locus-tag	class	description
AL463_RS00035	COG3180	Ammonia monooxygenase
AL463_RS00200	COG1982	Orn Lys Arg decarboxylase major
AL463_RS00360	COG0367	asparagine synthase
AL463_RS00445	COG0443	Heat shock 70 kDa protein
AL463_RS00485	COG3829	transcription factor binding
AL463_RS00485	COG3290	protein histidine kinase activity
AL463_RS00565	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AL463_RS00585	COG3180	Ammonia monooxygenase
AL463_RS00610	COG1216	Glycosyl transferase, family 2
AL463_RS00650	COG0582	viral genome integration into host DNA
AL463_RS00665	COG1984	allophanate hydrolase subunit 2
AL463_RS00670	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AL463_RS00715	COG2205	protein histidine kinase activity
AL463_RS00720	COG0745	RESPONSE REGULATOR receiver
AL463_RS00730	COG1982	Orn Lys Arg decarboxylase major
AL463_RS00735	COG0531	amino acid
AL463_RS00745	COG0033	Phosphoglucomutase
AL463_RS00755	COG0596	Alpha beta hydrolase
AL463_RS00770	COG0735	belongs to the Fur family
AL463_RS00775	COG0583	DNA-binding transcription factor activity
AL463_RS00780	COG1053	succinate dehydrogenase
AL463_RS00820	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AL463_RS00825	COG1940	carbohydrate kinase activity
AL463_RS00825	COG1846	Transcriptional regulator
AL463_RS00830	COG0647	UMP catabolic process
AL463_RS00835	COG0367	asparagine synthase
AL463_RS00880	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL463_RS00890	COG1702	phosphate starvation-inducible protein PhoH
AL463_RS00915	COG0765	amino acid transport
AL463_RS00920	COG0765	amino acid transport
AL463_RS00925	COG1126	abc transporter atp-binding protein
AL463_RS00940	COG0443	Heat shock 70 kDa protein
AL463_RS00945	COG2214	Heat shock protein DnaJ domain protein
AL463_RS00955	COG2214	Heat shock protein DnaJ domain protein
AL463_RS00970	COG2888	peptidyl-tyrosine sulfation
AL463_RS00975	COG3290	protein histidine kinase activity
AL463_RS00975	COG3829	transcription factor binding
AL463_RS01005	COG1466	dna polymerase III delta subunit
AL463_RS01030	COG0799	negative regulation of ribosome biogenesis
AL463_RS01040	COG0768	penicillin binding
AL463_RS01045	COG0772	Belongs to the SEDS family
AL463_RS01055	COG1686	Belongs to the peptidase S11 family
AL463_RS01070	COG0583	DNA-binding transcription factor activity
AL463_RS01085	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL463_RS01105	COG3069	C4-dicarboxylate transmembrane transporter activity
AL463_RS01110	COG4565	transcriptional regulatory protein
AL463_RS01115	COG3290	protein histidine kinase activity
AL463_RS01120	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
AL463_RS01130	COG2301	Belongs to the HpcH HpaI aldolase family
AL463_RS01135	COG3051	citrate lyase alpha subunit
AL463_RS01150	COG0471	metal ion transport
AL463_RS01155	COG3719	Belongs to the RNase T2 family
AL463_RS01160	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL463_RS01165	COG1063	alcohol dehydrogenase
AL463_RS01185	COG0243	molybdopterin cofactor binding
AL463_RS01205	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL463_RS01210	COG0583	DNA-binding transcription factor activity
AL463_RS01215	COG3969	phosphoadenosine phosphosulfate
AL463_RS01220	COG1475	DNA binding
AL463_RS01225	COG0436	Aminotransferase
AL463_RS01230	COG0371	Dehydrogenase
AL463_RS01235	COG2879	small protein
AL463_RS01240	COG1966	Carbon starvation protein
AL463_RS01250	COG1028	Short-chain dehydrogenase reductase Sdr
AL463_RS01255	COG3433	isochorismatase activity
AL463_RS01255	COG1535	isochorismatase
AL463_RS01260	COG1021	2,3-dihydroxybenzoate-AMP ligase
AL463_RS01265	COG1169	isochorismate synthase
AL463_RS01270	COG4592	Periplasmic binding protein
AL463_RS01280	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL463_RS01285	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL463_RS01290	COG1120	ATPase activity
AL463_RS01295	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
AL463_RS01300	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AL463_RS01300	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AL463_RS01305	COG3251	PFAM MbtH domain protein
AL463_RS01310	COG2382	esterase
AL463_RS01315	COG4771	TonB-dependent receptor
AL463_RS01345	COG2315	Protein conserved in bacteria
AL463_RS01370	COG3716	PTS system mannose fructose sorbose family IID component
AL463_RS01380	COG2222	sugar isomerase
AL463_RS01385	COG3933	PFAM sigma-54 factor interaction domain-containing protein
AL463_RS01385	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AL463_RS01395	COG0668	transmembrane transport
AL463_RS01400	COG1113	amino acid transport
AL463_RS01410	COG3059	membrane
AL463_RS01420	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL463_RS01425	COG2207	Transcriptional regulator
AL463_RS01430	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL463_RS01435	COG5002	protein histidine kinase activity
AL463_RS01445	COG2246	polysaccharide biosynthetic process
AL463_RS01450	COG0463	Glycosyl transferase, family 2
AL463_RS01460	COG0582	viral genome integration into host DNA
AL463_RS01525	COG2501	S4 domain
AL463_RS01530	COG1988	membrane-bound metal-dependent
AL463_RS01550	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AL463_RS01560	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AL463_RS01565	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AL463_RS01570	COG0549	Belongs to the carbamate kinase family
AL463_RS01580	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AL463_RS01585	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AL463_RS01590	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AL463_RS01595	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL463_RS01600	COG3257	ureidoglycine aminohydrolase activity
AL463_RS01605	COG1929	Belongs to the glycerate kinase type-1 family
AL463_RS01610	COG2233	PERMEase
AL463_RS01620	COG1953	Uracil, thiamine, allantoin
AL463_RS01630	COG2084	Dehydrogenase
AL463_RS01635	COG3622	Belongs to the hyi family
AL463_RS01640	COG3960	tartronate-semialdehyde synthase activity
AL463_RS01675	COG1464	Belongs to the NlpA lipoprotein family
AL463_RS01685	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AL463_RS01690	COG4181	ATPase activity
AL463_RS01695	COG2755	lipolytic protein G-D-S-L family
AL463_RS01700	COG0300	oxidoreductase activity
AL463_RS01705	COG3118	belongs to the thioredoxin family
AL463_RS01710	COG0390	transport system, permease component
AL463_RS01715	COG4619	ABC transporter
AL463_RS01720	COG0330	HflC and HflK could
AL463_RS01725	COG1585	Membrane protein implicated in regulation of membrane protease activity
AL463_RS01745	COG3735	TraB family
AL463_RS01760	COG2223	nitrite transmembrane transporter activity
AL463_RS01765	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AL463_RS01765	COG4651	solute:proton antiporter activity
AL463_RS01770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL463_RS01815	COG2832	Protein of unknown function (DUF454)
AL463_RS01820	COG3923	Primosomal replication protein n
AL463_RS01830	COG5464	transposase or invertase
AL463_RS01835	COG1196	nuclear chromosome segregation
AL463_RS01835	COG3264	Mechanosensitive ion channel
AL463_RS01840	COG1309	transcriptional regulator
AL463_RS01845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL463_RS01850	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL463_RS01865	COG0110	maltose O-acetyltransferase activity
AL463_RS01885	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AL463_RS01895	COG3695	enzyme binding
AL463_RS01900	COG3126	Type III secretion system lipoprotein chaperone (YscW)
AL463_RS01905	COG1946	Acyl-CoA thioesterase
AL463_RS01910	COG0004	ammonium transporteR
AL463_RS01915	COG0347	Belongs to the P(II) protein family
AL463_RS01920	COG1132	(ABC) transporter
AL463_RS01925	COG1132	(ABC) transporter
AL463_RS01930	COG1522	sequence-specific DNA binding
AL463_RS01945	COG4533	DNA binding
AL463_RS01955	COG0824	Thioesterase
AL463_RS01960	COG1555	photosystem II stabilization
AL463_RS01965	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL463_RS01975	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AL463_RS01995	COG0271	Belongs to the BolA IbaG family
AL463_RS02000	COG3056	Lipoprotein
AL463_RS02005	COG2223	nitrite transmembrane transporter activity
AL463_RS02010	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AL463_RS02015	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AL463_RS02020	COG1845	cytochrome c oxidase, subunit III
AL463_RS02025	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AL463_RS02045	COG2814	Major facilitator Superfamily
AL463_RS02075	COG2188	Transcriptional regulator
AL463_RS02110	COG0142	geranyltranstransferase activity
AL463_RS02120	COG0667	Aldo Keto reductase
AL463_RS02125	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AL463_RS02145	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL463_RS02145	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL463_RS02155	COG4238	major outer membrane lipoprotein
AL463_RS02185	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL463_RS02195	COG1862	Preprotein translocase
AL463_RS02220	COG0366	Alpha amylase catalytic
AL463_RS02235	COG5002	protein histidine kinase activity
AL463_RS02250	COG0420	3'-5' exonuclease activity
AL463_RS02255	COG0419	ATPase involved in DNA repair
AL463_RS02260	COG2814	Major facilitator Superfamily
AL463_RS02265	COG1940	carbohydrate kinase activity
AL463_RS02280	COG4126	flavin adenine dinucleotide binding
AL463_RS02300	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AL463_RS02305	COG3706	GGDEF domain
AL463_RS02350	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AL463_RS02355	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AL463_RS02370	COG0113	porphobilinogen synthase activity
AL463_RS02405	COG1280	lysine exporter protein (LysE YggA)
AL463_RS02425	COG1294	oxidase, subunit
AL463_RS02430	COG1271	oxidase subunit
AL463_RS02450	COG2814	Major facilitator Superfamily
AL463_RS02465	COG0789	Transcriptional regulator
AL463_RS02475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL463_RS02520	COG2200	EAL domain
AL463_RS02535	COG3539	Fimbrial protein
AL463_RS02540	COG3121	Chaperone
AL463_RS02545	COG3188	usher protein
AL463_RS02580	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL463_RS02595	COG2814	Major facilitator Superfamily
AL463_RS02615	COG2801	Transposase and inactivated derivatives
AL463_RS02655	COG2195	Cleaves the N-terminal amino acid of tripeptides
AL463_RS02660	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AL463_RS02665	COG1690	Belongs to the RtcB family
AL463_RS02675	COG3034	peptidoglycan biosynthetic process
AL463_RS02680	COG0121	glutamine amidotransferase
AL463_RS02695	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL463_RS02785	COG3209	COG3209 Rhs family protein
AL463_RS02795	COG3209	COG3209 Rhs family protein
AL463_RS02840	COG2885	chlorophyll binding
AL463_RS02840	COG3047	cAMP biosynthetic process
AL463_RS02945	COG2226	methyltransferase
AL463_RS02955	COG1388	LysM domain
AL463_RS02955	COG0741	lytic transglycosylase activity
AL463_RS02960	COG2226	methyltransferase
AL463_RS02970	COG2814	Major facilitator Superfamily
AL463_RS02975	COG0583	DNA-binding transcription factor activity
AL463_RS03040	COG1720	tRNA m6t6A37 methyltransferase activity
AL463_RS03055	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AL463_RS03070	COG4568	rho-dependent transcription termination
AL463_RS03080	COG0346	lactoylglutathione lyase activity
AL463_RS03085	COG1982	Orn Lys Arg decarboxylase major
AL463_RS03145	COG0575	Belongs to the CDS family
AL463_RS03195	COG0477	Major facilitator Superfamily
AL463_RS03205	COG3835	regulator
AL463_RS03230	COG2860	membrane
AL463_RS03260	COG3539	Fimbrial protein
AL463_RS03265	COG3539	Fimbrial protein
AL463_RS03270	COG3121	Chaperone
AL463_RS03275	COG3188	usher protein
AL463_RS03290	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL463_RS03295	COG1120	ATPase activity
AL463_RS03300	COG4774	siderophore transport
AL463_RS03305	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AL463_RS03310	COG1643	Atp-dependent helicase
AL463_RS03315	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AL463_RS03340	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AL463_RS03360	COG0726	polysaccharide deacetylase
AL463_RS03365	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL463_RS03385	COG3539	Fimbrial protein
AL463_RS03390	COG0842	Transport permease protein
AL463_RS03395	COG1131	(ABC) transporter
AL463_RS03400	COG0288	reversible hydration of carbon dioxide
AL463_RS03410	COG4993	Dehydrogenase
AL463_RS03435	COG1349	DNA-binding transcription factor activity
AL463_RS03470	COG3064	Membrane
AL463_RS03485	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL463_RS03490	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL463_RS03495	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AL463_RS03510	COG2211	Major facilitator Superfamily
AL463_RS03515	COG3940	Belongs to the glycosyl hydrolase 43 family
AL463_RS03520	COG3725	Membrane protein required for beta-lactamase induction
AL463_RS03535	COG4969	Belongs to the N-Me-Phe pilin family
AL463_RS03540	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AL463_RS03545	COG1459	type II secretion system
AL463_RS03575	COG0494	nUDIX hydrolase
AL463_RS03595	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AL463_RS03600	COG0849	cell division
AL463_RS03625	COG0772	Belongs to the SEDS family
AL463_RS03640	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AL463_RS03650	COG0768	penicillin binding
AL463_RS03740	COG0586	Pfam SNARE associated Golgi protein
AL463_RS03775	COG0417	DNA replication proofreading
AL463_RS03840	COG3119	arylsulfatase activity
AL463_RS03865	COG2271	Major facilitator Superfamily
AL463_RS04025	COG1047	Peptidyl-prolyl cis-trans
AL463_RS04040	COG0196	riboflavin kinase activity
AL463_RS04065	COG0583	DNA-binding transcription factor activity
AL463_RS04085	COG0641	radical SAM
AL463_RS04090	COG3119	arylsulfatase activity
AL463_RS04100	COG0737	Belongs to the 5'-nucleotidase family
AL463_RS04115	COG0583	DNA-binding transcription factor activity
AL463_RS04135	COG3121	Chaperone
AL463_RS04140	COG3539	Fimbrial protein
AL463_RS04155	COG3188	usher protein
AL463_RS04220	COG4735	regulation of single-species biofilm formation
AL463_RS04225	COG1584	GPR1 FUN34 yaaH family protein
AL463_RS04230	COG0521	Mo-molybdopterin cofactor biosynthetic process
AL463_RS04240	COG1115	amino acid carrier protein
AL463_RS04250	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AL463_RS04260	COG0527	aspartate kinase activity
AL463_RS04260	COG0460	homoserine dehydrogenase
AL463_RS04270	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AL463_RS04280	COG0745	RESPONSE REGULATOR receiver
AL463_RS04300	COG3121	Chaperone
AL463_RS04320	COG4452	Inner membrane protein CreD
AL463_RS04325	COG2205	protein histidine kinase activity
AL463_RS04330	COG0745	RESPONSE REGULATOR receiver
AL463_RS04335	COG3045	CreA protein
AL463_RS04340	COG3708	Transcriptional regulator
AL463_RS04340	COG2207	Transcriptional regulator
AL463_RS04365	COG0488	(ABC) transporter
AL463_RS04380	COG0560	Phosphoserine phosphatase
AL463_RS04385	COG3726	membrane protein affecting hemolysin expression
AL463_RS04400	COG3539	Fimbrial protein
AL463_RS04405	COG3121	Chaperone
AL463_RS04410	COG3188	usher protein
AL463_RS04440	COG1328	CTP reductase activity
AL463_RS04445	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AL463_RS04450	COG0084	hydrolase, TatD family'
AL463_RS04465	COG2823	Periplasmic or secreted lipoprotein
AL463_RS04475	COG1011	Hydrolase
AL463_RS04485	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
AL463_RS04515	COG3706	GGDEF domain
AL463_RS04520	COG4114	ferric iron reductase
AL463_RS04525	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AL463_RS04530	COG2197	response regulator
AL463_RS04535	COG2197	response regulator
AL463_RS04540	COG2966	Psort location CytoplasmicMembrane, score
AL463_RS04555	COG1484	DNA-dependent DNA replication
AL463_RS04575	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AL463_RS04580	COG3716	PTS system mannose fructose sorbose family IID component
AL463_RS04585	COG3715	PTS system
AL463_RS04590	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL463_RS04605	COG0840	transmembrane signaling receptor activity
AL463_RS04610	COG1966	Carbon starvation protein
AL463_RS04615	COG2879	small protein
AL463_RS04620	COG0523	cobalamin synthesis protein
AL463_RS04635	COG1715	Restriction endonuclease
AL463_RS04640	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
AL463_RS04675	COG1012	belongs to the aldehyde dehydrogenase family
AL463_RS04680	COG5464	transposase or invertase
AL463_RS04690	COG2733	membrane
AL463_RS04695	COG0477	Major facilitator Superfamily
AL463_RS04705	COG3366	ferrous iron transmembrane transporter activity
AL463_RS04710	COG0700	Nucleoside recognition
AL463_RS04715	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AL463_RS04720	COG0583	DNA-binding transcription factor activity
AL463_RS04745	COG2186	Transcriptional regulator
AL463_RS04750	COG0412	Dienelactone hydrolase
AL463_RS04780	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AL463_RS04815	COG4133	protoheme IX ABC transporter activity
AL463_RS04840	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL463_RS04840	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
AL463_RS04845	COG0582	viral genome integration into host DNA
AL463_RS04855	COG1064	alcohol dehydrogenase
AL463_RS04860	COG3265	gluconokinase activity
AL463_RS04865	COG1063	alcohol dehydrogenase
AL463_RS04870	COG1028	Short-chain dehydrogenase reductase Sdr
AL463_RS04875	COG2610	gluconate transmembrane transporter activity
AL463_RS04880	COG1609	Transcriptional regulator
AL463_RS04885	COG0795	lipopolysaccharide-transporting ATPase activity
AL463_RS04890	COG0795	lipopolysaccharide-transporting ATPase activity
AL463_RS04905	COG2927	DNA polymerase III (CHI subunit)
AL463_RS04945	COG2731	YhcH YjgK YiaL family protein
AL463_RS04965	COG1288	antiporter activity
AL463_RS04970	COG1438	arginine binding
AL463_RS05015	COG0366	Alpha amylase catalytic
AL463_RS05035	COG2026	Addiction module toxin, RelE StbE family
AL463_RS05040	COG3077	Addiction module antitoxin, RelB DinJ family
AL463_RS05045	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL463_RS05045	COG3711	transcriptional antiterminator
AL463_RS05060	COG3964	amidohydrolase
AL463_RS05095	COG0312	modulator of DNA gyrase
AL463_RS05105	COG1082	Xylose isomerase domain protein TIM barrel
AL463_RS05115	COG2814	Major facilitator Superfamily
AL463_RS05120	COG0673	inositol 2-dehydrogenase activity
AL463_RS05125	COG3962	Belongs to the TPP enzyme family
AL463_RS05130	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL463_RS05140	COG1082	Xylose isomerase domain protein TIM barrel
AL463_RS05145	COG5520	Belongs to the glycosyl hydrolase 30 family
AL463_RS05170	COG3718	enzyme involved in inositol metabolism
AL463_RS05175	COG0477	Major facilitator Superfamily
AL463_RS05175	COG2814	Major facilitator Superfamily
AL463_RS05185	COG0477	Major facilitator Superfamily
AL463_RS05185	COG2814	Major facilitator Superfamily
AL463_RS05190	COG1737	Transcriptional regulator
AL463_RS05190	COG0837	glucose binding
AL463_RS05200	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AL463_RS05215	COG3964	amidohydrolase
AL463_RS05220	COG2271	Major facilitator Superfamily
AL463_RS05225	COG2105	PFAM AIG2 family protein
AL463_RS05245	COG1253	flavin adenine dinucleotide binding
AL463_RS05255	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AL463_RS05270	COG1733	regulation of RNA biosynthetic process
AL463_RS05275	COG0702	epimerase
AL463_RS05280	COG0697	spore germination
AL463_RS05290	COG1113	amino acid transport
AL463_RS05295	COG0545	Peptidyl-prolyl cis-trans isomerase
AL463_RS05300	COG3061	Opacity-associated protein A
AL463_RS05315	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AL463_RS05380	COG1073	alpha beta
AL463_RS05385	COG3650	response to hydrogen peroxide
AL463_RS05395	COG1960	acyl-CoA dehydrogenase activity
AL463_RS05400	COG0754	glutathionylspermidine amidase activity
AL463_RS05405	COG5463	Belongs to the UPF0441 family
AL463_RS05410	COG3766	membrane
AL463_RS05425	COG1842	Phage shock protein A
AL463_RS05430	COG3789	protein conserved in bacteria
AL463_RS05440	COG0557	exoribonuclease II activity
AL463_RS05455	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AL463_RS05460	COG0330	HflC and HflK could
AL463_RS05465	COG0330	HflC and HflK could
AL463_RS05470	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AL463_RS05495	COG0802	atpase or kinase
AL463_RS05500	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AL463_RS05500	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AL463_RS05525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL463_RS05545	COG3264	Mechanosensitive ion channel
AL463_RS05545	COG1511	domain protein
AL463_RS05565	COG1053	succinate dehydrogenase
AL463_RS05570	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AL463_RS05600	COG5510	response to toxic substance
AL463_RS05640	COG0531	amino acid
AL463_RS05645	COG3030	protein affecting phage T7 exclusion by the F plasmid
AL463_RS05655	COG1027	Aspartate ammonia-lyase
AL463_RS05660	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AL463_RS05675	COG1309	transcriptional regulator
AL463_RS05685	COG0789	Transcriptional regulator
AL463_RS05720	COG2197	response regulator
AL463_RS05745	COG3381	protein complex oligomerization
AL463_RS05750	COG3302	dmso reductase anchor subunit
AL463_RS05755	COG0437	4 iron, 4 sulfur cluster binding
AL463_RS05760	COG0243	molybdopterin cofactor binding
AL463_RS05765	COG3290	protein histidine kinase activity
AL463_RS05770	COG4565	transcriptional regulatory protein
AL463_RS05780	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AL463_RS05785	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AL463_RS05785	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AL463_RS05800	COG2169	Transcriptional regulator
AL463_RS05805	COG1982	Orn Lys Arg decarboxylase major
AL463_RS05810	COG2207	Transcriptional regulator
AL463_RS05815	COG0531	amino acid
AL463_RS05840	COG2824	Alkylphosphonate utilization operon protein PhnA
AL463_RS05845	COG2764	glyoxalase bleomycin resistance protein dioxygenase
AL463_RS05860	COG3383	formate dehydrogenase (NAD+) activity
AL463_RS05865	COG3383	formate dehydrogenase (NAD+) activity
AL463_RS05870	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AL463_RS05875	COG1301	dicarboxylic acid transport
AL463_RS05880	COG4235	cytochrome complex assembly
AL463_RS05885	COG1138	Cytochrome C-type biogenesis protein
AL463_RS05890	COG3301	Polysulphide reductase, NrfD
AL463_RS05895	COG0437	4 iron, 4 sulfur cluster binding
AL463_RS05900	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
AL463_RS05920	COG3162	membrane
AL463_RS05930	COG1346	cytolysis
AL463_RS05935	COG1380	Effector of murein hydrolase LrgA
AL463_RS05940	COG0583	DNA-binding transcription factor activity
AL463_RS05945	COG0025	NhaP-type Na H and K H
AL463_RS05950	COG2252	PERMEase
AL463_RS05970	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AL463_RS06035	COG2315	Protein conserved in bacteria
AL463_RS06085	COG0735	belongs to the Fur family
AL463_RS06100	COG0534	Mate efflux family protein
AL463_RS06110	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AL463_RS06165	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL463_RS06190	COG0527	aspartate kinase activity
AL463_RS06265	COG2246	polysaccharide biosynthetic process
AL463_RS06295	COG5301	cellulose 1,4-beta-cellobiosidase activity
AL463_RS06335	COG3122	Protein conserved in bacteria
AL463_RS06380	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AL463_RS06490	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AL463_RS06495	COG2104	thiamine diphosphate biosynthetic process
AL463_RS06560	COG0250	Participates in transcription elongation, termination and antitermination
AL463_RS06670	COG0583	DNA-binding transcription factor activity
AL463_RS06705	COG2207	Transcriptional regulator
AL463_RS06710	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL463_RS06715	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AL463_RS06720	COG1882	Formate acetyltransferase
AL463_RS06725	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL463_RS06730	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL463_RS06735	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL463_RS06735	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AL463_RS06735	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL463_RS06745	COG0371	Dehydrogenase
AL463_RS06750	COG3738	Protein conserved in bacteria
AL463_RS06765	COG0737	Belongs to the 5'-nucleotidase family
AL463_RS06780	COG0668	transmembrane transport
AL463_RS06785	COG0460	homoserine dehydrogenase
AL463_RS06785	COG0527	aspartate kinase activity
AL463_RS06790	COG0626	cystathionine gamma-synthase activity
AL463_RS06815	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AL463_RS06820	COG1609	Transcriptional regulator
AL463_RS06825	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AL463_RS06840	COG1575	Belongs to the MenA family. Type 1 subfamily
AL463_RS06855	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AL463_RS06865	COG1494	fructose-1,6-bisphosphatase
AL463_RS06875	COG3152	Membrane
AL463_RS06945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL463_RS06960	COG2211	Major facilitator Superfamily
AL463_RS06985	COG3678	ATP-independent chaperone mediated protein folding
AL463_RS06990	COG0745	RESPONSE REGULATOR receiver
AL463_RS06995	COG2205	protein histidine kinase activity
AL463_RS07005	COG2258	MOSC domain
AL463_RS07020	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AL463_RS07070	COG1454	alcohol dehydrogenase
AL463_RS07085	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AL463_RS07110	COG0243	molybdopterin cofactor binding
AL463_RS07110	COG3383	formate dehydrogenase (NAD+) activity
AL463_RS07115	COG0243	molybdopterin cofactor binding
AL463_RS07115	COG3383	formate dehydrogenase (NAD+) activity
AL463_RS07120	COG0437	4 iron, 4 sulfur cluster binding
AL463_RS07125	COG2864	formate dehydrogenase
AL463_RS07140	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
AL463_RS07150	COG4680	protein conserved in bacteria
AL463_RS07155	COG5499	transcription regulator containing HTH domain
AL463_RS07160	COG0456	acetyltransferase
AL463_RS07175	COG1011	Hydrolase
AL463_RS07180	COG1349	DNA-binding transcription factor activity
AL463_RS07185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL463_RS07205	COG2017	converts alpha-aldose to the beta-anomer
AL463_RS07210	COG1501	Belongs to the glycosyl hydrolase 31 family
AL463_RS07255	COG0561	phosphatase activity
AL463_RS07310	COG0204	Acyl-transferase
AL463_RS07325	COG3084	Protein conserved in bacteria
AL463_RS07335	COG1763	Mo-molybdopterin cofactor biosynthetic process
AL463_RS07380	COG1739	Uncharacterized protein family UPF0029
AL463_RS07425	COG0805	protein transport
AL463_RS07470	COG0641	radical SAM
AL463_RS07490	COG0561	phosphatase activity
AL463_RS07495	COG2267	carboxylic ester hydrolase activity
AL463_RS07550	COG1011	Hydrolase
AL463_RS07615	COG2959	enzyme of heme biosynthesis
AL463_RS07620	COG3071	HemY protein
AL463_RS07665	COG2244	polysaccharide biosynthetic process
AL463_RS07670	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AL463_RS07675	COG0456	acetyltransferase
AL463_RS07680	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AL463_RS07680	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AL463_RS07685	COG1088	dTDP-glucose 4,6-dehydratase activity
AL463_RS07715	COG3118	belongs to the thioredoxin family
AL463_RS07780	COG3978	acetolactate synthase activity
AL463_RS07840	COG2186	Transcriptional regulator
AL463_RS07845	COG0477	Major facilitator Superfamily
AL463_RS07850	COG1609	Transcriptional regulator
AL463_RS07855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL463_RS07865	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL463_RS07900	COG1522	sequence-specific DNA binding
AL463_RS07905	COG0716	FMN binding
AL463_RS07920	COG3312	ion transport
AL463_RS07980	COG4533	DNA binding
AL463_RS07985	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AL463_RS07990	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL463_RS07990	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL463_RS07990	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AL463_RS07995	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AL463_RS08000	COG0573	inorganic phosphate transmembrane transporter activity
AL463_RS08005	COG0581	inorganic phosphate transmembrane transporter activity
AL463_RS08015	COG0704	Plays a role in the regulation of phosphate uptake
AL463_RS08020	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL463_RS08025	COG2252	PERMEase
AL463_RS08030	COG0431	NADPH-dependent FMN reductase
AL463_RS08035	COG2091	lysine biosynthetic process via aminoadipic acid
AL463_RS08060	COG0582	viral genome integration into host DNA
AL463_RS08065	COG0582	viral genome integration into host DNA
AL463_RS08120	COG4948	Mandelate Racemase Muconate Lactonizing
AL463_RS08125	COG2271	Major facilitator Superfamily
AL463_RS08130	COG0561	phosphatase activity
AL463_RS08135	COG2186	Transcriptional regulator
AL463_RS08140	COG3734	2-keto-3-deoxy-galactonokinase
AL463_RS08145	COG0800	Aldolase
AL463_RS08155	COG2271	Major facilitator Superfamily
AL463_RS08160	COG0784	Response regulator, receiver
AL463_RS08160	COG2198	Histidine kinase
AL463_RS08160	COG2205	protein histidine kinase activity
AL463_RS08165	COG1879	ABC-type sugar transport system periplasmic component
AL463_RS08170	COG0745	RESPONSE REGULATOR receiver
AL463_RS08175	COG3005	denitrification pathway
AL463_RS08190	COG1858	cytochrome C peroxidase
AL463_RS08200	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL463_RS08205	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL463_RS08210	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL463_RS08220	COG1138	Cytochrome C-type biogenesis protein
AL463_RS08230	COG4235	cytochrome complex assembly
AL463_RS08230	COG3088	subunit of a heme lyase
AL463_RS08240	COG5645	(Lipo)protein
AL463_RS08260	COG2149	membrane
AL463_RS08270	COG0641	radical SAM
AL463_RS08280	COG2610	gluconate transmembrane transporter activity
AL463_RS08285	COG0583	DNA-binding transcription factor activity
AL463_RS08295	COG2814	Major facilitator Superfamily
AL463_RS08315	COG0028	Belongs to the TPP enzyme family
AL463_RS08320	COG0440	acetolactate synthase activity
AL463_RS08325	COG1349	DNA-binding transcription factor activity
AL463_RS08335	COG0738	Major facilitator superfamily
AL463_RS08370	COG2188	Transcriptional regulator
AL463_RS08375	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL463_RS08375	COG3711	transcriptional antiterminator
AL463_RS08380	COG3414	Phosphotransferase system galactitol-specific IIB component
AL463_RS08385	COG3775	system Galactitol-specific IIC component
AL463_RS08420	COG2723	6-phospho-beta-galactosidase activity
AL463_RS08440	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL463_RS08440	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL463_RS08445	COG3715	PTS system
AL463_RS08450	COG3716	PTS system mannose fructose sorbose family IID component
AL463_RS08465	COG5464	transposase or invertase
AL463_RS08490	COG1335	isochorismatase
AL463_RS08495	COG3710	Transcriptional regulator
AL463_RS08510	COG2771	luxR family
AL463_RS08525	COG0419	ATPase involved in DNA repair
AL463_RS08540	COG2211	Major facilitator Superfamily
AL463_RS08545	COG1501	Belongs to the glycosyl hydrolase 31 family
AL463_RS08550	COG2982	Protein involved in outer membrane biogenesis
AL463_RS08555	COG2233	PERMEase
AL463_RS08570	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AL463_RS08575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL463_RS08580	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AL463_RS08600	COG2860	membrane
AL463_RS08610	COG0583	DNA-binding transcription factor activity
AL463_RS08615	COG1561	YicC-like family, N-terminal region
AL463_RS08640	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AL463_RS08670	COG1519	Transferase
AL463_RS08675	COG0859	PFAM glycosyl transferase family 9
AL463_RS08680	COG0438	transferase activity, transferring glycosyl groups
AL463_RS08755	COG1216	Glycosyl transferase, family 2
AL463_RS08760	COG2861	carbohydrate metabolic process
AL463_RS08765	COG4942	peptidase
AL463_RS08775	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL463_RS08780	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AL463_RS08800	COG2271	Major facilitator Superfamily
AL463_RS08810	COG1609	Transcriptional regulator
AL463_RS08815	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AL463_RS08825	COG2186	Transcriptional regulator
AL463_RS08855	COG3722	fumarate hydratase activity
AL463_RS08865	COG2213	PTS system mannitol-specific
AL463_RS08865	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL463_RS08870	COG0625	glutathione transferase activity
AL463_RS08880	COG3276	selenocysteine insertion sequence binding
AL463_RS08885	COG1940	carbohydrate kinase activity
AL463_RS08890	COG1012	belongs to the aldehyde dehydrogenase family
AL463_RS08905	COG0235	Class ii aldolase
AL463_RS08910	COG3623	hexulose-6-phosphate isomerase
AL463_RS08915	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AL463_RS08920	COG1070	Carbohydrate kinase
AL463_RS08925	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL463_RS08930	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AL463_RS08935	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AL463_RS08945	COG2731	YhcH YjgK YiaL family protein
AL463_RS08955	COG1414	Transcriptional regulator
AL463_RS08960	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL463_RS08965	COG3977	Valine--pyruvate aminotransferase
AL463_RS08970	COG0366	Alpha amylase catalytic
AL463_RS08980	COG2992	FlgJ-related protein
AL463_RS08985	COG1609	Transcriptional regulator
AL463_RS08985	COG2207	Transcriptional regulator
AL463_RS08995	COG1070	Carbohydrate kinase
AL463_RS09000	COG4682	membrane
AL463_RS09005	COG3274	enterobacterial common antigen metabolic process
AL463_RS09045	COG1278	Cold shock
AL463_RS09050	COG2944	sequence-specific DNA binding
AL463_RS09065	COG2885	chlorophyll binding
AL463_RS09070	COG0243	molybdopterin cofactor binding
AL463_RS09075	COG0456	acetyltransferase
AL463_RS09080	COG2818	Glycosylase
AL463_RS09085	COG5571	outer membrane autotransporter
AL463_RS09145	COG0747	negative chemotaxis
AL463_RS09150	COG0601	transmembrane transport
AL463_RS09155	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL463_RS09160	COG0444	Belongs to the ABC transporter superfamily
AL463_RS09165	COG4608	Belongs to the ABC transporter superfamily
AL463_RS09170	COG0814	amino acid
AL463_RS09175	COG2873	o-acetylhomoserine
AL463_RS09230	COG2200	EAL domain
AL463_RS09230	COG2199	diguanylate cyclase activity
AL463_RS09245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL463_RS09250	COG2200	EAL domain
AL463_RS09255	COG2982	Protein involved in outer membrane biogenesis
AL463_RS09260	COG0477	Major facilitator Superfamily
AL463_RS09265	COG1295	ribonuclease BN
AL463_RS09270	COG0583	DNA-binding transcription factor activity
AL463_RS09275	COG2197	response regulator
AL463_RS09295	COG2188	Transcriptional regulator
AL463_RS09300	COG2222	sugar isomerase
AL463_RS09305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL463_RS09310	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AL463_RS09320	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL463_RS09325	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AL463_RS09330	COG0671	phosphoesterase, PA-phosphatase related
AL463_RS09360	COG0306	phosphate transporter
AL463_RS09365	COG2081	HI0933 family
AL463_RS09370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL463_RS09375	COG0842	Transport permease protein
AL463_RS09375	COG1129	ABC transporter
AL463_RS09380	COG0842	Transport permease protein
AL463_RS09395	COG0628	permease
AL463_RS09410	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AL463_RS09430	COG3714	YhhN family
AL463_RS09440	COG3776	membrane
AL463_RS09445	COG0742	ribosomal rna small subunit methyltransferase
AL463_RS09450	COG0552	protein localization to endoplasmic reticulum
AL463_RS09455	COG2884	Cell division ATP-binding protein ftsE
AL463_RS09460	COG2177	Part of the ABC transporter FtsEX involved in
AL463_RS09540	COG0584	glycerophosphoryl diester phosphodiesterase
AL463_RS09550	COG0405	Gamma-glutamyltransferase
AL463_RS09555	COG1735	metal-dependent hydrolase with the TIM-barrel fold
AL463_RS09570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL463_RS09575	COG1247	-acetyltransferase
AL463_RS09580	COG0673	inositol 2-dehydrogenase activity
AL463_RS09585	COG1741	Belongs to the pirin family
AL463_RS09590	COG1609	Transcriptional regulator
AL463_RS09595	COG3265	gluconokinase activity
AL463_RS09600	COG2610	gluconate transmembrane transporter activity
AL463_RS09630	COG0058	SHG alpha-glucan phosphorylase activity
AL463_RS09635	COG1414	Transcriptional regulator
AL463_RS09640	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL463_RS09645	COG0129	dihydroxy-acid dehydratase activity
AL463_RS09655	COG0371	Dehydrogenase
AL463_RS09670	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AL463_RS09685	COG1349	DNA-binding transcription factor activity
AL463_RS09690	COG4650	regulator
AL463_RS09705	COG1690	Belongs to the RtcB family
AL463_RS09715	COG3077	Addiction module antitoxin, RelB DinJ family
AL463_RS09720	COG3041	Addiction module toxin RelE StbE family
AL463_RS09730	COG0058	SHG alpha-glucan phosphorylase activity
AL463_RS09735	COG1640	4-alpha-glucanotransferase
AL463_RS09740	COG2610	gluconate transmembrane transporter activity
AL463_RS09760	COG5464	transposase or invertase
AL463_RS09775	COG1918	ferrous iron import across plasma membrane
AL463_RS09780	COG2183	response to ionizing radiation
AL463_RS09805	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AL463_RS09815	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AL463_RS09820	COG1011	Hydrolase
AL463_RS09830	COG0494	nUDIX hydrolase
AL463_RS09835	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AL463_RS09840	COG4972	Pilus assembly protein
AL463_RS09845	COG3166	PFAM Fimbrial assembly family protein
AL463_RS09860	COG4796	Type ii and iii secretion system protein
AL463_RS09875	COG3266	domain, Protein
AL463_RS09880	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AL463_RS09885	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AL463_RS09930	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL463_RS09965	COG1289	transmembrane transporter activity
AL463_RS09975	COG1765	OsmC-like protein
AL463_RS09980	COG3954	Phosphoribulokinase
AL463_RS09990	COG0429	hydrolase of the alpha beta-hydrolase fold
AL463_RS10005	COG0488	(ABC) transporter
AL463_RS10020	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AL463_RS10025	COG1047	Peptidyl-prolyl cis-trans
AL463_RS10035	COG0545	Peptidyl-prolyl cis-trans isomerase
AL463_RS10040	COG2964	Protein conserved in bacteria
AL463_RS10095	COG0051	transcription antitermination factor activity, RNA binding
AL463_RS10120	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AL463_RS10200	COG0201	protein transport
AL463_RS10240	COG0789	Transcriptional regulator
AL463_RS10245	COG3036	rescue of stalled ribosome
AL463_RS10275	COG0758	DNA mediated transformation
AL463_RS10285	COG0551	DNA topoisomerase type I activity
AL463_RS10305	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AL463_RS10350	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL463_RS10355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL463_RS10360	COG1309	transcriptional regulator
AL463_RS10375	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AL463_RS10395	COG4145	pantothenate transmembrane transporter activity
AL463_RS10400	COG3924	membrane
AL463_RS10405	COG0439	Biotin carboxylase
AL463_RS10410	COG0511	ligase activity, forming carbon-carbon bonds
AL463_RS10425	COG0604	alcohol dehydrogenase
AL463_RS10430	COG2199	diguanylate cyclase activity
AL463_RS10430	COG2200	EAL domain
AL463_RS10440	COG1077	Cell shape determining protein MreB Mrl
AL463_RS10445	COG1792	Involved in formation and maintenance of cell shape
AL463_RS10450	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AL463_RS10465	COG3164	Protein of unknown function
AL463_RS10470	COG0312	modulator of DNA gyrase
AL463_RS10475	COG0583	DNA-binding transcription factor activity
AL463_RS10495	COG2732	(Barnase) inhibitor
AL463_RS10520	COG2188	Transcriptional regulator
AL463_RS10530	COG0471	metal ion transport
AL463_RS10535	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AL463_RS10540	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AL463_RS10560	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
AL463_RS10570	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL463_RS10575	COG3105	Protein conserved in bacteria
AL463_RS10580	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AL463_RS10600	COG0625	glutathione transferase activity
AL463_RS10605	COG2969	positive regulation of protein catabolic process
AL463_RS10635	COG2731	YhcH YjgK YiaL family protein
AL463_RS10640	COG0402	S-adenosylhomocysteine deaminase activity
AL463_RS10645	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AL463_RS10650	COG4804	nuclease activity
AL463_RS10655	COG0493	'glutamate synthase
AL463_RS10660	COG0070	glutamate synthase
AL463_RS10660	COG0067	glutamate synthase
AL463_RS10660	COG0069	glutamate synthase activity
AL463_RS10670	COG1242	4 iron, 4 sulfur cluster binding
AL463_RS10675	COG5002	protein histidine kinase activity
AL463_RS10675	COG2198	Histidine kinase
AL463_RS10675	COG0784	Response regulator, receiver
AL463_RS10680	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AL463_RS10690	COG0515	serine threonine protein kinase
AL463_RS10695	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL463_RS10720	COG1137	ATPase activity
AL463_RS10725	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AL463_RS10730	COG3117	lipopolysaccharide transmembrane transporter activity
AL463_RS10745	COG0530	calcium, potassium:sodium antiporter activity
AL463_RS10750	COG1127	ABC transporter
AL463_RS10755	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AL463_RS10760	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AL463_RS10765	COG2854	intermembrane phospholipid transfer
AL463_RS10770	COG3113	response to antibiotic
AL463_RS10775	COG5007	Belongs to the BolA IbaG family
AL463_RS10785	COG3423	Transcriptional regulator
AL463_RS10790	COG0142	geranyltranstransferase activity
AL463_RS10815	COG2027	D-alanyl-D-alanine carboxypeptidase
AL463_RS10830	COG1534	Rna-binding protein
AL463_RS10845	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AL463_RS10855	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AL463_RS10920	COG0513	Belongs to the DEAD box helicase family
AL463_RS10925	COG0814	amino acid
AL463_RS10935	COG3034	peptidoglycan biosynthetic process
AL463_RS10940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL463_RS10945	COG0826	peptidase U32
AL463_RS10950	COG0826	peptidase U32
AL463_RS10955	COG3154	lipid carrier protein
AL463_RS10960	COG3153	acetyltransferase
AL463_RS10975	COG0693	protein deglycase activity
AL463_RS10980	COG0702	epimerase
AL463_RS10985	COG2823	Periplasmic or secreted lipoprotein
AL463_RS11005	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AL463_RS11015	COG1063	alcohol dehydrogenase
AL463_RS11020	COG3775	system Galactitol-specific IIC component
AL463_RS11025	COG3414	Phosphotransferase system galactitol-specific IIB component
AL463_RS11030	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL463_RS11045	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL463_RS11045	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL463_RS11045	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL463_RS11050	COG1105	Belongs to the carbohydrate kinase PfkB family
AL463_RS11060	COG1349	DNA-binding transcription factor activity
AL463_RS11065	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL463_RS11070	COG2721	sulfolactate sulfo-lyase activity
AL463_RS11080	COG2084	Dehydrogenase
AL463_RS11085	COG1929	Belongs to the glycerate kinase type-1 family
AL463_RS11095	COG0583	DNA-binding transcription factor activity
AL463_RS11115	COG1882	Formate acetyltransferase
AL463_RS11120	COG1760	l-serine dehydratase
AL463_RS11125	COG0814	amino acid
AL463_RS11140	COG1741	Belongs to the pirin family
AL463_RS11145	COG0583	DNA-binding transcription factor activity
AL463_RS11150	COG3152	Membrane
AL463_RS11155	COG0435	Glutathione S-transferase
AL463_RS11160	COG2259	Doxx family
AL463_RS11170	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
AL463_RS11175	COG4575	ribosome binding
AL463_RS11180	COG1422	Protein of unknown function (DUF1090)
AL463_RS11190	COG0586	Pfam SNARE associated Golgi protein
AL463_RS11205	COG0673	inositol 2-dehydrogenase activity
AL463_RS11210	COG2949	membrane
AL463_RS11215	COG1451	nucleotide metabolic process
AL463_RS11225	COG0446	pyridine nucleotide-disulphide oxidoreductase
AL463_RS11225	COG1902	pentaerythritol trinitrate reductase activity
AL463_RS11235	COG0840	transmembrane signaling receptor activity
AL463_RS11240	COG0840	transmembrane signaling receptor activity
AL463_RS11245	COG1695	Transcriptional regulator
AL463_RS11250	COG2375	cellular response to nickel ion
AL463_RS11275	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AL463_RS11290	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AL463_RS11305	COG4991	sh3 domain protein
AL463_RS11310	COG3025	triphosphatase activity
AL463_RS11325	COG2268	Band 7 protein
AL463_RS11330	COG1585	Membrane protein implicated in regulation of membrane protease activity
AL463_RS11375	COG3384	dioxygenase
AL463_RS11380	COG0754	glutathionylspermidine amidase activity
AL463_RS11395	COG0494	nUDIX hydrolase
AL463_RS11400	COG3151	Protein conserved in bacteria
AL463_RS11405	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AL463_RS11410	COG3150	esterase
AL463_RS11420	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AL463_RS11425	COG2249	NAD(P)H dehydrogenase (quinone) activity
AL463_RS11440	COG3111	PFAM Bacterial OB fold (BOF) protein
AL463_RS11445	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AL463_RS11495	COG0471	metal ion transport
AL463_RS11505	COG1979	alcohol dehydrogenase
AL463_RS11510	COG2207	Transcriptional regulator
AL463_RS11535	COG0848	biopolymer transport protein
AL463_RS11540	COG1028	Short-chain dehydrogenase reductase Sdr
AL463_RS11565	COG0840	transmembrane signaling receptor activity
AL463_RS11575	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AL463_RS11580	COG0437	4 iron, 4 sulfur cluster binding
AL463_RS11585	COG5557	Pfam Polysulphide reductase, NrfD
AL463_RS11590	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AL463_RS11595	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AL463_RS11600	COG1773	rubredoxin
AL463_RS11610	COG0298	carbon dioxide binding
AL463_RS11615	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL463_RS11625	COG0625	glutathione transferase activity
AL463_RS11645	COG0246	Mannitol dehydrogenase
AL463_RS11655	COG2271	Major facilitator Superfamily
AL463_RS11680	COG1012	belongs to the aldehyde dehydrogenase family
AL463_RS11685	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL463_RS11695	COG0531	amino acid
AL463_RS11725	COG2301	Belongs to the HpcH HpaI aldolase family
AL463_RS11730	COG2030	dehydratase
AL463_RS11735	COG0427	acetyl-CoA hydrolase
AL463_RS11750	COG1811	Na channel or pump
AL463_RS11760	COG1982	Orn Lys Arg decarboxylase major
AL463_RS11765	COG2211	Major facilitator Superfamily
AL463_RS11790	COG3171	Protein conserved in bacteria
AL463_RS11800	COG0252	asparaginase activity
AL463_RS11810	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AL463_RS11825	COG0762	integral membrane protein
AL463_RS11830	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AL463_RS11835	COG2805	Type II/IV secretion system protein
AL463_RS11860	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AL463_RS11865	COG2356	endonuclease I
AL463_RS11875	COG2814	Major facilitator Superfamily
AL463_RS11895	COG1166	arginine decarboxylase activity
AL463_RS11905	COG2186	Transcriptional regulator
AL463_RS11910	COG4948	Mandelate Racemase Muconate Lactonizing
AL463_RS11915	COG0246	Mannitol dehydrogenase
AL463_RS11920	COG1063	alcohol dehydrogenase
AL463_RS11925	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AL463_RS11930	COG2731	YhcH YjgK YiaL family protein
AL463_RS11935	COG2267	carboxylic ester hydrolase activity
AL463_RS11945	COG0501	Belongs to the peptidase M48B family
AL463_RS11950	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AL463_RS11955	COG1122	ATPase activity
AL463_RS11960	COG1122	ATPase activity
AL463_RS11990	COG0191	fructose-bisphosphate aldolase activity
AL463_RS11995	COG0668	transmembrane transport
AL463_RS12005	COG2968	Membrane
AL463_RS12025	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL463_RS12030	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AL463_RS12050	COG0006	proline dipeptidase activity
AL463_RS12055	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL463_RS12060	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL463_RS12085	COG2723	6-phospho-beta-galactosidase activity
AL463_RS12095	COG1272	protein, Hemolysin III
AL463_RS12155	COG4942	peptidase
AL463_RS12205	COG3188	usher protein
AL463_RS12240	COG0814	amino acid
AL463_RS12255	COG0183	Belongs to the thiolase family
AL463_RS12265	COG1028	Short-chain dehydrogenase reductase Sdr
AL463_RS12270	COG2814	Major facilitator Superfamily
AL463_RS12275	COG1794	racemase activity, acting on amino acids and derivatives
AL463_RS12280	COG0583	DNA-binding transcription factor activity
AL463_RS12290	COG1609	Transcriptional regulator
AL463_RS12310	COG0667	Aldo Keto reductase
AL463_RS12320	COG0861	Integral membrane protein TerC family
AL463_RS12355	COG2165	general secretion pathway protein
AL463_RS12360	COG4795	General secretion pathway protein
AL463_RS12370	COG4967	type IV pilus modification protein PilV
AL463_RS12375	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AL463_RS12385	COG1074	ATP-dependent DNA helicase activity
AL463_RS12390	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AL463_RS12400	COG0860	N-Acetylmuramoyl-L-alanine amidase
AL463_RS12415	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AL463_RS12420	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AL463_RS12425	COG2962	Rard protein
AL463_RS12430	COG2166	iron-sulfur cluster assembly
AL463_RS12435	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AL463_RS12445	COG0583	DNA-binding transcription factor activity
AL463_RS12450	COG2363	Small membrane protein
AL463_RS12460	COG1349	DNA-binding transcription factor activity
AL463_RS12480	COG0738	Major facilitator superfamily
AL463_RS12485	COG0235	Class ii aldolase
AL463_RS12490	COG1454	alcohol dehydrogenase
AL463_RS12500	COG1760	l-serine dehydratase
AL463_RS12505	COG0814	amino acid
AL463_RS12510	COG1611	Belongs to the LOG family
AL463_RS12530	COG3098	single-species biofilm formation
AL463_RS12540	COG0716	FMN binding
AL463_RS12545	COG2271	Major facilitator Superfamily
AL463_RS12550	COG4948	Mandelate Racemase Muconate Lactonizing
AL463_RS12555	COG4948	Mandelate Racemase Muconate Lactonizing
AL463_RS12560	COG1929	Belongs to the glycerate kinase type-1 family
AL463_RS12565	COG2205	protein histidine kinase activity
AL463_RS12565	COG3437	response regulator, receiver
AL463_RS12565	COG3850	Histidine kinase
AL463_RS12565	COG4999	Histidine kinase
AL463_RS12575	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AL463_RS12580	COG3609	addiction module antidote protein, CC2985 family
AL463_RS12590	COG3956	TIGRFAM MazG family protein
AL463_RS12605	COG0602	queuosine metabolic process
AL463_RS12610	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AL463_RS12610	COG0321	lipoyl(octanoyl) transferase activity
AL463_RS12615	COG0720	synthase
AL463_RS12640	COG1203	CRISPR-associated helicase, Cas3
AL463_RS12655	COG1857	crispr-associated protein
AL463_RS12670	COG1518	maintenance of DNA repeat elements
AL463_RS12675	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AL463_RS12680	COG2234	aminopeptidase activity
AL463_RS12750	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AL463_RS12755	COG0163	prenyltransferase activity
AL463_RS12765	COG1349	DNA-binding transcription factor activity
AL463_RS12770	COG2084	Dehydrogenase
AL463_RS12780	COG0235	Class ii aldolase
AL463_RS12785	COG3622	Belongs to the hyi family
AL463_RS12790	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL463_RS12795	COG2610	gluconate transmembrane transporter activity
AL463_RS12805	COG0477	Major facilitator Superfamily
AL463_RS12865	COG2207	Transcriptional regulator
AL463_RS13040	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AL463_RS13045	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AL463_RS13050	COG1121	(ABC) transporter
AL463_RS13070	COG0309	Hydrogenase expression formation protein (HypE)
AL463_RS13075	COG0409	Hydrogenase expression formation protein
AL463_RS13080	COG0298	carbon dioxide binding
AL463_RS13085	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AL463_RS13100	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL463_RS13105	COG0651	ATP synthesis coupled electron transport
AL463_RS13110	COG0650	Formate hydrogenlyase subunit 4
AL463_RS13115	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
AL463_RS13115	COG3261	NADH dehydrogenase
AL463_RS13120	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL463_RS13125	COG3260	NADH ubiquinone oxidoreductase 20
AL463_RS13135	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AL463_RS13145	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL463_RS13150	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AL463_RS13175	COG1349	DNA-binding transcription factor activity
AL463_RS13185	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL463_RS13190	COG1028	Short-chain dehydrogenase reductase Sdr
AL463_RS13200	COG3732	PTS system glucitol sorbitol-specific
AL463_RS13205	COG3730	PTS system glucitol sorbitol-specific
AL463_RS13210	COG2951	lytic endotransglycosylase activity
AL463_RS13215	COG1546	Belongs to the CinA family
AL463_RS13235	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AL463_RS13265	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL463_RS13270	COG1238	metal cluster binding
AL463_RS13290	COG2814	Major facilitator Superfamily
AL463_RS13295	COG1566	PFAM secretion protein HlyD family protein
AL463_RS13300	COG1846	Transcriptional regulator
AL463_RS13305	COG2814	Major facilitator Superfamily
AL463_RS13350	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL463_RS13360	COG4575	ribosome binding
AL463_RS13385	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL463_RS13390	COG0640	Transcriptional regulator
AL463_RS13395	COG0401	homolog of Blt101
AL463_RS13400	COG1652	LysM domain
AL463_RS13405	COG1802	Transcriptional regulator
AL463_RS13410	COG1113	amino acid transport
AL463_RS13415	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL463_RS13420	COG1012	belongs to the aldehyde dehydrogenase family
AL463_RS13425	COG0579	oxidoreductase
AL463_RS13465	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
AL463_RS13480	COG2990	Protein conserved in bacteria
AL463_RS13500	COG2819	hydrolase of the alpha beta superfamily
AL463_RS13535	COG2801	Transposase and inactivated derivatives
AL463_RS13555	COG2963	transposase activity
AL463_RS13565	COG2801	Transposase and inactivated derivatives
AL463_RS13600	COG1263	PTS System
AL463_RS13600	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL463_RS13600	COG2190	(PTS) system
AL463_RS13610	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AL463_RS13615	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AL463_RS13625	COG0673	inositol 2-dehydrogenase activity
AL463_RS13645	COG3423	Transcriptional regulator
AL463_RS13660	COG4133	protoheme IX ABC transporter activity
AL463_RS13690	COG0582	viral genome integration into host DNA
AL463_RS13695	COG0582	viral genome integration into host DNA
AL463_RS13700	COG4974	Belongs to the 'phage' integrase family
AL463_RS13740	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AL463_RS13780	COG4695	Portal protein
AL463_RS13885	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AL463_RS13935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL463_RS13960	COG2867	negative regulation of translational initiation
AL463_RS13975	COG0497	DNA recombination
AL463_RS13995	COG4536	flavin adenine dinucleotide binding
AL463_RS14000	COG4137	Cytochrome C assembly protein
AL463_RS14005	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AL463_RS14030	COG2199	diguanylate cyclase activity
AL463_RS14045	COG0287	Prephenate dehydrogenase
AL463_RS14045	COG1605	Chorismate mutase
AL463_RS14055	COG0077	Prephenate dehydratase
AL463_RS14055	COG1605	Chorismate mutase
AL463_RS14060	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AL463_RS14065	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL463_RS14080	COG0542	response to heat
AL463_RS14110	COG0477	Major facilitator Superfamily
AL463_RS14115	COG5544	Lipoprotein
AL463_RS14120	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL463_RS14130	COG3148	PFAM DTW domain containing protein
AL463_RS14135	COG3118	belongs to the thioredoxin family
AL463_RS14140	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL463_RS14160	COG0583	DNA-binding transcription factor activity
AL463_RS14165	COG0513	Belongs to the DEAD box helicase family
AL463_RS14195	COG3086	response to oxidative stress
AL463_RS14220	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AL463_RS14255	COG1484	DNA-dependent DNA replication
AL463_RS14350	COG4220	transposase activity
AL463_RS14460	COG5301	cellulose 1,4-beta-cellobiosidase activity
AL463_RS14525	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL463_RS14530	COG0583	DNA-binding transcription factor activity
AL463_RS14535	COG2223	nitrite transmembrane transporter activity
AL463_RS14540	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AL463_RS14545	COG1737	Transcriptional regulator
AL463_RS14555	COG1263	PTS System
AL463_RS14555	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL463_RS14560	COG0560	Phosphoserine phosphatase
AL463_RS14585	COG2205	protein histidine kinase activity
AL463_RS14590	COG3170	Tfp pilus assembly protein FimV
AL463_RS14595	COG2204	response regulator
AL463_RS14600	COG0347	Belongs to the P(II) protein family
AL463_RS14605	COG3104	oligopeptide transport
AL463_RS14615	COG0531	amino acid
AL463_RS14620	COG3710	Transcriptional regulator
AL463_RS14635	COG2814	Major facilitator Superfamily
AL463_RS14640	COG3711	transcriptional antiterminator
AL463_RS14650	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AL463_RS14695	COG0822	iron-sulfur transferase activity
AL463_RS14715	COG0633	Ferredoxin
AL463_RS14720	COG2975	iron-sulfur cluster assembly
AL463_RS14740	COG2897	thiosulfate sulfurtransferase activity
AL463_RS14745	COG2373	Large extracellular alpha-helical protein
AL463_RS14750	COG4953	penicillin-binding protein 1C
AL463_RS14755	COG0243	molybdopterin cofactor binding
AL463_RS14760	COG0437	4 iron, 4 sulfur cluster binding
AL463_RS14800	COG2976	Protein conserved in bacteria
AL463_RS14815	COG1645	bacterial-type flagellum-dependent swarming motility
AL463_RS14850	COG0516	GMP reductase activity
AL463_RS14850	COG0517	IMP dehydrogenase activity
AL463_RS14860	COG2801	Transposase and inactivated derivatives
AL463_RS14880	COG2200	EAL domain
AL463_RS14895	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AL463_RS14910	COG2233	PERMEase
AL463_RS14920	COG1393	Belongs to the ArsC family
AL463_RS14930	COG0628	permease
AL463_RS14935	COG1929	Belongs to the glycerate kinase type-1 family
AL463_RS14940	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AL463_RS14945	COG2716	regulation of RNA biosynthetic process
AL463_RS14955	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AL463_RS14965	COG2321	neutral zinc metallopeptidase
AL463_RS14985	COG1393	Belongs to the ArsC family
AL463_RS14990	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL463_RS14995	COG3850	Histidine kinase
AL463_RS15000	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL463_RS15000	COG0493	'glutamate synthase
AL463_RS15015	COG5342	invasion associated locus B
AL463_RS15025	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AL463_RS15165	COG2837	iron assimilation
AL463_RS15185	COG4208	sulfate ABC transporter
AL463_RS15240	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL463_RS15270	COG3530	Putative quorum-sensing-regulated virulence factor
AL463_RS15275	COG0385	Bile acid
AL463_RS15280	COG0583	DNA-binding transcription factor activity
AL463_RS15290	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AL463_RS15295	COG2211	Major facilitator Superfamily
AL463_RS15305	COG0583	DNA-binding transcription factor activity
AL463_RS15335	COG3415	Transposase
AL463_RS15340	COG3415	Transposase
AL463_RS15355	COG2199	diguanylate cyclase activity
AL463_RS15355	COG2200	EAL domain
AL463_RS15360	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AL463_RS15375	COG0667	Aldo Keto reductase
AL463_RS15380	COG3961	Belongs to the TPP enzyme family
AL463_RS15395	COG0436	Aminotransferase
AL463_RS15400	COG1560	Kdo2-lipid A biosynthetic process
AL463_RS15450	COG2116	formate transmembrane transporter activity
AL463_RS15465	COG3691	Protein conserved in bacteria
AL463_RS15480	COG2062	phosphohistidine phosphatase, SixA
AL463_RS15505	COG0730	response to heat
AL463_RS15510	COG3101	peptidyl-lysine hydroxylation
AL463_RS15525	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL463_RS15545	COG3423	Transcriptional regulator
AL463_RS15570	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AL463_RS15580	COG0586	Pfam SNARE associated Golgi protein
AL463_RS15590	COG0285	dihydrofolate synthase activity
AL463_RS15595	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AL463_RS15600	COG1286	toxin biosynthetic process
AL463_RS15605	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AL463_RS15610	COG3829	transcription factor binding
AL463_RS15620	COG0531	amino acid
AL463_RS15625	COG3457	Alanine racemase
AL463_RS15630	COG0833	amino acid
AL463_RS15665	COG1090	epimerase
AL463_RS15670	COG0625	glutathione transferase activity
AL463_RS15675	COG0625	glutathione transferase activity
AL463_RS15680	COG0622	Phosphoesterase
AL463_RS15690	COG1609	Transcriptional regulator
AL463_RS15700	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL463_RS15710	COG3037	sugar-specific permease SgaT UlaA
AL463_RS15715	COG3959	Transketolase, thiamine diphosphate binding domain
AL463_RS15720	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AL463_RS15725	COG1288	antiporter activity
AL463_RS15750	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL463_RS15755	COG0471	metal ion transport
AL463_RS15755	COG0490	domain, Protein
AL463_RS15765	COG0436	Aminotransferase
AL463_RS15770	COG0583	DNA-binding transcription factor activity
AL463_RS15820	COG0839	Belongs to the complex I subunit 6 family
AL463_RS15830	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AL463_RS15835	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL463_RS15845	COG2304	oxidoreductase activity
AL463_RS15850	COG0835	chemotaxis
AL463_RS15850	COG0784	Response regulator, receiver
AL463_RS15860	COG2153	protein acetylation
AL463_RS15865	COG4575	ribosome binding
AL463_RS15870	COG1169	isochorismate synthase
AL463_RS15960	COG1414	Transcriptional regulator
AL463_RS15970	COG2271	Major facilitator Superfamily
AL463_RS15990	COG0247	lactate metabolic process
AL463_RS16000	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AL463_RS16005	COG2271	Major facilitator Superfamily
AL463_RS16010	COG0584	glycerophosphoryl diester phosphodiesterase
AL463_RS16015	COG0583	DNA-binding transcription factor activity
AL463_RS16020	COG2814	Major facilitator Superfamily
AL463_RS16025	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL463_RS16055	COG4948	Mandelate Racemase Muconate Lactonizing
AL463_RS16075	COG2198	Histidine kinase
AL463_RS16075	COG0642	Histidine kinase
AL463_RS16100	COG4615	Cyclic peptide transporter
AL463_RS16110	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL463_RS16110	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL463_RS16115	COG3062	negative regulation of establishment of protein localization
AL463_RS16125	COG0437	4 iron, 4 sulfur cluster binding
AL463_RS16130	COG0348	domain, Protein
AL463_RS16135	COG3043	anaerobic respiration
AL463_RS16140	COG3005	denitrification pathway
AL463_RS16145	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL463_RS16150	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL463_RS16155	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL463_RS16165	COG1138	Cytochrome C-type biogenesis protein
AL463_RS16175	COG4235	cytochrome complex assembly
AL463_RS16175	COG3088	subunit of a heme lyase
AL463_RS16180	COG2197	response regulator
AL463_RS16195	COG5301	cellulose 1,4-beta-cellobiosidase activity
AL463_RS16215	COG1403	HNH endonuclease
AL463_RS16300	COG1061	Type III restriction enzyme res subunit
AL463_RS16310	COG2814	Major facilitator Superfamily
AL463_RS16325	COG4172	Belongs to the ABC transporter superfamily
AL463_RS16330	COG4239	(ABC) transporter, permease
AL463_RS16335	COG4174	ABC transporter (Permease)
AL463_RS16340	COG4166	transmembrane transport
AL463_RS16345	COG2200	EAL domain
AL463_RS16350	COG0791	NLP P60 protein
AL463_RS16355	COG0671	phosphoesterase, PA-phosphatase related
AL463_RS16360	COG0523	cobalamin synthesis protein
AL463_RS16395	COG1105	Belongs to the carbohydrate kinase PfkB family
AL463_RS16400	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL463_RS16400	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AL463_RS16400	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL463_RS16415	COG0583	DNA-binding transcription factor activity
AL463_RS16420	COG0833	amino acid
AL463_RS16425	COG4771	TonB-dependent receptor
AL463_RS16430	COG2271	Major facilitator Superfamily
AL463_RS16435	COG0560	Phosphoserine phosphatase
AL463_RS16440	COG1760	l-serine dehydratase
AL463_RS16460	COG2311	Membrane
AL463_RS16500	COG2949	membrane
AL463_RS16510	COG1346	cytolysis
AL463_RS16525	COG2271	Major facilitator Superfamily
AL463_RS16540	COG0625	glutathione transferase activity
AL463_RS16545	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL463_RS16555	COG1538	Outer membrane efflux protein
AL463_RS16560	COG1028	Short-chain dehydrogenase reductase Sdr
AL463_RS16565	COG0586	Pfam SNARE associated Golgi protein
AL463_RS16575	COG1686	Belongs to the peptidase S11 family
AL463_RS16580	COG0277	FAD linked oxidase domain protein
AL463_RS16590	COG1732	Glycine betaine
AL463_RS16595	COG1174	glycine betaine transport
AL463_RS16600	COG1125	glycine betaine transport
AL463_RS16605	COG1174	glycine betaine transport
AL463_RS16620	COG3275	phosphorelay sensor kinase activity
AL463_RS16630	COG4807	Protein conserved in bacteria
AL463_RS16640	COG4808	Protein conserved in bacteria
AL463_RS16665	COG3121	Chaperone
AL463_RS16670	COG3188	usher protein
AL463_RS16675	COG3539	Fimbrial protein
AL463_RS16680	COG5455	response to cobalt ion
AL463_RS16695	COG2188	Transcriptional regulator
AL463_RS16700	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL463_RS16705	COG1397	ADP-ribosylglycohydrolase
AL463_RS16710	COG2211	Major facilitator Superfamily
AL463_RS16715	COG1830	Aldolase
AL463_RS16745	COG0826	peptidase U32
AL463_RS16765	COG0745	RESPONSE REGULATOR receiver
AL463_RS16770	COG2205	protein histidine kinase activity
AL463_RS16795	COG0443	Heat shock 70 kDa protein
AL463_RS16800	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AL463_RS16805	COG5002	protein histidine kinase activity
AL463_RS16805	COG5001	Diguanylate cyclase
AL463_RS16805	COG3447	MASE1 domain protein
AL463_RS16820	COG2982	Protein involved in outer membrane biogenesis
AL463_RS16825	COG1253	flavin adenine dinucleotide binding
AL463_RS16845	COG0463	Glycosyl transferase, family 2
AL463_RS16850	COG1045	serine acetyltransferase
AL463_RS16855	COG0438	transferase activity, transferring glycosyl groups
AL463_RS16865	COG1216	Glycosyl transferase, family 2
AL463_RS16870	COG0110	maltose O-acetyltransferase activity
AL463_RS16875	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AL463_RS16880	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL463_RS16890	COG0297	glycogen (starch) synthase activity
AL463_RS16905	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AL463_RS16910	COG2244	polysaccharide biosynthetic process
AL463_RS16915	COG2327	Polysaccharide pyruvyl transferase
AL463_RS17070	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL463_RS17075	COG0583	DNA-binding transcription factor activity
AL463_RS17080	COG0531	amino acid
AL463_RS17085	COG2925	Exonuclease
AL463_RS17120	COG1289	transmembrane transporter activity
AL463_RS17155	COG4656	Part of a membrane complex involved in electron transport
AL463_RS17160	COG1454	alcohol dehydrogenase
AL463_RS17160	COG1012	belongs to the aldehyde dehydrogenase family
AL463_RS17175	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
AL463_RS17190	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AL463_RS17360	COG0534	Mate efflux family protein
AL463_RS17390	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AL463_RS17430	COG0582	viral genome integration into host DNA
AL463_RS17470	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL463_RS17480	COG1418	mRNA catabolic process
AL463_RS17485	COG0270	DNA (cytosine-5-)-methyltransferase activity
AL463_RS17490	COG3727	T/G mismatch-specific endonuclease activity
AL463_RS17495	COG0697	spore germination
AL463_RS17500	COG2354	Protein conserved in bacteria
AL463_RS17505	COG5475	Uncharacterized small protein (DUF2158)
AL463_RS17610	COG0425	Belongs to the sulfur carrier protein TusA family
AL463_RS17670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL463_RS17680	COG0765	amino acid transport
AL463_RS17685	COG1126	abc transporter atp-binding protein
AL463_RS17690	COG2197	response regulator
AL463_RS17705	COG2197	response regulator
AL463_RS17750	COG3318	Belongs to the UPF0149 family
AL463_RS17750	COG3012	SEC-C Motif Domain Protein
AL463_RS17755	COG0814	amino acid
AL463_RS17765	COG1528	Iron-storage protein
AL463_RS17780	COG1528	Iron-storage protein
AL463_RS17880	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AL463_RS17895	COG3102	Protein conserved in bacteria
AL463_RS17915	COG3788	relative of glutathione S-transferase, MAPEG superfamily
AL463_RS17920	COG1801	Protein of unknown function DUF72
AL463_RS17925	COG1335	isochorismatase
AL463_RS17935	COG0494	nUDIX hydrolase
AL463_RS17970	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AL463_RS17980	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AL463_RS17985	COG0739	heme binding
AL463_RS17990	COG1560	Kdo2-lipid A biosynthetic process
AL463_RS18000	COG1737	Transcriptional regulator
AL463_RS18005	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AL463_RS18010	COG0129	dihydroxy-acid dehydratase activity
AL463_RS18015	COG0800	Aldolase
AL463_RS18025	COG3141	response to X-ray
AL463_RS18035	COG2979	Protein of unknown function (DUF533)
AL463_RS18040	COG1770	oligopeptidase
AL463_RS18045	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AL463_RS18050	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL463_RS18060	COG2372	response to copper ion
AL463_RS18065	COG1276	copper resistance
AL463_RS18085	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AL463_RS18155	COG0454	-acetyltransferase
AL463_RS18165	COG5562	phage envelope protein
AL463_RS18200	COG3008	intermembrane lipid transfer
AL463_RS18205	COG2995	paraquat-inducible protein a
AL463_RS18210	COG1956	GAF domain-containing protein
AL463_RS18230	COG2814	Major facilitator Superfamily
AL463_RS18235	COG1414	Transcriptional regulator
AL463_RS18265	COG0768	penicillin binding
AL463_RS18270	COG2226	methyltransferase
AL463_RS18285	COG3716	PTS system mannose fructose sorbose family IID component
AL463_RS18290	COG3715	PTS system
AL463_RS18295	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL463_RS18295	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL463_RS18305	COG1253	flavin adenine dinucleotide binding
AL463_RS18310	COG2200	EAL domain
AL463_RS18315	COG1760	l-serine dehydratase
AL463_RS18335	COG0251	oxidation-reduction process
AL463_RS18340	COG1199	ATP-dependent helicase activity
AL463_RS18350	COG3065	identical protein binding
AL463_RS18360	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AL463_RS18370	COG2894	cell division
AL463_RS18385	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL463_RS18425	COG2719	SpoVR family
AL463_RS18445	COG1619	proteins homologs of microcin C7 resistance protein MccF
AL463_RS18470	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AL463_RS18480	COG1294	oxidase, subunit
AL463_RS18485	COG1271	oxidase subunit
AL463_RS18490	COG1773	rubredoxin
AL463_RS18495	COG1999	signal sequence binding
AL463_RS18500	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AL463_RS18505	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
AL463_RS18515	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AL463_RS18525	COG0012	GTP binding
AL463_RS18540	COG0659	secondary active sulfate transmembrane transporter activity
AL463_RS18590	COG0387	Pfam Sodium calcium exchanger
AL463_RS18595	COG4572	Cation transport regulator
AL463_RS18600	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AL463_RS18605	COG4932	domain protein
AL463_RS18610	COG2197	response regulator
AL463_RS18615	COG3850	Histidine kinase
AL463_RS18625	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AL463_RS18630	COG1140	nitrate reductase beta subunit
AL463_RS18635	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AL463_RS18640	COG2181	nitrate reductase activity
AL463_RS18685	COG0788	formyltetrahydrofolate deformylase activity
AL463_RS18695	COG1752	Esterase of the alpha-beta hydrolase superfamily
AL463_RS18700	COG0745	RESPONSE REGULATOR receiver
AL463_RS18705	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AL463_RS18720	COG1012	belongs to the aldehyde dehydrogenase family
AL463_RS18720	COG1454	alcohol dehydrogenase
AL463_RS18725	COG2095	MarC family integral membrane protein
AL463_RS18755	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL463_RS18770	COG2350	Protein conserved in bacteria
AL463_RS18795	COG0727	PFAM Uncharacterised protein family (UPF0153)
AL463_RS18805	COG3546	catalase activity
AL463_RS18810	COG3685	Protein conserved in bacteria
AL463_RS18815	COG3685	Protein conserved in bacteria
AL463_RS18820	COG3729	General stress protein
AL463_RS18855	COG0009	L-threonylcarbamoyladenylate synthase
AL463_RS18870	COG1028	Short-chain dehydrogenase reductase Sdr
AL463_RS18875	COG0616	signal peptide processing
AL463_RS18910	COG0671	phosphoesterase, PA-phosphatase related
AL463_RS18915	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AL463_RS18920	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AL463_RS18940	COG1349	DNA-binding transcription factor activity
AL463_RS18950	COG5001	Diguanylate cyclase
AL463_RS19015	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AL463_RS19020	COG1842	Phage shock protein A
AL463_RS19030	COG1983	PspC domain protein
AL463_RS19040	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL463_RS19045	COG3106	COG3106 Predicted ATPase
AL463_RS19065	COG4948	Mandelate Racemase Muconate Lactonizing
AL463_RS19070	COG2866	Carboxypeptidase
AL463_RS19075	COG4166	transmembrane transport
AL463_RS19085	COG0583	DNA-binding transcription factor activity
AL463_RS19090	COG0656	L-ascorbic acid biosynthetic process
AL463_RS19095	COG1028	Short-chain dehydrogenase reductase Sdr
AL463_RS19100	COG1309	transcriptional regulator
AL463_RS19135	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AL463_RS19155	COG0668	transmembrane transport
AL463_RS19160	COG3182	Iron-regulated membrane protein
AL463_RS19180	COG2840	Smr protein MutS2
AL463_RS19185	COG0840	transmembrane signaling receptor activity
AL463_RS19195	COG0513	Belongs to the DEAD box helicase family
AL463_RS19205	COG0582	viral genome integration into host DNA
AL463_RS19215	COG2076	Multidrug Resistance protein
AL463_RS19230	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL463_RS19230	COG1013	pyruvate-flavodoxin oxidoreductase activity
AL463_RS19230	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AL463_RS19230	COG0674	pyruvate-flavodoxin oxidoreductase activity
AL463_RS19240	COG3042	response to heat
AL463_RS19245	COG3187	Heat shock protein
AL463_RS19250	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL463_RS19255	COG2911	Protein conserved in bacteria
AL463_RS19265	COG3784	Protein of unknown function (DUF1318)
AL463_RS19280	COG1643	Atp-dependent helicase
AL463_RS19285	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AL463_RS19290	COG3038	cytochrome b561
AL463_RS19295	COG0500	methyltransferase
AL463_RS19305	COG0765	amino acid transport
AL463_RS19315	COG0765	amino acid transport
AL463_RS19320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL463_RS19350	COG0840	transmembrane signaling receptor activity
AL463_RS19355	COG0583	DNA-binding transcription factor activity
AL463_RS19360	COG5383	Protein conserved in bacteria
AL463_RS19365	COG2272	Belongs to the type-B carboxylesterase lipase family
AL463_RS19375	COG2353	YceI-like domain
AL463_RS19380	COG1304	FMN binding
AL463_RS19390	COG1349	DNA-binding transcription factor activity
AL463_RS19395	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AL463_RS19400	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL463_RS19405	COG0434	BtpA family
AL463_RS19410	COG3775	system Galactitol-specific IIC component
AL463_RS19415	COG3414	Phosphotransferase system galactitol-specific IIB component
AL463_RS19425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL463_RS19430	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AL463_RS19435	COG1275	C4-dicarboxylate transporter malic acid transport protein
AL463_RS19440	COG0500	methyltransferase
AL463_RS19450	COG3135	benzoate transporter
AL463_RS19455	COG1396	sequence-specific DNA binding
AL463_RS19460	COG0826	peptidase U32
AL463_RS19485	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
AL463_RS19490	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL463_RS19525	COG3238	Protein conserved in bacteria
AL463_RS19535	COG2130	NADP-dependent
AL463_RS19540	COG1802	Transcriptional regulator
AL463_RS19545	COG4772	TonB-dependent receptor
AL463_RS19580	COG2181	nitrate reductase activity
AL463_RS19585	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AL463_RS19590	COG1140	nitrate reductase beta subunit
AL463_RS19595	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AL463_RS19630	COG0243	molybdopterin cofactor binding
AL463_RS19630	COG3383	formate dehydrogenase (NAD+) activity
AL463_RS19635	COG0243	molybdopterin cofactor binding
AL463_RS19635	COG3383	formate dehydrogenase (NAD+) activity
AL463_RS19640	COG0437	4 iron, 4 sulfur cluster binding
AL463_RS19645	COG2864	formate dehydrogenase
AL463_RS19650	COG1064	alcohol dehydrogenase
AL463_RS19670	COG1764	response to oxidative stress
AL463_RS19685	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AL463_RS19700	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AL463_RS19705	COG1757	Na H antiporter
AL463_RS19710	COG1609	Transcriptional regulator
AL463_RS19755	COG0251	oxidation-reduction process
AL463_RS19760	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AL463_RS19785	COG2271	Major facilitator Superfamily
AL463_RS19790	COG1063	alcohol dehydrogenase
AL463_RS19795	COG2186	Transcriptional regulator
AL463_RS19805	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AL463_RS19810	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AL463_RS19835	COG1773	rubredoxin
AL463_RS19860	COG3781	membrane
AL463_RS19875	COG1012	belongs to the aldehyde dehydrogenase family
AL463_RS19880	COG0583	DNA-binding transcription factor activity
AL463_RS19915	COG2814	Major facilitator Superfamily
AL463_RS19925	COG3111	PFAM Bacterial OB fold (BOF) protein
AL463_RS19930	COG1546	Belongs to the CinA family
AL463_RS19935	COG3729	General stress protein
AL463_RS19945	COG4221	oxidoreductase activity
AL463_RS19950	COG1802	Transcriptional regulator
AL463_RS19960	COG0246	Mannitol dehydrogenase
AL463_RS19970	COG1063	alcohol dehydrogenase
AL463_RS19990	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL463_RS20005	COG0243	molybdopterin cofactor binding
AL463_RS20010	COG0243	molybdopterin cofactor binding
AL463_RS20015	COG0437	4 iron, 4 sulfur cluster binding
AL463_RS20020	COG3302	dmso reductase anchor subunit
AL463_RS20060	COG1940	carbohydrate kinase activity
AL463_RS20065	COG0583	DNA-binding transcription factor activity
AL463_RS20070	COG2814	Major facilitator Superfamily
AL463_RS20080	COG3591	Belongs to the peptidase S1B family
AL463_RS20095	COG0628	permease
AL463_RS20100	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AL463_RS20105	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AL463_RS20115	COG0531	amino acid
AL463_RS20120	COG3136	membrane protein required for alginate biosynthesis
AL463_RS20125	COG0745	RESPONSE REGULATOR receiver
AL463_RS20135	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL463_RS20140	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AL463_RS20145	COG2205	protein histidine kinase activity
AL463_RS20170	COG5339	Protein conserved in bacteria
AL463_RS20175	COG1263	PTS System
AL463_RS20175	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL463_RS20185	COG0673	inositol 2-dehydrogenase activity
AL463_RS20235	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AL463_RS20245	COG0625	glutathione transferase activity
AL463_RS20265	COG3895	Periplasmic Protein
AL463_RS20290	COG1566	PFAM secretion protein HlyD family protein
AL463_RS20305	COG4989	oxidoreductase activity
AL463_RS20310	COG3313	Fe-S protein
AL463_RS20315	COG1309	transcriptional regulator
AL463_RS20320	COG1902	pentaerythritol trinitrate reductase activity
AL463_RS20335	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AL463_RS20340	COG0791	NLP P60 protein
AL463_RS20355	COG0583	DNA-binding transcription factor activity
AL463_RS20360	COG2814	Major facilitator Superfamily
AL463_RS20365	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AL463_RS20370	COG0307	riboflavin synthase, alpha
AL463_RS20550	COG0789	Transcriptional regulator
AL463_RS20555	COG3272	Protein of unknown function (DUF1722)
AL463_RS20590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL463_RS20600	COG2267	carboxylic ester hydrolase activity
AL463_RS20605	COG0531	amino acid
AL463_RS20625	COG1376	ErfK ybiS ycfS ynhG family protein
AL463_RS20640	COG0719	Fe-S assembly protein
AL463_RS20645	COG0396	ATPase activity
AL463_RS20650	COG0719	Fe-S assembly protein
AL463_RS20655	COG0316	Belongs to the HesB IscA family
AL463_RS20660	COG1823	symporter activity
AL463_RS20670	COG2050	protein possibly involved in aromatic compounds catabolism
AL463_RS20675	COG0247	lactate metabolic process
AL463_RS20675	COG0277	FAD linked oxidase domain protein
AL463_RS20680	COG0628	permease
AL463_RS20695	COG0738	Major facilitator superfamily
AL463_RS20715	COG4670	ketone body catabolic process
AL463_RS20720	COG1960	acyl-CoA dehydrogenase activity
AL463_RS20725	COG1917	Cupin 2, conserved barrel domain protein
AL463_RS20725	COG2207	Transcriptional regulator
AL463_RS20730	COG2086	electron transfer activity
AL463_RS20735	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AL463_RS20740	COG0644	oxidoreductase
AL463_RS20745	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AL463_RS20750	COG0318	PFAM AMP-dependent synthetase and ligase
AL463_RS20755	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AL463_RS20755	COG0574	Belongs to the PEP-utilizing enzyme family
AL463_RS20770	COG4256	Hemin uptake protein
AL463_RS20785	COG0791	NLP P60 protein
AL463_RS20795	COG0386	Belongs to the glutathione peroxidase family
AL463_RS20865	COG3137	Salt-induced outer membrane protein
AL463_RS20880	COG3001	Fructosamine kinase
AL463_RS20890	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL463_RS20895	COG1988	membrane-bound metal-dependent
AL463_RS20900	COG1823	symporter activity
AL463_RS20910	COG0753	catalase activity
AL463_RS20920	COG1486	melibiose metabolic process
AL463_RS20925	COG1917	Cupin 2, conserved barrel domain protein
AL463_RS20925	COG2169	Transcriptional regulator
AL463_RS20930	COG1447	Phosphotransferase system cellobiose-specific component IIA
AL463_RS20935	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AL463_RS20940	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AL463_RS20945	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL463_RS20960	COG3678	ATP-independent chaperone mediated protein folding
AL463_RS20995	COG0494	nUDIX hydrolase
AL463_RS21020	COG0778	Nitroreductase
AL463_RS21025	COG0616	signal peptide processing
AL463_RS21030	COG0252	asparaginase activity
AL463_RS21035	COG1335	isochorismatase
AL463_RS21040	COG3139	Protein of unknown function (DUF1315)
AL463_RS21060	COG0656	L-ascorbic acid biosynthetic process
AL463_RS21065	COG0641	radical SAM
AL463_RS21070	COG3713	MltA-interacting MipA family protein
AL463_RS21075	COG2766	serine protein kinase
AL463_RS21085	COG2199	diguanylate cyclase activity
AL463_RS21090	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AL463_RS21105	COG2207	Transcriptional regulator
AL463_RS21110	COG2807	transmembrane transport
AL463_RS21115	COG3189	MarR family transcriptional regulator
AL463_RS21125	COG3042	response to heat
AL463_RS21130	COG2261	transglycosylase associated protein
AL463_RS21150	COG3615	Tellurite resistance protein tehB
AL463_RS21160	COG1605	Chorismate mutase
AL463_RS21175	COG0789	Transcriptional regulator
AL463_RS21190	COG3443	Belongs to the bacterial solute-binding protein 9 family
AL463_RS21205	COG0668	transmembrane transport
AL463_RS21210	COG1124	(ABC) transporter
AL463_RS21240	COG3038	cytochrome b561
AL463_RS21255	COG0071	Belongs to the small heat shock protein (HSP20) family
AL463_RS21345	COG0538	isocitrate dehydrogenase activity
AL463_RS21375	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AL463_RS21390	COG2850	peptidyl-arginine hydroxylation
AL463_RS21420	COG1177	transmembrane transport
AL463_RS21440	COG4591	ABC-type transport system involved in lipoprotein release permease component
AL463_RS21445	COG1136	(ABC) transporter
AL463_RS21450	COG4591	ABC-type transport system involved in lipoprotein release permease component
AL463_RS21455	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AL463_RS21460	COG1376	ErfK ybiS ycfS ynhG family protein
AL463_RS21460	COG1388	LysM domain
AL463_RS21470	COG1309	transcriptional regulator
AL463_RS21475	COG3134	Outer membrane lipoprotein
AL463_RS21480	COG1252	NADH dehydrogenase
AL463_RS21505	COG5633	Lipoprotein
AL463_RS21510	COG0537	adenosine 5'-monophosphoramidase activity
AL463_RS21515	COG4773	Receptor
AL463_RS21525	COG0084	hydrolase, TatD family'
AL463_RS21530	COG0470	DNA polymerase III
AL463_RS21540	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AL463_RS21545	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AL463_RS21550	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL463_RS21615	COG1530	ribonuclease E activity
AL463_RS21705	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL463_RS21715	COG2999	glutathione oxidoreductase activity
AL463_RS21750	COG3038	cytochrome b561
AL463_RS21765	COG1560	Kdo2-lipid A biosynthetic process
AL463_RS21780	COG5645	(Lipo)protein
AL463_RS21800	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL463_RS21855	COG3381	protein complex oligomerization
AL463_RS21895	COG0673	inositol 2-dehydrogenase activity
AL463_RS21900	COG2814	Major facilitator Superfamily
AL463_RS21920	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL463_RS21925	COG1737	Transcriptional regulator
AL463_RS21930	COG1702	phosphate starvation-inducible protein PhoH
AL463_RS21955	COG1309	transcriptional regulator
AL463_RS21960	COG3729	General stress protein
AL463_RS21980	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL463_RS21985	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL463_RS21985	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AL463_RS21990	COG4232	protein-disulfide reductase activity
AL463_RS22035	COG3971	2-oxopent-4-enoate hydratase activity
AL463_RS22045	COG3384	dioxygenase
AL463_RS22050	COG1012	belongs to the aldehyde dehydrogenase family
AL463_RS22060	COG1846	Transcriptional regulator
AL463_RS22065	COG2368	4-hydroxyphenylacetate
AL463_RS22080	COG0745	RESPONSE REGULATOR receiver
AL463_RS22085	COG2205	protein histidine kinase activity
AL463_RS22135	COG0670	Belongs to the BI1 family
AL463_RS22155	COG1881	PFAM PEBP family protein
AL463_RS22170	COG1832	CoA-binding protein
AL463_RS22185	COG0210	DNA helicase
AL463_RS22190	COG3304	Inner membrane component domain
AL463_RS22195	COG1289	transmembrane transporter activity
AL463_RS22200	COG3070	regulator of competence-specific genes
AL463_RS22220	COG1067	ATP-dependent peptidase activity
AL463_RS22230	COG3130	regulation of translation
AL463_RS22235	COG3009	Protein conserved in bacteria
AL463_RS22240	COG3008	intermembrane lipid transfer
AL463_RS22240	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AL463_RS22245	COG2995	paraquat-inducible protein a
AL463_RS22250	COG0488	(ABC) transporter
AL463_RS22260	COG0633	Ferredoxin
AL463_RS22260	COG3217	Mosc domain protein beta barrel domain protein
AL463_RS22275	COG0308	aminopeptidase N
AL463_RS22295	COG2135	peptidase activity
AL463_RS22300	COG4372	Transposase
AL463_RS22315	COG5301	cellulose 1,4-beta-cellobiosidase activity
AL463_RS22465	COG0484	heat shock protein binding
AL463_RS22510	COG1484	DNA-dependent DNA replication
AL463_RS22545	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AL463_RS22565	COG0582	viral genome integration into host DNA
AL463_RS22575	COG1115	amino acid carrier protein
AL463_RS22590	COG1522	sequence-specific DNA binding
AL463_RS22610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AL463_RS22615	COG3108	Peptidase M15
AL463_RS22620	COG2989	Protein conserved in bacteria
AL463_RS22630	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
AL463_RS22640	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL463_RS22645	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AL463_RS22650	COG3173	Aminoglycoside phosphotransferase
AL463_RS22665	COG3214	Protein conserved in bacteria
AL463_RS22680	COG0658	competence protein
AL463_RS22680	COG2333	competence protein COMEC
AL463_RS22690	COG0539	negative regulation of cytoplasmic translation
AL463_RS22700	COG0501	Belongs to the peptidase M48B family
AL463_RS22715	COG2323	membrane
AL463_RS22720	COG1944	ATP diphosphatase activity
AL463_RS22725	COG2116	formate transmembrane transporter activity
AL463_RS22730	COG1882	Formate acetyltransferase
AL463_RS22745	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AL463_RS22750	COG0531	amino acid
AL463_RS22765	COG3302	dmso reductase anchor subunit
AL463_RS22770	COG0437	4 iron, 4 sulfur cluster binding
AL463_RS22775	COG0243	molybdopterin cofactor binding
AL463_RS22785	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AL463_RS22805	COG0492	ferredoxin-NADP+ reductase activity
AL463_RS22810	COG4988	ABC transporter
AL463_RS22815	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AL463_RS22835	COG0583	DNA-binding transcription factor activity
AL463_RS22845	COG1335	isochorismatase
AL463_RS22870	COG0542	response to heat
AL463_RS22880	COG1278	Cold shock
AL463_RS22890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL463_RS22895	COG2990	Protein conserved in bacteria
AL463_RS22900	COG3593	DNA synthesis involved in DNA repair
AL463_RS22905	COG2431	L-lysine efflux transmembrane transporter activity
AL463_RS22915	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL463_RS22920	COG0028	Belongs to the TPP enzyme family
AL463_RS22925	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AL463_RS22930	COG0702	epimerase
AL463_RS22935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL463_RS22940	COG3023	N-Acetylmuramoyl-L-alanine amidase
AL463_RS22965	COG5301	cellulose 1,4-beta-cellobiosidase activity
AL463_RS22995	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AL463_RS23045	COG0740	serine-type endopeptidase activity
AL463_RS23085	COG3179	chitinase
AL463_RS23105	COG0484	heat shock protein binding
AL463_RS23140	COG1396	sequence-specific DNA binding
AL463_RS23210	COG0582	viral genome integration into host DNA
AL463_RS23220	COG1126	abc transporter atp-binding protein
AL463_RS23225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL463_RS23230	COG4215	(ABC) transporter
AL463_RS23235	COG4160	amino acid transport
AL463_RS23240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL463_RS23270	COG1177	transmembrane transport
AL463_RS23275	COG1176	ABC-type spermidine putrescine transport system, permease component I
AL463_RS23280	COG3842	ATPase activity
AL463_RS23285	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AL463_RS23325	COG3226	Transcriptional regulator
AL463_RS23330	COG0738	Major facilitator superfamily
AL463_RS23335	COG0561	phosphatase activity
AL463_RS23340	COG2814	Major facilitator Superfamily
AL463_RS23345	COG0671	phosphoesterase, PA-phosphatase related
AL463_RS23350	COG1349	DNA-binding transcription factor activity
AL463_RS23355	COG1686	Belongs to the peptidase S11 family
AL463_RS23360	COG0625	glutathione transferase activity
AL463_RS23365	COG2133	pyrroloquinoline quinone binding
AL463_RS23370	COG2610	gluconate transmembrane transporter activity
AL463_RS23375	COG0583	DNA-binding transcription factor activity
AL463_RS23385	COG1960	acyl-CoA dehydrogenase activity
AL463_RS23405	COG2301	Belongs to the HpcH HpaI aldolase family
AL463_RS23455	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AL463_RS23460	COG1882	Formate acetyltransferase
AL463_RS23465	COG0561	phosphatase activity
AL463_RS23475	COG0561	phosphatase activity
AL463_RS23485	COG0488	(ABC) transporter
AL463_RS23490	COG1376	ErfK ybiS ycfS ynhG family protein
AL463_RS23495	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AL463_RS23505	COG2194	sulfuric ester hydrolase activity
AL463_RS23510	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AL463_RS23525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL463_RS23530	COG0765	amino acid transport
AL463_RS23535	COG1126	abc transporter atp-binding protein
AL463_RS23540	COG0668	transmembrane transport
AL463_RS23550	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AL463_RS23565	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AL463_RS23575	COG0513	Belongs to the DEAD box helicase family
AL463_RS23580	COG1309	transcriptional regulator
AL463_RS23590	COG1131	(ABC) transporter
AL463_RS23595	COG0842	Transport permease protein
AL463_RS23600	COG0842	Transport permease protein
AL463_RS23610	COG3568	Endonuclease Exonuclease Phosphatase
AL463_RS23620	COG0392	lysyltransferase activity
AL463_RS23640	COG0670	Belongs to the BI1 family
AL463_RS23650	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AL463_RS23660	COG0521	Mo-molybdopterin cofactor biosynthetic process
AL463_RS23715	COG1881	PFAM PEBP family protein
AL463_RS23745	COG4677	pectinesterase activity
AL463_RS23755	COG0561	phosphatase activity
AL463_RS23765	COG4149	molybdate abc transporter
AL463_RS23770	COG0725	ABC transporter, periplasmic molybdate-binding protein
AL463_RS23780	COG3585	molybdate ion transport
AL463_RS23780	COG2005	Transcriptional regulator
AL463_RS23785	COG1119	ATPase activity
AL463_RS23810	COG2017	converts alpha-aldose to the beta-anomer
AL463_RS23820	COG1120	ATPase activity
AL463_RS23825	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL463_RS23850	COG0471	metal ion transport
AL463_RS23850	COG0490	domain, Protein
AL463_RS23855	COG0583	DNA-binding transcription factor activity
AL463_RS23860	COG0583	DNA-binding transcription factor activity
AL463_RS23865	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AL463_RS23870	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AL463_RS23870	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AL463_RS23875	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL463_RS23950	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AL463_RS23955	COG2885	chlorophyll binding
AL463_RS23965	COG3064	Membrane
AL463_RS23970	COG0848	biopolymer transport protein
AL463_RS23975	COG0811	peptide transport
AL463_RS23980	COG0824	Thioesterase
AL463_RS23985	COG3790	cyd operon protein YbgE
AL463_RS23995	COG4890	Cyd operon protein YbgT
AL463_RS24000	COG1294	oxidase, subunit
AL463_RS24005	COG1271	oxidase subunit
AL463_RS24015	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AL463_RS24025	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL463_RS24030	COG0567	Dehydrogenase, E1 component