMAL_RS02395	COG2894	cell division
RUMAL_RS02400	COG1803	Methylglyoxal synthase
RUMAL_RS02410	COG0124	histidyl-tRNA synthetase
RUMAL_RS02425	COG1187	pseudouridine synthase activity
RUMAL_RS02430	COG3842	ATPase activity
RUMAL_RS02465	COG1609	Transcriptional regulator
RUMAL_RS02475	COG4124	Belongs to the glycosyl hydrolase 26 family
RUMAL_RS02490	COG2755	lipolytic protein G-D-S-L family
RUMAL_RS02490	COG3401	FG-GAP repeat protein
RUMAL_RS02525	COG0028	Belongs to the TPP enzyme family
RUMAL_RS02535	COG0440	acetolactate synthase activity
RUMAL_RS02545	COG3706	GGDEF domain
RUMAL_RS02585	COG5297	Belongs to the glycosyl hydrolase family 6
RUMAL_RS02585	COG2273	Hydrolase Family 16
RUMAL_RS02625	COG1151	hydroxylamine reductase activity
RUMAL_RS02645	COG1309	transcriptional regulator
RUMAL_RS02665	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
RUMAL_RS02670	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
RUMAL_RS02710	COG2801	Transposase and inactivated derivatives
RUMAL_RS02745	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
RUMAL_RS02755	COG0534	Mate efflux family protein
RUMAL_RS02765	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
RUMAL_RS02775	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
RUMAL_RS02780	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
RUMAL_RS02790	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
RUMAL_RS02795	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
RUMAL_RS02800	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
RUMAL_RS02810	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
RUMAL_RS02840	COG0826	peptidase U32
RUMAL_RS02905	COG0557	exoribonuclease II activity
RUMAL_RS02945	COG0515	serine threonine protein kinase
RUMAL_RS02945	COG0457	Tetratricopeptide repeat
RUMAL_RS02960	COG5001	Diguanylate cyclase
RUMAL_RS02980	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
RUMAL_RS02980	COG2755	lipolytic protein G-D-S-L family
RUMAL_RS02990	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
RUMAL_RS03010	COG1131	(ABC) transporter
RUMAL_RS03020	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RUMAL_RS03045	COG1876	peptidase activity
RUMAL_RS03055	COG0745	RESPONSE REGULATOR receiver
RUMAL_RS03060	COG5002	protein histidine kinase activity
RUMAL_RS03065	COG0028	Belongs to the TPP enzyme family
RUMAL_RS03070	COG0569	domain protein
RUMAL_RS03080	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
RUMAL_RS03095	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
RUMAL_RS03095	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
RUMAL_RS03105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RUMAL_RS03110	COG0765	amino acid transport
RUMAL_RS03115	COG1126	abc transporter atp-binding protein
RUMAL_RS03120	COG0386	Belongs to the glutathione peroxidase family
RUMAL_RS03150	COG1132	(ABC) transporter
RUMAL_RS03155	COG1132	(ABC) transporter
RUMAL_RS03165	COG4399	Belongs to the UPF0754 family
RUMAL_RS03175	COG0511	ligase activity, forming carbon-carbon bonds
RUMAL_RS03205	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
RUMAL_RS03300	COG2815	serine threonine protein kinase
RUMAL_RS03300	COG0515	serine threonine protein kinase
RUMAL_RS03330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RUMAL_RS03355	COG0582	viral genome integration into host DNA
RUMAL_RS03400	COG0863	Belongs to the N(4) N(6)-methyltransferase family
RUMAL_RS03435	COG4974	Belongs to the 'phage' integrase family
RUMAL_RS03470	COG3039	Transposase
RUMAL_RS03535	COG0582	viral genome integration into host DNA
RUMAL_RS03550	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
RUMAL_RS03635	COG1373	ATPase (AAA superfamily
RUMAL_RS03695	COG1373	ATPase (AAA superfamily
RUMAL_RS03785	COG0583	DNA-binding transcription factor activity
RUMAL_RS03905	COG1373	ATPase (AAA superfamily
RUMAL_RS03915	COG5297	Belongs to the glycosyl hydrolase family 6
RUMAL_RS03915	COG2273	Hydrolase Family 16
RUMAL_RS03955	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
RUMAL_RS03965	COG0675	Transposase, IS605 OrfB family
RUMAL_RS04000	COG3328	transposase activity
RUMAL_RS04060	COG0667	Aldo Keto reductase
RUMAL_RS04065	COG0667	Aldo Keto reductase
RUMAL_RS04090	COG1131	(ABC) transporter
RUMAL_RS04115	COG0656	L-ascorbic acid biosynthetic process
RUMAL_RS04135	COG2197	response regulator
RUMAL_RS04145	COG1131	(ABC) transporter
RUMAL_RS04160	COG2801	Transposase and inactivated derivatives
RUMAL_RS04185	COG2226	methyltransferase
RUMAL_RS04210	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
RUMAL_RS04215	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
RUMAL_RS04220	COG2199	diguanylate cyclase activity
RUMAL_RS04225	COG0745	RESPONSE REGULATOR receiver
RUMAL_RS04250	COG2205	protein histidine kinase activity
RUMAL_RS04280	COG1484	DNA-dependent DNA replication
RUMAL_RS04285	COG4584	PFAM Integrase catalytic
RUMAL_RS04290	COG0582	viral genome integration into host DNA
RUMAL_RS04300	COG4974	Belongs to the 'phage' integrase family
RUMAL_RS04305	COG4584	PFAM Integrase catalytic
RUMAL_RS04305	COG2390	Transcriptional regulator
RUMAL_RS04315	COG1609	Transcriptional regulator
RUMAL_RS04320	COG3507	Belongs to the glycosyl hydrolase 43 family
RUMAL_RS04360	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
RUMAL_RS04365	COG1595	DNA-templated transcription, initiation
RUMAL_RS04375	COG1489	DNA binding
RUMAL_RS04410	COG4124	Belongs to the glycosyl hydrolase 26 family
RUMAL_RS04425	COG1131	(ABC) transporter
RUMAL_RS04440	COG1021	2,3-dihydroxybenzoate-AMP ligase
RUMAL_RS04445	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RUMAL_RS04445	COG2226	methyltransferase
RUMAL_RS04445	COG3433	isochorismatase activity
RUMAL_RS04460	COG1129	ABC transporter
RUMAL_RS04475	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RUMAL_RS04485	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RUMAL_RS04485	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RUMAL_RS04490	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RUMAL_RS04500	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RUMAL_RS04510	COG0318	PFAM AMP-dependent synthetase and ligase
RUMAL_RS04510	COG0300	oxidoreductase activity
RUMAL_RS04510	COG3321	synthase
RUMAL_RS04510	COG1028	Short-chain dehydrogenase reductase Sdr
RUMAL_RS04510	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RUMAL_RS04520	COG3433	isochorismatase activity
RUMAL_RS04520	COG2226	methyltransferase
RUMAL_RS04520	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RUMAL_RS04530	COG1136	(ABC) transporter
RUMAL_RS04550	COG3620	sequence-specific DNA binding
RUMAL_RS04560	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
RUMAL_RS04565	COG0037	tRNA processing
RUMAL_RS04570	COG1104	cysteine desulfurase activity
RUMAL_RS04575	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
RUMAL_RS04575	COG5297	Belongs to the glycosyl hydrolase family 6
RUMAL_RS04595	COG0534	Mate efflux family protein
RUMAL_RS04600	COG0789	Transcriptional regulator
RUMAL_RS04610	COG2309	aminopeptidase activity
RUMAL_RS04625	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
RUMAL_RS04635	COG2199	diguanylate cyclase activity
RUMAL_RS04660	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RUMAL_RS04695	COG1122	ATPase activity
RUMAL_RS04705	COG1122	ATPase activity
RUMAL_RS04710	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
RUMAL_RS04740	COG0542	response to heat
RUMAL_RS04755	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RUMAL_RS04760	COG1131	(ABC) transporter
RUMAL_RS04780	COG1254	Belongs to the acylphosphatase family
RUMAL_RS04785	COG0572	uridine kinase
RUMAL_RS04850	COG2310	stress, protein
RUMAL_RS04855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RUMAL_RS04875	COG2155	Conserved Protein
RUMAL_RS04895	COG0776	regulation of translation
RUMAL_RS04905	COG0357	Ribosomal RNA small subunit methyltransferase G
RUMAL_RS04920	COG1366	Belongs to the anti-sigma-factor antagonist family
RUMAL_RS04935	COG3546	catalase activity
RUMAL_RS04955	COG0784	Response regulator, receiver
RUMAL_RS04955	COG2198	Histidine kinase
RUMAL_RS04955	COG5002	protein histidine kinase activity
RUMAL_RS04965	COG0488	(ABC) transporter
RUMAL_RS05005	COG0525	valine-tRNA ligase activity
RUMAL_RS05010	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
RUMAL_RS05020	COG0750	zinc metalloprotease
RUMAL_RS05025	COG1660	Displays ATPase and GTPase activities
RUMAL_RS05030	COG0812	UDP-N-acetylmuramate dehydrogenase activity
RUMAL_RS05035	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
RUMAL_RS05040	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
RUMAL_RS05055	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
RUMAL_RS05060	COG0367	asparagine synthase
RUMAL_RS05070	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
RUMAL_RS05080	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
RUMAL_RS05100	COG5001	Diguanylate cyclase
RUMAL_RS05110	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
RUMAL_RS05115	COG3345	alpha-galactosidase
RUMAL_RS05120	COG0617	tRNA 3'-terminal CCA addition
RUMAL_RS05155	COG0436	Aminotransferase
RUMAL_RS05160	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
RUMAL_RS05170	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RUMAL_RS05220	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
RUMAL_RS05225	COG0494	nUDIX hydrolase
RUMAL_RS05245	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
RUMAL_RS05245	COG1918	ferrous iron import across plasma membrane
RUMAL_RS05250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RUMAL_RS05260	COG0019	diaminopimelate decarboxylase activity
RUMAL_RS05265	COG1696	Membrane protein involved in D-alanine export
RUMAL_RS05305	COG3507	Belongs to the glycosyl hydrolase 43 family
RUMAL_RS05315	COG1131	(ABC) transporter
RUMAL_RS05325	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
RUMAL_RS05330	COG3250	beta-galactosidase activity
RUMAL_RS05330	COG5297	Belongs to the glycosyl hydrolase family 6
RUMAL_RS05340	COG5001	Diguanylate cyclase
RUMAL_RS05340	COG3300	MHYT domain
RUMAL_RS05345	COG1105	Belongs to the carbohydrate kinase PfkB family
RUMAL_RS05360	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
RUMAL_RS05370	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
RUMAL_RS05390	COG2890	protein-(glutamine-N5) methyltransferase activity
RUMAL_RS05395	COG1309	transcriptional regulator
RUMAL_RS05400	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
RUMAL_RS05415	COG2217	Heavy metal translocating P-type atpase
RUMAL_RS05420	COG2217	Heavy metal translocating P-type atpase
RUMAL_RS05425	COG2226	methyltransferase
RUMAL_RS05430	COG0640	Transcriptional regulator
RUMAL_RS05440	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RUMAL_RS05455	COG1619	proteins homologs of microcin C7 resistance protein MccF
RUMAL_RS05460	COG0523	cobalamin synthesis protein
RUMAL_RS05465	COG0803	Belongs to the bacterial solute-binding protein 9 family
RUMAL_RS05465	COG3443	Belongs to the bacterial solute-binding protein 9 family
RUMAL_RS05495	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
RUMAL_RS05495	COG2755	lipolytic protein G-D-S-L family
RUMAL_RS05500	COG4733	cellulase activity
RUMAL_RS05605	COG0582	viral genome integration into host DNA
RUMAL_RS05695	COG5377	YqaJ viral recombinase family
RUMAL_RS05770	COG1518	maintenance of DNA repeat elements
RUMAL_RS05775	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
RUMAL_RS05820	COG2020	methyltransferase activity
RUMAL_RS05855	COG1131	(ABC) transporter
RUMAL_RS05885	COG0318	PFAM AMP-dependent synthetase and ligase
RUMAL_RS05915	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
RUMAL_RS05920	COG2252	PERMEase
RUMAL_RS05930	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
RUMAL_RS05975	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
RUMAL_RS05985	COG1501	Belongs to the glycosyl hydrolase 31 family
RUMAL_RS05990	COG0668	transmembrane transport
RUMAL_RS06025	COG2226	methyltransferase
RUMAL_RS06030	COG2226	methyltransferase
RUMAL_RS06040	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
RUMAL_RS06065	COG2207	Transcriptional regulator
RUMAL_RS06065	COG1917	Cupin 2, conserved barrel domain protein
RUMAL_RS06075	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
RUMAL_RS06095	COG2199	diguanylate cyclase activity
RUMAL_RS06110	COG0488	(ABC) transporter
RUMAL_RS06120	COG1074	ATP-dependent DNA helicase activity
RUMAL_RS06130	COG3039	Transposase
RUMAL_RS06145	COG0513	Belongs to the DEAD box helicase family
RUMAL_RS06195	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
RUMAL_RS06200	COG1982	Orn Lys Arg decarboxylase major
RUMAL_RS06225	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
RUMAL_RS06240	COG0010	Belongs to the arginase family
RUMAL_RS06280	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
RUMAL_RS06290	COG2199	diguanylate cyclase activity
RUMAL_RS06290	COG2202	Pas domain
RUMAL_RS06290	COG2200	EAL domain
RUMAL_RS06320	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
RUMAL_RS06335	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RUMAL_RS06360	COG0791	NLP P60 protein
RUMAL_RS06360	COG3883	PFAM NLP P60 protein
RUMAL_RS06365	COG2385	sporulation resulting in formation of a cellular spore
RUMAL_RS06370	COG0673	inositol 2-dehydrogenase activity
RUMAL_RS06395	COG0590	tRNA wobble adenosine to inosine editing
RUMAL_RS06405	COG3401	FG-GAP repeat protein
RUMAL_RS06410	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
RUMAL_RS06415	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
RUMAL_RS06420	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
RUMAL_RS06425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RUMAL_RS06440	COG0697	spore germination
RUMAL_RS06450	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
RUMAL_RS06480	COG0037	tRNA processing
RUMAL_RS06490	COG0546	phosphoglycolate phosphatase activity
RUMAL_RS06495	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RUMAL_RS06525	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RUMAL_RS06530	COG1609	Transcriptional regulator
RUMAL_RS06535	COG2200	EAL domain
RUMAL_RS06535	COG3287	FIST C domain
RUMAL_RS06535	COG2199	diguanylate cyclase activity
RUMAL_RS06550	COG0656	L-ascorbic acid biosynthetic process
RUMAL_RS06555	COG1748	Saccharopine dehydrogenase
RUMAL_RS06640	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
RUMAL_RS06700	COG0716	FMN binding
RUMAL_RS06775	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
RUMAL_RS06795	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
RUMAL_RS06795	COG0028	Belongs to the TPP enzyme family
RUMAL_RS06805	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
RUMAL_RS06810	COG1716	ATPase activity
RUMAL_RS06810	COG1131	(ABC) transporter
RUMAL_RS06810	COG0842	Transport permease protein
RUMAL_RS06820	COG4868	Belongs to the UPF0371 family
RUMAL_RS06875	COG4974	Belongs to the 'phage' integrase family
RUMAL_RS06880	COG3328	transposase activity
RUMAL_RS06965	COG4124	Belongs to the glycosyl hydrolase 26 family
RUMAL_RS06985	COG2210	Belongs to the sulfur carrier protein TusA family
RUMAL_RS06995	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
RUMAL_RS07060	COG0270	DNA (cytosine-5-)-methyltransferase activity
RUMAL_RS07100	COG2088	sporulation resulting in formation of a cellular spore
RUMAL_RS07195	COG1121	(ABC) transporter
RUMAL_RS07275	COG1131	(ABC) transporter
RUMAL_RS07305	COG1132	(ABC) transporter
RUMAL_RS07320	COG1136	(ABC) transporter
RUMAL_RS07320	COG0577	efflux transmembrane transporter activity
RUMAL_RS07335	COG0542	response to heat
RUMAL_RS07420	COG0446	pyridine nucleotide-disulphide oxidoreductase
RUMAL_RS07425	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RUMAL_RS07435	COG1609	Transcriptional regulator
RUMAL_RS07530	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
RUMAL_RS07575	COG0504	CTP synthase activity
RUMAL_RS07580	COG0436	Aminotransferase
RUMAL_RS07590	COG0493	'glutamate synthase
RUMAL_RS07625	COG2199	diguanylate cyclase activity
RUMAL_RS07625	COG2203	Gaf domain
RUMAL_RS07640	COG2273	Hydrolase Family 16
RUMAL_RS07645	COG2207	Transcriptional regulator
RUMAL_RS07665	COG0745	RESPONSE REGULATOR receiver
RUMAL_RS07695	COG0254	rRNA binding
RUMAL_RS07700	COG1739	Uncharacterized protein family UPF0029
RUMAL_RS07705	COG0232	Belongs to the dGTPase family. Type 2 subfamily
RUMAL_RS07710	COG0358	DNA primase activity
RUMAL_RS07715	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
RUMAL_RS07720	COG1959	2 iron, 2 sulfur cluster binding
RUMAL_RS07745	COG0367	asparagine synthase
RUMAL_RS07775	COG0714	Associated with various cellular activities
RUMAL_RS07785	COG3552	Protein containing von Willebrand factor type A (VWA) domain
RUMAL_RS07805	COG1136	(ABC) transporter
RUMAL_RS07820	COG2201	protein-glutamate methylesterase activity
RUMAL_RS07855	COG0745	RESPONSE REGULATOR receiver
RUMAL_RS07860	COG5002	protein histidine kinase activity
RUMAL_RS07885	COG0515	serine threonine protein kinase
RUMAL_RS07885	COG2815	serine threonine protein kinase
RUMAL_RS07905	COG0655	NAD(P)H dehydrogenase (quinone) activity
RUMAL_RS07970	COG3655	Transcriptional regulator
RUMAL_RS07995	COG3345	alpha-galactosidase
RUMAL_RS08000	COG4977	sequence-specific DNA binding
RUMAL_RS08000	COG1917	Cupin 2, conserved barrel domain protein
RUMAL_RS08020	COG0671	phosphoesterase, PA-phosphatase related
RUMAL_RS08030	COG2199	diguanylate cyclase activity
RUMAL_RS08030	COG3287	FIST C domain
RUMAL_RS08030	COG2200	EAL domain
RUMAL_RS08040	COG0667	Aldo Keto reductase
RUMAL_RS08070	COG0110	maltose O-acetyltransferase activity
RUMAL_RS08100	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
RUMAL_RS08110	COG3956	TIGRFAM MazG family protein
RUMAL_RS08135	COG1854	S-ribosylhomocysteine lyase activity
RUMAL_RS08165	COG2199	diguanylate cyclase activity
RUMAL_RS08175	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
RUMAL_RS08190	COG3655	Transcriptional regulator
RUMAL_RS08200	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
RUMAL_RS08215	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
RUMAL_RS08225	COG0745	RESPONSE REGULATOR receiver
RUMAL_RS08240	COG1979	alcohol dehydrogenase
RUMAL_RS08265	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RUMAL_RS08265	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RUMAL_RS08275	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
RUMAL_RS08290	COG3708	Transcriptional regulator
RUMAL_RS08290	COG2207	Transcriptional regulator
RUMAL_RS08300	COG0726	polysaccharide deacetylase
RUMAL_RS08300	COG1649	PFAM Uncharacterised BCR, COG1649
RUMAL_RS08310	COG0205	6-phosphofructokinase activity
RUMAL_RS08315	COG2195	Cleaves the N-terminal amino acid of tripeptides
RUMAL_RS08320	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
RUMAL_RS08350	COG1408	metallophosphoesterase
RUMAL_RS08355	COG0210	DNA helicase
RUMAL_RS08370	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
RUMAL_RS08375	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
RUMAL_RS08380	COG0359	binds to the 23S rRNA
RUMAL_RS08385	COG0305	Participates in initiation and elongation during chromosome replication
RUMAL_RS08390	COG0037	tRNA processing
RUMAL_RS08395	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RUMAL_RS08400	COG1692	metallophosphoesterase
RUMAL_RS08405	COG2359	stage V sporulation protein S
RUMAL_RS08410	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
RUMAL_RS08415	COG1323	Belongs to the UPF0348 family
RUMAL_RS08420	COG3830	Belongs to the UPF0237 family
RUMAL_RS08425	COG2848	UPF0210 protein
RUMAL_RS08435	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
RUMAL_RS08440	COG1191	sigma factor activity
RUMAL_RS08445	COG1873	PFAM PRC-barrel domain
RUMAL_RS08450	COG0052	Belongs to the universal ribosomal protein uS2 family
RUMAL_RS08465	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
RUMAL_RS08465	COG0758	DNA mediated transformation
RUMAL_RS08490	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
RUMAL_RS08490	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
RUMAL_RS08495	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
RUMAL_RS08500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RUMAL_RS08505	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RUMAL_RS08580	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
RUMAL_RS08585	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
RUMAL_RS08605	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
RUMAL_RS08625	COG0714	Associated with various cellular activities
RUMAL_RS08665	COG2304	oxidoreductase activity
RUMAL_RS08685	COG0328	RNA-DNA hybrid ribonuclease activity
RUMAL_RS08695	COG0482	sulfurtransferase activity
RUMAL_RS08705	COG0159	tryptophan synthase activity
RUMAL_RS08710	COG0133	tryptophan synthase activity
RUMAL_RS08715	COG1605	Chorismate mutase
RUMAL_RS08715	COG0077	Prephenate dehydratase
RUMAL_RS08720	COG0134	indole-3-glycerol-phosphate synthase activity
RUMAL_RS08725	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
RUMAL_RS08725	COG0512	Glutamine amidotransferase of anthranilate synthase
RUMAL_RS08735	COG0596	Alpha beta hydrolase
RUMAL_RS08780	COG0628	permease
RUMAL_RS08825	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
RUMAL_RS08845	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
RUMAL_RS08860	COG1522	sequence-specific DNA binding
RUMAL_RS08865	COG0436	Aminotransferase
RUMAL_RS08890	COG1418	mRNA catabolic process
RUMAL_RS08910	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RUMAL_RS08930	COG0534	Mate efflux family protein
RUMAL_RS08940	COG2153	protein acetylation
RUMAL_RS08955	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
RUMAL_RS08960	COG2226	methyltransferase
RUMAL_RS08970	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
RUMAL_RS08980	COG1968	undecaprenyl-diphosphatase activity
RUMAL_RS08985	COG1674	ftsk spoiiie
RUMAL_RS08990	COG2333	competence protein COMEC
RUMAL_RS08990	COG0658	competence protein
RUMAL_RS09000	COG1737	Transcriptional regulator
RUMAL_RS09005	COG2081	HI0933 family
RUMAL_RS09010	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
RUMAL_RS09015	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
RUMAL_RS09015	COG0539	negative regulation of cytoplasmic translation
RUMAL_RS09020	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RUMAL_RS09025	COG0116	Belongs to the methyltransferase superfamily
RUMAL_RS09035	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RUMAL_RS09080	COG1393	Belongs to the ArsC family
RUMAL_RS09100	COG1234	tRNA 3'-trailer cleavage
RUMAL_RS09105	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
RUMAL_RS09125	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
RUMAL_RS09150	COG1472	Belongs to the glycosyl hydrolase 3 family
RUMAL_RS09160	COG1671	Belongs to the UPF0178 family
RUMAL_RS09170	COG0546	phosphoglycolate phosphatase activity
RUMAL_RS09175	COG1561	YicC-like family, N-terminal region
RUMAL_RS09180	COG2052	Domain of unknown function (DUF370)
RUMAL_RS09185	COG0194	GDP metabolic process
RUMAL_RS09190	COG1758	RNA polymerase activity
RUMAL_RS09195	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
RUMAL_RS09200	COG0242	peptide deformylase activity
RUMAL_RS09205	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
RUMAL_RS09210	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RUMAL_RS09210	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
RUMAL_RS09215	COG0820	rRNA (adenine-C2-)-methyltransferase activity
RUMAL_RS09220	COG0631	protein serine/threonine phosphatase activity
RUMAL_RS09225	COG0515	serine threonine protein kinase
RUMAL_RS09225	COG2815	serine threonine protein kinase
RUMAL_RS09230	COG1162	GTPase activity
RUMAL_RS09240	COG3833	ABC-type maltose transport systems, permease component
RUMAL_RS09245	COG1175	transmembrane transport
RUMAL_RS09250	COG2182	Extracellular solute-binding protein
RUMAL_RS09270	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
RUMAL_RS09280	COG1193	negative regulation of DNA recombination
RUMAL_RS09290	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
RUMAL_RS09295	COG0454	-acetyltransferase
RUMAL_RS09300	COG0494	nUDIX hydrolase
RUMAL_RS09345	COG1609	Transcriptional regulator
RUMAL_RS09380	COG0297	glycogen (starch) synthase activity
RUMAL_RS09395	COG0602	queuosine metabolic process
RUMAL_RS09405	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
RUMAL_RS09405	COG1328	CTP reductase activity
RUMAL_RS09415	COG0540	Belongs to the ATCase OTCase family
RUMAL_RS09420	COG0860	N-Acetylmuramoyl-L-alanine amidase
RUMAL_RS09435	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
RUMAL_RS09465	COG1247	-acetyltransferase
RUMAL_RS09475	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
RUMAL_RS09480	COG2011	ABC-type metal ion transport system permease component
RUMAL_RS09485	COG1464	Belongs to the NlpA lipoprotein family
RUMAL_RS09490	COG0367	asparagine synthase
RUMAL_RS09495	COG1328	CTP reductase activity
RUMAL_RS09510	COG0708	Exodeoxyribonuclease III
RUMAL_RS09520	COG0017	Asparaginyl-tRNA synthetase
RUMAL_RS09530	COG1476	TRANSCRIPTIONal
RUMAL_RS09550	COG5002	protein histidine kinase activity
RUMAL_RS09555	COG1283	sodium-dependent phosphate transmembrane transporter activity
RUMAL_RS09560	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RUMAL_RS09570	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
RUMAL_RS09575	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
RUMAL_RS09580	COG0537	adenosine 5'-monophosphoramidase activity
RUMAL_RS09595	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
RUMAL_RS09675	COG0454	-acetyltransferase
RUMAL_RS09700	COG1609	Transcriptional regulator
RUMAL_RS09705	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
RUMAL_RS09705	COG4797	methyltransferase
RUMAL_RS09710	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
RUMAL_RS09715	COG3328	transposase activity
RUMAL_RS09720	COG1028	Short-chain dehydrogenase reductase Sdr
RUMAL_RS09735	COG0745	RESPONSE REGULATOR receiver
RUMAL_RS09740	COG2205	protein histidine kinase activity
RUMAL_RS09740	COG3292	Two component regulator propeller
RUMAL_RS09740	COG0745	RESPONSE REGULATOR receiver
RUMAL_RS09745	COG1418	mRNA catabolic process
RUMAL_RS09750	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
RUMAL_RS09755	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
RUMAL_RS09755	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
RUMAL_RS09760	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
RUMAL_RS09770	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RUMAL_RS09775	COG1024	Enoyl-CoA hydratase
RUMAL_RS09800	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
RUMAL_RS09815	COG0318	PFAM AMP-dependent synthetase and ligase
RUMAL_RS09820	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RUMAL_RS09830	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RUMAL_RS09855	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
RUMAL_RS09860	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
RUMAL_RS09865	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RUMAL_RS09875	COG3507	Belongs to the glycosyl hydrolase 43 family
RUMAL_RS09890	COG1609	Transcriptional regulator
RUMAL_RS09905	COG0826	peptidase U32
RUMAL_RS09910	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
RUMAL_RS09915	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
RUMAL_RS09930	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
RUMAL_RS09940	COG0497	DNA recombination
RUMAL_RS09945	COG1438	arginine binding
RUMAL_RS09950	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
RUMAL_RS09955	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
RUMAL_RS09960	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
RUMAL_RS09965	COG0142	geranyltranstransferase activity
RUMAL_RS09970	COG1722	exodeoxyribonuclease VII activity
RUMAL_RS09975	COG1570	exodeoxyribonuclease VII activity
RUMAL_RS09980	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
RUMAL_RS09985	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RUMAL_RS10055	COG3958	Transketolase
RUMAL_RS10060	COG3959	Transketolase, thiamine diphosphate binding domain
RUMAL_RS10070	COG0564	pseudouridine synthase activity
RUMAL_RS10075	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
RUMAL_RS10090	COG1799	cell septum assembly
RUMAL_RS10095	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
RUMAL_RS10105	COG1923	regulation of RNA biosynthetic process
RUMAL_RS10110	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
RUMAL_RS10120	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
RUMAL_RS10130	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RUMAL_RS10160	COG0493	'glutamate synthase
RUMAL_RS10180	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RUMAL_RS10205	COG2339	peptidase activity
RUMAL_RS10240	COG1489	DNA binding
RUMAL_RS10285	COG1136	(ABC) transporter
RUMAL_RS10310	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RUMAL_RS10315	COG1132	(ABC) transporter
RUMAL_RS10320	COG2375	cellular response to nickel ion
RUMAL_RS10320	COG1132	(ABC) transporter
RUMAL_RS10350	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
RUMAL_RS10355	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RUMAL_RS10380	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
RUMAL_RS10415	COG1304	FMN binding
RUMAL_RS10425	COG4974	Belongs to the 'phage' integrase family
RUMAL_RS10455	COG4124	Belongs to the glycosyl hydrolase 26 family
RUMAL_RS10475	COG0137	argininosuccinate synthase activity
RUMAL_RS10485	COG0165	Argininosuccinate lyase
RUMAL_RS10495	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
RUMAL_RS10500	COG1472	Belongs to the glycosyl hydrolase 3 family
RUMAL_RS10505	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
RUMAL_RS10520	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
RUMAL_RS10535	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
RUMAL_RS10545	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
RUMAL_RS10555	COG0527	aspartate kinase activity
RUMAL_RS10610	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
RUMAL_RS10615	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RUMAL_RS10695	COG0107	imidazoleglycerol-phosphate synthase activity
RUMAL_RS10715	COG0131	Imidazoleglycerol-phosphate dehydratase
RUMAL_RS10725	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
RUMAL_RS10730	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
RUMAL_RS10735	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
RUMAL_RS10750	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
RUMAL_RS10755	COG0750	zinc metalloprotease
RUMAL_RS10765	COG4589	Belongs to the CDS family
RUMAL_RS10775	COG0233	cytoplasmic translational termination
RUMAL_RS10780	COG0528	UMP kinase activity
RUMAL_RS10785	COG0432	Pfam Uncharacterised protein family UPF0047
RUMAL_RS10790	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
RUMAL_RS10800	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
RUMAL_RS10805	COG1160	GTP binding
RUMAL_RS10810	COG0333	Belongs to the bacterial ribosomal protein bL32 family
RUMAL_RS10835	COG3706	GGDEF domain
RUMAL_RS10835	COG4251	negative regulation of phosphorylation
RUMAL_RS10835	COG5001	Diguanylate cyclase
RUMAL_RS10835	COG2203	Gaf domain
RUMAL_RS10855	COG1136	(ABC) transporter
RUMAL_RS10865	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
RUMAL_RS10870	COG0719	Fe-S assembly protein
RUMAL_RS10880	COG1205	dead DEAH box helicase
RUMAL_RS10880	COG1111	helicase
RUMAL_RS10915	COG5433	transposase activity
RUMAL_RS10925	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
RUMAL_RS10930	COG2022	thiamine diphosphate biosynthetic process
RUMAL_RS10940	COG0352	thiamine-phosphate diphosphorylase activity
RUMAL_RS10950	COG0351	phosphomethylpyrimidine kinase
RUMAL_RS10950	COG0352	thiamine-phosphate diphosphorylase activity
RUMAL_RS10955	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
RUMAL_RS10975	COG1131	(ABC) transporter
RUMAL_RS10990	COG1690	Belongs to the RtcB family
RUMAL_RS11005	COG2205	protein histidine kinase activity
RUMAL_RS11010	COG0745	RESPONSE REGULATOR receiver
RUMAL_RS11020	COG1904	glucuronate isomerase
RUMAL_RS11025	COG2721	sulfolactate sulfo-lyase activity
RUMAL_RS11030	COG0246	Mannitol dehydrogenase
RUMAL_RS11035	COG3842	ATPase activity
RUMAL_RS11040	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
RUMAL_RS11055	COG0800	Aldolase
RUMAL_RS11060	COG1028	Short-chain dehydrogenase reductase Sdr
RUMAL_RS11070	COG1486	melibiose metabolic process
RUMAL_RS11075	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
RUMAL_RS11095	COG3842	ATPase activity
RUMAL_RS11115	COG0395	ABC-type sugar transport system, permease component
RUMAL_RS11120	COG4209	transmembrane transport
RUMAL_RS11130	COG0493	'glutamate synthase
RUMAL_RS11135	COG2207	Transcriptional regulator
RUMAL_RS11135	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RUMAL_RS11160	COG0215	cysteine-tRNA ligase activity
RUMAL_RS11170	COG1045	serine acetyltransferase
RUMAL_RS11175	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
RUMAL_RS11180	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RUMAL_RS11195	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
RUMAL_RS11210	COG2890	protein-(glutamine-N5) methyltransferase activity
RUMAL_RS11215	COG3872	metal-dependent enzyme
RUMAL_RS11220	COG5002	protein histidine kinase activity
RUMAL_RS11225	COG0745	RESPONSE REGULATOR receiver
RUMAL_RS11240	COG0698	ribose 5-phosphate isomerase
RUMAL_RS11245	COG1214	PFAM Peptidase M22, glycoprotease
RUMAL_RS11250	COG0802	atpase or kinase
RUMAL_RS11260	COG2759	Belongs to the formate--tetrahydrofolate ligase family
RUMAL_RS11270	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RUMAL_RS11285	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
RUMAL_RS11305	COG0714	Associated with various cellular activities
RUMAL_RS11310	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
RUMAL_RS11320	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
RUMAL_RS11340	COG5001	Diguanylate cyclase
RUMAL_RS11340	COG3706	GGDEF domain
RUMAL_RS11340	COG2203	Gaf domain
RUMAL_RS11340	COG4251	negative regulation of phosphorylation
RUMAL_RS11345	COG2199	diguanylate cyclase activity
RUMAL_RS11345	COG2203	Gaf domain
RUMAL_RS11360	COG0577	efflux transmembrane transporter activity
RUMAL_RS11365	COG1136	(ABC) transporter
RUMAL_RS11380	COG5002	protein histidine kinase activity
RUMAL_RS11385	COG0745	RESPONSE REGULATOR receiver
RUMAL_RS11390	COG3976	FMN-binding domain protein
RUMAL_RS11390	COG1053	succinate dehydrogenase
RUMAL_RS11395	COG1136	(ABC) transporter
RUMAL_RS11395	COG0577	efflux transmembrane transporter activity
RUMAL_RS11585	COG1132	(ABC) transporter
RUMAL_RS11590	COG1132	(ABC) transporter
RUMAL_RS11595	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
RUMAL_RS11640	COG2910	NAD(P)H-binding
RUMAL_RS11645	COG1959	2 iron, 2 sulfur cluster binding
RUMAL_RS11665	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
RUMAL_RS11765	COG1619	proteins homologs of microcin C7 resistance protein MccF
RUMAL_RS11770	COG0494	nUDIX hydrolase
RUMAL_RS11795	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
RUMAL_RS11805	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
RUMAL_RS11820	COG0211	Belongs to the bacterial ribosomal protein bL27 family
RUMAL_RS11830	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
RUMAL_RS11835	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
RUMAL_RS11840	COG0217	transcriptional regulatory protein
RUMAL_RS11845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RUMAL_RS11855	COG1253	flavin adenine dinucleotide binding
RUMAL_RS11870	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RUMAL_RS11875	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
RUMAL_RS11885	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
RUMAL_RS11955	COG1358	cellular component organization or biogenesis
RUMAL_RS11965	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
RUMAL_RS11970	COG2310	stress, protein
RUMAL_RS11980	COG3853	Toxic anion resistance protein (TelA)
RUMAL_RS11990	COG0726	polysaccharide deacetylase
RUMAL_RS12000	COG0072	phenylalanine-tRNA ligase activity
RUMAL_RS12000	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RUMAL_RS12005	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
RUMAL_RS12010	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
RUMAL_RS12030	COG1164	Oligoendopeptidase f
RUMAL_RS12045	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
RUMAL_RS12060	COG3706	GGDEF domain
RUMAL_RS12075	COG0187	DNA topoisomerase II activity
RUMAL_RS12100	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
RUMAL_RS12135	COG1459	type II secretion system
RUMAL_RS12145	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
RUMAL_RS12170	COG1126	abc transporter atp-binding protein
RUMAL_RS12175	COG0765	amino acid transport
RUMAL_RS12180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RUMAL_RS12185	COG2197	response regulator
RUMAL_RS12200	COG1181	Belongs to the D-alanine--D-alanine ligase family
RUMAL_RS12205	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
RUMAL_RS12215	COG0018	arginyl-trna synthetase
RUMAL_RS12225	COG0622	Phosphoesterase
RUMAL_RS12235	COG1940	carbohydrate kinase activity
RUMAL_RS12240	COG4443	Transcriptional Coactivator p15 (PC4)
RUMAL_RS12250	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
RUMAL_RS12260	COG1461	Dihydroxyacetone kinase
RUMAL_RS12270	COG0396	ATPase activity
RUMAL_RS12285	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
RUMAL_RS12290	COG0822	iron-sulfur transferase activity
RUMAL_RS12305	COG1959	2 iron, 2 sulfur cluster binding
RUMAL_RS12310	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
RUMAL_RS12320	COG1433	Dinitrogenase iron-molybdenum cofactor
RUMAL_RS12320	COG0535	radical SAM domain protein
RUMAL_RS12325	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
RUMAL_RS12340	COG0535	radical SAM domain protein
RUMAL_RS12340	COG1433	Dinitrogenase iron-molybdenum cofactor
RUMAL_RS12350	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RUMAL_RS12355	COG0626	cystathionine gamma-synthase activity
RUMAL_RS12360	COG1609	Transcriptional regulator
RUMAL_RS12375	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
RUMAL_RS12390	COG4733	cellulase activity
RUMAL_RS12395	COG3300	MHYT domain
RUMAL_RS12395	COG5001	Diguanylate cyclase
RUMAL_RS12405	COG4989	oxidoreductase activity
RUMAL_RS12410	COG0534	Mate efflux family protein
RUMAL_RS12440	COG0583	DNA-binding transcription factor activity
RUMAL_RS12450	COG1136	(ABC) transporter
RUMAL_RS12450	COG0577	efflux transmembrane transporter activity
RUMAL_RS12455	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
RUMAL_RS12465	COG0322	excinuclease ABC activity
RUMAL_RS12470	COG0242	peptide deformylase activity
RUMAL_RS12500	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
RUMAL_RS12515	COG4496	protein, YerC YecD
RUMAL_RS12545	COG0218	Necessary for normal cell division and for the maintenance of normal septation
RUMAL_RS12555	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
RUMAL_RS12560	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
RUMAL_RS12565	COG0629	single-stranded DNA binding
RUMAL_RS12570	COG0360	Binds together with S18 to 16S ribosomal RNA
RUMAL_RS12580	COG1316	TRANSCRIPTIONal
RUMAL_RS12585	COG1216	Glycosyl transferase, family 2
RUMAL_RS12590	COG2815	serine threonine protein kinase
RUMAL_RS12590	COG0515	serine threonine protein kinase
RUMAL_RS12615	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
RUMAL_RS12620	COG0784	Response regulator, receiver
RUMAL_RS12620	COG2205	protein histidine kinase activity
RUMAL_RS12630	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
RUMAL_RS12635	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
RUMAL_RS12645	COG4974	Belongs to the 'phage' integrase family
RUMAL_RS12765	COG4584	PFAM Integrase catalytic
RUMAL_RS12765	COG2390	Transcriptional regulator
RUMAL_RS12785	COG4974	Belongs to the 'phage' integrase family
RUMAL_RS12830	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
RUMAL_RS12835	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
RUMAL_RS12840	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
RUMAL_RS12860	COG3401	FG-GAP repeat protein
RUMAL_RS12875	COG1045	serine acetyltransferase
RUMAL_RS12935	COG0012	GTP binding
RUMAL_RS12950	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
RUMAL_RS12950	COG0116	Belongs to the methyltransferase superfamily
RUMAL_RS12960	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
RUMAL_RS12990	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
RUMAL_RS13010	COG2255	four-way junction helicase activity
RUMAL_RS13025	COG0632	four-way junction helicase activity
RUMAL_RS13035	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
RUMAL_RS13040	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
RUMAL_RS13045	COG1773	rubredoxin
RUMAL_RS13075	COG0081	regulation of translation
RUMAL_RS13080	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
RUMAL_RS13085	COG0250	Participates in transcription elongation, termination and antitermination
RUMAL_RS13090	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
RUMAL_RS13100	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RUMAL_RS13105	COG1316	TRANSCRIPTIONal
RUMAL_RS13110	COG0300	oxidoreductase activity
RUMAL_RS13120	COG0420	3'-5' exonuclease activity
RUMAL_RS13125	COG0419	ATPase involved in DNA repair
RUMAL_RS13130	COG2002	toxin-antitoxin pair type II binding
RUMAL_RS13135	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
RUMAL_RS13155	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
RUMAL_RS13160	COG2873	o-acetylhomoserine
RUMAL_RS13175	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
RUMAL_RS13240	COG1131	(ABC) transporter
RUMAL_RS13245	COG5297	Belongs to the glycosyl hydrolase family 6
RUMAL_RS13300	COG2183	response to ionizing radiation
RUMAL_RS13345	COG1385	rRNA (uridine-N3-)-methyltransferase activity
RUMAL_RS13385	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
RUMAL_RS13390	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RUMAL_RS13400	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
RUMAL_RS13445	COG1136	(ABC) transporter
RUMAL_RS13450	COG0745	RESPONSE REGULATOR receiver
RUMAL_RS13470	COG0395	ABC-type sugar transport system, permease component
RUMAL_RS13475	COG4209	transmembrane transport
RUMAL_RS13485	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
RUMAL_RS13505	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
RUMAL_RS13525	COG1185	polyribonucleotide nucleotidyltransferase activity
RUMAL_RS13530	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
RUMAL_RS13540	COG1686	Belongs to the peptidase S11 family
RUMAL_RS13545	COG0542	response to heat
RUMAL_RS13550	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
RUMAL_RS13565	COG2873	o-acetylhomoserine
RUMAL_RS13570	COG0583	DNA-binding transcription factor activity
RUMAL_RS13580	COG0673	inositol 2-dehydrogenase activity
RUMAL_RS13585	COG5002	protein histidine kinase activity
RUMAL_RS13585	COG0784	Response regulator, receiver
RUMAL_RS13590	COG2337	Toxic component of a toxin-antitoxin (TA) module
RUMAL_RS13600	COG0582	viral genome integration into host DNA
RUMAL_RS13725	COG0582	viral genome integration into host DNA
RUMAL_RS13795	COG0582	viral genome integration into host DNA
RUMAL_RS13910	COG1335	isochorismatase
RUMAL_RS13930	COG3867	Arabinogalactan endo-beta-1,4-galactanase
RUMAL_RS13970	COG2177	Part of the ABC transporter FtsEX involved in
RUMAL_RS13975	COG2884	Cell division ATP-binding protein ftsE
RUMAL_RS13980	COG3835	regulator
RUMAL_RS13990	COG0336	Belongs to the RNA methyltransferase TrmD family
RUMAL_RS13995	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
RUMAL_RS14005	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
RUMAL_RS14005	COG2755	lipolytic protein G-D-S-L family
RUMAL_RS14025	COG3870	Protein conserved in bacteria
RUMAL_RS14070	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
RUMAL_RS14100	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
RUMAL_RS14125	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
RUMAL_RS14130	COG3250	beta-galactosidase activity
RUMAL_RS14145	COG0058	SHG alpha-glucan phosphorylase activity
RUMAL_RS14170	COG0561	phosphatase activity
RUMAL_RS14175	COG1368	sulfuric ester hydrolase activity
RUMAL_RS14180	COG0227	Belongs to the bacterial ribosomal protein bL28 family
RUMAL_RS14190	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
RUMAL_RS14195	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
RUMAL_RS14205	COG3874	Sporulation protein YtfJ
RUMAL_RS14210	COG1686	Belongs to the peptidase S11 family
RUMAL_RS14220	COG1187	pseudouridine synthase activity
RUMAL_RS14230	COG0659	secondary active sulfate transmembrane transporter activity
RUMAL_RS14275	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
RUMAL_RS14275	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
RUMAL_RS14295	COG2201	protein-glutamate methylesterase activity
RUMAL_RS14320	COG1472	Belongs to the glycosyl hydrolase 3 family
RUMAL_RS14330	COG2816	NAD+ diphosphatase activity
RUMAL_RS14340	COG0463	Glycosyl transferase, family 2
RUMAL_RS14345	COG0084	hydrolase, TatD family'
RUMAL_RS14410	COG0148	phosphopyruvate hydratase activity
RUMAL_RS14500	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
RUMAL_RS14505	COG1070	Carbohydrate kinase
RUMAL_RS14530	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RUMAL_RS14530	COG1773	rubredoxin
RUMAL_RS14555	COG1482	cell wall glycoprotein biosynthetic process
RUMAL_RS14565	COG1940	carbohydrate kinase activity
RUMAL_RS14580	COG0129	dihydroxy-acid dehydratase activity
RUMAL_RS14590	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
RUMAL_RS14600	COG0778	Nitroreductase
RUMAL_RS14600	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
RUMAL_RS14610	COG0284	orotidine-5'-phosphate decarboxylase activity
RUMAL_RS14630	COG0543	2 iron, 2 sulfur cluster binding
RUMAL_RS14635	COG0167	dihydroorotate dehydrogenase activity
RUMAL_RS14650	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
RUMAL_RS14660	COG2205	protein histidine kinase activity
RUMAL_RS14745	COG0318	PFAM AMP-dependent synthetase and ligase
RUMAL_RS14750	COG1472	Belongs to the glycosyl hydrolase 3 family
RUMAL_RS14775	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
RUMAL_RS14780	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
RUMAL_RS14785	COG0049	tRNA binding
RUMAL_RS14790	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
RUMAL_RS14810	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
RUMAL_RS14815	COG0085	RNA polymerase activity
RUMAL_RS14825	COG0606	chelatase, subunit chli
RUMAL_RS14840	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
RUMAL_RS14870	COG3843	relaxase mobilization nuclease domain protein
RUMAL_RS14915	COG2873	o-acetylhomoserine
RUMAL_RS14925	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
RUMAL_RS14930	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
RUMAL_RS14955	COG3534	alpha-L-arabinofuranosidase
RUMAL_RS14965	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
RUMAL_RS14975	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
RUMAL_RS14995	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
RUMAL_RS15000	COG0514	ATP-dependent DNA helicase (RecQ)
RUMAL_RS15005	COG2323	membrane
RUMAL_RS15020	COG1876	peptidase activity
RUMAL_RS15025	COG1605	Chorismate mutase
RUMAL_RS15025	COG0077	Prephenate dehydratase
RUMAL_RS15030	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
RUMAL_RS15075	COG1490	D-aminoacyl-tRNA deacylase activity
RUMAL_RS15090	COG2003	Belongs to the UPF0758 family
RUMAL_RS15095	COG0626	cystathionine gamma-synthase activity
RUMAL_RS15110	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
RUMAL_RS15165	COG0596	Alpha beta hydrolase
RUMAL_RS15180	COG3475	LICD family
RUMAL_RS15230	COG0714	Associated with various cellular activities
RUMAL_RS15265	COG0779	Required for maturation of 30S ribosomal subunits
RUMAL_RS15270	COG0195	Participates in both transcription termination and antitermination
RUMAL_RS15275	COG2740	Nucleic-acid-binding protein implicated in transcription termination
RUMAL_RS15300	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
RUMAL_RS15310	COG0196	riboflavin kinase activity
RUMAL_RS15380	COG1773	rubredoxin
RUMAL_RS15380	COG1592	Rubrerythrin
RUMAL_RS15385	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
RUMAL_RS15400	COG0251	oxidation-reduction process
RUMAL_RS15410	COG0475	glutathione-regulated potassium exporter activity
RUMAL_RS15415	COG1418	mRNA catabolic process
RUMAL_RS15430	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
RUMAL_RS15440	COG2001	Belongs to the MraZ family
RUMAL_RS15445	COG0275	rRNA processing
RUMAL_RS15455	COG0768	penicillin binding
RUMAL_RS15460	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
RUMAL_RS15465	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
RUMAL_RS15470	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
RUMAL_RS15475	COG0772	Belongs to the SEDS family
RUMAL_RS15480	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
RUMAL_RS15490	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
RUMAL_RS15495	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
RUMAL_RS15525	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RUMAL_RS15540	COG1774	PSP1 C-terminal conserved region
RUMAL_RS15560	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
RUMAL_RS15585	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
RUMAL_RS15590	COG0291	Belongs to the bacterial ribosomal protein bL35 family
RUMAL_RS15600	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RUMAL_RS15610	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
RUMAL_RS15620	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
RUMAL_RS15650	COG0571	ribonuclease III activity
RUMAL_RS15680	COG0552	protein localization to endoplasmic reticulum
RUMAL_RS15695	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
RUMAL_RS15700	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
RUMAL_RS15700	COG1713	HD superfamily hydrolase involved in NAD metabolism
RUMAL_RS15705	COG0799	negative regulation of ribosome biogenesis
RUMAL_RS15710	COG0495	leucyl-tRNA aminoacylation
RUMAL_RS15725	COG0828	Belongs to the bacterial ribosomal protein bS21 family
RUMAL_RS15735	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
RUMAL_RS15755	COG0647	UMP catabolic process
RUMAL_RS15765	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
RUMAL_RS15765	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
RUMAL_RS15780	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
RUMAL_RS15805	COG0538	isocitrate dehydrogenase activity
RUMAL_RS15815	COG1454	alcohol dehydrogenase
RUMAL_RS15820	COG1609	Transcriptional regulator
RUMAL_RS15830	COG0157	Belongs to the NadC ModD family
RUMAL_RS15845	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
RUMAL_RS15870	COG0193	aminoacyl-tRNA hydrolase activity
RUMAL_RS15875	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
RUMAL_RS15895	COG0494	nUDIX hydrolase
RUMAL_RS15905	COG1115	amino acid carrier protein
RUMAL_RS15910	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
RUMAL_RS15915	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
RUMAL_RS15930	COG2070	2-Nitropropane dioxygenase
RUMAL_RS15940	COG1028	Short-chain dehydrogenase reductase Sdr
RUMAL_RS15945	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
RUMAL_RS15965	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
RUMAL_RS15970	COG0439	Biotin carboxylase
RUMAL_RS15975	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
RUMAL_RS15980	COG0825	malonyl-CoA metabolic process
RUMAL_RS16015	COG0460	homoserine dehydrogenase
RUMAL_RS16020	COG4492	Belongs to the UPF0735 family
RUMAL_RS16035	COG1269	ATP hydrolysis coupled proton transport
RUMAL_RS16070	COG1394	ATPase activity, coupled to movement of substances
RUMAL_RS16085	COG0386	Belongs to the glutathione peroxidase family
RUMAL_RS16090	COG1846	Transcriptional regulator
RUMAL_RS16100	COG0492	ferredoxin-NADP+ reductase activity
RUMAL_RS16120	COG1012	belongs to the aldehyde dehydrogenase family
RUMAL_RS16120	COG1454	alcohol dehydrogenase
RUMAL_RS16130	COG0395	ABC-type sugar transport system, permease component
RUMAL_RS16135	COG1175	transmembrane transport
RUMAL_RS16155	COG0395	ABC-type sugar transport system, permease component
RUMAL_RS16175	COG0577	efflux transmembrane transporter activity
RUMAL_RS16175	COG1136	(ABC) transporter
RUMAL_RS16225	COG1307	EDD domain protein, DegV family
RUMAL_RS16230	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
RUMAL_RS16245	COG0519	Catalyzes the synthesis of GMP from XMP
RUMAL_RS16250	COG0516	GMP reductase activity
RUMAL_RS16250	COG0517	IMP dehydrogenase activity
RUMAL_RS16270	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
RUMAL_RS16275	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
RUMAL_RS16280	COG0612	Peptidase, M16
RUMAL_RS16285	COG0612	Peptidase, M16
RUMAL_RS16295	COG3706	GGDEF domain
RUMAL_RS16305	COG1192	Involved in chromosome partitioning
RUMAL_RS16310	COG1475	DNA binding
RUMAL_RS16575	COG1002	Type II restriction enzyme, methylase subunits
RUMAL_RS16590	COG0582	viral genome integration into host DNA
RUMAL_RS16640	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RUMAL_RS16645	COG1408	metallophosphoesterase
RUMAL_RS16660	COG0706	membrane insertase activity
RUMAL_RS16665	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
RUMAL_RS16670	COG0594	ribonuclease P activity
RUMAL_RS16675	COG0230	Belongs to the bacterial ribosomal protein bL34 family
RUMAL_RS17090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
RUMAL_RS17190	COG2385	sporulation resulting in formation of a cellular spore
RUMAL_RS17295	COG0577	efflux transmembrane transporter activity
RUMAL_RS17295	COG1136	(ABC) transporter
RUMAL_RS17365	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
RUMAL_RS17585	COG3459	Glycosyltransferase 36 associated
RUMAL_RS17720	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
RUMAL_RS17970	COG0151	Belongs to the GarS family
RUMAL_RS18155	COG1132	(ABC) transporter
RUMAL_RS18160	COG1132	(ABC) transporter
RUMAL_RS18245	COG0574	Belongs to the PEP-utilizing enzyme family
RUMAL_RS18245	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
RUMAL_RS18250	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
RUMAL_RS18250	COG0574	Belongs to the PEP-utilizing enzyme family
RUMAL_RS18665	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
RUMAL_RS18975	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
RUMAL_RS19640	COG0246	Mannitol dehydrogenase
RUMAL_RS19915	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
RUMAL_RS19965	COG0151	Belongs to the GarS family
RUMAL_RS20235	COG4124	Belongs to the glycosyl hydrolase 26 family
RUMAL_RS20290	COG0187	DNA topoisomerase II activity
RUMAL_RS20385	COG0187	DNA topoisomerase II activity
RUMAL_RS20390	COG0187	DNA topoisomerase II activity
RUMAL_RS20405	COG4977	sequence-specific DNA binding
RUMAL_RS20405	COG1917	Cupin 2, conserved barrel domain protein
RUMAL_RS20415	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RUMAL_RS20445	COG0784	Response regulator, receiver
RUMAL_RS20445	COG3437	response regulator, receiver
RUMAL_RS20475	COG5520	Belongs to the glycosyl hydrolase 30 family
RUMAL_RS20495	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RUMAL_RS20505	COG1621	beta-fructofuranosidase activity
RUMAL_RS20510	COG1621	beta-fructofuranosidase activity
RUMAL_RS20550	COG2070	2-Nitropropane dioxygenase
RUMAL_RS20555	COG2070	2-Nitropropane dioxygenase
RUMAL_RS20605	COG3693	PFAM glycoside hydrolase, family 10
RUMAL_RS20605	COG3507	Belongs to the glycosyl hydrolase 43 family
RUMAL_RS20605	COG2382	esterase
RUMAL_RS20630	COG5001	Diguanylate cyclase
RUMAL_RS20695	COG3507	Belongs to the glycosyl hydrolase 43 family
RUMAL_RS20705	COG3437	response regulator, receiver
RUMAL_RS20705	COG0784	Response regulator, receiver
RUMAL_RS20725	COG5433	transposase activity
RUMAL_RS20735	COG1686	Belongs to the peptidase S11 family
RUMAL_RS20740	COG5002	protein histidine kinase activity
RUMAL_RS20760	COG3507	Belongs to the glycosyl hydrolase 43 family
RUMAL_RS20795	COG2199	diguanylate cyclase activity
RUMAL_RS20795	COG2203	Gaf domain
RUMAL_RS20800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RUMAL_RS20820	COG0719	Fe-S assembly protein
RUMAL_RS20895	COG1994	Peptidase M50
RUMAL_RS20925	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex