locus-tag	class	description
SULB_RS00005	COG0538	isocitrate dehydrogenase activity
SULB_RS00030	COG2154	pterin-4-alpha-carbinolamine dehydratase
SULB_RS00110	COG1331	Highly conserved protein containing a thioredoxin domain
SULB_RS00115	COG1028	Short-chain dehydrogenase reductase Sdr
SULB_RS00120	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
SULB_RS00130	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
SULB_RS00155	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SULB_RS00170	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SULB_RS00195	COG0492	ferredoxin-NADP+ reductase activity
SULB_RS00240	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
SULB_RS00265	COG0588	phosphoglycerate mutase activity
SULB_RS00295	COG1957	nucleoside hydrolase
SULB_RS00300	COG0735	belongs to the Fur family
SULB_RS00325	COG0497	DNA recombination
SULB_RS00345	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
SULB_RS00345	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SULB_RS00350	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SULB_RS00355	COG1892	Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle
SULB_RS00390	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SULB_RS00435	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SULB_RS00440	COG1573	uracil-dna glycosylase
SULB_RS00445	COG1028	Short-chain dehydrogenase reductase Sdr
SULB_RS00470	COG0215	cysteine-tRNA ligase activity
SULB_RS00475	COG2222	sugar isomerase
SULB_RS00485	COG0446	pyridine nucleotide-disulphide oxidoreductase
SULB_RS00495	COG0433	COG0433 Predicted ATPase
SULB_RS00505	COG1607	acyl-coa hydrolase
SULB_RS00520	COG0708	Exodeoxyribonuclease III
SULB_RS00525	COG0515	serine threonine protein kinase
SULB_RS00525	COG2815	serine threonine protein kinase
SULB_RS00590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SULB_RS00735	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
SULB_RS00740	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SULB_RS00755	COG0189	ligase activity
SULB_RS00795	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
SULB_RS00815	COG1053	succinate dehydrogenase
SULB_RS00835	COG2304	oxidoreductase activity
SULB_RS00840	COG0714	Associated with various cellular activities
SULB_RS00860	COG0083	homoserine kinase activity
SULB_RS00865	COG0626	cystathionine gamma-synthase activity
SULB_RS00905	COG0183	Belongs to the thiolase family
SULB_RS00910	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SULB_RS00955	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SULB_RS00965	COG0351	phosphomethylpyrimidine kinase
SULB_RS00970	COG0314	molybdopterin synthase activity
SULB_RS01005	COG1131	(ABC) transporter
SULB_RS01010	COG1668	transmembrane transport
SULB_RS01030	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SULB_RS01035	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SULB_RS01065	COG0720	synthase
SULB_RS01080	COG0492	ferredoxin-NADP+ reductase activity
SULB_RS01085	COG0483	inositol monophosphate 1-phosphatase activity
SULB_RS01090	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SULB_RS01105	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
SULB_RS01110	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SULB_RS01110	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SULB_RS01120	COG0071	Belongs to the small heat shock protein (HSP20) family
SULB_RS01180	COG0402	S-adenosylhomocysteine deaminase activity
SULB_RS01205	COG0430	RNA-3'-phosphate cyclase activity
SULB_RS01220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SULB_RS01225	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SULB_RS01235	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
SULB_RS01245	COG1515	deoxyribonuclease V activity
SULB_RS01290	COG4581	dead DEAH box helicase
SULB_RS01300	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SULB_RS01310	COG0439	Biotin carboxylase
SULB_RS01320	COG1116	anion transmembrane transporter activity
SULB_RS01325	COG0066	3-isopropylmalate dehydratase activity
SULB_RS01330	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SULB_RS01335	COG0415	Belongs to the DNA photolyase family
SULB_RS01390	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
SULB_RS01410	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SULB_RS01415	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SULB_RS01430	COG0045	succinate-CoA ligase (ADP-forming) activity
SULB_RS01500	COG1063	alcohol dehydrogenase
SULB_RS01505	COG0183	Belongs to the thiolase family
SULB_RS01510	COG1960	acyl-CoA dehydrogenase activity
SULB_RS01515	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SULB_RS01520	COG1028	Short-chain dehydrogenase reductase Sdr
SULB_RS01525	COG1064	alcohol dehydrogenase
SULB_RS01545	COG1309	transcriptional regulator
SULB_RS01570	COG0318	PFAM AMP-dependent synthetase and ligase
SULB_RS01575	COG1960	acyl-CoA dehydrogenase activity
SULB_RS01580	COG1024	Enoyl-CoA hydratase
SULB_RS01585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SULB_RS01590	COG0477	Major facilitator Superfamily
SULB_RS01615	COG0657	acetylesterase activity
SULB_RS01625	COG0318	PFAM AMP-dependent synthetase and ligase
SULB_RS01635	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SULB_RS01640	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
SULB_RS01645	COG0477	Major facilitator Superfamily
SULB_RS01665	COG0432	Pfam Uncharacterised protein family UPF0047
SULB_RS01675	COG1024	Enoyl-CoA hydratase
SULB_RS01685	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
SULB_RS01825	COG0477	Major facilitator Superfamily
SULB_RS01830	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SULB_RS01835	COG0778	Nitroreductase
SULB_RS01890	COG1489	DNA binding
SULB_RS01910	COG0750	zinc metalloprotease
SULB_RS01945	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SULB_RS01950	COG0039	L-malate dehydrogenase activity
SULB_RS01955	COG2079	MmgE PrpD family protein
SULB_RS01960	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
SULB_RS01965	COG0516	GMP reductase activity
SULB_RS01965	COG0517	IMP dehydrogenase activity
SULB_RS01970	COG0372	Belongs to the citrate synthase family
SULB_RS01985	COG0149	triose-phosphate isomerase activity
SULB_RS02015	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
SULB_RS02020	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SULB_RS02050	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SULB_RS02070	COG0438	transferase activity, transferring glycosyl groups
SULB_RS02085	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SULB_RS02090	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SULB_RS02100	COG4608	Belongs to the ABC transporter superfamily
SULB_RS02105	COG0444	Belongs to the ABC transporter superfamily
SULB_RS02110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SULB_RS02115	COG0601	transmembrane transport
SULB_RS02150	COG0183	Belongs to the thiolase family
SULB_RS02235	COG1592	Rubrerythrin
SULB_RS02260	COG4555	ABC transporter
SULB_RS02270	COG2217	Heavy metal translocating P-type atpase
SULB_RS02330	COG1028	Short-chain dehydrogenase reductase Sdr
SULB_RS02335	COG4948	Mandelate Racemase Muconate Lactonizing
SULB_RS02375	COG0444	Belongs to the ABC transporter superfamily
SULB_RS02380	COG4608	Belongs to the ABC transporter superfamily
SULB_RS02385	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SULB_RS02430	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SULB_RS02470	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SULB_RS02480	COG2239	Acts as a magnesium transporter
SULB_RS02485	COG0823	Involved in the tonB-independent uptake of proteins
SULB_RS02485	COG1506	peptidase
SULB_RS02485	COG4946	Tricorn protease homolog
SULB_RS02490	COG0501	Belongs to the peptidase M48B family
SULB_RS02495	COG4274	PFAM GYD family protein
SULB_RS02540	COG2814	Major facilitator Superfamily
SULB_RS02545	COG3386	PFAM SMP-30 Gluconolaconase
SULB_RS02550	COG0813	purine-nucleoside phosphorylase activity
SULB_RS02585	COG0395	ABC-type sugar transport system, permease component
SULB_RS02590	COG2814	Major facilitator Superfamily
SULB_RS02595	COG1063	alcohol dehydrogenase
SULB_RS02605	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SULB_RS02680	COG1573	uracil-dna glycosylase
SULB_RS02705	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SULB_RS02715	COG0517	IMP dehydrogenase activity
SULB_RS02725	COG3387	PFAM Glycoside hydrolase 15-related
SULB_RS02785	COG3387	PFAM Glycoside hydrolase 15-related
SULB_RS02790	COG0438	transferase activity, transferring glycosyl groups
SULB_RS02795	COG1013	pyruvate-flavodoxin oxidoreductase activity
SULB_RS02800	COG0674	pyruvate-flavodoxin oxidoreductase activity
SULB_RS02805	COG1144	Oxidoreductase
SULB_RS02810	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SULB_RS02815	COG0437	4 iron, 4 sulfur cluster binding
SULB_RS02830	COG1960	acyl-CoA dehydrogenase activity
SULB_RS02840	COG2086	electron transfer activity
SULB_RS02850	COG0492	ferredoxin-NADP+ reductase activity
SULB_RS02870	COG0668	transmembrane transport
SULB_RS02875	COG0402	S-adenosylhomocysteine deaminase activity
SULB_RS02890	COG3962	Belongs to the TPP enzyme family
SULB_RS02895	COG0438	transferase activity, transferring glycosyl groups
SULB_RS02905	COG0644	oxidoreductase
SULB_RS02915	COG0589	response to stress
SULB_RS02920	COG0656	L-ascorbic acid biosynthetic process
SULB_RS02970	COG0668	transmembrane transport
SULB_RS02975	COG0586	Pfam SNARE associated Golgi protein
SULB_RS02985	COG3511	phospholipase C
SULB_RS03010	COG0437	4 iron, 4 sulfur cluster binding
SULB_RS03015	COG0243	molybdopterin cofactor binding
SULB_RS03040	COG1063	alcohol dehydrogenase
SULB_RS03060	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SULB_RS03085	COG0318	PFAM AMP-dependent synthetase and ligase
SULB_RS03120	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SULB_RS03120	COG0674	pyruvate-flavodoxin oxidoreductase activity
SULB_RS03125	COG1013	pyruvate-flavodoxin oxidoreductase activity
SULB_RS03130	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
SULB_RS03135	COG0644	oxidoreductase
SULB_RS03145	COG0574	Belongs to the PEP-utilizing enzyme family
SULB_RS03145	COG3848	Pyruvate phosphate dikinase
SULB_RS03150	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
SULB_RS03160	COG3383	formate dehydrogenase (NAD+) activity
SULB_RS03200	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SULB_RS03250	COG0395	ABC-type sugar transport system, permease component
SULB_RS03255	COG3842	ATPase activity
SULB_RS03260	COG0477	Major facilitator Superfamily
SULB_RS03295	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SULB_RS03300	COG1584	GPR1 FUN34 yaaH family protein
SULB_RS03325	COG0281	malic enzyme
SULB_RS03335	COG1250	3-hydroxyacyl-CoA dehydrogenase
SULB_RS03350	COG0318	PFAM AMP-dependent synthetase and ligase
SULB_RS03355	COG1960	acyl-CoA dehydrogenase activity
SULB_RS03365	COG3608	succinylglutamate desuccinylase aspartoacylase
SULB_RS03365	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
SULB_RS03420	COG2217	Heavy metal translocating P-type atpase
SULB_RS03445	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
SULB_RS03445	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SULB_RS03455	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SULB_RS03495	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SULB_RS03615	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
SULB_RS03630	COG0477	Major facilitator Superfamily
SULB_RS03635	COG3473	Maleate cis-trans isomerase
SULB_RS03645	COG0179	Fumarylacetoacetate (FAA) hydrolase
SULB_RS03715	COG4608	Belongs to the ABC transporter superfamily
SULB_RS03720	COG0444	Belongs to the ABC transporter superfamily
SULB_RS03725	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SULB_RS03730	COG0601	transmembrane transport
SULB_RS03780	COG2857	Cytochrome c1
SULB_RS03780	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SULB_RS03795	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SULB_RS03815	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
SULB_RS03895	COG1914	H( )-stimulated, divalent metal cation uptake system
SULB_RS03900	COG1250	3-hydroxyacyl-CoA dehydrogenase
SULB_RS03905	COG4948	Mandelate Racemase Muconate Lactonizing
SULB_RS03910	COG0459	protein refolding
SULB_RS03925	COG1028	Short-chain dehydrogenase reductase Sdr
SULB_RS03940	COG0673	inositol 2-dehydrogenase activity
SULB_RS03960	COG1132	(ABC) transporter
SULB_RS03970	COG0667	Aldo Keto reductase
SULB_RS03995	COG2723	6-phospho-beta-galactosidase activity
SULB_RS04005	COG1501	Belongs to the glycosyl hydrolase 31 family
SULB_RS04055	COG1472	Belongs to the glycosyl hydrolase 3 family
SULB_RS04075	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SULB_RS04080	COG3250	beta-galactosidase activity
SULB_RS04100	COG3386	PFAM SMP-30 Gluconolaconase
SULB_RS04115	COG4608	Belongs to the ABC transporter superfamily
SULB_RS04120	COG0444	Belongs to the ABC transporter superfamily
SULB_RS04125	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SULB_RS04135	COG0673	inositol 2-dehydrogenase activity
SULB_RS04165	COG0667	Aldo Keto reductase
SULB_RS04215	COG0318	PFAM AMP-dependent synthetase and ligase
SULB_RS04230	COG0395	ABC-type sugar transport system, permease component
SULB_RS04235	COG3842	ATPase activity
SULB_RS04245	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SULB_RS04315	COG1136	(ABC) transporter
SULB_RS04335	COG0425	Belongs to the sulfur carrier protein TusA family
SULB_RS04375	COG1122	ATPase activity
SULB_RS04420	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
SULB_RS04435	COG0805	protein transport
SULB_RS04465	COG1028	Short-chain dehydrogenase reductase Sdr
SULB_RS04475	COG2267	carboxylic ester hydrolase activity
SULB_RS04485	COG0179	Fumarylacetoacetate (FAA) hydrolase
SULB_RS04490	COG2271	Major facilitator Superfamily
SULB_RS04505	COG4948	Mandelate Racemase Muconate Lactonizing
SULB_RS04530	COG2814	Major facilitator Superfamily
SULB_RS04535	COG1139	Iron-sulfur cluster binding protein
SULB_RS04545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SULB_RS04560	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SULB_RS04590	COG2271	Major facilitator Superfamily
SULB_RS04620	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SULB_RS04655	COG0655	NAD(P)H dehydrogenase (quinone) activity
SULB_RS04670	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SULB_RS04675	COG0095	Lipoate-protein ligase
SULB_RS04680	COG0247	lactate metabolic process
SULB_RS04685	COG0277	FAD linked oxidase domain protein
SULB_RS04725	COG1720	tRNA m6t6A37 methyltransferase activity
SULB_RS04740	COG0517	IMP dehydrogenase activity
SULB_RS04740	COG0516	GMP reductase activity
SULB_RS04750	COG1733	regulation of RNA biosynthetic process
SULB_RS04770	COG2814	Major facilitator Superfamily
SULB_RS04780	COG0515	serine threonine protein kinase
SULB_RS04780	COG2815	serine threonine protein kinase
SULB_RS04785	COG0589	response to stress
SULB_RS04790	COG0833	amino acid
SULB_RS04820	COG0243	molybdopterin cofactor binding
SULB_RS04825	COG0530	calcium, potassium:sodium antiporter activity
SULB_RS04830	COG1012	belongs to the aldehyde dehydrogenase family
SULB_RS04840	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SULB_RS04845	COG4948	Mandelate Racemase Muconate Lactonizing
SULB_RS04860	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SULB_RS04870	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SULB_RS04875	COG1063	alcohol dehydrogenase
SULB_RS04880	COG0517	IMP dehydrogenase activity
SULB_RS04880	COG0516	GMP reductase activity
SULB_RS04900	COG0656	L-ascorbic acid biosynthetic process
SULB_RS04915	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SULB_RS04930	COG1444	tRNA N-acetyltransferase activity
SULB_RS04945	COG0405	Gamma-glutamyltransferase
SULB_RS04980	COG1830	Aldolase
SULB_RS04990	COG0517	IMP dehydrogenase activity
SULB_RS04990	COG0516	GMP reductase activity
SULB_RS04995	COG0501	Belongs to the peptidase M48B family
SULB_RS05000	COG0519	Catalyzes the synthesis of GMP from XMP
SULB_RS05000	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SULB_RS05010	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
SULB_RS05020	COG1063	alcohol dehydrogenase
SULB_RS05040	COG0463	Glycosyl transferase, family 2
SULB_RS05090	COG1215	transferase activity, transferring glycosyl groups
SULB_RS05100	COG0352	thiamine-phosphate diphosphorylase activity
SULB_RS05100	COG0351	phosphomethylpyrimidine kinase
SULB_RS05105	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SULB_RS05125	COG0123	including yeast histone deacetylase and acetoin utilization protein
SULB_RS05140	COG2860	membrane
SULB_RS05165	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
SULB_RS05175	COG1201	RNA secondary structure unwinding
SULB_RS05220	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
SULB_RS05230	COG3620	sequence-specific DNA binding
SULB_RS05230	COG0617	tRNA 3'-terminal CCA addition
SULB_RS05230	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SULB_RS05250	COG1192	Involved in chromosome partitioning
SULB_RS05345	COG1131	(ABC) transporter
SULB_RS05400	COG1304	FMN binding
SULB_RS05415	COG1355	regulation of microtubule-based process
SULB_RS05420	COG0052	Belongs to the universal ribosomal protein uS2 family
SULB_RS05430	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SULB_RS05435	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SULB_RS05440	COG0200	Binds to the 23S rRNA
SULB_RS05450	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SULB_RS05455	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SULB_RS05460	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SULB_RS05475	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SULB_RS05490	COG0456	acetyltransferase
SULB_RS05490	COG1214	PFAM Peptidase M22, glycoprotease
SULB_RS05515	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SULB_RS05520	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SULB_RS05535	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SULB_RS05540	COG0561	phosphatase activity
SULB_RS05545	COG1078	dGTPase activity
SULB_RS05570	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SULB_RS05585	COG2267	carboxylic ester hydrolase activity
SULB_RS05590	COG1058	Belongs to the CinA family
SULB_RS05590	COG1546	Belongs to the CinA family
SULB_RS05595	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SULB_RS05620	COG0617	tRNA 3'-terminal CCA addition
SULB_RS05620	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SULB_RS05620	COG0517	IMP dehydrogenase activity
SULB_RS05625	COG1201	RNA secondary structure unwinding
SULB_RS05640	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SULB_RS05695	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SULB_RS05800	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
SULB_RS05845	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SULB_RS05850	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SULB_RS05865	COG0189	ligase activity
SULB_RS05870	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SULB_RS05875	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SULB_RS05880	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SULB_RS05905	COG1129	ABC transporter
SULB_RS05920	COG0028	Belongs to the TPP enzyme family
SULB_RS05935	COG0017	Asparaginyl-tRNA synthetase
SULB_RS05940	COG0585	pseudouridine synthase activity
SULB_RS05960	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SULB_RS05975	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SULB_RS05975	COG1648	precorrin-2 dehydrogenase activity
SULB_RS05980	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
SULB_RS05985	COG0113	porphobilinogen synthase activity
SULB_RS05990	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SULB_RS05995	COG0181	hydroxymethylbilane synthase activity
SULB_RS06020	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SULB_RS06030	COG1793	dna ligase
SULB_RS06035	COG0717	Belongs to the dCTP deaminase family
SULB_RS06080	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
SULB_RS06095	COG0504	CTP synthase activity
SULB_RS06100	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
SULB_RS06120	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SULB_RS06130	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SULB_RS06135	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
SULB_RS06175	COG0051	transcription antitermination factor activity, RNA binding
SULB_RS06180	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SULB_RS06185	COG0049	tRNA binding
SULB_RS06210	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SULB_RS06215	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SULB_RS06220	COG0085	RNA polymerase activity
SULB_RS06250	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SULB_RS06255	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SULB_RS06270	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SULB_RS06285	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SULB_RS06300	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SULB_RS06315	COG0077	Prephenate dehydratase
SULB_RS06315	COG1605	Chorismate mutase
SULB_RS06340	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
SULB_RS06340	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SULB_RS06355	COG1051	belongs to the nudix hydrolase family
SULB_RS06355	COG1056	cytidyltransferase-related domain
SULB_RS06390	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SULB_RS06430	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SULB_RS06440	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SULB_RS06455	COG0343	queuine tRNA-ribosyltransferase activity
SULB_RS06475	COG0124	histidyl-tRNA synthetase
SULB_RS06490	COG0459	protein refolding
SULB_RS06515	COG1980	fructose-bisphosphate aldolase activity
SULB_RS06520	COG1121	(ABC) transporter
SULB_RS06530	COG0477	Major facilitator Superfamily
SULB_RS06555	COG1185	polyribonucleotide nucleotidyltransferase activity
SULB_RS06565	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SULB_RS06585	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SULB_RS06590	COG3959	Transketolase, thiamine diphosphate binding domain
SULB_RS06595	COG3958	Transketolase
SULB_RS06600	COG0077	Prephenate dehydratase
SULB_RS06600	COG1605	Chorismate mutase
SULB_RS06605	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
SULB_RS06610	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SULB_RS06615	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SULB_RS06620	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SULB_RS06630	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SULB_RS06650	COG1199	ATP-dependent helicase activity
SULB_RS06670	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SULB_RS06675	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SULB_RS06705	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SULB_RS06710	COG0649	NAD binding
SULB_RS06715	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SULB_RS06720	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SULB_RS06730	COG0713	ATP synthesis coupled electron transport
SULB_RS06735	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SULB_RS06740	COG1007	ATP synthesis coupled electron transport
SULB_RS06745	COG1260	myo-inositol-1-phosphate synthase
SULB_RS06750	COG0301	tRNA thio-modification
SULB_RS06780	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SULB_RS06790	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SULB_RS06800	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SULB_RS06815	COG0552	protein localization to endoplasmic reticulum
SULB_RS06880	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SULB_RS06895	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SULB_RS06905	COG0302	gtp cyclohydrolase
SULB_RS06925	COG3118	belongs to the thioredoxin family
SULB_RS06930	COG0318	PFAM AMP-dependent synthetase and ligase
SULB_RS06945	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
SULB_RS06950	COG0535	radical SAM domain protein
SULB_RS06960	COG0475	glutathione-regulated potassium exporter activity
SULB_RS06990	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SULB_RS07005	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SULB_RS07010	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SULB_RS07030	COG0438	transferase activity, transferring glycosyl groups
SULB_RS07055	COG1444	tRNA N-acetyltransferase activity
SULB_RS07065	COG2813	Specifically methylates the guanine in position
SULB_RS07070	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SULB_RS07075	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SULB_RS07085	COG1201	RNA secondary structure unwinding
SULB_RS07105	COG0402	S-adenosylhomocysteine deaminase activity
SULB_RS07115	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SULB_RS07135	COG1797	cobyrinic acid a,c-diamide synthase activity
SULB_RS07150	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
SULB_RS07180	COG0539	negative regulation of cytoplasmic translation
SULB_RS07195	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
SULB_RS07200	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SULB_RS07205	COG1110	DNA topoisomerase II activity
SULB_RS07230	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SULB_RS07250	COG0667	Aldo Keto reductase
SULB_RS07255	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SULB_RS07265	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SULB_RS07275	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
SULB_RS07280	COG0163	prenyltransferase activity
SULB_RS07310	COG0423	glycine-tRNA ligase activity
SULB_RS07315	COG0010	Belongs to the arginase family
SULB_RS07350	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SULB_RS07360	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SULB_RS07390	COG1280	lysine exporter protein (LysE YggA)
SULB_RS07410	COG0489	protein tyrosine kinase activity
SULB_RS07450	COG1992	Thiamine-phosphate synthase
SULB_RS07450	COG0351	phosphomethylpyrimidine kinase
SULB_RS07470	COG3276	selenocysteine insertion sequence binding
SULB_RS07480	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
SULB_RS07485	COG0556	nucleotide-excision repair
SULB_RS07495	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SULB_RS07515	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SULB_RS07520	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SULB_RS07530	COG0805	protein transport
SULB_RS07540	COG4139	cobalamin transport
SULB_RS07545	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
SULB_RS07550	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SULB_RS07565	COG0581	inorganic phosphate transmembrane transporter activity
SULB_RS07590	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SULB_RS07640	COG0495	leucyl-tRNA aminoacylation
SULB_RS07935	COG0433	COG0433 Predicted ATPase
SULB_RS08035	COG4974	Belongs to the 'phage' integrase family
SULB_RS08080	COG0535	radical SAM domain protein
SULB_RS08100	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
SULB_RS08150	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
SULB_RS08155	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SULB_RS08175	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SULB_RS08180	COG0589	response to stress
SULB_RS08190	COG0126	phosphoglycerate kinase activity
SULB_RS08200	COG0668	transmembrane transport
SULB_RS08225	COG0417	DNA replication proofreading
SULB_RS08255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SULB_RS08275	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
SULB_RS08285	COG1394	ATPase activity, coupled to movement of substances
SULB_RS08300	COG0442	prolyl-tRNA aminoacylation
SULB_RS08310	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
SULB_RS08315	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
SULB_RS08330	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SULB_RS08340	COG0028	Belongs to the TPP enzyme family
SULB_RS08350	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SULB_RS08360	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SULB_RS08375	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
SULB_RS08385	COG0037	tRNA processing
SULB_RS08390	COG2096	Adenosyltransferase
SULB_RS08395	COG0495	leucyl-tRNA aminoacylation
SULB_RS08405	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SULB_RS08410	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SULB_RS08415	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SULB_RS08420	COG0131	Imidazoleglycerol-phosphate dehydratase
SULB_RS08425	COG0107	imidazoleglycerol-phosphate synthase activity
SULB_RS08430	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SULB_RS08435	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SULB_RS08435	COG0140	phosphoribosyl-ATP diphosphatase activity
SULB_RS08440	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SULB_RS08450	COG2151	metal-sulfur cluster biosynthetic enzyme
SULB_RS08455	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SULB_RS08460	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SULB_RS08475	COG1522	sequence-specific DNA binding
SULB_RS08480	COG2095	MarC family integral membrane protein
SULB_RS08495	COG0167	dihydroorotate dehydrogenase activity
SULB_RS08510	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
SULB_RS08520	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SULB_RS08560	COG0602	queuosine metabolic process
SULB_RS08565	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SULB_RS08570	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SULB_RS08570	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SULB_RS08575	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SULB_RS08585	COG0047	phosphoribosylformylglycinamidine synthase activity
SULB_RS08590	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SULB_RS08595	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
SULB_RS08600	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
SULB_RS08610	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SULB_RS08625	COG0137	argininosuccinate synthase activity
SULB_RS08630	COG0165	Argininosuccinate lyase
SULB_RS08645	COG0189	ligase activity
SULB_RS08655	COG1250	3-hydroxyacyl-CoA dehydrogenase
SULB_RS08685	COG1024	Enoyl-CoA hydratase
SULB_RS08700	COG0460	homoserine dehydrogenase
SULB_RS08710	COG0864	Transcriptional regulator
SULB_RS08715	COG0312	modulator of DNA gyrase
SULB_RS08720	COG0312	modulator of DNA gyrase
SULB_RS08725	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
SULB_RS08725	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
SULB_RS08730	COG0009	L-threonylcarbamoyladenylate synthase
SULB_RS08735	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SULB_RS08740	COG2379	hydroxypyruvate reductase
SULB_RS08750	COG1321	iron dependent repressor
SULB_RS08780	COG1763	Mo-molybdopterin cofactor biosynthetic process
SULB_RS08785	COG0303	'Molybdopterin
SULB_RS08800	COG0402	S-adenosylhomocysteine deaminase activity
SULB_RS08815	COG0067	glutamate synthase
SULB_RS08820	COG0069	glutamate synthase activity
SULB_RS08830	COG1136	(ABC) transporter
SULB_RS08830	COG0577	efflux transmembrane transporter activity
SULB_RS08840	COG1136	(ABC) transporter
SULB_RS08905	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SULB_RS08925	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SULB_RS08930	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SULB_RS08940	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SULB_RS08950	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SULB_RS08955	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SULB_RS08960	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SULB_RS08970	COG0255	Belongs to the universal ribosomal protein uL29 family
SULB_RS08975	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SULB_RS08980	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SULB_RS08985	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SULB_RS08990	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SULB_RS09005	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SULB_RS09020	COG0473	3-isopropylmalate dehydrogenase activity
SULB_RS09040	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SULB_RS09045	COG0322	excinuclease ABC activity
SULB_RS09075	COG1185	polyribonucleotide nucleotidyltransferase activity
SULB_RS09120	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SULB_RS09130	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
SULB_RS09135	COG2264	protein methyltransferase activity
SULB_RS09140	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SULB_RS09175	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
SULB_RS09190	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
SULB_RS09205	COG1047	Peptidyl-prolyl cis-trans
SULB_RS09210	COG0371	Dehydrogenase
SULB_RS09215	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
SULB_RS09250	COG1063	alcohol dehydrogenase
SULB_RS09255	COG0154	amidase activity
SULB_RS09260	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SULB_RS09265	COG1881	PFAM PEBP family protein
SULB_RS09275	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SULB_RS09280	COG0315	cyclic pyranopterin monophosphate synthase activity
SULB_RS09325	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
SULB_RS09340	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SULB_RS09395	COG0459	protein refolding
SULB_RS09430	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SULB_RS09450	COG0460	homoserine dehydrogenase
SULB_RS09450	COG0527	aspartate kinase activity
SULB_RS09455	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SULB_RS09475	COG0574	Belongs to the PEP-utilizing enzyme family
SULB_RS09475	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SULB_RS09480	COG1260	myo-inositol-1-phosphate synthase
SULB_RS09485	COG1254	Belongs to the acylphosphatase family
SULB_RS09490	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
SULB_RS09495	COG0159	tryptophan synthase activity
SULB_RS09505	COG0135	phosphoribosylanthranilate isomerase activity
SULB_RS09510	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SULB_RS09515	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SULB_RS09515	COG0512	Glutamine amidotransferase of anthranilate synthase
SULB_RS09525	COG0436	Aminotransferase
SULB_RS09530	COG0525	valine-tRNA ligase activity
SULB_RS09535	COG0644	oxidoreductase
SULB_RS09565	COG1059	Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites)
SULB_RS09570	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SULB_RS09585	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SULB_RS09590	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SULB_RS09610	COG0148	phosphopyruvate hydratase activity
SULB_RS09630	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SULB_RS09640	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SULB_RS09645	COG0509	glycine decarboxylation via glycine cleavage system
SULB_RS09665	COG0396	ATPase activity
SULB_RS09670	COG0719	Fe-S assembly protein
SULB_RS09675	COG1372	Participates in initiation and elongation during chromosome replication
SULB_RS09675	COG0719	Fe-S assembly protein
SULB_RS09690	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SULB_RS09705	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SULB_RS09710	COG0252	asparaginase activity
SULB_RS09740	COG1867	N(2),N(2)-dimethylguanosine tRNA methyltransferase
SULB_RS09795	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SULB_RS09795	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
SULB_RS09810	COG0154	amidase activity
SULB_RS09850	COG1110	DNA topoisomerase II activity
SULB_RS09880	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SULB_RS09890	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SULB_RS09895	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SULB_RS09910	COG1028	Short-chain dehydrogenase reductase Sdr
SULB_RS09920	COG0528	UMP kinase activity
SULB_RS09930	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SULB_RS09950	COG0469	pyruvate kinase activity
SULB_RS09960	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SULB_RS09970	COG0297	glycogen (starch) synthase activity
SULB_RS09980	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SULB_RS10010	COG0157	Belongs to the NadC ModD family
SULB_RS10015	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SULB_RS10020	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
SULB_RS10035	COG0395	ABC-type sugar transport system, permease component
SULB_RS10055	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SULB_RS10070	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SULB_RS10075	COG0028	Belongs to the TPP enzyme family
SULB_RS10090	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
SULB_RS10095	COG2897	thiosulfate sulfurtransferase activity
SULB_RS10105	COG0651	ATP synthesis coupled electron transport
SULB_RS10110	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SULB_RS10115	COG0649	NAD binding
SULB_RS10120	COG0651	ATP synthesis coupled electron transport
SULB_RS10130	COG0650	Formate hydrogenlyase subunit 4
SULB_RS10145	COG3383	formate dehydrogenase (NAD+) activity
SULB_RS10150	COG0300	oxidoreductase activity
SULB_RS10155	COG0725	ABC transporter, periplasmic molybdate-binding protein
SULB_RS10160	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
SULB_RS10205	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
SULB_RS10220	COG1234	tRNA 3'-trailer cleavage
SULB_RS10265	COG1185	polyribonucleotide nucleotidyltransferase activity
SULB_RS10280	COG0004	ammonium transporteR
SULB_RS10315	COG0095	Lipoate-protein ligase
SULB_RS10320	COG0509	glycine decarboxylation via glycine cleavage system
SULB_RS10340	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SULB_RS10345	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
SULB_RS10350	COG2005	Transcriptional regulator
SULB_RS10365	COG0531	amino acid
SULB_RS10395	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SULB_RS10395	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SULB_RS10400	COG0517	IMP dehydrogenase activity
SULB_RS10410	COG0114	fumarate hydratase activity
SULB_RS10415	COG1136	(ABC) transporter
SULB_RS10425	COG1136	(ABC) transporter
SULB_RS10425	COG0577	efflux transmembrane transporter activity
SULB_RS10430	COG1846	Transcriptional regulator
SULB_RS10435	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
SULB_RS10440	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
SULB_RS10485	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
SULB_RS10525	COG2271	Major facilitator Superfamily
SULB_RS10535	COG0509	glycine decarboxylation via glycine cleavage system
SULB_RS10565	COG1832	CoA-binding protein
SULB_RS10570	COG0095	Lipoate-protein ligase
SULB_RS10615	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SULB_RS10625	COG2210	Belongs to the sulfur carrier protein TusA family
SULB_RS10630	COG0425	Belongs to the sulfur carrier protein TusA family
SULB_RS10660	COG2048	Heterodisulfide reductase, subunit B
SULB_RS10675	COG0475	glutathione-regulated potassium exporter activity
SULB_RS10705	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
SULB_RS10710	COG0477	Major facilitator Superfamily
SULB_RS10750	COG1960	acyl-CoA dehydrogenase activity
SULB_RS10790	COG2814	Major facilitator Superfamily
SULB_RS10810	COG3842	ATPase activity
SULB_RS10815	COG3833	ABC-type maltose transport systems, permease component
SULB_RS10820	COG1175	transmembrane transport
SULB_RS10855	COG0436	Aminotransferase
SULB_RS10890	COG2271	Major facilitator Superfamily
SULB_RS10895	COG1335	isochorismatase
SULB_RS10940	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SULB_RS10945	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SULB_RS10955	COG2062	phosphohistidine phosphatase, SixA
SULB_RS11010	COG1013	pyruvate-flavodoxin oxidoreductase activity
SULB_RS11015	COG0674	pyruvate-flavodoxin oxidoreductase activity
SULB_RS11050	COG0277	FAD linked oxidase domain protein
SULB_RS11090	COG3608	succinylglutamate desuccinylase aspartoacylase
SULB_RS11090	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
SULB_RS11130	COG3350	monooxygenase activity
SULB_RS11155	COG2151	metal-sulfur cluster biosynthetic enzyme
SULB_RS11215	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
SULB_RS11215	COG2050	protein possibly involved in aromatic compounds catabolism
SULB_RS11220	COG2301	Belongs to the HpcH HpaI aldolase family
SULB_RS11225	COG1802	Transcriptional regulator
SULB_RS11240	COG2721	sulfolactate sulfo-lyase activity
SULB_RS11245	COG2721	sulfolactate sulfo-lyase activity
SULB_RS11265	COG1131	(ABC) transporter
SULB_RS11270	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SULB_RS11285	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SULB_RS11300	COG0601	transmembrane transport
SULB_RS11310	COG0444	Belongs to the ABC transporter superfamily
SULB_RS11315	COG4608	Belongs to the ABC transporter superfamily
SULB_RS11330	COG4608	Belongs to the ABC transporter superfamily
SULB_RS11335	COG0444	Belongs to the ABC transporter superfamily
SULB_RS11345	COG0601	transmembrane transport
SULB_RS11370	COG1373	ATPase (AAA superfamily
SULB_RS11415	COG1215	transferase activity, transferring glycosyl groups
SULB_RS11445	COG4948	Mandelate Racemase Muconate Lactonizing
SULB_RS11465	COG2814	Major facilitator Superfamily
SULB_RS11555	COG1203	CRISPR-associated helicase, Cas3
SULB_RS11605	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
SULB_RS11630	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SULB_RS11665	COG0531	amino acid
SULB_RS11675	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
SULB_RS11695	COG1373	ATPase (AAA superfamily
SULB_RS11910	COG0813	purine-nucleoside phosphorylase activity
SULB_RS11940	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SULB_RS11945	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SULB_RS11950	COG0022	dehydrogenase e1 component
SULB_RS11955	COG3199	ATP-NAD kinase
SULB_RS11960	COG0508	dehydrogenase complex catalyzes the overall conversion of
SULB_RS11965	COG0277	FAD linked oxidase domain protein
SULB_RS11970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SULB_RS11975	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
SULB_RS12000	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SULB_RS12005	COG0477	Major facilitator Superfamily
SULB_RS12080	COG2084	Dehydrogenase
SULB_RS12095	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SULB_RS12160	COG0243	molybdopterin cofactor binding
SULB_RS12220	COG1725	Transcriptional regulator
SULB_RS12310	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SULB_RS12315	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SULB_RS12320	COG4279	zinc finger
SULB_RS12365	COG1953	Uracil, thiamine, allantoin
SULB_RS12510	COG0531	amino acid
SULB_RS12520	COG3335	DDE superfamily endonuclease
SULB_RS12590	COG0438	transferase activity, transferring glycosyl groups
SULB_RS12760	COG1215	transferase activity, transferring glycosyl groups
SULB_RS12765	COG1442	glycosyl transferase family 8
SULB_RS12765	COG1216	Glycosyl transferase, family 2
SULB_RS12775	COG0463	Glycosyl transferase, family 2
SULB_RS12775	COG1216	Glycosyl transferase, family 2
SULB_RS12890	COG2002	toxin-antitoxin pair type II binding
SULB_RS12955	COG0425	Belongs to the sulfur carrier protein TusA family
SULB_RS13125	COG1136	(ABC) transporter
SULB_RS13125	COG0577	efflux transmembrane transporter activity
SULB_RS13180	COG2151	metal-sulfur cluster biosynthetic enzyme
SULB_RS13185	COG0589	response to stress
SULB_RS13205	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
SULB_RS13215	COG0501	Belongs to the peptidase M48B family
SULB_RS13225	COG0519	Catalyzes the synthesis of GMP from XMP
SULB_RS13270	COG0535	radical SAM domain protein
SULB_RS13275	COG0535	radical SAM domain protein
SULB_RS13395	COG2897	thiosulfate sulfurtransferase activity
SULB_RS13525	COG0513	Belongs to the DEAD box helicase family
SULB_RS13555	COG1011	Hydrolase
SULB_RS13560	COG4106	trans-aconitate 2-methyltransferase activity
SULB_RS13610	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SULB_RS13615	COG1953	Uracil, thiamine, allantoin
SULB_RS13620	COG0531	amino acid
SULB_RS13625	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SULB_RS13635	COG2814	Major facilitator Superfamily
SULB_RS13785	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SULB_RS13805	COG1131	(ABC) transporter
SULB_RS13830	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
SULB_RS13835	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SULB_RS13885	COG1473	amidohydrolase
SULB_RS14000	COG1960	acyl-CoA dehydrogenase activity
SULB_RS14010	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SULB_RS14040	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SULB_RS14045	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SULB_RS14050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SULB_RS14085	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SULB_RS14085	COG2146	nitrite reductase [NAD(P)H] activity
SULB_RS14105	COG0412	Dienelactone hydrolase
SULB_RS14155	COG0793	Belongs to the peptidase S41A family
SULB_RS14155	COG4946	Tricorn protease homolog
SULB_RS14160	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SULB_RS14265	COG1121	(ABC) transporter
SULB_RS14280	COG1305	Transglutaminase-like
SULB_RS14285	COG0450	alkyl hydroperoxide reductase
SULB_RS14315	COG1620	l-lactate permease
SULB_RS14340	COG0674	pyruvate-flavodoxin oxidoreductase activity
SULB_RS14345	COG1013	pyruvate-flavodoxin oxidoreductase activity
SULB_RS14350	COG1522	sequence-specific DNA binding
SULB_RS14365	COG0477	Major facilitator Superfamily
SULB_RS14375	COG1131	(ABC) transporter
SULB_RS14470	COG0561	phosphatase activity
SULB_RS14475	COG2264	protein methyltransferase activity
SULB_RS14480	COG1011	Hydrolase
SULB_RS14495	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SULB_RS14530	COG0494	nUDIX hydrolase
SULB_RS14540	COG3253	May function as heme-dependent peroxidase
SULB_RS14555	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SULB_RS14560	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SULB_RS14560	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SULB_RS14590	COG2226	methyltransferase
SULB_RS14845	COG1131	(ABC) transporter
SULB_RS15065	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
SULB_RS15120	COG0675	Transposase, IS605 OrfB family
SULB_RS15255	COG0275	rRNA processing