locus-tag	class	description
I6I24_RS00055	COG3850	Histidine kinase
I6I24_RS00060	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
I6I24_RS00070	COG1393	Belongs to the ArsC family
I6I24_RS00090	COG2321	neutral zinc metallopeptidase
I6I24_RS00100	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
I6I24_RS00110	COG2716	regulation of RNA biosynthetic process
I6I24_RS00115	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
I6I24_RS00125	COG0628	permease
I6I24_RS00135	COG1393	Belongs to the ArsC family
I6I24_RS00145	COG2233	PERMEase
I6I24_RS00160	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
I6I24_RS00175	COG2200	EAL domain
I6I24_RS00210	COG0517	IMP dehydrogenase activity
I6I24_RS00210	COG0516	GMP reductase activity
I6I24_RS00250	COG1645	bacterial-type flagellum-dependent swarming motility
I6I24_RS00265	COG2976	Protein conserved in bacteria
I6I24_RS00305	COG0437	4 iron, 4 sulfur cluster binding
I6I24_RS00310	COG0243	molybdopterin cofactor binding
I6I24_RS00315	COG4953	penicillin-binding protein 1C
I6I24_RS00320	COG2373	Large extracellular alpha-helical protein
I6I24_RS00325	COG2897	thiosulfate sulfurtransferase activity
I6I24_RS00345	COG2975	iron-sulfur cluster assembly
I6I24_RS00350	COG0633	Ferredoxin
I6I24_RS00370	COG0822	iron-sulfur transferase activity
I6I24_RS00415	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
I6I24_RS00425	COG3711	transcriptional antiterminator
I6I24_RS00430	COG2814	Major facilitator Superfamily
I6I24_RS00440	COG1017	nitric oxide dioxygenase activity
I6I24_RS00440	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
I6I24_RS00445	COG3710	Transcriptional regulator
I6I24_RS00450	COG0531	amino acid
I6I24_RS00460	COG3104	oligopeptide transport
I6I24_RS00465	COG0347	Belongs to the P(II) protein family
I6I24_RS00470	COG2204	response regulator
I6I24_RS00475	COG3170	Tfp pilus assembly protein FimV
I6I24_RS00480	COG2205	protein histidine kinase activity
I6I24_RS00505	COG0560	Phosphoserine phosphatase
I6I24_RS00510	COG1263	PTS System
I6I24_RS00510	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I6I24_RS00520	COG1737	Transcriptional regulator
I6I24_RS00525	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
I6I24_RS00530	COG2223	nitrite transmembrane transporter activity
I6I24_RS00535	COG0583	DNA-binding transcription factor activity
I6I24_RS00540	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
I6I24_RS00605	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
I6I24_RS00625	COG5301	cellulose 1,4-beta-cellobiosidase activity
I6I24_RS00735	COG4220	transposase activity
I6I24_RS00870	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
I6I24_RS00895	COG3086	response to oxidative stress
I6I24_RS00930	COG0513	Belongs to the DEAD box helicase family
I6I24_RS00935	COG0583	DNA-binding transcription factor activity
I6I24_RS00955	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
I6I24_RS00960	COG3118	belongs to the thioredoxin family
I6I24_RS00965	COG3148	PFAM DTW domain containing protein
I6I24_RS00975	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
I6I24_RS00980	COG5544	Lipoprotein
I6I24_RS00985	COG0477	Major facilitator Superfamily
I6I24_RS01015	COG0542	response to heat
I6I24_RS01030	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
I6I24_RS01035	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
I6I24_RS01045	COG0077	Prephenate dehydratase
I6I24_RS01045	COG1605	Chorismate mutase
I6I24_RS01055	COG1605	Chorismate mutase
I6I24_RS01055	COG0287	Prephenate dehydrogenase
I6I24_RS01070	COG2199	diguanylate cyclase activity
I6I24_RS01115	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
I6I24_RS01170	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
I6I24_RS01175	COG4137	Cytochrome C assembly protein
I6I24_RS01180	COG4536	flavin adenine dinucleotide binding
I6I24_RS01200	COG0497	DNA recombination
I6I24_RS01215	COG2867	negative regulation of translational initiation
I6I24_RS01240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
I6I24_RS01390	COG4695	Portal protein
I6I24_RS01400	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
I6I24_RS01475	COG4974	Belongs to the 'phage' integrase family
I6I24_RS01485	COG0582	viral genome integration into host DNA
I6I24_RS01580	COG4133	protoheme IX ABC transporter activity
I6I24_RS01595	COG3423	Transcriptional regulator
I6I24_RS01615	COG0673	inositol 2-dehydrogenase activity
I6I24_RS01625	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
I6I24_RS01630	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
I6I24_RS01640	COG1263	PTS System
I6I24_RS01640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I6I24_RS01640	COG2190	(PTS) system
I6I24_RS01665	COG0582	viral genome integration into host DNA
I6I24_RS01720	COG2819	hydrolase of the alpha beta superfamily
I6I24_RS01740	COG2990	Protein conserved in bacteria
I6I24_RS01750	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
I6I24_RS01785	COG0579	oxidoreductase
I6I24_RS01790	COG1012	belongs to the aldehyde dehydrogenase family
I6I24_RS01795	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
I6I24_RS01800	COG1113	amino acid transport
I6I24_RS01805	COG1802	Transcriptional regulator
I6I24_RS01810	COG1652	LysM domain
I6I24_RS01815	COG0401	homolog of Blt101
I6I24_RS01820	COG0640	Transcriptional regulator
I6I24_RS01825	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
I6I24_RS01850	COG4575	ribosome binding
I6I24_RS01860	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
I6I24_RS01900	COG2814	Major facilitator Superfamily
I6I24_RS01905	COG1846	Transcriptional regulator
I6I24_RS01910	COG1566	PFAM secretion protein HlyD family protein
I6I24_RS01915	COG2814	Major facilitator Superfamily
I6I24_RS01935	COG1238	metal cluster binding
I6I24_RS01940	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
I6I24_RS01970	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
I6I24_RS01990	COG1546	Belongs to the CinA family
I6I24_RS01995	COG2951	lytic endotransglycosylase activity
I6I24_RS02000	COG3730	PTS system glucitol sorbitol-specific
I6I24_RS02005	COG3732	PTS system glucitol sorbitol-specific
I6I24_RS02015	COG1028	Short-chain dehydrogenase reductase Sdr
I6I24_RS02020	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
I6I24_RS02025	COG1349	DNA-binding transcription factor activity
I6I24_RS02050	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
I6I24_RS02055	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
I6I24_RS02065	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
I6I24_RS02075	COG3260	NADH ubiquinone oxidoreductase 20
I6I24_RS02080	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
I6I24_RS02085	COG3261	NADH dehydrogenase
I6I24_RS02085	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
I6I24_RS02090	COG0650	Formate hydrogenlyase subunit 4
I6I24_RS02095	COG0651	ATP synthesis coupled electron transport
I6I24_RS02100	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
I6I24_RS02115	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
I6I24_RS02120	COG0298	carbon dioxide binding
I6I24_RS02125	COG0409	Hydrogenase expression formation protein
I6I24_RS02130	COG0309	Hydrogenase expression formation protein (HypE)
I6I24_RS02150	COG1121	(ABC) transporter
I6I24_RS02155	COG1108	ABC-type Mn2 Zn2 transport systems permease components
I6I24_RS02160	COG1108	ABC-type Mn2 Zn2 transport systems permease components
I6I24_RS02335	COG2207	Transcriptional regulator
I6I24_RS02400	COG0477	Major facilitator Superfamily
I6I24_RS02410	COG2610	gluconate transmembrane transporter activity
I6I24_RS02415	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
I6I24_RS02420	COG3622	Belongs to the hyi family
I6I24_RS02425	COG0235	Class ii aldolase
I6I24_RS02435	COG2084	Dehydrogenase
I6I24_RS02440	COG1349	DNA-binding transcription factor activity
I6I24_RS02450	COG0163	prenyltransferase activity
I6I24_RS02455	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
I6I24_RS02525	COG2234	aminopeptidase activity
I6I24_RS02530	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
I6I24_RS02535	COG1518	maintenance of DNA repeat elements
I6I24_RS02550	COG1857	crispr-associated protein
I6I24_RS02565	COG1203	CRISPR-associated helicase, Cas3
I6I24_RS02590	COG0720	synthase
I6I24_RS02595	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
I6I24_RS02595	COG0321	lipoyl(octanoyl) transferase activity
I6I24_RS02600	COG0602	queuosine metabolic process
I6I24_RS02615	COG3956	TIGRFAM MazG family protein
I6I24_RS02625	COG3609	addiction module antidote protein, CC2985 family
I6I24_RS02630	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
I6I24_RS02640	COG3437	response regulator, receiver
I6I24_RS02640	COG2205	protein histidine kinase activity
I6I24_RS02640	COG3850	Histidine kinase
I6I24_RS02640	COG4999	Histidine kinase
I6I24_RS02645	COG1929	Belongs to the glycerate kinase type-1 family
I6I24_RS02650	COG4948	Mandelate Racemase Muconate Lactonizing
I6I24_RS02655	COG4948	Mandelate Racemase Muconate Lactonizing
I6I24_RS02660	COG2271	Major facilitator Superfamily
I6I24_RS02670	COG0716	FMN binding
I6I24_RS02680	COG3098	single-species biofilm formation
I6I24_RS02695	COG1611	Belongs to the LOG family
I6I24_RS02700	COG0814	amino acid
I6I24_RS02705	COG1760	l-serine dehydratase
I6I24_RS02715	COG1454	alcohol dehydrogenase
I6I24_RS02720	COG0235	Class ii aldolase
I6I24_RS02725	COG0738	Major facilitator superfamily
I6I24_RS02745	COG1349	DNA-binding transcription factor activity
I6I24_RS02755	COG2363	Small membrane protein
I6I24_RS02760	COG0583	DNA-binding transcription factor activity
I6I24_RS02770	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
I6I24_RS02775	COG2166	iron-sulfur cluster assembly
I6I24_RS02780	COG2962	Rard protein
I6I24_RS02785	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
I6I24_RS02790	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
I6I24_RS02805	COG0860	N-Acetylmuramoyl-L-alanine amidase
I6I24_RS02815	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
I6I24_RS02820	COG1074	ATP-dependent DNA helicase activity
I6I24_RS02830	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
I6I24_RS02835	COG4967	type IV pilus modification protein PilV
I6I24_RS02845	COG4795	General secretion pathway protein
I6I24_RS02850	COG2165	general secretion pathway protein
I6I24_RS02880	COG0861	Integral membrane protein TerC family
I6I24_RS02890	COG0667	Aldo Keto reductase
I6I24_RS02910	COG1609	Transcriptional regulator
I6I24_RS02920	COG0583	DNA-binding transcription factor activity
I6I24_RS02925	COG1794	racemase activity, acting on amino acids and derivatives
I6I24_RS02930	COG2814	Major facilitator Superfamily
I6I24_RS02935	COG1028	Short-chain dehydrogenase reductase Sdr
I6I24_RS02945	COG0183	Belongs to the thiolase family
I6I24_RS02960	COG0814	amino acid
I6I24_RS02995	COG3188	usher protein
I6I24_RS03040	COG4942	peptidase
I6I24_RS03095	COG1272	protein, Hemolysin III
I6I24_RS03105	COG2723	6-phospho-beta-galactosidase activity
I6I24_RS03130	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
I6I24_RS03135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
I6I24_RS03140	COG0006	proline dipeptidase activity
I6I24_RS03160	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
I6I24_RS03165	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
I6I24_RS03180	COG2968	Membrane
I6I24_RS03190	COG0668	transmembrane transport
I6I24_RS03195	COG0191	fructose-bisphosphate aldolase activity
I6I24_RS03225	COG1122	ATPase activity
I6I24_RS03230	COG1122	ATPase activity
I6I24_RS03235	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
I6I24_RS03240	COG0501	Belongs to the peptidase M48B family
I6I24_RS03250	COG2267	carboxylic ester hydrolase activity
I6I24_RS03255	COG2731	YhcH YjgK YiaL family protein
I6I24_RS03260	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
I6I24_RS03265	COG1063	alcohol dehydrogenase
I6I24_RS03270	COG0246	Mannitol dehydrogenase
I6I24_RS03280	COG2186	Transcriptional regulator
I6I24_RS03290	COG1166	arginine decarboxylase activity
I6I24_RS03315	COG2814	Major facilitator Superfamily
I6I24_RS03325	COG2356	endonuclease I
I6I24_RS03330	COG1385	rRNA (uridine-N3-)-methyltransferase activity
I6I24_RS03355	COG2805	Type II/IV secretion system protein
I6I24_RS03360	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
I6I24_RS03365	COG0762	integral membrane protein
I6I24_RS03380	COG0635	Involved in the biosynthesis of porphyrin-containing compound
I6I24_RS03390	COG0252	asparaginase activity
I6I24_RS03400	COG3171	Protein conserved in bacteria
I6I24_RS03425	COG2211	Major facilitator Superfamily
I6I24_RS03430	COG1982	Orn Lys Arg decarboxylase major
I6I24_RS03435	COG1811	Na channel or pump
I6I24_RS03450	COG0427	acetyl-CoA hydrolase
I6I24_RS03455	COG2030	dehydratase
I6I24_RS03460	COG2301	Belongs to the HpcH HpaI aldolase family
I6I24_RS03490	COG0531	amino acid
I6I24_RS03500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
I6I24_RS03505	COG1012	belongs to the aldehyde dehydrogenase family
I6I24_RS03530	COG2271	Major facilitator Superfamily
I6I24_RS03540	COG0246	Mannitol dehydrogenase
I6I24_RS03555	COG0754	glutathionylspermidine amidase activity
I6I24_RS03560	COG0625	glutathione transferase activity
I6I24_RS03570	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
I6I24_RS03575	COG0298	carbon dioxide binding
I6I24_RS03585	COG1773	rubredoxin
I6I24_RS03590	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
I6I24_RS03595	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
I6I24_RS03600	COG5557	Pfam Polysulphide reductase, NrfD
I6I24_RS03605	COG0437	4 iron, 4 sulfur cluster binding
I6I24_RS03610	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
I6I24_RS03620	COG0840	transmembrane signaling receptor activity
I6I24_RS03645	COG1028	Short-chain dehydrogenase reductase Sdr
I6I24_RS03650	COG0848	biopolymer transport protein
I6I24_RS03670	COG2207	Transcriptional regulator
I6I24_RS03675	COG1979	alcohol dehydrogenase
I6I24_RS03685	COG0471	metal ion transport
I6I24_RS03735	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
I6I24_RS03740	COG3111	PFAM Bacterial OB fold (BOF) protein
I6I24_RS03755	COG2249	NAD(P)H dehydrogenase (quinone) activity
I6I24_RS03760	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
I6I24_RS03770	COG3150	esterase
I6I24_RS03775	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
I6I24_RS03780	COG3151	Protein conserved in bacteria
I6I24_RS03785	COG0494	nUDIX hydrolase
I6I24_RS03800	COG0754	glutathionylspermidine amidase activity
I6I24_RS03805	COG3384	dioxygenase
I6I24_RS03845	COG1585	Membrane protein implicated in regulation of membrane protease activity
I6I24_RS03850	COG2268	Band 7 protein
I6I24_RS03870	COG3025	triphosphatase activity
I6I24_RS03875	COG4991	sh3 domain protein
I6I24_RS03890	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
I6I24_RS03915	COG0828	Belongs to the bacterial ribosomal protein bS21 family
I6I24_RS03940	COG2375	cellular response to nickel ion
I6I24_RS03945	COG1695	Transcriptional regulator
I6I24_RS03950	COG0840	transmembrane signaling receptor activity
I6I24_RS03955	COG0840	transmembrane signaling receptor activity
I6I24_RS03965	COG1902	pentaerythritol trinitrate reductase activity
I6I24_RS03965	COG0446	pyridine nucleotide-disulphide oxidoreductase
I6I24_RS03975	COG1451	nucleotide metabolic process
I6I24_RS03980	COG2949	membrane
I6I24_RS03985	COG0673	inositol 2-dehydrogenase activity
I6I24_RS04000	COG0586	Pfam SNARE associated Golgi protein
I6I24_RS04010	COG1422	Protein of unknown function (DUF1090)
I6I24_RS04015	COG4575	ribosome binding
I6I24_RS04020	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
I6I24_RS04030	COG2259	Doxx family
I6I24_RS04035	COG0435	Glutathione S-transferase
I6I24_RS04040	COG3152	Membrane
I6I24_RS04045	COG0583	DNA-binding transcription factor activity
I6I24_RS04050	COG1741	Belongs to the pirin family
I6I24_RS04065	COG0814	amino acid
I6I24_RS04070	COG1760	l-serine dehydratase
I6I24_RS04075	COG1882	Formate acetyltransferase
I6I24_RS04095	COG0583	DNA-binding transcription factor activity
I6I24_RS04105	COG1929	Belongs to the glycerate kinase type-1 family
I6I24_RS04110	COG2084	Dehydrogenase
I6I24_RS04120	COG2721	sulfolactate sulfo-lyase activity
I6I24_RS04125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
I6I24_RS04130	COG1349	DNA-binding transcription factor activity
I6I24_RS04140	COG1105	Belongs to the carbohydrate kinase PfkB family
I6I24_RS04145	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I6I24_RS04145	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I6I24_RS04145	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
I6I24_RS04160	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
I6I24_RS04165	COG3414	Phosphotransferase system galactitol-specific IIB component
I6I24_RS04170	COG3775	system Galactitol-specific IIC component
I6I24_RS04175	COG1063	alcohol dehydrogenase
I6I24_RS04185	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
I6I24_RS04205	COG2823	Periplasmic or secreted lipoprotein
I6I24_RS04210	COG0702	epimerase
I6I24_RS04215	COG0693	protein deglycase activity
I6I24_RS04230	COG3153	acetyltransferase
I6I24_RS04235	COG3154	lipid carrier protein
I6I24_RS04240	COG0826	peptidase U32
I6I24_RS04245	COG0826	peptidase U32
I6I24_RS04250	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
I6I24_RS04255	COG3034	peptidoglycan biosynthetic process
I6I24_RS04265	COG0814	amino acid
I6I24_RS04270	COG0513	Belongs to the DEAD box helicase family
I6I24_RS04340	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
I6I24_RS04350	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
I6I24_RS04370	COG1534	Rna-binding protein
I6I24_RS04380	COG2027	D-alanyl-D-alanine carboxypeptidase
I6I24_RS04390	COG0697	spore germination
I6I24_RS04405	COG0142	geranyltranstransferase activity
I6I24_RS04410	COG3423	Transcriptional regulator
I6I24_RS04420	COG5007	Belongs to the BolA IbaG family
I6I24_RS04425	COG3113	response to antibiotic
I6I24_RS04430	COG2854	intermembrane phospholipid transfer
I6I24_RS04435	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
I6I24_RS04440	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
I6I24_RS04445	COG1127	ABC transporter
I6I24_RS04450	COG0530	calcium, potassium:sodium antiporter activity
I6I24_RS04465	COG3117	lipopolysaccharide transmembrane transporter activity
I6I24_RS04470	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
I6I24_RS04475	COG1137	ATPase activity
I6I24_RS04500	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
I6I24_RS04505	COG0515	serine threonine protein kinase
I6I24_RS04515	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
I6I24_RS04520	COG0784	Response regulator, receiver
I6I24_RS04520	COG5002	protein histidine kinase activity
I6I24_RS04520	COG2198	Histidine kinase
I6I24_RS04525	COG1242	4 iron, 4 sulfur cluster binding
I6I24_RS04530	COG0070	glutamate synthase
I6I24_RS04530	COG0069	glutamate synthase activity
I6I24_RS04530	COG0067	glutamate synthase
I6I24_RS04535	COG0493	'glutamate synthase
I6I24_RS04540	COG4804	nuclease activity
I6I24_RS04545	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
I6I24_RS04550	COG0402	S-adenosylhomocysteine deaminase activity
I6I24_RS04555	COG2731	YhcH YjgK YiaL family protein
I6I24_RS04585	COG2969	positive regulation of protein catabolic process
I6I24_RS04590	COG0625	glutathione transferase activity
I6I24_RS04610	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
I6I24_RS04615	COG3105	Protein conserved in bacteria
I6I24_RS04620	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
I6I24_RS04630	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
I6I24_RS04635	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
I6I24_RS04650	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
I6I24_RS04655	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
I6I24_RS04660	COG0471	metal ion transport
I6I24_RS04670	COG2188	Transcriptional regulator
I6I24_RS04695	COG2732	(Barnase) inhibitor
I6I24_RS04715	COG0583	DNA-binding transcription factor activity
I6I24_RS04720	COG0312	modulator of DNA gyrase
I6I24_RS04725	COG3164	Protein of unknown function
I6I24_RS04740	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
I6I24_RS04745	COG1792	Involved in formation and maintenance of cell shape
I6I24_RS04750	COG1077	Cell shape determining protein MreB Mrl
I6I24_RS04755	COG2200	EAL domain
I6I24_RS04755	COG2199	diguanylate cyclase activity
I6I24_RS04760	COG0604	alcohol dehydrogenase
I6I24_RS04775	COG0511	ligase activity, forming carbon-carbon bonds
I6I24_RS04780	COG0439	Biotin carboxylase
I6I24_RS04785	COG3924	membrane
I6I24_RS04790	COG4145	pantothenate transmembrane transporter activity
I6I24_RS04810	COG2189	Belongs to the N(4) N(6)-methyltransferase family
I6I24_RS04825	COG1309	transcriptional regulator
I6I24_RS04830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
I6I24_RS04835	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
I6I24_RS04880	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
I6I24_RS04900	COG0551	DNA topoisomerase type I activity
I6I24_RS04910	COG0758	DNA mediated transformation
I6I24_RS04940	COG3036	rescue of stalled ribosome
I6I24_RS04945	COG0789	Transcriptional regulator
I6I24_RS04985	COG0201	protein transport
I6I24_RS05065	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
I6I24_RS05090	COG0051	transcription antitermination factor activity, RNA binding
I6I24_RS05145	COG2964	Protein conserved in bacteria
I6I24_RS05150	COG0545	Peptidyl-prolyl cis-trans isomerase
I6I24_RS05160	COG1047	Peptidyl-prolyl cis-trans
I6I24_RS05165	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
I6I24_RS05180	COG0488	(ABC) transporter
I6I24_RS05195	COG0429	hydrolase of the alpha beta-hydrolase fold
I6I24_RS05205	COG3954	Phosphoribulokinase
I6I24_RS05210	COG1765	OsmC-like protein
I6I24_RS05220	COG1289	transmembrane transporter activity
I6I24_RS05255	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
I6I24_RS05300	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
I6I24_RS05305	COG0338	D12 class N6 adenine-specific DNA methyltransferase
I6I24_RS05310	COG3266	domain, Protein
I6I24_RS05325	COG4796	Type ii and iii secretion system protein
I6I24_RS05340	COG3166	PFAM Fimbrial assembly family protein
I6I24_RS05345	COG4972	Pilus assembly protein
I6I24_RS05350	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
I6I24_RS05355	COG0494	nUDIX hydrolase
I6I24_RS05365	COG1011	Hydrolase
I6I24_RS05370	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
I6I24_RS05380	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
I6I24_RS05405	COG2183	response to ionizing radiation
I6I24_RS05410	COG1918	ferrous iron import across plasma membrane
I6I24_RS05425	COG5464	transposase or invertase
I6I24_RS05445	COG2610	gluconate transmembrane transporter activity
I6I24_RS05450	COG1640	4-alpha-glucanotransferase
I6I24_RS05455	COG0058	SHG alpha-glucan phosphorylase activity
I6I24_RS05465	COG3041	Addiction module toxin RelE StbE family
I6I24_RS05470	COG3077	Addiction module antitoxin, RelB DinJ family
I6I24_RS05480	COG1690	Belongs to the RtcB family
I6I24_RS05490	COG4650	regulator
I6I24_RS05510	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
I6I24_RS05525	COG0371	Dehydrogenase
I6I24_RS05535	COG0129	dihydroxy-acid dehydratase activity
I6I24_RS05540	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
I6I24_RS05545	COG1414	Transcriptional regulator
I6I24_RS05550	COG0058	SHG alpha-glucan phosphorylase activity
I6I24_RS05580	COG2095	MarC family integral membrane protein
I6I24_RS05585	COG2610	gluconate transmembrane transporter activity
I6I24_RS05590	COG3265	gluconokinase activity
I6I24_RS05595	COG1609	Transcriptional regulator
I6I24_RS05600	COG1741	Belongs to the pirin family
I6I24_RS05605	COG0673	inositol 2-dehydrogenase activity
I6I24_RS05610	COG1247	-acetyltransferase
I6I24_RS05615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
I6I24_RS05630	COG1735	metal-dependent hydrolase with the TIM-barrel fold
I6I24_RS05635	COG0405	Gamma-glutamyltransferase
I6I24_RS05645	COG0584	glycerophosphoryl diester phosphodiesterase
I6I24_RS05725	COG2177	Part of the ABC transporter FtsEX involved in
I6I24_RS05730	COG2884	Cell division ATP-binding protein ftsE
I6I24_RS05735	COG0552	protein localization to endoplasmic reticulum
I6I24_RS05740	COG0742	ribosomal rna small subunit methyltransferase
I6I24_RS05745	COG3776	membrane
I6I24_RS05755	COG3714	YhhN family
I6I24_RS05775	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
I6I24_RS05790	COG0628	permease
I6I24_RS05805	COG0842	Transport permease protein
I6I24_RS05810	COG0842	Transport permease protein
I6I24_RS05810	COG1129	ABC transporter
I6I24_RS05815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
I6I24_RS05820	COG2081	HI0933 family
I6I24_RS05825	COG0306	phosphate transporter
I6I24_RS05855	COG0671	phosphoesterase, PA-phosphatase related
I6I24_RS05860	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
I6I24_RS05865	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
I6I24_RS05875	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
I6I24_RS05880	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
I6I24_RS05885	COG2222	sugar isomerase
I6I24_RS05890	COG2188	Transcriptional regulator
I6I24_RS05910	COG2197	response regulator
I6I24_RS05915	COG0583	DNA-binding transcription factor activity
I6I24_RS05920	COG1295	ribonuclease BN
I6I24_RS05925	COG0477	Major facilitator Superfamily
I6I24_RS05930	COG2982	Protein involved in outer membrane biogenesis
I6I24_RS05935	COG2200	EAL domain
I6I24_RS05940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
I6I24_RS05955	COG2199	diguanylate cyclase activity
I6I24_RS05955	COG2200	EAL domain
I6I24_RS06015	COG0814	amino acid
I6I24_RS06020	COG4608	Belongs to the ABC transporter superfamily
I6I24_RS06025	COG0444	Belongs to the ABC transporter superfamily
I6I24_RS06030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
I6I24_RS06035	COG0601	transmembrane transport
I6I24_RS06040	COG0747	negative chemotaxis
I6I24_RS06100	COG5571	outer membrane autotransporter
I6I24_RS06105	COG2818	Glycosylase
I6I24_RS06110	COG0456	acetyltransferase
I6I24_RS06115	COG0243	molybdopterin cofactor binding
I6I24_RS06120	COG2885	chlorophyll binding
I6I24_RS06135	COG2944	sequence-specific DNA binding
I6I24_RS06140	COG1278	Cold shock
I6I24_RS06165	COG2801	Transposase and inactivated derivatives
I6I24_RS06185	COG3274	enterobacterial common antigen metabolic process
I6I24_RS06190	COG4682	membrane
I6I24_RS06195	COG1070	Carbohydrate kinase
I6I24_RS06205	COG1609	Transcriptional regulator
I6I24_RS06205	COG2207	Transcriptional regulator
I6I24_RS06210	COG2992	FlgJ-related protein
I6I24_RS06215	COG0366	Alpha amylase catalytic
I6I24_RS06220	COG3977	Valine--pyruvate aminotransferase
I6I24_RS06225	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
I6I24_RS06230	COG1414	Transcriptional regulator
I6I24_RS06240	COG2731	YhcH YjgK YiaL family protein
I6I24_RS06250	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
I6I24_RS06255	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
I6I24_RS06260	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
I6I24_RS06265	COG1070	Carbohydrate kinase
I6I24_RS06270	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
I6I24_RS06275	COG3623	hexulose-6-phosphate isomerase
I6I24_RS06280	COG0235	Class ii aldolase
I6I24_RS06295	COG1012	belongs to the aldehyde dehydrogenase family
I6I24_RS06300	COG1940	carbohydrate kinase activity
I6I24_RS06305	COG3276	selenocysteine insertion sequence binding
I6I24_RS06315	COG0625	glutathione transferase activity
I6I24_RS06320	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
I6I24_RS06320	COG2213	PTS system mannitol-specific
I6I24_RS06330	COG3722	fumarate hydratase activity
I6I24_RS06360	COG2186	Transcriptional regulator
I6I24_RS06370	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
I6I24_RS06375	COG1609	Transcriptional regulator
I6I24_RS06405	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
I6I24_RS06410	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
I6I24_RS06420	COG4942	peptidase
I6I24_RS06425	COG2861	carbohydrate metabolic process
I6I24_RS06430	COG1216	Glycosyl transferase, family 2
I6I24_RS06505	COG0438	transferase activity, transferring glycosyl groups
I6I24_RS06510	COG0859	PFAM glycosyl transferase family 9
I6I24_RS06515	COG1519	Transferase
I6I24_RS06545	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
I6I24_RS06570	COG1561	YicC-like family, N-terminal region
I6I24_RS06575	COG0583	DNA-binding transcription factor activity
I6I24_RS06585	COG2860	membrane
I6I24_RS06605	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
I6I24_RS06610	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
I6I24_RS06615	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
I6I24_RS06625	COG0786	glutamate:sodium symporter activity
I6I24_RS06630	COG2233	PERMEase
I6I24_RS06635	COG2982	Protein involved in outer membrane biogenesis
I6I24_RS06640	COG1501	Belongs to the glycosyl hydrolase 31 family
I6I24_RS06645	COG2211	Major facilitator Superfamily
I6I24_RS06665	COG0419	ATPase involved in DNA repair
I6I24_RS06685	COG2771	luxR family
I6I24_RS06700	COG3710	Transcriptional regulator
I6I24_RS06710	COG1335	isochorismatase
I6I24_RS06740	COG5464	transposase or invertase
I6I24_RS06755	COG3716	PTS system mannose fructose sorbose family IID component
I6I24_RS06760	COG3715	PTS system
I6I24_RS06765	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I6I24_RS06765	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
I6I24_RS06785	COG2723	6-phospho-beta-galactosidase activity
I6I24_RS06820	COG3775	system Galactitol-specific IIC component
I6I24_RS06825	COG3414	Phosphotransferase system galactitol-specific IIB component
I6I24_RS06830	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
I6I24_RS06830	COG3711	transcriptional antiterminator
I6I24_RS06835	COG2188	Transcriptional regulator
I6I24_RS06870	COG0738	Major facilitator superfamily
I6I24_RS06880	COG1349	DNA-binding transcription factor activity
I6I24_RS06885	COG0440	acetolactate synthase activity
I6I24_RS06890	COG0028	Belongs to the TPP enzyme family
I6I24_RS06915	COG2814	Major facilitator Superfamily
I6I24_RS06925	COG0583	DNA-binding transcription factor activity
I6I24_RS06930	COG2610	gluconate transmembrane transporter activity
I6I24_RS06940	COG0641	radical SAM
I6I24_RS06950	COG2149	membrane
I6I24_RS06970	COG5645	(Lipo)protein
I6I24_RS06975	COG0823	Involved in the tonB-independent uptake of proteins
I6I24_RS06980	COG4235	cytochrome complex assembly
I6I24_RS06980	COG3088	subunit of a heme lyase
I6I24_RS07000	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
I6I24_RS07005	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
I6I24_RS07010	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
I6I24_RS07015	COG4133	protoheme IX ABC transporter activity
I6I24_RS07020	COG1858	cytochrome C peroxidase
I6I24_RS07035	COG3005	denitrification pathway
I6I24_RS07040	COG0745	RESPONSE REGULATOR receiver
I6I24_RS07045	COG1879	ABC-type sugar transport system periplasmic component
I6I24_RS07050	COG2198	Histidine kinase
I6I24_RS07050	COG0784	Response regulator, receiver
I6I24_RS07050	COG2205	protein histidine kinase activity
I6I24_RS07055	COG2271	Major facilitator Superfamily
I6I24_RS07065	COG0800	Aldolase
I6I24_RS07070	COG3734	2-keto-3-deoxy-galactonokinase
I6I24_RS07075	COG2186	Transcriptional regulator
I6I24_RS07080	COG0561	phosphatase activity
I6I24_RS07085	COG2271	Major facilitator Superfamily
I6I24_RS07090	COG4948	Mandelate Racemase Muconate Lactonizing
I6I24_RS07170	COG2091	lysine biosynthetic process via aminoadipic acid
I6I24_RS07175	COG0431	NADPH-dependent FMN reductase
I6I24_RS07180	COG2252	PERMEase
I6I24_RS07185	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
I6I24_RS07190	COG0704	Plays a role in the regulation of phosphate uptake
I6I24_RS07200	COG0581	inorganic phosphate transmembrane transporter activity
I6I24_RS07205	COG0573	inorganic phosphate transmembrane transporter activity
I6I24_RS07210	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
I6I24_RS07215	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
I6I24_RS07215	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I6I24_RS07215	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I6I24_RS07220	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
I6I24_RS07225	COG4533	DNA binding
I6I24_RS07285	COG3312	ion transport
I6I24_RS07300	COG0716	FMN binding
I6I24_RS07305	COG1522	sequence-specific DNA binding
I6I24_RS07340	COG1172	Belongs to the binding-protein-dependent transport system permease family
I6I24_RS07350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
I6I24_RS07355	COG1609	Transcriptional regulator
I6I24_RS07365	COG2186	Transcriptional regulator
I6I24_RS07430	COG3978	acetolactate synthase activity
I6I24_RS07495	COG3118	belongs to the thioredoxin family
I6I24_RS07530	COG1088	dTDP-glucose 4,6-dehydratase activity
I6I24_RS07535	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
I6I24_RS07535	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
I6I24_RS07540	COG0456	acetyltransferase
I6I24_RS07545	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
I6I24_RS07550	COG2244	polysaccharide biosynthetic process
I6I24_RS07595	COG3071	HemY protein
I6I24_RS07600	COG2959	enzyme of heme biosynthesis
I6I24_RS07670	COG1011	Hydrolase
I6I24_RS07725	COG2267	carboxylic ester hydrolase activity
I6I24_RS07730	COG0561	phosphatase activity
I6I24_RS07750	COG0641	radical SAM
I6I24_RS07795	COG0805	protein transport
I6I24_RS07840	COG1739	Uncharacterized protein family UPF0029
I6I24_RS07880	COG1763	Mo-molybdopterin cofactor biosynthetic process
I6I24_RS07890	COG3084	Protein conserved in bacteria
I6I24_RS07905	COG0204	Acyl-transferase
I6I24_RS07960	COG0561	phosphatase activity
I6I24_RS08005	COG1501	Belongs to the glycosyl hydrolase 31 family
I6I24_RS08010	COG2017	converts alpha-aldose to the beta-anomer
I6I24_RS08030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
I6I24_RS08035	COG1349	DNA-binding transcription factor activity
I6I24_RS08040	COG1011	Hydrolase
I6I24_RS08055	COG0456	acetyltransferase
I6I24_RS08060	COG5499	transcription regulator containing HTH domain
I6I24_RS08065	COG4680	protein conserved in bacteria
I6I24_RS08075	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
I6I24_RS08090	COG2864	formate dehydrogenase
I6I24_RS08095	COG0437	4 iron, 4 sulfur cluster binding
I6I24_RS08125	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
I6I24_RS08140	COG1454	alcohol dehydrogenase
I6I24_RS08185	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
I6I24_RS08200	COG2258	MOSC domain
I6I24_RS08210	COG2205	protein histidine kinase activity
I6I24_RS08215	COG0745	RESPONSE REGULATOR receiver
I6I24_RS08220	COG3678	ATP-independent chaperone mediated protein folding
I6I24_RS08245	COG2211	Major facilitator Superfamily
I6I24_RS08260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
I6I24_RS08280	COG1070	Carbohydrate kinase
I6I24_RS08335	COG3152	Membrane
I6I24_RS08345	COG1494	fructose-1,6-bisphosphatase
I6I24_RS08355	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
I6I24_RS08370	COG1575	Belongs to the MenA family. Type 1 subfamily
I6I24_RS08385	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
I6I24_RS08390	COG1609	Transcriptional regulator
I6I24_RS08395	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
I6I24_RS08420	COG0626	cystathionine gamma-synthase activity
I6I24_RS08425	COG0527	aspartate kinase activity
I6I24_RS08425	COG0460	homoserine dehydrogenase
I6I24_RS08445	COG0737	Belongs to the 5'-nucleotidase family
I6I24_RS08460	COG3738	Protein conserved in bacteria
I6I24_RS08465	COG0371	Dehydrogenase
I6I24_RS08475	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
I6I24_RS08475	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
I6I24_RS08475	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
I6I24_RS08480	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I6I24_RS08485	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I6I24_RS08490	COG1882	Formate acetyltransferase
I6I24_RS08495	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
I6I24_RS08500	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I6I24_RS08505	COG2207	Transcriptional regulator
I6I24_RS08540	COG0583	DNA-binding transcription factor activity
I6I24_RS08650	COG0250	Participates in transcription elongation, termination and antitermination
I6I24_RS08715	COG2104	thiamine diphosphate biosynthetic process
I6I24_RS08720	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
I6I24_RS08825	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
I6I24_RS08870	COG3122	Protein conserved in bacteria
I6I24_RS08910	COG5301	cellulose 1,4-beta-cellobiosidase activity
I6I24_RS08940	COG2246	polysaccharide biosynthetic process
I6I24_RS09020	COG0527	aspartate kinase activity
I6I24_RS09045	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
I6I24_RS09100	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
I6I24_RS09110	COG0534	Mate efflux family protein
I6I24_RS09125	COG0735	belongs to the Fur family
I6I24_RS09175	COG2315	Protein conserved in bacteria
I6I24_RS09235	COG4943	cyclic-guanylate-specific phosphodiesterase activity
I6I24_RS09255	COG2252	PERMEase
I6I24_RS09260	COG0025	NhaP-type Na H and K H
I6I24_RS09265	COG0583	DNA-binding transcription factor activity
I6I24_RS09270	COG1380	Effector of murein hydrolase LrgA
I6I24_RS09275	COG1346	cytolysis
I6I24_RS09285	COG3162	membrane
I6I24_RS09300	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
I6I24_RS09305	COG0437	4 iron, 4 sulfur cluster binding
I6I24_RS09310	COG3301	Polysulphide reductase, NrfD
I6I24_RS09315	COG1138	Cytochrome C-type biogenesis protein
I6I24_RS09320	COG4235	cytochrome complex assembly
I6I24_RS09325	COG1301	dicarboxylic acid transport
I6I24_RS09330	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
I6I24_RS09350	COG2764	glyoxalase bleomycin resistance protein dioxygenase
I6I24_RS09355	COG2824	Alkylphosphonate utilization operon protein PhnA
I6I24_RS09385	COG0531	amino acid
I6I24_RS09390	COG2207	Transcriptional regulator
I6I24_RS09395	COG1982	Orn Lys Arg decarboxylase major
I6I24_RS09400	COG2169	Transcriptional regulator
I6I24_RS09415	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
I6I24_RS09415	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
I6I24_RS09420	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
I6I24_RS09430	COG4565	transcriptional regulatory protein
I6I24_RS09435	COG3290	protein histidine kinase activity
I6I24_RS09440	COG0243	molybdopterin cofactor binding
I6I24_RS09445	COG0437	4 iron, 4 sulfur cluster binding
I6I24_RS09450	COG3302	dmso reductase anchor subunit
I6I24_RS09455	COG3381	protein complex oligomerization
I6I24_RS09480	COG2197	response regulator
I6I24_RS09515	COG0789	Transcriptional regulator
I6I24_RS09530	COG1309	transcriptional regulator
I6I24_RS09545	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
I6I24_RS09550	COG1027	Aspartate ammonia-lyase
I6I24_RS09555	COG3030	protein affecting phage T7 exclusion by the F plasmid
I6I24_RS09560	COG0531	amino acid
I6I24_RS09600	COG5510	response to toxic substance
I6I24_RS09630	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
I6I24_RS09635	COG1053	succinate dehydrogenase
I6I24_RS09655	COG3264	Mechanosensitive ion channel
I6I24_RS09655	COG1511	domain protein
I6I24_RS09675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I6I24_RS09700	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
I6I24_RS09700	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
I6I24_RS09705	COG0802	atpase or kinase
I6I24_RS09730	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
I6I24_RS09735	COG0330	HflC and HflK could
I6I24_RS09740	COG0330	HflC and HflK could
I6I24_RS09745	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
I6I24_RS09760	COG0557	exoribonuclease II activity
I6I24_RS09770	COG3789	protein conserved in bacteria
I6I24_RS09790	COG3766	membrane
I6I24_RS09795	COG5463	Belongs to the UPF0441 family
I6I24_RS09800	COG0754	glutathionylspermidine amidase activity
I6I24_RS09805	COG1960	acyl-CoA dehydrogenase activity
I6I24_RS09815	COG3650	response to hydrogen peroxide
I6I24_RS09820	COG1073	alpha beta
I6I24_RS09885	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
I6I24_RS09900	COG3061	Opacity-associated protein A
I6I24_RS09905	COG0545	Peptidyl-prolyl cis-trans isomerase
I6I24_RS09910	COG1113	amino acid transport
I6I24_RS09920	COG0697	spore germination
I6I24_RS09925	COG0702	epimerase
I6I24_RS09930	COG1733	regulation of RNA biosynthetic process
I6I24_RS09945	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
I6I24_RS09955	COG1253	flavin adenine dinucleotide binding
I6I24_RS09975	COG2105	PFAM AIG2 family protein
I6I24_RS09980	COG2271	Major facilitator Superfamily
I6I24_RS09985	COG3964	amidohydrolase
I6I24_RS10000	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
I6I24_RS10005	COG1737	Transcriptional regulator
I6I24_RS10005	COG0837	glucose binding
I6I24_RS10010	COG0477	Major facilitator Superfamily
I6I24_RS10010	COG2814	Major facilitator Superfamily
I6I24_RS10015	COG0477	Major facilitator Superfamily
I6I24_RS10015	COG2814	Major facilitator Superfamily
I6I24_RS10020	COG3718	enzyme involved in inositol metabolism
I6I24_RS10050	COG5520	Belongs to the glycosyl hydrolase 30 family
I6I24_RS10055	COG1082	Xylose isomerase domain protein TIM barrel
I6I24_RS10065	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
I6I24_RS10070	COG3962	Belongs to the TPP enzyme family
I6I24_RS10075	COG0673	inositol 2-dehydrogenase activity
I6I24_RS10080	COG2814	Major facilitator Superfamily
I6I24_RS10090	COG1082	Xylose isomerase domain protein TIM barrel
I6I24_RS10100	COG0312	modulator of DNA gyrase
I6I24_RS10135	COG3964	amidohydrolase
I6I24_RS10150	COG3711	transcriptional antiterminator
I6I24_RS10150	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
I6I24_RS10155	COG3077	Addiction module antitoxin, RelB DinJ family
I6I24_RS10160	COG2026	Addiction module toxin, RelE StbE family
I6I24_RS10175	COG0366	Alpha amylase catalytic
I6I24_RS10230	COG1438	arginine binding
I6I24_RS10235	COG1288	antiporter activity
I6I24_RS10255	COG2731	YhcH YjgK YiaL family protein
I6I24_RS10295	COG2927	DNA polymerase III (CHI subunit)
I6I24_RS10305	COG0795	lipopolysaccharide-transporting ATPase activity
I6I24_RS10310	COG0795	lipopolysaccharide-transporting ATPase activity
I6I24_RS10315	COG1609	Transcriptional regulator
I6I24_RS10320	COG2610	gluconate transmembrane transporter activity
I6I24_RS10325	COG1028	Short-chain dehydrogenase reductase Sdr
I6I24_RS10330	COG1063	alcohol dehydrogenase
I6I24_RS10335	COG3265	gluconokinase activity
I6I24_RS10340	COG1064	alcohol dehydrogenase
I6I24_RS10350	COG0582	viral genome integration into host DNA
I6I24_RS10355	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
I6I24_RS10355	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
I6I24_RS10380	COG4133	protoheme IX ABC transporter activity
I6I24_RS10415	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
I6I24_RS10445	COG0412	Dienelactone hydrolase
I6I24_RS10450	COG2186	Transcriptional regulator
I6I24_RS10470	COG0583	DNA-binding transcription factor activity
I6I24_RS10475	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
I6I24_RS10480	COG0700	Nucleoside recognition
I6I24_RS10485	COG3366	ferrous iron transmembrane transporter activity
I6I24_RS10490	COG0477	Major facilitator Superfamily
I6I24_RS10495	COG2733	membrane
I6I24_RS10505	COG5464	transposase or invertase
I6I24_RS10510	COG1012	belongs to the aldehyde dehydrogenase family
I6I24_RS10545	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
I6I24_RS10550	COG1715	Restriction endonuclease
I6I24_RS10565	COG0523	cobalamin synthesis protein
I6I24_RS10570	COG2879	small protein
I6I24_RS10575	COG1966	Carbon starvation protein
I6I24_RS10580	COG0840	transmembrane signaling receptor activity
I6I24_RS10595	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I6I24_RS10600	COG3715	PTS system
I6I24_RS10605	COG3716	PTS system mannose fructose sorbose family IID component
I6I24_RS10610	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
I6I24_RS10630	COG1484	DNA-dependent DNA replication
I6I24_RS10645	COG2966	Psort location CytoplasmicMembrane, score
I6I24_RS10650	COG2197	response regulator
I6I24_RS10655	COG2197	response regulator
I6I24_RS10660	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
I6I24_RS10665	COG4114	ferric iron reductase
I6I24_RS10670	COG3706	GGDEF domain
I6I24_RS10700	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
I6I24_RS10710	COG1011	Hydrolase
I6I24_RS10720	COG2823	Periplasmic or secreted lipoprotein
I6I24_RS10730	COG4667	esterase of the alpha-beta hydrolase superfamily
I6I24_RS10735	COG0084	hydrolase, TatD family'
I6I24_RS10740	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
I6I24_RS10745	COG1328	CTP reductase activity
I6I24_RS10775	COG3188	usher protein
I6I24_RS10780	COG3121	Chaperone
I6I24_RS10785	COG3539	Fimbrial protein
I6I24_RS10800	COG3726	membrane protein affecting hemolysin expression
I6I24_RS10805	COG0560	Phosphoserine phosphatase
I6I24_RS10820	COG0488	(ABC) transporter
I6I24_RS10845	COG3708	Transcriptional regulator
I6I24_RS10845	COG2207	Transcriptional regulator
I6I24_RS10850	COG3045	CreA protein
I6I24_RS10855	COG0745	RESPONSE REGULATOR receiver
I6I24_RS10860	COG2205	protein histidine kinase activity
I6I24_RS10865	COG4452	Inner membrane protein CreD
I6I24_RS10885	COG3121	Chaperone
I6I24_RS10905	COG0745	RESPONSE REGULATOR receiver
I6I24_RS10915	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
I6I24_RS10925	COG0460	homoserine dehydrogenase
I6I24_RS10925	COG0527	aspartate kinase activity
I6I24_RS10935	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
I6I24_RS10945	COG1115	amino acid carrier protein
I6I24_RS10955	COG0521	Mo-molybdopterin cofactor biosynthetic process
I6I24_RS10960	COG1584	GPR1 FUN34 yaaH family protein
I6I24_RS10965	COG4735	regulation of single-species biofilm formation
I6I24_RS11030	COG3188	usher protein
I6I24_RS11045	COG3539	Fimbrial protein
I6I24_RS11050	COG3121	Chaperone
I6I24_RS11070	COG0583	DNA-binding transcription factor activity
I6I24_RS11085	COG0737	Belongs to the 5'-nucleotidase family
I6I24_RS11095	COG3119	arylsulfatase activity
I6I24_RS11100	COG0641	radical SAM
I6I24_RS11120	COG0583	DNA-binding transcription factor activity
I6I24_RS11145	COG0196	riboflavin kinase activity
I6I24_RS11160	COG1047	Peptidyl-prolyl cis-trans
I6I24_RS11315	COG2271	Major facilitator Superfamily
I6I24_RS11335	COG3119	arylsulfatase activity
I6I24_RS11350	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
I6I24_RS11400	COG0417	DNA replication proofreading
I6I24_RS11440	COG0586	Pfam SNARE associated Golgi protein
I6I24_RS11530	COG0768	penicillin binding
I6I24_RS11540	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
I6I24_RS11555	COG0772	Belongs to the SEDS family
I6I24_RS11580	COG0849	cell division
I6I24_RS11585	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
I6I24_RS11605	COG0494	nUDIX hydrolase
I6I24_RS11635	COG1459	type II secretion system
I6I24_RS11640	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
I6I24_RS11645	COG4969	Belongs to the N-Me-Phe pilin family
I6I24_RS11660	COG3725	Membrane protein required for beta-lactamase induction
I6I24_RS11665	COG3940	Belongs to the glycosyl hydrolase 43 family
I6I24_RS11670	COG2211	Major facilitator Superfamily
I6I24_RS11685	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
I6I24_RS11690	COG0508	dehydrogenase complex catalyzes the overall conversion of
I6I24_RS11695	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
I6I24_RS11745	COG1349	DNA-binding transcription factor activity
I6I24_RS11770	COG4993	Dehydrogenase
I6I24_RS11780	COG0288	reversible hydration of carbon dioxide
I6I24_RS11785	COG1131	(ABC) transporter
I6I24_RS11790	COG0842	Transport permease protein
I6I24_RS11795	COG3539	Fimbrial protein
I6I24_RS11815	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
I6I24_RS11820	COG0726	polysaccharide deacetylase
I6I24_RS11840	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
I6I24_RS11865	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
I6I24_RS11870	COG1643	Atp-dependent helicase
I6I24_RS11875	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
I6I24_RS11880	COG4774	siderophore transport
I6I24_RS11885	COG1120	ATPase activity
I6I24_RS11890	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
I6I24_RS11905	COG3188	usher protein
I6I24_RS11910	COG3121	Chaperone
I6I24_RS11915	COG3539	Fimbrial protein
I6I24_RS11920	COG3539	Fimbrial protein
I6I24_RS11950	COG2860	membrane
I6I24_RS11975	COG3835	regulator
I6I24_RS11985	COG0477	Major facilitator Superfamily
I6I24_RS12035	COG0575	Belongs to the CDS family
I6I24_RS12095	COG1982	Orn Lys Arg decarboxylase major
I6I24_RS12100	COG0346	lactoylglutathione lyase activity
I6I24_RS12110	COG4568	rho-dependent transcription termination
I6I24_RS12125	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
I6I24_RS12130	COG3015	lipoprotein NlpE involved in copper resistance
I6I24_RS12140	COG1720	tRNA m6t6A37 methyltransferase activity
I6I24_RS12205	COG0583	DNA-binding transcription factor activity
I6I24_RS12210	COG2814	Major facilitator Superfamily
I6I24_RS12220	COG2226	methyltransferase
I6I24_RS12225	COG0741	lytic transglycosylase activity
I6I24_RS12225	COG1388	LysM domain
I6I24_RS12235	COG2226	methyltransferase
I6I24_RS12345	COG3047	cAMP biosynthetic process
I6I24_RS12345	COG2885	chlorophyll binding
I6I24_RS12390	COG3209	COG3209 Rhs family protein
I6I24_RS12490	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
I6I24_RS12505	COG0121	glutamine amidotransferase
I6I24_RS12510	COG3034	peptidoglycan biosynthetic process
I6I24_RS12525	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
I6I24_RS12530	COG2195	Cleaves the N-terminal amino acid of tripeptides
I6I24_RS12585	COG2814	Major facilitator Superfamily
I6I24_RS12600	COG0179	Fumarylacetoacetate (FAA) hydrolase
I6I24_RS12635	COG3188	usher protein
I6I24_RS12640	COG3121	Chaperone
I6I24_RS12645	COG3539	Fimbrial protein
I6I24_RS12660	COG2200	EAL domain
I6I24_RS12705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
I6I24_RS12715	COG0789	Transcriptional regulator
I6I24_RS12725	COG2814	Major facilitator Superfamily
I6I24_RS12745	COG1271	oxidase subunit
I6I24_RS12750	COG1294	oxidase, subunit
I6I24_RS12770	COG1280	lysine exporter protein (LysE YggA)
I6I24_RS12805	COG0113	porphobilinogen synthase activity
I6I24_RS12820	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
I6I24_RS12825	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
I6I24_RS12870	COG3706	GGDEF domain
I6I24_RS12875	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
I6I24_RS12895	COG4126	flavin adenine dinucleotide binding
I6I24_RS12910	COG1940	carbohydrate kinase activity
I6I24_RS12915	COG2814	Major facilitator Superfamily
I6I24_RS12920	COG0419	ATPase involved in DNA repair
I6I24_RS12925	COG0420	3'-5' exonuclease activity
I6I24_RS12935	COG5002	protein histidine kinase activity
I6I24_RS12950	COG0366	Alpha amylase catalytic
I6I24_RS12955	COG0450	alkyl hydroperoxide reductase
I6I24_RS12975	COG1862	Preprotein translocase
I6I24_RS12985	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
I6I24_RS13015	COG4238	major outer membrane lipoprotein
I6I24_RS13025	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
I6I24_RS13025	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
I6I24_RS13045	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
I6I24_RS13050	COG0667	Aldo Keto reductase
I6I24_RS13060	COG0142	geranyltranstransferase activity
I6I24_RS13095	COG2188	Transcriptional regulator
I6I24_RS13125	COG2814	Major facilitator Superfamily
I6I24_RS13145	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
I6I24_RS13150	COG1845	cytochrome c oxidase, subunit III
I6I24_RS13155	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
I6I24_RS13160	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
I6I24_RS13165	COG2223	nitrite transmembrane transporter activity
I6I24_RS13170	COG3056	Lipoprotein
I6I24_RS13175	COG0271	Belongs to the BolA IbaG family
I6I24_RS13195	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
I6I24_RS13205	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
I6I24_RS13210	COG1555	photosystem II stabilization
I6I24_RS13215	COG0824	Thioesterase
I6I24_RS13225	COG4533	DNA binding
I6I24_RS13240	COG1522	sequence-specific DNA binding
I6I24_RS13245	COG1132	(ABC) transporter
I6I24_RS13250	COG1132	(ABC) transporter
I6I24_RS13255	COG0347	Belongs to the P(II) protein family
I6I24_RS13260	COG0004	ammonium transporteR
I6I24_RS13265	COG1946	Acyl-CoA thioesterase
I6I24_RS13270	COG3126	Type III secretion system lipoprotein chaperone (YscW)
I6I24_RS13275	COG3695	enzyme binding
I6I24_RS13285	COG4943	cyclic-guanylate-specific phosphodiesterase activity
I6I24_RS13305	COG0110	maltose O-acetyltransferase activity
I6I24_RS13320	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
I6I24_RS13325	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
I6I24_RS13330	COG1309	transcriptional regulator
I6I24_RS13335	COG3264	Mechanosensitive ion channel
I6I24_RS13335	COG1196	nuclear chromosome segregation
I6I24_RS13340	COG5464	transposase or invertase
I6I24_RS13350	COG3923	Primosomal replication protein n
I6I24_RS13355	COG2832	Protein of unknown function (DUF454)
I6I24_RS13400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
I6I24_RS13405	COG4651	solute:proton antiporter activity
I6I24_RS13405	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
I6I24_RS13410	COG2223	nitrite transmembrane transporter activity
I6I24_RS13425	COG3735	TraB family
I6I24_RS13445	COG1585	Membrane protein implicated in regulation of membrane protease activity
I6I24_RS13450	COG0330	HflC and HflK could
I6I24_RS13455	COG4619	ABC transporter
I6I24_RS13460	COG0390	transport system, permease component
I6I24_RS13465	COG3118	belongs to the thioredoxin family
I6I24_RS13470	COG0300	oxidoreductase activity
I6I24_RS13475	COG2755	lipolytic protein G-D-S-L family
I6I24_RS13480	COG4181	ATPase activity
I6I24_RS13485	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
I6I24_RS13495	COG1464	Belongs to the NlpA lipoprotein family
I6I24_RS13530	COG3960	tartronate-semialdehyde synthase activity
I6I24_RS13535	COG3622	Belongs to the hyi family
I6I24_RS13540	COG2084	Dehydrogenase
I6I24_RS13550	COG1953	Uracil, thiamine, allantoin
I6I24_RS13560	COG2233	PERMEase
I6I24_RS13565	COG1929	Belongs to the glycerate kinase type-1 family
I6I24_RS13570	COG3257	ureidoglycine aminohydrolase activity
I6I24_RS13575	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
I6I24_RS13580	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
I6I24_RS13585	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
I6I24_RS13590	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
I6I24_RS13600	COG0549	Belongs to the carbamate kinase family
I6I24_RS13605	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
I6I24_RS13610	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
I6I24_RS13620	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
I6I24_RS13640	COG1988	membrane-bound metal-dependent
I6I24_RS13645	COG2501	S4 domain
I6I24_RS13725	COG0463	Glycosyl transferase, family 2
I6I24_RS13730	COG2246	polysaccharide biosynthetic process
I6I24_RS13750	COG2207	Transcriptional regulator
I6I24_RS13755	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
I6I24_RS13765	COG3059	membrane
I6I24_RS13775	COG1113	amino acid transport
I6I24_RS13780	COG0668	transmembrane transport
I6I24_RS13790	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
I6I24_RS13790	COG3933	PFAM sigma-54 factor interaction domain-containing protein
I6I24_RS13795	COG2222	sugar isomerase
I6I24_RS13805	COG3716	PTS system mannose fructose sorbose family IID component
I6I24_RS13830	COG2315	Protein conserved in bacteria
I6I24_RS13860	COG4771	TonB-dependent receptor
I6I24_RS13865	COG2382	esterase
I6I24_RS13870	COG3251	PFAM MbtH domain protein
I6I24_RS13875	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I6I24_RS13875	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
I6I24_RS13880	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
I6I24_RS13885	COG1120	ATPase activity
I6I24_RS13890	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I6I24_RS13895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I6I24_RS13905	COG4592	Periplasmic binding protein
I6I24_RS13910	COG1169	isochorismate synthase
I6I24_RS13915	COG1021	2,3-dihydroxybenzoate-AMP ligase
I6I24_RS13920	COG1535	isochorismatase
I6I24_RS13920	COG3433	isochorismatase activity
I6I24_RS13925	COG1028	Short-chain dehydrogenase reductase Sdr
I6I24_RS13935	COG1966	Carbon starvation protein
I6I24_RS13940	COG2879	small protein
I6I24_RS13945	COG0371	Dehydrogenase
I6I24_RS13950	COG0436	Aminotransferase
I6I24_RS13955	COG1475	DNA binding
I6I24_RS13960	COG3969	phosphoadenosine phosphosulfate
I6I24_RS13965	COG0583	DNA-binding transcription factor activity
I6I24_RS13970	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
I6I24_RS13990	COG0243	molybdopterin cofactor binding
I6I24_RS14010	COG1063	alcohol dehydrogenase
I6I24_RS14015	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
I6I24_RS14020	COG3719	Belongs to the RNase T2 family
I6I24_RS14025	COG0471	metal ion transport
I6I24_RS14040	COG3051	citrate lyase alpha subunit
I6I24_RS14045	COG2301	Belongs to the HpcH HpaI aldolase family
I6I24_RS14055	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
I6I24_RS14060	COG3290	protein histidine kinase activity
I6I24_RS14065	COG4565	transcriptional regulatory protein
I6I24_RS14070	COG3069	C4-dicarboxylate transmembrane transporter activity
I6I24_RS14090	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
I6I24_RS14105	COG0583	DNA-binding transcription factor activity
I6I24_RS14120	COG1686	Belongs to the peptidase S11 family
I6I24_RS14130	COG0772	Belongs to the SEDS family
I6I24_RS14135	COG0768	penicillin binding
I6I24_RS14145	COG0799	negative regulation of ribosome biogenesis
I6I24_RS14165	COG1466	dna polymerase III delta subunit
I6I24_RS14195	COG3829	transcription factor binding
I6I24_RS14195	COG3290	protein histidine kinase activity
I6I24_RS14200	COG2888	peptidyl-tyrosine sulfation
I6I24_RS14215	COG2214	Heat shock protein DnaJ domain protein
I6I24_RS14225	COG2214	Heat shock protein DnaJ domain protein
I6I24_RS14230	COG0443	Heat shock 70 kDa protein
I6I24_RS14245	COG1126	abc transporter atp-binding protein
I6I24_RS14250	COG0765	amino acid transport
I6I24_RS14255	COG0765	amino acid transport
I6I24_RS14280	COG1702	phosphate starvation-inducible protein PhoH
I6I24_RS14290	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
I6I24_RS14335	COG0367	asparagine synthase
I6I24_RS14340	COG0647	UMP catabolic process
I6I24_RS14345	COG1846	Transcriptional regulator
I6I24_RS14345	COG1940	carbohydrate kinase activity
I6I24_RS14350	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
I6I24_RS14390	COG1053	succinate dehydrogenase
I6I24_RS14395	COG0583	DNA-binding transcription factor activity
I6I24_RS14400	COG0735	belongs to the Fur family
I6I24_RS14420	COG0596	Alpha beta hydrolase
I6I24_RS14430	COG0033	Phosphoglucomutase
I6I24_RS14440	COG0531	amino acid
I6I24_RS14445	COG1982	Orn Lys Arg decarboxylase major
I6I24_RS14455	COG0745	RESPONSE REGULATOR receiver
I6I24_RS14460	COG2205	protein histidine kinase activity
I6I24_RS14505	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
I6I24_RS14510	COG1984	allophanate hydrolase subunit 2
I6I24_RS14525	COG0582	viral genome integration into host DNA
I6I24_RS14565	COG1216	Glycosyl transferase, family 2
I6I24_RS14590	COG3180	Ammonia monooxygenase
I6I24_RS14610	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
I6I24_RS14625	COG0567	Dehydrogenase, E1 component
I6I24_RS14630	COG0508	dehydrogenase complex catalyzes the overall conversion of
I6I24_RS14640	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
I6I24_RS14645	COG1271	oxidase subunit
I6I24_RS14650	COG1294	oxidase, subunit
I6I24_RS14655	COG4890	Cyd operon protein YbgT
I6I24_RS14660	COG3790	cyd operon protein YbgE
I6I24_RS14665	COG0824	Thioesterase
I6I24_RS14670	COG0811	peptide transport
I6I24_RS14675	COG0848	biopolymer transport protein
I6I24_RS14680	COG3064	Membrane
I6I24_RS14690	COG2885	chlorophyll binding
I6I24_RS14695	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
I6I24_RS14755	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
I6I24_RS14760	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
I6I24_RS14760	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
I6I24_RS14765	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
I6I24_RS14770	COG0583	DNA-binding transcription factor activity
I6I24_RS14775	COG0583	DNA-binding transcription factor activity
I6I24_RS14780	COG0471	metal ion transport
I6I24_RS14780	COG0490	domain, Protein
I6I24_RS14805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I6I24_RS14810	COG1120	ATPase activity
I6I24_RS14820	COG2017	converts alpha-aldose to the beta-anomer
I6I24_RS14845	COG1119	ATPase activity
I6I24_RS14850	COG3585	molybdate ion transport
I6I24_RS14850	COG2005	Transcriptional regulator
I6I24_RS14860	COG0725	ABC transporter, periplasmic molybdate-binding protein
I6I24_RS14865	COG4149	molybdate abc transporter
I6I24_RS14875	COG0561	phosphatase activity
I6I24_RS14885	COG4677	pectinesterase activity
I6I24_RS14915	COG1881	PFAM PEBP family protein
I6I24_RS14970	COG0521	Mo-molybdopterin cofactor biosynthetic process
I6I24_RS14980	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
I6I24_RS14990	COG0670	Belongs to the BI1 family
I6I24_RS15010	COG0392	lysyltransferase activity
I6I24_RS15020	COG3568	Endonuclease Exonuclease Phosphatase
I6I24_RS15030	COG0842	Transport permease protein
I6I24_RS15035	COG0842	Transport permease protein
I6I24_RS15040	COG1131	(ABC) transporter
I6I24_RS15050	COG1309	transcriptional regulator
I6I24_RS15055	COG0513	Belongs to the DEAD box helicase family
I6I24_RS15065	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
I6I24_RS15075	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
I6I24_RS15085	COG0668	transmembrane transport
I6I24_RS15090	COG1126	abc transporter atp-binding protein
I6I24_RS15095	COG0765	amino acid transport
I6I24_RS15100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I6I24_RS15115	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
I6I24_RS15120	COG2194	sulfuric ester hydrolase activity
I6I24_RS15135	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
I6I24_RS15140	COG1376	ErfK ybiS ycfS ynhG family protein
I6I24_RS15145	COG0488	(ABC) transporter
I6I24_RS15165	COG0561	phosphatase activity
I6I24_RS15170	COG1882	Formate acetyltransferase
I6I24_RS15175	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
I6I24_RS15225	COG2301	Belongs to the HpcH HpaI aldolase family
I6I24_RS15245	COG1960	acyl-CoA dehydrogenase activity
I6I24_RS15255	COG0583	DNA-binding transcription factor activity
I6I24_RS15260	COG2610	gluconate transmembrane transporter activity
I6I24_RS15275	COG0625	glutathione transferase activity
I6I24_RS15280	COG1686	Belongs to the peptidase S11 family
I6I24_RS15285	COG1349	DNA-binding transcription factor activity
I6I24_RS15290	COG0671	phosphoesterase, PA-phosphatase related
I6I24_RS15295	COG2814	Major facilitator Superfamily
I6I24_RS15300	COG0561	phosphatase activity
I6I24_RS15305	COG0738	Major facilitator superfamily
I6I24_RS15310	COG3226	Transcriptional regulator
I6I24_RS15350	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
I6I24_RS15355	COG3842	ATPase activity
I6I24_RS15360	COG1176	ABC-type spermidine putrescine transport system, permease component I
I6I24_RS15365	COG1177	transmembrane transport
I6I24_RS15395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I6I24_RS15400	COG4160	amino acid transport
I6I24_RS15405	COG4215	(ABC) transporter
I6I24_RS15410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I6I24_RS15415	COG1126	abc transporter atp-binding protein
I6I24_RS15430	COG3023	N-Acetylmuramoyl-L-alanine amidase
I6I24_RS15435	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
I6I24_RS15440	COG0702	epimerase
I6I24_RS15445	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
I6I24_RS15450	COG0028	Belongs to the TPP enzyme family
I6I24_RS15455	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
I6I24_RS15465	COG2431	L-lysine efflux transmembrane transporter activity
I6I24_RS15470	COG3593	DNA synthesis involved in DNA repair
I6I24_RS15475	COG2990	Protein conserved in bacteria
I6I24_RS15480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
I6I24_RS15490	COG1278	Cold shock
I6I24_RS15500	COG0542	response to heat
I6I24_RS15520	COG1335	isochorismatase
I6I24_RS15530	COG0583	DNA-binding transcription factor activity
I6I24_RS15550	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
I6I24_RS15555	COG4988	ABC transporter
I6I24_RS15560	COG0492	ferredoxin-NADP+ reductase activity
I6I24_RS15580	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
I6I24_RS15590	COG0243	molybdopterin cofactor binding
I6I24_RS15595	COG0437	4 iron, 4 sulfur cluster binding
I6I24_RS15600	COG3302	dmso reductase anchor subunit
I6I24_RS15610	COG0531	amino acid
I6I24_RS15615	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
I6I24_RS15630	COG1882	Formate acetyltransferase
I6I24_RS15635	COG2116	formate transmembrane transporter activity
I6I24_RS15640	COG1944	ATP diphosphatase activity
I6I24_RS15645	COG2323	membrane
I6I24_RS15660	COG0501	Belongs to the peptidase M48B family
I6I24_RS15670	COG0539	negative regulation of cytoplasmic translation
I6I24_RS15680	COG0658	competence protein
I6I24_RS15680	COG2333	competence protein COMEC
I6I24_RS15695	COG3214	Protein conserved in bacteria
I6I24_RS15710	COG3173	Aminoglycoside phosphotransferase
I6I24_RS15715	COG1434	Gram-negative-bacterium-type cell wall biogenesis
I6I24_RS15720	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
I6I24_RS15730	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
I6I24_RS15740	COG2989	Protein conserved in bacteria
I6I24_RS15745	COG3108	Peptidase M15
I6I24_RS15750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
I6I24_RS15770	COG1522	sequence-specific DNA binding
I6I24_RS15780	COG1115	amino acid carrier protein
I6I24_RS15790	COG0582	viral genome integration into host DNA
I6I24_RS15810	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
I6I24_RS15850	COG1484	DNA-dependent DNA replication
I6I24_RS15895	COG0484	heat shock protein binding
I6I24_RS16040	COG5301	cellulose 1,4-beta-cellobiosidase activity
I6I24_RS16070	COG2135	peptidase activity
I6I24_RS16090	COG0308	aminopeptidase N
I6I24_RS16105	COG0633	Ferredoxin
I6I24_RS16105	COG3217	Mosc domain protein beta barrel domain protein
I6I24_RS16115	COG0488	(ABC) transporter
I6I24_RS16120	COG2995	paraquat-inducible protein a
I6I24_RS16125	COG3008	intermembrane lipid transfer
I6I24_RS16125	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
I6I24_RS16130	COG3009	Protein conserved in bacteria
I6I24_RS16135	COG3130	regulation of translation
I6I24_RS16145	COG1067	ATP-dependent peptidase activity
I6I24_RS16165	COG3070	regulator of competence-specific genes
I6I24_RS16170	COG1289	transmembrane transporter activity
I6I24_RS16175	COG3304	Inner membrane component domain
I6I24_RS16180	COG0210	DNA helicase
I6I24_RS16195	COG1832	CoA-binding protein
I6I24_RS16210	COG1881	PFAM PEBP family protein
I6I24_RS16230	COG0670	Belongs to the BI1 family
I6I24_RS16280	COG2205	protein histidine kinase activity
I6I24_RS16285	COG0745	RESPONSE REGULATOR receiver
I6I24_RS16300	COG2368	4-hydroxyphenylacetate
I6I24_RS16305	COG1846	Transcriptional regulator
I6I24_RS16315	COG1012	belongs to the aldehyde dehydrogenase family
I6I24_RS16320	COG3384	dioxygenase
I6I24_RS16330	COG3971	2-oxopent-4-enoate hydratase activity
I6I24_RS16375	COG4232	protein-disulfide reductase activity
I6I24_RS16380	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
I6I24_RS16380	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
I6I24_RS16385	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
I6I24_RS16405	COG3729	General stress protein
I6I24_RS16410	COG1309	transcriptional regulator
I6I24_RS16430	COG1702	phosphate starvation-inducible protein PhoH
I6I24_RS16435	COG1737	Transcriptional regulator
I6I24_RS16440	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
I6I24_RS16460	COG2814	Major facilitator Superfamily
I6I24_RS16465	COG0673	inositol 2-dehydrogenase activity
I6I24_RS16495	COG3381	protein complex oligomerization
I6I24_RS16550	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
I6I24_RS16570	COG5645	(Lipo)protein
I6I24_RS16585	COG1560	Kdo2-lipid A biosynthetic process
I6I24_RS16600	COG3038	cytochrome b561
I6I24_RS16635	COG2999	glutathione oxidoreductase activity
I6I24_RS16645	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
I6I24_RS16735	COG1530	ribonuclease E activity
I6I24_RS16795	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
I6I24_RS16800	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
I6I24_RS16805	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
I6I24_RS16815	COG0470	DNA polymerase III
I6I24_RS16820	COG0084	hydrolase, TatD family'
I6I24_RS16830	COG4773	Receptor
I6I24_RS16835	COG0537	adenosine 5'-monophosphoramidase activity
I6I24_RS16840	COG5633	Lipoprotein
I6I24_RS16865	COG1252	NADH dehydrogenase
I6I24_RS16870	COG3134	Outer membrane lipoprotein
I6I24_RS16875	COG1309	transcriptional regulator
I6I24_RS16885	COG1376	ErfK ybiS ycfS ynhG family protein
I6I24_RS16885	COG1388	LysM domain
I6I24_RS16890	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
I6I24_RS16895	COG4591	ABC-type transport system involved in lipoprotein release permease component
I6I24_RS16900	COG1136	(ABC) transporter
I6I24_RS16905	COG4591	ABC-type transport system involved in lipoprotein release permease component
I6I24_RS16925	COG1177	transmembrane transport
I6I24_RS16960	COG2850	peptidyl-arginine hydroxylation
I6I24_RS16975	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
I6I24_RS17005	COG0538	isocitrate dehydrogenase activity
I6I24_RS17060	COG0071	Belongs to the small heat shock protein (HSP20) family
I6I24_RS17070	COG3038	cytochrome b561
I6I24_RS17100	COG1124	(ABC) transporter
I6I24_RS17105	COG0668	transmembrane transport
I6I24_RS17120	COG3443	Belongs to the bacterial solute-binding protein 9 family
I6I24_RS17135	COG0789	Transcriptional regulator
I6I24_RS17150	COG1605	Chorismate mutase
I6I24_RS17175	COG2261	transglycosylase associated protein
I6I24_RS17185	COG3042	response to heat
I6I24_RS17195	COG3189	MarR family transcriptional regulator
I6I24_RS17200	COG2807	transmembrane transport
I6I24_RS17205	COG2207	Transcriptional regulator
I6I24_RS17220	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
I6I24_RS17225	COG2199	diguanylate cyclase activity
I6I24_RS17240	COG2766	serine protein kinase
I6I24_RS17245	COG3713	MltA-interacting MipA family protein
I6I24_RS17250	COG0641	radical SAM
I6I24_RS17255	COG0656	L-ascorbic acid biosynthetic process
I6I24_RS17275	COG3139	Protein of unknown function (DUF1315)
I6I24_RS17280	COG1335	isochorismatase
I6I24_RS17285	COG0252	asparaginase activity
I6I24_RS17290	COG0616	signal peptide processing
I6I24_RS17295	COG0778	Nitroreductase
I6I24_RS17320	COG0494	nUDIX hydrolase
I6I24_RS17355	COG3678	ATP-independent chaperone mediated protein folding
I6I24_RS17370	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
I6I24_RS17375	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
I6I24_RS17380	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
I6I24_RS17385	COG1447	Phosphotransferase system cellobiose-specific component IIA
I6I24_RS17390	COG1917	Cupin 2, conserved barrel domain protein
I6I24_RS17390	COG2169	Transcriptional regulator
I6I24_RS17395	COG1486	melibiose metabolic process
I6I24_RS17405	COG0753	catalase activity
I6I24_RS17415	COG1823	symporter activity
I6I24_RS17420	COG1988	membrane-bound metal-dependent
I6I24_RS17425	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
I6I24_RS17435	COG3001	Fructosamine kinase
I6I24_RS17445	COG1105	Belongs to the carbohydrate kinase PfkB family
I6I24_RS17450	COG3137	Salt-induced outer membrane protein
I6I24_RS17525	COG0386	Belongs to the glutathione peroxidase family
I6I24_RS17535	COG0791	NLP P60 protein
I6I24_RS17550	COG4256	Hemin uptake protein
I6I24_RS17565	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
I6I24_RS17565	COG0574	Belongs to the PEP-utilizing enzyme family
I6I24_RS17570	COG0318	PFAM AMP-dependent synthetase and ligase
I6I24_RS17575	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
I6I24_RS17580	COG0644	oxidoreductase
I6I24_RS17585	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
I6I24_RS17590	COG2086	electron transfer activity
I6I24_RS17595	COG2207	Transcriptional regulator
I6I24_RS17595	COG1917	Cupin 2, conserved barrel domain protein
I6I24_RS17600	COG1960	acyl-CoA dehydrogenase activity
I6I24_RS17605	COG4670	ketone body catabolic process
I6I24_RS17625	COG0738	Major facilitator superfamily
I6I24_RS17640	COG0628	permease
I6I24_RS17645	COG0247	lactate metabolic process
I6I24_RS17645	COG0277	FAD linked oxidase domain protein
I6I24_RS17650	COG2050	protein possibly involved in aromatic compounds catabolism
I6I24_RS17660	COG1823	symporter activity
I6I24_RS17665	COG0316	Belongs to the HesB IscA family
I6I24_RS17670	COG0719	Fe-S assembly protein
I6I24_RS17675	COG0396	ATPase activity
I6I24_RS17680	COG0719	Fe-S assembly protein
I6I24_RS17695	COG1376	ErfK ybiS ycfS ynhG family protein
I6I24_RS17715	COG0531	amino acid
I6I24_RS17720	COG2267	carboxylic ester hydrolase activity
I6I24_RS17730	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
I6I24_RS17765	COG3272	Protein of unknown function (DUF1722)
I6I24_RS17770	COG0789	Transcriptional regulator
I6I24_RS17950	COG0307	riboflavin synthase, alpha
I6I24_RS17955	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
I6I24_RS17960	COG2814	Major facilitator Superfamily
I6I24_RS17965	COG0583	DNA-binding transcription factor activity
I6I24_RS17985	COG0791	NLP P60 protein
I6I24_RS17990	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
I6I24_RS18005	COG1902	pentaerythritol trinitrate reductase activity
I6I24_RS18010	COG1309	transcriptional regulator
I6I24_RS18015	COG3313	Fe-S protein
I6I24_RS18020	COG4989	oxidoreductase activity
I6I24_RS18035	COG1566	PFAM secretion protein HlyD family protein
I6I24_RS18060	COG3895	Periplasmic Protein
I6I24_RS18080	COG0625	glutathione transferase activity
I6I24_RS18090	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
I6I24_RS18140	COG0673	inositol 2-dehydrogenase activity
I6I24_RS18160	COG5339	Protein conserved in bacteria
I6I24_RS18185	COG2205	protein histidine kinase activity
I6I24_RS18190	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
I6I24_RS18195	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
I6I24_RS18200	COG0745	RESPONSE REGULATOR receiver
I6I24_RS18205	COG3136	membrane protein required for alginate biosynthesis
I6I24_RS18210	COG0531	amino acid
I6I24_RS18220	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
I6I24_RS18225	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
I6I24_RS18230	COG0628	permease
I6I24_RS18245	COG3591	Belongs to the peptidase S1B family
I6I24_RS18255	COG2814	Major facilitator Superfamily
I6I24_RS18260	COG0583	DNA-binding transcription factor activity
I6I24_RS18265	COG1940	carbohydrate kinase activity
I6I24_RS18305	COG3302	dmso reductase anchor subunit
I6I24_RS18310	COG0437	4 iron, 4 sulfur cluster binding
I6I24_RS18315	COG0243	molybdopterin cofactor binding
I6I24_RS18320	COG0243	molybdopterin cofactor binding
I6I24_RS18335	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
I6I24_RS18355	COG1063	alcohol dehydrogenase
I6I24_RS18365	COG0246	Mannitol dehydrogenase
I6I24_RS18375	COG1802	Transcriptional regulator
I6I24_RS18380	COG4221	oxidoreductase activity
I6I24_RS18390	COG3729	General stress protein
I6I24_RS18395	COG1546	Belongs to the CinA family
I6I24_RS18400	COG3111	PFAM Bacterial OB fold (BOF) protein
I6I24_RS18410	COG2814	Major facilitator Superfamily
I6I24_RS18445	COG0583	DNA-binding transcription factor activity
I6I24_RS18450	COG1012	belongs to the aldehyde dehydrogenase family
I6I24_RS18465	COG3781	membrane
I6I24_RS18490	COG1773	rubredoxin
I6I24_RS18515	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
I6I24_RS18520	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
I6I24_RS18530	COG2186	Transcriptional regulator
I6I24_RS18535	COG1063	alcohol dehydrogenase
I6I24_RS18540	COG2271	Major facilitator Superfamily
I6I24_RS18565	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
I6I24_RS18570	COG0251	oxidation-reduction process
I6I24_RS18610	COG1609	Transcriptional regulator
I6I24_RS18615	COG1757	Na H antiporter
I6I24_RS18620	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
I6I24_RS18635	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
I6I24_RS18650	COG1764	response to oxidative stress
I6I24_RS18670	COG1064	alcohol dehydrogenase
I6I24_RS18675	COG2864	formate dehydrogenase
I6I24_RS18680	COG0437	4 iron, 4 sulfur cluster binding
I6I24_RS18720	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
I6I24_RS18725	COG1140	nitrate reductase beta subunit
I6I24_RS18730	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
I6I24_RS18735	COG2181	nitrate reductase activity
I6I24_RS18770	COG4772	TonB-dependent receptor
I6I24_RS18775	COG1802	Transcriptional regulator
I6I24_RS18780	COG2130	NADP-dependent
I6I24_RS18790	COG3238	Protein conserved in bacteria
I6I24_RS18830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
I6I24_RS18835	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
I6I24_RS18860	COG0826	peptidase U32
I6I24_RS18865	COG1396	sequence-specific DNA binding
I6I24_RS18870	COG3135	benzoate transporter
I6I24_RS18880	COG0500	methyltransferase
I6I24_RS18885	COG1275	C4-dicarboxylate transporter malic acid transport protein
I6I24_RS18890	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
I6I24_RS18895	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
I6I24_RS18905	COG3414	Phosphotransferase system galactitol-specific IIB component
I6I24_RS18910	COG3775	system Galactitol-specific IIC component
I6I24_RS18915	COG0434	BtpA family
I6I24_RS18920	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
I6I24_RS18925	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
I6I24_RS18930	COG1349	DNA-binding transcription factor activity
I6I24_RS18940	COG1304	FMN binding
I6I24_RS18945	COG2353	YceI-like domain
I6I24_RS18955	COG2272	Belongs to the type-B carboxylesterase lipase family
I6I24_RS18960	COG5383	Protein conserved in bacteria
I6I24_RS18965	COG0583	DNA-binding transcription factor activity
I6I24_RS18970	COG0840	transmembrane signaling receptor activity
I6I24_RS19005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I6I24_RS19010	COG0765	amino acid transport
I6I24_RS19020	COG0765	amino acid transport
I6I24_RS19030	COG0500	methyltransferase
I6I24_RS19035	COG3038	cytochrome b561
I6I24_RS19040	COG1434	Gram-negative-bacterium-type cell wall biogenesis
I6I24_RS19045	COG1643	Atp-dependent helicase
I6I24_RS19060	COG3784	Protein of unknown function (DUF1318)
I6I24_RS19070	COG2911	Protein conserved in bacteria
I6I24_RS19075	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
I6I24_RS19080	COG3187	Heat shock protein
I6I24_RS19085	COG3042	response to heat
I6I24_RS19095	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
I6I24_RS19095	COG0674	pyruvate-flavodoxin oxidoreductase activity
I6I24_RS19095	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
I6I24_RS19095	COG1013	pyruvate-flavodoxin oxidoreductase activity
I6I24_RS19105	COG2076	Multidrug Resistance protein
I6I24_RS19120	COG0513	Belongs to the DEAD box helicase family
I6I24_RS19130	COG0840	transmembrane signaling receptor activity
I6I24_RS19135	COG2840	Smr protein MutS2
I6I24_RS19155	COG3182	Iron-regulated membrane protein
I6I24_RS19160	COG0668	transmembrane transport
I6I24_RS19180	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
I6I24_RS19215	COG1309	transcriptional regulator
I6I24_RS19220	COG1028	Short-chain dehydrogenase reductase Sdr
I6I24_RS19225	COG0656	L-ascorbic acid biosynthetic process
I6I24_RS19230	COG0583	DNA-binding transcription factor activity
I6I24_RS19240	COG4166	transmembrane transport
I6I24_RS19245	COG2866	Carboxypeptidase
I6I24_RS19250	COG4948	Mandelate Racemase Muconate Lactonizing
I6I24_RS19270	COG3106	COG3106 Predicted ATPase
I6I24_RS19275	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
I6I24_RS19285	COG1983	PspC domain protein
I6I24_RS19295	COG1842	Phage shock protein A
I6I24_RS19300	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
I6I24_RS19355	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
I6I24_RS19355	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
I6I24_RS19365	COG5001	Diguanylate cyclase
I6I24_RS19375	COG1349	DNA-binding transcription factor activity
I6I24_RS19395	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
I6I24_RS19400	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
I6I24_RS19405	COG0671	phosphoesterase, PA-phosphatase related
I6I24_RS19445	COG0616	signal peptide processing
I6I24_RS19450	COG1028	Short-chain dehydrogenase reductase Sdr
I6I24_RS19465	COG0009	L-threonylcarbamoyladenylate synthase
I6I24_RS19505	COG3729	General stress protein
I6I24_RS19510	COG3685	Protein conserved in bacteria
I6I24_RS19515	COG3685	Protein conserved in bacteria
I6I24_RS19520	COG3546	catalase activity
I6I24_RS19530	COG0727	PFAM Uncharacterised protein family (UPF0153)
I6I24_RS19555	COG2350	Protein conserved in bacteria
I6I24_RS19575	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
I6I24_RS19605	COG2095	MarC family integral membrane protein
I6I24_RS19610	COG1454	alcohol dehydrogenase
I6I24_RS19610	COG1012	belongs to the aldehyde dehydrogenase family
I6I24_RS19625	COG1210	Utp--glucose-1-phosphate uridylyltransferase
I6I24_RS19630	COG0745	RESPONSE REGULATOR receiver
I6I24_RS19635	COG1752	Esterase of the alpha-beta hydrolase superfamily
I6I24_RS19645	COG0788	formyltetrahydrofolate deformylase activity
I6I24_RS19690	COG2181	nitrate reductase activity
I6I24_RS19695	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
I6I24_RS19700	COG1140	nitrate reductase beta subunit
I6I24_RS19705	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
I6I24_RS19710	COG2223	nitrite transmembrane transporter activity
I6I24_RS19715	COG3850	Histidine kinase
I6I24_RS19720	COG2197	response regulator
I6I24_RS19725	COG4932	domain protein
I6I24_RS19730	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
I6I24_RS19735	COG4572	Cation transport regulator
I6I24_RS19740	COG0387	Pfam Sodium calcium exchanger
I6I24_RS19790	COG0659	secondary active sulfate transmembrane transporter activity
I6I24_RS19805	COG0012	GTP binding
I6I24_RS19815	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
I6I24_RS19825	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
I6I24_RS19830	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
I6I24_RS19835	COG1999	signal sequence binding
I6I24_RS19840	COG1773	rubredoxin
I6I24_RS19845	COG1271	oxidase subunit
I6I24_RS19850	COG1294	oxidase, subunit
I6I24_RS19860	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
I6I24_RS19885	COG1619	proteins homologs of microcin C7 resistance protein MccF
I6I24_RS19905	COG2719	SpoVR family
I6I24_RS19945	COG0179	Fumarylacetoacetate (FAA) hydrolase
I6I24_RS19960	COG2894	cell division
I6I24_RS19970	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
I6I24_RS19985	COG3065	identical protein binding
I6I24_RS19995	COG1199	ATP-dependent helicase activity
I6I24_RS20000	COG0251	oxidation-reduction process
I6I24_RS20020	COG1760	l-serine dehydratase
I6I24_RS20025	COG2200	EAL domain
I6I24_RS20030	COG1253	flavin adenine dinucleotide binding
I6I24_RS20035	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
I6I24_RS20035	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I6I24_RS20040	COG3715	PTS system
I6I24_RS20045	COG3716	PTS system mannose fructose sorbose family IID component
I6I24_RS20060	COG2226	methyltransferase
I6I24_RS20065	COG0768	penicillin binding
I6I24_RS20095	COG1414	Transcriptional regulator
I6I24_RS20100	COG2814	Major facilitator Superfamily
I6I24_RS20120	COG1956	GAF domain-containing protein
I6I24_RS20125	COG2995	paraquat-inducible protein a
I6I24_RS20130	COG3008	intermembrane lipid transfer
I6I24_RS20165	COG5562	phage envelope protein
I6I24_RS20175	COG0454	-acetyltransferase
I6I24_RS20280	COG1276	copper resistance
I6I24_RS20285	COG2372	response to copper ion
I6I24_RS20295	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
I6I24_RS20300	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
I6I24_RS20305	COG1770	oligopeptidase
I6I24_RS20310	COG2979	Protein of unknown function (DUF533)
I6I24_RS20320	COG3141	response to X-ray
I6I24_RS20330	COG0800	Aldolase
I6I24_RS20335	COG0129	dihydroxy-acid dehydratase activity
I6I24_RS20340	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
I6I24_RS20345	COG1737	Transcriptional regulator
I6I24_RS20355	COG1560	Kdo2-lipid A biosynthetic process
I6I24_RS20360	COG0739	heme binding
I6I24_RS20365	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
I6I24_RS20375	COG1108	ABC-type Mn2 Zn2 transport systems permease components
I6I24_RS20410	COG0494	nUDIX hydrolase
I6I24_RS20420	COG1335	isochorismatase
I6I24_RS20425	COG1801	Protein of unknown function DUF72
I6I24_RS20430	COG3788	relative of glutathione S-transferase, MAPEG superfamily
I6I24_RS20450	COG3102	Protein conserved in bacteria
I6I24_RS20465	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
I6I24_RS20570	COG1528	Iron-storage protein
I6I24_RS20585	COG1528	Iron-storage protein
I6I24_RS20595	COG0814	amino acid
I6I24_RS20600	COG3012	SEC-C Motif Domain Protein
I6I24_RS20600	COG3318	Belongs to the UPF0149 family
I6I24_RS20645	COG2197	response regulator
I6I24_RS20660	COG2197	response regulator
I6I24_RS20665	COG1126	abc transporter atp-binding protein
I6I24_RS20670	COG0765	amino acid transport
I6I24_RS20680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I6I24_RS20740	COG0425	Belongs to the sulfur carrier protein TusA family
I6I24_RS20845	COG5475	Uncharacterized small protein (DUF2158)
I6I24_RS20850	COG2354	Protein conserved in bacteria
I6I24_RS20855	COG0697	spore germination
I6I24_RS20860	COG3727	T/G mismatch-specific endonuclease activity
I6I24_RS20865	COG0270	DNA (cytosine-5-)-methyltransferase activity
I6I24_RS20870	COG1418	mRNA catabolic process
I6I24_RS20880	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
I6I24_RS20910	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
I6I24_RS20930	COG3778	Protein conserved in bacteria
I6I24_RS20935	COG3299	homolog of phage Mu protein gp47
I6I24_RS20940	COG3299	homolog of phage Mu protein gp47
I6I24_RS20980	COG4386	tail sheath protein
I6I24_RS21025	COG4695	Portal protein
I6I24_RS21035	COG4626	Terminase
I6I24_RS21035	COG1802	Transcriptional regulator
I6I24_RS21065	COG3179	chitinase
I6I24_RS21090	COG1403	HNH endonuclease
I6I24_RS21100	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
I6I24_RS21105	COG4725	Belongs to the MT-A70-like family
I6I24_RS21115	COG1846	Transcriptional regulator
I6I24_RS21125	COG3646	Phage regulatory protein
I6I24_RS21150	COG5532	Uncharacterized conserved protein (DUF2303)
I6I24_RS21155	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
I6I24_RS21255	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
I6I24_RS21280	COG0534	Mate efflux family protein
I6I24_RS21445	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
I6I24_RS21460	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
I6I24_RS21475	COG1012	belongs to the aldehyde dehydrogenase family
I6I24_RS21475	COG1454	alcohol dehydrogenase
I6I24_RS21480	COG4656	Part of a membrane complex involved in electron transport
I6I24_RS21515	COG1289	transmembrane transporter activity
I6I24_RS21555	COG2925	Exonuclease
I6I24_RS21560	COG0531	amino acid
I6I24_RS21570	COG0583	DNA-binding transcription factor activity
I6I24_RS21575	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
I6I24_RS21735	COG2327	Polysaccharide pyruvyl transferase
I6I24_RS21740	COG2244	polysaccharide biosynthetic process
I6I24_RS21745	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
I6I24_RS21760	COG0297	glycogen (starch) synthase activity
I6I24_RS21770	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
I6I24_RS21775	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
I6I24_RS21780	COG0110	maltose O-acetyltransferase activity
I6I24_RS21785	COG1216	Glycosyl transferase, family 2
I6I24_RS21795	COG0438	transferase activity, transferring glycosyl groups
I6I24_RS21800	COG1045	serine acetyltransferase
I6I24_RS21805	COG0463	Glycosyl transferase, family 2
I6I24_RS21825	COG1253	flavin adenine dinucleotide binding
I6I24_RS21830	COG2982	Protein involved in outer membrane biogenesis
I6I24_RS21845	COG5001	Diguanylate cyclase
I6I24_RS21845	COG5002	protein histidine kinase activity
I6I24_RS21845	COG3447	MASE1 domain protein
I6I24_RS21850	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
I6I24_RS21855	COG0443	Heat shock 70 kDa protein
I6I24_RS21885	COG2205	protein histidine kinase activity
I6I24_RS21890	COG0745	RESPONSE REGULATOR receiver
I6I24_RS21910	COG0826	peptidase U32
I6I24_RS21935	COG1830	Aldolase
I6I24_RS21940	COG2211	Major facilitator Superfamily
I6I24_RS21945	COG1397	ADP-ribosylglycohydrolase
I6I24_RS21950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
I6I24_RS21955	COG2188	Transcriptional regulator
I6I24_RS21970	COG5455	response to cobalt ion
I6I24_RS21975	COG3539	Fimbrial protein
I6I24_RS21980	COG3188	usher protein
I6I24_RS21985	COG3121	Chaperone
I6I24_RS22010	COG4808	Protein conserved in bacteria
I6I24_RS22020	COG4807	Protein conserved in bacteria
I6I24_RS22030	COG3275	phosphorelay sensor kinase activity
I6I24_RS22045	COG1174	glycine betaine transport
I6I24_RS22050	COG1125	glycine betaine transport
I6I24_RS22055	COG1174	glycine betaine transport
I6I24_RS22060	COG1732	Glycine betaine
I6I24_RS22070	COG0277	FAD linked oxidase domain protein
I6I24_RS22075	COG1686	Belongs to the peptidase S11 family
I6I24_RS22085	COG0586	Pfam SNARE associated Golgi protein
I6I24_RS22090	COG1028	Short-chain dehydrogenase reductase Sdr
I6I24_RS22095	COG1538	Outer membrane efflux protein
I6I24_RS22110	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
I6I24_RS22115	COG0625	glutathione transferase activity
I6I24_RS22130	COG2271	Major facilitator Superfamily
I6I24_RS22145	COG1346	cytolysis
I6I24_RS22155	COG2949	membrane
I6I24_RS22195	COG2311	Membrane
I6I24_RS22215	COG1760	l-serine dehydratase
I6I24_RS22220	COG0560	Phosphoserine phosphatase
I6I24_RS22225	COG2271	Major facilitator Superfamily
I6I24_RS22230	COG4771	TonB-dependent receptor
I6I24_RS22235	COG0833	amino acid
I6I24_RS22240	COG0583	DNA-binding transcription factor activity
I6I24_RS22245	COG2855	membrane
I6I24_RS22255	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I6I24_RS22255	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
I6I24_RS22255	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I6I24_RS22260	COG1105	Belongs to the carbohydrate kinase PfkB family
I6I24_RS22295	COG0523	cobalamin synthesis protein
I6I24_RS22300	COG0671	phosphoesterase, PA-phosphatase related
I6I24_RS22305	COG0791	NLP P60 protein
I6I24_RS22310	COG2200	EAL domain
I6I24_RS22315	COG4166	transmembrane transport
I6I24_RS22320	COG4174	ABC transporter (Permease)
I6I24_RS22325	COG4239	(ABC) transporter, permease
I6I24_RS22330	COG4172	Belongs to the ABC transporter superfamily
I6I24_RS22340	COG2814	Major facilitator Superfamily
I6I24_RS22350	COG1061	Type III restriction enzyme res subunit
I6I24_RS22440	COG1403	HNH endonuclease
I6I24_RS22460	COG5301	cellulose 1,4-beta-cellobiosidase activity
I6I24_RS22475	COG2197	response regulator
I6I24_RS22480	COG3088	subunit of a heme lyase
I6I24_RS22480	COG4235	cytochrome complex assembly
I6I24_RS22490	COG1138	Cytochrome C-type biogenesis protein
I6I24_RS22500	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
I6I24_RS22505	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
I6I24_RS22510	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
I6I24_RS22515	COG4133	protoheme IX ABC transporter activity
I6I24_RS22520	COG3005	denitrification pathway
I6I24_RS22525	COG3043	anaerobic respiration
I6I24_RS22530	COG0348	domain, Protein
I6I24_RS22535	COG0437	4 iron, 4 sulfur cluster binding
I6I24_RS22545	COG3062	negative regulation of establishment of protein localization
I6I24_RS22550	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
I6I24_RS22550	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
I6I24_RS22560	COG4615	Cyclic peptide transporter
I6I24_RS22585	COG2198	Histidine kinase
I6I24_RS22585	COG0642	Histidine kinase
I6I24_RS22605	COG4948	Mandelate Racemase Muconate Lactonizing
I6I24_RS22635	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
I6I24_RS22640	COG2814	Major facilitator Superfamily
I6I24_RS22645	COG0583	DNA-binding transcription factor activity
I6I24_RS22650	COG0584	glycerophosphoryl diester phosphodiesterase
I6I24_RS22655	COG2271	Major facilitator Superfamily
I6I24_RS22660	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
I6I24_RS22670	COG0247	lactate metabolic process
I6I24_RS22690	COG2271	Major facilitator Superfamily
I6I24_RS22700	COG1414	Transcriptional regulator
I6I24_RS22790	COG1169	isochorismate synthase
I6I24_RS22795	COG4575	ribosome binding
I6I24_RS22800	COG2153	protein acetylation
I6I24_RS22810	COG0784	Response regulator, receiver
I6I24_RS22810	COG0835	chemotaxis
I6I24_RS22815	COG2304	oxidoreductase activity
I6I24_RS22830	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
I6I24_RS22835	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
I6I24_RS22845	COG0839	Belongs to the complex I subunit 6 family
I6I24_RS22895	COG0583	DNA-binding transcription factor activity
I6I24_RS22900	COG0436	Aminotransferase
I6I24_RS22910	COG0490	domain, Protein
I6I24_RS22910	COG0471	metal ion transport
I6I24_RS22915	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
I6I24_RS22940	COG1288	antiporter activity
I6I24_RS22945	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
I6I24_RS22950	COG3959	Transketolase, thiamine diphosphate binding domain
I6I24_RS22955	COG3037	sugar-specific permease SgaT UlaA
I6I24_RS22965	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
I6I24_RS22970	COG1609	Transcriptional regulator
I6I24_RS22980	COG0622	Phosphoesterase
I6I24_RS22985	COG0625	glutathione transferase activity
I6I24_RS22990	COG0625	glutathione transferase activity
I6I24_RS22995	COG1090	epimerase
I6I24_RS23030	COG0833	amino acid
I6I24_RS23035	COG3457	Alanine racemase
I6I24_RS23040	COG0531	amino acid
I6I24_RS23050	COG3829	transcription factor binding
I6I24_RS23055	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
I6I24_RS23060	COG1286	toxin biosynthetic process
I6I24_RS23065	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
I6I24_RS23070	COG0285	dihydrofolate synthase activity
I6I24_RS23080	COG0586	Pfam SNARE associated Golgi protein
I6I24_RS23090	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
I6I24_RS23115	COG3423	Transcriptional regulator
I6I24_RS23135	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
I6I24_RS23150	COG3101	peptidyl-lysine hydroxylation
I6I24_RS23155	COG0730	response to heat
I6I24_RS23180	COG2062	phosphohistidine phosphatase, SixA
I6I24_RS23195	COG3691	Protein conserved in bacteria
I6I24_RS23210	COG2116	formate transmembrane transporter activity
I6I24_RS23250	COG1560	Kdo2-lipid A biosynthetic process
I6I24_RS23260	COG0436	Aminotransferase
I6I24_RS23275	COG3961	Belongs to the TPP enzyme family
I6I24_RS23280	COG0667	Aldo Keto reductase
I6I24_RS23295	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
I6I24_RS23300	COG2199	diguanylate cyclase activity
I6I24_RS23300	COG2200	EAL domain
I6I24_RS23315	COG3415	Transposase
I6I24_RS23320	COG3415	Transposase
I6I24_RS23350	COG0583	DNA-binding transcription factor activity
I6I24_RS23360	COG2211	Major facilitator Superfamily
I6I24_RS23365	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
I6I24_RS23375	COG0583	DNA-binding transcription factor activity
I6I24_RS23380	COG0385	Bile acid
I6I24_RS23385	COG3530	Putative quorum-sensing-regulated virulence factor
I6I24_RS23410	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
I6I24_RS23465	COG4208	sulfate ABC transporter
I6I24_RS23485	COG2837	iron assimilation
I6I24_RS23625	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
I6I24_RS23635	COG5342	invasion associated locus B
I6I24_RS23650	COG0493	'glutamate synthase
I6I24_RS23650	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
I6I24_RS23810	COG1475	DNA binding
I6I24_RS24015	COG2805	Type II/IV secretion system protein
I6I24_RS24065	COG0741	lytic transglycosylase activity
I6I24_RS24080	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
I6I24_RS24265	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
I6I24_RS24330	COG1388	LysM domain
I6I24_RS24330	COG2373	Large extracellular alpha-helical protein
I6I24_RS24330	COG4932	domain protein
I6I24_RS24450	COG3204	pilus organization
I6I24_RS24460	COG2207	Transcriptional regulator
I6I24_RS24465	COG3204	pilus organization