locus-tag	class	description
AAT16_RS00065	COG1388	LysM domain
AAT16_RS00070	COG2132	Multicopper oxidase
AAT16_RS00080	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AAT16_RS00080	COG0519	Catalyzes the synthesis of GMP from XMP
AAT16_RS00085	COG0517	IMP dehydrogenase activity
AAT16_RS00085	COG0516	GMP reductase activity
AAT16_RS00110	COG1012	belongs to the aldehyde dehydrogenase family
AAT16_RS00115	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AAT16_RS00120	COG0629	single-stranded DNA binding
AAT16_RS00130	COG0012	GTP binding
AAT16_RS00135	COG4481	Protein conserved in bacteria
AAT16_RS00140	COG0668	transmembrane transport
AAT16_RS00145	COG1475	DNA binding
AAT16_RS00150	COG1475	DNA binding
AAT16_RS00155	COG0357	Ribosomal RNA small subunit methyltransferase G
AAT16_RS00160	COG0445	tRNA wobble uridine modification
AAT16_RS00165	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AAT16_RS00175	COG0594	ribonuclease P activity
AAT16_RS00180	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AAT16_RS00185	COG0592	DNA-directed DNA polymerase activity
AAT16_RS00195	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AAT16_RS00200	COG0187	DNA topoisomerase II activity
AAT16_RS00215	COG2986	histidine ammonia-lyase
AAT16_RS00220	COG0583	DNA-binding transcription factor activity
AAT16_RS00225	COG3314	Sporulation integral membrane protein YlbJ
AAT16_RS00235	COG1228	amidohydrolase
AAT16_RS00240	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AAT16_RS00255	COG0359	binds to the 23S rRNA
AAT16_RS00260	COG0305	Participates in initiation and elongation during chromosome replication
AAT16_RS00265	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AAT16_RS00270	COG0529	Catalyzes the synthesis of activated sulfate
AAT16_RS00275	COG2046	Belongs to the sulfate adenylyltransferase family
AAT16_RS00280	COG0730	response to heat
AAT16_RS00300	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AAT16_RS00305	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AAT16_RS00310	COG0175	sulfate reduction
AAT16_RS00325	COG0745	RESPONSE REGULATOR receiver
AAT16_RS00330	COG5002	protein histidine kinase activity
AAT16_RS00345	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AAT16_RS00355	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AAT16_RS00365	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AAT16_RS00370	COG1028	Short-chain dehydrogenase reductase Sdr
AAT16_RS00380	COG2186	Transcriptional regulator
AAT16_RS00385	COG2807	transmembrane transport
AAT16_RS00390	COG0069	glutamate synthase activity
AAT16_RS00410	COG1388	LysM domain
AAT16_RS00415	COG1388	LysM domain
AAT16_RS00430	COG2268	Band 7 protein
AAT16_RS00440	COG1902	pentaerythritol trinitrate reductase activity
AAT16_RS00445	COG0667	Aldo Keto reductase
AAT16_RS00450	COG0564	pseudouridine synthase activity
AAT16_RS00455	COG2154	pterin-4-alpha-carbinolamine dehydratase
AAT16_RS00465	COG0463	Glycosyl transferase, family 2
AAT16_RS00465	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AAT16_RS00480	COG2427	Protein of unknown function (DUF1641)
AAT16_RS00485	COG3383	formate dehydrogenase (NAD+) activity
AAT16_RS00495	COG3942	CHAP domain
AAT16_RS00500	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AAT16_RS00505	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
AAT16_RS00510	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AAT16_RS00525	COG1607	acyl-coa hydrolase
AAT16_RS00530	COG0583	DNA-binding transcription factor activity
AAT16_RS00540	COG1120	ATPase activity
AAT16_RS00545	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AAT16_RS00585	COG2329	Antibiotic biosynthesis monooxygenase
AAT16_RS00595	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AAT16_RS00600	COG1279	arginine transmembrane transporter activity
AAT16_RS00605	COG0725	ABC transporter, periplasmic molybdate-binding protein
AAT16_RS00610	COG4149	molybdate abc transporter
AAT16_RS00630	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AAT16_RS00670	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AAT16_RS00670	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AAT16_RS00680	COG0659	secondary active sulfate transmembrane transporter activity
AAT16_RS00695	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AAT16_RS00700	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AAT16_RS00725	COG1461	Dihydroxyacetone kinase
AAT16_RS00730	COG2376	Dihydroxyacetone kinase
AAT16_RS00735	COG1012	belongs to the aldehyde dehydrogenase family
AAT16_RS00745	COG0402	S-adenosylhomocysteine deaminase activity
AAT16_RS00750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AAT16_RS00755	COG1435	thymidine kinase activity
AAT16_RS00765	COG0745	RESPONSE REGULATOR receiver
AAT16_RS00770	COG5002	protein histidine kinase activity
AAT16_RS00770	COG3850	Histidine kinase
AAT16_RS00790	COG1464	Belongs to the NlpA lipoprotein family
AAT16_RS00800	COG1115	amino acid carrier protein
AAT16_RS00805	COG1827	regulation of RNA biosynthetic process
AAT16_RS00810	COG1104	cysteine desulfurase activity
AAT16_RS00815	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AAT16_RS00820	COG0157	Belongs to the NadC ModD family
AAT16_RS00825	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AAT16_RS00830	COG2814	Major facilitator Superfamily
AAT16_RS00835	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AAT16_RS00840	COG0583	DNA-binding transcription factor activity
AAT16_RS00865	COG0579	oxidoreductase
AAT16_RS00870	COG1136	(ABC) transporter
AAT16_RS00875	COG0577	efflux transmembrane transporter activity
AAT16_RS00885	COG1695	Transcriptional regulator
AAT16_RS00895	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AAT16_RS00900	COG1528	Iron-storage protein
AAT16_RS00910	COG1126	abc transporter atp-binding protein
AAT16_RS00915	COG0765	amino acid transport
AAT16_RS00920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AAT16_RS00925	COG0431	NADPH-dependent FMN reductase
AAT16_RS00930	COG0626	cystathionine gamma-synthase activity
AAT16_RS00935	COG0626	cystathionine gamma-synthase activity
AAT16_RS00945	COG0628	permease
AAT16_RS00950	COG1028	Short-chain dehydrogenase reductase Sdr
AAT16_RS00960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AAT16_RS00975	COG0287	Prephenate dehydrogenase
AAT16_RS00980	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AAT16_RS00990	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AAT16_RS01000	COG1647	Serine aminopeptidase, S33
AAT16_RS01005	COG3949	Membrane
AAT16_RS01015	COG2076	Multidrug Resistance protein
AAT16_RS01020	COG2076	Multidrug Resistance protein
AAT16_RS01040	COG2056	Na+-H+ antiporter family
AAT16_RS01045	COG0534	Mate efflux family protein
AAT16_RS01050	COG1028	Short-chain dehydrogenase reductase Sdr
AAT16_RS01055	COG1012	belongs to the aldehyde dehydrogenase family
AAT16_RS01070	COG0431	NADPH-dependent FMN reductase
AAT16_RS01080	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AAT16_RS01085	COG2223	nitrite transmembrane transporter activity
AAT16_RS01090	COG0243	molybdopterin cofactor binding
AAT16_RS01095	COG0733	neurotransmitter:sodium symporter activity
AAT16_RS01100	COG0789	Transcriptional regulator
AAT16_RS01120	COG0714	Associated with various cellular activities
AAT16_RS01125	COG0446	pyridine nucleotide-disulphide oxidoreductase
AAT16_RS01130	COG1283	sodium-dependent phosphate transmembrane transporter activity
AAT16_RS01140	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AAT16_RS01145	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AAT16_RS01180	COG1609	Transcriptional regulator
AAT16_RS01190	COG0673	inositol 2-dehydrogenase activity
AAT16_RS01195	COG0673	inositol 2-dehydrogenase activity
AAT16_RS01205	COG3842	ATPase activity
AAT16_RS01220	COG2348	transferase activity, transferring amino-acyl groups
AAT16_RS01225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AAT16_RS01230	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AAT16_RS01235	COG1140	nitrate reductase beta subunit
AAT16_RS01245	COG2181	nitrate reductase activity
AAT16_RS01265	COG2814	Major facilitator Superfamily
AAT16_RS01275	COG2364	Membrane
AAT16_RS01280	COG2252	PERMEase
AAT16_RS01290	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AAT16_RS01295	COG0088	Forms part of the polypeptide exit tunnel
AAT16_RS01300	COG0089	rRNA binding
AAT16_RS01305	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AAT16_RS01310	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AAT16_RS01315	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AAT16_RS01325	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AAT16_RS01330	COG0255	Belongs to the universal ribosomal protein uL29 family
AAT16_RS01335	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AAT16_RS01340	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AAT16_RS01350	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AAT16_RS01355	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AAT16_RS01360	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AAT16_RS01365	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AAT16_RS01370	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AAT16_RS01375	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AAT16_RS01380	COG1841	ribosomal large subunit assembly
AAT16_RS01390	COG0201	protein transport
AAT16_RS01405	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AAT16_RS01410	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AAT16_RS01420	COG0202	RNA polymerase activity
AAT16_RS01425	COG0203	ribosomal protein L17
AAT16_RS01430	COG1122	ATPase activity
AAT16_RS01435	COG1122	ATPase activity
AAT16_RS01440	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AAT16_RS01445	COG0101	tRNA pseudouridine synthase activity
AAT16_RS01450	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AAT16_RS01455	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AAT16_RS01460	COG0028	Belongs to the TPP enzyme family
AAT16_RS01465	COG2828	Protein conserved in bacteria
AAT16_RS01470	COG0583	DNA-binding transcription factor activity
AAT16_RS01475	COG2851	Citrate transporter
AAT16_RS01495	COG2318	DinB family
AAT16_RS01500	COG0596	Alpha beta hydrolase
AAT16_RS01505	COG1388	LysM domain
AAT16_RS01520	COG4377	Putative membrane peptidase family (DUF2324)
AAT16_RS01535	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AAT16_RS01540	COG1140	nitrate reductase beta subunit
AAT16_RS01550	COG2181	nitrate reductase activity
AAT16_RS01560	COG4585	Histidine kinase
AAT16_RS01575	COG2223	nitrite transmembrane transporter activity
AAT16_RS01580	COG4608	Belongs to the ABC transporter superfamily
AAT16_RS01585	COG0444	Belongs to the ABC transporter superfamily
AAT16_RS01590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AAT16_RS01595	COG0601	transmembrane transport
AAT16_RS01600	COG4166	transmembrane transport
AAT16_RS01615	COG2814	Major facilitator Superfamily
AAT16_RS01620	COG2814	Major facilitator Superfamily
AAT16_RS01640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AAT16_RS01670	COG0604	alcohol dehydrogenase
AAT16_RS01690	COG0561	phosphatase activity
AAT16_RS01705	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AAT16_RS01710	COG0783	Belongs to the Dps family
AAT16_RS01720	COG1846	Transcriptional regulator
AAT16_RS01725	COG0655	NAD(P)H dehydrogenase (quinone) activity
AAT16_RS01735	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AAT16_RS01740	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AAT16_RS01745	COG1121	(ABC) transporter
AAT16_RS01750	COG0803	Belongs to the bacterial solute-binding protein 9 family
AAT16_RS01755	COG1011	Hydrolase
AAT16_RS01760	COG1640	4-alpha-glucanotransferase
AAT16_RS01765	COG0058	SHG alpha-glucan phosphorylase activity
AAT16_RS01775	COG0300	oxidoreductase activity
AAT16_RS01780	COG3844	kynureninase activity
AAT16_RS01785	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AAT16_RS01800	COG2358	TRAP transporter, solute receptor (TAXI family
AAT16_RS01820	COG0438	transferase activity, transferring glycosyl groups
AAT16_RS01825	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AAT16_RS01835	COG1272	protein, Hemolysin III
AAT16_RS01840	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AAT16_RS01845	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AAT16_RS01860	COG0668	transmembrane transport
AAT16_RS01865	COG0489	protein tyrosine kinase activity
AAT16_RS01920	COG0010	Belongs to the arginase family
AAT16_RS01945	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AAT16_RS01955	COG1428	Deoxynucleoside kinase
AAT16_RS01980	COG0542	response to heat
AAT16_RS01985	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AAT16_RS01990	COG1012	belongs to the aldehyde dehydrogenase family
AAT16_RS02005	COG0006	proline dipeptidase activity
AAT16_RS02025	COG0667	Aldo Keto reductase
AAT16_RS02040	COG2818	Glycosylase
AAT16_RS02065	COG0730	response to heat
AAT16_RS02070	COG0586	Pfam SNARE associated Golgi protein
AAT16_RS02080	COG3239	Fatty acid desaturase
AAT16_RS02085	COG4585	Histidine kinase
AAT16_RS02090	COG2197	response regulator
AAT16_RS02095	COG1131	(ABC) transporter
AAT16_RS02100	COG1511	domain protein
AAT16_RS02100	COG0842	Transport permease protein
AAT16_RS02110	COG1063	alcohol dehydrogenase
AAT16_RS02120	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AAT16_RS02125	COG1253	flavin adenine dinucleotide binding
AAT16_RS02140	COG1486	melibiose metabolic process
AAT16_RS02145	COG0561	phosphatase activity
AAT16_RS02150	COG1988	membrane-bound metal-dependent
AAT16_RS02165	COG4895	conserved protein (DUF2196)
AAT16_RS02170	COG0477	Major facilitator Superfamily
AAT16_RS02180	COG1131	(ABC) transporter
AAT16_RS02185	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AAT16_RS02190	COG0385	Bile acid
AAT16_RS02195	COG4122	O-methyltransferase activity
AAT16_RS02205	COG0604	alcohol dehydrogenase
AAT16_RS02215	COG0405	Gamma-glutamyltransferase
AAT16_RS02225	COG0720	synthase
AAT16_RS02240	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AAT16_RS02280	COG3942	CHAP domain
AAT16_RS02280	COG1388	LysM domain
AAT16_RS02290	COG0217	transcriptional regulatory protein
AAT16_RS02295	COG1028	Short-chain dehydrogenase reductase Sdr
AAT16_RS02300	COG1725	Transcriptional regulator
AAT16_RS02305	COG1131	(ABC) transporter
AAT16_RS02320	COG1028	Short-chain dehydrogenase reductase Sdr
AAT16_RS02325	COG0583	DNA-binding transcription factor activity
AAT16_RS02335	COG2839	Protein conserved in bacteria
AAT16_RS02345	COG0747	negative chemotaxis
AAT16_RS02375	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
AAT16_RS02380	COG5002	protein histidine kinase activity
AAT16_RS02385	COG0745	RESPONSE REGULATOR receiver
AAT16_RS02390	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AAT16_RS02395	COG0521	Mo-molybdopterin cofactor biosynthetic process
AAT16_RS02400	COG0315	cyclic pyranopterin monophosphate synthase activity
AAT16_RS02405	COG0303	'Molybdopterin
AAT16_RS02425	COG0746	molybdenum cofactor guanylyltransferase activity
AAT16_RS02430	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AAT16_RS02435	COG4988	ABC transporter
AAT16_RS02440	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AAT16_RS02445	COG1307	EDD domain protein, DegV family
AAT16_RS02450	COG1253	flavin adenine dinucleotide binding
AAT16_RS02470	COG2814	Major facilitator Superfamily
AAT16_RS02475	COG0512	Glutamine amidotransferase of anthranilate synthase
AAT16_RS02475	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AAT16_RS02500	COG0514	ATP-dependent DNA helicase (RecQ)
AAT16_RS02510	COG1780	Probably involved in ribonucleotide reductase function
AAT16_RS02515	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AAT16_RS02520	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AAT16_RS02525	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AAT16_RS02525	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AAT16_RS02535	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AAT16_RS02535	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AAT16_RS02540	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AAT16_RS02555	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AAT16_RS02560	COG4605	iron ion homeostasis
AAT16_RS02565	COG4604	ABC transporter, ATP-binding protein
AAT16_RS02570	COG4607	ABC-type enterochelin transport system periplasmic component
AAT16_RS02575	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AAT16_RS02590	COG3118	belongs to the thioredoxin family
AAT16_RS02600	COG1316	TRANSCRIPTIONal
AAT16_RS02605	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AAT16_RS02610	COG1739	Uncharacterized protein family UPF0029
AAT16_RS02615	COG1307	EDD domain protein, DegV family
AAT16_RS02620	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AAT16_RS02625	COG1040	competence protein
AAT16_RS02630	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AAT16_RS02635	COG0653	protein targeting
AAT16_RS02640	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AAT16_RS02650	COG3942	CHAP domain
AAT16_RS02660	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AAT16_RS02685	COG3595	metallopeptidase activity
AAT16_RS02690	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AAT16_RS02700	COG0110	maltose O-acetyltransferase activity
AAT16_RS02715	COG1660	Displays ATPase and GTPase activities
AAT16_RS02720	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AAT16_RS02725	COG1481	regulation of sporulation
AAT16_RS02735	COG0740	serine-type endopeptidase activity
AAT16_RS02745	COG2966	Psort location CytoplasmicMembrane, score
AAT16_RS02760	COG2390	Transcriptional regulator
AAT16_RS02765	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AAT16_RS02770	COG0126	phosphoglycerate kinase activity
AAT16_RS02780	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AAT16_RS02785	COG0148	phosphopyruvate hydratase activity
AAT16_RS02790	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AAT16_RS02795	COG1647	Serine aminopeptidase, S33
AAT16_RS02800	COG0557	exoribonuclease II activity
AAT16_RS02805	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AAT16_RS02810	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AAT16_RS02815	COG3189	MarR family transcriptional regulator
AAT16_RS02825	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AAT16_RS02830	COG1393	Belongs to the ArsC family
AAT16_RS02835	COG0509	glycine decarboxylation via glycine cleavage system
AAT16_RS02840	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AAT16_RS02850	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AAT16_RS02855	COG2011	ABC-type metal ion transport system permease component
AAT16_RS02860	COG1464	Belongs to the NlpA lipoprotein family
AAT16_RS02930	COG1716	ATPase activity
AAT16_RS02940	COG2815	serine threonine protein kinase
AAT16_RS02940	COG0515	serine threonine protein kinase
AAT16_RS02955	COG0396	ATPase activity
AAT16_RS02960	COG0719	Fe-S assembly protein
AAT16_RS02970	COG0822	iron-sulfur transferase activity
AAT16_RS02975	COG0719	Fe-S assembly protein
AAT16_RS02980	COG0109	protoheme IX farnesyltransferase activity
AAT16_RS02995	COG1876	peptidase activity
AAT16_RS03005	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AAT16_RS03020	COG0697	spore germination
AAT16_RS03035	COG0390	transport system, permease component
AAT16_RS03040	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AAT16_RS03045	COG1801	Protein of unknown function DUF72
AAT16_RS03050	COG0730	response to heat
AAT16_RS03055	COG0737	Belongs to the 5'-nucleotidase family
AAT16_RS03060	COG1757	Na H antiporter
AAT16_RS03065	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AAT16_RS03070	COG4470	Protein conserved in bacteria
AAT16_RS03080	COG2445	Protein of unknown function DUF86
AAT16_RS03090	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AAT16_RS03100	COG4837	Protein of unknown function (DUF1462)
AAT16_RS03105	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AAT16_RS03110	COG1252	NADH dehydrogenase
AAT16_RS03115	COG4844	belongs to the
AAT16_RS03120	COG0316	Belongs to the HesB IscA family
AAT16_RS03125	COG1252	NADH dehydrogenase
AAT16_RS03135	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AAT16_RS03140	COG2050	protein possibly involved in aromatic compounds catabolism
AAT16_RS03145	COG1320	monovalent cation:proton antiporter activity
AAT16_RS03150	COG2212	antiporter activity
AAT16_RS03155	COG1863	multisubunit Na H antiporter MnhE subunit
AAT16_RS03170	COG2111	Na H antiporter
AAT16_RS03180	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AAT16_RS03195	COG1098	S1 RNA binding domain
AAT16_RS03200	COG1012	belongs to the aldehyde dehydrogenase family
AAT16_RS03205	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AAT16_RS03220	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AAT16_RS03230	COG0135	phosphoribosylanthranilate isomerase activity
AAT16_RS03245	COG0166	Belongs to the GPI family
AAT16_RS03265	COG1074	ATP-dependent DNA helicase activity
AAT16_RS03285	COG0366	Alpha amylase catalytic
AAT16_RS03285	COG1874	Beta-galactosidase
AAT16_RS03295	COG0446	pyridine nucleotide-disulphide oxidoreductase
AAT16_RS03300	COG1307	EDD domain protein, DegV family
AAT16_RS03305	COG0561	phosphatase activity
AAT16_RS03310	COG2151	metal-sulfur cluster biosynthetic enzyme
AAT16_RS03315	COG1968	undecaprenyl-diphosphatase activity
AAT16_RS03320	COG0542	response to heat
AAT16_RS03325	COG1115	amino acid carrier protein
AAT16_RS03330	COG1126	abc transporter atp-binding protein
AAT16_RS03335	COG0765	amino acid transport
AAT16_RS03340	COG0765	amino acid transport
AAT16_RS03345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AAT16_RS03350	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AAT16_RS03355	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AAT16_RS03360	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AAT16_RS03365	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
AAT16_RS03370	COG2070	2-Nitropropane dioxygenase
AAT16_RS03385	COG4608	Belongs to the ABC transporter superfamily
AAT16_RS03390	COG0601	transmembrane transport
AAT16_RS03395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AAT16_RS03410	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AAT16_RS03415	COG0180	Tryptophanyl-tRNA synthetase
AAT16_RS03420	COG1393	Belongs to the ArsC family
AAT16_RS03425	COG4862	establishment of competence for transformation
AAT16_RS03435	COG1164	Oligoendopeptidase f
AAT16_RS03440	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AAT16_RS03445	COG2346	COG2346, Truncated hemoglobins
AAT16_RS03460	COG2357	RelA SpoT domain protein
AAT16_RS03470	COG2239	Acts as a magnesium transporter
AAT16_RS03475	COG0569	domain protein
AAT16_RS03475	COG0475	glutathione-regulated potassium exporter activity
AAT16_RS03495	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AAT16_RS03500	COG2382	esterase
AAT16_RS03505	COG1115	amino acid carrier protein
AAT16_RS03510	COG0628	permease
AAT16_RS03520	COG1131	(ABC) transporter
AAT16_RS03525	COG1309	transcriptional regulator
AAT16_RS03550	COG0805	protein transport
AAT16_RS03555	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AAT16_RS03565	COG0805	protein transport
AAT16_RS03585	COG2814	Major facilitator Superfamily
AAT16_RS03605	COG0861	Integral membrane protein TerC family
AAT16_RS03610	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AAT16_RS03615	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AAT16_RS03635	COG4873	Protein conserved in bacteria
AAT16_RS03690	COG0297	glycogen (starch) synthase activity
AAT16_RS03710	COG1134	teichoic acid transport
AAT16_RS03735	COG1316	TRANSCRIPTIONal
AAT16_RS03755	COG1134	teichoic acid transport
AAT16_RS03785	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AAT16_RS03795	COG1442	glycosyl transferase family 8
AAT16_RS03795	COG1216	Glycosyl transferase, family 2
AAT16_RS03815	COG0463	Glycosyl transferase, family 2
AAT16_RS03855	COG1181	Belongs to the D-alanine--D-alanine ligase family
AAT16_RS03855	COG2918	glutathione biosynthetic process
AAT16_RS03865	COG2153	protein acetylation
AAT16_RS03890	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AAT16_RS03915	COG1234	tRNA 3'-trailer cleavage
AAT16_RS03935	COG2814	Major facilitator Superfamily
AAT16_RS03950	COG1757	Na H antiporter
AAT16_RS03955	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AAT16_RS03960	COG2204	response regulator
AAT16_RS03970	COG1134	teichoic acid transport
AAT16_RS03975	COG1682	transport, permease protein
AAT16_RS03980	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AAT16_RS03985	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AAT16_RS04010	COG3949	Membrane
AAT16_RS04020	COG3944	biosynthesis protein
AAT16_RS04030	COG4464	protein tyrosine phosphatase activity
AAT16_RS04045	COG1086	Polysaccharide biosynthesis protein
AAT16_RS04085	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AAT16_RS04115	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AAT16_RS04160	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AAT16_RS04180	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AAT16_RS04185	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AAT16_RS04195	COG3775	system Galactitol-specific IIC component
AAT16_RS04215	COG0561	phosphatase activity
AAT16_RS04220	COG0406	alpha-ribazole phosphatase activity
AAT16_RS04225	COG1070	Carbohydrate kinase
AAT16_RS04240	COG2188	Transcriptional regulator
AAT16_RS04245	COG1486	melibiose metabolic process
AAT16_RS04250	COG3394	polysaccharide catabolic process
AAT16_RS04255	COG1263	PTS System
AAT16_RS04255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AAT16_RS04260	COG1349	DNA-binding transcription factor activity
AAT16_RS04265	COG1028	Short-chain dehydrogenase reductase Sdr
AAT16_RS04270	COG1063	alcohol dehydrogenase
AAT16_RS04275	COG2814	Major facilitator Superfamily
AAT16_RS04280	COG2376	Dihydroxyacetone kinase
AAT16_RS04290	COG0698	ribose 5-phosphate isomerase
AAT16_RS04295	COG1494	fructose-1,6-bisphosphatase
AAT16_RS04310	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AAT16_RS04315	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AAT16_RS04325	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AAT16_RS04335	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
AAT16_RS04340	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AAT16_RS04340	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AAT16_RS04375	COG2161	toxin-antitoxin pair type II binding
AAT16_RS04400	COG0006	proline dipeptidase activity
AAT16_RS04410	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
AAT16_RS04420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AAT16_RS04420	COG2190	(PTS) system
AAT16_RS04420	COG1263	PTS System
AAT16_RS04425	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AAT16_RS04440	COG1609	Transcriptional regulator
AAT16_RS04445	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AAT16_RS04450	COG1869	D-ribose catabolic process
AAT16_RS04455	COG1129	ABC transporter
AAT16_RS04460	COG1172	Belongs to the binding-protein-dependent transport system permease family
AAT16_RS04465	COG1879	ABC-type sugar transport system periplasmic component
AAT16_RS04475	COG2326	polyphosphate kinase activity
AAT16_RS04490	COG1511	domain protein
AAT16_RS04495	COG4297	protein containing double-stranded beta helix domain
AAT16_RS04510	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AAT16_RS04515	COG2068	MobA-Related Protein
AAT16_RS04545	COG1024	Enoyl-CoA hydratase
AAT16_RS04555	COG0318	PFAM AMP-dependent synthetase and ligase
AAT16_RS04560	COG2207	Transcriptional regulator
AAT16_RS04570	COG1280	lysine exporter protein (LysE YggA)
AAT16_RS04580	COG1757	Na H antiporter
AAT16_RS04595	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
AAT16_RS04600	COG3626	phosphonate metabolism
AAT16_RS04605	COG3627	carbon phosphorus lyase activity
AAT16_RS04610	COG4107	phosphonate C-P lyase system protein PhnK
AAT16_RS04615	COG3454	Phosphonate metabolism
AAT16_RS04620	COG4778	phosphonate C-P lyase system protein PhnL
AAT16_RS04625	COG0613	PHP domain protein
AAT16_RS04635	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AAT16_RS04640	COG3639	organic phosphonate transmembrane transporter activity
AAT16_RS04645	COG3639	organic phosphonate transmembrane transporter activity
AAT16_RS04650	COG2391	methyltransferase activity
AAT16_RS04660	COG3443	Belongs to the bacterial solute-binding protein 9 family
AAT16_RS04700	COG0346	lactoylglutathione lyase activity
AAT16_RS04720	COG0346	lactoylglutathione lyase activity
AAT16_RS04735	COG4122	O-methyltransferase activity
AAT16_RS04740	COG1012	belongs to the aldehyde dehydrogenase family
AAT16_RS04755	COG1802	Transcriptional regulator
AAT16_RS04760	COG0471	metal ion transport
AAT16_RS04770	COG1929	Belongs to the glycerate kinase type-1 family
AAT16_RS04825	COG1473	amidohydrolase
AAT16_RS04835	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AAT16_RS04840	COG0667	Aldo Keto reductase
AAT16_RS04845	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AAT16_RS04855	COG0386	Belongs to the glutathione peroxidase family
AAT16_RS04865	COG3273	potassium ion transport
AAT16_RS04865	COG0471	metal ion transport
AAT16_RS04870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AAT16_RS04875	COG0431	NADPH-dependent FMN reductase
AAT16_RS04895	COG1288	antiporter activity
AAT16_RS04900	COG0471	metal ion transport
AAT16_RS04950	COG0693	protein deglycase activity
AAT16_RS04960	COG1959	2 iron, 2 sulfur cluster binding
AAT16_RS04965	COG1017	nitric oxide dioxygenase activity
AAT16_RS04965	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AAT16_RS04975	COG5002	protein histidine kinase activity
AAT16_RS04975	COG3850	Histidine kinase
AAT16_RS05000	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AAT16_RS05005	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AAT16_RS05015	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AAT16_RS05030	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AAT16_RS05035	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AAT16_RS05040	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AAT16_RS05050	COG0138	bifunctional purine biosynthesis protein purh
AAT16_RS05070	COG0010	Belongs to the arginase family
AAT16_RS05075	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AAT16_RS05085	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AAT16_RS05090	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AAT16_RS05100	COG1271	oxidase subunit
AAT16_RS05105	COG1294	oxidase, subunit
AAT16_RS05110	COG0569	domain protein
AAT16_RS05115	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AAT16_RS05150	COG0508	dehydrogenase complex catalyzes the overall conversion of
AAT16_RS05175	COG0385	Bile acid
AAT16_RS05180	COG0129	dihydroxy-acid dehydratase activity
AAT16_RS05185	COG0028	Belongs to the TPP enzyme family
AAT16_RS05190	COG0440	acetolactate synthase activity
AAT16_RS05195	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AAT16_RS05200	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AAT16_RS05205	COG0473	3-isopropylmalate dehydrogenase activity
AAT16_RS05210	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AAT16_RS05215	COG0066	3-isopropylmalate dehydratase activity
AAT16_RS05220	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AAT16_RS05225	COG4493	Belongs to the UPF0637 family
AAT16_RS05230	COG0483	inositol monophosphate 1-phosphatase activity
AAT16_RS05250	COG1217	gtp-binding protein TYPA
AAT16_RS05260	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AAT16_RS05265	COG4838	Belongs to the UPF0358 family
AAT16_RS05270	COG0772	Belongs to the SEDS family
AAT16_RS05285	COG1612	heme a metabolic process
AAT16_RS05290	COG0109	protoheme IX farnesyltransferase activity
AAT16_RS05310	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AAT16_RS05315	COG3336	cytochrome c oxidase
AAT16_RS05330	COG3679	Belongs to the UPF0342 family
AAT16_RS05335	COG0584	glycerophosphoryl diester phosphodiesterase
AAT16_RS05350	COG0742	ribosomal rna small subunit methyltransferase
AAT16_RS05355	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AAT16_RS05360	COG1323	Belongs to the UPF0348 family
AAT16_RS05375	COG0454	-acetyltransferase
AAT16_RS05380	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
AAT16_RS05385	COG2001	Belongs to the MraZ family
AAT16_RS05390	COG0275	rRNA processing
AAT16_RS05400	COG0768	penicillin binding
AAT16_RS05410	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AAT16_RS05415	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AAT16_RS05425	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AAT16_RS05430	COG1496	oxidoreductase activity
AAT16_RS05435	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AAT16_RS05440	COG1799	cell septum assembly
AAT16_RS05450	COG2302	S4 RNA-binding domain
AAT16_RS05455	COG3599	regulation of cell shape
AAT16_RS05460	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AAT16_RS05465	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AAT16_RS05470	COG0564	pseudouridine synthase activity
AAT16_RS05475	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AAT16_RS05480	COG2233	PERMEase
AAT16_RS05485	COG0540	Belongs to the ATCase OTCase family
AAT16_RS05495	COG0505	Belongs to the CarA family
AAT16_RS05500	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AAT16_RS05505	COG0543	2 iron, 2 sulfur cluster binding
AAT16_RS05510	COG0167	dihydroorotate dehydrogenase activity
AAT16_RS05515	COG0284	orotidine-5'-phosphate decarboxylase activity
AAT16_RS05525	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AAT16_RS05530	COG1523	belongs to the glycosyl hydrolase 13 family
AAT16_RS05535	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AAT16_RS05540	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AAT16_RS05550	COG0297	glycogen (starch) synthase activity
AAT16_RS05555	COG1293	RNA-binding protein homologous to eukaryotic snRNP
AAT16_RS05565	COG1758	RNA polymerase activity
AAT16_RS05570	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AAT16_RS05575	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AAT16_RS05580	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AAT16_RS05585	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AAT16_RS05585	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AAT16_RS05590	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AAT16_RS05595	COG0631	protein serine/threonine phosphatase activity
AAT16_RS05605	COG2124	cytochrome p450
AAT16_RS05610	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AAT16_RS05615	COG1162	GTPase activity
AAT16_RS05620	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AAT16_RS05625	COG1564	THIamine pyrophosphokinase
AAT16_RS05635	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AAT16_RS05640	COG1302	Protein conserved in bacteria
AAT16_RS05645	COG1461	Dihydroxyacetone kinase
AAT16_RS05650	COG1760	l-serine dehydratase
AAT16_RS05655	COG1760	l-serine dehydratase
AAT16_RS05660	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AAT16_RS05665	COG3764	Sortase (surface protein transpeptidase)
AAT16_RS05690	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AAT16_RS05695	COG0571	ribonuclease III activity
AAT16_RS05700	COG1196	nuclear chromosome segregation
AAT16_RS05705	COG0552	protein localization to endoplasmic reticulum
AAT16_RS05710	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
AAT16_RS05715	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AAT16_RS05720	COG0228	four-way junction DNA binding
AAT16_RS05725	COG1837	Belongs to the UPF0109 family
AAT16_RS05730	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AAT16_RS05735	COG0336	Belongs to the RNA methyltransferase TrmD family
AAT16_RS05740	COG0335	large ribosomal subunit rRNA binding
AAT16_RS05750	COG4485	Bacterial membrane protein, YfhO
AAT16_RS05760	COG0463	Glycosyl transferase, family 2
AAT16_RS05765	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AAT16_RS05770	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AAT16_RS05775	COG0045	succinate-CoA ligase (ADP-forming) activity
AAT16_RS05780	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AAT16_RS05785	COG0758	DNA mediated transformation
AAT16_RS05790	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AAT16_RS05795	COG4974	Belongs to the 'phage' integrase family
AAT16_RS05800	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AAT16_RS05805	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AAT16_RS05810	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AAT16_RS05815	COG0052	Belongs to the universal ribosomal protein uS2 family
AAT16_RS05820	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AAT16_RS05825	COG0528	UMP kinase activity
AAT16_RS05830	COG0233	cytoplasmic translational termination
AAT16_RS05840	COG4589	Belongs to the CDS family
AAT16_RS05845	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AAT16_RS05855	COG0442	prolyl-tRNA aminoacylation
AAT16_RS05865	COG0779	Required for maturation of 30S ribosomal subunits
AAT16_RS05870	COG0195	Participates in both transcription termination and antitermination
AAT16_RS05875	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AAT16_RS05885	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AAT16_RS05890	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AAT16_RS05895	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AAT16_RS05900	COG0196	riboflavin kinase activity
AAT16_RS05905	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AAT16_RS05910	COG1185	polyribonucleotide nucleotidyltransferase activity
AAT16_RS05920	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AAT16_RS05925	COG1674	ftsk spoiiie
AAT16_RS05935	COG0612	Peptidase, M16
AAT16_RS05955	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AAT16_RS05960	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AAT16_RS05965	COG1418	mRNA catabolic process
AAT16_RS05975	COG1692	metallophosphoesterase
AAT16_RS05980	COG0674	pyruvate-flavodoxin oxidoreductase activity
AAT16_RS05980	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AAT16_RS05985	COG1013	pyruvate-flavodoxin oxidoreductase activity
AAT16_RS05990	COG1132	(ABC) transporter
AAT16_RS05995	COG1132	(ABC) transporter
AAT16_RS06005	COG1122	ATPase activity
AAT16_RS06015	COG4550	Control of competence regulator ComK, YlbF/YmcA
AAT16_RS06025	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AAT16_RS06040	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AAT16_RS06045	COG1923	regulation of RNA biosynthetic process
AAT16_RS06050	COG0386	Belongs to the glutathione peroxidase family
AAT16_RS06055	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AAT16_RS06060	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
AAT16_RS06075	COG3655	Transcriptional regulator
AAT16_RS06100	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AAT16_RS06105	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AAT16_RS06115	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AAT16_RS06135	COG3763	UPF0154 protein
AAT16_RS06145	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AAT16_RS06155	COG0352	thiamine-phosphate diphosphorylase activity
AAT16_RS06160	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AAT16_RS06170	COG2022	thiamine diphosphate biosynthetic process
AAT16_RS06175	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AAT16_RS06180	COG1132	(ABC) transporter
AAT16_RS06185	COG1132	(ABC) transporter
AAT16_RS06190	COG0785	Cytochrome C biogenesis protein
AAT16_RS06195	COG4846	Membrane protein involved in cytochrome C biogenesis
AAT16_RS06215	COG0420	3'-5' exonuclease activity
AAT16_RS06225	COG1999	signal sequence binding
AAT16_RS06230	COG1957	nucleoside hydrolase
AAT16_RS06245	COG4224	UPF0291 protein
AAT16_RS06250	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AAT16_RS06270	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AAT16_RS06275	COG2003	Belongs to the UPF0758 family
AAT16_RS06295	COG0702	epimerase
AAT16_RS06300	COG1132	(ABC) transporter
AAT16_RS06305	COG1132	(ABC) transporter
AAT16_RS06310	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AAT16_RS06315	COG2011	ABC-type metal ion transport system permease component
AAT16_RS06325	COG0436	Aminotransferase
AAT16_RS06345	COG2868	ribosomal protein
AAT16_RS06350	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AAT16_RS06355	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AAT16_RS06360	COG0632	four-way junction helicase activity
AAT16_RS06365	COG2255	four-way junction helicase activity
AAT16_RS06370	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AAT16_RS06375	COG0343	queuine tRNA-ribosyltransferase activity
AAT16_RS06380	COG1862	Preprotein translocase
AAT16_RS06385	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AAT16_RS06385	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AAT16_RS06390	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AAT16_RS06390	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AAT16_RS06395	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AAT16_RS06410	COG0860	N-Acetylmuramoyl-L-alanine amidase
AAT16_RS06415	COG0124	histidyl-tRNA synthetase
AAT16_RS06420	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AAT16_RS06425	COG0402	S-adenosylhomocysteine deaminase activity
AAT16_RS06450	COG0745	RESPONSE REGULATOR receiver
AAT16_RS06455	COG0642	Histidine kinase
AAT16_RS06460	COG1619	proteins homologs of microcin C7 resistance protein MccF
AAT16_RS06480	COG0456	acetyltransferase
AAT16_RS06485	COG1073	alpha beta
AAT16_RS06485	COG2226	methyltransferase
AAT16_RS06495	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AAT16_RS06500	COG2130	NADP-dependent
AAT16_RS06510	COG1174	glycine betaine transport
AAT16_RS06525	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AAT16_RS06530	COG1733	regulation of RNA biosynthetic process
AAT16_RS06535	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AAT16_RS06540	COG1959	2 iron, 2 sulfur cluster binding
AAT16_RS06545	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AAT16_RS06550	COG0527	aspartate kinase activity
AAT16_RS06555	COG0460	homoserine dehydrogenase
AAT16_RS06560	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AAT16_RS06565	COG0083	homoserine kinase activity
AAT16_RS06570	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AAT16_RS06575	COG1104	cysteine desulfurase activity
AAT16_RS06580	COG0482	sulfurtransferase activity
AAT16_RS06590	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AAT16_RS06595	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AAT16_RS06600	COG4472	Bacterial protein of unknown function (DUF965)
AAT16_RS06605	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AAT16_RS06610	COG3906	Belongs to the UPF0473 family
AAT16_RS06615	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AAT16_RS06620	COG4122	O-methyltransferase activity
AAT16_RS06625	COG0572	uridine kinase
AAT16_RS06630	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AAT16_RS06635	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AAT16_RS06640	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AAT16_RS06645	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AAT16_RS06650	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AAT16_RS06655	COG1534	Rna-binding protein
AAT16_RS06660	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AAT16_RS06665	COG1713	HD superfamily hydrolase involved in NAD metabolism
AAT16_RS06670	COG0799	negative regulation of ribosome biogenesis
AAT16_RS06675	COG4106	trans-aconitate 2-methyltransferase activity
AAT16_RS06680	COG1555	photosystem II stabilization
AAT16_RS06685	COG2131	deaminase
AAT16_RS06690	COG0658	competence protein
AAT16_RS06690	COG2333	competence protein COMEC
AAT16_RS06700	COG0268	Binds directly to 16S ribosomal RNA
AAT16_RS06705	COG0481	GTPase activity
AAT16_RS06710	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AAT16_RS06715	COG1420	regulation of RNA biosynthetic process
AAT16_RS06725	COG0443	Heat shock 70 kDa protein
AAT16_RS06730	COG0484	heat shock protein binding
AAT16_RS06735	COG2264	protein methyltransferase activity
AAT16_RS06740	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AAT16_RS06745	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AAT16_RS06750	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AAT16_RS06755	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AAT16_RS06760	COG1030	water channel activity
AAT16_RS06765	COG4864	UPF0365 protein
AAT16_RS06775	COG1349	DNA-binding transcription factor activity
AAT16_RS06780	COG1105	Belongs to the carbohydrate kinase PfkB family
AAT16_RS06785	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AAT16_RS06785	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AAT16_RS06785	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AAT16_RS06795	COG1473	amidohydrolase
AAT16_RS06805	COG2388	GCN5-related N-acetyl-transferase
AAT16_RS06855	COG1028	Short-chain dehydrogenase reductase Sdr
AAT16_RS06865	COG1702	phosphate starvation-inducible protein PhoH
AAT16_RS06870	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AAT16_RS06875	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AAT16_RS06880	COG0295	cytidine deaminase activity
AAT16_RS06890	COG1381	Involved in DNA repair and RecF pathway recombination
AAT16_RS06895	COG0423	glycine-tRNA ligase activity
AAT16_RS06900	COG0517	IMP dehydrogenase activity
AAT16_RS06905	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AAT16_RS06920	COG2010	Cytochrome c
AAT16_RS06925	COG2384	SAM-dependent methyltransferase
AAT16_RS06935	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AAT16_RS06940	COG0513	Belongs to the DEAD box helicase family
AAT16_RS06945	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AAT16_RS06950	COG1121	(ABC) transporter
AAT16_RS06955	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AAT16_RS06965	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AAT16_RS06975	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AAT16_RS06985	COG0768	penicillin binding
AAT16_RS06995	COG0573	inorganic phosphate transmembrane transporter activity
AAT16_RS07000	COG0581	inorganic phosphate transmembrane transporter activity
AAT16_RS07005	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AAT16_RS07010	COG0704	Plays a role in the regulation of phosphate uptake
AAT16_RS07015	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AAT16_RS07020	COG0705	Rhomboid family
AAT16_RS07020	COG0457	Tetratricopeptide repeat
AAT16_RS07030	COG1940	carbohydrate kinase activity
AAT16_RS07035	COG1028	Short-chain dehydrogenase reductase Sdr
AAT16_RS07040	COG0137	argininosuccinate synthase activity
AAT16_RS07045	COG0165	Argininosuccinate lyase
AAT16_RS07055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AAT16_RS07065	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AAT16_RS07075	COG4537	Required for transformation and DNA binding
AAT16_RS07095	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AAT16_RS07105	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AAT16_RS07110	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AAT16_RS07115	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AAT16_RS07120	COG0095	Lipoate-protein ligase
AAT16_RS07130	COG3872	metal-dependent enzyme
AAT16_RS07145	COG0006	proline dipeptidase activity
AAT16_RS07150	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AAT16_RS07155	COG0511	ligase activity, forming carbon-carbon bonds
AAT16_RS07160	COG0439	Biotin carboxylase
AAT16_RS07170	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AAT16_RS07175	COG1570	exodeoxyribonuclease VII activity
AAT16_RS07190	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AAT16_RS07195	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AAT16_RS07200	COG1438	arginine binding
AAT16_RS07205	COG0497	DNA recombination
AAT16_RS07215	COG0280	phosphate acetyltransferase
AAT16_RS07225	COG3426	butyrate kinase activity
AAT16_RS07230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AAT16_RS07235	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AAT16_RS07240	COG0022	dehydrogenase e1 component
AAT16_RS07245	COG0508	dehydrogenase complex catalyzes the overall conversion of
AAT16_RS07255	COG2195	Cleaves the N-terminal amino acid of tripeptides
AAT16_RS07270	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AAT16_RS07275	COG1234	tRNA 3'-trailer cleavage
AAT16_RS07280	COG1073	alpha beta
AAT16_RS07285	COG0667	Aldo Keto reductase
AAT16_RS07295	COG0735	belongs to the Fur family
AAT16_RS07300	COG4974	Belongs to the 'phage' integrase family
AAT16_RS07305	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AAT16_RS07315	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AAT16_RS07325	COG1187	pseudouridine synthase activity
AAT16_RS07330	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AAT16_RS07335	COG1333	cytochrome c biogenesis protein
AAT16_RS07340	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AAT16_RS07345	COG0745	RESPONSE REGULATOR receiver
AAT16_RS07350	COG5002	protein histidine kinase activity
AAT16_RS07360	COG1141	Ferredoxin
AAT16_RS07365	COG1388	LysM domain
AAT16_RS07370	COG0492	ferredoxin-NADP+ reductase activity
AAT16_RS07380	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AAT16_RS07390	COG0539	negative regulation of cytoplasmic translation
AAT16_RS07400	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AAT16_RS07435	COG0105	UTP biosynthetic process
AAT16_RS07445	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AAT16_RS07450	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AAT16_RS07455	COG0457	Tetratricopeptide repeat
AAT16_RS07460	COG5582	Belongs to the UPF0302 family
AAT16_RS07470	COG0723	plastoquinol--plastocyanin reductase activity
AAT16_RS07475	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AAT16_RS07485	COG4347	Protein of unknown function (DUF1405)
AAT16_RS07490	COG2738	Putative neutral zinc metallopeptidase
AAT16_RS07500	COG1803	Methylglyoxal synthase
AAT16_RS07505	COG0438	transferase activity, transferring glycosyl groups
AAT16_RS07510	COG0617	tRNA 3'-terminal CCA addition
AAT16_RS07515	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AAT16_RS07515	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AAT16_RS07520	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AAT16_RS07520	COG1199	ATP-dependent helicase activity
AAT16_RS07525	COG0436	Aminotransferase
AAT16_RS07530	COG0017	Asparaginyl-tRNA synthetase
AAT16_RS07540	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AAT16_RS07550	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AAT16_RS07550	COG4499	WXG100 protein secretion system (Wss), protein YukC
AAT16_RS07565	COG4474	Belongs to the UPF0398 family
AAT16_RS07570	COG3599	regulation of cell shape
AAT16_RS07575	COG0116	Belongs to the methyltransferase superfamily
AAT16_RS07580	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AAT16_RS07590	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AAT16_RS07600	COG1413	lyase activity
AAT16_RS07605	COG1413	lyase activity
AAT16_RS07635	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AAT16_RS07640	COG2190	(PTS) system
AAT16_RS07650	COG0813	purine-nucleoside phosphorylase activity
AAT16_RS07655	COG0793	Belongs to the peptidase S41A family
AAT16_RS07660	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AAT16_RS07665	COG0671	phosphoesterase, PA-phosphatase related
AAT16_RS07675	COG5002	protein histidine kinase activity
AAT16_RS07680	COG0567	Dehydrogenase, E1 component
AAT16_RS07695	COG0714	Associated with various cellular activities
AAT16_RS07700	COG4548	von Willebrand factor, type A
AAT16_RS07705	COG1114	Component of the transport system for branched-chain amino acids
AAT16_RS07710	COG3853	Toxic anion resistance protein (TelA)
AAT16_RS07715	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
AAT16_RS07720	COG1254	Belongs to the acylphosphatase family
AAT16_RS07730	COG1278	Cold shock
AAT16_RS07745	COG1473	amidohydrolase
AAT16_RS07750	COG2171	N-acyltransferase activity
AAT16_RS07755	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AAT16_RS07765	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AAT16_RS07770	COG0527	aspartate kinase activity
AAT16_RS07775	COG0488	(ABC) transporter
AAT16_RS07780	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AAT16_RS07805	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AAT16_RS07840	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AAT16_RS07870	COG1902	pentaerythritol trinitrate reductase activity
AAT16_RS07875	COG1115	amino acid carrier protein
AAT16_RS07880	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AAT16_RS07890	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AAT16_RS07895	COG4841	protein insertion into membrane
AAT16_RS07900	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AAT16_RS07905	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AAT16_RS07910	COG1970	mechanosensitive ion channel activity
AAT16_RS07915	COG1288	antiporter activity
AAT16_RS07920	COG1288	antiporter activity
AAT16_RS07925	COG0285	dihydrofolate synthase activity
AAT16_RS07945	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AAT16_RS07960	COG0181	hydroxymethylbilane synthase activity
AAT16_RS07965	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AAT16_RS07970	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AAT16_RS07975	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AAT16_RS07980	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AAT16_RS07985	COG0544	peptidyl-prolyl cis-trans isomerase activity
AAT16_RS07995	COG4112	unkown
AAT16_RS08045	COG3328	transposase activity
AAT16_RS08060	COG1966	Carbon starvation protein
AAT16_RS08070	COG0003	Pfam Anion-transporting ATPase
AAT16_RS08075	COG4297	protein containing double-stranded beta helix domain
AAT16_RS08080	COG1451	nucleotide metabolic process
AAT16_RS08085	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AAT16_RS08120	COG1028	Short-chain dehydrogenase reductase Sdr
AAT16_RS08125	COG1368	sulfuric ester hydrolase activity
AAT16_RS08140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AAT16_RS08165	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AAT16_RS08170	COG1846	Transcriptional regulator
AAT16_RS08175	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AAT16_RS08180	COG1053	succinate dehydrogenase
AAT16_RS08185	COG2009	succinate dehydrogenase
AAT16_RS08190	COG0322	excinuclease ABC activity
AAT16_RS08200	COG1193	negative regulation of DNA recombination
AAT16_RS08205	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AAT16_RS08205	COG1796	DNA polymerase
AAT16_RS08210	COG1286	toxin biosynthetic process
AAT16_RS08215	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AAT16_RS08220	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AAT16_RS08225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AAT16_RS08225	COG0072	phenylalanine-tRNA ligase activity
AAT16_RS08230	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AAT16_RS08235	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AAT16_RS08240	COG1363	Peptidase, m42
AAT16_RS08250	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AAT16_RS08255	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AAT16_RS08260	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AAT16_RS08265	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AAT16_RS08270	COG1484	DNA-dependent DNA replication
AAT16_RS08280	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AAT16_RS08290	COG0237	dephospho-CoA kinase activity
AAT16_RS08295	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AAT16_RS08300	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AAT16_RS08300	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AAT16_RS08305	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AAT16_RS08310	COG0039	L-malate dehydrogenase activity
AAT16_RS08315	COG0538	isocitrate dehydrogenase activity
AAT16_RS08320	COG0372	Belongs to the citrate synthase family
AAT16_RS08325	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AAT16_RS08340	COG0469	pyruvate kinase activity
AAT16_RS08345	COG0205	6-phosphofructokinase activity
AAT16_RS08365	COG0281	malic enzyme
AAT16_RS08370	COG0587	DNA-directed DNA polymerase activity
AAT16_RS08375	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AAT16_RS08385	COG4109	DRTGG domain
AAT16_RS08390	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AAT16_RS08410	COG0589	response to stress
AAT16_RS08415	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AAT16_RS08425	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AAT16_RS08430	COG1714	RDD family
AAT16_RS08435	COG0616	signal peptide processing
AAT16_RS08440	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AAT16_RS08450	COG0301	tRNA thio-modification
AAT16_RS08455	COG1104	cysteine desulfurase activity
AAT16_RS08460	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
AAT16_RS08465	COG1956	GAF domain-containing protein
AAT16_RS08470	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AAT16_RS08475	COG0569	domain protein
AAT16_RS08495	COG2323	membrane
AAT16_RS08525	COG2755	lipolytic protein G-D-S-L family
AAT16_RS08525	COG0657	acetylesterase activity
AAT16_RS08540	COG0406	alpha-ribazole phosphatase activity
AAT16_RS08545	COG1966	Carbon starvation protein
AAT16_RS08555	COG2323	membrane
AAT16_RS08560	COG0577	efflux transmembrane transporter activity
AAT16_RS08565	COG1136	(ABC) transporter
AAT16_RS08570	COG0642	Histidine kinase
AAT16_RS08575	COG0745	RESPONSE REGULATOR receiver
AAT16_RS08580	COG2311	Membrane
AAT16_RS08590	COG2814	Major facilitator Superfamily
AAT16_RS08610	COG3314	Sporulation integral membrane protein YlbJ
AAT16_RS08630	COG0492	ferredoxin-NADP+ reductase activity
AAT16_RS08640	COG1704	LemA family
AAT16_RS08655	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AAT16_RS08660	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AAT16_RS08665	COG0454	-acetyltransferase
AAT16_RS08670	COG0517	IMP dehydrogenase activity
AAT16_RS08675	COG0123	including yeast histone deacetylase and acetoin utilization protein
AAT16_RS08680	COG1609	Transcriptional regulator
AAT16_RS08685	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AAT16_RS08685	COG1605	Chorismate mutase
AAT16_RS08695	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
AAT16_RS08700	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AAT16_RS08710	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AAT16_RS08715	COG4848	Belongs to the UPF0354 family
AAT16_RS08725	COG1363	Peptidase, m42
AAT16_RS08735	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AAT16_RS08740	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AAT16_RS08745	COG0510	thiamine kinase activity
AAT16_RS08765	COG1187	pseudouridine synthase activity
AAT16_RS08770	COG2244	polysaccharide biosynthetic process
AAT16_RS08775	COG2081	HI0933 family
AAT16_RS08780	COG0495	leucyl-tRNA aminoacylation
AAT16_RS08785	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AAT16_RS08795	COG1131	(ABC) transporter
AAT16_RS08800	COG1242	4 iron, 4 sulfur cluster binding
AAT16_RS08805	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AAT16_RS08810	COG2267	carboxylic ester hydrolase activity
AAT16_RS08815	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AAT16_RS08820	COG0506	proline dehydrogenase activity
AAT16_RS08830	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AAT16_RS08840	COG1012	belongs to the aldehyde dehydrogenase family
AAT16_RS08860	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AAT16_RS08875	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AAT16_RS08880	COG0318	PFAM AMP-dependent synthetase and ligase
AAT16_RS08885	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AAT16_RS08890	COG0596	Alpha beta hydrolase
AAT16_RS08895	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AAT16_RS08900	COG1169	isochorismate synthase
AAT16_RS08905	COG1575	Belongs to the MenA family. Type 1 subfamily
AAT16_RS08920	COG2521	methyltransferase
AAT16_RS08920	COG2136	Putative SAM-dependent methyltransferase
AAT16_RS08925	COG0183	Belongs to the thiolase family
AAT16_RS08935	COG1960	acyl-CoA dehydrogenase activity
AAT16_RS08940	COG0318	PFAM AMP-dependent synthetase and ligase
AAT16_RS09115	COG0305	Participates in initiation and elongation during chromosome replication
AAT16_RS09285	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AAT16_RS09285	COG0723	plastoquinol--plastocyanin reductase activity
AAT16_RS09295	COG0789	Transcriptional regulator
AAT16_RS09310	COG1733	regulation of RNA biosynthetic process
AAT16_RS09315	COG2514	catechol 2,3-dioxygenase activity
AAT16_RS09320	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AAT16_RS09460	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AAT16_RS09465	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AAT16_RS09470	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AAT16_RS09480	COG4473	ABC transporter
AAT16_RS09485	COG1131	(ABC) transporter
AAT16_RS09490	COG0537	adenosine 5'-monophosphoramidase activity
AAT16_RS09500	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AAT16_RS09510	COG4717	serine-type aminopeptidase activity
AAT16_RS09515	COG0420	3'-5' exonuclease activity
AAT16_RS09520	COG3679	Belongs to the UPF0342 family
AAT16_RS09525	COG4399	Belongs to the UPF0754 family
AAT16_RS09535	COG1301	dicarboxylic acid transport
AAT16_RS09540	COG2197	response regulator
AAT16_RS09545	COG4585	Histidine kinase
AAT16_RS09545	COG2203	Gaf domain
AAT16_RS09550	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AAT16_RS09555	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AAT16_RS09560	COG0564	pseudouridine synthase activity
AAT16_RS09565	COG0512	Glutamine amidotransferase of anthranilate synthase
AAT16_RS09570	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AAT16_RS09575	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AAT16_RS09585	COG0114	fumarate hydratase activity
AAT16_RS09595	COG0363	glucosamine-6-phosphate deaminase activity
AAT16_RS09600	COG0778	Nitroreductase
AAT16_RS09610	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AAT16_RS09615	COG0488	(ABC) transporter
AAT16_RS09630	COG1418	mRNA catabolic process
AAT16_RS09645	COG1404	Belongs to the peptidase S8 family
AAT16_RS09650	COG2897	thiosulfate sulfurtransferase activity
AAT16_RS09815	COG0735	belongs to the Fur family
AAT16_RS09820	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AAT16_RS09825	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AAT16_RS09830	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AAT16_RS09835	COG4129	membrane
AAT16_RS09850	COG3557	Belongs to the UPF0374 family
AAT16_RS09860	COG1988	membrane-bound metal-dependent
AAT16_RS09880	COG2137	regulation of response to DNA damage stimulus
AAT16_RS09885	COG1607	acyl-coa hydrolase
AAT16_RS09890	COG2309	aminopeptidase activity
AAT16_RS09905	COG1295	ribonuclease BN
AAT16_RS09910	COG0288	reversible hydration of carbon dioxide
AAT16_RS09925	COG4129	membrane
AAT16_RS09930	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AAT16_RS09945	COG0745	RESPONSE REGULATOR receiver
AAT16_RS09950	COG5002	protein histidine kinase activity
AAT16_RS09950	COG3850	Histidine kinase
AAT16_RS09960	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AAT16_RS09990	COG1764	response to oxidative stress
AAT16_RS09995	COG1525	nuclease
AAT16_RS10005	COG1174	glycine betaine transport
AAT16_RS10035	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AAT16_RS10045	COG2084	Dehydrogenase
AAT16_RS10070	COG1028	Short-chain dehydrogenase reductase Sdr
AAT16_RS10080	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AAT16_RS10085	COG0798	PFAM Bile acid sodium symporter
AAT16_RS10090	COG5646	InterPro IPR014922
AAT16_RS10110	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AAT16_RS10130	COG0346	lactoylglutathione lyase activity
AAT16_RS10135	COG1119	ATPase activity
AAT16_RS10140	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AAT16_RS10150	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AAT16_RS10185	COG0737	Belongs to the 5'-nucleotidase family
AAT16_RS10200	COG1597	lipid kinase activity
AAT16_RS10215	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AAT16_RS10220	COG0154	amidase activity
AAT16_RS10225	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AAT16_RS10235	COG4851	CamS sex pheromone cAM373 precursor
AAT16_RS10240	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AAT16_RS10250	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
AAT16_RS10255	COG1876	peptidase activity
AAT16_RS10260	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AAT16_RS10280	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AAT16_RS10285	COG0477	Major facilitator Superfamily
AAT16_RS10290	COG1335	isochorismatase
AAT16_RS10295	COG1227	inorganic diphosphatase activity
AAT16_RS10310	COG2706	6-phosphogluconolactonase activity
AAT16_RS10320	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AAT16_RS10335	COG0432	Pfam Uncharacterised protein family UPF0047
AAT16_RS10340	COG4876	unkown
AAT16_RS10350	COG0494	nUDIX hydrolase
AAT16_RS10375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AAT16_RS10375	COG1263	PTS System
AAT16_RS10380	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AAT16_RS10400	COG1012	belongs to the aldehyde dehydrogenase family
AAT16_RS10425	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AAT16_RS10450	COG1132	(ABC) transporter
AAT16_RS10455	COG4152	abc transporter atp-binding protein
AAT16_RS10460	COG1668	transmembrane transport
AAT16_RS10475	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AAT16_RS10480	COG0747	negative chemotaxis
AAT16_RS10485	COG4336	lyase activity
AAT16_RS10490	COG1914	H( )-stimulated, divalent metal cation uptake system
AAT16_RS10495	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AAT16_RS10500	COG0439	Biotin carboxylase
AAT16_RS10510	COG1984	allophanate hydrolase subunit 2
AAT16_RS10515	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AAT16_RS10520	COG1811	Na channel or pump
AAT16_RS10535	COG3173	Aminoglycoside phosphotransferase
AAT16_RS10540	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AAT16_RS10550	COG2207	Transcriptional regulator
AAT16_RS10550	COG3708	Transcriptional regulator
AAT16_RS10570	COG1621	beta-fructofuranosidase activity
AAT16_RS10585	COG2226	methyltransferase
AAT16_RS10595	COG3001	Fructosamine kinase
AAT16_RS10605	COG1250	3-hydroxyacyl-CoA dehydrogenase
AAT16_RS10610	COG3246	L-lysine catabolic process to acetate
AAT16_RS10640	COG0788	formyltetrahydrofolate deformylase activity
AAT16_RS10645	COG1028	Short-chain dehydrogenase reductase Sdr
AAT16_RS10655	COG1959	2 iron, 2 sulfur cluster binding
AAT16_RS10660	COG0300	oxidoreductase activity
AAT16_RS10670	COG1028	Short-chain dehydrogenase reductase Sdr
AAT16_RS10675	COG4667	esterase of the alpha-beta hydrolase superfamily
AAT16_RS10680	COG1725	Transcriptional regulator
AAT16_RS10685	COG1131	(ABC) transporter
AAT16_RS10695	COG2076	Multidrug Resistance protein
AAT16_RS10700	COG2076	Multidrug Resistance protein
AAT16_RS10755	COG0583	DNA-binding transcription factor activity
AAT16_RS10775	COG1063	alcohol dehydrogenase
AAT16_RS10795	COG0659	secondary active sulfate transmembrane transporter activity
AAT16_RS10800	COG0589	response to stress
AAT16_RS10825	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AAT16_RS10840	COG0640	Transcriptional regulator
AAT16_RS10855	COG0730	response to heat
AAT16_RS10860	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AAT16_RS10865	COG2210	Belongs to the sulfur carrier protein TusA family
AAT16_RS10870	COG1937	Protein conserved in bacteria
AAT16_RS10900	COG0785	Cytochrome C biogenesis protein
AAT16_RS10905	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AAT16_RS10935	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AAT16_RS10950	COG2190	(PTS) system
AAT16_RS10950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AAT16_RS10950	COG1263	PTS System
AAT16_RS10960	COG0702	epimerase
AAT16_RS10965	COG3279	Response regulator of the LytR AlgR family
AAT16_RS11005	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AAT16_RS11015	COG2155	Conserved Protein
AAT16_RS11020	COG1228	amidohydrolase
AAT16_RS11030	COG0469	pyruvate kinase activity
AAT16_RS11040	COG3973	AAA domain
AAT16_RS11045	COG1823	symporter activity
AAT16_RS11060	COG2153	protein acetylation
AAT16_RS11065	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AAT16_RS11070	COG2226	methyltransferase
AAT16_RS11085	COG2814	Major facilitator Superfamily
AAT16_RS11090	COG2814	Major facilitator Superfamily
AAT16_RS11100	COG2814	Major facilitator Superfamily
AAT16_RS11105	COG2195	Cleaves the N-terminal amino acid of tripeptides
AAT16_RS11115	COG1247	-acetyltransferase
AAT16_RS11120	COG1051	belongs to the nudix hydrolase family
AAT16_RS11125	COG1181	Belongs to the D-alanine--D-alanine ligase family
AAT16_RS11135	COG1132	(ABC) transporter
AAT16_RS11145	COG0077	Prephenate dehydratase
AAT16_RS11145	COG1605	Chorismate mutase
AAT16_RS11150	COG1301	dicarboxylic acid transport
AAT16_RS11155	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AAT16_RS11185	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AAT16_RS11190	COG2233	PERMEase
AAT16_RS11210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AAT16_RS11215	COG0601	transmembrane transport
AAT16_RS11225	COG0829	nickel cation binding
AAT16_RS11230	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AAT16_RS11235	COG0830	nickel cation binding
AAT16_RS11240	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AAT16_RS11250	COG0832	Belongs to the urease beta subunit family
AAT16_RS11255	COG0831	urea catabolic process
AAT16_RS11270	COG0584	glycerophosphoryl diester phosphodiesterase
AAT16_RS11275	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AAT16_RS11280	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AAT16_RS11295	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AAT16_RS11300	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AAT16_RS11305	COG1609	Transcriptional regulator
AAT16_RS11320	COG1278	Cold shock
AAT16_RS11325	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AAT16_RS11330	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AAT16_RS11345	COG1876	peptidase activity
AAT16_RS11350	COG1609	Transcriptional regulator
AAT16_RS11355	COG1082	Xylose isomerase domain protein TIM barrel
AAT16_RS11360	COG1172	Belongs to the binding-protein-dependent transport system permease family
AAT16_RS11365	COG1129	ABC transporter
AAT16_RS11370	COG0673	inositol 2-dehydrogenase activity
AAT16_RS11380	COG0673	inositol 2-dehydrogenase activity
AAT16_RS11395	COG0459	protein refolding
AAT16_RS11400	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AAT16_RS11405	COG1266	CAAX protease self-immunity
AAT16_RS11425	COG1737	Transcriptional regulator
AAT16_RS11430	COG1621	beta-fructofuranosidase activity
AAT16_RS11435	COG0805	protein transport
AAT16_RS11440	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AAT16_RS11445	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AAT16_RS11450	COG0488	(ABC) transporter
AAT16_RS11460	COG0456	acetyltransferase
AAT16_RS11465	COG1214	PFAM Peptidase M22, glycoprotease
AAT16_RS11470	COG0802	atpase or kinase
AAT16_RS11505	COG0753	catalase activity
AAT16_RS11510	COG1854	S-ribosylhomocysteine lyase activity
AAT16_RS11515	COG2183	response to ionizing radiation
AAT16_RS11520	COG1191	sigma factor activity
AAT16_RS11530	COG1366	Belongs to the anti-sigma-factor antagonist family
AAT16_RS11535	COG2208	phosphoserine phosphatase activity
AAT16_RS11550	COG0736	holo-[acyl-carrier-protein] synthase activity
AAT16_RS11570	COG0513	Belongs to the DEAD box helicase family
AAT16_RS11580	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AAT16_RS11585	COG0772	Belongs to the SEDS family
AAT16_RS11595	COG0706	membrane insertase activity
AAT16_RS11600	COG0352	thiamine-phosphate diphosphorylase activity
AAT16_RS11615	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AAT16_RS11620	COG3584	3D domain protein
AAT16_RS11620	COG1388	LysM domain
AAT16_RS11635	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AAT16_RS11645	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AAT16_RS11655	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AAT16_RS11660	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AAT16_RS11665	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AAT16_RS11670	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AAT16_RS11675	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AAT16_RS11680	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AAT16_RS11685	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AAT16_RS11690	COG0356	it plays a direct role in the translocation of protons across the membrane
AAT16_RS11700	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AAT16_RS11705	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AAT16_RS11710	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AAT16_RS11715	COG4475	Protein of unknown function (DUF436)
AAT16_RS11720	COG0698	ribose 5-phosphate isomerase
AAT16_RS11725	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AAT16_RS11730	COG0009	L-threonylcarbamoyladenylate synthase
AAT16_RS11735	COG2890	protein-(glutamine-N5) methyltransferase activity
AAT16_RS11740	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AAT16_RS11745	COG0254	rRNA binding
AAT16_RS11750	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AAT16_RS11755	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AAT16_RS11760	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AAT16_RS11780	COG3343	RNA polymerase activity
AAT16_RS11785	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AAT16_RS11795	COG5146	pantothenate kinase activity
AAT16_RS11800	COG3842	ATPase activity
AAT16_RS11815	COG1765	OsmC-like protein
AAT16_RS11820	COG1914	H( )-stimulated, divalent metal cation uptake system
AAT16_RS11825	COG0010	Belongs to the arginase family
AAT16_RS11830	COG0640	Transcriptional regulator
AAT16_RS11835	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AAT16_RS11840	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AAT16_RS11855	COG1929	Belongs to the glycerate kinase type-1 family
AAT16_RS11860	COG0656	L-ascorbic acid biosynthetic process
AAT16_RS11870	COG0728	peptidoglycan biosynthetic process
AAT16_RS11875	COG0436	Aminotransferase
AAT16_RS11880	COG2059	Chromate
AAT16_RS11885	COG2059	Chromate
AAT16_RS11890	COG0405	Gamma-glutamyltransferase
AAT16_RS11895	COG0653	protein targeting
AAT16_RS11915	COG0561	phosphatase activity
AAT16_RS11920	COG0400	carboxylic ester hydrolase activity
AAT16_RS11925	COG0346	lactoylglutathione lyase activity
AAT16_RS11930	COG1737	Transcriptional regulator
AAT16_RS11935	COG1263	PTS System
AAT16_RS11935	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AAT16_RS11940	COG1486	melibiose metabolic process
AAT16_RS11945	COG2197	response regulator
AAT16_RS11950	COG4585	Histidine kinase
AAT16_RS11955	COG1131	(ABC) transporter
AAT16_RS11980	COG2962	Rard protein
AAT16_RS11995	COG3711	transcriptional antiterminator
AAT16_RS12005	COG0246	Mannitol dehydrogenase
AAT16_RS12010	COG0753	catalase activity
AAT16_RS12020	COG2409	Drug exporters of the RND superfamily
AAT16_RS12020	COG1033	growth of symbiont in host cell
AAT16_RS12035	COG2133	pyrroloquinoline quinone binding
AAT16_RS12040	COG1473	amidohydrolase
AAT16_RS12045	COG1288	antiporter activity
AAT16_RS12050	COG4948	Mandelate Racemase Muconate Lactonizing
AAT16_RS12055	COG1408	metallophosphoesterase
AAT16_RS12060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AAT16_RS12065	COG4989	oxidoreductase activity
AAT16_RS12085	COG1253	flavin adenine dinucleotide binding
AAT16_RS12095	COG2217	Heavy metal translocating P-type atpase
AAT16_RS12100	COG1937	Protein conserved in bacteria
AAT16_RS12105	COG2124	cytochrome p450
AAT16_RS12110	COG2079	MmgE PrpD family protein
AAT16_RS12115	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AAT16_RS12130	COG3181	Tripartite tricarboxylate transporter family receptor
AAT16_RS12135	COG4565	transcriptional regulatory protein
AAT16_RS12140	COG3290	protein histidine kinase activity
AAT16_RS12155	COG0583	DNA-binding transcription factor activity
AAT16_RS12170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AAT16_RS12170	COG1263	PTS System
AAT16_RS12170	COG2190	(PTS) system
AAT16_RS12175	COG3711	transcriptional antiterminator
AAT16_RS12190	COG1733	regulation of RNA biosynthetic process
AAT16_RS12195	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AAT16_RS12200	COG2011	ABC-type metal ion transport system permease component
AAT16_RS12205	COG1464	Belongs to the NlpA lipoprotein family
AAT16_RS12210	COG2814	Major facilitator Superfamily
AAT16_RS12220	COG0493	'glutamate synthase
AAT16_RS12225	COG0070	glutamate synthase
AAT16_RS12225	COG0067	glutamate synthase
AAT16_RS12225	COG0069	glutamate synthase activity
AAT16_RS12230	COG0583	DNA-binding transcription factor activity
AAT16_RS12250	COG0473	3-isopropylmalate dehydrogenase activity
AAT16_RS12260	COG0579	oxidoreductase
AAT16_RS12265	COG1620	l-lactate permease
AAT16_RS12270	COG2186	Transcriptional regulator
AAT16_RS12275	COG1966	Carbon starvation protein
AAT16_RS12285	COG3971	2-oxopent-4-enoate hydratase activity
AAT16_RS12290	COG4187	Peptidase family M20/M25/M40
AAT16_RS12295	COG1115	amino acid carrier protein
AAT16_RS12305	COG1263	PTS System
AAT16_RS12305	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AAT16_RS12310	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AAT16_RS12330	COG0598	Magnesium transport protein CorA
AAT16_RS12335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AAT16_RS12345	COG1120	ATPase activity
AAT16_RS12350	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AAT16_RS12355	COG0492	ferredoxin-NADP+ reductase activity
AAT16_RS12360	COG0733	neurotransmitter:sodium symporter activity
AAT16_RS12370	COG1757	Na H antiporter
AAT16_RS12385	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AAT16_RS12420	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AAT16_RS12425	COG0346	lactoylglutathione lyase activity
AAT16_RS12430	COG0346	lactoylglutathione lyase activity
AAT16_RS12435	COG1846	Transcriptional regulator
AAT16_RS12455	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AAT16_RS12465	COG3732	PTS system glucitol sorbitol-specific
AAT16_RS12505	COG1063	alcohol dehydrogenase
AAT16_RS12515	COG1063	alcohol dehydrogenase
AAT16_RS12520	COG3775	system Galactitol-specific IIC component
AAT16_RS12525	COG3414	Phosphotransferase system galactitol-specific IIB component
AAT16_RS12555	COG0765	amino acid transport
AAT16_RS12560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AAT16_RS12565	COG1126	abc transporter atp-binding protein
AAT16_RS12570	COG1960	acyl-CoA dehydrogenase activity
AAT16_RS12580	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AAT16_RS12585	COG1757	Na H antiporter
AAT16_RS12595	COG3938	Belongs to the proline racemase family
AAT16_RS12600	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AAT16_RS12605	COG3829	transcription factor binding
AAT16_RS12605	COG3290	protein histidine kinase activity
AAT16_RS12625	COG0006	proline dipeptidase activity
AAT16_RS12640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AAT16_RS12645	COG0601	transmembrane transport
AAT16_RS12650	COG4166	transmembrane transport
AAT16_RS12660	COG0006	proline dipeptidase activity
AAT16_RS12665	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AAT16_RS12670	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AAT16_RS12680	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AAT16_RS12685	COG3620	sequence-specific DNA binding
AAT16_RS12690	COG1012	belongs to the aldehyde dehydrogenase family
AAT16_RS12710	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AAT16_RS12720	COG2814	Major facilitator Superfamily
AAT16_RS12725	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AAT16_RS12730	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AAT16_RS12735	COG1802	Transcriptional regulator
AAT16_RS12740	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AAT16_RS12750	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AAT16_RS12755	COG1063	alcohol dehydrogenase
AAT16_RS12760	COG1312	Catalyzes the dehydration of D-mannonate
AAT16_RS12765	COG1028	Short-chain dehydrogenase reductase Sdr
AAT16_RS12770	COG0006	proline dipeptidase activity
AAT16_RS12780	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AAT16_RS12785	COG0436	Aminotransferase
AAT16_RS12790	COG3314	Sporulation integral membrane protein YlbJ
AAT16_RS12800	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AAT16_RS12805	COG0730	response to heat
AAT16_RS12810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AAT16_RS12815	COG2210	Belongs to the sulfur carrier protein TusA family
AAT16_RS12820	COG1937	Protein conserved in bacteria
AAT16_RS12830	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AAT16_RS12835	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AAT16_RS12840	COG1447	Phosphotransferase system cellobiose-specific component IIA
AAT16_RS12845	COG2723	6-phospho-beta-galactosidase activity
AAT16_RS12850	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AAT16_RS12850	COG3711	transcriptional antiterminator
AAT16_RS12860	COG5505	Protein of unknown function (DUF819)
AAT16_RS12865	COG1482	cell wall glycoprotein biosynthetic process
AAT16_RS12875	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AAT16_RS12875	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AAT16_RS12875	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AAT16_RS12880	COG2258	MOSC domain
AAT16_RS12905	COG2610	gluconate transmembrane transporter activity
AAT16_RS12910	COG4948	Mandelate Racemase Muconate Lactonizing
AAT16_RS12915	COG0800	Aldolase
AAT16_RS12945	COG1414	Transcriptional regulator
AAT16_RS12950	COG4145	pantothenate transmembrane transporter activity
AAT16_RS12975	COG2610	gluconate transmembrane transporter activity
AAT16_RS12985	COG2084	Dehydrogenase
AAT16_RS12990	COG1802	Transcriptional regulator
AAT16_RS13020	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AAT16_RS13025	COG2814	Major facilitator Superfamily
AAT16_RS13035	COG2226	methyltransferase
AAT16_RS13040	COG1609	Transcriptional regulator
AAT16_RS13045	COG0800	Aldolase
AAT16_RS13070	COG1904	glucuronate isomerase
AAT16_RS13075	COG2814	Major facilitator Superfamily
AAT16_RS13080	COG0824	Thioesterase
AAT16_RS13090	COG1929	Belongs to the glycerate kinase type-1 family
AAT16_RS13105	COG1757	Na H antiporter
AAT16_RS13110	COG0702	epimerase
AAT16_RS13120	COG0697	spore germination
AAT16_RS13140	COG0110	maltose O-acetyltransferase activity
AAT16_RS13145	COG0823	Involved in the tonB-independent uptake of proteins
AAT16_RS13145	COG1506	peptidase
AAT16_RS13145	COG4946	Tricorn protease homolog
AAT16_RS13150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AAT16_RS13155	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AAT16_RS13170	COG2239	Acts as a magnesium transporter
AAT16_RS13180	COG1078	dGTPase activity
AAT16_RS13190	COG0095	Lipoate-protein ligase
AAT16_RS13210	COG1131	(ABC) transporter
AAT16_RS13215	COG1609	Transcriptional regulator
AAT16_RS13225	COG2363	Small membrane protein
AAT16_RS13250	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AAT16_RS13255	COG1469	GTP cyclohydrolase I activity
AAT16_RS13265	COG0561	phosphatase activity
AAT16_RS13280	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AAT16_RS13290	COG1473	amidohydrolase
AAT16_RS13295	COG1473	amidohydrolase
AAT16_RS13300	COG1473	amidohydrolase
AAT16_RS13305	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AAT16_RS13310	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AAT16_RS13315	COG0049	tRNA binding
AAT16_RS13320	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AAT16_RS13325	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AAT16_RS13330	COG0085	RNA polymerase activity
AAT16_RS13340	COG0222	ribosome binding
AAT16_RS13345	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AAT16_RS13350	COG0081	regulation of translation
AAT16_RS13355	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AAT16_RS13375	COG3688	RNA-binding protein containing a PIN domain
AAT16_RS13380	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AAT16_RS13385	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AAT16_RS13390	COG0215	cysteine-tRNA ligase activity
AAT16_RS13395	COG1045	serine acetyltransferase
AAT16_RS13415	COG4956	integral membrane protein (PIN domain superfamily)
AAT16_RS13420	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AAT16_RS13425	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AAT16_RS13430	COG0542	response to heat
AAT16_RS13435	COG3869	Catalyzes the specific phosphorylation of arginine residues in
AAT16_RS13440	COG3880	PFAM UvrB UvrC protein
AAT16_RS13450	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AAT16_RS13455	COG0454	-acetyltransferase
AAT16_RS13465	COG4496	protein, YerC YecD
AAT16_RS13475	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AAT16_RS13480	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AAT16_RS13485	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AAT16_RS13490	COG0131	Imidazoleglycerol-phosphate dehydratase
AAT16_RS13500	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AAT16_RS13505	COG0107	imidazoleglycerol-phosphate synthase activity
AAT16_RS13535	COG1116	anion transmembrane transporter activity
AAT16_RS13550	COG1114	Component of the transport system for branched-chain amino acids
AAT16_RS13555	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AAT16_RS13560	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
AAT16_RS13565	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AAT16_RS13615	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AAT16_RS13620	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AAT16_RS13635	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AAT16_RS13640	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AAT16_RS13645	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AAT16_RS13660	COG1098	S1 RNA binding domain
AAT16_RS13670	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AAT16_RS13675	COG3956	TIGRFAM MazG family protein
AAT16_RS13680	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AAT16_RS13690	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AAT16_RS13695	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AAT16_RS13700	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AAT16_RS13705	COG2088	sporulation resulting in formation of a cellular spore
AAT16_RS13710	COG0251	oxidation-reduction process
AAT16_RS13715	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AAT16_RS13720	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AAT16_RS13740	COG3279	Response regulator of the LytR AlgR family
AAT16_RS13750	COG4466	Protein conserved in bacteria
AAT16_RS13755	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AAT16_RS13760	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AAT16_RS13765	COG0084	hydrolase, TatD family'
AAT16_RS13770	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AAT16_RS13770	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AAT16_RS13775	COG2002	toxin-antitoxin pair type II binding
AAT16_RS13780	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AAT16_RS13790	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AAT16_RS13795	COG4467	Involved in initiation control of chromosome replication
AAT16_RS13800	COG1774	PSP1 C-terminal conserved region
AAT16_RS13810	COG3870	Protein conserved in bacteria
AAT16_RS13820	COG1982	Orn Lys Arg decarboxylase major
AAT16_RS13840	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AAT16_RS13845	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AAT16_RS13850	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AAT16_RS13855	COG2188	Transcriptional regulator
AAT16_RS13860	COG0366	Alpha amylase catalytic
AAT16_RS13865	COG1263	PTS System
AAT16_RS13865	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AAT16_RS13870	COG0004	ammonium transporteR
AAT16_RS13880	COG0456	acetyltransferase
AAT16_RS13885	COG2808	Putative FMN-binding domain
AAT16_RS13905	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AAT16_RS13910	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AAT16_RS13950	COG0785	Cytochrome C biogenesis protein
AAT16_RS13965	COG1388	LysM domain
AAT16_RS13975	COG3850	Histidine kinase
AAT16_RS13975	COG5002	protein histidine kinase activity
AAT16_RS13980	COG0745	RESPONSE REGULATOR receiver
AAT16_RS14005	COG1388	LysM domain
AAT16_RS14010	COG2132	Multicopper oxidase
AAT16_RS14055	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AAT16_RS14080	COG0515	serine threonine protein kinase
AAT16_RS14080	COG2815	serine threonine protein kinase
AAT16_RS14105	COG2032	superoxide dismutase activity
AAT16_RS14110	COG0791	NLP P60 protein
AAT16_RS14110	COG3103	Sh3 type 3 domain protein
AAT16_RS14110	COG1388	LysM domain
AAT16_RS14130	COG3942	CHAP domain
AAT16_RS14130	COG1388	LysM domain
AAT16_RS14140	COG0596	Alpha beta hydrolase
AAT16_RS14160	COG1705	Flagellar rod assembly protein muramidase FlgJ
AAT16_RS14210	COG1124	(ABC) transporter