locus-tag	class	description
FQU85_RS00035	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FQU85_RS00070	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
FQU85_RS00110	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FQU85_RS00145	COG0318	PFAM AMP-dependent synthetase and ligase
FQU85_RS00155	COG2030	dehydratase
FQU85_RS00185	COG1294	oxidase, subunit
FQU85_RS00195	COG0450	alkyl hydroperoxide reductase
FQU85_RS00200	COG2897	thiosulfate sulfurtransferase activity
FQU85_RS00205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FQU85_RS00205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FQU85_RS00210	COG0730	response to heat
FQU85_RS00235	COG2132	Multicopper oxidase
FQU85_RS00245	COG3118	belongs to the thioredoxin family
FQU85_RS00255	COG3118	belongs to the thioredoxin family
FQU85_RS00280	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FQU85_RS00285	COG0446	pyridine nucleotide-disulphide oxidoreductase
FQU85_RS00300	COG3118	belongs to the thioredoxin family
FQU85_RS00310	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FQU85_RS00310	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FQU85_RS00320	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FQU85_RS00320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FQU85_RS00325	COG2226	methyltransferase
FQU85_RS00340	COG0730	response to heat
FQU85_RS00355	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FQU85_RS00355	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FQU85_RS00360	COG0425	Belongs to the sulfur carrier protein TusA family
FQU85_RS00370	COG2210	Belongs to the sulfur carrier protein TusA family
FQU85_RS00390	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FQU85_RS00395	COG2202	Pas domain
FQU85_RS00395	COG1366	Belongs to the anti-sigma-factor antagonist family
FQU85_RS00400	COG1271	oxidase subunit
FQU85_RS00425	COG0589	response to stress
FQU85_RS00440	COG0589	response to stress
FQU85_RS00465	COG3842	ATPase activity
FQU85_RS00530	COG1518	maintenance of DNA repeat elements
FQU85_RS00535	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FQU85_RS00545	COG2205	protein histidine kinase activity
FQU85_RS00550	COG0745	RESPONSE REGULATOR receiver
FQU85_RS00600	COG0534	Mate efflux family protein
FQU85_RS00715	COG1252	NADH dehydrogenase
FQU85_RS00720	COG0247	lactate metabolic process
FQU85_RS00720	COG0277	FAD linked oxidase domain protein
FQU85_RS00725	COG2414	aldehyde ferredoxin oxidoreductase
FQU85_RS00875	COG1074	ATP-dependent DNA helicase activity
FQU85_RS00895	COG1366	Belongs to the anti-sigma-factor antagonist family
FQU85_RS00895	COG2202	Pas domain
FQU85_RS00920	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
FQU85_RS00930	COG1366	Belongs to the anti-sigma-factor antagonist family
FQU85_RS00930	COG2202	Pas domain
FQU85_RS01005	COG1192	Involved in chromosome partitioning
FQU85_RS01035	COG0473	3-isopropylmalate dehydrogenase activity
FQU85_RS01040	COG0066	3-isopropylmalate dehydratase activity
FQU85_RS01045	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FQU85_RS01055	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FQU85_RS01065	COG0028	Belongs to the TPP enzyme family
FQU85_RS01070	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FQU85_RS01080	COG1733	regulation of RNA biosynthetic process
FQU85_RS01095	COG0745	RESPONSE REGULATOR receiver
FQU85_RS01135	COG4555	ABC transporter
FQU85_RS01180	COG2217	Heavy metal translocating P-type atpase
FQU85_RS01215	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FQU85_RS01255	COG0644	oxidoreductase
FQU85_RS01265	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FQU85_RS01305	COG0560	Phosphoserine phosphatase
FQU85_RS01305	COG3830	Belongs to the UPF0237 family
FQU85_RS01340	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FQU85_RS01405	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FQU85_RS01410	COG0442	prolyl-tRNA aminoacylation
FQU85_RS01415	COG0069	glutamate synthase activity
FQU85_RS01415	COG0067	glutamate synthase
FQU85_RS01415	COG0070	glutamate synthase
FQU85_RS01425	COG0371	Dehydrogenase
FQU85_RS01430	COG1505	serine-type exopeptidase activity
FQU85_RS01445	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FQU85_RS01460	COG1960	acyl-CoA dehydrogenase activity
FQU85_RS01465	COG0471	metal ion transport
FQU85_RS01480	COG0019	diaminopimelate decarboxylase activity
FQU85_RS01485	COG2171	N-acyltransferase activity
FQU85_RS01490	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FQU85_RS01495	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FQU85_RS01530	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FQU85_RS01535	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FQU85_RS01540	COG1830	Aldolase
FQU85_RS01550	COG1250	3-hydroxyacyl-CoA dehydrogenase
FQU85_RS01565	COG1960	acyl-CoA dehydrogenase activity
FQU85_RS01575	COG0183	Belongs to the thiolase family
FQU85_RS01595	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FQU85_RS01595	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FQU85_RS01610	COG1131	(ABC) transporter
FQU85_RS01615	COG0109	protoheme IX farnesyltransferase activity
FQU85_RS01620	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FQU85_RS01625	COG0702	epimerase
FQU85_RS01655	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FQU85_RS01675	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FQU85_RS01675	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FQU85_RS01680	COG1125	glycine betaine transport
FQU85_RS01680	COG0517	IMP dehydrogenase activity
FQU85_RS01685	COG1227	inorganic diphosphatase activity
FQU85_RS01690	COG1007	ATP synthesis coupled electron transport
FQU85_RS01695	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FQU85_RS01705	COG0713	ATP synthesis coupled electron transport
FQU85_RS01730	COG0649	NAD binding
FQU85_RS01730	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FQU85_RS01730	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FQU85_RS01735	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FQU85_RS01740	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FQU85_RS01745	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FQU85_RS01750	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FQU85_RS01760	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FQU85_RS01770	COG2431	L-lysine efflux transmembrane transporter activity
FQU85_RS01775	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FQU85_RS01790	COG0616	signal peptide processing
FQU85_RS01825	COG0512	Glutamine amidotransferase of anthranilate synthase
FQU85_RS01825	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FQU85_RS01830	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FQU85_RS01840	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FQU85_RS01850	COG1234	tRNA 3'-trailer cleavage
FQU85_RS01880	COG1960	acyl-CoA dehydrogenase activity
FQU85_RS01895	COG1546	Belongs to the CinA family
FQU85_RS01895	COG1058	Belongs to the CinA family
FQU85_RS01905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FQU85_RS01920	COG0003	Pfam Anion-transporting ATPase
FQU85_RS01930	COG0300	oxidoreductase activity
FQU85_RS01935	COG1515	deoxyribonuclease V activity
FQU85_RS01950	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FQU85_RS01950	COG1796	DNA polymerase
FQU85_RS02010	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FQU85_RS02020	COG1196	nuclear chromosome segregation
FQU85_RS02035	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FQU85_RS02065	COG1073	alpha beta
FQU85_RS02070	COG0384	phenazine biosynthesis protein PhzF
FQU85_RS02080	COG0574	Belongs to the PEP-utilizing enzyme family
FQU85_RS02080	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FQU85_RS02085	COG0076	glutamate decarboxylase activity
FQU85_RS02100	COG0697	spore germination
FQU85_RS02105	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FQU85_RS02105	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FQU85_RS02115	COG0469	pyruvate kinase activity
FQU85_RS02125	COG0330	HflC and HflK could
FQU85_RS02160	COG0463	Glycosyl transferase, family 2
FQU85_RS02165	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FQU85_RS02180	COG0710	3-dehydroquinate dehydratase activity
FQU85_RS02190	COG0134	indole-3-glycerol-phosphate synthase activity
FQU85_RS02195	COG0133	tryptophan synthase activity
FQU85_RS02200	COG0159	tryptophan synthase activity
FQU85_RS02210	COG1465	3-dehydroquinate synthase
FQU85_RS02230	COG0470	DNA polymerase III
FQU85_RS02230	COG1067	ATP-dependent peptidase activity
FQU85_RS02245	COG2860	membrane
FQU85_RS02260	COG0459	protein refolding
FQU85_RS02275	COG2226	methyltransferase
FQU85_RS02315	COG0494	nUDIX hydrolase
FQU85_RS02325	COG1215	transferase activity, transferring glycosyl groups
FQU85_RS02380	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FQU85_RS02390	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FQU85_RS02440	COG0717	Belongs to the dCTP deaminase family
FQU85_RS02450	COG0585	pseudouridine synthase activity
FQU85_RS02455	COG0346	lactoylglutathione lyase activity
FQU85_RS02510	COG0579	oxidoreductase
FQU85_RS02520	COG0714	Associated with various cellular activities
FQU85_RS02545	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FQU85_RS02590	COG2894	cell division
FQU85_RS02700	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FQU85_RS02720	COG4106	trans-aconitate 2-methyltransferase activity
FQU85_RS02725	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FQU85_RS02735	COG0095	Lipoate-protein ligase
FQU85_RS02765	COG1253	flavin adenine dinucleotide binding
FQU85_RS02770	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FQU85_RS02780	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FQU85_RS02785	COG3118	belongs to the thioredoxin family
FQU85_RS02790	COG1278	Cold shock
FQU85_RS02795	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FQU85_RS02800	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FQU85_RS02805	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
FQU85_RS02810	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FQU85_RS02820	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FQU85_RS02825	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FQU85_RS02835	COG0277	FAD linked oxidase domain protein
FQU85_RS02860	COG0579	oxidoreductase
FQU85_RS02865	COG1312	Catalyzes the dehydration of D-mannonate
FQU85_RS02870	COG4948	Mandelate Racemase Muconate Lactonizing
FQU85_RS02900	COG0427	acetyl-CoA hydrolase
FQU85_RS02905	COG1960	acyl-CoA dehydrogenase activity
FQU85_RS02920	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FQU85_RS02985	COG0501	Belongs to the peptidase M48B family
FQU85_RS03015	COG0210	DNA helicase
FQU85_RS03020	COG0006	proline dipeptidase activity
FQU85_RS03035	COG2339	peptidase activity
FQU85_RS03070	COG0442	prolyl-tRNA aminoacylation
FQU85_RS03085	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FQU85_RS03095	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FQU85_RS03110	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FQU85_RS03160	COG0557	exoribonuclease II activity
FQU85_RS03180	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FQU85_RS03185	COG0460	homoserine dehydrogenase
FQU85_RS03195	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FQU85_RS03210	COG0049	tRNA binding
FQU85_RS03225	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FQU85_RS03230	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FQU85_RS03235	COG0085	RNA polymerase activity
FQU85_RS03240	COG0085	RNA polymerase activity
FQU85_RS03275	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FQU85_RS03285	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FQU85_RS03300	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FQU85_RS03335	COG1278	Cold shock
FQU85_RS03340	COG0534	Mate efflux family protein
FQU85_RS03345	COG1024	Enoyl-CoA hydratase
FQU85_RS03375	COG1132	(ABC) transporter
FQU85_RS03380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FQU85_RS03395	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FQU85_RS03405	COG3842	ATPase activity
FQU85_RS03415	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FQU85_RS03490	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FQU85_RS03525	COG0351	phosphomethylpyrimidine kinase
FQU85_RS03525	COG0352	thiamine-phosphate diphosphorylase activity
FQU85_RS03535	COG3118	belongs to the thioredoxin family
FQU85_RS03545	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
FQU85_RS03555	COG0140	phosphoribosyl-ATP diphosphatase activity
FQU85_RS03560	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FQU85_RS03580	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FQU85_RS03590	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FQU85_RS03595	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
FQU85_RS03595	COG0778	Nitroreductase
FQU85_RS03600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FQU85_RS03605	COG0714	Associated with various cellular activities
FQU85_RS03615	COG1305	Transglutaminase-like
FQU85_RS03665	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FQU85_RS03670	COG2855	membrane
FQU85_RS03685	COG3794	PFAM blue (type 1) copper domain protein
FQU85_RS03700	COG0534	Mate efflux family protein
FQU85_RS03710	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FQU85_RS03715	COG1132	(ABC) transporter
FQU85_RS03720	COG1120	ATPase activity
FQU85_RS03725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FQU85_RS03800	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FQU85_RS03820	COG0456	acetyltransferase
FQU85_RS03820	COG0454	-acetyltransferase
FQU85_RS03880	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FQU85_RS03885	COG0723	plastoquinol--plastocyanin reductase activity
FQU85_RS03895	COG3794	PFAM blue (type 1) copper domain protein
FQU85_RS03935	COG0167	dihydroorotate dehydrogenase activity
FQU85_RS03940	COG0072	phenylalanine-tRNA ligase activity
FQU85_RS03940	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FQU85_RS03970	COG0534	Mate efflux family protein
FQU85_RS03975	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FQU85_RS04005	COG0071	Belongs to the small heat shock protein (HSP20) family
FQU85_RS04010	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FQU85_RS04020	COG0495	leucyl-tRNA aminoacylation
FQU85_RS04030	COG0459	protein refolding
FQU85_RS04065	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FQU85_RS04075	COG1234	tRNA 3'-trailer cleavage
FQU85_RS04095	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FQU85_RS04100	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FQU85_RS04115	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FQU85_RS04115	COG0116	Belongs to the methyltransferase superfamily
FQU85_RS04130	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FQU85_RS04140	COG0402	S-adenosylhomocysteine deaminase activity
FQU85_RS04150	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FQU85_RS04180	COG0688	phosphatidylethanolamine metabolic process
FQU85_RS04195	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FQU85_RS04210	COG0805	protein transport
FQU85_RS04220	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FQU85_RS04235	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FQU85_RS04245	COG2827	Endonuclease containing a URI domain
FQU85_RS04250	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FQU85_RS04270	COG2255	four-way junction helicase activity
FQU85_RS04275	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FQU85_RS04280	COG0435	Glutathione S-transferase
FQU85_RS04285	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FQU85_RS04295	COG1078	dGTPase activity
FQU85_RS04300	COG0519	Catalyzes the synthesis of GMP from XMP
FQU85_RS04300	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FQU85_RS04345	COG0702	epimerase
FQU85_RS04360	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FQU85_RS04375	COG0822	iron-sulfur transferase activity
FQU85_RS04385	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FQU85_RS04415	COG2897	thiosulfate sulfurtransferase activity
FQU85_RS04420	COG2897	thiosulfate sulfurtransferase activity
FQU85_RS04435	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FQU85_RS04440	COG2226	methyltransferase
FQU85_RS04450	COG0556	nucleotide-excision repair
FQU85_RS04470	COG0589	response to stress
FQU85_RS04480	COG0330	HflC and HflK could
FQU85_RS04485	COG0322	excinuclease ABC activity
FQU85_RS04505	COG1131	(ABC) transporter
FQU85_RS04520	COG0039	L-malate dehydrogenase activity
FQU85_RS04540	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FQU85_RS04565	COG0656	L-ascorbic acid biosynthetic process
FQU85_RS04575	COG0527	aspartate kinase activity
FQU85_RS04595	COG1160	GTP binding
FQU85_RS04615	COG0534	Mate efflux family protein
FQU85_RS04630	COG0589	response to stress
FQU85_RS04635	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FQU85_RS04670	COG0444	Belongs to the ABC transporter superfamily
FQU85_RS04675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FQU85_RS04680	COG0601	transmembrane transport
FQU85_RS04695	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FQU85_RS04705	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FQU85_RS04710	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FQU85_RS04715	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FQU85_RS04720	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FQU85_RS04725	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FQU85_RS04730	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FQU85_RS04735	COG0189	ligase activity
FQU85_RS04745	COG0165	Argininosuccinate lyase
FQU85_RS04750	COG0137	argininosuccinate synthase activity
FQU85_RS04810	COG0563	adenylate kinase activity
FQU85_RS04850	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FQU85_RS04860	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FQU85_RS04885	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FQU85_RS04890	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FQU85_RS04910	COG2873	o-acetylhomoserine
FQU85_RS04915	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FQU85_RS04920	COG2873	o-acetylhomoserine
FQU85_RS04925	COG0560	Phosphoserine phosphatase
FQU85_RS04950	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FQU85_RS04980	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FQU85_RS04985	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FQU85_RS05025	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FQU85_RS05025	COG1648	precorrin-2 dehydrogenase activity
FQU85_RS05030	COG0181	hydroxymethylbilane synthase activity
FQU85_RS05035	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FQU85_RS05040	COG0004	ammonium transporteR
FQU85_RS05045	COG0113	porphobilinogen synthase activity
FQU85_RS05055	COG0247	lactate metabolic process
FQU85_RS05055	COG2181	nitrate reductase activity
FQU85_RS05065	COG1122	ATPase activity
FQU85_RS05085	COG0009	L-threonylcarbamoyladenylate synthase
FQU85_RS05100	COG1253	flavin adenine dinucleotide binding
FQU85_RS05130	COG1966	Carbon starvation protein
FQU85_RS05135	COG0003	Pfam Anion-transporting ATPase
FQU85_RS05150	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FQU85_RS05160	COG0823	Involved in the tonB-independent uptake of proteins
FQU85_RS05160	COG1506	peptidase
FQU85_RS05160	COG4946	Tricorn protease homolog
FQU85_RS05165	COG3842	ATPase activity
FQU85_RS05175	COG1176	ABC-type spermidine putrescine transport system, permease component I
FQU85_RS05180	COG1177	transmembrane transport
FQU85_RS05185	COG1739	Uncharacterized protein family UPF0029
FQU85_RS05195	COG0131	Imidazoleglycerol-phosphate dehydratase
FQU85_RS05200	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FQU85_RS05225	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FQU85_RS05235	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FQU85_RS05255	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FQU85_RS05260	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FQU85_RS05295	COG0489	protein tyrosine kinase activity
FQU85_RS05320	COG1372	Participates in initiation and elongation during chromosome replication
FQU85_RS05320	COG0305	Participates in initiation and elongation during chromosome replication
FQU85_RS05335	COG0471	metal ion transport
FQU85_RS05335	COG3273	potassium ion transport
FQU85_RS05350	COG0517	IMP dehydrogenase activity
FQU85_RS05350	COG1994	Peptidase M50
FQU85_RS05385	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FQU85_RS05385	COG0662	Cupin 2, conserved barrel domain protein
FQU85_RS05440	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FQU85_RS05465	COG2226	methyltransferase
FQU85_RS05475	COG1269	ATP hydrolysis coupled proton transport
FQU85_RS05500	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
FQU85_RS05510	COG1394	ATPase activity, coupled to movement of substances
FQU85_RS05520	COG1012	belongs to the aldehyde dehydrogenase family
FQU85_RS05535	COG0018	arginyl-trna synthetase
FQU85_RS05555	COG0731	radical SAM domain protein
FQU85_RS05565	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FQU85_RS05580	COG0506	proline dehydrogenase activity
FQU85_RS05590	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FQU85_RS05600	COG2252	PERMEase
FQU85_RS05625	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FQU85_RS05630	COG3608	succinylglutamate desuccinylase aspartoacylase
FQU85_RS05640	COG0372	Belongs to the citrate synthase family
FQU85_RS05650	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FQU85_RS05660	COG0251	oxidation-reduction process
FQU85_RS05685	COG0459	protein refolding
FQU85_RS05690	COG1522	sequence-specific DNA binding
FQU85_RS05710	COG1867	N(2),N(2)-dimethylguanosine tRNA methyltransferase
FQU85_RS05735	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FQU85_RS05740	COG1573	uracil-dna glycosylase
FQU85_RS05755	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FQU85_RS05780	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FQU85_RS05790	COG0589	response to stress
FQU85_RS05795	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FQU85_RS05805	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FQU85_RS05815	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FQU85_RS05825	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FQU85_RS05845	COG0183	Belongs to the thiolase family
FQU85_RS05855	COG0464	growth
FQU85_RS05885	COG0539	negative regulation of cytoplasmic translation
FQU85_RS05910	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FQU85_RS05920	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FQU85_RS05935	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FQU85_RS05940	COG4208	sulfate ABC transporter
FQU85_RS05945	COG0725	ABC transporter, periplasmic molybdate-binding protein
FQU85_RS05955	COG2814	Major facilitator Superfamily
FQU85_RS05970	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
FQU85_RS05995	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FQU85_RS06005	COG5658	integral membrane protein
FQU85_RS06025	COG0667	Aldo Keto reductase
FQU85_RS06035	COG1695	Transcriptional regulator
FQU85_RS06040	COG0750	zinc metalloprotease
FQU85_RS06050	COG0528	UMP kinase activity
FQU85_RS06055	COG0314	molybdopterin synthase activity
FQU85_RS06095	COG0482	sulfurtransferase activity
FQU85_RS06100	COG0124	histidyl-tRNA synthetase
FQU85_RS06115	COG1164	Oligoendopeptidase f
FQU85_RS06120	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FQU85_RS06145	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FQU85_RS06170	COG0166	Belongs to the GPI family
FQU85_RS06195	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FQU85_RS06205	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FQU85_RS06235	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
FQU85_RS06240	COG4191	Histidine kinase
FQU85_RS06245	COG2202	Pas domain
FQU85_RS06245	COG1366	Belongs to the anti-sigma-factor antagonist family
FQU85_RS06250	COG2205	protein histidine kinase activity
FQU85_RS06255	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FQU85_RS06315	COG1131	(ABC) transporter
FQU85_RS06415	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FQU85_RS06420	COG0702	epimerase
FQU85_RS06430	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FQU85_RS06450	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FQU85_RS06460	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FQU85_RS06470	COG0788	formyltetrahydrofolate deformylase activity
FQU85_RS06485	COG0047	phosphoribosylformylglycinamidine synthase activity
FQU85_RS06520	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FQU85_RS06540	COG1522	sequence-specific DNA binding
FQU85_RS06590	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FQU85_RS06610	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FQU85_RS06630	COG4535	Mg2 and Co2 transporter CorC
FQU85_RS06640	COG3634	alkyl hydroperoxide reductase activity
FQU85_RS06655	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FQU85_RS06660	COG0135	phosphoribosylanthranilate isomerase activity
FQU85_RS06665	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FQU85_RS06670	COG0512	Glutamine amidotransferase of anthranilate synthase
FQU85_RS06670	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FQU85_RS06690	COG1028	Short-chain dehydrogenase reductase Sdr
FQU85_RS06700	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
FQU85_RS06725	COG0589	response to stress
FQU85_RS06740	COG0129	dihydroxy-acid dehydratase activity
FQU85_RS06780	COG3361	conserved protein (COG2071)
FQU85_RS06785	COG1233	COG1233 Phytoene dehydrogenase and related
FQU85_RS06840	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FQU85_RS06875	COG1132	(ABC) transporter
FQU85_RS06900	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FQU85_RS06910	COG0303	'Molybdopterin
FQU85_RS06925	COG2154	pterin-4-alpha-carbinolamine dehydratase
FQU85_RS06930	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FQU85_RS06935	COG1648	precorrin-2 dehydrogenase activity
FQU85_RS06935	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FQU85_RS06950	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FQU85_RS06955	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FQU85_RS06970	COG0477	Major facilitator Superfamily
FQU85_RS07000	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
FQU85_RS07030	COG0318	PFAM AMP-dependent synthetase and ligase
FQU85_RS07060	COG1131	(ABC) transporter
FQU85_RS07070	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FQU85_RS07080	COG0505	Belongs to the CarA family
FQU85_RS07090	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FQU85_RS07100	COG1028	Short-chain dehydrogenase reductase Sdr
FQU85_RS07115	COG0521	Mo-molybdopterin cofactor biosynthetic process
FQU85_RS07140	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FQU85_RS07140	COG0519	Catalyzes the synthesis of GMP from XMP
FQU85_RS07145	COG0504	CTP synthase activity
FQU85_RS07195	COG4948	Mandelate Racemase Muconate Lactonizing
FQU85_RS07225	COG0252	asparaginase activity
FQU85_RS07250	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FQU85_RS07260	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
FQU85_RS07280	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FQU85_RS07285	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FQU85_RS07295	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FQU85_RS07320	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FQU85_RS07325	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FQU85_RS07330	COG1446	asparaginase
FQU85_RS07375	COG4555	ABC transporter
FQU85_RS07400	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FQU85_RS07430	COG0284	orotidine-5'-phosphate decarboxylase activity
FQU85_RS07440	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FQU85_RS07455	COG3252	Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT
FQU85_RS07475	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FQU85_RS07480	COG0088	Forms part of the polypeptide exit tunnel
FQU85_RS07490	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FQU85_RS07495	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FQU85_RS07505	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FQU85_RS07510	COG0255	Belongs to the universal ribosomal protein uL29 family
FQU85_RS07525	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FQU85_RS07540	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FQU85_RS07550	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FQU85_RS07555	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FQU85_RS07560	COG0322	excinuclease ABC activity
FQU85_RS07575	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FQU85_RS07585	COG0200	Binds to the 23S rRNA
FQU85_RS07595	COG0569	domain protein
FQU85_RS07615	COG0531	amino acid
FQU85_RS07620	COG0531	amino acid
FQU85_RS07625	COG0563	adenylate kinase activity
FQU85_RS07635	COG1102	Psort location Cytoplasmic, score
FQU85_RS07640	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FQU85_RS07720	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FQU85_RS07725	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FQU85_RS07745	COG4191	Histidine kinase
FQU85_RS07750	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FQU85_RS07775	COG1968	undecaprenyl-diphosphatase activity
FQU85_RS07865	COG0438	transferase activity, transferring glycosyl groups
FQU85_RS07890	COG1088	dTDP-glucose 4,6-dehydratase activity
FQU85_RS07895	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FQU85_RS07900	COG1051	belongs to the nudix hydrolase family
FQU85_RS07920	COG1201	RNA secondary structure unwinding
FQU85_RS07925	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FQU85_RS07955	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FQU85_RS07985	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FQU85_RS07995	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FQU85_RS08080	COG0572	uridine kinase
FQU85_RS08090	COG0126	phosphoglycerate kinase activity
FQU85_RS08115	COG0656	L-ascorbic acid biosynthetic process
FQU85_RS08135	COG0110	maltose O-acetyltransferase activity
FQU85_RS08160	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FQU85_RS08170	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FQU85_RS08210	COG0626	cystathionine gamma-synthase activity
FQU85_RS08230	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FQU85_RS08240	COG2264	protein methyltransferase activity
FQU85_RS08255	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FQU85_RS08270	COG0105	UTP biosynthetic process
FQU85_RS08295	COG1444	tRNA N-acetyltransferase activity
FQU85_RS08305	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FQU85_RS08310	COG2267	carboxylic ester hydrolase activity
FQU85_RS08315	COG0142	geranyltranstransferase activity
FQU85_RS08320	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FQU85_RS08330	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FQU85_RS08345	COG0052	Belongs to the universal ribosomal protein uS2 family
FQU85_RS08365	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FQU85_RS08375	COG0200	Binds to the 23S rRNA
FQU85_RS08390	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FQU85_RS08395	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FQU85_RS08400	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FQU85_RS08410	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FQU85_RS08415	COG0489	protein tyrosine kinase activity
FQU85_RS08435	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FQU85_RS08435	COG0674	pyruvate-flavodoxin oxidoreductase activity
FQU85_RS08440	COG1013	pyruvate-flavodoxin oxidoreductase activity
FQU85_RS08445	COG1522	sequence-specific DNA binding
FQU85_RS08450	COG0436	Aminotransferase
FQU85_RS08460	COG0492	ferredoxin-NADP+ reductase activity
FQU85_RS08470	COG1250	3-hydroxyacyl-CoA dehydrogenase
FQU85_RS08490	COG0596	Alpha beta hydrolase
FQU85_RS08495	COG1960	acyl-CoA dehydrogenase activity
FQU85_RS08500	COG0318	PFAM AMP-dependent synthetase and ligase
FQU85_RS08515	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FQU85_RS08530	COG0183	Belongs to the thiolase family
FQU85_RS08545	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FQU85_RS08550	COG1454	alcohol dehydrogenase
FQU85_RS08570	COG0657	acetylesterase activity
FQU85_RS08580	COG0531	amino acid
FQU85_RS08585	COG3844	kynureninase activity
FQU85_RS08620	COG0318	PFAM AMP-dependent synthetase and ligase
FQU85_RS08625	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FQU85_RS08670	COG0559	Belongs to the binding-protein-dependent transport system permease family
FQU85_RS08695	COG1028	Short-chain dehydrogenase reductase Sdr
FQU85_RS08700	COG0318	PFAM AMP-dependent synthetase and ligase
FQU85_RS08720	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FQU85_RS08735	COG2030	dehydratase
FQU85_RS08740	COG1024	Enoyl-CoA hydratase
FQU85_RS08745	COG0277	FAD linked oxidase domain protein
FQU85_RS08750	COG0028	Belongs to the TPP enzyme family
FQU85_RS08770	COG1028	Short-chain dehydrogenase reductase Sdr
FQU85_RS08775	COG0667	Aldo Keto reductase
FQU85_RS08780	COG1294	oxidase, subunit
FQU85_RS08785	COG1271	oxidase subunit
FQU85_RS08810	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FQU85_RS08820	COG2022	thiamine diphosphate biosynthetic process
FQU85_RS08830	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FQU85_RS08845	COG1253	flavin adenine dinucleotide binding
FQU85_RS08850	COG0857	belongs to the CobB CobQ family
FQU85_RS08870	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FQU85_RS08875	COG1902	pentaerythritol trinitrate reductase activity
FQU85_RS08880	COG0490	domain, Protein
FQU85_RS08885	COG0475	glutathione-regulated potassium exporter activity
FQU85_RS08920	COG0662	Cupin 2, conserved barrel domain protein
FQU85_RS08930	COG0463	Glycosyl transferase, family 2
FQU85_RS08980	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FQU85_RS08995	COG0438	transferase activity, transferring glycosyl groups
FQU85_RS09000	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FQU85_RS09015	COG1215	transferase activity, transferring glycosyl groups
FQU85_RS09025	COG0297	glycogen (starch) synthase activity
FQU85_RS09035	COG0438	transferase activity, transferring glycosyl groups
FQU85_RS09060	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FQU85_RS09075	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FQU85_RS09095	COG1994	Peptidase M50
FQU85_RS09105	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FQU85_RS09135	COG1793	dna ligase
FQU85_RS09145	COG0647	UMP catabolic process
FQU85_RS09150	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FQU85_RS09180	COG0187	DNA topoisomerase II activity
FQU85_RS09185	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FQU85_RS09195	COG1252	NADH dehydrogenase
FQU85_RS09205	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FQU85_RS09210	COG0010	Belongs to the arginase family
FQU85_RS09215	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FQU85_RS09220	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FQU85_RS09225	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FQU85_RS09230	COG2409	Drug exporters of the RND superfamily
FQU85_RS09240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FQU85_RS09255	COG0704	Plays a role in the regulation of phosphate uptake
FQU85_RS09260	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FQU85_RS09265	COG0581	inorganic phosphate transmembrane transporter activity
FQU85_RS09270	COG0573	inorganic phosphate transmembrane transporter activity
FQU85_RS09275	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FQU85_RS09300	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FQU85_RS09305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FQU85_RS09350	COG2226	methyltransferase
FQU85_RS09370	COG0271	Belongs to the BolA IbaG family
FQU85_RS09380	COG0114	fumarate hydratase activity
FQU85_RS09400	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FQU85_RS09405	COG0633	Ferredoxin
FQU85_RS09405	COG3217	Mosc domain protein beta barrel domain protein
FQU85_RS09415	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FQU85_RS09420	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FQU85_RS09430	COG4166	transmembrane transport
FQU85_RS09440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FQU85_RS09445	COG0444	Belongs to the ABC transporter superfamily
FQU85_RS09450	COG4608	Belongs to the ABC transporter superfamily
FQU85_RS09475	COG0501	Belongs to the peptidase M48B family
FQU85_RS09480	COG0667	Aldo Keto reductase
FQU85_RS09485	COG0596	Alpha beta hydrolase
FQU85_RS09495	COG0346	lactoylglutathione lyase activity
FQU85_RS09500	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FQU85_RS09510	COG0697	spore germination
FQU85_RS09520	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FQU85_RS09540	COG1028	Short-chain dehydrogenase reductase Sdr
FQU85_RS09540	COG0604	alcohol dehydrogenase
FQU85_RS09540	COG3321	synthase
FQU85_RS09545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FQU85_RS09550	COG1335	isochorismatase
FQU85_RS09565	COG0318	PFAM AMP-dependent synthetase and ligase
FQU85_RS09570	COG1024	Enoyl-CoA hydratase
FQU85_RS09580	COG0415	Belongs to the DNA photolyase family
FQU85_RS09590	COG1047	Peptidyl-prolyl cis-trans
FQU85_RS09615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FQU85_RS09630	COG1116	anion transmembrane transporter activity
FQU85_RS09635	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FQU85_RS09640	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FQU85_RS09695	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FQU85_RS09745	COG1397	ADP-ribosylglycohydrolase
FQU85_RS09910	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FQU85_RS09985	COG2409	Drug exporters of the RND superfamily
FQU85_RS10050	COG3842	ATPase activity
FQU85_RS10070	COG2264	protein methyltransferase activity
FQU85_RS10115	COG1169	isochorismate synthase
FQU85_RS10120	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FQU85_RS10130	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FQU85_RS10140	COG1575	Belongs to the MenA family. Type 1 subfamily
FQU85_RS10150	COG0318	PFAM AMP-dependent synthetase and ligase
FQU85_RS10175	COG0154	amidase activity
FQU85_RS10180	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FQU85_RS10195	COG1028	Short-chain dehydrogenase reductase Sdr
FQU85_RS10205	COG0587	DNA-directed DNA polymerase activity
FQU85_RS10225	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FQU85_RS10235	COG0107	imidazoleglycerol-phosphate synthase activity
FQU85_RS10265	COG4974	Belongs to the 'phage' integrase family
FQU85_RS10310	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FQU85_RS10330	COG0081	regulation of translation
FQU85_RS10350	COG0598	Magnesium transport protein CorA
FQU85_RS10360	COG0215	cysteine-tRNA ligase activity
FQU85_RS10395	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FQU85_RS10410	COG1250	3-hydroxyacyl-CoA dehydrogenase
FQU85_RS10430	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FQU85_RS10480	COG0517	IMP dehydrogenase activity
FQU85_RS10480	COG0516	GMP reductase activity
FQU85_RS10565	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FQU85_RS10565	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FQU85_RS10580	COG2226	methyltransferase
FQU85_RS10605	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FQU85_RS10610	COG1744	ABC transporter substrate-binding protein PnrA-like
FQU85_RS10615	COG3845	ABC transporter
FQU85_RS10620	COG4603	Belongs to the binding-protein-dependent transport system permease family
FQU85_RS10625	COG1079	Belongs to the binding-protein-dependent transport system permease family
FQU85_RS10640	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FQU85_RS10675	COG0704	Plays a role in the regulation of phosphate uptake
FQU85_RS10680	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FQU85_RS10685	COG0573	inorganic phosphate transmembrane transporter activity
FQU85_RS10690	COG0573	inorganic phosphate transmembrane transporter activity
FQU85_RS10695	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FQU85_RS10700	COG0704	Plays a role in the regulation of phosphate uptake
FQU85_RS10745	COG1213	nucleotidyl transferase
FQU85_RS10745	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FQU85_RS10755	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FQU85_RS10770	COG0179	Fumarylacetoacetate (FAA) hydrolase
FQU85_RS10775	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FQU85_RS10805	COG1024	Enoyl-CoA hydratase
FQU85_RS10820	COG2030	dehydratase
FQU85_RS10825	COG2301	Belongs to the HpcH HpaI aldolase family
FQU85_RS10830	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FQU85_RS10835	COG0667	Aldo Keto reductase
FQU85_RS10840	COG0405	Gamma-glutamyltransferase
FQU85_RS10845	COG1960	acyl-CoA dehydrogenase activity
FQU85_RS10905	COG1546	Belongs to the CinA family
FQU85_RS10905	COG1058	Belongs to the CinA family
FQU85_RS10955	COG1757	Na H antiporter
FQU85_RS10980	COG0437	4 iron, 4 sulfur cluster binding
FQU85_RS11015	COG2414	aldehyde ferredoxin oxidoreductase
FQU85_RS11035	COG2130	NADP-dependent
FQU85_RS11045	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FQU85_RS11050	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FQU85_RS11065	COG1228	amidohydrolase
FQU85_RS11080	COG1063	alcohol dehydrogenase
FQU85_RS11085	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FQU85_RS11100	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FQU85_RS11110	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FQU85_RS11125	COG0506	proline dehydrogenase activity
FQU85_RS11135	COG0559	Belongs to the binding-protein-dependent transport system permease family
FQU85_RS11155	COG0697	spore germination
FQU85_RS11185	COG1305	Transglutaminase-like
FQU85_RS11205	COG0714	Associated with various cellular activities
FQU85_RS11210	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FQU85_RS11220	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FQU85_RS11225	COG0656	L-ascorbic acid biosynthetic process
FQU85_RS11240	COG1013	pyruvate-flavodoxin oxidoreductase activity
FQU85_RS11245	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FQU85_RS11245	COG0674	pyruvate-flavodoxin oxidoreductase activity
FQU85_RS11260	COG0346	lactoylglutathione lyase activity
FQU85_RS11265	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FQU85_RS11265	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FQU85_RS11270	COG0701	Predicted permease
FQU85_RS11280	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FQU85_RS11295	COG2031	fatty acid transporter
FQU85_RS11300	COG0484	heat shock protein binding
FQU85_RS11305	COG0443	Heat shock 70 kDa protein
FQU85_RS11310	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FQU85_RS11340	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FQU85_RS11340	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
FQU85_RS11350	COG1116	anion transmembrane transporter activity
FQU85_RS11355	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FQU85_RS11365	COG0436	Aminotransferase
FQU85_RS11375	COG1546	Belongs to the CinA family
FQU85_RS11375	COG1058	Belongs to the CinA family
FQU85_RS11385	COG1253	flavin adenine dinucleotide binding
FQU85_RS11410	COG0559	Belongs to the binding-protein-dependent transport system permease family
FQU85_RS11425	COG0410	ABC transporter
FQU85_RS11435	COG2746	aminoglycoside 3-N-acetyltransferase activity
FQU85_RS11440	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FQU85_RS11455	COG0419	ATPase involved in DNA repair
FQU85_RS11480	COG4221	oxidoreductase activity
FQU85_RS11485	COG0396	ATPase activity
FQU85_RS11490	COG0719	Fe-S assembly protein
FQU85_RS11495	COG0719	Fe-S assembly protein
FQU85_RS11535	COG2119	membrane
FQU85_RS11545	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FQU85_RS11565	COG1098	S1 RNA binding domain
FQU85_RS11610	COG4608	Belongs to the ABC transporter superfamily
FQU85_RS11615	COG0444	Belongs to the ABC transporter superfamily
FQU85_RS11620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FQU85_RS11625	COG0601	transmembrane transport
FQU85_RS11640	COG2111	Na H antiporter
FQU85_RS11640	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FQU85_RS11645	COG2111	Na H antiporter
FQU85_RS11650	COG1006	Multisubunit Na H antiporter MnhC subunit
FQU85_RS11655	COG0651	ATP synthesis coupled electron transport
FQU85_RS11660	COG1863	multisubunit Na H antiporter MnhE subunit
FQU85_RS11665	COG2212	antiporter activity
FQU85_RS11670	COG1320	monovalent cation:proton antiporter activity
FQU85_RS11680	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FQU85_RS11700	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FQU85_RS11705	COG2234	aminopeptidase activity
FQU85_RS11725	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FQU85_RS11730	COG1012	belongs to the aldehyde dehydrogenase family
FQU85_RS11740	COG1252	NADH dehydrogenase
FQU85_RS11750	COG0438	transferase activity, transferring glycosyl groups
FQU85_RS11770	COG0668	transmembrane transport
FQU85_RS11785	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FQU85_RS11795	COG0109	protoheme IX farnesyltransferase activity
FQU85_RS11800	COG1278	Cold shock
FQU85_RS11810	COG1522	sequence-specific DNA binding
FQU85_RS11815	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FQU85_RS11820	COG3002	Belongs to the UPF0753 family
FQU85_RS11825	COG0077	Prephenate dehydratase
FQU85_RS11825	COG1605	Chorismate mutase
FQU85_RS11840	COG1129	ABC transporter
FQU85_RS11855	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FQU85_RS11860	COG1201	RNA secondary structure unwinding
FQU85_RS11885	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FQU85_RS11885	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FQU85_RS11950	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FQU85_RS11960	COG1254	Belongs to the acylphosphatase family
FQU85_RS11965	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FQU85_RS11965	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FQU85_RS11970	COG0315	cyclic pyranopterin monophosphate synthase activity
FQU85_RS11980	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FQU85_RS12020	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FQU85_RS12050	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
FQU85_RS12055	COG0540	Belongs to the ATCase OTCase family
FQU85_RS12080	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
FQU85_RS12095	COG0456	acetyltransferase
FQU85_RS12125	COG1053	succinate dehydrogenase
FQU85_RS12130	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FQU85_RS12150	COG0189	ligase activity
FQU85_RS12160	COG1250	3-hydroxyacyl-CoA dehydrogenase
FQU85_RS12185	COG2988	succinylglutamate desuccinylase activity
FQU85_RS12195	COG0483	inositol monophosphate 1-phosphatase activity
FQU85_RS12200	COG1522	sequence-specific DNA binding
FQU85_RS12215	COG2193	ferroxidase activity
FQU85_RS12220	COG0151	Belongs to the GarS family
FQU85_RS12225	COG1331	Highly conserved protein containing a thioredoxin domain
FQU85_RS12235	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FQU85_RS12245	COG0301	tRNA thio-modification
FQU85_RS12260	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FQU85_RS12275	COG1960	acyl-CoA dehydrogenase activity
FQU85_RS12295	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FQU85_RS12315	COG1363	Peptidase, m42
FQU85_RS12350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FQU85_RS12370	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FQU85_RS12385	COG0539	negative regulation of cytoplasmic translation
FQU85_RS12395	COG1435	thymidine kinase activity
FQU85_RS12400	COG1194	a g-specific adenine glycosylase
FQU85_RS12415	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FQU85_RS12420	COG1285	pathogenesis
FQU85_RS12445	COG0471	metal ion transport
FQU85_RS12460	COG0657	acetylesterase activity
FQU85_RS12465	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FQU85_RS12470	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FQU85_RS12495	COG0442	prolyl-tRNA aminoacylation
FQU85_RS12505	COG0668	transmembrane transport
FQU85_RS12515	COG0737	Belongs to the 5'-nucleotidase family
FQU85_RS12540	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FQU85_RS12555	COG0316	Belongs to the HesB IscA family
FQU85_RS12560	COG3360	Dodecin
FQU85_RS12580	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FQU85_RS12630	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FQU85_RS12635	COG1078	dGTPase activity
FQU85_RS12640	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FQU85_RS12645	COG0589	response to stress
FQU85_RS12650	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FQU85_RS12650	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FQU85_RS12655	COG4770	biotin carboxylase activity
FQU85_RS12665	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FQU85_RS12670	COG0733	neurotransmitter:sodium symporter activity
FQU85_RS12680	COG0045	succinate-CoA ligase (ADP-forming) activity
FQU85_RS12685	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FQU85_RS12740	COG2096	Adenosyltransferase
FQU85_RS12750	COG0017	Asparaginyl-tRNA synthetase
FQU85_RS12770	COG0864	Transcriptional regulator
FQU85_RS12775	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FQU85_RS12780	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FQU85_RS12785	COG0509	glycine decarboxylation via glycine cleavage system
FQU85_RS12845	COG2255	four-way junction helicase activity
FQU85_RS12850	COG1757	Na H antiporter
FQU85_RS12860	COG1126	abc transporter atp-binding protein
FQU85_RS12865	COG0765	amino acid transport
FQU85_RS12870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FQU85_RS12880	COG0280	phosphate acetyltransferase
FQU85_RS12880	COG0281	malic enzyme
FQU85_RS12895	COG0798	PFAM Bile acid sodium symporter
FQU85_RS12900	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FQU85_RS12915	COG0601	transmembrane transport
FQU85_RS12920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FQU85_RS12925	COG0444	Belongs to the ABC transporter superfamily
FQU85_RS12930	COG4608	Belongs to the ABC transporter superfamily
FQU85_RS12935	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
FQU85_RS12940	COG0697	spore germination
FQU85_RS13010	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FQU85_RS13065	COG0175	sulfate reduction
FQU85_RS13125	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FQU85_RS13130	COG0302	gtp cyclohydrolase
FQU85_RS13135	COG0602	queuosine metabolic process