locus-tag	class	description
S338_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
S338_RS00030	COG4948	Mandelate Racemase Muconate Lactonizing
S338_RS00035	COG2271	Major facilitator Superfamily
S338_RS00040	COG0561	phosphatase activity
S338_RS00045	COG2186	Transcriptional regulator
S338_RS00050	COG3734	2-keto-3-deoxy-galactonokinase
S338_RS00055	COG0800	Aldolase
S338_RS00065	COG2271	Major facilitator Superfamily
S338_RS00070	COG0784	Response regulator, receiver
S338_RS00070	COG2205	protein histidine kinase activity
S338_RS00070	COG2198	Histidine kinase
S338_RS00075	COG1879	ABC-type sugar transport system periplasmic component
S338_RS00080	COG0745	RESPONSE REGULATOR receiver
S338_RS00085	COG3005	denitrification pathway
S338_RS00100	COG1858	cytochrome C peroxidase
S338_RS00110	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
S338_RS00115	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
S338_RS00120	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
S338_RS00130	COG1138	Cytochrome C-type biogenesis protein
S338_RS00135	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S338_RS00140	COG4235	cytochrome complex assembly
S338_RS00140	COG3088	subunit of a heme lyase
S338_RS00145	COG0823	Involved in the tonB-independent uptake of proteins
S338_RS00150	COG5645	(Lipo)protein
S338_RS00170	COG2149	membrane
S338_RS00180	COG0641	radical SAM
S338_RS00190	COG2610	gluconate transmembrane transporter activity
S338_RS00195	COG0583	DNA-binding transcription factor activity
S338_RS00205	COG2814	Major facilitator Superfamily
S338_RS00230	COG0028	Belongs to the TPP enzyme family
S338_RS00235	COG0440	acetolactate synthase activity
S338_RS00240	COG1349	DNA-binding transcription factor activity
S338_RS00250	COG0738	Major facilitator superfamily
S338_RS00285	COG2188	Transcriptional regulator
S338_RS00290	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
S338_RS00290	COG3711	transcriptional antiterminator
S338_RS00295	COG3414	Phosphotransferase system galactitol-specific IIB component
S338_RS00310	COG3423	Transcriptional regulator
S338_RS00315	COG2801	Transposase and inactivated derivatives
S338_RS00320	COG2842	Transposition protein
S338_RS00350	COG4396	Host-nuclease inhibitor protein Gam
S338_RS00390	COG5566	PFAM Mor transcription activator
S338_RS00420	COG0640	Transcriptional regulator
S338_RS00430	COG4373	Mu-like prophage FluMu protein gp28
S338_RS00435	COG4383	Mu-like prophage protein gp29
S338_RS00440	COG2369	cell adhesion
S338_RS00445	COG5005	Phage virion morphogenesis
S338_RS00450	COG4388	Caudovirus prohead serine protease
S338_RS00455	COG4397	Mu-like prophage major head subunit gpT
S338_RS00480	COG4386	tail sheath protein
S338_RS00490	COG4518	Phage tail assembly chaperone proteins, E, or 41 or 14
S338_RS00500	COG4228	DNA circulation
S338_RS00510	COG4384	Bacteriophage Mu Gp45 protein
S338_RS00515	COG4381	Mu-like prophage protein gp46
S338_RS00520	COG3299	homolog of phage Mu protein gp47
S338_RS00530	COG5301	cellulose 1,4-beta-cellobiosidase activity
S338_RS00550	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
S338_RS00600	COG2723	6-phospho-beta-galactosidase activity
S338_RS00620	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S338_RS00620	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
S338_RS00625	COG3715	PTS system
S338_RS00630	COG3716	PTS system mannose fructose sorbose family IID component
S338_RS00645	COG5464	transposase or invertase
S338_RS00675	COG1335	isochorismatase
S338_RS00685	COG3710	Transcriptional regulator
S338_RS00700	COG2771	luxR family
S338_RS00715	COG2211	Major facilitator Superfamily
S338_RS00720	COG1501	Belongs to the glycosyl hydrolase 31 family
S338_RS00725	COG2982	Protein involved in outer membrane biogenesis
S338_RS00730	COG2233	PERMEase
S338_RS00735	COG0786	glutamate:sodium symporter activity
S338_RS00740	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
S338_RS00745	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
S338_RS00750	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
S338_RS00770	COG2860	membrane
S338_RS00780	COG0583	DNA-binding transcription factor activity
S338_RS00785	COG1561	YicC-like family, N-terminal region
S338_RS00810	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
S338_RS00840	COG1519	Transferase
S338_RS00845	COG0859	PFAM glycosyl transferase family 9
S338_RS00850	COG0438	transferase activity, transferring glycosyl groups
S338_RS00925	COG1216	Glycosyl transferase, family 2
S338_RS00930	COG2861	carbohydrate metabolic process
S338_RS00935	COG4942	peptidase
S338_RS00945	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
S338_RS00950	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
S338_RS00970	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
S338_RS00980	COG2186	Transcriptional regulator
S338_RS01010	COG3722	fumarate hydratase activity
S338_RS01020	COG2213	PTS system mannitol-specific
S338_RS01020	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
S338_RS01025	COG0625	glutathione transferase activity
S338_RS01035	COG3276	selenocysteine insertion sequence binding
S338_RS01040	COG1940	carbohydrate kinase activity
S338_RS01045	COG1012	belongs to the aldehyde dehydrogenase family
S338_RS01060	COG0235	Class ii aldolase
S338_RS01065	COG3623	hexulose-6-phosphate isomerase
S338_RS01070	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
S338_RS01075	COG1070	Carbohydrate kinase
S338_RS01080	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
S338_RS01085	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
S338_RS01090	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
S338_RS01100	COG2731	YhcH YjgK YiaL family protein
S338_RS01110	COG1414	Transcriptional regulator
S338_RS01115	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
S338_RS01120	COG3977	Valine--pyruvate aminotransferase
S338_RS01125	COG0366	Alpha amylase catalytic
S338_RS01130	COG2992	FlgJ-related protein
S338_RS01135	COG1609	Transcriptional regulator
S338_RS01135	COG2207	Transcriptional regulator
S338_RS01145	COG1070	Carbohydrate kinase
S338_RS01150	COG4682	membrane
S338_RS01155	COG3274	enterobacterial common antigen metabolic process
S338_RS01185	COG1278	Cold shock
S338_RS01190	COG2944	sequence-specific DNA binding
S338_RS01205	COG2885	chlorophyll binding
S338_RS01210	COG0243	molybdopterin cofactor binding
S338_RS01215	COG0456	acetyltransferase
S338_RS01220	COG2818	Glycosylase
S338_RS01225	COG5571	outer membrane autotransporter
S338_RS01255	COG1609	Transcriptional regulator
S338_RS01270	COG0747	negative chemotaxis
S338_RS01275	COG0601	transmembrane transport
S338_RS01280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
S338_RS01285	COG0444	Belongs to the ABC transporter superfamily
S338_RS01290	COG4608	Belongs to the ABC transporter superfamily
S338_RS01295	COG0814	amino acid
S338_RS01335	COG1215	transferase activity, transferring glycosyl groups
S338_RS01345	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
S338_RS01355	COG2200	EAL domain
S338_RS01355	COG2199	diguanylate cyclase activity
S338_RS01370	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
S338_RS01375	COG2200	EAL domain
S338_RS01380	COG2982	Protein involved in outer membrane biogenesis
S338_RS01385	COG0477	Major facilitator Superfamily
S338_RS01390	COG1295	ribonuclease BN
S338_RS01395	COG0583	DNA-binding transcription factor activity
S338_RS01400	COG2197	response regulator
S338_RS01420	COG2188	Transcriptional regulator
S338_RS01425	COG2222	sugar isomerase
S338_RS01430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
S338_RS01435	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
S338_RS01445	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
S338_RS01450	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
S338_RS01455	COG0671	phosphoesterase, PA-phosphatase related
S338_RS01485	COG0306	phosphate transporter
S338_RS01490	COG2081	HI0933 family
S338_RS01495	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
S338_RS01500	COG1129	ABC transporter
S338_RS01500	COG0842	Transport permease protein
S338_RS01505	COG0842	Transport permease protein
S338_RS01515	COG2091	lysine biosynthetic process via aminoadipic acid
S338_RS01520	COG0628	permease
S338_RS01535	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
S338_RS01555	COG3714	YhhN family
S338_RS01565	COG3776	membrane
S338_RS01570	COG0742	ribosomal rna small subunit methyltransferase
S338_RS01575	COG0552	protein localization to endoplasmic reticulum
S338_RS01580	COG2884	Cell division ATP-binding protein ftsE
S338_RS01585	COG2177	Part of the ABC transporter FtsEX involved in
S338_RS01660	COG0584	glycerophosphoryl diester phosphodiesterase
S338_RS01670	COG0405	Gamma-glutamyltransferase
S338_RS01675	COG1735	metal-dependent hydrolase with the TIM-barrel fold
S338_RS01690	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
S338_RS01695	COG1247	-acetyltransferase
S338_RS01700	COG0673	inositol 2-dehydrogenase activity
S338_RS01705	COG1741	Belongs to the pirin family
S338_RS01710	COG1609	Transcriptional regulator
S338_RS01715	COG3265	gluconokinase activity
S338_RS01720	COG2610	gluconate transmembrane transporter activity
S338_RS01755	COG0058	SHG alpha-glucan phosphorylase activity
S338_RS01760	COG1414	Transcriptional regulator
S338_RS01765	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
S338_RS01770	COG0129	dihydroxy-acid dehydratase activity
S338_RS01780	COG0371	Dehydrogenase
S338_RS01800	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
S338_RS01815	COG1349	DNA-binding transcription factor activity
S338_RS01825	COG0058	SHG alpha-glucan phosphorylase activity
S338_RS01830	COG1640	4-alpha-glucanotransferase
S338_RS01835	COG2610	gluconate transmembrane transporter activity
S338_RS01855	COG5464	transposase or invertase
S338_RS01870	COG1918	ferrous iron import across plasma membrane
S338_RS01875	COG2183	response to ionizing radiation
S338_RS01880	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
S338_RS01900	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
S338_RS01910	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
S338_RS01915	COG1011	Hydrolase
S338_RS01925	COG0494	nUDIX hydrolase
S338_RS01930	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
S338_RS01935	COG4972	Pilus assembly protein
S338_RS01940	COG3166	PFAM Fimbrial assembly family protein
S338_RS01955	COG4796	Type ii and iii secretion system protein
S338_RS01970	COG3266	domain, Protein
S338_RS01975	COG0338	D12 class N6 adenine-specific DNA methyltransferase
S338_RS01980	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
S338_RS02020	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
S338_RS02055	COG1289	transmembrane transporter activity
S338_RS02065	COG1765	OsmC-like protein
S338_RS02070	COG3954	Phosphoribulokinase
S338_RS02080	COG0429	hydrolase of the alpha beta-hydrolase fold
S338_RS02095	COG0488	(ABC) transporter
S338_RS02110	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
S338_RS02115	COG1047	Peptidyl-prolyl cis-trans
S338_RS02125	COG0545	Peptidyl-prolyl cis-trans isomerase
S338_RS02130	COG2964	Protein conserved in bacteria
S338_RS02185	COG0051	transcription antitermination factor activity, RNA binding
S338_RS02210	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
S338_RS02290	COG0201	protein transport
S338_RS02330	COG0789	Transcriptional regulator
S338_RS02335	COG3036	rescue of stalled ribosome
S338_RS02365	COG0758	DNA mediated transformation
S338_RS02375	COG0551	DNA topoisomerase type I activity
S338_RS02395	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
S338_RS02440	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
S338_RS02445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
S338_RS02450	COG1309	transcriptional regulator
S338_RS02465	COG2189	Belongs to the N(4) N(6)-methyltransferase family
S338_RS02490	COG4145	pantothenate transmembrane transporter activity
S338_RS02495	COG3924	membrane
S338_RS02500	COG0439	Biotin carboxylase
S338_RS02505	COG0511	ligase activity, forming carbon-carbon bonds
S338_RS02525	COG0604	alcohol dehydrogenase
S338_RS02530	COG2199	diguanylate cyclase activity
S338_RS02530	COG2200	EAL domain
S338_RS02535	COG1077	Cell shape determining protein MreB Mrl
S338_RS02540	COG1792	Involved in formation and maintenance of cell shape
S338_RS02545	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
S338_RS02560	COG3164	Protein of unknown function
S338_RS02565	COG0312	modulator of DNA gyrase
S338_RS02570	COG0583	DNA-binding transcription factor activity
S338_RS02590	COG2732	(Barnase) inhibitor
S338_RS02615	COG2188	Transcriptional regulator
S338_RS02625	COG0471	metal ion transport
S338_RS02630	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
S338_RS02635	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
S338_RS02645	COG0511	ligase activity, forming carbon-carbon bonds
S338_RS02645	COG5016	pyruvate
S338_RS02650	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
S338_RS02665	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
S338_RS02670	COG3105	Protein conserved in bacteria
S338_RS02675	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
S338_RS02690	COG0625	glutathione transferase activity
S338_RS02695	COG2969	positive regulation of protein catabolic process
S338_RS02725	COG2731	YhcH YjgK YiaL family protein
S338_RS02730	COG0402	S-adenosylhomocysteine deaminase activity
S338_RS02735	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
S338_RS02740	COG4804	nuclease activity
S338_RS02745	COG0493	'glutamate synthase
S338_RS02750	COG0067	glutamate synthase
S338_RS02750	COG0070	glutamate synthase
S338_RS02750	COG0069	glutamate synthase activity
S338_RS02755	COG1242	4 iron, 4 sulfur cluster binding
S338_RS02760	COG2198	Histidine kinase
S338_RS02760	COG5002	protein histidine kinase activity
S338_RS02760	COG0784	Response regulator, receiver
S338_RS02765	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
S338_RS02775	COG0515	serine threonine protein kinase
S338_RS02780	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
S338_RS02800	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
S338_RS02805	COG1137	ATPase activity
S338_RS02810	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
S338_RS02815	COG3117	lipopolysaccharide transmembrane transporter activity
S338_RS02820	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
S338_RS02830	COG0530	calcium, potassium:sodium antiporter activity
S338_RS02835	COG1127	ABC transporter
S338_RS02840	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
S338_RS02845	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
S338_RS02850	COG2854	intermembrane phospholipid transfer
S338_RS02855	COG3113	response to antibiotic
S338_RS02860	COG5007	Belongs to the BolA IbaG family
S338_RS02870	COG3423	Transcriptional regulator
S338_RS02875	COG0142	geranyltranstransferase activity
S338_RS02890	COG0697	spore germination
S338_RS02900	COG2027	D-alanyl-D-alanine carboxypeptidase
S338_RS02910	COG1534	Rna-binding protein
S338_RS02925	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
S338_RS02935	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
S338_RS02950	COG0137	argininosuccinate synthase activity
S338_RS03005	COG0513	Belongs to the DEAD box helicase family
S338_RS03010	COG0814	amino acid
S338_RS03015	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
S338_RS03020	COG0826	peptidase U32
S338_RS03025	COG0826	peptidase U32
S338_RS03030	COG3154	lipid carrier protein
S338_RS03035	COG3153	acetyltransferase
S338_RS03050	COG0693	protein deglycase activity
S338_RS03055	COG0702	epimerase
S338_RS03060	COG2823	Periplasmic or secreted lipoprotein
S338_RS03080	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
S338_RS03090	COG1063	alcohol dehydrogenase
S338_RS03095	COG3775	system Galactitol-specific IIC component
S338_RS03100	COG3414	Phosphotransferase system galactitol-specific IIB component
S338_RS03105	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
S338_RS03135	COG1349	DNA-binding transcription factor activity
S338_RS03140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
S338_RS03145	COG2721	sulfolactate sulfo-lyase activity
S338_RS03155	COG2084	Dehydrogenase
S338_RS03160	COG1929	Belongs to the glycerate kinase type-1 family
S338_RS03170	COG0583	DNA-binding transcription factor activity
S338_RS03190	COG1882	Formate acetyltransferase
S338_RS03195	COG1760	l-serine dehydratase
S338_RS03200	COG0814	amino acid
S338_RS03215	COG1741	Belongs to the pirin family
S338_RS03220	COG0583	DNA-binding transcription factor activity
S338_RS03225	COG3152	Membrane
S338_RS03230	COG0435	Glutathione S-transferase
S338_RS03235	COG2259	Doxx family
S338_RS03245	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
S338_RS03250	COG4575	ribosome binding
S338_RS03255	COG1422	Protein of unknown function (DUF1090)
S338_RS03265	COG0586	Pfam SNARE associated Golgi protein
S338_RS03280	COG0673	inositol 2-dehydrogenase activity
S338_RS03285	COG2949	membrane
S338_RS03290	COG1451	nucleotide metabolic process
S338_RS03300	COG1902	pentaerythritol trinitrate reductase activity
S338_RS03300	COG0446	pyridine nucleotide-disulphide oxidoreductase
S338_RS03310	COG0840	transmembrane signaling receptor activity
S338_RS03315	COG0840	transmembrane signaling receptor activity
S338_RS03320	COG1695	Transcriptional regulator
S338_RS03325	COG2375	cellular response to nickel ion
S338_RS03350	COG0828	Belongs to the bacterial ribosomal protein bS21 family
S338_RS03370	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
S338_RS03385	COG4991	sh3 domain protein
S338_RS03390	COG3025	triphosphatase activity
S338_RS03410	COG2268	Band 7 protein
S338_RS03415	COG1585	Membrane protein implicated in regulation of membrane protease activity
S338_RS03455	COG3384	dioxygenase
S338_RS03460	COG0754	glutathionylspermidine amidase activity
S338_RS03475	COG0494	nUDIX hydrolase
S338_RS03480	COG3151	Protein conserved in bacteria
S338_RS03485	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
S338_RS03490	COG3150	esterase
S338_RS03500	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
S338_RS03505	COG2249	NAD(P)H dehydrogenase (quinone) activity
S338_RS03520	COG3111	PFAM Bacterial OB fold (BOF) protein
S338_RS03525	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
S338_RS03565	COG1032	radical SAM domain protein
S338_RS03590	COG1979	alcohol dehydrogenase
S338_RS03595	COG2207	Transcriptional regulator
S338_RS03615	COG0848	biopolymer transport protein
S338_RS03620	COG1028	Short-chain dehydrogenase reductase Sdr
S338_RS03645	COG0840	transmembrane signaling receptor activity
S338_RS03655	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
S338_RS03660	COG0437	4 iron, 4 sulfur cluster binding
S338_RS03665	COG5557	Pfam Polysulphide reductase, NrfD
S338_RS03670	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
S338_RS03675	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
S338_RS03680	COG1773	rubredoxin
S338_RS03690	COG0298	carbon dioxide binding
S338_RS03695	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
S338_RS03705	COG0625	glutathione transferase activity
S338_RS03710	COG0754	glutathionylspermidine amidase activity
S338_RS03725	COG0246	Mannitol dehydrogenase
S338_RS03735	COG2271	Major facilitator Superfamily
S338_RS03750	COG3250	beta-galactosidase activity
S338_RS03755	COG1309	transcriptional regulator
S338_RS03780	COG1012	belongs to the aldehyde dehydrogenase family
S338_RS03785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
S338_RS03795	COG0531	amino acid
S338_RS03825	COG2301	Belongs to the HpcH HpaI aldolase family
S338_RS03830	COG2030	dehydratase
S338_RS03835	COG0427	acetyl-CoA hydrolase
S338_RS03850	COG1811	Na channel or pump
S338_RS03855	COG1982	Orn Lys Arg decarboxylase major
S338_RS03860	COG2211	Major facilitator Superfamily
S338_RS03885	COG3171	Protein conserved in bacteria
S338_RS03895	COG0252	asparaginase activity
S338_RS03905	COG0635	Involved in the biosynthesis of porphyrin-containing compound
S338_RS03920	COG0762	integral membrane protein
S338_RS03925	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
S338_RS03930	COG2805	Type II/IV secretion system protein
S338_RS03955	COG1385	rRNA (uridine-N3-)-methyltransferase activity
S338_RS03960	COG2356	endonuclease I
S338_RS03970	COG2814	Major facilitator Superfamily
S338_RS03990	COG1166	arginine decarboxylase activity
S338_RS04000	COG0501	Belongs to the peptidase M48B family
S338_RS04005	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
S338_RS04015	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
S338_RS04020	COG2213	PTS system mannitol-specific
S338_RS04025	COG1063	alcohol dehydrogenase
S338_RS04030	COG1494	fructose-1,6-bisphosphatase
S338_RS04040	COG1072	(Pantothenic acid kinase))
S338_RS04045	COG1122	ATPase activity
S338_RS04050	COG1122	ATPase activity
S338_RS04080	COG0191	fructose-bisphosphate aldolase activity
S338_RS04085	COG0668	transmembrane transport
S338_RS04095	COG2968	Membrane
S338_RS04115	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
S338_RS04120	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
S338_RS04140	COG0006	proline dipeptidase activity
S338_RS04145	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
S338_RS04150	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
S338_RS04180	COG2723	6-phospho-beta-galactosidase activity
S338_RS04190	COG1272	protein, Hemolysin III
S338_RS04250	COG4942	peptidase
S338_RS04290	COG3188	usher protein
S338_RS04325	COG0814	amino acid
S338_RS04340	COG0183	Belongs to the thiolase family
S338_RS04350	COG1028	Short-chain dehydrogenase reductase Sdr
S338_RS04355	COG2814	Major facilitator Superfamily
S338_RS04360	COG1794	racemase activity, acting on amino acids and derivatives
S338_RS04365	COG0583	DNA-binding transcription factor activity
S338_RS04375	COG1609	Transcriptional regulator
S338_RS04390	COG0477	Major facilitator Superfamily
S338_RS04395	COG0667	Aldo Keto reductase
S338_RS04405	COG0861	Integral membrane protein TerC family
S338_RS04440	COG2165	general secretion pathway protein
S338_RS04445	COG4795	General secretion pathway protein
S338_RS04455	COG4967	type IV pilus modification protein PilV
S338_RS04460	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
S338_RS04465	COG1025	Belongs to the peptidase M16 family
S338_RS04470	COG1074	ATP-dependent DNA helicase activity
S338_RS04475	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
S338_RS04485	COG0860	N-Acetylmuramoyl-L-alanine amidase
S338_RS04500	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
S338_RS04505	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
S338_RS04510	COG2962	Rard protein
S338_RS04515	COG2166	iron-sulfur cluster assembly
S338_RS04520	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
S338_RS04530	COG0583	DNA-binding transcription factor activity
S338_RS04535	COG2363	Small membrane protein
S338_RS04545	COG1349	DNA-binding transcription factor activity
S338_RS04565	COG0738	Major facilitator superfamily
S338_RS04570	COG0235	Class ii aldolase
S338_RS04575	COG1454	alcohol dehydrogenase
S338_RS04585	COG1760	l-serine dehydratase
S338_RS04590	COG0814	amino acid
S338_RS04595	COG1611	Belongs to the LOG family
S338_RS04615	COG3098	single-species biofilm formation
S338_RS04625	COG0716	FMN binding
S338_RS04630	COG2271	Major facilitator Superfamily
S338_RS04635	COG4948	Mandelate Racemase Muconate Lactonizing
S338_RS04640	COG4948	Mandelate Racemase Muconate Lactonizing
S338_RS04645	COG1929	Belongs to the glycerate kinase type-1 family
S338_RS04650	COG2205	protein histidine kinase activity
S338_RS04650	COG3437	response regulator, receiver
S338_RS04650	COG4999	Histidine kinase
S338_RS04650	COG3850	Histidine kinase
S338_RS04660	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
S338_RS04665	COG3609	addiction module antidote protein, CC2985 family
S338_RS04680	COG3956	TIGRFAM MazG family protein
S338_RS04695	COG0602	queuosine metabolic process
S338_RS04700	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
S338_RS04700	COG0321	lipoyl(octanoyl) transferase activity
S338_RS04705	COG0720	synthase
S338_RS04730	COG1203	CRISPR-associated helicase, Cas3
S338_RS04745	COG1857	crispr-associated protein
S338_RS04760	COG1518	maintenance of DNA repeat elements
S338_RS04765	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
S338_RS04770	COG2234	aminopeptidase activity
S338_RS04840	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
S338_RS04845	COG0163	prenyltransferase activity
S338_RS04855	COG1349	DNA-binding transcription factor activity
S338_RS04860	COG2084	Dehydrogenase
S338_RS04870	COG0235	Class ii aldolase
S338_RS04875	COG3622	Belongs to the hyi family
S338_RS04880	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
S338_RS04885	COG2610	gluconate transmembrane transporter activity
S338_RS04895	COG0477	Major facilitator Superfamily
S338_RS04975	COG2207	Transcriptional regulator
S338_RS05065	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
S338_RS05150	COG1108	ABC-type Mn2 Zn2 transport systems permease components
S338_RS05155	COG1108	ABC-type Mn2 Zn2 transport systems permease components
S338_RS05160	COG1121	(ABC) transporter
S338_RS05180	COG0309	Hydrogenase expression formation protein (HypE)
S338_RS05185	COG0409	Hydrogenase expression formation protein
S338_RS05190	COG0298	carbon dioxide binding
S338_RS05195	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
S338_RS05210	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
S338_RS05215	COG0651	ATP synthesis coupled electron transport
S338_RS05220	COG0650	Formate hydrogenlyase subunit 4
S338_RS05225	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
S338_RS05225	COG3261	NADH dehydrogenase
S338_RS05230	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
S338_RS05235	COG3260	NADH ubiquinone oxidoreductase 20
S338_RS05245	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
S338_RS05255	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
S338_RS05260	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
S338_RS05280	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
S338_RS05280	COG0517	IMP dehydrogenase activity
S338_RS05285	COG1349	DNA-binding transcription factor activity
S338_RS05290	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
S338_RS05295	COG1028	Short-chain dehydrogenase reductase Sdr
S338_RS05305	COG3732	PTS system glucitol sorbitol-specific
S338_RS05310	COG3730	PTS system glucitol sorbitol-specific
S338_RS05315	COG2951	lytic endotransglycosylase activity
S338_RS05325	COG1546	Belongs to the CinA family
S338_RS05350	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
S338_RS05385	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
S338_RS05390	COG1238	metal cluster binding
S338_RS05410	COG2814	Major facilitator Superfamily
S338_RS05415	COG1566	PFAM secretion protein HlyD family protein
S338_RS05420	COG1846	Transcriptional regulator
S338_RS05425	COG2814	Major facilitator Superfamily
S338_RS05470	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
S338_RS05480	COG4575	ribosome binding
S338_RS05510	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
S338_RS05515	COG0640	Transcriptional regulator
S338_RS05520	COG0401	homolog of Blt101
S338_RS05530	COG1652	LysM domain
S338_RS05535	COG1802	Transcriptional regulator
S338_RS05540	COG1113	amino acid transport
S338_RS05545	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
S338_RS05550	COG1012	belongs to the aldehyde dehydrogenase family
S338_RS05555	COG0579	oxidoreductase
S338_RS05590	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
S338_RS05605	COG2990	Protein conserved in bacteria
S338_RS05625	COG2819	hydrolase of the alpha beta superfamily
S338_RS05695	COG0582	viral genome integration into host DNA
S338_RS05705	COG4974	Belongs to the 'phage' integrase family
S338_RS05780	COG4695	Portal protein
S338_RS05885	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
S338_RS05935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
S338_RS05960	COG2867	negative regulation of translational initiation
S338_RS05975	COG0497	DNA recombination
S338_RS05995	COG4536	flavin adenine dinucleotide binding
S338_RS06000	COG4137	Cytochrome C assembly protein
S338_RS06005	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
S338_RS06030	COG2199	diguanylate cyclase activity
S338_RS06045	COG0287	Prephenate dehydrogenase
S338_RS06045	COG1605	Chorismate mutase
S338_RS06055	COG0077	Prephenate dehydratase
S338_RS06055	COG1605	Chorismate mutase
S338_RS06065	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
S338_RS06075	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
S338_RS06090	COG0542	response to heat
S338_RS06120	COG0477	Major facilitator Superfamily
S338_RS06125	COG5544	Lipoprotein
S338_RS06130	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
S338_RS06140	COG3148	PFAM DTW domain containing protein
S338_RS06145	COG3118	belongs to the thioredoxin family
S338_RS06150	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
S338_RS06170	COG0583	DNA-binding transcription factor activity
S338_RS06175	COG0513	Belongs to the DEAD box helicase family
S338_RS06185	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
S338_RS06215	COG3086	response to oxidative stress
S338_RS06255	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
S338_RS06260	COG0583	DNA-binding transcription factor activity
S338_RS06265	COG2223	nitrite transmembrane transporter activity
S338_RS06270	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
S338_RS06275	COG1737	Transcriptional regulator
S338_RS06285	COG1263	PTS System
S338_RS06285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S338_RS06290	COG0560	Phosphoserine phosphatase
S338_RS06315	COG2205	protein histidine kinase activity
S338_RS06320	COG3170	Tfp pilus assembly protein FimV
S338_RS06325	COG2204	response regulator
S338_RS06330	COG0347	Belongs to the P(II) protein family
S338_RS06335	COG3104	oligopeptide transport
S338_RS06345	COG0531	amino acid
S338_RS06350	COG3710	Transcriptional regulator
S338_RS06355	COG1017	nitric oxide dioxygenase activity
S338_RS06355	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
S338_RS06365	COG2814	Major facilitator Superfamily
S338_RS06370	COG3711	transcriptional antiterminator
S338_RS06380	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
S338_RS06425	COG0822	iron-sulfur transferase activity
S338_RS06445	COG0633	Ferredoxin
S338_RS06450	COG2975	iron-sulfur cluster assembly
S338_RS06465	COG2897	thiosulfate sulfurtransferase activity
S338_RS06470	COG2373	Large extracellular alpha-helical protein
S338_RS06475	COG4953	penicillin-binding protein 1C
S338_RS06480	COG0243	molybdopterin cofactor binding
S338_RS06485	COG0437	4 iron, 4 sulfur cluster binding
S338_RS06525	COG2976	Protein conserved in bacteria
S338_RS06540	COG1645	bacterial-type flagellum-dependent swarming motility
S338_RS06580	COG0517	IMP dehydrogenase activity
S338_RS06580	COG0516	GMP reductase activity
S338_RS06590	COG4316	Uncharacterized protein conserved in bacteria (DUF2251)
S338_RS06620	COG3133	Outer membrane lipoprotein
S338_RS06635	COG2200	EAL domain
S338_RS06650	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
S338_RS06670	COG2233	PERMEase
S338_RS06680	COG1393	Belongs to the ArsC family
S338_RS06690	COG0628	permease
S338_RS06695	COG1929	Belongs to the glycerate kinase type-1 family
S338_RS06700	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
S338_RS06705	COG2716	regulation of RNA biosynthetic process
S338_RS06715	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
S338_RS06725	COG2321	neutral zinc metallopeptidase
S338_RS06745	COG1393	Belongs to the ArsC family
S338_RS06755	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
S338_RS06760	COG3850	Histidine kinase
S338_RS06765	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
S338_RS06765	COG0493	'glutamate synthase
S338_RS06780	COG5342	invasion associated locus B
S338_RS06790	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
S338_RS06915	COG2837	iron assimilation
S338_RS06935	COG4208	sulfate ABC transporter
S338_RS06990	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
S338_RS07015	COG3530	Putative quorum-sensing-regulated virulence factor
S338_RS07020	COG0385	Bile acid
S338_RS07025	COG0583	DNA-binding transcription factor activity
S338_RS07035	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
S338_RS07040	COG2211	Major facilitator Superfamily
S338_RS07050	COG0583	DNA-binding transcription factor activity
S338_RS07080	COG3415	Transposase
S338_RS07085	COG3415	Transposase
S338_RS07100	COG2200	EAL domain
S338_RS07100	COG2199	diguanylate cyclase activity
S338_RS07105	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
S338_RS07120	COG0667	Aldo Keto reductase
S338_RS07125	COG3961	Belongs to the TPP enzyme family
S338_RS07140	COG0436	Aminotransferase
S338_RS07150	COG1560	Kdo2-lipid A biosynthetic process
S338_RS07215	COG2116	formate transmembrane transporter activity
S338_RS07230	COG3691	Protein conserved in bacteria
S338_RS07245	COG2062	phosphohistidine phosphatase, SixA
S338_RS07270	COG0730	response to heat
S338_RS07275	COG3101	peptidyl-lysine hydroxylation
S338_RS07290	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
S338_RS07335	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
S338_RS07345	COG0586	Pfam SNARE associated Golgi protein
S338_RS07355	COG0285	dihydrofolate synthase activity
S338_RS07360	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
S338_RS07365	COG1286	toxin biosynthetic process
S338_RS07370	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
S338_RS07375	COG3829	transcription factor binding
S338_RS07385	COG0531	amino acid
S338_RS07390	COG3457	Alanine racemase
S338_RS07395	COG0833	amino acid
S338_RS07430	COG1090	epimerase
S338_RS07435	COG0625	glutathione transferase activity
S338_RS07440	COG0625	glutathione transferase activity
S338_RS07445	COG0622	Phosphoesterase
S338_RS07455	COG1609	Transcriptional regulator
S338_RS07460	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
S338_RS07470	COG3037	sugar-specific permease SgaT UlaA
S338_RS07475	COG3959	Transketolase, thiamine diphosphate binding domain
S338_RS07480	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
S338_RS07485	COG1288	antiporter activity
S338_RS07510	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
S338_RS07515	COG0471	metal ion transport
S338_RS07515	COG0490	domain, Protein
S338_RS07525	COG0436	Aminotransferase
S338_RS07530	COG0583	DNA-binding transcription factor activity
S338_RS07580	COG0839	Belongs to the complex I subunit 6 family
S338_RS07590	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
S338_RS07595	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
S338_RS07605	COG0835	chemotaxis
S338_RS07605	COG0784	Response regulator, receiver
S338_RS07615	COG2153	protein acetylation
S338_RS07620	COG4575	ribosome binding
S338_RS07625	COG1169	isochorismate synthase
S338_RS07715	COG1414	Transcriptional regulator
S338_RS07725	COG2271	Major facilitator Superfamily
S338_RS07745	COG0247	lactate metabolic process
S338_RS07755	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
S338_RS07760	COG2271	Major facilitator Superfamily
S338_RS07765	COG0584	glycerophosphoryl diester phosphodiesterase
S338_RS07770	COG0583	DNA-binding transcription factor activity
S338_RS07775	COG2814	Major facilitator Superfamily
S338_RS07780	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
S338_RS07810	COG4948	Mandelate Racemase Muconate Lactonizing
S338_RS07830	COG2198	Histidine kinase
S338_RS07830	COG0642	Histidine kinase
S338_RS07855	COG4615	Cyclic peptide transporter
S338_RS07865	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
S338_RS07865	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
S338_RS07870	COG3062	negative regulation of establishment of protein localization
S338_RS07880	COG0437	4 iron, 4 sulfur cluster binding
S338_RS07885	COG0348	domain, Protein
S338_RS07890	COG3043	anaerobic respiration
S338_RS07895	COG3005	denitrification pathway
S338_RS07905	COG1138	Cytochrome C-type biogenesis protein
S338_RS07910	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S338_RS07915	COG4235	cytochrome complex assembly
S338_RS07915	COG3088	subunit of a heme lyase
S338_RS07920	COG2197	response regulator
S338_RS07965	COG1061	Type III restriction enzyme res subunit
S338_RS07975	COG2814	Major facilitator Superfamily
S338_RS07985	COG4172	Belongs to the ABC transporter superfamily
S338_RS07990	COG4239	(ABC) transporter, permease
S338_RS07995	COG4174	ABC transporter (Permease)
S338_RS08000	COG4166	transmembrane transport
S338_RS08005	COG2200	EAL domain
S338_RS08010	COG0791	NLP P60 protein
S338_RS08015	COG0671	phosphoesterase, PA-phosphatase related
S338_RS08020	COG0523	cobalamin synthesis protein
S338_RS08055	COG1105	Belongs to the carbohydrate kinase PfkB family
S338_RS08060	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
S338_RS08060	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
S338_RS08060	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
S338_RS08070	COG2855	membrane
S338_RS08075	COG0583	DNA-binding transcription factor activity
S338_RS08080	COG0833	amino acid
S338_RS08085	COG4771	TonB-dependent receptor
S338_RS08090	COG2271	Major facilitator Superfamily
S338_RS08095	COG0560	Phosphoserine phosphatase
S338_RS08100	COG1760	l-serine dehydratase
S338_RS08120	COG2311	Membrane
S338_RS08160	COG2949	membrane
S338_RS08170	COG1346	cytolysis
S338_RS08185	COG2271	Major facilitator Superfamily
S338_RS08200	COG0625	glutathione transferase activity
S338_RS08205	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
S338_RS08220	COG1538	Outer membrane efflux protein
S338_RS08225	COG1028	Short-chain dehydrogenase reductase Sdr
S338_RS08230	COG0586	Pfam SNARE associated Golgi protein
S338_RS08240	COG1686	Belongs to the peptidase S11 family
S338_RS08245	COG0277	FAD linked oxidase domain protein
S338_RS08255	COG1732	Glycine betaine
S338_RS08260	COG1174	glycine betaine transport
S338_RS08265	COG1125	glycine betaine transport
S338_RS08270	COG1174	glycine betaine transport
S338_RS08285	COG3275	phosphorelay sensor kinase activity
S338_RS08295	COG4807	Protein conserved in bacteria
S338_RS08305	COG4808	Protein conserved in bacteria
S338_RS08330	COG3121	Chaperone
S338_RS08335	COG3188	usher protein
S338_RS08345	COG5455	response to cobalt ion
S338_RS08360	COG2188	Transcriptional regulator
S338_RS08365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
S338_RS08370	COG1397	ADP-ribosylglycohydrolase
S338_RS08375	COG2211	Major facilitator Superfamily
S338_RS08380	COG1830	Aldolase
S338_RS08405	COG0826	peptidase U32
S338_RS08425	COG0745	RESPONSE REGULATOR receiver
S338_RS08430	COG2205	protein histidine kinase activity
S338_RS08460	COG0443	Heat shock 70 kDa protein
S338_RS08465	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
S338_RS08470	COG5002	protein histidine kinase activity
S338_RS08470	COG5001	Diguanylate cyclase
S338_RS08470	COG3447	MASE1 domain protein
S338_RS08485	COG2982	Protein involved in outer membrane biogenesis
S338_RS08490	COG1253	flavin adenine dinucleotide binding
S338_RS08510	COG0463	Glycosyl transferase, family 2
S338_RS08515	COG1045	serine acetyltransferase
S338_RS08520	COG0438	transferase activity, transferring glycosyl groups
S338_RS08530	COG1216	Glycosyl transferase, family 2
S338_RS08535	COG0110	maltose O-acetyltransferase activity
S338_RS08540	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
S338_RS08545	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
S338_RS08550	COG1051	belongs to the nudix hydrolase family
S338_RS08555	COG0297	glycogen (starch) synthase activity
S338_RS08570	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
S338_RS08575	COG2244	polysaccharide biosynthetic process
S338_RS08580	COG2327	Polysaccharide pyruvyl transferase
S338_RS08610	COG0438	transferase activity, transferring glycosyl groups
S338_RS08695	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
S338_RS08700	COG0583	DNA-binding transcription factor activity
S338_RS08710	COG0531	amino acid
S338_RS08715	COG2925	Exonuclease
S338_RS08755	COG1289	transmembrane transporter activity
S338_RS08790	COG4656	Part of a membrane complex involved in electron transport
S338_RS08795	COG1012	belongs to the aldehyde dehydrogenase family
S338_RS08795	COG1454	alcohol dehydrogenase
S338_RS08810	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
S338_RS08825	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
S338_RS08955	COG1122	ATPase activity
S338_RS09000	COG0640	Transcriptional regulator
S338_RS09005	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
S338_RS09020	COG0798	PFAM Bile acid sodium symporter
S338_RS09035	COG0534	Mate efflux family protein
S338_RS09060	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
S338_RS09120	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
S338_RS09130	COG1418	mRNA catabolic process
S338_RS09135	COG0270	DNA (cytosine-5-)-methyltransferase activity
S338_RS09140	COG3727	T/G mismatch-specific endonuclease activity
S338_RS09145	COG0697	spore germination
S338_RS09150	COG2354	Protein conserved in bacteria
S338_RS09155	COG5475	Uncharacterized small protein (DUF2158)
S338_RS09260	COG0425	Belongs to the sulfur carrier protein TusA family
S338_RS09320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
S338_RS09330	COG0765	amino acid transport
S338_RS09335	COG1126	abc transporter atp-binding protein
S338_RS09340	COG2197	response regulator
S338_RS09355	COG2197	response regulator
S338_RS09400	COG3012	SEC-C Motif Domain Protein
S338_RS09400	COG3318	Belongs to the UPF0149 family
S338_RS09405	COG0814	amino acid
S338_RS09415	COG1528	Iron-storage protein
S338_RS09430	COG1528	Iron-storage protein
S338_RS09535	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
S338_RS09550	COG3102	Protein conserved in bacteria
S338_RS09570	COG3788	relative of glutathione S-transferase, MAPEG superfamily
S338_RS09575	COG1801	Protein of unknown function DUF72
S338_RS09580	COG1335	isochorismatase
S338_RS09590	COG0494	nUDIX hydrolase
S338_RS09625	COG1108	ABC-type Mn2 Zn2 transport systems permease components
S338_RS09635	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
S338_RS09640	COG0739	heme binding
S338_RS09645	COG1560	Kdo2-lipid A biosynthetic process
S338_RS09655	COG1737	Transcriptional regulator
S338_RS09660	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
S338_RS09665	COG0129	dihydroxy-acid dehydratase activity
S338_RS09670	COG0800	Aldolase
S338_RS09680	COG3141	response to X-ray
S338_RS09690	COG2979	Protein of unknown function (DUF533)
S338_RS09695	COG1770	oligopeptidase
S338_RS09700	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
S338_RS09705	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
S338_RS09715	COG2372	response to copper ion
S338_RS09720	COG1276	copper resistance
S338_RS09815	COG5562	phage envelope protein
S338_RS09850	COG3008	intermembrane lipid transfer
S338_RS09855	COG2995	paraquat-inducible protein a
S338_RS09860	COG1956	GAF domain-containing protein
S338_RS09880	COG2814	Major facilitator Superfamily
S338_RS09885	COG1414	Transcriptional regulator
S338_RS09915	COG0768	penicillin binding
S338_RS09920	COG2226	methyltransferase
S338_RS09935	COG3716	PTS system mannose fructose sorbose family IID component
S338_RS09940	COG3715	PTS system
S338_RS09945	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
S338_RS09945	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S338_RS09950	COG1253	flavin adenine dinucleotide binding
S338_RS09955	COG2200	EAL domain
S338_RS09960	COG1760	l-serine dehydratase
S338_RS09980	COG0251	oxidation-reduction process
S338_RS09985	COG1199	ATP-dependent helicase activity
S338_RS09995	COG3065	identical protein binding
S338_RS10005	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
S338_RS10015	COG2894	cell division
S338_RS10030	COG0179	Fumarylacetoacetate (FAA) hydrolase
S338_RS10070	COG2719	SpoVR family
S338_RS10090	COG1619	proteins homologs of microcin C7 resistance protein MccF
S338_RS10115	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
S338_RS10125	COG1294	oxidase, subunit
S338_RS10130	COG1271	oxidase subunit
S338_RS10135	COG1773	rubredoxin
S338_RS10140	COG1999	signal sequence binding
S338_RS10145	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
S338_RS10150	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
S338_RS10160	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
S338_RS10170	COG0012	GTP binding
S338_RS10185	COG0659	secondary active sulfate transmembrane transporter activity
S338_RS10245	COG0387	Pfam Sodium calcium exchanger
S338_RS10250	COG4572	Cation transport regulator
S338_RS10255	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
S338_RS10260	COG4932	domain protein
S338_RS10265	COG2197	response regulator
S338_RS10270	COG3850	Histidine kinase
S338_RS10275	COG2223	nitrite transmembrane transporter activity
S338_RS10280	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
S338_RS10285	COG1140	nitrate reductase beta subunit
S338_RS10290	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
S338_RS10295	COG2181	nitrate reductase activity
S338_RS10335	COG0788	formyltetrahydrofolate deformylase activity
S338_RS10345	COG1752	Esterase of the alpha-beta hydrolase superfamily
S338_RS10350	COG0745	RESPONSE REGULATOR receiver
S338_RS10355	COG1210	Utp--glucose-1-phosphate uridylyltransferase
S338_RS10370	COG1454	alcohol dehydrogenase
S338_RS10370	COG1012	belongs to the aldehyde dehydrogenase family
S338_RS10375	COG2095	MarC family integral membrane protein
S338_RS10405	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
S338_RS10425	COG2350	Protein conserved in bacteria
S338_RS10450	COG0727	PFAM Uncharacterised protein family (UPF0153)
S338_RS10460	COG3546	catalase activity
S338_RS10465	COG3685	Protein conserved in bacteria
S338_RS10470	COG3685	Protein conserved in bacteria
S338_RS10475	COG3729	General stress protein
S338_RS10515	COG0009	L-threonylcarbamoyladenylate synthase
S338_RS10530	COG1028	Short-chain dehydrogenase reductase Sdr
S338_RS10535	COG0616	signal peptide processing
S338_RS10580	COG0671	phosphoesterase, PA-phosphatase related
S338_RS10585	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
S338_RS10590	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
S338_RS10610	COG1349	DNA-binding transcription factor activity
S338_RS10620	COG5001	Diguanylate cyclase
S338_RS10630	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
S338_RS10630	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
S338_RS10720	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
S338_RS10735	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
S338_RS10740	COG1842	Phage shock protein A
S338_RS10750	COG1983	PspC domain protein
S338_RS10765	COG3106	COG3106 Predicted ATPase
S338_RS10785	COG4948	Mandelate Racemase Muconate Lactonizing
S338_RS10790	COG2866	Carboxypeptidase
S338_RS10795	COG4166	transmembrane transport
S338_RS10805	COG0583	DNA-binding transcription factor activity
S338_RS10810	COG0656	L-ascorbic acid biosynthetic process
S338_RS10815	COG1028	Short-chain dehydrogenase reductase Sdr
S338_RS10820	COG1309	transcriptional regulator
S338_RS10855	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
S338_RS10875	COG0668	transmembrane transport
S338_RS10880	COG3182	Iron-regulated membrane protein
S338_RS10900	COG2840	Smr protein MutS2
S338_RS10905	COG0840	transmembrane signaling receptor activity
S338_RS10920	COG0513	Belongs to the DEAD box helicase family
S338_RS10945	COG2076	Multidrug Resistance protein
S338_RS10955	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
S338_RS10955	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
S338_RS10955	COG0674	pyruvate-flavodoxin oxidoreductase activity
S338_RS10955	COG1013	pyruvate-flavodoxin oxidoreductase activity
S338_RS10965	COG3042	response to heat
S338_RS10970	COG3187	Heat shock protein
S338_RS10975	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
S338_RS10980	COG2911	Protein conserved in bacteria
S338_RS10990	COG3784	Protein of unknown function (DUF1318)
S338_RS11005	COG1643	Atp-dependent helicase
S338_RS11010	COG1434	Gram-negative-bacterium-type cell wall biogenesis
S338_RS11015	COG3038	cytochrome b561
S338_RS11020	COG0500	methyltransferase
S338_RS11030	COG0765	amino acid transport
S338_RS11040	COG0765	amino acid transport
S338_RS11045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
S338_RS11080	COG0840	transmembrane signaling receptor activity
S338_RS11085	COG0583	DNA-binding transcription factor activity
S338_RS11090	COG5383	Protein conserved in bacteria
S338_RS11095	COG2272	Belongs to the type-B carboxylesterase lipase family
S338_RS11105	COG2353	YceI-like domain
S338_RS11110	COG1304	FMN binding
S338_RS11120	COG1349	DNA-binding transcription factor activity
S338_RS11125	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
S338_RS11130	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
S338_RS11135	COG0434	BtpA family
S338_RS11140	COG3775	system Galactitol-specific IIC component
S338_RS11145	COG3414	Phosphotransferase system galactitol-specific IIB component
S338_RS11155	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
S338_RS11160	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
S338_RS11165	COG1275	C4-dicarboxylate transporter malic acid transport protein
S338_RS11170	COG0500	methyltransferase
S338_RS11180	COG3135	benzoate transporter
S338_RS11185	COG1396	sequence-specific DNA binding
S338_RS11190	COG0826	peptidase U32
S338_RS11215	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
S338_RS11220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
S338_RS11260	COG3238	Protein conserved in bacteria
S338_RS11270	COG2130	NADP-dependent
S338_RS11275	COG1802	Transcriptional regulator
S338_RS11280	COG4772	TonB-dependent receptor
S338_RS11320	COG2181	nitrate reductase activity
S338_RS11325	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
S338_RS11330	COG1140	nitrate reductase beta subunit
S338_RS11335	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
S338_RS11375	COG0437	4 iron, 4 sulfur cluster binding
S338_RS11380	COG2864	formate dehydrogenase
S338_RS11385	COG1064	alcohol dehydrogenase
S338_RS11405	COG1764	response to oxidative stress
S338_RS11435	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
S338_RS11450	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
S338_RS11490	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
S338_RS11515	COG2271	Major facilitator Superfamily
S338_RS11520	COG1063	alcohol dehydrogenase
S338_RS11525	COG2186	Transcriptional regulator
S338_RS11535	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
S338_RS11540	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
S338_RS11565	COG1773	rubredoxin
S338_RS11590	COG3781	membrane
S338_RS11605	COG1012	belongs to the aldehyde dehydrogenase family
S338_RS11610	COG0583	DNA-binding transcription factor activity
S338_RS11645	COG2814	Major facilitator Superfamily
S338_RS11655	COG3111	PFAM Bacterial OB fold (BOF) protein
S338_RS11660	COG1546	Belongs to the CinA family
S338_RS11665	COG3729	General stress protein
S338_RS11680	COG4221	oxidoreductase activity
S338_RS11685	COG1802	Transcriptional regulator
S338_RS11695	COG0246	Mannitol dehydrogenase
S338_RS11700	COG0477	Major facilitator Superfamily
S338_RS11705	COG1063	alcohol dehydrogenase
S338_RS11725	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
S338_RS11740	COG0243	molybdopterin cofactor binding
S338_RS11745	COG0243	molybdopterin cofactor binding
S338_RS11750	COG0437	4 iron, 4 sulfur cluster binding
S338_RS11755	COG3302	dmso reductase anchor subunit
S338_RS11790	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
S338_RS11795	COG1940	carbohydrate kinase activity
S338_RS11800	COG0583	DNA-binding transcription factor activity
S338_RS11805	COG2814	Major facilitator Superfamily
S338_RS11815	COG3591	Belongs to the peptidase S1B family
S338_RS11835	COG0628	permease
S338_RS11840	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
S338_RS11845	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
S338_RS11855	COG0531	amino acid
S338_RS11860	COG3136	membrane protein required for alginate biosynthesis
S338_RS11865	COG0745	RESPONSE REGULATOR receiver
S338_RS11880	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
S338_RS11885	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
S338_RS11890	COG2205	protein histidine kinase activity
S338_RS11915	COG5339	Protein conserved in bacteria
S338_RS11920	COG1609	Transcriptional regulator
S338_RS11925	COG1263	PTS System
S338_RS11925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S338_RS11930	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
S338_RS11940	COG0673	inositol 2-dehydrogenase activity
S338_RS11990	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
S338_RS12000	COG0625	glutathione transferase activity
S338_RS12020	COG3895	Periplasmic Protein
S338_RS12045	COG1566	PFAM secretion protein HlyD family protein
S338_RS12060	COG4989	oxidoreductase activity
S338_RS12065	COG3313	Fe-S protein
S338_RS12070	COG1309	transcriptional regulator
S338_RS12075	COG1902	pentaerythritol trinitrate reductase activity
S338_RS12090	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
S338_RS12095	COG0791	NLP P60 protein
S338_RS12115	COG0583	DNA-binding transcription factor activity
S338_RS12120	COG2814	Major facilitator Superfamily
S338_RS12125	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
S338_RS12130	COG0307	riboflavin synthase, alpha
S338_RS12310	COG0789	Transcriptional regulator
S338_RS12315	COG3272	Protein of unknown function (DUF1722)
S338_RS12350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
S338_RS12360	COG2267	carboxylic ester hydrolase activity
S338_RS12365	COG0531	amino acid
S338_RS12380	COG1376	ErfK ybiS ycfS ynhG family protein
S338_RS12395	COG0719	Fe-S assembly protein
S338_RS12400	COG0396	ATPase activity
S338_RS12405	COG0719	Fe-S assembly protein
S338_RS12410	COG0316	Belongs to the HesB IscA family
S338_RS12415	COG1823	symporter activity
S338_RS12425	COG2050	protein possibly involved in aromatic compounds catabolism
S338_RS12430	COG0277	FAD linked oxidase domain protein
S338_RS12430	COG0247	lactate metabolic process
S338_RS12435	COG0628	permease
S338_RS12445	COG0710	3-dehydroquinate dehydratase activity
S338_RS12450	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
S338_RS12450	COG0574	Belongs to the PEP-utilizing enzyme family
S338_RS12465	COG4256	Hemin uptake protein
S338_RS12480	COG0791	NLP P60 protein
S338_RS12490	COG0386	Belongs to the glutathione peroxidase family
S338_RS12555	COG3137	Salt-induced outer membrane protein
S338_RS12560	COG1105	Belongs to the carbohydrate kinase PfkB family
S338_RS12570	COG3001	Fructosamine kinase
S338_RS12580	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
S338_RS12585	COG1988	membrane-bound metal-dependent
S338_RS12590	COG1823	symporter activity
S338_RS12600	COG0753	catalase activity
S338_RS12610	COG1486	melibiose metabolic process
S338_RS12615	COG2169	Transcriptional regulator
S338_RS12615	COG1917	Cupin 2, conserved barrel domain protein
S338_RS12620	COG1447	Phosphotransferase system cellobiose-specific component IIA
S338_RS12625	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
S338_RS12630	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
S338_RS12635	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
S338_RS12645	COG0322	excinuclease ABC activity
S338_RS12650	COG3678	ATP-independent chaperone mediated protein folding
S338_RS12685	COG0494	nUDIX hydrolase
S338_RS12700	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
S338_RS12710	COG0778	Nitroreductase
S338_RS12715	COG0616	signal peptide processing
S338_RS12720	COG0252	asparaginase activity
S338_RS12725	COG1335	isochorismatase
S338_RS12730	COG2814	Major facilitator Superfamily
S338_RS12735	COG1349	DNA-binding transcription factor activity
S338_RS12740	COG0667	Aldo Keto reductase
S338_RS12745	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
S338_RS12750	COG0191	fructose-bisphosphate aldolase activity
S338_RS12755	COG1063	alcohol dehydrogenase
S338_RS12760	COG2271	Major facilitator Superfamily
S338_RS12765	COG1063	alcohol dehydrogenase
S338_RS12775	COG3139	Protein of unknown function (DUF1315)
S338_RS12795	COG0656	L-ascorbic acid biosynthetic process
S338_RS12800	COG0641	radical SAM
S338_RS12805	COG3713	MltA-interacting MipA family protein
S338_RS12810	COG2766	serine protein kinase
S338_RS12825	COG2199	diguanylate cyclase activity
S338_RS12830	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
S338_RS12845	COG2207	Transcriptional regulator
S338_RS12850	COG2807	transmembrane transport
S338_RS12855	COG3189	MarR family transcriptional regulator
S338_RS12865	COG3042	response to heat
S338_RS12875	COG2261	transglycosylase associated protein
S338_RS12895	COG3615	Tellurite resistance protein tehB
S338_RS12905	COG1605	Chorismate mutase
S338_RS12915	COG0789	Transcriptional regulator
S338_RS12930	COG3443	Belongs to the bacterial solute-binding protein 9 family
S338_RS12945	COG0668	transmembrane transport
S338_RS12950	COG1124	(ABC) transporter
S338_RS12980	COG3038	cytochrome b561
S338_RS12990	COG0071	Belongs to the small heat shock protein (HSP20) family
S338_RS13050	COG3021	interspecies interaction between organisms
S338_RS13085	COG0538	isocitrate dehydrogenase activity
S338_RS13090	COG1403	HNH endonuclease
S338_RS13095	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
S338_RS13140	COG0538	isocitrate dehydrogenase activity
S338_RS13170	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
S338_RS13185	COG2850	peptidyl-arginine hydroxylation
S338_RS13215	COG1177	transmembrane transport
S338_RS13235	COG4591	ABC-type transport system involved in lipoprotein release permease component
S338_RS13240	COG1136	(ABC) transporter
S338_RS13245	COG4591	ABC-type transport system involved in lipoprotein release permease component
S338_RS13250	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
S338_RS13255	COG1388	LysM domain
S338_RS13255	COG1376	ErfK ybiS ycfS ynhG family protein
S338_RS13265	COG1309	transcriptional regulator
S338_RS13270	COG3134	Outer membrane lipoprotein
S338_RS13275	COG1252	NADH dehydrogenase
S338_RS13300	COG5633	Lipoprotein
S338_RS13305	COG0537	adenosine 5'-monophosphoramidase activity
S338_RS13310	COG4773	Receptor
S338_RS13320	COG0084	hydrolase, TatD family'
S338_RS13325	COG0470	DNA polymerase III
S338_RS13335	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
S338_RS13340	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
S338_RS13345	COG3539	Fimbrial protein
S338_RS13350	COG3121	Chaperone
S338_RS13375	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
S338_RS13420	COG0564	pseudouridine synthase activity
S338_RS13425	COG1530	ribonuclease E activity
S338_RS13515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
S338_RS13525	COG2999	glutathione oxidoreductase activity
S338_RS13560	COG3038	cytochrome b561
S338_RS13575	COG1560	Kdo2-lipid A biosynthetic process
S338_RS13590	COG5645	(Lipo)protein
S338_RS13595	COG2943	transferase activity, transferring hexosyl groups
S338_RS13610	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
S338_RS13665	COG3381	protein complex oligomerization
S338_RS13700	COG0673	inositol 2-dehydrogenase activity
S338_RS13705	COG2814	Major facilitator Superfamily
S338_RS13725	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
S338_RS13730	COG1737	Transcriptional regulator
S338_RS13735	COG1702	phosphate starvation-inducible protein PhoH
S338_RS13755	COG1309	transcriptional regulator
S338_RS13760	COG3729	General stress protein
S338_RS13780	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S338_RS13785	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
S338_RS13785	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
S338_RS13790	COG4232	protein-disulfide reductase activity
S338_RS13835	COG3971	2-oxopent-4-enoate hydratase activity
S338_RS13845	COG3384	dioxygenase
S338_RS13850	COG1012	belongs to the aldehyde dehydrogenase family
S338_RS13860	COG1846	Transcriptional regulator
S338_RS13865	COG2368	4-hydroxyphenylacetate
S338_RS13880	COG0745	RESPONSE REGULATOR receiver
S338_RS13885	COG2205	protein histidine kinase activity
S338_RS13930	COG0670	Belongs to the BI1 family
S338_RS13950	COG1881	PFAM PEBP family protein
S338_RS13965	COG1832	CoA-binding protein
S338_RS13980	COG0210	DNA helicase
S338_RS13985	COG3304	Inner membrane component domain
S338_RS13990	COG1289	transmembrane transporter activity
S338_RS13995	COG3070	regulator of competence-specific genes
S338_RS14015	COG1067	ATP-dependent peptidase activity
S338_RS14025	COG3130	regulation of translation
S338_RS14030	COG3009	Protein conserved in bacteria
S338_RS14035	COG3008	intermembrane lipid transfer
S338_RS14035	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
S338_RS14040	COG2995	paraquat-inducible protein a
S338_RS14045	COG0488	(ABC) transporter
S338_RS14055	COG0633	Ferredoxin
S338_RS14055	COG3217	Mosc domain protein beta barrel domain protein
S338_RS14070	COG0308	aminopeptidase N
S338_RS14080	COG0017	Asparaginyl-tRNA synthetase
S338_RS14085	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
S338_RS14095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
S338_RS14100	COG3108	Peptidase M15
S338_RS14105	COG2989	Protein conserved in bacteria
S338_RS14115	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
S338_RS14125	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
S338_RS14130	COG1434	Gram-negative-bacterium-type cell wall biogenesis
S338_RS14135	COG3173	Aminoglycoside phosphotransferase
S338_RS14150	COG3214	Protein conserved in bacteria
S338_RS14165	COG0658	competence protein
S338_RS14165	COG2333	competence protein COMEC
S338_RS14175	COG0539	negative regulation of cytoplasmic translation
S338_RS14185	COG0501	Belongs to the peptidase M48B family
S338_RS14200	COG2323	membrane
S338_RS14205	COG1944	ATP diphosphatase activity
S338_RS14210	COG2116	formate transmembrane transporter activity
S338_RS14215	COG1882	Formate acetyltransferase
S338_RS14225	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
S338_RS14230	COG0531	amino acid
S338_RS14240	COG3302	dmso reductase anchor subunit
S338_RS14245	COG0437	4 iron, 4 sulfur cluster binding
S338_RS14250	COG0243	molybdopterin cofactor binding
S338_RS14260	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
S338_RS14280	COG0492	ferredoxin-NADP+ reductase activity
S338_RS14285	COG4988	ABC transporter
S338_RS14290	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
S338_RS14310	COG0583	DNA-binding transcription factor activity
S338_RS14320	COG1335	isochorismatase
S338_RS14335	COG0542	response to heat
S338_RS14345	COG1278	Cold shock
S338_RS14350	COG0577	efflux transmembrane transporter activity
S338_RS14350	COG1136	(ABC) transporter
S338_RS14355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
S338_RS14360	COG2990	Protein conserved in bacteria
S338_RS14365	COG3593	DNA synthesis involved in DNA repair
S338_RS14370	COG2431	L-lysine efflux transmembrane transporter activity
S338_RS14380	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
S338_RS14385	COG0028	Belongs to the TPP enzyme family
S338_RS14390	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
S338_RS14395	COG0702	epimerase
S338_RS14400	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
S338_RS14405	COG3023	N-Acetylmuramoyl-L-alanine amidase
S338_RS14420	COG1126	abc transporter atp-binding protein
S338_RS14425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
S338_RS14430	COG4215	(ABC) transporter
S338_RS14435	COG4160	amino acid transport
S338_RS14440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
S338_RS14470	COG1177	transmembrane transport
S338_RS14475	COG1176	ABC-type spermidine putrescine transport system, permease component I
S338_RS14480	COG3842	ATPase activity
S338_RS14485	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
S338_RS14530	COG3226	Transcriptional regulator
S338_RS14535	COG0738	Major facilitator superfamily
S338_RS14540	COG0561	phosphatase activity
S338_RS14545	COG2814	Major facilitator Superfamily
S338_RS14555	COG0671	phosphoesterase, PA-phosphatase related
S338_RS14560	COG1349	DNA-binding transcription factor activity
S338_RS14565	COG1686	Belongs to the peptidase S11 family
S338_RS14570	COG0625	glutathione transferase activity
S338_RS14575	COG2133	pyrroloquinoline quinone binding
S338_RS14580	COG2610	gluconate transmembrane transporter activity
S338_RS14585	COG0583	DNA-binding transcription factor activity
S338_RS14595	COG1960	acyl-CoA dehydrogenase activity
S338_RS14600	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
S338_RS14615	COG2301	Belongs to the HpcH HpaI aldolase family
S338_RS14640	COG0747	negative chemotaxis
S338_RS14665	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
S338_RS14670	COG1882	Formate acetyltransferase
S338_RS14675	COG0561	phosphatase activity
S338_RS14685	COG0488	(ABC) transporter
S338_RS14690	COG1376	ErfK ybiS ycfS ynhG family protein
S338_RS14695	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
S338_RS14710	COG2194	sulfuric ester hydrolase activity
S338_RS14715	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
S338_RS14730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
S338_RS14735	COG0765	amino acid transport
S338_RS14740	COG1126	abc transporter atp-binding protein
S338_RS14745	COG0668	transmembrane transport
S338_RS14755	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
S338_RS14765	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
S338_RS14775	COG0513	Belongs to the DEAD box helicase family
S338_RS14780	COG1309	transcriptional regulator
S338_RS14790	COG1131	(ABC) transporter
S338_RS14795	COG0842	Transport permease protein
S338_RS14800	COG0842	Transport permease protein
S338_RS14810	COG3568	Endonuclease Exonuclease Phosphatase
S338_RS14815	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
S338_RS14820	COG0392	lysyltransferase activity
S338_RS14835	COG0670	Belongs to the BI1 family
S338_RS14845	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
S338_RS14855	COG0521	Mo-molybdopterin cofactor biosynthetic process
S338_RS14915	COG1881	PFAM PEBP family protein
S338_RS15040	COG3646	Phage regulatory protein
S338_RS15060	COG0484	heat shock protein binding
S338_RS15175	COG4712	double-strand break repair protein
S338_RS15240	COG0582	viral genome integration into host DNA
S338_RS15245	COG4677	pectinesterase activity
S338_RS15255	COG0561	phosphatase activity
S338_RS15265	COG4149	molybdate abc transporter
S338_RS15270	COG0725	ABC transporter, periplasmic molybdate-binding protein
S338_RS15280	COG3585	molybdate ion transport
S338_RS15280	COG2005	Transcriptional regulator
S338_RS15285	COG1119	ATPase activity
S338_RS15310	COG2017	converts alpha-aldose to the beta-anomer
S338_RS15320	COG1120	ATPase activity
S338_RS15325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S338_RS15330	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
S338_RS15340	COG1230	cation diffusion facilitator family transporter
S338_RS15395	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
S338_RS15400	COG2885	chlorophyll binding
S338_RS15410	COG3064	Membrane
S338_RS15415	COG0848	biopolymer transport protein
S338_RS15420	COG0811	peptide transport
S338_RS15425	COG0824	Thioesterase
S338_RS15430	COG3790	cyd operon protein YbgE
S338_RS15435	COG4890	Cyd operon protein YbgT
S338_RS15440	COG1294	oxidase, subunit
S338_RS15445	COG1271	oxidase subunit
S338_RS15450	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
S338_RS15460	COG0508	dehydrogenase complex catalyzes the overall conversion of
S338_RS15465	COG0567	Dehydrogenase, E1 component
S338_RS15480	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
S338_RS15495	COG3180	Ammonia monooxygenase
S338_RS15510	COG1984	allophanate hydrolase subunit 2
S338_RS15515	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
S338_RS15560	COG2205	protein histidine kinase activity
S338_RS15565	COG0745	RESPONSE REGULATOR receiver
S338_RS15575	COG1982	Orn Lys Arg decarboxylase major
S338_RS15580	COG0531	amino acid
S338_RS15590	COG0033	Phosphoglucomutase
S338_RS15600	COG0596	Alpha beta hydrolase
S338_RS15615	COG0735	belongs to the Fur family
S338_RS15620	COG0583	DNA-binding transcription factor activity
S338_RS15625	COG1053	succinate dehydrogenase
S338_RS15665	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
S338_RS15670	COG1846	Transcriptional regulator
S338_RS15670	COG1940	carbohydrate kinase activity
S338_RS15675	COG0647	UMP catabolic process
S338_RS15680	COG0367	asparagine synthase
S338_RS15720	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
S338_RS15730	COG1702	phosphate starvation-inducible protein PhoH
S338_RS15755	COG0765	amino acid transport
S338_RS15760	COG0765	amino acid transport
S338_RS15765	COG1126	abc transporter atp-binding protein
S338_RS15775	COG2888	peptidyl-tyrosine sulfation
S338_RS15780	COG3290	protein histidine kinase activity
S338_RS15780	COG3829	transcription factor binding
S338_RS15810	COG1466	dna polymerase III delta subunit
S338_RS15820	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
S338_RS15830	COG0799	negative regulation of ribosome biogenesis
S338_RS15840	COG0768	penicillin binding
S338_RS15845	COG0772	Belongs to the SEDS family
S338_RS15855	COG1686	Belongs to the peptidase S11 family
S338_RS15870	COG0583	DNA-binding transcription factor activity
S338_RS15885	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
S338_RS15905	COG3069	C4-dicarboxylate transmembrane transporter activity
S338_RS15910	COG4565	transcriptional regulatory protein
S338_RS15915	COG3290	protein histidine kinase activity
S338_RS15920	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
S338_RS15930	COG2301	Belongs to the HpcH HpaI aldolase family
S338_RS15935	COG3051	citrate lyase alpha subunit
S338_RS15945	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
S338_RS15950	COG0471	metal ion transport
S338_RS15955	COG3719	Belongs to the RNase T2 family
S338_RS15960	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
S338_RS15965	COG1063	alcohol dehydrogenase
S338_RS15985	COG0243	molybdopterin cofactor binding
S338_RS16005	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
S338_RS16010	COG0583	DNA-binding transcription factor activity
S338_RS16015	COG3969	phosphoadenosine phosphosulfate
S338_RS16020	COG1475	DNA binding
S338_RS16025	COG0436	Aminotransferase
S338_RS16030	COG0371	Dehydrogenase
S338_RS16035	COG2879	small protein
S338_RS16040	COG1966	Carbon starvation protein
S338_RS16050	COG1028	Short-chain dehydrogenase reductase Sdr
S338_RS16055	COG1535	isochorismatase
S338_RS16055	COG3433	isochorismatase activity
S338_RS16060	COG1021	2,3-dihydroxybenzoate-AMP ligase
S338_RS16065	COG1169	isochorismate synthase
S338_RS16070	COG4592	Periplasmic binding protein
S338_RS16080	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S338_RS16085	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S338_RS16090	COG1120	ATPase activity
S338_RS16095	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
S338_RS16100	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S338_RS16100	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
S338_RS16105	COG3251	PFAM MbtH domain protein
S338_RS16110	COG2382	esterase
S338_RS16115	COG4771	TonB-dependent receptor
S338_RS16120	COG2977	Belongs to the P-Pant transferase superfamily
S338_RS16145	COG2315	Protein conserved in bacteria
S338_RS16160	COG0668	transmembrane transport
S338_RS16165	COG1113	amino acid transport
S338_RS16175	COG3059	membrane
S338_RS16185	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
S338_RS16190	COG2207	Transcriptional regulator
S338_RS16200	COG5002	protein histidine kinase activity
S338_RS16210	COG2246	polysaccharide biosynthetic process
S338_RS16215	COG0463	Glycosyl transferase, family 2
S338_RS16240	COG0463	Glycosyl transferase, family 2
S338_RS16245	COG2246	polysaccharide biosynthetic process
S338_RS16335	COG2501	S4 domain
S338_RS16340	COG1988	membrane-bound metal-dependent
S338_RS16360	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
S338_RS16370	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
S338_RS16375	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
S338_RS16395	COG1464	Belongs to the NlpA lipoprotein family
S338_RS16405	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
S338_RS16410	COG4181	ATPase activity
S338_RS16415	COG2755	lipolytic protein G-D-S-L family
S338_RS16420	COG0300	oxidoreductase activity
S338_RS16425	COG3118	belongs to the thioredoxin family
S338_RS16430	COG0390	transport system, permease component
S338_RS16435	COG4619	ABC transporter
S338_RS16440	COG0330	HflC and HflK could
S338_RS16445	COG1585	Membrane protein implicated in regulation of membrane protease activity
S338_RS16455	COG2217	Heavy metal translocating P-type atpase
S338_RS16465	COG3735	TraB family
S338_RS16480	COG2223	nitrite transmembrane transporter activity
S338_RS16485	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
S338_RS16485	COG4651	solute:proton antiporter activity
S338_RS16490	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
S338_RS16535	COG2832	Protein of unknown function (DUF454)
S338_RS16540	COG3923	Primosomal replication protein n
S338_RS16550	COG5464	transposase or invertase
S338_RS16555	COG1196	nuclear chromosome segregation
S338_RS16555	COG3264	Mechanosensitive ion channel
S338_RS16560	COG1309	transcriptional regulator
S338_RS16565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
S338_RS16570	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
S338_RS16585	COG0110	maltose O-acetyltransferase activity
S338_RS16605	COG4943	cyclic-guanylate-specific phosphodiesterase activity
S338_RS16615	COG3695	enzyme binding
S338_RS16620	COG3126	Type III secretion system lipoprotein chaperone (YscW)
S338_RS16625	COG1946	Acyl-CoA thioesterase
S338_RS16630	COG0004	ammonium transporteR
S338_RS16635	COG0347	Belongs to the P(II) protein family
S338_RS16640	COG1132	(ABC) transporter
S338_RS16645	COG1132	(ABC) transporter
S338_RS16650	COG1522	sequence-specific DNA binding
S338_RS16665	COG4533	DNA binding
S338_RS16675	COG0824	Thioesterase
S338_RS16680	COG1555	photosystem II stabilization
S338_RS16685	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
S338_RS16695	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
S338_RS16730	COG0271	Belongs to the BolA IbaG family
S338_RS16735	COG3056	Lipoprotein
S338_RS16740	COG2223	nitrite transmembrane transporter activity
S338_RS16745	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
S338_RS16750	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
S338_RS16755	COG1845	cytochrome c oxidase, subunit III
S338_RS16760	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
S338_RS16770	COG2814	Major facilitator Superfamily
S338_RS16800	COG2188	Transcriptional regulator
S338_RS16810	COG3842	ATPase activity
S338_RS16835	COG0142	geranyltranstransferase activity
S338_RS16845	COG0667	Aldo Keto reductase
S338_RS16850	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
S338_RS16870	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
S338_RS16870	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
S338_RS16880	COG4238	major outer membrane lipoprotein
S338_RS16910	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
S338_RS16920	COG1862	Preprotein translocase
S338_RS16940	COG0450	alkyl hydroperoxide reductase
S338_RS16950	COG0366	Alpha amylase catalytic
S338_RS16965	COG5002	protein histidine kinase activity
S338_RS16975	COG0420	3'-5' exonuclease activity
S338_RS16980	COG0419	ATPase involved in DNA repair
S338_RS16985	COG2814	Major facilitator Superfamily
S338_RS16990	COG1940	carbohydrate kinase activity
S338_RS17005	COG4126	flavin adenine dinucleotide binding
S338_RS17025	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
S338_RS17080	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
S338_RS17085	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
S338_RS17100	COG0113	porphobilinogen synthase activity
S338_RS17135	COG1280	lysine exporter protein (LysE YggA)
S338_RS17155	COG1294	oxidase, subunit
S338_RS17160	COG1271	oxidase subunit
S338_RS17180	COG2814	Major facilitator Superfamily
S338_RS17190	COG0789	Transcriptional regulator
S338_RS17245	COG2200	EAL domain
S338_RS17260	COG3539	Fimbrial protein
S338_RS17265	COG3121	Chaperone
S338_RS17270	COG3188	usher protein
S338_RS17325	COG2195	Cleaves the N-terminal amino acid of tripeptides
S338_RS17330	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
S338_RS17335	COG1690	Belongs to the RtcB family
S338_RS17345	COG3034	peptidoglycan biosynthetic process
S338_RS17350	COG0121	glutamine amidotransferase
S338_RS17365	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
S338_RS17395	COG1522	sequence-specific DNA binding
S338_RS17490	COG3209	COG3209 Rhs family protein
S338_RS17545	COG2885	chlorophyll binding
S338_RS17545	COG3047	cAMP biosynthetic process
S338_RS17660	COG2226	methyltransferase
S338_RS17670	COG0741	lytic transglycosylase activity
S338_RS17670	COG1388	LysM domain
S338_RS17675	COG2226	methyltransferase
S338_RS17685	COG2814	Major facilitator Superfamily
S338_RS17690	COG0583	DNA-binding transcription factor activity
S338_RS17695	COG0656	L-ascorbic acid biosynthetic process
S338_RS17740	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
S338_RS17765	COG1720	tRNA m6t6A37 methyltransferase activity
S338_RS17775	COG3015	lipoprotein NlpE involved in copper resistance
S338_RS17780	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
S338_RS17795	COG4568	rho-dependent transcription termination
S338_RS17805	COG0346	lactoylglutathione lyase activity
S338_RS17810	COG1982	Orn Lys Arg decarboxylase major
S338_RS17870	COG0575	Belongs to the CDS family
S338_RS17920	COG0477	Major facilitator Superfamily
S338_RS17935	COG3835	regulator
S338_RS17960	COG2860	membrane
S338_RS17985	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
S338_RS17990	COG1120	ATPase activity
S338_RS17995	COG4774	siderophore transport
S338_RS18000	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
S338_RS18005	COG1643	Atp-dependent helicase
S338_RS18010	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
S338_RS18030	COG0617	tRNA 3'-terminal CCA addition
S338_RS18035	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
S338_RS18045	COG3121	Chaperone
S338_RS18050	COG3188	usher protein
S338_RS18055	COG3539	Fimbrial protein
S338_RS18060	COG3539	Fimbrial protein
S338_RS18065	COG3539	Fimbrial protein
S338_RS18070	COG3539	Fimbrial protein
S338_RS18075	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
S338_RS18090	COG0726	polysaccharide deacetylase
S338_RS18095	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
S338_RS18120	COG3539	Fimbrial protein
S338_RS18125	COG0842	Transport permease protein
S338_RS18130	COG1131	(ABC) transporter
S338_RS18135	COG0288	reversible hydration of carbon dioxide
S338_RS18145	COG4993	Dehydrogenase
S338_RS18170	COG1349	DNA-binding transcription factor activity
S338_RS18200	COG3064	Membrane
S338_RS18215	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
S338_RS18220	COG0508	dehydrogenase complex catalyzes the overall conversion of
S338_RS18225	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
S338_RS18240	COG2211	Major facilitator Superfamily
S338_RS18245	COG3940	Belongs to the glycosyl hydrolase 43 family
S338_RS18250	COG3725	Membrane protein required for beta-lactamase induction
S338_RS18265	COG4969	Belongs to the N-Me-Phe pilin family
S338_RS18270	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
S338_RS18275	COG1459	type II secretion system
S338_RS18305	COG0494	nUDIX hydrolase
S338_RS18325	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
S338_RS18330	COG0849	cell division
S338_RS18355	COG0772	Belongs to the SEDS family
S338_RS18370	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
S338_RS18380	COG0768	penicillin binding
S338_RS18410	COG0028	Belongs to the TPP enzyme family
S338_RS18465	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
S338_RS18470	COG0586	Pfam SNARE associated Golgi protein
S338_RS18510	COG0417	DNA replication proofreading
S338_RS18530	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
S338_RS18540	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
S338_RS18575	COG3119	arylsulfatase activity
S338_RS18595	COG2271	Major facilitator Superfamily
S338_RS18605	COG0644	oxidoreductase
S338_RS18630	COG1804	L-carnitine dehydratase bile acid-inducible protein F
S338_RS18760	COG1047	Peptidyl-prolyl cis-trans
S338_RS18775	COG0196	riboflavin kinase activity
S338_RS18800	COG0583	DNA-binding transcription factor activity
S338_RS18825	COG0641	radical SAM
S338_RS18830	COG3119	arylsulfatase activity
S338_RS18865	COG3121	Chaperone
S338_RS18870	COG3539	Fimbrial protein
S338_RS18885	COG3188	usher protein
S338_RS18950	COG4735	regulation of single-species biofilm formation
S338_RS18955	COG1584	GPR1 FUN34 yaaH family protein
S338_RS18960	COG0521	Mo-molybdopterin cofactor biosynthetic process
S338_RS18970	COG1115	amino acid carrier protein
S338_RS18980	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
S338_RS18990	COG0527	aspartate kinase activity
S338_RS18990	COG0460	homoserine dehydrogenase
S338_RS19000	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
S338_RS19010	COG0745	RESPONSE REGULATOR receiver
S338_RS19030	COG3121	Chaperone
S338_RS19050	COG4452	Inner membrane protein CreD
S338_RS19055	COG2205	protein histidine kinase activity
S338_RS19060	COG0745	RESPONSE REGULATOR receiver
S338_RS19065	COG3045	CreA protein
S338_RS19070	COG3708	Transcriptional regulator
S338_RS19070	COG2207	Transcriptional regulator
S338_RS19095	COG0488	(ABC) transporter
S338_RS19110	COG0560	Phosphoserine phosphatase
S338_RS19115	COG3726	membrane protein affecting hemolysin expression
S338_RS19130	COG3539	Fimbrial protein
S338_RS19135	COG3121	Chaperone
S338_RS19140	COG3188	usher protein
S338_RS19170	COG1328	CTP reductase activity
S338_RS19175	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
S338_RS19180	COG0084	hydrolase, TatD family'
S338_RS19185	COG4667	esterase of the alpha-beta hydrolase superfamily
S338_RS19195	COG2823	Periplasmic or secreted lipoprotein
S338_RS19205	COG1011	Hydrolase
S338_RS19215	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
S338_RS19245	COG3706	GGDEF domain
S338_RS19250	COG4114	ferric iron reductase
S338_RS19255	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
S338_RS19260	COG2197	response regulator
S338_RS19265	COG2197	response regulator
S338_RS19270	COG2966	Psort location CytoplasmicMembrane, score
S338_RS19285	COG1484	DNA-dependent DNA replication
S338_RS19305	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
S338_RS19310	COG3716	PTS system mannose fructose sorbose family IID component
S338_RS19315	COG3715	PTS system
S338_RS19320	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S338_RS19335	COG0840	transmembrane signaling receptor activity
S338_RS19340	COG1966	Carbon starvation protein
S338_RS19345	COG2879	small protein
S338_RS19350	COG0523	cobalamin synthesis protein
S338_RS19370	COG0732	type I restriction modification DNA specificity domain
S338_RS19385	COG3586	endonuclease activity
S338_RS19400	COG1012	belongs to the aldehyde dehydrogenase family
S338_RS19405	COG5464	transposase or invertase
S338_RS19415	COG2733	membrane
S338_RS19420	COG0477	Major facilitator Superfamily
S338_RS19430	COG3366	ferrous iron transmembrane transporter activity
S338_RS19435	COG0700	Nucleoside recognition
S338_RS19440	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
S338_RS19445	COG0583	DNA-binding transcription factor activity
S338_RS19465	COG2186	Transcriptional regulator
S338_RS19470	COG0412	Dienelactone hydrolase
S338_RS19495	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
S338_RS19520	COG0720	synthase
S338_RS19555	COG0514	ATP-dependent DNA helicase (RecQ)
S338_RS19560	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
S338_RS19610	COG1064	alcohol dehydrogenase
S338_RS19615	COG3265	gluconokinase activity
S338_RS19620	COG1063	alcohol dehydrogenase
S338_RS19625	COG1028	Short-chain dehydrogenase reductase Sdr
S338_RS19630	COG2610	gluconate transmembrane transporter activity
S338_RS19635	COG1609	Transcriptional regulator
S338_RS19640	COG0795	lipopolysaccharide-transporting ATPase activity
S338_RS19645	COG0795	lipopolysaccharide-transporting ATPase activity
S338_RS19655	COG2927	DNA polymerase III (CHI subunit)
S338_RS19695	COG2731	YhcH YjgK YiaL family protein
S338_RS19715	COG1288	antiporter activity
S338_RS19720	COG1438	arginine binding
S338_RS19770	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S338_RS19770	COG1263	PTS System
S338_RS19775	COG0366	Alpha amylase catalytic
S338_RS19790	COG2026	Addiction module toxin, RelE StbE family
S338_RS19795	COG3077	Addiction module antitoxin, RelB DinJ family
S338_RS19800	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
S338_RS19800	COG3711	transcriptional antiterminator
S338_RS19815	COG3964	amidohydrolase
S338_RS19850	COG0312	modulator of DNA gyrase
S338_RS19860	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
S338_RS19875	COG3964	amidohydrolase
S338_RS19880	COG2271	Major facilitator Superfamily
S338_RS19885	COG2105	PFAM AIG2 family protein
S338_RS19905	COG1253	flavin adenine dinucleotide binding
S338_RS19915	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
S338_RS19930	COG1733	regulation of RNA biosynthetic process
S338_RS19935	COG0702	epimerase
S338_RS19940	COG0697	spore germination
S338_RS19950	COG1113	amino acid transport
S338_RS19955	COG0545	Peptidyl-prolyl cis-trans isomerase
S338_RS19960	COG3061	Opacity-associated protein A
S338_RS19975	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
S338_RS19995	COG3477	response to acidic pH
S338_RS20025	COG3037	sugar-specific permease SgaT UlaA
S338_RS20040	COG1073	alpha beta
S338_RS20045	COG3650	response to hydrogen peroxide
S338_RS20055	COG1960	acyl-CoA dehydrogenase activity
S338_RS20060	COG0754	glutathionylspermidine amidase activity
S338_RS20065	COG5463	Belongs to the UPF0441 family
S338_RS20070	COG3766	membrane
S338_RS20080	COG1842	Phage shock protein A
S338_RS20085	COG3789	protein conserved in bacteria
S338_RS20095	COG0557	exoribonuclease II activity
S338_RS20110	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
S338_RS20115	COG0330	HflC and HflK could
S338_RS20120	COG0330	HflC and HflK could
S338_RS20125	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
S338_RS20150	COG0802	atpase or kinase
S338_RS20155	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
S338_RS20155	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
S338_RS20180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
S338_RS20200	COG1511	domain protein
S338_RS20200	COG3264	Mechanosensitive ion channel
S338_RS20215	COG1053	succinate dehydrogenase
S338_RS20220	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
S338_RS20250	COG5510	response to toxic substance
S338_RS20290	COG0531	amino acid
S338_RS20295	COG3030	protein affecting phage T7 exclusion by the F plasmid
S338_RS20300	COG1027	Aspartate ammonia-lyase
S338_RS20305	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
S338_RS20320	COG1309	transcriptional regulator
S338_RS20335	COG0671	phosphoesterase, PA-phosphatase related
S338_RS20430	COG2197	response regulator
S338_RS20450	COG3381	protein complex oligomerization
S338_RS20455	COG3302	dmso reductase anchor subunit
S338_RS20460	COG0437	4 iron, 4 sulfur cluster binding
S338_RS20465	COG0243	molybdopterin cofactor binding
S338_RS20470	COG3290	protein histidine kinase activity
S338_RS20475	COG4565	transcriptional regulatory protein
S338_RS20485	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
S338_RS20490	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
S338_RS20490	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
S338_RS20505	COG2169	Transcriptional regulator
S338_RS20510	COG1982	Orn Lys Arg decarboxylase major
S338_RS20515	COG2207	Transcriptional regulator
S338_RS20520	COG0531	amino acid
S338_RS20550	COG2824	Alkylphosphonate utilization operon protein PhnA
S338_RS20555	COG2764	glyoxalase bleomycin resistance protein dioxygenase
S338_RS20575	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
S338_RS20580	COG1301	dicarboxylic acid transport
S338_RS20585	COG4235	cytochrome complex assembly
S338_RS20590	COG3088	subunit of a heme lyase
S338_RS20595	COG1138	Cytochrome C-type biogenesis protein
S338_RS20600	COG3301	Polysulphide reductase, NrfD
S338_RS20605	COG0437	4 iron, 4 sulfur cluster binding
S338_RS20610	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
S338_RS20620	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
S338_RS20625	COG3162	membrane
S338_RS20635	COG1346	cytolysis
S338_RS20640	COG1380	Effector of murein hydrolase LrgA
S338_RS20645	COG0583	DNA-binding transcription factor activity
S338_RS20650	COG0025	NhaP-type Na H and K H
S338_RS20655	COG2252	PERMEase
S338_RS20675	COG4943	cyclic-guanylate-specific phosphodiesterase activity
S338_RS20740	COG2315	Protein conserved in bacteria
S338_RS20750	COG3700	Belongs to the class B bacterial acid phosphatase family
S338_RS20780	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
S338_RS20790	COG0735	belongs to the Fur family
S338_RS20805	COG0534	Mate efflux family protein
S338_RS20815	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
S338_RS20860	COG3833	ABC-type maltose transport systems, permease component
S338_RS20865	COG0477	Major facilitator Superfamily
S338_RS20865	COG2814	Major facilitator Superfamily
S338_RS20875	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
S338_RS20900	COG0527	aspartate kinase activity
S338_RS20915	COG0561	phosphatase activity
S338_RS20920	COG1349	DNA-binding transcription factor activity
S338_RS20935	COG3122	Protein conserved in bacteria
S338_RS20980	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
S338_RS21020	COG0151	Belongs to the GarS family
S338_RS21085	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
S338_RS21090	COG2104	thiamine diphosphate biosynthetic process
S338_RS21160	COG0250	Participates in transcription elongation, termination and antitermination
S338_RS21270	COG0583	DNA-binding transcription factor activity
S338_RS21305	COG2207	Transcriptional regulator
S338_RS21315	COG0371	Dehydrogenase
S338_RS21330	COG0737	Belongs to the 5'-nucleotidase family
S338_RS21345	COG0527	aspartate kinase activity
S338_RS21345	COG0460	homoserine dehydrogenase
S338_RS21350	COG0626	cystathionine gamma-synthase activity
S338_RS21375	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
S338_RS21380	COG1609	Transcriptional regulator
S338_RS21385	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
S338_RS21400	COG1575	Belongs to the MenA family. Type 1 subfamily
S338_RS21415	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
S338_RS21425	COG1494	fructose-1,6-bisphosphatase
S338_RS21435	COG3152	Membrane
S338_RS21490	COG1070	Carbohydrate kinase
S338_RS21510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
S338_RS21520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
S338_RS21525	COG2211	Major facilitator Superfamily
S338_RS21550	COG3678	ATP-independent chaperone mediated protein folding
S338_RS21555	COG0745	RESPONSE REGULATOR receiver
S338_RS21560	COG2205	protein histidine kinase activity
S338_RS21570	COG2258	MOSC domain
S338_RS21575	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
S338_RS21585	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
S338_RS21630	COG1454	alcohol dehydrogenase
S338_RS21645	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
S338_RS21670	COG0437	4 iron, 4 sulfur cluster binding
S338_RS21675	COG2864	formate dehydrogenase
S338_RS21690	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
S338_RS21700	COG4680	protein conserved in bacteria
S338_RS21705	COG5499	transcription regulator containing HTH domain
S338_RS21710	COG0456	acetyltransferase
S338_RS21725	COG1011	Hydrolase
S338_RS21730	COG1349	DNA-binding transcription factor activity
S338_RS21735	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
S338_RS21745	COG3684	Belongs to the aldolase LacD family
S338_RS21755	COG2017	converts alpha-aldose to the beta-anomer
S338_RS21760	COG1501	Belongs to the glycosyl hydrolase 31 family
S338_RS21835	COG0204	Acyl-transferase
S338_RS21850	COG3084	Protein conserved in bacteria
S338_RS21855	COG0746	molybdenum cofactor guanylyltransferase activity
S338_RS21860	COG1763	Mo-molybdopterin cofactor biosynthetic process
S338_RS21905	COG1739	Uncharacterized protein family UPF0029
S338_RS21935	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
S338_RS21950	COG0805	protein transport
S338_RS21995	COG0641	radical SAM
S338_RS22020	COG0561	phosphatase activity
S338_RS22025	COG2267	carboxylic ester hydrolase activity
S338_RS22030	COG1280	lysine exporter protein (LysE YggA)
S338_RS22035	COG1280	lysine exporter protein (LysE YggA)
S338_RS22070	COG1011	Hydrolase
S338_RS22075	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
S338_RS22140	COG2959	enzyme of heme biosynthesis
S338_RS22145	COG3071	HemY protein
S338_RS22200	COG2244	polysaccharide biosynthetic process
S338_RS22205	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
S338_RS22210	COG0456	acetyltransferase
S338_RS22215	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
S338_RS22220	COG1088	dTDP-glucose 4,6-dehydratase activity
S338_RS22225	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
S338_RS22240	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
S338_RS22260	COG3118	belongs to the thioredoxin family
S338_RS22340	COG3978	acetolactate synthase activity
S338_RS22400	COG2186	Transcriptional regulator
S338_RS22405	COG0477	Major facilitator Superfamily
S338_RS22410	COG1609	Transcriptional regulator
S338_RS22415	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
S338_RS22425	COG1172	Belongs to the binding-protein-dependent transport system permease family
S338_RS22460	COG1522	sequence-specific DNA binding
S338_RS22465	COG0716	FMN binding
S338_RS22480	COG3312	ion transport
S338_RS22540	COG4533	DNA binding
S338_RS22545	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
S338_RS22550	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
S338_RS22550	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
S338_RS22550	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
S338_RS22555	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
S338_RS22560	COG0573	inorganic phosphate transmembrane transporter activity
S338_RS22565	COG0581	inorganic phosphate transmembrane transporter activity
S338_RS22575	COG0704	Plays a role in the regulation of phosphate uptake
S338_RS22580	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
S338_RS22585	COG2252	PERMEase
S338_RS22590	COG0431	NADPH-dependent FMN reductase
S338_RS22595	COG2091	lysine biosynthetic process via aminoadipic acid