locus-tag	class	description
HPG92_RS00095	COG1556	Lactate utilization protein
HPG92_RS00100	COG1139	Iron-sulfur cluster binding protein
HPG92_RS00105	COG0247	lactate metabolic process
HPG92_RS00110	COG1620	l-lactate permease
HPG92_RS00145	COG2068	MobA-Related Protein
HPG92_RS00155	COG2233	PERMEase
HPG92_RS00165	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HPG92_RS00170	COG0402	S-adenosylhomocysteine deaminase activity
HPG92_RS00175	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HPG92_RS00175	COG0493	'glutamate synthase
HPG92_RS00180	COG3608	succinylglutamate desuccinylase aspartoacylase
HPG92_RS00180	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HPG92_RS00185	COG0549	Belongs to the carbamate kinase family
HPG92_RS00195	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HPG92_RS00200	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HPG92_RS00205	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HPG92_RS00225	COG1487	ribonuclease activity
HPG92_RS00295	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
HPG92_RS00405	COG1487	ribonuclease activity
HPG92_RS00500	COG2801	Transposase and inactivated derivatives
HPG92_RS00565	COG4974	Belongs to the 'phage' integrase family
HPG92_RS00570	COG0582	viral genome integration into host DNA
HPG92_RS00575	COG4974	Belongs to the 'phage' integrase family
HPG92_RS00680	COG1363	Peptidase, m42
HPG92_RS00735	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HPG92_RS00750	COG1454	alcohol dehydrogenase
HPG92_RS00785	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HPG92_RS00795	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HPG92_RS00800	COG2258	MOSC domain
HPG92_RS00805	COG2205	protein histidine kinase activity
HPG92_RS00810	COG0745	RESPONSE REGULATOR receiver
HPG92_RS00815	COG3678	ATP-independent chaperone mediated protein folding
HPG92_RS00925	COG2771	luxR family
HPG92_RS00925	COG2200	EAL domain
HPG92_RS00985	COG0471	metal ion transport
HPG92_RS01000	COG3152	Membrane
HPG92_RS01010	COG1494	fructose-1,6-bisphosphatase
HPG92_RS01020	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HPG92_RS01035	COG1575	Belongs to the MenA family. Type 1 subfamily
HPG92_RS01050	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HPG92_RS01055	COG1609	Transcriptional regulator
HPG92_RS01060	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HPG92_RS01075	COG2211	Major facilitator Superfamily
HPG92_RS01085	COG0626	cystathionine gamma-synthase activity
HPG92_RS01090	COG0527	aspartate kinase activity
HPG92_RS01090	COG0460	homoserine dehydrogenase
HPG92_RS01110	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
HPG92_RS01115	COG3738	Protein conserved in bacteria
HPG92_RS01120	COG0371	Dehydrogenase
HPG92_RS01130	COG2207	Transcriptional regulator
HPG92_RS01165	COG0583	DNA-binding transcription factor activity
HPG92_RS01270	COG0250	Participates in transcription elongation, termination and antitermination
HPG92_RS01315	COG1447	Phosphotransferase system cellobiose-specific component IIA
HPG92_RS01335	COG2104	thiamine diphosphate biosynthetic process
HPG92_RS01340	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HPG92_RS01400	COG2204	response regulator
HPG92_RS01405	COG0151	Belongs to the GarS family
HPG92_RS01450	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HPG92_RS01500	COG3122	Protein conserved in bacteria
HPG92_RS01515	COG0527	aspartate kinase activity
HPG92_RS01540	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HPG92_RS01550	COG2814	Major facilitator Superfamily
HPG92_RS01550	COG0477	Major facilitator Superfamily
HPG92_RS01555	COG3833	ABC-type maltose transport systems, permease component
HPG92_RS01600	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HPG92_RS01610	COG0534	Mate efflux family protein
HPG92_RS01625	COG0735	belongs to the Fur family
HPG92_RS01635	COG1063	alcohol dehydrogenase
HPG92_RS01640	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HPG92_RS01670	COG3700	Belongs to the class B bacterial acid phosphatase family
HPG92_RS01680	COG2315	Protein conserved in bacteria
HPG92_RS01740	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HPG92_RS01760	COG2252	PERMEase
HPG92_RS01765	COG0025	NhaP-type Na H and K H
HPG92_RS01770	COG0583	DNA-binding transcription factor activity
HPG92_RS01775	COG1380	Effector of murein hydrolase LrgA
HPG92_RS01780	COG1346	cytolysis
HPG92_RS01790	COG3162	membrane
HPG92_RS01795	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HPG92_RS01805	COG1301	dicarboxylic acid transport
HPG92_RS01810	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HPG92_RS01825	COG1289	transmembrane transporter activity
HPG92_RS01830	COG1566	PFAM secretion protein HlyD family protein
HPG92_RS01840	COG2015	COG2015, Alkyl sulfatase and related hydrolases
HPG92_RS01850	COG2824	Alkylphosphonate utilization operon protein PhnA
HPG92_RS01880	COG0531	amino acid
HPG92_RS01885	COG2207	Transcriptional regulator
HPG92_RS01895	COG2169	Transcriptional regulator
HPG92_RS01910	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HPG92_RS01910	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HPG92_RS01915	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HPG92_RS01925	COG4565	transcriptional regulatory protein
HPG92_RS01930	COG3290	protein histidine kinase activity
HPG92_RS01940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HPG92_RS01945	COG4558	Periplasmic binding protein
HPG92_RS01950	COG3720	iron ion transport
HPG92_RS01955	COG4771	TonB-dependent receptor
HPG92_RS01960	COG4256	Hemin uptake protein
HPG92_RS01975	COG3204	pilus organization
HPG92_RS01980	COG2197	response regulator
HPG92_RS02010	COG1309	transcriptional regulator
HPG92_RS02025	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HPG92_RS02030	COG1027	Aspartate ammonia-lyase
HPG92_RS02040	COG0531	amino acid
HPG92_RS02080	COG5510	response to toxic substance
HPG92_RS02110	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HPG92_RS02115	COG1053	succinate dehydrogenase
HPG92_RS02150	COG3539	Fimbrial protein
HPG92_RS02155	COG3188	usher protein
HPG92_RS02160	COG3121	Chaperone
HPG92_RS02175	COG3264	Mechanosensitive ion channel
HPG92_RS02175	COG1511	domain protein
HPG92_RS02195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HPG92_RS02220	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HPG92_RS02220	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HPG92_RS02225	COG0802	atpase or kinase
HPG92_RS02250	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HPG92_RS02255	COG0330	HflC and HflK could
HPG92_RS02260	COG0330	HflC and HflK could
HPG92_RS02285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HPG92_RS02290	COG1136	(ABC) transporter
HPG92_RS02290	COG0577	efflux transmembrane transporter activity
HPG92_RS02300	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HPG92_RS02315	COG1028	Short-chain dehydrogenase reductase Sdr
HPG92_RS02320	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
HPG92_RS02335	COG0557	exoribonuclease II activity
HPG92_RS02345	COG1842	Phage shock protein A
HPG92_RS02350	COG1842	Phage shock protein A
HPG92_RS02365	COG1960	acyl-CoA dehydrogenase activity
HPG92_RS02375	COG3650	response to hydrogen peroxide
HPG92_RS02380	COG1073	alpha beta
HPG92_RS02405	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HPG92_RS02445	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HPG92_RS02460	COG3061	Opacity-associated protein A
HPG92_RS02465	COG0545	Peptidyl-prolyl cis-trans isomerase
HPG92_RS02470	COG1113	amino acid transport
HPG92_RS02480	COG0697	spore germination
HPG92_RS02485	COG0702	epimerase
HPG92_RS02490	COG1733	regulation of RNA biosynthetic process
HPG92_RS02505	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
HPG92_RS02515	COG1253	flavin adenine dinucleotide binding
HPG92_RS02535	COG2105	PFAM AIG2 family protein
HPG92_RS02545	COG0840	transmembrane signaling receptor activity
HPG92_RS02555	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HPG92_RS02565	COG0312	modulator of DNA gyrase
HPG92_RS02600	COG3964	amidohydrolase
HPG92_RS02615	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HPG92_RS02615	COG3711	transcriptional antiterminator
HPG92_RS02620	COG3077	Addiction module antitoxin, RelB DinJ family
HPG92_RS02625	COG2026	Addiction module toxin, RelE StbE family
HPG92_RS02640	COG0366	Alpha amylase catalytic
HPG92_RS02645	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HPG92_RS02645	COG1263	PTS System
HPG92_RS02690	COG1438	arginine binding
HPG92_RS02695	COG1288	antiporter activity
HPG92_RS02705	COG0549	Belongs to the carbamate kinase family
HPG92_RS02710	COG2235	arginine
HPG92_RS02715	COG2731	YhcH YjgK YiaL family protein
HPG92_RS02750	COG2927	DNA polymerase III (CHI subunit)
HPG92_RS02760	COG0795	lipopolysaccharide-transporting ATPase activity
HPG92_RS02765	COG0795	lipopolysaccharide-transporting ATPase activity
HPG92_RS02785	COG1064	alcohol dehydrogenase
HPG92_RS02795	COG0582	viral genome integration into host DNA
HPG92_RS02820	COG3177	Filamentation induced by cAMP protein fic
HPG92_RS02880	COG0582	viral genome integration into host DNA
HPG92_RS02885	COG3539	Fimbrial protein
HPG92_RS02890	COG3121	Chaperone
HPG92_RS02915	COG0673	inositol 2-dehydrogenase activity
HPG92_RS02920	COG3732	PTS system glucitol sorbitol-specific
HPG92_RS02940	COG1476	TRANSCRIPTIONal
HPG92_RS03075	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HPG92_RS03095	COG5492	domain, Protein
HPG92_RS03110	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
HPG92_RS03120	COG3716	PTS system mannose fructose sorbose family IID component
HPG92_RS03125	COG3715	PTS system
HPG92_RS03130	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HPG92_RS03150	COG2186	Transcriptional regulator
HPG92_RS03175	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HPG92_RS03180	COG0700	Nucleoside recognition
HPG92_RS03185	COG3366	ferrous iron transmembrane transporter activity
HPG92_RS03190	COG0477	Major facilitator Superfamily
HPG92_RS03195	COG2733	membrane
HPG92_RS03210	COG1012	belongs to the aldehyde dehydrogenase family
HPG92_RS03230	COG0732	type I restriction modification DNA specificity domain
HPG92_RS03245	COG1715	Restriction endonuclease
HPG92_RS03260	COG0523	cobalamin synthesis protein
HPG92_RS03265	COG2879	small protein
HPG92_RS03270	COG1966	Carbon starvation protein
HPG92_RS03275	COG0840	transmembrane signaling receptor activity
HPG92_RS03295	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HPG92_RS03300	COG3715	PTS system
HPG92_RS03305	COG3716	PTS system mannose fructose sorbose family IID component
HPG92_RS03310	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HPG92_RS03315	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HPG92_RS03330	COG1484	DNA-dependent DNA replication
HPG92_RS03345	COG2966	Psort location CytoplasmicMembrane, score
HPG92_RS03350	COG2197	response regulator
HPG92_RS03355	COG2197	response regulator
HPG92_RS03360	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HPG92_RS03365	COG4114	ferric iron reductase
HPG92_RS03370	COG3706	GGDEF domain
HPG92_RS03400	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
HPG92_RS03410	COG1011	Hydrolase
HPG92_RS03420	COG2823	Periplasmic or secreted lipoprotein
HPG92_RS03430	COG4667	esterase of the alpha-beta hydrolase superfamily
HPG92_RS03435	COG0084	hydrolase, TatD family'
HPG92_RS03440	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HPG92_RS03445	COG1328	CTP reductase activity
HPG92_RS03470	COG1943	Transposase
HPG92_RS03480	COG3726	membrane protein affecting hemolysin expression
HPG92_RS03485	COG0560	Phosphoserine phosphatase
HPG92_RS03500	COG0488	(ABC) transporter
HPG92_RS03525	COG3708	Transcriptional regulator
HPG92_RS03525	COG2207	Transcriptional regulator
HPG92_RS03530	COG3045	CreA protein
HPG92_RS03550	COG3121	Chaperone
HPG92_RS03570	COG0745	RESPONSE REGULATOR receiver
HPG92_RS03580	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
HPG92_RS03590	COG0527	aspartate kinase activity
HPG92_RS03590	COG0460	homoserine dehydrogenase
HPG92_RS03600	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HPG92_RS03610	COG1115	amino acid carrier protein
HPG92_RS03620	COG0521	Mo-molybdopterin cofactor biosynthetic process
HPG92_RS03625	COG1584	GPR1 FUN34 yaaH family protein
HPG92_RS03630	COG4735	regulation of single-species biofilm formation
HPG92_RS03680	COG0737	Belongs to the 5'-nucleotidase family
HPG92_RS03690	COG3119	arylsulfatase activity
HPG92_RS03695	COG0641	radical SAM
HPG92_RS03715	COG0583	DNA-binding transcription factor activity
HPG92_RS03730	COG0196	riboflavin kinase activity
HPG92_RS03745	COG1047	Peptidyl-prolyl cis-trans
HPG92_RS03835	COG0644	oxidoreductase
HPG92_RS03845	COG2271	Major facilitator Superfamily
HPG92_RS03865	COG3119	arylsulfatase activity
HPG92_RS03910	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HPG92_RS03930	COG0417	DNA replication proofreading
HPG92_RS03970	COG0586	Pfam SNARE associated Golgi protein
HPG92_RS04000	COG2814	Major facilitator Superfamily
HPG92_RS04065	COG0768	penicillin binding
HPG92_RS04075	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HPG92_RS04090	COG0772	Belongs to the SEDS family
HPG92_RS04115	COG0849	cell division
HPG92_RS04120	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HPG92_RS04145	COG0494	nUDIX hydrolase
HPG92_RS04175	COG1459	type II secretion system
HPG92_RS04180	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HPG92_RS04185	COG4969	Belongs to the N-Me-Phe pilin family
HPG92_RS04200	COG3725	Membrane protein required for beta-lactamase induction
HPG92_RS04205	COG3940	Belongs to the glycosyl hydrolase 43 family
HPG92_RS04210	COG2211	Major facilitator Superfamily
HPG92_RS04225	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HPG92_RS04230	COG0508	dehydrogenase complex catalyzes the overall conversion of
HPG92_RS04235	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HPG92_RS04250	COG3064	Membrane
HPG92_RS04280	COG1349	DNA-binding transcription factor activity
HPG92_RS04300	COG2132	Multicopper oxidase
HPG92_RS04305	COG4993	Dehydrogenase
HPG92_RS04315	COG0288	reversible hydration of carbon dioxide
HPG92_RS04320	COG1131	(ABC) transporter
HPG92_RS04325	COG0842	Transport permease protein
HPG92_RS04330	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HPG92_RS04335	COG0726	polysaccharide deacetylase
HPG92_RS04355	COG3539	Fimbrial protein
HPG92_RS04360	COG3188	usher protein
HPG92_RS04365	COG3121	Chaperone
HPG92_RS04390	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HPG92_RS04395	COG0617	tRNA 3'-terminal CCA addition
HPG92_RS04410	COG1489	DNA binding
HPG92_RS04415	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HPG92_RS04420	COG1643	Atp-dependent helicase
HPG92_RS04425	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HPG92_RS04430	COG4774	siderophore transport
HPG92_RS04435	COG1120	ATPase activity
HPG92_RS04440	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HPG92_RS04465	COG2860	membrane
HPG92_RS04470	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HPG92_RS04500	COG0477	Major facilitator Superfamily
HPG92_RS04550	COG0575	Belongs to the CDS family
HPG92_RS04615	COG0346	lactoylglutathione lyase activity
HPG92_RS04625	COG4568	rho-dependent transcription termination
HPG92_RS04640	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HPG92_RS04645	COG3015	lipoprotein NlpE involved in copper resistance
HPG92_RS04655	COG1720	tRNA m6t6A37 methyltransferase activity
HPG92_RS04680	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HPG92_RS04720	COG0583	DNA-binding transcription factor activity
HPG92_RS04725	COG2814	Major facilitator Superfamily
HPG92_RS04740	COG0741	lytic transglycosylase activity
HPG92_RS04740	COG1388	LysM domain
HPG92_RS04750	COG2226	methyltransferase
HPG92_RS04785	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HPG92_RS04800	COG0121	glutamine amidotransferase
HPG92_RS04805	COG3034	peptidoglycan biosynthetic process
HPG92_RS04815	COG2195	Cleaves the N-terminal amino acid of tripeptides
HPG92_RS04880	COG0402	S-adenosylhomocysteine deaminase activity
HPG92_RS04895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HPG92_RS04900	COG2217	Heavy metal translocating P-type atpase
HPG92_RS04905	COG0789	Transcriptional regulator
HPG92_RS04915	COG2814	Major facilitator Superfamily
HPG92_RS04935	COG1271	oxidase subunit
HPG92_RS04940	COG1294	oxidase, subunit
HPG92_RS04960	COG1280	lysine exporter protein (LysE YggA)
HPG92_RS04995	COG0113	porphobilinogen synthase activity
HPG92_RS05010	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HPG92_RS05015	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
HPG92_RS05060	COG3706	GGDEF domain
HPG92_RS05065	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HPG92_RS05085	COG4126	flavin adenine dinucleotide binding
HPG92_RS05100	COG1940	carbohydrate kinase activity
HPG92_RS05105	COG2814	Major facilitator Superfamily
HPG92_RS05110	COG0419	ATPase involved in DNA repair
HPG92_RS05115	COG0420	3'-5' exonuclease activity
HPG92_RS05125	COG5002	protein histidine kinase activity
HPG92_RS05140	COG0366	Alpha amylase catalytic
HPG92_RS05150	COG0450	alkyl hydroperoxide reductase
HPG92_RS05170	COG1862	Preprotein translocase
HPG92_RS05180	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HPG92_RS05200	COG4238	major outer membrane lipoprotein
HPG92_RS05210	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HPG92_RS05210	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HPG92_RS05230	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HPG92_RS05235	COG0667	Aldo Keto reductase
HPG92_RS05245	COG0142	geranyltranstransferase activity
HPG92_RS05275	COG2814	Major facilitator Superfamily
HPG92_RS05285	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HPG92_RS05290	COG1845	cytochrome c oxidase, subunit III
HPG92_RS05295	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HPG92_RS05300	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HPG92_RS05305	COG2223	nitrite transmembrane transporter activity
HPG92_RS05310	COG3056	Lipoprotein
HPG92_RS05315	COG0271	Belongs to the BolA IbaG family
HPG92_RS05340	COG0776	regulation of translation
HPG92_RS05345	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HPG92_RS05350	COG1555	photosystem II stabilization
HPG92_RS05355	COG0824	Thioesterase
HPG92_RS05365	COG4533	DNA binding
HPG92_RS05370	COG0561	phosphatase activity
HPG92_RS05385	COG1522	sequence-specific DNA binding
HPG92_RS05390	COG1132	(ABC) transporter
HPG92_RS05395	COG1132	(ABC) transporter
HPG92_RS05400	COG0347	Belongs to the P(II) protein family
HPG92_RS05405	COG0004	ammonium transporteR
HPG92_RS05410	COG1946	Acyl-CoA thioesterase
HPG92_RS05415	COG3126	Type III secretion system lipoprotein chaperone (YscW)
HPG92_RS05420	COG3695	enzyme binding
HPG92_RS05430	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HPG92_RS05450	COG0110	maltose O-acetyltransferase activity
HPG92_RS05465	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HPG92_RS05470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HPG92_RS05475	COG1309	transcriptional regulator
HPG92_RS05480	COG3264	Mechanosensitive ion channel
HPG92_RS05480	COG1196	nuclear chromosome segregation
HPG92_RS05490	COG4974	Belongs to the 'phage' integrase family
HPG92_RS05495	COG0582	viral genome integration into host DNA
HPG92_RS05500	COG4974	Belongs to the 'phage' integrase family
HPG92_RS05520	COG3923	Primosomal replication protein n
HPG92_RS05525	COG2832	Protein of unknown function (DUF454)
HPG92_RS05570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HPG92_RS05575	COG4651	solute:proton antiporter activity
HPG92_RS05575	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HPG92_RS05580	COG2223	nitrite transmembrane transporter activity
HPG92_RS05595	COG3735	TraB family
HPG92_RS05600	COG2217	Heavy metal translocating P-type atpase
HPG92_RS05610	COG1585	Membrane protein implicated in regulation of membrane protease activity
HPG92_RS05615	COG0330	HflC and HflK could
HPG92_RS05620	COG4619	ABC transporter
HPG92_RS05625	COG0390	transport system, permease component
HPG92_RS05630	COG3118	belongs to the thioredoxin family
HPG92_RS05635	COG0300	oxidoreductase activity
HPG92_RS05640	COG2755	lipolytic protein G-D-S-L family
HPG92_RS05645	COG4181	ATPase activity
HPG92_RS05650	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HPG92_RS05660	COG1464	Belongs to the NlpA lipoprotein family
HPG92_RS05680	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HPG92_RS05685	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HPG92_RS05695	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HPG92_RS05705	COG2501	S4 domain
HPG92_RS05790	COG2207	Transcriptional regulator
HPG92_RS05795	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HPG92_RS05805	COG3059	membrane
HPG92_RS05815	COG1113	amino acid transport
HPG92_RS05820	COG0668	transmembrane transport
HPG92_RS05830	COG2723	6-phospho-beta-galactosidase activity
HPG92_RS05840	COG1447	Phosphotransferase system cellobiose-specific component IIA
HPG92_RS05845	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HPG92_RS05855	COG2188	Transcriptional regulator
HPG92_RS05865	COG2315	Protein conserved in bacteria
HPG92_RS05895	COG4771	TonB-dependent receptor
HPG92_RS05900	COG2382	esterase
HPG92_RS05905	COG3251	PFAM MbtH domain protein
HPG92_RS05910	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HPG92_RS05910	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HPG92_RS05915	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
HPG92_RS05920	COG1120	ATPase activity
HPG92_RS05925	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HPG92_RS05930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HPG92_RS05940	COG4592	Periplasmic binding protein
HPG92_RS05945	COG1169	isochorismate synthase
HPG92_RS05950	COG1021	2,3-dihydroxybenzoate-AMP ligase
HPG92_RS05955	COG3433	isochorismatase activity
HPG92_RS05955	COG1535	isochorismatase
HPG92_RS05960	COG1028	Short-chain dehydrogenase reductase Sdr
HPG92_RS05970	COG1966	Carbon starvation protein
HPG92_RS05975	COG2879	small protein
HPG92_RS05980	COG0371	Dehydrogenase
HPG92_RS05985	COG0436	Aminotransferase
HPG92_RS05990	COG1475	DNA binding
HPG92_RS05995	COG3969	phosphoadenosine phosphosulfate
HPG92_RS06000	COG0583	DNA-binding transcription factor activity
HPG92_RS06005	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HPG92_RS06025	COG1063	alcohol dehydrogenase
HPG92_RS06030	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HPG92_RS06035	COG3719	Belongs to the RNase T2 family
HPG92_RS06040	COG0471	metal ion transport
HPG92_RS06055	COG3051	citrate lyase alpha subunit
HPG92_RS06060	COG2301	Belongs to the HpcH HpaI aldolase family
HPG92_RS06070	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HPG92_RS06075	COG3290	protein histidine kinase activity
HPG92_RS06080	COG4565	transcriptional regulatory protein
HPG92_RS06085	COG3069	C4-dicarboxylate transmembrane transporter activity
HPG92_RS06105	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HPG92_RS06120	COG0583	DNA-binding transcription factor activity
HPG92_RS06135	COG1686	Belongs to the peptidase S11 family
HPG92_RS06145	COG0772	Belongs to the SEDS family
HPG92_RS06150	COG0768	penicillin binding
HPG92_RS06160	COG0799	negative regulation of ribosome biogenesis
HPG92_RS06175	COG1466	dna polymerase III delta subunit
HPG92_RS06190	COG2888	peptidyl-tyrosine sulfation
HPG92_RS06200	COG1126	abc transporter atp-binding protein
HPG92_RS06205	COG0765	amino acid transport
HPG92_RS06210	COG0765	amino acid transport
HPG92_RS06235	COG1702	phosphate starvation-inducible protein PhoH
HPG92_RS06245	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HPG92_RS06285	COG0367	asparagine synthase
HPG92_RS06290	COG0647	UMP catabolic process
HPG92_RS06295	COG1940	carbohydrate kinase activity
HPG92_RS06295	COG1846	Transcriptional regulator
HPG92_RS06300	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HPG92_RS06340	COG1053	succinate dehydrogenase
HPG92_RS06345	COG0583	DNA-binding transcription factor activity
HPG92_RS06350	COG0735	belongs to the Fur family
HPG92_RS06365	COG0596	Alpha beta hydrolase
HPG92_RS06375	COG0033	Phosphoglucomutase
HPG92_RS06385	COG0531	amino acid
HPG92_RS06390	COG1982	Orn Lys Arg decarboxylase major
HPG92_RS06400	COG0745	RESPONSE REGULATOR receiver
HPG92_RS06405	COG2205	protein histidine kinase activity
HPG92_RS06465	COG2801	Transposase and inactivated derivatives
HPG92_RS06470	COG2842	Transposition protein
HPG92_RS06545	COG5566	PFAM Mor transcription activator
HPG92_RS06590	COG4373	Mu-like prophage FluMu protein gp28
HPG92_RS06595	COG4383	Mu-like prophage protein gp29
HPG92_RS06600	COG2369	cell adhesion
HPG92_RS06610	COG5005	Phage virion morphogenesis
HPG92_RS06620	COG4397	Mu-like prophage major head subunit gpT
HPG92_RS06635	COG5003	unkown
HPG92_RS06645	COG4386	tail sheath protein
HPG92_RS06655	COG4518	Phage tail assembly chaperone proteins, E, or 41 or 14
HPG92_RS06665	COG4228	DNA circulation
HPG92_RS06675	COG4384	Bacteriophage Mu Gp45 protein
HPG92_RS06685	COG3299	homolog of phage Mu protein gp47
HPG92_RS06695	COG5301	cellulose 1,4-beta-cellobiosidase activity
HPG92_RS06735	COG0270	DNA (cytosine-5-)-methyltransferase activity
HPG92_RS06750	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HPG92_RS06790	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HPG92_RS06805	COG0567	Dehydrogenase, E1 component
HPG92_RS06810	COG0508	dehydrogenase complex catalyzes the overall conversion of
HPG92_RS06820	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HPG92_RS06830	COG0583	DNA-binding transcription factor activity
HPG92_RS06840	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HPG92_RS06840	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HPG92_RS06865	COG3799	methylaspartate ammonia-lyase activity
HPG92_RS06870	COG4865	methylaspartate mutase activity
HPG92_RS06880	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HPG92_RS06885	COG1271	oxidase subunit
HPG92_RS06890	COG1294	oxidase, subunit
HPG92_RS06895	COG4890	Cyd operon protein YbgT
HPG92_RS06900	COG3790	cyd operon protein YbgE
HPG92_RS06905	COG0824	Thioesterase
HPG92_RS06910	COG0811	peptide transport
HPG92_RS06915	COG0848	biopolymer transport protein
HPG92_RS06920	COG3064	Membrane
HPG92_RS06930	COG2885	chlorophyll binding
HPG92_RS06935	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HPG92_RS06995	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HPG92_RS07000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HPG92_RS07005	COG1120	ATPase activity
HPG92_RS07020	COG0183	Belongs to the thiolase family
HPG92_RS07025	COG1028	Short-chain dehydrogenase reductase Sdr
HPG92_RS07040	COG2017	converts alpha-aldose to the beta-anomer
HPG92_RS07060	COG1119	ATPase activity
HPG92_RS07065	COG2005	Transcriptional regulator
HPG92_RS07065	COG3585	molybdate ion transport
HPG92_RS07075	COG0725	ABC transporter, periplasmic molybdate-binding protein
HPG92_RS07080	COG4149	molybdate abc transporter
HPG92_RS07090	COG0561	phosphatase activity
HPG92_RS07105	COG4677	pectinesterase activity
HPG92_RS07135	COG1881	PFAM PEBP family protein
HPG92_RS07180	COG0521	Mo-molybdopterin cofactor biosynthetic process
HPG92_RS07190	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HPG92_RS07200	COG0670	Belongs to the BI1 family
HPG92_RS07205	COG0392	lysyltransferase activity
HPG92_RS07210	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HPG92_RS07215	COG3568	Endonuclease Exonuclease Phosphatase
HPG92_RS07225	COG0842	Transport permease protein
HPG92_RS07230	COG0842	Transport permease protein
HPG92_RS07235	COG1131	(ABC) transporter
HPG92_RS07245	COG1309	transcriptional regulator
HPG92_RS07260	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HPG92_RS07270	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HPG92_RS07280	COG0668	transmembrane transport
HPG92_RS07285	COG1126	abc transporter atp-binding protein
HPG92_RS07290	COG0765	amino acid transport
HPG92_RS07295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HPG92_RS07310	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HPG92_RS07315	COG2194	sulfuric ester hydrolase activity
HPG92_RS07330	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HPG92_RS07335	COG1376	ErfK ybiS ycfS ynhG family protein
HPG92_RS07340	COG0488	(ABC) transporter
HPG92_RS07350	COG0561	phosphatase activity
HPG92_RS07355	COG1882	Formate acetyltransferase
HPG92_RS07360	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HPG92_RS07385	COG0747	negative chemotaxis
HPG92_RS07410	COG2133	pyrroloquinoline quinone binding
HPG92_RS07420	COG1686	Belongs to the peptidase S11 family
HPG92_RS07425	COG1349	DNA-binding transcription factor activity
HPG92_RS07430	COG0671	phosphoesterase, PA-phosphatase related
HPG92_RS07435	COG2814	Major facilitator Superfamily
HPG92_RS07440	COG0561	phosphatase activity
HPG92_RS07445	COG0738	Major facilitator superfamily
HPG92_RS07450	COG3226	Transcriptional regulator
HPG92_RS07490	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HPG92_RS07495	COG3842	ATPase activity
HPG92_RS07500	COG1176	ABC-type spermidine putrescine transport system, permease component I
HPG92_RS07505	COG1177	transmembrane transport
HPG92_RS07535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HPG92_RS07540	COG4160	amino acid transport
HPG92_RS07545	COG4215	(ABC) transporter
HPG92_RS07550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HPG92_RS07555	COG1126	abc transporter atp-binding protein
HPG92_RS07620	COG3023	N-Acetylmuramoyl-L-alanine amidase
HPG92_RS07625	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HPG92_RS07630	COG0702	epimerase
HPG92_RS07635	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
HPG92_RS07640	COG0028	Belongs to the TPP enzyme family
HPG92_RS07645	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HPG92_RS07655	COG2431	L-lysine efflux transmembrane transporter activity
HPG92_RS07660	COG3593	DNA synthesis involved in DNA repair
HPG92_RS07665	COG2990	Protein conserved in bacteria
HPG92_RS07670	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HPG92_RS07675	COG1136	(ABC) transporter
HPG92_RS07675	COG0577	efflux transmembrane transporter activity
HPG92_RS07680	COG1278	Cold shock
HPG92_RS07690	COG0542	response to heat
HPG92_RS07700	COG1335	isochorismatase
HPG92_RS07710	COG0583	DNA-binding transcription factor activity
HPG92_RS07730	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HPG92_RS07735	COG4988	ABC transporter
HPG92_RS07740	COG0492	ferredoxin-NADP+ reductase activity
HPG92_RS07760	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HPG92_RS07770	COG0243	molybdopterin cofactor binding
HPG92_RS07775	COG0437	4 iron, 4 sulfur cluster binding
HPG92_RS07780	COG3302	dmso reductase anchor subunit
HPG92_RS07785	COG1335	isochorismatase
HPG92_RS07795	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HPG92_RS07805	COG1882	Formate acetyltransferase
HPG92_RS07810	COG2116	formate transmembrane transporter activity
HPG92_RS07815	COG1944	ATP diphosphatase activity
HPG92_RS07820	COG2323	membrane
HPG92_RS07835	COG0501	Belongs to the peptidase M48B family
HPG92_RS07845	COG0539	negative regulation of cytoplasmic translation
HPG92_RS07855	COG2333	competence protein COMEC
HPG92_RS07855	COG0658	competence protein
HPG92_RS07870	COG3214	Protein conserved in bacteria
HPG92_RS07885	COG3173	Aminoglycoside phosphotransferase
HPG92_RS07890	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HPG92_RS07895	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HPG92_RS07905	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
HPG92_RS07915	COG2989	Protein conserved in bacteria
HPG92_RS07920	COG3108	Peptidase M15
HPG92_RS07925	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HPG92_RS07940	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HPG92_RS07955	COG0308	aminopeptidase N
HPG92_RS07970	COG3217	Mosc domain protein beta barrel domain protein
HPG92_RS07970	COG0633	Ferredoxin
HPG92_RS07980	COG0488	(ABC) transporter
HPG92_RS07985	COG2995	paraquat-inducible protein a
HPG92_RS07990	COG3008	intermembrane lipid transfer
HPG92_RS07990	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HPG92_RS07995	COG3009	Protein conserved in bacteria
HPG92_RS08000	COG3130	regulation of translation
HPG92_RS08010	COG1067	ATP-dependent peptidase activity
HPG92_RS08030	COG3070	regulator of competence-specific genes
HPG92_RS08035	COG1289	transmembrane transporter activity
HPG92_RS08040	COG3304	Inner membrane component domain
HPG92_RS08045	COG0210	DNA helicase
HPG92_RS08060	COG1832	CoA-binding protein
HPG92_RS08095	COG0670	Belongs to the BI1 family
HPG92_RS08140	COG0076	glutamate decarboxylase activity
HPG92_RS08205	COG2205	protein histidine kinase activity
HPG92_RS08210	COG0745	RESPONSE REGULATOR receiver
HPG92_RS08230	COG1846	Transcriptional regulator
HPG92_RS08240	COG1012	belongs to the aldehyde dehydrogenase family
HPG92_RS08245	COG3384	dioxygenase
HPG92_RS08255	COG3971	2-oxopent-4-enoate hydratase activity
HPG92_RS08300	COG4232	protein-disulfide reductase activity
HPG92_RS08305	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HPG92_RS08305	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HPG92_RS08310	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HPG92_RS08330	COG3729	General stress protein
HPG92_RS08335	COG1309	transcriptional regulator
HPG92_RS08355	COG1702	phosphate starvation-inducible protein PhoH
HPG92_RS08360	COG1737	Transcriptional regulator
HPG92_RS08365	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HPG92_RS08390	COG2814	Major facilitator Superfamily
HPG92_RS08395	COG0673	inositol 2-dehydrogenase activity
HPG92_RS08415	COG3381	protein complex oligomerization
HPG92_RS08470	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HPG92_RS08485	COG2943	transferase activity, transferring hexosyl groups
HPG92_RS08490	COG5645	(Lipo)protein
HPG92_RS08520	COG3038	cytochrome b561
HPG92_RS08555	COG2999	glutathione oxidoreductase activity
HPG92_RS08565	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HPG92_RS08655	COG1530	ribonuclease E activity
HPG92_RS08660	COG0564	pseudouridine synthase activity
HPG92_RS08705	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HPG92_RS08710	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HPG92_RS08715	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HPG92_RS08725	COG0470	DNA polymerase III
HPG92_RS08730	COG0084	hydrolase, TatD family'
HPG92_RS08740	COG0537	adenosine 5'-monophosphoramidase activity
HPG92_RS08745	COG5633	Lipoprotein
HPG92_RS08775	COG3134	Outer membrane lipoprotein
HPG92_RS08780	COG1309	transcriptional regulator
HPG92_RS08795	COG1388	LysM domain
HPG92_RS08795	COG1376	ErfK ybiS ycfS ynhG family protein
HPG92_RS08800	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HPG92_RS08805	COG4591	ABC-type transport system involved in lipoprotein release permease component
HPG92_RS08810	COG1136	(ABC) transporter
HPG92_RS08815	COG4591	ABC-type transport system involved in lipoprotein release permease component
HPG92_RS08835	COG1177	transmembrane transport
HPG92_RS08860	COG2850	peptidyl-arginine hydroxylation
HPG92_RS08875	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HPG92_RS08905	COG0538	isocitrate dehydrogenase activity
HPG92_RS08935	COG3179	chitinase
HPG92_RS09060	COG0071	Belongs to the small heat shock protein (HSP20) family
HPG92_RS09070	COG3038	cytochrome b561
HPG92_RS09080	COG0747	negative chemotaxis
HPG92_RS09100	COG1124	(ABC) transporter
HPG92_RS09105	COG0668	transmembrane transport
HPG92_RS09120	COG3443	Belongs to the bacterial solute-binding protein 9 family
HPG92_RS09135	COG0789	Transcriptional regulator
HPG92_RS09145	COG1605	Chorismate mutase
HPG92_RS09155	COG3615	Tellurite resistance protein tehB
HPG92_RS09170	COG2261	transglycosylase associated protein
HPG92_RS09180	COG3042	response to heat
HPG92_RS09190	COG3189	MarR family transcriptional regulator
HPG92_RS09195	COG2807	transmembrane transport
HPG92_RS09200	COG2207	Transcriptional regulator
HPG92_RS09215	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HPG92_RS09220	COG2199	diguanylate cyclase activity
HPG92_RS09235	COG2766	serine protein kinase
HPG92_RS09240	COG3713	MltA-interacting MipA family protein
HPG92_RS09245	COG0641	radical SAM
HPG92_RS09270	COG3139	Protein of unknown function (DUF1315)
HPG92_RS09275	COG1335	isochorismatase
HPG92_RS09280	COG0252	asparaginase activity
HPG92_RS09285	COG0616	signal peptide processing
HPG92_RS09290	COG0778	Nitroreductase
HPG92_RS09300	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HPG92_RS09315	COG0494	nUDIX hydrolase
HPG92_RS09350	COG3678	ATP-independent chaperone mediated protein folding
HPG92_RS09355	COG0322	excinuclease ABC activity
HPG92_RS09365	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HPG92_RS09370	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HPG92_RS09375	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HPG92_RS09380	COG1447	Phosphotransferase system cellobiose-specific component IIA
HPG92_RS09385	COG2169	Transcriptional regulator
HPG92_RS09385	COG1917	Cupin 2, conserved barrel domain protein
HPG92_RS09390	COG1486	melibiose metabolic process
HPG92_RS09400	COG0753	catalase activity
HPG92_RS09415	COG1988	membrane-bound metal-dependent
HPG92_RS09420	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HPG92_RS09430	COG3001	Fructosamine kinase
HPG92_RS09440	COG1105	Belongs to the carbohydrate kinase PfkB family
HPG92_RS09445	COG3137	Salt-induced outer membrane protein
HPG92_RS09495	COG0012	GTP binding
HPG92_RS09510	COG0659	secondary active sulfate transmembrane transporter activity
HPG92_RS09565	COG0387	Pfam Sodium calcium exchanger
HPG92_RS09570	COG4572	Cation transport regulator
HPG92_RS09575	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HPG92_RS09580	COG4932	domain protein
HPG92_RS09585	COG2197	response regulator
HPG92_RS09595	COG2223	nitrite transmembrane transporter activity
HPG92_RS09600	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HPG92_RS09605	COG1140	nitrate reductase beta subunit
HPG92_RS09610	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HPG92_RS09615	COG2181	nitrate reductase activity
HPG92_RS09650	COG0788	formyltetrahydrofolate deformylase activity
HPG92_RS09660	COG1752	Esterase of the alpha-beta hydrolase superfamily
HPG92_RS09665	COG0745	RESPONSE REGULATOR receiver
HPG92_RS09670	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HPG92_RS09685	COG1012	belongs to the aldehyde dehydrogenase family
HPG92_RS09685	COG1454	alcohol dehydrogenase
HPG92_RS09690	COG2095	MarC family integral membrane protein
HPG92_RS09720	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HPG92_RS09740	COG2350	Protein conserved in bacteria
HPG92_RS09765	COG0727	PFAM Uncharacterised protein family (UPF0153)
HPG92_RS09770	COG3047	cAMP biosynthetic process
HPG92_RS09775	COG3546	catalase activity
HPG92_RS09780	COG3685	Protein conserved in bacteria
HPG92_RS09785	COG3685	Protein conserved in bacteria
HPG92_RS09790	COG3729	General stress protein
HPG92_RS09830	COG0009	L-threonylcarbamoyladenylate synthase
HPG92_RS09845	COG1028	Short-chain dehydrogenase reductase Sdr
HPG92_RS09850	COG0616	signal peptide processing
HPG92_RS09890	COG0671	phosphoesterase, PA-phosphatase related
HPG92_RS09895	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
HPG92_RS09900	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HPG92_RS09920	COG1349	DNA-binding transcription factor activity
HPG92_RS09930	COG5001	Diguanylate cyclase
HPG92_RS10045	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HPG92_RS10050	COG1842	Phage shock protein A
HPG92_RS10060	COG1983	PspC domain protein
HPG92_RS10070	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HPG92_RS10075	COG3106	COG3106 Predicted ATPase
HPG92_RS10105	COG2814	Major facilitator Superfamily
HPG92_RS10125	COG4948	Mandelate Racemase Muconate Lactonizing
HPG92_RS10130	COG2866	Carboxypeptidase
HPG92_RS10135	COG4166	transmembrane transport
HPG92_RS10145	COG0582	viral genome integration into host DNA
HPG92_RS10160	COG0582	viral genome integration into host DNA
HPG92_RS10165	COG3539	Fimbrial protein
HPG92_RS10170	COG3121	Chaperone
HPG92_RS10205	COG2808	Putative FMN-binding domain
HPG92_RS10225	COG1509	lysine 2,3-aminomutase activity
HPG92_RS10235	COG1113	amino acid transport
HPG92_RS10240	COG0673	inositol 2-dehydrogenase activity
HPG92_RS10265	COG3842	ATPase activity
HPG92_RS10280	COG0395	ABC-type sugar transport system, permease component
HPG92_RS10285	COG4209	transmembrane transport
HPG92_RS10290	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HPG92_RS10295	COG1028	Short-chain dehydrogenase reductase Sdr
HPG92_RS10300	COG1309	transcriptional regulator
HPG92_RS10330	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HPG92_RS10350	COG0668	transmembrane transport
HPG92_RS10355	COG3182	Iron-regulated membrane protein
HPG92_RS10375	COG2840	Smr protein MutS2
HPG92_RS10395	COG0513	Belongs to the DEAD box helicase family
HPG92_RS10415	COG2076	Multidrug Resistance protein
HPG92_RS10425	COG0674	pyruvate-flavodoxin oxidoreductase activity
HPG92_RS10425	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HPG92_RS10425	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HPG92_RS10425	COG1013	pyruvate-flavodoxin oxidoreductase activity
HPG92_RS10435	COG3042	response to heat
HPG92_RS10440	COG3187	Heat shock protein
HPG92_RS10445	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HPG92_RS10450	COG2911	Protein conserved in bacteria
HPG92_RS10460	COG3784	Protein of unknown function (DUF1318)
HPG92_RS10475	COG1643	Atp-dependent helicase
HPG92_RS10480	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HPG92_RS10485	COG3038	cytochrome b561
HPG92_RS10490	COG0500	methyltransferase
HPG92_RS10530	COG0583	DNA-binding transcription factor activity
HPG92_RS10535	COG5383	Protein conserved in bacteria
HPG92_RS10545	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
HPG92_RS10550	COG2353	YceI-like domain
HPG92_RS10555	COG1304	FMN binding
HPG92_RS10565	COG1349	DNA-binding transcription factor activity
HPG92_RS10650	COG1473	amidohydrolase
HPG92_RS10655	COG2860	membrane
HPG92_RS10670	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HPG92_RS10675	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HPG92_RS10680	COG1275	C4-dicarboxylate transporter malic acid transport protein
HPG92_RS10685	COG0500	methyltransferase
HPG92_RS10725	COG1396	sequence-specific DNA binding
HPG92_RS10730	COG0826	peptidase U32
HPG92_RS10745	COG1294	oxidase, subunit
HPG92_RS10765	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HPG92_RS10770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HPG92_RS10820	COG2130	NADP-dependent
HPG92_RS10825	COG1802	Transcriptional regulator
HPG92_RS10830	COG4772	TonB-dependent receptor
HPG92_RS10895	COG0437	4 iron, 4 sulfur cluster binding
HPG92_RS10900	COG2864	formate dehydrogenase
HPG92_RS10925	COG1764	response to oxidative stress
HPG92_RS10940	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HPG92_RS10955	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HPG92_RS10985	COG1484	DNA-dependent DNA replication
HPG92_RS10990	COG4584	PFAM Integrase catalytic
HPG92_RS11075	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HPG92_RS11100	COG2271	Major facilitator Superfamily
HPG92_RS11105	COG1063	alcohol dehydrogenase
HPG92_RS11110	COG2186	Transcriptional regulator
HPG92_RS11120	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
HPG92_RS11125	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
HPG92_RS11150	COG1773	rubredoxin
HPG92_RS11185	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HPG92_RS11200	COG3781	membrane
HPG92_RS11220	COG1012	belongs to the aldehyde dehydrogenase family
HPG92_RS11225	COG0583	DNA-binding transcription factor activity
HPG92_RS11255	COG4566	intracellular signal transduction
HPG92_RS11270	COG2814	Major facilitator Superfamily
HPG92_RS11280	COG3111	PFAM Bacterial OB fold (BOF) protein
HPG92_RS11285	COG1546	Belongs to the CinA family
HPG92_RS11290	COG3729	General stress protein
HPG92_RS11300	COG4221	oxidoreductase activity
HPG92_RS11305	COG1802	Transcriptional regulator
HPG92_RS11315	COG0246	Mannitol dehydrogenase
HPG92_RS11320	COG0477	Major facilitator Superfamily
HPG92_RS11325	COG1063	alcohol dehydrogenase
HPG92_RS11345	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HPG92_RS11360	COG0243	molybdopterin cofactor binding
HPG92_RS11365	COG0243	molybdopterin cofactor binding
HPG92_RS11370	COG0437	4 iron, 4 sulfur cluster binding
HPG92_RS11375	COG3302	dmso reductase anchor subunit
HPG92_RS11415	COG1940	carbohydrate kinase activity
HPG92_RS11420	COG0583	DNA-binding transcription factor activity
HPG92_RS11425	COG2814	Major facilitator Superfamily
HPG92_RS11435	COG3591	Belongs to the peptidase S1B family
HPG92_RS11450	COG0628	permease
HPG92_RS11455	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HPG92_RS11460	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HPG92_RS11470	COG0531	amino acid
HPG92_RS11475	COG3136	membrane protein required for alginate biosynthesis
HPG92_RS11480	COG0745	RESPONSE REGULATOR receiver
HPG92_RS11485	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HPG92_RS11495	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HPG92_RS11500	COG2205	protein histidine kinase activity
HPG92_RS11525	COG5339	Protein conserved in bacteria
HPG92_RS11530	COG1609	Transcriptional regulator
HPG92_RS11535	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HPG92_RS11535	COG1263	PTS System
HPG92_RS11540	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HPG92_RS11550	COG0673	inositol 2-dehydrogenase activity
HPG92_RS11590	COG4659	FMN binding
HPG92_RS11600	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HPG92_RS11610	COG0625	glutathione transferase activity
HPG92_RS11630	COG3895	Periplasmic Protein
HPG92_RS11655	COG1566	PFAM secretion protein HlyD family protein
HPG92_RS11670	COG4989	oxidoreductase activity
HPG92_RS11675	COG3313	Fe-S protein
HPG92_RS11680	COG1309	transcriptional regulator
HPG92_RS11685	COG1902	pentaerythritol trinitrate reductase activity
HPG92_RS11700	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HPG92_RS11705	COG0791	NLP P60 protein
HPG92_RS11725	COG0583	DNA-binding transcription factor activity
HPG92_RS11730	COG2814	Major facilitator Superfamily
HPG92_RS11735	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HPG92_RS11740	COG0307	riboflavin synthase, alpha
HPG92_RS11910	COG2205	protein histidine kinase activity
HPG92_RS11910	COG0784	Response regulator, receiver
HPG92_RS11910	COG2198	Histidine kinase
HPG92_RS11920	COG0789	Transcriptional regulator
HPG92_RS11925	COG3272	Protein of unknown function (DUF1722)
HPG92_RS11960	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HPG92_RS11970	COG2267	carboxylic ester hydrolase activity
HPG92_RS11975	COG0531	amino acid
HPG92_RS11990	COG1376	ErfK ybiS ycfS ynhG family protein
HPG92_RS12005	COG0719	Fe-S assembly protein
HPG92_RS12010	COG0396	ATPase activity
HPG92_RS12015	COG0719	Fe-S assembly protein
HPG92_RS12020	COG0316	Belongs to the HesB IscA family
HPG92_RS12035	COG2050	protein possibly involved in aromatic compounds catabolism
HPG92_RS12040	COG0247	lactate metabolic process
HPG92_RS12040	COG0277	FAD linked oxidase domain protein
HPG92_RS12045	COG0628	permease
HPG92_RS12055	COG0710	3-dehydroquinate dehydratase activity
HPG92_RS12060	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HPG92_RS12060	COG0574	Belongs to the PEP-utilizing enzyme family
HPG92_RS12075	COG4256	Hemin uptake protein
HPG92_RS12090	COG0791	NLP P60 protein
HPG92_RS12100	COG0386	Belongs to the glutathione peroxidase family
HPG92_RS12190	COG3119	arylsulfatase activity
HPG92_RS12195	COG0641	radical SAM
HPG92_RS12210	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HPG92_RS12215	COG3716	PTS system mannose fructose sorbose family IID component
HPG92_RS12220	COG3715	PTS system
HPG92_RS12225	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HPG92_RS12230	COG1349	DNA-binding transcription factor activity
HPG92_RS12235	COG3119	arylsulfatase activity
HPG92_RS12245	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
HPG92_RS12255	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
HPG92_RS12260	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HPG92_RS12265	COG1999	signal sequence binding
HPG92_RS12270	COG1773	rubredoxin
HPG92_RS12275	COG1271	oxidase subunit
HPG92_RS12280	COG1294	oxidase, subunit
HPG92_RS12290	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HPG92_RS12315	COG1619	proteins homologs of microcin C7 resistance protein MccF
HPG92_RS12335	COG2719	SpoVR family
HPG92_RS12375	COG0179	Fumarylacetoacetate (FAA) hydrolase
HPG92_RS12390	COG2894	cell division
HPG92_RS12400	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
HPG92_RS12410	COG3065	identical protein binding
HPG92_RS12420	COG1199	ATP-dependent helicase activity
HPG92_RS12425	COG0251	oxidation-reduction process
HPG92_RS12445	COG1760	l-serine dehydratase
HPG92_RS12450	COG2200	EAL domain
HPG92_RS12455	COG1253	flavin adenine dinucleotide binding
HPG92_RS12460	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HPG92_RS12460	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HPG92_RS12465	COG3715	PTS system
HPG92_RS12470	COG3716	PTS system mannose fructose sorbose family IID component
HPG92_RS12485	COG2226	methyltransferase
HPG92_RS12490	COG0768	penicillin binding
HPG92_RS12520	COG1414	Transcriptional regulator
HPG92_RS12525	COG2814	Major facilitator Superfamily
HPG92_RS12550	COG1956	GAF domain-containing protein
HPG92_RS12555	COG2995	paraquat-inducible protein a
HPG92_RS12560	COG3008	intermembrane lipid transfer
HPG92_RS12635	COG1276	copper resistance
HPG92_RS12640	COG2372	response to copper ion
HPG92_RS12650	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HPG92_RS12655	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HPG92_RS12660	COG1770	oligopeptidase
HPG92_RS12665	COG2979	Protein of unknown function (DUF533)
HPG92_RS12675	COG3141	response to X-ray
HPG92_RS12685	COG0800	Aldolase
HPG92_RS12690	COG0129	dihydroxy-acid dehydratase activity
HPG92_RS12695	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HPG92_RS12700	COG1737	Transcriptional regulator
HPG92_RS12715	COG1560	Kdo2-lipid A biosynthetic process
HPG92_RS12725	COG0739	heme binding
HPG92_RS12730	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HPG92_RS12740	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HPG92_RS12760	COG0217	transcriptional regulatory protein
HPG92_RS12765	COG0494	nUDIX hydrolase
HPG92_RS12775	COG1335	isochorismatase
HPG92_RS12780	COG1801	Protein of unknown function DUF72
HPG92_RS12785	COG3788	relative of glutathione S-transferase, MAPEG superfamily
HPG92_RS12795	COG0500	methyltransferase
HPG92_RS12805	COG3102	Protein conserved in bacteria
HPG92_RS12820	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
HPG92_RS12925	COG1528	Iron-storage protein
HPG92_RS12945	COG1528	Iron-storage protein
HPG92_RS12955	COG0814	amino acid
HPG92_RS13015	COG2197	response regulator
HPG92_RS13025	COG2197	response regulator
HPG92_RS13100	COG0425	Belongs to the sulfur carrier protein TusA family
HPG92_RS13205	COG5475	Uncharacterized small protein (DUF2158)
HPG92_RS13210	COG2354	Protein conserved in bacteria
HPG92_RS13215	COG0697	spore germination
HPG92_RS13220	COG3727	T/G mismatch-specific endonuclease activity
HPG92_RS13225	COG0270	DNA (cytosine-5-)-methyltransferase activity
HPG92_RS13230	COG1418	mRNA catabolic process
HPG92_RS13240	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HPG92_RS13275	COG2801	Transposase and inactivated derivatives
HPG92_RS13305	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HPG92_RS13365	COG0583	DNA-binding transcription factor activity
HPG92_RS13370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HPG92_RS13385	COG1028	Short-chain dehydrogenase reductase Sdr
HPG92_RS13390	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HPG92_RS13400	COG0582	viral genome integration into host DNA
HPG92_RS13410	COG0534	Mate efflux family protein
HPG92_RS13420	COG0582	viral genome integration into host DNA
HPG92_RS13480	COG1289	transmembrane transporter activity
HPG92_RS13530	COG5301	cellulose 1,4-beta-cellobiosidase activity
HPG92_RS13620	COG0494	nUDIX hydrolase
HPG92_RS13660	COG3179	chitinase
HPG92_RS13800	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HPG92_RS13810	COG0582	viral genome integration into host DNA
HPG92_RS13815	COG2925	Exonuclease
HPG92_RS13825	COG0531	amino acid
HPG92_RS13835	COG0583	DNA-binding transcription factor activity
HPG92_RS13840	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HPG92_RS13955	COG3475	LICD family
HPG92_RS13985	COG2327	Polysaccharide pyruvyl transferase
HPG92_RS13990	COG2244	polysaccharide biosynthetic process
HPG92_RS13995	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HPG92_RS14010	COG0297	glycogen (starch) synthase activity
HPG92_RS14020	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HPG92_RS14025	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HPG92_RS14030	COG0110	maltose O-acetyltransferase activity
HPG92_RS14035	COG1216	Glycosyl transferase, family 2
HPG92_RS14045	COG0438	transferase activity, transferring glycosyl groups
HPG92_RS14050	COG1045	serine acetyltransferase
HPG92_RS14055	COG0463	Glycosyl transferase, family 2
HPG92_RS14075	COG1253	flavin adenine dinucleotide binding
HPG92_RS14080	COG2982	Protein involved in outer membrane biogenesis
HPG92_RS14095	COG5002	protein histidine kinase activity
HPG92_RS14095	COG3447	MASE1 domain protein
HPG92_RS14095	COG5001	Diguanylate cyclase
HPG92_RS14100	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HPG92_RS14105	COG0443	Heat shock 70 kDa protein
HPG92_RS14135	COG2205	protein histidine kinase activity
HPG92_RS14140	COG0745	RESPONSE REGULATOR receiver
HPG92_RS14160	COG1830	Aldolase
HPG92_RS14165	COG2211	Major facilitator Superfamily
HPG92_RS14170	COG1397	ADP-ribosylglycohydrolase
HPG92_RS14175	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HPG92_RS14180	COG2188	Transcriptional regulator
HPG92_RS14195	COG5455	response to cobalt ion
HPG92_RS14205	COG3188	usher protein
HPG92_RS14210	COG3121	Chaperone
HPG92_RS14215	COG3539	Fimbrial protein
HPG92_RS14235	COG4808	Protein conserved in bacteria
HPG92_RS14240	COG4807	Protein conserved in bacteria
HPG92_RS14250	COG3275	phosphorelay sensor kinase activity
HPG92_RS14265	COG1174	glycine betaine transport
HPG92_RS14270	COG1125	glycine betaine transport
HPG92_RS14275	COG1174	glycine betaine transport
HPG92_RS14280	COG1732	Glycine betaine
HPG92_RS14290	COG0277	FAD linked oxidase domain protein
HPG92_RS14295	COG1686	Belongs to the peptidase S11 family
HPG92_RS14305	COG0586	Pfam SNARE associated Golgi protein
HPG92_RS14310	COG1028	Short-chain dehydrogenase reductase Sdr
HPG92_RS14315	COG1538	Outer membrane efflux protein
HPG92_RS14325	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HPG92_RS14330	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HPG92_RS14335	COG0625	glutathione transferase activity
HPG92_RS14350	COG2271	Major facilitator Superfamily
HPG92_RS14365	COG1346	cytolysis
HPG92_RS14375	COG2949	membrane
HPG92_RS14385	COG0493	'glutamate synthase
HPG92_RS14415	COG2311	Membrane
HPG92_RS14435	COG4771	TonB-dependent receptor
HPG92_RS14440	COG0833	amino acid
HPG92_RS14445	COG0583	DNA-binding transcription factor activity
HPG92_RS14450	COG2855	membrane
HPG92_RS14460	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HPG92_RS14460	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HPG92_RS14460	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HPG92_RS14465	COG1105	Belongs to the carbohydrate kinase PfkB family
HPG92_RS14500	COG0523	cobalamin synthesis protein
HPG92_RS14505	COG0671	phosphoesterase, PA-phosphatase related
HPG92_RS14510	COG0791	NLP P60 protein
HPG92_RS14515	COG2200	EAL domain
HPG92_RS14520	COG4166	transmembrane transport
HPG92_RS14525	COG4174	ABC transporter (Permease)
HPG92_RS14530	COG4239	(ABC) transporter, permease
HPG92_RS14535	COG4172	Belongs to the ABC transporter superfamily
HPG92_RS14545	COG2814	Major facilitator Superfamily
HPG92_RS14555	COG1061	Type III restriction enzyme res subunit
HPG92_RS14625	COG2197	response regulator
HPG92_RS14630	COG3088	subunit of a heme lyase
HPG92_RS14630	COG4235	cytochrome complex assembly
HPG92_RS14635	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HPG92_RS14640	COG1138	Cytochrome C-type biogenesis protein
HPG92_RS14650	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HPG92_RS14655	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HPG92_RS14660	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HPG92_RS14665	COG4133	protoheme IX ABC transporter activity
HPG92_RS14670	COG3005	denitrification pathway
HPG92_RS14675	COG3043	anaerobic respiration
HPG92_RS14680	COG0348	domain, Protein
HPG92_RS14685	COG0437	4 iron, 4 sulfur cluster binding
HPG92_RS14695	COG3062	negative regulation of establishment of protein localization
HPG92_RS14700	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
HPG92_RS14700	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HPG92_RS14710	COG4615	Cyclic peptide transporter
HPG92_RS14735	COG2198	Histidine kinase
HPG92_RS14735	COG0642	Histidine kinase
HPG92_RS14770	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HPG92_RS14775	COG2814	Major facilitator Superfamily
HPG92_RS14780	COG0583	DNA-binding transcription factor activity
HPG92_RS14785	COG0584	glycerophosphoryl diester phosphodiesterase
HPG92_RS14790	COG2271	Major facilitator Superfamily
HPG92_RS14795	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HPG92_RS14805	COG0247	lactate metabolic process
HPG92_RS14900	COG1169	isochorismate synthase
HPG92_RS14905	COG4575	ribosome binding
HPG92_RS14910	COG2153	protein acetylation
HPG92_RS14920	COG0835	chemotaxis
HPG92_RS14920	COG0784	Response regulator, receiver
HPG92_RS14930	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HPG92_RS14935	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HPG92_RS14945	COG0839	Belongs to the complex I subunit 6 family
HPG92_RS14995	COG0583	DNA-binding transcription factor activity
HPG92_RS15000	COG0436	Aminotransferase
HPG92_RS15010	COG0490	domain, Protein
HPG92_RS15010	COG0471	metal ion transport
HPG92_RS15015	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HPG92_RS15040	COG1288	antiporter activity
HPG92_RS15045	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HPG92_RS15050	COG3959	Transketolase, thiamine diphosphate binding domain
HPG92_RS15055	COG3037	sugar-specific permease SgaT UlaA
HPG92_RS15065	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HPG92_RS15070	COG1609	Transcriptional regulator
HPG92_RS15080	COG0622	Phosphoesterase
HPG92_RS15085	COG0625	glutathione transferase activity
HPG92_RS15105	COG1090	epimerase
HPG92_RS15140	COG0833	amino acid
HPG92_RS15145	COG3457	Alanine racemase
HPG92_RS15150	COG0531	amino acid
HPG92_RS15160	COG3829	transcription factor binding
HPG92_RS15165	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HPG92_RS15170	COG1286	toxin biosynthetic process
HPG92_RS15175	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
HPG92_RS15180	COG0285	dihydrofolate synthase activity
HPG92_RS15190	COG0586	Pfam SNARE associated Golgi protein
HPG92_RS15200	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HPG92_RS15225	COG3423	Transcriptional regulator
HPG92_RS15240	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HPG92_RS15255	COG3101	peptidyl-lysine hydroxylation
HPG92_RS15260	COG0730	response to heat
HPG92_RS15285	COG2062	phosphohistidine phosphatase, SixA
HPG92_RS15300	COG3691	Protein conserved in bacteria
HPG92_RS15315	COG2116	formate transmembrane transporter activity
HPG92_RS15345	COG1560	Kdo2-lipid A biosynthetic process
HPG92_RS15360	COG0436	Aminotransferase
HPG92_RS15370	COG0038	chloride channel
HPG92_RS15380	COG0667	Aldo Keto reductase
HPG92_RS15395	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HPG92_RS15415	COG3415	Transposase
HPG92_RS15420	COG3415	Transposase
HPG92_RS15450	COG0583	DNA-binding transcription factor activity
HPG92_RS15455	COG0385	Bile acid
HPG92_RS15460	COG3530	Putative quorum-sensing-regulated virulence factor
HPG92_RS15485	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HPG92_RS15530	COG4208	sulfate ABC transporter
HPG92_RS15550	COG2837	iron assimilation
HPG92_RS15555	COG4974	Belongs to the 'phage' integrase family
HPG92_RS15655	COG4695	Portal protein
HPG92_RS15735	COG5301	cellulose 1,4-beta-cellobiosidase activity
HPG92_RS15825	COG0641	radical SAM
HPG92_RS15830	COG3119	arylsulfatase activity
HPG92_RS15845	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HPG92_RS15855	COG5342	invasion associated locus B
HPG92_RS15870	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HPG92_RS15870	COG0493	'glutamate synthase
HPG92_RS15875	COG3850	Histidine kinase
HPG92_RS15880	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HPG92_RS15890	COG1393	Belongs to the ArsC family
HPG92_RS15910	COG2321	neutral zinc metallopeptidase
HPG92_RS15920	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
HPG92_RS15925	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HPG92_RS15930	COG2716	regulation of RNA biosynthetic process
HPG92_RS15935	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HPG92_RS15940	COG1929	Belongs to the glycerate kinase type-1 family
HPG92_RS15950	COG3835	regulator
HPG92_RS15955	COG0628	permease
HPG92_RS15965	COG1393	Belongs to the ArsC family
HPG92_RS15975	COG2233	PERMEase
HPG92_RS15990	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HPG92_RS16005	COG2200	EAL domain
HPG92_RS16025	COG0516	GMP reductase activity
HPG92_RS16025	COG0517	IMP dehydrogenase activity
HPG92_RS16045	COG1645	bacterial-type flagellum-dependent swarming motility
HPG92_RS16060	COG2976	Protein conserved in bacteria
HPG92_RS16100	COG0437	4 iron, 4 sulfur cluster binding
HPG92_RS16105	COG0243	molybdopterin cofactor binding
HPG92_RS16110	COG4953	penicillin-binding protein 1C
HPG92_RS16115	COG2373	Large extracellular alpha-helical protein
HPG92_RS16120	COG2897	thiosulfate sulfurtransferase activity
HPG92_RS16135	COG2975	iron-sulfur cluster assembly
HPG92_RS16140	COG0633	Ferredoxin
HPG92_RS16160	COG0822	iron-sulfur transferase activity
HPG92_RS16200	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
HPG92_RS16210	COG3711	transcriptional antiterminator
HPG92_RS16215	COG2814	Major facilitator Superfamily
HPG92_RS16225	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HPG92_RS16225	COG1017	nitric oxide dioxygenase activity
HPG92_RS16230	COG3710	Transcriptional regulator
HPG92_RS16235	COG0531	amino acid
HPG92_RS16245	COG3104	oligopeptide transport
HPG92_RS16250	COG0347	Belongs to the P(II) protein family
HPG92_RS16255	COG2204	response regulator
HPG92_RS16260	COG3170	Tfp pilus assembly protein FimV
HPG92_RS16265	COG2205	protein histidine kinase activity
HPG92_RS16290	COG0560	Phosphoserine phosphatase
HPG92_RS16295	COG1263	PTS System
HPG92_RS16295	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HPG92_RS16305	COG1737	Transcriptional regulator
HPG92_RS16310	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HPG92_RS16350	COG3086	response to oxidative stress
HPG92_RS16375	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HPG92_RS16385	COG0513	Belongs to the DEAD box helicase family
HPG92_RS16400	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HPG92_RS16405	COG3118	belongs to the thioredoxin family
HPG92_RS16420	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HPG92_RS16425	COG5544	Lipoprotein
HPG92_RS16430	COG0477	Major facilitator Superfamily
HPG92_RS16460	COG0542	response to heat
HPG92_RS16475	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HPG92_RS16480	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HPG92_RS16490	COG1605	Chorismate mutase
HPG92_RS16490	COG0077	Prephenate dehydratase
HPG92_RS16500	COG0287	Prephenate dehydrogenase
HPG92_RS16500	COG1605	Chorismate mutase
HPG92_RS16530	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HPG92_RS16535	COG4137	Cytochrome C assembly protein
HPG92_RS16540	COG4536	flavin adenine dinucleotide binding
HPG92_RS16555	COG0497	DNA recombination
HPG92_RS16600	COG3021	interspecies interaction between organisms
HPG92_RS16665	COG3023	N-Acetylmuramoyl-L-alanine amidase
HPG92_RS16680	COG1132	(ABC) transporter
HPG92_RS16690	COG2819	hydrolase of the alpha beta superfamily
HPG92_RS16705	COG2990	Protein conserved in bacteria
HPG92_RS16710	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
HPG92_RS16715	COG0642	Histidine kinase
HPG92_RS16745	COG0579	oxidoreductase
HPG92_RS16750	COG1012	belongs to the aldehyde dehydrogenase family
HPG92_RS16755	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HPG92_RS16760	COG1113	amino acid transport
HPG92_RS16765	COG1802	Transcriptional regulator
HPG92_RS16770	COG1652	LysM domain
HPG92_RS16775	COG0401	homolog of Blt101
HPG92_RS16780	COG0640	Transcriptional regulator
HPG92_RS16785	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HPG92_RS16810	COG4575	ribosome binding
HPG92_RS16840	COG4176	ABC-type proline glycine betaine transport system permease component
HPG92_RS16850	COG2814	Major facilitator Superfamily
HPG92_RS16855	COG1846	Transcriptional regulator
HPG92_RS16860	COG1566	PFAM secretion protein HlyD family protein
HPG92_RS16865	COG2814	Major facilitator Superfamily
HPG92_RS16880	COG1238	metal cluster binding
HPG92_RS16885	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HPG92_RS16915	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HPG92_RS16935	COG1546	Belongs to the CinA family
HPG92_RS16940	COG2951	lytic endotransglycosylase activity
HPG92_RS16945	COG3730	PTS system glucitol sorbitol-specific
HPG92_RS16950	COG3732	PTS system glucitol sorbitol-specific
HPG92_RS16955	COG3731	PTS system glucitol sorbitol-specific IIA component
HPG92_RS16960	COG1028	Short-chain dehydrogenase reductase Sdr
HPG92_RS16965	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
HPG92_RS16970	COG1349	DNA-binding transcription factor activity
HPG92_RS16975	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HPG92_RS16975	COG0517	IMP dehydrogenase activity
HPG92_RS16995	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
HPG92_RS17000	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HPG92_RS17005	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HPG92_RS17015	COG3260	NADH ubiquinone oxidoreductase 20
HPG92_RS17020	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HPG92_RS17025	COG3261	NADH dehydrogenase
HPG92_RS17025	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
HPG92_RS17030	COG0650	Formate hydrogenlyase subunit 4
HPG92_RS17035	COG0651	ATP synthesis coupled electron transport
HPG92_RS17040	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HPG92_RS17055	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HPG92_RS17060	COG0298	carbon dioxide binding
HPG92_RS17065	COG0409	Hydrogenase expression formation protein
HPG92_RS17070	COG0309	Hydrogenase expression formation protein (HypE)
HPG92_RS17090	COG1121	(ABC) transporter
HPG92_RS17095	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HPG92_RS17100	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HPG92_RS17160	COG0741	lytic transglycosylase activity
HPG92_RS17180	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HPG92_RS17270	COG2207	Transcriptional regulator
HPG92_RS17365	COG0477	Major facilitator Superfamily
HPG92_RS17375	COG2610	gluconate transmembrane transporter activity
HPG92_RS17380	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HPG92_RS17385	COG3622	Belongs to the hyi family
HPG92_RS17390	COG0235	Class ii aldolase
HPG92_RS17400	COG2084	Dehydrogenase
HPG92_RS17405	COG1349	DNA-binding transcription factor activity
HPG92_RS17415	COG0163	prenyltransferase activity
HPG92_RS17420	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HPG92_RS17495	COG2234	aminopeptidase activity
HPG92_RS17520	COG0720	synthase
HPG92_RS17525	COG0321	lipoyl(octanoyl) transferase activity
HPG92_RS17525	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HPG92_RS17530	COG0602	queuosine metabolic process
HPG92_RS17545	COG3956	TIGRFAM MazG family protein
HPG92_RS17550	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HPG92_RS17560	COG4999	Histidine kinase
HPG92_RS17560	COG3850	Histidine kinase
HPG92_RS17560	COG3437	response regulator, receiver
HPG92_RS17560	COG2205	protein histidine kinase activity
HPG92_RS17570	COG0716	FMN binding
HPG92_RS17580	COG3098	single-species biofilm formation
HPG92_RS17595	COG1611	Belongs to the LOG family
HPG92_RS17600	COG0814	amino acid
HPG92_RS17605	COG1760	l-serine dehydratase
HPG92_RS17615	COG1454	alcohol dehydrogenase
HPG92_RS17620	COG0235	Class ii aldolase
HPG92_RS17625	COG0738	Major facilitator superfamily
HPG92_RS17645	COG1349	DNA-binding transcription factor activity
HPG92_RS17655	COG2363	Small membrane protein
HPG92_RS17660	COG0583	DNA-binding transcription factor activity
HPG92_RS17670	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HPG92_RS17675	COG2166	iron-sulfur cluster assembly
HPG92_RS17685	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HPG92_RS17690	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HPG92_RS17705	COG0860	N-Acetylmuramoyl-L-alanine amidase
HPG92_RS17710	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HPG92_RS17710	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HPG92_RS17715	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HPG92_RS17720	COG1074	ATP-dependent DNA helicase activity
HPG92_RS17730	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HPG92_RS17735	COG4967	type IV pilus modification protein PilV
HPG92_RS17745	COG4795	General secretion pathway protein
HPG92_RS17750	COG2165	general secretion pathway protein
HPG92_RS17780	COG0861	Integral membrane protein TerC family
HPG92_RS17790	COG0667	Aldo Keto reductase
HPG92_RS17810	COG1609	Transcriptional regulator
HPG92_RS17820	COG0583	DNA-binding transcription factor activity
HPG92_RS17825	COG1794	racemase activity, acting on amino acids and derivatives
HPG92_RS17830	COG2814	Major facilitator Superfamily
HPG92_RS17835	COG1028	Short-chain dehydrogenase reductase Sdr
HPG92_RS17845	COG0183	Belongs to the thiolase family
HPG92_RS17860	COG0814	amino acid
HPG92_RS17870	COG3468	outer membrane autotransporter barrel domain protein
HPG92_RS17965	COG3561	AntA/AntB antirepressor
HPG92_RS17985	COG0582	viral genome integration into host DNA
HPG92_RS17995	COG4942	peptidase
HPG92_RS18040	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HPG92_RS18050	COG1272	protein, Hemolysin III
HPG92_RS18060	COG2723	6-phospho-beta-galactosidase activity
HPG92_RS18080	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HPG92_RS18085	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HPG92_RS18090	COG0006	proline dipeptidase activity
HPG92_RS18110	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HPG92_RS18115	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HPG92_RS18130	COG2968	Membrane
HPG92_RS18140	COG0668	transmembrane transport
HPG92_RS18145	COG0191	fructose-bisphosphate aldolase activity
HPG92_RS18175	COG1122	ATPase activity
HPG92_RS18180	COG1122	ATPase activity
HPG92_RS18185	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HPG92_RS18190	COG0501	Belongs to the peptidase M48B family
HPG92_RS18200	COG1166	arginine decarboxylase activity
HPG92_RS18225	COG2814	Major facilitator Superfamily
HPG92_RS18235	COG2356	endonuclease I
HPG92_RS18240	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HPG92_RS18265	COG2805	Type II/IV secretion system protein
HPG92_RS18270	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HPG92_RS18275	COG0762	integral membrane protein
HPG92_RS18290	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HPG92_RS18295	COG0252	asparaginase activity
HPG92_RS18305	COG3171	Protein conserved in bacteria
HPG92_RS18335	COG1982	Orn Lys Arg decarboxylase major
HPG92_RS18340	COG1811	Na channel or pump
HPG92_RS18350	COG0582	viral genome integration into host DNA
HPG92_RS18375	COG4397	Mu-like prophage major head subunit gpT
HPG92_RS18455	COG1022	Amp-dependent synthetase and ligase
HPG92_RS18465	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HPG92_RS18465	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HPG92_RS18510	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HPG92_RS18530	COG0583	DNA-binding transcription factor activity
HPG92_RS18590	COG2835	tetraacyldisaccharide 4'-kinase activity
HPG92_RS18605	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HPG92_RS18615	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HPG92_RS18620	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
HPG92_RS18620	COG0028	Belongs to the TPP enzyme family
HPG92_RS18630	COG2211	Major facilitator Superfamily
HPG92_RS18635	COG1028	Short-chain dehydrogenase reductase Sdr
HPG92_RS18710	COG2030	dehydratase
HPG92_RS18745	COG0531	amino acid
HPG92_RS18760	COG1012	belongs to the aldehyde dehydrogenase family
HPG92_RS18780	COG2271	Major facilitator Superfamily
HPG92_RS18790	COG0246	Mannitol dehydrogenase
HPG92_RS18805	COG0754	glutathionylspermidine amidase activity
HPG92_RS18810	COG0625	glutathione transferase activity
HPG92_RS18825	COG0298	carbon dioxide binding
HPG92_RS18835	COG1773	rubredoxin
HPG92_RS18840	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HPG92_RS18845	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
HPG92_RS18850	COG5557	Pfam Polysulphide reductase, NrfD
HPG92_RS18855	COG0437	4 iron, 4 sulfur cluster binding
HPG92_RS18860	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
HPG92_RS18870	COG0840	transmembrane signaling receptor activity
HPG92_RS18895	COG1028	Short-chain dehydrogenase reductase Sdr
HPG92_RS18900	COG0848	biopolymer transport protein
HPG92_RS18920	COG2207	Transcriptional regulator
HPG92_RS18925	COG1979	alcohol dehydrogenase
HPG92_RS18935	COG0471	metal ion transport
HPG92_RS18965	COG3157	Type VI secretion system effector, Hcp
HPG92_RS18975	COG3111	PFAM Bacterial OB fold (BOF) protein
HPG92_RS18985	COG0642	Histidine kinase
HPG92_RS18990	COG2249	NAD(P)H dehydrogenase (quinone) activity
HPG92_RS18995	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HPG92_RS19005	COG3150	esterase
HPG92_RS19010	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HPG92_RS19015	COG3151	Protein conserved in bacteria
HPG92_RS19020	COG0494	nUDIX hydrolase
HPG92_RS19035	COG0754	glutathionylspermidine amidase activity
HPG92_RS19040	COG3384	dioxygenase
HPG92_RS19090	COG3025	triphosphatase activity
HPG92_RS19095	COG4991	sh3 domain protein
HPG92_RS19110	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HPG92_RS19130	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HPG92_RS19205	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HPG92_RS19320	COG4695	Portal protein
HPG92_RS19370	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HPG92_RS19410	COG0582	viral genome integration into host DNA
HPG92_RS19420	COG2375	cellular response to nickel ion
HPG92_RS19425	COG1695	Transcriptional regulator
HPG92_RS19430	COG0840	transmembrane signaling receptor activity
HPG92_RS19435	COG0840	transmembrane signaling receptor activity
HPG92_RS19450	COG0446	pyridine nucleotide-disulphide oxidoreductase
HPG92_RS19450	COG1902	pentaerythritol trinitrate reductase activity
HPG92_RS19460	COG1451	nucleotide metabolic process
HPG92_RS19470	COG0673	inositol 2-dehydrogenase activity
HPG92_RS19485	COG2721	sulfolactate sulfo-lyase activity
HPG92_RS19495	COG2271	Major facilitator Superfamily
HPG92_RS19500	COG2186	Transcriptional regulator
HPG92_RS19505	COG0586	Pfam SNARE associated Golgi protein
HPG92_RS19515	COG1422	Protein of unknown function (DUF1090)
HPG92_RS19520	COG4575	ribosome binding
HPG92_RS19525	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
HPG92_RS19535	COG2259	Doxx family
HPG92_RS19540	COG0435	Glutathione S-transferase
HPG92_RS19545	COG3152	Membrane
HPG92_RS19550	COG0583	DNA-binding transcription factor activity
HPG92_RS19555	COG1741	Belongs to the pirin family
HPG92_RS19570	COG0814	amino acid
HPG92_RS19575	COG1760	l-serine dehydratase
HPG92_RS19580	COG1882	Formate acetyltransferase
HPG92_RS19600	COG0583	DNA-binding transcription factor activity
HPG92_RS19615	COG1349	DNA-binding transcription factor activity
HPG92_RS19625	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HPG92_RS19630	COG2222	sugar isomerase
HPG92_RS19640	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HPG92_RS19660	COG2823	Periplasmic or secreted lipoprotein
HPG92_RS19665	COG0702	epimerase
HPG92_RS19670	COG0693	protein deglycase activity
HPG92_RS19685	COG3153	acetyltransferase
HPG92_RS19690	COG3154	lipid carrier protein
HPG92_RS19695	COG0826	peptidase U32
HPG92_RS19700	COG0826	peptidase U32
HPG92_RS19705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HPG92_RS19710	COG0814	amino acid
HPG92_RS19715	COG0513	Belongs to the DEAD box helicase family
HPG92_RS19780	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HPG92_RS19790	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HPG92_RS19805	COG1534	Rna-binding protein
HPG92_RS19815	COG2027	D-alanyl-D-alanine carboxypeptidase
HPG92_RS19825	COG0697	spore germination
HPG92_RS19840	COG0142	geranyltranstransferase activity
HPG92_RS19845	COG3423	Transcriptional regulator
HPG92_RS19855	COG5007	Belongs to the BolA IbaG family
HPG92_RS19860	COG3113	response to antibiotic
HPG92_RS19865	COG2854	intermembrane phospholipid transfer
HPG92_RS19870	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HPG92_RS19875	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HPG92_RS19880	COG1127	ABC transporter
HPG92_RS19885	COG0530	calcium, potassium:sodium antiporter activity
HPG92_RS19895	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HPG92_RS19900	COG3117	lipopolysaccharide transmembrane transporter activity
HPG92_RS19905	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HPG92_RS19910	COG1137	ATPase activity
HPG92_RS19935	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HPG92_RS19940	COG0515	serine threonine protein kinase
HPG92_RS19950	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
HPG92_RS19955	COG0784	Response regulator, receiver
HPG92_RS19955	COG2198	Histidine kinase
HPG92_RS19955	COG5002	protein histidine kinase activity
HPG92_RS19960	COG1242	4 iron, 4 sulfur cluster binding
HPG92_RS19965	COG0069	glutamate synthase activity
HPG92_RS19965	COG0067	glutamate synthase
HPG92_RS19965	COG0070	glutamate synthase
HPG92_RS19970	COG0493	'glutamate synthase
HPG92_RS19985	COG0402	S-adenosylhomocysteine deaminase activity
HPG92_RS19990	COG2731	YhcH YjgK YiaL family protein
HPG92_RS20020	COG2969	positive regulation of protein catabolic process
HPG92_RS20025	COG0625	glutathione transferase activity
HPG92_RS20045	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HPG92_RS20050	COG3105	Protein conserved in bacteria
HPG92_RS20055	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HPG92_RS20085	COG2732	(Barnase) inhibitor
HPG92_RS20105	COG0583	DNA-binding transcription factor activity
HPG92_RS20115	COG0312	modulator of DNA gyrase
HPG92_RS20120	COG3164	Protein of unknown function
HPG92_RS20125	COG1530	ribonuclease E activity
HPG92_RS20135	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HPG92_RS20140	COG1792	Involved in formation and maintenance of cell shape
HPG92_RS20145	COG1077	Cell shape determining protein MreB Mrl
HPG92_RS20150	COG2200	EAL domain
HPG92_RS20150	COG2199	diguanylate cyclase activity
HPG92_RS20155	COG0604	alcohol dehydrogenase
HPG92_RS20170	COG0511	ligase activity, forming carbon-carbon bonds
HPG92_RS20175	COG0439	Biotin carboxylase
HPG92_RS20180	COG3924	membrane
HPG92_RS20185	COG4145	pantothenate transmembrane transporter activity
HPG92_RS20205	COG2189	Belongs to the N(4) N(6)-methyltransferase family
HPG92_RS20220	COG1309	transcriptional regulator
HPG92_RS20225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HPG92_RS20230	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HPG92_RS20280	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HPG92_RS20300	COG0551	DNA topoisomerase type I activity
HPG92_RS20310	COG0758	DNA mediated transformation
HPG92_RS20340	COG3036	rescue of stalled ribosome
HPG92_RS20345	COG0789	Transcriptional regulator
HPG92_RS20385	COG0201	protein transport
HPG92_RS20465	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HPG92_RS20490	COG0051	transcription antitermination factor activity, RNA binding
HPG92_RS20545	COG2964	Protein conserved in bacteria
HPG92_RS20550	COG0545	Peptidyl-prolyl cis-trans isomerase
HPG92_RS20560	COG1047	Peptidyl-prolyl cis-trans
HPG92_RS20565	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HPG92_RS20580	COG0488	(ABC) transporter
HPG92_RS20600	COG3954	Phosphoribulokinase
HPG92_RS20605	COG1765	OsmC-like protein
HPG92_RS20615	COG1289	transmembrane transporter activity
HPG92_RS20650	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HPG92_RS20685	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HPG92_RS20690	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HPG92_RS20695	COG3266	domain, Protein
HPG92_RS20710	COG4796	Type ii and iii secretion system protein
HPG92_RS20725	COG3166	PFAM Fimbrial assembly family protein
HPG92_RS20730	COG4972	Pilus assembly protein
HPG92_RS20735	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HPG92_RS20740	COG0494	nUDIX hydrolase
HPG92_RS20750	COG1011	Hydrolase
HPG92_RS20755	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HPG92_RS20765	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HPG92_RS20780	COG0745	RESPONSE REGULATOR receiver
HPG92_RS20785	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HPG92_RS20790	COG2183	response to ionizing radiation
HPG92_RS20795	COG1918	ferrous iron import across plasma membrane
HPG92_RS20810	COG5464	transposase or invertase
HPG92_RS20820	COG1040	competence protein
HPG92_RS20830	COG2610	gluconate transmembrane transporter activity
HPG92_RS20835	COG1640	4-alpha-glucanotransferase
HPG92_RS20840	COG0058	SHG alpha-glucan phosphorylase activity
HPG92_RS20850	COG1349	DNA-binding transcription factor activity
HPG92_RS20865	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HPG92_RS20870	COG0058	SHG alpha-glucan phosphorylase activity
HPG92_RS20890	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HPG92_RS20905	COG2610	gluconate transmembrane transporter activity
HPG92_RS20910	COG3265	gluconokinase activity
HPG92_RS20915	COG1609	Transcriptional regulator
HPG92_RS20920	COG1741	Belongs to the pirin family
HPG92_RS20925	COG0673	inositol 2-dehydrogenase activity
HPG92_RS20930	COG1247	-acetyltransferase
HPG92_RS20935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HPG92_RS20950	COG1735	metal-dependent hydrolase with the TIM-barrel fold
HPG92_RS20955	COG0405	Gamma-glutamyltransferase
HPG92_RS20965	COG0584	glycerophosphoryl diester phosphodiesterase
HPG92_RS21035	COG2177	Part of the ABC transporter FtsEX involved in
HPG92_RS21040	COG2884	Cell division ATP-binding protein ftsE
HPG92_RS21045	COG0552	protein localization to endoplasmic reticulum
HPG92_RS21050	COG0742	ribosomal rna small subunit methyltransferase
HPG92_RS21055	COG3776	membrane
HPG92_RS21065	COG3714	YhhN family
HPG92_RS21085	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HPG92_RS21100	COG0628	permease
HPG92_RS21105	COG2091	lysine biosynthetic process via aminoadipic acid
HPG92_RS21115	COG0842	Transport permease protein
HPG92_RS21125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HPG92_RS21130	COG2081	HI0933 family
HPG92_RS21165	COG0671	phosphoesterase, PA-phosphatase related
HPG92_RS21170	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HPG92_RS21175	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HPG92_RS21195	COG2197	response regulator
HPG92_RS21200	COG0583	DNA-binding transcription factor activity
HPG92_RS21205	COG1295	ribonuclease BN
HPG92_RS21215	COG2982	Protein involved in outer membrane biogenesis
HPG92_RS21220	COG2200	EAL domain
HPG92_RS21225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HPG92_RS21240	COG2199	diguanylate cyclase activity
HPG92_RS21240	COG2200	EAL domain
HPG92_RS21255	COG1215	transferase activity, transferring glycosyl groups
HPG92_RS21260	COG1215	transferase activity, transferring glycosyl groups
HPG92_RS21300	COG0814	amino acid
HPG92_RS21305	COG4608	Belongs to the ABC transporter superfamily
HPG92_RS21310	COG0444	Belongs to the ABC transporter superfamily
HPG92_RS21315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HPG92_RS21325	COG0747	negative chemotaxis
HPG92_RS21345	COG5571	outer membrane autotransporter
HPG92_RS21350	COG2818	Glycosylase
HPG92_RS21355	COG0456	acetyltransferase
HPG92_RS21360	COG0243	molybdopterin cofactor binding
HPG92_RS21365	COG2885	chlorophyll binding
HPG92_RS21380	COG2944	sequence-specific DNA binding
HPG92_RS21385	COG1278	Cold shock
HPG92_RS21410	COG3274	enterobacterial common antigen metabolic process
HPG92_RS21420	COG1070	Carbohydrate kinase
HPG92_RS21430	COG1609	Transcriptional regulator
HPG92_RS21430	COG2207	Transcriptional regulator
HPG92_RS21435	COG2992	FlgJ-related protein
HPG92_RS21440	COG0366	Alpha amylase catalytic
HPG92_RS21445	COG3977	Valine--pyruvate aminotransferase
HPG92_RS21455	COG1414	Transcriptional regulator
HPG92_RS21465	COG2731	YhcH YjgK YiaL family protein
HPG92_RS21475	COG2271	Major facilitator Superfamily
HPG92_RS21480	COG1070	Carbohydrate kinase
HPG92_RS21485	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
HPG92_RS21490	COG3623	hexulose-6-phosphate isomerase
HPG92_RS21495	COG0235	Class ii aldolase
HPG92_RS21505	COG2211	Major facilitator Superfamily
HPG92_RS21515	COG1012	belongs to the aldehyde dehydrogenase family
HPG92_RS21520	COG1940	carbohydrate kinase activity
HPG92_RS21525	COG1454	alcohol dehydrogenase
HPG92_RS21530	COG3276	selenocysteine insertion sequence binding
HPG92_RS21540	COG0625	glutathione transferase activity
HPG92_RS21545	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HPG92_RS21545	COG2213	PTS system mannitol-specific
HPG92_RS21555	COG3722	fumarate hydratase activity
HPG92_RS21575	COG2186	Transcriptional regulator
HPG92_RS21585	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HPG92_RS21605	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HPG92_RS21610	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HPG92_RS21625	COG2861	carbohydrate metabolic process
HPG92_RS21630	COG1216	Glycosyl transferase, family 2
HPG92_RS21700	COG0438	transferase activity, transferring glycosyl groups
HPG92_RS21705	COG0859	PFAM glycosyl transferase family 9
HPG92_RS21710	COG1519	Transferase
HPG92_RS21740	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HPG92_RS21765	COG1561	YicC-like family, N-terminal region
HPG92_RS21770	COG0583	DNA-binding transcription factor activity
HPG92_RS21780	COG2860	membrane
HPG92_RS21800	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HPG92_RS21805	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HPG92_RS21810	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HPG92_RS21815	COG0786	glutamate:sodium symporter activity
HPG92_RS21820	COG2233	PERMEase
HPG92_RS21825	COG2982	Protein involved in outer membrane biogenesis
HPG92_RS21830	COG1501	Belongs to the glycosyl hydrolase 31 family
HPG92_RS21835	COG2211	Major facilitator Superfamily
HPG92_RS21845	COG1335	isochorismatase
HPG92_RS21875	COG1285	pathogenesis
HPG92_RS21890	COG4974	Belongs to the 'phage' integrase family
HPG92_RS21895	COG0582	viral genome integration into host DNA
HPG92_RS21900	COG4974	Belongs to the 'phage' integrase family
HPG92_RS21920	COG3716	PTS system mannose fructose sorbose family IID component
HPG92_RS21925	COG3715	PTS system
HPG92_RS21930	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HPG92_RS21930	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HPG92_RS21950	COG2723	6-phospho-beta-galactosidase activity
HPG92_RS21990	COG0738	Major facilitator superfamily
HPG92_RS22000	COG1349	DNA-binding transcription factor activity
HPG92_RS22005	COG0440	acetolactate synthase activity
HPG92_RS22010	COG0028	Belongs to the TPP enzyme family
HPG92_RS22035	COG2814	Major facilitator Superfamily
HPG92_RS22045	COG0641	radical SAM
HPG92_RS22055	COG2149	membrane
HPG92_RS22065	COG0071	Belongs to the small heat shock protein (HSP20) family
HPG92_RS22075	COG5645	(Lipo)protein
HPG92_RS22080	COG0823	Involved in the tonB-independent uptake of proteins
HPG92_RS22085	COG3088	subunit of a heme lyase
HPG92_RS22085	COG4235	cytochrome complex assembly
HPG92_RS22090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HPG92_RS22095	COG1138	Cytochrome C-type biogenesis protein
HPG92_RS22105	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HPG92_RS22110	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HPG92_RS22115	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HPG92_RS22120	COG4133	protoheme IX ABC transporter activity
HPG92_RS22125	COG1858	cytochrome C peroxidase
HPG92_RS22140	COG3005	denitrification pathway
HPG92_RS22145	COG0745	RESPONSE REGULATOR receiver
HPG92_RS22150	COG1879	ABC-type sugar transport system periplasmic component
HPG92_RS22155	COG0784	Response regulator, receiver
HPG92_RS22155	COG2205	protein histidine kinase activity
HPG92_RS22155	COG2198	Histidine kinase
HPG92_RS22175	COG0561	phosphatase activity
HPG92_RS22185	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HPG92_RS22275	COG2091	lysine biosynthetic process via aminoadipic acid
HPG92_RS22280	COG0431	NADPH-dependent FMN reductase
HPG92_RS22285	COG2252	PERMEase
HPG92_RS22290	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HPG92_RS22295	COG0704	Plays a role in the regulation of phosphate uptake
HPG92_RS22305	COG0581	inorganic phosphate transmembrane transporter activity
HPG92_RS22310	COG0573	inorganic phosphate transmembrane transporter activity
HPG92_RS22315	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HPG92_RS22370	COG3312	ion transport
HPG92_RS22385	COG0716	FMN binding
HPG92_RS22390	COG1522	sequence-specific DNA binding
HPG92_RS22425	COG1172	Belongs to the binding-protein-dependent transport system permease family
HPG92_RS22435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HPG92_RS22440	COG1609	Transcriptional regulator
HPG92_RS22450	COG2186	Transcriptional regulator
HPG92_RS22510	COG3978	acetolactate synthase activity
HPG92_RS22535	COG3414	Phosphotransferase system galactitol-specific IIB component
HPG92_RS22540	COG3775	system Galactitol-specific IIC component
HPG92_RS22555	COG2376	Dihydroxyacetone kinase
HPG92_RS22575	COG1461	Dihydroxyacetone kinase
HPG92_RS22580	COG2376	Dihydroxyacetone kinase
HPG92_RS22645	COG3118	belongs to the thioredoxin family
HPG92_RS22660	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HPG92_RS22675	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HPG92_RS22680	COG1088	dTDP-glucose 4,6-dehydratase activity
HPG92_RS22685	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HPG92_RS22690	COG0456	acetyltransferase
HPG92_RS22695	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HPG92_RS22700	COG2244	polysaccharide biosynthetic process
HPG92_RS22745	COG3071	HemY protein
HPG92_RS22750	COG2959	enzyme of heme biosynthesis
HPG92_RS22795	COG1011	Hydrolase
HPG92_RS22845	COG1280	lysine exporter protein (LysE YggA)
HPG92_RS22850	COG2267	carboxylic ester hydrolase activity
HPG92_RS22855	COG0561	phosphatase activity
HPG92_RS22875	COG0641	radical SAM
HPG92_RS22920	COG0805	protein transport
HPG92_RS22935	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HPG92_RS22960	COG1739	Uncharacterized protein family UPF0029
HPG92_RS23005	COG1763	Mo-molybdopterin cofactor biosynthetic process
HPG92_RS23010	COG0746	molybdenum cofactor guanylyltransferase activity
HPG92_RS23015	COG3084	Protein conserved in bacteria
HPG92_RS23030	COG0204	Acyl-transferase
HPG92_RS23105	COG1501	Belongs to the glycosyl hydrolase 31 family
HPG92_RS23110	COG2017	converts alpha-aldose to the beta-anomer
HPG92_RS23120	COG3684	Belongs to the aldolase LacD family
HPG92_RS23135	COG1349	DNA-binding transcription factor activity
HPG92_RS23140	COG1011	Hydrolase
HPG92_RS23155	COG0456	acetyltransferase
HPG92_RS23165	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HPG92_RS23180	COG2864	formate dehydrogenase
HPG92_RS23185	COG0437	4 iron, 4 sulfur cluster binding