locus-tag	class	description
RGna_RS00015	ENOG4106BHR	ftsk SpoIIIE family protein
RGna_RS00045	ENOG4105D3Q	Sugar transferase
RGna_RS00055	ENOG4108KGH	TRANSCRIPTIONal
RGna_RS00060	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
RGna_RS00085	ENOG4108KMV	Glycosyl transferase (Group 1
RGna_RS00090	ENOG4105K64	Glycosyl transferase, family 2
RGna_RS00120	ENOG4108KMV	Glycosyl transferase (Group 1
RGna_RS00135	ENOG4107YYJ	Glycosyl transferase, family 2
RGna_RS00150	ENOG4108IGT	Dipeptidase
RGna_RS00170	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
RGna_RS00175	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
RGna_RS00180	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
RGna_RS00190	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
RGna_RS00195	ENOG4105CAS	nag kinase
RGna_RS00200	ENOG4105C8Y	Acetylornithine aminotransferase
RGna_RS00210	ENOG4105KQC	Competence protein
RGna_RS00215	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
RGna_RS00220	ENOG4105BZU	Histidine kinase
RGna_RS00230	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
RGna_RS00355	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
RGna_RS00380	ENOG4105DVF	Cytosine-specific methyltransferase
RGna_RS00415	ENOG4105CAR	Terminase, large subunit
RGna_RS00425	ENOG4105EFC	phage portal protein HK97 family
RGna_RS00430	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
RGna_RS00475	ENOG4105DQ6	Transposase
RGna_RS00510	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
RGna_RS00595	ENOG4105XSJ	toxin secretion phage lysis holin
RGna_RS00680	ENOG4107QZW	Altronate oxidoreductase
RGna_RS00685	ENOG4105CTX	dehydratase
RGna_RS00690	ENOG4105D2H	Uronic isomerase
RGna_RS00710	ENOG4105ETE	Transcriptional regulator (LacI family
RGna_RS00730	ENOG4105CSA	Coproporphyrinogen iii oxidase
RGna_RS00740	ENOG4105EFI	regulatoR
RGna_RS00745	ENOG4105BZU	Histidine kinase
RGna_RS00755	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
RGna_RS00760	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
RGna_RS00765	ENOG4105CFG	Acts as a chaperone (By similarity)
RGna_RS00770	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
RGna_RS00785	ENOG4107QI1	Mate efflux family protein
RGna_RS00795	ENOG4105DHS	permease protein
RGna_RS00800	ENOG4105CM4	permease protein
RGna_RS00805	ENOG4108IPW	abc transporter atp-binding protein
RGna_RS00820	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
RGna_RS00840	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
RGna_RS00850	ENOG4108ZJ4	polysaccharide deacetylase
RGna_RS00855	ENOG4105CUZ	uba thif-type nad fad binding protein
RGna_RS00860	ENOG4105D1H	recombination factor protein RarA
RGna_RS00870	ENOG4105N5T	Radical SAM Protein
RGna_RS00875	ENOG4105C6K	Malic enzyme
RGna_RS00880	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
RGna_RS00885	ENOG4107V9H	nitrite transporter
RGna_RS00890	ENOG41082DI	50s ribosomal protein l31
RGna_RS00895	ENOG4105CBJ	Metal-dependent enzyme
RGna_RS00900	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
RGna_RS00905	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
RGna_RS00940	ENOG4105CHM	Aminotransferase
RGna_RS00965	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
RGna_RS00990	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
RGna_RS00995	ENOG4105C6T	cysteine synthase
RGna_RS01000	ENOG4105KRI	phosphocarrier protein (HPr
RGna_RS01005	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
RGna_RS01030	ENOG4105DVT	helicase
RGna_RS01045	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
RGna_RS01085	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
RGna_RS01095	ENOG4105D7W	serine acetyltransferase
RGna_RS01100	ENOG4105C8N	cysteinyl-tRNA synthetase
RGna_RS01105	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
RGna_RS01110	ENOG4105C2N	RNA methyltransferase TrmH family group 3
RGna_RS01115	ENOG4105QIV	RNA polymerase
RGna_RS01135	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
RGna_RS01150	ENOG4105CEM	UPF0597 protein
RGna_RS01155	ENOG4105JVQ	RNA Polymerase
RGna_RS01170	ENOG4105C8J	)-transporter
RGna_RS01180	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
RGna_RS01190	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
RGna_RS01195	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
RGna_RS01205	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
RGna_RS01220	ENOG4105C22	threonyL-tRNA synthetase
RGna_RS01230	ENOG4105C02	permease
RGna_RS01235	ENOG4105CVG	Homoserine O-transsuccinylase
RGna_RS01245	ENOG4105CHM	Aminotransferase
RGna_RS01255	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
RGna_RS01260	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
RGna_RS01265	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
RGna_RS01270	ENOG4108JQC	penicillin-binding protein 1A
RGna_RS01285	ENOG4105C8J	)-transporter
RGna_RS01300	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
RGna_RS01325	ENOG4105UQX	Mate efflux family protein
RGna_RS01330	ENOG4105CSR	polyphosphate kinase 2
RGna_RS01335	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
RGna_RS01340	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
RGna_RS01355	ENOG4105C22	threonyL-tRNA synthetase
RGna_RS01365	ENOG4107RUE	extracellular solute-binding protein family 1
RGna_RS01370	ENOG4105F38	ABC transporter, permease
RGna_RS01375	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
RGna_RS01390	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
RGna_RS01400	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
RGna_RS01405	ENOG4105C01	Dihydroxy-acid dehydratase
RGna_RS01410	ENOG4105C7K	acetolactate synthase
RGna_RS01415	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
RGna_RS01420	ENOG4108JQ1	Dehydrogenase
RGna_RS01425	ENOG4107SDT	Homocitrate synthase
RGna_RS01430	ENOG4105DRR	Transcriptional regulator, GntR family
RGna_RS01440	ENOG4108AEY	RNA polymerase sigma factor
RGna_RS01450	ENOG4105C5H	ABC transporter
RGna_RS01455	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
RGna_RS01460	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
RGna_RS01465	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
RGna_RS01470	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
RGna_RS01475	ENOG4105CDY	transcriptional regulatory protein
RGna_RS01485	ENOG4108IQK	o-acetylhomoserine
RGna_RS01490	ENOG4105CVQ	ATP-dependent Clp protease, proteolytic subunit
RGna_RS01495	ENOG4105CNU	cell division protein FtsK
RGna_RS01505	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
RGna_RS01520	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
RGna_RS01525	ENOG4105BZ8	glutamate synthase
RGna_RS01550	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
RGna_RS01560	ENOG4107UWY	Methyltransferase
RGna_RS01585	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
RGna_RS01630	ENOG4108IG5	Transcriptional regulator
RGna_RS01640	ENOG4105BZ1	(ABC) transporter
RGna_RS01650	ENOG4107QMU	Mate efflux family protein
RGna_RS01660	ENOG4108ZX5	transcriptional regulator
RGna_RS01665	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
RGna_RS01690	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
RGna_RS01705	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
RGna_RS01710	ENOG4105Q2H	domain protein
RGna_RS01715	ENOG4105VUC	UPF0237 protein
RGna_RS01720	ENOG4105CAG	UPF0210 protein
RGna_RS01725	ENOG4105EPR	degv family
RGna_RS01735	ENOG4105BZU	Histidine kinase
RGna_RS01740	ENOG4107WD8	ABC transporter, permease
RGna_RS01745	ENOG4107WD8	ABC transporter, permease
RGna_RS01815	ENOG4105KFN	sortase, SrtB family
RGna_RS01835	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
RGna_RS01885	ENOG4105K4H	Nlp p60 protein
RGna_RS01890	ENOG4105UNS	Pfam:DUF419
RGna_RS01905	ENOG4105GR3	Histidine kinase
RGna_RS01910	ENOG4105ETX	regulatoR
RGna_RS01945	ENOG4107QHE	Choloylglycine hydrolase
RGna_RS01965	ENOG4105CDE	UPF0348 protein
RGna_RS01970	ENOG4105CJW	magnesium transporter
RGna_RS01975	ENOG4108IJ2	phosphate acetyltransferase
RGna_RS01990	ENOG41067VY	50S ribosomal protein L32
RGna_RS01995	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
RGna_RS02000	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
RGna_RS02005	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
RGna_RS02010	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
RGna_RS02015	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
RGna_RS02020	ENOG4105C7B	Threonine dehydratase
RGna_RS02055	ENOG4105NA0	Transcriptional regulator
RGna_RS02065	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
RGna_RS02075	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
RGna_RS02080	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
RGna_RS02090	ENOG4105DXU	ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity)
RGna_RS02100	ENOG4105E8R	UPF0173 metal-dependent hydrolase
RGna_RS02110	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
RGna_RS02115	ENOG4107QM2	Aldo Keto reductase
RGna_RS02125	ENOG4105CXT	aspartate transcarbamylase
RGna_RS02165	ENOG4105F23	Fibronectin-binding protein
RGna_RS02170	ENOG4105DSJ	YicC domain protein
RGna_RS02180	ENOG4105YMY	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
RGna_RS02185	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
RGna_RS02190	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
RGna_RS02210	ENOG4108FPN	Integrase
RGna_RS02355	ENOG4105K70	DNA-binding protein
RGna_RS02400	ENOG4105C4R	Atp-dependent dna helicase
RGna_RS02415	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
RGna_RS02545	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
RGna_RS02555	ENOG4105D7V	transposase
RGna_RS02565	ENOG4108KQY	
RGna_RS02610	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
RGna_RS02655	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
RGna_RS02675	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
RGna_RS02695	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
RGna_RS02715	ENOG4107Z0P	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
RGna_RS02745	ENOG4105CNT	hydrolase family 2
RGna_RS02755	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
RGna_RS02760	ENOG4105EEM	helicase
RGna_RS02780	ENOG4108VAC	response regulator
RGna_RS02790	ENOG41090T1	Membrane
RGna_RS02825	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
RGna_RS02830	ENOG4105C7N	Xanthine uracil vitamin C permease
RGna_RS02845	ENOG4105EPD	Oligopeptide transporter, Opt family
RGna_RS02850	ENOG4105CIN	aminoacyl-histidine dipeptidase
RGna_RS02865	ENOG4105C9A	Phoh family
RGna_RS02885	ENOG410867X	UPF0291 protein
RGna_RS02900	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
RGna_RS02905	ENOG4105DQ5	transport system permease protein
RGna_RS02910	ENOG4105E0A	ABC, transporter
RGna_RS02915	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
RGna_RS02925	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
RGna_RS02935	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
RGna_RS02940	ENOG4105CXI	aluminum resistance protein
RGna_RS02945	ENOG4105CBX	hi0933 family
RGna_RS02950	ENOG4105DZ0	fad dependent oxidoreductase
RGna_RS02975	ENOG4105CJN	penicillin-binding protein
RGna_RS02985	ENOG4107QMS	site-determining protein
RGna_RS02990	ENOG41083CN	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
RGna_RS02995	ENOG4105CNI	cell division protein FtsW
RGna_RS03000	ENOG4108Z5K	methylglyoxal synthase
RGna_RS03005	ENOG4105DZ1	carboxypeptidase
RGna_RS03010	ENOG4105WG9	Conserved Protein
RGna_RS03020	ENOG4105DFA	alanine racemase domain protein
RGna_RS03025	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
RGna_RS03035	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
RGna_RS03040	ENOG4105C34	Pseudouridine synthase
RGna_RS03045	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
RGna_RS03050	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
RGna_RS03065	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
RGna_RS03075	ENOG4107SET	aldo keto reductase
RGna_RS03095	ENOG4105BZ1	(ABC) transporter
RGna_RS03105	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
RGna_RS03115	ENOG4108WF2	Metal Dependent Phosphohydrolase
RGna_RS03120	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
RGna_RS03125	ENOG410812S	Rna-binding protein
RGna_RS03130	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
RGna_RS03135	ENOG4105K46	50S ribosomal protein l27
RGna_RS03150	ENOG4108IJ8	ABC transporter
RGna_RS03155	ENOG4105CFH	Aspartokinase
RGna_RS03160	ENOG4108Z66	YbaK ebsC protein
RGna_RS03195	ENOG4107R73	Mate efflux family protein
RGna_RS03200	ENOG4105DZ6	Band 7 protein
RGna_RS03205	ENOG4107VHA	regulatoR
RGna_RS03210	ENOG4105C6Z	Gluconate
RGna_RS03215	ENOG4105BZW	Glycerate kinase
RGna_RS03255	ENOG4106BHR	ftsk SpoIIIE family protein
RGna_RS03265	ENOG4106128	DNA-binding helix-turn-helix protein
RGna_RS03315	ENOG4105K4H	Nlp p60 protein
RGna_RS03355	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
RGna_RS03395	ENOG4105C0A	alcohol dehydrogenase
RGna_RS03410	ENOG4105C5Y	PTS System
RGna_RS03435	ENOG4105CCI	Myosin-Cross-Reactive Antigen
RGna_RS03440	ENOG4108IG5	Transcriptional regulator
RGna_RS03460	ENOG4108JYZ	YitT family
RGna_RS03480	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
RGna_RS03485	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
RGna_RS03490	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
RGna_RS03495	ENOG4108IQ6	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
RGna_RS03500	ENOG4108UI2	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity)
RGna_RS03505	ENOG4105C34	Pseudouridine synthase
RGna_RS03535	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
RGna_RS03555	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
RGna_RS03560	ENOG4106H78	methyltransferase
RGna_RS03575	ENOG4105DP4	dak2 domain fusion protein ylov
RGna_RS03590	ENOG4105VB9	50S ribosomal protein l28
RGna_RS03610	ENOG4105CJN	penicillin-binding protein
RGna_RS03615	ENOG4107QHZ	cell cycle protein
RGna_RS03620	ENOG4105CFP	Peptidase U32
RGna_RS03630	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
RGna_RS03635	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
RGna_RS03650	ENOG4107RZC	phospholipase d
RGna_RS03695	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
RGna_RS03720	ENOG41090E6	transcriptional regulator MERR family
RGna_RS03725	ENOG4107SVV	electron transport complex, RnfABCDGE type, B subunit
RGna_RS03730	ENOG4105DGN	Electron transport complex
RGna_RS03735	ENOG4105DZB	Electron transport complex
RGna_RS03745	ENOG4105D6A	Electron transport complex
RGna_RS03750	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
RGna_RS03755	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
RGna_RS03760	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
RGna_RS03765	ENOG4105CAT	Cytidine monophosphate kinase
RGna_RS03770	ENOG4105CBX	hi0933 family
RGna_RS03775	ENOG4106G6Q	Transcriptional regulator
RGna_RS03780	ENOG4105DC7	peptidase M24
RGna_RS03785	ENOG4107QSA	Oxaloacetate decarboxylase
RGna_RS03790	ENOG4105D9Q	decarboxylase (Beta subunit)
RGna_RS03805	ENOG4108HNZ	carboxyl transferase
RGna_RS03810	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
RGna_RS03815	ENOG4105DZ1	carboxypeptidase
RGna_RS03820	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
RGna_RS03825	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
RGna_RS03830	ENOG4105DIN	metallophosphoesterase
RGna_RS03835	ENOG4105DZ1	carboxypeptidase
RGna_RS03850	ENOG4105C87	Aminotransferase class I and II
RGna_RS03860	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
RGna_RS03915	ENOG4105D7A	ATP-binding protein
RGna_RS03950	ENOG4105M6F	mutator MutT protein
RGna_RS03955	ENOG4108F3G	Type I restriction-modification system, R subunit
RGna_RS03960	ENOG4105CDA	abc transporter atp-binding protein
RGna_RS03965	ENOG4105E5Q	amino acid AbC transporter
RGna_RS03970	ENOG4108HW3	(ABC) transporter
RGna_RS03975	ENOG4105M3W	utilization protein
RGna_RS03980	ENOG4105M3W	utilization protein
RGna_RS03985	ENOG4105KTW	ethanolamine utilization protein
RGna_RS03990	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
RGna_RS04005	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
RGna_RS04010	ENOG4105EJQ	L-serine dehydratase
RGna_RS04030	ENOG4105D82	Glutamate dehydrogenase
RGna_RS04040	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
RGna_RS04050	ENOG4105C3R	Methionine synthase
RGna_RS04060	ENOG4105SYT	Methylenetetrahydrofolate reductase
RGna_RS04065	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
RGna_RS04070	ENOG4107QQR	Sporulation
RGna_RS04075	ENOG4105S1Z	Stage IV sporulation protein B
RGna_RS04080	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
RGna_RS04085	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
RGna_RS04090	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
RGna_RS04095	ENOG4105DX0	Hemolysin A
RGna_RS04100	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
RGna_RS04110	ENOG41083BM	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
RGna_RS04115	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
RGna_RS04125	ENOG4108ZSR	alkaline shock protein
RGna_RS04130	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
RGna_RS04155	ENOG4105KQ4	Stage iii sporulation protein ad
RGna_RS04170	ENOG4105CD2	stage iii sporulation protein aa
RGna_RS04180	ENOG4105C5I	Dehydrogenase
RGna_RS04200	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
RGna_RS04205	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
RGna_RS04220	ENOG4107WD8	ABC transporter, permease
RGna_RS04255	ENOG4105DJ4	phosphatidylserine decarboxylase
RGna_RS04260	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
RGna_RS04280	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
RGna_RS04285	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
RGna_RS04305	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
RGna_RS04320	ENOG4105EQD	regulatoR
RGna_RS04325	ENOG4105C2F	Histidine kinase
RGna_RS04330	ENOG4105DTN	riboflavin biosynthesis protein ribF
RGna_RS04335	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
RGna_RS04340	ENOG4105SFS	phosphoesterase RecJ domain protein
RGna_RS04345	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
RGna_RS04350	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
RGna_RS04350	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
RGna_RS04360	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
RGna_RS04365	ENOG4105CHV	Transcription elongation factor NusA
RGna_RS04370	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
RGna_RS04375	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
RGna_RS04380	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
RGna_RS04390	ENOG4105CEF	Initiates the rapid degradation of small, acid-soluble proteins during spore germination (By similarity)
RGna_RS04395	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
RGna_RS04405	ENOG4105CID	antiterminator
RGna_RS04415	ENOG4105C3S	Mate efflux family protein
RGna_RS04425	ENOG4108ZP8	Acetolactate synthase small subunit
RGna_RS04435	ENOG4105C5X	domain protein
RGna_RS04445	ENOG4105CMR	udp-glucose 4-epimerase
RGna_RS04460	ENOG4105C5H	ABC transporter
RGna_RS04465	ENOG4105C08	Histidine kinase
RGna_RS04470	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
RGna_RS04475	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
RGna_RS04480	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
RGna_RS04495	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
RGna_RS04515	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
RGna_RS04520	ENOG4105C08	Histidine kinase
RGna_RS04525	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
RGna_RS04555	ENOG4105ETE	Transcriptional regulator (LacI family
RGna_RS04560	ENOG4105C2J	ABC transporter
RGna_RS04575	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
RGna_RS04580	ENOG4105CDA	abc transporter atp-binding protein
RGna_RS04590	ENOG4105DZ1	carboxypeptidase
RGna_RS04600	ENOG4105ST3	Transcriptional regulator
RGna_RS04605	ENOG4105EPR	degv family
RGna_RS04620	ENOG4105C01	Dihydroxy-acid dehydratase
RGna_RS04630	ENOG4105C6Z	Gluconate
RGna_RS04660	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
RGna_RS04665	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
RGna_RS04675	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
RGna_RS04680	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
RGna_RS04685	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
RGna_RS04690	ENOG4105CP7	Triose-phosphate isomerase
RGna_RS04695	ENOG4105BZA	Phosphoglycerate kinase
RGna_RS04705	ENOG4107RVV	histidinol phosphate phosphatase, hisj family
RGna_RS04710	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
RGna_RS04715	ENOG4107RIU	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins (By similarity)
RGna_RS04745	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
RGna_RS04750	ENOG410902V	Modulates RecA activity (By similarity)
RGna_RS04755	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
RGna_RS04765	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
RGna_RS04785	ENOG4108Z5K	methylglyoxal synthase
RGna_RS04795	ENOG4105DA5	(ABC) transporter
RGna_RS04800	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
RGna_RS04805	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
RGna_RS04810	ENOG4105C9U	ATP-dependent DNA helicase RecQ
RGna_RS04815	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
RGna_RS04825	ENOG4105C5H	ABC transporter
RGna_RS04830	ENOG4107TB6	phosphoglycerate mutase
RGna_RS04835	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
RGna_RS04840	ENOG4108VW9	Membrane
RGna_RS04850	ENOG4108ESZ	Glycogen debranching enzyme
RGna_RS04855	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
RGna_RS04860	ENOG41085AS	UPF0473 protein
RGna_RS04865	ENOG4105ENA	helicase
RGna_RS04870	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
RGna_RS04880	ENOG4105DWK	Membrane
RGna_RS04900	ENOG4105C8V	SAICAR synthetase
RGna_RS04910	ENOG4105DE4	1-phosphofructokinase
RGna_RS04915	ENOG4105E98	transcriptional regulator DeoR family
RGna_RS04935	ENOG4107QZB	decarboxylase
RGna_RS04955	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
RGna_RS04975	ENOG4108JA2	transcriptioN-repair coupling factor
RGna_RS04980	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
RGna_RS04995	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
RGna_RS05000	ENOG4105E65	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
RGna_RS05010	ENOG4105DAV	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
RGna_RS05015	ENOG4105FFI	sigma-e processing peptidase spoiiga
RGna_RS05020	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
RGna_RS05030	ENOG4105CNI	cell division protein FtsW
RGna_RS05035	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
RGna_RS05040	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
RGna_RS05045	ENOG4105CJN	penicillin-binding protein
RGna_RS05050	ENOG4105CJN	penicillin-binding protein
RGna_RS05075	ENOG4105EPR	degv family
RGna_RS05080	ENOG4105CNI	cell division protein FtsW
RGna_RS05085	ENOG4105CAQ	asparagine synthetase
RGna_RS05110	ENOG4108RYM	conjugative transposon protein
RGna_RS05135	ENOG4106BHR	ftsk SpoIIIE family protein
RGna_RS05140	ENOG4106128	DNA-binding helix-turn-helix protein
RGna_RS05225	ENOG4105C5H	ABC transporter
RGna_RS05275	ENOG4105BZU	Histidine kinase
RGna_RS05305	ENOG4105ETX	regulatoR
RGna_RS05320	ENOG4108YRB	methyltransferase
RGna_RS05350	ENOG4105C8T	Leucyl-tRNA synthetase
RGna_RS05355	ENOG4105BZG	amino acid carrier protein
RGna_RS05365	ENOG4108Z29	Flavodoxin
RGna_RS05385	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
RGna_RS05390	ENOG4105C1A	potassium transporter peripheral membrane
RGna_RS05395	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
RGna_RS05405	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
RGna_RS05410	ENOG4105FDP	GntR family transcriptional regulator
RGna_RS05415	ENOG4105C2W	permease
RGna_RS05430	ENOG4105VPX	protein, conserved in bacteria
RGna_RS05470	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
RGna_RS05475	ENOG41081F0	Precorrin-8x methylmutase
RGna_RS05480	ENOG4108YZT	Adenosylcobinamide kinase
RGna_RS05490	ENOG4107QSI	ABC, transporter
RGna_RS05495	ENOG4108JQ6	ABC transporter
RGna_RS05500	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
RGna_RS05505	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
RGna_RS05515	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
RGna_RS05520	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
RGna_RS05525	ENOG4107QZB	decarboxylase
RGna_RS05535	ENOG4108TGR	phosphatase
RGna_RS05540	ENOG4107XPA	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
RGna_RS05545	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
RGna_RS05550	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
RGna_RS05555	ENOG4107XSI	cobalt-precorrin-6y C15-methyltransferase
RGna_RS05560	ENOG4105E4R	Precorrin-3B C17-methyltransferase
RGna_RS05565	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
RGna_RS05570	ENOG4105DVK	Precorrin-2 c20-methyltransferase
RGna_RS05575	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
RGna_RS05580	ENOG4107PPM	cobalt chelatase
RGna_RS05590	ENOG4108V4M	Cobalt abc transporter
RGna_RS05600	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
RGna_RS05605	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
RGna_RS05610	ENOG4108JTQ	reductase
RGna_RS05615	ENOG4108P62	biosynthesis protein (CbiG)
RGna_RS05620	ENOG4105BZU	Histidine kinase
RGna_RS05630	ENOG4105VRS	hydrolase family 18
RGna_RS05635	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
RGna_RS05640	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
RGna_RS05645	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
RGna_RS05650	ENOG4107U9T	Pfam:Ribonuclease_BN
RGna_RS05670	ENOG4105D98	threonine synthase
RGna_RS05685	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
RGna_RS05690	ENOG4107QK3	aspartate-semialdehyde dehydrogenase (EC 1.2.1.11
RGna_RS05695	ENOG4105CH7	arginosuccinase
RGna_RS05700	ENOG4105WPN	DNA integration recombination invertion protein
RGna_RS05710	ENOG4105EFP	binding-protein-dependent transport systems inner membrane Component
RGna_RS05715	ENOG4105C8J	)-transporter
RGna_RS05720	ENOG4105ST3	Transcriptional regulator
RGna_RS05725	ENOG4107R73	Mate efflux family protein
RGna_RS05735	ENOG4105DKQ	ROK family
RGna_RS05740	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
RGna_RS05745	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
RGna_RS05750	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
RGna_RS05755	ENOG4105DPH	UPF0371 protein
RGna_RS05760	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
RGna_RS05765	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
RGna_RS05785	ENOG4105C3S	Mate efflux family protein
RGna_RS05790	ENOG4105BZ1	(ABC) transporter
RGna_RS05795	ENOG4108RAC	Rubrerythrin
RGna_RS05805	ENOG4105CM2	brancheD-chain amino acid aminotransferase
RGna_RS05810	ENOG4108ZP8	Acetolactate synthase small subunit
RGna_RS05815	ENOG4105C7K	acetolactate synthase
RGna_RS05820	ENOG4105FAV	ABC, transporter
RGna_RS05825	ENOG4105FDK	ABC transporter
RGna_RS05830	ENOG4105DSE	periplasmic solute binding protein
RGna_RS05845	ENOG4105D6E	homoserine dehydrogenase
RGna_RS05860	ENOG4105C9M	aspartyl-trna synthetase
RGna_RS05865	ENOG4105CUT	histidyl-tRNA synthetase
RGna_RS05870	ENOG4105D4P	Coproporphyrinogen iii oxidase
RGna_RS05875	ENOG4105C5X	domain protein
RGna_RS05880	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
RGna_RS05885	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
RGna_RS05895	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
RGna_RS05900	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
RGna_RS05910	ENOG4108M14	stage v sporulation protein t
RGna_RS05920	ENOG4105EAM	Na Pi-cotransporter
RGna_RS05930	ENOG4108QBV	Monogalactosyldiacylglycerol synthase
RGna_RS05935	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
RGna_RS05950	ENOG41090E6	transcriptional regulator MERR family
RGna_RS05960	ENOG4107GRR	phosphate transport regulator
RGna_RS05965	ENOG4105CJ3	phosphate transporter
RGna_RS05970	ENOG4107ZYR	domain protein
RGna_RS05975	ENOG4105CZN	Potassium uptake protein
RGna_RS05980	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
RGna_RS05990	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
RGna_RS05995	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
RGna_RS06000	ENOG4105DFM	M18 family aminopeptidase
RGna_RS06010	ENOG4105CPN	adenine deaminase
RGna_RS06015	ENOG4105CPN	adenine deaminase
RGna_RS06020	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
RGna_RS06025	ENOG4108SAY	Involved in DNA repair and RecF pathway recombination (By similarity)
RGna_RS06070	ENOG4105EG2	ABC transporter, permease
RGna_RS06090	ENOG4108ZIA	glycerol-3-phosphate responsive antiterminator
RGna_RS06095	ENOG4107RV5	Glycosyl hydrolase family 3 N-terminal domain protein
RGna_RS06105	ENOG4108NEV	two component transcriptional regulator, LytTR family
RGna_RS06140	ENOG4108JQ7	(ABC) transporter
RGna_RS06145	ENOG4105C3U	ABC transporter
RGna_RS06180	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
RGna_RS06185	ENOG4105C3G	gtp-binding protein
RGna_RS06190	ENOG4105VTR	Integrase
RGna_RS06200	ENOG4105JBR	DNA replication protein
RGna_RS06215	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
RGna_RS06220	ENOG4105BZU	Histidine kinase
RGna_RS06225	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
RGna_RS06250	ENOG4105D9P	serine threonine protein kinase
RGna_RS06255	ENOG4108ZF3	Phosphatase
RGna_RS06260	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
RGna_RS06265	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
RGna_RS06285	ENOG4105C25	Primosomal protein n'
RGna_RS06295	ENOG4108NJY	Repeat protein
RGna_RS06305	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
RGna_RS06310	ENOG4105VFF	UPF0102 protein
RGna_RS06315	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
RGna_RS06325	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
RGna_RS06335	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
RGna_RS06340	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
RGna_RS06345	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
RGna_RS06355	ENOG4105K5M	30s ribosomal protein S16
RGna_RS06370	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
RGna_RS06615	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
RGna_RS06645	ENOG4105YCI	dehydratase medium subunit
RGna_RS06650	ENOG41084PW	diol glycerol dehydratase reactivating factor large subunit
RGna_RS06655	ENOG4108ZFT	Dehydratase small subunit
RGna_RS06660	ENOG4105YCI	dehydratase medium subunit
RGna_RS06670	ENOG4105CU9	asparagine synthetase A
RGna_RS06680	ENOG4107S6Z	Na H antiporter
RGna_RS06685	ENOG4105DWF	phosphomethylpyrimidine kinase
RGna_RS06695	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
RGna_RS06700	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
RGna_RS06705	ENOG4105CAQ	asparagine synthetase
RGna_RS06710	ENOG4108S0H	Dipicolinic acid synthetase, b subunit
RGna_RS06720	ENOG4105EE0	oxidoreductase
RGna_RS06730	ENOG4105CAH	Chromate
RGna_RS06735	ENOG4108HKT	sucrose-6-phosphate hydrolase
RGna_RS06745	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
RGna_RS06755	ENOG4105DIQ	Transcriptional regulator
RGna_RS06775	ENOG4105CT8	Phosphorylase
RGna_RS06780	ENOG4105EWM	Histidine kinase
RGna_RS06785	ENOG4105CJZ	response regulator
RGna_RS06790	ENOG4105K7K	Transcriptional regulator
RGna_RS06805	ENOG4106P19	photosystem i assembly btpa
RGna_RS06815	ENOG4108KPW	sugar kinase
RGna_RS06825	ENOG4107VG4	Xylose isomerase domain protein TIM barrel
RGna_RS06835	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
RGna_RS06840	ENOG4105DTD	Dehydrogenase
RGna_RS06855	ENOG4105D7K	pfkb domain protein
RGna_RS06860	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
RGna_RS06875	ENOG4107QHQ	amino acid
RGna_RS06885	ENOG4105FDP	GntR family transcriptional regulator
RGna_RS06890	ENOG4105FDP	GntR family transcriptional regulator
RGna_RS06895	ENOG4105UQX	Mate efflux family protein
RGna_RS06900	ENOG4107TTA	Xylose isomerase domain protein TIM barrel
RGna_RS06905	ENOG4107Y0V	Not clear, may be involved in an isomerization step
RGna_RS06915	ENOG4107S6Z	Na H antiporter
RGna_RS06920	ENOG4105C5H	ABC transporter
RGna_RS06925	ENOG41080E8	Transcriptional regulator, Spx MgsR family
RGna_RS06950	ENOG4105DA5	(ABC) transporter
RGna_RS07160	ENOG4108UUM	single-stranded DNA-binding protein
RGna_RS07200	ENOG4107QJE	Chromosome Partitioning Protein
RGna_RS07320	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
RGna_RS07325	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
RGna_RS07335	ENOG4108SGK	Tetr family transcriptional regulator
RGna_RS07340	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
RGna_RS07350	ENOG4105E09	nadh pyrophosphatase
RGna_RS07355	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
RGna_RS07370	ENOG4107RWR	Sodium hydrogen exchanger
RGna_RS07375	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
RGna_RS07380	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
RGna_RS07385	ENOG4105FE9	pseudouridine synthase
RGna_RS07395	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
RGna_RS07440	ENOG4105CN1	protease
RGna_RS07445	ENOG4105E4C	Lytic transglycosylase catalytic
RGna_RS07450	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
RGna_RS07455	ENOG4105CAK	Cell division ATP-binding protein ftsE
RGna_RS07460	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
RGna_RS07505	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
RGna_RS07510	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
RGna_RS07535	ENOG4105CMU	LysR family (Transcriptional regulator
RGna_RS07560	ENOG4105K63	Thioredoxin
RGna_RS07570	ENOG4107RVG	penicillin-binding protein
RGna_RS07595	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
RGna_RS07600	ENOG4105E98	transcriptional regulator DeoR family
RGna_RS07610	ENOG4105CZC	PTS system ascorbate-specific transporter subunit IIC
RGna_RS07625	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
RGna_RS07630	ENOG4105KG3	cytidine deaminase
RGna_RS07640	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
RGna_RS07645	ENOG4105DIH	basic membrane
RGna_RS07670	ENOG4108JQ9	ABC transporter
RGna_RS07675	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
RGna_RS07680	ENOG4107QNG	Phosphoribosylglycinamide synthetase
RGna_RS07685	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
RGna_RS07690	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
RGna_RS07695	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
RGna_RS07720	ENOG4105E2X	shikimate dehydrogenase
RGna_RS07740	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
RGna_RS07745	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
RGna_RS07750	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
RGna_RS07755	ENOG4105CD3	dihydroorotase
RGna_RS07770	ENOG4105CS2	ec 3.2.1.21
RGna_RS07775	ENOG4105C5Y	PTS System
RGna_RS07780	ENOG4106KNT	transcriptional regulator
RGna_RS07785	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
RGna_RS07800	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
RGna_RS07810	ENOG4105DGA	Diaminopimelate dehydrogenase
RGna_RS07815	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
RGna_RS07820	ENOG4108UU4	oxidoreductase (Short chain dehydrogenase reductase family)
RGna_RS07825	ENOG4105VTR	Integrase
RGna_RS07875	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
RGna_RS07940	ENOG4105CT4	transporter
RGna_RS07945	ENOG4105C5Y	PTS System
RGna_RS07950	ENOG4105CID	antiterminator
RGna_RS07965	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
RGna_RS07990	ENOG4105D5D	udp-galactopyranose mutase
RGna_RS08000	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
RGna_RS08005	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
RGna_RS08035	ENOG4105BZU	Histidine kinase
RGna_RS08045	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
RGna_RS08085	ENOG4105PW4	Sugar fermentation stimulation protein homolog
RGna_RS08095	ENOG4105CDA	abc transporter atp-binding protein
RGna_RS08100	ENOG4105E5Q	amino acid AbC transporter
RGna_RS08105	ENOG4108HW3	(ABC) transporter
RGna_RS08130	ENOG4108EKI	Dehydrogenase
RGna_RS08140	ENOG4108ZT0	50S ribosomal protein l17
RGna_RS08145	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
RGna_RS08155	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
RGna_RS08165	ENOG41067V7	50S ribosomal protein L36
RGna_RS08170	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
RGna_RS08180	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
RGna_RS08185	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
RGna_RS08195	ENOG4105VPB	50S ribosomal protein L30
RGna_RS08200	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
RGna_RS08210	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
RGna_RS08215	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
RGna_RS08220	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
RGna_RS08235	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
RGna_RS08240	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
RGna_RS08245	ENOG41082SA	50s ribosomal protein l29
RGna_RS08250	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
RGna_RS08260	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
RGna_RS08270	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
RGna_RS08275	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
RGna_RS08295	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
RGna_RS08300	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
RGna_RS08315	ENOG4105VUF	Transcriptional regulator
RGna_RS08330	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
RGna_RS08340	ENOG4105CK5	oxidoreductase
RGna_RS08355	ENOG4108JE9	extracellular solute-binding protein family 1
RGna_RS08360	ENOG4105FTV	AraC Family Transcriptional Regulator
RGna_RS08365	ENOG4105FK9	beta-D-galactosidase beta subunit
RGna_RS08410	ENOG4105F5H	Glycosyl Hydrolase Family 88
RGna_RS08415	ENOG4105CX8	fg-gap repeat protein
RGna_RS08420	ENOG4105E0S	extracellular solute-binding protein family 1
RGna_RS08425	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
RGna_RS08435	ENOG4105W4W	Transcriptional regulator
RGna_RS08460	ENOG4105FKQ	transcriptional regulator
RGna_RS08485	ENOG4105CG3	alpha amylase, catalytic region
RGna_RS08495	ENOG4107SBB	4-alpha-glucanotransferase (EC 2.4.1.25)
RGna_RS08500	ENOG4108IUN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
RGna_RS08510	ENOG4108IUM	Glycogen debranching enzyme
RGna_RS08515	ENOG4105EG2	ABC transporter, permease
RGna_RS08520	ENOG4105D56	permease protein
RGna_RS08530	ENOG4105ETE	Transcriptional regulator (LacI family
RGna_RS08550	ENOG4105EA8	2-Nitropropane dioxygenase
RGna_RS08560	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
RGna_RS08565	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
RGna_RS08570	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
RGna_RS08575	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
RGna_RS08580	ENOG4105CHR	reductase
RGna_RS08585	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
RGna_RS08590	ENOG4105EA8	2-Nitropropane dioxygenase
RGna_RS08595	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
RGna_RS08600	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
RGna_RS08625	ENOG4105IKJ	beta-galactosidase small subunit
RGna_RS08635	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
RGna_RS08670	ENOG4105EYH	Exonuclease
RGna_RS08675	ENOG4107RFY	SbcCD D subunit
RGna_RS08705	ENOG4105KRI	phosphocarrier protein (HPr
RGna_RS08710	ENOG4105CIE	May be required for sporulation (By similarity)
RGna_RS08720	ENOG4105D4A	Cell wall formation (By similarity)
RGna_RS08725	ENOG4105C37	(CBS) domain
RGna_RS08740	ENOG4107QQR	Sporulation
RGna_RS08750	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
RGna_RS08755	ENOG4108KP7	hydrolase
RGna_RS08760	ENOG4108YZG	isomerase
RGna_RS08765	ENOG4105I1K	ABC transporter
RGna_RS08770	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
RGna_RS08785	ENOG4105BZ1	(ABC) transporter
RGna_RS08795	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
RGna_RS08815	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
RGna_RS08820	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
RGna_RS08825	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
RGna_RS08830	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
RGna_RS08845	ENOG4105CDW	Resistance protein
RGna_RS08855	ENOG4105C34	Pseudouridine synthase
RGna_RS08860	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
RGna_RS08870	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
RGna_RS08875	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
RGna_RS08890	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
RGna_RS08895	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
RGna_RS08900	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
RGna_RS08905	ENOG4105C08	Histidine kinase
RGna_RS08910	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
RGna_RS08920	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
RGna_RS08925	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
RGna_RS08930	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
RGna_RS08940	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
RGna_RS08950	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
RGna_RS08960	ENOG4105WDJ	50S ribosomal protein L33
RGna_RS08975	ENOG4105BZ8	glutamate synthase
RGna_RS08980	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
RGna_RS08990	ENOG41067QW	Transcriptional regulator
RGna_RS09015	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
RGna_RS09040	ENOG4105F3R	pts system mannose fructose sorbose family iid
RGna_RS09045	ENOG4105ETZ	PTS System
RGna_RS09080	ENOG4107V2S	Transcriptional regulator
RGna_RS09085	ENOG4105DY8	decarboxylase
RGna_RS09090	ENOG4105CAQ	asparagine synthetase
RGna_RS09100	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
RGna_RS09140	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
RGna_RS09145	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
RGna_RS09150	ENOG4108SWU	Histidine kinase
RGna_RS09165	ENOG4105C26	Dehydrogenase
RGna_RS09175	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
RGna_RS09235	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
RGna_RS09275	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
RGna_RS09320	ENOG4105DQ6	Transposase
RGna_RS09370	ENOG4105C19	ABC transporter
RGna_RS09380	ENOG4105CN1	protease
RGna_RS09405	ENOG4105K4H	Nlp p60 protein
RGna_RS09515	ENOG4108RAV	Conserved protein
RGna_RS09525	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
RGna_RS09535	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
RGna_RS09600	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
RGna_RS09625	ENOG4107ZBH	radical SAM domain protein
RGna_RS09640	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
RGna_RS09645	ENOG4105BZ1	(ABC) transporter
RGna_RS09655	ENOG4107HBJ	phospholipase C
RGna_RS09735	ENOG4105KFN	sortase, SrtB family
RGna_RS09750	ENOG4105C7H	Helicase, RecD TraA family
RGna_RS09775	ENOG4107R08	Integrase
RGna_RS09780	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
RGna_RS09790	ENOG4105EMN	RNA polymerase sigma factor
RGna_RS09800	ENOG4108VAC	response regulator
RGna_RS09805	ENOG4105C2F	Histidine kinase
RGna_RS09810	ENOG4105MT0	Sporulation transcriptional regulator spoiiid
RGna_RS09835	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
RGna_RS09850	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
RGna_RS09855	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
RGna_RS09870	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
RGna_RS09880	ENOG4105C0B	DNA polymerase III (alpha subunit)
RGna_RS09890	ENOG4105QNR	S1 RNA binding domain protein
RGna_RS09910	ENOG4105DRR	Transcriptional regulator, GntR family
RGna_RS09915	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
RGna_RS09930	ENOG4105E9Q	Acyl-transferase
RGna_RS09935	ENOG4105DAP	Nicotinate phosphoribosyltransferase
RGna_RS09940	ENOG4105CPF	Cell wall formation (By similarity)
RGna_RS09945	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
RGna_RS09950	ENOG410667J	hydrolase
RGna_RS09955	ENOG4105DWU	Membrane
RGna_RS09965	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
RGna_RS10005	ENOG4105CIG	ABC transporter
RGna_RS10030	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
RGna_RS10035	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
RGna_RS10040	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
RGna_RS10050	ENOG4105DK0	Indole-3-glycerol phosphate synthase
RGna_RS10060	ENOG4105DDQ	anthranilate synthase
RGna_RS10065	ENOG4105CRQ	synthase (Component I)
RGna_RS10115	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
RGna_RS10120	ENOG4105EQI	Metal Dependent Phosphohydrolase
RGna_RS10125	ENOG4105C0H	protease
RGna_RS10130	ENOG4105C98	muts2 protein
RGna_RS10135	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
RGna_RS10140	ENOG4105BZU	Histidine kinase
RGna_RS10155	ENOG4107S21	permease
RGna_RS10175	ENOG41084EF	Ferredoxin
RGna_RS10185	ENOG4105CDU	Replicative dna helicase
RGna_RS10190	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
RGna_RS10195	ENOG4105BZR	domain protein
RGna_RS10205	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
RGna_RS10210	ENOG4108UUM	single-stranded DNA-binding protein
RGna_RS10215	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
RGna_RS10225	ENOG4105KFN	sortase, SrtB family
RGna_RS10240	ENOG4106H31	ATP-dependent protease ATP-binding subunit-like protein
RGna_RS10275	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
RGna_RS10280	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
RGna_RS10290	ENOG4105C2F	Histidine kinase
RGna_RS10295	ENOG4105EQD	regulatoR
RGna_RS10330	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
RGna_RS10390	ENOG4105CNA	YD repeat protein
RGna_RS10445	ENOG4108IUS	Transketolase
RGna_RS10450	ENOG4108HHA	Transketolase
RGna_RS10465	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
RGna_RS10470	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
RGna_RS10475	ENOG4105C6E	dna polymerase iii
RGna_RS10480	ENOG4105CTQ	phosphohexokinase
RGna_RS10485	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
RGna_RS10500	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
RGna_RS10505	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
RGna_RS10510	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
RGna_RS10515	ENOG4105G3A	stage ii sporulation protein e
RGna_RS10530	ENOG4105VYY	sporulation protein yabp
RGna_RS10535	ENOG41082I2	s4 domain protein
RGna_RS10540	ENOG4105K70	DNA-binding protein
RGna_RS10555	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
RGna_RS10565	ENOG4107RFY	SbcCD D subunit
RGna_RS10570	ENOG4105C5S	asparaginyl-tRNA synthetase
RGna_RS10580	ENOG4107QHI	-hydrogenase
RGna_RS10585	ENOG4107QIZ	NADH dehydrogenase
RGna_RS10595	ENOG4105C5Q	Transcriptional regulator
RGna_RS10605	ENOG4106N3A	copper homeostasis protein cutc
RGna_RS10615	ENOG4105C5Y	PTS System
RGna_RS10620	ENOG4105CID	antiterminator
RGna_RS10625	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
RGna_RS10630	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
RGna_RS10635	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
RGna_RS10640	ENOG4108JJB	ABC transporter
RGna_RS10645	ENOG4108JJB	ABC transporter
RGna_RS10655	ENOG4107ZE5	PPIases accelerate the folding of proteins
RGna_RS10690	ENOG4105ETE	Transcriptional regulator (LacI family
RGna_RS10735	ENOG4105C19	ABC transporter
RGna_RS10740	ENOG4105BZ1	(ABC) transporter
RGna_RS10745	ENOG4105BZ1	(ABC) transporter
RGna_RS10760	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
RGna_RS10765	ENOG4105C7J	ABC transporter, permease
RGna_RS10785	ENOG4108RVA	ribokinase
RGna_RS10790	ENOG4107QW4	alcohol dehydrogenase
RGna_RS10795	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
RGna_RS10805	ENOG4105D7K	pfkb domain protein
RGna_RS10810	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
RGna_RS10815	ENOG4108JJB	ABC transporter
RGna_RS10820	ENOG4108JJB	ABC transporter
RGna_RS10835	ENOG4105ETE	Transcriptional regulator (LacI family
RGna_RS10865	ENOG4105CDU	Replicative dna helicase
RGna_RS10885	ENOG4105I8F	Histidine kinase
RGna_RS10900	ENOG4105VTR	Integrase
RGna_RS10910	ENOG4106128	DNA-binding helix-turn-helix protein
RGna_RS10955	ENOG41080XS	Cobyrinic acid ac-diamide synthase
RGna_RS10990	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
RGna_RS10995	ENOG4105F8V	Hydrolase, tatD family
RGna_RS11015	ENOG4107QM5	aconitate hydratase
RGna_RS11035	ENOG4105CT4	transporter
RGna_RS11045	ENOG4107QYV	phosphohexose isomerase
RGna_RS11070	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
RGna_RS11080	ENOG4105K59	histidine triad (HIT) protein
RGna_RS11085	ENOG4105BZU	Histidine kinase
RGna_RS11090	ENOG4107ZXI	Rhomboid family
RGna_RS11150	ENOG4107YWA	deoxycytidylate deaminase
RGna_RS11160	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
RGna_RS11165	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
RGna_RS11170	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
RGna_RS11180	ENOG4108CIP	transcriptional regulator
RGna_RS11185	ENOG4105CT4	transporter
RGna_RS11205	ENOG4108S6Z	Negative regulator of genetic competence
RGna_RS11215	ENOG4105K4H	Nlp p60 protein
RGna_RS11220	ENOG4105I3K	Ferric uptake regulator, Fur family
RGna_RS11225	ENOG4105KY8	Rubrerythrin
RGna_RS11240	ENOG4105JFG	SpoIID LytB domain protein
RGna_RS11255	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
RGna_RS11290	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
RGna_RS11295	ENOG4107Y70	Heat shock protein
RGna_RS11315	ENOG4105E33	succinate dehydrogenase
RGna_RS11335	ENOG4105C59	p-type ATPase
RGna_RS11390	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
RGna_RS11395	ENOG4105CE1	Ferrous iron transport protein b
RGna_RS11400	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
RGna_RS11430	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
RGna_RS11445	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
RGna_RS11455	ENOG4105FA0	parb-like partition protein
RGna_RS11460	ENOG4107QJE	Chromosome Partitioning Protein
RGna_RS11470	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
RGna_RS11475	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
RGna_RS11480	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
RGna_RS11485	ENOG4108Z7S	Single-stranded nucleic acid binding R3H domain-containing protein
RGna_RS11490	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
RGna_RS11495	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
RGna_RS11500	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
RGna_RS11505	ENOG4105VG0	50S ribosomal protein l34
RGna_RS11510	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
RGna_RS11515	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
RGna_RS11530	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
RGna_RS11535	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
RGna_RS11545	ENOG4106DSS	Tartrate dehydratase subunit alpha
RGna_RS11560	ENOG4107RSM	transcriptional regulator
RGna_RS11565	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
RGna_RS11570	ENOG4108UMI	ABC transporter, permease
RGna_RS11575	ENOG4105D01	(LipO)protein
RGna_RS11645	ENOG4105CXN	decarboxylase
RGna_RS11650	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
RGna_RS11660	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
RGna_RS11680	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
RGna_RS11690	ENOG4105FA2	dna polymerase iii
RGna_RS11695	ENOG4105MA4	psp1 domain protein
RGna_RS11700	ENOG41060K3	Methyltransferase
RGna_RS11705	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
RGna_RS11710	ENOG4108IJ9	(ABC) transporter
RGna_RS11725	ENOG4108JIC	nucleoside recognition domain protein
RGna_RS11740	ENOG4105DY9	regulatoR
RGna_RS11750	ENOG4105CNT	hydrolase family 2
RGna_RS11755	ENOG4107RBJ	symporter
RGna_RS11780	ENOG4108RE9	Phosphodiesterase
RGna_RS11800	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
RGna_RS11805	ENOG4105CZV	ABC transporter
RGna_RS11815	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
RGna_RS11825	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
RGna_RS11830	ENOG4108Z3G	3H domain protein
RGna_RS11835	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
RGna_RS11845	ENOG4105CGA	flagellar basal-body rod protein FlgG
RGna_RS11865	ENOG4105D3Q	Sugar transferase
RGna_RS11870	ENOG4106CD9	glycosyl transferase group 1
RGna_RS11875	ENOG4106WTF	Glycosyl transferase, family 2
RGna_RS11885	ENOG4107BJW	polysaccharide deacetylase
RGna_RS11890	ENOG4108KMV	Glycosyl transferase (Group 1
RGna_RS11900	ENOG4107STW	synthase
RGna_RS11920	ENOG4107YSK	Glycerol-3-phosphate cytidylyltransferase
RGna_RS11940	ENOG4105D2T	synthase
RGna_RS11970	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
RGna_RS11990	ENOG4105KFN	sortase, SrtB family
RGna_RS12010	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
RGna_RS12035	ENOG4105CNT	hydrolase family 2
RGna_RS12060	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
RGna_RS12070	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
RGna_RS12080	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
RGna_RS12085	ENOG4107RT5	aminobenzoyl-glutamate utilization protein B
RGna_RS12095	ENOG4105D1Q	UPF0246 protein
RGna_RS12105	ENOG4108Z03	MAF-like protein
RGna_RS12120	ENOG4105CB5	ATP-dependent DNA helicase recG
RGna_RS12130	ENOG4107RFS	it plays a direct role in the translocation of protons across the membrane (By similarity)
RGna_RS12135	ENOG41082I9	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
RGna_RS12140	ENOG4107ZFM	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
RGna_RS12145	ENOG4105E3N	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
RGna_RS12150	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
RGna_RS12155	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
RGna_RS12160	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
RGna_RS12165	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
RGna_RS12180	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
RGna_RS12195	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
RGna_RS12205	ENOG4105CJG	carbon-monoxide dehydrogenase catalytic subunit
RGna_RS12215	ENOG4105ETE	Transcriptional regulator (LacI family
RGna_RS12220	ENOG4108RVA	ribokinase
RGna_RS12230	ENOG4105C2J	ABC transporter
RGna_RS12235	ENOG4105CNN	ABC, transporter
RGna_RS12240	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
RGna_RS12260	ENOG4105BZ1	(ABC) transporter
RGna_RS12285	ENOG4105C9U	ATP-dependent DNA helicase RecQ
RGna_RS12295	ENOG4105WD1	Membrane
RGna_RS12300	ENOG4105VXR	cytoplasmic protein
RGna_RS12305	ENOG4108JJ9	ABC, transporter
RGna_RS12310	ENOG4105BZ1	(ABC) transporter
RGna_RS12340	ENOG4105CXN	decarboxylase
RGna_RS12345	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
RGna_RS12350	ENOG4105CYW	agmatinase
RGna_RS12365	ENOG4105BZ8	glutamate synthase
RGna_RS12375	ENOG4105C26	Dehydrogenase
RGna_RS12400	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
RGna_RS12435	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
RGna_RS12440	ENOG4107URF	beta-phospho-glucomutase
RGna_RS12445	ENOG4107T5V	SNARE associated Golgi
RGna_RS12450	ENOG4105BZF	Glycosyl transferase (Group 1
RGna_RS12465	ENOG4105BZU	Histidine kinase
RGna_RS12485	ENOG4106AXJ	AraC family transcriptional regulator
RGna_RS12495	ENOG4105BZ1	(ABC) transporter
RGna_RS12510	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
RGna_RS12520	ENOG4107QW8	radical SAM domain protein
RGna_RS12525	ENOG41084AG	Acylphosphatase
RGna_RS12530	ENOG4105II7	pyrroline-5-carboxylate reductase
RGna_RS12535	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
RGna_RS12555	ENOG4107XVH	Transcriptional regulator
RGna_RS12560	ENOG4105C2F	Histidine kinase
RGna_RS12570	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
RGna_RS12575	ENOG4105C3M	thioredoxin reductase
RGna_RS12585	ENOG4105W8Z	4'-phosphopantetheinyl transferase
RGna_RS12590	ENOG4108VXD	carboxy-peptidase
RGna_RS12600	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
RGna_RS12610	ENOG4108Z6B	deaminase
RGna_RS12635	ENOG4108ZB6	transcriptional regulator AsnC family
RGna_RS12640	ENOG4105CHM	Aminotransferase
RGna_RS12685	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
RGna_RS12690	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
RGna_RS12695	ENOG4105M56	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
RGna_RS12730	ENOG4105E0A	ABC, transporter
RGna_RS12740	ENOG4105DDC	Oxidoreductase domain protein
RGna_RS12745	ENOG4108K01	transcriptional regulator
RGna_RS12760	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
RGna_RS12765	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
RGna_RS12775	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
RGna_RS12780	ENOG4105BZU	Histidine kinase
RGna_RS12785	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
RGna_RS12790	ENOG4105CZN	Potassium uptake protein
RGna_RS12795	ENOG4107ZYR	domain protein
RGna_RS12800	ENOG4108RWN	rrna methyltransferase
RGna_RS12805	ENOG4105DBV	ornithine carbamoyltransferase
RGna_RS12810	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
RGna_RS12820	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
RGna_RS12825	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
RGna_RS12830	ENOG4105CRK	lysyL-tRNA synthetase
RGna_RS12845	ENOG4107QJE	Chromosome Partitioning Protein
RGna_RS12860	ENOG4105ETZ	PTS System
RGna_RS12865	ENOG4105F3R	pts system mannose fructose sorbose family iid
RGna_RS12870	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
RGna_RS12875	ENOG4105DCT	glycerol dehydrogenase
RGna_RS12890	ENOG4108WS4	fmn reductase
RGna_RS12920	ENOG4108K8K	Transcriptional regulator
RGna_RS12925	ENOG4107QYR	Signal peptidase i
RGna_RS12935	ENOG4105KFN	sortase, SrtB family
RGna_RS12950	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
RGna_RS12960	ENOG4108IFG	nitrite reductase, (NAD(P)H)
RGna_RS13035	ENOG4108IUK	alpha amylase, catalytic
RGna_RS13075	ENOG4105CTQ	phosphohexokinase
RGna_RS13080	ENOG4108SHN	Glycosyl transferase, family 2
RGna_RS13085	ENOG4108RAC	Rubrerythrin
RGna_RS13125	ENOG4106C6A	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
RGna_RS13130	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
RGna_RS13135	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
RGna_RS13175	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
RGna_RS13180	ENOG4105K63	Thioredoxin
RGna_RS13190	ENOG4105EQD	regulatoR
RGna_RS13205	ENOG4105ETE	Transcriptional regulator (LacI family
RGna_RS13215	ENOG4108HHA	Transketolase
RGna_RS13220	ENOG4108IUS	Transketolase
RGna_RS13225	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
RGna_RS13395	ENOG4108UUM	single-stranded DNA-binding protein
RGna_RS13475	ENOG4105DEU	major facilitator superfamily
RGna_RS13480	ENOG4105DFM	M18 family aminopeptidase
RGna_RS13485	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
RGna_RS13500	ENOG4108Z4K	mutator MutT protein
RGna_RS13505	ENOG4108UT2	hemolysin iii
RGna_RS13510	ENOG4105C1J	atp-dependent rna helicase
RGna_RS13560	ENOG4105C5B	carbamate kinase
RGna_RS13575	ENOG4105BZ1	(ABC) transporter
RGna_RS13585	ENOG4108IUW	ABC transporter
RGna_RS13590	ENOG4108SDH	ABC, transporter
RGna_RS13610	ENOG4105CGK	Exodeoxyribonuclease III
RGna_RS13615	ENOG4105CKI	cobalamin synthesis protein
RGna_RS13625	ENOG4105D7K	pfkb domain protein
RGna_RS13635	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
RGna_RS13645	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
RGna_RS13660	ENOG4107QJE	Chromosome Partitioning Protein
RGna_RS13665	ENOG4105FA0	parb-like partition protein
RGna_RS13685	ENOG4105WXW	Antirepressor
RGna_RS13740	ENOG4105EKQ	RNA-directed DNA polymerase
RGna_RS13775	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
RGna_RS13855	ENOG4105C9U	ATP-dependent DNA helicase RecQ
RGna_RS13865	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
RGna_RS13885	ENOG4105EKQ	RNA-directed DNA polymerase
RGna_RS13950	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
RGna_RS13955	ENOG4105BZU	Histidine kinase
RGna_RS13975	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
RGna_RS14005	ENOG4105CJZ	response regulator
RGna_RS14015	ENOG4105C19	ABC transporter
RGna_RS14060	ENOG4105DFS	Conserved Protein
RGna_RS14080	ENOG4108WAV	Transcriptional regulator
RGna_RS14095	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
RGna_RS14120	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
RGna_RS14130	ENOG4105HDK	L-asparaginase
RGna_RS14150	ENOG4105C37	(CBS) domain
RGna_RS14160	ENOG4105DC1	bifunctional purine biosynthesis protein purh
RGna_RS14165	ENOG4105K8N	protein family UPF0079, ATPase
RGna_RS14170	ENOG41072GX	Peptidase M22 Glycoprotease
RGna_RS14180	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
RGna_RS14190	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
RGna_RS14295	ENOG4105EMS	pseudouridine synthase
RGna_RS14305	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
RGna_RS14310	ENOG4105FH5	Membrane
RGna_RS14315	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
RGna_RS14320	ENOG4108SAX	Membrane
RGna_RS14325	ENOG4107QJQ	Mate efflux family protein
RGna_RS14345	ENOG4105F0V	Cell wall hydrolase
RGna_RS14350	ENOG4105C9U	ATP-dependent DNA helicase RecQ
RGna_RS14360	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
RGna_RS14370	ENOG4105DA5	(ABC) transporter
RGna_RS14380	ENOG4105CID	antiterminator
RGna_RS14385	ENOG4105C5Y	PTS System
RGna_RS14390	ENOG4105CS2	ec 3.2.1.21
RGna_RS14400	ENOG4105XZU	Preprotein translocase, subunit SecG
RGna_RS14405	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
RGna_RS14410	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
RGna_RS14425	ENOG4107XVH	Transcriptional regulator
RGna_RS14440	ENOG4105CMG	Carbohydrate kinase
RGna_RS14445	ENOG4105C4C	beta-galactosidase
RGna_RS14460	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
RGna_RS14470	ENOG410667J	hydrolase
RGna_RS14510	ENOG4105VTR	Integrase
RGna_RS14525	ENOG4108HQR	Glycine betaine
RGna_RS14560	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
RGna_RS14565	ENOG4105BZU	Histidine kinase
RGna_RS14570	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
RGna_RS14575	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
RGna_RS14590	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
RGna_RS14600	ENOG4107R34	abc transporter permease protein
RGna_RS14615	ENOG4105WH1	Two component transcriptional regulator luxr family
RGna_RS14620	ENOG4105BZU	Histidine kinase
RGna_RS14625	ENOG4105CJ1	ABC, transporter
RGna_RS14640	ENOG4105CAQ	asparagine synthetase
RGna_RS14650	ENOG4105BZ8	glutamate synthase
RGna_RS14665	ENOG4107QSS	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli (By similarity)
RGna_RS14680	ENOG4108MCI	Transcriptional regulator, ARAC family
RGna_RS14690	ENOG4105EP8	Glycosyl Hydrolase Family 88
RGna_RS14695	ENOG4108RG5	PTS system N-acetylgalactosamine-specific transporter subunit IIB
RGna_RS14700	ENOG4105ETZ	PTS System
RGna_RS14705	ENOG4105F3R	pts system mannose fructose sorbose family iid
RGna_RS14715	ENOG4108M60	Transcriptional regulator
RGna_RS14730	ENOG4106R3P	AraC family transcriptional regulator
RGna_RS14735	ENOG4105CNT	hydrolase family 2
RGna_RS14740	ENOG4105CT4	transporter
RGna_RS14750	ENOG4105BZU	Histidine kinase
RGna_RS14755	ENOG4105C59	p-type ATPase
RGna_RS14765	ENOG4105C59	p-type ATPase
RGna_RS14780	ENOG4107QIV	Cytochrome c biogenesis protein
RGna_RS14785	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
RGna_RS14790	ENOG4105KVH	Transcriptional regulator
RGna_RS14805	ENOG4105EHR	propanediol utilization protein pduB
RGna_RS14810	ENOG4105CHR	reductase
RGna_RS14815	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
RGna_RS14825	ENOG4107XVH	Transcriptional regulator
RGna_RS14835	ENOG41067QW	Transcriptional regulator
RGna_RS14845	ENOG4107XVH	Transcriptional regulator
RGna_RS14850	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
RGna_RS14855	ENOG4105CHR	reductase
RGna_RS14865	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
RGna_RS14870	ENOG41069H7	transport system small permease component
RGna_RS14875	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
RGna_RS14880	ENOG4105T16	Transcriptional regulator (AraC family)
RGna_RS14885	ENOG4105F5H	Glycosyl Hydrolase Family 88
RGna_RS14890	ENOG4105DET	Rhamnulokinase
RGna_RS14895	ENOG4105DKG	l-rhamnose isomerase
RGna_RS14900	ENOG4108MCI	Transcriptional regulator, ARAC family
RGna_RS14910	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
RGna_RS14915	ENOG41069H7	transport system small permease component
RGna_RS14920	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
RGna_RS14935	ENOG4105DCG	PHP domain protein
RGna_RS14940	ENOG4105C6N	Formate acetyltransferase
RGna_RS14945	ENOG4105F1A	Pyruvate formate-lyase
RGna_RS14960	ENOG4108EKI	Dehydrogenase
RGna_RS14965	ENOG4105CPQ	Dehydrogenase
RGna_RS14975	ENOG4105KNY	Microcompartments protein
RGna_RS14985	ENOG4105KNY	Microcompartments protein
RGna_RS14990	ENOG4108VPX	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity)
RGna_RS14995	ENOG4105WVM	ethanolamine utilization protein EutN carboxysome structural protein Ccml
RGna_RS15000	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
RGna_RS15010	ENOG4105E98	transcriptional regulator DeoR family
RGna_RS15025	ENOG4105T16	Transcriptional regulator (AraC family)
RGna_RS15030	ENOG4105C2J	ABC transporter
RGna_RS15035	ENOG4105CNN	ABC, transporter
RGna_RS15040	ENOG4105F5R	ABC transporter
RGna_RS15050	ENOG4105CMG	Carbohydrate kinase
RGna_RS15055	ENOG4105M10	Involved in the anomeric conversion of L-rhamnose (By similarity)
RGna_RS15060	ENOG4105T16	Transcriptional regulator (AraC family)
RGna_RS15065	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
RGna_RS15075	ENOG4105D2H	Uronic isomerase
RGna_RS15080	ENOG4105J4Q	Transcriptional regulator
RGna_RS15085	ENOG4108UHU	Aldolase
RGna_RS15095	ENOG4105D2N	Aldolase
RGna_RS15100	ENOG4105ETE	Transcriptional regulator (LacI family
RGna_RS15105	ENOG4105CMG	Carbohydrate kinase
RGna_RS15110	ENOG4107WTH	Galactitol-1-phosphate dehydrogenase
RGna_RS15115	ENOG4105DE4	1-phosphofructokinase
RGna_RS15120	ENOG4105CV8	reductase
RGna_RS15135	ENOG4105C5Y	PTS System
RGna_RS15145	ENOG4105C2F	Histidine kinase
RGna_RS15155	ENOG4108HWW	ABC transporter
RGna_RS15160	ENOG4105C2J	ABC transporter
RGna_RS15165	ENOG4108HWV	)-transporter
RGna_RS15185	ENOG4105DET	Rhamnulokinase
RGna_RS15190	ENOG4105EHF	Converts the aldose L-fucose into the corresponding ketose L-fuculose (By similarity)
RGna_RS15195	ENOG4105NWF	RbsD or FucU transport
RGna_RS15205	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
RGna_RS15215	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
RGna_RS15225	ENOG41082AN	stage II sporulation protein
RGna_RS15235	ENOG4105CT2	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
RGna_RS15265	ENOG41090VF	Stage v sporulation protein ac
RGna_RS15280	ENOG4105EAM	Na Pi-cotransporter
RGna_RS15285	ENOG4107S17	Phosphate-binding protein
RGna_RS15290	ENOG4105C8U	phosphate abc transporter
RGna_RS15295	ENOG4105E2Z	phosphate ABC transporter (Permease
RGna_RS15305	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
RGna_RS15310	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
RGna_RS15315	ENOG4105BZU	Histidine kinase
RGna_RS15320	ENOG4108W3Q	Transcriptional regulator
RGna_RS15325	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
RGna_RS15330	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
RGna_RS15335	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
RGna_RS15345	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
RGna_RS15400	ENOG4105C7W	Xanthine dehydrogenase
RGna_RS15440	ENOG4105F1A	Pyruvate formate-lyase
RGna_RS15455	ENOG4108ZT1	Transcriptional regulator
RGna_RS15465	ENOG4105BZ1	(ABC) transporter
RGna_RS15475	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
RGna_RS15495	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
RGna_RS15500	ENOG4107QI6	Cysteine desulfurase
RGna_RS15505	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
RGna_RS15515	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
RGna_RS15520	ENOG4105VBH	UPF0297 protein
RGna_RS15535	ENOG4105I3K	Ferric uptake regulator, Fur family
RGna_RS15540	ENOG4105CN5	Metallo-Beta-Lactamase
RGna_RS15545	ENOG4108VQJ	O-methyltransferase
RGna_RS15550	ENOG4105CFP	Peptidase U32
RGna_RS15555	ENOG4105DMD	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
RGna_RS15560	ENOG4105C0P	Mg chelatase subunit ChlI
RGna_RS15565	ENOG4105C79	DNA protecting protein DprA
RGna_RS15570	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
RGna_RS15655	ENOG4107R21	site-determining protein
RGna_RS15680	ENOG4105Z8H	single-stranded DNA-binding protein
RGna_RS15705	ENOG4105CAR	Terminase, large subunit
RGna_RS15815	ENOG4105QHJ	toxin secretion phage lysis holin
RGna_RS15840	ENOG4105EUM	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor (By similarity)
RGna_RS15850	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
RGna_RS15855	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
RGna_RS15860	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
RGna_RS15870	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
RGna_RS15875	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
RGna_RS15900	ENOG4105CZV	ABC transporter
RGna_RS15905	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
RGna_RS15910	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
RGna_RS15920	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
RGna_RS15925	ENOG4108TYN	CAAX amino terminal protease family protein
RGna_RS15955	ENOG4105K4H	Nlp p60 protein
RGna_RS15960	ENOG4107XDR	Lactoylglutathione lyase
RGna_RS15965	ENOG4105CE9	30S ribosomal protein S2
RGna_RS15970	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
RGna_RS15985	ENOG4105CHR	reductase
RGna_RS15995	ENOG4108TFM	Kinase, PfkB family
RGna_RS16000	ENOG4108KD5	ADP-ribosylation crystallin J1
RGna_RS16005	ENOG4105CZE	histidine utilization repressor
RGna_RS16010	ENOG4108IAB	Phoh family
RGna_RS16015	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
RGna_RS16025	ENOG4105DBI	uridine monophosphokinase
RGna_RS16030	ENOG4105D7N	magnesium and cobalt transport protein CorA
RGna_RS16045	ENOG4105ETE	Transcriptional regulator (LacI family
RGna_RS16065	ENOG4105C5B	carbamate kinase
RGna_RS16070	ENOG4105KME	endoribonuclease L-psp
RGna_RS16075	ENOG4105IW6	Carbamoyltransferase
RGna_RS16080	ENOG4107S4Y	M20 DapE family protein YgeY
RGna_RS16085	ENOG4107RCH	Diaminopropionate ammonia-lyase
RGna_RS16095	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
RGna_RS16100	ENOG4105BZ8	glutamate synthase
RGna_RS16105	ENOG4105MJ6	selenium-dependent hydroxylase accessory protein YqeC
RGna_RS16110	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
RGna_RS16120	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
RGna_RS16125	ENOG4105E0C	molybdate abc transporter
RGna_RS16150	ENOG4105D2X	ABC transporter substrate-binding protein
RGna_RS16170	ENOG41067QW	Transcriptional regulator
RGna_RS16240	ENOG4105QBX	endodeoxyribonuclease RusA
RGna_RS16430	ENOG4105D2X	ABC transporter substrate-binding protein
RGna_RS16445	ENOG4105KGF	protein, YerC YecD
RGna_RS16460	ENOG4105C4R	Atp-dependent dna helicase
RGna_RS16470	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
RGna_RS16490	ENOG4105BZ1	(ABC) transporter
RGna_RS16515	ENOG4108RDQ	ABC transporter
RGna_RS16615	ENOG4105DA5	(ABC) transporter
RGna_RS16635	ENOG4108C33	Resolvase
RGna_RS16660	ENOG4105FB9	CRISPR-associated protein
RGna_RS16680	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
RGna_RS16685	ENOG4105KCF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
RGna_RS16695	ENOG4105BZU	Histidine kinase
RGna_RS16705	ENOG4105BZU	Histidine kinase
RGna_RS16710	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
RGna_RS16740	ENOG4107ZT5	Thiol disulfide interchange protein
RGna_RS16765	ENOG4105CE4	GlcNAc 6-P deacetylase
RGna_RS16770	ENOG4105CJW	magnesium transporter
RGna_RS16775	ENOG4108D32	Methyltransferase
RGna_RS16780	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
RGna_RS16785	ENOG4108DWA	Nad synthetase
RGna_RS16795	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
RGna_RS16800	ENOG4107QUY	Guanine deaminase
RGna_RS16805	ENOG4105C7W	Xanthine dehydrogenase
RGna_RS16810	ENOG4108HR6	Dehydrogenase
RGna_RS16815	ENOG4108UTP	(2Fe-2S)-binding domain protein
RGna_RS16830	ENOG4105I3K	Ferric uptake regulator, Fur family
RGna_RS16875	ENOG4105VEM	Conserved domain protein
RGna_RS16880	ENOG4105FA0	parb-like partition protein
RGna_RS16970	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
RGna_RS16980	ENOG4108WZ2	response regulator
RGna_RS17010	ENOG4105E2X	shikimate dehydrogenase
RGna_RS17015	ENOG4105D49	3-dehydroquinate synthase
RGna_RS17020	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
RGna_RS17025	ENOG4105CMQ	Chloride channel
RGna_RS17030	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
RGna_RS17035	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
RGna_RS17045	ENOG4105KNE	Phosphatidate cytidylyltransferase
RGna_RS17055	ENOG4105DZP	Membrane-associated zinc metalloprotease
RGna_RS17060	ENOG4105T4X	n-acetylmuramoyl-l-alanine amidase
RGna_RS17070	ENOG41067MG	lrgb family
RGna_RS17080	ENOG4107U9B	transcriptional regulator
RGna_RS17095	ENOG4105ECQ	AraC Family Transcriptional Regulator
RGna_RS17100	ENOG4107YY3	extracellular solute-binding protein family 1
RGna_RS17130	ENOG4108R6W	Transcriptional regulator, ARAC family
RGna_RS17135	ENOG4105EY8	ABC transporter
RGna_RS17150	ENOG4105XT2	Transcriptional regulator
RGna_RS17155	ENOG4108JYZ	YitT family
RGna_RS17165	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
RGna_RS17175	ENOG4105C3J	Cysteine desulfurase
RGna_RS17190	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
RGna_RS17195	ENOG4105MS2	ribosomal subunit Interface protein
RGna_RS17205	ENOG4105CI3	gtp-binding protein typa
RGna_RS17215	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
RGna_RS17220	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
RGna_RS17225	ENOG4105DMC	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3
RGna_RS17230	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
RGna_RS17240	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
RGna_RS17245	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
RGna_RS17255	ENOG4105D6E	homoserine dehydrogenase
RGna_RS17260	ENOG4105E3H	phosphoglycerate mutase
RGna_RS17285	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
RGna_RS17295	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
RGna_RS17300	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
RGna_RS17305	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
RGna_RS17310	ENOG4108REF	Sporulation integral membrane protein ytvi
RGna_RS17315	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
RGna_RS17325	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
RGna_RS17330	ENOG4105BZU	Histidine kinase
RGna_RS17335	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
RGna_RS17360	ENOG4105FDP	GntR family transcriptional regulator
RGna_RS17365	ENOG4105CJ1	ABC, transporter
RGna_RS17380	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
RGna_RS17385	ENOG4108SWU	Histidine kinase
RGna_RS17390	ENOG4107QW4	alcohol dehydrogenase
RGna_RS17395	ENOG4105CNW	domain protein
RGna_RS17400	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
RGna_RS17410	ENOG4105DFS	Conserved Protein
RGna_RS17430	ENOG4105C7H	Helicase, RecD TraA family
RGna_RS17435	ENOG4105MJ2	Competence protein
RGna_RS17475	ENOG4105CKK	Glycosyl transferase, family 2
RGna_RS17485	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
RGna_RS17495	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
RGna_RS17530	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
RGna_RS17540	ENOG4105CG5	Glycosyl transferase (Group 1
RGna_RS17545	ENOG4105K64	Glycosyl transferase, family 2
RGna_RS17555	ENOG4108KGH	TRANSCRIPTIONal
RGna_RS17565	ENOG4108KBE	Glycosyl transferase, family 2
RGna_RS17570	ENOG4108KGH	TRANSCRIPTIONal
RGna_RS17580	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
RGna_RS17585	ENOG4105C0H	protease
RGna_RS17615	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
RGna_RS17655	ENOG4105K4H	Nlp p60 protein