locus-tag	class	description
CHD18_RS00030	COG4948	Mandelate Racemase Muconate Lactonizing
CHD18_RS00035	COG2271	Major facilitator Superfamily
CHD18_RS00040	COG0561	phosphatase activity
CHD18_RS00045	COG2186	Transcriptional regulator
CHD18_RS00050	COG3734	2-keto-3-deoxy-galactonokinase
CHD18_RS00055	COG0800	Aldolase
CHD18_RS00065	COG2271	Major facilitator Superfamily
CHD18_RS00070	COG2205	protein histidine kinase activity
CHD18_RS00070	COG2198	Histidine kinase
CHD18_RS00070	COG0784	Response regulator, receiver
CHD18_RS00075	COG1879	ABC-type sugar transport system periplasmic component
CHD18_RS00080	COG0745	RESPONSE REGULATOR receiver
CHD18_RS00085	COG3005	denitrification pathway
CHD18_RS00100	COG1858	cytochrome C peroxidase
CHD18_RS00110	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CHD18_RS00115	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CHD18_RS00120	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CHD18_RS00130	COG1138	Cytochrome C-type biogenesis protein
CHD18_RS00140	COG3088	subunit of a heme lyase
CHD18_RS00140	COG4235	cytochrome complex assembly
CHD18_RS00145	COG0823	Involved in the tonB-independent uptake of proteins
CHD18_RS00150	COG5645	(Lipo)protein
CHD18_RS00170	COG2149	membrane
CHD18_RS00180	COG0641	radical SAM
CHD18_RS00190	COG2610	gluconate transmembrane transporter activity
CHD18_RS00195	COG0583	DNA-binding transcription factor activity
CHD18_RS00205	COG2814	Major facilitator Superfamily
CHD18_RS00235	COG0028	Belongs to the TPP enzyme family
CHD18_RS00240	COG0440	acetolactate synthase activity
CHD18_RS00245	COG1349	DNA-binding transcription factor activity
CHD18_RS00255	COG0738	Major facilitator superfamily
CHD18_RS00305	COG2723	6-phospho-beta-galactosidase activity
CHD18_RS00325	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CHD18_RS00325	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHD18_RS00330	COG3715	PTS system
CHD18_RS00335	COG3716	PTS system mannose fructose sorbose family IID component
CHD18_RS00350	COG5464	transposase or invertase
CHD18_RS00380	COG1335	isochorismatase
CHD18_RS00390	COG3710	Transcriptional regulator
CHD18_RS00405	COG2771	luxR family
CHD18_RS00480	COG0582	viral genome integration into host DNA
CHD18_RS00490	COG2211	Major facilitator Superfamily
CHD18_RS00495	COG1501	Belongs to the glycosyl hydrolase 31 family
CHD18_RS00500	COG2982	Protein involved in outer membrane biogenesis
CHD18_RS00505	COG2233	PERMEase
CHD18_RS00510	COG0786	glutamate:sodium symporter activity
CHD18_RS00515	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CHD18_RS00520	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CHD18_RS00525	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CHD18_RS00545	COG2860	membrane
CHD18_RS00555	COG0583	DNA-binding transcription factor activity
CHD18_RS00560	COG1561	YicC-like family, N-terminal region
CHD18_RS00590	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CHD18_RS00620	COG1519	Transferase
CHD18_RS00625	COG0859	PFAM glycosyl transferase family 9
CHD18_RS00630	COG0438	transferase activity, transferring glycosyl groups
CHD18_RS00705	COG1216	Glycosyl transferase, family 2
CHD18_RS00710	COG2861	carbohydrate metabolic process
CHD18_RS00715	COG4942	peptidase
CHD18_RS00725	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CHD18_RS00730	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CHD18_RS00750	COG2271	Major facilitator Superfamily
CHD18_RS00765	COG1609	Transcriptional regulator
CHD18_RS00770	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CHD18_RS00780	COG2186	Transcriptional regulator
CHD18_RS00815	COG3722	fumarate hydratase activity
CHD18_RS00825	COG2213	PTS system mannitol-specific
CHD18_RS00825	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHD18_RS00830	COG0625	glutathione transferase activity
CHD18_RS00840	COG3276	selenocysteine insertion sequence binding
CHD18_RS00845	COG1940	carbohydrate kinase activity
CHD18_RS00850	COG1012	belongs to the aldehyde dehydrogenase family
CHD18_RS00865	COG0235	Class ii aldolase
CHD18_RS00870	COG3623	hexulose-6-phosphate isomerase
CHD18_RS00875	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CHD18_RS00880	COG1070	Carbohydrate kinase
CHD18_RS00885	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CHD18_RS00890	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CHD18_RS00895	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CHD18_RS00905	COG2731	YhcH YjgK YiaL family protein
CHD18_RS00915	COG1414	Transcriptional regulator
CHD18_RS00920	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CHD18_RS00925	COG3977	Valine--pyruvate aminotransferase
CHD18_RS00930	COG0366	Alpha amylase catalytic
CHD18_RS00935	COG2992	FlgJ-related protein
CHD18_RS00940	COG1609	Transcriptional regulator
CHD18_RS00940	COG2207	Transcriptional regulator
CHD18_RS00955	COG1070	Carbohydrate kinase
CHD18_RS00960	COG4682	membrane
CHD18_RS00965	COG3274	enterobacterial common antigen metabolic process
CHD18_RS01010	COG1278	Cold shock
CHD18_RS01015	COG2944	sequence-specific DNA binding
CHD18_RS01025	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CHD18_RS01030	COG2885	chlorophyll binding
CHD18_RS01035	COG0243	molybdopterin cofactor binding
CHD18_RS01040	COG0456	acetyltransferase
CHD18_RS01045	COG2818	Glycosylase
CHD18_RS01050	COG5571	outer membrane autotransporter
CHD18_RS01095	COG1609	Transcriptional regulator
CHD18_RS01110	COG0747	negative chemotaxis
CHD18_RS01115	COG0601	transmembrane transport
CHD18_RS01120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHD18_RS01125	COG0444	Belongs to the ABC transporter superfamily
CHD18_RS01130	COG4608	Belongs to the ABC transporter superfamily
CHD18_RS01135	COG0814	amino acid
CHD18_RS01175	COG1215	transferase activity, transferring glycosyl groups
CHD18_RS01180	COG1215	transferase activity, transferring glycosyl groups
CHD18_RS01200	COG2199	diguanylate cyclase activity
CHD18_RS01200	COG2200	EAL domain
CHD18_RS01215	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CHD18_RS01220	COG2200	EAL domain
CHD18_RS01225	COG2982	Protein involved in outer membrane biogenesis
CHD18_RS01230	COG0477	Major facilitator Superfamily
CHD18_RS01235	COG1295	ribonuclease BN
CHD18_RS01240	COG0583	DNA-binding transcription factor activity
CHD18_RS01245	COG2197	response regulator
CHD18_RS01265	COG2188	Transcriptional regulator
CHD18_RS01270	COG2222	sugar isomerase
CHD18_RS01275	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CHD18_RS01280	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CHD18_RS01290	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CHD18_RS01295	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CHD18_RS01335	COG0306	phosphate transporter
CHD18_RS01340	COG2081	HI0933 family
CHD18_RS01345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CHD18_RS01350	COG0842	Transport permease protein
CHD18_RS01350	COG1129	ABC transporter
CHD18_RS01355	COG0842	Transport permease protein
CHD18_RS01365	COG2091	lysine biosynthetic process via aminoadipic acid
CHD18_RS01370	COG0628	permease
CHD18_RS01385	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CHD18_RS01405	COG3714	YhhN family
CHD18_RS01415	COG3776	membrane
CHD18_RS01420	COG0742	ribosomal rna small subunit methyltransferase
CHD18_RS01425	COG0552	protein localization to endoplasmic reticulum
CHD18_RS01430	COG2884	Cell division ATP-binding protein ftsE
CHD18_RS01435	COG2177	Part of the ABC transporter FtsEX involved in
CHD18_RS01515	COG0584	glycerophosphoryl diester phosphodiesterase
CHD18_RS01525	COG0405	Gamma-glutamyltransferase
CHD18_RS01530	COG1735	metal-dependent hydrolase with the TIM-barrel fold
CHD18_RS01545	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CHD18_RS01550	COG1247	-acetyltransferase
CHD18_RS01555	COG0673	inositol 2-dehydrogenase activity
CHD18_RS01560	COG1741	Belongs to the pirin family
CHD18_RS01565	COG1609	Transcriptional regulator
CHD18_RS01570	COG3265	gluconokinase activity
CHD18_RS01575	COG2610	gluconate transmembrane transporter activity
CHD18_RS01610	COG0058	SHG alpha-glucan phosphorylase activity
CHD18_RS01615	COG1414	Transcriptional regulator
CHD18_RS01620	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CHD18_RS01625	COG0129	dihydroxy-acid dehydratase activity
CHD18_RS01635	COG0371	Dehydrogenase
CHD18_RS01650	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CHD18_RS01665	COG1349	DNA-binding transcription factor activity
CHD18_RS01675	COG0058	SHG alpha-glucan phosphorylase activity
CHD18_RS01680	COG1640	4-alpha-glucanotransferase
CHD18_RS01685	COG2610	gluconate transmembrane transporter activity
CHD18_RS01705	COG5464	transposase or invertase
CHD18_RS01720	COG1918	ferrous iron import across plasma membrane
CHD18_RS01730	COG2183	response to ionizing radiation
CHD18_RS01735	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CHD18_RS01755	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CHD18_RS01765	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CHD18_RS01770	COG1011	Hydrolase
CHD18_RS01780	COG0494	nUDIX hydrolase
CHD18_RS01785	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CHD18_RS01790	COG4972	Pilus assembly protein
CHD18_RS01795	COG3166	PFAM Fimbrial assembly family protein
CHD18_RS01810	COG4796	Type ii and iii secretion system protein
CHD18_RS01830	COG3266	domain, Protein
CHD18_RS01835	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CHD18_RS01840	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CHD18_RS01880	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CHD18_RS01915	COG1289	transmembrane transporter activity
CHD18_RS01925	COG1765	OsmC-like protein
CHD18_RS01930	COG3954	Phosphoribulokinase
CHD18_RS01940	COG0429	hydrolase of the alpha beta-hydrolase fold
CHD18_RS01955	COG0488	(ABC) transporter
CHD18_RS01970	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CHD18_RS01975	COG1047	Peptidyl-prolyl cis-trans
CHD18_RS01990	COG0545	Peptidyl-prolyl cis-trans isomerase
CHD18_RS01995	COG2964	Protein conserved in bacteria
CHD18_RS02065	COG0051	transcription antitermination factor activity, RNA binding
CHD18_RS02090	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CHD18_RS02170	COG0201	protein transport
CHD18_RS02210	COG0789	Transcriptional regulator
CHD18_RS02215	COG3036	rescue of stalled ribosome
CHD18_RS02245	COG0758	DNA mediated transformation
CHD18_RS02255	COG0551	DNA topoisomerase type I activity
CHD18_RS02275	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CHD18_RS02315	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CHD18_RS02320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CHD18_RS02325	COG1309	transcriptional regulator
CHD18_RS02340	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CHD18_RS02360	COG4145	pantothenate transmembrane transporter activity
CHD18_RS02365	COG3924	membrane
CHD18_RS02370	COG0439	Biotin carboxylase
CHD18_RS02375	COG0511	ligase activity, forming carbon-carbon bonds
CHD18_RS02390	COG0604	alcohol dehydrogenase
CHD18_RS02395	COG2199	diguanylate cyclase activity
CHD18_RS02395	COG2200	EAL domain
CHD18_RS02410	COG1077	Cell shape determining protein MreB Mrl
CHD18_RS02415	COG1792	Involved in formation and maintenance of cell shape
CHD18_RS02420	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CHD18_RS02435	COG3164	Protein of unknown function
CHD18_RS02440	COG0312	modulator of DNA gyrase
CHD18_RS02445	COG0583	DNA-binding transcription factor activity
CHD18_RS02465	COG2732	(Barnase) inhibitor
CHD18_RS02490	COG2188	Transcriptional regulator
CHD18_RS02500	COG0471	metal ion transport
CHD18_RS02505	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CHD18_RS02510	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CHD18_RS02515	COG3630	sodium ion export across plasma membrane
CHD18_RS02540	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CHD18_RS02545	COG3105	Protein conserved in bacteria
CHD18_RS02550	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CHD18_RS02575	COG0625	glutathione transferase activity
CHD18_RS02580	COG2969	positive regulation of protein catabolic process
CHD18_RS02610	COG2731	YhcH YjgK YiaL family protein
CHD18_RS02615	COG0402	S-adenosylhomocysteine deaminase activity
CHD18_RS02620	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CHD18_RS02625	COG4804	nuclease activity
CHD18_RS02630	COG0493	'glutamate synthase
CHD18_RS02635	COG0067	glutamate synthase
CHD18_RS02635	COG0069	glutamate synthase activity
CHD18_RS02635	COG0070	glutamate synthase
CHD18_RS02645	COG1242	4 iron, 4 sulfur cluster binding
CHD18_RS02650	COG2198	Histidine kinase
CHD18_RS02650	COG0784	Response regulator, receiver
CHD18_RS02650	COG5002	protein histidine kinase activity
CHD18_RS02655	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CHD18_RS02660	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CHD18_RS02665	COG0515	serine threonine protein kinase
CHD18_RS02675	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHD18_RS02700	COG1137	ATPase activity
CHD18_RS02705	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CHD18_RS02710	COG3117	lipopolysaccharide transmembrane transporter activity
CHD18_RS02715	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CHD18_RS02725	COG0530	calcium, potassium:sodium antiporter activity
CHD18_RS02730	COG1127	ABC transporter
CHD18_RS02735	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CHD18_RS02740	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CHD18_RS02745	COG2854	intermembrane phospholipid transfer
CHD18_RS02750	COG3113	response to antibiotic
CHD18_RS02755	COG5007	Belongs to the BolA IbaG family
CHD18_RS02765	COG3423	Transcriptional regulator
CHD18_RS02770	COG0142	geranyltranstransferase activity
CHD18_RS02785	COG0697	spore germination
CHD18_RS02795	COG2027	D-alanyl-D-alanine carboxypeptidase
CHD18_RS02805	COG1534	Rna-binding protein
CHD18_RS02825	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CHD18_RS02835	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CHD18_RS02900	COG0513	Belongs to the DEAD box helicase family
CHD18_RS02905	COG0814	amino acid
CHD18_RS02910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CHD18_RS02915	COG0826	peptidase U32
CHD18_RS02920	COG0826	peptidase U32
CHD18_RS02925	COG3154	lipid carrier protein
CHD18_RS02930	COG3153	acetyltransferase
CHD18_RS02945	COG0693	protein deglycase activity
CHD18_RS02950	COG0702	epimerase
CHD18_RS02955	COG2823	Periplasmic or secreted lipoprotein
CHD18_RS02975	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CHD18_RS02985	COG1063	alcohol dehydrogenase
CHD18_RS02990	COG3775	system Galactitol-specific IIC component
CHD18_RS03000	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHD18_RS03020	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHD18_RS03020	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CHD18_RS03020	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CHD18_RS03025	COG1105	Belongs to the carbohydrate kinase PfkB family
CHD18_RS03035	COG1349	DNA-binding transcription factor activity
CHD18_RS03040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CHD18_RS03045	COG2721	sulfolactate sulfo-lyase activity
CHD18_RS03055	COG2084	Dehydrogenase
CHD18_RS03060	COG1929	Belongs to the glycerate kinase type-1 family
CHD18_RS03075	COG0583	DNA-binding transcription factor activity
CHD18_RS03095	COG1882	Formate acetyltransferase
CHD18_RS03100	COG1760	l-serine dehydratase
CHD18_RS03105	COG0814	amino acid
CHD18_RS03120	COG1741	Belongs to the pirin family
CHD18_RS03125	COG0583	DNA-binding transcription factor activity
CHD18_RS03130	COG3152	Membrane
CHD18_RS03135	COG0435	Glutathione S-transferase
CHD18_RS03140	COG2259	Doxx family
CHD18_RS03150	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
CHD18_RS03155	COG4575	ribosome binding
CHD18_RS03160	COG1422	Protein of unknown function (DUF1090)
CHD18_RS03170	COG0586	Pfam SNARE associated Golgi protein
CHD18_RS03190	COG0673	inositol 2-dehydrogenase activity
CHD18_RS03195	COG2949	membrane
CHD18_RS03210	COG1902	pentaerythritol trinitrate reductase activity
CHD18_RS03210	COG0446	pyridine nucleotide-disulphide oxidoreductase
CHD18_RS03220	COG0840	transmembrane signaling receptor activity
CHD18_RS03225	COG0840	transmembrane signaling receptor activity
CHD18_RS03230	COG1695	Transcriptional regulator
CHD18_RS03235	COG2375	cellular response to nickel ion
CHD18_RS03245	COG4974	Belongs to the 'phage' integrase family
CHD18_RS03280	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CHD18_RS03315	COG4695	Portal protein
CHD18_RS03400	COG5301	cellulose 1,4-beta-cellobiosidase activity
CHD18_RS03470	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CHD18_RS03485	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CHD18_RS03495	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CHD18_RS03510	COG4991	sh3 domain protein
CHD18_RS03520	COG3025	triphosphatase activity
CHD18_RS03540	COG2268	Band 7 protein
CHD18_RS03545	COG1585	Membrane protein implicated in regulation of membrane protease activity
CHD18_RS03590	COG3384	dioxygenase
CHD18_RS03595	COG0754	glutathionylspermidine amidase activity
CHD18_RS03615	COG0494	nUDIX hydrolase
CHD18_RS03620	COG3151	Protein conserved in bacteria
CHD18_RS03625	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CHD18_RS03630	COG3150	esterase
CHD18_RS03640	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CHD18_RS03645	COG2249	NAD(P)H dehydrogenase (quinone) activity
CHD18_RS03660	COG3111	PFAM Bacterial OB fold (BOF) protein
CHD18_RS03665	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CHD18_RS03715	COG0471	metal ion transport
CHD18_RS03725	COG1979	alcohol dehydrogenase
CHD18_RS03730	COG2207	Transcriptional regulator
CHD18_RS03755	COG0848	biopolymer transport protein
CHD18_RS03760	COG1028	Short-chain dehydrogenase reductase Sdr
CHD18_RS03790	COG0840	transmembrane signaling receptor activity
CHD18_RS03805	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CHD18_RS03810	COG0437	4 iron, 4 sulfur cluster binding
CHD18_RS03815	COG5557	Pfam Polysulphide reductase, NrfD
CHD18_RS03820	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CHD18_RS03825	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CHD18_RS03830	COG1773	rubredoxin
CHD18_RS03840	COG0298	carbon dioxide binding
CHD18_RS03845	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CHD18_RS03855	COG0625	glutathione transferase activity
CHD18_RS03860	COG0754	glutathionylspermidine amidase activity
CHD18_RS03875	COG0246	Mannitol dehydrogenase
CHD18_RS03885	COG2271	Major facilitator Superfamily
CHD18_RS03910	COG1012	belongs to the aldehyde dehydrogenase family
CHD18_RS03915	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CHD18_RS03925	COG0531	amino acid
CHD18_RS03955	COG2301	Belongs to the HpcH HpaI aldolase family
CHD18_RS03960	COG2030	dehydratase
CHD18_RS03965	COG0427	acetyl-CoA hydrolase
CHD18_RS03980	COG1811	Na channel or pump
CHD18_RS03990	COG1982	Orn Lys Arg decarboxylase major
CHD18_RS03995	COG2211	Major facilitator Superfamily
CHD18_RS04025	COG3171	Protein conserved in bacteria
CHD18_RS04035	COG0252	asparaginase activity
CHD18_RS04045	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CHD18_RS04060	COG0762	integral membrane protein
CHD18_RS04065	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CHD18_RS04070	COG2805	Type II/IV secretion system protein
CHD18_RS04095	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CHD18_RS04100	COG2356	endonuclease I
CHD18_RS04110	COG2814	Major facilitator Superfamily
CHD18_RS04135	COG1166	arginine decarboxylase activity
CHD18_RS04145	COG2186	Transcriptional regulator
CHD18_RS04155	COG0246	Mannitol dehydrogenase
CHD18_RS04160	COG1063	alcohol dehydrogenase
CHD18_RS04165	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CHD18_RS04170	COG2731	YhcH YjgK YiaL family protein
CHD18_RS04175	COG2267	carboxylic ester hydrolase activity
CHD18_RS04190	COG0501	Belongs to the peptidase M48B family
CHD18_RS04195	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CHD18_RS04215	COG1122	ATPase activity
CHD18_RS04220	COG1122	ATPase activity
CHD18_RS04255	COG0191	fructose-bisphosphate aldolase activity
CHD18_RS04260	COG0668	transmembrane transport
CHD18_RS04270	COG2968	Membrane
CHD18_RS04290	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CHD18_RS04295	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CHD18_RS04320	COG0006	proline dipeptidase activity
CHD18_RS04325	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CHD18_RS04330	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CHD18_RS04360	COG2723	6-phospho-beta-galactosidase activity
CHD18_RS04370	COG1272	protein, Hemolysin III
CHD18_RS04440	COG4942	peptidase
CHD18_RS04495	COG3188	usher protein
CHD18_RS04530	COG0814	amino acid
CHD18_RS04545	COG0183	Belongs to the thiolase family
CHD18_RS04560	COG1028	Short-chain dehydrogenase reductase Sdr
CHD18_RS04565	COG2814	Major facilitator Superfamily
CHD18_RS04570	COG1794	racemase activity, acting on amino acids and derivatives
CHD18_RS04575	COG0583	DNA-binding transcription factor activity
CHD18_RS04585	COG1609	Transcriptional regulator
CHD18_RS04615	COG0667	Aldo Keto reductase
CHD18_RS04625	COG0861	Integral membrane protein TerC family
CHD18_RS04660	COG2165	general secretion pathway protein
CHD18_RS04665	COG4795	General secretion pathway protein
CHD18_RS04675	COG4967	type IV pilus modification protein PilV
CHD18_RS04680	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CHD18_RS04690	COG1074	ATP-dependent DNA helicase activity
CHD18_RS04695	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CHD18_RS04705	COG0860	N-Acetylmuramoyl-L-alanine amidase
CHD18_RS04720	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CHD18_RS04725	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CHD18_RS04730	COG2962	Rard protein
CHD18_RS04735	COG2166	iron-sulfur cluster assembly
CHD18_RS04740	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CHD18_RS04750	COG0583	DNA-binding transcription factor activity
CHD18_RS04755	COG2363	Small membrane protein
CHD18_RS04765	COG1349	DNA-binding transcription factor activity
CHD18_RS04785	COG0738	Major facilitator superfamily
CHD18_RS04790	COG0235	Class ii aldolase
CHD18_RS04795	COG1454	alcohol dehydrogenase
CHD18_RS04810	COG1760	l-serine dehydratase
CHD18_RS04815	COG0814	amino acid
CHD18_RS04820	COG1611	Belongs to the LOG family
CHD18_RS04840	COG3098	single-species biofilm formation
CHD18_RS04850	COG0716	FMN binding
CHD18_RS04860	COG2271	Major facilitator Superfamily
CHD18_RS04865	COG4948	Mandelate Racemase Muconate Lactonizing
CHD18_RS04870	COG4948	Mandelate Racemase Muconate Lactonizing
CHD18_RS04875	COG1929	Belongs to the glycerate kinase type-1 family
CHD18_RS04880	COG3850	Histidine kinase
CHD18_RS04880	COG3437	response regulator, receiver
CHD18_RS04880	COG2205	protein histidine kinase activity
CHD18_RS04880	COG4999	Histidine kinase
CHD18_RS04890	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CHD18_RS04915	COG3539	Fimbrial protein
CHD18_RS04920	COG3121	Chaperone
CHD18_RS04925	COG3188	usher protein
CHD18_RS04930	COG3539	Fimbrial protein
CHD18_RS04935	COG3956	TIGRFAM MazG family protein
CHD18_RS04950	COG0602	queuosine metabolic process
CHD18_RS04955	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CHD18_RS04955	COG0321	lipoyl(octanoyl) transferase activity
CHD18_RS04960	COG0720	synthase
CHD18_RS05000	COG1203	CRISPR-associated helicase, Cas3
CHD18_RS05015	COG1857	crispr-associated protein
CHD18_RS05030	COG1518	maintenance of DNA repeat elements
CHD18_RS05035	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CHD18_RS05040	COG2234	aminopeptidase activity
CHD18_RS05110	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CHD18_RS05115	COG0163	prenyltransferase activity
CHD18_RS05125	COG1349	DNA-binding transcription factor activity
CHD18_RS05130	COG2084	Dehydrogenase
CHD18_RS05140	COG0235	Class ii aldolase
CHD18_RS05145	COG3622	Belongs to the hyi family
CHD18_RS05150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CHD18_RS05155	COG2610	gluconate transmembrane transporter activity
CHD18_RS05165	COG0477	Major facilitator Superfamily
CHD18_RS05245	COG2207	Transcriptional regulator
CHD18_RS05335	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CHD18_RS05425	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CHD18_RS05430	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CHD18_RS05435	COG1121	(ABC) transporter
CHD18_RS05455	COG0309	Hydrogenase expression formation protein (HypE)
CHD18_RS05460	COG0409	Hydrogenase expression formation protein
CHD18_RS05465	COG0298	carbon dioxide binding
CHD18_RS05470	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CHD18_RS05490	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CHD18_RS05495	COG0651	ATP synthesis coupled electron transport
CHD18_RS05500	COG0650	Formate hydrogenlyase subunit 4
CHD18_RS05505	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CHD18_RS05505	COG3261	NADH dehydrogenase
CHD18_RS05510	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CHD18_RS05515	COG3260	NADH ubiquinone oxidoreductase 20
CHD18_RS05525	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CHD18_RS05535	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CHD18_RS05540	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CHD18_RS05560	COG0517	IMP dehydrogenase activity
CHD18_RS05560	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CHD18_RS05565	COG1349	DNA-binding transcription factor activity
CHD18_RS05570	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHD18_RS05575	COG1028	Short-chain dehydrogenase reductase Sdr
CHD18_RS05585	COG3732	PTS system glucitol sorbitol-specific
CHD18_RS05590	COG3730	PTS system glucitol sorbitol-specific
CHD18_RS05595	COG2951	lytic endotransglycosylase activity
CHD18_RS05605	COG1546	Belongs to the CinA family
CHD18_RS05630	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CHD18_RS05660	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CHD18_RS05665	COG1238	metal cluster binding
CHD18_RS05700	COG2814	Major facilitator Superfamily
CHD18_RS05705	COG1566	PFAM secretion protein HlyD family protein
CHD18_RS05710	COG1846	Transcriptional regulator
CHD18_RS05715	COG2814	Major facilitator Superfamily
CHD18_RS05765	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CHD18_RS05775	COG4575	ribosome binding
CHD18_RS05805	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CHD18_RS05810	COG0640	Transcriptional regulator
CHD18_RS05815	COG0401	homolog of Blt101
CHD18_RS05825	COG1652	LysM domain
CHD18_RS05830	COG1802	Transcriptional regulator
CHD18_RS05835	COG1113	amino acid transport
CHD18_RS05840	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CHD18_RS05845	COG1012	belongs to the aldehyde dehydrogenase family
CHD18_RS05850	COG0579	oxidoreductase
CHD18_RS05885	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CHD18_RS05900	COG2990	Protein conserved in bacteria
CHD18_RS05930	COG2819	hydrolase of the alpha beta superfamily
CHD18_RS06030	COG0582	viral genome integration into host DNA
CHD18_RS06040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CHD18_RS06065	COG2867	negative regulation of translational initiation
CHD18_RS06080	COG0497	DNA recombination
CHD18_RS06105	COG4536	flavin adenine dinucleotide binding
CHD18_RS06110	COG4137	Cytochrome C assembly protein
CHD18_RS06120	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CHD18_RS06145	COG2199	diguanylate cyclase activity
CHD18_RS06160	COG1605	Chorismate mutase
CHD18_RS06160	COG0287	Prephenate dehydrogenase
CHD18_RS06170	COG1605	Chorismate mutase
CHD18_RS06170	COG0077	Prephenate dehydratase
CHD18_RS06180	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CHD18_RS06185	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CHD18_RS06200	COG0542	response to heat
CHD18_RS06235	COG0477	Major facilitator Superfamily
CHD18_RS06240	COG5544	Lipoprotein
CHD18_RS06245	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CHD18_RS06255	COG3148	PFAM DTW domain containing protein
CHD18_RS06260	COG3118	belongs to the thioredoxin family
CHD18_RS06265	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CHD18_RS06285	COG0583	DNA-binding transcription factor activity
CHD18_RS06290	COG0513	Belongs to the DEAD box helicase family
CHD18_RS06300	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CHD18_RS06325	COG3086	response to oxidative stress
CHD18_RS06375	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CHD18_RS06380	COG0583	DNA-binding transcription factor activity
CHD18_RS06385	COG2223	nitrite transmembrane transporter activity
CHD18_RS06390	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CHD18_RS06395	COG1737	Transcriptional regulator
CHD18_RS06405	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CHD18_RS06405	COG1263	PTS System
CHD18_RS06410	COG0560	Phosphoserine phosphatase
CHD18_RS06435	COG2205	protein histidine kinase activity
CHD18_RS06440	COG3170	Tfp pilus assembly protein FimV
CHD18_RS06445	COG2204	response regulator
CHD18_RS06450	COG0347	Belongs to the P(II) protein family
CHD18_RS06455	COG3104	oligopeptide transport
CHD18_RS06465	COG0531	amino acid
CHD18_RS06470	COG3710	Transcriptional regulator
CHD18_RS06475	COG1017	nitric oxide dioxygenase activity
CHD18_RS06475	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CHD18_RS06485	COG2814	Major facilitator Superfamily
CHD18_RS06490	COG3711	transcriptional antiterminator
CHD18_RS06500	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CHD18_RS06545	COG0822	iron-sulfur transferase activity
CHD18_RS06565	COG0633	Ferredoxin
CHD18_RS06570	COG2975	iron-sulfur cluster assembly
CHD18_RS06600	COG2897	thiosulfate sulfurtransferase activity
CHD18_RS06605	COG2373	Large extracellular alpha-helical protein
CHD18_RS06610	COG4953	penicillin-binding protein 1C
CHD18_RS06615	COG0243	molybdopterin cofactor binding
CHD18_RS06620	COG0437	4 iron, 4 sulfur cluster binding
CHD18_RS06665	COG2976	Protein conserved in bacteria
CHD18_RS06680	COG1645	bacterial-type flagellum-dependent swarming motility
CHD18_RS06720	COG0516	GMP reductase activity
CHD18_RS06720	COG0517	IMP dehydrogenase activity
CHD18_RS06760	COG2200	EAL domain
CHD18_RS06775	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CHD18_RS06790	COG2233	PERMEase
CHD18_RS06800	COG1393	Belongs to the ArsC family
CHD18_RS06810	COG0628	permease
CHD18_RS06815	COG3835	regulator
CHD18_RS06820	COG2610	gluconate transmembrane transporter activity
CHD18_RS06825	COG1929	Belongs to the glycerate kinase type-1 family
CHD18_RS06830	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CHD18_RS06835	COG2716	regulation of RNA biosynthetic process
CHD18_RS06845	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CHD18_RS06855	COG2321	neutral zinc metallopeptidase
CHD18_RS06875	COG1393	Belongs to the ArsC family
CHD18_RS06885	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CHD18_RS06890	COG3850	Histidine kinase
CHD18_RS06900	COG0493	'glutamate synthase
CHD18_RS06900	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CHD18_RS06905	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CHD18_RS06915	COG5342	invasion associated locus B
CHD18_RS06925	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CHD18_RS07060	COG2837	iron assimilation
CHD18_RS07080	COG4208	sulfate ABC transporter
CHD18_RS07140	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHD18_RS07165	COG3530	Putative quorum-sensing-regulated virulence factor
CHD18_RS07170	COG0385	Bile acid
CHD18_RS07175	COG0583	DNA-binding transcription factor activity
CHD18_RS07185	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CHD18_RS07190	COG2211	Major facilitator Superfamily
CHD18_RS07200	COG0583	DNA-binding transcription factor activity
CHD18_RS07230	COG3415	Transposase
CHD18_RS07235	COG3415	Transposase
CHD18_RS07255	COG2199	diguanylate cyclase activity
CHD18_RS07255	COG2200	EAL domain
CHD18_RS07260	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CHD18_RS07275	COG0667	Aldo Keto reductase
CHD18_RS07285	COG3961	Belongs to the TPP enzyme family
CHD18_RS07300	COG0436	Aminotransferase
CHD18_RS07310	COG1560	Kdo2-lipid A biosynthetic process
CHD18_RS07415	COG0582	viral genome integration into host DNA
CHD18_RS07425	COG2116	formate transmembrane transporter activity
CHD18_RS07440	COG3691	Protein conserved in bacteria
CHD18_RS07455	COG2062	phosphohistidine phosphatase, SixA
CHD18_RS07480	COG0730	response to heat
CHD18_RS07485	COG3101	peptidyl-lysine hydroxylation
CHD18_RS07500	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CHD18_RS07520	COG3423	Transcriptional regulator
CHD18_RS07545	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CHD18_RS07555	COG0586	Pfam SNARE associated Golgi protein
CHD18_RS07565	COG0285	dihydrofolate synthase activity
CHD18_RS07570	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CHD18_RS07575	COG1286	toxin biosynthetic process
CHD18_RS07580	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CHD18_RS07585	COG3829	transcription factor binding
CHD18_RS07595	COG0531	amino acid
CHD18_RS07600	COG3457	Alanine racemase
CHD18_RS07605	COG0833	amino acid
CHD18_RS07645	COG1090	epimerase
CHD18_RS07650	COG0625	glutathione transferase activity
CHD18_RS07655	COG0625	glutathione transferase activity
CHD18_RS07660	COG0622	Phosphoesterase
CHD18_RS07670	COG1609	Transcriptional regulator
CHD18_RS07680	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHD18_RS07690	COG3037	sugar-specific permease SgaT UlaA
CHD18_RS07695	COG3959	Transketolase, thiamine diphosphate binding domain
CHD18_RS07700	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CHD18_RS07705	COG1288	antiporter activity
CHD18_RS07745	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CHD18_RS07750	COG0490	domain, Protein
CHD18_RS07750	COG0471	metal ion transport
CHD18_RS07765	COG0436	Aminotransferase
CHD18_RS07775	COG0583	DNA-binding transcription factor activity
CHD18_RS07825	COG0839	Belongs to the complex I subunit 6 family
CHD18_RS07835	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CHD18_RS07845	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CHD18_RS07860	COG2304	oxidoreductase activity
CHD18_RS07865	COG0784	Response regulator, receiver
CHD18_RS07865	COG0835	chemotaxis
CHD18_RS07875	COG2153	protein acetylation
CHD18_RS07880	COG4575	ribosome binding
CHD18_RS07885	COG1169	isochorismate synthase
CHD18_RS07975	COG1414	Transcriptional regulator
CHD18_RS07985	COG2271	Major facilitator Superfamily
CHD18_RS08010	COG0247	lactate metabolic process
CHD18_RS08020	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CHD18_RS08025	COG2271	Major facilitator Superfamily
CHD18_RS08030	COG0584	glycerophosphoryl diester phosphodiesterase
CHD18_RS08035	COG0583	DNA-binding transcription factor activity
CHD18_RS08040	COG2814	Major facilitator Superfamily
CHD18_RS08045	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CHD18_RS08075	COG4948	Mandelate Racemase Muconate Lactonizing
CHD18_RS08100	COG2198	Histidine kinase
CHD18_RS08100	COG0642	Histidine kinase
CHD18_RS08130	COG4615	Cyclic peptide transporter
CHD18_RS08140	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
CHD18_RS08140	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CHD18_RS08145	COG3062	negative regulation of establishment of protein localization
CHD18_RS08155	COG0437	4 iron, 4 sulfur cluster binding
CHD18_RS08160	COG0348	domain, Protein
CHD18_RS08170	COG3043	anaerobic respiration
CHD18_RS08175	COG3005	denitrification pathway
CHD18_RS08185	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CHD18_RS08190	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CHD18_RS08195	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CHD18_RS08205	COG1138	Cytochrome C-type biogenesis protein
CHD18_RS08215	COG4235	cytochrome complex assembly
CHD18_RS08215	COG3088	subunit of a heme lyase
CHD18_RS08220	COG2197	response regulator
CHD18_RS08240	COG5301	cellulose 1,4-beta-cellobiosidase activity
CHD18_RS08290	COG1061	Type III restriction enzyme res subunit
CHD18_RS08300	COG2814	Major facilitator Superfamily
CHD18_RS08315	COG4172	Belongs to the ABC transporter superfamily
CHD18_RS08320	COG4239	(ABC) transporter, permease
CHD18_RS08325	COG4174	ABC transporter (Permease)
CHD18_RS08330	COG4166	transmembrane transport
CHD18_RS08335	COG2200	EAL domain
CHD18_RS08345	COG0791	NLP P60 protein
CHD18_RS08355	COG0671	phosphoesterase, PA-phosphatase related
CHD18_RS08360	COG0523	cobalamin synthesis protein
CHD18_RS08400	COG1105	Belongs to the carbohydrate kinase PfkB family
CHD18_RS08405	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CHD18_RS08405	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CHD18_RS08405	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CHD18_RS08415	COG2855	membrane
CHD18_RS08420	COG0583	DNA-binding transcription factor activity
CHD18_RS08425	COG0833	amino acid
CHD18_RS08435	COG4771	TonB-dependent receptor
CHD18_RS08440	COG2271	Major facilitator Superfamily
CHD18_RS08445	COG0560	Phosphoserine phosphatase
CHD18_RS08450	COG1760	l-serine dehydratase
CHD18_RS08475	COG2311	Membrane
CHD18_RS08515	COG2949	membrane
CHD18_RS08525	COG1346	cytolysis
CHD18_RS08540	COG2271	Major facilitator Superfamily
CHD18_RS08555	COG0625	glutathione transferase activity
CHD18_RS08560	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CHD18_RS08575	COG1538	Outer membrane efflux protein
CHD18_RS08580	COG1028	Short-chain dehydrogenase reductase Sdr
CHD18_RS08585	COG0586	Pfam SNARE associated Golgi protein
CHD18_RS08600	COG1686	Belongs to the peptidase S11 family
CHD18_RS08605	COG0277	FAD linked oxidase domain protein
CHD18_RS08615	COG1732	Glycine betaine
CHD18_RS08620	COG1174	glycine betaine transport
CHD18_RS08625	COG1125	glycine betaine transport
CHD18_RS08630	COG1174	glycine betaine transport
CHD18_RS08645	COG3275	phosphorelay sensor kinase activity
CHD18_RS08655	COG4807	Protein conserved in bacteria
CHD18_RS08665	COG4808	Protein conserved in bacteria
CHD18_RS08690	COG3121	Chaperone
CHD18_RS08695	COG3188	usher protein
CHD18_RS08700	COG3539	Fimbrial protein
CHD18_RS08705	COG5455	response to cobalt ion
CHD18_RS08720	COG2188	Transcriptional regulator
CHD18_RS08725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CHD18_RS08730	COG1397	ADP-ribosylglycohydrolase
CHD18_RS08740	COG1830	Aldolase
CHD18_RS08765	COG0826	peptidase U32
CHD18_RS08790	COG0745	RESPONSE REGULATOR receiver
CHD18_RS08795	COG2205	protein histidine kinase activity
CHD18_RS08825	COG0443	Heat shock 70 kDa protein
CHD18_RS08835	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CHD18_RS08840	COG5002	protein histidine kinase activity
CHD18_RS08840	COG5001	Diguanylate cyclase
CHD18_RS08840	COG3447	MASE1 domain protein
CHD18_RS08855	COG2982	Protein involved in outer membrane biogenesis
CHD18_RS08860	COG1253	flavin adenine dinucleotide binding
CHD18_RS08885	COG0463	Glycosyl transferase, family 2
CHD18_RS08890	COG1045	serine acetyltransferase
CHD18_RS08895	COG0438	transferase activity, transferring glycosyl groups
CHD18_RS08905	COG1216	Glycosyl transferase, family 2
CHD18_RS08910	COG0110	maltose O-acetyltransferase activity
CHD18_RS08915	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CHD18_RS08920	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CHD18_RS08930	COG0297	glycogen (starch) synthase activity
CHD18_RS08945	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CHD18_RS08950	COG2244	polysaccharide biosynthetic process
CHD18_RS08955	COG2327	Polysaccharide pyruvyl transferase
CHD18_RS09000	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CHD18_RS09025	COG0463	Glycosyl transferase, family 2
CHD18_RS09050	COG0438	transferase activity, transferring glycosyl groups
CHD18_RS09135	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CHD18_RS09140	COG0583	DNA-binding transcription factor activity
CHD18_RS09150	COG0531	amino acid
CHD18_RS09155	COG2925	Exonuclease
CHD18_RS09200	COG1289	transmembrane transporter activity
CHD18_RS09235	COG4656	Part of a membrane complex involved in electron transport
CHD18_RS09240	COG1012	belongs to the aldehyde dehydrogenase family
CHD18_RS09240	COG1454	alcohol dehydrogenase
CHD18_RS09255	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
CHD18_RS09270	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CHD18_RS09400	COG1122	ATPase activity
CHD18_RS09435	COG0640	Transcriptional regulator
CHD18_RS09440	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CHD18_RS09455	COG0798	PFAM Bile acid sodium symporter
CHD18_RS09475	COG0534	Mate efflux family protein
CHD18_RS09490	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CHD18_RS09535	COG0582	viral genome integration into host DNA
CHD18_RS09585	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CHD18_RS09595	COG1418	mRNA catabolic process
CHD18_RS09600	COG0270	DNA (cytosine-5-)-methyltransferase activity
CHD18_RS09605	COG3727	T/G mismatch-specific endonuclease activity
CHD18_RS09610	COG0697	spore germination
CHD18_RS09615	COG2354	Protein conserved in bacteria
CHD18_RS09620	COG5475	Uncharacterized small protein (DUF2158)
CHD18_RS09725	COG0425	Belongs to the sulfur carrier protein TusA family
CHD18_RS09780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHD18_RS09790	COG0765	amino acid transport
CHD18_RS09795	COG1126	abc transporter atp-binding protein
CHD18_RS09800	COG2197	response regulator
CHD18_RS09815	COG2197	response regulator
CHD18_RS09860	COG3012	SEC-C Motif Domain Protein
CHD18_RS09860	COG3318	Belongs to the UPF0149 family
CHD18_RS09865	COG0814	amino acid
CHD18_RS09875	COG1528	Iron-storage protein
CHD18_RS09890	COG1528	Iron-storage protein
CHD18_RS09900	COG1172	Belongs to the binding-protein-dependent transport system permease family
CHD18_RS09995	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CHD18_RS10010	COG3102	Protein conserved in bacteria
CHD18_RS10035	COG3788	relative of glutathione S-transferase, MAPEG superfamily
CHD18_RS10040	COG1801	Protein of unknown function DUF72
CHD18_RS10045	COG1335	isochorismatase
CHD18_RS10055	COG0494	nUDIX hydrolase
CHD18_RS10090	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CHD18_RS10100	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CHD18_RS10105	COG0739	heme binding
CHD18_RS10115	COG1560	Kdo2-lipid A biosynthetic process
CHD18_RS10125	COG1737	Transcriptional regulator
CHD18_RS10135	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CHD18_RS10140	COG0129	dihydroxy-acid dehydratase activity
CHD18_RS10145	COG0800	Aldolase
CHD18_RS10155	COG3141	response to X-ray
CHD18_RS10165	COG2979	Protein of unknown function (DUF533)
CHD18_RS10170	COG1770	oligopeptidase
CHD18_RS10175	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CHD18_RS10180	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CHD18_RS10190	COG2372	response to copper ion
CHD18_RS10195	COG1276	copper resistance
CHD18_RS10210	COG0582	viral genome integration into host DNA
CHD18_RS10215	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CHD18_RS10365	COG5562	phage envelope protein
CHD18_RS10400	COG3008	intermembrane lipid transfer
CHD18_RS10405	COG2995	paraquat-inducible protein a
CHD18_RS10410	COG1956	GAF domain-containing protein
CHD18_RS10430	COG2814	Major facilitator Superfamily
CHD18_RS10435	COG1414	Transcriptional regulator
CHD18_RS10465	COG0768	penicillin binding
CHD18_RS10470	COG2226	methyltransferase
CHD18_RS10490	COG3716	PTS system mannose fructose sorbose family IID component
CHD18_RS10495	COG3715	PTS system
CHD18_RS10500	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHD18_RS10500	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CHD18_RS10510	COG1253	flavin adenine dinucleotide binding
CHD18_RS10515	COG2200	EAL domain
CHD18_RS10520	COG1760	l-serine dehydratase
CHD18_RS10540	COG0251	oxidation-reduction process
CHD18_RS10545	COG1199	ATP-dependent helicase activity
CHD18_RS10555	COG3065	identical protein binding
CHD18_RS10570	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CHD18_RS10580	COG2894	cell division
CHD18_RS10595	COG0179	Fumarylacetoacetate (FAA) hydrolase
CHD18_RS10635	COG2719	SpoVR family
CHD18_RS10655	COG1619	proteins homologs of microcin C7 resistance protein MccF
CHD18_RS10680	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CHD18_RS10690	COG1294	oxidase, subunit
CHD18_RS10695	COG1271	oxidase subunit
CHD18_RS10700	COG1773	rubredoxin
CHD18_RS10705	COG1999	signal sequence binding
CHD18_RS10710	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CHD18_RS10715	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
CHD18_RS10725	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CHD18_RS10750	COG0012	GTP binding
CHD18_RS10765	COG0659	secondary active sulfate transmembrane transporter activity
CHD18_RS10815	COG0387	Pfam Sodium calcium exchanger
CHD18_RS10820	COG4572	Cation transport regulator
CHD18_RS10825	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CHD18_RS10830	COG4932	domain protein
CHD18_RS10835	COG2197	response regulator
CHD18_RS10840	COG3850	Histidine kinase
CHD18_RS10850	COG2223	nitrite transmembrane transporter activity
CHD18_RS10855	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CHD18_RS10860	COG1140	nitrate reductase beta subunit
CHD18_RS10865	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CHD18_RS10870	COG2181	nitrate reductase activity
CHD18_RS10910	COG0788	formyltetrahydrofolate deformylase activity
CHD18_RS10920	COG1752	Esterase of the alpha-beta hydrolase superfamily
CHD18_RS10925	COG0745	RESPONSE REGULATOR receiver
CHD18_RS10930	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CHD18_RS10945	COG1454	alcohol dehydrogenase
CHD18_RS10945	COG1012	belongs to the aldehyde dehydrogenase family
CHD18_RS10950	COG2095	MarC family integral membrane protein
CHD18_RS10985	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CHD18_RS11000	COG2350	Protein conserved in bacteria
CHD18_RS11025	COG0727	PFAM Uncharacterised protein family (UPF0153)
CHD18_RS11030	COG3047	cAMP biosynthetic process
CHD18_RS11035	COG3546	catalase activity
CHD18_RS11040	COG3685	Protein conserved in bacteria
CHD18_RS11045	COG3685	Protein conserved in bacteria
CHD18_RS11050	COG3729	General stress protein
CHD18_RS11065	COG0134	indole-3-glycerol-phosphate synthase activity
CHD18_RS11065	COG0135	phosphoribosylanthranilate isomerase activity
CHD18_RS11090	COG0009	L-threonylcarbamoyladenylate synthase
CHD18_RS11105	COG1028	Short-chain dehydrogenase reductase Sdr
CHD18_RS11110	COG0616	signal peptide processing
CHD18_RS11160	COG0671	phosphoesterase, PA-phosphatase related
CHD18_RS11170	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CHD18_RS11175	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CHD18_RS11195	COG1349	DNA-binding transcription factor activity
CHD18_RS11205	COG5001	Diguanylate cyclase
CHD18_RS11220	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CHD18_RS11220	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CHD18_RS11275	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CHD18_RS11280	COG1842	Phage shock protein A
CHD18_RS11290	COG1983	PspC domain protein
CHD18_RS11300	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CHD18_RS11305	COG3106	COG3106 Predicted ATPase
CHD18_RS11325	COG4948	Mandelate Racemase Muconate Lactonizing
CHD18_RS11330	COG2866	Carboxypeptidase
CHD18_RS11335	COG4166	transmembrane transport
CHD18_RS11345	COG0583	DNA-binding transcription factor activity
CHD18_RS11350	COG0656	L-ascorbic acid biosynthetic process
CHD18_RS11355	COG1028	Short-chain dehydrogenase reductase Sdr
CHD18_RS11360	COG1309	transcriptional regulator
CHD18_RS11395	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CHD18_RS11415	COG0668	transmembrane transport
CHD18_RS11420	COG3182	Iron-regulated membrane protein
CHD18_RS11440	COG2840	Smr protein MutS2
CHD18_RS11450	COG0840	transmembrane signaling receptor activity
CHD18_RS11465	COG0513	Belongs to the DEAD box helicase family
CHD18_RS11480	COG2076	Multidrug Resistance protein
CHD18_RS11510	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CHD18_RS11510	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CHD18_RS11510	COG0674	pyruvate-flavodoxin oxidoreductase activity
CHD18_RS11510	COG1013	pyruvate-flavodoxin oxidoreductase activity
CHD18_RS11520	COG3042	response to heat
CHD18_RS11525	COG3187	Heat shock protein
CHD18_RS11530	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CHD18_RS11535	COG2911	Protein conserved in bacteria
CHD18_RS11545	COG3784	Protein of unknown function (DUF1318)
CHD18_RS11560	COG1643	Atp-dependent helicase
CHD18_RS11565	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CHD18_RS11570	COG3038	cytochrome b561
CHD18_RS11575	COG0500	methyltransferase
CHD18_RS11585	COG0765	amino acid transport
CHD18_RS11595	COG0765	amino acid transport
CHD18_RS11600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHD18_RS11640	COG0840	transmembrane signaling receptor activity
CHD18_RS11645	COG0583	DNA-binding transcription factor activity
CHD18_RS11650	COG5383	Protein conserved in bacteria
CHD18_RS11655	COG2272	Belongs to the type-B carboxylesterase lipase family
CHD18_RS11660	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CHD18_RS11665	COG2353	YceI-like domain
CHD18_RS11680	COG1349	DNA-binding transcription factor activity
CHD18_RS11685	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CHD18_RS11690	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHD18_RS11695	COG0434	BtpA family
CHD18_RS11700	COG3775	system Galactitol-specific IIC component
CHD18_RS11705	COG3414	Phosphotransferase system galactitol-specific IIB component
CHD18_RS11715	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CHD18_RS11720	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CHD18_RS11725	COG1275	C4-dicarboxylate transporter malic acid transport protein
CHD18_RS11730	COG0500	methyltransferase
CHD18_RS11740	COG3135	benzoate transporter
CHD18_RS11745	COG1396	sequence-specific DNA binding
CHD18_RS11750	COG0826	peptidase U32
CHD18_RS11775	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
CHD18_RS11780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CHD18_RS11820	COG3238	Protein conserved in bacteria
CHD18_RS11830	COG2130	NADP-dependent
CHD18_RS11835	COG1802	Transcriptional regulator
CHD18_RS11840	COG4772	TonB-dependent receptor
CHD18_RS11880	COG2181	nitrate reductase activity
CHD18_RS11885	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CHD18_RS11890	COG1140	nitrate reductase beta subunit
CHD18_RS11895	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CHD18_RS11935	COG3383	formate dehydrogenase (NAD+) activity
CHD18_RS11935	COG0243	molybdopterin cofactor binding
CHD18_RS11940	COG0243	molybdopterin cofactor binding
CHD18_RS11940	COG3383	formate dehydrogenase (NAD+) activity
CHD18_RS11945	COG0437	4 iron, 4 sulfur cluster binding
CHD18_RS11950	COG2864	formate dehydrogenase
CHD18_RS11955	COG1064	alcohol dehydrogenase
CHD18_RS11975	COG1764	response to oxidative stress
CHD18_RS11990	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CHD18_RS12005	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CHD18_RS12010	COG1757	Na H antiporter
CHD18_RS12015	COG1609	Transcriptional regulator
CHD18_RS12055	COG0251	oxidation-reduction process
CHD18_RS12060	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CHD18_RS12085	COG2271	Major facilitator Superfamily
CHD18_RS12090	COG1063	alcohol dehydrogenase
CHD18_RS12095	COG2186	Transcriptional regulator
CHD18_RS12105	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CHD18_RS12110	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CHD18_RS12135	COG1773	rubredoxin
CHD18_RS12160	COG3781	membrane
CHD18_RS12175	COG1012	belongs to the aldehyde dehydrogenase family
CHD18_RS12180	COG0583	DNA-binding transcription factor activity
CHD18_RS12220	COG2814	Major facilitator Superfamily
CHD18_RS12230	COG3111	PFAM Bacterial OB fold (BOF) protein
CHD18_RS12235	COG1546	Belongs to the CinA family
CHD18_RS12240	COG3729	General stress protein
CHD18_RS12250	COG4221	oxidoreductase activity
CHD18_RS12255	COG1802	Transcriptional regulator
CHD18_RS12270	COG0477	Major facilitator Superfamily
CHD18_RS12275	COG1063	alcohol dehydrogenase
CHD18_RS12295	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CHD18_RS12310	COG0243	molybdopterin cofactor binding
CHD18_RS12315	COG0243	molybdopterin cofactor binding
CHD18_RS12320	COG0437	4 iron, 4 sulfur cluster binding
CHD18_RS12325	COG3302	dmso reductase anchor subunit
CHD18_RS12365	COG1940	carbohydrate kinase activity
CHD18_RS12375	COG0583	DNA-binding transcription factor activity
CHD18_RS12380	COG2814	Major facilitator Superfamily
CHD18_RS12390	COG3591	Belongs to the peptidase S1B family
CHD18_RS12410	COG0628	permease
CHD18_RS12415	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CHD18_RS12420	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CHD18_RS12430	COG0531	amino acid
CHD18_RS12435	COG3136	membrane protein required for alginate biosynthesis
CHD18_RS12440	COG0745	RESPONSE REGULATOR receiver
CHD18_RS12450	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CHD18_RS12455	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CHD18_RS12460	COG2205	protein histidine kinase activity
CHD18_RS12485	COG5339	Protein conserved in bacteria
CHD18_RS12490	COG1263	PTS System
CHD18_RS12490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CHD18_RS12505	COG0673	inositol 2-dehydrogenase activity
CHD18_RS12555	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CHD18_RS12565	COG0625	glutathione transferase activity
CHD18_RS12585	COG3895	Periplasmic Protein
CHD18_RS12610	COG1566	PFAM secretion protein HlyD family protein
CHD18_RS12625	COG4989	oxidoreductase activity
CHD18_RS12630	COG3313	Fe-S protein
CHD18_RS12635	COG1309	transcriptional regulator
CHD18_RS12640	COG1902	pentaerythritol trinitrate reductase activity
CHD18_RS12660	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CHD18_RS12665	COG0791	NLP P60 protein
CHD18_RS12690	COG0583	DNA-binding transcription factor activity
CHD18_RS12695	COG2814	Major facilitator Superfamily
CHD18_RS12700	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CHD18_RS12705	COG0307	riboflavin synthase, alpha
CHD18_RS12890	COG0789	Transcriptional regulator
CHD18_RS12895	COG3272	Protein of unknown function (DUF1722)
CHD18_RS12930	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CHD18_RS12940	COG2267	carboxylic ester hydrolase activity
CHD18_RS12945	COG0531	amino acid
CHD18_RS12970	COG1376	ErfK ybiS ycfS ynhG family protein
CHD18_RS12985	COG0719	Fe-S assembly protein
CHD18_RS12990	COG0396	ATPase activity
CHD18_RS12995	COG0719	Fe-S assembly protein
CHD18_RS13000	COG0316	Belongs to the HesB IscA family
CHD18_RS13005	COG1823	symporter activity
CHD18_RS13015	COG2050	protein possibly involved in aromatic compounds catabolism
CHD18_RS13020	COG0277	FAD linked oxidase domain protein
CHD18_RS13020	COG0247	lactate metabolic process
CHD18_RS13025	COG0628	permease
CHD18_RS13040	COG0738	Major facilitator superfamily
CHD18_RS13045	COG2271	Major facilitator Superfamily
CHD18_RS13060	COG4670	ketone body catabolic process
CHD18_RS13065	COG1960	acyl-CoA dehydrogenase activity
CHD18_RS13070	COG2207	Transcriptional regulator
CHD18_RS13070	COG1917	Cupin 2, conserved barrel domain protein
CHD18_RS13075	COG2086	electron transfer activity
CHD18_RS13080	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CHD18_RS13085	COG0644	oxidoreductase
CHD18_RS13090	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CHD18_RS13095	COG0318	PFAM AMP-dependent synthetase and ligase
CHD18_RS13100	COG0574	Belongs to the PEP-utilizing enzyme family
CHD18_RS13100	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CHD18_RS13115	COG4256	Hemin uptake protein
CHD18_RS13120	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CHD18_RS13130	COG0791	NLP P60 protein
CHD18_RS13140	COG0386	Belongs to the glutathione peroxidase family
CHD18_RS13205	COG3137	Salt-induced outer membrane protein
CHD18_RS13210	COG1105	Belongs to the carbohydrate kinase PfkB family
CHD18_RS13220	COG3001	Fructosamine kinase
CHD18_RS13230	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CHD18_RS13235	COG1988	membrane-bound metal-dependent
CHD18_RS13240	COG1823	symporter activity
CHD18_RS13250	COG0753	catalase activity
CHD18_RS13260	COG1486	melibiose metabolic process
CHD18_RS13265	COG1917	Cupin 2, conserved barrel domain protein
CHD18_RS13265	COG2169	Transcriptional regulator
CHD18_RS13270	COG1447	Phosphotransferase system cellobiose-specific component IIA
CHD18_RS13275	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CHD18_RS13280	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CHD18_RS13290	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CHD18_RS13300	COG0322	excinuclease ABC activity
CHD18_RS13305	COG3678	ATP-independent chaperone mediated protein folding
CHD18_RS13350	COG0494	nUDIX hydrolase
CHD18_RS13375	COG0778	Nitroreductase
CHD18_RS13380	COG0616	signal peptide processing
CHD18_RS13385	COG0252	asparaginase activity
CHD18_RS13390	COG1335	isochorismatase
CHD18_RS13395	COG3139	Protein of unknown function (DUF1315)
CHD18_RS13420	COG0656	L-ascorbic acid biosynthetic process
CHD18_RS13425	COG0641	radical SAM
CHD18_RS13430	COG3713	MltA-interacting MipA family protein
CHD18_RS13435	COG2766	serine protein kinase
CHD18_RS13445	COG2199	diguanylate cyclase activity
CHD18_RS13450	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CHD18_RS13465	COG2207	Transcriptional regulator
CHD18_RS13470	COG2807	transmembrane transport
CHD18_RS13475	COG3189	MarR family transcriptional regulator
CHD18_RS13485	COG3042	response to heat
CHD18_RS13495	COG2261	transglycosylase associated protein
CHD18_RS13515	COG3615	Tellurite resistance protein tehB
CHD18_RS13530	COG1605	Chorismate mutase
CHD18_RS13545	COG0789	Transcriptional regulator
CHD18_RS13560	COG3443	Belongs to the bacterial solute-binding protein 9 family
CHD18_RS13575	COG0668	transmembrane transport
CHD18_RS13580	COG1124	(ABC) transporter
CHD18_RS13610	COG3038	cytochrome b561
CHD18_RS13620	COG0071	Belongs to the small heat shock protein (HSP20) family
CHD18_RS13710	COG0538	isocitrate dehydrogenase activity
CHD18_RS13730	COG4166	transmembrane transport
CHD18_RS13845	COG0740	serine-type endopeptidase activity
CHD18_RS13890	COG3179	chitinase
CHD18_RS13915	COG1403	HNH endonuclease
CHD18_RS13925	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
CHD18_RS13935	COG4725	Belongs to the MT-A70-like family
CHD18_RS13945	COG1846	Transcriptional regulator
CHD18_RS13955	COG3646	Phage regulatory protein
CHD18_RS14000	COG5532	Uncharacterized conserved protein (DUF2303)
CHD18_RS14010	COG0582	viral genome integration into host DNA
CHD18_RS14015	COG0538	isocitrate dehydrogenase activity
CHD18_RS14045	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CHD18_RS14060	COG2850	peptidyl-arginine hydroxylation
CHD18_RS14090	COG1177	transmembrane transport
CHD18_RS14110	COG4591	ABC-type transport system involved in lipoprotein release permease component
CHD18_RS14115	COG1136	(ABC) transporter
CHD18_RS14120	COG4591	ABC-type transport system involved in lipoprotein release permease component
CHD18_RS14125	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CHD18_RS14130	COG1388	LysM domain
CHD18_RS14130	COG1376	ErfK ybiS ycfS ynhG family protein
CHD18_RS14140	COG1309	transcriptional regulator
CHD18_RS14145	COG3134	Outer membrane lipoprotein
CHD18_RS14150	COG1252	NADH dehydrogenase
CHD18_RS14175	COG5633	Lipoprotein
CHD18_RS14180	COG0537	adenosine 5'-monophosphoramidase activity
CHD18_RS14185	COG4773	Receptor
CHD18_RS14195	COG0084	hydrolase, TatD family'
CHD18_RS14200	COG0470	DNA polymerase III
CHD18_RS14210	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CHD18_RS14215	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CHD18_RS14220	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CHD18_RS14285	COG1530	ribonuclease E activity
CHD18_RS14385	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CHD18_RS14395	COG2999	glutathione oxidoreductase activity
CHD18_RS14435	COG3038	cytochrome b561
CHD18_RS14450	COG1560	Kdo2-lipid A biosynthetic process
CHD18_RS14470	COG5645	(Lipo)protein
CHD18_RS14490	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CHD18_RS14550	COG3381	protein complex oligomerization
CHD18_RS14575	COG0673	inositol 2-dehydrogenase activity
CHD18_RS14580	COG2814	Major facilitator Superfamily
CHD18_RS14605	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CHD18_RS14610	COG1737	Transcriptional regulator
CHD18_RS14615	COG1702	phosphate starvation-inducible protein PhoH
CHD18_RS14645	COG1309	transcriptional regulator
CHD18_RS14650	COG3729	General stress protein
CHD18_RS14670	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CHD18_RS14675	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CHD18_RS14675	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CHD18_RS14680	COG4232	protein-disulfide reductase activity
CHD18_RS14735	COG3971	2-oxopent-4-enoate hydratase activity
CHD18_RS14745	COG3384	dioxygenase
CHD18_RS14750	COG1012	belongs to the aldehyde dehydrogenase family
CHD18_RS14760	COG1846	Transcriptional regulator
CHD18_RS14765	COG2368	4-hydroxyphenylacetate
CHD18_RS14785	COG2351	hydroxyisourate hydrolase activity
CHD18_RS14790	COG0745	RESPONSE REGULATOR receiver
CHD18_RS14795	COG2205	protein histidine kinase activity
CHD18_RS14845	COG0670	Belongs to the BI1 family
CHD18_RS14865	COG1881	PFAM PEBP family protein
CHD18_RS14880	COG1832	CoA-binding protein
CHD18_RS14895	COG0210	DNA helicase
CHD18_RS14900	COG3304	Inner membrane component domain
CHD18_RS14905	COG1289	transmembrane transporter activity
CHD18_RS14910	COG3070	regulator of competence-specific genes
CHD18_RS14930	COG1067	ATP-dependent peptidase activity
CHD18_RS14940	COG3130	regulation of translation
CHD18_RS14945	COG3009	Protein conserved in bacteria
CHD18_RS14950	COG3008	intermembrane lipid transfer
CHD18_RS14950	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CHD18_RS14955	COG2995	paraquat-inducible protein a
CHD18_RS14960	COG0488	(ABC) transporter
CHD18_RS14970	COG3217	Mosc domain protein beta barrel domain protein
CHD18_RS14970	COG0633	Ferredoxin
CHD18_RS14985	COG0308	aminopeptidase N
CHD18_RS15060	COG5301	cellulose 1,4-beta-cellobiosidase activity
CHD18_RS15185	COG4220	transposase activity
CHD18_RS15200	COG3179	chitinase
CHD18_RS15275	COG1484	DNA-dependent DNA replication
CHD18_RS15315	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CHD18_RS15335	COG0582	viral genome integration into host DNA
CHD18_RS15345	COG1115	amino acid carrier protein
CHD18_RS15360	COG1522	sequence-specific DNA binding
CHD18_RS15370	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CHD18_RS15380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CHD18_RS15385	COG3108	Peptidase M15
CHD18_RS15395	COG2989	Protein conserved in bacteria
CHD18_RS15405	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CHD18_RS15415	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CHD18_RS15420	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CHD18_RS15425	COG3173	Aminoglycoside phosphotransferase
CHD18_RS15440	COG3214	Protein conserved in bacteria
CHD18_RS15455	COG0658	competence protein
CHD18_RS15455	COG2333	competence protein COMEC
CHD18_RS15465	COG0539	negative regulation of cytoplasmic translation
CHD18_RS15475	COG0501	Belongs to the peptidase M48B family
CHD18_RS15490	COG2323	membrane
CHD18_RS15495	COG1944	ATP diphosphatase activity
CHD18_RS15500	COG2116	formate transmembrane transporter activity
CHD18_RS15505	COG1882	Formate acetyltransferase
CHD18_RS15520	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CHD18_RS15525	COG0531	amino acid
CHD18_RS15535	COG3302	dmso reductase anchor subunit
CHD18_RS15540	COG0437	4 iron, 4 sulfur cluster binding
CHD18_RS15545	COG0243	molybdopterin cofactor binding
CHD18_RS15555	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CHD18_RS15580	COG0492	ferredoxin-NADP+ reductase activity
CHD18_RS15585	COG4988	ABC transporter
CHD18_RS15590	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CHD18_RS15610	COG0583	DNA-binding transcription factor activity
CHD18_RS15620	COG1335	isochorismatase
CHD18_RS15630	COG0542	response to heat
CHD18_RS15640	COG1278	Cold shock
CHD18_RS15655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CHD18_RS15660	COG2990	Protein conserved in bacteria
CHD18_RS15665	COG3593	DNA synthesis involved in DNA repair
CHD18_RS15675	COG2431	L-lysine efflux transmembrane transporter activity
CHD18_RS15685	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CHD18_RS15690	COG0028	Belongs to the TPP enzyme family
CHD18_RS15695	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CHD18_RS15700	COG0702	epimerase
CHD18_RS15705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CHD18_RS15710	COG3023	N-Acetylmuramoyl-L-alanine amidase
CHD18_RS15725	COG1126	abc transporter atp-binding protein
CHD18_RS15730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHD18_RS15735	COG4215	(ABC) transporter
CHD18_RS15740	COG4160	amino acid transport
CHD18_RS15745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHD18_RS15780	COG1177	transmembrane transport
CHD18_RS15785	COG1176	ABC-type spermidine putrescine transport system, permease component I
CHD18_RS15790	COG3842	ATPase activity
CHD18_RS15795	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CHD18_RS15845	COG3226	Transcriptional regulator
CHD18_RS15850	COG0738	Major facilitator superfamily
CHD18_RS15855	COG0561	phosphatase activity
CHD18_RS15860	COG2814	Major facilitator Superfamily
CHD18_RS15865	COG0671	phosphoesterase, PA-phosphatase related
CHD18_RS15870	COG1349	DNA-binding transcription factor activity
CHD18_RS15875	COG1686	Belongs to the peptidase S11 family
CHD18_RS15880	COG0625	glutathione transferase activity
CHD18_RS15885	COG2133	pyrroloquinoline quinone binding
CHD18_RS15895	COG2610	gluconate transmembrane transporter activity
CHD18_RS15900	COG0583	DNA-binding transcription factor activity
CHD18_RS15915	COG1960	acyl-CoA dehydrogenase activity
CHD18_RS15935	COG2301	Belongs to the HpcH HpaI aldolase family
CHD18_RS15960	COG0747	negative chemotaxis
CHD18_RS15985	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CHD18_RS15990	COG1882	Formate acetyltransferase
CHD18_RS15995	COG0561	phosphatase activity
CHD18_RS16025	COG0488	(ABC) transporter
CHD18_RS16030	COG1376	ErfK ybiS ycfS ynhG family protein
CHD18_RS16035	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CHD18_RS16050	COG2194	sulfuric ester hydrolase activity
CHD18_RS16055	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CHD18_RS16070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHD18_RS16075	COG0765	amino acid transport
CHD18_RS16080	COG1126	abc transporter atp-binding protein
CHD18_RS16085	COG0668	transmembrane transport
CHD18_RS16095	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CHD18_RS16105	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CHD18_RS16115	COG0513	Belongs to the DEAD box helicase family
CHD18_RS16120	COG1309	transcriptional regulator
CHD18_RS16130	COG1131	(ABC) transporter
CHD18_RS16135	COG0842	Transport permease protein
CHD18_RS16140	COG0842	Transport permease protein
CHD18_RS16150	COG3568	Endonuclease Exonuclease Phosphatase
CHD18_RS16155	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CHD18_RS16160	COG0392	lysyltransferase activity
CHD18_RS16185	COG0670	Belongs to the BI1 family
CHD18_RS16195	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CHD18_RS16205	COG0521	Mo-molybdopterin cofactor biosynthetic process
CHD18_RS16240	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CHD18_RS16265	COG1881	PFAM PEBP family protein
CHD18_RS16295	COG4677	pectinesterase activity
CHD18_RS16305	COG0561	phosphatase activity
CHD18_RS16315	COG4149	molybdate abc transporter
CHD18_RS16320	COG0725	ABC transporter, periplasmic molybdate-binding protein
CHD18_RS16330	COG2005	Transcriptional regulator
CHD18_RS16330	COG3585	molybdate ion transport
CHD18_RS16335	COG1119	ATPase activity
CHD18_RS16360	COG2017	converts alpha-aldose to the beta-anomer
CHD18_RS16375	COG1120	ATPase activity
CHD18_RS16380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CHD18_RS16405	COG0471	metal ion transport
CHD18_RS16405	COG0490	domain, Protein
CHD18_RS16410	COG0583	DNA-binding transcription factor activity
CHD18_RS16415	COG0583	DNA-binding transcription factor activity
CHD18_RS16425	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CHD18_RS16425	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CHD18_RS16430	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CHD18_RS16440	COG1230	cation diffusion facilitator family transporter
CHD18_RS16480	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CHD18_RS16485	COG2885	chlorophyll binding
CHD18_RS16495	COG3064	Membrane
CHD18_RS16500	COG0848	biopolymer transport protein
CHD18_RS16505	COG0811	peptide transport
CHD18_RS16510	COG0824	Thioesterase
CHD18_RS16515	COG3790	cyd operon protein YbgE
CHD18_RS16520	COG4890	Cyd operon protein YbgT
CHD18_RS16525	COG1294	oxidase, subunit
CHD18_RS16530	COG1271	oxidase subunit
CHD18_RS16535	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CHD18_RS16545	COG0508	dehydrogenase complex catalyzes the overall conversion of
CHD18_RS16550	COG0567	Dehydrogenase, E1 component
CHD18_RS16565	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CHD18_RS16590	COG3180	Ammonia monooxygenase
CHD18_RS16655	COG0582	viral genome integration into host DNA
CHD18_RS16665	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CHD18_RS16670	COG1984	allophanate hydrolase subunit 2
CHD18_RS16675	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CHD18_RS16710	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CHD18_RS16725	COG2205	protein histidine kinase activity
CHD18_RS16730	COG0745	RESPONSE REGULATOR receiver
CHD18_RS16740	COG1982	Orn Lys Arg decarboxylase major
CHD18_RS16745	COG0531	amino acid
CHD18_RS16755	COG0033	Phosphoglucomutase
CHD18_RS16765	COG0596	Alpha beta hydrolase
CHD18_RS16780	COG0735	belongs to the Fur family
CHD18_RS16785	COG0583	DNA-binding transcription factor activity
CHD18_RS16790	COG1053	succinate dehydrogenase
CHD18_RS16835	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CHD18_RS16840	COG1846	Transcriptional regulator
CHD18_RS16840	COG1940	carbohydrate kinase activity
CHD18_RS16845	COG0647	UMP catabolic process
CHD18_RS16850	COG0367	asparagine synthase
CHD18_RS16895	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CHD18_RS16905	COG1702	phosphate starvation-inducible protein PhoH
CHD18_RS16930	COG0765	amino acid transport
CHD18_RS16935	COG0765	amino acid transport
CHD18_RS16940	COG1126	abc transporter atp-binding protein
CHD18_RS16955	COG0443	Heat shock 70 kDa protein
CHD18_RS16960	COG2214	Heat shock protein DnaJ domain protein
CHD18_RS16970	COG2214	Heat shock protein DnaJ domain protein
CHD18_RS16985	COG2888	peptidyl-tyrosine sulfation
CHD18_RS16990	COG3829	transcription factor binding
CHD18_RS16990	COG3290	protein histidine kinase activity
CHD18_RS17020	COG1466	dna polymerase III delta subunit
CHD18_RS17040	COG0799	negative regulation of ribosome biogenesis
CHD18_RS17050	COG0768	penicillin binding
CHD18_RS17055	COG0772	Belongs to the SEDS family
CHD18_RS17060	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CHD18_RS17065	COG1686	Belongs to the peptidase S11 family
CHD18_RS17080	COG0583	DNA-binding transcription factor activity
CHD18_RS17095	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CHD18_RS17120	COG3069	C4-dicarboxylate transmembrane transporter activity
CHD18_RS17125	COG4565	transcriptional regulatory protein
CHD18_RS17130	COG3290	protein histidine kinase activity
CHD18_RS17140	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
CHD18_RS17150	COG2301	Belongs to the HpcH HpaI aldolase family
CHD18_RS17155	COG3051	citrate lyase alpha subunit
CHD18_RS17170	COG0471	metal ion transport
CHD18_RS17175	COG3719	Belongs to the RNase T2 family
CHD18_RS17185	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CHD18_RS17190	COG1063	alcohol dehydrogenase
CHD18_RS17210	COG0243	molybdopterin cofactor binding
CHD18_RS17230	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CHD18_RS17240	COG0583	DNA-binding transcription factor activity
CHD18_RS17245	COG3969	phosphoadenosine phosphosulfate
CHD18_RS17250	COG1475	DNA binding
CHD18_RS17255	COG0436	Aminotransferase
CHD18_RS17260	COG0371	Dehydrogenase
CHD18_RS17265	COG2879	small protein
CHD18_RS17270	COG1966	Carbon starvation protein
CHD18_RS17280	COG1028	Short-chain dehydrogenase reductase Sdr
CHD18_RS17285	COG1535	isochorismatase
CHD18_RS17285	COG3433	isochorismatase activity
CHD18_RS17290	COG1021	2,3-dihydroxybenzoate-AMP ligase
CHD18_RS17295	COG1169	isochorismate synthase
CHD18_RS17300	COG4592	Periplasmic binding protein
CHD18_RS17310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CHD18_RS17315	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CHD18_RS17320	COG1120	ATPase activity
CHD18_RS17325	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CHD18_RS17330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CHD18_RS17330	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CHD18_RS17335	COG3251	PFAM MbtH domain protein
CHD18_RS17340	COG2382	esterase
CHD18_RS17345	COG4771	TonB-dependent receptor
CHD18_RS17350	COG2977	Belongs to the P-Pant transferase superfamily
CHD18_RS17375	COG2315	Protein conserved in bacteria
CHD18_RS17395	COG0668	transmembrane transport
CHD18_RS17400	COG1113	amino acid transport
CHD18_RS17410	COG3059	membrane
CHD18_RS17420	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CHD18_RS17425	COG2207	Transcriptional regulator
CHD18_RS17430	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CHD18_RS17435	COG5002	protein histidine kinase activity
CHD18_RS17445	COG2246	polysaccharide biosynthetic process
CHD18_RS17450	COG0463	Glycosyl transferase, family 2
CHD18_RS17555	COG2501	S4 domain
CHD18_RS17560	COG1988	membrane-bound metal-dependent
CHD18_RS17580	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CHD18_RS17595	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CHD18_RS17600	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CHD18_RS17605	COG0549	Belongs to the carbamate kinase family
CHD18_RS17615	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CHD18_RS17620	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CHD18_RS17625	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CHD18_RS17630	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CHD18_RS17635	COG3257	ureidoglycine aminohydrolase activity
CHD18_RS17640	COG1929	Belongs to the glycerate kinase type-1 family
CHD18_RS17645	COG2233	PERMEase
CHD18_RS17655	COG1953	Uracil, thiamine, allantoin
CHD18_RS17665	COG2084	Dehydrogenase
CHD18_RS17670	COG3622	Belongs to the hyi family
CHD18_RS17675	COG3960	tartronate-semialdehyde synthase activity
CHD18_RS17710	COG1464	Belongs to the NlpA lipoprotein family
CHD18_RS17720	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CHD18_RS17725	COG4181	ATPase activity
CHD18_RS17730	COG2755	lipolytic protein G-D-S-L family
CHD18_RS17735	COG0300	oxidoreductase activity
CHD18_RS17740	COG3118	belongs to the thioredoxin family
CHD18_RS17745	COG0390	transport system, permease component
CHD18_RS17750	COG4619	ABC transporter
CHD18_RS17755	COG0330	HflC and HflK could
CHD18_RS17760	COG1585	Membrane protein implicated in regulation of membrane protease activity
CHD18_RS17770	COG2217	Heavy metal translocating P-type atpase
CHD18_RS17780	COG3735	TraB family
CHD18_RS17795	COG2223	nitrite transmembrane transporter activity
CHD18_RS17800	COG4651	solute:proton antiporter activity
CHD18_RS17800	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CHD18_RS17805	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CHD18_RS17865	COG2832	Protein of unknown function (DUF454)
CHD18_RS17870	COG3923	Primosomal replication protein n
CHD18_RS17880	COG5464	transposase or invertase
CHD18_RS17885	COG1196	nuclear chromosome segregation
CHD18_RS17885	COG3264	Mechanosensitive ion channel
CHD18_RS17890	COG1309	transcriptional regulator
CHD18_RS17895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CHD18_RS17900	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CHD18_RS17915	COG0110	maltose O-acetyltransferase activity
CHD18_RS17935	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CHD18_RS17945	COG3695	enzyme binding
CHD18_RS17950	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CHD18_RS17955	COG1946	Acyl-CoA thioesterase
CHD18_RS17960	COG0004	ammonium transporteR
CHD18_RS17965	COG0347	Belongs to the P(II) protein family
CHD18_RS17970	COG1132	(ABC) transporter
CHD18_RS17975	COG1132	(ABC) transporter
CHD18_RS17980	COG1522	sequence-specific DNA binding
CHD18_RS17995	COG4533	DNA binding
CHD18_RS18005	COG0824	Thioesterase
CHD18_RS18010	COG1555	photosystem II stabilization
CHD18_RS18015	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CHD18_RS18025	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CHD18_RS18055	COG0271	Belongs to the BolA IbaG family
CHD18_RS18065	COG3056	Lipoprotein
CHD18_RS18070	COG2223	nitrite transmembrane transporter activity
CHD18_RS18075	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CHD18_RS18080	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CHD18_RS18085	COG1845	cytochrome c oxidase, subunit III
CHD18_RS18090	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CHD18_RS18115	COG2814	Major facilitator Superfamily
CHD18_RS18145	COG2188	Transcriptional regulator
CHD18_RS18180	COG0142	geranyltranstransferase activity
CHD18_RS18190	COG0667	Aldo Keto reductase
CHD18_RS18195	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CHD18_RS18200	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CHD18_RS18215	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CHD18_RS18215	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CHD18_RS18225	COG4238	major outer membrane lipoprotein
CHD18_RS18260	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CHD18_RS18270	COG1862	Preprotein translocase
CHD18_RS18295	COG0450	alkyl hydroperoxide reductase
CHD18_RS18300	COG0366	Alpha amylase catalytic
CHD18_RS18315	COG5002	protein histidine kinase activity
CHD18_RS18325	COG0420	3'-5' exonuclease activity
CHD18_RS18330	COG0419	ATPase involved in DNA repair
CHD18_RS18335	COG2814	Major facilitator Superfamily
CHD18_RS18340	COG1940	carbohydrate kinase activity
CHD18_RS18355	COG4126	flavin adenine dinucleotide binding
CHD18_RS18375	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CHD18_RS18380	COG3706	GGDEF domain
CHD18_RS18425	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CHD18_RS18435	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CHD18_RS18450	COG0113	porphobilinogen synthase activity
CHD18_RS18460	COG2079	MmgE PrpD family protein
CHD18_RS18485	COG1280	lysine exporter protein (LysE YggA)
CHD18_RS18505	COG1294	oxidase, subunit
CHD18_RS18510	COG1271	oxidase subunit
CHD18_RS18530	COG2814	Major facilitator Superfamily
CHD18_RS18540	COG0789	Transcriptional regulator
CHD18_RS18600	COG2200	EAL domain
CHD18_RS18630	COG3539	Fimbrial protein
CHD18_RS18635	COG3121	Chaperone
CHD18_RS18640	COG3188	usher protein
CHD18_RS18675	COG0179	Fumarylacetoacetate (FAA) hydrolase
CHD18_RS18690	COG2814	Major facilitator Superfamily
CHD18_RS18715	COG0582	viral genome integration into host DNA
CHD18_RS18755	COG2195	Cleaves the N-terminal amino acid of tripeptides
CHD18_RS18760	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CHD18_RS18765	COG1690	Belongs to the RtcB family
CHD18_RS18775	COG3034	peptidoglycan biosynthetic process
CHD18_RS18780	COG0121	glutamine amidotransferase
CHD18_RS18795	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CHD18_RS18970	COG2885	chlorophyll binding
CHD18_RS18970	COG3047	cAMP biosynthetic process
CHD18_RS19065	COG2226	methyltransferase
CHD18_RS19075	COG0741	lytic transglycosylase activity
CHD18_RS19075	COG1388	LysM domain
CHD18_RS19080	COG2226	methyltransferase
CHD18_RS19090	COG2814	Major facilitator Superfamily
CHD18_RS19095	COG0583	DNA-binding transcription factor activity
CHD18_RS19100	COG0656	L-ascorbic acid biosynthetic process
CHD18_RS19135	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CHD18_RS19160	COG1720	tRNA m6t6A37 methyltransferase activity
CHD18_RS19170	COG3015	lipoprotein NlpE involved in copper resistance
CHD18_RS19175	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CHD18_RS19190	COG4568	rho-dependent transcription termination
CHD18_RS19200	COG0346	lactoylglutathione lyase activity
CHD18_RS19205	COG1982	Orn Lys Arg decarboxylase major
CHD18_RS19210	COG3397	chitin binding
CHD18_RS19265	COG0575	Belongs to the CDS family
CHD18_RS19330	COG0477	Major facilitator Superfamily
CHD18_RS19340	COG3835	regulator
CHD18_RS19365	COG2860	membrane
CHD18_RS19395	COG3539	Fimbrial protein
CHD18_RS19400	COG3539	Fimbrial protein
CHD18_RS19405	COG3121	Chaperone
CHD18_RS19410	COG3188	usher protein
CHD18_RS19430	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CHD18_RS19435	COG1120	ATPase activity
CHD18_RS19440	COG4774	siderophore transport
CHD18_RS19445	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CHD18_RS19450	COG1643	Atp-dependent helicase
CHD18_RS19455	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CHD18_RS19480	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CHD18_RS19505	COG3121	Chaperone
CHD18_RS19510	COG3188	usher protein
CHD18_RS19515	COG3539	Fimbrial protein
CHD18_RS19535	COG0726	polysaccharide deacetylase
CHD18_RS19540	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHD18_RS19560	COG3539	Fimbrial protein
CHD18_RS19565	COG0842	Transport permease protein
CHD18_RS19570	COG1131	(ABC) transporter
CHD18_RS19575	COG0288	reversible hydration of carbon dioxide
CHD18_RS19585	COG4993	Dehydrogenase
CHD18_RS19590	COG2132	Multicopper oxidase
CHD18_RS19610	COG1349	DNA-binding transcription factor activity
CHD18_RS19655	COG3064	Membrane
CHD18_RS19670	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CHD18_RS19675	COG0508	dehydrogenase complex catalyzes the overall conversion of
CHD18_RS19680	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CHD18_RS19695	COG2211	Major facilitator Superfamily
CHD18_RS19700	COG3940	Belongs to the glycosyl hydrolase 43 family
CHD18_RS19705	COG3725	Membrane protein required for beta-lactamase induction
CHD18_RS19725	COG4969	Belongs to the N-Me-Phe pilin family
CHD18_RS19735	COG1459	type II secretion system
CHD18_RS19770	COG0494	nUDIX hydrolase
CHD18_RS19790	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CHD18_RS19795	COG0849	cell division
CHD18_RS19820	COG0772	Belongs to the SEDS family
CHD18_RS19835	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CHD18_RS19845	COG0768	penicillin binding
CHD18_RS19955	COG0586	Pfam SNARE associated Golgi protein
CHD18_RS19985	COG0675	Transposase, IS605 OrfB family
CHD18_RS20010	COG0417	DNA replication proofreading
CHD18_RS20090	COG3119	arylsulfatase activity
CHD18_RS20115	COG2271	Major facilitator Superfamily
CHD18_RS20125	COG0644	oxidoreductase
CHD18_RS20270	COG1047	Peptidyl-prolyl cis-trans
CHD18_RS20285	COG0196	riboflavin kinase activity
CHD18_RS20310	COG0583	DNA-binding transcription factor activity
CHD18_RS20330	COG0641	radical SAM
CHD18_RS20335	COG3119	arylsulfatase activity
CHD18_RS20345	COG0737	Belongs to the 5'-nucleotidase family
CHD18_RS20360	COG0583	DNA-binding transcription factor activity
CHD18_RS20380	COG3121	Chaperone
CHD18_RS20385	COG3539	Fimbrial protein
CHD18_RS20400	COG3188	usher protein
CHD18_RS20465	COG4735	regulation of single-species biofilm formation
CHD18_RS20470	COG1584	GPR1 FUN34 yaaH family protein
CHD18_RS20475	COG0521	Mo-molybdopterin cofactor biosynthetic process
CHD18_RS20485	COG1115	amino acid carrier protein
CHD18_RS20495	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CHD18_RS20505	COG0527	aspartate kinase activity
CHD18_RS20505	COG0460	homoserine dehydrogenase
CHD18_RS20515	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CHD18_RS20525	COG0745	RESPONSE REGULATOR receiver
CHD18_RS20545	COG3121	Chaperone
CHD18_RS20565	COG4452	Inner membrane protein CreD
CHD18_RS20570	COG2205	protein histidine kinase activity
CHD18_RS20575	COG0745	RESPONSE REGULATOR receiver
CHD18_RS20580	COG3045	CreA protein
CHD18_RS20585	COG3708	Transcriptional regulator
CHD18_RS20585	COG2207	Transcriptional regulator
CHD18_RS20620	COG0488	(ABC) transporter
CHD18_RS20635	COG0560	Phosphoserine phosphatase
CHD18_RS20645	COG3726	membrane protein affecting hemolysin expression
CHD18_RS20660	COG3539	Fimbrial protein
CHD18_RS20665	COG3121	Chaperone
CHD18_RS20670	COG3188	usher protein
CHD18_RS20700	COG1328	CTP reductase activity
CHD18_RS20705	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CHD18_RS20710	COG0084	hydrolase, TatD family'
CHD18_RS20715	COG4667	esterase of the alpha-beta hydrolase superfamily
CHD18_RS20725	COG2823	Periplasmic or secreted lipoprotein
CHD18_RS20735	COG1011	Hydrolase
CHD18_RS20745	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
CHD18_RS20775	COG3706	GGDEF domain
CHD18_RS20780	COG4114	ferric iron reductase
CHD18_RS20785	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CHD18_RS20790	COG2197	response regulator
CHD18_RS20795	COG2197	response regulator
CHD18_RS20800	COG2966	Psort location CytoplasmicMembrane, score
CHD18_RS20815	COG1484	DNA-dependent DNA replication
CHD18_RS20835	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CHD18_RS20840	COG3716	PTS system mannose fructose sorbose family IID component
CHD18_RS20845	COG3715	PTS system
CHD18_RS20850	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CHD18_RS20865	COG0840	transmembrane signaling receptor activity
CHD18_RS20870	COG1966	Carbon starvation protein
CHD18_RS20875	COG2879	small protein
CHD18_RS20880	COG0523	cobalamin synthesis protein
CHD18_RS20900	COG0732	type I restriction modification DNA specificity domain
CHD18_RS20915	COG3586	endonuclease activity
CHD18_RS20930	COG1012	belongs to the aldehyde dehydrogenase family
CHD18_RS20935	COG5464	transposase or invertase
CHD18_RS20945	COG2733	membrane
CHD18_RS20950	COG0477	Major facilitator Superfamily
CHD18_RS20955	COG3366	ferrous iron transmembrane transporter activity
CHD18_RS20960	COG0700	Nucleoside recognition
CHD18_RS20965	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CHD18_RS20970	COG0583	DNA-binding transcription factor activity
CHD18_RS20995	COG2186	Transcriptional regulator
CHD18_RS21005	COG0412	Dienelactone hydrolase
CHD18_RS21040	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CHD18_RS21130	COG0582	viral genome integration into host DNA
CHD18_RS21140	COG1064	alcohol dehydrogenase
CHD18_RS21145	COG3265	gluconokinase activity
CHD18_RS21150	COG1063	alcohol dehydrogenase
CHD18_RS21155	COG1028	Short-chain dehydrogenase reductase Sdr
CHD18_RS21160	COG2610	gluconate transmembrane transporter activity
CHD18_RS21165	COG1609	Transcriptional regulator
CHD18_RS21170	COG0795	lipopolysaccharide-transporting ATPase activity
CHD18_RS21175	COG0795	lipopolysaccharide-transporting ATPase activity
CHD18_RS21195	COG2927	DNA polymerase III (CHI subunit)
CHD18_RS21235	COG2731	YhcH YjgK YiaL family protein
CHD18_RS21260	COG1288	antiporter activity
CHD18_RS21265	COG1438	arginine binding
CHD18_RS21310	COG1263	PTS System
CHD18_RS21310	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CHD18_RS21315	COG0366	Alpha amylase catalytic
CHD18_RS21330	COG2026	Addiction module toxin, RelE StbE family
CHD18_RS21335	COG3077	Addiction module antitoxin, RelB DinJ family
CHD18_RS21340	COG3711	transcriptional antiterminator
CHD18_RS21340	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHD18_RS21355	COG3964	amidohydrolase
CHD18_RS21390	COG0312	modulator of DNA gyrase
CHD18_RS21400	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CHD18_RS21415	COG3964	amidohydrolase
CHD18_RS21420	COG2271	Major facilitator Superfamily
CHD18_RS21425	COG2105	PFAM AIG2 family protein
CHD18_RS21445	COG1253	flavin adenine dinucleotide binding
CHD18_RS21460	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CHD18_RS21480	COG1733	regulation of RNA biosynthetic process
CHD18_RS21485	COG0702	epimerase
CHD18_RS21490	COG0697	spore germination
CHD18_RS21510	COG1113	amino acid transport
CHD18_RS21515	COG0545	Peptidyl-prolyl cis-trans isomerase
CHD18_RS21525	COG3061	Opacity-associated protein A
CHD18_RS21540	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CHD18_RS21610	COG1073	alpha beta
CHD18_RS21615	COG3650	response to hydrogen peroxide
CHD18_RS21625	COG1960	acyl-CoA dehydrogenase activity
CHD18_RS21630	COG0754	glutathionylspermidine amidase activity
CHD18_RS21635	COG5463	Belongs to the UPF0441 family
CHD18_RS21640	COG3766	membrane
CHD18_RS21655	COG1842	Phage shock protein A
CHD18_RS21660	COG3789	protein conserved in bacteria
CHD18_RS21685	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CHD18_RS21690	COG0330	HflC and HflK could
CHD18_RS21695	COG0330	HflC and HflK could
CHD18_RS21700	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CHD18_RS21725	COG0802	atpase or kinase
CHD18_RS21730	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CHD18_RS21730	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CHD18_RS21755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHD18_RS21775	COG3264	Mechanosensitive ion channel
CHD18_RS21775	COG1511	domain protein
CHD18_RS21795	COG1053	succinate dehydrogenase
CHD18_RS21800	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CHD18_RS21830	COG5510	response to toxic substance
CHD18_RS21875	COG0531	amino acid
CHD18_RS21880	COG3030	protein affecting phage T7 exclusion by the F plasmid
CHD18_RS21885	COG1027	Aspartate ammonia-lyase
CHD18_RS21890	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CHD18_RS21905	COG1309	transcriptional regulator
CHD18_RS21955	COG2197	response regulator
CHD18_RS21980	COG3381	protein complex oligomerization
CHD18_RS21985	COG3302	dmso reductase anchor subunit
CHD18_RS21990	COG0437	4 iron, 4 sulfur cluster binding
CHD18_RS21995	COG0243	molybdopterin cofactor binding
CHD18_RS22000	COG3290	protein histidine kinase activity
CHD18_RS22005	COG4565	transcriptional regulatory protein
CHD18_RS22015	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CHD18_RS22020	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CHD18_RS22020	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CHD18_RS22035	COG2169	Transcriptional regulator
CHD18_RS22040	COG1982	Orn Lys Arg decarboxylase major
CHD18_RS22045	COG2207	Transcriptional regulator
CHD18_RS22050	COG0531	amino acid
CHD18_RS22080	COG2824	Alkylphosphonate utilization operon protein PhnA
CHD18_RS22085	COG2764	glyoxalase bleomycin resistance protein dioxygenase
CHD18_RS22105	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CHD18_RS22110	COG1301	dicarboxylic acid transport
CHD18_RS22115	COG4235	cytochrome complex assembly
CHD18_RS22120	COG1138	Cytochrome C-type biogenesis protein
CHD18_RS22125	COG3301	Polysulphide reductase, NrfD
CHD18_RS22130	COG0437	4 iron, 4 sulfur cluster binding
CHD18_RS22135	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
CHD18_RS22150	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CHD18_RS22160	COG3162	membrane
CHD18_RS22170	COG1346	cytolysis
CHD18_RS22175	COG1380	Effector of murein hydrolase LrgA
CHD18_RS22180	COG0583	DNA-binding transcription factor activity
CHD18_RS22185	COG0025	NhaP-type Na H and K H
CHD18_RS22195	COG2252	PERMEase
CHD18_RS22220	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CHD18_RS22285	COG2315	Protein conserved in bacteria
CHD18_RS22330	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CHD18_RS22340	COG0735	belongs to the Fur family
CHD18_RS22355	COG0534	Mate efflux family protein
CHD18_RS22365	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CHD18_RS22410	COG3833	ABC-type maltose transport systems, permease component
CHD18_RS22420	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CHD18_RS22445	COG0527	aspartate kinase activity
CHD18_RS22530	COG2246	polysaccharide biosynthetic process
CHD18_RS22560	COG5301	cellulose 1,4-beta-cellobiosidase activity
CHD18_RS22565	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CHD18_RS22580	COG0561	phosphatase activity
CHD18_RS22585	COG1349	DNA-binding transcription factor activity
CHD18_RS22600	COG3122	Protein conserved in bacteria
CHD18_RS22645	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CHD18_RS22690	COG0151	Belongs to the GarS family
CHD18_RS22695	COG2204	response regulator
CHD18_RS22755	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CHD18_RS22760	COG2104	thiamine diphosphate biosynthetic process
CHD18_RS22830	COG0250	Participates in transcription elongation, termination and antitermination
CHD18_RS22885	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CHD18_RS22950	COG0583	DNA-binding transcription factor activity
CHD18_RS22995	COG2207	Transcriptional regulator
CHD18_RS23000	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CHD18_RS23005	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CHD18_RS23010	COG1882	Formate acetyltransferase
CHD18_RS23015	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CHD18_RS23020	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CHD18_RS23025	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHD18_RS23025	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CHD18_RS23025	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHD18_RS23035	COG0371	Dehydrogenase
CHD18_RS23040	COG3738	Protein conserved in bacteria
CHD18_RS23055	COG0737	Belongs to the 5'-nucleotidase family
CHD18_RS23070	COG0668	transmembrane transport
CHD18_RS23075	COG0460	homoserine dehydrogenase
CHD18_RS23075	COG0527	aspartate kinase activity
CHD18_RS23080	COG0626	cystathionine gamma-synthase activity
CHD18_RS23105	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CHD18_RS23110	COG1609	Transcriptional regulator
CHD18_RS23115	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CHD18_RS23130	COG1575	Belongs to the MenA family. Type 1 subfamily
CHD18_RS23145	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CHD18_RS23155	COG1494	fructose-1,6-bisphosphatase
CHD18_RS23165	COG3152	Membrane
CHD18_RS23220	COG1070	Carbohydrate kinase
CHD18_RS23240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CHD18_RS23250	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CHD18_RS23255	COG2211	Major facilitator Superfamily
CHD18_RS23280	COG3678	ATP-independent chaperone mediated protein folding
CHD18_RS23285	COG0745	RESPONSE REGULATOR receiver
CHD18_RS23290	COG2205	protein histidine kinase activity
CHD18_RS23305	COG2258	MOSC domain
CHD18_RS23310	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CHD18_RS23320	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CHD18_RS23360	COG4806	L-rhamnose isomerase
CHD18_RS23370	COG1454	alcohol dehydrogenase
CHD18_RS23385	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CHD18_RS23410	COG0243	molybdopterin cofactor binding
CHD18_RS23410	COG3383	formate dehydrogenase (NAD+) activity
CHD18_RS23415	COG0243	molybdopterin cofactor binding
CHD18_RS23415	COG3383	formate dehydrogenase (NAD+) activity
CHD18_RS23420	COG0437	4 iron, 4 sulfur cluster binding
CHD18_RS23425	COG2864	formate dehydrogenase
CHD18_RS23440	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
CHD18_RS23450	COG4680	protein conserved in bacteria
CHD18_RS23455	COG5499	transcription regulator containing HTH domain
CHD18_RS23460	COG0456	acetyltransferase
CHD18_RS23475	COG1011	Hydrolase
CHD18_RS23480	COG1349	DNA-binding transcription factor activity
CHD18_RS23485	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CHD18_RS23495	COG3684	Belongs to the aldolase LacD family
CHD18_RS23505	COG2017	converts alpha-aldose to the beta-anomer
CHD18_RS23510	COG1501	Belongs to the glycosyl hydrolase 31 family
CHD18_RS23600	COG0204	Acyl-transferase
CHD18_RS23615	COG3084	Protein conserved in bacteria
CHD18_RS23625	COG1763	Mo-molybdopterin cofactor biosynthetic process
CHD18_RS23670	COG1739	Uncharacterized protein family UPF0029
CHD18_RS23715	COG0805	protein transport
CHD18_RS23760	COG0641	radical SAM
CHD18_RS23780	COG0561	phosphatase activity
CHD18_RS23785	COG2267	carboxylic ester hydrolase activity
CHD18_RS23790	COG1280	lysine exporter protein (LysE YggA)
CHD18_RS23845	COG1011	Hydrolase
CHD18_RS23905	COG2959	enzyme of heme biosynthesis
CHD18_RS23910	COG3071	HemY protein
CHD18_RS23955	COG2244	polysaccharide biosynthetic process
CHD18_RS23960	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CHD18_RS23965	COG0456	acetyltransferase
CHD18_RS23970	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CHD18_RS23975	COG1088	dTDP-glucose 4,6-dehydratase activity
CHD18_RS23980	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CHD18_RS24010	COG3118	belongs to the thioredoxin family
CHD18_RS24035	COG3201	nicotinamide mononucleotide transporter
CHD18_RS24085	COG3978	acetolactate synthase activity
CHD18_RS24145	COG2186	Transcriptional regulator
CHD18_RS24150	COG0477	Major facilitator Superfamily
CHD18_RS24155	COG1609	Transcriptional regulator
CHD18_RS24160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CHD18_RS24170	COG1172	Belongs to the binding-protein-dependent transport system permease family
CHD18_RS24205	COG1522	sequence-specific DNA binding
CHD18_RS24210	COG0716	FMN binding
CHD18_RS24230	COG3312	ion transport
CHD18_RS24295	COG4533	DNA binding
CHD18_RS24300	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CHD18_RS24305	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CHD18_RS24305	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CHD18_RS24305	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CHD18_RS24310	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CHD18_RS24315	COG0573	inorganic phosphate transmembrane transporter activity
CHD18_RS24320	COG0581	inorganic phosphate transmembrane transporter activity
CHD18_RS24330	COG0704	Plays a role in the regulation of phosphate uptake
CHD18_RS24335	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CHD18_RS24345	COG2252	PERMEase
CHD18_RS24350	COG0431	NADPH-dependent FMN reductase
CHD18_RS24355	COG2091	lysine biosynthetic process via aminoadipic acid